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Search of human proteins with 112293287
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112293287 tudor domain containing 7 [Homo sapiens]
(1098 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112293287 tudor domain containing 7 [Homo sapiens] 2224 0.0
gi|38505161 tudor domain containing 1 [Homo sapiens] 109 2e-23
gi|40255178 tudor domain containing 5 [Homo sapiens] 92 4e-18
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 82 4e-15
gi|145312246 tudor and KH domain containing isoform b [Homo sapi... 82 4e-15
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 82 4e-15
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 82 4e-15
gi|58197558 tudor domain containing 6 [Homo sapiens] 74 6e-13
gi|94421471 ring finger protein 17 [Homo sapiens] 64 8e-10
gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens] 61 5e-09
gi|169163653 PREDICTED: similar to tudor domain containing 1 [Ho... 59 2e-08
gi|169164192 PREDICTED: similar to tudor domain containing 1 [Ho... 59 2e-08
gi|169163210 PREDICTED: similar to tudor domain containing 1 [Ho... 59 2e-08
gi|77404397 staphylococcal nuclease domain containing 1 [Homo sa... 46 2e-04
gi|166851804 tudor domain containing 9 [Homo sapiens] 37 0.10
gi|49472835 bridging integrator 2 [Homo sapiens] 36 0.23
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca... 33 1.1
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca... 33 1.1
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca... 33 1.1
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal... 33 1.1
gi|9961250 ATP-binding cassette, subfamily B, member 4 isoform B... 33 1.1
gi|9961252 ATP-binding cassette, subfamily B, member 4 isoform C... 33 1.1
gi|4505771 ATP-binding cassette, subfamily B, member 4 isoform A... 33 1.1
gi|188497683 FAST kinase domains 1 [Homo sapiens] 33 1.1
gi|110349786 Alstrom syndrome 1 [Homo sapiens] 33 1.5
gi|66571327 ring finger protein 213 [Homo sapiens] 33 1.5
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 33 1.9
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 33 1.9
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 33 1.9
gi|62899047 RAD50 interactor 1 [Homo sapiens] 33 1.9
>gi|112293287 tudor domain containing 7 [Homo sapiens]
Length = 1098
Score = 2224 bits (5764), Expect = 0.0
Identities = 1098/1098 (100%), Positives = 1098/1098 (100%)
Query: 1 MLEGDLVSKMLRAVLQSHKNGVALPRLQGEYRSLTGDWIPFKQLGFPTLEAYLRSVPAVV 60
MLEGDLVSKMLRAVLQSHKNGVALPRLQGEYRSLTGDWIPFKQLGFPTLEAYLRSVPAVV
Sbjct: 1 MLEGDLVSKMLRAVLQSHKNGVALPRLQGEYRSLTGDWIPFKQLGFPTLEAYLRSVPAVV 60
Query: 61 RIETSRSGEITCYAMACTETARIAQLVARQRSSKRKTGRQVNCQMRVKKTMPFFLEGKPK 120
RIETSRSGEITCYAMACTETARIAQLVARQRSSKRKTGRQVNCQMRVKKTMPFFLEGKPK
Sbjct: 61 RIETSRSGEITCYAMACTETARIAQLVARQRSSKRKTGRQVNCQMRVKKTMPFFLEGKPK 120
Query: 121 ATLRQPGFASNFSVGKKPNPAPLRDKGNSVGVKPDAEMSPYMLHTTLGNEAFKDIPVQRH 180
ATLRQPGFASNFSVGKKPNPAPLRDKGNSVGVKPDAEMSPYMLHTTLGNEAFKDIPVQRH
Sbjct: 121 ATLRQPGFASNFSVGKKPNPAPLRDKGNSVGVKPDAEMSPYMLHTTLGNEAFKDIPVQRH 180
Query: 181 VTMSTNNRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNVKPPASYTYKMDEVQNR 240
VTMSTNNRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNVKPPASYTYKMDEVQNR
Sbjct: 181 VTMSTNNRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNVKPPASYTYKMDEVQNR 240
Query: 241 IKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHICTVEKPCSGGQDLLLYP 300
IKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHICTVEKPCSGGQDLLLYP
Sbjct: 241 IKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHICTVEKPCSGGQDLLLYP 300
Query: 301 AKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEKVADLLVKYTSGLWASA 360
AKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEKVADLLVKYTSGLWASA
Sbjct: 301 AKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEKVADLLVKYTSGLWASA 360
Query: 361 LPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYAKLPLPTDKIQKDAGQA 420
LPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYAKLPLPTDKIQKDAGQA
Sbjct: 361 LPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYAKLPLPTDKIQKDAGQA 420
Query: 421 HGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSVLVVELSNTNEVVI 480
HGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSVLVVELSNTNEVVI
Sbjct: 421 HGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSVLVVELSNTNEVVI 480
Query: 481 RYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEEN 540
RYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEEN
Sbjct: 481 RYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEEN 540
Query: 541 KIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTC 600
KIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTC
Sbjct: 541 KIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLSDDPDLVKVVESLTC 600
Query: 601 GKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTN 660
GKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTN
Sbjct: 601 GKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTN 660
Query: 661 ICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLR 720
ICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLR
Sbjct: 661 ICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLR 720
Query: 721 VEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSI 780
VEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSI
Sbjct: 721 VEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSI 780
Query: 781 GMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNAD 840
GMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNAD
Sbjct: 781 GMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNAD 840
Query: 841 LWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEE 900
LWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEE
Sbjct: 841 LWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEE 900
Query: 901 LPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVE 960
LPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVE
Sbjct: 901 LPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVE 960
Query: 961 KDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAV 1020
KDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAV
Sbjct: 961 KDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAV 1020
Query: 1021 TAQLAGVKCNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTD 1080
TAQLAGVKCNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTD
Sbjct: 1021 TAQLAGVKCNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTD 1080
Query: 1081 TWIHDFMSEYLIELSKVN 1098
TWIHDFMSEYLIELSKVN
Sbjct: 1081 TWIHDFMSEYLIELSKVN 1098
>gi|38505161 tudor domain containing 1 [Homo sapiens]
Length = 1189
Score = 109 bits (272), Expect = 2e-23
Identities = 159/620 (25%), Positives = 246/620 (39%), Gaps = 107/620 (17%)
Query: 526 EDAWLRA--QVISTEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGL- 582
+ W RA Q + ++ K V Y+DYG E + ++ Y LN A KC +A +
Sbjct: 326 DQTWNRAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLNRNIDLFPPCAIKCFVANVI 385
Query: 583 ---------------EVLSDDPDLVKVVESLTCGKI-FAVEI--------LDKADIPLVV 618
+L + +K+V+ L + FAVE+ LD I +
Sbjct: 386 PAEGNWSSDCIKATKPLLMEQYCSIKIVDILEEEVVTFAVEVELPNSGKLLDHVLIEMGY 445
Query: 619 LYDTSGEDDININA------------TCLKAICDKS----LEVHLQVDAMYTNVKVTNIC 662
SG+D NA T + DKS + L V + V V +I
Sbjct: 446 GLKPSGQDSKKENADQSDPEDVGKMTTENNIVVDKSDLIPKVLTLNVGDEFCGV-VAHIQ 504
Query: 663 SDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICL--FHCKGKWLR 720
+ +CQ G KL++L + Y S+ + P G IC F +W R
Sbjct: 505 TPEDFFCQQLQSG-RKLAELQASLSKYCDQLPPRSDFY---PAIGDICCAQFSEDDQWYR 560
Query: 721 VEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSI 780
+ S ++ V ++D G + + L I P+ L+ +P QAIKC LA + S+
Sbjct: 561 ASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLE----LPMQAIKCVLAGVKPSL 616
Query: 781 GMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNAD 840
G+WTP+A+ ++ V N I V VD+ + V L PH S+++ + +A
Sbjct: 617 GIWTPEAICLMKKLVQNKI---ITVKVVDKLENSSLVELIDKSE--TPHVSVSKVLLDAG 671
Query: 841 LWKHQKDVFLSAISSGADSPNS-KNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTE 899
++ + D P+ K ++P+ G G+ T V + VD T
Sbjct: 672 FAVGEQSMV-------TDKPSDVKETSVPL-GVEGKVNPLEWTWV--ELGVDQT------ 715
Query: 900 ELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQE--IHKLEVLMEEMILYYSVSEERHI 957
+DV V V PG F +E + KL L + + +
Sbjct: 716 --------------VDVVVCVIYSPGEFYCHVLKEDALKKLNDLNKSLAEHCQQKLPNGF 761
Query: 958 AVEKDQVYAAKV--ENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKL 1015
E Q A + W+R L+K IL NG V V+ +DYG E V +++ + F L
Sbjct: 762 KAEIGQPCCAFFAGDGSWYRALVKEILPNGHVKVHFVDYGNIEEVTADELRMISSTFLNL 821
Query: 1016 PFQAVTAQLAGVKC--NQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVD 1073
PFQ + QLA ++ WSEEA F+ V L A V V EN +
Sbjct: 822 PFQGIRCQLADIQSRNKHWSEEAITRFQMCVAGIKLQARVVEVTENG-----------IG 870
Query: 1074 TSLPDTDTWIHDFMSEYLIE 1093
L D T +S+ LI+
Sbjct: 871 VELTDLSTCYPRIISDVLID 890
Score = 105 bits (263), Expect = 2e-22
Identities = 142/584 (24%), Positives = 237/584 (40%), Gaps = 86/584 (14%)
Query: 524 AEEDAWLRAQVIS-TEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGL 582
+E+D W RA V++ E + V YVDYG E + + + PK L QA KC LAG+
