Guide to the Human Genome
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Search of human proteins with 169213453

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169213453 PREDICTED: hypothetical protein LOC646862 [Homo
sapiens]
         (329 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169214080 PREDICTED: hypothetical protein LOC646862 [Homo sap...   699   0.0  
gi|169214500 PREDICTED: hypothetical protein LOC646862 [Homo sap...   699   0.0  
gi|169213453 PREDICTED: hypothetical protein LOC646862 [Homo sap...   699   0.0  
gi|239752655 PREDICTED: hypothetical protein [Homo sapiens]           106   3e-23
gi|239747208 PREDICTED: hypothetical protein [Homo sapiens]           106   3e-23
gi|239740999 PREDICTED: hypothetical protein [Homo sapiens]           105   6e-23
gi|153252110 ring finger protein 183 [Homo sapiens]                    69   6e-12
gi|27436925 synoviolin 1 isoform a [Homo sapiens]                      57   2e-08
gi|27436927 synoviolin 1 isoform b [Homo sapiens]                      56   5e-08
gi|84993742 tripartite motif-containing 71 [Homo sapiens]              55   9e-08
gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase...    54   1e-07
gi|150170670 piccolo isoform 2 [Homo sapiens]                          52   7e-07
gi|150378539 piccolo isoform 1 [Homo sapiens]                          52   7e-07
gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]      51   2e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    50   2e-06
gi|39812378 RAN binding protein 9 [Homo sapiens]                       50   3e-06
gi|226442736 ring finger protein 222 [Homo sapiens]                    50   4e-06
gi|239745703 PREDICTED: ring finger protein 222 [Homo sapiens]         50   4e-06
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    50   4e-06
gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transfera...    49   6e-06
gi|239756718 PREDICTED: ring finger protein 222 [Homo sapiens]         49   8e-06
gi|239751213 PREDICTED: ring finger protein 222 [Homo sapiens]         49   8e-06
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    48   1e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    48   1e-05
gi|56605981 tripartite motif-containing 72 [Homo sapiens]              48   1e-05
gi|153791514 tripartite motif-containing 32 [Homo sapiens]             48   1e-05
gi|153792582 tripartite motif-containing 32 [Homo sapiens]             48   1e-05
gi|47132519 Ras association and pleckstrin homology domains 1 is...    47   2e-05
gi|22027541 programmed cell death 7 [Homo sapiens]                     47   2e-05
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                47   3e-05

>gi|169214080 PREDICTED: hypothetical protein LOC646862 [Homo
           sapiens]
          Length = 329

 Score =  699 bits (1803), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MPCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPAS 60
           MPCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPAS
Sbjct: 1   MPCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPAS 60

Query: 61  PVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR 120
           PVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR
Sbjct: 61  PVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR 120

Query: 121 RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLR 180
           RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLR
Sbjct: 121 RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLR 180

Query: 181 LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA 240
           LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA
Sbjct: 181 LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA 240

Query: 241 PAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAERTLD 300
           PAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAERTLD
Sbjct: 241 PAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAERTLD 300

Query: 301 RRSDGTWGTEAGPGWAPWPRGARRLWGSQ 329
           RRSDGTWGTEAGPGWAPWPRGARRLWGSQ
Sbjct: 301 RRSDGTWGTEAGPGWAPWPRGARRLWGSQ 329


>gi|169214500 PREDICTED: hypothetical protein LOC646862 [Homo
           sapiens]
          Length = 329

 Score =  699 bits (1803), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MPCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPAS 60
           MPCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPAS
Sbjct: 1   MPCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPAS 60

Query: 61  PVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR 120
           PVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR
Sbjct: 61  PVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR 120

Query: 121 RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLR 180
           RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLR
Sbjct: 121 RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLR 180

Query: 181 LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA 240
           LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA
Sbjct: 181 LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA 240

Query: 241 PAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAERTLD 300
           PAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAERTLD
Sbjct: 241 PAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAERTLD 300

Query: 301 RRSDGTWGTEAGPGWAPWPRGARRLWGSQ 329
           RRSDGTWGTEAGPGWAPWPRGARRLWGSQ
Sbjct: 301 RRSDGTWGTEAGPGWAPWPRGARRLWGSQ 329


