Guide to the Human Genome
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Search of human proteins with 169214360

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169214360 PREDICTED: similar to mCG2980 isoform 1 [Homo
sapiens]
         (307 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169213941 PREDICTED: similar to mCG2980 [Homo sapiens]             626   e-180
gi|169214360 PREDICTED: similar to mCG2980 isoform 1 [Homo sapiens]   626   e-180
gi|169213374 PREDICTED: similar to mCG2980 isoform 1 [Homo sapiens]   626   e-180
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    60   2e-09
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    60   2e-09
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    59   4e-09
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    59   4e-09
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]            59   5e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    57   2e-08
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    56   4e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    56   5e-08
gi|148746195 trichohyalin [Homo sapiens]                               55   6e-08
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    55   1e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    55   1e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    52   5e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    51   1e-06
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    51   1e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            50   2e-06
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    50   3e-06
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti...    50   3e-06
gi|94721321 coiled-coil domain containing 11 [Homo sapiens]            49   6e-06
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             48   1e-05
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]            48   1e-05
gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]            48   1e-05
gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]            48   1e-05
gi|148746183 ubiquitin specific protease 35 [Homo sapiens]             48   1e-05
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       47   2e-05
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       47   2e-05
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        47   2e-05
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        47   2e-05

>gi|169213941 PREDICTED: similar to mCG2980 [Homo sapiens]
          Length = 307

 Score =  626 bits (1615), Expect = e-180
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60
           MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG
Sbjct: 1   MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60

Query: 61  DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120
           DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK
Sbjct: 61  DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120

Query: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180
           GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE
Sbjct: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180

Query: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240
           KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ
Sbjct: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240

Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300
           GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG
Sbjct: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300

Query: 301 EQLRREG 307
           EQLRREG
Sbjct: 301 EQLRREG 307


>gi|169214360 PREDICTED: similar to mCG2980 isoform 1 [Homo sapiens]
          Length = 307

 Score =  626 bits (1615), Expect = e-180
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60
           MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG
Sbjct: 1   MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60

Query: 61  DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120
           DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK
Sbjct: 61  DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120

Query: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180
           GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE
Sbjct: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180

Query: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240
           KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ
Sbjct: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240

Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300
           GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG
Sbjct: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300

Query: 301 EQLRREG 307
           EQLRREG
Sbjct: 301 EQLRREG 307


>gi|169213374 PREDICTED: similar to mCG2980 isoform 1 [Homo sapiens]
          Length = 307

 Score =  626 bits (1615), Expect = e-180
 Identities = 307/307 (100%), Positives = 307/307 (100%)

Query: 1   MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60
           MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG
Sbjct: 1   MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60

Query: 61  DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120
           DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK
Sbjct: 61  DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120

Query: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180
           GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE
Sbjct: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180

Query: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240
           KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ
Sbjct: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240

Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300
           GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG
Sbjct: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300

Query: 301 EQLRREG 307
           EQLRREG
Sbjct: 301 EQLRREG 307


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 52/194 (26%), Positives = 88/194 (45%), Gaps = 27/194 (13%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--EEEEKEERK 185
           K QE  K    QE + +EEE + ER  K   +E+ +R Q  +   QEE+  E+EEKE ++
Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 490

Query: 186 RGPMETFEDLWQ------------------RHLENGGDLQKRV--AEKASDKETAQFQAE 225
           +   E  E LW+                  R  E     +K++   EK  ++E   ++ E
Sbjct: 491 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550

Query: 226 EKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEV--E 283
           EK   +   ++ +W   ER   + +E          +   E R  + E   REE+E+  E
Sbjct: 551 EK---MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607

Query: 284 QLEHLRDELKKVTE 297
           Q E ++++ +K+ E
Sbjct: 608 QEEKMQEQEEKMQE 621



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 48/201 (23%), Positives = 98/201 (48%), Gaps = 17/201 (8%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
           EEK     +  +++ GKMR  +E    +E+ + E+  + E++EQ   ++  ++L ++E++
Sbjct: 292 EEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQ--EKELREQEKELREQKELREQEEQ 349

Query: 178 EEEKEER---KRGPMETFEDLWQRHLENGGDLQKRVAE---KASDKETAQFQAEEK---G 228
            +E+EE+   +   M   E+   R  E   + +K++ E   K  D+E   ++ +E+    
Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409

Query: 229 VRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHL 288
              +     +W+  E+    R E          + + E  QE+E   ERE+K  E+ E +
Sbjct: 410 EERMREQEKMWEQVEK---MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466

Query: 289 RDE---LKKVTETLGEQLRRE 306
           R++   ++K  E + EQ  +E
Sbjct: 467 REQEEKMQKQEENMWEQEEKE 487



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 44/189 (23%), Positives = 84/189 (44%), Gaps = 14/189 (7%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE----------DE 177
           K QE  K    QE +  EEE + ER  K   +E+ +R Q  +   QEE          ++
Sbjct: 570 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ 629

Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237
           EE+ +E++    E  E +W++  E   + Q+   +K    E  + Q +EK   +   +  
Sbjct: 630 EEKMQEQEEKMWEQEEKMWEQE-EKMWEQQRLPEQKEKLWEHEKMQEQEK---MQEQEEK 685

Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
           +W+  +     + ++         + E   R+ +++  E EE   EQ E ++++ +K+ E
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745

Query: 298 TLGEQLRRE 306
              E   +E
Sbjct: 746 QEEEMWEQE 754



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 45/184 (24%), Positives = 88/184 (47%), Gaps = 15/184 (8%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEE-VAERTHKSEVQEQAIRMQGHRQLHQEE- 175
           EE+ +   + K +E  +M   QE + +E+EE + E+  K   QE+ ++ Q  +   QEE 
Sbjct: 587 EEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEK 646

Query: 176 --DEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLG 233
             ++EE+  E++R P E  E LW+       +  +   EK  ++E  + + +E+      
Sbjct: 647 MWEQEEKMWEQQRLP-EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ------ 699

Query: 234 GDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELK 293
            ++  W   +       E +        + E   R+++E+  E+EEK  EQ E + ++ +
Sbjct: 700 -EKKTWDQEKM---REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755

Query: 294 KVTE 297
           K+ E
Sbjct: 756 KMWE 759



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 11/178 (6%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE---DEEEEKEER 184
           K +E   MR  ++   EEEE + E+  K + QE+ ++ Q      QEE   ++EE+  E+
Sbjct: 708 KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767

Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEK----GVRVLGGDRSLWQ 240
           +R P E  E LW+       +      EK  D+E      EEK      ++ G +  +W 
Sbjct: 768 QRLP-EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG 826

Query: 241 GAERGGGERREDLPHHHH---HHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKV 295
             E+  G+  +             + E + + ++E+  E+EEK   Q E +R++ +K+
Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKM 884



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 47/184 (25%), Positives = 86/184 (46%), Gaps = 22/184 (11%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED-EEEEKEERKRG 187
           +++  K+R  +E    +EE + E+  K   QE+ +  Q  R   QE++  E+EKE R++ 
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK 341

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
            +   E+  Q   E   + +    EK  ++E   ++ EE+          LW+  E+   
Sbjct: 342 ELREQEEQMQEQEEKMWEQE----EKMREQEEKMWRQEER----------LWE-QEKQMR 386

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELK-----KVTETLGEQ 302
           E+ + +        + + E  +EKEE    +EK  EQ+E +R+E K     K T    E+
Sbjct: 387 EQEQKMRDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445

Query: 303 LRRE 306
           ++ E
Sbjct: 446 MQEE 449



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 42/167 (25%), Positives = 78/167 (46%), Gaps = 7/167 (4%)

Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPM 189
           ++  KMR  +E    +EE + E+  +   QEQ +R Q  R   Q+E    EKEER R   
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE-RLREKEERMREQE 417

Query: 190 ETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGER 249
           + +E + +   E     Q++      +K   + +  E+  ++   + ++ +  E+   ++
Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK-MQKQ 476

Query: 250 REDLPHHHHHHHQPEAEPRQ-----EKEEASEREEKEVEQLEHLRDE 291
            E++        Q +  P Q     E+E+  E+EEK  EQ E +RD+
Sbjct: 477 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 523



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 13/179 (7%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEE-----EKEE 183
           ++E   MR  +E   ++EE + E+  K E Q+Q +  Q  +   QE+ +E+     E+EE
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518

Query: 184 RKRGPMETF---EDLW-QRHLENGGDLQKRVAEKASDKETAQFQAEEK-GVRVLGGDRSL 238
           + R   E +   + +W Q  +    D      EK  D+E   +  EE+   +    ++  
Sbjct: 519 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578

Query: 239 WQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
           W   E+   E R  +        + E   R+++E+  E+EEK  EQ E + ++ +K+ E
Sbjct: 579 WDQEEKMREEER--MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQE 635



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 45/171 (26%), Positives = 82/171 (47%), Gaps = 13/171 (7%)

Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE--KEERKRGPMET 191
           KMR  ++   E+EE++ ++  K   QE+ +  +   Q  +  D+EE+  +EER R   + 
Sbjct: 538 KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597

Query: 192 FEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERRE 251
             +  +   E    +Q++  EK  ++E   ++ EEK   +   +  +W+  E+   E+ E
Sbjct: 598 MREEEEMMREQEEKMQEQ-EEKMQEQEEKMWEQEEK---MQEQEEKMWEQEEK-MWEQEE 652

Query: 252 DLPHHHHHHHQPEA----EPRQEKEEASEREEK--EVEQLEHLRDELKKVT 296
            +        Q E     E  QE+E+  E+EEK  E E++E    E +K T
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 38/178 (21%), Positives = 87/178 (48%), Gaps = 14/178 (7%)

Query: 128 KKQEAGKMRSSQEVRDEE------EEEVAERTHKSEVQ--EQAIRMQGHRQLHQEEDEEE 179
           ++QE       +++RD+E      EE + ++T + E +  +Q  +M+   ++ + E +  
Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599

Query: 180 EKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLW 239
           E+EE  R   E  ++  ++  E    + ++  EK  ++E   ++ EEK   +   +  +W
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQ-EEKMQEQEEKMWEQEEK---MWEQEEKMW 655

Query: 240 QGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
           +  ++   E++E L  H     Q + + ++EK    E+ EK+ ++ E    + +K+ E
Sbjct: 656 E--QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 46/203 (22%), Positives = 94/203 (46%), Gaps = 26/203 (12%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAI-------------- 163
           EEK     +  +++  KM   +E   E+EE++ E+  K   QE+ +              
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668

Query: 164 ---RMQGHRQLHQEEDE--EEEKEERKRGPME--TFEDLWQRHLENGGDLQKRVAEKASD 216
              +MQ   ++ ++E++  E+EK E+K    E  T++    R  E+  + +K++ E+   
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728

Query: 217 KETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEA----EPRQEKE 272
               + + +E+  ++   +  +W+  E+   E+ E +        Q E     E  QE+E
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEK-MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 787

Query: 273 EASEREEKEVEQLEHLRDELKKV 295
           +  E+EEK  +Q E +R + +K+
Sbjct: 788 KIWEQEEKMRDQEEKMRGQEEKM 810



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/180 (22%), Positives = 81/180 (45%), Gaps = 32/180 (17%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
           E+K  L    K QE  +    QE +  ++EE+  +  K   QE         ++ ++ED+
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE---------KMREQEDQ 545

Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237
             E+EE+ R   +  + +W        D ++R+ +K  ++E   +  EEK          
Sbjct: 546 MWEQEEKMR---DQEQKMW--------DQEERMEKKTQEQEKKTWDQEEK---------- 584

Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
                E    ER + +        + E + ++++E+  E+EEK  EQ E ++++ +K+ E
Sbjct: 585 --MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE 642



 Score = 36.6 bits (83), Expect = 0.029
 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 9/119 (7%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED- 176
           E+K  L    K QE  K+   +E   ++EE++  +  K   QE+ +R Q  +   QEE  
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831

Query: 177 -EEEEK----EERKRGPMETFEDLWQRHLENGGDLQKRV---AEKASDKETAQFQAEEK 227
             +EEK    EE+  G  E  E+  Q   E   + ++++    EK  ++E      EEK
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890



 Score = 35.8 bits (81), Expect = 0.049
 Identities = 38/189 (20%), Positives = 93/189 (49%), Gaps = 18/189 (9%)

Query: 129 KQEAGKMRSSQEVRDE-----EEEEVAERTHKSEVQEQAIRMQGH-RQLHQE-EDEEEEK 181
           +++  +MR  +++ ++     EE+++ E+  K+  QE+ ++ +   R+  ++  +EEE  
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466

Query: 182 EERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQG 241
            E++    +  E++W++  E     Q+R+ E+  +K   Q + +E+  ++   +  +   
Sbjct: 467 REQEEKMQKQEENMWEQ--EEKEWQQQRLPEQ-KEKLWEQEKMQEQEEKIWEQEEKIRDQ 523

Query: 242 AERGGGE----RREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
            E  G E    R+E +        + E + R ++++  ++EE+    +E    E +K T 
Sbjct: 524 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER----MEKKTQEQEKKTW 579

Query: 298 TLGEQLRRE 306
              E++R E
Sbjct: 580 DQEEKMREE 588


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 55/216 (25%), Positives = 94/216 (43%), Gaps = 16/216 (7%)

Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161
           L KEL        A  EE  L      +Q+  KM   +E   E EE++ E+  K   QE+
Sbjct: 258 LGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE 316

Query: 162 AIRMQGHRQLHQEED---------EEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAE 212
            +R Q      +EE          E+EEK       M   E + ++  +   + + R  E
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376

Query: 213 KASDKETAQFQAEEK---GVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQ 269
           K  ++E   ++ EEK       +     + Q  E   GE+ E +        + E + R+
Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436

Query: 270 EKEEASEREEKEVEQLEHLRDE---LKKVTETLGEQ 302
           ++E+  E+E+K  EQ E +R++   +++  E +GEQ
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 52/187 (27%), Positives = 90/187 (48%), Gaps = 10/187 (5%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--EEEEKEERK 185
           K+QE  K+R  QE R E+E ++  +  K   QE+ IR Q      QEE   E+EEK   +
Sbjct: 365 KRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQ 423

Query: 186 RGPMETFEDLWQRHLENGGDLQKRVAEKAS----DKETAQFQAEEKGVRV--LGGDRSLW 239
              M+  E+  +R  E   + +K++ E+       +E  Q Q E+ G +   +    +  
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483

Query: 240 QGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETL 299
           Q  E     + E +        + E + R+++E   E+EEK  EQ E + ++ +K+ E  
Sbjct: 484 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ- 542

Query: 300 GEQLRRE 306
            E++RR+
Sbjct: 543 EEKMRRQ 549



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 49/177 (27%), Positives = 85/177 (48%), Gaps = 15/177 (8%)

Query: 128 KKQEAGKMRSSQEVRDEEE-----EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE 182
           K  E  K+R  +E R EEE     E+  E+  K   QE+ IR Q  +   QEE  +E++E
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411

Query: 183 ERKRGPMETFEDLWQR--HLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240
             K G  E  E +W++   ++   +  +R  EK  ++E    + EEK    +     + Q
Sbjct: 412 --KMGEQE--EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK----IREQEEMMQ 463

Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
             E   GE+   +        + E + R+++E+  E+E+K  EQ E +R++ + + E
Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 47/189 (24%), Positives = 93/189 (49%), Gaps = 23/189 (12%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
           EEK     +   ++  KMR  +E+  E+EE++ E   K   QE+ IR Q  ++  +E+  
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIR 373

Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237
           E+EK + +   M      W R  E   + ++++ E+   +E  Q Q E+ G +    +  
Sbjct: 374 EQEKRQEQEAKM------W-RQEEKIREQEEKIREQ---EEMMQEQEEKMGEQ----EEK 419

Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
           +W        E+ E++        + E + R+++++  E+EEK  EQ E ++++ +K+ E
Sbjct: 420 MW--------EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGE 471

Query: 298 TLGEQLRRE 306
             G+   +E
Sbjct: 472 QEGKMCEQE 480



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 42/180 (23%), Positives = 85/180 (47%), Gaps = 20/180 (11%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
           EEK     +  +++  KM   +E   E+EEE+ E+  K   QE+ IR Q  +++ ++E++
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ-EKKIREQEEK 454

Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237
             E+EE  +   E   +   +  E    +Q++  E+   ++  + + +EK +R       
Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ--EEKMRRQEEKIREQEKKIR------- 505

Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
                     E+ E +        + E +  +++E+  E+EEK  EQ E +R + +K+ E
Sbjct: 506 ----------EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 39/183 (21%), Positives = 81/183 (44%), Gaps = 19/183 (10%)

Query: 104 KELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAI 163
           +E+   +       EEK     +  +++  KMR  +E   E+E+++ E+  K   QE+ +
Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462

Query: 164 RMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRV---AEKASDKETA 220
           + Q      ++  E+E K   +   M+  E+  +R  E   + +K++    EK  ++E  
Sbjct: 463 QEQ-----EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517

Query: 221 QFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEK 280
             + EEK          +W+  E+   E+ E +        + E + R+++    ++EEK
Sbjct: 518 MQEQEEK----------MWEQEEK-MCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566

Query: 281 EVE 283
             E
Sbjct: 567 MQE 569


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 39/182 (21%), Positives = 91/182 (50%), Gaps = 5/182 (2%)

Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED-EEEEKEERKRGP 188
           ++  +MR  +E   E+EE+V ++  + + QE+ +R Q  +   QEE   E+E++  K+  
Sbjct: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283

Query: 189 METFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGE 248
               E+      E   + ++++ E+       + Q  E+  ++   +  +W+  E+   E
Sbjct: 284 QTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ-MWE 342

Query: 249 RREDLPHHHHHHHQPEAEPRQEKEEASEREE---KEVEQLEHLRDELKKVTETLGEQLRR 305
           ++E +        + E + ++++E+  ++EE   K+ EQ+    ++++K  E +GEQ  +
Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ 402

Query: 306 EG 307
            G
Sbjct: 403 MG 404



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 42/195 (21%), Positives = 90/195 (46%), Gaps = 7/195 (3%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRM----QGHRQLHQ 173
           E+ G      +KQE    +  +++R +EE+   +     E +EQ ++     +   Q  +
Sbjct: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE 293

Query: 174 EEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEE--KGVRV 231
           +E++  E+EE+ R   E   +  ++  E    + K+  +    KE    Q E+  K    
Sbjct: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353

Query: 232 LGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE 291
           +G      Q  E    ++ E +        + E + R+++E+  E++E+  EQ E +R++
Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ 413

Query: 292 LKKVTETLGEQLRRE 306
            +++ E   EQ+R++
Sbjct: 414 EEQMGEQ-KEQMRKQ 427



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 42/178 (23%), Positives = 85/178 (47%), Gaps = 21/178 (11%)

Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEE--EEKEERKRG 187
           ++ G+M   +E   E+EE++ ++  +   QE+ +R Q  +   QEE  +  EE+ +++  
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEE 255

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
            M   E+  +   E     Q R  E+   K+  Q + EE+      G++      E    
Sbjct: 256 QMRKQEEQMREQEE-----QMREQEEQMLKQKEQTEQEEQ-----TGEQ------EEQMR 299

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHL---RDELKKVTETLGEQ 302
           E+ E +        + E + R+++E+  ++EE+  EQ E +   ++++ K  E +GEQ
Sbjct: 300 EQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ 357



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 37/182 (20%), Positives = 86/182 (47%), Gaps = 7/182 (3%)

Query: 125 GDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184
           G  ++QE G++R  +    E+E +V E+  +   QE  +R Q   Q+ ++E +  E+E +
Sbjct: 108 GQVREQE-GQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQ 165

Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAER 244
            R       +   +  E  G ++++  +    +     Q E+     +G      Q  E 
Sbjct: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ-----MGEQEEQMQKQEE 220

Query: 245 GGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLR 304
             GE+ E +        + E + ++++E+  ++EE+  +Q E +R++ +++ E   + L+
Sbjct: 221 QMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280

Query: 305 RE 306
           ++
Sbjct: 281 QK 282



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 43/191 (22%), Positives = 85/191 (44%), Gaps = 16/191 (8%)

Query: 125 GDFKKQEAGKMRSSQEVRDEE----EEEVAERTHKSEVQEQAIRMQGHR-QLHQEEDEEE 179
           G  ++QE        +VR++E    E+E   R  + +V+EQ  +++    Q+ ++E +  
Sbjct: 52  GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111

Query: 180 EKEERKRGPMETFEDLWQRHLENGGDL-----QKRVAEKASDKETAQFQAEEKGVRVLGG 234
           E+E + R       +   +  E  G +     Q R  E    ++  Q + +E  VR   G
Sbjct: 112 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 171

Query: 235 DRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREE---KEVEQLEHLRDE 291
                +G  R   E+   +        + E +  +++E+  E+EE   K+ EQ+    ++
Sbjct: 172 QVREQEGQVR---EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQ 228

Query: 292 LKKVTETLGEQ 302
           ++K  E +GEQ
Sbjct: 229 MRKQEEQMGEQ 239



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 35/164 (21%), Positives = 72/164 (43%), Gaps = 32/164 (19%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHR------QLHQEEDEEEEKE 182
           +++  +MR  +E   E+EE++ E+  +   QE+ +  Q  +      Q+ ++E++  E+E
Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE 358

Query: 183 ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242
           E+ +   E                Q R  E+   K+  Q + +E+ +R            
Sbjct: 359 EQMQKQEE----------------QVRKQEEQMRKQEEQMRKQEEQMR----------KQ 392

Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286
           E   GE++E +        + E +  ++KE+  ++EE   EQ E
Sbjct: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436



 Score = 35.0 bits (79), Expect = 0.084
 Identities = 43/181 (23%), Positives = 78/181 (43%), Gaps = 21/181 (11%)

Query: 128 KKQEAGKMRSSQEVRDEEEE-EVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKR 186
           +K E  K+   QE +  E+E +V E+  +   QE  +R Q   Q+ ++E +  E+E + R
Sbjct: 39  RKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVR 97

Query: 187 GPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG 246
                         E  G  Q R  E    ++  Q + +E  VR   G     +G  R  
Sbjct: 98  --------------EQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-- 139

Query: 247 GERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
            E+   +        + E + R+++ +  E+E +  EQ   +R++  +V E  G+   +E
Sbjct: 140 -EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQE 198

Query: 307 G 307
           G
Sbjct: 199 G 199



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 40/185 (21%), Positives = 77/185 (41%), Gaps = 10/185 (5%)

Query: 126 DFKKQEAGKMRSSQEVRDEEEE---EVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE 182
           + K++ A      Q V  E+ E    + E   K E  +  +  +G  Q+ ++E +  E+E
Sbjct: 8   ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEG--QVREQEGQVREQE 65

Query: 183 ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242
            + R       +   +  E  G  Q R  E    ++  Q + +E  VR   G     +G 
Sbjct: 66  GQVREQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 123

Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302
            R   E+   +        + E + R+++ +  E+E +  EQ   +R++  +V E  G+ 
Sbjct: 124 VR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180

Query: 303 LRREG 307
             +EG
Sbjct: 181 REQEG 185



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 1/55 (1%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE 182
           +KQE  +MR  +E   E++E++ E+  +   QE+ +  Q  +   QEE   E+KE
Sbjct: 383 RKQEE-QMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 3/60 (5%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           +KQE  +MR  +E   ++EE++ E+  K ++ EQ  +M+   +   E+ E+  K+E   G
Sbjct: 376 RKQEE-QMRKQEEQMRKQEEQMGEQ--KEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMG 432



 Score = 29.3 bits (64), Expect = 4.6
 Identities = 39/174 (22%), Positives = 72/174 (41%), Gaps = 14/174 (8%)

Query: 136 RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPME--TFE 193
           R + E   E+  E+ E     E ++  I      QLH +E + + + ++   P E    E
Sbjct: 3   RITNEELKEKNAELQEELQLVETEKSEI------QLHIKELKRKLETDKIPLPQEGQVRE 56

Query: 194 DLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDL 253
              Q   + G   Q R  E    ++  Q + +E  VR   G     +G  R   E+   +
Sbjct: 57  QEGQVREQEG---QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR---EQEGQV 110

Query: 254 PHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307
                   + E + R+++ +  E+E +  EQ   +R++  +V E  G+   +EG
Sbjct: 111 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 164


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 43/168 (25%), Positives = 82/168 (48%), Gaps = 18/168 (10%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           K +E  +MR  ++   EEEE + E+  K + QE+ +R Q  +   QEE  +E++E+    
Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM--- 611

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
             E  E +W++  E          +K  ++E   ++ EEK   +   +  +W+  E+   
Sbjct: 612 -WEQEEKMWEQEEE----------DKMQEQEEMMWEQEEK---MQEQEEKMWEQEEK-MR 656

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKV 295
           E+ E +          E + R+++E+   +EEK  EQ E +R + +K+
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 46/189 (24%), Positives = 91/189 (48%), Gaps = 14/189 (7%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED-EEEEKEERKRG 187
           +++  K+R  +E    +EE + E+  K   QE+ +R Q  R   QE++  E+EKE R++ 
Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASD--KETAQFQAEEKGVR-----VLGGDRSLWQ 240
            +   E+  Q   E   + ++++ E+     ++  +   +EK +R     +   +  +W+
Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 363

Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE---LKKVTE 297
             ER    R ++           + E  QE+E   ERE+K  E+ E +R++   ++K  E
Sbjct: 364 QDER---LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420

Query: 298 TLGEQLRRE 306
            + EQ  +E
Sbjct: 421 NMWEQEEKE 429



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 46/190 (24%), Positives = 88/190 (46%), Gaps = 28/190 (14%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHR------QL 171
           +EK L   + + +E  K+R  +E   E+EE++ E+  K   QE+ +  Q  R      Q+
Sbjct: 288 QEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 347

Query: 172 HQEEDEEEEKEER----------KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQ 221
            ++E +  ++EER          K   M   E +W++  E     ++R+ E+       +
Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ--EEKMQEEERIREREKKMREEE 405

Query: 222 FQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKE 281
               E+  ++   + ++W+  E+   ++R  LP         + E   E+E+  E+EEK 
Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQR--LPE--------QKEKLWEQEKMQEQEEKI 455

Query: 282 VEQLEHLRDE 291
            EQ E +RD+
Sbjct: 456 WEQEEKIRDQ 465



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 45/166 (27%), Positives = 78/166 (46%), Gaps = 18/166 (10%)

Query: 139 QEVRDEEEEEVAERTHKSEVQE----QAIRMQGHRQLHQEEDEEEEKEERKRGPMETFED 194
           QE   E+EE++ E+  K   QE    Q  +M    ++ ++ED+  E+EE+ R   +   D
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 504

Query: 195 LWQRHLENGGDLQKRVAEKASDKETAQFQAEEK---GVRVLGGDRSLWQGAERGGGERRE 251
             +R  E   D + R  E+   ++   +Q EEK     +    ++  W   E+   E R 
Sbjct: 505 QEERMWEQ--DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER- 561

Query: 252 DLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
                     + E + R+E+E   E+EEK  EQ E +R++ +K+ E
Sbjct: 562 --------MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 41/169 (24%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           K QE  K    QE +  EEE + ER  K   +E+ +R        ++E++ +E+EE+ R 
Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR--------EQEEKMQEQEEKMR- 591

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
             E  E +W++             EK  ++E   ++ EEK          +W+  E    
Sbjct: 592 --EQEEKMWEQE------------EKMQEQEEKMWEQEEK----------MWEQEEEDKM 627

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEAS-EREEKEVEQLEHLRDELKKV 295
           + +E++          + E  QE+EE   E+EEK  EQ E +R++ +K+
Sbjct: 628 QEQEEMMWE-------QEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 47/194 (24%), Positives = 91/194 (46%), Gaps = 9/194 (4%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEE-VAERTHKSEVQEQAIRMQGHRQLHQEED 176
           EE+ +   + K +E  +M   QE + +E+EE + E+  K   QE+ ++ Q  +   QEE 
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617

Query: 177 EEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDR 236
             E++EE K    E  E +W++  E   + ++++ E+       + +  E+  ++ G + 
Sbjct: 618 MWEQEEEDKMQEQE--EMMWEQE-EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674

Query: 237 SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQE-----KEEASEREEKEVEQLEHLRDE 291
            + +  E+  G+  +          Q E    QE     +EE    +E+  E+ E +RD+
Sbjct: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734

Query: 292 LKKVTETLGEQLRR 305
            +K+ E L E   R
Sbjct: 735 KEKMQERLPEHEER 748



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 38/176 (21%), Positives = 82/176 (46%), Gaps = 9/176 (5%)

Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPM 189
           ++  KMR  ++   ++EE + E+  +   +E+ +R Q  +   QEE   EEK+ +++   
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQQEEKMREEKKTQEQEKK 548

Query: 190 ETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGER 249
              ++   R  E   + +K++ E+       + + +E+  ++   +  +W+  E+   + 
Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608

Query: 250 REDLPHHHHHHHQPEAEPRQEKEE--------ASEREEKEVEQLEHLRDELKKVTE 297
            +          Q E +  QE+EE          E+EEK  EQ E +R++ +K+ E
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 36/181 (19%), Positives = 88/181 (48%), Gaps = 8/181 (4%)

Query: 126 DFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE--- 182
           +  +++  KM+  +E   E+EE++ E+  K + QE+ +  Q  +   QEE+++ +++   
Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633

Query: 183 --ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240
             E++    E  E +W++  E   + ++++ E+    +  + +  E+  ++ G +  + +
Sbjct: 634 MWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692

Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300
             E+  G+  E+           + E    +EE  E+EE+  +Q E +++ L +  E   
Sbjct: 693 QEEKMRGQ--EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCS 750

Query: 301 E 301
           E
Sbjct: 751 E 751



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 40/161 (24%), Positives = 75/161 (46%), Gaps = 16/161 (9%)

Query: 139 QEVRDEEEEEVAERTHKSEVQEQAIRMQGH-RQLHQEEDEEEEKEERKRGPMETFEDLWQ 197
           QE +  EE++  E+  K+  QE+ +R +   R+  ++  EEEE    +   M+  E+  +
Sbjct: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591

Query: 198 RHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHH 257
              E   + +    EK  ++E   ++ EEK          +W+  E    + +E++    
Sbjct: 592 EQEEKMWEQE----EKMQEQEEKMWEQEEK----------MWEQEEEDKMQEQEEMMWEQ 637

Query: 258 HHHHQPEAEPRQEKEE-ASEREEKEVEQLEHLRDELKKVTE 297
               Q + E   E+EE   E+EEK  EQ E ++ + +K+ E
Sbjct: 638 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRE 678



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 14/159 (8%)

Query: 139 QEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQR 198
           QE    +EEE+ E+  K   QE+ +  Q  R L ++E +  E+EE+ R   +   +  + 
Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEER-LREQEGKMREQEEKMRRQEKRLREQEKE 291

Query: 199 HLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHH 258
             E   +L+++  +K  ++E    + EEK          +W+  E+   E+ E +     
Sbjct: 292 LREQEKELREQ--KKLREQEEQMQEQEEK----------MWEQEEK-MREQEEKMWRQEE 338

Query: 259 HHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
              + E + R+++++  ++EE+  EQ E LR++ +++ E
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 377



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 21/150 (14%)

Query: 127 FKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKR 186
           ++++E  KM+  +E+  E+EE++ E+  K   QE+ +R        ++E++  E+EE+ +
Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR--------EQEEKMREQEEKMQ 670

Query: 187 GPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG 246
           G  E   +  +  ++   +  +   EK   +E   +  EEK   + G +  +W   E   
Sbjct: 671 GQEEKMRE-QEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK---MWGQEEKMWGQEEMRE 726

Query: 247 GERR---------EDLPHHHHHHHQPEAEP 267
            E R         E LP H     +P   P
Sbjct: 727 KEERIRDQKEKMQERLPEHEERCSEPCLPP 756


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 44/174 (25%), Positives = 85/174 (48%), Gaps = 17/174 (9%)

Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE---ERKR 186
           +E  +MR  ++   EEEE + E+  K + QE+ +R Q  +   QEE  +E++E   E++ 
Sbjct: 2   REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61