Sbjct: 553 SEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLELPMQAIKCVLAGV 612
Query: 583 EVLSD--DPDLVKVVESLTCGKIFAVEILDKAD-IPLVVLYDTSGEDDININATCLKA-- 637
+ P+ + +++ L KI V+++DK + LV L D S ++++ L A
Sbjct: 613 KPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSSLVELIDKSETPHVSVSKVLLDAGF 672
Query: 638 -------ICDKSLE---------------------VHLQVDAMYTNVKVTNICSDGTLYC 669
+ DK + V L VD +V V I S G YC
Sbjct: 673 AVGEQSMVTDKPSDVKETSVPLGVEGKVNPLEWTWVELGVD-QTVDVVVCVIYSPGEFYC 731
Query: 670 QVPCK-GLNKLSDLLRKIEDYFHCKHMTSECF---VSLPFCGKICLFHCKGKWLRVEITN 725
V + L KL+DL + + + HC+ F + P C F G W R +
Sbjct: 732 HVLKEDALKKLNDLNKSLAE--HCQQKLPNGFKAEIGQPCC---AFFAGDGSWYRALVKE 786
Query: 726 VHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTP 785
+ + + V F+D G + V ELR I FL +P Q I+C LAD+ W+
Sbjct: 787 ILPNGHVKVHFVDYGNIEEVTADELRMISSTFLN----LPFQGIRCQLADIQSRNKHWSE 842
Query: 786 DAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQ 845
+A+ + V +V +V E GI D R I++ + +H
Sbjct: 843 EAITRFQMCVAGIK-LQARVVEVTE-NGIG-------VELTDLSTCYPRIISDVLIDEH- 892
Query: 846 KDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPV 905
+ L + S D PN + N K+ V + + +SA + + PV
Sbjct: 893 --LVLKSASPHKDLPNDRLVN------------KHELQVHVQGLQATSSAEQWKTIELPV 938
Query: 906 HLSKPGEHMDVYVPVACHPGYFVIQPW---QEIHKLEVLMEEMILYYSVSEER-HIAVEK 961
+ +++ P F P + KL +L E++ Y + + R
Sbjct: 939 DKTIQANVLEI-----ISPNLFYALPKGMPENQEKLCMLTAELLEYCNAPKSRPPYRPRI 993
Query: 962 DQVYAAKV--ENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQA 1019
AK ++ W+R ++ G ++ V V DYG E + + +VQP+ LPFQ
Sbjct: 994 GDACCAKYTSDDFWYRAVVLG-TSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQI 1052
Query: 1020 VTAQLAGVK--CNQWSEEASMVFRNHVEKKPLVALVQTVIENAN 1061
+ L G+ S+ M+ +N + + ++ V+ + +N +
Sbjct: 1053 IRCSLEGLMELNGSSSQLIIMLLKNFMLNQNVMLSVKGITKNVH 1096
Score = 68.9 bits (167), Expect = 2e-11
Identities = 103/482 (21%), Positives = 191/482 (39%), Gaps = 64/482 (13%)
Query: 606 VEILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTNICSDG 665
VE+ +K+D PL V +I I A + +SL++ ++ T VT G
Sbjct: 227 VEVNNKSDCPLGVT------KEIAIWAERIMFSDLRSLQLKKTMEIKGT---VTEFKHPG 277
Query: 666 TLYCQV----PCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICL--FHCKGKWL 719
Y Q+ + +N+LS L++ H K +P G++C+ + W
Sbjct: 278 DFYVQLYSSEVLEYMNQLSASLKETYANVHEKDY-------IPVKGEVCIAKYTVDQTWN 330
Query: 720 RVEITNVH-SSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQ 778
R I NV + V ++D G + ++ + + + + PP AIKC +A++
Sbjct: 331 RAIIQNVDVQQKKAHVLYIDYGNEEIIPLNRIYHLN----RNIDLFPPCAIKCFVANVIP 386
Query: 779 SIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITN 838
+ G W+ D + + ++ CSIK+ + E + P+ + ++ +
Sbjct: 387 AEGNWSSDCIKATKPLLME-QYCSIKIVDILEEEVVTFA---VEVELPNSGKLLDHVLI- 441
Query: 839 ADLWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFST 898
++ SG DS EN ++ + + K ++
Sbjct: 442 --------EMGYGLKPSGQDSKK-------------ENADQSDPEDVGKMTTENNIVVDK 480
Query: 899 EELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEER--- 955
+L P V G+ V P F Q Q KL L + Y R
Sbjct: 481 SDLIPKVLTLNVGDEFCGVVAHIQTPEDFFCQQLQSGRKLAELQASLSKYCDQLPPRSDF 540
Query: 956 HIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKL 1015
+ A+ +++W+R + + V V +DYG E++++ ++ P++ +L
Sbjct: 541 YPAIGDICCAQFSEDDQWYRASVLAYASEESVLVGYVDYGNFEILSLMRLCPIIPKLLEL 600
Query: 1016 PFQAVTAQLAGVK--CNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVD 1073
P QA+ LAGVK W+ EA + + V+ K + V +EN++ +V L+D
Sbjct: 601 PMQAIKCVLAGVKPSLGIWTPEAICLMKKLVQNKIITVKVVDKLENSS------LVELID 654
Query: 1074 TS 1075
S
Sbjct: 655 KS 656
Score = 48.1 bits (113), Expect = 4e-05
Identities = 41/170 (24%), Positives = 73/170 (42%), Gaps = 10/170 (5%)
Query: 421 HGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSVLVVELSNTNEVVI 480
H D +V + LQV ++ ++ + T+ +P + + V+E+ + N +
Sbjct: 901 HKDLPNDRLVNKHELQVHVQGLQATSSAEQWKTIE---LPVDKTIQANVLEIISPN--LF 955
Query: 481 RYVGKDYSAAQE---LMEDEMKEYYSKNPKITPVQAVNVGQLLAVN-AEEDAWLRAQVIS 536
+ K QE ++ E+ EY + PK P +G +D W RA V+
Sbjct: 956 YALPKGMPENQEKLCMLTAELLEYCNA-PKSRPPYRPRIGDACCAKYTSDDFWYRAVVLG 1014
Query: 537 TEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLS 586
T + ++V Y DYG E + + + +L FQ +C L GL L+
Sbjct: 1015 TSDTDVEVLYADYGNIETLPLCRVQPITSSHLALPFQIIRCSLEGLMELN 1064
>gi|40255178 tudor domain containing 5 [Homo sapiens]
Length = 981
Score = 91.7 bits (226), Expect = 4e-18
Identities = 163/709 (22%), Positives = 277/709 (39%), Gaps = 157/709 (22%)
Query: 5 DLVSKMLRAVLQSHKNGVALPRLQGEYRSLTGDWIPFKQLGFPTLEAYLRSVPAVVRIET 64
+ + K +R++L S K+G++ L+ EY + G+ +P + LG+ + + +P VVR+
Sbjct: 9 ECLRKEIRSLLISTKDGLSPQELEKEYLLMVGNHLPLRILGYRSTMELVLDMPDVVRVCP 68
Query: 65 SRSGEITCYAMACTETARIAQLVARQRSSKR----------------KTGRQVNCQMRVK 108
G + A+ T IA LVA+QRSS + ++ R+V + RV
Sbjct: 69 GAGGTVILKAIPDESTKGIASLVAKQRSSHKLRNSMHKGRPSIYSGPRSHRRVPYRGRVA 128
Query: 109 KTMPFFLEGKPKATLR------------------------QPGFASNFSVGKKPNPAPLR 144
+P ++ + K L Q GF S F V L
Sbjct: 129 PILPAVVKSELKDLLALSPVLLSDFEKAFAKRFGRSFQYMQYGFLSMFEV--------LN 180
Query: 145 DKGNSVGVKPDAEMSPYMLHTTLGNEAFKDIPVQRHVTMSTNNR--------------FS 190
+ + V+ S ML ++ E + P + T + FS
Sbjct: 181 AASDVISVEQTRAGSLLMLKKSVTEEKPRGCPAGKIFTQPFRMKQGSYSTGFPVAKPCFS 240
Query: 191 -PKASLQPPLQ-MHLSRTSTKEM--SDNLNQTVEKPNVKPPASYTYKM------------ 234
P ++++PP Q M + +TS + + LN T EK N T+K
Sbjct: 241 QPTSNMEPPKQIMSMEKTSKLNVVETSRLNHT-EKLN---QLENTFKSVIAQIGPGGTIS 296
Query: 235 DEVQNRIKEILNKHNNGIWISKLPHFYKELYKEDLNQ---GILQQFE---HWPHICTVEK 288
E++++IK +++K G++ISKL Y+ ++KE L+ G L E I VE
Sbjct: 297 SELKHKIKFVVSKFPEGLFISKLLGEYEVIFKEQLSPKKLGFLNVTELVGALSDILHVEF 356
Query: 289 PCSGGQDLLLYPAKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEKVADL 348
G QDLL++ D +K PL P+ K+ K C ++ + ++
Sbjct: 357 R-KGHQDLLVF------------DADKKPLPPVQSDKKIEA-KAC---VSSPPRNSLSTA 399
Query: 349 LVKYTSGLWASALPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYAKLPL 408
VK T +W K E K+ C P + +L +
Sbjct: 400 AVKET--VWNCPSKKQKEPQQKI----------------CK------KPNLVVKPLQLQV 435
Query: 409 PTDKIQKDAGQAHGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSVL 468
T+K + + A+ D A+ ++ ++ PPL T + V
Sbjct: 436 ETNKSELNLAMANHDIPPDAVPNKKLCRL-----------------PPL--DTSSLIGVF 476
Query: 469 VVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSK----NPKITPVQAVNVGQLLAVNA 524
V + + ++ IR +D S E M EM+ YS + + P + G L V
Sbjct: 477 VEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCVRI 536
Query: 525 EEDAWLRAQVIST--EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGL 582
ED W +I E+ +++V Y D+G V+KS L + L QA C LA +
Sbjct: 537 SEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLAWV 596
Query: 583 EVLSDDPDLVKVVE-SLTCGKIFAVEILDK--ADIPLVVLYDTSGEDDI 628
+ + +++ CG V ++D+ I + L DTS +D+
Sbjct: 597 RPVEEHWTSKAILQFQKLCGLKPLVGVVDEYVDGILNIFLCDTSSNEDV 645
Score = 48.5 bits (114), Expect = 3e-05
Identities = 48/181 (26%), Positives = 85/181 (46%), Gaps = 19/181 (10%)
Query: 916 VYVPVACHPGYFVIQPWQEIHK--LEVLMEEMILYYS--VSEERHIA----VEKDQVYAA 967
V+V P F I+ + LE +M EM YS + +R++ ++ +
Sbjct: 475 VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYVMPECFIQPGHLCCV 534
Query: 968 KV-ENKW-HRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLA 1025
++ E+KW +RV++ +L V V+ D+G +V ++ L + KLP QA+ LA
Sbjct: 535 RISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSLRFLKCCYTKLPAQAIPCSLA 594
Query: 1026 GVKC--NQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTSLPDTDTWI 1083
V+ W+ +A + F+ KPLV +V + D + ++L DTS + D +
Sbjct: 595 WVRPVEEHWTSKAILQFQKLCGLKPLVGVVDEYV------DGILNIFLCDTS-SNEDVYF 647
Query: 1084 H 1084
H
Sbjct: 648 H 648
Score = 36.6 bits (83), Expect = 0.13
Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 18/132 (13%)
Query: 693 KHMTSECFVSLPFCGKICLFHCKGK--WLRVEITNVHSSRALDVQFLDSGTVTSVKVSEL 750
+++ ECF+ G +C W RV I V + ++V + D G + V+ S L
Sbjct: 518 RYVMPECFIQP---GHLCCVRISEDKWWYRVIIHRVLEKQEVEVFYPDFGNIGIVQKSSL 574
Query: 751 REIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCSDCSIK--VTKV 808
R + + + +P QAI C LA + WT A+L + C +K V V
Sbjct: 575 RFLKCCYTK----LPAQAIPCSLAWVRPVEEHWTSKAILQFQKL------CGLKPLVGVV 624
Query: 809 DE-TRGIAHVYL 819
DE GI +++L
Sbjct: 625 DEYVDGILNIFL 636
>gi|145312259 tudor and KH domain containing isoform a [Homo sapiens]
Length = 561
Score = 81.6 bits (200), Expect = 4e-15
Identities = 63/225 (28%), Positives = 105/225 (46%), Gaps = 12/225 (5%)
Query: 860 PNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVP 919
P G+M + + ++ K D +KS E+P P E+++VYV
Sbjct: 254 PPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVS 313
Query: 920 VACHPGYFVIQ-PWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRV 976
+ HP +F IQ +L+ L+ EM +Y S + V + AA + W+R
Sbjct: 314 ASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRA 373
Query: 977 LLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--KCNQWSE 1034
+ G L NG + +Y +D+G + ++ ++ L F LPFQA+ LA + +QW E
Sbjct: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
Query: 1035 EASMVF---RNHVEKKPLVALVQTVIENA-NPWDRKVVVYLVDTS 1075
EA F + + KPLVA + + ++ + W + +YL DTS
Sbjct: 434 EALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK---IYLYDTS 475
Score = 47.8 bits (112), Expect = 6e-05
Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 30/261 (11%)