>gi|169213453 PREDICTED: hypothetical protein LOC646862 [Homo
           sapiens]
          Length = 329

 Score =  699 bits (1803), Expect = 0.0
 Identities = 329/329 (100%), Positives = 329/329 (100%)

Query: 1   MPCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPAS 60
           MPCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPAS
Sbjct: 1   MPCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPAS 60

Query: 61  PVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR 120
           PVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR
Sbjct: 61  PVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR 120

Query: 121 RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLR 180
           RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLR
Sbjct: 121 RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLR 180

Query: 181 LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA 240
           LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA
Sbjct: 181 LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA 240

Query: 241 PAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAERTLD 300
           PAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAERTLD
Sbjct: 241 PAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAERTLD 300

Query: 301 RRSDGTWGTEAGPGWAPWPRGARRLWGSQ 329
           RRSDGTWGTEAGPGWAPWPRGARRLWGSQ
Sbjct: 301 RRSDGTWGTEAGPGWAPWPRGARRLWGSQ 329


>gi|239752655 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score =  106 bits (264), Expect = 3e-23
 Identities = 86/243 (35%), Positives = 106/243 (43%), Gaps = 40/243 (16%)

Query: 18  SGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVECLICVSSFDGVFKL 77
           S P SP S  +PRSP               G+PGS  +   ASP+EC IC S +D +FK 
Sbjct: 23  SMPRSPSSAGSPRSP---------------GTPGSERV---ASPLECSICFSGYDNIFKT 64

Query: 78  PKRLDCGHVFCLECLARLSLAT---AGGGNAVACPVCRAPTRLAPRRGLPALPTQSGLLP 134
           PK L C HVFCLECLARL+ A      GG AV CP CR PT + P  G PAL T   L  
Sbjct: 65  PKELSCTHVFCLECLARLAAAQPVGRPGGEAVPCPFCRQPTAVPP-AGAPALCTSRQL-- 121

Query: 135 RDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRK-------ARAPPPPPPLRLGRPLSR 187
             AR P   +           L  +P P  PG            + P  PP+    P  R
Sbjct: 122 -QARMPAHLRREEPVWLEGTKLCCQPLPTTPGREPGFVCVDVGLSKPAEPPVPARDPAPR 180

Query: 188 RLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSG-------PPRPQLVALA 240
           R  LA   W          LV+A L++      + +  A  +G       PPRP   + A
Sbjct: 181 RGRLAR-CWARCRDWRRMALVSALLLMLFCVALWPVQCALKTGNLRCLPLPPRPPATSTA 239

Query: 241 PAP 243
            +P
Sbjct: 240 ASP 242


>gi|239747208 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score =  106 bits (264), Expect = 3e-23
 Identities = 86/243 (35%), Positives = 106/243 (43%), Gaps = 40/243 (16%)

Query: 18  SGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVECLICVSSFDGVFKL 77
           S P SP S  +PRSP               G+PGS  +   ASP+EC IC S +D +FK 
Sbjct: 23  SMPRSPSSAGSPRSP---------------GTPGSERV---ASPLECSICFSGYDNIFKT 64

Query: 78  PKRLDCGHVFCLECLARLSLAT---AGGGNAVACPVCRAPTRLAPRRGLPALPTQSGLLP 134
           PK L C HVFCLECLARL+ A      GG AV CP CR PT + P  G PAL T   L  
Sbjct: 65  PKELSCTHVFCLECLARLAAAQPVGRPGGEAVPCPFCRQPTAVPP-AGAPALCTSRQL-- 121

Query: 135 RDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRK-------ARAPPPPPPLRLGRPLSR 187
             AR P   +           L  +P P  PG            + P  PP+    P  R
Sbjct: 122 -QARMPAHLRREEPVWLEGTKLCCQPLPTTPGREPGFVCVDVGLSKPAEPPVPARDPAPR 180

Query: 188 RLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSG-------PPRPQLVALA 240
           R  LA   W          LV+A L++      + +  A  +G       PPRP   + A
Sbjct: 181 RGRLAR-CWARCRDWRRMALVSALLLMLFCVALWPVQCALKTGNLRCLPLPPRPPATSTA 239

