Guide to the Human Genome
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Search of human proteins with 112382212

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo
sapiens]
         (1268 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sap...  2551   0.0  
gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap...  2464   0.0  
gi|116174780 SEC24 related gene family, member A [Homo sapiens]      1229   0.0  
gi|38373671 SEC24-related protein C [Homo sapiens]                    426   e-119
gi|38373669 SEC24-related protein C [Homo sapiens]                    426   e-119
gi|190343021 Sec24-related protein D [Homo sapiens]                   395   e-109
gi|14591924 Sec23 homolog B [Homo sapiens]                             83   1e-15
gi|14591926 Sec23 homolog B [Homo sapiens]                             83   1e-15
gi|14591928 Sec23 homolog B [Homo sapiens]                             83   1e-15
gi|38202214 SEC23-related protein A [Homo sapiens]                     76   2e-13
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        62   3e-09
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                60   1e-08
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                60   1e-08
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                60   1e-08
gi|91982772 mucin 17 [Homo sapiens]                                    59   3e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         59   3e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   4e-08
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  59   4e-08
gi|188497758 ubiquitin associated protein 2-like isoform a [Homo...    56   2e-07
gi|188497756 ubiquitin associated protein 2-like isoform b [Homo...    56   2e-07
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...    55   3e-07
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...    55   3e-07
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         55   6e-07
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             55   6e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          54   7e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          54   7e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          54   7e-07
gi|83367077 mucin 16 [Homo sapiens]                                    54   9e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    54   9e-07
gi|151301154 mucin 6, gastric [Homo sapiens]                           54   1e-06

>gi|112382212 SEC24 (S. cerevisiae) homolog B isoform a [Homo sapiens]
          Length = 1268

 Score = 2551 bits (6612), Expect = 0.0
 Identities = 1268/1268 (100%), Positives = 1268/1268 (100%)

Query: 1    MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLH 60
            MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLH
Sbjct: 1    MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLH 60

Query: 61   HQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG 120
            HQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG
Sbjct: 61   HQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG 120

Query: 121  PPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTC 180
            PPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTC
Sbjct: 121  PPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTC 180

Query: 181  GHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPL 240
            GHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPL
Sbjct: 181  GHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPL 240

Query: 241  PPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCP 300
            PPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCP
Sbjct: 241  PPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCP 300

Query: 301  VMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEY 360
            VMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEY
Sbjct: 301  VMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEY 360

Query: 361  VNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSS 420
            VNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSS
Sbjct: 361  VNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSS 420

Query: 421  SASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISG 480
            SASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISG
Sbjct: 421  SASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISG 480

Query: 481  VQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVW 540
            VQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVW
Sbjct: 481  VQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVW 540

Query: 541  APVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSN 600
            APVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSN
Sbjct: 541  APVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSN 600

Query: 601  TIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNS 660
            TIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNS
Sbjct: 601  TIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNS 660

Query: 661  TVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGF 720
            TVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGF
Sbjct: 661  TVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGF 720

Query: 721  MTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMF 780
            MTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMF
Sbjct: 721  MTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMF 780

Query: 781  TNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQH 840
            TNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQH
Sbjct: 781  TNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQH 840

Query: 841  LGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNP 900
            LGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNP
Sbjct: 841  LGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNP 900

Query: 901  SQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGF 960
            SQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGF
Sbjct: 901  SQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGF 960

Query: 961  AVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAIC 1020
            AVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAIC
Sbjct: 961  AVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAIC 1020

Query: 1021 LLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLA 1080
            LLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLA
Sbjct: 1021 LLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLA 1080

Query: 1081 LLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIV 1140
            LLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIV
Sbjct: 1081 LLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIV 1140

Query: 1141 PQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLP 1200
            PQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLP
Sbjct: 1141 PQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLP 1200

Query: 1201 ELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLL 1260
            ELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLL
Sbjct: 1201 ELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLL 1260

Query: 1261 HVQQQICK 1268
            HVQQQICK
Sbjct: 1261 HVQQQICK 1268


>gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sapiens]
          Length = 1233

 Score = 2464 bits (6387), Expect = 0.0
 Identities = 1233/1268 (97%), Positives = 1233/1268 (97%), Gaps = 35/1268 (2%)

Query: 1    MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLH 60
            MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLH
Sbjct: 1    MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLH 60

Query: 61   HQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG 120
            HQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG
Sbjct: 61   HQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG 120

Query: 121  PPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTC 180
            PPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTC
Sbjct: 121  PPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTC 180

Query: 181  GHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPL 240
            GHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPL
Sbjct: 181  GHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPL 240

Query: 241  PPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCP 300
            PPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCP
Sbjct: 241  PPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCP 300

Query: 301  VMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEY 360
            VMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGV     
Sbjct: 301  VMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGV----- 355

Query: 361  VNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSS 420
                                          DSSSTTSSASPMPNSYDALEGGSYPDMLSS
Sbjct: 356  ------------------------------DSSSTTSSASPMPNSYDALEGGSYPDMLSS 385

Query: 421  SASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISG 480
            SASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISG
Sbjct: 386  SASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISG 445

Query: 481  VQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVW 540
            VQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVW
Sbjct: 446  VQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVW 505

Query: 541  APVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSN 600
            APVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSN
Sbjct: 506  APVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSN 565

Query: 601  TIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNS 660
            TIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNS
Sbjct: 566  TIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEVQNS 625

Query: 661  TVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGF 720
            TVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGF
Sbjct: 626  TVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGF 685

Query: 721  MTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMF 780
            MTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMF
Sbjct: 686  MTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNALPNMF 745

Query: 781  TNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQH 840
            TNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQH
Sbjct: 746  TNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSSTKVVQH 805

Query: 841  LGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNP 900
            LGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNP
Sbjct: 806  LGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSFHYTHNP 865

Query: 901  SQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGF 960
            SQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGF
Sbjct: 866  SQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGF 925

Query: 961  AVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAIC 1020
            AVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAIC
Sbjct: 926  AVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAIC 985

Query: 1021 LLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLA 1080
            LLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLA
Sbjct: 986  LLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLA 1045

Query: 1081 LLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIV 1140
            LLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIV
Sbjct: 1046 LLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVHVNDRIV 1105

Query: 1141 PQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLP 1200
            PQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLP
Sbjct: 1106 PQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQKMTHLP 1165

Query: 1201 ELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLL 1260
            ELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLL
Sbjct: 1166 ELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFSYYEFLL 1225

Query: 1261 HVQQQICK 1268
            HVQQQICK
Sbjct: 1226 HVQQQICK 1233


>gi|116174780 SEC24 related gene family, member A [Homo sapiens]
          Length = 1093

 Score = 1229 bits (3180), Expect = 0.0
 Identities = 663/1154 (57%), Positives = 818/1154 (70%), Gaps = 92/1154 (7%)

Query: 136  GAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGF----PSTCGHYAMSTVSNA 191
            GA +S    + +A    S + N     A+ S+  SV SQG+    P +  H   +   N 
Sbjct: 11   GAPASLQAQNGAALASGSPYTNGPVQNALLSSQESV-SQGYNFQLPGSYPHPIPAKTLNP 69

Query: 192  AYPSVSYPSLPAGDTYGQMFTSQNAPTV-RPVKDNSFSGQNTAISHPSPLPPLPSQQHHQ 250
                 +Y     G + G   T    P    PV  +  SG       P+P  PLP+ Q+  
Sbjct: 70   VSGQSNY-----GGSQGSGQTLNRPPVASNPVTPSLHSG-------PAPRMPLPASQNPA 117

Query: 251  QQSLSGYSTLTWSSPGLP-STQDNL--IRNHTGSLAVANNNPTITVADSLSC-------- 299
               +   S L  ++   P + Q N     + T     A++ PT++   SL+         
Sbjct: 118  TTPMPSSSFLPEANLPPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSG 177

Query: 300  -PVMQNV---QPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGV 355
             P +QN      P   P+V+  L  +    +   PP A  P  PV ++T           
Sbjct: 178  YPSLQNSFIKSGPSVPPLVNPPLPTTFQPGAPHGPPPAGGP-PPVRALTP---------- 226

Query: 356  QYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYP 415
                 + +     P PL +++ ++E        G+ +S+T + +  + +SYD +EGG   
Sbjct: 227  -----LTSSYRDVPQPLFNSAVNQE--------GI-TSNTNNGSMVVHSSYDEIEGGGLL 272

Query: 416  DMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATA 475
                 +  +P                            KM++  GY YP+L PGYQN T 
Sbjct: 273  ATPQLTNKNP----------------------------KMSRSVGYSYPSLPPGYQNTTP 304

Query: 476  PLISGVQPSNPVY-SGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNIL 534
            P  +GV PS+  Y SG Q + Q   G N L++S+ GLSLQ    PE LR VNL QERN+L
Sbjct: 305  PGATGVPPSSLNYPSGPQAFTQTPLGANHLTTSMSGLSLQ----PEGLRVVNLLQERNML 360

Query: 535  PMTPVWAPVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQL 594
            P TP+  PVPNL+ D++KLNC+P+ FRCTLT+IPQTQALLNKAKLPLGLLLHPF+DL QL
Sbjct: 361  PSTPLKPPVPNLHEDIQKLNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQL 420

Query: 595  PVITSNTIVRCRSCRTYINPFVSFIDQRRWKCNLCYRVNDVPEEFMYNPLTRSYGEPHKR 654
            PV+TS+TIVRCRSCRTYINPFVSF+DQRRWKCNLCYRVNDVPEEF+YNPLTR YGEPH+R
Sbjct: 421  PVVTSSTIVRCRSCRTYINPFVSFLDQRRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRR 480

Query: 655  PEVQNSTVEFIASSDYMLRPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDS 714
            PEVQN+T+EF+A S+YMLRPPQP VYLFV DVSHNAVE GYL  +CQSLL+NLD LPG++
Sbjct: 481  PEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLPGNT 540

Query: 715  RTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLN 774
            RT+IGF+TFDSTIHFY LQE LSQPQMLIVSDI+DVF+P P++LLVNL ESKEL++DLL 
Sbjct: 541  RTKIGFITFDSTIHFYGLQESLSQPQMLIVSDIEDVFIPMPENLLVNLNESKELVQDLLK 600

Query: 775  ALPNMFTNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSREDPNQRSS 834
             LP MFT T ET SALGPALQAAFKLMSPTGGR+SVFQTQLP+LG G L+ RE+PN RSS
Sbjct: 601  TLPQMFTKTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPNHRSS 660

Query: 835  TKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIYYYPSF 894
             K + H+ P+TDFYKKLALDCSGQQ AVDLFLLS QYSDLASL C+S+YSAG +YYYPS+
Sbjct: 661  AKDI-HMTPSTDFYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSY 719

Query: 895  HYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLLSLANI 954
            H+ HNP Q +KLQK+L+RYLTRKIGFEAVMRIRCTKGLS+HTFHGNFFVRSTDLLSL N+
Sbjct: 720  HHQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNV 779

Query: 955  NPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVD 1014
            NPDAG+AVQ+S+EESLTDT LV FQ+ALLYTSSKGERRIRVHTLCLPVVS+L DV+ G D
Sbjct: 780  NPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGAD 839

Query: 1015 VQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLF 1074
            VQA   LLANMAVDRS+++SLSDARDALVNAV+DSLSAY S+V + Q   LM P SL+LF
Sbjct: 840  VQAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSVLSNQQPGLMVPFSLRLF 899

Query: 1075 PLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEGAVH 1134
            PL+VLALLKQK+F+TGT+ RLD+R++AMCQ+K+QPLV+LM   HP+LYR+D L+DEGA++
Sbjct: 900  PLFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEGALN 959

Query: 1135 VNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTNFASIPQ 1194
            ++DR +PQPP+ +LS EKL+R+GAFLMD GSV  +WVGK C  NF+  VLG  N+ASIPQ
Sbjct: 960  ISDRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQ 1019

Query: 1195 KMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDRTEAAFS 1254
             MT LPELDT  S R  +FI+WLR+ RP  PIL++++DESP KA F Q++IEDRTE+A S
Sbjct: 1020 PMTDLPELDTPESARIIAFISWLREQRPFFPILYVIRDESPMKANFLQNMIEDRTESALS 1079

Query: 1255 YYEFLLHVQQQICK 1268
            YYEFLLH+QQQ+ K
Sbjct: 1080 YYEFLLHIQQQVNK 1093


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score =  426 bits (1096), Expect = e-119
 Identities = 324/1099 (29%), Positives = 508/1099 (46%), Gaps = 77/1099 (7%)

Query: 199  PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYS 258
            P++P G   G +   Q  P     +    SG   A +  +P       Q  Q    +G S
Sbjct: 37   PAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPS 96

Query: 259  TLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVL 318
            + T     LP +Q          LA   N P          PV+Q   PP +S  V+T L
Sbjct: 97   S-TVQMQRLPGSQP-----FGSPLAPVGNQP----------PVLQPYGPPPTSAQVATQL 140

Query: 319  SGSSGSSSTR-TPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSD 377
            SG   S +    PP++     P TS+   S      G+ YG Y   QA     PLS    
Sbjct: 141  SGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGL-YGSYPQGQAP----PLSQAQG 195

Query: 378  DEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPAS 437
                +     A   +SS T  AS  P    ++ G   P       S   P+    P P +
Sbjct: 196  HPGIQTPQRSAPSQASSFTPPASGGPR-LPSMTGPLLPGQSFGGPSVSQPNHVSSP-PQA 253

Query: 438  APAPASAPAPVVPQPSKMAKPFGYGYPTLQPG-YQNATAPLIS--GVQPSNPVYSGFQQY 494
             P       P+ P P  M  P   GY   Q G +  A  P  +  G  P+ P +      
Sbjct: 254  LPPGTQMTGPLGPLPP-MHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGP 312

Query: 495  PQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNL---NADLK 551
            PQ  P           L   + P P  +   +         +T V   VP L   N  +K
Sbjct: 313  PQPLPPKR--------LDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTNFLVK 364

Query: 552  KL-NCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIV------- 603
               N SP   RCT  NIP T  +  +A++PL  ++ P   L +LP   ++  V       
Sbjct: 365  DQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKP---LARLPPEEASPYVVDHGESG 421

Query: 604  --RCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEE-FMYNPLTRSYGEPHKRPEVQN 659
              RC  C+ Y+ PF+ FI+  RR++C  C  +NDVP + F +   T    + + RPE+  
Sbjct: 422  PLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSL 481

Query: 660  STVEFIASSDYMLRP--PQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGD---- 713
             + EF+A+ DY      P P  ++F++DVS+NA+  G + +LC+ L   LD LP +    
Sbjct: 482  GSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGAE 541

Query: 714  -SRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDL 772
             S  R+GF+T++  +HFYN++  L+QPQM++VSD+ D+F+P  D  LVN+ ES+ +I  L
Sbjct: 542  ESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITSL 601

Query: 773  LNALPNMFTNTRETHSALGPALQAAFKLM--SPTGGRVSVFQTQLPSLGA-GLLQSREDP 829
            L+ +P MF +TRET +   P +QA  + +  +   G++ +F T LP   A G L++R+D 
Sbjct: 602  LDQIPEMFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDDR 661

Query: 830  NQRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIY 889
               ++ K      P T  Y+ LA +C  Q   VDLFL  +QY D+A+L+ + + + G +Y
Sbjct: 662  KLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVY 721

Query: 890  YYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLL 949
             Y SF   ++    E+   DL+R + + +GF+AVMR+R + G+    F G F++ +T  +
Sbjct: 722  KYASFQVEND---QERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDV 778

Query: 950  SLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADV 1009
             LA ++ D    V+   ++ L + S    Q ALLYTS  G+RR+R+H L L   + LAD+
Sbjct: 779  ELAGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADL 838

Query: 1010 YAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSA-LMAP 1068
            Y   +    I  +A  A    ++S +   RD L+      L+ Y    ++   +  L+ P
Sbjct: 839  YRNCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILP 898

Query: 1069 SSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLT 1128
              +KL P+Y+  +LK    + G     DDR Y    + S  +       +P L  + +  
Sbjct: 899  ECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSP 958

Query: 1129 DEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTN 1188
             E           +PP  + S E+L+    +L++ G   ++WVG       ++ +   ++
Sbjct: 959  VESTT--------EPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSS 1010

Query: 1189 FASIPQKMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDR 1248
            F+ I   ++ LP LD   S++ R  I  LR  R     L +VK E   +  F   L+ED+
Sbjct: 1011 FSQITSGLSVLPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDK 1070

Query: 1249 T-EAAFSYYEFLLHVQQQI 1266
            +     SY +FL H+ ++I
Sbjct: 1071 SLSGGASYVDFLCHMHKEI 1089



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 78/289 (26%), Positives = 95/289 (32%), Gaps = 66/289 (22%)

Query: 4   PAGSSHPAASARIPPKFGGAAVSGAAAPAGP-GA--GPAPHQQNGPAQNQMQVPSGYGLH 60
           P G   P         +GG   SG+ APA P GA  GP P  Q  P Q   + P   G  
Sbjct: 12  PFGQPQPIYPGYHQSSYGGQ--SGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG-- 67

Query: 61  HQNYIAPSGHYSQGPGKMTSLPLDTQCGD-YYSALYTVPTQNVTPNTVNQQ--PGAQQ-- 115
                AP    +Q P           CG   Y        QN   +TV  Q  PG+Q   
Sbjct: 68  -----APPASTAQAP-----------CGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFG 111

Query: 116 ------------LYSRGPP------APHIVGSTLGSFQGAASSASHL----HTSASQPYS 153
                       L   GPP      A  + G  +      A  +S L     TS +    
Sbjct: 112 SPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASG 171

Query: 154 SFVNH--YNSPAMYSASSSVASQGFP--STCGHYAMSTVSNAAYPSVSYPSLPA------ 203
           SF N   Y S     A     +QG P   T    A S  S+   P+   P LP+      
Sbjct: 172 SFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLL 231

Query: 204 -GDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQ 251
            G ++G    SQ      P +      Q T      PL PLP     QQ
Sbjct: 232 PGQSFGGPSVSQPNHVSSPPQALPPGTQMT-----GPLGPLPPMHSPQQ 275


>gi|38373669 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score =  426 bits (1096), Expect = e-119
 Identities = 324/1099 (29%), Positives = 508/1099 (46%), Gaps = 77/1099 (7%)

Query: 199  PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYS 258
            P++P G   G +   Q  P     +    SG   A +  +P       Q  Q    +G S
Sbjct: 37   PAIPYGAYNGPVPGYQQTPPQGMSRAPPSSGAPPASTAQAPCGQAAYGQFGQGDVQNGPS 96

Query: 259  TLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVL 318
            + T     LP +Q          LA   N P          PV+Q   PP +S  V+T L
Sbjct: 97   S-TVQMQRLPGSQP-----FGSPLAPVGNQP----------PVLQPYGPPPTSAQVATQL 140

Query: 319  SGSSGSSSTR-TPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSD 377
            SG   S +    PP++     P TS+   S      G+ YG Y   QA     PLS    
Sbjct: 141  SGMQISGAVAPAPPSSGLGFGPPTSLASASGSFPNSGL-YGSYPQGQAP----PLSQAQG 195

Query: 378  DEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPAS 437
                +     A   +SS T  AS  P    ++ G   P       S   P+    P P +
Sbjct: 196  HPGIQTPQRSAPSQASSFTPPASGGPR-LPSMTGPLLPGQSFGGPSVSQPNHVSSP-PQA 253

Query: 438  APAPASAPAPVVPQPSKMAKPFGYGYPTLQPG-YQNATAPLIS--GVQPSNPVYSGFQQY 494
             P       P+ P P  M  P   GY   Q G +  A  P  +  G  P+ P +      
Sbjct: 254  LPPGTQMTGPLGPLPP-MHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGP 312

Query: 495  PQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNL---NADLK 551
            PQ  P           L   + P P  +   +         +T V   VP L   N  +K
Sbjct: 313  PQPLPPKR--------LDPDAIPSPIQVIEDDRNNRGTEPFVTGVRGQVPPLVTTNFLVK 364

Query: 552  KL-NCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIV------- 603
               N SP   RCT  NIP T  +  +A++PL  ++ P   L +LP   ++  V       
Sbjct: 365  DQGNASPRYIRCTSYNIPCTSDMAKQAQVPLAAVIKP---LARLPPEEASPYVVDHGESG 421

Query: 604  --RCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEE-FMYNPLTRSYGEPHKRPEVQN 659
              RC  C+ Y+ PF+ FI+  RR++C  C  +NDVP + F +   T    + + RPE+  
Sbjct: 422  PLRCNRCKAYMCPFMQFIEGGRRFQCCFCSCINDVPPQYFQHLDHTGKRVDAYDRPELSL 481

Query: 660  STVEFIASSDYMLRP--PQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGD---- 713
             + EF+A+ DY      P P  ++F++DVS+NA+  G + +LC+ L   LD LP +    
Sbjct: 482  GSYEFLATVDYCKNNKFPSPPAFIFMIDVSYNAIRTGLVRLLCEELKSLLDFLPREGGAE 541

Query: 714  -SRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDL 772
             S  R+GF+T++  +HFYN++  L+QPQM++VSD+ D+F+P  D  LVN+ ES+ +I  L
Sbjct: 542  ESAIRVGFVTYNKVLHFYNVKSSLAQPQMMVVSDVADMFVPLLDGFLVNVNESRAVITSL 601

Query: 773  LNALPNMFTNTRETHSALGPALQAAFKLM--SPTGGRVSVFQTQLPSLGA-GLLQSREDP 829
            L+ +P MF +TRET +   P +QA  + +  +   G++ +F T LP   A G L++R+D 
Sbjct: 602  LDQIPEMFADTRETETVFVPVIQAGMEALKAAECAGKLFLFHTSLPIAEAPGKLKNRDDR 661

Query: 830  NQRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLASLACMSKYSAGCIY 889
               ++ K      P T  Y+ LA +C  Q   VDLFL  +QY D+A+L+ + + + G +Y
Sbjct: 662  KLINTDKEKTLFQPQTGAYQTLAKECVAQGCCVDLFLFPNQYVDVATLSVVPQLTGGSVY 721

Query: 890  YYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLSMHTFHGNFFVRSTDLL 949
             Y SF   ++    E+   DL+R + + +GF+AVMR+R + G+    F G F++ +T  +
Sbjct: 722  KYASFQVEND---QERFLSDLRRDVQKVVGFDAVMRVRTSTGIRAVDFFGAFYMSNTTDV 778

Query: 950  SLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRIRVHTLCLPVVSSLADV 1009
             LA ++ D    V+   ++ L + S    Q ALLYTS  G+RR+R+H L L   + LAD+
Sbjct: 779  ELAGLDGDKTVTVEFKHDDRLNEESGALLQCALLYTSCAGQRRLRIHNLALNCCTQLADL 838

Query: 1010 YAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSA-LMAP 1068
            Y   +    I  +A  A    ++S +   RD L+      L+ Y    ++   +  L+ P
Sbjct: 839  YRNCETDTLINYMAKFAYRGVLNSPVKAVRDTLITQCAQILACYRKNCASPSSAGQLILP 898

Query: 1069 SSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLT 1128
              +KL P+Y+  +LK    + G     DDR Y    + S  +       +P L  + +  
Sbjct: 899  ECMKLLPVYLNCVLKSDVLQPGAEVTTDDRAYVRQLVTSMDVTETNVFFYPRLLPLTKSP 958

Query: 1129 DEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIEDVLGYTN 1188
             E           +PP  + S E+L+    +L++ G   ++WVG       ++ +   ++
Sbjct: 959  VESTT--------EPPAVRASEERLSNGDIYLLENGLNLFLWVGASVQQGVVQSLFSVSS 1010

Query: 1189 FASIPQKMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKDESPAKAEFFQHLIEDR 1248
            F+ I   ++ LP LD   S++ R  I  LR  R     L +VK E   +  F   L+ED+
Sbjct: 1011 FSQITSGLSVLPVLDNPLSKKVRGLIDSLRAQRSRYMKLTVVKQEDKMEMLFKHFLVEDK 1070

Query: 1249 T-EAAFSYYEFLLHVQQQI 1266
            +     SY +FL H+ ++I
Sbjct: 1071 SLSGGASYVDFLCHMHKEI 1089



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 78/289 (26%), Positives = 95/289 (32%), Gaps = 66/289 (22%)

Query: 4   PAGSSHPAASARIPPKFGGAAVSGAAAPAGP-GA--GPAPHQQNGPAQNQMQVPSGYGLH 60
           P G   P         +GG   SG+ APA P GA  GP P  Q  P Q   + P   G  
Sbjct: 12  PFGQPQPIYPGYHQSSYGGQ--SGSTAPAIPYGAYNGPVPGYQQTPPQGMSRAPPSSG-- 67

Query: 61  HQNYIAPSGHYSQGPGKMTSLPLDTQCGD-YYSALYTVPTQNVTPNTVNQQ--PGAQQ-- 115
                AP    +Q P           CG   Y        QN   +TV  Q  PG+Q   
Sbjct: 68  -----APPASTAQAP-----------CGQAAYGQFGQGDVQNGPSSTVQMQRLPGSQPFG 111

Query: 116 ------------LYSRGPP------APHIVGSTLGSFQGAASSASHL----HTSASQPYS 153
                       L   GPP      A  + G  +      A  +S L     TS +    
Sbjct: 112 SPLAPVGNQPPVLQPYGPPPTSAQVATQLSGMQISGAVAPAPPSSGLGFGPPTSLASASG 171

Query: 154 SFVNH--YNSPAMYSASSSVASQGFP--STCGHYAMSTVSNAAYPSVSYPSLPA------ 203
           SF N   Y S     A     +QG P   T    A S  S+   P+   P LP+      
Sbjct: 172 SFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTGPLL 231

Query: 204 -GDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQ 251
            G ++G    SQ      P +      Q T      PL PLP     QQ
Sbjct: 232 PGQSFGGPSVSQPNHVSSPPQALPPGTQMT-----GPLGPLPPMHSPQQ 275


>gi|190343021 Sec24-related protein D [Homo sapiens]
          Length = 1032

 Score =  395 bits (1014), Expect = e-109
 Identities = 289/997 (28%), Positives = 470/997 (47%), Gaps = 85/997 (8%)

