BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|169213941 PREDICTED: similar to mCG2980 [Homo sapiens] (307 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|169213941 PREDICTED: similar to mCG2980 [Homo sapiens] 626 e-180 gi|169214360 PREDICTED: similar to mCG2980 isoform 1 [Homo sapiens] 626 e-180 gi|169213374 PREDICTED: similar to mCG2980 isoform 1 [Homo sapiens] 626 e-180 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 60 2e-09 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 60 2e-09 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 59 4e-09 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 59 4e-09 gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 59 5e-09 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 57 2e-08 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 56 4e-08 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 56 5e-08 gi|148746195 trichohyalin [Homo sapiens] 55 6e-08 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 55 1e-07 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 55 1e-07 gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 52 5e-07 gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 51 1e-06 gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 51 1e-06 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 50 2e-06 gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 50 3e-06 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 50 3e-06 gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 49 6e-06 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 48 1e-05 gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] 48 1e-05 gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] 48 1e-05 gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] 48 1e-05 gi|148746183 ubiquitin specific protease 35 [Homo sapiens] 48 1e-05 gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 47 2e-05 gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 47 2e-05 gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 47 2e-05 gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 47 2e-05 >gi|169213941 PREDICTED: similar to mCG2980 [Homo sapiens] Length = 307 Score = 626 bits (1615), Expect = e-180 Identities = 307/307 (100%), Positives = 307/307 (100%) Query: 1 MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60 MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG Sbjct: 1 MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60 Query: 61 DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120 DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK Sbjct: 61 DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120 Query: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE Sbjct: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180 Query: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ Sbjct: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240 Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG Sbjct: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300 Query: 301 EQLRREG 307 EQLRREG Sbjct: 301 EQLRREG 307 >gi|169214360 PREDICTED: similar to mCG2980 isoform 1 [Homo sapiens] Length = 307 Score = 626 bits (1615), Expect = e-180 Identities = 307/307 (100%), Positives = 307/307 (100%) Query: 1 MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60 MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG Sbjct: 1 MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60 Query: 61 DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120 DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK Sbjct: 61 DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120 Query: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE Sbjct: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180 Query: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ Sbjct: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240 Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG Sbjct: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300 Query: 301 EQLRREG 307 EQLRREG Sbjct: 301 EQLRREG 307 >gi|169213374 PREDICTED: similar to mCG2980 isoform 1 [Homo sapiens] Length = 307 Score = 626 bits (1615), Expect = e-180 Identities = 307/307 (100%), Positives = 307/307 (100%) Query: 1 MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60 MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG Sbjct: 1 MPPRGPASELLLLRLLLLGAGECGTCRVRDLPGAGERGLQWEGAGSAPSGEASGAEPPAG 60 Query: 61 DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120 DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK Sbjct: 61 DTTAAPLAPRPSKEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEK 120 Query: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE Sbjct: 121 GLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE 180 Query: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ Sbjct: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240 Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG Sbjct: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300 Query: 301 EQLRREG 307 EQLRREG Sbjct: 301 EQLRREG 307 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 60.5 bits (145), Expect = 2e-09 Identities = 52/194 (26%), Positives = 88/194 (45%), Gaps = 27/194 (13%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--EEEEKEERK 185 K QE K QE + +EEE + ER K +E+ +R Q + QEE+ E+EEKE ++ Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 490 Query: 186 RGPMETFEDLWQ------------------RHLENGGDLQKRV--AEKASDKETAQFQAE 225 + E E LW+ R E +K++ EK ++E ++ E Sbjct: 491 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550 Query: 226 EKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEV--E 283 EK + ++ +W ER + +E + E R + E REE+E+ E Sbjct: 551 EK---MRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607 Query: 284 QLEHLRDELKKVTE 297 Q E ++++ +K+ E Sbjct: 608 QEEKMQEQEEKMQE 621 Score = 57.4 bits (137), Expect = 2e-08 Identities = 48/201 (23%), Positives = 98/201 (48%), Gaps = 17/201 (8%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 EEK + +++ GKMR +E +E+ + E+ + E++EQ ++ ++L ++E++ Sbjct: 292 EEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQ--EKELREQEKELREQKELREQEEQ 349 Query: 178 EEEKEER---KRGPMETFEDLWQRHLENGGDLQKRVAE---KASDKETAQFQAEEK---G 228 +E+EE+ + M E+ R E + +K++ E K D+E ++ +E+ Sbjct: 350 MQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409 Query: 229 VRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHL 288 + +W+ E+ R E + + E QE+E ERE+K E+ E + Sbjct: 410 EERMREQEKMWEQVEK---MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466 Query: 289 RDE---LKKVTETLGEQLRRE 306 R++ ++K E + EQ +E Sbjct: 467 REQEEKMQKQEENMWEQEEKE 487 Score = 54.3 bits (129), Expect = 1e-07 Identities = 44/189 (23%), Positives = 84/189 (44%), Gaps = 14/189 (7%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE----------DE 177 K QE K QE + EEE + ER K +E+ +R Q + QEE ++ Sbjct: 570 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ 629 Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237 EE+ +E++ E E +W++ E + Q+ +K E + Q +EK + + Sbjct: 630 EEKMQEQEEKMWEQEEKMWEQE-EKMWEQQRLPEQKEKLWEHEKMQEQEK---MQEQEEK 685 Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 +W+ + + ++ + E R+ +++ E EE EQ E ++++ +K+ E Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745 Query: 298 TLGEQLRRE 306 E +E Sbjct: 746 QEEEMWEQE 754 Score = 53.9 bits (128), Expect = 2e-07 Identities = 45/184 (24%), Positives = 88/184 (47%), Gaps = 15/184 (8%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEE-VAERTHKSEVQEQAIRMQGHRQLHQEE- 175 EE+ + + K +E +M QE + +E+EE + E+ K QE+ ++ Q + QEE Sbjct: 587 EEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEK 646 Query: 176 --DEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLG 233 ++EE+ E++R P E E LW+ + + EK ++E + + +E+ Sbjct: 647 MWEQEEKMWEQQRLP-EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ------ 699 Query: 234 GDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELK 293 ++ W + E + + E R+++E+ E+EEK EQ E + ++ + Sbjct: 700 -EKKTWDQEKM---REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755 Query: 294 KVTE 297 K+ E Sbjct: 756 KMWE 759 Score = 53.9 bits (128), Expect = 2e-07 Identities = 46/178 (25%), Positives = 82/178 (46%), Gaps = 11/178 (6%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE---DEEEEKEER 184 K +E MR ++ EEEE + E+ K + QE+ ++ Q QEE ++EE+ E+ Sbjct: 708 KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767 Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEK----GVRVLGGDRSLWQ 240 +R P E E LW+ + EK D+E EEK ++ G + +W Sbjct: 768 QRLP-EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG 826 Query: 241 GAERGGGERREDLPHHHH---HHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKV 295 E+ G+ + + E + + ++E+ E+EEK Q E +R++ +K+ Sbjct: 827 QEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKM 884 Score = 50.8 bits (120), Expect = 1e-06 Identities = 47/184 (25%), Positives = 86/184 (46%), Gaps = 22/184 (11%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED-EEEEKEERKRG 187 +++ K+R +E +EE + E+ K QE+ + Q R QE++ E+EKE R++ Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK 341 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 + E+ Q E + + EK ++E ++ EE+ LW+ E+ Sbjct: 342 ELREQEEQMQEQEEKMWEQE----EKMREQEEKMWRQEER----------LWE-QEKQMR 386 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELK-----KVTETLGEQ 302 E+ + + + + E +EKEE +EK EQ+E +R+E K K T E+ Sbjct: 387 EQEQKMRDQEERMWEQD-ERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445 Query: 303 LRRE 306 ++ E Sbjct: 446 MQEE 449 Score = 50.8 bits (120), Expect = 1e-06 Identities = 42/167 (25%), Positives = 78/167 (46%), Gaps = 7/167 (4%) Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPM 189 ++ KMR +E +EE + E+ + QEQ +R Q R Q+E EKEER R Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE-RLREKEERMREQE 417 Query: 190 ETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGER 249 + +E + + E Q++ +K + + E+ ++ + ++ + E+ ++ Sbjct: 418 KMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK-MQKQ 476 Query: 250 REDLPHHHHHHHQPEAEPRQ-----EKEEASEREEKEVEQLEHLRDE 291 E++ Q + P Q E+E+ E+EEK EQ E +RD+ Sbjct: 477 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 523 Score = 50.1 bits (118), Expect = 3e-06 Identities = 45/179 (25%), Positives = 83/179 (46%), Gaps = 13/179 (7%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEE-----EKEE 183 ++E MR +E ++EE + E+ K E Q+Q + Q + QE+ +E+ E+EE Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEK-EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518 Query: 184 RKRGPMETF---EDLW-QRHLENGGDLQKRVAEKASDKETAQFQAEEK-GVRVLGGDRSL 238 + R E + + +W Q + D EK D+E + EE+ + ++ Sbjct: 519 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKT 578 Query: 239 WQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 W E+ E R + + E R+++E+ E+EEK EQ E + ++ +K+ E Sbjct: 579 WDQEEKMREEER--MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQE 635 Score = 47.4 bits (111), Expect = 2e-05 Identities = 45/171 (26%), Positives = 82/171 (47%), Gaps = 13/171 (7%) Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE--KEERKRGPMET 191 KMR ++ E+EE++ ++ K QE+ + + Q + D+EE+ +EER R + Sbjct: 538 KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKK 597 Query: 192 FEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERRE 251 + + E +Q++ EK ++E ++ EEK + + +W+ E+ E+ E Sbjct: 598 MREEEEMMREQEEKMQEQ-EEKMQEQEEKMWEQEEK---MQEQEEKMWEQEEK-MWEQEE 652 Query: 252 DLPHHHHHHHQPEA----EPRQEKEEASEREEK--EVEQLEHLRDELKKVT 296 + Q E E QE+E+ E+EEK E E++E E +K T Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703 Score = 47.4 bits (111), Expect = 2e-05 Identities = 38/178 (21%), Positives = 87/178 (48%), Gaps = 14/178 (7%) Query: 128 KKQEAGKMRSSQEVRDEE------EEEVAERTHKSEVQ--EQAIRMQGHRQLHQEEDEEE 179 ++QE +++RD+E EE + ++T + E + +Q +M+ ++ + E + Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599 Query: 180 EKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLW 239 E+EE R E ++ ++ E + ++ EK ++E ++ EEK + + +W Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQ-EEKMQEQEEKMWEQEEK---MWEQEEKMW 655 Query: 240 QGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 + ++ E++E L H Q + + ++EK E+ EK+ ++ E + +K+ E Sbjct: 656 E--QQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE 711 Score = 47.0 bits (110), Expect = 2e-05 Identities = 46/203 (22%), Positives = 94/203 (46%), Gaps = 26/203 (12%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAI-------------- 163 EEK + +++ KM +E E+EE++ E+ K QE+ + Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW 668 Query: 164 ---RMQGHRQLHQEEDE--EEEKEERKRGPME--TFEDLWQRHLENGGDLQKRVAEKASD 216 +MQ ++ ++E++ E+EK E+K E T++ R E+ + +K++ E+ Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728 Query: 217 KETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEA----EPRQEKE 272 + + +E+ ++ + +W+ E+ E+ E + Q E E QE+E Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEK-MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE 787 Query: 273 EASEREEKEVEQLEHLRDELKKV 295 + E+EEK +Q E +R + +K+ Sbjct: 788 KIWEQEEKMRDQEEKMRGQEEKM 810 Score = 43.9 bits (102), Expect = 2e-04 Identities = 41/180 (22%), Positives = 81/180 (45%), Gaps = 32/180 (17%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 E+K L K QE + QE + ++EE+ + K QE ++ ++ED+ Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE---------KMREQEDQ 545 Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237 E+EE+ R + + +W D ++R+ +K ++E + EEK Sbjct: 546 MWEQEEKMR---DQEQKMW--------DQEERMEKKTQEQEKKTWDQEEK---------- 584 Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 E ER + + + E + ++++E+ E+EEK EQ E ++++ +K+ E Sbjct: 585 --MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE 642 Score = 36.6 bits (83), Expect = 0.029 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 9/119 (7%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED- 176 E+K L K QE K+ +E ++EE++ + K QE+ +R Q + QEE Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831 Query: 177 -EEEEK----EERKRGPMETFEDLWQRHLENGGDLQKRV---AEKASDKETAQFQAEEK 227 +EEK EE+ G E E+ Q E + ++++ EK ++E EEK Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890 Score = 35.8 bits (81), Expect = 0.049 Identities = 38/189 (20%), Positives = 93/189 (49%), Gaps = 18/189 (9%) Query: 129 KQEAGKMRSSQEVRDE-----EEEEVAERTHKSEVQEQAIRMQGH-RQLHQE-EDEEEEK 181 +++ +MR +++ ++ EE+++ E+ K+ QE+ ++ + R+ ++ +EEE Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466 Query: 182 EERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQG 241 E++ + E++W++ E Q+R+ E+ +K Q + +E+ ++ + + Sbjct: 467 REQEEKMQKQEENMWEQ--EEKEWQQQRLPEQ-KEKLWEQEKMQEQEEKIWEQEEKIRDQ 523 Query: 242 AERGGGE----RREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 E G E R+E + + E + R ++++ ++EE+ +E E +K T Sbjct: 524 EEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER----MEKKTQEQEKKTW 579 Query: 298 TLGEQLRRE 306 E++R E Sbjct: 580 DQEEKMREE 588 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 60.1 bits (144), Expect = 2e-09 Identities = 55/216 (25%), Positives = 94/216 (43%), Gaps = 16/216 (7%) Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161 L KEL A EE L +Q+ KM +E E EE++ E+ K QE+ Sbjct: 258 LGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE 316 Query: 162 AIRMQGHRQLHQEED---------EEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAE 212 +R Q +EE E+EEK M E + ++ + + + R E Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376 Query: 213 KASDKETAQFQAEEK---GVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQ 269 K ++E ++ EEK + + Q E GE+ E + + E + R+ Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436 Query: 270 EKEEASEREEKEVEQLEHLRDE---LKKVTETLGEQ 302 ++E+ E+E+K EQ E +R++ +++ E +GEQ Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472 Score = 58.2 bits (139), Expect = 9e-09 Identities = 52/187 (27%), Positives = 90/187 (48%), Gaps = 10/187 (5%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--EEEEKEERK 