Query: 241 PAP 243
            +P
Sbjct: 240 ASP 242


>gi|239740999 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score =  105 bits (262), Expect = 6e-23
 Identities = 86/243 (35%), Positives = 105/243 (43%), Gaps = 40/243 (16%)

Query: 18  SGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVECLICVSSFDGVFKL 77
           S P SP S  +PRSP               G+PGS  +   ASP+EC IC S +D +FK 
Sbjct: 23  SMPRSPSSAGSPRSP---------------GTPGSERV---ASPLECSICFSGYDNIFKT 64

Query: 78  PKRLDCGHVFCLECLARLSLAT---AGGGNAVACPVCRAPTRLAPRRGLPALPTQSGLLP 134
           PK L C HVFCLECLARL+ A      GG AV CP CR PT + P  G PAL T   L  
Sbjct: 65  PKELSCTHVFCLECLARLAAAQPVGRPGGEAVPCPFCRQPTAVPP-AGAPALCTSRQL-- 121

Query: 135 RDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRK-------ARAPPPPPPLRLGRPLSR 187
             AR P   +           L  +P P  PG            + P  PP     P  R
Sbjct: 122 -QARMPAHLRREEPVWLEGTKLCCQPLPTTPGREPGFVCVDVGLSKPAEPPAPARDPAPR 180

Query: 188 RLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSG-------PPRPQLVALA 240
           R  LA   W          LV+A L++      + +  A  +G       PPRP   + A
Sbjct: 181 RGRLAR-CWARCRDWRRMALVSALLLMLFCVALWPVQCALKTGNLRCLPLPPRPPATSTA 239

Query: 241 PAP 243
            +P
Sbjct: 240 ASP 242


>gi|153252110 ring finger protein 183 [Homo sapiens]
          Length = 192

 Score = 68.9 bits (167), Expect = 6e-12
 Identities = 33/71 (46%), Positives = 43/71 (60%), Gaps = 1/71 (1%)

Query: 63  ECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPRRG 122
           EC +C + F+  F  PK LDC H FC+ECLA LSL T      + CP+CR PT LA  + 
Sbjct: 12  ECPVCWNPFNNTFHTPKMLDCCHSFCVECLAHLSLVTP-ARRRLLCPLCRQPTVLASGQP 70

Query: 123 LPALPTQSGLL 133
           +  LPT + +L
Sbjct: 71  VTDLPTDTAML 81


>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
          Length = 616

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 70/243 (28%), Positives = 88/243 (36%), Gaps = 68/243 (27%)

Query: 55  ILPPASPVECL----ICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPV 110
           + P A+P E      +C+   + +    KRL C H+F   CL       +       CP 
Sbjct: 275 LYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLR------SWFQRQQTCPT 328

Query: 111 CRA-------PTRLAPR-----RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYL 158
           CR        P +  P      +G P  P    LLP+    P            +GLL  
Sbjct: 329 CRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFP------------QGLL-- 374

Query: 159 RPPPPPPG-----PRKARAPPPPPPLRLGR---PLSRRLSLASPAWVFNAAVALAVLVAA 210
             PP PPG     P     PP PPP   G    P S   +L+ P+         A   AA
Sbjct: 375 --PPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAALSRPS-------GAATTTAA 425

Query: 211 GLVVSGVYIFFLIPHATSSGPPRPQLVALAPAPGFSWFPPRPPP--GSPWAP--AWTPRP 266
           G   +          AT+SGP         PAPGF    P PPP  G P  P  A+ P P
Sbjct: 426 GTSATAA-------SATASGPGSGSAPEAGPAPGF----PFPPPWMGMPLPPPFAFPPMP 474

Query: 267 TGP 269
             P
Sbjct: 475 VPP 477


>gi|27436927 synoviolin 1 isoform b [Homo sapiens]
          Length = 617

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 69/244 (28%), Positives = 88/244 (36%), Gaps = 69/244 (28%)

Query: 55  ILPPASPVECL----ICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPV 110
           + P A+P E      +C+   + +    KRL C H+F   CL       +       CP 
Sbjct: 275 LYPDATPEELQAMDNVCIICREEMVTGAKRLPCNHIFHTSCLR------SWFQRQQTCPT 328