Query: 320  GSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDE 379
            G +G+ +T  PP       PV +V             +  Y  +  SS P P+S++S  +
Sbjct: 70   GQNGAHATGHPPQRFPGPPPVNNVAS----------SHAPYQPSAQSSYPGPISTSSVTQ 119

Query: 380  EEEE---------------EDEEAGVDSSSTTSSASPMPNSYDALEGGSY-----PDMLS 419
               +                 +      S+T+    P P     L+ GS      P  L+
Sbjct: 120  LGSQLSAMQINSYGSGMAPPSQGPPGPLSATSLQTPPRPPQPSILQPGSQVLPPPPTTLN 179

Query: 420  SSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLIS 479
               +SP P P   PD  S P P +A     P P +     G GYP  Q      + P ++
Sbjct: 180  GPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQT---LGAGYPPQQAN----SGPQMA 232

Query: 480  GVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQP-ESLRP-----VNLTQERNI 533
            G Q S P   GF   P Q  G  Q    +   S+ S  Q  E+ R      V  T  R  
Sbjct: 233  GAQLSYP--GGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIENDRASRGGQVYATNTRGQ 290

Query: 534  LPMTPVWAPVPNLNADLKKL-NCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDL- 591
            +P      P+   +  ++   N SP   RCT    P T  +  +A++PL  ++ PF  + 
Sbjct: 291  IP------PLVTTDCMIQDQGNASPRFIRCTTYCFPCTSDMAKQAQIPLAAVIKPFATIP 344

Query: 592  -TQLPVITSNT----IVRCRSCRTYINPFVSFIDQ-RRWKCNLCYRVNDVPEEFMYNPLT 645
              + P+   N      VRC  C+ Y+ PF+ FI+  RR++C  C  VNDVP  F +  L 
Sbjct: 345  SNESPLYLVNHGESGPVRCNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPP-FYFQHLD 403

Query: 646  RSYG--EPHKRPEVQNSTVEFIASSDYMLR--PPQPAVYLFVLDVSHNAVEAGYLTILCQ 701
                  + +++PE+   + E++A+ DY  +  PP P  ++F++DVS++ ++ G + ++C+
Sbjct: 404  HIGRRLDHYEKPELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLICE 463

Query: 702  SLLENLDKLPGD-----SRTRIGFMTFDSTIHFYNLQEGLSQPQMLIVSDIDDVFLPTPD 756
             L   L+K+P +     S  R+GF+T++  +HF+N++  L+QPQM++V+D+ +VF+P  D
Sbjct: 464  ELKTMLEKIPKEEQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVTDVGEVFVPLLD 523

Query: 757  SLLVNLYESKELIKDLLNALPNMFTNTRETHSALGPALQAAFKLMSPTG--GRVSVFQTQ 814
              LVN  ES+ +I +LL+ +P+MF ++ E  +   P +QA  + +      G++ +F + 
Sbjct: 524  GFLVNYQESQSVIHNLLDQIPDMFADSNENETVFAPVIQAGMEALKAADCPGKLFIFHSS 583

Query: 815  LPSLGA-GLLQSREDPNQRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSD 873
            LP+  A G L++R+D    ++ K      P T+ Y  LA DC     +V LFL  SQY D
Sbjct: 584  LPTAEAPGKLKNRDDKKLVNTDKEKILFQPQTNVYDSLAKDCVAHGCSVTLFLFPSQYVD 643

Query: 874  LASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRIRCTKGLS 933
            +ASL  + + + G +Y Y +F    +  Q      DL+  + +KIGF+A+MR+R + G  
Sbjct: 644  VASLGLVPQLTGGTLYKYNNFQMHLDRQQ---FLNDLRNDIEKKIGFDAIMRVRTSTGFR 700

Query: 934  MHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLVCFQTALLYTSSKGERRI 993
               F G   + +T  + +A I+ D    V+   ++ L++ S    Q A+LYT+  G+RR+
Sbjct: 701  ATDFFGGILMNNTTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRL 760

Query: 994  RVHTLCLPVVSSLADVYAGVDVQAAICLLANMAVDRSVSSSLSDARDALVNAVVDSLSAY 1053
            R+H L L   S LAD+Y   +  A I   A  A    +   L   R+ LVN     L+ Y
Sbjct: 761  RIHNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQTAHMLACY 820

Query: 1054 -GSTVSNLQHSALMAPSSLKLFPLYVLALLKQKAFRTGTSTRLDDRVYAMCQIKSQPLVH 1112
              +  S    S L+ P S+K+ P+Y+  LLK     +      D+R Y    + +  +  
Sbjct: 821  RKNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEISTDERAYQRQLVMTMGVAD 880

Query: 1113 LMKMIHPNLYRIDRLTDEGAVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVG 1172
                 +P L  I  L  +  +         P   + S  +L+ EG FL+  G   ++W+G
Sbjct: 881  SQLFFYPQLLPIHTLDVKSTM--------LPAAVRCSESRLSEEGIFLLANGLHMFLWLG 932

Query: 1173 KGCDNNFIEDVLGYTNFASIPQKMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVKD 1232
                   I+ +    +FA I   MT LPE+    S++ R  +  ++  RP S  L IVK 
Sbjct: 933  VSSPPELIQGIFNVPSFAHINTDMTLLPEVGNPYSQQLRMIMGIIQQKRPYSMKLTIVKQ 992

Query: 1233 ESPAKAEFFQHLIEDR-TEAAFSYYEFLLHVQQQICK 1268
                +  F Q L+ED+      SY +FL  V ++IC+
Sbjct: 993  REQPEMVFRQFLVEDKGLYGGSSYVDFLCCVHKEICQ 1029



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 52/245 (21%), Positives = 77/245 (31%), Gaps = 30/245 (12%)

Query: 4   PAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQN 63
           P+ ++ P    +     G  A  G   P  P  GP    QNG            G    N
Sbjct: 32  PSHTASPTGMMKPAGPLGATATRGMLPPGPPPPGPHQFGQNGAHATGHPPQRFPGPPPVN 91

Query: 64  YIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPA 123
            +A S H    P   +S P     G   ++  T     ++   +N         S+GPP 
Sbjct: 92  NVA-SSHAPYQPSAQSSYP-----GPISTSSVTQLGSQLSAMQINSYGSGMAPPSQGPPG 145

Query: 124 PHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHY 183
           P               SA+ L T    P  S +   +       ++       P     Y
Sbjct: 146 P--------------LSATSLQTPPRPPQPSILQPGSQVLPPPPTTLNGPGASPLPLPMY 191

Query: 184 AMSTVSNAAYPSVSY--PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLP 241
               +S    P+  Y  P LP G T G  +  Q A       ++        +S+P   P
Sbjct: 192 RPDGLSGPPPPNAQYQPPPLP-GQTLGAGYPPQQA-------NSGPQMAGAQLSYPGGFP 243

Query: 242 PLPSQ 246
             P+Q
Sbjct: 244 GGPAQ 248


>gi|14591924 Sec23 homolog B [Homo sapiens]
          Length = 767

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 132/637 (20%), Positives = 239/637 (37%), Gaps = 97/637 (15%)

Query: 558  DSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCR-SCRTYINPFV 616
            D  R +    P ++    +  +PL  LL P ++   LP +    ++  R +C+  +NP  
Sbjct: 15   DGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLC 74

Query: 617  SFIDQRR--WKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEV--QNSTVEFIASSDYML 672
              +D R   W CN C++ N  P      P      E ++  E+  Q ST+E++       
Sbjct: 75   Q-VDYRAKLWACNFCFQRNQFP------PAYGGISEVNQPAELMPQFSTIEYVIQRG--- 124

Query: 673  RPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNL 732
                P ++L+V+D     +E   L  L +SL  +L  LP D+   +G +TF   +  + L
Sbjct: 125  -AQSPLIFLYVVD---TCLEEDDLQALKESLQMSLSLLPPDA--LVGLITFGRMVQVHEL 178

Query: 733  Q-EGLSQPQM------LIVSDIDDVFLPTPDSL--------------------LVNLYES 765
              EG+S+  +      L    I D+   T  ++                    L  +++ 
Sbjct: 179  SCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKI 238

Query: 766  KELIKDLLNAL---PNMFTNTRETHSALGPALQAAFKLMS----PTGGRVSVFQTQLPSL 818
               + DLL  L   P   T  +    + G AL  A  L+      TG R+ +F    P+ 
Sbjct: 239  DMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQ 298

Query: 819  GAGLLQSREDPNQRSSTKVVQ-----HLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSD 873
            G G++   E      S   ++      +  AT  Y+ LA   +     +D++  +   + 
Sbjct: 299  GPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTG 358

Query: 874  LASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTR------KIGFEAVMRIR 927
            L  + C +  + G +    SF+           ++  +R  T+      ++ F A + ++
Sbjct: 359  LLEMKCCANLTGGYMVMGDSFN-------TSLFKQTFQRIFTKDFNGDFRMAFGATLDVK 411

Query: 928  CTKGLSMHTFHG---------------NFFVRSTDLLSLANINPDAGFAVQLSI----EE 968
             ++ L +    G                  V  T    +  ++P +   +   +      
Sbjct: 412  TSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNT 471

Query: 969  SLTDTSLVCFQTALLYTSSKGERRIRVHTLC---LPVVSSLADVYAGVDVQAAICLLANM 1025
             +        Q    Y  S  +RRIRV T+      V S L  + A  D +AA  L+A +
Sbjct: 472  PIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARL 531

Query: 1026 AVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQK 1085
             V R+ S    D    L   ++     +G   +    ++     S  L+P ++   L++ 
Sbjct: 532  GVFRAESEEGPDVLRWLDRQLIRLCQKFGQ-YNKEDPTSFRLSDSFSLYPQFMFH-LRRS 589

Query: 1086 AFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLY 1122
             F    +   D+  Y       Q L   + MI P LY
Sbjct: 590  PFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILY 626


>gi|14591926 Sec23 homolog B [Homo sapiens]
          Length = 767

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 132/637 (20%), Positives = 239/637 (37%), Gaps = 97/637 (15%)

Query: 558  DSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCR-SCRTYINPFV 616
            D  R +    P ++    +  +PL  LL P ++   LP +    ++  R +C+  +NP  
Sbjct: 15   DGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLC 74

Query: 617  SFIDQRR--WKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEV--QNSTVEFIASSDYML 672
              +D R   W CN C++ N  P      P      E ++  E+  Q ST+E++       
Sbjct: 75   Q-VDYRAKLWACNFCFQRNQFP------PAYGGISEVNQPAELMPQFSTIEYVIQRG--- 124

Query: 673  RPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNL 732
                P ++L+V+D     +E   L  L +SL  +L  LP D+   +G +TF   +  + L
Sbjct: 125  -AQSPLIFLYVVD---TCLEEDDLQALKESLQMSLSLLPPDA--LVGLITFGRMVQVHEL 178

Query: 733  Q-EGLSQPQM------LIVSDIDDVFLPTPDSL--------------------LVNLYES 765
              EG+S+  +      L    I D+   T  ++                    L  +++ 
Sbjct: 179  SCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKI 238

Query: 766  KELIKDLLNAL---PNMFTNTRETHSALGPALQAAFKLMS----PTGGRVSVFQTQLPSL 818
               + DLL  L   P   T  +    + G AL  A  L+      TG R+ +F    P+ 
Sbjct: 239  DMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQ 298

Query: 819  GAGLLQSREDPNQRSSTKVVQ-----HLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSD 873
            G G++   E      S   ++      +  AT  Y+ LA   +     +D++  +   + 
Sbjct: 299  GPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTG 358

Query: 874  LASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTR------KIGFEAVMRIR 927
            L  + C +  + G +    SF+           ++  +R  T+      ++ F A + ++
Sbjct: 359  LLEMKCCANLTGGYMVMGDSFN-------TSLFKQTFQRIFTKDFNGDFRMAFGATLDVK 411

Query: 928  CTKGLSMHTFHG---------------NFFVRSTDLLSLANINPDAGFAVQLSI----EE 968
             ++ L +    G                  V  T    +  ++P +   +   +      
Sbjct: 412  TSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNT 471

Query: 969  SLTDTSLVCFQTALLYTSSKGERRIRVHTLC---LPVVSSLADVYAGVDVQAAICLLANM 1025
             +        Q    Y  S  +RRIRV T+      V S L  + A  D +AA  L+A +
Sbjct: 472  PIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARL 531

Query: 1026 AVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQK 1085
             V R+ S    D    L   ++     +G   +    ++     S  L+P ++   L++ 
Sbjct: 532  GVFRAESEEGPDVLRWLDRQLIRLCQKFGQ-YNKEDPTSFRLSDSFSLYPQFMFH-LRRS 589

Query: 1086 AFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLY 1122
             F    +   D+  Y       Q L   + MI P LY
Sbjct: 590  PFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILY 626


>gi|14591928 Sec23 homolog B [Homo sapiens]
          Length = 767

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 132/637 (20%), Positives = 239/637 (37%), Gaps = 97/637 (15%)

Query: 558  DSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCR-SCRTYINPFV 616
            D  R +    P ++    +  +PL  LL P ++   LP +    ++  R +C+  +NP  
Sbjct: 15   DGVRFSWNVWPSSRLEATRMVVPLACLLTPLKERPDLPPVQYEPVLCSRPTCKAVLNPLC 74

Query: 617  SFIDQRR--WKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEV--QNSTVEFIASSDYML 672
              +D R   W CN C++ N  P      P      E ++  E+  Q ST+E++       
Sbjct: 75   Q-VDYRAKLWACNFCFQRNQFP------PAYGGISEVNQPAELMPQFSTIEYVIQRG--- 124

Query: 673  RPPQPAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYNL 732
                P ++L+V+D     +E   L  L +SL  +L  LP D+   +G +TF   +  + L
Sbjct: 125  -AQSPLIFLYVVD---TCLEEDDLQALKESLQMSLSLLPPDA--LVGLITFGRMVQVHEL 178

Query: 733  Q-EGLSQPQM------LIVSDIDDVFLPTPDSL--------------------LVNLYES 765
              EG+S+  +      L    I D+   T  ++                    L  +++ 
Sbjct: 179  SCEGISKSYVFRGTKDLTAKQIQDMLGLTKPAMPMQQARPAQPQEHPFASSRFLQPVHKI 238

Query: 766  KELIKDLLNAL---PNMFTNTRETHSALGPALQAAFKLMS----PTGGRVSVFQTQLPSL 818
               + DLL  L   P   T  +    + G AL  A  L+      TG R+ +F    P+ 
Sbjct: 239  DMNLTDLLGELQRDPWPVTQGKRPLRSTGVALSIAVGLLEGTFPNTGARIMLFTGGPPTQ 298

Query: 819  GAGLLQSREDPNQRSSTKVVQ-----HLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSD 873
            G G++   E      S   ++      +  AT  Y+ LA   +     +D++  +   + 
Sbjct: 299  GPGMVVGDELKIPIRSWHDIEKDNARFMKKATKHYEMLANRTAANGHCIDIYACALDQTG 358

Query: 874  LASLACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTR------KIGFEAVMRIR 927
            L  + C +  + G +    SF+           ++  +R  T+      ++ F A + ++
Sbjct: 359  LLEMKCCANLTGGYMVMGDSFN-------TSLFKQTFQRIFTKDFNGDFRMAFGATLDVK 411

Query: 928  CTKGLSMHTFHG---------------NFFVRSTDLLSLANINPDAGFAVQLSI----EE 968
             ++ L +    G                  V  T    +  ++P +   +   +      
Sbjct: 412  TSRELKIAGAIGPCVSLNVKGPCVSENELGVGGTSQWKICGLDPTSTLGIYFEVVNQHNT 471

Query: 969  SLTDTSLVCFQTALLYTSSKGERRIRVHTLC---LPVVSSLADVYAGVDVQAAICLLANM 1025
             +        Q    Y  S  +RRIRV T+      V S L  + A  D +AA  L+A +
Sbjct: 472  PIPQGGRGAIQFVTHYQHSSTQRRIRVTTIARNWADVQSQLRHIEAAFDQEAAAVLMARL 531

Query: 1026 AVDRSVSSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQK 1085
             V R+ S    D    L   ++     +G   +    ++     S  L+P ++   L++ 
Sbjct: 532  GVFRAESEEGPDVLRWLDRQLIRLCQKFGQ-YNKEDPTSFRLSDSFSLYPQFMFH-LRRS 589

Query: 1086 AFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLY 1122
             F    +   D+  Y       Q L   + MI P LY
Sbjct: 590  PFLQVFNNSPDESSYYRHHFARQDLTQSLIMIQPILY 626


>gi|38202214 SEC23-related protein A [Homo sapiens]
          Length = 765

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 129/631 (20%), Positives = 243/631 (38%), Gaps = 87/631 (13%)

Query: 558  DSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCRS-CRTYINPFV 616
            D  R +    P ++    +  +P+  L  P ++   LP I    ++  R+ CR  +NP  
Sbjct: 15   DGVRFSWNVWPSSRLEATRMVVPVAALFTPLKERPDLPPIQYEPVLCSRTTCRAVLNPLC 74

Query: 617  SFIDQRR--WKCNLCYRVNDVPEEFMYNPLTRSYGEPHKRPEV--QNSTVEFIASSDYML 672
              +D R   W CN CY+ N  P      P      E ++  E+  Q S++E++     +L
Sbjct: 75   Q-VDYRAKLWACNFCYQRNQFP------PSYAGISELNQPAELLPQFSSIEYV-----VL 122

Query: 673  RPPQ-PAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDSTIHFYN 731
            R PQ P ++L+V+D     +E   L  L +S+  +L  LP      +G +TF   +  + 
Sbjct: 123  RGPQMPLIFLYVVD---TCMEDEDLQALKESMQMSLSLLP--PTALVGLITFGRMVQVHE 177

Query: 732  LQ-EGLSQ---------------PQMLIVSDI--------DDVFLPTPDSLLVNLYESKE 767
            L  EG+S+                +ML +S +          V  P P +  +   +  +
Sbjct: 178  LGCEGISKSYVFRGTKDLSAKQLQEMLGLSKVPLTQATRGPQVQQPPPSNRFLQPVQKID 237

Query: 768  L-IKDLLNAL---PNMFTNTRETHSALGPALQAAFKLMS----PTGGRVSVFQTQLPSLG 819
            + + DLL  L   P      +    + G AL  A  L+      TG R+ +F     + G
Sbjct: 238  MNLTDLLGELQRDPWPVPQGKRPLRSSGVALSIAVGLLECTFPNTGARIMMFIGGPATQG 297

Query: 820  AGLLQSREDPNQRSSTKVV-----QHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDL 874
             G++   E      S   +     +++   T  ++ LA   +     +D++  +   + L
Sbjct: 298  PGMVVGDELKTPIRSWHDIDKDNAKYVKKGTKHFEALANRAATTGHVIDIYACALDQTGL 357

Query: 875  ASLACMSKYSAGCIYYYPSFHYTHNPSQAEKL-QKDLKRYLTRKIGFEAVMRIRCTKGLS 933
              + C    + G +    SF+ +      +++  KD+      K+GF   + I+ ++ + 
Sbjct: 358  LEMKCCPNLTGGYMVMGDSFNTSLFKQTFQRVFTKDMHGQF--KMGFGGTLEIKTSREIK 415

Query: 934  MHTFHG---------------NFFVRSTDLLSLANINPDAGFAVQLSI----EESLTDTS 974
            +    G                     T    +  ++P    A+   +       +    
Sbjct: 416  ISGAIGPCVSLNSKGPCVSENEIGTGGTCQWKICGLSPTTTLAIYFEVVNQHNAPIPQGG 475

Query: 975  LVCFQTALLYTSSKGERRIRVHTLC---LPVVSSLADVYAGVDVQAAICLLANMAVDRSV 1031
                Q    Y  S G+RRIRV T+        + + ++ A  D +AA  L+A +A+ R+ 
Sbjct: 476  RGAIQFVTQYQHSSGQRRIRVTTIARNWADAQTQIQNIAASFDQEAAAILMARLAIYRAE 535

Query: 1032 SSSLSDARDALVNAVVDSLSAYGSTVSNLQHSALMAPSSLKLFPLYVLALLKQKAFRTGT 1091
            +    D    L   ++     +G    +   S+     +  L+P ++   L++ +F    
Sbjct: 536  TEEGPDVLRWLDRQLIRLCQKFGEYHKD-DPSSFRFSETFSLYPQFMFH-LRRSSFLQVF 593

Query: 1092 STRLDDRVYAMCQIKSQPLVHLMKMIHPNLY 1122
            +   D+  Y       Q L   + MI P LY
Sbjct: 594  NNSPDESSYYRHHFMRQDLTQSLIMIQPILY 624


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 115/468 (24%), Positives = 177/468 (37%), Gaps = 53/468 (11%)

Query: 10   PAAS--ARIPPKFGGAA-VSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIA 66
            PAA+  +RIP     A  ++ A  PA P A      +   A   M + S      +  +A
Sbjct: 2224 PAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASP-----RTAVA 2278

Query: 67   PSGHYSQGPGKMTSLPLDTQCGDYYSALYTVP-TQNVTPNTVNQQPGAQQLYSRGPPAP- 124
            PS      P   T+  ++       +AL  +  T + TP T    P +    SR P AP 
Sbjct: 2279 PSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSS----SRTPQAPA 2334

Query: 125  --HIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSA---SSSVASQGFPST 179
              ++VG          + A     +A  P +S  +   +PA+  A   S  V    +   
Sbjct: 2335 SANLVGPRSAHATAPVNIAGSRTAAALAP-ASLTSARMAPALSGANLTSPRVPLSAYERV 2393

Query: 180  CGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSP 239
             G  +   +  A   S + PS P+        TS+ AP+       + S      +   P
Sbjct: 2394 SGRTSPPLLDRAR--SRTPPSAPSQSR----MTSERAPSPSSRMGQAPSQSLLPPAQDQP 2447

Query: 240  LPPLPSQQHHQQQSLSGYSTLTWSSPGLPS----TQDNLIRNHTGSLAV---------AN 286
              P+PS    Q + L   +T    S  L S    T  +   +H G L+V           
Sbjct: 2448 RSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVG 2507

Query: 287  NNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQP 346
              P  T A   S   +  +QP K     S+  S SS SSS+ +  +++      +S ++ 
Sbjct: 2508 EPPASTGAQQPSA--LAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEG 2565

Query: 347  SELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEE-------EEDEEAGVDSSSTTSSA 399
            S L  Q  V     +    S  P P  +  +    E            +   SSS++SS+
Sbjct: 2566 SSLPVQPEVA----LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621

Query: 400  SPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAP 447
            S   +S  +    S     SSS+SS +P PA +P P + P PAS   P
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA-KPGPQALPKPASPKKP 2668



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 47/196 (23%), Positives = 71/196 (36%), Gaps = 29/196 (14%)

Query: 365 ASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASS 424
           A  +P+P S      E +    E G  S+   SS    P +        Y D        
Sbjct: 292 AGRSPSPASGRRG--EGDAPFSEPGTTSTQRPSS----PETATKQPSSPYEDKDKDKKEK 345

Query: 425 PAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLI-SGVQP 483
            A  P+P P+ +S     + P P  P P    +  G   P        AT PL    V P
Sbjct: 346 SATRPSPSPERSS-----TGPEPPAPTPLLAERHGGSPQPL-------ATTPLSQEPVNP 393

Query: 484 SNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPV 543
            +       + P + P     SSS       S   P S +P  +++  +  P +P  AP 
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSS-------SESSPPSPQPTKVSRHASSSPESPKPAPA 446

Query: 544 PNLNADLKKLNCSPDS 559
           P  +   ++++ SP S
Sbjct: 447 PGSH---REISSSPTS 459



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 130/601 (21%), Positives = 216/601 (35%), Gaps = 126/601 (20%)

Query: 5    AGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNY 64
            +GSS P A +R PP+    + S ++ P    +     Q +  +    +V SG      + 
Sbjct: 799  SGSSQPKAKSRTPPR---RSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSI 855

Query: 65   IAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPP-- 122
             +P  +      + +  P    C +           +  P   ++ P         PP  
Sbjct: 856  TSPQAN------EQSVTPQRRSCFE----------SSPDPELKSRTPSRHSCSGSSPPRV 899

Query: 123  --------APHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQ 174
                    +P    S     +   S     H+ +S P  S V    +P     S SV   
Sbjct: 900  KSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP---RRSRSV--- 953

Query: 175  GFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAI 234
               S C     S V +   P  S+    + DT       +  P   P + +S S      
Sbjct: 954  ---SPC-----SNVESRLLPRYSHSGSSSPDT-------KVKPETPPRQSHSGS------ 992

Query: 235  SHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVA 294
               SP P + +Q      SLSG    + S      ++D+L+++  GSL++          
Sbjct: 993  --ISPYPKVKAQT-PPGPSLSG----SKSPCPQEKSKDSLVQSCPGSLSL---------- 1035

Query: 295  DSLSCPVMQNVQPPKSS--PVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQ 352
                C  +++  PP  S   V S  L G S +S      T++  V    S    S  LQ 
Sbjct: 1036 ----CAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHS---ESPSLQS 1088

Query: 353  KGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGG 412
            K     +   +++SS  T L+S S   ++  E       S    S  SP  + + + +  
Sbjct: 1089 KSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSA----SPMLKSGMSPEQSRFQS-DSS 1143

Query: 413  SYPDMLSSS---------ASSPAPDPAPEPDPASAPAPAS----APAPVV--PQPSKMAK 457
            SYP + S+S         A S      P  + A+A  P      +P PV   P+ S + K
Sbjct: 1144 SYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFK 1203

Query: 458  PFGYGYPTLQPG--------YQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIG 509
                  P  + G         QN+  P  S  +    V    ++   Q   ++ LSS + 
Sbjct: 1204 DTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQI--LSHLSSELK 1261

Query: 510  GLS---LQSSPQPESLRPVNLTQERN----------ILPMTPVWAPVPNLNADLKKLNCS 556
             +S    +SSP+ E    V+LT +++          +  M   W   P+ + + K+L+ S
Sbjct: 1262 EMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGG-PHFSPEHKELSNS 1320

Query: 557  P 557
            P
Sbjct: 1321 P 1321



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 63/257 (24%), Positives = 81/257 (31%), Gaps = 56/257 (21%)

Query: 189 SNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQH 248
           S  A+ S S  S  + DT      S  A T             TA++  SP P       
Sbjct: 257 SRRAHRSTSADSASSSDTSRSRSRSAAAKT-----------HTTALAGRSPSPA------ 299