Query: 449 MEDITVPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKI 508
M +I P + V V + N I+ VG +L+ + + Y + P+
Sbjct: 292 MFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPED 351
Query: 509 TPVQAVNVGQLLAVNAEED-AWLRAQVISTEEN-KIKVCYVDYGFSENVEKSKAYKLNPK 566
V+VG ++A + +W RA+V+ T EN + + +VD+G + + L
Sbjct: 352 L---TVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD 408
Query: 567 FCSLSFQATKCKLAGLEVLSD--DPDLVKVVESLT--------CGKIFAVEILDKADIPL 616
F SL FQA +C LA + D + + + + LT KI + + P
Sbjct: 409 FLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK 468
Query: 617 VVLYDTSGEDDININATCL---------------KAICDKSLEVHLQVDAMYTNVKVTNI 661
+ LYDTS ++I + +A+ D ++ + DA + +
Sbjct: 469 IYLYDTSNGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETK 528
Query: 662 CSDGTLYCQVPCKGLNKLSDL 682
S G + + C L++ + +
Sbjct: 529 KSSGEITHTLSCLSLSEAASM 549
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 716 GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLAD 775
G W R + + LD+ F+D G + +LR + FL ++P QAI+C LA
Sbjct: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL----SLPFQAIECSLAR 423
Query: 776 LPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDE--TRGIA---HVYLFTPKN 824
+ S W +A L D + +C+D V K+ GI+ +YL+ N
Sbjct: 424 IAPSGDQWEEEA-LDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSN 476
>gi|145312246 tudor and KH domain containing isoform b [Homo sapiens]
Length = 516
Score = 81.6 bits (200), Expect = 4e-15
Identities = 63/225 (28%), Positives = 105/225 (46%), Gaps = 12/225 (5%)
Query: 860 PNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVP 919
P G+M + + ++ K D +KS E+P P E+++VYV
Sbjct: 209 PPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVS 268
Query: 920 VACHPGYFVIQ-PWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRV 976
+ HP +F IQ +L+ L+ EM +Y S + V + AA + W+R
Sbjct: 269 ASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRA 328
Query: 977 LLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--KCNQWSE 1034
+ G L NG + +Y +D+G + ++ ++ L F LPFQA+ LA + +QW E
Sbjct: 329 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 388
Query: 1035 EASMVF---RNHVEKKPLVALVQTVIENA-NPWDRKVVVYLVDTS 1075
EA F + + KPLVA + + ++ + W + +YL DTS
Sbjct: 389 EALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK---IYLYDTS 430
Score = 47.8 bits (112), Expect = 6e-05
Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 30/261 (11%)
Query: 449 MEDITVPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKI 508
M +I P + V V + N I+ VG +L+ + + Y + P+
Sbjct: 247 MFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPED 306
Query: 509 TPVQAVNVGQLLAVNAEED-AWLRAQVISTEEN-KIKVCYVDYGFSENVEKSKAYKLNPK 566
V+VG ++A + +W RA+V+ T EN + + +VD+G + + L
Sbjct: 307 L---TVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD 363
Query: 567 FCSLSFQATKCKLAGLEVLSD--DPDLVKVVESLT--------CGKIFAVEILDKADIPL 616
F SL FQA +C LA + D + + + + LT KI + + P
Sbjct: 364 FLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK 423
Query: 617 VVLYDTSGEDDININATCL---------------KAICDKSLEVHLQVDAMYTNVKVTNI 661
+ LYDTS ++I + +A+ D ++ + DA + +
Sbjct: 424 IYLYDTSNGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETK 483
Query: 662 CSDGTLYCQVPCKGLNKLSDL 682
S G + + C L++ + +
Sbjct: 484 KSSGEITHTLSCLSLSEAASM 504
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 716 GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLAD 775
G W R + + LD+ F+D G + +LR + FL ++P QAI+C LA
Sbjct: 323 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL----SLPFQAIECSLAR 378
Query: 776 LPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDE--TRGIA---HVYLFTPKN 824
+ S W +A L D + +C+D V K+ GI+ +YL+ N
Sbjct: 379 IAPSGDQWEEEA-LDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSN 431
>gi|145312270 tudor and KH domain containing isoform a [Homo sapiens]
Length = 561
Score = 81.6 bits (200), Expect = 4e-15
Identities = 63/225 (28%), Positives = 105/225 (46%), Gaps = 12/225 (5%)
Query: 860 PNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVP 919
P G+M + + ++ K D +KS E+P P E+++VYV
Sbjct: 254 PPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVS 313
Query: 920 VACHPGYFVIQ-PWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRV 976
+ HP +F IQ +L+ L+ EM +Y S + V + AA + W+R
Sbjct: 314 ASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRA 373
Query: 977 LLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--KCNQWSE 1034
+ G L NG + +Y +D+G + ++ ++ L F LPFQA+ LA + +QW E
Sbjct: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
Query: 1035 EASMVF---RNHVEKKPLVALVQTVIENA-NPWDRKVVVYLVDTS 1075
EA F + + KPLVA + + ++ + W + +YL DTS
Sbjct: 434 EALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK---IYLYDTS 475
Score = 47.8 bits (112), Expect = 6e-05
Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 30/261 (11%)
Query: 449 MEDITVPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKI 508
M +I P + V V + N I+ VG +L+ + + Y + P+
Sbjct: 292 MFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPED 351
Query: 509 TPVQAVNVGQLLAVNAEED-AWLRAQVISTEEN-KIKVCYVDYGFSENVEKSKAYKLNPK 566
V+VG ++A + +W RA+V+ T EN + + +VD+G + + L
Sbjct: 352 L---TVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD 408
Query: 567 FCSLSFQATKCKLAGLEVLSD--DPDLVKVVESLT--------CGKIFAVEILDKADIPL 616
F SL FQA +C LA + D + + + + LT KI + + P
Sbjct: 409 FLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK 468
Query: 617 VVLYDTSGEDDININATCL---------------KAICDKSLEVHLQVDAMYTNVKVTNI 661
+ LYDTS ++I + +A+ D ++ + DA + +
Sbjct: 469 IYLYDTSNGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETK 528
Query: 662 CSDGTLYCQVPCKGLNKLSDL 682
S G + + C L++ + +
Sbjct: 529 KSSGEITHTLSCLSLSEAASM 549
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 716 GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLAD 775
G W R + + LD+ F+D G + +LR + FL ++P QAI+C LA
Sbjct: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL----SLPFQAIECSLAR 423
Query: 776 LPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDE--TRGIA---HVYLFTPKN 824
+ S W +A L D + +C+D V K+ GI+ +YL+ N
Sbjct: 424 IAPSGDQWEEEA-LDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSN 476
>gi|145312256 tudor and KH domain containing isoform a [Homo sapiens]
Length = 561
Score = 81.6 bits (200), Expect = 4e-15
Identities = 63/225 (28%), Positives = 105/225 (46%), Gaps = 12/225 (5%)
Query: 860 PNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVP 919
P G+M + + ++ K D +KS E+P P E+++VYV
Sbjct: 254 PPKGGGDMAVVVSKEGSWEKPSDDSFQKSEAQAIPEMPMFEIPSPDFSFHADEYLEVYVS 313
Query: 920 VACHPGYFVIQ-PWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKV--ENKWHRV 976
+ HP +F IQ +L+ L+ EM +Y S + V + AA + W+R
Sbjct: 314 ASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPEDLTVHVGDIVAAPLPTNGSWYRA 373
Query: 977 LLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--KCNQWSE 1034
+ G L NG + +Y +D+G + ++ ++ L F LPFQA+ LA + +QW E
Sbjct: 374 RVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFLSLPFQAIECSLARIAPSGDQWEE 433
Query: 1035 EASMVF---RNHVEKKPLVALVQTVIENA-NPWDRKVVVYLVDTS 1075
EA F + + KPLVA + + ++ + W + +YL DTS
Sbjct: 434 EALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK---IYLYDTS 475
Score = 47.8 bits (112), Expect = 6e-05
Identities = 56/261 (21%), Positives = 104/261 (39%), Gaps = 30/261 (11%)
Query: 449 MEDITVPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKI 508
M +I P + V V + N I+ VG +L+ + + Y + P+
Sbjct: 292 MFEIPSPDFSFHADEYLEVYVSASEHPNHFWIQIVGSRSLQLDKLVNEMTQHYENSVPED 351
Query: 509 TPVQAVNVGQLLAVNAEED-AWLRAQVISTEEN-KIKVCYVDYGFSENVEKSKAYKLNPK 566
V+VG ++A + +W RA+V+ T EN + + +VD+G + + L
Sbjct: 352 L---TVHVGDIVAAPLPTNGSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSD 408
Query: 567 FCSLSFQATKCKLAGLEVLSD--DPDLVKVVESLT--------CGKIFAVEILDKADIPL 616
F SL FQA +C LA + D + + + + LT KI + + P
Sbjct: 409 FLSLPFQAIECSLARIAPSGDQWEEEALDEFDRLTHCADWKPLVAKISSYVQTGISTWPK 468
Query: 617 VVLYDTSGEDDININATCL---------------KAICDKSLEVHLQVDAMYTNVKVTNI 661
+ LYDTS ++I + +A+ D ++ + DA + +
Sbjct: 469 IYLYDTSNGKKLDIGLELVHKGYAIELPEDIEENRAVPDMLKDMATETDASLSTLLTETK 528
Query: 662 CSDGTLYCQVPCKGLNKLSDL 682
S G + + C L++ + +
Sbjct: 529 KSSGEITHTLSCLSLSEAASM 549
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 10/114 (8%)
Query: 716 GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLAD 775
G W R + + LD+ F+D G + +LR + FL ++P QAI+C LA
Sbjct: 368 GSWYRARVLGTLENGNLDLYFVDFGDNGDCPLKDLRALRSDFL----SLPFQAIECSLAR 423
Query: 776 LPQSIGMWTPDAVLWLRDSVLNCSDCSIKVTKVDE--TRGIA---HVYLFTPKN 824
+ S W +A L D + +C+D V K+ GI+ +YL+ N
Sbjct: 424 IAPSGDQWEEEA-LDEFDRLTHCADWKPLVAKISSYVQTGISTWPKIYLYDTSN 476
>gi|58197558 tudor domain containing 6 [Homo sapiens]
Length = 2096
Score = 74.3 bits (181), Expect = 6e-13
Identities = 128/598 (21%), Positives = 224/598 (37%), Gaps = 93/598 (15%)
Query: 529 WLRAQVIST--EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEVLS 586
W RA ++ T + +V +VDYG E V S L P++ + C L GL
Sbjct: 326 WYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMPVVTYPCALYGLWDGG 385
Query: 587 DDPDLVKV--VESLTCGKIFAVEILDKADIPLVVLYDTSGEDDININATCLKAIC---DK 641
+V +++L GK +I V GED IN+N C D+
Sbjct: 386 RGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGEDGINLNRVFGVQSCCLADR 445