Query: 187 GPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG 246
              E  E +W+         Q+R+ E+         +  EK  R+   ++ +WQ  E+  
Sbjct: 62  KMWEQEEKMWE---------QQRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMR 110

Query: 247 GERR---EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
            +++   E +        + E    +++E+  E+EEK  EQ E +R++ +K+ E
Sbjct: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 48/185 (25%), Positives = 90/185 (48%), Gaps = 21/185 (11%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEE-VAERTHKSEVQEQAIRMQGHRQLHQEE- 175
           EE+ +   + K +E  +M   QE + +E+EE + E+  K   QE+ ++ Q  +   QEE 
Sbjct: 3   EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62

Query: 176 --DEEEEKEERKRGPMETFEDLWQ-----RHLENGGDLQK---RVAEKASDKETAQFQAE 225
             ++EE+  E++R P E  E +W+     R  E     QK   +V +    K+T + + +
Sbjct: 63  MWEQEEKMWEQQRLP-EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121

Query: 226 EKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQL 285
           E+  ++   +  +W        E+ E +        + E + R+++E+  E+EEK   Q 
Sbjct: 122 EQEEKMQEQEEMMW--------EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173

Query: 286 EHLRD 290
           E +RD
Sbjct: 174 EKMRD 178



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 39/158 (24%), Positives = 74/158 (46%), Gaps = 37/158 (23%)

Query: 145 EEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGG 204
           EEE + ER  K   +E+ +R        ++E++ +E+EE+ R   E  E +W++      
Sbjct: 3   EEERMREREKKMREEEEMMR--------EQEEKMQEQEEKMR---EQEEKMWEQE----- 46

Query: 205 DLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPE 264
                  EK  ++E   ++ EEK          +W+  E+   ++R  LP       + +
Sbjct: 47  -------EKMQEQEEKMWEQEEK----------MWEQEEKMWEQQR--LPEQKEKMWEQD 87

Query: 265 AEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302
              R+++E    RE+K  +Q+E +R++ K   E + EQ
Sbjct: 88  ERLREKEERM--REQKMWQQVEKMREKKKTQEEKMQEQ 123



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 1/68 (1%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           KK +  KM+  +E   E+EE + E+  K + QE+ +  Q  +   QEE   E+ EE+ +G
Sbjct: 113 KKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ-EEKMQG 171

Query: 188 PMETFEDL 195
             E   D+
Sbjct: 172 QEEKMRDV 179



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 1/60 (1%)

Query: 117 TEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEE-VAERTHKSEVQEQAIRMQGHRQLHQEE 175
           T+E+ +   + K QE  +M   QE + +E+EE + E+  K   QE+ +R Q  +   QEE
Sbjct: 115 TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 45/180 (25%), Positives = 89/180 (49%), Gaps = 14/180 (7%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           K+QE  K+R  QE R E+E ++  +  K   QE+ IR Q  +   QEE   E+++ R+  
Sbjct: 459 KRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE 517

Query: 188 PMETFEDLWQ-----RHLENGGDLQKRV---AEKASDKETAQFQAEEK----GVRVLGGD 235
             +  E++W+     R  E     ++++    EK   +E   ++ EEK      ++   +
Sbjct: 518 KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577

Query: 236 RSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKV 295
             +W+  E+   E+ E +        + E   ++++E+  E+EEK  EQ E ++++ +K+
Sbjct: 578 EKVWRQEEK-IREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 39/170 (22%), Positives = 87/170 (51%), Gaps = 18/170 (10%)

Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFE 193
           KM   +++R++EE+    R  + +++EQ  R +   ++ ++E++  E+EE+ R   E  E
Sbjct: 446 KMHEQEKIREQEEK----RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR---EQEE 498

Query: 194 DLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGE----- 248
            +W++  E     Q+++ E+   +E  +   +E+ +R       +W+  E+   +     
Sbjct: 499 KMWRQ--EEKIHEQEKIREEEKRQEQEEMWRQEEKIR---EQEEIWRQKEKIHEQEEKIR 553

Query: 249 -RREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
            + E +       H  E + R+++E+   +EEK  EQ E +R++ +K+ E
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 52/203 (25%), Positives = 92/203 (45%), Gaps = 24/203 (11%)

Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161
           L KEL        A  EE  L      +Q+  KM   +E   E EE++ E+  K   QE+
Sbjct: 331 LGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 389

Query: 162 AIRMQGHRQLHQEED--EEEEKEERKRGPMETFED--------LWQRHLENGGDLQKRVA 211
            IR Q  +   QEE   E+EEK  R+   M   E+        +W++  E   +L++++ 
Sbjct: 390 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKIRELEEKMH 448

Query: 212 EKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEK 271
           E+   +E  + + EE+ +R            E+   + +E          + + E  +E+
Sbjct: 449 EQEKIREQEEKRQEEEKIR------------EQEKRQEQEAKMWRQEEKIREQEEKIREQ 496

Query: 272 EEASEREEKEVEQLEHLRDELKK 294
           EE   R+E+++ + E +R+E K+
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKR 519



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 44/170 (25%), Positives = 80/170 (47%), Gaps = 21/170 (12%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           K+QE  +M   QE +  E+EE+  +  K   QE+ IR Q  +   QEE   +++E+ +  
Sbjct: 518 KRQEQEEMWR-QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR-- 574

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
             E  E +W++             EK  ++E    + EEK    +     + Q  E   G
Sbjct: 575 --EQEEKVWRQE------------EKIREQEEKIREQEEK----IREQEEMTQEQEEKMG 616

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
           E+ E +        + E + R+++E+  E+E+K  EQ E +R++ + + E
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 36/158 (22%), Positives = 71/158 (44%), Gaps = 26/158 (16%)

Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFE 193
           K+R  +E   E+EE++ E+   ++ QE+ +  Q  +   QEE  +E++E+ +R   +  E
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645

Query: 194 DLWQRHLENGGDLQKRV---AEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250
                        +K++    EK  ++E    + EEK          +W+  E+   E+ 
Sbjct: 646 Q------------EKKIREQEEKIREQEEMMQEQEEK----------MWEQEEK-MCEQE 682

Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHL 288
           E +        + E +  +++    ++EEK  E  EHL
Sbjct: 683 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 32/133 (24%), Positives = 63/133 (47%), Gaps = 10/133 (7%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--EEEEKEERKR 186
           +++  K+R  +E+  E+EE++ E+  K   QE+ ++ Q  +   QEE   E+E+K   + 
Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654

Query: 187 GPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG 246
             +   E++ Q   E   + +    EK  ++E    + EEK  R    +  +W+   R  
Sbjct: 655 EKIREQEEMMQEQEEKMWEQE----EKMCEQEEKMQEQEEKMRR---QEEKMWEQEVR-L 706

Query: 247 GERREDLPHHHHH 259
            ++ E +  H  H
Sbjct: 707 RQQEEKMQEHQEH 719



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 13/119 (10%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
           EEK     +  +++  KM   +E   E+EE++ E+  K   QE+ IR Q  +   QEE  
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657

Query: 178 EEEKEERKRGPMETFEDLWQRH---------LENGGDLQKRVAEKASDKETAQFQAEEK 227
            E++E  +    E  E +W++          ++   +  +R  EK  ++E    Q EEK
Sbjct: 658 REQEEMMQ----EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 23/100 (23%), Positives = 50/100 (50%), Gaps = 3/100 (3%)

Query: 104 KELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAI 163
           +E+   +       EEK     +  +++  KMR  +E   E+E+++ E+  K   QE+ +
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664

Query: 164 RMQGHRQLHQEE---DEEEEKEERKRGPMETFEDLWQRHL 200
           + Q  +   QEE   ++EE+ +E++       E +W++ +
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704



 Score = 33.5 bits (75), Expect = 0.24
 Identities = 22/74 (29%), Positives = 43/74 (58%), Gaps = 4/74 (5%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQ-LHQEEDEEEEKEERKRG 187
           +++  K+R  +E+  E+EE++ E+  K   QE+  +MQ   + + ++E++  E+E R R 
Sbjct: 651 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE--KMQEQEEKMRRQEEKMWEQEVRLRQ 708

Query: 188 PMETFEDLWQRHLE 201
             E  ++  Q HLE
Sbjct: 709 QEEKMQE-HQEHLE 721



 Score = 32.3 bits (72), Expect = 0.54
 Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 7/73 (9%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRD-EEEEEVAERTHKSEVQEQAIRMQGHR------Q 170
           +EK +   + K +E  +M   QE +  E+EE++ E+  K + QE+ +R Q  +      +
Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 705

Query: 171 LHQEEDEEEEKEE 183
           L Q+E++ +E +E
Sbjct: 706 LRQQEEKMQEHQE 718



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 37/164 (22%), Positives = 73/164 (44%), Gaps = 18/164 (10%)

Query: 160 EQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLW--QRHLENGGDLQKRVAEKASDK 217
           EQA+     ++   +   EE  +ER    +E + +    +   E    LQ+++    S+K
Sbjct: 239 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK 298

Query: 218 ETAQFQAEE-----KGVRVLGGDRSLWQGAERGGGERR----------EDLPHHHHHHHQ 262
              Q   +E     +  ++L   + L   A+  G E +          E+    +  + Q
Sbjct: 299 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 358

Query: 263 PEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
            E +  +++E+  E EEK  EQ E +R++ +K+ E   E++RR+
Sbjct: 359 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ-EEKMRRQ 401



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 37/152 (24%), Positives = 68/152 (44%), Gaps = 17/152 (11%)

Query: 157 EVQEQAIRMQGHRQLHQEEDEEEEK--EERKRGPMETFEDLWQRHLENGGDLQKRVAEKA 214
           E++E+  ++Q   QL + E  E +   +E KR        L Q+ L+   D   +  +  
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338

Query: 215 SDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEA 274
           S K  AQ +  E           LW    R   ++ E +        + E + ++++E+ 
Sbjct: 339 SAKLQAQVEENE-----------LWN---RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384

Query: 275 SEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
            E+EEK  EQ E +R + + + E   E++RR+
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEK-EEKMRRQ 415


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 44/172 (25%), Positives = 85/172 (49%), Gaps = 16/172 (9%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           K+QE  K+R  QE R E+E ++  +  K   QE+ IR Q  +   QEE   E+++ R+  
Sbjct: 398 KRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEE--KGVRVLGGDRSLWQGAERG 245
             +  E++W            R  EK  ++E    Q E+  +  ++   +  +W+  E+ 
Sbjct: 457 KRQEQEEMW------------RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK- 503

Query: 246 GGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
             ++ E +        + E + R+++E+  E+EEK  EQ E ++++ +K+ E
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 62/233 (26%), Positives = 98/233 (42%), Gaps = 34/233 (14%)

Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161
           L KEL        A  EE  L      +Q+  KM   +E   E EE++ E+  K   QE+
Sbjct: 270 LGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328

Query: 162 AIRMQGHRQLHQEED--EEEEKEER-------KRGPMETFEDLWQRHLENGGDLQKRVAE 212
            IR Q  +   QEE   E+EEK  R       K   M   E++     E   +L++++ E
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE 388

Query: 213 KASDKETAQFQAEEKGVRV----LGGDRSLWQGAERGGGERREDLPHH-----------H 257
           +   +E  + + EE+ +R        +  +W+  E+   E+ E +              H
Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQEKKMWRQEEKIH 447

Query: 258 HHHHQPEAEPRQEKEEASEREEKEVEQLE--------HLRDELKKVTETLGEQ 302
                 E E RQE+EE   +EEK  EQ E        H +++++K  E +  Q
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 43/176 (24%), Positives = 87/176 (49%), Gaps = 22/176 (12%)

Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--EEEEKEERKRGPMET 191
           KM   +++R ++EE+V  +  K   QE+ IR Q  +   QEE   E+EEK   +   +  
Sbjct: 483 KMHEQEKIR-KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541

Query: 192 FEDLWQRHLENGGDLQKRVAEKAS-DKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250
            E++ Q   E  G+ ++++ E+    ++  + + +E+ +R                 E++
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIR-----------------EQK 584

Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
           E +        + E + R+++E   E+EEK  EQ E + ++ +K+ E   E++RR+
Sbjct: 585 EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ-EEKMRRQ 639



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 45/173 (26%), Positives = 89/173 (51%), Gaps = 12/173 (6%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEE--RK 185
           ++QEA   R  +++R E+EE++ E+  K   QE+ I  Q   +  +EE++ +E+EE  R+
Sbjct: 412 QEQEAKMWRQEEKIR-EQEEKIREQEKKMWRQEEKIHEQ---EKIREEEKRQEQEEMWRQ 467

Query: 186 RGPMETFEDLW-QRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAER 244
              +   E++W Q+   +  +  ++  EK   +E      EEK   +   +  +W+  E+
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK---IREQEEKMWRQEEK 524

Query: 245 GGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
              E+ E +        + E   ++++E+  E+EEK  EQ E +R + +K+ E
Sbjct: 525 -IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIRE 575



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 39/160 (24%), Positives = 74/160 (46%), Gaps = 28/160 (17%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGP 188
           +++  K+R  +E+  E+EE++ E+  K + QE+ +R Q  +   QEE   E+KE+ +   
Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-MRRQEEKIREQEEKIREQKEKIR--- 588

Query: 189 METFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGE 248
            E  E +W++             EK  ++E    + EEK          +W+  E+   E
Sbjct: 589 -EQEEKIWEQE------------EKIREQEEMMQEQEEK----------MWEQEEK-MCE 624

Query: 249 RREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHL 288
           + E +        + E +  +++    ++EEK  E  EHL
Sbjct: 625 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 47/192 (24%), Positives = 89/192 (46%), Gaps = 20/192 (10%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
           EEK     +   ++  KMR  +E+  E+EE++ E   K   QE+ IR Q  ++  +E+  
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIR 406

Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRV---AEKASDKETAQFQAEEKGVRVLGG 234
           E+EK + +   M   E+  +   E   + +K++    EK  ++E  + + EEK       
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE--KIREEEKRQE---- 460

Query: 235 DRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294
              +W+  E+     +E++       H        E+E+  ++EEK   Q E + D+ +K
Sbjct: 461 QEEMWRQEEKI--REQEEIWRQKEKMH--------EQEKIRKQEEKVWRQEEKMHDQEEK 510

Query: 295 VTETLGEQLRRE 306
           + E   +  R+E
Sbjct: 511 IREQEEKMWRQE 522



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 35/102 (34%), Positives = 48/102 (47%), Gaps = 6/102 (5%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE--DEEEEKEERK 185
           K QE  KMR  +E   E+EE++ E+  K   QE+ I  Q  +   QEE   E+EEK   +
Sbjct: 559 KMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618

Query: 186 RGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEK 227
              M   E+  Q   E      +R  EK  ++E    Q EEK
Sbjct: 619 EEKMCEQEEKMQEQEEK----MRRQEEKMWEQEVRLRQQEEK 656



 Score = 32.7 bits (73), Expect = 0.41
 Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%)

Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQ-LHQEEDEEEEKEERKRGP 188
           ++  K+R  +E+  E+EE++ E+  K   QE+  +MQ   + + ++E++  E+E R R  
Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE--KMQEQEEKMRRQEEKMWEQEVRLRQQ 653

Query: 189 METFEDLWQRHLE 201
            E  ++  Q HLE
Sbjct: 654 EEKMQE-HQEHLE 665



 Score = 31.6 bits (70), Expect = 0.92
 Identities = 20/65 (30%), Positives = 33/65 (50%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
           EEK     +  +++  KM   +E   E+EE++ E+  K   QE+ +  Q  R   QEE  
Sbjct: 598 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657

Query: 178 EEEKE 182
           +E +E
Sbjct: 658 QEHQE 662



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 19/63 (30%), Positives = 36/63 (57%), Gaps = 7/63 (11%)

Query: 128 KKQEAGKMRSSQEVRD-EEEEEVAERTHKSEVQEQAIRMQGHR------QLHQEEDEEEE 180
           K +E  +M   QE +  E+EE++ E+  K + QE+ +R Q  +      +L Q+E++ +E
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659

Query: 181 KEE 183
            +E
Sbjct: 660 HQE 662



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 37/164 (22%), Positives = 73/164 (44%), Gaps = 18/164 (10%)