Query: 249 HQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPP 308
                  G     +S PG  STQ         S   A   P+    D       ++   P
Sbjct: 300 ---SGRRGEGDAPFSEPGTTSTQ------RPSSPETATKQPSSPYEDKDKDKKEKSATRP 350

Query: 309 KSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSA 368
             SP            SST   P A  P+        P  L      Q  E VN  + ++
Sbjct: 351 SPSPE----------RSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQ--EPVNPPSEAS 398

Query: 369 PTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPD 428
           PT       D    +  E+    SSS +S  SP P              +S  ASS    
Sbjct: 399 PTR------DRSPPKSPEKLPQSSSSESSPPSPQPTK------------VSRHASSSPES 440

Query: 429 PAPEPDPASAPAPASAP 445
           P P P P S    +S+P
Sbjct: 441 PKPAPAPGSHREISSSP 457



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 59/248 (23%), Positives = 88/248 (35%), Gaps = 33/248 (13%)

Query: 231  NTAISHP--SPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNN 288
            N +IS P    +P  PS++       S  ++      GLP T     R+ +GS     + 
Sbjct: 1399 NQSISSPVLDAVPRTPSRER------SSSASSPEMKDGLPRTPSR--RSRSGSSPGLRDG 1450

Query: 289  PTITVADSLS--CPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTP-PTANHPVEPVTSVTQ 345
                   SLS   P M+++ P   S   S   S     +  +TP P +  P  P  +   
Sbjct: 1451 SGTPSRHSLSGSSPGMKDI-PRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKC 1509

Query: 346  PSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEED-------EEAGVDSSSTTSS 398
             +   ++ G    E   +Q + A TPL   S     +E D       +E     SS  S 
Sbjct: 1510 LTPQRERSG---SESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSK 1566

Query: 399  ASPMPNSYDALEGGSYPDM---------LSSSASSPAPDPAPEPDPASAPAPASAPAPVV 449
            A            GS P++          S S SSP     P   P +     S+P P  
Sbjct: 1567 AKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKA 1626

Query: 450  PQPSKMAK 457
            P P  + +
Sbjct: 1627 PAPRALPR 1634


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 67/308 (21%), Positives = 112/308 (36%), Gaps = 23/308 (7%)

Query: 199 PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYS 258
           P LP        F + + P   P K++S        +   P    PS    +  +L   +
Sbjct: 72  PKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST-KITTLPNVT 130

Query: 259 TLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVL 318
            L  ++  + S ++    +   +LA  N+        +   P      PP SS    T  
Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTA 190

Query: 319 SGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDD 378
           +  + S++T+ PP+++ P E   +   P                   ++ P P SS++  
Sbjct: 191 APPTPSATTQAPPSSSAPPETTAAPPTPP------------------ATTPAPPSSSAPP 232

Query: 379 EEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDP-AS 437
           E        +    +  +SSA P   +       +  D   SSAS+P    A  P P A+
Sbjct: 233 ETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLD--PSSASAPPETTAAPPTPSAT 290

Query: 438 APAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQ 497
            PAP S+PAP     + +  P      TL P     +A        S    +   + P  
Sbjct: 291 TPAPPSSPAPQETTAAPITTP-NSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTS 349

Query: 498 YPGVNQLS 505
            PG N++S
Sbjct: 350 APGQNKIS 357



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 32/148 (21%), Positives = 52/148 (35%), Gaps = 14/148 (9%)

Query: 10  PAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSG 69
           P+A+ + PP       + AA P  P   PAP   + P +     P+       +   P+ 
Sbjct: 195 PSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPT------PSATTPAP 248

Query: 70  HYSQGPGKMTSLP-------LD-TQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGP 121
             S  P + T++P       LD +            PT + T       P  Q+  +   
Sbjct: 249 LSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPI 308

Query: 122 PAPHIVGSTLGSFQGAASSASHLHTSAS 149
             P+   +TL       S+A    T+ S
Sbjct: 309 TTPNSSPTTLAPDTSETSAAPTHQTTTS 336


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 67/308 (21%), Positives = 112/308 (36%), Gaps = 23/308 (7%)

Query: 199 PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYS 258
           P LP        F + + P   P K++S        +   P    PS    +  +L   +
Sbjct: 72  PKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST-KITTLPNVT 130

Query: 259 TLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVL 318
            L  ++  + S ++    +   +LA  N+        +   P      PP SS    T  
Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTA 190

Query: 319 SGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDD 378
           +  + S++T+ PP+++ P E   +   P                   ++ P P SS++  
Sbjct: 191 APPTPSATTQAPPSSSAPPETTAAPPTPP------------------ATTPAPPSSSAPP 232

Query: 379 EEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDP-AS 437
           E        +    +  +SSA P   +       +  D   SSAS+P    A  P P A+
Sbjct: 233 ETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLD--PSSASAPPETTAAPPTPSAT 290

Query: 438 APAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQ 497
            PAP S+PAP     + +  P      TL P     +A        S    +   + P  
Sbjct: 291 TPAPPSSPAPQETTAAPITTP-NSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTS 349

Query: 498 YPGVNQLS 505
            PG N++S
Sbjct: 350 APGQNKIS 357



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 32/148 (21%), Positives = 52/148 (35%), Gaps = 14/148 (9%)

Query: 10  PAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSG 69
           P+A+ + PP       + AA P  P   PAP   + P +     P+       +   P+ 
Sbjct: 195 PSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPT------PSATTPAP 248

Query: 70  HYSQGPGKMTSLP-------LD-TQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGP 121
             S  P + T++P       LD +            PT + T       P  Q+  +   
Sbjct: 249 LSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPI 308

Query: 122 PAPHIVGSTLGSFQGAASSASHLHTSAS 149
             P+   +TL       S+A    T+ S
Sbjct: 309 TTPNSSPTTLAPDTSETSAAPTHQTTTS 336


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 67/308 (21%), Positives = 112/308 (36%), Gaps = 23/308 (7%)

Query: 199 PSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYS 258
           P LP        F + + P   P K++S        +   P    PS    +  +L   +
Sbjct: 72  PKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSAST-KITTLPNVT 130

Query: 259 TLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVL 318
            L  ++  + S ++    +   +LA  N+        +   P      PP SS    T  
Sbjct: 131 FLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTA 190

Query: 319 SGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDD 378
           +  + S++T+ PP+++ P E   +   P                   ++ P P SS++  
Sbjct: 191 APPTPSATTQAPPSSSAPPETTAAPPTPP------------------ATTPAPPSSSAPP 232

Query: 379 EEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDP-AS 437
           E        +    +  +SSA P   +       +  D   SSAS+P    A  P P A+
Sbjct: 233 ETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLD--PSSASAPPETTAAPPTPSAT 290

Query: 438 APAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQ 497
            PAP S+PAP     + +  P      TL P     +A        S    +   + P  
Sbjct: 291 TPAPPSSPAPQETTAAPITTP-NSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTS 349

Query: 498 YPGVNQLS 505
            PG N++S
Sbjct: 350 APGQNKIS 357



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 32/148 (21%), Positives = 52/148 (35%), Gaps = 14/148 (9%)

Query: 10  PAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSG 69
           P+A+ + PP       + AA P  P   PAP   + P +     P+       +   P+ 
Sbjct: 195 PSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPT------PSATTPAP 248

Query: 70  HYSQGPGKMTSLP-------LD-TQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGP 121
             S  P + T++P       LD +            PT + T       P  Q+  +   
Sbjct: 249 LSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPI 308

Query: 122 PAPHIVGSTLGSFQGAASSASHLHTSAS 149
             P+   +TL       S+A    T+ S
Sbjct: 309 TTPNSSPTTLAPDTSETSAAPTHQTTTS 336


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 95/430 (22%), Positives = 169/430 (39%), Gaps = 38/430 (8%)

Query: 67   PSGHYSQGPGKMTSLPLDTQ--CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG---P 121
            P+   S+G   +TS+P+ T        S L T P    TP T   Q  +    + G   P
Sbjct: 3272 PTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMP 3331

Query: 122  PAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCG 181
             + +  GST       + S + + +S +   S+     ++P   S  +S++    P+T  
Sbjct: 3332 TSTYSEGST--PLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLS----PTTAE 3385

Query: 182  HYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLP 241
              ++ T S+ +  +    S+P   T   + +  N  +  PV  N+    +T  S  SP  
Sbjct: 3386 GTSIPT-SSPSEGTTPLASMPVSTT-PVVSSEVNTLSTTPVDSNTLVTTSTEASS-SP-- 3440

Query: 242  PLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPV 301
                       +++  ++L  S+    ST  +++   T  +A +  +   T     S PV
Sbjct: 3441 -----------TIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPV 3489

Query: 302  MQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYV 361
              +  P  SSP  + V S  + ++   + P  N PV      +  +  L    V    +V
Sbjct: 3490 TTS-SPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFV 3548

Query: 362  --NNQASSAPTPLSST----SDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYP 415
              ++QASS+P  L  T    S   E         + S+  TSS +  P++       S P
Sbjct: 3549 TSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSV--DRSTP 3606

Query: 416  DMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATA 475
               S+ ++S    P     P S P+  S P  ++P  +        G  +  P   + + 
Sbjct: 3607 VTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLP--VDTST 3664

Query: 476  PLISGVQPSN 485
            P+I+  Q S+
Sbjct: 3665 PVITSTQVSS 3674



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 94/448 (20%), Positives = 154/448 (34%), Gaps = 57/448 (12%)

Query: 24   AVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPL 83
            +++   +P        P   N P     +V S      +    P+  YS+G   +TS+P+
Sbjct: 814  SITPVTSPEASTLSTTPVDSNSPVTTSTEVSSS-PTPAEGTSMPTSTYSEGRTPLTSMPV 872

Query: 84   DTQ--CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG------------PPAPHIVGS 129
             T        S L T P    TP T + +  +    S G             P   +  S
Sbjct: 873  STTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDS 932

Query: 130  TLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASS---SVASQG-FPSTCGHYAM 185
            T       A + S      S P ++     +SP     +S   S  S+G  P T    + 
Sbjct: 933  TTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSH 992

Query: 186  STVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPS 245
            + V+N+   ++S   +   D+   + TS  A +  P  + +    +T     +PL  +P 
Sbjct: 993  TLVANSEASTLSTTPV---DSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPV 1049

Query: 246  QQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPV---M 302
                   S +   + T +    P T        T S A +++    T AD  S P     
Sbjct: 1050 STTMVASSETSTLSTTPADTSTPVT--------TYSQASSSS----TTADGTSMPTSTYS 1097

Query: 303  QNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVN 362
            +   P  S PV + ++  S  S+ + TP   + PV   T  +      +   +       
Sbjct: 1098 EGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSE 1157

Query: 363  NQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSA 422
                 A  P+S+T              V S + T S +P+ +              S+ A
Sbjct: 1158 GTTPLASMPVSTT------------LVVSSEANTLSTTPVDSKTQV--------ATSTEA 1197

Query: 423  SSPAPDPAPEPDPASAPAPASAPAPVVP 450
            SSP P       P S P   S P   +P
Sbjct: 1198 SSPPPTAEVTSMPTSTPGERSTPLTSMP 1225



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 104/514 (20%), Positives = 179/514 (34%), Gaps = 48/514 (9%)

Query: 67   PSGHYSQGPGKMTSLPLDTQ--CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAP 124
            P+  YS+G   +TS+P+ T+       S L T P     P T + +  +    + G   P
Sbjct: 1092 PTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIP 1151

Query: 125  HIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYA 184
                S  G+   A+   S     +S+  +      +S    + S+  +S    +      
Sbjct: 1152 TSPPSE-GTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMP 1210

Query: 185  MSTVSNAAYPSVSYP--SLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPP 242
             ST    + P  S P    P   +     ++    T  PV  ++ +  +   +  + LP 
Sbjct: 1211 TSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPT 1270

Query: 243  LPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVAN---NNPTITVADSLSC 299
              + +     +    ST   +SP   ST      +  G +  +N   ++PT     S+  
Sbjct: 1271 STTSEGSTLLTSIPVSTTLVTSPE-ASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPT 1329

Query: 300  PVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGE 359
                  + P +S  V+T L  SS  S   T P  N      T VT  +E         G 
Sbjct: 1330 STYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNS-----TPVTTSTEACSSPTTSEGT 1384

Query: 360  YVNNQASSAPT------PLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGS 413
             + N   S  T      P+S+T     E        VD+S+  ++++   +S    EG S
Sbjct: 1385 SMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGIS 1444

Query: 414  YPDMLSSSASSPAPD-PAPEPDPASAPA------PASAPAPVVPQPSKMAKP-----FGY 461
             P    S   +P    P      A++ A      P  + +PVV   +  + P        
Sbjct: 1445 IPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSI 1504

Query: 462  GYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYP-------QQYPGVNQLSSSIGGLSLQ 514
               T   G    T+  +S    ++   +     P         Y   +   ++  G S+Q
Sbjct: 1505 AISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQ 1564

Query: 515  SSPQPESLRPVN---------LTQERNILPMTPV 539
            +S   E   P+          ++ E N L  TP+
Sbjct: 1565 TSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPI 1598



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 108/505 (21%), Positives = 180/505 (35%), Gaps = 79/505 (15%)

Query: 67  PSGHYSQGPGKMTSLPLDTQ--CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAP 124
           P    S+G   +TS+P  T          L T P +  TP T++ Q  +    + GP   
Sbjct: 207 PKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLS 266

Query: 125 HIV---GST------LGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQG 175
           +     GST      L      +S AS L T+   P ++ +    S    S+ ++     
Sbjct: 267 NSAPSGGSTPLTRMPLSVMLVVSSEASTLSTT---PAATNIPVITSTEASSSPTTAEGTS 323

Query: 176 FPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAIS 235
            P+       ST +  + P  S P+        +M T     ++ PV  ++     T  +
Sbjct: 324 IPT-------STYTEGSTPLTSTPASTMPVATSEMSTL----SITPVDTSTLV---TTST 369

Query: 236 HPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVAD 295
            PS LP           +LS  ST   + P       +   + T ++ V +     T ++
Sbjct: 370 EPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASE 429

Query: 296 SLSCPVM------------QNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSV 343
           + S P              +   P  S PV +T ++ S  S+ + TP      V+  T V
Sbjct: 430 ASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTP------VDSKTQV 483

Query: 344 TQPSELLQQKGVQYGEYVNNQASSAP----TPLSSTSDDEEEEEEDEEAGVDSSSTTSSA 399
           T  +E            VN+  +S P    TPL+S S         E       ++T S 
Sbjct: 484 TTSTEASSSPPTAE---VNSMPTSTPSEGSTPLTSMSVSTMPVASSE-------ASTLST 533

Query: 400 SPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPF 459
           +P+  S         P   SS ASS +  P     P S P+  S P   +P  +++    
Sbjct: 534 TPVDTST--------PVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSS 585

Query: 460 GYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQP 519
                +  P   N      S    S+    G       Y   ++  ++I  +S+ ++   
Sbjct: 586 EASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTY---SERGTTITSMSVSTT--- 639

Query: 520 ESLRPVNLTQERNILPMTPVWAPVP 544
                +  + E + L  TPV +  P
Sbjct: 640 -----LVASSEASTLSTTPVDSNTP 659



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 71/372 (19%), Positives = 134/372 (36%), Gaps = 30/372 (8%)

Query: 72  SQGPGKMTSLPLDT--QCGDYYSALYTVPTQNVT-----------PNTVNQQPGAQQLYS 118
           S+G   +T++P+ T        S   T+P  + T           P T      A    S
Sbjct: 389 SEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPS 448

Query: 119 RGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPS 178
            G  +  +    + +   A+S AS+L T+            +S    + S+  +S    +
Sbjct: 449 EG--STPLTSMPVSTTPVASSEASNLSTTP----------VDSKTQVTTSTEASSSPPTA 496

Query: 179 TCGHYAMSTVSNAAYP--SVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISH 236
                  ST S  + P  S+S  ++P   +     ++    T  PV  +S +  ++    
Sbjct: 497 EVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPE 556

Query: 237 PSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADS 296
            + +P     +     +    ST    S    +T      ++T     +  + + T A+ 
Sbjct: 557 GTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEG 616

Query: 297 LSCPVM---QNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQK 353
            S P     +      S  V +T+++ S  S+ + TP  +N PV   T  T  S   +  
Sbjct: 617 TSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGT 676

Query: 354 GVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGS 413
            +    Y          P+++T     E        VD+S+  ++++   +S    +G S
Sbjct: 677 SMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGAS 736

Query: 414 YPDMLSSSASSP 425
            P    S  S+P
Sbjct: 737 MPTSTPSEGSTP 748



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 83/397 (20%), Positives = 139/397 (35%), Gaps = 32/397 (8%)

Query: 72   SQGPGKMTSLPLDTQ--CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGS 129
            S+G   +TS+P+ T        ++L T P    TP T   Q       S  P        
Sbjct: 1510 SEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQA------SSSPTTADGTSM 1563

Query: 130  TLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVAS-QGFPSTCGHYAMSTV 188
               ++   ++  + L  S     SS  N  ++  + S +   AS +   ST    +  T+
Sbjct: 1564 QTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTI 1623

Query: 189  SNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVR--PVKDNSFSGQNTAISH-PSPLPPLPS 245
            S  +  S    S+P   T      S  A T+   PV  NS    +T +S  P+P      
Sbjct: 1624 STPSEGSPLLTSIPVSTT---PVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSM 1680

Query: 246  QQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVM--- 302
                  +  +  +++T  +  + S+  + +     +  V N+ P  T  ++ S P     
Sbjct: 1681 PTSTYTEGRTPLTSITVRTTPVASSAISTL----STTPVDNSTPVTTSTEARSSPTTSEG 1736

Query: 303  ---------QNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQK 353
                     +   P  S PV +T +  S  S+ + TP   + PV   T  T      +  
Sbjct: 1737 TSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGT 1796

Query: 354  GVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGS 413
             +              TP+S T     E        VDS+S   +++ + +S    EG S
Sbjct: 1797 SIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTS 1856

Query: 414  YPDMLSSSASSPAPD-PAPEPDPASAPAPASAPAPVV 449
                  S  S+     P      AS+     +  P V
Sbjct: 1857 IATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAV 1893



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 117/580 (20%), Positives = 196/580 (33%), Gaps = 59/580 (10%)

Query: 29   AAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQ-- 86
            A+P        P   N P     +V S      +    P+  Y++G   +TS+ + T   
Sbjct: 1644 ASPEASTLSTTPVDSNSPVITSTEVSSS-PTPAEGTSMPTSTYTEGRTPLTSITVRTTPV 1702

Query: 87   CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPH------------IVGSTLGSF 134
                 S L T P  N TP T + +  +    S G   P+            I  ST    
Sbjct: 1703 ASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVL 1762

Query: 135  QGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYP 194
               AS+ S      S P ++     +SP     +S                ST+S    P
Sbjct: 1763 SSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTS-------------IPTSTLSEGMTP 1809

Query: 195  SVSYP---SLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPP--------L 243
              S P   +L A      + T+       PV  NS    +TA+S  SP P          
Sbjct: 1810 LTSTPVSHTLVANSEASTLSTT-------PVDSNSPVVTSTAVSS-SPTPAEGTSIATST 1861

Query: 244  PSQQHHQQQSLS-GYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVM 302
            PS+      S+    +T+  S     ST   +      + A  +++PT     S+     
Sbjct: 1862 PSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTP 1921

Query: 303  QNVQPPKSS-PVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYV 361
            +  +PP +S PV +T ++ S  ++ + T      PV   +  +          +    Y 
Sbjct: 1922 REGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYS 1981

Query: 362  NNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSS 421
                     PLS+T     E        VD+S+  ++++   +S     G S      S 
Sbjct: 1982 EGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSE 2041

Query: 422  ASSP-APDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATA----- 475
             ++P A  P       S+     +  PV  +             T +      +A     
Sbjct: 2042 RTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGS 2101

Query: 476  PLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQP---ESLRPVNLTQERN 532
            PL++ +  S    +  +        V+  S  I    + SSP P    S++    +  R 
Sbjct: 2102 PLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRT 2161

Query: 533  ILPMTPVWAPVPNLNADLKKLNCSPDSFRCTLTNIPQTQA 572
             L   PV   V   +A +  L+ +P      +TN  + ++
Sbjct: 2162 PLTSMPVSTTVVASSA-ISTLSTTPVDTSTPVTNSTEARS 2200



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 127/604 (21%), Positives = 207/604 (34%), Gaps = 49/604 (8%)

Query: 29   AAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQ-- 86
            A+P        P   N P     ++ S      +    P+  YS+G   + S+P+ T+  
Sbjct: 2528 ASPEASTLSTTPVDSNSPVVTSTEISSS-ATSAEGTSMPTSTYSEGSTPLRSMPVSTKPL 2586

Query: 87   CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAP------------HIVGSTLGSF 134
                 S L T P     P T + +  +    ++    P             I+ ST+   
Sbjct: 2587 ASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVA 2646

Query: 135  QGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQ-GFPSTCGHYAMSTVSNAAY 193
               AS+ S          ++     +SP     SS   S  G  ST     + + +  A 
Sbjct: 2647 SSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLAN 2706

Query: 194  PSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPP-LPSQQHHQQQ 252
               S  S    DT   + TS  A +     + +    +T     +PL   L S       
Sbjct: 2707 SEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASS 2766

Query: 253  SLSGYST--LTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKS 310
              S  ST  +  S P   ST+ +         ++  + P+ T     S PV         
Sbjct: 2767 EASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSE 2826

Query: 311  SPVVSTVLSGSSGSSSTRT-----PPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQA 365
            +  +ST    +S   +T T     P TA   V P+++ ++ S LL    V      +++A
Sbjct: 2827 AGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEA 2886

Query: 366  SSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSS---A 422
            S+  T    TS       E       SS TT+  + MP S  +        +L S+   A
Sbjct: 2887 STLSTTPVDTSIPVTTSTEG-----SSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVA 2941

Query: 423  SSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQ 482
             S A   +  P     P   SA A   P  ++     G   P   PG +    PL S   
Sbjct: 2942 GSEASTLSTTPVDTRTPVTTSAEASSSPTTAE-----GTSMPISTPGERR--TPLTSMSV 2994

Query: 483  PSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNL---TQERNILPMTPV 539
             + PV S       + P     +S+    S ++S  P +     +   T      P+T +
Sbjct: 2995 STMPVASSEASTLSRTPAD---TSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSI 3051

Query: 540  -WAPVPNLNADLKKLNCSP---DSFRCTLTNIPQTQALLNKAKLPLGLLLHPFRDLTQLP 595
              +  P    +   L+ +P   +S   T T +  +        +P+         LT +P
Sbjct: 3052 PVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVP 3111

Query: 596  VITS 599
            V T+
Sbjct: 3112 VSTT 3115



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 97/504 (19%), Positives = 188/504 (37%), Gaps = 37/504 (7%)

Query: 67   PSGHYSQGPGKMTSLPLDTQ--CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAP 124
            P+  YS+G   +T++   T        S L T P    TP T + +       + G   P
Sbjct: 3331 PTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIP 3390

Query: 125  HIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYS---ASSSVASQGFPSTCG 181
                 T    +G    AS +  S +   SS VN  ++  + S    ++S  +   P+   
Sbjct: 3391 -----TSSPSEGTTPLAS-MPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAE 3444

Query: 182  HYAM--STVSNAAYPSVSYP--SLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHP 237
              ++  ST S  + P    P  + P   +     ++    T  PV  +S +  +   +  
Sbjct: 3445 GTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEV 3504

Query: 238  SPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSL 297
            + +P   + +     +    ST   +S    +     + ++T    V +++   +   +L
Sbjct: 3505 TSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNT---FVTSSSQASSSPATL 3561

Query: 298  SCPVMQNVQPPKSSPVVSTVLSGS----SGSSSTRTPPTANHPVEPVTSVTQPSELLQQK 353
                M+   P + S  ++T+L  S    S  +ST + P+ +      TS    S     +
Sbjct: 3562 QVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPE 3621

Query: 354  GVQYGEYVNNQASSAPT--PLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEG 411
             +       ++ S+  T  P+S+TS    E        VD+S+   +++ + +S    EG
Sbjct: 3622 VITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEG 3681

Query: 412  GSYPDMLSSSASSPAPDPAPEPD--PASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPG 469
             + P    S  S+P            +S  +  S P+ V   P   +        TL   
Sbjct: 3682 TTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDST 3741

Query: 470  YQNATAP----------LISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQP 519
              + + P          L+S    +    S     P  Y  ++  ++S G  S  ++ + 
Sbjct: 3742 TMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGS-SSPTTLEG 3800

Query: 520  ESLRPVNLTQERNILPMTPVWAPV 543
             +  P++ T ER+ L  T + +P+
Sbjct: 3801 TTTMPMSTTSERSTLLTTVLISPI 3824



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 116/554 (20%), Positives = 206/554 (37%), Gaps = 63/554 (11%)

Query: 72   SQGPGKMTSLPLDTQ--CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG---PPAPHI 126
            S+G   +TS+P+          S L T P  + +P T + +  +    + G   P + + 
Sbjct: 802  SEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYS 861

Query: 127  VGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAM- 185
             G T         S + + TSA    S+     ++P     ++S  ++  P+T    +M 
Sbjct: 862  EGRT--PLTSMPVSTTLVATSAISTLSTTPVDTSTPV----TNSTEARSSPTTSEGTSMP 915

Query: 186  -STVSNAAYPSVSYP--SLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPP 242
             ST    + P  S P  + P   +  +  ++    T  PV  ++ +  +   +  + +P 
Sbjct: 916  TSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPT 975

Query: 243  -LPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPV 301
              PS+         G + LT S+P   +   N   +   +  V +N P  T  ++ S P 
Sbjct: 976  STPSE---------GTTPLT-STPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPP 1025

Query: 302  ------MQNVQPPKSS------PVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSEL 349
                  M    P + S      PV +T+++ S  S+ + TP   + PV   +  +  S  
Sbjct: 1026 TAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTT 1085

Query: 350  LQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDAL 409
                 +    Y          P+S+      E        VD+S   ++++   +S    
Sbjct: 1086 ADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTA 1145

Query: 410  EGGSYPDMLSSSASSP-APDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQP 468
            EG S P    S  ++P A  P       S+ A   +  PV    SK          +  P
Sbjct: 1146 EGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPV---DSKTQVATSTEASSPPP 1202