Query: 642 SLE--------------------------------VHLQVDAMYTNVKVTNICSDGTLYC 669
L+ + L+++A Y + +V + + +
Sbjct: 446 VLQSQATEEEEPETSQSQSPAEEVDEEISLPALRSIRLKMNAFY-DAQVEFVKNPSEFWI 504
Query: 670 QVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCKGKWLRVEITNVHSS 729
++ + S L+R++ F+ + V P +C K I
Sbjct: 505 RLRKHNVT-FSKLMRRMCG-FYSSASKLDGVVLKPEPDDLCCVKWKENGYYRAIVTKLDD 562
Query: 730 RALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMWTPDAVL 789
+++DV +D G +V ++R + P+F Q +P A+KC LAD+ W+ +AV
Sbjct: 563 KSVDVFLVDRGNSENVDWYDVRMLLPQFRQ----LPILAVKCTLADIWPLGKTWSQEAVS 618
Query: 790 WLRDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPDPHRSINRQITNADLWKHQKDVF 849
+ + +VL+ + I + + + + + +I++ I A K+Q+
Sbjct: 619 FFKKTVLH-KELVIHILDKQDHQYVIEIL----DESRTGEENISKVIAQAGYAKYQEFET 673
Query: 850 LSAISSGADSPNSKNGNMPMSGN------TGENFRK----NLTDVIKKSMVDHTSAF--S 897
I A SP + + N TGE +K N T + K++ D T S
Sbjct: 674 KENILVNAHSPGHVSNHFTTESNKIPFAKTGEGEQKAKRENKTTSVSKALSDTTVVTNGS 733
Query: 898 TE---------------------ELPPPVHLS---KPGEHMDVYVPVACHPGYFVIQPWQ 933
TE E+ P + G ++V V +PGYF Q +
Sbjct: 734 TELVVQEKVKRASVYFPLMQNCLEIKPGSSSKGELEVGSTVEVRVSYVENPGYFWCQLTR 793
Query: 934 EIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELD 993
I L+ LM ++ Y + H + V +W R L+ GI + V+V +D
Sbjct: 794 NIQGLKTLMSDIQYYCKNTAAPHQRNTLACLAKRTVNRQWSRALISGIQSVEHVNVTFVD 853
Query: 994 YGKHELVNIRKVQPLVDMFRKLPFQAVTAQL------AGVKCNQWSEEASMVFRNHVE 1045
YG E+V+++ + + + F K+ QA L G W +A F ++
Sbjct: 854 YGDREMVSVKNIYSISEEFLKVKAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFID 911
Score = 61.2 bits (147), Expect = 5e-09
Identities = 92/395 (23%), Positives = 163/395 (41%), Gaps = 66/395 (16%)
Query: 470 VELSNTNEVVIRYVG----------KDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQL 519
+E+ +T EV + YV ++ + LM D +YY KN P Q N
Sbjct: 768 LEVGSTVEVRVSYVENPGYFWCQLTRNIQGLKTLMSDI--QYYCKNTA-APHQR-NTLAC 823
Query: 520 LAVNAEEDAWLRAQVISTEE-NKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCK 578
LA W RA + + + V +VDYG E V Y ++ +F + QA +C
Sbjct: 824 LAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSISEEFLKVKAQAFRCS 883
Query: 579 LAGL-EVLSDDPDL--VKVVES--------------LTCGKIFAVEILDKADIPLV-VLY 620
L L + + +P + VK +++ L C IFA+ +++ +V +L
Sbjct: 884 LYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKC-TIFALASINEELFNIVDLLT 942
Query: 621 DTSGEDDININATCLKAI-CDKSLEVHLQVDAMYTN-----------VKVTNICSDGTLY 668
+ + + K LE +Q+ + + + V +T+I T Y
Sbjct: 943 PFQSACHFLVEKRLARPVKLQKPLESSVQLHSYFYSTHDMKIGSEELVYITHIDDPWTFY 1002
Query: 669 CQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFC----GKICLF-HCKGKWLRVEI 723
CQ+ + N L L I S+ ++L G +CL + G W R +
Sbjct: 1003 CQL-ARNANILEQLSCSITQL-------SKVLLNLKTSPLNPGTLCLAKYTDGNWYRGIV 1054
Query: 724 TNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGMW 783
+ V F+D G + V +L IP +++ +P QA++C L+D+P I
Sbjct: 1055 IEKEPKK---VFFVDFGNIYVVTSDDLLPIPSD-AYDVLLLPMQAVRCSLSDIPDHI--- 1107
Query: 784 TPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVY 818
+ V+W ++++L+ S ++ V K + I +Y
Sbjct: 1108 PEEVVVWFQETILDKSLKALVVAKDPDGTLIIELY 1142
Score = 49.3 bits (116), Expect = 2e-05
Identities = 67/292 (22%), Positives = 112/292 (38%), Gaps = 33/292 (11%)
Query: 519 LLAVNAEEDAWLRAQVISTEENKI-KVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKC 577
+ AV E++ W RA + + N + V ++DYG V +K +L+ L C
Sbjct: 1359 ICAVFPEDNLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHC 1418
Query: 578 KLAGLEVLSD--DPDLVKVVESLTCGKIFAVEILDKADIPLVVLYDTSG--EDDININAT 633
L G EV + ++ T E + D V+L D G DD+ I+
Sbjct: 1419 SLQGFEVPDNKNSKKMMHYFSQRTSEAAIRCEFVKFQDRWEVILADEHGIIADDM-ISRY 1477
Query: 634 CLKAICDKSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCK 693
L L + A +V ++I + L P K + + + +YF C+
Sbjct: 1478 ALSEKSQVELSTQVIKSASSKSVNKSDIDTSVFLNWYNPEKKMIRAYATVIDGPEYFWCQ 1537
Query: 694 HMTSE---CF-----------------VSLPFCGKICLFHCK--GKWLRVEITNVHSSRA 731
+E C + P+ G C+ + G + R ITN+
Sbjct: 1538 FADTEKLQCLEVEVQTAGEQVADRRNCIPCPYIGDPCIVRYREDGHYYRALITNICEDYL 1597
Query: 732 LDVQFLDSGTVTS-VKVSELREIPPRFLQEMIAIPPQAIKCCLADLPQSIGM 782
+ V+ +D G + V L IP E++++P QA CCL+ S G+
Sbjct: 1598 VSVRLVDFGNIEDCVDPKALWAIP----SELLSVPMQAFPCCLSGFNISEGL 1645
Score = 48.1 bits (113), Expect = 4e-05
Identities = 52/195 (26%), Positives = 81/195 (41%), Gaps = 9/195 (4%)
Query: 450 EDITVPPLM---IPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNP 506
E+I++P L + A V + N +E IR + ++ + M +YS
Sbjct: 471 EEISLPALRSIRLKMNAFYDAQVEFVKNPSEFWIRL--RKHNVTFSKLMRRMCGFYSSAS 528
Query: 507 KITPVQAV-NVGQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKLNP 565
K+ V L V +E+ + RA V ++ + V VD G SENV+ L P
Sbjct: 529 KLDGVVLKPEPDDLCCVKWKENGYYRAIVTKLDDKSVDVFLVDRGNSENVDWYDVRMLLP 588
Query: 566 KFCSLSFQATKCKLAGLEVLSD--DPDLVKVVESLTCGKIFAVEILDKADIPLVV-LYDT 622
+F L A KC LA + L + V + K + ILDK D V+ + D
Sbjct: 589 QFRQLPILAVKCTLADIWPLGKTWSQEAVSFFKKTVLHKELVIHILDKQDHQYVIEILDE 648
Query: 623 SGEDDININATCLKA 637
S + NI+ +A
Sbjct: 649 SRTGEENISKVIAQA 663
Score = 44.7 bits (104), Expect = 5e-04
Identities = 48/167 (28%), Positives = 74/167 (44%), Gaps = 13/167 (7%)
Query: 915 DVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAV---EKDQVYAAK-VE 970
D V +P F I+ + LM M +YS + + V E D + K E
Sbjct: 490 DAQVEFVKNPSEFWIRLRKHNVTFSKLMRRMCGFYSSASKLDGVVLKPEPDDLCCVKWKE 549
Query: 971 NKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--K 1028
N ++R ++ L + V V+ +D G E V+ V+ L+ FR+LP AV LA +
Sbjct: 550 NGYYRAIVTK-LDDKSVDVFLVDRGNSENVDWYDVRMLLPQFRQLPILAVKCTLADIWPL 608
Query: 1029 CNQWSEEASMVFRNHVEKKPLVALVQTVIENANPWDRKVVVYLVDTS 1075
WS+EA F+ V K L VI + D + V+ ++D S
Sbjct: 609 GKTWSQEAVSFFKKTVLHKEL------VIHILDKQDHQYVIEILDES 649
Score = 40.8 bits (94), Expect = 0.007
Identities = 41/179 (22%), Positives = 78/179 (43%), Gaps = 23/179 (12%)
Query: 634 CLKAICDKSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCK 693
CL+ S + L+V + V+V+ + + G +CQ+ + + L L+ I+ ++CK
Sbjct: 755 CLEIKPGSSSKGELEVGST-VEVRVSYVENPGYFWCQLT-RNIQGLKTLMSDIQ--YYCK 810
Query: 694 HMTSECFVSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREI 753
+ + + C + +W R I+ + S ++V F+D G V V + I
Sbjct: 811 NTAAPHQRNTLAC--LAKRTVNRQWSRALISGIQSVEHVNVTFVDYGDREMVSVKNIYSI 868
Query: 754 PPRFLQEMIAIPPQAIKCCLADLPQSIG----MWTPDAV---------LWLRDSVLNCS 799
FL+ + QA +C L +L Q +G +W A+ W ++ L C+
Sbjct: 869 SEEFLK----VKAQAFRCSLYNLIQPVGQNPFVWDVKAIQAFNEFIDNAWQKNLELKCT 923
Score = 32.3 bits (72), Expect = 2.5
Identities = 18/57 (31%), Positives = 29/57 (50%)
Query: 970 ENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAG 1026
+N W+R ++K N L+SV +DYG +V+ K+ L + LP + L G
Sbjct: 1366 DNLWYRAVIKEQQPNDLLSVQFIDYGNVSVVHTNKIGRLDLVNAILPGLCIHCSLQG 1422
Score = 31.6 bits (70), Expect = 4.3
Identities = 34/131 (25%), Positives = 53/131 (40%), Gaps = 22/131 (16%)
Query: 916 VYVPVACHPGYFVIQ---PWQEIHKLEVLMEEMILYYSVS-------------EERHIAV 959
V + CHP Q QEIH+L E M Y S EER +
Sbjct: 254 VVITQVCHPHRIHCQLRSVSQEIHRLS---ESMAQVYRGSTGTGDENSTSATWEEREESP 310
Query: 960 EKDQVYAAK--VENKWHR-VLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLP 1016
+K A ++ W+R +LL+ V +DYG+ ELV+ ++ L+ + ++P
Sbjct: 311 DKPGSPCASCGLDGHWYRALLLETFRPQRCAQVLHVDYGRKELVSCSSLRYLLPEYFRMP 370
Query: 1017 FQAVTAQLAGV 1027
L G+
Sbjct: 371 VVTYPCALYGL 381
>gi|94421471 ring finger protein 17 [Homo sapiens]
Length = 1623
Score = 63.9 bits (154), Expect = 8e-10
Identities = 102/465 (21%), Positives = 189/465 (40%), Gaps = 73/465 (15%)
Query: 655 NVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHC 714
+V V +I S G Y Q+ +GL+ L LL+ IE+++ + + P + C+
Sbjct: 681 SVTVCHINSPGDFYLQL-IEGLDILF-LLKTIEEFYKSED-GENLEILCPVQDQACVAKF 737
Query: 715 K-GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCL 773
+ G W R ++ + + ++V+++D G + + ++R+I FL P +AIKC L
Sbjct: 738 EDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNA----PEKAIKCKL 793
Query: 774 ADLP--QSIGMWTPDAVLWL----RDSVLNCSDCSIKVTKVDETRGIAHVYLFTPKNFPD 827
A + + W+ +A +D + CS V K+ E + V LF P+
Sbjct: 794 AYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCS-----VIKILEDN-VLLVELFDSLGAPE 847
Query: 828 -PHRSINRQITNADLWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLT---- 882
SIN Q+ L ++ L +N +K++
Sbjct: 848 MTTTSINDQLVKEGLASYEIGYILK-----------------------DNSQKHIEVWDP 884
Query: 883 --DVIKKSMVDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEV 940
+ I + V + + S + LP S + + V++ P +Q + L
Sbjct: 885 SPEEIISNEVHNLNPVSAKSLPNENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNS 944
Query: 941 LMEEMILYYSVSEERHIAVEKDQVYAAKVE--NKWHRVLLKGILTNGLVSVYELDYGKHE 998
L E+MI Y S+ + E D A K++ N+W R + ++T+ LV V D G
Sbjct: 945 LEEKMIAAYENSKWEPVKWENDMHCAVKIQDKNQWRRGQIIRMVTDTLVEVLLYDVGVEL 1004
Query: 999 LVNIRKVQPLVDMFRKLPFQAVTAQLAGVK----CNQWSEEASMVFRNHVEKKPLVALVQ 1054
+VN+ ++ L + + + ++ L ++ ++W+ A + L V
Sbjct: 1005 VVNVDCLRKLEENLKTMGRLSLECSLVDIRPAGGSDKWTATACDCLSLY-----LTGAVA 1059
Query: 1055 TVI------ENANPWDRKVVVYLVDTSLPDTDTWIHDFMSEYLIE 1093
T+I EN W V ++ D D +S+YLI+
Sbjct: 1060 TIILQVDSEENNTTWPLPVKIFCRDEKGERVD------VSKYLIK 1098
Score = 59.7 bits (143), Expect = 1e-08
Identities = 67/269 (24%), Positives = 123/269 (45%), Gaps = 26/269 (9%)
Query: 830 RSINRQITNADLWKHQKDVFLSAISSGADSPNSKNGNMPMSGNTGENFRKNLTDVIKKSM 889