Query: 160 EQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLW--QRHLENGGDLQKRVAEKASDK 217
           EQA+     ++   +   EE  +ER    +E + +    +   E    LQ+++    S+K
Sbjct: 178 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK 237

Query: 218 ETAQFQAEE-----KGVRVLGGDRSLWQGAERGGGERR----------EDLPHHHHHHHQ 262
              Q   +E     +  ++L   + L   A+  G E +          E+    +  + Q
Sbjct: 238 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 297

Query: 263 PEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
            E +  +++E+  E EEK  EQ E +R++ +K+ E   E++RR+
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ-EEKMRRQ 340


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 55/211 (26%), Positives = 94/211 (44%), Gaps = 29/211 (13%)

Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161
           L KEL        A  EE  L      +Q+  KM   +E   E EE++ E+  K   QE+
Sbjct: 270 LGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328

Query: 162 AIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQ 221
            IR Q  +   QEE   E++E+ +R      E +W++             EK   +E   
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQE----EMMWEKE------------EKMRRQEEMM 372

Query: 222 FQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKE 281
           ++ EEK  R    +  +W+  E+    R  +   H     + + E RQE+E+  E+E+++
Sbjct: 373 WEKEEKMRR---QEEMMWEKEEK---IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 426

Query: 282 VE------QLEHLRDELKKVTETLGEQLRRE 306
            +      Q E +R++ +K+ E   +  R+E
Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 52/196 (26%), Positives = 95/196 (48%), Gaps = 22/196 (11%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE---DEEEEKEER 184
           K+QE  K+R  QE R E+E ++  +  K   QE+ IR Q  +   QEE   ++E+ +EE 
Sbjct: 412 KRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470

Query: 185 KRGPMETF----------EDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGG 234
           KR   E            E++W R  E   + ++++ ++       + +  E+  ++   
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIW-RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529

Query: 235 DRSLWQGAERGGGERREDLPHHHHHHHQP---EAEPRQEKEEASEREEKEV-EQLEHLRD 290
           +  +W+  E+   E+ E        H Q    E E RQE+E+   R+E+++ EQ E +  
Sbjct: 530 EEKMWRQEEK-IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR 588

Query: 291 ELKKVTETLGEQLRRE 306
           + +K+ E   E+ R+E
Sbjct: 589 QEEKIREQ--EEKRQE 602



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 44/181 (24%), Positives = 87/181 (48%), Gaps = 22/181 (12%)

Query: 128 KKQEAGKMRSSQEVRDEEE------EEVAERTHKSEVQEQAIRMQGHRQLHQEE--DEEE 179
           ++QE    R  +++R++EE      E++ E+  K + QE+ +  Q  +   QEE   E+E
Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625

Query: 180 EKEERKRGPMETFEDLWQRHLENGGDLQKRVA---EKASDKETAQFQAEEKGVRVLGGDR 236
           EK   +   +   E++ Q   E  G+ ++++    EK  ++E   ++ EEK         
Sbjct: 626 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK--------- 676

Query: 237 SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVT 296
              +  E+   E+ E +        + E +  +++E+  E+EEK  EQ E +R + +K+ 
Sbjct: 677 --IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734

Query: 297 E 297
           E
Sbjct: 735 E 735



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 45/188 (23%), Positives = 91/188 (48%), Gaps = 12/188 (6%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
           E++ +   + K  E  ++   +E   E+EE++ ++  K   QE+ IR Q      ++  E
Sbjct: 474 EQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQ-----EEKIRE 528

Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237
           +EEK  R+   +   E++W+   +     +    EK  ++E   ++ EEK   +   +  
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK---IREQEEK 585

Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE---LKK 294
           +W+  E+   E+ E          + E + R+++E+  E+EEK  EQ E +R++    ++
Sbjct: 586 VWRQEEK-IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQE 644

Query: 295 VTETLGEQ 302
             E +GEQ
Sbjct: 645 QEEKMGEQ 652



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 30/185 (16%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE-- 175
           EEK     + ++++  KM   +E   E+EE++ E+  K   QE+ IR Q      QEE  
Sbjct: 590 EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649

Query: 176 DEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRV---AEKASDKETAQFQAEEKGVRVL 232
            E+EEK   +   M+  E+   R  E   + +K++    EK  ++E    + EEK     
Sbjct: 650 GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK----- 704

Query: 233 GGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDEL 292
                +W+  E+                 + E + ++++E+   +EEK  EQ   LR + 
Sbjct: 705 -----MWEQEEK---------------MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744

Query: 293 KKVTE 297
           +K+ E
Sbjct: 745 EKMQE 749



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 45/190 (23%), Positives = 93/190 (48%), Gaps = 14/190 (7%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEE---EEVAERTHKSEVQEQAIRMQGHRQLHQE 174
           EEK     +   ++  K+R  +E   E+E   E+  +R  + +++EQ  R +   ++ ++
Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435

Query: 175 EDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGG 234
           E++  E+EE+ R   E  + +W R  E   + +K   E+   ++   ++ EEK    +  
Sbjct: 436 EEKIREQEEKIR---EQEKKMW-RQEEKIHEQEKIREEEKRQEQEEMWRQEEK----IHE 487

Query: 235 DRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLR--DEL 292
              +W+  E+   E+ E +        + E + R+++E+  E+EEK   Q E +R  +E+
Sbjct: 488 QEEIWRQKEK-MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546

Query: 293 KKVTETLGEQ 302
            +  E + EQ
Sbjct: 547 WREEEKMHEQ 556



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 40/172 (23%), Positives = 83/172 (48%), Gaps = 8/172 (4%)

Query: 139 QEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEE--RKRGPMETFEDLW 196
           +E R E+E+++  +  K   QE+ +  Q  +   QEE  +E++E+  ++   +   E+  
Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621

Query: 197 QRHLENGGDLQKRVAEKASDKETAQFQAEEKGVR--VLGGDRSLWQGAERGGGERREDLP 254
           Q   E   + ++++ E+   +E  Q Q E+ G +   +       Q  E     + E + 
Sbjct: 622 QEQEEKIREQEEKIREQ---EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678

Query: 255 HHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
                  + E + R+++E   E+EEK  EQ E + ++ +K+ E   E++RR+
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ-EEKMRRQ 729



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 37/168 (22%), Positives = 77/168 (45%), Gaps = 4/168 (2%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGP 188
           +++  KMR  +E+  E+EE++  +      +E+ +R Q    + ++E++   +EE     
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKMRRQEEMMWEK 389

Query: 189 METFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGE 248
            E   +L ++  E     ++    +  +K   Q + +E+  ++   +  + +  E+   +
Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449

Query: 249 RREDLPHHHHHHHQP---EAEPRQEKEEASEREEKEVEQLEHLRDELK 293
            ++        H Q    E E RQE+EE   +EEK  EQ E  R + K
Sbjct: 450 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 10/100 (10%)

Query: 104 KELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAI 163
           +E  G +       EEK       ++QE    R  +++R E+E+++ E+  K   QE+ +
Sbjct: 646 EEKMGEQEEKMCEQEEK------MQEQEETMWRQEEKIR-EQEKKIREQEEKIREQEEMM 698

Query: 164 RMQGHRQLHQEEDEEEEKE---ERKRGPMETFEDLWQRHL 200
           + Q  +   QEE   E++E   E++       E +W++ +
Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 55/195 (28%), Positives = 93/195 (47%), Gaps = 15/195 (7%)

Query: 118  EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTH----KSEVQEQAIRMQGHRQLHQ 173
            EE+  L  D +++ + + R  Q+ R + EEE   R H    K  +QEQ   ++  +QL Q
Sbjct: 851  EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ---LRKEQQLLQ 907

Query: 174  EEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLG 233
            EE+EE ++EER++   +  E  ++   +   + ++ + E   ++E  + Q  E+  R   
Sbjct: 908  EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE---EREKRRRQERERQYR--- 961

Query: 234  GDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELK 293
             D+ L Q  E+  GE  E            E E  Q++EE   REE+E  + +    + +
Sbjct: 962  KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021

Query: 294  KVTETL--GEQLRRE 306
            K  E     EQL RE
Sbjct: 1022 KKDELQQEEEQLLRE 1036



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 48/203 (23%), Positives = 88/203 (43%), Gaps = 29/203 (14%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRM--QGHRQLHQEEDEEEEKEERKR 186
           K E  + R  Q++R E++E   +R  + E +E+  +   + H +  +E++  EE++E+ R
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694

Query: 187 GPMETFEDLWQRHLENGGDL-QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245
             +++    WQ  LE+  D  Q +V  +   +E  + + E++  R        WQ  ER 
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754

Query: 246 GGERREDL--------------------------PHHHHHHHQPEAEPRQEKEEASEREE 279
             +++E+                           P       Q  AE RQ++E+    EE
Sbjct: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEE 814

Query: 280 KEVEQLEHLRDELKKVTETLGEQ 302
           +E EQ    R E +K  + L E+
Sbjct: 815 EEKEQRRRQRREREKELQFLEEE 837



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 11/171 (6%)

Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAI-RMQGHRQLHQEEDEEEEKEERKRGPMETF 192
           ++R  Q++R E+EEE  E+ H+ E +EQ + R Q  R+   + +EE E+ E++R   +  
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477

Query: 193 EDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERRED 252
            D  +   E    L++    +  ++   Q + E++  R     R           E  E 
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ----------EEEER 527

Query: 253 LPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQL 303
           L        Q   E  + +E+  +REE++  + E     LK+  E   +QL
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 43/180 (23%), Positives = 84/180 (46%), Gaps = 21/180 (11%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAE--------RTHKSEVQEQAIRMQGHRQLHQEEDEE-- 178
           ++E  + R  +  R EEEE + +        R  + E +EQ ++ +  ++L QE  E+  
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567

Query: 179 -EEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237
             E+EER+   ++  E+  Q+ L+   + ++R+ ++   +E  + + EE+        R 
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKR--EQEERLEQRLKREEVERLEQEER--------RE 617

Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
                E    ERR+ L        + + + R+E++E  E+  K  E+ E L   LK+  E
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 48/187 (25%), Positives = 93/187 (49%), Gaps = 15/187 (8%)

Query: 125 GDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG-HRQLHQEEDEEE---- 179
           G  +KQ+  + R  +  ++EEE+E  +R      +E+ ++ +   RQ   +E+EE+    
Sbjct: 222 GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281

Query: 180 EKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLW 239
           E++E +R   E  E+  Q+ L     L+++  E+  +++  + + +E+  +    +    
Sbjct: 282 ERQELRRERQE--EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ---QEERRE 336

Query: 240 QGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETL 299
           Q   R   ERRE          + E + R+E+EE  ER E+++ + + LR E +   E  
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEE--ERREQQLRREQQLRREQQLRRE-- 392

Query: 300 GEQLRRE 306
            +QLRRE
Sbjct: 393 -QQLRRE 398



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 6/183 (3%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHR---QLHQEEDEEEEKEER 184
           ++Q+  ++R  Q++R ++EEE  E+  +   Q++    Q  R   QL +E++E  E++ R
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR 352

Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAER 244
           +    E  E   +R  E     Q+   E+   +E  Q    E+ +R     R   Q    
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRRE 410

Query: 245 GGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTET-LGEQL 303
               R + L        + E E  ++K E   RE++   + E  RD LK+  ET   EQ 
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470

Query: 304 RRE 306
           RR+
Sbjct: 471 RRK 473



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 52/212 (24%), Positives = 87/212 (41%), Gaps = 28/212 (13%)

Query: 123  LLGDFKKQEAGKMRSSQEVRDEE--EEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEE-- 178
            LLG+ ++++  + R   + RD    EEE  ER  + E + +  + Q  +QL +EE EE  
Sbjct: 1270 LLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKR 1329

Query: 179  -------------------EEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKET 219
                               EE+  R++     F +   RH E G    +        +  
Sbjct: 1330 RRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE 1389

Query: 220  AQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEP---RQEKEEASE 276
             +F  EE+ +R    ++ L Q  +R   E  + L          E E    RQE+E    
Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449

Query: 277  REEKEVEQLEH--LRDELKKVTETLGEQLRRE 306
             EE+++ Q  H   R+E + + E   +QL R+
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 56/211 (26%), Positives = 91/211 (43%), Gaps = 27/211 (12%)

Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167
           G +    A  + K  LL D ++QE  + R     R  EEE    R  K + QE+ +    
Sbjct: 94  GLDEEKRARCDGKESLLQD-RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL---- 148

Query: 168 HRQLHQEEDEEEEKEER--KRGPMETFEDLWQRHLENGGDLQKRVAEK----ASDKETAQ 221
                 E +E+ EK+ER  +R      E+LW++  E     ++R  E+        ET +
Sbjct: 149 -----AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE 203

Query: 222 FQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKE 281
           F  EE+  R     R L +   +G  E+++          Q E E    K E   R+E+E
Sbjct: 204 FPDEEQLRR-----RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258

Query: 282 VEQLE------HLRDELKKVTETLGEQLRRE 306
             Q E       L++E +++ +   ++LRRE
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRE 289



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 22/196 (11%)

Query: 128  KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE---------- 177
            +++   + R  ++++ +EE+ + E   K   QE+  + +   +L QEE++          
Sbjct: 953  RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012

Query: 178  --EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGD 235
              E E++ RK+  ++  E+   R       LQ+R   +   +E  + Q EE+  ++LG +
Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQER---ERQYREEEELQQEEE--QLLGEE 1067

Query: 236  RSLWQGAERGGGERREDLPHHHHH---HHQPEAEPRQEKE-EASEREEKEVEQLEHLRDE 291
            R   +  E     R+E+            +PE   RQE+E +  E EE + E+ + LR+E
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127

Query: 292  L-KKVTETLGEQLRRE 306
              K+  + L  Q R E
Sbjct: 1128 REKRRRQELERQYREE 1143



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 45/184 (24%), Positives = 82/184 (44%), Gaps = 15/184 (8%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKS--------EVQEQAIRMQGHRQLHQEEDEEEE 180
           + E  + R  + + +EEE+E   R  +         E +EQ  R +  +QL +EED  +E
Sbjct: 799 RAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE 858

Query: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240
            +ER+R   +  +  W+  LE   + +KR       K   Q Q   K  ++L  +    Q
Sbjct: 859 DQERRRSQEQRRDQKWRWQLE---EERKRRRHTLYAKPALQEQL-RKEQQLLQEEEEELQ 914

Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE--LKKVTET 298
             ER    RR++    +    Q + E  Q   E  E+  ++  + ++ +D+   +K  + 
Sbjct: 915 REER-EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973

Query: 299 LGEQ 302
           LGE+
Sbjct: 974 LGEE 977



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 54/206 (26%), Positives = 88/206 (42%), Gaps = 32/206 (15%)

Query: 118  EEKGLLLGDFKKQEAGKM----RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQ 173
            EE+ LL  + +K+   ++    R  +EV+ EEE+ + E   K   QE   + +   +L Q
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178

Query: 174  EED----EEEEK--EERKRGPMETFEDLWQRHLENGGDLQKRVAEK-------------- 213
            EE+    EE+EK  +ER+R   E  E   Q+  +   D  +R   K              
Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238

Query: 214  ---ASDKETAQF-QAEEKGVRVLGGDRS----LWQGAERGGGERREDLPHHHHHHHQPEA 265
                  +E  QF Q E+  +R     +     L +  ER   + R        H  + E 
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298

Query: 266  EPRQEKEEASEREEKEVEQLEHLRDE 291
              R+E++EA  R+ K  E+ + LR+E
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREE 1324



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 34/164 (20%), Positives = 84/164 (51%), Gaps = 8/164 (4%)

Query: 128  KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
            +++   ++R  ++ +  EEE++ +     E +EQ +R Q   +  +EE+++  ++ER+R 
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQ-----EGEEQQLRRQERDRKFREEEQQLRRQERERK 1708

Query: 188  PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
             ++  + L ++ LE     ++++ +   + E  Q + +E+  ++L  ++   +  E+   
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQ---ETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765

Query: 248  ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE 291
             +  D         + E E +Q + + S+R+ +E EQL   R+E
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 51/199 (25%), Positives = 98/199 (49%), Gaps = 20/199 (10%)