Query: 469  GYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVNLT 528
              +  + P  +  + S P+ S     P ++  V    +S    +L +SP   S  PV  +
Sbjct: 1203 TAEVTSMPTSTPGERSTPLTS----MPVRHTPVASSEAS----TLSTSPVDTS-TPVTTS 1253

Query: 529  QERNILPMTPVWAPVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLPLGLLLHPF 588
             E +  P T     +P           +       LT+IP +  L+   +    LL  P 
Sbjct: 1254 AETSSSPTTAEGTSLP---------TSTTSEGSTLLTSIPVSTTLVTSPEAST-LLTTPV 1303

Query: 589  RDLTQLPVITSNTI 602
               T+ PV+TSN +
Sbjct: 1304 D--TKGPVVTSNEV 1315



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 89/433 (20%), Positives = 152/433 (35%), Gaps = 36/433 (8%)

Query: 72   SQGPGKMTSLPLDTQ--CGDYYSALYTVPTQN----VTPNTVNQQPGAQQ-------LYS 118
            S+G   +TS+P+ T        S L T P  +    VT   V+  P   +        YS
Sbjct: 3042 SEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYS 3101

Query: 119  RGP-PAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASS---SVASQ 174
             G  P   +  ST      A S+ S      S P ++    ++SP     +S   S  S+
Sbjct: 3102 EGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSE 3161

Query: 175  GFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAI 234
            G  +   +  +ST+   +    +  + P  DT   + TS  A +       S + + T+I
Sbjct: 3162 G-STPLTYMPVSTMLVVSSEDSTLSATPV-DTSTPVTTSTEATS-------STTAEGTSI 3212

Query: 235  SHPSP---LPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTI 291
               +P   + PL S         S  +++  ++P   +T        T S   +++ PT 
Sbjct: 3213 PTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP------LTTSTEASSSPPTA 3266

Query: 292  TVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQ 351
                  +    +   P  S PV +T ++ S  S+ + TP   + PV   +  +    +  
Sbjct: 3267 EGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIAD 3326

Query: 352  QKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEG 411
               +    Y            S+T     E        VD+S+  ++++    S    EG
Sbjct: 3327 GTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEG 3386

Query: 412  GSYPDMLSSSASSP-APDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGY 470
             S P    S  ++P A  P       S+     +  PV               PT+  G 
Sbjct: 3387 TSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGT 3446

Query: 471  QNATAPLISGVQP 483
               T+    G  P
Sbjct: 3447 SLPTSTTSEGSTP 3459



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 100/484 (20%), Positives = 177/484 (36%), Gaps = 24/484 (4%)

Query: 92   SALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQP 151
            S L T P    TP T + +  +    + G   P    S   +   +   ++ L TS  + 
Sbjct: 1237 STLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP-EA 1295

Query: 152  YSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYP---SLPAGDTYG 208
             +      ++      S+ V+S   P+       ST S    P  S P   +L A     
Sbjct: 1296 STLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAIS 1355

Query: 209  QMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPL-PSQQHHQQQSLSGYSTLTWSSPGL 267
             + T+       PV  ++ +  +   S  + +P   PS+      S+   +T   SS   
Sbjct: 1356 ILSTTP-VDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEAS 1414

Query: 268  PSTQDNLIRNHTGSL-AVANNNPTITVADSLSCPVM---QNVQPPKSSPVVSTVLSGSSG 323
              +   +  +  G+  A A ++PT   A+ +S P     +   P KS PV +T ++ S  
Sbjct: 1415 TLSATPVDTSTPGTTSAEATSSPT--TAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEA 1472

Query: 324  SSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPT--PLSSTSDDEEE 381
            S+ + TP  +N PV  VTS    S     +G        ++ S+A T  P+S+T+    E
Sbjct: 1473 STLSTTPVDSNSPV--VTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSE 1530

Query: 382  EEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPD-PAPEPDPASAPA 440
                      +S+  ++ S   +S    +G S      S  S+P    P       S+ A
Sbjct: 1531 INSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEA 1590

Query: 441  PASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNAT-----APLISGVQPSNPVYSGFQQYP 495
               +  P+  +    A        T +      +     +PL++ +  S    +  +   
Sbjct: 1591 NTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEAST 1650

Query: 496  QQYPGVNQLSSSIGGLSLQSSPQP-ESLRPVNLTQERNILPMTPVWA-PVPNLNADLKKL 553
                 V+  S  I    + SSP P E       T      P+T +     P  ++ +  L
Sbjct: 1651 LSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTL 1710

Query: 554  NCSP 557
            + +P
Sbjct: 1711 STTP 1714



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 62/290 (21%), Positives = 101/290 (34%), Gaps = 28/290 (9%)

Query: 283  AVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTV-LSGSSGSSSTRTPPTANHPVEPVT 341
            A A+++PT     S+        + P +S  VST+ ++ S  S+ +RTP   + PV   T
Sbjct: 2963 AEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTST 3022

Query: 342  SVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASP 401
              +      +  G+               P+S+T     E        VDS+S   +++ 
Sbjct: 3023 EASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTE 3082

Query: 402  MPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPA-------PASAPAPVVPQPSK 454
            + +S    EG S P    S  S+P         P ++ A       P     PV      
Sbjct: 3083 VSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEA 3142

Query: 455  MAKPF---GYGYPTLQPG-------YQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQL 504
             + P    G   PT  P        Y   +  L+   + S    +               
Sbjct: 3143 HSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEAT 3202

Query: 505  SSSIG-GLSLQSSPQPESLRPVN---------LTQERNILPMTPVWAPVP 544
            SS+   G S+ +S   E + P+           + E +IL  TPV +  P
Sbjct: 3203 SSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP 3252



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 109/563 (19%), Positives = 191/563 (33%), Gaps = 54/563 (9%)

Query: 72   SQGPGKMTSLPLDTQ--CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGP-------- 121
            S+G   +TS+PL T        S L T P  + +P   + +  +  + + G         
Sbjct: 2098 SEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYS 2157

Query: 122  ----PAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFP 177
                P   +  ST      A S+ S      S P ++     +SP     +S   S    
Sbjct: 2158 DRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSE 2217

Query: 178  STCGHYAM--STVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAIS 235
             +    +M  ST+      + +  + P  DT   + TS  A +     + +    +T   
Sbjct: 2218 GSTPFTSMPVSTMPVVTSEASTLSATPV-DTSTPVTTSTEATSSPTTAEGTSIPTSTLSE 2276

Query: 236  HPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVAD 295
              +PL  +P    H   + S  STL+       +T  +     T S   ++  PT   A+
Sbjct: 2277 GTTPLTSIPVS--HTLVANSEVSTLS-------TTPVDSNTPFTTSTEASSPPPT---AE 2324

Query: 296  SLSCPVMQNVQ---PPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQ 352
              S P   + +   P    PV +T+++    S+ + TP   + PV   +           
Sbjct: 2325 GTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADD 2384

Query: 353  KGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGG 412
              +    Y          P+S+      E        VD+S+  ++++   +S    EG 
Sbjct: 2385 TSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGT 2444

Query: 413  SYPDMLSSSASSPAPDPAPEPDP---------ASAPAPASAPAPVVPQPSK---MAKPFG 460
            S P    S  ++P         P         ++ P   S P     + S     A+   
Sbjct: 2445 SIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIV 2504

Query: 461  YGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYP--QQYPGVNQLSSSIGGLSLQSSPQ 518
                T   G    T+  +S    ++P  S     P     P V     S    S + +  
Sbjct: 2505 VPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSM 2564

Query: 519  PESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAK 578
            P S      T  R++    PV +  P  +++   L+ +P      +T   +T +    AK
Sbjct: 2565 PTSTYSEGSTPLRSM----PV-STKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAK 2619

Query: 579  ---LPLGLLLHPFRDLTQLPVIT 598
               +P+         LT + V T
Sbjct: 2620 DTSMPISTPSEVSTSLTSILVST 2642



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 120/506 (23%), Positives = 185/506 (36%), Gaps = 81/506 (16%)

Query: 67   PSGHYSQGPGKMTSLPLDTQ--CGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRG---P 121
            P+  YS+G   +TS+P+ T        S   T P    TP T + +  +    + G   P
Sbjct: 2388 PTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIP 2447

Query: 122  PAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCG 181
             +P   G+T         S + + +S +   S+     ++P   S  +S +    P+T  
Sbjct: 2448 TSPPSEGTT--PLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSS----PTTAE 2501

Query: 182  HYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTV--RPVKDNSFSGQNTAISHPSP 239
               +  +S A+  S    S+P   T      S  A T+   PV  NS    +T IS  + 
Sbjct: 2502 DIVV-PISTASEGSTLLTSIPVSTT---PVASPEASTLSTTPVDSNSPVVTSTEISSSA- 2556

Query: 240  LPPLPSQQHHQQQSLSGYS--TLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSL 297
                         S  G S  T T+S    P            S+ V+      + A +L
Sbjct: 2557 ------------TSAEGTSMPTSTYSEGSTP----------LRSMPVSTKPLASSEASTL 2594

Query: 298  SCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQY 357
            S   +       S PV ++  + SS +++  T    + P E  TS+T  S L+    V  
Sbjct: 2595 STTPVDT-----SIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLT--SILVSTMPV-- 2645

Query: 358  GEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDM 417
                   ASS  + LS+T  D          G  SS TT+  S MP S          ++
Sbjct: 2646 -------ASSEASTLSTTPVD-TRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNI 2697

Query: 418  LSSS---ASSPAPDPAPEPDPASAPAPASAPAPVVPQPS-----KMAKPFGYGYP----- 464
            L S+   A+S A   +  P   S P   SA A   P  +     +++ P     P     
Sbjct: 2698 LVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSIL 2757

Query: 465  --TLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESL 522
              TL      A+    + V  S PV +  +      P   +++S       ++S  P + 
Sbjct: 2758 VSTLPVASSEASTVSTTAVDTSIPVTTSTE--ASSSPTTAEVTSMPTSTPSETS-TPLTS 2814

Query: 523  RPVNLT----QERNILPMTPVWAPVP 544
             PVN T     E   L  TPV    P
Sbjct: 2815 MPVNHTPVASSEAGTLSTTPVDTSTP 2840



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 82/328 (25%), Positives = 122/328 (37%), Gaps = 60/328 (18%)

Query: 238 SPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRN--------HTGSLAVANNNP 289
           S LPP    Q   +Q LS  +   W   G  S  D L R          TGS A   N  
Sbjct: 17  SLLPP----QAAAEQDLS-VNRAVWDGGGCISQGDVLNRQCQQLSQHVRTGSAA---NTA 68

Query: 290 TITVADSLSCPVM--QNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQ-- 345
           T T + ++  P M       P+ + + S+V S + G SSTR  PT +      TS +   
Sbjct: 69  TGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTL 128

Query: 346 -PSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPN 404
            PS              + + +S+PT    T   +       E  + S+    S +P+P 
Sbjct: 129 FPS--------------STEDTSSPTTPEGT---DVPMSTPSEESISSTMAFVSTAPLP- 170

Query: 405 SYDALEGGSY------PDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKP 458
           S++A    +Y      P   S+ ASS    P     P S  +  S P   +P        
Sbjct: 171 SFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPA------- 223

Query: 459 FGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQ--QYPQQYPGVNQLSSSIGGLSLQSS 516
                 T++     A   L + V+ S PV    Q    P    G +  +S+  G S   +
Sbjct: 224 -----STMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLT 278

Query: 517 PQPESLRPVNLTQERNILPMTPVWAPVP 544
             P S+  V ++ E + L  TP    +P
Sbjct: 279 RMPLSVMLV-VSSEASTLSTTPAATNIP 305



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 76/382 (19%), Positives = 130/382 (34%), Gaps = 27/382 (7%)

Query: 83  LDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLY---SRGPPAPHIVGSTLGSFQGAAS 139
           L+ QC      + T    N    T +      ++Y   S  P    I  S      G +S
Sbjct: 48  LNRQCQQLSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSS 107

Query: 140 SASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPS---- 195
           +      + ++  ++  +  +S  ++ +S+   S           MST S  +  S    
Sbjct: 108 T----RMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAF 163

Query: 196 VSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLP-------PLPSQQH 248
           VS   LP+ + Y  +    +  T       + S   T  S   P         PL S   
Sbjct: 164 VSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPA 223

Query: 249 HQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPP 308
              +  S  +    ++P   ST   +        A A+++PT     SLS         P
Sbjct: 224 STMKVASSEAITLLTTPVEISTPVTIS-------AQASSSPTTAEGPSLSNSAPSGGSTP 276

Query: 309 KSSPVVSTVLSGSSGSSS-TRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASS 367
            +   +S +L  SS +S+ + TP   N PV   T  +      +   +    Y       
Sbjct: 277 LTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPL 336

Query: 368 APTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAP 427
             TP S+      E        VD+S+  ++++   +     E  S      S  S+P  
Sbjct: 337 TSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLT 396

Query: 428 D-PAPEPDPASAPAPASAPAPV 448
           + P      AS+ A  ++  PV
Sbjct: 397 NMPVSTILVASSEASTTSTIPV 418


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 141/589 (23%), Positives = 213/589 (36%), Gaps = 88/589 (14%)

Query: 3    APAGSSHPAASARIPPKF-GGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHH 61
            AP G S P A+ ++PP       V        P  G  P     PA      P   GL  
Sbjct: 1285 APTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPR----PPSSGLPA 1340

Query: 62   QNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGP 121
                 P+      PG++ +  L T       A   +PT  +       +P  + ++S   
Sbjct: 1341 VLNPRPT----LTPGRLPTPTLGT-------ARAPMPTPTLV------RPLLKLVHS--- 1380

Query: 122  PAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCG 181
            P+P +  S  G+     SS  H+ +S   P SS +   NS  + S  SS  S    S+  
Sbjct: 1381 PSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLP 1440

Query: 182  HYAMSTVSNAAYPSVSYP-SLPAG-DTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSP 239
                +T+   A   ++ P S P      G    +   P + PV   +    + A S  SP
Sbjct: 1441 ISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASP 1500

Query: 240  LPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSC 299
                 +       SLS  S+ T   P L +   + +     ++A A + P +  A +L+ 
Sbjct: 1501 SASALTLGLATAPSLS--SSQTPGHPLLLAPTSSHVPGLNSTVAPACS-PVLVPASALAS 1557

Query: 300  PVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSEL-----LQQKG 354
            P       P  +P  +++L+ +S +S     P A     P T++  PS       L    
Sbjct: 1558 PFPS---APNPAPAQASLLAPASSASQALATPLAPMAA-PQTAILAPSPAPPLAPLPVLA 1613

Query: 355  VQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSY 414
               G      +S  P P+ + S                 ++ +SASP+P     L   S 
Sbjct: 1614 PSPGAAPVLASSQTPVPVMAPSSTP-------------GTSLASASPVPAPTPVLAPSST 1660

Query: 415  PDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNAT 474
              ML      PAP P+P P PAS    A APA                 PTL     + T
Sbjct: 1661 QTML------PAPVPSPLPSPASTQTLALAPALA---------------PTLGGSSPSQT 1699

Query: 475  APLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSI--GGLSLQSSPQPESLRPVNLTQERN 532
              L +G  P  P       +P Q   +   SS +     +L  +P P    P+  TQ  +
Sbjct: 1700 LSLGTG-NPQGP-------FPTQTLSLTPASSLVPTPAQTLSLAPGP----PLGPTQTLS 1747

Query: 533  ILPMTPVWAPVPNLNADLKKLNCSPDSFRCTLTNIPQTQAL-LNKAKLP 580
            + P  P+    P   A    L  +P S   +L      Q L L+ A +P
Sbjct: 1748 LAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVP 1796



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 111/458 (24%), Positives = 162/458 (35%), Gaps = 59/458 (12%)

Query: 26   SGAAAPAGPGAGP--------APHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGK 77
            S   + + PGA P         P    GPA + M +P+   L      +P       P  
Sbjct: 1382 SPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPL-----ASPVSSTVSVP-L 1435

Query: 78   MTSLPLD--TQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLG--- 132
             +SLP+   T      SA  T+P     P TV+   G   L S  PP   +V +  G   
Sbjct: 1436 SSSLPISVPTTLPAPASAPLTIPIS--APLTVSAS-GPALLTSVTPPLAPVVPAAPGPPS 1492

Query: 133  -SFQGAASSASHLHTS-ASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSN 190
             +  GA+ SAS L    A+ P  S       P + + +SS    G  ST        +  
Sbjct: 1493 LAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVP-GLNSTVAPACSPVLVP 1551

Query: 191  AAYPSVSYPSLP--AGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPL----- 243
            A+  +  +PS P  A      +  + +A           +   TAI  PSP PPL     
Sbjct: 1552 ASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPV 1611

Query: 244  ----PSQQHHQQQSLSGYSTLTWSS-PGLPSTQDNLIRNHTGSLAVANNNPTITVADSLS 298
                P        S +    +  SS PG      + +   T  LA ++    +       
Sbjct: 1612 LAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSP 1671

Query: 299  CPVMQNVQPPKSSPVVSTVLSGSSGSSS----TRTP----PTANHPVEPVTS-VTQPSEL 349
             P   + Q    +P ++  L GSS S +    T  P    PT    + P +S V  P++ 
Sbjct: 1672 LPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQT 1731

Query: 350  LQ-QKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDA 408
            L    G   G       + AP PL+  S               + + T + +P  +S   
Sbjct: 1732 LSLAPGPPLGPTQTLSLAPAP-PLAPASPVGP-----------APAHTLTLAPASSSASL 1779

Query: 409  LEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPA 446
            L   S   +  S A  P   PA     A APA   +PA
Sbjct: 1780 LAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPA 1817



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 42/163 (25%)

Query: 422  ASSPAPDPAPEPDPASAPAPASAPAPVV----------PQPSKM---AKPFGYGYPTLQP 468
            AS+PA  PA  P P SAP P SAP P+           P PS++   + P     P   P
Sbjct: 2448 ASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTP 2507

Query: 469  GYQNATAPLISG-VQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQ--------- 518
               +   P  +  V PS+P+  G    P        +S+S+  L L   P+         
Sbjct: 2508 PPAHTPPPAQTCLVTPSSPLLLGPPSVP--------ISASVTNLPLGLRPEAELCAQALA 2559

Query: 519  -PESLR----------PVNLTQERNILPMTPVWAPVPNLNADL 550
             PESL            ++L   +++LP+     PV   N  L
Sbjct: 2560 SPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSL 2602



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 48/181 (26%), Positives = 68/181 (37%), Gaps = 19/181 (10%)

Query: 403  PNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYG 462
            PN    L     P     S   P   PA  P PA  P PA  P P        + P   G
Sbjct: 2471 PNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLG 2530

Query: 463  YPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESL 522
             P++         PL  G++P   + +     P+     +  SS    LSL     P+ L
Sbjct: 2531 PPSVPISASVTNLPL--GLRPEAELCAQALASPESLELASVASSETSSLSL---VPPKDL 2585

Query: 523  RPVNL----TQERNILPMTPVWAPVPNLNADLKKL-----NCSPDSFR-CTLTNIPQTQA 572
             PV +      E+N L +TP     P+L  +   +       +PDS    TLT +P+ + 
Sbjct: 2586 LPVAVEILPVSEKN-LSLTP---SAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEE 2641

Query: 573  L 573
            L
Sbjct: 2642 L 2642



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 3/73 (4%)

Query: 389  GVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPA--PASAPA 446
            G  + +  ++ +P+ +++      + P    +    P P P P P PASAPA  PA  P 
Sbjct: 2401 GARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPV 2460

Query: 447  PV-VPQPSKMAKP 458
            PV  P P     P
Sbjct: 2461 PVSAPVPISAPNP 2473



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 61/257 (23%), Positives = 101/257 (39%), Gaps = 41/257 (15%)

Query: 303  QNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVE----PVT----SVTQPSELLQQKG 354
            Q +  P+S  + S  ++ S  SS +  PP    PV     PV+    S+T  +  L    
Sbjct: 2556 QALASPESLELAS--VASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLT--- 2610

Query: 355  VQYGEYVNNQASSAPTPLSSTSDDEEEEEED------EEAGVDSSSTTSSASPMPNSYDA 408
            ++ G   N Q   AP     T+     E E+      E  G++   + +S  P+    +A
Sbjct: 2611 LEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEA 2670

Query: 409  LEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPA-SAPAPVVPQPSKMAKP--------- 458
                +  ++  +   + +P+   E   A   AP+ S+ A   P+    A+P         
Sbjct: 2671 --DRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADV 2728

Query: 459  ----FGYGYPTLQPG---YQNATAPLISGVQPSNPVYSGFQQYPQQ---YPGVNQLSSSI 508
                 G G P   PG    +     L++ V+    V    QQ        PGV++ S+S 
Sbjct: 2729 EIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASP 2788

Query: 509  GGLSLQSSPQPESLRPV 525
            G  S++S   PES  P+
Sbjct: 2789 GSPSVRSMSGPESSPPI 2805



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 108/488 (22%), Positives = 165/488 (33%), Gaps = 87/488 (17%)

Query: 1    MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAG-PGAGPAPHQQNGPAQNQMQVPSGYGL 59
            +S P  SS P +     P       + A+AP   P + P     +GPA      P     
Sbjct: 1431 VSVPLSSSLPISVPTTLP-------APASAPLTIPISAPLTVSASGPALLTSVTPP---- 1479

Query: 60   HHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSR 119
                 +AP    + GP  +               L T P+ + +     Q PG   L + 
Sbjct: 1480 -----LAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSS-----QTPGHPLLLA- 1528

Query: 120  GPPAPHIVGSTLGSFQGAASSASHLHTSA-SQPYSSFVNHYNSPAMYSASSSVASQGFPS 178
             P + H+ G  L S    A S   +  SA + P+ S  N   + A   A +S ASQ   +
Sbjct: 1529 -PTSSHVPG--LNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALAT 1585

Query: 179  TCGHYAMSTVS----NAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAI 234
                 A    +    + A P    P L        +  S   P V  +  +S  G + A 
Sbjct: 1586 PLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTP-VPVMAPSSTPGTSLAS 1644

Query: 235  SHPSPLP-------------------PLPSQQHHQQQSLSGY--STLTWSSP-------- 265
            + P P P                   PLPS    Q  +L+     TL  SSP        
Sbjct: 1645 ASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGT 1704

Query: 266  GLPS----TQ-------DNLIRNHTGSLAVANNNP-----TITVADSLSCPVMQNVQPPK 309
            G P     TQ        +L+     +L++A   P     T+++A +   P +    P  
Sbjct: 1705 GNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPA---PPLAPASPVG 1761

Query: 310  SSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAP 369
             +P  +  L+ +S S+S   P +    V+ +T    P   L   G    + +    +S  
Sbjct: 1762 PAPAHTLTLAPASSSASLLAPAS----VQTLTLSPAPVPTL---GPAAAQTLALAPASTQ 1814

Query: 370  TPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDP 429
            +P S  S             V   S    +   P++     G   P   ++S   P P  
Sbjct: 1815 SPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRR 1874

Query: 430  APEPDPAS 437
             P P P S
Sbjct: 1875 QPPPPPRS 1882


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 134/576 (23%), Positives = 188/576 (32%), Gaps = 70/576 (12%)

Query: 2   SAP-AGSSHPAA-SARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGL 59
           SAP AG +  A  S+R P     A+  G  AP      P P    G A    + P   G 
Sbjct: 73  SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR-PGPLG- 130

Query: 60  HHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVN-------QQPG 112
             Q  +  S   +   GK T  P  +      SA     T   TP T +       +  G
Sbjct: 131 --QKGLRISAEETVARGKATEAPKRSAL----SAGARRDTSGPTPGTPSPAMARRSRAAG 184

Query: 113 AQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTS---ASQPYSSFVNHYNSPAMYSASS 169
            +    R  P+      T G  +  +S++ H  T    A++   S       PA  S SS
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244

Query: 170 SVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQN--APTVRPVKDNSF 227
           S      P+  G  A  T    A+PS   P         Q+   +   AP + P+  +  
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304

Query: 228 SGQNTAISHPSPLPP-LPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVAN 286
           +  + + +  S  PP LP+  H    +    + L  + P  PS   +L      +L    
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS-PSAPPSL-----QTLPSPP 358

Query: 287 NNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQP 346
             P      SL  P +Q       SP +S + +    +      P    P  P  S   P
Sbjct: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS--PP 416

Query: 347 SELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSY 406
              L     Q    +      AP     +   +          V  S+T  S +P     
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP----- 471

Query: 407 DALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTL 466
                   P + +     P   PA  P   SA  P  AP P+   P ++AKP     P L
Sbjct: 472 --------PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523

Query: 467 QPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSP---QPESLR 523
                 AT PL +   P           P  +PG    S S    SL  SP    P    
Sbjct: 524 ------ATPPLQALPSP-----------PASFPGQAPFSPS---ASLPMSPLATPPPQAP 563

Query: 524 PVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPDS 559
           PV       + P  P     P L A  +     PD+
Sbjct: 564 PVLAAPLLQVPPSPPA---SPTLQAPRRPPTPGPDT 596


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 99/444 (22%), Positives = 163/444 (36%), Gaps = 67/444 (15%)

Query: 120  GPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPST 179
            G P+ H   ++ GS   + S + H H+S+S   +S      S     +SSS  S    S+
Sbjct: 1075 GKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS 1134

Query: 180  CGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSP 239
             G    S   N++       S P   T   + +  ++  ++P       G+ +++ +PS 
Sbjct: 1135 QGSSGSSQSKNSSQSGGKPGSSPI--TKHGLSSGSSSTKMKP------QGKPSSLMNPSL 1186

Query: 240  LPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSC 299
              P  S  H +     G   L      +P T  +       S     ++ + T       
Sbjct: 1187 SKPNISPSHSRPP--GGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGT------- 1237

Query: 300  PVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGE 359
                      SS + S+   GSSGS S +TPP++N      +S +     +     Q+G 
Sbjct: 1238 --------SSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGS 1289

Query: 360  YVNNQASSAPTPLSS-----------TSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDA 408
                  S    P  +           TS    E+  D + GV   ST SS+ PM + ++ 
Sbjct: 1290 SKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGV---STNSSSHPMSSKHN- 1345

Query: 409  LEGGSY--------PDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQ-----PSKM 455
            + GG +         D    S S  + D + +   +           ++ +     PS  
Sbjct: 1346 MSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIK 1405