185 K+QE K+R QE R E+E ++ + K QE+ IR Q QEE E+EEK + Sbjct: 365 KRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQ 423 Query: 186 RGPMETFEDLWQRHLENGGDLQKRVAEKAS----DKETAQFQAEEKGVRV--LGGDRSLW 239 M+ E+ +R E + +K++ E+ +E Q Q E+ G + + + Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483 Query: 240 QGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETL 299 Q E + E + + E + R+++E E+EEK EQ E + ++ +K+ E Sbjct: 484 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ- 542 Query: 300 GEQLRRE 306 E++RR+ Sbjct: 543 EEKMRRQ 549 Score = 57.0 bits (136), Expect = 2e-08 Identities = 49/177 (27%), Positives = 85/177 (48%), Gaps = 15/177 (8%) Query: 128 KKQEAGKMRSSQEVRDEEE-----EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE 182 K E K+R +E R EEE E+ E+ K QE+ IR Q + QEE +E++E Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411 Query: 183 ERKRGPMETFEDLWQR--HLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240 K G E E +W++ ++ + +R EK ++E + EEK + + Q Sbjct: 412 --KMGEQE--EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK----IREQEEMMQ 463 Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 E GE+ + + E + R+++E+ E+E+K EQ E +R++ + + E Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520 Score = 56.2 bits (134), Expect = 4e-08 Identities = 47/189 (24%), Positives = 93/189 (49%), Gaps = 23/189 (12%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 EEK + ++ KMR +E+ E+EE++ E K QE+ IR Q ++ +E+ Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIR 373 Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237 E+EK + + M W R E + ++++ E+ +E Q Q E+ G + + Sbjct: 374 EQEKRQEQEAKM------W-RQEEKIREQEEKIREQ---EEMMQEQEEKMGEQ----EEK 419 Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 +W E+ E++ + E + R+++++ E+EEK EQ E ++++ +K+ E Sbjct: 420 MW--------EQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGE 471 Query: 298 TLGEQLRRE 306 G+ +E Sbjct: 472 QEGKMCEQE 480 Score = 52.4 bits (124), Expect = 5e-07 Identities = 42/180 (23%), Positives = 85/180 (47%), Gaps = 20/180 (11%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 EEK + +++ KM +E E+EEE+ E+ K QE+ IR Q +++ ++E++ Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ-EKKIREQEEK 454 Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237 E+EE + E + + E +Q++ E+ ++ + + +EK +R Sbjct: 455 IREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ--EEKMRRQEEKIREQEKKIR------- 505 Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 E+ E + + E + +++E+ E+EEK EQ E +R + +K+ E Sbjct: 506 ----------EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMRE 555 Score = 42.4 bits (98), Expect = 5e-04 Identities = 39/183 (21%), Positives = 81/183 (44%), Gaps = 19/183 (10%) Query: 104 KELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAI 163 +E+ + EEK + +++ KMR +E E+E+++ E+ K QE+ + Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462 Query: 164 RMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRV---AEKASDKETA 220 + Q ++ E+E K + M+ E+ +R E + +K++ EK ++E Sbjct: 463 QEQ-----EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517 Query: 221 QFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEK 280 + EEK +W+ E+ E+ E + + E + R+++ ++EEK Sbjct: 518 MQEQEEK----------MWEQEEK-MCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566 Query: 281 EVE 283 E Sbjct: 567 MQE 569 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 59.3 bits (142), Expect = 4e-09 Identities = 39/182 (21%), Positives = 91/182 (50%), Gaps = 5/182 (2%) Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED-EEEEKEERKRGP 188 ++ +MR +E E+EE+V ++ + + QE+ +R Q + QEE E+E++ K+ Sbjct: 224 EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKE 283 Query: 189 METFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGE 248 E+ E + ++++ E+ + Q E+ ++ + +W+ E+ E Sbjct: 284 QTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQ-MWE 342 Query: 249 RREDLPHHHHHHHQPEAEPRQEKEEASEREE---KEVEQLEHLRDELKKVTETLGEQLRR 305 ++E + + E + ++++E+ ++EE K+ EQ+ ++++K E +GEQ + Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ 402 Query: 306 EG 307 G Sbjct: 403 MG 404 Score = 55.1 bits (131), Expect = 8e-08 Identities = 42/195 (21%), Positives = 90/195 (46%), Gaps = 7/195 (3%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRM----QGHRQLHQ 173 E+ G +KQE + +++R +EE+ + E +EQ ++ + Q + Sbjct: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE 293 Query: 174 EEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEE--KGVRV 231 +E++ E+EE+ R E + ++ E + K+ + KE Q E+ K Sbjct: 294 QEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQ 353 Query: 232 LGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE 291 +G Q E ++ E + + E + R+++E+ E++E+ EQ E +R++ Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ 413 Query: 292 LKKVTETLGEQLRRE 306 +++ E EQ+R++ Sbjct: 414 EEQMGEQ-KEQMRKQ 427 Score = 50.4 bits (119), Expect = 2e-06 Identities = 42/178 (23%), Positives = 85/178 (47%), Gaps = 21/178 (11%) Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEE--EEKEERKRG 187 ++ G+M +E E+EE++ ++ + QE+ +R Q + QEE + EE+ +++ Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEE 255 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 M E+ + E Q R E+ K+ Q + EE+ G++ E Sbjct: 256 QMRKQEEQMREQEE-----QMREQEEQMLKQKEQTEQEEQ-----TGEQ------EEQMR 299 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHL---RDELKKVTETLGEQ 302 E+ E + + E + R+++E+ ++EE+ EQ E + ++++ K E +GEQ Sbjct: 300 EQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQ 357 Score = 46.2 bits (108), Expect = 4e-05 Identities = 37/182 (20%), Positives = 86/182 (47%), Gaps = 7/182 (3%) Query: 125 GDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184 G ++QE G++R + E+E +V E+ + QE +R Q Q+ ++E + E+E + Sbjct: 108 GQVREQE-GQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQ 165 Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAER 244 R + + E G ++++ + + Q E+ +G Q E Sbjct: 166 VREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ-----MGEQEEQMQKQEE 220 Query: 245 GGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLR 304 GE+ E + + E + ++++E+ ++EE+ +Q E +R++ +++ E + L+ Sbjct: 221 QMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280 Query: 305 RE 306 ++ Sbjct: 281 QK 282 Score = 42.4 bits (98), Expect = 5e-04 Identities = 43/191 (22%), Positives = 85/191 (44%), Gaps = 16/191 (8%) Query: 125 GDFKKQEAGKMRSSQEVRDEE----EEEVAERTHKSEVQEQAIRMQGHR-QLHQEEDEEE 179 G ++QE +VR++E E+E R + +V+EQ +++ Q+ ++E + Sbjct: 52 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 111 Query: 180 EKEERKRGPMETFEDLWQRHLENGGDL-----QKRVAEKASDKETAQFQAEEKGVRVLGG 234 E+E + R + + E G + Q R E ++ Q + +E VR G Sbjct: 112 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 171 Query: 235 DRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREE---KEVEQLEHLRDE 291 +G R E+ + + E + +++E+ E+EE K+ EQ+ ++ Sbjct: 172 QVREQEGQVR---EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQ 228 Query: 292 LKKVTETLGEQ 302 ++K E +GEQ Sbjct: 229 MRKQEEQMGEQ 239 Score = 39.3 bits (90), Expect = 0.004 Identities = 35/164 (21%), Positives = 72/164 (43%), Gaps = 32/164 (19%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHR------QLHQEEDEEEEKE 182 +++ +MR +E E+EE++ E+ + QE+ + Q + Q+ ++E++ E+E Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE 358 Query: 183 ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242 E+ + E Q R E+ K+ Q + +E+ +R Sbjct: 359 EQMQKQEE----------------QVRKQEEQMRKQEEQMRKQEEQMR----------KQ 392 Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286 E GE++E + + E + ++KE+ ++EE EQ E Sbjct: 393 EEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436 Score = 35.0 bits (79), Expect = 0.084 Identities = 43/181 (23%), Positives = 78/181 (43%), Gaps = 21/181 (11%) Query: 128 KKQEAGKMRSSQEVRDEEEE-EVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKR 186 +K E K+ QE + E+E +V E+ + QE +R Q Q+ ++E + E+E + R Sbjct: 39 RKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQVR 97 Query: 187 GPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG 246 E G Q R E ++ Q + +E VR G +G R Sbjct: 98 --------------EQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR-- 139 Query: 247 GERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 E+ + + E + R+++ + E+E + EQ +R++ +V E G+ +E Sbjct: 140 -EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQE 198 Query: 307 G 307 G Sbjct: 199 G 199 Score = 33.5 bits (75), Expect = 0.24 Identities = 40/185 (21%), Positives = 77/185 (41%), Gaps = 10/185 (5%) Query: 126 DFKKQEAGKMRSSQEVRDEEEE---EVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE 182 + K++ A Q V E+ E + E K E + + +G Q+ ++E + E+E Sbjct: 8 ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEG--QVREQEGQVREQE 65 Query: 183 ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242 + R + + E G Q R E ++ Q + +E VR G +G Sbjct: 66 GQVREQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 123 Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302 R E+ + + E + R+++ + E+E + EQ +R++ +V E G+ Sbjct: 124 VR---EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180 Query: 303 LRREG 307 +EG Sbjct: 181 REQEG 185 Score = 32.7 bits (73), Expect = 0.41 Identities = 18/55 (32%), Positives = 31/55 (56%), Gaps = 1/55 (1%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE 182 +KQE +MR +E E++E++ E+ + QE+ + Q + QEE E+KE Sbjct: 383 RKQEE-QMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436 Score = 30.0 bits (66), Expect = 2.7 Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 3/60 (5%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 +KQE +MR +E ++EE++ E+ K ++ EQ +M+ + E+ E+ K+E G Sbjct: 376 RKQEE-QMRKQEEQMRKQEEQMGEQ--KEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMG 432 Score = 29.3 bits (64), Expect = 4.6 Identities = 39/174 (22%), Positives = 72/174 (41%), Gaps = 14/174 (8%) Query: 136 RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPME--TFE 193 R + E E+ E+ E E ++ I QLH +E + + + ++ P E E Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEI------QLHIKELKRKLETDKIPLPQEGQVRE 56 Query: 194 DLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDL 253 Q + G Q R E ++ Q + +E VR G +G R E+ + Sbjct: 57 QEGQVREQEG---QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR---EQEGQV 110 Query: 254 PHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307 + E + R+++ + E+E + EQ +R++ +V E G+ +EG Sbjct: 111 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 164 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 59.3 bits (142), Expect = 4e-09 Identities = 43/168 (25%), Positives = 82/168 (48%), Gaps = 18/168 (10%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 K +E +MR ++ EEEE + E+ K + QE+ +R Q + QEE +E++E+ Sbjct: 555 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKM--- 611 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 E E +W++ E +K ++E ++ EEK + + +W+ E+ Sbjct: 612 -WEQEEKMWEQEEE----------DKMQEQEEMMWEQEEK---MQEQEEKMWEQEEK-MR 656 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKV 295 E+ E + E + R+++E+ +EEK EQ E +R + +K+ Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704 Score = 55.5 bits (132), Expect = 6e-08 Identities = 46/189 (24%), Positives = 91/189 (48%), Gaps = 14/189 (7%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED-EEEEKEERKRG 187 +++ K+R +E +EE + E+ K QE+ +R Q R QE++ E+EKE R++ Sbjct: 244 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQK 303 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASD--KETAQFQAEEKGVR-----VLGGDRSLWQ 240 + E+ Q E + ++++ E+ ++ + +EK +R + + +W+ Sbjct: 304 KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWE 363 Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE---LKKVTE 297 ER R ++ + E QE+E ERE+K E+ E +R++ ++K E Sbjct: 364 QDER---LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420 Query: 298 TLGEQLRRE 306 + EQ +E Sbjct: 421 NMWEQEEKE 429 Score = 53.9 bits (128), Expect = 2e-07 Identities = 46/190 (24%), Positives = 88/190 (46%), Gaps = 28/190 (14%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHR------QL 171 +EK L + + +E K+R +E E+EE++ E+ K QE+ + Q R Q+ Sbjct: 288 QEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQM 347 Query: 172 HQEEDEEEEKEER----------KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQ 221 ++E + ++EER K M E +W++ E ++R+ E+ + Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ--EEKMQEEERIREREKKMREEE 405 Query: 222 FQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKE 281 E+ ++ + ++W+ E+ ++R LP + E E+E+ E+EEK Sbjct: 406 ETMREQEEKMQKQEENMWEQEEKEWQQQR--LPE--------QKEKLWEQEKMQEQEEKI 455 Query: 282 VEQLEHLRDE 291 EQ E +RD+ Sbjct: 456 WEQEEKIRDQ 465 Score = 52.0 bits (123), Expect = 7e-07 Identities = 45/166 (27%), Positives = 78/166 (46%), Gaps = 18/166 (10%) Query: 139 QEVRDEEEEEVAERTHKSEVQE----QAIRMQGHRQLHQEEDEEEEKEERKRGPMETFED 194 QE E+EE++ E+ K QE Q +M ++ ++ED+ E+EE+ R + D Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 504 Query: 195 LWQRHLENGGDLQKRVAEKASDKETAQFQAEEK---GVRVLGGDRSLWQGAERGGGERRE 251 +R E D + R E+ ++ +Q EEK + ++ W E+ E R Sbjct: 505 QEERMWEQ--DERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER- 561 Query: 252 DLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 + E + R+E+E E+EEK EQ E +R++ +K+ E Sbjct: 562 --------MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE 599 Score = 51.2 bits (121), Expect = 1e-06 Identities = 45/169 (26%), Positives = 78/169 (46%), Gaps = 41/169 (24%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 K QE K QE + EEE + ER K +E+ +R ++E++ +E+EE+ R Sbjct: 541 KTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR--------EQEEKMQEQEEKMR- 591 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 E E +W++ EK ++E ++ EEK +W+ E Sbjct: 592 --EQEEKMWEQE------------EKMQEQEEKMWEQEEK----------MWEQEEEDKM 627 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEAS-EREEKEVEQLEHLRDELKKV 295 + +E++ + E QE+EE E+EEK EQ E +R++ +K+ Sbjct: 628 QEQEEMMWE-------QEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669 Score = 51.2 bits (121), Expect = 1e-06 Identities = 47/194 (24%), Positives = 91/194 (46%), Gaps = 9/194 (4%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEE-VAERTHKSEVQEQAIRMQGHRQLHQEED 176 EE+ + + K +E +M QE + +E+EE + E+ K QE+ ++ Q + QEE Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617 Query: 177 EEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDR 236 E++EE K E E +W++ E + ++++ E+ + + E+ ++ G + Sbjct: 618 MWEQEEEDKMQEQE--EMMWEQE-EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674 Query: 237 SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQE-----KEEASEREEKEVEQLEHLRDE 291 + + E+ G+ + Q E QE +EE +E+ E+ E +RD+ Sbjct: 675 KMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQ 734 Query: 292 LKKVTETLGEQLRR 305 +K+ E L E R Sbjct: 735 KEKMQERLPEHEER 748 Score = 50.8 bits (120), Expect = 1e-06 Identities = 38/176 (21%), Positives = 82/176 (46%), Gaps = 9/176 (5%) Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPM 189 ++ KMR ++ ++EE + E+ + +E+ +R Q + QEE EEK+ +++ Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQQEEKMREEKKTQEQEKK 548 Query: 190 ETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGER 249 ++ R E + +K++ E+ + + +E+ ++ + +W+ E+ + Sbjct: 549 TWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE 608 Query: 250 REDLPHHHHHHHQPEAEPRQEKEE--------ASEREEKEVEQLEHLRDELKKVTE 297 + Q E + QE+EE E+EEK EQ E +R++ +K+ E Sbjct: 609 EKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664 Score = 49.7 bits (117), Expect = 3e-06 Identities = 36/181 (19%), Positives = 88/181 (48%), Gaps = 8/181 (4%) Query: 126 DFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE--- 182 + +++ KM+ +E E+EE++ E+ K + QE+ + Q + QEE+++ +++ Sbjct: 574 EMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEM 633 Query: 183 --ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240 E++ E E +W++ E + ++++ E+ + + + E+ ++ G + + + Sbjct: 634 MWEQEEKMQEQEEKMWEQE-EKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692 Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300 