Query: 119 EKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEE 178
           E+ L L + +++E  + R  Q++R E+EE   +R  + E +E   R+Q  ++L  E+   
Sbjct: 486 ERWLKLEEEERREQQERRE-QQLRREQEERREQRLKRQEEEE---RLQ--QRLRSEQQLR 539

Query: 179 EEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS- 237
            E+EER+   ++  E   ++ LE     Q+   E+   ++    + EE+  + L  ++  
Sbjct: 540 REQEERREQLLKREE---EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596

Query: 238 -LWQGAERGGGER--REDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELK- 293
            L Q  +R   ER  +E+         +PE E RQ+  ++ E+EE+  +QL   + E + 
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656

Query: 294 ------KVTETLGEQLRRE 306
                 +  E L ++L+RE
Sbjct: 657 QRLKREEEEERLEQRLKRE 675



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 56/193 (29%), Positives = 92/193 (47%), Gaps = 16/193 (8%)

Query: 128  KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED----EEEEK-- 181
            +++   K R  +E++ EEE+ + E   K   QE   + +   +L QEE+    EE EK  
Sbjct: 983  RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042

Query: 182  -EERKRGPMETFEDLWQRHLENGGD---LQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237
             +ER+R   E  E+L Q   +  G+    ++R   +   ++  + Q EE+ +     ++ 
Sbjct: 1043 LQERERQYREE-EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101

Query: 238  LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKE-EASEREEKEVEQLEH--LRDE-LK 293
              Q  ER   E  E+L        + E E R+ +E E   REE+EV+Q E   LR+E  K
Sbjct: 1102 RRQERERQCREE-EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160

Query: 294  KVTETLGEQLRRE 306
            +  + L  Q R E
Sbjct: 1161 RRRQELERQYREE 1173



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 48/189 (25%), Positives = 81/189 (42%), Gaps = 17/189 (8%)

Query: 134  KMRSSQEVRDEEEEEVA---ERTHKSEVQEQAIR--------MQGHRQLHQEEDEEEEKE 182
            K R  +++R E EE+     ER  K  ++EQ +R        M+  +QL ++E +++ ++
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615

Query: 183  ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGV-----RVLGGDRS 237
            ER R   E  E L Q   E     Q+R  +   ++   + Q  E+ +     R    +  
Sbjct: 1616 ERDRKFRED-EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674

Query: 238  LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
            L Q  E     R+E          Q   + R+ K    E++ +  E     R+E +   E
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQE 1734

Query: 298  TLGEQLRRE 306
            T  EQLRR+
Sbjct: 1735 TEQEQLRRQ 1743



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 47/187 (25%), Positives = 81/187 (43%), Gaps = 19/187 (10%)

Query: 128  KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE--EEEKEERK 185
            +++   + R  +E++ EEE+ + E   K   QE   + +   ++ QEE++   EE E+R+
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162

Query: 186  RGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245
            R  +E       R      +LQ+   +   +++  + Q  E+  R    +    Q  +R 
Sbjct: 1163 RQELE-------RQYREEEELQQEEEQLLREEQEKRRQERERQYR----EEEELQRQKRK 1211

Query: 246  GGERREDLPHHHHHHHQPEAE--PRQEKEEASEREEKEVEQLE--HLRDELKK--VTETL 299
               R ED         +PE E   R  K     RE ++  QLE   LRD   +  +   L
Sbjct: 1212 QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLL 1271

Query: 300  GEQLRRE 306
            GEQ  R+
Sbjct: 1272 GEQQERD 1278



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 47/186 (25%), Positives = 88/186 (47%), Gaps = 12/186 (6%)

Query: 128  KKQEAGKMRSSQEVRDEEEEEVA--ERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERK 185
            +++E   ++  Q++R +E E+    +R  K   +EQ +  Q   +  +EE+++  ++ER+
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445

Query: 186  RGPMETFEDLWQ-RH---LENGGDLQKRVAEKASDKE-TAQFQAEEKGVRVLGGDRSLWQ 240
            R  +E  + L Q RH    E    LQ+R  ++   +E   +F  EE+ +R    DR   +
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505

Query: 241  GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300
               R     R+ L      H Q       ++E+   R+E+  ++ +   D  +K  E   
Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ---DRDRKFREE-- 1560

Query: 301  EQLRRE 306
            EQLR+E
Sbjct: 1561 EQLRQE 1566



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 39/184 (21%), Positives = 87/184 (47%), Gaps = 16/184 (8%)

Query: 128  KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE----EEEKEE 183
            ++Q+  +    ++  +EE++   ER  K   +EQ ++ +  +QLH++E +    EEE++ 
Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494

Query: 184  RKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAE 243
            R++     F +          +L+ +  E+   +E  Q   +++  + L  ++ L +  +
Sbjct: 1495 RRQERDRKFRE---------QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--Q 1543

Query: 244  RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEK-EVEQLEHLRDELKKVTETLGEQ 302
              G +RR+D         Q   E  +++    ER+ K  +E+ +  R E ++      +Q
Sbjct: 1544 ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603

Query: 303  LRRE 306
            LRR+
Sbjct: 1604 LRRQ 1607



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 40/171 (23%), Positives = 75/171 (43%), Gaps = 6/171 (3%)

Query: 136 RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDL 195
           R  Q++R E+EEE  E+  + E +E+    Q  R+     +++  +E++ R   +   + 
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405

Query: 196 WQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPH 255
             R  +     Q+   E+   +E  + + E+K  +     R   +  ER    +RE+   
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465

Query: 256 HHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
            H    + +   R ++EE  ER  K  E+      E ++  E   +QLRRE
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEE------ERREQQERREQQLRRE 510



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 41/187 (21%), Positives = 85/187 (45%), Gaps = 9/187 (4%)

Query: 127  FKKQEAGKMRSSQEVRDEEEE-EVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERK 185
            F++QE       ++  +EE++    +R  K   +EQ +R Q   Q  +++ + + +EE +
Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562

Query: 186  RGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245
                   + L ++  +    L+++   +   ++  +F  +E+ +R   G + L Q  +R 
Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRR--QEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620

Query: 246  GGERREDLPHHHHHH-HQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETL----- 299
              E  + L        H+ E + +  +EE   R ++  +QL H RD   +  E L     
Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680

Query: 300  GEQLRRE 306
             +QLRR+
Sbjct: 1681 EQQLRRQ 1687



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 48/217 (22%), Positives = 92/217 (42%), Gaps = 40/217 (18%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAER----------THKSEVQEQAIRMQGHRQL-----H 172
           K+QE  +  +  E + E++E + +R            + E QE+  R     QL     H
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199

Query: 173 QEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKE-------------- 218
           + E+  +E++ R+R  +E      +   +   + Q RV ++  +KE              
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259

Query: 219 --------TAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQE 270
                     + Q EE+ +R L  +R   +   +   ++++ L        + E E R++
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKL--ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317

Query: 271 KEEASEREEKEVEQLEHLRDELKKVTETLGE-QLRRE 306
           +EE  E++E+  +Q E    +L++  E   E QLRRE
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRRE 354



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 49/199 (24%), Positives = 84/199 (42%), Gaps = 26/199 (13%)

Query: 134  KMRSSQEVRDEEEEEVA-ERTHKSEVQEQAIRMQGHRQLHQEED-------EEEEKEERK 185
            ++R  Q++  EEEEE+  E   K   QEQ  + +   QL QEE+       E+  ++ER+
Sbjct: 898  QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957

Query: 186  RGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDR--------- 236
            R   +  +   +     G + +KR  ++   K   + + +++  ++L  +R         
Sbjct: 958  RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017

Query: 237  -------SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLR 289
                    L Q  E+   E RE            E E  Q++EE    EE+E  + + L 
Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077

Query: 290  DELKKVTETL--GEQLRRE 306
             + +K  E     EQL RE
Sbjct: 1078 RQYRKEEELQQEEEQLLRE 1096



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 53/210 (25%), Positives = 93/210 (44%), Gaps = 27/210 (12%)

Query: 118  EEKGLLLGDFKKQEAGKM----RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQ 173
            EE+ LL  + +K+   +     R   E++ EEE+ + E   K  +QE+       RQ  +
Sbjct: 999  EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER------ERQYRE 1052

Query: 174  EED-EE-------EEKEERKRGPME----TFEDLWQRH---LENGGDLQKRVAEKASDKE 218
            EE+ ++       EE+E R+R  +E      E+L Q     L    + ++R   +   +E
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112

Query: 219  TAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASERE 278
              + Q EE+ +     ++   Q  ER   E  E          +   + R+++ E   RE
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172

Query: 279  EKEVEQLEH--LRDELKKVTETLGEQLRRE 306
            E+E++Q E   LR+E +K  +    Q R E
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREE 1202



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 14/173 (8%)

Query: 136 RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERK--RGPMETFE 193
           R  Q+++ ++EEE  ER  K E +E+       +Q  +E+    E+EER+  R   +  E
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERR-----EQQERREQQLRREQEERREQRLKRQEEE 525

Query: 194 DLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDL 253
           +  Q+ L +   L++   E+   +E    + EEK +     ++ L    +R   ERR+ L
Sbjct: 526 ERLQQRLRSEQQLRREQEER---REQLLKREEEKRLEQERREQRL----KREQEERRDQL 578

Query: 254 PHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
                   Q   +  QE+      + +EVE+LE      +++     E+ RR+
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 45/177 (25%), Positives = 76/177 (42%), Gaps = 27/177 (15%)

Query: 134 KMRSSQEVRDEEE--EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMET 191
           ++R  Q++R E++   E   R  +   +EQ +R +   +  QEE+  E+K E++R     
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR---- 443

Query: 192 FEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERRE 251
            E   +R  E   D  KR      ++ET + + E +        + L +  E    ER  
Sbjct: 444 -EQRLKREQEERRDWLKR------EEETERHEQERR-------KQQLKRDQEEERRERWL 489

Query: 252 DLPHHHHHHHQPEAEPRQEKEEASEREE--KEVEQLEHLRDELKKVTETLGEQLRRE 306
            L        Q   E +  +E+   RE+  K  E+ E L+  L+       +QLRRE
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS-----EQQLRRE 541



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 40/182 (21%), Positives = 82/182 (45%), Gaps = 11/182 (6%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEE--EEEVAERTHKSEVQEQAIRMQG-----HRQ 170
           E +  LL   +++   +++  QE R E+  + E  ER  + E +EQ ++ +       +Q
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ 632

Query: 171 LHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVR 230
           L + E++EE ++++ R   +   +   +  E    L++R+  +  ++   Q  AEE+  +
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692

Query: 231 VLGGDRS---LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEH 287
                +S    WQ       + R+   +      + +   RQE+EE   R E E++  E 
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR-RQEQEEKRRRRESELQWQEE 751

Query: 288 LR 289
            R
Sbjct: 752 ER 753



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 41/182 (22%), Positives = 77/182 (42%), Gaps = 19/182 (10%)

Query: 128  KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
            +++   K+   +++R E EE+   R      QE+  + +   QL QE +E++ + +    
Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRR------QERDRKFREEEQLRQEREEQQLRSQESDR 1795

Query: 188  PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
                 E L Q   E     Q+R  +   ++E  Q + +E+ +R            ER   
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR-----------QERDRQ 1844

Query: 248  ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVT--ETLGEQLRR 305
             R E+         + E E  QE+E+   +E +   + EH+R + K+      +GE   +
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904

Query: 306  EG 307
            EG
Sbjct: 1905 EG 1906



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 29/193 (15%)

Query: 128  KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE-----KE 182
            ++Q   + +  Q + +EE+ +  ER  + + +E  ++    R+  QE+  +++     +E
Sbjct: 821  RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE 880

Query: 183  ERKR---------GPMETFEDLWQRHLENGGDLQKRVAEK-------ASDKETAQFQAEE 226
            ERKR            E      Q   E   +LQ+   EK          +E  Q Q EE
Sbjct: 881  ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940

Query: 227  KGVRVLGGDRSLWQGAERGGGERREDLPHHHHHH---HQPEAEPRQEKEEASEREEKEVE 283
            +  ++L  +R   +  ER    R++             +PE   RQE+E+   REE+E++
Sbjct: 941  E--QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK-KYREEEELQ 997

Query: 284  QLEH--LRDELKK 294
            Q E   LR+E +K
Sbjct: 998  QEEEQLLREEREK 1010



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 37/174 (21%), Positives = 81/174 (46%), Gaps = 12/174 (6%)

Query: 118  EEKGLLLGDFK----KQEAGKM-RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLH 172
            +E+  LLG+ +    +QE  +  R  +E++ EEE+ + E   K   QE+  + +   +L 
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117

Query: 173  QEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVL 232
            QEE E+  +EER++   +  E  ++   E   + ++ + E+   +   + + + +     
Sbjct: 1118 QEE-EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR----- 1171

Query: 233  GGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286
              +  L Q  E+   E +E         ++ E E +++K +   R+E +   L+
Sbjct: 1172 -EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLK 1224



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 34/220 (15%)

Query: 119  EKGLLLGDFKKQEAGKMRSSQEVRDEEEE-EVAERTHKSEVQEQAIRMQ-------GHRQ 170
            E+  LL + ++Q+  +    ++ R+EE++    ER  K   +EQ +R Q          Q
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730

Query: 171  LHQEEDEEE-EKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGV 229
            L QE ++E+  ++ER R  +E  E L     E     Q+R   K  ++E  + + EE+ +
Sbjct: 1731 LRQETEQEQLRRQERYRKILEE-EQLRPEREEQQLRRQER-DRKFREEEQLRQEREEQQL 1788

Query: 230  RVLGGDRSLWQGAE-RGGGERREDLPHHHHHHHQPEAEP----------RQEK------- 271
            R    DR   +  + R   E ++  P      ++ E E           RQE+       
Sbjct: 1789 RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE 1848

Query: 272  -----EEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
                 +E S REE+E+ Q E  +   ++  +   E +RR+
Sbjct: 1849 EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 44/190 (23%), Positives = 83/190 (43%), Gaps = 23/190 (12%)

Query: 134  KMRSSQEVRDEEEEEVAERTHKSEVQ------EQAIRMQGHRQLHQE-----EDEEEEKE 182
            K R +++ R  E+ ++ +R  + ++Q      ++  R Q  R+  Q      E+E+ E+E
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302

Query: 183  ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242
            E+K       +   ++ L     L++   EK   +ET +   EE+ +     ++ L +  
Sbjct: 1303 EQKEAKRRDRKSQEEKQL-----LREEREEKRRRQETDRKFREEEQLLQEREEQPL-RRQ 1356

Query: 243  ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQL------EHLRDELKKVT 296
            ER    R E+L H        E E R  ++E   +  KE +QL      + LR +  +  
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416

Query: 297  ETLGEQLRRE 306
                +QL R+
Sbjct: 1417 REEEQQLSRQ 1426



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 42/165 (25%), Positives = 77/165 (46%), Gaps = 17/165 (10%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
           EEK L   + +++E    R  +E RD+  +   ER  +   +EQ  R++  ++L +EE E
Sbjct: 554 EEKRL---EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE--QRLKREEVE 608

Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237
             E+EER+   ++  E   +R        Q   +E+  ++   Q + E++  R    ++ 
Sbjct: 609 RLEQEERREQRLKREEPEEERRQ------QLLKSEEQEERRQQQLRREQQERR----EQR 658

Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEV 282
           L +  E    E+R    H      Q  AE  +E+E+A ER +  +
Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAE--EEQEQARERIKSRI 701



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 42/175 (24%), Positives = 79/175 (45%), Gaps = 23/175 (13%)

Query: 119  EKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEE 178
            E+  LL + ++Q   +    ++ R EEE    E+  K   +EQ +R Q   +   +E+++
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFR-EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398

Query: 179  EEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSL 238
               +ER++   +  +D  ++  E    L ++  ++       +F+ EE+ VR        
Sbjct: 1399 LRCQEREQ---QLRQDRDRKFREEEQQLSRQERDR-------KFREEEQQVR-------- 1440

Query: 239  WQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEE----ASEREEKEVEQLEHLR 289
             Q  ER   E  + L    H   + E +  QE+EE      ER+ K +E+ + LR
Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR 1495