Query: 456  AK--------PFGYGYPTLQPGYQNATAPLISGVQP----SNPVYSGFQQY-PQQYPGVN 502
            AK          G G        +N  +PLISG  P     +P +S    Y PQ     +
Sbjct: 1406 AKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSES 1465

Query: 503  QLSSSIGGLSLQSSP-QPESLRPV 525
            +  SSI   S Q+SP   + +RP+
Sbjct: 1466 ESGSSIAEKSYQNSPSSDDGIRPL 1489


>gi|188497758 ubiquitin associated protein 2-like isoform a [Homo
           sapiens]
          Length = 1087

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 72/320 (22%), Positives = 124/320 (38%), Gaps = 29/320 (9%)

Query: 156 VNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQN 215
           ++ Y S    SASSS A     ++    + ST+S+       Y S P   T    +TSQN
Sbjct: 529 LSDYESTPTTSASSSQAPSSLYTSTASESSSTISSNQSQESGYQSGPIQST---TYTSQN 585

Query: 216 APTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLI 275
                  +  S   +     +PS +   P  Q    Q+ +G+S++   +  L +TQ   +
Sbjct: 586 NAQGPLYEQRSTQTRR----YPSSISSSP--QKDLTQAKNGFSSV--QATQLQTTQS--V 635

Query: 276 RNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANH 335
              TGS   +++  T ++             PP +  V +  L  ++   S+     ++ 
Sbjct: 636 EGATGSAVKSDSPSTSSI-------------PPLNETVSAASLLTTTNQHSSSLGGLSHS 682

Query: 336 PVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSST 395
              P T+ TQ S  L  +        ++  +S  T L ++ + E            +SST
Sbjct: 683 EEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSST 742

Query: 396 TSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPA---PVVPQP 452
            S+  P+ +   +L  GS   +   S S+            S  AP + P    P++P P
Sbjct: 743 VSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNP 802

Query: 453 SKMAKPFGYGYPTLQPGYQN 472
             MA    + YP    GY +
Sbjct: 803 YIMAPGLLHAYPPQVYGYDD 822



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 103/441 (23%), Positives = 158/441 (35%), Gaps = 47/441 (10%)

Query: 92  SALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQP 151
           S+LYT  T + + +T++     +  Y  GP    I  +T  S   A        ++ ++ 
Sbjct: 547 SSLYT-STASESSSTISSNQSQESGYQSGP----IQSTTYTSQNNAQGPLYEQRSTQTRR 601

Query: 152 YSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVS-NAAYPSVSYPSLPAGDTYGQM 210
           Y S ++  +SP       + A  GF S       +T S   A  S      P+  +   +
Sbjct: 602 YPSSIS--SSP---QKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIPPL 656

Query: 211 FTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPST 270
             + +A ++     N  S     +SH   +P   + QH    S    +  + +S G  ST
Sbjct: 657 NETVSAASLLTTT-NQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTST 715

Query: 271 QDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSS-----GSS 325
              L   HT   + AN + + +   + S  V     PP    V S++ SGSS     GS+
Sbjct: 716 STLL---HTSVESEANLHSSSSTFSTTSSTVS---APPPVVSVSSSLNSGSSLGLSLGSN 769

Query: 326 STRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAP------TPLSSTSDDE 379
           ST T  T +      TS   P  L    GV     + N    AP       P     DD 
Sbjct: 770 STVTASTRSSVA--TTSGKAPPNL--PPGVP--PLLPNPYIMAPGLLHAYPPQVYGYDDL 823

Query: 380 EEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAP 439
           +  +        S    +  +P+     +L    Y   L+      A  PAP    A   
Sbjct: 824 QMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQ 883

Query: 440 APASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYP 499
              +       Q         +  P L PGY   + P  +GV P  P  S FQ  P  +P
Sbjct: 884 QNQTQTHHTTQQT--------FLNPALPPGYSYTSLPYYTGV-PGLP--STFQYGPAVFP 932

Query: 500 GVNQLSSSIG-GLSLQSSPQP 519
                S   G  +S+ +S  P
Sbjct: 933 VAPTSSKQHGVNVSVNASATP 953



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 69/348 (19%), Positives = 127/348 (36%), Gaps = 29/348 (8%)

Query: 106 TVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMY 165
           T   QP +   +S      H + S LG   G    A    T+ SQ    F+  + +    
Sbjct: 322 TAISQPASGNTFSH-----HSMVSMLGKGFGDVGEAKGGSTTGSQ----FLEQFKTAQAL 372

Query: 166 SASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSL--PAGDTYGQMFTSQNAPTVRP-- 221
           +  ++  SQ   +T   + M + + +  PS+    L  P+       FT + A T     
Sbjct: 373 AQLAAQHSQSGSTTTSSWDMGSTTQS--PSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTM 430

Query: 222 ----VKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRN 277
               +++ S +   +  + P P  PLPS+     Q   G S    SSP  P+ Q   ++ 
Sbjct: 431 MEVFLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSP-QPAQQK--LKQ 487

Query: 278 HTGSLAVANNNPTITV-----ADSLSCPVMQNVQPPKSSPVVSTVLS-GSSGSSSTRTPP 331
                ++ +  P + V     AD     +        S PV+S   S  ++ +SS++ P 
Sbjct: 488 QKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPS 547

Query: 332 TANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVD 391
           +        +S T  S   Q+ G Q G   +   +S         +    +     + + 
Sbjct: 548 SLYTSTASESSSTISSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSI- 606

Query: 392 SSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAP 439
           SSS     +   N + +++        S   ++ +   +  P  +S P
Sbjct: 607 SSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIP 654


>gi|188497756 ubiquitin associated protein 2-like isoform b [Homo
           sapiens]
          Length = 983

 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 72/320 (22%), Positives = 124/320 (38%), Gaps = 29/320 (9%)

Query: 156 VNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQN 215
           ++ Y S    SASSS A     ++    + ST+S+       Y S P   T    +TSQN
Sbjct: 529 LSDYESTPTTSASSSQAPSSLYTSTASESSSTISSNQSQESGYQSGPIQST---TYTSQN 585

Query: 216 APTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLI 275
                  +  S   +     +PS +   P  Q    Q+ +G+S++   +  L +TQ   +
Sbjct: 586 NAQGPLYEQRSTQTRR----YPSSISSSP--QKDLTQAKNGFSSV--QATQLQTTQS--V 635

Query: 276 RNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANH 335
              TGS   +++  T ++             PP +  V +  L  ++   S+     ++ 
Sbjct: 636 EGATGSAVKSDSPSTSSI-------------PPLNETVSAASLLTTTNQHSSSLGGLSHS 682

Query: 336 PVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSST 395
              P T+ TQ S  L  +        ++  +S  T L ++ + E            +SST
Sbjct: 683 EEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSST 742

Query: 396 TSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPA---PVVPQP 452
            S+  P+ +   +L  GS   +   S S+            S  AP + P    P++P P
Sbjct: 743 VSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNP 802

Query: 453 SKMAKPFGYGYPTLQPGYQN 472
             MA    + YP    GY +
Sbjct: 803 YIMAPGLLHAYPPQVYGYDD 822



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 103/441 (23%), Positives = 158/441 (35%), Gaps = 47/441 (10%)

Query: 92  SALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQP 151
           S+LYT  T + + +T++     +  Y  GP    I  +T  S   A        ++ ++ 
Sbjct: 547 SSLYT-STASESSSTISSNQSQESGYQSGP----IQSTTYTSQNNAQGPLYEQRSTQTRR 601

Query: 152 YSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVS-NAAYPSVSYPSLPAGDTYGQM 210
           Y S ++  +SP       + A  GF S       +T S   A  S      P+  +   +
Sbjct: 602 YPSSIS--SSP---QKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIPPL 656

Query: 211 FTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPST 270
             + +A ++     N  S     +SH   +P   + QH    S    +  + +S G  ST
Sbjct: 657 NETVSAASLLTTT-NQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTST 715

Query: 271 QDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSS-----GSS 325
              L   HT   + AN + + +   + S  V     PP    V S++ SGSS     GS+
Sbjct: 716 STLL---HTSVESEANLHSSSSTFSTTSSTVS---APPPVVSVSSSLNSGSSLGLSLGSN 769

Query: 326 STRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAP------TPLSSTSDDE 379
           ST T  T +      TS   P  L    GV     + N    AP       P     DD 
Sbjct: 770 STVTASTRSSVA--TTSGKAPPNL--PPGVP--PLLPNPYIMAPGLLHAYPPQVYGYDDL 823

Query: 380 EEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAP 439
           +  +        S    +  +P+     +L    Y   L+      A  PAP    A   
Sbjct: 824 QMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQ 883

Query: 440 APASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYP 499
              +       Q         +  P L PGY   + P  +GV P  P  S FQ  P  +P
Sbjct: 884 QNQTQTHHTTQQT--------FLNPALPPGYSYTSLPYYTGV-PGLP--STFQYGPAVFP 932

Query: 500 GVNQLSSSIG-GLSLQSSPQP 519
                S   G  +S+ +S  P
Sbjct: 933 VAPTSSKQHGVNVSVNASATP 953



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 69/348 (19%), Positives = 127/348 (36%), Gaps = 29/348 (8%)

Query: 106 TVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMY 165
           T   QP +   +S      H + S LG   G    A    T+ SQ    F+  + +    
Sbjct: 322 TAISQPASGNTFSH-----HSMVSMLGKGFGDVGEAKGGSTTGSQ----FLEQFKTAQAL 372

Query: 166 SASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSL--PAGDTYGQMFTSQNAPTVRP-- 221
           +  ++  SQ   +T   + M + + +  PS+    L  P+       FT + A T     
Sbjct: 373 AQLAAQHSQSGSTTTSSWDMGSTTQS--PSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTM 430

Query: 222 ----VKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRN 277
               +++ S +   +  + P P  PLPS+     Q   G S    SSP  P+ Q   ++ 
Sbjct: 431 MEVFLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSP-QPAQQK--LKQ 487

Query: 278 HTGSLAVANNNPTITV-----ADSLSCPVMQNVQPPKSSPVVSTVLS-GSSGSSSTRTPP 331
                ++ +  P + V     AD     +        S PV+S   S  ++ +SS++ P 
Sbjct: 488 QKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPS 547

Query: 332 TANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVD 391
           +        +S T  S   Q+ G Q G   +   +S         +    +     + + 
Sbjct: 548 SLYTSTASESSSTISSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSI- 606

Query: 392 SSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAP 439
           SSS     +   N + +++        S   ++ +   +  P  +S P
Sbjct: 607 SSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIP 654


>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 136/568 (23%), Positives = 194/568 (34%), Gaps = 100/568 (17%)

Query: 1   MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQ-MQVPSGYGL 59
           M+ P+        +R  P    A+   +AAPA PG  PA H    PA +Q M +PS    
Sbjct: 41  MNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPG--PAAHVY--PAGSQVMMIPSQI-- 94

Query: 60  HHQNYIAPSG-HYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYS 118
              +Y A  G +Y  G G+ T               Y VPTQ         QPGA   Y 
Sbjct: 95  ---SYPASQGAYYIPGQGRST---------------YVVPTQQYPV-----QPGAPGFYP 131

Query: 119 RGPPAPHIVGSTLGSFQGAASSASHLHT--SASQPYSSFVNHYNSPAMYSASSSVASQGF 176
              P      +  G++ GA   A  +    +   P    +N     A      ++  +  
Sbjct: 132 GASP------TEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDP 185

Query: 177 PSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMF--TSQNAPTVRPVKDNSFSGQNTAI 234
                      +S A   S   P    G    Q    T Q A  VRP  D+   G   A 
Sbjct: 186 NQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRP--DDRSQGAIIA- 242

Query: 235 SHPSPLPPLPSQQHHQQQSLSGYSTLTWS-SPGL-PSTQDNLIRNHTGSLAVANNNPTIT 292
                 P LP  +H   +S     + T S SP L P ++ NL                ++
Sbjct: 243 ----DRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLA--------------VLS 284

Query: 293 VADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQ 352
           +       +  +V+        ST +S  +G    R  P      EP+  V    E+   
Sbjct: 285 IPGDTMTTIQMSVEE-------STPISRETGEPY-RLSPEPTPLAEPILEV----EVTLS 332

Query: 353 KGVQYGEYVNNQASSAPTPLSSTSDDEEEEE-----EDEEAGVDSSSTTSSASPMPNSYD 407
           K V   E+ ++    APTPL+S + +  E       ED E  V+SS   +     P    
Sbjct: 333 KPVPESEF-SSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP---- 387

Query: 408 ALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGY-PTL 466
                      S S    AP   PE     AP+P +     V +P + AK       P  
Sbjct: 388 -----------SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 436

Query: 467 QPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVN 526
            P    ATAP  +       +    ++   +     +  S  GG  L   P   +  P N
Sbjct: 437 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEEL--LPPESTPIPAN 494

Query: 527 LTQERNILPMTPVWAPVPNLNADLKKLN 554
           L+Q       T V   VP     +K+LN
Sbjct: 495 LSQNLEAAAATQVAVSVPKRRRKIKELN 522


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 136/568 (23%), Positives = 194/568 (34%), Gaps = 100/568 (17%)

Query: 1   MSAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQ-MQVPSGYGL 59
           M+ P+        +R  P    A+   +AAPA PG  PA H    PA +Q M +PS    
Sbjct: 41  MNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPG--PAAHVY--PAGSQVMMIPSQI-- 94

Query: 60  HHQNYIAPSG-HYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYS 118
              +Y A  G +Y  G G+ T               Y VPTQ         QPGA   Y 
Sbjct: 95  ---SYPASQGAYYIPGQGRST---------------YVVPTQQYPV-----QPGAPGFYP 131

Query: 119 RGPPAPHIVGSTLGSFQGAASSASHLHT--SASQPYSSFVNHYNSPAMYSASSSVASQGF 176
              P      +  G++ GA   A  +    +   P    +N     A      ++  +  
Sbjct: 132 GASP------TEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRERKTIRIRDP 185

Query: 177 PSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMF--TSQNAPTVRPVKDNSFSGQNTAI 234
                      +S A   S   P    G    Q    T Q A  VRP  D+   G   A 
Sbjct: 186 NQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRP--DDRSQGAIIA- 242

Query: 235 SHPSPLPPLPSQQHHQQQSLSGYSTLTWS-SPGL-PSTQDNLIRNHTGSLAVANNNPTIT 292
                 P LP  +H   +S     + T S SP L P ++ NL                ++
Sbjct: 243 ----DRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLA--------------VLS 284

Query: 293 VADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQ 352
           +       +  +V+        ST +S  +G    R  P      EP+  V    E+   
Sbjct: 285 IPGDTMTTIQMSVEE-------STPISRETGEPY-RLSPEPTPLAEPILEV----EVTLS 332

Query: 353 KGVQYGEYVNNQASSAPTPLSSTSDDEEEEE-----EDEEAGVDSSSTTSSASPMPNSYD 407
           K V   E+ ++    APTPL+S + +  E       ED E  V+SS   +     P    
Sbjct: 333 KPVPESEF-SSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP---- 387

Query: 408 ALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGY-PTL 466
                      S S    AP   PE     AP+P +     V +P + AK       P  
Sbjct: 388 -----------SESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 436

Query: 467 QPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPVN 526
            P    ATAP  +       +    ++   +     +  S  GG  L   P   +  P N
Sbjct: 437 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEEL--LPPESTPIPAN 494

Query: 527 LTQERNILPMTPVWAPVPNLNADLKKLN 554
           L+Q       T V   VP     +K+LN
Sbjct: 495 LSQNLEAAAATQVAVSVPKRRRKIKELN 522


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 41/144 (28%), Positives = 66/144 (45%), Gaps = 6/144 (4%)

Query: 365  ASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASS 424
            ASS+ +  SS+S           +   SSS++SS+S   +S  +    S     SSS+S+
Sbjct: 2613 ASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSST 2672

Query: 425  PAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTL-QPGYQN-ATAPLISGVQ 482
               D +   D  +APAP + P+     P+K  K  G   P+   PG +  A  P     Q
Sbjct: 2673 TDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQ 2732

Query: 483  PSNPV----YSGFQQYPQQYPGVN 502
            P+ P+     +G +  P++  GV+
Sbjct: 2733 PTQPLQPKAQAGAKSRPKKREGVH 2756



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 45/196 (22%), Positives = 80/196 (40%), Gaps = 16/196 (8%)

Query: 310  SSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAP 369
            +SP  S+  S SS SSS+ +  +++      +S +  S              ++ +SS+ 
Sbjct: 2610 ASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS---SSSSSSSS 2666

Query: 370  TPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDP 429
            +  SST+D++     D+EA    ++  S+ + +P       G + P   S    +PAP P
Sbjct: 2667 SSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQP 2726

Query: 430  APEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQ--------PGYQNATAPLISGV 481
               P   + P    A A    +P K     G   PT +        P  +N   P I+  
Sbjct: 2727 QAPPPQPTQPLQPKAQAGAKSRPKKRE---GVHLPTTKELAKRQRLPSVEN--RPKIAAF 2781

Query: 482  QPSNPVYSGFQQYPQQ 497
             P+  ++  F +  Q+
Sbjct: 2782 LPARQLWKWFGKPTQR 2797



 Score = 37.7 bits (86), Expect = 0.070
 Identities = 53/254 (20%), Positives = 90/254 (35%), Gaps = 40/254 (15%)

Query: 350  LQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDAL 409
            LQQ+  Q  E +   A      L +     E EE+  + G++++     A+  P     L
Sbjct: 916  LQQQAAQALE-LQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPG----L 970

Query: 410  EGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPG 469
                 P + +  A +     +P P P ++P  A+  A V+ +   ++KP  Y YP     
Sbjct: 971  LPRKPPGLAAGPAGTYGKAVSPPPSPRASPV-AALKAKVIQKLEDVSKPPAYAYPATPSS 1029

Query: 470  YQN----ATAPLISGV--------------------QPSNPVYSGFQQYPQQYPGVNQLS 505
            +      A+ P   G+                    +  +P  + F   P +YP    L 
Sbjct: 1030 HPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYP-FQALP 1088

Query: 506  SSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPN---LNADLKKLNCSPDSFRC 562
               G       P P  L+P        + P  P+ A  P    L+ + K +  SP     
Sbjct: 1089 PHYG------RPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITE 1142

Query: 563  TLTNIPQTQALLNK 576
             L   P+ + L  +
Sbjct: 1143 PLREGPEEEPLAER 1156



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 44/168 (26%), Positives = 67/168 (39%), Gaps = 29/168 (17%)

Query: 308  PKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASS 367
            P++SPV +              PP   +P  P +  T P                  AS 
Sbjct: 996  PRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPP----------------PASP 1039

Query: 368  APTPLSSTSDDEEE---EEEDEEAGVDSSSTTSSA-SPMPNSY--DALE---GGSYPDML 418
             PTP  +  ++  E   E++D E   ++ S   +  S +P  Y   AL    G  YP +L
Sbjct: 1040 PPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLL 1099

Query: 419  SSSASSPAPDPAPE-PDPASAP---APASAPAPVVPQPSKMAKPFGYG 462
              +A++ A   AP+ P PA  P   A +    P+   PSK+ +P   G
Sbjct: 1100 QPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREG 1147



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 5/83 (6%)

Query: 381  EEEEDEEAGVDSSSTTSSASPMPNSYD--ALEGGSYPDMLSSSASSPAPDPAPEPDP-AS 437
            +E       ++ SST  S    P   D  A    + P     S + PA    P P+P A 
Sbjct: 2355 DEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAE 2414

Query: 438  APAPAS--APAPVVPQPSKMAKP 458
             PAPA+  APAP++  P+   KP
Sbjct: 2415 LPAPATSLAPAPLITMPATRPKP 2437



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 43/165 (26%), Positives = 72/165 (43%), Gaps = 16/165 (9%)

Query: 129  STLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTV 188
            S+  S   ++SS+S   +S+S   SS  +  +S +  S+SSS ++    S+C     +  
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAP 2687

Query: 189  SNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQH 248
            +  A PS +  +LP   T       + A   RP   +   G+ T    P   PP P+Q  
Sbjct: 2688 APTAGPS-AQAALPTKAT-------KQAGKARPSAHS--PGKKTPAPQPQAPPPQPTQP- 2736

Query: 249  HQQQSLSGYSTLTWSSPG--LPSTQDNLIRNHTGSLAVANNNPTI 291
             Q ++ +G  +      G  LP+T++   R    S+    N P I
Sbjct: 2737 LQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSV---ENRPKI 2778



 Score = 31.6 bits (70), Expect = 5.0
 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 7/98 (7%)

Query: 338  EPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEE--EEDEEAGVDSSST 395
            +P TS  QP  LL ++      + ++   S     SS  +DEEEE  EEDE +G      
Sbjct: 1791 KPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLG 1850

Query: 396  TSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEP 433
                +  P   ++  G     +L+  A+S  P P   P
Sbjct: 1851 ARERALSPGLEESGLG-----LLARFAASALPSPTVGP 1883



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 32/99 (32%), Positives = 42/99 (42%), Gaps = 22/99 (22%)

Query: 391  DSSSTTSSASP---MPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAP 447
            D ++T    +P   +P++  ALE  S P     S  SP     PEP    A AP + PAP
Sbjct: 2343 DRAATLEEGNPTDEVPSTPLALEPSSTP----GSKKSP-----PEPVDKRAKAPKARPAP 2393

Query: 448  VVPQPSKMA-------KPFGYGYPTLQPGYQNATAPLIS 479
              P P+  A       +PF        P    A APLI+
Sbjct: 2394 PQPSPAPPAFTSCPAPEPFA---ELPAPATSLAPAPLIT 2429


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 102/480 (21%), Positives = 162/480 (33%), Gaps = 93/480 (19%)

Query: 5    AGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNY 64
            + S  P ASA +PP    +  +  +AP      P P   + P                  
Sbjct: 1743 SASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAP------------------ 1784

Query: 65   IAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAP 124
                            +P  T      S    VP   + P + +    A       P + 
Sbjct: 1785 ----------------VPASTLAPVLASTSAPVPASPLAPVSASASVSASV-----PAST 1823

Query: 125  HIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYA 184
                 T  S   +A + + +  S S P S  +       + SAS  + +    ST     
Sbjct: 1824 SAAAITSSSAPASAPAPTPILASVSTPASVTI-------LASASIPILASALASTSAPTP 1876

Query: 185  MSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPT----VRPVKDNSFSGQNTAISHPSPL 240
                S+ A P ++ P++PA           +APT    + P   ++ +   T +S P+P 
Sbjct: 1877 APAASSPAAPVITAPTIPA-----------SAPTASVPLAPASASAPAPAPTPVSAPNPA 1925

Query: 241  PPLPSQQHHQQ--------QSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTIT 292
            PP P+Q   Q         Q+ S  S     S  LPS Q     N T  +A   +  T  
Sbjct: 1926 PPAPAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRLPSAQ---TPNGTDYVASGKSIQTPQ 1982

Query: 293  VADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSV-TQPSELLQ 351
               +L+  +  N   P   P V   +S   G  S   PP+ +   +P+TS  + PS    
Sbjct: 1983 SHGTLTAELWDNKVAP---PAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGA 2039

Query: 352  QKG-----------VQYGEYVNNQASSAPTP-LSSTSDD-----EEEEEEDEEAGVDSSS 394
            + G           +Q+G   +N   +   P LS  S D     +E+ ++   AG   + 
Sbjct: 2040 KNGQESGLEIGTDTIQFGAPASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQ 2099

Query: 395  TTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSK 454
                 SP+ N             L +     A    PE     +PA   +  PV  + +K
Sbjct: 2100 KLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPSPATVRSTDPVTTKETK 2159



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 56/232 (24%), Positives = 89/232 (38%), Gaps = 32/232 (13%)

Query: 235  SHPSPLPP--LPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTIT 292
            S  S LPP     Q    QQ+ S  S    +S  LP +    +   T +   A   P   
Sbjct: 1720 SQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTP--- 1776

Query: 293  VADSLSCPVMQNVQPP----KSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSE 348
            V  S S PV  +   P     S+PV ++ L+  S S+S      A+     +TS + P+ 
Sbjct: 1777 VPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPA- 1835

Query: 349  LLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDA 408
                            ++ APTP+ ++            A +   ++  +++  P    A
Sbjct: 1836 ----------------SAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPA 1879

Query: 409  LEGGSYPDMLSSSASSPAPD------PAPEPDPASAPAPASAPAPVVPQPSK 454
                + P + + +  + AP       PA    PA AP P SAP P  P P++
Sbjct: 1880 ASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPPAPAQ 1931



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 46/173 (26%), Positives = 70/173 (40%), Gaps = 27/173 (15%)

Query: 307  PPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQAS 366
            PP+ +   +T +  +  S+S   PP A+ P+ P TS + P+                 ++
Sbjct: 1726 PPRFAKKQATGIQQAQSSASV--PPLASAPLPPSTSASVPA-----------------ST 1766

Query: 367  SAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPA 426
            SAP P + T            A   +    S+++P+P S  A    S     S SAS PA
Sbjct: 1767 SAPLPATLTPVPASTSAP-VPASTLAPVLASTSAPVPASPLAPVSAS----ASVSASVPA 1821

Query: 427  PDPAPEPDPASAPAPASAPAPV---VPQPSKMAKPFGYGYPTLQPGYQNATAP 476
               A     +SAPA A AP P+   V  P+ +        P L     + +AP
Sbjct: 1822 STSAAAITSSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAP 1874



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 84/406 (20%), Positives = 126/406 (31%), Gaps = 62/406 (15%)

Query: 73   QGPGKMTSLPLDTQCGDYY---SALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGS 129
            Q P    S     Q   +Y   S L+      + P ++ QQ G Q   S+      I   
Sbjct: 2373 QNPQVYVSQSAAAQIPAFYMDTSHLFNTQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIP 2432

Query: 130  TLGSFQG------------AASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFP 177
                 QG            A S A  L +S+ QPY S       PA   +S S  S    
Sbjct: 2433 IYAPLQGQHQAQLSLGAGPAVSQAQELFSSSLQPYRS------QPAFMQSSLSQPSVVLS 2486

Query: 178  STCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHP 237
             T  H          +P+V +  L    +                          A    
Sbjct: 2487 GTAIHN---------FPTVQHQELAKAQS------------------------GLAFQQT 2513

Query: 238  SPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRN---HTGSLAVANNNPTITVA 294
            S   P+P    HQ    SG          L   + NL +    ++G +           A
Sbjct: 2514 SNTQPIPILYEHQLGQASGLGGSQLIDTHLLQARANLTQASNLYSGQVQQPGQTNFYNTA 2573