E+ G+ E+ + E +EE E+EE+ +Q E +++ L + E Sbjct: 693 QEEKMRGQ--EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCS 750 Query: 301 E 301 E Sbjct: 751 E 751 Score = 46.6 bits (109), Expect = 3e-05 Identities = 40/161 (24%), Positives = 75/161 (46%), Gaps = 16/161 (9%) Query: 139 QEVRDEEEEEVAERTHKSEVQEQAIRMQGH-RQLHQEEDEEEEKEERKRGPMETFEDLWQ 197 QE + EE++ E+ K+ QE+ +R + R+ ++ EEEE + M+ E+ + Sbjct: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591 Query: 198 RHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHH 257 E + + EK ++E ++ EEK +W+ E + +E++ Sbjct: 592 EQEEKMWEQE----EKMQEQEEKMWEQEEK----------MWEQEEEDKMQEQEEMMWEQ 637 Query: 258 HHHHQPEAEPRQEKEE-ASEREEKEVEQLEHLRDELKKVTE 297 Q + E E+EE E+EEK EQ E ++ + +K+ E Sbjct: 638 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRE 678 Score = 46.2 bits (108), Expect = 4e-05 Identities = 38/159 (23%), Positives = 79/159 (49%), Gaps = 14/159 (8%) Query: 139 QEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQR 198 QE +EEE+ E+ K QE+ + Q R L ++E + E+EE+ R + + + Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEER-LREQEGKMREQEEKMRRQEKRLREQEKE 291 Query: 199 HLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHH 258 E +L+++ +K ++E + EEK +W+ E+ E+ E + Sbjct: 292 LREQEKELREQ--KKLREQEEQMQEQEEK----------MWEQEEK-MREQEEKMWRQEE 338 Query: 259 HHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 + E + R+++++ ++EE+ EQ E LR++ +++ E Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE 377 Score = 44.7 bits (104), Expect = 1e-04 Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 21/150 (14%) Query: 127 FKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKR 186 ++++E KM+ +E+ E+EE++ E+ K QE+ +R ++E++ E+EE+ + Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR--------EQEEKMREQEEKMQ 670 Query: 187 GPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG 246 G E + + ++ + + EK +E + EEK + G + +W E Sbjct: 671 GQEEKMRE-QEEKMQGQEEKMREQEEKMRGQEEKMWGQEEK---MWGQEEKMWGQEEMRE 726 Query: 247 GERR---------EDLPHHHHHHHQPEAEP 267 E R E LP H +P P Sbjct: 727 KEERIRDQKEKMQERLPEHEERCSEPCLPP 756 >gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] Length = 238 Score = 58.9 bits (141), Expect = 5e-09 Identities = 44/174 (25%), Positives = 85/174 (48%), Gaps = 17/174 (9%) Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKE---ERKR 186 +E +MR ++ EEEE + E+ K + QE+ +R Q + QEE +E++E E++ Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 Query: 187 GPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG 246 E E +W+ Q+R+ E+ + EK R+ ++ +WQ E+ Sbjct: 62 KMWEQEEKMWE---------QQRLPEQKEKMWEQDERLREKEERM--REQKMWQQVEKMR 110 Query: 247 GERR---EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 +++ E + + E +++E+ E+EEK EQ E +R++ +K+ E Sbjct: 111 EKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 164 Score = 52.4 bits (124), Expect = 5e-07 Identities = 48/185 (25%), Positives = 90/185 (48%), Gaps = 21/185 (11%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEE-VAERTHKSEVQEQAIRMQGHRQLHQEE- 175 EE+ + + K +E +M QE + +E+EE + E+ K QE+ ++ Q + QEE Sbjct: 3 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 62 Query: 176 --DEEEEKEERKRGPMETFEDLWQ-----RHLENGGDLQK---RVAEKASDKETAQFQAE 225 ++EE+ E++R P E E +W+ R E QK +V + K+T + + + Sbjct: 63 MWEQEEKMWEQQRLP-EQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 Query: 226 EKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQL 285 E+ ++ + +W E+ E + + E + R+++E+ E+EEK Q Sbjct: 122 EQEEKMQEQEEMMW--------EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQE 173 Query: 286 EHLRD 290 E +RD Sbjct: 174 EKMRD 178 Score = 45.8 bits (107), Expect = 5e-05 Identities = 39/158 (24%), Positives = 74/158 (46%), Gaps = 37/158 (23%) Query: 145 EEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGG 204 EEE + ER K +E+ +R ++E++ +E+EE+ R E E +W++ Sbjct: 3 EEERMREREKKMREEEEMMR--------EQEEKMQEQEEKMR---EQEEKMWEQE----- 46 Query: 205 DLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPE 264 EK ++E ++ EEK +W+ E+ ++R LP + + Sbjct: 47 -------EKMQEQEEKMWEQEEK----------MWEQEEKMWEQQR--LPEQKEKMWEQD 87 Query: 265 AEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302 R+++E RE+K +Q+E +R++ K E + EQ Sbjct: 88 ERLREKEERM--REQKMWQQVEKMREKKKTQEEKMQEQ 123 Score = 38.5 bits (88), Expect = 0.008 Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 KK + KM+ +E E+EE + E+ K + QE+ + Q + QEE E+ EE+ +G Sbjct: 113 KKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ-EEKMQG 171 Query: 188 PMETFEDL 195 E D+ Sbjct: 172 QEEKMRDV 179 Score = 30.8 bits (68), Expect = 1.6 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 1/60 (1%) Query: 117 TEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEE-VAERTHKSEVQEQAIRMQGHRQLHQEE 175 T+E+ + + K QE +M QE + +E+EE + E+ K QE+ +R Q + QEE Sbjct: 115 TQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 174 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 57.4 bits (137), Expect = 2e-08 Identities = 45/180 (25%), Positives = 89/180 (49%), Gaps = 14/180 (7%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 K+QE K+R QE R E+E ++ + K QE+ IR Q + QEE E+++ R+ Sbjct: 459 KRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE 517 Query: 188 PMETFEDLWQ-----RHLENGGDLQKRV---AEKASDKETAQFQAEEK----GVRVLGGD 235 + E++W+ R E ++++ EK +E ++ EEK ++ + Sbjct: 518 KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577 Query: 236 RSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKV 295 +W+ E+ E+ E + + E ++++E+ E+EEK EQ E ++++ +K+ Sbjct: 578 EKVWRQEEK-IREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636 Score = 55.1 bits (131), Expect = 8e-08 Identities = 39/170 (22%), Positives = 87/170 (51%), Gaps = 18/170 (10%) Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFE 193 KM +++R++EE+ R + +++EQ R + ++ ++E++ E+EE+ R E E Sbjct: 446 KMHEQEKIREQEEK----RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR---EQEE 498 Query: 194 DLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGE----- 248 +W++ E Q+++ E+ +E + +E+ +R +W+ E+ + Sbjct: 499 KMWRQ--EEKIHEQEKIREEEKRQEQEEMWRQEEKIR---EQEEIWRQKEKIHEQEEKIR 553 Query: 249 -RREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 + E + H E + R+++E+ +EEK EQ E +R++ +K+ E Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE 603 Score = 53.9 bits (128), Expect = 2e-07 Identities = 52/203 (25%), Positives = 92/203 (45%), Gaps = 24/203 (11%) Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161 L KEL A EE L +Q+ KM +E E EE++ E+ K QE+ Sbjct: 331 LGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 389 Query: 162 AIRMQGHRQLHQEED--EEEEKEERKRGPMETFED--------LWQRHLENGGDLQKRVA 211 IR Q + QEE E+EEK R+ M E+ +W++ E +L++++ Sbjct: 390 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKIRELEEKMH 448 Query: 212 EKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEK 271 E+ +E + + EE+ +R E+ + +E + + E +E+ Sbjct: 449 EQEKIREQEEKRQEEEKIR------------EQEKRQEQEAKMWRQEEKIREQEEKIREQ 496 Query: 272 EEASEREEKEVEQLEHLRDELKK 294 EE R+E+++ + E +R+E K+ Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKR 519 Score = 53.5 bits (127), Expect = 2e-07 Identities = 44/170 (25%), Positives = 80/170 (47%), Gaps = 21/170 (12%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 K+QE +M QE + E+EE+ + K QE+ IR Q + QEE +++E+ + Sbjct: 518 KRQEQEEMWR-QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR-- 574 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 E E +W++ EK ++E + EEK + + Q E G Sbjct: 575 --EQEEKVWRQE------------EKIREQEEKIREQEEK----IREQEEMTQEQEEKMG 616 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 E+ E + + E + R+++E+ E+E+K EQ E +R++ + + E Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666 Score = 44.3 bits (103), Expect = 1e-04 Identities = 36/158 (22%), Positives = 71/158 (44%), Gaps = 26/158 (16%) Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFE 193 K+R +E E+EE++ E+ ++ QE+ + Q + QEE +E++E+ +R + E Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE 645 Query: 194 DLWQRHLENGGDLQKRV---AEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250 +K++ EK ++E + EEK +W+ E+ E+ Sbjct: 646 Q------------EKKIREQEEKIREQEEMMQEQEEK----------MWEQEEK-MCEQE 682 Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHL 288 E + + E + +++ ++EEK E EHL Sbjct: 683 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720 Score = 42.4 bits (98), Expect = 5e-04 Identities = 32/133 (24%), Positives = 63/133 (47%), Gaps = 10/133 (7%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--EEEEKEERKR 186 +++ K+R +E+ E+EE++ E+ K QE+ ++ Q + QEE E+E+K + Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE 654 Query: 187 GPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG 246 + E++ Q E + + EK ++E + EEK R + +W+ R Sbjct: 655 EKIREQEEMMQEQEEKMWEQE----EKMCEQEEKMQEQEEKMRR---QEEKMWEQEVR-L 706 Query: 247 GERREDLPHHHHH 259 ++ E + H H Sbjct: 707 RQQEEKMQEHQEH 719 Score = 40.8 bits (94), Expect = 0.002 Identities = 32/119 (26%), Positives = 55/119 (46%), Gaps = 13/119 (10%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 EEK + +++ KM +E E+EE++ E+ K QE+ IR Q + QEE Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657 Query: 178 EEEKEERKRGPMETFEDLWQRH---------LENGGDLQKRVAEKASDKETAQFQAEEK 227 E++E + E E +W++ ++ + +R EK ++E Q EEK Sbjct: 658 REQEEMMQ----EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 712 Score = 39.7 bits (91), Expect = 0.003 Identities = 23/100 (23%), Positives = 50/100 (50%), Gaps = 3/100 (3%) Query: 104 KELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAI 163 +E+ + EEK + +++ KMR +E E+E+++ E+ K QE+ + Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664 Query: 164 RMQGHRQLHQEE---DEEEEKEERKRGPMETFEDLWQRHL 200 + Q + QEE ++EE+ +E++ E +W++ + Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704 Score = 33.5 bits (75), Expect = 0.24 Identities = 22/74 (29%), Positives = 43/74 (58%), Gaps = 4/74 (5%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQ-LHQEEDEEEEKEERKRG 187 +++ K+R +E+ E+EE++ E+ K QE+ +MQ + + ++E++ E+E R R Sbjct: 651 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE--KMQEQEEKMRRQEEKMWEQEVRLRQ 708 Query: 188 PMETFEDLWQRHLE 201 E ++ Q HLE Sbjct: 709 QEEKMQE-HQEHLE 721 Score = 32.3 bits (72), Expect = 0.54 Identities = 21/73 (28%), Positives = 41/73 (56%), Gaps = 7/73 (9%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRD-EEEEEVAERTHKSEVQEQAIRMQGHR------Q 170 +EK + + K +E +M QE + E+EE++ E+ K + QE+ +R Q + + Sbjct: 646 QEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 705 Query: 171 LHQEEDEEEEKEE 183 L Q+E++ +E +E Sbjct: 706 LRQQEEKMQEHQE 718 Score = 30.0 bits (66), Expect = 2.7 Identities = 37/164 (22%), Positives = 73/164 (44%), Gaps = 18/164 (10%) Query: 160 EQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLW--QRHLENGGDLQKRVAEKASDK 217 EQA+ ++ + EE +ER +E + + + E LQ+++ S+K Sbjct: 239 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK 298 Query: 218 ETAQFQAEE-----KGVRVLGGDRSLWQGAERGGGERR----------EDLPHHHHHHHQ 262 Q +E + ++L + L A+ G E + E+ + + Q Sbjct: 299 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 358 Query: 263 PEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 E + +++E+ E EEK EQ E +R++ +K+ E E++RR+ Sbjct: 359 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ-EEKMRRQ 401 Score = 29.6 bits (65), Expect = 3.5 Identities = 37/152 (24%), Positives = 68/152 (44%), Gaps = 17/152 (11%) Query: 157 EVQEQAIRMQGHRQLHQEEDEEEEK--EERKRGPMETFEDLWQRHLENGGDLQKRVAEKA 214 E++E+ ++Q QL + E E + +E KR L Q+ L+ D + + Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338 Query: 215 SDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEA 274 S K AQ + E LW R ++ E + + E + ++++E+ Sbjct: 339 SAKLQAQVEENE-----------LWN---RLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 384 Query: 275 SEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 E+EEK EQ E +R + + + E E++RR+ Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEK-EEKMRRQ 415 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 56.2 bits (134), Expect = 4e-08 Identities = 44/172 (25%), Positives = 85/172 (49%), Gaps = 16/172 (9%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 K+QE K+R QE R E+E ++ + K QE+ IR Q + QEE E+++ R+ Sbjct: 398 KRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEE--KGVRVLGGDRSLWQGAERG 245 + E++W R EK ++E Q E+ + ++ + +W+ E+ Sbjct: 457 KRQEQEEMW------------RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK- 503 Query: 246 GGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 ++ E + + E + R+++E+ E+EEK EQ E ++++ +K+ E Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555 Score = 53.9 bits (128), Expect = 2e-07 Identities = 62/233 (26%), Positives = 98/233 (42%), Gaps = 34/233 (14%) Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161 L KEL A EE L +Q+ KM +E E EE++ E+ K QE+ Sbjct: 270 LGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328 Query: 162 AIRMQGHRQLHQEED--EEEEKEER-------KRGPMETFEDLWQRHLENGGDLQKRVAE 212 IR Q + QEE E+EEK R K M E++ E +L++++ E Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHE 388 Query: 213 KASDKETAQFQAEEKGVRV----LGGDRSLWQGAERGGGERREDLPHH-----------H 257 + +E + + EE+ +R + +W+ E+ E+ E + H Sbjct: 389 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK-IREQEEKIREQEKKMWRQEEKIH 447 Query: 258 HHHHQPEAEPRQEKEEASEREEKEVEQLE--------HLRDELKKVTETLGEQ 302 E E RQE+EE +EEK EQ E H +++++K E + Q Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQ 500 Score = 53.9 bits (128), Expect = 2e-07 Identities = 43/176 (24%), Positives = 87/176 (49%), Gaps = 22/176 (12%) Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--EEEEKEERKRGPMET 191 KM +++R ++EE+V + K QE+ IR Q + QEE E+EEK + + Sbjct: 483 KMHEQEKIR-KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541 Query: 192 FEDLWQRHLENGGDLQKRVAEKAS-DKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250 E++ Q E G+ ++++ E+ ++ + + +E+ +R E++ Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIR-----------------EQK 584 Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 E + + E + R+++E E+EEK EQ E + ++ +K+ E E++RR+ Sbjct: 585 EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ-EEKMRRQ 639 Score = 52.8 bits (125), Expect = 4e-07 Identities = 45/173 (26%), Positives = 89/173 (51%), Gaps = 12/173 (6%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEE--RK 185 ++QEA R +++R E+EE++ E+ K QE+ I Q + +EE++ +E+EE R+ Sbjct: 412 QEQEAKMWRQEEKIR-EQEEKIREQEKKMWRQEEKIHEQ---EKIREEEKRQEQEEMWRQ 467 Query: 186 RGPMETFEDLW-QRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAER 244 + E++W Q+ + + ++ EK +E EEK + + +W+ E+ Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEK---IREQEEKMWRQEEK 524 Query: 245 GGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 E+ E + + E ++++E+ E+EEK EQ E +R + +K+ E Sbjct: 525 -IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ-EKMRRQEEKIRE 575 Score = 48.5 bits (114), Expect = 7e-06 Identities = 39/160 (24%), Positives = 74/160 (46%), Gaps = 28/160 (17%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGP 188 +++ K+R +E+ E+EE++ E+ K + QE+ +R Q + QEE E+KE+ + Sbjct: 533 REQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK-MRRQEEKIREQEEKIREQKEKIR--- 588 Query: 189 METFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGE 248 E E +W++ EK ++E + EEK +W+ E+ E Sbjct: 589 -EQEEKIWEQE------------EKIREQEEMMQEQEEK----------MWEQEEK-MCE 624 Query: 249 RREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHL 288 + E + + E + +++ ++EEK E EHL Sbjct: 625 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664 Score = 47.0 bits (110), Expect = 2e-05 Identities = 47/192 (24%), Positives = 89/192 (46%), Gaps = 20/192 (10%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 EEK + ++ KMR +E+ E+EE++ E K QE+ IR Q ++ +E+ Sbjct: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIR 406 Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRV---AEKASDKETAQFQAEEKGVRVLGG 234 E+EK + + M E+ + E + +K++ EK ++E + + EEK Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE--KIREEEKRQE---- 460 Query: 235 DRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294 +W+ E+ +E++ H E+E+ ++EEK Q E + D+ +K Sbjct: 461 QEEMWRQEEKI--REQEEIWRQKEKMH--------EQEKIRKQEEKVWRQEEKMHDQEEK 510 Query: 295 VTETLGEQLRRE 306 + E + R+E Sbjct: 511 IREQEEKMWRQE 522 Score = 43.9 bits (102), Expect = 2e-04 Identities = 35/102 (34%), Positives = 48/102 (47%), Gaps = 6/102 (5%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE--DEEEEKEERK 185 K QE KMR +E E+EE++ E+ K QE+ I Q + QEE E+EEK + Sbjct: 559 KMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQ 618 Query: 186 RGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEK 227 M E+ Q E +R EK ++E Q EEK Sbjct: 619 EEKMCEQEEKMQEQEEK----MRRQEEKMWEQEVRLRQQEEK 656 Score = 32.7 bits (73), Expect = 0.41 Identities = 22/73 (30%), Positives = 42/73 (57%), Gaps = 4/73 (5%) Query: 130 QEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQ-LHQEEDEEEEKEERKRGP 188 ++ K+R +E+ E+EE++ E+ K QE+ +MQ + + ++E++ E+E R R Sbjct: 596 EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE--KMQEQEEKMRRQEEKMWEQEVRLRQQ 653 Query: 189 METFEDLWQRHLE 201 E ++ Q HLE Sbjct: 654 EEKMQE-HQEHLE 665 Score = 31.6 bits (70), Expect = 0.92 Identities = 20/65 (30%), Positives = 33/65 (50%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 EEK + +++ KM +E E+EE++ E+ K QE+ + Q R QEE Sbjct: 598 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKM 657 Query: 178 EEEKE 182 +E +E Sbjct: 658 QEHQE 662 Score = 30.8 bits (68), Expect = 1.6 Identities = 19/63 (30%), Positives = 36/63 (57%), Gaps = 7/63 (11%) Query: 128 KKQEAGKMRSSQEVRD-EEEEEVAERTHKSEVQEQAIRMQGHR------QLHQEEDEEEE 180 K +E +M QE + E+EE++ E+ K + QE+ +R Q + +L Q+E++ +E Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659 Query: 181 KEE 183 +E Sbjct: 660 HQE 662 Score = 30.0 bits (66), Expect = 2.7 Identities = 37/164 (22%), Positives = 73/164 (44%), Gaps = 18/164 (10%) Query: 160 EQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLW--QRHLENGGDLQKRVAEKASDK 217 EQA+ ++ + EE +ER +E + + + E LQ+++ S+K Sbjct: 178 EQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEK 237 Query: 218 ETAQFQAEE-----KGVRVLGGDRSLWQGAERGGGERR----------EDLPHHHHHHHQ 262 Q +E + ++L + L A+ G E + E+ + + Q Sbjct: 238 SEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQ 297 Query: 263 PEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 E + +++E+ E EEK EQ E +R++ +K+ E E++RR+ Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ-EEKMRRQ 340 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 55.8 bits (133), Expect = 5e-08 Identities = 55/211 (26%), Positives = 94/211 (44%), Gaps = 29/211 (13%) Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161 L KEL A EE L +Q+ KM +E E EE++ E+ K QE+ Sbjct: 270 LGKELQSVSAKLQAQVEENELW-NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328 Query: 162 AIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQ 221 IR Q + QEE E++E+ +R E +W++ EK +E Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQE----EMMWEKE------------EKMRRQEEMM 372 Query: 222 FQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKE 281 ++ EEK R + +W+ E+ R + H + + E RQE+E+ E+E+++ Sbjct: 373 WEKEEKMRR---QEEMMWEKEEK---IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 426 Query: 282 VE------QLEHLRDELKKVTETLGEQLRRE 306 + Q E +R++ +K+ E + R+E Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQE 457 Score = 55.1 bits (131), Expect = 8e-08 Identities = 52/196 (26%), Positives = 95/196 (48%), Gaps = 22/196 (11%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE---DEEEEKEER 184 K+QE K+R QE R E+E ++ + K QE+ IR Q + QEE ++E+ +EE Sbjct: 412 KRQEEEKIRE-QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470 Query: 185 KRGPMETF----------EDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGG 234 KR E E++W R E + ++++ ++ + + E+ ++ Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIW-RQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529 Query: 235 DRSLWQGAERGGGERREDLPHHHHHHHQP---EAEPRQEKEEASEREEKEV-EQLEHLRD 290 + +W+ E+ E+ E H Q E E RQE+E+ R+E+++ EQ E + Sbjct: 530 EEKMWRQEEK-IREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR 588 Query: 291 ELKKVTETLGEQLRRE 306 + +K+ E E+ R+E Sbjct: 589 QEEKIREQ--EEKRQE 602 Score = 55.1 bits (131), Expect = 8e-08 Identities = 44/181 (24%), Positives = 87/181 (48%), Gaps = 22/181 (12%) Query: 128 KKQEAGKMRSSQEVRDEEE------EEVAERTHKSEVQEQAIRMQGHRQLHQEE--DEEE 179 ++QE R +++R++EE E++ E+ K + QE+ + Q + QEE E+E Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625 Query: 180 EKEERKRGPMETFEDLWQRHLENGGDLQKRVA---EKASDKETAQFQAEEKGVRVLGGDR 236 EK + + E++ Q E G+ ++++ EK ++E ++ EEK Sbjct: 626 EKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK--------- 676 Query: 237 SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVT 296 + E+ E+ E + + E + +++E+ E+EEK EQ E +R + +K+ Sbjct: 677 --IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 734 Query: 297 E 297 E Sbjct: 735 E 735 Score = 52.4 bits (124), Expect = 5e-07 Identities = 45/188 (23%), Positives = 91/188 (48%), Gaps = 12/188 (6%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 E++ + + K E ++ +E E+EE++ ++ K QE+ IR Q ++ E Sbjct: 474 EQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQ-----EEKIRE 528 Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237 +EEK R+ + E++W+ + + EK ++E ++ EEK + + Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK---IREQEEK 585 Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE---LKK 294 +W+ E+ E+ E + E + R+++E+ E+EEK EQ E +R++ ++ Sbjct: 586 VWRQEEK-IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQE 644 Query: 295 VTETLGEQ 302 E +GEQ Sbjct: 645 QEEKMGEQ 652 Score = 49.7 bits (117), Expect = 3e-06 Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 30/185 (16%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE-- 175 EEK + ++++ KM +E E+EE++ E+ K QE+ IR Q QEE Sbjct: 590 EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649 Query: 176 DEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRV---AEKASDKETAQFQAEEKGVRVL 232 E+EEK + M+ E+ R E + +K++ EK ++E + EEK Sbjct: 650 GEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK----- 704 Query: 233 GGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDEL 292 +W+ E+ + E + ++++E+ +EEK EQ LR + Sbjct: 705 -----MWEQEEK---------------MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 744 Query: 293 KKVTE 297 +K+ E Sbjct: 745 EKMQE 749 Score = 48.5 bits (114), Expect = 7e-06 Identities = 45/190 (23%), Positives = 93/190 (48%), Gaps = 14/190 (7%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEE---EEVAERTHKSEVQEQAIRMQGHRQLHQE 174 EEK + ++ K+R +E E+E E+ +R + +++EQ R + ++ ++ Sbjct: 376 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435 Query: 175 EDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGG 234 E++ E+EE+ R E + +W R E + +K E+ ++ ++ EEK + Sbjct: 436 EEKIREQEEKIR---EQEKKMW-RQEEKIHEQEKIREEEKRQEQEEMWRQEEK----IHE 487 Query: 235 DRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLR--DEL 292 +W+ E+ E+ E + + E + R+++E+ E+EEK Q E +R +E+ Sbjct: 488 QEEIWRQKEK-MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEM 546 Query: 293 KKVTETLGEQ 302 + E + EQ Sbjct: 547 WREEEKMHEQ 556 Score = 46.2 bits (108), Expect = 4e-05 Identities = 40/172 (23%), Positives = 83/172 (48%), Gaps = 8/172 (4%) Query: 139 QEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEE--RKRGPMETFEDLW 196 +E R E+E+++ + K QE+ + Q + QEE +E++E+ ++ + E+ Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621 Query: 197 QRHLENGGDLQKRVAEKASDKETAQFQAEEKGVR--VLGGDRSLWQGAERGGGERREDLP 254 Q E + ++++ E+ +E Q Q E+ G + + Q E + E + Sbjct: 622 QEQEEKIREQEEKIREQ---EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678 Query: 255 HHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 + E + R+++E E+EEK EQ E + ++ +K+ E E++RR+ Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ-EEKMRRQ 729 Score = 43.1 bits (100), Expect = 3e-04 Identities = 37/168 (22%), Positives = 77/168 (45%), Gaps = 4/168 (2%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGP 188 +++ KMR +E+ E+EE++ + +E+ +R Q + ++E++ +EE Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKMRRQEEMMWEK 389 Query: 189 METFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGE 248 E +L ++ E ++ + +K Q + +E+ ++ + + + E+ + Sbjct: 390 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 449 Query: 249 RREDLPHHHHHHHQP---EAEPRQEKEEASEREEKEVEQLEHLRDELK 293 ++ H Q E E RQE+EE +EEK EQ E R + K Sbjct: 450 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497 Score = 33.9 bits (76), Expect = 0.19 Identities = 24/100 (24%), Positives = 48/100 (48%), Gaps = 10/100 (10%) Query: 104 KELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAI 163 +E G + EEK ++QE R +++R E+E+++ E+ K QE+ + Sbjct: 646 EEKMGEQEEKMCEQEEK------MQEQEETMWRQEEKIR-EQEKKIREQEEKIREQEEMM 698 Query: 164 RMQGHRQLHQEEDEEEEKE---ERKRGPMETFEDLWQRHL 200 + Q + QEE E++E E++ E +W++ + Sbjct: 699 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 55.5 bits (132), Expect = 6e-08 Identities = 55/195 (28%), Positives = 93/195 (47%), Gaps = 15/195 (7%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTH----KSEVQEQAIRMQGHRQLHQ 173 EE+ L D +++ + + R Q+ R + EEE R H K +QEQ ++ +QL Q Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ---LRKEQQLLQ 907 Query: 174 EEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLG 233 EE+EE ++EER++ + E ++ + + ++ + E ++E + Q E+ R Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE---EREKRRRQERERQYR--- 961 Query: 234 GDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELK 293 D+ L Q E+ GE E E E Q++EE REE+E + + + + Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021 Query: 294 KVTETL--GEQLRRE 306 K E EQL RE Sbjct: 1022 KKDELQQEEEQLLRE 1036 Score = 55.1 bits (131), Expect = 8e-08 Identities = 48/203 (23%), Positives = 88/203 (43%), Gaps = 29/203 (14%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRM--QGHRQLHQEEDEEEEKEERKR 186 K E + R Q++R E++E +R + E +E+ + + H + +E++ EE++E+ R Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR 694 Query: 187 GPMETFEDLWQRHLENGGDL-QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245 +++ WQ LE+ D Q +V + +E + + E++ R WQ ER Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERA 754 Query: 246 GGERREDL--------------------------PHHHHHHHQPEAEPRQEKEEASEREE 279 +++E+ P Q AE RQ++E+ EE Sbjct: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEE 814 Query: 280 KEVEQLEHLRDELKKVTETLGEQ 302 +E EQ R E +K + L E+ Sbjct: 815 EEKEQRRRQRREREKELQFLEEE 837 Score = 53.1 bits (126), Expect = 3e-07 Identities = 42/171 (24%), Positives = 76/171 (44%), Gaps = 11/171 (6%) Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAI-RMQGHRQLHQEEDEEEEKEERKRGPMETF 192 ++R Q++R E+EEE E+ H+ E +EQ + R Q R+ + +EE E+ E++R + Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK 477 Query: 193 EDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERRED 252 D + E L++ + ++ Q + E++ R R E E Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ----------EEEER 527 Query: 253 LPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQL 303 L Q E + +E+ +REE++ + E LK+ E +QL Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578 Score = 52.0 bits (123), Expect = 7e-07 Identities = 43/180 (23%), Positives = 84/180 (46%), Gaps = 21/180 (11%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAE--------RTHKSEVQEQAIRMQGHRQLHQEEDEE-- 178 ++E + R + R EEEE + + R + E +EQ ++ + ++L QE E+ Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567 Query: 179 -EEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237 E+EER+ ++ E+ Q+ L+ + ++R+ ++ +E + + EE+ R Sbjct: 568 KREQEERRDQLLKREEERRQQRLKR--EQEERLEQRLKREEVERLEQEER--------RE 617 Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 E ERR+ L + + + R+E++E E+ K E+ E L LK+ E Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE 677 Score = 51.6 bits (122), Expect = 9e-07 Identities = 48/187 (25%), Positives = 93/187 (49%), Gaps = 15/187 (8%) Query: 125 GDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG-HRQLHQEEDEEE---- 179 G +KQ+ + R + ++EEE+E +R +E+ ++ + RQ +E+EE+ Sbjct: 222 GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281 Query: 180 EKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLW 239 E++E +R E E+ Q+ L L+++ E+ +++ + + +E+ + + Sbjct: 282 ERQELRRERQE--EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ---QEERRE 336 Query: 240 QGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETL 299 Q R ERRE + E + R+E+EE ER E+++ + + LR E + E Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEE--ERREQQLRREQQLRREQQLRRE-- 392 Query: 300 GEQLRRE 306 +QLRRE Sbjct: 393 -QQLRRE 398 Score = 51.6 bits (122), Expect = 9e-07 Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 6/183 (3%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHR---QLHQEEDEEEEKEER 184 ++Q+ ++R Q++R ++EEE E+ + Q++ Q R QL +E++E E++ R Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR 352 Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAER 244 + E E +R E Q+ E+ +E Q E+ +R R Q Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRRE 410 Query: 245 GGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTET-LGEQL 303 R + L + E E ++K E RE++ + E RD LK+ ET EQ Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470 Query: 304 RRE 306 RR+ Sbjct: 471 RRK 473 Score = 51.2 bits (121), Expect = 1e-06 Identities = 52/212 (24%), Positives = 87/212 (41%), Gaps = 28/212 (13%) Query: 123 LLGDFKKQEAGKMRSSQEVRDEE--EEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEE-- 178 LLG+ ++++ + R + RD EEE ER + E + + + Q +QL +EE EE Sbjct: 1270 LLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKR 1329 Query: 179 -------------------EEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKET 219 EE+ R++ F + RH E G + + Sbjct: 1330 RRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERE 1389 Query: 220 AQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEP---RQEKEEASE 276 +F EE+ +R ++ L Q +R E + L E E RQE+E Sbjct: 1390 RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFL 1449 Query: 277 REEKEVEQLEH--LRDELKKVTETLGEQLRRE 306 EE+++ Q H R+E + + E +QL R+ Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481 Score = 50.4 bits (119), Expect = 2e-06 Identities = 56/211 (26%), Positives = 91/211 (43%), Gaps = 27/211 (12%) Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167 G + A + K LL D ++QE + R R EEE R K + QE+ + Sbjct: 94 GLDEEKRARCDGKESLLQD-RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL---- 148 Query: 168 HRQLHQEEDEEEEKEER--KRGPMETFEDLWQRHLENGGDLQKRVAEK----ASDKETAQ 221 E +E+ EK+ER +R E+LW++ E ++R E+ ET + Sbjct: 149 -----AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE 203 Query: 222 FQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKE 281 F EE+ R R L + +G E+++ Q E E K E R+E+E Sbjct: 204 FPDEEQLRR-----RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258 Query: 282 VEQLE------HLRDELKKVTETLGEQLRRE 306 Q E L++E +++ + ++LRRE Sbjct: 259 KLQEEEPQRQRELQEEEEQLRKLERQELRRE 289 Score = 50.4 bits (119), Expect = 2e-06 Identities = 48/196 (24%), Positives = 91/196 (46%), Gaps = 22/196 (11%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE---------- 177 +++ + R ++++ +EE+ + E K QE+ + + +L QEE++ Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012 Query: 178 --EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGD 235 E E++ RK+ ++ E+ R LQ+R + +E + Q EE+ ++LG + Sbjct: 1013 RQEWERQYRKKDELQQEEEQLLREEREKRRLQER---ERQYREEEELQQEEE--QLLGEE 1067 Query: 236 RSLWQGAERGGGERREDLPHHHHH---HHQPEAEPRQEKE-EASEREEKEVEQLEHLRDE 291 R + E R+E+ +PE RQE+E + E EE + E+ + LR+E Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127 Query: 292 L-KKVTETLGEQLRRE 306 K+ + L Q R E Sbjct: 1128 REKRRRQELERQYREE 1143 Score = 48.9 bits (115), Expect = 6e-06 Identities = 45/184 (24%), Positives = 82/184 (44%), Gaps = 15/184 (8%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKS--------EVQEQAIRMQGHRQLHQEEDEEEE 180 + E + R + + +EEE+E R + E +EQ R + +QL +EED +E Sbjct: 799 RAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE 858 Query: 