 Score = 37.0 bits (84), Expect = 0.022
 Identities = 40/184 (21%), Positives = 73/184 (39%), Gaps = 18/184 (9%)

Query: 136 RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--------EEEEKEERKRG 187
           R  +  R  +E+E   R  +SE+Q Q    + HRQ  +EE         + EEK ER R 
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQE-EERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782

Query: 188 PMETFEDLWQRH-----LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242
            +     L ++       E     ++R   +  +KE  + Q  E+   +    + L +  
Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL----QFLEEEE 838

Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302
           +    ER + L        + +   R +++   ++   ++E+    R         L EQ
Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898

Query: 303 LRRE 306
           LR+E
Sbjct: 899 LRKE 902



 Score = 35.8 bits (81), Expect = 0.049
 Identities = 44/182 (24%), Positives = 83/182 (45%), Gaps = 21/182 (11%)

Query: 128 KKQEAGKMRSS----------QEVRDEEEEEVAER-THKSEVQEQAIRMQGHRQLHQEED 176
           +K E G+ R S          +++R EE ++  +R   + E +EQ  R +  R+   +  
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFL 834

Query: 177 EEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVR-VLGGD 235
           EEEE+ +R+    +  E+  +  L+   + ++   ++   K   Q + E K  R  L   
Sbjct: 835 EEEEQLQRRERAQQLQEE--EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892

Query: 236 RSLWQGAERGG---GERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDEL 292
            +L +   +      E  E+L        + + + RQ +EE  E+ ++E EQL  LR+E 
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE--EQLQQEEEQL--LREER 948

Query: 293 KK 294
           +K
Sbjct: 949 EK 950



 Score = 28.5 bits (62), Expect = 7.8
 Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 1/61 (1%)

Query: 127  FKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKR 186
            F  QE  + R  QE+  EEE++  +   +   +E   R Q   Q H++  E + +E +  
Sbjct: 1851 FATQEKSR-REEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGH 1909

Query: 187  G 187
            G
Sbjct: 1910 G 1910


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 47/178 (26%), Positives = 88/178 (49%), Gaps = 21/178 (11%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           ++QE    R  +++R E+EE++ E+  K   QE+ IR Q  +   QEE+   ++E+ +  
Sbjct: 342 REQEDKMWRQEEKIR-EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
             +  E +W++  +      +   EK  ++E   ++ EEK +R L     + Q  E    
Sbjct: 401 EEKRQEKMWRQEKK-----MREQDEKIREQEEEMWRQEEK-IREL---EEMMQDQEEKLR 451

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEH---LRDELKKVTETLGEQ 302
           E  E +        Q E E  QE+EE  +R+E+++++ E     +++L K  E + EQ
Sbjct: 452 EVEEKM--------QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 50/188 (26%), Positives = 86/188 (45%), Gaps = 16/188 (8%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE-- 175
           EEK   L +  + +  K+R  +E   EEEE++ E+  K + QE+ I+ Q  +   QE+  
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492

Query: 176 DEEEEKEERKRGPMETFEDLWQRH--LENGGDLQKRVAEKASDKETAQFQAEEK----GV 229
            +EE+  E++       E +W++   ++   +  +R  EK  ++E   +Q EEK     V
Sbjct: 493 KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552

Query: 230 RVLGGDR---SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286
           R+   +     L Q AE  GG  RE           P   P  + E  S+  +   +Q +
Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRES-----GSQRLPTLTPILQVELKSQEAQSLQQQQD 607

Query: 287 HLRDELKK 294
           H R  L++
Sbjct: 608 HYRGHLQQ 615



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 43/207 (20%), Positives = 98/207 (47%), Gaps = 15/207 (7%)

Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161
           L KEL        A  EE  L      +Q+  KM   +E   E+EE++ E+  K   QE+
Sbjct: 267 LGKELQSVSAKLQAQVEENELW-NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE 325

Query: 162 AIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQ 221
            +  Q   ++H++E++  E+E++          +W++  E   + ++++ E+       +
Sbjct: 326 KMWRQ-EEKMHEQEEKIREQEDK----------MWRQE-EKIREQEEKIREQEEKMWRQE 373

Query: 222 FQAEEKGVRVLGGDRSLWQGAE--RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREE 279
            +  E+  ++   +  +W+  E  R   E+R++         + + E  +E+EE   R+E
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433

Query: 280 KEVEQLEHLRDELKKVTETLGEQLRRE 306
           +++ +LE +  + ++    + E+++ E
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEE 460



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 41/185 (22%), Positives = 87/185 (47%), Gaps = 8/185 (4%)

Query: 128 KKQEAGKMRSSQEVRDEEE---EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184
           ++QE    R  +++R++EE   E++  +  K   Q++ IR Q   ++ ++E++  E EE 
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ-EEEMWRQEEKIRELEEM 442

Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEE--KGVRVLGGDRSLWQGA 242
            +   E   ++ ++  E    +Q++  +    +E  Q Q E+  +  ++L  +  +W+  
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502

Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302
           E+    R+E+         Q + E  Q +EE    +E  + Q E    E +   + L E+
Sbjct: 503 EKMW--RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560

Query: 303 LRREG 307
           L + G
Sbjct: 561 LGKLG 565



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 40/179 (22%), Positives = 88/179 (49%), Gaps = 15/179 (8%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           ++QE    R  +++R E++E++ E+  +   QE+ IR Q  ++  +   +E++  E+   
Sbjct: 363 REQEEKMWRQEEKIR-EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK 421

Query: 188 PMETFEDLWQRH---------LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSL 238
             E  E++W++          +++  +  + V EK  ++E    + EEK  R    +  +
Sbjct: 422 IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ---EEKI 478

Query: 239 WQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
            +  E+    R+E L        + E +  +++E+  E+EEK  EQ E ++ + +K+ E
Sbjct: 479 QEQEEKTW--RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 54/239 (22%), Positives = 100/239 (41%), Gaps = 24/239 (10%)

Query: 88  LTVGQV--QRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEE 145
           L +G+V  Q+ P  +LL + L         +  EK     D    E  +   + E   E+
Sbjct: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEK 219

Query: 146 EEEVAER-----THKSEVQ----------EQAIRMQGHRQLHQEED---EEEEKEERKRG 187
             E+ E+     + KSE+Q          E+A  +   +QL  E D   +E +    K  
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
                 +LW    +   +   R  EK  ++E    + E   +++   +  +W+  E+   
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE---LKIREQEEKMWRQEEKMH- 335

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
           E+ E +        + E + R+++E+  E+EEK   Q E +R++ +K+ E   E  R+E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE 394


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 47/178 (26%), Positives = 88/178 (49%), Gaps = 21/178 (11%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           ++QE    R  +++R E+EE++ E+  K   QE+ IR Q  +   QEE+   ++E+ +  
Sbjct: 342 REQEDKMWRQEEKIR-EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
             +  E +W++  +      +   EK  ++E   ++ EEK +R L     + Q  E    
Sbjct: 401 EEKRQEKMWRQEKK-----MREQDEKIREQEEEMWRQEEK-IREL---EEMMQDQEEKLR 451

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEH---LRDELKKVTETLGEQ 302
           E  E +        Q E E  QE+EE  +R+E+++++ E     +++L K  E + EQ
Sbjct: 452 EVEEKM--------QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 50/188 (26%), Positives = 86/188 (45%), Gaps = 16/188 (8%)

Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE-- 175
           EEK   L +  + +  K+R  +E   EEEE++ E+  K + QE+ I+ Q  +   QE+  
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492

Query: 176 DEEEEKEERKRGPMETFEDLWQRH--LENGGDLQKRVAEKASDKETAQFQAEEK----GV 229
            +EE+  E++       E +W++   ++   +  +R  EK  ++E   +Q EEK     V
Sbjct: 493 KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552

Query: 230 RVLGGDR---SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286
           R+   +     L Q AE  GG  RE           P   P  + E  S+  +   +Q +
Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRES-----GSQRLPTLTPILQVELKSQEAQSLQQQQD 607

Query: 287 HLRDELKK 294
           H R  L++
Sbjct: 608 HYRGHLQQ 615



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 43/207 (20%), Positives = 98/207 (47%), Gaps = 15/207 (7%)

Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161
           L KEL        A  EE  L      +Q+  KM   +E   E+EE++ E+  K   QE+
Sbjct: 267 LGKELQSVSAKLQAQVEENELW-NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE 325

Query: 162 AIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQ 221
            +  Q   ++H++E++  E+E++          +W++  E   + ++++ E+       +
Sbjct: 326 KMWRQ-EEKMHEQEEKIREQEDK----------MWRQE-EKIREQEEKIREQEEKMWRQE 373

Query: 222 FQAEEKGVRVLGGDRSLWQGAE--RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREE 279
            +  E+  ++   +  +W+  E  R   E+R++         + + E  +E+EE   R+E
Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433

Query: 280 KEVEQLEHLRDELKKVTETLGEQLRRE 306
           +++ +LE +  + ++    + E+++ E
Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEE 460



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 41/185 (22%), Positives = 87/185 (47%), Gaps = 8/185 (4%)

Query: 128 KKQEAGKMRSSQEVRDEEE---EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184
           ++QE    R  +++R++EE   E++  +  K   Q++ IR Q   ++ ++E++  E EE 
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ-EEEMWRQEEKIRELEEM 442

Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEE--KGVRVLGGDRSLWQGA 242
            +   E   ++ ++  E    +Q++  +    +E  Q Q E+  +  ++L  +  +W+  
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502

Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302
           E+    R+E+         Q + E  Q +EE    +E  + Q E    E +   + L E+
Sbjct: 503 EKMW--RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560

Query: 303 LRREG 307
           L + G
Sbjct: 561 LGKLG 565



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 40/179 (22%), Positives = 88/179 (49%), Gaps = 15/179 (8%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           ++QE    R  +++R E++E++ E+  +   QE+ IR Q  ++  +   +E++  E+   
Sbjct: 363 REQEEKMWRQEEKIR-EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK 421

Query: 188 PMETFEDLWQRH---------LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSL 238
             E  E++W++          +++  +  + V EK  ++E    + EEK  R    +  +
Sbjct: 422 IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ---EEKI 478

Query: 239 WQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
            +  E+    R+E L        + E +  +++E+  E+EEK  EQ E ++ + +K+ E
Sbjct: 479 QEQEEKTW--RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 54/239 (22%), Positives = 100/239 (41%), Gaps = 24/239 (10%)

Query: 88  LTVGQV--QRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEE 145
           L +G+V  Q+ P  +LL + L         +  EK     D    E  +   + E   E+
Sbjct: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEK 219

Query: 146 EEEVAER-----THKSEVQ----------EQAIRMQGHRQLHQEED---EEEEKEERKRG 187
             E+ E+     + KSE+Q          E+A  +   +QL  E D   +E +    K  
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
                 +LW    +   +   R  EK  ++E    + E   +++   +  +W+  E+   
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE---LKIREQEEKMWRQEEKMH- 335

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
           E+ E +        + E + R+++E+  E+EEK   Q E +R++ +K+ E   E  R+E
Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE 394


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
           sapiens]
          Length = 1152

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 50/184 (27%), Positives = 74/184 (40%), Gaps = 6/184 (3%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTH----KSEVQEQAIRMQGHRQLHQEEDEEEEKEE 183
           +K E  K R   E   E E+E+AE+        E QEQ  R QGH++   +E EE  +EE
Sbjct: 675 EKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEE 734

Query: 184 RKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAE 243
              G  E  +   +   E  G  +    E   ++E  +   E K     G +    +  +
Sbjct: 735 HGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEE--GERKKEERAGKEEKGEEEGD 792

Query: 244 RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQL 303
           +G GE  E            E E  + +E   EREE+E E      +   +  E  GE+ 
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE 852

Query: 304 RREG 307
             EG
Sbjct: 853 EGEG 856



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 53/204 (25%), Positives = 86/204 (42%), Gaps = 6/204 (2%)

Query: 108  GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167
            G E  G    EE+G      ++ E G+    +E  + E EE  E   + E  E     +G
Sbjct: 849  GEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG 908

Query: 168  HRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENG-GDLQKRVAEKASDKETAQFQAEE 226
              +  +EE E + +EE + G  E  E+  +   E+G G+ ++   E   ++E  + + EE
Sbjct: 909  EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968

Query: 227  KGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASERE---EKEVE 283
            +G     G+    +G E  G    E+         + E E   E E   E E   E EVE
Sbjct: 969  EGEGE--GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVE 1026

Query: 284  QLEHLRDELKKVTETLGEQLRREG 307
              E   +  ++  E  GE+  +EG
Sbjct: 1027 GEEGEGEGEEEEGEEEGEEREKEG 1050



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 55/216 (25%), Positives = 84/216 (38%), Gaps = 25/216 (11%)

Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167
           G +  G    E  G    +  ++E  K R  +E   +E E+  ++    E++E      G
Sbjct: 677 GEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG 736

Query: 168 HRQLHQ---EEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQA 224
             +  +   EE+EE+E E ++ G  E  E   +R  E G   ++  A K    E    Q 
Sbjct: 737 EGEEEEGDREEEEEKEGEGKEEGEGEEVEG--EREKEEGERKKEERAGKEEKGEEEGDQG 794

Query: 225 E-------------EKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEK 271
           E             E+G  V GG+       E G GER E+         + E E  + +
Sbjct: 795 EGEEEETEGRGEEKEEGGEVEGGE------VEEGKGEREEEEEEGEGEEEEGEGEEEEGE 848

Query: 272 EEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307
            E  E E K  E+ E    E ++  E  GE    EG
Sbjct: 849 GEEEEGEGKGEEEGEEGEGE-EEGEEGEGEGEEEEG 883



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 2/180 (1%)

Query: 108  GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167
            G E  G    EE+G   G+ + +E       +E   E EEE  E   + E + +    +G
Sbjct: 842  GEEEEG-EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 900

Query: 168  HRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEK 227
              +  +E + E E+EE +    E  E+      E  G+ +    E   ++E  +++ EE+
Sbjct: 901  EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960

Query: 228  GVRVLGGDRSLWQGAE-RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286
                 G +    +G E  G GE  E          + E E   E EE  E E +E E+ E
Sbjct: 961  EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 8/193 (4%)

Query: 118  EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177
            EE G + G   ++  G+    +E  + EEEE      + E +E+    +G  +  + E E
Sbjct: 809  EEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868

Query: 178  EEEKEERKRGPMETFEDLWQRHLENGGDLQ------KRVAEKASDKETAQFQAEEKGVRV 231
            EE +E    G  E  E   +   E  G+ +      +   E   ++E  + + EE+G   
Sbjct: 869  EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928

Query: 232  LG-GDRSLWQG-AERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLR 289
             G G+    +G  E G GE  E+         + E E  +E E   E  E E E+ E   
Sbjct: 929  EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988

Query: 290  DELKKVTETLGEQ 302
            +  ++  E  GE+
Sbjct: 989  EGEEEEGEEEGEE 1001



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 49/199 (24%), Positives = 78/199 (39%), Gaps = 6/199 (3%)

Query: 108  GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAE---RTHKSEVQEQAIR 164
            G E  G    EE+G   G+ ++ E       +E   E EEE  E      + E +E+   
Sbjct: 895  GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE 954

Query: 165  MQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQA 224
             +G  +  + E EEE + E + G  E  E+  +   E     ++   E   ++E      
Sbjct: 955  WEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGE 1014

Query: 225  EEKGVRVLG---GDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKE 281
            EE+   V G   G+    +G E  G E  E+                +E+EE   +E  E
Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE 1074

Query: 282  VEQLEHLRDELKKVTETLG 300
             E      +E KKV++  G
Sbjct: 1075 EENERQDGEEYKKVSKIKG 1093



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 41/184 (22%), Positives = 80/184 (43%), Gaps = 15/184 (8%)

Query: 128 KKQEAGKMRSSQEVRDE---EEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184
           K +  G+     E R +   EE        + E +E+  + +G  ++ +  + E+E  E+
Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEK 699

Query: 185 KRGPMETFEDLWQRHLENGGDLQK-RVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAE 243
           +       E+  Q+  E G   ++ +  E+  ++E  + + EE       GDR   +  E
Sbjct: 700 EEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE-------GDR---EEEE 749