+ +N + + +++ + V + + PN + +MP+S F + L +S+
Sbjct: 600 KMVNNKAVSMKVFREEDGVLIVDLQK--PPPNKISSDMPVSLRDALVFME-LAKFKSQSL 656
Query: 890 VDHTSAFSTEELPPPVHLSKPGEHMDVYVPVACH---PGYFVIQPWQEIHKLEVLMEEMI 946
H +T PP+ P E DV V V CH PG F +Q + + L L++ +
Sbjct: 657 RSHFEKNTTLHYHPPI---LPKEMTDVSVTV-CHINSPGDFYLQLIEGLDIL-FLLKTIE 711
Query: 947 LYYSVSEERHIAV---EKDQVYAAKVENK-WHRVLLKGILTNGLVSVYELDYGKHELVNI 1002
+Y + ++ + +DQ AK E+ W+R + G+ + V V +D+G + I
Sbjct: 712 EFYKSEDGENLEILCPVQDQACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITI 771
Query: 1003 RKVQPLVDMFRKLPFQAVTAQLAGV----KCNQWSEEASMVFRNHVEKKPLVALVQTVIE 1058
+ V+ + D F P +A+ +LA + + QWS+EA F + K + V ++E
Sbjct: 772 KDVRKIKDEFLNAPEKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILE 831
Query: 1059 NANPWDRKVVVYLVDT-SLPD-TDTWIHD 1085
D ++V L D+ P+ T T I+D
Sbjct: 832 -----DNVLLVELFDSLGAPEMTTTSIND 855
Score = 47.8 bits (112), Expect = 6e-05
Identities = 84/391 (21%), Positives = 155/391 (39%), Gaps = 72/391 (18%)
Query: 455 PPLMIPTEASPSVLVVELSNTNEVVIRYV-GKDYSAAQELMEDEMKEYYSKNPKIT-PVQ 512
PP++ SV V +++ + ++ + G D + +E+ K +N +I PVQ
Sbjct: 670 PPILPKEMTDVSVTVCHINSPGDFYLQLIEGLDILFLLKTIEEFYKSEDGENLEILCPVQ 729
Query: 513 AVNVGQLLAVNAEEDAWLRAQVISTE-ENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLS 571
Q E+ W RA+VI +++V YVD+G + + K+ +F +
Sbjct: 730 ----DQACVAKFEDGIWYRAKVIGLPGHQEVEVKYVDFGNTAKITIKDVRKIKDEFLNAP 785
Query: 572 FQATKCKLAGLE-------------------------------VLSDDPDLVKVVESLTC 600
+A KCKLA +E +L D+ LV++ +SL
Sbjct: 786 EKAIKCKLAYIEPYKRTMQWSKEAKEKFEEKAQDKFMTCSVIKILEDNVLLVELFDSLGA 845
Query: 601 GKIFAVEILDKA--------DIPLVV---------LYDTSGEDDININATCLKAICDKSL 643
++ I D+ +I ++ ++D S E+ I+ L + KSL
Sbjct: 846 PEMTTTSINDQLVKEGLASYEIGYILKDNSQKHIEVWDPSPEEIISNEVHNLNPVSAKSL 905
Query: 644 EVHLQVDAMYTN---VKVTNICSDGTLYCQ--VPCKGLNKLSDLLRKIEDYFHCKHMTSE 698
+ ++Y V + N+ S +Y Q + LN L + + I Y + K +
Sbjct: 906 P-NENFQSLYNKELPVHICNVISPEKIYVQWLLTENLLNSLEE--KMIAAYENSKWEPVK 962
Query: 699 CFVSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFL 758
+ KI K +W R +I + + ++V D G V V LR++
Sbjct: 963 WENDMHCAVKI---QDKNQWRRGQIIRMVTDTLVEVLLYDVGVELVVNVDCLRKLE---- 1015
Query: 759 QEMIAIPPQAIKCCLADLPQSIG--MWTPDA 787
+ + + +++C L D+ + G WT A
Sbjct: 1016 ENLKTMGRLSLECSLVDIRPAGGSDKWTATA 1046
Score = 39.3 bits (90), Expect = 0.021
Identities = 23/101 (22%), Positives = 47/101 (46%), Gaps = 13/101 (12%)
Query: 517 GQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKL-----NPKFCSLS 571
G+ AV + W R +V+ ++V Y+D+GF+E + + Y + P+FC
Sbjct: 1232 GEACAVRGSDTLWYRGKVMEVVGGAVRVQYLDHGFTEKIPQCHLYPILLYPDIPQFC--- 1288
Query: 572 FQATKCKLAGLEVLSD--DPDLVKVVESLTCGKIFAVEILD 610
C+L + + PD ++V++ L + + I++
Sbjct: 1289 ---IPCQLHNTTPVGNVWQPDAIEVLQQLLSKRQVDIHIME 1326
Score = 30.4 bits (67), Expect = 9.6
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 6/61 (9%)
Query: 716 GKWLRVEITNVHSSRALD--VQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCL 773
G W R +I + L VQF+D G+ + ++ L +IP ++ P +AIK L
Sbjct: 1493 GLWYRAKIVAIKEFNPLSILVQFVDYGSTAKLTLNRLCQIP----SHLMRYPARAIKVLL 1548
Query: 774 A 774
A
Sbjct: 1549 A 1549
>gi|4502015 A-kinase anchor protein 1 precursor [Homo sapiens]
Length = 903
Score = 61.2 bits (147), Expect = 5e-09
Identities = 50/208 (24%), Positives = 96/208 (46%), Gaps = 14/208 (6%)
Query: 457 LMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNV 516
LM+P + V+VV N + ++ A ++ +M YS+ T V +
Sbjct: 702 LMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALRSLDQQMYLCYSQPGIPTLPTPVEI 761
Query: 517 GQLLAVNAEEDAWLRAQVIST--EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQA 574
+ A + AW RAQV+++ E N++++ YVDYG + V+ ++ F +L FQ
Sbjct: 762 TVICAAPGADGAWWRAQVVASYEETNEVEIRYVDYGGYKRVKVDVLRQIRSDFVTLPFQG 821
Query: 575 TKCKLAGLEVLSDD----PDLVKVVESLTCGKIFAVEI--LDKADIPLVVLYDTSGEDDI 628
+ L + LSDD P+ + +T ++ +PL+ L+ G++ +
Sbjct: 822 AEVLLDSVMPLSDDDQFSPEADAAMSEMTGNTALLAQVTSYSPTGLPLIQLWSVVGDEVV 881
Query: 629 NINATCLKAICDKSLEVHLQVDAMYTNV 656
IN +++ ++ L VD+ YT++
Sbjct: 882 LIN----RSLVERGLA--QWVDSYYTSL 903
>gi|169163653 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 59.3 bits (142), Expect = 2e-08
Identities = 81/334 (24%), Positives = 133/334 (39%), Gaps = 49/334 (14%)
Query: 492 ELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGF 551
+L+ ++++ YYS + +GQ V W RA V++ ++ + +VDYG+
Sbjct: 929 KLLMEQIQNYYSIHS-----DPYEIGQTACVAKYSGKWCRAAVLTQVSKEVDIVFVDYGY 983
Query: 552 SENVEKSKAYKLNPKFCSLSFQATKCKLAG-LEVLSDD---------PDLVKVVES---- 597
+ V +NP+F L QA +C L +E +S DL + S
Sbjct: 984 QKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPVSCKLFSWTRKAFRDLWNFISSSRGL 1043
Query: 598 LTCGKIFAVEILDKADIPLVV------------LYDTSGEDDININAT-----CLKAICD 640
LTC I+A+ I+ + +V L + I ++ T L + C
Sbjct: 1044 LTC-IIYALVIIHPNHLYNLVDLQSSFTSAKEFLMNRGSAQYITLSETFPSLFSLYSYCY 1102
Query: 641 KSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECF 700
S + + + V +++I S YCQ+ + L + KI + + ++
Sbjct: 1103 SSFNIQIGSE---EEVYISHIYSPQKFYCQLG-RNNKDLEMIETKITESVNLQNFPKYDS 1158
Query: 701 VSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQE 760
+ C I + G R SS V F+D G V + LR I +F E
Sbjct: 1159 NKMRVC--ISKYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQF-PE 1215
Query: 761 MIAIPPQAIKCCLADL-----PQSIGMWTPDAVL 789
++ P QAIKC L+DL P I W D L
Sbjct: 1216 LLFTPMQAIKCFLSDLRDVDIPAEISSWFKDNFL 1249
Score = 55.8 bits (133), Expect = 2e-07
Identities = 119/593 (20%), Positives = 222/593 (37%), Gaps = 111/593 (18%)
Query: 515 NVGQLLAVNAEEDAWLRAQVIST-EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQ 573
N G L W R + N++K+ ++DYG SE + KL F +
Sbjct: 437 NFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLF 496
Query: 574 ATKCKLAGLEVLSDDPDL--VKVVESLTCGKIFAVEILDKADIPLVVLYDTSGEDDININ 631
+ C L L D + + + + G++ I D + + Y T + +N
Sbjct: 497 SFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHI-DWFNKDECLYYVTLQTQESTVN 555
Query: 632 ATCL------KAICDKS-------------LEVH-LQVDAMYTNVK--VTNICSDGTLYC 669
+ CL + +C S +V+ V++ N++ + ++ G L
Sbjct: 556 SKCLLKTVGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNKKGILKV 615
Query: 670 QVPCKGL-----------------------------NKLSDLLRKIEDYFH-CKHMTSEC 699
P K + N+ ++++ I ++ C++ E
Sbjct: 616 GFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN--DEM 673
Query: 700 FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRF 757
+ P G C + ++ R IT ++ + ++V FLD G S+ +++ + P F
Sbjct: 674 ILRKPEPGLFCCARYSKDRRFYRAVITEINGYK-INVYFLDYGNTDSIPFFDVKILLPEF 732
Query: 758 LQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCS-----------DCSIKVT 806
+ +P A+ C LA + +WT A+ + + VLN + ++ +
Sbjct: 733 CE----LPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQ 788
Query: 807 KVDETRGIAHVYLFTPKNFPD---------PHRSINRQITNADLWKHQKDVFLSAISSGA 857
V+ + I + L + + P + N++ K IS+
Sbjct: 789 SVEASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSE--SKNKVNIKKVISALL 846
Query: 858 DSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFST---------EELPPPVHLS 908
+ P SK + S N EN NL+ + KS+ + S F P ++
Sbjct: 847 EGPKSKKYH---SNNLVEN---NLS--LPKSLAVNISEFKNPFTLSVGPESSWPYKEYIF 898
Query: 909 KPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAK 968
+PG ++V PG F Q + L++LME++ YYS+ + + + V AK
Sbjct: 899 RPGTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHSDPYEIGQTACV--AK 956
Query: 969 VENKWHRVLLKGILT--NGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQA 1019
KW R +LT + V + +DYG + V I + + F L QA
Sbjct: 957 YSGKWCRA---AVLTQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQA 1006
Score = 45.4 bits (106), Expect = 3e-04
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 656 VKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCK 715
VK + G CQ+ CK L L+ +I++Y+ E + C+
Sbjct: 906 VKCSCYYGPGDFSCQLQCKS-EDLKLLMEQIQNYYSIHSDPYEIGQTA------CVAKYS 958
Query: 716 GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCL 773
GKW R + S+ +D+ F+D G V + +L I PRFL + QA +CCL
Sbjct: 959 GKWCRAAVLT-QVSKEVDIVFVDYGYQKRVLIEDLCAINPRFL----LLESQAFRCCL 1011
Score = 40.8 bits (94), Expect = 0.007
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Query: 970 ENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC 1029
+N +R ++K IL V +DYG +VN K+ L F +P + A L+GVK
Sbjct: 1502 DNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKW 1561
Query: 1030 NQ----WSEEASMVFRNHVEKK 1047
N+ W ++ F + V K
Sbjct: 1562 NEPDEIWDDKTVDYFTSKVHNK 1583
Score = 38.9 bits (89), Expect = 0.027
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 7/93 (7%)
Query: 964 VYAAKVENKWHRVLLKGILTNGLVSVYELDYG------KHELVNIRKVQPLVDMFRKLPF 1017
++ K E++W+RV + + L V +DYG E++N++ V + +L +
Sbjct: 1934 LFKYKSEDQWNRVEISEVSPQSLCLVL-VDYGFSFYIRYSEIINLKVVPEELLNLPRLSY 1992
Query: 1018 QAVTAQLAGVKCNQWSEEASMVFRNHVEKKPLV 1050
+ + K WSEEA + FR+ + K LV
Sbjct: 1993 PCILYGILPAKGKHWSEEAKIFFRDFLSKPDLV 2025
Score = 37.4 bits (85), Expect = 0.079
Identities = 36/146 (24%), Positives = 62/146 (42%), Gaps = 6/146 (4%)
Query: 911 GEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYY-SVSEERHIAVEKDQVY--AA 967
G V V A P F Q + +LE L M L+Y +V +E + + A
Sbjct: 386 GSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVAR 445
Query: 968 KVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV 1027