Query: 295  DSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKG 354
             S S   +Q V  P  +  +S    GS+G      P T   P++  T   Q   L +   
Sbjct: 2574 QSPSA--LQQVTVPLPASQLSLPNFGSTGQPLIALPQTLQPPLQHTTPQAQAQSLSRPAQ 2631

Query: 355  VQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTT---SSASPMPNSYDALEG 411
            V         A +  + +++T    E E +   +G+D    T   +  S  P S      
Sbjct: 2632 VSQPFRGLIPAGTQHSMIATTGKMSEMELKAFGSGIDIKPGTPPIAGRSTTPTSSPFRAT 2691

Query: 412  GSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAK 457
             + P+  SS  +S       +  PA+       P    PQ  + A+
Sbjct: 2692 STSPNSQSSKMNSIVYQKQFQSAPATVRMTQPFPTQFAPQAKQRAE 2737



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 87/427 (20%), Positives = 140/427 (32%), Gaps = 105/427 (24%)

Query: 100  QNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHY 159
            Q V P TV  QP +  +    PP PH        +Q       HL +    P    +  Y
Sbjct: 693  QGVLPQTVPSQPSSSTV----PPPPH-----RPLYQPMQPHPQHLASMGFDPRWLMMQSY 743

Query: 160  NSPAMYSASSSV-------------------ASQGFPSTCG---HYAMSTVSNAAYPSVS 197
              P M S   ++                     +G P++     H A S   +A   S+S
Sbjct: 744  MDPRMMSGRPAMDIPPIHPGMIPPKPLMRRDQMEGSPNSSESFEHIARSARDHAI--SLS 801

Query: 198  YPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGY 257
             P +  G         Q A T +  ++        A+     +    S +H+Q ++    
Sbjct: 802  EPRMLWGSDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQ-ITAAYSVEHNQLEAHPKA 860

Query: 258  STLTWSSPG-----LPSTQDNLIRNHTGSLAVANNNPTITVAD---SLSCPVMQNVQPPK 309
              +  SS       L  + +++  +HT     ANN      A    +LS P  + +   +
Sbjct: 861  DFIRESSEAQVQKFLSRSVEDVRPHHTD----ANNQSACFEAPDQKTLSAPQEERISAVE 916

Query: 310  SSPVVSTVLSGSSGSSSTRTP------PTANHP------VEPVTSVTQPSELLQQKGVQY 357
            S P  S   S S GS+ T+ P      P+A  P      ++    + +P E  +++G   
Sbjct: 917  SQP--SRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIR 974

Query: 358  G------EYVNNQASSA---PTPLSSTSDD---------------------EEEEEEDEE 387
                   E V    S     P P S+  ++                     EE E+  E+
Sbjct: 975  SSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEK 1034

Query: 388  AGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAP 447
             G  +   T      P   +  +                P P P P P +   P S P P
Sbjct: 1035 EGEKAEKVTEKVVVKPEKTEKKD---------------LPPPPPPPQPPAPIQPQSVPPP 1079

Query: 448  VVPQPSK 454
            + P+  K
Sbjct: 1080 IQPEAEK 1086



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 40/162 (24%), Positives = 65/162 (40%), Gaps = 25/162 (15%)

Query: 334  NHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSS 393
            +HP   VT +  P   L   G  + E V+ +            D+E  ++E++   V + 
Sbjct: 1662 DHP--EVTVIEDPQSNLNDDG--FTEVVSKKQQKR------LQDEERRKKEEQVIQVWNK 1711

Query: 394  STT-----SSASPMPNSYDALEGGSYPDMLSSSASSP-APDPAPEPDPASAPAPASAPAP 447
                    S  S +P  +   +        SS++  P A  P P    AS PA  SAP P
Sbjct: 1712 KNANEKGRSQTSKLPPRFAKKQATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLP 1771

Query: 448  --VVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPV 487
              + P P+  + P      TL P   + +AP+     P++P+
Sbjct: 1772 ATLTPVPASTSAPVPAS--TLAPVLASTSAPV-----PASPL 1806


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 114/479 (23%), Positives = 155/479 (32%), Gaps = 94/479 (19%)

Query: 4   PAGSSHPAASARIPPKFGGAAVSGAAAP--AGPGAGPAPHQQNGPAQN--QMQVPSGYGL 59
           PA SS P  + ++P    G   S  A P    P A  AP+Q   P        +     L
Sbjct: 195 PAPSSAPPGTPQLPTP--GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 252

Query: 60  HHQNYIAPSGHYSQGPGKMTSL-PLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYS 118
           H Q    PS H    P     L PL    G   +  +  P                 L+ 
Sbjct: 253 HPQR--PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP----------------LHG 294

Query: 119 RGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPS 178
           +GPP PH                       S      + H   P  +      ASQG   
Sbjct: 295 QGPPGPH-----------------------SLQAGPLLQHPGPPQPFGLPPQ-ASQG--- 327

Query: 179 TCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPS 238
                 + T   AAYP  S   LPA  +  Q   SQ  P  +P+     +  +      +
Sbjct: 328 ---QAPLGTSPAAAYPHTSL-QLPASQSALQ---SQQPPREQPLPPAPLAMPHIKPPPTT 380

Query: 239 PLPPLPSQQHHQQQS-LSGYSTLTWSS--PGLPSTQ--DNLIRNHTGSLAVANNNPTITV 293
           P+P LP+ Q H+    LSG S  + ++  P  P+ +   +L  +H  S            
Sbjct: 381 PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS------------ 428

Query: 294 ADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQK 353
           A      +M   QP  SSP     L+     S    PP A+HP   +  V       Q  
Sbjct: 429 AHPPPLQLMPQSQPLPSSPAQPPGLT----QSQNLPPPPASHPPTGLHQVAPQPPFAQHP 484

Query: 354 GVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGS 413
            V  G          P    STS           AG   +S     S    S  ++ GGS
Sbjct: 485 FVPGGP-----PPITPPTCPSTSTPP--------AG-PGTSAQPPCSGAAASGGSIAGGS 530

Query: 414 YPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQN 472
              + +      A D A EP+    P  + +P P V      A      Y  L  GY +
Sbjct: 531 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 589



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 61/294 (20%), Positives = 100/294 (34%), Gaps = 30/294 (10%)

Query: 303 QNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQY-GEYV 361
           + V+   SSP+ S        +S T      +        +++P+   + +G       V
Sbjct: 80  KKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSV 139

Query: 362 NNQASSAPTPLSS---TSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDML 418
           N++ SS P  +     ++       +D E+  DSS+        P +  A  G +     
Sbjct: 140 NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS 199

Query: 419 SSSASSPAPDPAPEPDPASAPAPASAPAPVVP-QPSKMAKPFGYGYPTLQPGYQNATAPL 477
           +   +   P P P P   + P   S  A   P QP     P  + +    P         
Sbjct: 200 APPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP--------- 250

Query: 478 ISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSL----------QSSPQPESLRPVNL 527
              + P  P       +P  +P +  L+ S G  S           Q  P P SL+   L
Sbjct: 251 --ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL 308

Query: 528 TQERNILPMTPVWAPVPNLNADLKKLNCSP-DSFRCTLTNIPQTQALLNKAKLP 580
            Q     P  P   P P  +     L  SP  ++  T   +P +Q+ L   + P
Sbjct: 309 LQHPG--PPQPFGLP-PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 359



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 72/323 (22%), Positives = 109/323 (33%), Gaps = 28/323 (8%)

Query: 263 SSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSS 322
           +SP +PS QD    N + S + A          +L  P      P  + P    + +   
Sbjct: 157 TSPSIPSPQD----NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 212

Query: 323 GSSSTRTPPTANHPVEPVTSVTQ-PSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEE 381
             S+T  PP  +       +  Q P+  +    +Q    ++ Q   +P P    S     
Sbjct: 213 TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 272

Query: 382 EEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAP 441
           +     AG    S  S A P       L G   P   S  A      P P P P   P  
Sbjct: 273 QPLTGSAG--QPSAPSHAQP------PLHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPPQ 323

Query: 442 AS-APAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPG 500
           AS   AP+   P+          P  Q   Q+   P    + P+ P+     + P   P 
Sbjct: 324 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA-PLAMPHIKPPPTTP- 381

Query: 501 VNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPDSF 560
           + QL +       Q+   P  L   +       LP  P   P+ +L+      +  P + 
Sbjct: 382 IPQLPAP------QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST-----HHPPSAH 430

Query: 561 RCTLTNIPQTQALLNKAKLPLGL 583
              L  +PQ+Q L +    P GL
Sbjct: 431 PPPLQLMPQSQPLPSSPAQPPGL 453


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 114/479 (23%), Positives = 155/479 (32%), Gaps = 94/479 (19%)

Query: 4    PAGSSHPAASARIPPKFGGAAVSGAAAP--AGPGAGPAPHQQNGPAQN--QMQVPSGYGL 59
            PA SS P  + ++P    G   S  A P    P A  AP+Q   P        +     L
Sbjct: 749  PAPSSAPPGTPQLPTP--GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 806

Query: 60   HHQNYIAPSGHYSQGPGKMTSL-PLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYS 118
            H Q    PS H    P     L PL    G   +  +  P                 L+ 
Sbjct: 807  HPQR--PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP----------------LHG 848

Query: 119  RGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPS 178
            +GPP PH                       S      + H   P  +      ASQG   
Sbjct: 849  QGPPGPH-----------------------SLQAGPLLQHPGPPQPFGLPPQ-ASQG--- 881

Query: 179  TCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPS 238
                  + T   AAYP  S   LPA  +  Q   SQ  P  +P+     +  +      +
Sbjct: 882  ---QAPLGTSPAAAYPHTSL-QLPASQSALQ---SQQPPREQPLPPAPLAMPHIKPPPTT 934

Query: 239  PLPPLPSQQHHQQQS-LSGYSTLTWSS--PGLPSTQ--DNLIRNHTGSLAVANNNPTITV 293
            P+P LP+ Q H+    LSG S  + ++  P  P+ +   +L  +H  S            
Sbjct: 935  PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS------------ 982

Query: 294  ADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQK 353
            A      +M   QP  SSP     L+     S    PP A+HP   +  V       Q  
Sbjct: 983  AHPPPLQLMPQSQPLPSSPAQPPGLT----QSQNLPPPPASHPPTGLHQVAPQPPFAQHP 1038

Query: 354  GVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGS 413
             V  G          P    STS           AG   +S     S    S  ++ GGS
Sbjct: 1039 FVPGGP-----PPITPPTCPSTSTPP--------AG-PGTSAQPPCSGAAASGGSIAGGS 1084

Query: 414  YPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQN 472
               + +      A D A EP+    P  + +P P V      A      Y  L  GY +
Sbjct: 1085 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 1143



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 61/294 (20%), Positives = 100/294 (34%), Gaps = 30/294 (10%)

Query: 303 QNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQY-GEYV 361
           + V+   SSP+ S        +S T      +        +++P+   + +G       V
Sbjct: 634 KKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSV 693

Query: 362 NNQASSAPTPLSS---TSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDML 418
           N++ SS P  +     ++       +D E+  DSS+        P +  A  G +     
Sbjct: 694 NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS 753

Query: 419 SSSASSPAPDPAPEPDPASAPAPASAPAPVVP-QPSKMAKPFGYGYPTLQPGYQNATAPL 477
           +   +   P P P P   + P   S  A   P QP     P  + +    P         
Sbjct: 754 APPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP--------- 804

Query: 478 ISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSL----------QSSPQPESLRPVNL 527
              + P  P       +P  +P +  L+ S G  S           Q  P P SL+   L
Sbjct: 805 --ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL 862

Query: 528 TQERNILPMTPVWAPVPNLNADLKKLNCSP-DSFRCTLTNIPQTQALLNKAKLP 580
            Q     P  P   P P  +     L  SP  ++  T   +P +Q+ L   + P
Sbjct: 863 LQHPG--PPQPFGLP-PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 72/323 (22%), Positives = 109/323 (33%), Gaps = 28/323 (8%)

Query: 263  SSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSS 322
            +SP +PS QD    N + S + A          +L  P      P  + P    + +   
Sbjct: 711  TSPSIPSPQD----NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 766

Query: 323  GSSSTRTPPTANHPVEPVTSVTQ-PSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEE 381
              S+T  PP  +       +  Q P+  +    +Q    ++ Q   +P P    S     
Sbjct: 767  TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 826

Query: 382  EEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAP 441
            +     AG    S  S A P       L G   P   S  A      P P P P   P  
Sbjct: 827  QPLTGSAG--QPSAPSHAQP------PLHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPPQ 877

Query: 442  AS-APAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPG 500
            AS   AP+   P+          P  Q   Q+   P    + P+ P+     + P   P 
Sbjct: 878  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA-PLAMPHIKPPPTTP- 935

Query: 501  VNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPDSF 560
            + QL +       Q+   P  L   +       LP  P   P+ +L+      +  P + 
Sbjct: 936  IPQLPAP------QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST-----HHPPSAH 984

Query: 561  RCTLTNIPQTQALLNKAKLPLGL 583
               L  +PQ+Q L +    P GL
Sbjct: 985  PPPLQLMPQSQPLPSSPAQPPGL 1007


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 114/479 (23%), Positives = 155/479 (32%), Gaps = 94/479 (19%)

Query: 4    PAGSSHPAASARIPPKFGGAAVSGAAAP--AGPGAGPAPHQQNGPAQN--QMQVPSGYGL 59
            PA SS P  + ++P    G   S  A P    P A  AP+Q   P        +     L
Sbjct: 749  PAPSSAPPGTPQLPTP--GPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 806

Query: 60   HHQNYIAPSGHYSQGPGKMTSL-PLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYS 118
            H Q    PS H    P     L PL    G   +  +  P                 L+ 
Sbjct: 807  HPQR--PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPP----------------LHG 848

Query: 119  RGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPS 178
            +GPP PH                       S      + H   P  +      ASQG   
Sbjct: 849  QGPPGPH-----------------------SLQAGPLLQHPGPPQPFGLPPQ-ASQG--- 881

Query: 179  TCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPS 238
                  + T   AAYP  S   LPA  +  Q   SQ  P  +P+     +  +      +
Sbjct: 882  ---QAPLGTSPAAAYPHTSL-QLPASQSALQ---SQQPPREQPLPPAPLAMPHIKPPPTT 934

Query: 239  PLPPLPSQQHHQQQS-LSGYSTLTWSS--PGLPSTQ--DNLIRNHTGSLAVANNNPTITV 293
            P+P LP+ Q H+    LSG S  + ++  P  P+ +   +L  +H  S            
Sbjct: 935  PIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS------------ 982

Query: 294  ADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQK 353
            A      +M   QP  SSP     L+     S    PP A+HP   +  V       Q  
Sbjct: 983  AHPPPLQLMPQSQPLPSSPAQPPGLT----QSQNLPPPPASHPPTGLHQVAPQPPFAQHP 1038

Query: 354  GVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGS 413
             V  G          P    STS           AG   +S     S    S  ++ GGS
Sbjct: 1039 FVPGGP-----PPITPPTCPSTSTPP--------AG-PGTSAQPPCSGAAASGGSIAGGS 1084

Query: 414  YPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQN 472
               + +      A D A EP+    P  + +P P V      A      Y  L  GY +
Sbjct: 1085 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 1143



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 61/294 (20%), Positives = 100/294 (34%), Gaps = 30/294 (10%)

Query: 303 QNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQY-GEYV 361
           + V+   SSP+ S        +S T      +        +++P+   + +G       V
Sbjct: 634 KKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSV 693

Query: 362 NNQASSAPTPLSS---TSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDML 418
           N++ SS P  +     ++       +D E+  DSS+        P +  A  G +     
Sbjct: 694 NDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS 753

Query: 419 SSSASSPAPDPAPEPDPASAPAPASAPAPVVP-QPSKMAKPFGYGYPTLQPGYQNATAPL 477
           +   +   P P P P   + P   S  A   P QP     P  + +    P         
Sbjct: 754 APPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAP--------- 804

Query: 478 ISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSL----------QSSPQPESLRPVNL 527
              + P  P       +P  +P +  L+ S G  S           Q  P P SL+   L
Sbjct: 805 --ALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL 862

Query: 528 TQERNILPMTPVWAPVPNLNADLKKLNCSP-DSFRCTLTNIPQTQALLNKAKLP 580
            Q     P  P   P P  +     L  SP  ++  T   +P +Q+ L   + P
Sbjct: 863 LQHPG--PPQPFGLP-PQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 72/323 (22%), Positives = 109/323 (33%), Gaps = 28/323 (8%)

Query: 263  SSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSS 322
            +SP +PS QD    N + S + A          +L  P      P  + P    + +   
Sbjct: 711  TSPSIPSPQD----NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP 766

Query: 323  GSSSTRTPPTANHPVEPVTSVTQ-PSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEE 381
              S+T  PP  +       +  Q P+  +    +Q    ++ Q   +P P    S     
Sbjct: 767  TPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPL 826

Query: 382  EEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAP 441
            +     AG    S  S A P       L G   P   S  A      P P P P   P  
Sbjct: 827  QPLTGSAG--QPSAPSHAQP------PLHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPPQ 877

Query: 442  AS-APAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPG 500
            AS   AP+   P+          P  Q   Q+   P    + P+ P+     + P   P 
Sbjct: 878  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPA-PLAMPHIKPPPTTP- 935

Query: 501  VNQLSSSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPDSF 560
            + QL +       Q+   P  L   +       LP  P   P+ +L+      +  P + 
Sbjct: 936  IPQLPAP------QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLST-----HHPPSAH 984

Query: 561  RCTLTNIPQTQALLNKAKLPLGL 583
               L  +PQ+Q L +    P GL
Sbjct: 985  PPPLQLMPQSQPLPSSPAQPPGL 1007


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 114/550 (20%), Positives = 200/550 (36%), Gaps = 69/550 (12%)

Query: 60    HHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSR 119
             HH++   PS   S G    +++P+ T           + T  VT +  ++      L + 
Sbjct: 10703 HHESDATPSIATSPGAETSSAIPIMTVS----PGAEDLVTSQVTSSGTDRNMTIPTL-TL 10757

Query: 120   GPPAPHIVGSTLGSFQGAASSA---SHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGF 176
              P  P  + S +   +   SSA   S +  + S+  +S V    +    +  +   S G 
Sbjct: 10758 SPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGE 10817

Query: 177   PSTCGHYAMSTVSNAAYPSVSYPSLP---------AGDTYGQMFTSQNAPTVRPVKDNSF 227
             P+T       TVS   +P+ + P++P           DT   M TS  A +   V   + 
Sbjct: 10818 PAT-------TVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTV 10870

Query: 228   SGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANN 287
             S +      P  + PL +       +     TL   SPG P T  ++  +H    + A  
Sbjct: 10871 STEV-----PGVVTPLVTSSRAVISTTIPILTL---SPGEPETTPSMATSHGEEASSAIP 10922

Query: 288   NPTITVADSLSCPVMQNVQPPKSSPVVST---VLSGSSGSSSTRTPPTANHPVEPVTSVT 344
              PT+    S   P +       S  V ST   +L+ S G   T      +H  E  ++V 
Sbjct: 10923 TPTV----SPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAV- 10977

Query: 345   QPSELLQQKGVQYGEYVNNQA---SSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASP 401
              P+ L +  G+      +++A   ++ PT   S  + E         G ++SST  + SP
Sbjct: 10978 -PTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSP 11036

Query: 402   --------MPNSYDALEGGSYPDML----------SSSASSPAPDPAPEPDPASAPAPAS 443
                     +  S   +   S P ++          S + S  A   +  P P  +P  + 
Sbjct: 11037 EVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSG 11096

Query: 444   APAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLIS--GVQPSNPVYSGFQQYPQQYPGV 501
                P+V   S+          TL       T  + +  GV+ S+ V +   + P     +
Sbjct: 11097 VVTPLVTS-SRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSL 11155

Query: 502   NQLSSSIGGLSLQ----SSPQPESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSP 557
                S ++   ++     SS +PE+   +    E  ++   P  A  P +   +  L  S 
Sbjct: 11156 VTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSS 11215

Query: 558   DSFRCTLTNI 567
              S     +N+
Sbjct: 11216 GSETSAFSNL 11225



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 123/579 (21%), Positives = 218/579 (37%), Gaps = 97/579 (16%)

Query: 2    SAPAGSSHPAASARIPPK------FGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPS 55
            ++PAG +H   ++ I P          A V+G++A +   A      ++    +  Q P+
Sbjct: 2522 TSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSE--ASLLTTSESKAIHSSPQTPT 2579

Query: 56   GYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQ 115
                        SG   +      SL + T+  D       + T  +  +TV+  P    
Sbjct: 2580 ---------TPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPP---- 2626

Query: 116  LYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNS-PAMYSASSSVASQ 174
              S+ P    + G+   SF         +  +A++P SS    ++S P +  AS S+ + 
Sbjct: 2627 --SKFPSTGTLSGA---SFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGT- 2680

Query: 175  GFPSTCGHYAMSTVSNA---AYPSVSYP--SLPA----GDTYGQMFTSQNAPT--VRPVK 223
              P T     MS  SN       +VS P  S+P     G T   +  S  +P+  V P +
Sbjct: 2681 -VPETT--LTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAP-R 2736

Query: 224  DNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLA 283
            + ++ G  T      P     S    Q    S  + L  SS GL     +++   TGS  
Sbjct: 2737 NTTYEGSITVALSTLPAGTTGSLVFSQSSENSETTALVDSSAGLERA--SVMPLTTGSQG 2794

Query: 284  VANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSV 343
            +A++    + +   +     +  P   +P   T +S  + +  T T  TA   + PV   
Sbjct: 2795 MASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAPKGI-PVKPT 2853

Query: 344  TQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMP 403
            +  S LL                   TP+S++S   +           S +T      +P
Sbjct: 2854 SAESGLL-------------------TPVSASSSPSK--------AFASLTTAPPTWGIP 2886

Query: 404  NSYDALEGGSYPDMLSSSASSPAP----DPAPEPDPASAPAPASAPAPVVPQPSKMAKPF 459
             S    E    P + + SAS P P    +  P+ D ++A +  S      P+   M    
Sbjct: 2887 QSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTK 2946

Query: 460  GYGYPTLQ-PGY----QNATAPLISGVQPSNPVY-SGFQQYPQQ---YPGVNQLSSSIGG 510
                 + Q  G+    + + +P ++G +P  P   +G  +Y  +   YP  ++ SS++  
Sbjct: 2947 AISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTS 3006

Query: 511  LSL-----------QSSPQPESLRPVNLTQERNILPMTP 538
             SL           Q++    S  P++L+ E+    ++P
Sbjct: 3007 TSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSP 3045



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 95/434 (21%), Positives = 172/434 (39%), Gaps = 63/434 (14%)

Query: 160  NSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTV 219
            ++   +S + S AS GF     H  M+T+ +     V +PSLP+ +    + +S ++P +
Sbjct: 8515 STTTFWSGTHSTASPGF----SHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSLSSPAM 8570

Query: 220  RPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYST--LTWSSPGLPSTQDNL--- 274
                  S   ++ + S P P+  L +    +   +   S+   T S P L ST   +   
Sbjct: 8571 TSTSFFSTLPESIS-SSPHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAEILAT 8629

Query: 275  --IRNHTGSLAVANNNPTITVAD------SLSCPVMQNVQPPKSSPVVST-VLSGSSGSS 325
              +      +  ++N P + V        S S  +   V    +SP+ +T  L  +S S+
Sbjct: 8630 SEVTKDREKIHPSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSVST 8689

Query: 326  STRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEED 385
            ST        P  P T +TQP+  L   G++  E   +Q +S+ T  S++          
Sbjct: 8690 ST--------PAFPETMMTQPTSSL-TSGLR--EISTSQETSSATERSASLSGMPTGATT 8738

Query: 386  EEAGVDSSSTTSSASPMPN--------SYDALEGGSYPDMLSSSASSPAPDPAPEPDPAS 437
            + +  ++ S   +++P P         S + +   S P   + SA            P +
Sbjct: 8739 KVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTI-------TPKT 8791

Query: 438  APAPASAPAPVVPQPSKMAK-PFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQ 496
              + AS+        S  A  P  +   T +  +   T P+  G +  +        +P 
Sbjct: 8792 GHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVS--------WPS 8843

Query: 497  QYPGVNQLS--SSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPV-----PNLNAD 549
            + P V + S  SS+  LS  +SP P    P + +   + L +T ++ PV       L+  
Sbjct: 8844 R-PSVEKTSPPSSLVSLSAVTSPSPLYSTP-SESSHSSPLRVTSLFTPVMMKTTDMLDTS 8901

Query: 550  LKKLNCSPDSFRCT 563
            L+ +  SP S   T
Sbjct: 8902 LEPVTTSPPSMNIT 8915



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 88/401 (21%), Positives = 157/401 (39%), Gaps = 44/401 (10%)

Query: 79   TSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQ-PGAQ--QLYSRGPPAPHIVGSTLGSFQ 135
            TS P  T    +     T P+  +T +T+ Q+ P ++   L SRG  A  +   +    +
Sbjct: 7330 TSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRG--AGDVPRPSSLPVE 7387

Query: 136  GAASSASHLHTSAS---QPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNA- 191
              +  +S L  SA     P SS +      + +S+S+SV S   P   G    + V +A 
Sbjct: 7388 ETSPPSSQLSLSAMISPSPVSSTL----PASSHSSSASVTSLLTP---GQVKTTEVLDAS 7440

Query: 192  AYPSVSYPSLPAGDTYGQMFTSQ---NAPTVRPVKDNSFSGQNTAIS-HPSPLPPLPSQQ 247
            A P  S P   +  +   + TS+   +   + P  + + +   T+ S H SP   LP  +
Sbjct: 7441 AEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSE 7500

Query: 248  HHQQQS------LSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPV 301
              +  S      + G ++++  +P L +T+   I++   S        T T ++  S   
Sbjct: 7501 TTKATSAMGTISIMGDTSVSTLTPALSNTRK--IQSEPASSLTTRLRETST-SEETSLAT 7557

Query: 302  MQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYV 361
              N    K S   +T +S +   S +RT            S++ P +    + +  G   
Sbjct: 7558 EANTVLSKVSTGATTEVSRTEAISFSRT------------SMSGPEQSTMSQDISIGTIP 7605