Query: 244 RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQL 303
              GE +E+         + + E  ++KEE + +EEK  E+ +    E ++ TE  GE+ 
Sbjct: 750 EKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE-EEETEGRGEEK 808

Query: 304 RREG 307
              G
Sbjct: 809 EEGG 812



 Score = 36.6 bits (83), Expect = 0.029
 Identities = 47/175 (26%), Positives = 74/175 (42%), Gaps = 27/175 (15%)

Query: 137 SSQEVRDEEEEEVAERTHKSEVQEQA-------IRMQGHRQLHQE--EDEEEEKEERKRG 187
           S +EV   EE+E AE +  + ++EQ        +++ G R+   E   D+  +K E   G
Sbjct: 580 SDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEG 639

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLG---------GDRSL 238
             ++  +  +   E  GD      E +S  E  Q +  EKG +  G         G++ L
Sbjct: 640 KAKSVGEA-EDGPEGRGD--GTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKEL 696

Query: 239 WQGAE--RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE 291
            +  E  +  GE +E       H    + E  QE EE  E E  E E+ E  R+E
Sbjct: 697 AEKEEWKKRDGEEQEQKEREQGH----QKERNQEMEEGGEEEHGEGEEEEGDREE 747



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 55/234 (23%), Positives = 94/234 (40%), Gaps = 46/234 (19%)

Query: 116 STEEKGLLLGDFKKQEA----GKMRSSQEVRD----EEEEEVAE----RTHKSEVQEQAI 163
           ++ EK L L   +KQ+     G++     + +    +E EE++E    +  K  V +   
Sbjct: 509 NSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIF 568

Query: 164 RMQGHRQLHQEEDEEEEKEERKRGPMET-----FEDLWQRHLEN----GGDLQKRVAEKA 214
             Q    +    DEE E  E K G  ++      E   + + EN    GG  +K   E  
Sbjct: 569 MTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGG--RKEKTEIL 626

Query: 215 SDKETAQFQAEEKGVRVLG---------GDRSL---------WQGAERGGGER---REDL 253
           SD  T + +  E   + +G         GD +          WQ  ER  GE+   R ++
Sbjct: 627 SDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEM 686

Query: 254 PHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307
                   +   +   +K +  E+E+KE EQ  H ++  +++ E  GE+   EG
Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQKEREQ-GHQKERNQEMEEG-GEEEHGEG 738


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 11/159 (6%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGP 188
           K EA K++   +  +E  EE      KSE++E    +     +  +E+++E  EE++  P
Sbjct: 440 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 499

Query: 189 METFEDLWQRHLE---NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245
               E++  +         ++++   EK  ++   + + E++G +           AE G
Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKS--------DQAEEG 551

Query: 246 GGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQ 284
           G E+            + E E   E EEA  +EEK+VE+
Sbjct: 552 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 590



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 21/192 (10%)

Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167
           G  P   +  EEKG       K    +   S   +   EE+      KS V+E   + + 
Sbjct: 639 GKSPVPKSPVEEKGK--SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV 696

Query: 168 HRQLHQEEDEEEEKEERKRGPMETFE----DLWQRHLENGGDLQKRVA------------ 211
            +   +EE+E+E KE  K   +E  E    D+ ++        ++ VA            
Sbjct: 697 GKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVH 756

Query: 212 -EKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG-GERREDLPHHHHHHHQPEAEPRQ 269
            EK + +E    Q E++  +  G   S  +G+++G  G R+ED+  +     + E E ++
Sbjct: 757 LEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE-QE 815

Query: 270 EKEEASEREEKE 281
            KE+ S REE++
Sbjct: 816 TKEKGSGREEEK 827



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 13/115 (11%)

Query: 115 ASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQE 174
           A TEE  + + + KK+ A      +E  + EEEEVA +    +     ++ +   +  +E
Sbjct: 475 AITEELAVSMKEEKKEAA---EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEE 531

Query: 175 EDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEK-ASDKETAQFQAEEKG 228
             EEEE+E+         E       E GG  ++  +EK   ++E  + +AE +G
Sbjct: 532 GQEEEEEED---------EGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG 577



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 41/215 (19%), Positives = 79/215 (36%), Gaps = 54/215 (25%)

Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVR--DEEEEEVA--------------- 150
           G+E  G +  EE     G+ + +  G+   ++E +  +E+ EEVA               
Sbjct: 552 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 611

Query: 151 -----------ERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRH 199
                      E   KS V +  +  +G   + +   EE+ K    + P+E         
Sbjct: 612 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEE-------- 663

Query: 200 LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHH 259
            +    + K   E+ +     +   EE   +           AE G GE++E+       
Sbjct: 664 -KGKSPVSKSPVEEKAKSPVPKSPVEEAKSK-----------AEVGKGEQKEE------E 705

Query: 260 HHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294
             + +  P++EK E  E + K+V + +     +K+
Sbjct: 706 EKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 740



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 31/137 (22%), Positives = 55/137 (40%), Gaps = 15/137 (10%)

Query: 73  KEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEA 132
           K E+   L   +TE L V   +     A   +E    E    A+ +          K+E 
Sbjct: 466 KSEMEEALT-AITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE 524

Query: 133 GKMRSSQEVRDEEEEEVAERTHKSEV----------QEQAIRMQGHRQLHQEEDE----E 178
           G+    +   +EEEE+   ++ ++E           +E+  + +G  +   E +E    E
Sbjct: 525 GEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKE 584

Query: 179 EEKEERKRGPMETFEDL 195
           E+K E K   + T E+L
Sbjct: 585 EKKVEEKSEEVATKEEL 601


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 11/159 (6%)

Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGP 188
           K EA K++   +  +E  EE      KSE++E    +     +  +E+++E  EE++  P
Sbjct: 64  KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 123

Query: 189 METFEDLWQRHLE---NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245
               E++  +         ++++   EK  ++   + + E++G +           AE G
Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKS--------DQAEEG 175

Query: 246 GGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQ 284
           G E+            + E E   E EEA  +EEK+VE+
Sbjct: 176 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 214



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 21/192 (10%)

Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167
           G  P   +  EEKG       K    +   S   +   EE+      KS V+E   + + 
Sbjct: 263 GKSPVPKSPVEEKGK--SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV 320

Query: 168 HRQLHQEEDEEEEKEERKRGPMETFE----DLWQRHLENGGDLQKRVA------------ 211
            +   +EE+E+E KE  K   +E  E    D+ ++        ++ VA            
Sbjct: 321 GKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVH 380

Query: 212 -EKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG-GERREDLPHHHHHHHQPEAEPRQ 269
            EK + +E    Q E++  +  G   S  +G+++G  G R+ED+  +     + E E ++
Sbjct: 381 LEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE-QE 439

Query: 270 EKEEASEREEKE 281
            KE+ S REE++
Sbjct: 440 TKEKGSGREEEK 451



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 13/115 (11%)

Query: 115 ASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQE 174
           A TEE  + + + KK+ A      +E  + EEEEVA +    +     ++ +   +  +E
Sbjct: 99  AITEELAVSMKEEKKEAA---EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEE 155

Query: 175 EDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEK-ASDKETAQFQAEEKG 228
             EEEE+E+         E       E GG  ++  +EK   ++E  + +AE +G
Sbjct: 156 GQEEEEEED---------EGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG 201



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 41/215 (19%), Positives = 79/215 (36%), Gaps = 54/215 (25%)

Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVR--DEEEEEVA--------------- 150
           G+E  G +  EE     G+ + +  G+   ++E +  +E+ EEVA               
Sbjct: 176 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 235

Query: 151 -----------ERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRH 199
                      E   KS V +  +  +G   + +   EE+ K    + P+E         
Sbjct: 236 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEE-------- 287

Query: 200 LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHH 259
            +    + K   E+ +     +   EE   +           AE G GE++E+       
Sbjct: 288 -KGKSPVSKSPVEEKAKSPVPKSPVEEAKSK-----------AEVGKGEQKEE------E 329

Query: 260 HHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294
             + +  P++EK E  E + K+V + +     +K+
Sbjct: 330 EKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 364



 Score = 28.9 bits (63), Expect = 6.0
 Identities = 31/137 (22%), Positives = 55/137 (40%), Gaps = 15/137 (10%)

Query: 73  KEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEA 132
           K E+   L   +TE L V   +     A   +E    E    A+ +          K+E 
Sbjct: 90  KSEMEEALT-AITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE 148

Query: 133 GKMRSSQEVRDEEEEEVAERTHKSEV----------QEQAIRMQGHRQLHQEEDE----E 178
           G+    +   +EEEE+   ++ ++E           +E+  + +G  +   E +E    E
Sbjct: 149 GEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKE 208

Query: 179 EEKEERKRGPMETFEDL 195
           E+K E K   + T E+L
Sbjct: 209 EKKVEEKSEEVATKEEL 225


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 41/167 (24%), Positives = 77/167 (46%), Gaps = 8/167 (4%)

Query: 140 EVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRH 199
           E+R+ E E    +  K E + +  R +  R+  + + E E++ +R+RG  E   +  ++ 
Sbjct: 37  EIREREREIETRKEGKKERESE--RKKERREREKRKREREKERKRERGKKEKKGE--RKK 92

Query: 200 LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHH 259
            E     ++R  E    +E  + + +EK  R     R+  +G ER   E R+        
Sbjct: 93  EERERKKRRREKENKEGEEKEKRKKKEKKER----GRTSKEGKERERKEERKREERKERE 148

Query: 260 HHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306
             + E E  +E++E  +RE K+V + E  R E ++      E+ R+E
Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 37/174 (21%), Positives = 81/174 (46%), Gaps = 20/174 (11%)

Query: 125 GDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184
           G+ KK+E  + +  +E  ++E EE  +R  K + +      +G  +  +EE + EE++ER
Sbjct: 88  GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147

Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAER 244
           +R   E  ++  +   E     +K+V EK  +++  + +  +K               ER
Sbjct: 148 ERKKEEREKE--RERKERKKRERKQVGEKEEERKEKERKERKK--------------RER 191

Query: 245 GGGERREDLPHHHHHHHQPEAEPRQEKEEASEREE----KEVEQLEHLRDELKK 294
              ER+++         + E + ++E+++  +++     +E E+ +  R E KK
Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 34/167 (20%), Positives = 76/167 (45%), Gaps = 7/167 (4%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           KK+   + +  +E   E + E  ++  K E +++  R +  R+  +E  E EEKE+RK+ 
Sbjct: 60  KKERREREKRKREREKERKRERGKKEKKGERKKEE-RERKKRRREKENKEGEEKEKRKKK 118

Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247
             +       R  + G + +++   K  +++  + + EE+       +R   +   +  G
Sbjct: 119 EKKE----RGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK--KRERKQVG 172

Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294
           E+ E+         +     R+E+++  ER+E+   + E  + E +K
Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERK 219



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 29/153 (18%), Positives = 69/153 (45%), Gaps = 15/153 (9%)

Query: 155 KSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKA 214
           +SE++E+   ++  ++  +E + E +KE R+R   +   +            ++R  E+ 
Sbjct: 35  QSEIREREREIETRKEGKKERESERKKERREREKRKRERE------------KERKRERG 82

Query: 215 SDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEA 274
             ++  + + EE+  +    ++   +G E+   E+R+            E + R+ KEE 
Sbjct: 83  KKEKKGERKKEERERKKRRREKENKEGEEK---EKRKKKEKKERGRTSKEGKERERKEER 139

Query: 275 SEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307
              E KE E+ +  R++ ++  E    + ++ G
Sbjct: 140 KREERKERERKKEEREKERERKERKKRERKQVG 172



 Score = 35.4 bits (80), Expect = 0.064
 Identities = 31/139 (22%), Positives = 60/139 (43%), Gaps = 20/139 (14%)

Query: 113 GCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLH 172
           G  S E K     + +K+E  K R  ++   E+E E  ER           + +  +Q+ 
Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKER-----------KKRERKQVG 172

Query: 173 QEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVL 232
           ++E+E +EKE ++R   E      ++  E     +++   K  ++   + Q +       
Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR------ 226

Query: 233 GGDRSLWQGAERGGGERRE 251
              ++ W+  ERG  ER+E
Sbjct: 227 ---QTNWREKERGKRERKE 242


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 52/203 (25%), Positives = 85/203 (41%), Gaps = 28/203 (13%)

Query: 105 ELCGTEPHGCAS-TEEKGLLLGDFKKQEAGKMRSSQ-----EVRDEEEEEVAERTHKSEV 158
           EL    P   +S +EEKG    D +K   G+ RSS+       +  E  + AE     E 
Sbjct: 197 ELSRHSPRKSSSISEEKGD--SDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQET 254

Query: 159 QEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE--------NGGDLQKRV 210
             + +R++  R L  EE+EEEE+EE +    E  +D  Q+  E          G+   RV
Sbjct: 255 PSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRV 314

Query: 211 AEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQE 270
             +    E  + +++E+ V             ERGG   R        H  + + E   +
Sbjct: 315 KPEEMMDERPKTRSQEQEV------------LERGGRFTRSQEEARKSHLARQQQEKEMK 362

Query: 271 KEEASEREEKEVEQLEHLRDELK 293
                E EE+E++  + L+++ K
Sbjct: 363 TTSPLEEEEREIKSSQGLKEKSK 385



 Score = 35.8 bits (81), Expect = 0.049
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 2/103 (1%)

Query: 128  KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
            ++ E  K R  +  +++EEEE  ER  ++E +      +  R+ H  E + E + ER+R 
Sbjct: 1240 ERAERAKEREKRR-KEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERD 1298

Query: 188  PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVR 230
              +   D  +R  E G +  +R  ++ S   +      ++G R
Sbjct: 1299 RGDRDRDR-ERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGR 1340



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 12/97 (12%)

Query: 160  EQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKET 219
            E+A R +   +  +E++EEE+KE  K    E       R LE     ++R   +  D+E 
Sbjct: 1240 ERAERAKEREKRRKEQEEEEQKEREKEAERER-----NRQLERE---KRREHSRERDRER 1291

Query: 220  AQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHH 256
             + +  ++G R    DR   +  ERG    R D   H
Sbjct: 1292 ERERERDRGDR----DRDRERDRERGRERDRRDTKRH 1324



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 42/185 (22%), Positives = 74/185 (40%), Gaps = 24/185 (12%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQL----HQEEDEEEEKEE 183
           K+QE  + R  +E R+  E E A     +E +++ I  +G   L     Q   E  E E 
Sbjct: 143 KQQELLRQRLEREAREAAELEEAS----AESEDEMIHPEGVASLLPPDFQSSLERPELEL 198

Query: 184 RKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAE 243
            +  P ++         E  GD       K   + +   QA             L +G++
Sbjct: 199 SRHSPRKS-----SSISEEKGDSDDEKPRKGERRSSRVRQARAA---------KLSEGSQ 244

Query: 244 RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTET-LGEQ 302
               E  ++ P  +    + +   + E+EE  E EE+E ++ E   DE +K  E  + ++
Sbjct: 245 PAEEEEDQETPSRNLRV-RADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKE 303

Query: 303 LRREG 307
            + EG
Sbjct: 304 FKEEG 308


>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
           [Homo sapiens]
          Length = 213

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 10/182 (5%)

Query: 126 DFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERK 185
           D  K+   + R S+  R  + E   ER    E ++Q  R +G RQ  +E D + ++E  +
Sbjct: 32  DRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDR-EGERQRERERDRDRQRETER 90

Query: 186 RGPMETFEDLWQRHLENGGDLQK---RVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242
               E   D   RH E   + QK   R  E+  D+E  +   +E G R    DR   +  
Sbjct: 91  ERDKERETD---RHTETDRERQKQKEREMERVRDREREK--QKEMG-RERQTDRETDRER 144

Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302
           ER     RE            E E  +++E   +RE KE E+   +  E ++ T+   ++
Sbjct: 145 ERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDR 204

Query: 303 LR 304
            R
Sbjct: 205 QR 206



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 40/167 (23%), Positives = 62/167 (37%), Gaps = 10/167 (5%)

Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFE 193
           + R +   RD  +E   E  H SE   Q  R    R   ++ D E EK+  + G  +   
Sbjct: 23  RRRETDRERDRAKESKTEDRH-SERDRQRDR---ERNRERDRDREREKQTDREGERQRER 78

Query: 194 DL---WQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250
           +     QR  E   D ++            Q Q E +  RV   +R   +  +  G ER+
Sbjct: 79  ERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRER---EKQKEMGRERQ 135

Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
            D         Q E E    +E  +E   +E E+      E K+ T+
Sbjct: 136 TDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETK 182


>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
          Length = 514

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 42/165 (25%), Positives = 84/165 (50%), Gaps = 15/165 (9%)

Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQ---EQAIRMQGHRQLHQEEDEEEEKEERKRGPME 190
           K ++ QE R   ++ + ER    + +   EQ + M+  ++  Q+  EE +K+++KR  M 
Sbjct: 277 KQKAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMI 336

Query: 191 TFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250
             + ++ ++L      Q+R  EKA +KE  +   E+K  ++   D+ L     R   E R
Sbjct: 337 REQKIYHKYLA-----QRREEEKAQEKEFDRILEEDKAKKLAEKDKEL-----RLEKEAR 386

Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKV 295
             L        + + + + ++ EA E+EE+ +EQ +H+ + LK++
Sbjct: 387 RQLVDEVMCTRKLQVQEKLQR-EAKEQEERAMEQ-KHINESLKEL 429



 Score = 30.0 bits (66), Expect = 2.7
 Identities = 16/52 (30%), Positives = 31/52 (59%), Gaps = 1/52 (1%)

Query: 137 SSQEVRDEEEEEVAERTHKSEVQEQAIRMQ-GHRQLHQEEDEEEEKEERKRG 187
           S +E+  EE+E  A R   ++   + ++MQ  ++Q  QE ++EE++ E + G
Sbjct: 425 SLKELNCEEKENFARRQRLAQEYRKQLQMQIAYQQQSQEAEKEEKRREFEAG 476


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 41/167 (24%), Positives = 72/167 (43%), Gaps = 27/167 (16%)

Query: 134 KMRSSQEVRDEEEEEVAERT---HKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPME 190
           K  S +E+R+ E E+  ER     K + QE+    +  R+  QE+++E EKE+ K+  ME
Sbjct: 497 KQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME 556

Query: 191 TFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250
                 +R  E   +L++   +K  +KE  + + +EK   +                E+ 
Sbjct: 557 K-----ERKQEKEKELER---QKEKEKELQKMKEQEKECEL----------------EKE 592

Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297
            +         +P  EP  EK+E+     KE E +   +D  +   E
Sbjct: 593 REKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKE 639



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 36/167 (21%)

Query: 142 RDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE 201
           R EEEE   E   K+   E+  R+     + +++   EE  ER+R      E   ++  E
Sbjct: 465 RREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQE 524

Query: 202 NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHH 261
                Q+R  E+  D+E  Q                          E+ ++L        
Sbjct: 525 -----QEREKEREKDRERQQ--------------------------EKEKELEKEQEKQR 553

Query: 262 QPEAEPRQEKEEASEREEKEVEQLEHLRD-----ELKKVTETLGEQL 303
           + E E +QEKE+  ER++++ ++L+ +++     EL+K  E L E++
Sbjct: 554 EMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI 600



 Score = 38.5 bits (88), Expect = 0.008
 Identities = 40/162 (24%), Positives = 67/162 (41%), Gaps = 34/162 (20%)

Query: 133 GKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETF 192
           G   S Q+V DE+E     R  +SE+     R +  R    EE+E   +E+RK    E  
Sbjct: 430 GPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRR----EEEERRMEEQRKAACAEKL 485

Query: 193 EDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERRED 252
           + L         D +  + EK    E  + +  EK               ER   ER ++
Sbjct: 486 KRL---------DEKLGILEKQPSPEEIREREREK---------------ER---EREKE 518

Query: 253 LPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294
           L        + E E  +E+++    +EKE+E+ +  + E++K
Sbjct: 519 LEKEQEQEREKEREKDRERQQ---EKEKELEKEQEKQREMEK 557



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 9/101 (8%)

Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187
           +++E  + R  +  +++E+E   ER    E Q++  +     Q  Q E E+E K+E+   
Sbjct: 507 REREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK--- 563

Query: 188 PMETFEDLWQRHLENGGDLQK-RVAEKASDKETAQFQAEEK 227
                E   +R  E   +LQK +  EK  + E  + + EEK
Sbjct: 564 -----EKELERQKEKEKELQKMKEQEKECELEKEREKLEEK 599



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 29/168 (17%), Positives = 73/168 (43%), Gaps = 11/168 (6%)

Query: 128 KKQEAGKMRSSQEVRDEEEE-EVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE----KE 182
           ++QE  K R     R +E+E E+ +   K    E+  + +  ++L +++++E+E    KE
Sbjct: 523 QEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKE 582

Query: 183 ERKRGPMETFEDLWQRHLENGGD-----LQKRVAEKASDKETAQ-FQAEEKGVRVLGGDR 236
           + K   +E   +  +  +E         ++K+ +E + +KE    F  ++          
Sbjct: 583 QEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATP 642

Query: 237 SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQ 284
            + +     G + R  +   +    Q    PR ++++   ++++  +Q
Sbjct: 643 VVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ 690



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 33/144 (22%), Positives = 58/144 (40%), Gaps = 9/144 (6%)

Query: 151  ERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRV 210
            ER    E Q    R   H   H ++ +E+  E     P  T      R +++   +++  
Sbjct: 910  ERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVT-----SRCIDSKEPIER-- 962

Query: 211  AEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEP--R 268
             E+   KE     +E      +   +S  +   R    RRE++         P  +P  R
Sbjct: 963  PEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLR 1022

Query: 269  QEKEEASEREEKEVEQLEHLRDEL 292
              KEE  +R+EKE E+ E + +++
Sbjct: 1023 DMKEEREQRKEKEGEKAEKVTEKV 1046


>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 625

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 64/286 (22%), Positives = 111/286 (38%), Gaps = 24/286 (8%)

Query: 33  GAGERGLQWEGAGSA----PSGEASGAEPPAGDTTAAPLAPRPSKEELTRCLAEVVTEVL 88
           G   R L+W    SA    P+G AS      G  +A  L P   +   +  L ++     
Sbjct: 272 GESLRELRWPPRASARNSCPAGSASSTTNAPGRPSALTLVPITGR---SFSLGDLSHSPQ 328

Query: 89  TVGQVQRGPCTALLHKELCGTEPHG------CASTEEKGLLLGDFKKQEAGKMRSSQ-EV 141
           T   V+R        + L G             +  ++ LLL + +    G+    +   
Sbjct: 329 TAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQWELQRVHA 388

Query: 142 RDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE 201
           +   E E  E+    E   +A   Q   +  +   EE E   R++   E  E+  +   E
Sbjct: 389 KQRREREEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAE 448

Query: 202 NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHH 261
             G L++  AE+A+ ++  +   +E+ ++    +  L +G ER    RRE          
Sbjct: 449 RQGLLRRERAERAAREDRLRKLQQEQNLKQR--EEGLQEGRERAEQIRRE--------RA 498

Query: 262 QPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307
           Q  A  +Q +E   +RE++E+ + E  R E      T  ++  REG
Sbjct: 499 QRAARAKQRQEGQLQREKRELSRAERARHEALLQGRTRQQRQEREG 544


>gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 627

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 64/286 (22%), Positives = 111/286 (38%), Gaps = 24/286 (8%)

Query: 33  GAGERGLQWEGAGSA----PSGEASGAEPPAGDTTAAPLAPRPSKEELTRCLAEVVTEVL 88
           G   R L+W    SA    P+G AS      G  +A  L P   +   +  L ++     
Sbjct: 274 GESLRELRWPPRASARNSCPAGSASSTTNAPGRPSALTLVPITGR---SFSLGDLSHSPQ 330

Query: 89  TVGQVQRGPCTALLHKELCGTEPHG------CASTEEKGLLLGDFKKQEAGKMRSSQ-EV 141
           T   V+R        + L G             +  ++ LLL + +    G+    +   
Sbjct: 331 TAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQWELQRVHA 390

Query: 142 RDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE 201
           +   E E  E+    E   +A   Q   +  +   EE E   R++   E  E+  +   E
Sbjct: 391 KQRREREEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAE 450

Query: 202 NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHH 261
             G L++  AE+A+ ++  +   +E+ ++    +  L +G ER    RRE          
Sbjct: 451 RQGLLRRERAERAAREDRLRKLQQEQNLKQR--EEGLQEGRERAEQIRRE--------RA 500

Query: 262 QPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307
           Q  A  +Q +E   +RE++E+ + E  R E      T  ++  REG
Sbjct: 501 QRAARAKQRQEGQLQREKRELSRAERARHEALLQGRTRQQRQEREG 546


>gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 627

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 64/286 (22%), Positives = 111/286 (38%), Gaps = 24/286 (8%)

Query: 33  GAGERGLQWEGAGSA----PSGEASGAEPPAGDTTAAPLAPRPSKEELTRCLAEVVTEVL 88
           G   R L+W    SA    P+G AS      G  +A  L P   +   +  L ++     
Sbjct: 274 GESLRELRWPPRASARNSCPAGSASSTTNAPGRPSALTLVPITGR---SFSLGDLSHSPQ 330

Query: 89  TVGQVQRGPCTALLHKELCGTEPHG------CASTEEKGLLLGDFKKQEAGKMRSSQ-EV 141
           T   V+R        + L G             +  ++ LLL + +    G+    +   
Sbjct: 331 TAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQWELQRVHA 390

Query: 142 RDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE 201
           +   E E  E+    E   +A   Q   +  +   EE E   R++   E  E+  +   E
Sbjct: 391 KQRREREEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAE 450

Query: 202 NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHH 261
             G L++  AE+A+ ++  +   +E+ ++    +  L +G ER    RRE          
Sbjct: 451 RQGLLRRERAERAAREDRLRKLQQEQNLKQR--EEGLQEGRERAEQIRRE--------RA 500

Query: 262 QPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307
           Q  A  +Q +E   +RE++E+ + E  R E      T  ++  REG
Sbjct: 501 QRAARAKQRQEGQLQREKRELSRAERARHEALLQGRTRQQRQEREG 546


>gi|148746183 ubiquitin specific protease 35 [Homo sapiens]
          Length = 1018

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 5/83 (6%)

Query: 117 TEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEV--QEQAIRMQGHRQLHQE 174
           T    L +     +EAG   S +E  + EEE   ERT K EV  +E++ R +G R+  +E
Sbjct: 652 TPPTSLYIEGLDSKEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEE 711

Query: 175 EDEEEEKEER---KRGPMETFED 194
            +EEEEK E+   K    E  ED
Sbjct: 712 VEEEEEKVEKETEKEAEQEKEED 734



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 2/70 (2%)

Query: 233 GGDRSLWQGAERG--GGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRD 290
           GG  S  +  ER   G E R +             E  +EKEE  E EE++VE+      
Sbjct: 668 GGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVEKETEKEA 727

Query: 291 ELKKVTETLG 300
           E +K  ++LG
Sbjct: 728 EQEKEEDSLG 737


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 69/279 (24%), Positives = 112/279 (40%), Gaps = 44/279 (15%)

Query: 44  AGSAPSGEASGAEP--PAGDTTAAPLAPRP---------------SKEELTRCLAEVVTE 86
           +GSA +GE S +EP  PA    AAP+ P P                +EE  R     + E
Sbjct: 36  SGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEE 95

Query: 87  VLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEE 146
            L   +++R    A L KEL   E H     E+        ++Q+A   R  +E R E +
Sbjct: 96  KLETLRLKRAEDKAKL-KEL---EKHK-IQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 150

Query: 147 EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDL 206
           E  A    +  ++E A           +++  EE+ E  +  +E               L
Sbjct: 151 E--ALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEA--------------L 194

Query: 207 QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAE 266
           ++RV E  +D E  + + EEKG         L Q  E+    R +D           E +
Sbjct: 195 KERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNA--RLKDALVRMRDLSSSEKQ 252

Query: 267 PRQEKEEASEREEKEVE----QLEHLRDELKKVTETLGE 301
              + ++  E++ +E+E    Q E L++EL +   T+ E
Sbjct: 253 EHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 291


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 69/279 (24%), Positives = 112/279 (40%), Gaps = 44/279 (15%)

Query: 44  AGSAPSGEASGAEP--PAGDTTAAPLAPRP---------------SKEELTRCLAEVVTE 86
           +GSA +GE S +EP  PA    AAP+ P P                +EE  R     + E
Sbjct: 150 SGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEE 209

Query: 87  VLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEE 146
            L   +++R    A L KEL   E H     E+        ++Q+A   R  +E R E +
Sbjct: 210 KLETLRLKRAEDKAKL-KEL---EKHK-IQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 264

Query: 147 EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDL 206
           E  A    +  ++E A           +++  EE+ E  +  +E               L
Sbjct: 265 E--ALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEA--------------L 308

Query: 207 QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAE 266
           ++RV E  +D E  + + EEKG         L Q  E+    R +D           E +
Sbjct: 309 KERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNA--RLKDALVRMRDLSSSEKQ 366

Query: 267 PRQEKEEASEREEKEVE----QLEHLRDELKKVTETLGE 301
              + ++  E++ +E+E    Q E L++EL +   T+ E
Sbjct: 367 EHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 405


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 69/279 (24%), Positives = 112/279 (40%), Gaps = 44/279 (15%)

Query: 44  AGSAPSGEASGAEP--PAGDTTAAPLAPRP---------------SKEELTRCLAEVVTE 86
           +GSA +GE S +EP  PA    AAP+ P P                +EE  R     + E
Sbjct: 36  SGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEE 95

Query: 87  VLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEE 146
            L   +++R    A L KEL   E H     E+        ++Q+A   R  +E R E +
Sbjct: 96  KLETLRLKRAEDKAKL-KEL---EKHK-IQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 150

Query: 147 EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDL 206
           E  A    +  ++E A           +++  EE+ E  +  +E               L
Sbjct: 151 E--ALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEA--------------L 194

Query: 207 QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAE 266
           ++RV E  +D E  + + EEKG         L Q  E+    R +D           E +
Sbjct: 195 KERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNA--RLKDALVRMRDLSSSEKQ 252

Query: 267 PRQEKEEASEREEKEVE----QLEHLRDELKKVTETLGE 301
              + ++  E++ +E+E    Q E L++EL +   T+ E
Sbjct: 253 EHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 291


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 69/279 (24%), Positives = 112/279 (40%), Gaps = 44/279 (15%)

Query: 44  AGSAPSGEASGAEP--PAGDTTAAPLAPRP---------------SKEELTRCLAEVVTE 86
           +GSA +GE S +EP  PA    AAP+ P P                +EE  R     + E
Sbjct: 170 SGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEE 229

Query: 87  VLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEE 146
            L   +++R    A L KEL   E H     E+        ++Q+A   R  +E R E +
Sbjct: 230 KLETLRLKRAEDKAKL-KEL---EKHK-IQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 284

Query: 147 EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDL 206
           E  A    +  ++E A           +++  EE+ E  +  +E               L
Sbjct: 285 E--ALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEA--------------L 328

Query: 207 QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAE 266
           ++RV E  +D E  + + EEKG         L Q  E+    R +D           E +
Sbjct: 329 KERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNA--RLKDALVRMRDLSSSEKQ 386

Query: 267 PRQEKEEASEREEKEVE----QLEHLRDELKKVTETLGE 301
              + ++  E++ +E+E    Q E L++EL +   T+ E
Sbjct: 387 EHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 425


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.130    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,833,471
Number of Sequences: 37866
Number of extensions: 863043
Number of successful extensions: 19494
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 406
Number of HSP's successfully gapped in prelim test: 637
Number of HSP's that attempted gapping in prelim test: 8369
Number of HSP's gapped (non-prelim): 5537
length of query: 307
length of database: 18,247,518
effective HSP length: 102
effective length of query: 205
effective length of database: 14,385,186
effective search space: 2948963130
effective search space used: 2948963130
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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