Query: 111 CRA-------PTRLAPR-----RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYL 158
           CR        P +  P      +G P  P    LLP+    P            +GLL  
Sbjct: 329 CRMDVLRASLPAQSPPPPEPADQGPPPAPHPPPLLPQPPNFP------------QGLL-- 374

Query: 159 RPPPPPPG-----PRKARAPPPPPPLRLGR----PLSRRLSLASPAWVFNAAVALAVLVA 209
             PP PPG     P     PP PPP   G     P +   +L+ P+         A   A
Sbjct: 375 --PPFPPGMFPLWPPMGPFPPVPPPPSSGEAVAPPSTSAAALSRPS-------GAATTTA 425

Query: 210 AGLVVSGVYIFFLIPHATSSGPPRPQLVALAPAPGFSWFPPRPPP--GSPWAP--AWTPR 265
           AG   +          AT+SGP         PAPGF    P PPP  G P  P  A+ P 
Sbjct: 426 AGTSATAA-------SATASGPGSGSAPEAGPAPGF----PFPPPWMGMPLPPPFAFPPM 474

Query: 266 PTGP 269
           P  P
Sbjct: 475 PVPP 478


>gi|84993742 tripartite motif-containing 71 [Homo sapiens]
          Length = 868

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 71/266 (26%), Positives = 89/266 (33%), Gaps = 56/266 (21%)

Query: 22  SPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVECLICVSSFDGVFKLPKRL 81
           SP  LS+  S S    Q       G G PG+      A  +  L C+             
Sbjct: 21  SPAPLSSNSSASSSSSQTSTSSGGGGGGPGAA-----ARRLHVLPCL------------- 62

Query: 82  DCGHVFCLECLARLSLATAGGGNA-----VACPVCRAPTRLAPRRGLPALPTQSGLL--- 133
              H FC  CL    L  AGGG A     + CPVC     LA   G+ ALP+ + LL   
Sbjct: 63  ---HAFCRPCLEAHRLPAAGGGAAGEPLKLRCPVCDQKVVLAEAAGMDALPSSAFLLSNL 119

Query: 134 ------------PRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLRL 181
                       P++ RA          + R    +  P      P   +AP PP P R 
Sbjct: 120 LDAVVATADEPPPKNGRAGAPAGAGGHSNHRHHAHHAHPRASASAPPLPQAPQPPAPSRS 179

Query: 182 --GRP-------LSRRLSLASPAWVFNAAVALAV----LVAAGLVVSGVYIFFLIPHATS 228
             G P       L RR    S     NAA +  +     +    V +   +     H   
Sbjct: 180 APGGPAASPSALLLRRPHGCSSCDEGNAASSRCLDCQEHLCDNCVRAHQRVRLTKDHYIE 239

Query: 229 SGPPRPQLVALAPAPGFSWFPPRPPP 254
            GPP P   A A   G    PP P P
Sbjct: 240 RGPPGPGAAAAAQQLGLG--PPFPGP 263


>gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4
           [Homo sapiens]
          Length = 456

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 52/160 (32%), Positives = 65/160 (40%), Gaps = 24/160 (15%)

Query: 160 PPPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYI 219
           PPPPPP P    APPPP     G P  + L + +       ++++  L  + L  SG   
Sbjct: 7   PPPPPPPPPPLAAPPPPGASAKGPPARKLLFMCT------LSLSVTYLCYSLLGGSGSLQ 60

Query: 220 FFLI----PHATSSGPPRPQLVALAPAP---GFSWFPPRPPP------GSPWAPAWTPRP 266
           F L     P A +  PP P   +L P P   G    PP PPP      G P  P   P  
Sbjct: 61  FPLALQESPGAAAEPPPSPPPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEPPEQPAA 120

Query: 267 TGPDLDTALP---GTAEDA-LEPEAGPEDPAEAERTLDRR 302
            G D    LP   G A+DA L     P +   A+  L  R
Sbjct: 121 PGTD-GWGLPSGGGGAQDAWLRTPLAPSEMITAQSALPER 159


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 44/130 (33%), Positives = 58/130 (44%), Gaps = 30/130 (23%)