+ +WHR +L+ +L V ++ +DYG E + V+ L F +P + L
Sbjct: 446 RRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLT-- 503
Query: 1028 KCNQWSEEASMVFRNHVEKKPLVALV 1053
C + + +F+ + K+ L+ V
Sbjct: 504 -CLHSPDRDARIFQLSIFKQALLGQV 528
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/94 (25%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 934 EIHKLEVLMEEMILYYSVSEERHI-----AVEKDQVYAAKVEN--KWHRVLLKGILTNGL 986
++ K + ++ ++I+ + E++ ++EK AK +N KWHR ++ +
Sbjct: 1691 KLSKNKKILSDLIVLITKEEKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDK 1750
Query: 987 VSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAV 1020
V V+ +D G +E+V + + L + R +P QAV
Sbjct: 1751 VLVFLVDCGIYEIVPVCNTKLLSNEIRNIPRQAV 1784
Score = 33.1 bits (74), Expect = 1.5
Identities = 30/145 (20%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 917 YVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQ-----VYAAKVEN 971
++ +P F ++ ++ + +M+ + +Y + E + + K + +
Sbjct: 633 FIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDR 692
Query: 972 KWHRVLLKGILTNGL-VSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--K 1028
+++R ++ I NG ++VY LDYG + + V+ L+ F +LP A+ LA +
Sbjct: 693 RFYRAVITEI--NGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPV 750
Query: 1029 CNQWSEEASMVFRNHVEKKPLVALV 1053
+ W++ A F+ V K ++ V
Sbjct: 751 EDLWTKAAIDYFKKLVLNKAILLQV 775
Score = 32.3 bits (72), Expect = 2.5
Identities = 40/159 (25%), Positives = 66/159 (41%), Gaps = 23/159 (14%)
Query: 463 ASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAV 522
++P+ ++L+ V+IR + A+ L E + + P+ VG L+
Sbjct: 1451 SNPANFHIQLAENESVIIRLADALNATARRLRERK---------SVKPL----VGDLVVA 1497
Query: 523 NAEEDAWLRAQVIST--EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLA 580
D + VI N +V ++DYG S V SK Y+L +F ++ L+
Sbjct: 1498 EYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLS 1557
Query: 581 GLEVLSDDPDLV---KVVESLTC---GKIFAVEILDKAD 613
G V ++PD + K V+ T K E L K D
Sbjct: 1558 G--VKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKKHD 1594
>gi|169164192 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 59.3 bits (142), Expect = 2e-08
Identities = 81/334 (24%), Positives = 133/334 (39%), Gaps = 49/334 (14%)
Query: 492 ELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGF 551
+L+ ++++ YYS + +GQ V W RA V++ ++ + +VDYG+
Sbjct: 929 KLLMEQIQNYYSIHS-----DPYEIGQTACVAKYSGKWCRAAVLTQVSKEVDIVFVDYGY 983
Query: 552 SENVEKSKAYKLNPKFCSLSFQATKCKLAG-LEVLSDD---------PDLVKVVES---- 597
+ V +NP+F L QA +C L +E +S DL + S
Sbjct: 984 QKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPVSCKLFSWTRKAFRDLWNFISSSRGL 1043
Query: 598 LTCGKIFAVEILDKADIPLVV------------LYDTSGEDDININAT-----CLKAICD 640
LTC I+A+ I+ + +V L + I ++ T L + C
Sbjct: 1044 LTC-IIYALVIIHPNHLYNLVDLQSSFTSAKEFLMNRGSAQYITLSETFPSLFSLYSYCY 1102
Query: 641 KSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECF 700
S + + + V +++I S YCQ+ + L + KI + + ++
Sbjct: 1103 SSFNIQIGSE---EEVYISHIYSPQKFYCQLG-RNNKDLEMIETKITESVNLQNFPKYDS 1158
Query: 701 VSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQE 760
+ C I + G R SS V F+D G V + LR I +F E
Sbjct: 1159 NKMRVC--ISKYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQF-PE 1215
Query: 761 MIAIPPQAIKCCLADL-----PQSIGMWTPDAVL 789
++ P QAIKC L+DL P I W D L
Sbjct: 1216 LLFTPMQAIKCFLSDLRDVDIPAEISSWFKDNFL 1249
Score = 55.8 bits (133), Expect = 2e-07
Identities = 119/593 (20%), Positives = 222/593 (37%), Gaps = 111/593 (18%)
Query: 515 NVGQLLAVNAEEDAWLRAQVIST-EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQ 573
N G L W R + N++K+ ++DYG SE + KL F +
Sbjct: 437 NFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLF 496
Query: 574 ATKCKLAGLEVLSDDPDL--VKVVESLTCGKIFAVEILDKADIPLVVLYDTSGEDDININ 631
+ C L L D + + + + G++ I D + + Y T + +N
Sbjct: 497 SFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHI-DWFNKDECLYYVTLQTQESTVN 555
Query: 632 ATCL------KAICDKS-------------LEVH-LQVDAMYTNVK--VTNICSDGTLYC 669
+ CL + +C S +V+ V++ N++ + ++ G L
Sbjct: 556 SKCLLKTVGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNKKGILKV 615
Query: 670 QVPCKGL-----------------------------NKLSDLLRKIEDYFH-CKHMTSEC 699
P K + N+ ++++ I ++ C++ E
Sbjct: 616 GFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN--DEM 673
Query: 700 FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRF 757
+ P G C + ++ R IT ++ + ++V FLD G S+ +++ + P F
Sbjct: 674 ILRKPEPGLFCCARYSKDRRFYRAVITEINGYK-INVYFLDYGNTDSIPFFDVKILLPEF 732
Query: 758 LQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCS-----------DCSIKVT 806
+ +P A+ C LA + +WT A+ + + VLN + ++ +
Sbjct: 733 CE----LPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQ 788
Query: 807 KVDETRGIAHVYLFTPKNFPD---------PHRSINRQITNADLWKHQKDVFLSAISSGA 857
V+ + I + L + + P + N++ K IS+
Sbjct: 789 SVEASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSE--SKNKVNIKKVISALL 846
Query: 858 DSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFST---------EELPPPVHLS 908
+ P SK + S N EN NL+ + KS+ + S F P ++
Sbjct: 847 EGPKSKKYH---SNNLVEN---NLS--LPKSLAVNISEFKNPFTLSVGPESSWPYKEYIF 898
Query: 909 KPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAK 968
+PG ++V PG F Q + L++LME++ YYS+ + + + V AK
Sbjct: 899 RPGTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHSDPYEIGQTACV--AK 956
Query: 969 VENKWHRVLLKGILT--NGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQA 1019
KW R +LT + V + +DYG + V I + + F L QA
Sbjct: 957 YSGKWCRA---AVLTQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQA 1006
Score = 45.4 bits (106), Expect = 3e-04
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 656 VKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCK 715
VK + G CQ+ CK L L+ +I++Y+ E + C+
Sbjct: 906 VKCSCYYGPGDFSCQLQCKS-EDLKLLMEQIQNYYSIHSDPYEIGQTA------CVAKYS 958
Query: 716 GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCL 773
GKW R + S+ +D+ F+D G V + +L I PRFL + QA +CCL
Sbjct: 959 GKWCRAAVLT-QVSKEVDIVFVDYGYQKRVLIEDLCAINPRFL----LLESQAFRCCL 1011
Score = 40.8 bits (94), Expect = 0.007
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Query: 970 ENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC 1029
+N +R ++K IL V +DYG +VN K+ L F +P + A L+GVK
Sbjct: 1502 DNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKW 1561
Query: 1030 NQ----WSEEASMVFRNHVEKK 1047
N+ W ++ F + V K
Sbjct: 1562 NEPDEIWDDKTVDYFTSKVHNK 1583
Score = 38.9 bits (89), Expect = 0.027
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 7/93 (7%)
Query: 964 VYAAKVENKWHRVLLKGILTNGLVSVYELDYG------KHELVNIRKVQPLVDMFRKLPF 1017
++ K E++W+RV + + L V +DYG E++N++ V + +L +
Sbjct: 1934 LFKYKSEDQWNRVEISEVSPQSLCLVL-VDYGFSFYIRYSEIINLKVVPEELLNLPRLSY 1992
Query: 1018 QAVTAQLAGVKCNQWSEEASMVFRNHVEKKPLV 1050
+ + K WSEEA + FR+ + K LV
Sbjct: 1993 PCILYGILPAKGKHWSEEAKIFFRDFLSKPDLV 2025
Score = 37.4 bits (85), Expect = 0.079
Identities = 36/146 (24%), Positives = 62/146 (42%), Gaps = 6/146 (4%)
Query: 911 GEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYY-SVSEERHIAVEKDQVY--AA 967
G V V A P F Q + +LE L M L+Y +V +E + + A
Sbjct: 386 GSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVAR 445
Query: 968 KVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV 1027
+ +WHR +L+ +L V ++ +DYG E + V+ L F +P + L
Sbjct: 446 RRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLT-- 503
Query: 1028 KCNQWSEEASMVFRNHVEKKPLVALV 1053
C + + +F+ + K+ L+ V
Sbjct: 504 -CLHSPDRDARIFQLSIFKQALLGQV 528
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/94 (25%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 934 EIHKLEVLMEEMILYYSVSEERHI-----AVEKDQVYAAKVEN--KWHRVLLKGILTNGL 986
++ K + ++ ++I+ + E++ ++EK AK +N KWHR ++ +
Sbjct: 1691 KLSKNKKILSDLIVLITKEEKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDK 1750
Query: 987 VSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAV 1020
V V+ +D G +E+V + + L + R +P QAV
Sbjct: 1751 VLVFLVDCGIYEIVPVCNTKLLSNEIRNIPRQAV 1784
Score = 33.1 bits (74), Expect = 1.5
Identities = 30/145 (20%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 917 YVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQ-----VYAAKVEN 971
++ +P F ++ ++ + +M+ + +Y + E + + K + +
Sbjct: 633 FIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDR 692
Query: 972 KWHRVLLKGILTNGL-VSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--K 1028
+++R ++ I NG ++VY LDYG + + V+ L+ F +LP A+ LA +
Sbjct: 693 RFYRAVITEI--NGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPV 750
Query: 1029 CNQWSEEASMVFRNHVEKKPLVALV 1053
+ W++ A F+ V K ++ V
Sbjct: 751 EDLWTKAAIDYFKKLVLNKAILLQV 775
Score = 32.3 bits (72), Expect = 2.5
Identities = 40/159 (25%), Positives = 66/159 (41%), Gaps = 23/159 (14%)
Query: 463 ASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAV 522
++P+ ++L+ V+IR + A+ L E + + P+ VG L+
Sbjct: 1451 SNPANFHIQLAENESVIIRLADALNATARRLRERK---------SVKPL----VGDLVVA 1497
Query: 523 NAEEDAWLRAQVIST--EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLA 580
D + VI N +V ++DYG S V SK Y+L +F ++ L+
Sbjct: 1498 EYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLS 1557
Query: 581 GLEVLSDDPDLV---KVVESLTC---GKIFAVEILDKAD 613
G V ++PD + K V+ T K E L K D
Sbjct: 1558 G--VKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKKHD 1594