181 KEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQ 240 +ER+R + + W+ LE + +KR K Q Q K ++L + Q Sbjct: 859 DQERRRSQEQRRDQKWRWQLE---EERKRRRHTLYAKPALQEQL-RKEQQLLQEEEEELQ 914 Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE--LKKVTET 298 ER RR++ + Q + E Q E E+ ++ + ++ +D+ +K + Sbjct: 915 REER-EKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973 Query: 299 LGEQ 302 LGE+ Sbjct: 974 LGEE 977 Score = 48.5 bits (114), Expect = 7e-06 Identities = 54/206 (26%), Positives = 88/206 (42%), Gaps = 32/206 (15%) Query: 118 EEKGLLLGDFKKQEAGKM----RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQ 173 EE+ LL + +K+ ++ R +EV+ EEE+ + E K QE + + +L Q Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178 Query: 174 EED----EEEEK--EERKRGPMETFEDLWQRHLENGGDLQKRVAEK-------------- 213 EE+ EE+EK +ER+R E E Q+ + D +R K Sbjct: 1179 EEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238 Query: 214 ---ASDKETAQF-QAEEKGVRVLGGDRS----LWQGAERGGGERREDLPHHHHHHHQPEA 265 +E QF Q E+ +R + L + ER + R H + E Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298 Query: 266 EPRQEKEEASEREEKEVEQLEHLRDE 291 R+E++EA R+ K E+ + LR+E Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLREE 1324 Score = 48.1 bits (113), Expect = 1e-05 Identities = 34/164 (20%), Positives = 84/164 (51%), Gaps = 8/164 (4%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 +++ ++R ++ + EEE++ + E +EQ +R Q + +EE+++ ++ER+R Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQ-----EGEEQQLRRQERDRKFREEEQQLRRQERERK 1708 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 ++ + L ++ LE ++++ + + E Q + +E+ ++L ++ + E+ Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQ---ETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE 291 + D + E E +Q + + S+R+ +E EQL R+E Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809 Score = 47.8 bits (112), Expect = 1e-05 Identities = 51/199 (25%), Positives = 98/199 (49%), Gaps = 20/199 (10%) Query: 119 EKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEE 178 E+ L L + +++E + R Q++R E+EE +R + E +E R+Q ++L E+ Sbjct: 486 ERWLKLEEEERREQQERRE-QQLRREQEERREQRLKRQEEEE---RLQ--QRLRSEQQLR 539 Query: 179 EEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS- 237 E+EER+ ++ E ++ LE Q+ E+ ++ + EE+ + L ++ Sbjct: 540 REQEERREQLLKREE---EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596 Query: 238 -LWQGAERGGGER--REDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELK- 293 L Q +R ER +E+ +PE E RQ+ ++ E+EE+ +QL + E + Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656 Query: 294 ------KVTETLGEQLRRE 306 + E L ++L+RE Sbjct: 657 QRLKREEEEERLEQRLKRE 675 Score = 47.8 bits (112), Expect = 1e-05 Identities = 56/193 (29%), Positives = 92/193 (47%), Gaps = 16/193 (8%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED----EEEEK-- 181 +++ K R +E++ EEE+ + E K QE + + +L QEE+ EE EK Sbjct: 983 RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRR 1042 Query: 182 -EERKRGPMETFEDLWQRHLENGGD---LQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237 +ER+R E E+L Q + G+ ++R + ++ + Q EE+ + ++ Sbjct: 1043 LQERERQYREE-EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101 Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKE-EASEREEKEVEQLEH--LRDE-LK 293 Q ER E E+L + E E R+ +E E REE+EV+Q E LR+E K Sbjct: 1102 RRQERERQCREE-EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160 Query: 294 KVTETLGEQLRRE 306 + + L Q R E Sbjct: 1161 RRRQELERQYREE 1173 Score = 47.8 bits (112), Expect = 1e-05 Identities = 48/189 (25%), Positives = 81/189 (42%), Gaps = 17/189 (8%) Query: 134 KMRSSQEVRDEEEEEVA---ERTHKSEVQEQAIR--------MQGHRQLHQEEDEEEEKE 182 K R +++R E EE+ ER K ++EQ +R M+ +QL ++E +++ ++ Sbjct: 1556 KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQ 1615 Query: 183 ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGV-----RVLGGDRS 237 ER R E E L Q E Q+R + ++ + Q E+ + R + Sbjct: 1616 ERDRKFRED-EQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQ 1674 Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 L Q E R+E Q + R+ K E++ + E R+E + E Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQE 1734 Query: 298 TLGEQLRRE 306 T EQLRR+ Sbjct: 1735 TEQEQLRRQ 1743 Score = 46.2 bits (108), Expect = 4e-05 Identities = 47/187 (25%), Positives = 81/187 (43%), Gaps = 19/187 (10%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE--EEEKEERK 185 +++ + R +E++ EEE+ + E K QE + + ++ QEE++ EE E+R+ Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162 Query: 186 RGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245 R +E R +LQ+ + +++ + Q E+ R + Q +R Sbjct: 1163 RQELE-------RQYREEEELQQEEEQLLREEQEKRRQERERQYR----EEEELQRQKRK 1211 Query: 246 GGERREDLPHHHHHHHQPEAE--PRQEKEEASEREEKEVEQLE--HLRDELKK--VTETL 299 R ED +PE E R K RE ++ QLE LRD + + L Sbjct: 1212 QRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLL 1271 Query: 300 GEQLRRE 306 GEQ R+ Sbjct: 1272 GEQQERD 1278 Score = 45.8 bits (107), Expect = 5e-05 Identities = 47/186 (25%), Positives = 88/186 (47%), Gaps = 12/186 (6%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVA--ERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERK 185 +++E ++ Q++R +E E+ +R K +EQ + Q + +EE+++ ++ER+ Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445 Query: 186 RGPMETFEDLWQ-RH---LENGGDLQKRVAEKASDKE-TAQFQAEEKGVRVLGGDRSLWQ 240 R +E + L Q RH E LQ+R ++ +E +F EE+ +R DR + Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505 Query: 241 GAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLG 300 R R+ L H Q ++E+ R+E+ ++ + D +K E Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ---DRDRKFREE-- 1560 Query: 301 EQLRRE 306 EQLR+E Sbjct: 1561 EQLRQE 1566 Score = 45.8 bits (107), Expect = 5e-05 Identities = 39/184 (21%), Positives = 87/184 (47%), Gaps = 16/184 (8%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE----EEEKEE 183 ++Q+ + ++ +EE++ ER K +EQ ++ + +QLH++E + EEE++ Sbjct: 1435 EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQL 1494 Query: 184 RKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAE 243 R++ F + +L+ + E+ +E Q +++ + L ++ L + + Sbjct: 1495 RRQERDRKFRE---------QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRR--Q 1543 Query: 244 RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEK-EVEQLEHLRDELKKVTETLGEQ 302 G +RR+D Q E +++ ER+ K +E+ + R E ++ +Q Sbjct: 1544 ERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603 Query: 303 LRRE 306 LRR+ Sbjct: 1604 LRRQ 1607 Score = 45.4 bits (106), Expect = 6e-05 Identities = 40/171 (23%), Positives = 75/171 (43%), Gaps = 6/171 (3%) Query: 136 RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDL 195 R Q++R E+EEE E+ + E +E+ Q R+ +++ +E++ R + + Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405 Query: 196 WQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPH 255 R + Q+ E+ +E + + E+K + R + ER +RE+ Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465 Query: 256 HHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 H + + R ++EE ER K E+ E ++ E +QLRRE Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEE------ERREQQERREQQLRRE 510 Score = 45.1 bits (105), Expect = 8e-05 Identities = 41/187 (21%), Positives = 85/187 (45%), Gaps = 9/187 (4%) Query: 127 FKKQEAGKMRSSQEVRDEEEE-EVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERK 185 F++QE ++ +EE++ +R K +EQ +R Q Q +++ + + +EE + Sbjct: 1503 FREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQ 1562 Query: 186 RGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245 + L ++ + L+++ + ++ +F +E+ +R G + L Q +R Sbjct: 1563 LRQEREEQQLSRQERDRKFRLEEQKVRR--QEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620 Query: 246 GGERREDLPHHHHHH-HQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETL----- 299 E + L H+ E + + +EE R ++ +QL H RD + E L Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680 Query: 300 GEQLRRE 306 +QLRR+ Sbjct: 1681 EQQLRRQ 1687 Score = 44.3 bits (103), Expect = 1e-04 Identities = 48/217 (22%), Positives = 92/217 (42%), Gaps = 40/217 (18%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAER----------THKSEVQEQAIRMQGHRQL-----H 172 K+QE + + E + E++E + +R + E QE+ R QL H Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199 Query: 173 QEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKE-------------- 218 + E+ +E++ R+R +E + + + Q RV ++ +KE Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259 Query: 219 --------TAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQE 270 + Q EE+ +R L +R + + ++++ L + E E R++ Sbjct: 260 LQEEEPQRQRELQEEEEQLRKL--ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317 Query: 271 KEEASEREEKEVEQLEHLRDELKKVTETLGE-QLRRE 306 +EE E++E+ +Q E +L++ E E QLRRE Sbjct: 318 QEERREQQERREQQEERREQQLRREQEERREQQLRRE 354 Score = 44.3 bits (103), Expect = 1e-04 Identities = 49/199 (24%), Positives = 84/199 (42%), Gaps = 26/199 (13%) Query: 134 KMRSSQEVRDEEEEEVA-ERTHKSEVQEQAIRMQGHRQLHQEED-------EEEEKEERK 185 ++R Q++ EEEEE+ E K QEQ + + QL QEE+ E+ ++ER+ Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957 Query: 186 RGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDR--------- 236 R + + + G + +KR ++ K + + +++ ++L +R Sbjct: 958 RQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017 Query: 237 -------SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLR 289 L Q E+ E RE E E Q++EE EE+E + + L Sbjct: 1018 RQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELE 1077 Query: 290 DELKKVTETL--GEQLRRE 306 + +K E EQL RE Sbjct: 1078 RQYRKEEELQQEEEQLLRE 1096 Score = 44.3 bits (103), Expect = 1e-04 Identities = 53/210 (25%), Positives = 93/210 (44%), Gaps = 27/210 (12%) Query: 118 EEKGLLLGDFKKQEAGKM----RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQ 173 EE+ LL + +K+ + R E++ EEE+ + E K +QE+ RQ + Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER------ERQYRE 1052 Query: 174 EED-EE-------EEKEERKRGPME----TFEDLWQRH---LENGGDLQKRVAEKASDKE 218 EE+ ++ EE+E R+R +E E+L Q L + ++R + +E Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112 Query: 219 TAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASERE 278 + Q EE+ + ++ Q ER E E + + R+++ E RE Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172 Query: 279 EKEVEQLEH--LRDELKKVTETLGEQLRRE 306 E+E++Q E LR+E +K + Q R E Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREE 1202 Score = 43.9 bits (102), Expect = 2e-04 Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 14/173 (8%) Query: 136 RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERK--RGPMETFE 193 R Q+++ ++EEE ER K E +E+ +Q +E+ E+EER+ R + E Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERR-----EQQERREQQLRREQEERREQRLKRQEEE 525 Query: 194 DLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDL 253 + Q+ L + L++ E+ +E + EEK + ++ L +R ERR+ L Sbjct: 526 ERLQQRLRSEQQLRREQEER---REQLLKREEEKRLEQERREQRL----KREQEERRDQL 578 Query: 254 PHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 Q + QE+ + +EVE+LE +++ E+ RR+ Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631 Score = 43.1 bits (100), Expect = 3e-04 Identities = 45/177 (25%), Positives = 76/177 (42%), Gaps = 27/177 (15%) Query: 134 KMRSSQEVRDEEE--EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMET 191 ++R Q++R E++ E R + +EQ +R + + QEE+ E+K E++R Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR---- 443 Query: 192 FEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERRE 251 E +R E D KR ++ET + + E + + L + E ER Sbjct: 444 -EQRLKREQEERRDWLKR------EEETERHEQERR-------KQQLKRDQEEERRERWL 489 Query: 252 DLPHHHHHHHQPEAEPRQEKEEASEREE--KEVEQLEHLRDELKKVTETLGEQLRRE 306 L Q E + +E+ RE+ K E+ E L+ L+ +QLRRE Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS-----EQQLRRE 541 Score = 43.1 bits (100), Expect = 3e-04 Identities = 40/182 (21%), Positives = 82/182 (45%), Gaps = 11/182 (6%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEE--EEEVAERTHKSEVQEQAIRMQG-----HRQ 170 E + LL +++ +++ QE R E+ + E ER + E +EQ ++ + +Q Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ 632 Query: 171 LHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVR 230 L + E++EE ++++ R + + + E L++R+ + ++ Q AEE+ + Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692 Query: 231 VLGGDRS---LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEH 287 +S WQ + R+ + + + RQE+EE R E E++ E Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRR-RQEQEEKRRRRESELQWQEE 751 Query: 288 LR 289 R Sbjct: 752 ER 753 Score = 42.0 bits (97), Expect = 7e-04 Identities = 41/182 (22%), Positives = 77/182 (42%), Gaps = 19/182 (10%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 +++ K+ +++R E EE+ R QE+ + + QL QE +E++ + + Sbjct: 1742 RQERYRKILEEEQLRPEREEQQLRR------QERDRKFREEEQLRQEREEQQLRSQESDR 1795 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 E L Q E Q+R + ++E Q + +E+ +R ER Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR-----------QERDRQ 1844 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVT--ETLGEQLRR 305 R E+ + E E QE+E+ +E + + EH+R + K+ +GE + Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904 Query: 306 EG 307 EG Sbjct: 1905 EG 1906 Score = 41.2 bits (95), Expect = 0.001 Identities = 48/193 (24%), Positives = 85/193 (44%), Gaps = 29/193 (15%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE-----KE 182 ++Q + + Q + +EE+ + ER + + +E ++ R+ QE+ +++ +E Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE 880 Query: 183 ERKR---------GPMETFEDLWQRHLENGGDLQKRVAEK-------ASDKETAQFQAEE 226 ERKR E Q E +LQ+ EK +E Q Q EE Sbjct: 881 ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940 Query: 227 KGVRVLGGDRSLWQGAERGGGERREDLPHHHHHH---HQPEAEPRQEKEEASEREEKEVE 283 + ++L +R + ER R++ +PE RQE+E+ REE+E++ Sbjct: 941 E--QLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK-KYREEEELQ 997 Query: 284 QLEH--LRDELKK 294 Q E LR+E +K Sbjct: 998 QEEEQLLREEREK 1010 Score = 40.8 bits (94), Expect = 0.002 Identities = 37/174 (21%), Positives = 81/174 (46%), Gaps = 12/174 (6%) Query: 118 EEKGLLLGDFK----KQEAGKM-RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLH 172 +E+ LLG+ + +QE + R +E++ EEE+ + E K QE+ + + +L Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQ 1117 Query: 173 QEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVL 232 QEE E+ +EER++ + E ++ E + ++ + E+ + + + + + Sbjct: 1118 QEE-EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR----- 1171 Query: 233 GGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286 + L Q E+ E +E ++ E E +++K + R+E + L+ Sbjct: 1172 -EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLK 1224 Score = 39.3 bits (90), Expect = 0.004 Identities = 54/220 (24%), Positives = 96/220 (43%), Gaps = 34/220 (15%) Query: 119 EKGLLLGDFKKQEAGKMRSSQEVRDEEEE-EVAERTHKSEVQEQAIRMQ-------GHRQ 170 E+ LL + ++Q+ + ++ R+EE++ ER K +EQ +R Q Q Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ 1730 Query: 171 LHQEEDEEE-EKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGV 229 L QE ++E+ ++ER R +E E L E Q+R K ++E + + EE+ + Sbjct: 1731 LRQETEQEQLRRQERYRKILEE-EQLRPEREEQQLRRQER-DRKFREEEQLRQEREEQQL 1788 Query: 230 RVLGGDRSLWQGAE-RGGGERREDLPHHHHHHHQPEAEP----------RQEK------- 271 R DR + + R E ++ P ++ E E RQE+ Sbjct: 1789 RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE 1848 Query: 272 -----EEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 +E S REE+E+ Q E + ++ + E +RR+ Sbjct: 1849 EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888 Score = 38.1 bits (87), Expect = 0.010 Identities = 44/190 (23%), Positives = 83/190 (43%), Gaps = 23/190 (12%) Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQ------EQAIRMQGHRQLHQE-----EDEEEEKE 182 K R +++ R E+ ++ +R + ++Q ++ R Q R+ Q E+E+ E+E Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302 Query: 183 ERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242 E+K + ++ L L++ EK +ET + EE+ + ++ L + Sbjct: 1303 EQKEAKRRDRKSQEEKQL-----LREEREEKRRRQETDRKFREEEQLLQEREEQPL-RRQ 1356 Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQL------EHLRDELKKVT 296 ER R E+L H E E R ++E + KE +QL + LR + + Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKF 1416 Query: 297 ETLGEQLRRE 