Query: 362  NNQASSAPTPLSS-TSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSS 420
               ASS  T  +  T   +    E       + +T ++ S +      ++G  +P+M +S
Sbjct: 7606 RISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTS 7665

Query: 421  SASSPAPDPAPEPDPASAPAPASAP--APVVPQPSKMAKPF 459
                P     P P      +P S+P   P V  P  ++  F
Sbjct: 7666 MGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTF 7706



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 94/451 (20%), Positives = 163/451 (36%), Gaps = 66/451 (14%)

Query: 58   GLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLY 117
            G+     I     +S G    +SLPL    G+  +A+  + T  +T        G     
Sbjct: 2794 GMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEV-TAMSEITTNRLTATQSTAPKGI---- 2848

Query: 118  SRGPPAPHIVGSTLGSFQGAASSASHLHTSASQ-------PYSSFVNHYNS-PAMYSASS 169
               P  P    S L +   A+SS S    S +        P S+    ++  P++ + S+
Sbjct: 2849 ---PVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSA 2905

Query: 170  SVASQGFPSTCGHYAMSTV--SNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSF 227
            S+ + G        +++T+  S+A+  S S    P  +   +M TS  A +    +   F
Sbjct: 2906 SLPTPG-------QSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGF 2958

Query: 228  SGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANN 287
            +      + PS         H  +   SG     ++S  +     +   +   S ++A+ 
Sbjct: 2959 TETPEGSASPS------MAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASK 3012

Query: 288  NPTI------TVADSLSCPVMQNVQPPKS--SPVVSTVLSGSS--GSSSTRTPPTANH-- 335
              T+        + S S P+  + +   S  SP  ST    S   G S  R P    H  
Sbjct: 3013 LTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQ 3072

Query: 336  ----PVEPVTSVT----QPSELLQQKGVQYGEYVNNQA-------SSAPT---PLSSTSD 377
                 + P +++     +P EL   + +   E    +        S  PT   P+SS ++
Sbjct: 3073 TSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTE 3132

Query: 378  DEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPAS 437
                 +   E    S S  +  S +  +   L   +   M S +A   +  PAP  +  S
Sbjct: 3133 PTARRKSSPETWASSISVPAKTSLVETTDGTLV--TTIKMSSQAAQGNSTWPAPAEETGS 3190

Query: 438  APAPASAPAPVVPQPSKMAKPFGYGYPTLQP 468
            +PA  S   P  P+ S   K      P++ P
Sbjct: 3191 SPAGTS---PGSPEMSTTLKIMSSKEPSISP 3218



 Score = 37.7 bits (86), Expect = 0.070
 Identities = 97/433 (22%), Positives = 159/433 (36%), Gaps = 76/433 (17%)

Query: 60  HHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYT--VPTQNVTPNTVNQQPGAQQLY 117
           HH      SG  ++G    +  PL+T      S +    VPT   T  T++ +  +    
Sbjct: 421 HHST----SGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFT--TLDSKIRSPSQV 474

Query: 118 SRGPPAPHIVGSTLGSFQGAASSASHLH---------TSASQPYSSFVNHYNSPAMYSAS 168
           S   P   +   T GS  G  SS++  H         TS++   SS+ +   +       
Sbjct: 475 SSSHPTREL--RTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQ 532

Query: 169 SSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFS 228
            +   +  PS       ++ S AA  + S PS+ +G T  +  +S     +     ++  
Sbjct: 533 HTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKT-SSTKGIWLEETSADTLI 591

Query: 229 GQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNN 288
           G++TA               HQ    +G S    SS        +L+   T S   +  +
Sbjct: 592 GESTA-----------GPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATAS---SETS 637

Query: 289 PTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSE 348
             +T+A         N  P   SP VS   +GSS    T+   T    V P TS  Q S 
Sbjct: 638 ADLTLAT--------NGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSA 689

Query: 349 LLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTT----SSASPMPN 404
              ++G   G           TPL++         E + AG    ST+    SSAS + +
Sbjct: 690 F--REGTSLG----------LTPLNTR--HPFSSPEPDSAGHTKISTSIPLLSSASVLED 735

Query: 405 SYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYP 464
              A    S+    +SS ++  P+ + +  P+SA   +   +     P ++         
Sbjct: 736 KVSATSTFSH-HKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERV--------- 785

Query: 465 TLQPGYQNATAPL 477
                 +NAT+PL
Sbjct: 786 ------RNATSPL 792



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 91/441 (20%), Positives = 152/441 (34%), Gaps = 60/441 (13%)

Query: 96   TVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSF 155
            TV  ++++P++V        L +  P +P    STLG+   + S+ +   T  +QP SS 
Sbjct: 8652 TVIYKHLSPSSV-----LADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSL 8706

Query: 156  VNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQN 215
             +     +    +SS   +            + S +  P+ +   +   +      TS  
Sbjct: 8707 TSGLREISTSQETSSATER------------SASLSGMPTGATTKVSRTEALSLGRTSTP 8754

Query: 216  APTVRPVKDNSFSGQNTAISHP------SPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPS 269
             P    +     +   T IS P      + +   P   H    S   ++  T S    P 
Sbjct: 8755 GPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPG 8814

Query: 270  TQDNLIRN--HTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSST 327
            T         H+G     +  P      S   P ++   PP S   +S V S S   S  
Sbjct: 8815 THSAATHRSPHSGMTTPMSRGPEDVSWPSR--PSVEKTSPPSSLVSLSAVTSPSPLYS-- 8870

Query: 328  RTPPTANH--PVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDE------ 379
             TP  ++H  P+  VTS+  P   +  K     +      +++P  ++ TSD+       
Sbjct: 8871 -TPSESSHSSPLR-VTSLFTP---VMMKTTDMLDTSLEPVTTSPPSMNITSDESLATSKA 8925

Query: 380  ----EEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDP 435
                E  +  E   V    T S+     +SY  L     P+   S  +SP    +   D 
Sbjct: 8926 TMETEAIQLSENTAVTQMGTISARQEFYSSYPGL-----PE--PSKVTSPVVTSSTIKDI 8978

Query: 436  ASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYP 495
             S   PAS+    +   S           T  P   + +  + S  +PS   Y       
Sbjct: 8979 VSTTIPASSEITRIEMESTSTL-------TPTPRETSTSQEIHSATKPSTVPYKALTSAT 9031

Query: 496  QQYPGVNQLSSSIGGLSLQSS 516
             +      +SSS G    QS+
Sbjct: 9032 IEDSMTQVMSSSRGPSPDQST 9052



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 67/302 (22%), Positives = 117/302 (38%), Gaps = 25/302 (8%)

Query: 79    TSLPLDTQCGDY-YSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGA 137
             TS P+      + +S+    P    +P T   +  +  L +  P AP +V S + S  GA
Sbjct: 11697 TSTPVSRTTSSFSHSSPDATPVMATSPRT---EASSAVLTTISPGAPEMVTSQITS-SGA 11752

Query: 138   ASSAS--HLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPS 195
             A+S +   L  S   P ++ +   + P   ++ +  AS  FP      A  T+   A  S
Sbjct: 11753 ATSTTVPTLTHSPGMPETTALLSTH-PRTETSKTFPASTVFPQVSETTASLTIRPGAETS 11811

Query: 196   VSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAIS-HPSPLPPLPSQQHHQQQSL 254
              + P+      +  + T  +   + P      S +   +S HP            +  ++
Sbjct: 11812 TALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGT----------ETSTM 11861

Query: 255   SGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVV 314
                STL   S GL  T   L  +   S   + +  T+TV+ ++S     ++   K   V 
Sbjct: 11862 IPTSTL---SLGLLETTGLLATS--SSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVT 11916

Query: 315   STVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSS 374
             S     +S S ++  PP  +  V   T    PSE+       +GE V+       T + +
Sbjct: 11917 SWNTE-TSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEA 11975

Query: 375   TS 376
             T+
Sbjct: 11976 TN 11977



 Score = 36.2 bits (82), Expect = 0.20
 Identities = 93/434 (21%), Positives = 160/434 (36%), Gaps = 48/434 (11%)

Query: 160  NSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTV 219
            +S A +  + S  +Q FP    H   +T  + +   VS+ S P+ +      +S ++P  
Sbjct: 5881 SSTASWEGTHSPVTQRFP----HSEETTTMSRSTKGVSWQSPPSVEET----SSPSSPVP 5932

Query: 220  RPVKDNSFSGQNTAISHPSPLPPLP------SQQHHQQQSLSGYSTLTWSS-PGLPSTQD 272
             P    S S   +A+S  SP   LP      S +      L  +S L  SS P   S   
Sbjct: 5933 LPAI-TSHSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSG 5991

Query: 273  NLIRN---------HTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSP--VVSTVLSGS 321
             ++ +         H        N  T      L   V  + QP   +P  V  +++  +
Sbjct: 5992 EILTSEASTNTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDA 6051

Query: 322  SGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEE 381
              S+ST   P   +     TS   P EL +         V N  + + T  SS S D   
Sbjct: 6052 IVSTSTPGSPETKNVDRDSTSPLTP-ELKEDSTA----LVMNSTTESNTVFSSVSLDAAT 6106

Query: 382  EEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAP 441
            E    E      +   +++    S D       P+  SS ++SP    +     A+   P
Sbjct: 6107 EVSRAEVTYYDPTFMPASAQSTKSPDIS-----PEASSSHSNSPPLTISTHKTIATQTGP 6161

Query: 442  ASAPA--PVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYP 499
            +   +   +    S +A   G      Q    + T  +++     N +    +  P    
Sbjct: 6162 SGVTSLGQLTLDTSTIATSAGTPSARTQDFVDSETTSVMN-----NDLNDVLKTSPFSAE 6216

Query: 500  GVNQLSSSIGGLSLQSSPQP--ESLRPVNLTQERNILPM-TPVWAPVPNLNADLKKLNCS 556
              N LSS    L + +SP P   +L+  + +   ++  + TP  A + +++ +L+ +  S
Sbjct: 6217 EANSLSSQ-APLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRS 6275

Query: 557  PDSFRCTLTNIPQT 570
            P + R TL     T
Sbjct: 6276 PQNLRNTLATSEAT 6289



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 125/657 (19%), Positives = 215/657 (32%), Gaps = 116/657 (17%)

Query: 2    SAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHH 61
            +AP  ++ P  S R       A  + + +     A     +   PA + M+  S   +  
Sbjct: 960  AAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATS---IRE 1016

Query: 62   QNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGP 121
             +    +   + GPG M     +   G  Y     + T ++   T      +        
Sbjct: 1017 PSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSETSMDFTM--- 1073

Query: 122  PAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCG 181
             A   V  ++   Q   ++ S      SQ    FV+ ++    +  S  +     P    
Sbjct: 1074 -AKESVSMSVSPSQSMDAAGSSTPGRTSQ----FVDTFSDDVYHLTSREIT---IPRDGT 1125

Query: 182  HYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLP 241
              A++    A +P    P        G + +S ++PT +    ++FS Q    S      
Sbjct: 1126 SSALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTS------ 1179

Query: 242  PLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNN--PTITVADSLSC 299
                        +    T  W+ P LPST      N   S A+  +   P  T + + S 
Sbjct: 1180 ----------MIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSPATSL 1229

Query: 300  PVMQNVQP-----PKSSPVVSTVLSGSSGSSSTRT-PPTANHPVEP--VTSVTQPS---- 347
               +   P     P+S+   S  L   + S S  T   T    V+P   T +T PS    
Sbjct: 1230 EASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETH 1289

Query: 348  ------ELLQQKG-----VQYGEYVNNQASSAPTPLSSTSD--DEEEEEEDEEAGVDSSS 394
                   +    G        GE  N  ++  PT   +T+D  D    +      V +  
Sbjct: 1290 IHVSTARMAYSSGSSPEMTAPGE-TNTGSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLR 1348

Query: 395  TTSSASPMPNSYDALEGGSYPDMLSSSASSPA---------------------PDPAPEP 433
            TT +     ++  A   GS     S + +SPA                      + +   
Sbjct: 1349 TTENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGF 1408

Query: 434  DPASAPAPASAPAPVVPQPSKMAKPFGYGYP----TLQPGYQNA-TAPLISGV------- 481
            +  SAP P S   P  P             P     L P  Q   T P+ + +       
Sbjct: 1409 ETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEE 1468

Query: 482  ---------QPSNPVYSGFQQYPQQYPGVNQLS------SSIGGLSLQSSPQPESLRPVN 526
                      PS+P+ S F  +P      ++LS      S+I      +  Q   +R + 
Sbjct: 1469 MASTDLDISSPSSPM-STFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLG 1527

Query: 527  LTQERNILPMTPV---WAPVPNLNADLKKLNCSPDSFRCTLTNIPQTQALLNKAKLP 580
             T +   +P+TP+   W  V      ++    + D+   T++    TQ+L ++  +P
Sbjct: 1528 RTGDLTTVPITPLTTTWTSV------IEHSTQAQDTLSATMSPTHVTQSLKDQTSIP 1578



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 74/327 (22%), Positives = 119/327 (36%), Gaps = 39/327 (11%)

Query: 130  TLGSFQGAASS--ASHLHTSASQPY--SSFVNHYNSPAMYSASSSVASQGFPSTCGHYAM 185
            T  S  G+ SS  A    T A+ P   +S + H       S SS        ST      
Sbjct: 6893 TTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKREST-----Y 6947

Query: 186  STVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPS 245
            S        S+S  +  + DT   +       T    +    S   T+I  PS    LP 
Sbjct: 6948 SLTPGLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPE 7007

Query: 246  QQHHQQQSLSGYSTLTWSS---------PGLPSTQDNLIRNHTGSLAVANNNPTITVA-- 294
                    L    T+T S+         P   ++QD L  + + + + A  + T+T    
Sbjct: 7008 ISTRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFP 7067

Query: 295  ------------DSLSCPVMQNVQPPKSSP-VVSTVLSGSSGSSSTRTPPTANHPVEPVT 341
                          +S     +++ P S P ++S   + S    S+  P T +    PVT
Sbjct: 7068 HSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVT 7127

Query: 342  SVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDE---EAGVDSSSTTSS 398
            S+   S +     +     +    +S+P  LS TSD+     +D    EA   S++T +S
Sbjct: 7128 SLLTSSPVTTTDMLHTSPEL---VTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAAS 7184

Query: 399  ASPMPNSYDALEGGSYPDMLSSSASSP 425
               +P+S       +  D  +S A+SP
Sbjct: 7185 NVEIPSSGHESPSSALADSETSKATSP 7211



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 99/466 (21%), Positives = 160/466 (34%), Gaps = 58/466 (12%)

Query: 118   SRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFP 177
             S GP A   V +T  S   +    S + +S +   ++F     +P  Y   ++      P
Sbjct: 11524 SPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETP--YEPETTATWLTHP 11581

Query: 178   STCGHYAMSTVSNAAYP-SVSYPSL---PAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTA 233
             +        T+ N ++  S + PS+   P  DT   + T+   P++  V  +  +   T 
Sbjct: 11582 AETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATD 11641

Query: 234   ISHPSP-LPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTIT 292
              S   P L P P           G    T SS   P TQ       TG        P+ +
Sbjct: 11642 TSTAIPTLTPSP-----------GEPETTASSATHPGTQ-------TGFTVPIRTVPS-S 11682

Query: 293   VADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQ 352
               D+++  V     PP++S  VS   S  S SS   TP  A  P    +S      +L  
Sbjct: 11683 EPDTMASWV---THPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSA-----VLTT 11734

Query: 353   KGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGG 412
                   E V +Q +S+    S+T             G+  ++   S  P   +       
Sbjct: 11735 ISPGAPEMVTSQITSSGAATSTT-----VPTLTHSPGMPETTALLSTHPRTETSKTFPAS 11789

Query: 413   SYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQN 472
             +    +S + +S    P  E   A      S+   ++   +          PT  PG   
Sbjct: 11790 TVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGTSRVDL----SPTASPGVSA 11845

Query: 473   ATAPL-------ISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSSPQPESLRPV 525
              TAPL        S + P++ +  G  +        +   +S   L+L  SP    L   
Sbjct: 11846 KTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSA 11905

Query: 526   NLTQERNILPMTPV-WAPVPNLNADLKKLNCSPDSFRCTLTNIPQT 570
             ++T ++   P T   W    N        +  P  F  T+T    T
Sbjct: 11906 SITTDK---PQTVTSW----NTETSPSVTSVGPPEFSRTVTGTTMT 11944



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 75/363 (20%), Positives = 127/363 (34%), Gaps = 53/363 (14%)

Query: 93   ALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLG-SFQGAASSASHLHTSASQP 151
            A+ + P  +  P T++  P    + S   P+  +   TLG S +   SS  +L +++ + 
Sbjct: 6810 AMTSPPVSSTLPKTIHTTPSP--MTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEI 6867

Query: 152  YSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMF 211
             ++  +     AM+ ++S+ A+    ++ GH + S+V   +  + +   +    T G   
Sbjct: 6868 LTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTT 6927

Query: 212  TSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQ 271
             S +          S S + T I   S     P  +       + +ST T          
Sbjct: 6928 VSTSM---------SVSSETTKIKRESTYSLTPGLRETSISQNASFSTDT---------- 6968

Query: 272  DNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTR--T 329
                        V +  PT T A+     V  + +     P  STVL   S  + TR   
Sbjct: 6969 ----------SIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFA 7018

Query: 330  PPTANHPVE-PVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEA 388
             PT     E  + + T PS    Q  +          +   + L+      E        
Sbjct: 7019 SPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSE-------- 7070

Query: 389  GVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAP---ASAP 445
                 +T  S  P   S+ +      P  L S  S PA      P P S+  P   +S+P
Sbjct: 7071 ----MTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPA---TTSPPPISSTLPVTISSSP 7123

Query: 446  APV 448
             PV
Sbjct: 7124 LPV 7126



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 51/225 (22%), Positives = 86/225 (38%), Gaps = 34/225 (15%)

Query: 183  YAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPP 242
            +A  T++ +A  ++   + P+G T     T   + T    K +S   Q    S  + L  
Sbjct: 7017 FASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLMS 7076

Query: 243  LPSQQHHQQQSLSGYSTLTW-SSPGL--PSTQDNLIRNHTGSLAVANNNPTI--TVADSL 297
                         G   ++W SSP L  PS+  +L+     SL    + P I  T+  ++
Sbjct: 7077 ------------RGPGDMSWQSSPSLENPSSLPSLL-----SLPATTSPPPISSTLPVTI 7119

Query: 298  SCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQY 357
            S   +       SSPV +T +  +S    T +PP  +H        T    L   K    
Sbjct: 7120 SSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSH--------TSDERLTTGKDTTN 7171

Query: 358  GEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPM 402
             E V+   ++A    +S  +      E   + +  S T+ + SPM
Sbjct: 7172 TEAVHPSTNTA----ASNVEIPSSGHESPSSALADSETSKATSPM 7212



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 92/463 (19%), Positives = 149/463 (32%), Gaps = 58/463 (12%)

Query: 7   SSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGL---HHQN 63
           SSHP    R      G   S  AA        A       A +     +        H  
Sbjct: 476 SSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQ 535

Query: 64  YIAPSGHY-SQGPGKMTSL--PLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSR- 119
           ++  S    ++ P   TS+  P+ T      S   T+ T + T     ++  A  L    
Sbjct: 536 WVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSS-TKGIWLEETSADTLIGES 594

Query: 120 --GPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFP 177
             GP        T  S  G +S      T  SQ  +  +    + +  SA  ++A+ G P
Sbjct: 595 TAGPTTHQFAVPTGISMTGGSS------TRGSQGTTHLLTRATASSETSADLTLATNGVP 648

Query: 178 STCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHP 237
            +       T + ++ P  + PS     +     +S  +   R       +  NT     
Sbjct: 649 VSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFS 708

Query: 238 SPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPST---QDNLIRNHTGSLAVANNNPTITVA 294
           SP P             +G++ ++ S P L S    +D +    T S   A ++ T    
Sbjct: 709 SPEP-----------DSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITT--- 754

Query: 295 DSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKG 354
                           +P +ST    SS   S+ T   A    E V + T P       G
Sbjct: 755 ---------------GTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHPSPSG 799

Query: 355 VQYGEYVNNQASSAPT-------PLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYD 407
            +    V   ++SA T       P  + + +  E          S   T+ +S  P+++ 
Sbjct: 800 EETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHL 859

Query: 408 ALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVP 450
              G    +  + S S P    +      +  A  S P PV P
Sbjct: 860 FTSGEETEETSNPSVSQPETSVS---RVRTTLASTSVPTPVFP 899



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 37/195 (18%), Positives = 70/195 (35%), Gaps = 10/195 (5%)

Query: 214  QNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDN 273
            Q+   +  V     S Q  +  + + +    S  H    S    ++  +SS  L S    
Sbjct: 1982 QSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDST 2041

Query: 274  LIRNH---------TGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGS 324
            + R +         T SL      P+ +++++LS        P  ++       + S+ +
Sbjct: 2042 ISRRNAITSWLWDLTTSLPTTTW-PSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSA 2100

Query: 325  SSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEE 384
            +  R P T  H  +   + T  ++     G+       + +S  P P++ TS  +     
Sbjct: 2101 AKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLT 2160

Query: 385  DEEAGVDSSSTTSSA 399
             E     S  T SSA
Sbjct: 2161 SESTANPSLGTASSA 2175



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 72/315 (22%), Positives = 116/315 (36%), Gaps = 57/315 (18%)

Query: 102  VTPNTVNQQPGA----QQLYSRGPPAPH--------IVGSTLGSFQGAASSASHLHTSAS 149
            ++ NT   Q G     Q+ YS  P  P         +  ST+         AS   T   
Sbjct: 8934 LSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITRIE 8993

Query: 150  QPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMS--TVSNAAYPSVSYPSLPAGDTY 207
               +S +    +P   S S  + S   PST  + A++  T+ ++    +S    P+ D  
Sbjct: 8994 MESTSTLTP--TPRETSTSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPD-- 9049

Query: 208  GQMFTSQNAPT-------VRPVKDNSFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTL 260
             Q   SQ+  T         P+K  S       I+  +  P   S+      + + + + 
Sbjct: 9050 -QSTMSQDISTEVITRLSTSPIKTES---TEMTITTQTGSPGATSRGTLTLDTSTTFMSG 9105

Query: 261  TWS--SPGLPSTQDNLIRNHTGSLAVANNNPTITVADS----LSCPVMQNVQPPKSS--- 311
            T S  S G   +Q   + + T       ++P++  A S    LS PVM +  P  S+   
Sbjct: 9106 THSTASQGFSHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPD 9165

Query: 312  -------PVVS---------TVLSGSSGSSSTRTPP---TANHPVEPVTSVTQPSELLQQ 352
                   PV S         T L G+S    T +PP   + +  +  +T VT  +E L+ 
Sbjct: 9166 SIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEKLEM 9225

Query: 353  KGVQYGEYVNNQASS 367
              V    Y +   SS
Sbjct: 9226 TNVVTSGYTHESPSS 9240



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 78/350 (22%), Positives = 129/350 (36%), Gaps = 72/350 (20%)

Query: 138  ASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQG-----------------FPSTC 180
            A SAS  H ++    SS  + Y+S ++ S  S+++ +                  +PST 
Sbjct: 2009 AVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTWPSTS 2068

Query: 181  GHYAMST----VSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISH 236
               A+S+    VSN +  +  +P   A  T      +    T  P ++ + S  NT  S 
Sbjct: 2069 LSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGP-QNTAASTLNTDASS 2127

Query: 237  PSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADS 296
             + L   P        S+S    L  +   + S  D      +G  + +  NP++  A S
Sbjct: 2128 VTGLSETP-----VGASISSEVPLPMA---ITSRSD-----VSGLTSESTANPSLGTASS 2174

Query: 297  LSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVE------PVTSVTQPSELL 350
                + + +  P S  +VS  ++    + S    P  +HP        PV S   P   L
Sbjct: 2175 AGTKLTRTISLPTSESLVSFRMNKDPWTVSI---PLGSHPTTNTETSIPVNSAGPPG--L 2229

Query: 351  QQKGVQYGEYVNNQASSAPTPLSSTSDDEE-------EEEEDEEAGVDSSST---TSSAS 400
                    +  ++ A S PT   S S D E        E+        SS T   TS  +
Sbjct: 2230 STVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVT 2289

Query: 401  PMPNSYDALEGGSYPDMLSSSASSPAPDPAP-----EPDPASAPAPASAP 445
            P+P            D +SS+ S+     +P     E    ++ AP ++P
Sbjct: 2290 PIPG-----------DWMSSAMSTKPTGASPSITLGERRTITSAAPTTSP 2328



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 50/237 (21%), Positives = 88/237 (37%), Gaps = 31/237 (13%)

Query: 167  ASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNS 226
            +SS +A     S     A++ +SN    + S   + A  T     TS +APT+      S
Sbjct: 4058 SSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSATAS 4117

Query: 227  FSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVAN 286
            ++G        +PL       + ++ +L        S P  PS ++    + + SL   +
Sbjct: 4118 WTG--------TPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEET---SSSSSLVPIH 4166

Query: 287  NNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQP 346
                 T + S      Q   P  + PV S  LS +SG   T                T  
Sbjct: 4167 ----ATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKT----------------TDM 4206

Query: 347  SELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMP 403
            S +  + G      +++ A  A +   ++ D +      + A  +  +T+S  SP+P
Sbjct: 4207 SRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIP 4263



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 36/152 (23%), Positives = 64/152 (42%), Gaps = 9/152 (5%)

Query: 278  HTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPV 337
            H+    V N +P I     LS  +  +++    S  +    + +S   S+  P T +   
Sbjct: 6774 HSEMTTVMNKDPEI-----LSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTP 6828

Query: 338  EPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTS 397
             P+TS+  PS ++    +          +S+P  LSSTS +    +ED  A      +TS
Sbjct: 6829 SPMTSLLTPSLVMTTDTLGTSP---EPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTS 6885

Query: 398  SASPMPNSYDALEGGSYPDMLSSSASSPAPDP 429
            +A+    +  +   GS   +L+ S  + A  P
Sbjct: 6886 TAATNVETTSS-GHGSQSSVLADSEKTKATAP 6916



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 25/98 (25%), Positives = 37/98 (37%), Gaps = 4/98 (4%)

Query: 307  PPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQY----GEYVN 362
            P  S PV   + +G +      + P  + P+ P T V   +  ++Q          E V+
Sbjct: 1937 PFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVS 1996