>gi|169163210 PREDICTED: similar to tudor domain containing 1 [Homo
sapiens]
Length = 2080
Score = 59.3 bits (142), Expect = 2e-08
Identities = 81/334 (24%), Positives = 133/334 (39%), Gaps = 49/334 (14%)
Query: 492 ELMEDEMKEYYSKNPKITPVQAVNVGQLLAVNAEEDAWLRAQVISTEENKIKVCYVDYGF 551
+L+ ++++ YYS + +GQ V W RA V++ ++ + +VDYG+
Sbjct: 929 KLLMEQIQNYYSIHS-----DPYEIGQTACVAKYSGKWCRAAVLTQVSKEVDIVFVDYGY 983
Query: 552 SENVEKSKAYKLNPKFCSLSFQATKCKLAG-LEVLSDD---------PDLVKVVES---- 597
+ V +NP+F L QA +C L +E +S DL + S
Sbjct: 984 QKRVLIEDLCAINPRFLLLESQAFRCCLNHFIEPVSCKLFSWTRKAFRDLWNFISSSRGL 1043
Query: 598 LTCGKIFAVEILDKADIPLVV------------LYDTSGEDDININAT-----CLKAICD 640
LTC I+A+ I+ + +V L + I ++ T L + C
Sbjct: 1044 LTC-IIYALVIIHPNHLYNLVDLQSSFTSAKEFLMNRGSAQYITLSETFPSLFSLYSYCY 1102
Query: 641 KSLEVHLQVDAMYTNVKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECF 700
S + + + V +++I S YCQ+ + L + KI + + ++
Sbjct: 1103 SSFNIQIGSE---EEVYISHIYSPQKFYCQLG-RNNKDLEMIETKITESVNLQNFPKYDS 1158
Query: 701 VSLPFCGKICLFHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQE 760
+ C I + G R SS V F+D G V + LR I +F E
Sbjct: 1159 NKMRVC--ISKYVEDGLSYRALAIPTDSSSEFQVYFVDFGNKQLVGENMLRAISAQF-PE 1215
Query: 761 MIAIPPQAIKCCLADL-----PQSIGMWTPDAVL 789
++ P QAIKC L+DL P I W D L
Sbjct: 1216 LLFTPMQAIKCFLSDLRDVDIPAEISSWFKDNFL 1249
Score = 55.8 bits (133), Expect = 2e-07
Identities = 119/593 (20%), Positives = 222/593 (37%), Gaps = 111/593 (18%)
Query: 515 NVGQLLAVNAEEDAWLRAQVIST-EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQ 573
N G L W R + N++K+ ++DYG SE + KL F +
Sbjct: 437 NFGLLCVARRRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLF 496
Query: 574 ATKCKLAGLEVLSDDPDL--VKVVESLTCGKIFAVEILDKADIPLVVLYDTSGEDDININ 631
+ C L L D + + + + G++ I D + + Y T + +N
Sbjct: 497 SFPCSLTCLHSPDRDARIFQLSIFKQALLGQVVYAHI-DWFNKDECLYYVTLQTQESTVN 555
Query: 632 ATCL------KAICDKS-------------LEVH-LQVDAMYTNVK--VTNICSDGTLYC 669
+ CL + +C S +V+ V++ N++ + ++ G L
Sbjct: 556 SKCLLKTVGTQVLCPMSDSKISNILSETSVSDVNSFAVESFMGNIEWSIDSLNKKGILKV 615
Query: 670 QVPCKGL-----------------------------NKLSDLLRKIEDYFH-CKHMTSEC 699
P K + N+ ++++ I ++ C++ E
Sbjct: 616 GFPIKTVQMEIEAAYIAFIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCEN--DEM 673
Query: 700 FVSLPFCGKICL--FHCKGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRF 757
+ P G C + ++ R IT ++ + ++V FLD G S+ +++ + P F
Sbjct: 674 ILRKPEPGLFCCARYSKDRRFYRAVITEINGYK-INVYFLDYGNTDSIPFFDVKILLPEF 732
Query: 758 LQEMIAIPPQAIKCCLADLPQSIGMWTPDAVLWLRDSVLNCS-----------DCSIKVT 806
+ +P A+ C LA + +WT A+ + + VLN + ++ +
Sbjct: 733 CE----LPALAMCCSLAHIFPVEDLWTKAAIDYFKKLVLNKAILLQVIAKKDDKYTVNIQ 788
Query: 807 KVDETRGIAHVYLFTPKNFPD---------PHRSINRQITNADLWKHQKDVFLSAISSGA 857
V+ + I + L + + P + N++ K IS+
Sbjct: 789 SVEASENIDVISLMLQAGYAEYFQVELEYFPKSVSEYSMLNSE--SKNKVNIKKVISALL 846
Query: 858 DSPNSKNGNMPMSGNTGENFRKNLTDVIKKSMVDHTSAFST---------EELPPPVHLS 908
+ P SK + S N EN NL+ + KS+ + S F P ++
Sbjct: 847 EGPKSKKYH---SNNLVEN---NLS--LPKSLAVNISEFKNPFTLSVGPESSWPYKEYIF 898
Query: 909 KPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQVYAAK 968
+PG ++V PG F Q + L++LME++ YYS+ + + + V AK
Sbjct: 899 RPGTVLEVKCSCYYGPGDFSCQLQCKSEDLKLLMEQIQNYYSIHSDPYEIGQTACV--AK 956
Query: 969 VENKWHRVLLKGILT--NGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQA 1019
KW R +LT + V + +DYG + V I + + F L QA
Sbjct: 957 YSGKWCRA---AVLTQVSKEVDIVFVDYGYQKRVLIEDLCAINPRFLLLESQA 1006
Score = 45.4 bits (106), Expect = 3e-04
Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 12/118 (10%)
Query: 656 VKVTNICSDGTLYCQVPCKGLNKLSDLLRKIEDYFHCKHMTSECFVSLPFCGKICLFHCK 715
VK + G CQ+ CK L L+ +I++Y+ E + C+
Sbjct: 906 VKCSCYYGPGDFSCQLQCKS-EDLKLLMEQIQNYYSIHSDPYEIGQTA------CVAKYS 958
Query: 716 GKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIKCCL 773
GKW R + S+ +D+ F+D G V + +L I PRFL + QA +CCL
Sbjct: 959 GKWCRAAVLT-QVSKEVDIVFVDYGYQKRVLIEDLCAINPRFL----LLESQAFRCCL 1011
Score = 40.8 bits (94), Expect = 0.007
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 4/82 (4%)
Query: 970 ENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVKC 1029
+N +R ++K IL V +DYG +VN K+ L F +P + A L+GVK
Sbjct: 1502 DNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLSGVKW 1561
Query: 1030 NQ----WSEEASMVFRNHVEKK 1047
N+ W ++ F + V K
Sbjct: 1562 NEPDEIWDDKTVDYFTSKVHNK 1583
Score = 38.9 bits (89), Expect = 0.027
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 7/93 (7%)
Query: 964 VYAAKVENKWHRVLLKGILTNGLVSVYELDYG------KHELVNIRKVQPLVDMFRKLPF 1017
++ K E++W+RV + + L V +DYG E++N++ V + +L +
Sbjct: 1934 LFKYKSEDQWNRVEISEVSPQSLCLVL-VDYGFSFYIRYSEIINLKVVPEELLNLPRLSY 1992
Query: 1018 QAVTAQLAGVKCNQWSEEASMVFRNHVEKKPLV 1050
+ + K WSEEA + FR+ + K LV
Sbjct: 1993 PCILYGILPAKGKHWSEEAKIFFRDFLSKPDLV 2025
Score = 37.4 bits (85), Expect = 0.079
Identities = 36/146 (24%), Positives = 62/146 (42%), Gaps = 6/146 (4%)
Query: 911 GEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEEMILYY-SVSEERHIAVEKDQVY--AA 967
G V V A P F Q + +LE L M L+Y +V +E + + A
Sbjct: 386 GSTESVKVSSALSPSKFYCQLIKWTPELENLTAHMTLHYDTVCQETSPTCDNFGLLCVAR 445
Query: 968 KVENKWHRVLLKGILTNGLVSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV 1027
+ +WHR +L+ +L V ++ +DYG E + V+ L F +P + L
Sbjct: 446 RRNGQWHRGILQQLLPPNQVKIWFMDYGSSEAIPSIYVKKLKQDFILVPLFSFPCSLT-- 503
Query: 1028 KCNQWSEEASMVFRNHVEKKPLVALV 1053
C + + +F+ + K+ L+ V
Sbjct: 504 -CLHSPDRDARIFQLSIFKQALLGQV 528
Score = 33.5 bits (75), Expect = 1.1
Identities = 24/94 (25%), Positives = 49/94 (52%), Gaps = 7/94 (7%)
Query: 934 EIHKLEVLMEEMILYYSVSEERHI-----AVEKDQVYAAKVEN--KWHRVLLKGILTNGL 986
++ K + ++ ++I+ + E++ ++EK AK +N KWHR ++ +
Sbjct: 1691 KLSKNKKILSDLIVLITKEEKKSPFLSMESIEKGLECLAKSKNTLKWHRSKVEEKYVDDK 1750
Query: 987 VSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAV 1020
V V+ +D G +E+V + + L + R +P QAV
Sbjct: 1751 VLVFLVDCGIYEIVPVCNTKLLSNEIRNIPRQAV 1784
Score = 33.1 bits (74), Expect = 1.5
Identities = 30/145 (20%), Positives = 67/145 (46%), Gaps = 10/145 (6%)
Query: 917 YVPVACHPGYFVIQPWQEIHKLEVLMEEMILYYSVSEERHIAVEKDQ-----VYAAKVEN 971
++ +P F ++ ++ + +M+ + +Y + E + + K + +
Sbjct: 633 FIAYVLNPSNFWVRTNDHRNEFQEIMKNINKFYDLCENDEMILRKPEPGLFCCARYSKDR 692
Query: 972 KWHRVLLKGILTNGL-VSVYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGV--K 1028
+++R ++ I NG ++VY LDYG + + V+ L+ F +LP A+ LA +
Sbjct: 693 RFYRAVITEI--NGYKINVYFLDYGNTDSIPFFDVKILLPEFCELPALAMCCSLAHIFPV 750
Query: 1029 CNQWSEEASMVFRNHVEKKPLVALV 1053
+ W++ A F+ V K ++ V
Sbjct: 751 EDLWTKAAIDYFKKLVLNKAILLQV 775
Score = 32.3 bits (72), Expect = 2.5
Identities = 40/159 (25%), Positives = 66/159 (41%), Gaps = 23/159 (14%)
Query: 463 ASPSVLVVELSNTNEVVIRYVGKDYSAAQELMEDEMKEYYSKNPKITPVQAVNVGQLLAV 522
++P+ ++L+ V+IR + A+ L E + + P+ VG L+
Sbjct: 1451 SNPANFHIQLAENESVIIRLADALNATARRLRERK---------SVKPL----VGDLVVA 1497
Query: 523 NAEEDAWLRAQVIST--EENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLA 580
D + VI N +V ++DYG S V SK Y+L +F ++ L+
Sbjct: 1498 EYSGDNAIYRAVIKKILPGNSFEVEFIDYGNSAIVNTSKIYELQREFLTVPQLGIHAFLS 1557
Query: 581 GLEVLSDDPDLV---KVVESLTC---GKIFAVEILDKAD 613
G V ++PD + K V+ T K E L K D
Sbjct: 1558 G--VKWNEPDEIWDDKTVDYFTSKVHNKTVYCEFLKKHD 1594
>gi|77404397 staphylococcal nuclease domain containing 1 [Homo
sapiens]
Length = 910
Score = 45.8 bits (107), Expect = 2e-04
Identities = 40/149 (26%), Positives = 67/149 (44%), Gaps = 4/149 (2%)
Query: 454 VPPLMIPTEASPSVLVVELSNTNEVVIRYVGKDYSAAQ-ELMEDEMKEYYSKNPKITPVQ 512
V P++ E S S V ++ + + YV + Q E + + M+ + +P +
Sbjct: 669 VMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSY 728
Query: 513 AVNVGQLLAVNAEEDAWLRAQVISTEEN-KIKVCYVDYGFSENVEKSKAYKLNPKFCS-- 569
A G+ + W RA+V E KI V Y+DYG E + ++ L+P F +
Sbjct: 729 APRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLSPAFSTRV 788
Query: 570 LSFQATKCKLAGLEVLSDDPDLVKVVESL 598
L QAT+ A ++V DD V+S+
Sbjct: 789 LPAQATEYAFAFIQVPQDDDARTDAVDSV 817
Score = 36.6 bits (83), Expect = 0.13
Identities = 35/152 (23%), Positives = 65/152 (42%), Gaps = 6/152 (3%)
Query: 886 KKSMVDHTSAFSTEELPPPVH-LSKPGEHMDVYVPVACHPGYFVIQPWQEIHKLEVLMEE 944
K+ + H EE+ P + + + V+V +F +Q + +LE LME
Sbjct: 654 KEKVWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMEN 713
Query: 945 M---ILYYSVSEERHIAVEKDQVYAAKVENKWHRVLLKGILTNGLVSVYELDYGKHELVN 1001
M I + E + + A V+ +W+R ++ + + + V+ +DYG E++
Sbjct: 714 MRNDIASHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLP 773
Query: 1002 IRKVQPLVDMF--RKLPFQAVTAQLAGVKCNQ 1031
++ L F R LP QA A ++ Q
Sbjct: 774 STRLGTLSPAFSTRVLPAQATEYAFAFIQVPQ 805
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 37.0 bits (84), Expect = 0.10
Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 9/78 (11%)
Query: 525 EEDAWLRAQVISTEENKIKVCYVDYGFSENVEKSKAYKLNPKFCSLSFQATKCKLAGLEV 584
++ + RAQV+ N +V +VDYG +V+ ++ +F L FQA + K+ +
Sbjct: 959 DKQRYFRAQVLYVSGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKMR- 1017
Query: 585 LSDDPDLVKVVESLTCGK 602
+SL CGK
Sbjct: 1018 --------PSAKSLVCGK 1027
Score = 32.0 bits (71), Expect = 3.3
Identities = 29/112 (25%), Positives = 52/112 (46%), Gaps = 14/112 (12%)
Query: 715 KGKWLRVEITNVHSSRALDVQFLDSGTVTSVKVSELREIPPRFLQEMIAIPPQAIK---C 771
K ++ R ++ V S + +V F+D G + V + L EIP +FL+ +P QA++ C