306 +QL R+ Sbjct: 1417 REEEQQLSRQ 1426 Score = 37.7 bits (86), Expect = 0.013 Identities = 42/165 (25%), Positives = 77/165 (46%), Gaps = 17/165 (10%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 EEK L + +++E R +E RD+ + ER + +EQ R++ ++L +EE E Sbjct: 554 EEKRL---EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE--QRLKREEVE 608 Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRS 237 E+EER+ ++ E +R Q +E+ ++ Q + E++ R ++ Sbjct: 609 RLEQEERREQRLKREEPEEERRQ------QLLKSEEQEERRQQQLRREQQERR----EQR 658 Query: 238 LWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEV 282 L + E E+R H Q AE +E+E+A ER + + Sbjct: 659 LKREEEEERLEQRLKREHEEERREQELAE--EEQEQARERIKSRI 701 Score = 37.7 bits (86), Expect = 0.013 Identities = 42/175 (24%), Positives = 79/175 (45%), Gaps = 23/175 (13%) Query: 119 EKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEE 178 E+ LL + ++Q + ++ R EEE E+ K +EQ +R Q + +E+++ Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFR-EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398 Query: 179 EEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSL 238 +ER++ + +D ++ E L ++ ++ +F+ EE+ VR Sbjct: 1399 LRCQEREQ---QLRQDRDRKFREEEQQLSRQERDR-------KFREEEQQVR-------- 1440 Query: 239 WQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEE----ASEREEKEVEQLEHLR 289 Q ER E + L H + E + QE+EE ER+ K +E+ + LR Sbjct: 1441 RQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR 1495 Score = 37.0 bits (84), Expect = 0.022 Identities = 40/184 (21%), Positives = 73/184 (39%), Gaps = 18/184 (9%) Query: 136 RSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEED--------EEEEKEERKRG 187 R + R +E+E R +SE+Q Q + HRQ +EE + EEK ER R Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQE-EERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782 Query: 188 PMETFEDLWQRH-----LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242 + L ++ E ++R + +KE + Q E+ + + L + Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL----QFLEEEE 838 Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302 + ER + L + + R +++ ++ ++E+ R L EQ Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898 Query: 303 LRRE 306 LR+E Sbjct: 899 LRKE 902 Score = 35.8 bits (81), Expect = 0.049 Identities = 44/182 (24%), Positives = 83/182 (45%), Gaps = 21/182 (11%) Query: 128 KKQEAGKMRSS----------QEVRDEEEEEVAER-THKSEVQEQAIRMQGHRQLHQEED 176 +K E G+ R S +++R EE ++ +R + E +EQ R + R+ + Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFL 834 Query: 177 EEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVR-VLGGD 235 EEEE+ +R+ + E+ + L+ + ++ ++ K Q + E K R L Sbjct: 835 EEEEQLQRRERAQQLQEE--EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892 Query: 236 RSLWQGAERGG---GERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDEL 292 +L + + E E+L + + + RQ +EE E+ ++E EQL LR+E Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE--EQLQQEEEQL--LREER 948 Query: 293 KK 294 +K Sbjct: 949 EK 950 Score = 28.5 bits (62), Expect = 7.8 Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Query: 127 FKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKR 186 F QE + R QE+ EEE++ + + +E R Q Q H++ E + +E + Sbjct: 1851 FATQEKSR-REEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGH 1909 Query: 187 G 187 G Sbjct: 1910 G 1910 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 54.7 bits (130), Expect = 1e-07 Identities = 47/178 (26%), Positives = 88/178 (49%), Gaps = 21/178 (11%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 ++QE R +++R E+EE++ E+ K QE+ IR Q + QEE+ ++E+ + Sbjct: 342 REQEDKMWRQEEKIR-EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 + E +W++ + + EK ++E ++ EEK +R L + Q E Sbjct: 401 EEKRQEKMWRQEKK-----MREQDEKIREQEEEMWRQEEK-IREL---EEMMQDQEEKLR 451 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEH---LRDELKKVTETLGEQ 302 E E + Q E E QE+EE +R+E+++++ E +++L K E + EQ Sbjct: 452 EVEEKM--------QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501 Score = 52.4 bits (124), Expect = 5e-07 Identities = 50/188 (26%), Positives = 86/188 (45%), Gaps = 16/188 (8%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE-- 175 EEK L + + + K+R +E EEEE++ E+ K + QE+ I+ Q + QE+ Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492 Query: 176 DEEEEKEERKRGPMETFEDLWQRH--LENGGDLQKRVAEKASDKETAQFQAEEK----GV 229 +EE+ E++ E +W++ ++ + +R EK ++E +Q EEK V Sbjct: 493 KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552 Query: 230 RVLGGDR---SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286 R+ + L Q AE GG RE P P + E S+ + +Q + Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRES-----GSQRLPTLTPILQVELKSQEAQSLQQQQD 607 Query: 287 HLRDELKK 294 H R L++ Sbjct: 608 HYRGHLQQ 615 Score = 52.0 bits (123), Expect = 7e-07 Identities = 43/207 (20%), Positives = 98/207 (47%), Gaps = 15/207 (7%) Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161 L KEL A EE L +Q+ KM +E E+EE++ E+ K QE+ Sbjct: 267 LGKELQSVSAKLQAQVEENELW-NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE 325 Query: 162 AIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQ 221 + Q ++H++E++ E+E++ +W++ E + ++++ E+ + Sbjct: 326 KMWRQ-EEKMHEQEEKIREQEDK----------MWRQE-EKIREQEEKIREQEEKMWRQE 373 Query: 222 FQAEEKGVRVLGGDRSLWQGAE--RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREE 279 + E+ ++ + +W+ E R E+R++ + + E +E+EE R+E Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433 Query: 280 KEVEQLEHLRDELKKVTETLGEQLRRE 306 +++ +LE + + ++ + E+++ E Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEE 460 Score = 48.9 bits (115), Expect = 6e-06 Identities = 41/185 (22%), Positives = 87/185 (47%), Gaps = 8/185 (4%) Query: 128 KKQEAGKMRSSQEVRDEEE---EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184 ++QE R +++R++EE E++ + K Q++ IR Q ++ ++E++ E EE Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ-EEEMWRQEEKIRELEEM 442 Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEE--KGVRVLGGDRSLWQGA 242 + E ++ ++ E +Q++ + +E Q Q E+ + ++L + +W+ Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502 Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302 E+ R+E+ Q + E Q +EE +E + Q E E + + L E+ Sbjct: 503 EKMW--RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560 Query: 303 LRREG 307 L + G Sbjct: 561 LGKLG 565 Score = 47.0 bits (110), Expect = 2e-05 Identities = 40/179 (22%), Positives = 88/179 (49%), Gaps = 15/179 (8%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 ++QE R +++R E++E++ E+ + QE+ IR Q ++ + +E++ E+ Sbjct: 363 REQEEKMWRQEEKIR-EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK 421 Query: 188 PMETFEDLWQRH---------LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSL 238 E E++W++ +++ + + V EK ++E + EEK R + + Sbjct: 422 IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ---EEKI 478 Query: 239 WQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 + E+ R+E L + E + +++E+ E+EEK EQ E ++ + +K+ E Sbjct: 479 QEQEEKTW--RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535 Score = 40.8 bits (94), Expect = 0.002 Identities = 54/239 (22%), Positives = 100/239 (41%), Gaps = 24/239 (10%) Query: 88 LTVGQV--QRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEE 145 L +G+V Q+ P +LL + L + EK D E + + E E+ Sbjct: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEK 219 Query: 146 EEEVAER-----THKSEVQ----------EQAIRMQGHRQLHQEED---EEEEKEERKRG 187 E+ E+ + KSE+Q E+A + +QL E D +E + K Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 +LW + + R EK ++E + E +++ + +W+ E+ Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE---LKIREQEEKMWRQEEKMH- 335 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 E+ E + + E + R+++E+ E+EEK Q E +R++ +K+ E E R+E Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE 394 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 54.7 bits (130), Expect = 1e-07 Identities = 47/178 (26%), Positives = 88/178 (49%), Gaps = 21/178 (11%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 ++QE R +++R E+EE++ E+ K QE+ IR Q + QEE+ ++E+ + Sbjct: 342 REQEDKMWRQEEKIR-EQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQ 400 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 + E +W++ + + EK ++E ++ EEK +R L + Q E Sbjct: 401 EEKRQEKMWRQEKK-----MREQDEKIREQEEEMWRQEEK-IREL---EEMMQDQEEKLR 451 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEH---LRDELKKVTETLGEQ 302 E E + Q E E QE+EE +R+E+++++ E +++L K E + EQ Sbjct: 452 EVEEKM--------QEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQ 501 Score = 52.4 bits (124), Expect = 5e-07 Identities = 50/188 (26%), Positives = 86/188 (45%), Gaps = 16/188 (8%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEE-- 175 EEK L + + + K+R +E EEEE++ E+ K + QE+ I+ Q + QE+ Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL 492 Query: 176 DEEEEKEERKRGPMETFEDLWQRH--LENGGDLQKRVAEKASDKETAQFQAEEK----GV 229 +EE+ E++ E +W++ ++ + +R EK ++E +Q EEK V Sbjct: 493 KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552 Query: 230 RVLGGDR---SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286 R+ + L Q AE GG RE P P + E S+ + +Q + Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRES-----GSQRLPTLTPILQVELKSQEAQSLQQQQD 607 Query: 287 HLRDELKK 294 H R L++ Sbjct: 608 HYRGHLQQ 615 Score = 52.0 bits (123), Expect = 7e-07 Identities = 43/207 (20%), Positives = 98/207 (47%), Gaps = 15/207 (7%) Query: 102 LHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQ 161 L KEL A EE L +Q+ KM +E E+EE++ E+ K QE+ Sbjct: 267 LGKELQSVSAKLQAQVEENELW-NLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE 325 Query: 162 AIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQ 221 + Q ++H++E++ E+E++ +W++ E + ++++ E+ + Sbjct: 326 KMWRQ-EEKMHEQEEKIREQEDK----------MWRQE-EKIREQEEKIREQEEKMWRQE 373 Query: 222 FQAEEKGVRVLGGDRSLWQGAE--RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREE 279 + E+ ++ + +W+ E R E+R++ + + E +E+EE R+E Sbjct: 374 EKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE 433 Query: 280 KEVEQLEHLRDELKKVTETLGEQLRRE 306 +++ +LE + + ++ + E+++ E Sbjct: 434 EKIRELEEMMQDQEEKLREVEEKMQEE 460 Score = 48.9 bits (115), Expect = 6e-06 Identities = 41/185 (22%), Positives = 87/185 (47%), Gaps = 8/185 (4%) Query: 128 KKQEAGKMRSSQEVRDEEE---EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184 ++QE R +++R++EE E++ + K Q++ IR Q ++ ++E++ E EE Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ-EEEMWRQEEKIRELEEM 442 Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEE--KGVRVLGGDRSLWQGA 242 + E ++ ++ E +Q++ + +E Q Q E+ + ++L + +W+ Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502 Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302 E+ R+E+ Q + E Q +EE +E + Q E E + + L E+ Sbjct: 503 EKMW--RQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560 Query: 303 LRREG 307 L + G Sbjct: 561 LGKLG 565 Score = 47.0 bits (110), Expect = 2e-05 Identities = 40/179 (22%), Positives = 88/179 (49%), Gaps = 15/179 (8%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 ++QE R +++R E++E++ E+ + QE+ IR Q ++ + +E++ E+ Sbjct: 363 REQEEKMWRQEEKIR-EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK 421 Query: 188 PMETFEDLWQRH---------LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSL 238 E E++W++ +++ + + V EK ++E + EEK R + + Sbjct: 422 IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ---EEKI 478 Query: 239 WQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 + E+ R+E L + E + +++E+ E+EEK EQ E ++ + +K+ E Sbjct: 479 QEQEEKTW--RQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535 Score = 40.4 bits (93), Expect = 0.002 Identities = 54/239 (22%), Positives = 100/239 (41%), Gaps = 24/239 (10%) Query: 88 LTVGQV--QRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEE 145 L +G+V Q+ P +LL + L + EK D E + + E E+ Sbjct: 160 LRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEK 219 Query: 146 EEEVAER-----THKSEVQ----------EQAIRMQGHRQLHQEED---EEEEKEERKRG 187 E+ E+ + KSE+Q E+A + +QL E D +E + K Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 +LW + + R EK ++E + E +++ + +W+ E+ Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQE---LKIREQEEKMWRQEEKMH- 335 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 E+ E + + E + R+++E+ E+EEK Q E +R++ +K+ E E R+E Sbjct: 336 EQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE 394 >gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo sapiens] Length = 1152 Score = 52.4 bits (124), Expect = 5e-07 Identities = 50/184 (27%), Positives = 74/184 (40%), Gaps = 6/184 (3%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTH----KSEVQEQAIRMQGHRQLHQEEDEEEEKEE 183 +K E K R E E E+E+AE+ E QEQ R QGH++ +E EE +EE Sbjct: 675 EKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEE 734 Query: 184 RKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAE 243 G E + + E G + E ++E + E K G + + + Sbjct: 735 HGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEE--GERKKEERAGKEEKGEEEGD 792 Query: 244 RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQL 303 +G GE E E E + +E EREE+E E + + E GE+ Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE 852 Query: 304 RREG 307 EG Sbjct: 853 EGEG 856 Score = 50.4 bits (119), Expect = 2e-06 Identities = 53/204 (25%), Positives = 86/204 (42%), Gaps = 6/204 (2%) Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167 G E G EE+G ++ E G+ +E + E EE E + E E +G Sbjct: 849 GEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG 908 Query: 168 HRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENG-GDLQKRVAEKASDKETAQFQAEE 226 + +EE E + +EE + G E E+ + E+G G+ ++ E ++E + + EE Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968 Query: 227 KGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASERE---EKEVE 283 +G G+ +G E G E+ + E E E E E E E EVE Sbjct: 969 EGEGE--GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVE 1026 Query: 284 QLEHLRDELKKVTETLGEQLRREG 307 E + ++ E GE+ +EG Sbjct: 1027 GEEGEGEGEEEEGEEEGEEREKEG 1050 Score = 49.3 bits (116), Expect = 4e-06 Identities = 55/216 (25%), Positives = 84/216 (38%), Gaps = 25/216 (11%) Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167 G + G E G + ++E K R +E +E E+ ++ E++E G Sbjct: 677 GEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG 736 Query: 168 HRQLHQ---EEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQA 224 + + EE+EE+E E ++ G E E +R E G ++ A K E Q Sbjct: 737 EGEEEEGDREEEEEKEGEGKEEGEGEEVEG--EREKEEGERKKEERAGKEEKGEEEGDQG 794 Query: 225 E-------------EKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEK 271 E E+G V GG+ E G GER E+ + E E + + Sbjct: 795 EGEEEETEGRGEEKEEGGEVEGGE------VEEGKGEREEEEEEGEGEEEEGEGEEEEGE 848 Query: 272 EEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307 E E E K E+ E E ++ E GE EG Sbjct: 849 GEEEEGEGKGEEEGEEGEGE-EEGEEGEGEGEEEEG 883 Score = 48.1 bits (113), Expect = 1e-05 Identities = 46/180 (25%), Positives = 74/180 (41%), Gaps = 2/180 (1%) Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167 G E G EE+G G+ + +E +E E EEE E + E + + +G Sbjct: 842 GEEEEG-EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 900 Query: 168 HRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEK 227 + +E + E E+EE + E E+ E G+ + E ++E +++ EE+ Sbjct: 901 EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960 Query: 228 GVRVLGGDRSLWQGAE-RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLE 286 G + +G E G GE E + E E E EE E E +E E+ E Sbjct: 961 EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020 Score = 47.4 bits (111), Expect = 2e-05 Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 8/193 (4%) Query: 118 EEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDE 177 EE G + G ++ G+ +E + EEEE + E +E+ +G + + E E Sbjct: 809 EEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868 Query: 178 EEEKEERKRGPMETFEDLWQRHLENGGDLQ------KRVAEKASDKETAQFQAEEKGVRV 231 EE +E G E E + E G+ + + E ++E + + EE+G Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928 Query: 232 LG-GDRSLWQG-AERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLR 289 G G+ +G E G GE E+ + E E +E E E E E E+ E Sbjct: 929 EGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEG 988 Query: 290 DELKKVTETLGEQ 302 + ++ E GE+ Sbjct: 989 EGEEEEGEEEGEE 1001 Score = 46.2 bits (108), Expect = 4e-05 Identities = 49/199 (24%), Positives = 78/199 (39%), Gaps = 6/199 (3%) Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAE---RTHKSEVQEQAIR 164 G E G EE+G G+ ++ E +E E EEE E + E +E+ Sbjct: 895 GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE 954 Query: 165 MQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQA 224 +G + + E EEE + E + G E E+ + E ++ E ++E Sbjct: 955 WEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGE 1014 Query: 225 EEKGVRVLG---GDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKE 281 EE+ V G G+ +G E G E E+ +E+EE +E E Sbjct: 1015 EEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGE 1074 Query: 282 VEQLEHLRDELKKVTETLG 300 E +E KKV++ G Sbjct: 1075 EENERQDGEEYKKVSKIKG 1093 Score = 38.9 bits (89), Expect = 0.006 Identities = 41/184 (22%), Positives = 80/184 (43%), Gaps = 15/184 (8%) Query: 128 KKQEAGKMRSSQEVRDE---EEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184 K + G+ E R + EE + E +E+ + +G ++ + + E+E E+ Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEK 699 Query: 185 KRGPMETFEDLWQRHLENGGDLQK-RVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAE 243 + E+ Q+ E G ++ + E+ ++E + + EE GDR + E Sbjct: 700 EEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEE-------GDR---EEEE 749 Query: 244 RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQL 303 GE +E+ + + E ++KEE + +EEK E+ + E ++ TE GE+ Sbjct: 750 EKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE-EEETEGRGEEK 808 Query: 304 RREG 307 G Sbjct: 809 EEGG 812 Score = 36.6 bits (83), Expect = 0.029 Identities = 47/175 (26%), Positives = 74/175 (42%), Gaps = 27/175 (15%) Query: 137 SSQEVRDEEEEEVAERTHKSEVQEQA-------IRMQGHRQLHQE--EDEEEEKEERKRG 187 S +EV EE+E AE + + ++EQ +++ G R+ E D+ +K E G Sbjct: 580 SDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEG 639 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLG---------GDRSL 238 ++ + + E GD E +S E Q + EKG + G G++ L Sbjct: 640 KAKSVGEA-EDGPEGRGD--GTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKEL 696 Query: 239 WQGAE--RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDE 291 + E + GE +E H + E QE EE E E E E+ E R+E Sbjct: 697 AEKEEWKKRDGEEQEQKEREQGH----QKERNQEMEEGGEEEHGEGEEEEGDREE 747 Score = 30.8 bits (68), Expect = 1.6 Identities = 55/234 (23%), Positives = 94/234 (40%), Gaps = 46/234 (19%) Query: 116 STEEKGLLLGDFKKQEA----GKMRSSQEVRD----EEEEEVAE----RTHKSEVQEQAI 163 ++ EK L L +KQ+ G++ + + +E EE++E + K V + Sbjct: 509 NSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIF 568 Query: 164 RMQGHRQLHQEEDEEEEKEERKRGPMET-----FEDLWQRHLEN----GGDLQKRVAEKA 214 Q + DEE E E K G ++ E + + EN GG +K E Sbjct: 569 MTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGG--RKEKTEIL 626 Query: 215 SDKETAQFQAEEKGVRVLG---------GDRSL---------WQGAERGGGER---REDL 253 SD T + + E + +G GD + WQ ER GE+ R ++ Sbjct: 627 SDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEM 686 Query: 254 PHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307 + + +K + E+E+KE EQ H ++ +++ E GE+ EG Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQKEREQ-GHQKERNQEMEEG-GEEEHGEG 738 >gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo sapiens] Length = 916 Score = 51.2 bits (121), Expect = 1e-06 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 11/159 (6%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGP 188 K EA K++ + +E EE KSE++E + + +E+++E EE++ P Sbjct: 440 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 499 Query: 189 METFEDLWQRHLE---NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245 E++ + ++++ EK ++ + + E++G + AE G Sbjct: 500 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKS--------DQAEEG 551 Query: 246 GGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQ 284 G E+ + E E E EEA +EEK+VE+ Sbjct: 552 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 590 Score = 40.8 bits (94), Expect = 0.002 Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 21/192 (10%) Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167 G P + EEKG K + S + EE+ KS V+E + + Sbjct: 639 GKSPVPKSPVEEKGK--SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV 696 Query: 168 HRQLHQEEDEEEEKEERKRGPMETFE----DLWQRHLENGGDLQKRVA------------ 211 + +EE+E+E KE K +E E D+ ++ ++ VA Sbjct: 697 GKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVH 756 Query: 212 -EKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG-GERREDLPHHHHHHHQPEAEPRQ 269 EK + +E Q E++ + G S +G+++G G R+ED+ + + E E ++ Sbjct: 757 LEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE-QE 815 Query: 270 EKEEASEREEKE 281 KE+ S REE++ Sbjct: 816 TKEKGSGREEEK 827 Score = 36.2 bits (82), Expect = 0.037 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 13/115 (11%) Query: 115 ASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQE 174 A TEE + + + KK+ A +E + EEEEVA + + ++ + + +E Sbjct: 475 AITEELAVSMKEEKKEAA---EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEE 531 Query: 175 EDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEK-ASDKETAQFQAEEKG 228 EEEE+E+ E E GG ++ +EK ++E + +AE +G Sbjct: 532 GQEEEEEED---------EGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG 577 Score = 30.0 bits (66), Expect = 2.7 Identities = 41/215 (19%), Positives = 79/215 (36%), Gaps = 54/215 (25%) Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVR--DEEEEEVA--------------- 150 G+E G + EE G+ + + G+ ++E + +E+ EEVA Sbjct: 552 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 611 Query: 151 -----------ERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRH 199 E KS V + + +G + + EE+ K + P+E Sbjct: 612 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEE-------- 663 Query: 200 LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHH 259 + + K E+ + + EE + AE G GE++E+ Sbjct: 664 -KGKSPVSKSPVEEKAKSPVPKSPVEEAKSK-----------AEVGKGEQKEE------E 705 Query: 260 HHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294 + + P++EK E E + K+V + + +K+ Sbjct: 706 EKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 740 Score = 28.9 bits (63), Expect = 6.0 Identities = 31/137 (22%), Positives = 55/137 (40%), Gaps = 15/137 (10%) Query: 73 KEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEA 132 K E+ L +TE L V + A +E E A+ + K+E Sbjct: 466 KSEMEEALT-AITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE 524 Query: 133 GKMRSSQEVRDEEEEEVAERTHKSEV----------QEQAIRMQGHRQLHQEEDE----E 178 G+ + +EEEE+ ++ ++E +E+ + +G + E +E E Sbjct: 525 GEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKE 584 Query: 179 EEKEERKRGPMETFEDL 195 E+K E K + T E+L Sbjct: 585 EKKVEEKSEEVATKEEL 601 >gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo sapiens] Length = 540 Score = 51.2 bits (121), Expect = 1e-06 Identities = 37/159 (23%), Positives = 70/159 (44%), Gaps = 11/159 (6%) Query: 129 KQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGP 188 K EA K++ + +E EE KSE++E + + +E+++E EE++ P Sbjct: 64 KVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEP 123 Query: 189 METFEDLWQRHLE---NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERG 245 E++ + ++++ EK ++ + + E++G + AE G Sbjct: 124 EAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKS--------DQAEEG 175 Query: 246 GGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQ 284 G E+ + E E E EEA +EEK+VE+ Sbjct: 176 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 214 Score = 40.8 bits (94), Expect = 0.002 Identities = 47/192 (24%), Positives = 82/192 (42%), Gaps = 21/192 (10%) Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQG 167 G P + EEKG K + S + EE+ KS V+E + + Sbjct: 263 GKSPVPKSPVEEKGK--SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV 320 Query: 168 HRQLHQEEDEEEEKEERKRGPMETFE----DLWQRHLENGGDLQKRVA------------ 211 + +EE+E+E KE K +E E D+ ++ ++ VA Sbjct: 321 GKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVH 380 Query: 212 -EKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGG-GERREDLPHHHHHHHQPEAEPRQ 269 EK + +E Q E++ + G S +G+++G G R+ED+ + + E E ++ Sbjct: 381 LEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVE-QE 439 Query: 270 EKEEASEREEKE 281 KE+ S REE++ Sbjct: 440 TKEKGSGREEEK 451 Score = 36.2 bits (82), Expect = 0.037 Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 13/115 (11%) Query: 115 ASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQE 174 A TEE + + + KK+ A +E + EEEEVA + + ++ + + +E Sbjct: 99 AITEELAVSMKEEKKEAA---EEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEE 155 Query: 175 EDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEK-ASDKETAQFQAEEKG 228 EEEE+E+ E E GG ++ +EK ++E + +AE +G Sbjct: 156 GQEEEEEED---------EGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEG 201 Score = 30.0 bits (66), Expect = 2.7 Identities = 41/215 (19%), Positives = 79/215 (36%), Gaps = 54/215 (25%) Query: 108 GTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVR--DEEEEEVA--------------- 150 G+E G + EE G+ + + G+ ++E + +E+ EEVA Sbjct: 176 GSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPE 235 Query: 151 -----------ERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRH 199 E KS V + + +G + + EE+ K + P+E Sbjct: 236 KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEE-------- 287 Query: 200 LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHH 259 + + K E+ + + EE + AE G GE++E+ Sbjct: 288 -KGKSPVSKSPVEEKAKSPVPKSPVEEAKSK-----------AEVGKGEQKEE------E 329 Query: 260 HHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294 + + P++EK E E + K+V + + +K+ Sbjct: 330 EKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKE 364 Score = 28.9 bits (63), Expect = 6.0 Identities = 31/137 (22%), Positives = 55/137 (40%), Gaps = 15/137 (10%) Query: 73 KEELTRCLAEVVTEVLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEA 132 K E+ L +TE L V + A +E E A+ + K+E Sbjct: 90 KSEMEEALT-AITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEE 148 Query: 133 GKMRSSQEVRDEEEEEVAERTHKSEV----------QEQAIRMQGHRQLHQEEDE----E 178 G+ + +EEEE+ ++ ++E +E+ + +G + E +E E Sbjct: 149 GEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKE 208 Query: 179 EEKEERKRGPMETFEDL 195 E+K E K + T E+L Sbjct: 209 EKKVEEKSEEVATKEEL 225 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 50.4 bits (119), Expect = 2e-06 Identities = 41/167 (24%), Positives = 77/167 (46%), Gaps = 8/167 (4%) Query: 140 EVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRH 199 E+R+ E E + K E + + R + R+ + + E E++ +R+RG E + ++ Sbjct: 37 EIREREREIETRKEGKKERESE--RKKERREREKRKREREKERKRERGKKEKKGE--RKK 92 Query: 200 LENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHH 259 E ++R E +E + + +EK R R+ +G ER E R+ Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKER----GRTSKEGKERERKEERKREERKERE 148 Query: 260 HHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRRE 306 + E E +E++E +RE K+V + E R E ++ E+ R+E Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195 Score = 47.8 bits (112), Expect = 1e-05 Identities = 37/174 (21%), Positives = 81/174 (46%), Gaps = 20/174 (11%) Query: 125 GDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEER 184 G+ KK+E + + +E ++E EE +R K + + +G + +EE + EE++ER Sbjct: 88 GERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147 Query: 185 KRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAER 244 +R E ++ + E +K+V EK +++ + + +K ER Sbjct: 148 ERKKEEREKE--RERKERKKRERKQVGEKEEERKEKERKERKK--------------RER 191 Query: 245 GGGERREDLPHHHHHHHQPEAEPRQEKEEASEREE----KEVEQLEHLRDELKK 294 ER+++ + E + ++E+++ +++ +E E+ + R E KK Sbjct: 192 NRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245 Score = 41.6 bits (96), Expect = 9e-04 Identities = 34/167 (20%), Positives = 76/167 (45%), Gaps = 7/167 (4%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 KK+ + + +E E + E ++ K E +++ R + R+ +E E EEKE+RK+ Sbjct: 60 KKERREREKRKREREKERKRERGKKEKKGERKKEE-RERKKRRREKENKEGEEKEKRKKK 118 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGG 247 + R + G + +++ K +++ + + EE+ +R + + G Sbjct: 119 EKKE----RGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK--KRERKQVG 172 Query: 248 ERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294 E+ E+ + R+E+++ ER+E+ + E + E +K Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERK 219 Score = 37.4 bits (85), Expect = 0.017 Identities = 29/153 (18%), Positives = 69/153 (45%), Gaps = 15/153 (9%) Query: 155 KSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKA 214 +SE++E+ ++ ++ +E + E +KE R+R + + ++R E+ Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKRERE------------KERKRERG 82 Query: 215 SDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEA 274 ++ + + EE+ + ++ +G E+ E+R+ E + R+ KEE Sbjct: 83 KKEKKGERKKEERERKKRRREKENKEGEEK---EKRKKKEKKERGRTSKEGKERERKEER 139 Query: 275 SEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307 E KE E+ + R++ ++ E + ++ G Sbjct: 140 KREERKERERKKEEREKERERKERKKRERKQVG 172 Score = 35.4 bits (80), Expect = 0.064 Identities = 31/139 (22%), Positives = 60/139 (43%), Gaps = 20/139 (14%) Query: 113 GCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLH 172 G S E K + +K+E K R ++ E+E E ER + + +Q+ Sbjct: 124 GRTSKEGKERERKEERKREERKERERKKEEREKERERKER-----------KKRERKQVG 172 Query: 173 QEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVL 232 ++E+E +EKE ++R E ++ E +++ K ++ + Q + Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR------ 226 Query: 233 GGDRSLWQGAERGGGERRE 251 ++ W+ ERG ER+E Sbjct: 227 ---QTNWREKERGKRERKE 242 >gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens] Length = 1341 Score = 50.1 bits (118), Expect = 3e-06 Identities = 52/203 (25%), Positives = 85/203 (41%), Gaps = 28/203 (13%) Query: 105 ELCGTEPHGCAS-TEEKGLLLGDFKKQEAGKMRSSQ-----EVRDEEEEEVAERTHKSEV 158 EL P +S +EEKG D +K G+ RSS+ + E + AE E Sbjct: 197 ELSRHSPRKSSSISEEKGD--SDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQET 254 Query: 159 QEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE--------NGGDLQKRV 210 + +R++ R L EE+EEEE+EE + E +D Q+ E G+ RV Sbjct: 255 PSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRV 314 Query: 211 AEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEPRQE 270 + E + +++E+ V ERGG R H + + E + Sbjct: 315 KPEEMMDERPKTRSQEQEV------------LERGGRFTRSQEEARKSHLARQQQEKEMK 362 Query: 271 KEEASEREEKEVEQLEHLRDELK 293 E EE+E++ + L+++ K Sbjct: 363 TTSPLEEEEREIKSSQGLKEKSK 385 Score = 35.8 bits (81), Expect = 0.049 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 2/103 (1%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 ++ E K R + +++EEEE ER ++E + + R+ H E + E + ER+R Sbjct: 1240 ERAERAKEREKRR-KEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERD 1298 Query: 188 PMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVR 230 + D +R E G + +R ++ S + ++G R Sbjct: 1299 RGDRDRDR-ERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGR 1340 Score = 34.3 bits (77), Expect = 0.14 Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 12/97 (12%) Query: 160 EQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKET 219 E+A R + + +E++EEE+KE K E R LE ++R + D+E Sbjct: 1240 ERAERAKEREKRRKEQEEEEQKEREKEAERER-----NRQLERE---KRREHSRERDRER 1291 Query: 220 AQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHH 256 + + ++G R DR + ERG R D H Sbjct: 1292 ERERERDRGDR----DRDRERDRERGRERDRRDTKRH 1324 Score = 30.4 bits (67), Expect = 2.1 Identities = 42/185 (22%), Positives = 74/185 (40%), Gaps = 24/185 (12%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQL----HQEEDEEEEKEE 183 K+QE + R +E R+ E E A +E +++ I +G L Q E E E Sbjct: 143 KQQELLRQRLEREAREAAELEEAS----AESEDEMIHPEGVASLLPPDFQSSLERPELEL 198 Query: 184 RKRGPMETFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAE 243 + P ++ E GD K + + QA L +G++ Sbjct: 199 SRHSPRKS-----SSISEEKGDSDDEKPRKGERRSSRVRQARAA---------KLSEGSQ 244 Query: 244 RGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTET-LGEQ 302 E ++ P + + + + E+EE E EE+E ++ E DE +K E + ++ Sbjct: 245 