Query: 363  NQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSAS 400
             Q  S P   S         E    +G  +SS  SSAS
Sbjct: 1997 VQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSAS 2034


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 116/530 (21%), Positives = 164/530 (30%), Gaps = 96/530 (18%)

Query: 3    APAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQ 62
            +P G+  P A+    PK G A  S   AP  P A P P  + GPA      PS  G    
Sbjct: 935  SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP-PSPKGGPA-----TPSPKG---- 984

Query: 63   NYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPP 122
               AP+   +  P         +  G       T P+   +P       GA    +  PP
Sbjct: 985  ---APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041

Query: 123  APHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGH 182
            +P          +G+ ++                    +P    A ++ A+   PS  G 
Sbjct: 1042 SP----------KGSPAA--------------------TPLPKGAPTTPAAT-LPSPKGG 1070

Query: 183  YAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPP 242
             A  ++  A  P  + P  P G   G    S     + P           A + PSP   
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKG---GPATPSPKGAPMPP-----------AATPPSPKGG 1116

Query: 243  LPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVA--NNNPTITVADSLSCP 300
            L +  H                 G P+T      +  G LA       PT   A   S  
Sbjct: 1117 LATPPHK----------------GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK 1160

Query: 301  VMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGEY 360
                  PPK +P      +  S      TP     P  P  +   P   L     +    
Sbjct: 1161 GGLATPPPKGAPTTPAA-TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP- 1218

Query: 361  VNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSS 420
                A++ P+P    +    +      A    S     A+P P         + P +   
Sbjct: 1219 -TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277

Query: 421  SASSP---APDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPL 477
             A+ P   AP+PA    P+    PA++P    P P     P   G P   P     T P 
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337

Query: 478  ISGVQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSLQSS---PQPESLRP 524
            ++   P      G    P   P      SS GG +  SS   P P +  P
Sbjct: 1338 VTPPSP-----KGTPTLPATTP------SSKGGPTTPSSKEGPTPPAATP 1376



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 106/508 (20%), Positives = 158/508 (31%), Gaps = 99/508 (19%)

Query: 17   PPKFGGAAVSGAAAPAGPGAGPA-PHQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGP 75
            PPK  GA  + AA P  P  G A P  +  P       PS  G        PS      P
Sbjct: 1167 PPK--GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG----GLATPSP--KGAP 1218

Query: 76   GKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPP---APHIVGSTLG 132
                + P   + G         P+    P T    P + +     PP   AP    +T  
Sbjct: 1219 TTPAATPPSPKGG------LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPP 1272

Query: 133  SFQGAASSASHL---HTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVS 189
            S +G  ++  H    + +   P S       SP   + +   A+   PS  G        
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP--PSPKGSPGTPPPK 1330

Query: 190  NAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLPSQQHH 249
             A  P    P  P G            PT+     +S  G  T  S   P PP  +  H 
Sbjct: 1331 GAPTPPAVTPPSPKG-----------TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379

Query: 250  QQQSLSGYSTLTW---------------------SSPGLPSTQDNLIRNHTGSLAVANNN 288
               +++  S                          +P  P T++       G L      
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439

Query: 289  PTI--------------TVADSLSCPVMQNVQPP--KSSPVVSTVLSGSSGSSSTRTPPT 332
            P                    S   P +  V PP  K  P    V + SS   +  TP  
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499

Query: 333  ANHPVEPVTSVTQPSE-----------------LLQQKG---VQYGEYVNNQASSAPTPL 372
               P  P    + P E                 LL +K    +   E +   A + P+P 
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK 1559

Query: 373  SSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPD--MLSSSASSPAPDPA 430
             + +    +E     A   S   +S  +  P++Y   +G   P   ++  + +SP+P  A
Sbjct: 1560 KTPAIPTPKEAP---ATPSSKEASSPPAVTPSTY---KGAPSPKELLIPPAVTSPSPKEA 1613

Query: 431  PEPDPASAPAPASAPAPVVPQPSKMAKP 458
            P P   + P+P   PA   P+ +  + P
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTPTSPP 1641



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 97/427 (22%), Positives = 168/427 (39%), Gaps = 52/427 (12%)

Query: 96  TVPTQNVTPNTVNQQPGAQQLYSRGPP------APHIVGSTLGSFQGAASSASHLHTSA- 148
           TVP   VTP   + Q G   L    P       +P +  +T+ S   +  +   L     
Sbjct: 211 TVPYHCVTP-MASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGP 269

Query: 149 -SQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTY 207
            S P +  ++  + P + S+  +      P+T   + +S  S+ A   +   S  +    
Sbjct: 270 VSPPAALSLSTQSLPVVTSSQKTAG----PNTPPDFPISLGSHLA--PLHQSSFGSVQLL 323

Query: 208 GQMFTSQNAPTVRPVKDNSFSGQNTAISHPSP---LPPLPSQQHHQQQSLSGYSTLTWSS 264
           GQ  T  +A +   VK  S    +T  S+PS    +PPLPS+      +++ +  +  S 
Sbjct: 324 GQ--TGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSV 381

Query: 265 PGLPSTQDNLIRNHTGSLAVANN---NPTITVADSLSCPVMQN----VQPPKSS----PV 313
              PST  ++  + +GSL VA +   +PT ++    S     +     Q P SS    P+
Sbjct: 382 DKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPL 441

Query: 314 VSTVLSGSSGSSSTR-------TPPTANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQAS 366
           V T     + + +T        +PP ++ P+  +   T P+ L+    V   E     A+
Sbjct: 442 VVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNI-EPTSPAALVMAP-VAPKEPSTQVAT 499

Query: 367 SAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASS-- 424
           +   P+S    D E+ +    + +    T      +P S   LEG  +    +   +   
Sbjct: 500 TLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPAS---LEGAPFSPAQAGLTTKKD 556

Query: 425 ----PAPDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISG 480
               P    AP+  P+     +S   P+ P+ +   K  G   P  +P   + T+PL  G
Sbjct: 557 PTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPA-SSMTSPL--G 613

Query: 481 VQPSNPV 487
           V  S  V
Sbjct: 614 VNSSASV 620



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 98/423 (23%), Positives = 137/423 (32%), Gaps = 70/423 (16%)

Query: 145  HTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAG 204
            HTSA  P +S  +    P   S +S+ AS     T    + S +  +  P    P    G
Sbjct: 756  HTSALAPVAS--SPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKG 813

Query: 205  DTYGQMFTSQNAPTVRPVK-----DNSFSGQNT----AISHPSPLPPLPSQQHHQQQSLS 255
                       +  V PV+     +NS S Q +    A +H SP PP P           
Sbjct: 814  SAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH-SPTPPSPK---------- 862

Query: 256  GYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQP-PKSSPVV 314
                      G P+       +  G        PT +V + L  P      P PK +P +
Sbjct: 863  ----------GAPTPSAVTPLSPKGVTLPPKETPTPSVVN-LPFPKEGPATPAPKQAPAL 911

Query: 315  STVLSGSSGSSSTRTPPTANHPVEPVT-------SVTQPSELLQQKGVQYGEYVNNQASS 367
            S  ++ SS   +  TP     P  P         + T PS                 A++
Sbjct: 912  S--MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969

Query: 368  APTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAP 427
             P+P    +    +      A    S     A+P P         + P    S A++P P
Sbjct: 970  PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP 1029

Query: 428  DPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPV 487
              A  P  A+ P+P  +PA         A P   G PT       AT P   G  P+ P 
Sbjct: 1030 KGASTPPAATPPSPKGSPA---------ATPLPKGAPTTPA----ATLPSPKG-GPATPS 1075

Query: 488  YSGFQQYPQQYPGVNQLSSSIGGLSLQS---SPQPESLRPVN-----LTQERNILPMTPV 539
              G    P   P      S  GG +  S   +P P +  P +      T      P TP 
Sbjct: 1076 LKGAPTPPAATP-----PSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130

Query: 540  WAP 542
              P
Sbjct: 1131 ATP 1133



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 99/478 (20%), Positives = 162/478 (33%), Gaps = 41/478 (8%)

Query: 6    GSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPA-PHQQNGPAQNQMQVPSGYGLHHQNY 64
            G++ P+     PP     ++  A A + P  GPA P  +  P    +  PS         
Sbjct: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483

Query: 65   IAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAP 124
            +A S    + P   T  P+            T+P   V P++  + P A     R P AP
Sbjct: 1484 VATSSSPKKAPA--TPAPMGAP---------TLPA--VIPSSPKEVP-ATPSSRRDPIAP 1529

Query: 125  HIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYA 184
                +TL S +  A+ A     +   P  +  +   +PA+ +   + A+          A
Sbjct: 1530 T---ATLLSKKTPATLAPK--EALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA 1584

Query: 185  MSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHPSPLPPLP 244
            ++  +    PS     +P   T      +   P V P               P+  P  P
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644

Query: 245  SQQHHQQQSLSGYS-----TLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSC 299
            S       S +  +     T+  +S GLP+ +               + P IT       
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITA------ 1698

Query: 300  PVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKGVQYGE 359
            P  +  Q  KSS     +    S  + ++ P +   P   +      S+  + K   +  
Sbjct: 1699 PTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSP 1758

Query: 360  Y--VNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPM-PNSYDALEGG---- 412
               +    S A TPL++ +  E+   + E A V ++ +   + P+ P+    L       
Sbjct: 1759 KGPLAPPESKASTPLTAAAF-EKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFL 1817

Query: 413  -SYPDMLSSSASSP-APDPAPEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQP 468
             S P ++  S S P AP    E  P   P P S   P       M  P   G P   P
Sbjct: 1818 PSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTP 1875



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 124/587 (21%), Positives = 181/587 (30%), Gaps = 89/587 (15%)

Query: 2    SAPAGSSHPAASARIPPKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQN-----------Q 50
            S P+ S  PA +     K  G + + A AP        P + +G +              
Sbjct: 733  SVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD 792

Query: 51   MQVPSGYGLHHQNYIAPSGHYSQGP----GKMTS---------LPLDT--------QCGD 89
               P G  +  Q    P+   S GP    G ++S         LP ++            
Sbjct: 793  SPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPAT 852

Query: 90   YYSALYTVPTQNVTPNTVNQ-QPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSA 148
             +S     P    TP+ V    P    L  +  P P +V       +G A+ A     + 
Sbjct: 853  THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK-EGPATPAPKQAPAL 911

Query: 149  SQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDT-- 206
            S   SS      +PA     +S + +G P+       S     A PS  +   P   T  
Sbjct: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971

Query: 207  --YGQMFT--SQNAPTVRPVKDNSFSG------QNTAISHPSPLPPLPSQQHHQQQSLSG 256
               G   T   + APT       S  G         A + P+  PP P           G
Sbjct: 972  SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031

Query: 257  YSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVST 316
             ST   ++P  P       +    +  +    PT T A +L  P      P         
Sbjct: 1032 ASTPPAATPPSP-------KGSPAATPLPKGAPT-TPAATLPSPKGGPATPSLKGAPTPP 1083

Query: 317  VLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELL---QQKGVQYGEYVNNQASSAPTPLS 373
              +  S      TP     P+ P  +   P   L     KG          A++ P+P  
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP-----TTPAATPPSPKG 1138

Query: 374  STSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEP 433
              +    +      A    S     A+P P         + P       ++P+P  AP  
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT-PPSPKGGLATPSPKGAPTT 1197

Query: 434  DPASAPAP------------ASAPAPVVPQP-SKMAKPFGYGYPTLQPGYQNATAPLISG 480
              A+ P+P             + PA   P P   +A P   G PT       AT P   G
Sbjct: 1198 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA----ATPPSPKG 1253

Query: 481  VQPSNPVYSGFQQYPQQYPGVNQLSSSIGGLSL---QSSPQPESLRP 524
              P+ P   G    P   P      S  GGL+    + +P P  + P
Sbjct: 1254 -GPATPPPKGAPTPPAATP-----PSLKGGLATPPHKGAPNPAVVTP 1294



 Score = 34.7 bits (78), Expect = 0.59
 Identities = 122/579 (21%), Positives = 189/579 (32%), Gaps = 97/579 (16%)

Query: 1    MSAPAGSSHPAASARIPPKFGGAAV-SGAAAPAGPGAGPA---------PHQQNGPAQNQ 50
            ++ P+    P   A  P   GG    S    P  P A P+         P  + GPA   
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA--- 1394

Query: 51   MQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQ 110
              +PS  G      + P       P K  + P+ T+ G    +   +    VTP ++ + 
Sbjct: 1395 --IPSPKGDPTSPAVIPLS-----PKKAPATPV-TREGAATPSKGDLTPPAVTPVSLKKA 1446

Query: 111  PGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSS 170
            P A      GP  P   G        A +  S     A +  ++  +   +PA      +
Sbjct: 1447 P-ATSAPKGGPATPSSKGDPT---LPAVTPPSPKEPPAPKQVATSSSPKKAPA------T 1496

Query: 171  VASQGFPSTCGHYAMSTVSNAAYPSVSY-PSLPAGDTYGQMFTSQNAPT---VRPVKDNS 226
             A  G P+       S     A PS    P  P      +   +  AP    + P     
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556

Query: 227  FSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVAN 286
               +  AI  P   P  PS +          ST      G PS ++ LI           
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK----GAPSPKELLIP---------- 1602

Query: 287  NNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTA-NHPVEPVTSVTQ 345
              P +T       P    V PP      +T     + +S   TP +  + P  P +   +
Sbjct: 1603 --PAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660

Query: 346  PSELLQQ--KGV--QYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASP 401
                + Q  KG+  + G     +   AP P S+        +  +     SS+T+    P
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTK--KSSATSPPICP 1718

Query: 402  MPNSYDALEG----------------GSYPDMLSSSASSPAPDPAPEPDPASAPAPASAP 445
             P++ +  +G                 S       ++ SP    AP    AS P  A+A 
Sbjct: 1719 DPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF 1778

Query: 446  APVVPQPSKMAKPFGYGYPTLQPGYQNATAPLISGVQPSNPVYSGFQQYPQQYPGVNQLS 505
              V+P+P   +       P         + PL     P+ P        P+Q     Q  
Sbjct: 1779 EKVLPKPESASVSAAPSPP--------VSLPLAPSPVPTLP--------PKQ-----QFL 1817

Query: 506  SSIGGLSLQSSPQPESLRPVNLTQERNILPMTPVWAPVP 544
             S  GL L+S  +P  L P +  +   ++P  P+   VP
Sbjct: 1818 PSSPGLVLESPSKP--LAPADEDELLPLIPPEPISGGVP 1854


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 104/495 (21%), Positives = 167/495 (33%), Gaps = 63/495 (12%)

Query: 41   HQQNGPAQNQMQVPSGYGLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQ 100
            H Q+G  + Q    +    H+Q  + PS   S  PG       +    +Y+     V   
Sbjct: 1137 HTQDGHGEYQYTQEANCTWHYQPCLCPSQPQSV-PGSNIEGCYNCSQDEYFDHEEGVCVP 1195

Query: 101  NVTPNTVNQQPGAQQLYSRGPPAPHI-----VGSTLGSFQGAASSASHLHTSASQPYSSF 155
             + P T  Q P   QL + G     +       +T+G       S S  HT AS   +  
Sbjct: 1196 CMPPTTP-QPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPL 1254

Query: 156  VNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQN 215
            +     PA  ++S   AS G P           ++   P+ +  S     T  Q  T   
Sbjct: 1255 L-----PATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRAT 1309

Query: 216  APTVRPVKDNSF-SGQNTAISHPSPL-----PPLPSQQHHQQQSLSGYSTL--------- 260
            A T  P   ++  S   T ++ P+P      P LP   + +    +   T          
Sbjct: 1310 ASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPAST 1369

Query: 261  ---TWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTV 317
               T   PG P+           +        T T   +   P   +  P   SPV ST 
Sbjct: 1370 TGPTTPQPGQPTRP---------TATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTG 1420

Query: 318  LSGSSGSSSTRTPPTANHP-------VEPV-TSVTQPS--ELLQQKGVQYGEYVNNQASS 367
               ++   +T T PT +HP       V P  TS+  PS   ++     Q     +N ++ 
Sbjct: 1421 PVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAP 1480

Query: 368  A-----PTPLSST-SDDEEEEEEDEEAGVDSSSTTSSASPMPNS-YDALEGGSYPDMLSS 420
                  PT L +T S           +G   + ++ S +  P S +       +P++  +
Sbjct: 1481 TGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPT 1540

Query: 421  SASSPAPDP------APEPDPASAPAPASAPAPVVPQPSKMAKPFGYGYPTLQPGYQNAT 474
            S ++  P+P       P     SA +    P      P   + PF    P     ++  T
Sbjct: 1541 STTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTT 1600

Query: 475  A-PLISGVQPSNPVY 488
              P  S  Q + P +
Sbjct: 1601 TYPTPSHPQTTLPTH 1615



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 80/335 (23%), Positives = 113/335 (33%), Gaps = 68/335 (20%)

Query: 10   PAASARIP--PKFGGAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGYGLHHQNYIAP 67
            PA S   P  PK     + G  A    G  P P    GP   Q                 
Sbjct: 1334 PATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQ----------------- 1376

Query: 68   SGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIV 127
                   PG+ T            +  YT P    TP+T +  P A      G P P   
Sbjct: 1377 -------PGQPTRPTATETTQTRTTTEYTTPQ---TPHTTHSPPTA------GSPVPSTG 1420

Query: 128  GSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFPSTCGHYAMST 187
              T  SF      A+  + + S P ++   H      +S S    S     T  H  M+T
Sbjct: 1421 PVTATSFH-----ATTTYPTPSHPETTLPTHV---PPFSTSLVTPSTHTVITPTHAQMAT 1472

Query: 188  VSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKD------NSFSGQNTAISHPSPLP 241
              +A+  S    ++P   T     ++  AP + P         +SFS   T    P+ L 
Sbjct: 1473 --SASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKT----PTSLH 1526

Query: 242  PLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSLSCPV 301
               S  HH + + +  +T+T   P   ST+      HT S   +   P          P 
Sbjct: 1527 SHTSSTHHPEVTPTSTTTIT---PNPTSTRTRTPVAHTNSATSSRPPP----------PF 1573

Query: 302  MQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHP 336
              +  P  SSP  ST    ++   +T T PT +HP
Sbjct: 1574 TTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHP 1608



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 95/459 (20%), Positives = 162/459 (35%), Gaps = 90/459 (19%)

Query: 4    PAGSSHPAASARIPPKFG------GAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGY 57
            P   +  A S+R+P  F       G     +  P    +         P+     +P+  
Sbjct: 1781 PVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHV 1840

Query: 58   GLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLY 117
                 + + PS H          +P  TQ     S ++++PT  + P T  +  G+    
Sbjct: 1841 PSFSTSLVTPSTH-------TVIIPTHTQMATSAS-IHSMPTGTIPPPTTIKATGSTHT- 1891

Query: 118  SRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFP 177
                 AP +  +T G+ Q + SS S   TS S PY +   H+  P +   S++  +    
Sbjct: 1892 -----APPMTPTTSGTSQ-SPSSFSTAKTSTSLPYHTSSTHH--PEVTPTSTTNITPKHT 1943

Query: 178  STCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHP 237
            ST     ++  ++A+   +  P           FT+ + PT       S +G  TA S  
Sbjct: 1944 STGTRTPVAHTTSASSSRLPTP-----------FTTHSPPTGS--SPFSSTGPMTATSFQ 1990

Query: 238  SPLP-PLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHT--GSLAVANNNPTITVA 294
            +    P PS   H Q +L  +     +S   PST   +I  HT   + A  ++ PT TV 
Sbjct: 1991 TTTTYPTPS---HPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVP 2047

Query: 295  DSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHPVEPVTSVTQPSELLQQKG 354
               +     +     ++P ++   SG+S + S+ +  TA+      +S    S  L Q  
Sbjct: 2048 PPTTLKATGSTH---TAPPMTVTTSGTSQTHSSFSTATAS------SSFISSSSWLPQ-- 2096

Query: 355  VQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVDSSSTTSSASPMPNSYDALEGGSY 414
                                                 +SS+   +SP+      L   + 
Sbjct: 2097 -------------------------------------NSSSRPPSSPITTQLPHLSSATT 2119

Query: 415  PDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQPS 453
            P   ++  SS        P   S+  P+S  +P    PS
Sbjct: 2120 PVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPS 2158



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 76/384 (19%), Positives = 143/384 (37%), Gaps = 44/384 (11%)

Query: 95   YTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSS 154
            ++ PT  + P T  +  G+         AP I  +T G+ Q  +S +++   ++   ++S
Sbjct: 1477 HSAPTGTIPPPTTLKATGSTHT------APPITPTTSGTSQAHSSFSTNKTPTSLHSHTS 1530

Query: 155  FVNHYNSPAMYSASSSVASQGFPSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQ 214
              +H   P +   S++  +   P+       + V++    + S P  P        FT+ 
Sbjct: 1531 STHH---PEVTPTSTTTIT---PNPTSTRTRTPVAHTNSATSSRPPPP--------FTTH 1576

Query: 215  NAPTVRPVKDNSFSGQNTAISHPSPLP-PLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDN 273
            + PT       S +G  TA S  +    P PS   H Q +L  +     +S   PST   
Sbjct: 1577 SPPTGS--SPFSSTGPMTATSFKTTTTYPTPS---HPQTTLPTHVPPFSTSLVTPSTHTV 1631

Query: 274  LIRNHT--GSLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPP 331
            +   H    + A  ++ PT T+    +     +     ++P ++   SG+S + S+    
Sbjct: 1632 ITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTH---TAPTMTLTTSGTSQALSSLNTA 1688

Query: 332  TANHPVEPVTSVTQPSELLQQKGVQYGEYVNNQASSAPTPLSSTSDDEEEEEEDEEAGVD 391
              +  +   TS T  +E              N  S+   P++ T+    +          
Sbjct: 1689 KTSTSLHSHTSSTHHAEATSTSTTNI---TPNPTSTGTPPMTVTTSGTSQ---------- 1735

Query: 392  SSSTTSSASPMPNSYDALEGGSYPDMLSSSASSPAPDPAPEPDPASAPAPASAPAPVVPQ 451
            S S+ S+A    + +       +P++ S+S +S  P+              SA +  +P 
Sbjct: 1736 SRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795

Query: 452  PSKMAKPFGYGYPTLQPGYQNATA 475
            P     P     P    G   AT+
Sbjct: 1796 PFTTHSPPTGTTPISSTGPVTATS 1819



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 69/339 (20%), Positives = 130/339 (38%), Gaps = 69/339 (20%)

Query: 4    PAGSSHPAASARIPPKFG------GAAVSGAAAPAGPGAGPAPHQQNGPAQNQMQVPSGY 57
            P   ++ A S+R PP F       G++   +  P    +         P+  Q  +P+  
Sbjct: 1557 PVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHV 1616

Query: 58   GLHHQNYIAPSGHYSQGPGKMTSLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLY 117
                 + + PS H    P   T   + T      ++++++PT  + P T  +  G+    
Sbjct: 1617 PPFSTSLVTPSTHTVITP---THAQMATS-----ASIHSMPTGTIPPPTTLKATGSTHT- 1667

Query: 118  SRGPPAPHIVGSTLGSFQGAASSASHLHTSASQPYSSFVNHYNSPAMYSASSSVASQGFP 177
                 AP +  +T G+ Q  +S  +   +++   ++S  +H    A  +++S+      P
Sbjct: 1668 -----APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHH----AEATSTSTTNITPNP 1718

Query: 178  STCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDNSFSGQNTAISHP 237
            ++ G   M+  ++                     TSQ+         +SFS   T+ S  
Sbjct: 1719 TSTGTPPMTVTTSG--------------------TSQSR--------SSFSTAKTSTS-- 1748

Query: 238  SPLPPLPSQQHHQQQSLSGYSTLTWSSPGLPSTQDNLIRNHTGSLAVANNNPTITVADSL 297
              L    S  HH + + +  +++T   P   ST       HT S A ++  PT       
Sbjct: 1749 --LHSHTSSTHHPEVTSTSTTSIT---PNHTSTGTRTPVAHTTS-ATSSRLPT------- 1795

Query: 298  SCPVMQNVQPPKSSPVVSTVLSGSSGSSSTRTPPTANHP 336
              P   +  P  ++P+ ST    ++   +T T PT +HP
Sbjct: 1796 --PFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHP 1832



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 64/278 (23%), Positives = 99/278 (35%), Gaps = 70/278 (25%)

Query: 80   SLPLDTQCGDYYSALYTVPTQNVTPNTVNQQPGAQQLYSRGPPAPHIVGST----LGSFQ 135
            S P+ TQ     SA   V T N   ++ +  P A    S   P+ H    T    +G+  
Sbjct: 2104 SSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSS 2163

Query: 136  GAASSASHLHTSASQPYSSFVNHYNS---------PAMYSASSSVA-------SQGF--- 176
               S+  H  T +S  +SS   H  +         P+  +AS+++        S  F   
Sbjct: 2164 SFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLS 2223

Query: 177  -----------PSTCGHYAMSTVSNAAYPSVSYPSLPAGDTYGQMFTSQNAPTVRPVKDN 225
                       P+   H A ST        +++PS P         ++  AP        
Sbjct: 2224 ALLPISTVTVSPTPSSHLASST--------IAFPSTPRTTA-----STHTAP-------- 2262

Query: 226  SFSGQNTAISHPSPLPPLPSQQHHQQQSLSGYSTLTWSSPGLP-STQDNLIRNHTG---- 280
            +FS Q+T     S    +P+         SG+ +LT    G+P S   NL   H G    
Sbjct: 2263 AFSSQSTTSRSTSLTTRVPT---------SGFVSLTSGVTGIPTSPVTNLTTRHPGPTLS 2313

Query: 281  -SLAVANNNPTITVADSLSCPVMQNVQPPKSSPVVSTV 317
             +     ++ T   +   S PV     P  +SP V +V
Sbjct: 2314 PTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSV 2351


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,231,289
Number of Sequences: 37866
Number of extensions: 2974928
Number of successful extensions: 39721
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 270
Number of HSP's successfully gapped in prelim test: 1215
Number of HSP's that attempted gapping in prelim test: 24421
Number of HSP's gapped (non-prelim): 9946
length of query: 1268
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1154
effective length of database: 13,930,794
effective search space: 16076136276
effective search space used: 16076136276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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