Sbjct: 960 KQRYFRAQVLYV-SGNSAEVFFVDYGNKSHVDLHLLMEIPCQFLE----LPFQALEFKIC 1014
Query: 772 CLADLPQSI---GMWTPDAVLWLRDSVLNCSDCSIKVTKVDETRGIAHVYLF 820
+ +S+ W+ A W V S C++ V + HV ++
Sbjct: 1015 KMRPSAKSLVCGKHWSDGASQWFASLV---SGCTLLVKVFSVVHSVLHVDVY 1063
Score = 31.2 bits (69), Expect = 5.6
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 8/79 (10%)
Query: 989 VYELDYGKHELVNIRKVQPLVDMFRKLPFQAVTAQLAGVK-------CNQ-WSEEASMVF 1040
V+ +DYG V++ + + F +LPFQA+ ++ ++ C + WS+ AS F
Sbjct: 978 VFFVDYGNKSHVDLHLLMEIPCQFLELPFQALEFKICKMRPSAKSLVCGKHWSDGASQWF 1037
Query: 1041 RNHVEKKPLVALVQTVIEN 1059
+ V L+ V +V+ +
Sbjct: 1038 ASLVSGCTLLVKVFSVVHS 1056
>gi|49472835 bridging integrator 2 [Homo sapiens]
Length = 565
Score = 35.8 bits (81), Expect = 0.23
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 410 TDKIQKDAGQAHGDNDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEASPSVLV 469
T+ + DA Q +++IK ++E+E ++ E S A S+ ED +P P +A PS
Sbjct: 296 TEDLAPDAAQGEDNSEIKELLEEEEIEKEGSEASSSE---EDEPLPACNGPAQAQPSPTT 352
Query: 470 VELSNTNEVV 479
+ EV+
Sbjct: 353 ERAKSQEEVL 362
>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 1 [Homo sapiens]
Length = 1075
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 282 HICTVEKPCSGGQDLLLYPAKRKQLLRSELDTEKVPLSPLPGPKQT---PPLKGC--PTV 336
++C ++ S Q P KQ R E+D VP P+P P QT GC +V
Sbjct: 681 YLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSV 740
Query: 337 MAGDFKEKVADLLVKYTSGLWASALPK 363
++G + + + Y S + +S LP+
Sbjct: 741 LSGQ-RSLICSIPQTYASMVTSSHLPQ 766
>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 4 [Homo sapiens]
Length = 1045
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 282 HICTVEKPCSGGQDLLLYPAKRKQLLRSELDTEKVPLSPLPGPKQT---PPLKGC--PTV 336
++C ++ S Q P KQ R E+D VP P+P P QT GC +V
Sbjct: 681 YLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSV 740
Query: 337 MAGDFKEKVADLLVKYTSGLWASALPK 363
++G + + + Y S + +S LP+
Sbjct: 741 LSGQ-RSLICSIPQTYASMVTSSHLPQ 766
>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 3 [Homo sapiens]
Length = 1065
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 282 HICTVEKPCSGGQDLLLYPAKRKQLLRSELDTEKVPLSPLPGPKQT---PPLKGC--PTV 336
++C ++ S Q P KQ R E+D VP P+P P QT GC +V
Sbjct: 681 YLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSV 740
Query: 337 MAGDFKEKVADLLVKYTSGLWASALPK 363
++G + + + Y S + +S LP+
Sbjct: 741 LSGQ-RSLICSIPQTYASMVTSSHLPQ 766
>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
calcineurin-dependent 3 isoform 2 [Homo sapiens]
Length = 1068
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 6/87 (6%)
Query: 282 HICTVEKPCSGGQDLLLYPAKRKQLLRSELDTEKVPLSPLPGPKQT---PPLKGC--PTV 336
++C ++ S Q P KQ R E+D VP P+P P QT GC +V
Sbjct: 681 YLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSV 740
Query: 337 MAGDFKEKVADLLVKYTSGLWASALPK 363
++G + + + Y S + +S LP+
Sbjct: 741 LSGQ-RSLICSIPQTYASMVTSSHLPQ 766
>gi|9961250 ATP-binding cassette, subfamily B, member 4 isoform B
[Homo sapiens]
Length = 1286
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 8/116 (6%)
Query: 551 FSENVEKSKAYKLNPKFCSLSF----QATKCKLAGLEVLSDDPDLVKVVESLTCGKIFAV 606
FSE K + K N +F + F +A L GL + V +V S CGK V
Sbjct: 380 FSERGHKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTV 439
Query: 607 EILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTNIC 662
+++ + P + G+D N N L+ I + V Q +++ NIC
Sbjct: 440 QLIQRLYDPDEGTINIDGQDIRNFNVNYLREI----IGVVSQEPVLFSTTIAENIC 491
>gi|9961252 ATP-binding cassette, subfamily B, member 4 isoform C
[Homo sapiens]
Length = 1232
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 8/116 (6%)
Query: 551 FSENVEKSKAYKLNPKFCSLSF----QATKCKLAGLEVLSDDPDLVKVVESLTCGKIFAV 606
FSE K + K N +F + F +A L GL + V +V S CGK V
Sbjct: 380 FSERGHKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTV 439
Query: 607 EILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTNIC 662
+++ + P + G+D N N L+ I + V Q +++ NIC
Sbjct: 440 QLIQRLYDPDEGTINIDGQDIRNFNVNYLREI----IGVVSQEPVLFSTTIAENIC 491
>gi|4505771 ATP-binding cassette, subfamily B, member 4 isoform A
[Homo sapiens]
Length = 1279
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 8/116 (6%)
Query: 551 FSENVEKSKAYKLNPKFCSLSF----QATKCKLAGLEVLSDDPDLVKVVESLTCGKIFAV 606
FSE K + K N +F + F +A L GL + V +V S CGK V
Sbjct: 380 FSERGHKPDSIKGNLEFNDVHFSYPSRANVKILKGLNLKVQSGQTVALVGSSGCGKSTTV 439
Query: 607 EILDKADIPLVVLYDTSGEDDININATCLKAICDKSLEVHLQVDAMYTNVKVTNIC 662
+++ + P + G+D N N L+ I + V Q +++ NIC
Sbjct: 440 QLIQRLYDPDEGTINIDGQDIRNFNVNYLREI----IGVVSQEPVLFSTTIAENIC 491
>gi|188497683 FAST kinase domains 1 [Homo sapiens]
Length = 847
Score = 33.5 bits (75), Expect = 1.1
Identities = 35/164 (21%), Positives = 68/164 (41%), Gaps = 12/164 (7%)
Query: 180 HVTMSTNNRFSPKASLQPPLQMHLSRTSTKEM---SDNLNQTVEKPNVKPPASYTYKMDE 236
H + T S + L + +SR +++ ++ L T++ V S +
Sbjct: 181 HRNLETTQDLSSLSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRN 240
Query: 237 VQNRIKEILNKHNNGIWISKLPHFYKELYKEDLNQGILQQFEHWPHICTVEKPCSGGQDL 296
V+ R + +L + NN +++S + H + + L+ QF + I +K + L
Sbjct: 241 VRYRYQPLLERCNN-VFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPL 299
Query: 297 LLYPAKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGD 340
+PA +L V L P+ GP++ LK +M+ D
Sbjct: 300 CNHPASFVKLF--------VALGPIAGPEEKKQLKSTMLLMSED 335
>gi|110349786 Alstrom syndrome 1 [Homo sapiens]
Length = 4169
Score = 33.1 bits (74), Expect = 1.5
Identities = 48/191 (25%), Positives = 72/191 (37%), Gaps = 21/191 (10%)
Query: 297 LLYPAKRKQLLRSELDTEKVPLSPLPGPKQTPPLKGCPTVMAGDFKEKVADLLVKYTSGL 356
+LYP + L S L E + +S + GP G PTV + + + LLV Y L
Sbjct: 773 ILYP---QDLADSHLPEEGLKVSAVAGPADQKT--GLPTVPSSAYSHR-EKLLVFYQQAL 826
Query: 357 WASALPKAFEEMYKVKFPEDALKNLASLSDVCSIDYISGNPQKAILYAKLP---LPTDKI 413
S LP+ ++ V P D +++ S G A LP L + +
Sbjct: 827 LDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEAL 886
Query: 414 QKDAGQAHGD--NDIKAMVEQEYLQVEESIAESANTFMEDITVPPLMIPTEA----SPSV 467
+ GD I + Y E+ I S T+P + P EA + SV
Sbjct: 887 KVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQ------TLPDFLFPEEALKVSAVSV 940
Query: 468 LVVELSNTNEV 478
L + + T V
Sbjct: 941 LAAQKTGTPTV 951
>gi|66571327 ring finger protein 213 [Homo sapiens]
Length = 3280
Score = 33.1 bits (74), Expect = 1.5
Identities = 24/105 (22%), Positives = 53/105 (50%), Gaps = 14/105 (13%)
Query: 885 IKKSMVDHTSAFS-TEELPPPVHLSKPGEHMDVYVPVACH---PGYFVIQPWQEIHKLEV 940
++ S+++ TSA+S +EL HL + G + Y P + ++ QE+ ++ +
Sbjct: 2251 LEDSILEKTSAYSRNDELN---HLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRL 2307
Query: 941 LMEEMILYYS-------VSEERHIAVEKDQVYAAKVENKWHRVLL 978
++ + S +++E+ +++ + + +VEN WHRV L
Sbjct: 2308 CLDRAADFLSEPEGGPEMAKEKQCYLQQVKQFCIRVENDWHRVYL 2352
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 32.7 bits (73), Expect = 1.9
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 177 VQRHVTMSTN-NRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNVKPPASYTYKMD 235
V RH TM +N ++ + K L Q+H +R + L +T + K A + ++D
Sbjct: 560 VSRHETMGSNISQLTDKNELLTE-QVHKARVKFNTLKGKLRETRDALREKTLALESVQLD 618
Query: 236 --EVQNRIKEILNKHNNG 251
+ Q+RIKE+ H NG
Sbjct: 619 LKQAQHRIKEMKQMHPNG 636
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 32.7 bits (73), Expect = 1.9
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 177 VQRHVTMSTN-NRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNVKPPASYTYKMD 235
V RH TM +N ++ + K L Q+H +R + L +T + K A + ++D
Sbjct: 589 VSRHETMGSNISQLTDKNELLTE-QVHKARVKFNTLKGKLRETRDALREKTLALESVQLD 647
Query: 236 --EVQNRIKEILNKHNNG 251
+ Q+RIKE+ H NG
Sbjct: 648 LKQAQHRIKEMKQMHPNG 665
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 32.7 bits (73), Expect = 1.9
Identities = 24/78 (30%), Positives = 39/78 (50%), Gaps = 4/78 (5%)
Query: 177 VQRHVTMSTN-NRFSPKASLQPPLQMHLSRTSTKEMSDNLNQTVEKPNVKPPASYTYKMD 235
V RH TM +N ++ + K L Q+H +R + L +T + K A + ++D
Sbjct: 589 VSRHETMGSNISQLTDKNELLTE-QVHKARVKFNTLKGKLRETRDALREKTLALESVQLD 647
Query: 236 --EVQNRIKEILNKHNNG 251
+ Q+RIKE+ H NG
Sbjct: 648 LKQAQHRIKEMKQMHPNG 665
>gi|62899047 RAD50 interactor 1 [Homo sapiens]
Length = 792
Score = 32.7 bits (73), Expect = 1.9
Identities = 36/136 (26%), Positives = 56/136 (41%), Gaps = 17/136 (12%)
Query: 209 KEMSDNLNQTVEKPNVKPPASYTYKMDEVQNRIKEILNKHNNGIWISKLPHFYKELYKED 268
+E+SDN+ Q + NV AS M E+ +++E H G ++ F+ ++ K+
Sbjct: 169 EELSDNIQQYLMTNNVPEAASTLVSMAELDIKLQESSCTHLLG-FMRATVKFWHKILKDK 227
Query: 269 LN---QGILQQFEHWPHICT-------VEKPCSGGQDLLLYPAKRKQLLRSELDTEKVPL 318
L + IL Q HWP I + +P S + QLL+ + E
Sbjct: 228 LTSDFEEILAQL-HWPFIAPPQSQTVGLSRPASAPEIYSYLETLFCQLLKLQTSDEL--- 283
Query: 319 SPLPGPKQTPPLKGCP 334
L PKQ P P
Sbjct: 284 --LTEPKQLPEKYSLP 297
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,652,347
Number of Sequences: 37866
Number of extensions: 1961137
Number of successful extensions: 5338
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 5186
Number of HSP's gapped (non-prelim): 145
length of query: 1098
length of database: 18,247,518
effective HSP length: 113
effective length of query: 985
effective length of database: 13,968,660
effective search space: 13759130100
effective search space used: 13759130100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.