PAEEEEDQETPSRNLRV-RADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKE 303 Query: 303 LRREG 307 + EG Sbjct: 304 FKEEG 308 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 49.7 bits (117), Expect = 3e-06 Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 10/182 (5%) Query: 126 DFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERK 185 D K+ + R S+ R + E ER E ++Q R +G RQ +E D + ++E + Sbjct: 32 DRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDR-EGERQRERERDRDRQRETER 90 Query: 186 RGPMETFEDLWQRHLENGGDLQK---RVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGA 242 E D RH E + QK R E+ D+E + +E G R DR + Sbjct: 91 ERDKERETD---RHTETDRERQKQKEREMERVRDREREK--QKEMG-RERQTDRETDRER 144 Query: 243 ERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQ 302 ER RE E E +++E +RE KE E+ + E ++ T+ ++ Sbjct: 145 ERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRKRDR 204 Query: 303 LR 304 R Sbjct: 205 QR 206 Score = 38.5 bits (88), Expect = 0.008 Identities = 40/167 (23%), Positives = 62/167 (37%), Gaps = 10/167 (5%) Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFE 193 + R + RD +E E H SE Q R R ++ D E EK+ + G + Sbjct: 23 RRRETDRERDRAKESKTEDRH-SERDRQRDR---ERNRERDRDREREKQTDREGERQRER 78 Query: 194 DL---WQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250 + QR E D ++ Q Q E + RV +R + + G ER+ Sbjct: 79 ERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRER---EKQKEMGRERQ 135 Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 D Q E E +E +E +E E+ E K+ T+ Sbjct: 136 TDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETK 182 >gi|94721321 coiled-coil domain containing 11 [Homo sapiens] Length = 514 Score = 48.9 bits (115), Expect = 6e-06 Identities = 42/165 (25%), Positives = 84/165 (50%), Gaps = 15/165 (9%) Query: 134 KMRSSQEVRDEEEEEVAERTHKSEVQ---EQAIRMQGHRQLHQEEDEEEEKEERKRGPME 190 K ++ QE R ++ + ER + + EQ + M+ ++ Q+ EE +K+++KR M Sbjct: 277 KQKAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMI 336 Query: 191 TFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250 + ++ ++L Q+R EKA +KE + E+K ++ D+ L R E R Sbjct: 337 REQKIYHKYLA-----QRREEEKAQEKEFDRILEEDKAKKLAEKDKEL-----RLEKEAR 386 Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKV 295 L + + + + ++ EA E+EE+ +EQ +H+ + LK++ Sbjct: 387 RQLVDEVMCTRKLQVQEKLQR-EAKEQEERAMEQ-KHINESLKEL 429 Score = 30.0 bits (66), Expect = 2.7 Identities = 16/52 (30%), Positives = 31/52 (59%), Gaps = 1/52 (1%) Query: 137 SSQEVRDEEEEEVAERTHKSEVQEQAIRMQ-GHRQLHQEEDEEEEKEERKRG 187 S +E+ EE+E A R ++ + ++MQ ++Q QE ++EE++ E + G Sbjct: 425 SLKELNCEEKENFARRQRLAQEYRKQLQMQIAYQQQSQEAEKEEKRREFEAG 476 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 48.1 bits (113), Expect = 1e-05 Identities = 41/167 (24%), Positives = 72/167 (43%), Gaps = 27/167 (16%) Query: 134 KMRSSQEVRDEEEEEVAERT---HKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPME 190 K S +E+R+ E E+ ER K + QE+ + R+ QE+++E EKE+ K+ ME Sbjct: 497 KQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME 556 Query: 191 TFEDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERR 250 +R E +L++ +K +KE + + +EK + E+ Sbjct: 557 K-----ERKQEKEKELER---QKEKEKELQKMKEQEKECEL----------------EKE 592 Query: 251 EDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTE 297 + +P EP EK+E+ KE E + +D + E Sbjct: 593 REKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKE 639 Score = 43.9 bits (102), Expect = 2e-04 Identities = 39/167 (23%), Positives = 71/167 (42%), Gaps = 36/167 (21%) Query: 142 RDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE 201 R EEEE E K+ E+ R+ + +++ EE ER+R E ++ E Sbjct: 465 RREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQE 524 Query: 202 NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHH 261 Q+R E+ D+E Q E+ ++L Sbjct: 525 -----QEREKEREKDRERQQ--------------------------EKEKELEKEQEKQR 553 Query: 262 QPEAEPRQEKEEASEREEKEVEQLEHLRD-----ELKKVTETLGEQL 303 + E E +QEKE+ ER++++ ++L+ +++ EL+K E L E++ Sbjct: 554 EMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI 600 Score = 38.5 bits (88), Expect = 0.008 Identities = 40/162 (24%), Positives = 67/162 (41%), Gaps = 34/162 (20%) Query: 133 GKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETF 192 G S Q+V DE+E R +SE+ R + R EE+E +E+RK E Sbjct: 430 GPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRR----EEEERRMEEQRKAACAEKL 485 Query: 193 EDLWQRHLENGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERRED 252 + L D + + EK E + + EK ER ER ++ Sbjct: 486 KRL---------DEKLGILEKQPSPEEIREREREK---------------ER---EREKE 518 Query: 253 LPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRDELKK 294 L + E E +E+++ +EKE+E+ + + E++K Sbjct: 519 LEKEQEQEREKEREKDRERQQ---EKEKELEKEQEKQREMEK 557 Score = 34.3 bits (77), Expect = 0.14 Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 9/101 (8%) Query: 128 KKQEAGKMRSSQEVRDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRG 187 +++E + R + +++E+E ER E Q++ + Q Q E E+E K+E+ Sbjct: 507 REREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEK--- 563 Query: 188 PMETFEDLWQRHLENGGDLQK-RVAEKASDKETAQFQAEEK 227 E +R E +LQK + EK + E + + EEK Sbjct: 564 -----EKELERQKEKEKELQKMKEQEKECELEKEREKLEEK 599 Score = 31.2 bits (69), Expect = 1.2 Identities = 29/168 (17%), Positives = 73/168 (43%), Gaps = 11/168 (6%) Query: 128 KKQEAGKMRSSQEVRDEEEE-EVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEE----KE 182 ++QE K R R +E+E E+ + K E+ + + ++L +++++E+E KE Sbjct: 523 QEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKE 582 Query: 183 ERKRGPMETFEDLWQRHLENGGD-----LQKRVAEKASDKETAQ-FQAEEKGVRVLGGDR 236 + K +E + + +E ++K+ +E + +KE F ++ Sbjct: 583 QEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATP 642 Query: 237 SLWQGAERGGGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQ 284 + + G + R + + Q PR ++++ ++++ +Q Sbjct: 643 VVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQ 690 Score = 30.4 bits (67), Expect = 2.1 Identities = 33/144 (22%), Positives = 58/144 (40%), Gaps = 9/144 (6%) Query: 151 ERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDLQKRV 210 ER E Q R H H ++ +E+ E P T R +++ +++ Sbjct: 910 ERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVT-----SRCIDSKEPIER-- 962 Query: 211 AEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAEP--R 268 E+ KE +E + +S + R RRE++ P +P R Sbjct: 963 PEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLR 1022 Query: 269 QEKEEASEREEKEVEQLEHLRDEL 292 KEE +R+EKE E+ E + +++ Sbjct: 1023 DMKEEREQRKEKEGEKAEKVTEKV 1046 >gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] Length = 625 Score = 47.8 bits (112), Expect = 1e-05 Identities = 64/286 (22%), Positives = 111/286 (38%), Gaps = 24/286 (8%) Query: 33 GAGERGLQWEGAGSA----PSGEASGAEPPAGDTTAAPLAPRPSKEELTRCLAEVVTEVL 88 G R L+W SA P+G AS G +A L P + + L ++ Sbjct: 272 GESLRELRWPPRASARNSCPAGSASSTTNAPGRPSALTLVPITGR---SFSLGDLSHSPQ 328 Query: 89 TVGQVQRGPCTALLHKELCGTEPHG------CASTEEKGLLLGDFKKQEAGKMRSSQ-EV 141 T V+R + L G + ++ LLL + + G+ + Sbjct: 329 TAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQWELQRVHA 388 Query: 142 RDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE 201 + E E E+ E +A Q + + EE E R++ E E+ + E Sbjct: 389 KQRREREEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAE 448 Query: 202 NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHH 261 G L++ AE+A+ ++ + +E+ ++ + L +G ER RRE Sbjct: 449 RQGLLRRERAERAAREDRLRKLQQEQNLKQR--EEGLQEGRERAEQIRRE--------RA 498 Query: 262 QPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307 Q A +Q +E +RE++E+ + E R E T ++ REG Sbjct: 499 QRAARAKQRQEGQLQREKRELSRAERARHEALLQGRTRQQRQEREG 544 >gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] Length = 627 Score = 47.8 bits (112), Expect = 1e-05 Identities = 64/286 (22%), Positives = 111/286 (38%), Gaps = 24/286 (8%) Query: 33 GAGERGLQWEGAGSA----PSGEASGAEPPAGDTTAAPLAPRPSKEELTRCLAEVVTEVL 88 G R L+W SA P+G AS G +A L P + + L ++ Sbjct: 274 GESLRELRWPPRASARNSCPAGSASSTTNAPGRPSALTLVPITGR---SFSLGDLSHSPQ 330 Query: 89 TVGQVQRGPCTALLHKELCGTEPHG------CASTEEKGLLLGDFKKQEAGKMRSSQ-EV 141 T V+R + L G + ++ LLL + + G+ + Sbjct: 331 TAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQWELQRVHA 390 Query: 142 RDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE 201 + E E E+ E +A Q + + EE E R++ E E+ + E Sbjct: 391 KQRREREEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAE 450 Query: 202 NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHH 261 G L++ AE+A+ ++ + +E+ ++ + L +G ER RRE Sbjct: 451 RQGLLRRERAERAAREDRLRKLQQEQNLKQR--EEGLQEGRERAEQIRRE--------RA 500 Query: 262 QPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307 Q A +Q +E +RE++E+ + E R E T ++ REG Sbjct: 501 QRAARAKQRQEGQLQREKRELSRAERARHEALLQGRTRQQRQEREG 546 >gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] Length = 627 Score = 47.8 bits (112), Expect = 1e-05 Identities = 64/286 (22%), Positives = 111/286 (38%), Gaps = 24/286 (8%) Query: 33 GAGERGLQWEGAGSA----PSGEASGAEPPAGDTTAAPLAPRPSKEELTRCLAEVVTEVL 88 G R L+W SA P+G AS G +A L P + + L ++ Sbjct: 274 GESLRELRWPPRASARNSCPAGSASSTTNAPGRPSALTLVPITGR---SFSLGDLSHSPQ 330 Query: 89 TVGQVQRGPCTALLHKELCGTEPHG------CASTEEKGLLLGDFKKQEAGKMRSSQ-EV 141 T V+R + L G + ++ LLL + + G+ + Sbjct: 331 TAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEELLLLEQRAAAHGQWELQRVHA 390 Query: 142 RDEEEEEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLE 201 + E E E+ E +A Q + + EE E R++ E E+ + E Sbjct: 391 KQRREREEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAE 450 Query: 202 NGGDLQKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHH 261 G L++ AE+A+ ++ + +E+ ++ + L +G ER RRE Sbjct: 451 RQGLLRRERAERAAREDRLRKLQQEQNLKQR--EEGLQEGRERAEQIRRE--------RA 500 Query: 262 QPEAEPRQEKEEASEREEKEVEQLEHLRDELKKVTETLGEQLRREG 307 Q A +Q +E +RE++E+ + E R E T ++ REG Sbjct: 501 QRAARAKQRQEGQLQREKRELSRAERARHEALLQGRTRQQRQEREG 546 >gi|148746183 ubiquitin specific protease 35 [Homo sapiens] Length = 1018 Score = 47.8 bits (112), Expect = 1e-05 Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 5/83 (6%) Query: 117 TEEKGLLLGDFKKQEAGKMRSSQEVRDEEEEEVAERTHKSEV--QEQAIRMQGHRQLHQE 174 T L + +EAG S +E + EEE ERT K EV +E++ R +G R+ +E Sbjct: 652 TPPTSLYIEGLDSKEAGGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEE 711 Query: 175 EDEEEEKEER---KRGPMETFED 194 +EEEEK E+ K E ED Sbjct: 712 VEEEEEKVEKETEKEAEQEKEED 734 Score = 31.2 bits (69), Expect = 1.2 Identities = 22/70 (31%), Positives = 31/70 (44%), Gaps = 2/70 (2%) Query: 233 GGDRSLWQGAERG--GGERREDLPHHHHHHHQPEAEPRQEKEEASEREEKEVEQLEHLRD 290 GG S + ER G E R + E +EKEE E EE++VE+ Sbjct: 668 GGQSSQEERIEREEEGKEERTEKEEVGEEEESTRGEGEREKEEEVEEEEEKVEKETEKEA 727 Query: 291 ELKKVTETLG 300 E +K ++LG Sbjct: 728 EQEKEEDSLG 737 >gi|205277396 dynactin 1 isoform 4 [Homo sapiens] Length = 1139 Score = 47.4 bits (111), Expect = 2e-05 Identities = 69/279 (24%), Positives = 112/279 (40%), Gaps = 44/279 (15%) Query: 44 AGSAPSGEASGAEP--PAGDTTAAPLAPRP---------------SKEELTRCLAEVVTE 86 +GSA +GE S +EP PA AAP+ P P +EE R + E Sbjct: 36 SGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEE 95 Query: 87 VLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEE 146 L +++R A L KEL E H E+ ++Q+A R +E R E + Sbjct: 96 KLETLRLKRAEDKAKL-KEL---EKHK-IQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 150 Query: 147 EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDL 206 E A + ++E A +++ EE+ E + +E L Sbjct: 151 E--ALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEA--------------L 194 Query: 207 QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAE 266 ++RV E +D E + + EEKG L Q E+ R +D E + Sbjct: 195 KERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNA--RLKDALVRMRDLSSSEKQ 252 Query: 267 PRQEKEEASEREEKEVE----QLEHLRDELKKVTETLGE 301 + ++ E++ +E+E Q E L++EL + T+ E Sbjct: 253 EHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 291 >gi|205277392 dynactin 1 isoform 3 [Homo sapiens] Length = 1253 Score = 47.4 bits (111), Expect = 2e-05 Identities = 69/279 (24%), Positives = 112/279 (40%), Gaps = 44/279 (15%) Query: 44 AGSAPSGEASGAEP--PAGDTTAAPLAPRP---------------SKEELTRCLAEVVTE 86 +GSA +GE S +EP PA AAP+ P P +EE R + E Sbjct: 150 SGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEE 209 Query: 87 VLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEE 146 L +++R A L KEL E H E+ ++Q+A R +E R E + Sbjct: 210 KLETLRLKRAEDKAKL-KEL---EKHK-IQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 264 Query: 147 EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDL 206 E A + ++E A +++ EE+ E + +E L Sbjct: 265 E--ALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEA--------------L 308 Query: 207 QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAE 266 ++RV E +D E + + EEKG L Q E+ R +D E + Sbjct: 309 KERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNA--RLKDALVRMRDLSSSEKQ 366 Query: 267 PRQEKEEASEREEKEVE----QLEHLRDELKKVTETLGE 301 + ++ E++ +E+E Q E L++EL + T+ E Sbjct: 367 EHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 405 >gi|13259508 dynactin 1 isoform 2 [Homo sapiens] Length = 1144 Score = 47.4 bits (111), Expect = 2e-05 Identities = 69/279 (24%), Positives = 112/279 (40%), Gaps = 44/279 (15%) Query: 44 AGSAPSGEASGAEP--PAGDTTAAPLAPRP---------------SKEELTRCLAEVVTE 86 +GSA +GE S +EP PA AAP+ P P +EE R + E Sbjct: 36 SGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEE 95 Query: 87 VLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEE 146 L +++R A L KEL E H E+ ++Q+A R +E R E + Sbjct: 96 KLETLRLKRAEDKAKL-KEL---EKHK-IQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 150 Query: 147 EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDL 206 E A + ++E A +++ EE+ E + +E L Sbjct: 151 E--ALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEA--------------L 194 Query: 207 QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAE 266 ++RV E +D E + + EEKG L Q E+ R +D E + Sbjct: 195 KERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNA--RLKDALVRMRDLSSSEKQ 252 Query: 267 PRQEKEEASEREEKEVE----QLEHLRDELKKVTETLGE 301 + ++ E++ +E+E Q E L++EL + T+ E Sbjct: 253 EHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 291 >gi|13259510 dynactin 1 isoform 1 [Homo sapiens] Length = 1278 Score = 47.4 bits (111), Expect = 2e-05 Identities = 69/279 (24%), Positives = 112/279 (40%), Gaps = 44/279 (15%) Query: 44 AGSAPSGEASGAEP--PAGDTTAAPLAPRP---------------SKEELTRCLAEVVTE 86 +GSA +GE S +EP PA AAP+ P P +EE R + E Sbjct: 170 SGSASAGELSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLRAQVRDLEE 229 Query: 87 VLTVGQVQRGPCTALLHKELCGTEPHGCASTEEKGLLLGDFKKQEAGKMRSSQEVRDEEE 146 L +++R A L KEL E H E+ ++Q+A R +E R E + Sbjct: 230 KLETLRLKRAEDKAKL-KEL---EKHK-IQLEQVQEWKSKMQEQQADLQRRLKEARKEAK 284 Query: 147 EEVAERTHKSEVQEQAIRMQGHRQLHQEEDEEEEKEERKRGPMETFEDLWQRHLENGGDL 206 E A + ++E A +++ EE+ E + +E L Sbjct: 285 E--ALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEA--------------L 328 Query: 207 QKRVAEKASDKETAQFQAEEKGVRVLGGDRSLWQGAERGGGERREDLPHHHHHHHQPEAE 266 ++RV E +D E + + EEKG L Q E+ R +D E + Sbjct: 329 KERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNA--RLKDALVRMRDLSSSEKQ 386 Query: 267 PRQEKEEASEREEKEVE----QLEHLRDELKKVTETLGE 301 + ++ E++ +E+E Q E L++EL + T+ E Sbjct: 387 EHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDE 425 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.130 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,833,471 Number of Sequences: 37866 Number of extensions: 863043 Number of successful extensions: 19494 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 406 Number of HSP's successfully gapped in prelim test: 637 Number of HSP's that attempted gapping in prelim test: 8369 Number of HSP's gapped (non-prelim): 5537 length of query: 307 length of database: 18,247,518 effective HSP length: 102 effective length of query: 205 effective length of database: 14,385,186 effective search space: 2948963130 effective search space used: 2948963130 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.