Query: 160  PPPPPPGPRKARAPPPPPPLRLGRPLS--------RRLSLASPAW----VFNAAVAL--- 204
            PPPPPP P     PPPPPP  L  P S        ++L++ASP      +F+A   L   
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT 2465

Query: 205  AVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALAPA-------PGFSWFPPRPPPGSP 257
            AVL + GL V+ +         T++ PP P   +  P+       P  S  P  P P  P
Sbjct: 2466 AVLRSNGLPVTRI--------CTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP 2517

Query: 258  WAPAWTPRPT 267
              P  T +PT
Sbjct: 2518 QLPTTTQKPT 2527



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 62/284 (21%), Positives = 100/284 (35%), Gaps = 36/284 (12%)

Query: 63  ECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPT-RLAPRR 121
           EC   V S  G    P   +     CL C  + +L    GG+    P    P  + AP  
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL----GGDLAPVPSSPQPKLKTAPVT 667

Query: 122 GLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPR-----KARAPPPP 176
              A+   S   P+  +  P +  + + D  +     +PPP    P       A+A  PP
Sbjct: 668 TTSAVSKSS---PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 177 PPLRLGRPLSRRLSLASPAWVFNAAVA------------LAVLVAAGLVVSGVYIFFLIP 224
               L +P   +   + P+    A VA               LV++    +   I     
Sbjct: 725 EADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783

Query: 225 HATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDA-- 282
            + +     P L   +  P  S FPP     SP+     PRP       + PG + ++  
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQS-FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKG 842

Query: 283 ---LEPEAGPEDPAEAERTLDRRSDGTWGTEAGPGWAPWPRGAR 323
              ++P    E+P +A+  +  + D     +  P  +P P G R
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPD----AKPMPKGSPTPPGPR 882



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 66/282 (23%), Positives = 90/282 (31%), Gaps = 40/282 (14%)

Query: 16  QGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVECLICVSSFDGVF 75
           QG G         P+S S  + ++ + +  G G P  GP   P +               
Sbjct: 223 QGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA------------ 270

Query: 76  KLPKRLDCGHVFCLECLARLSLATAGGGNAV--ACPVCRAPTRLAPRRGLPAL--PTQSG 131
           KLP + D           +   A    G +V  + P    P    P  G P    P    
Sbjct: 271 KLPLQRDASR-------PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK 323

Query: 132 LLPRDARAPPSRQGSVR-FDRRRGLLYLRPPPPPPGPRKARAPPPPPPLRLGRPLSRRLS 190
             P  A+ P    G  +   ++ G   ++PP  PPG  K    PP  PL   +P +++  
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGT--VKPPVQPPGTTK----PPAQPLGPAKPPAQQTG 377

Query: 191 LASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALAPAPGFSWFPP 250
              P+       ALA     G            P     G P+P    LA  PG     P
Sbjct: 378 SEKPSSEQPGPKALAQPPGVG-KTPAQQPGPAKPPTQQVGTPKP----LAQQPGLQ--SP 430

Query: 251 RPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDP 292
              PG    P   P P       A PG        + GP  P
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTS---AQQTGPTKP 469



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 19/88 (21%)

Query: 114 PTRLAPRRGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAP 173
           P +  P++  PA P      P  A+ P  + GS +           PPP  PGP K    
Sbjct: 476 PAKPPPQQPGPAKPPPQQ--PGSAKPPSQQPGSTK-----------PPPQQPGPAKPSPQ 522

Query: 174 PP----PPPLRLG--RPLSRRLSLASPA 195
            P    PP  + G  +P +++ S A P+
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPS 550


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 44/130 (33%), Positives = 58/130 (44%), Gaps = 30/130 (23%)

Query: 160  PPPPPPGPRKARAPPPPPPLRLGRPLS--------RRLSLASPAW----VFNAAVAL--- 204
            PPPPPP P     PPPPPP  L  P S        ++L++ASP      +F+A   L   
Sbjct: 2406 PPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETT 2465

Query: 205  AVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALAPA-------PGFSWFPPRPPPGSP 257
            AVL + GL V+ +         T++ PP P   +  P+       P  S  P  P P  P
Sbjct: 2466 AVLRSNGLPVTRI--------CTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP 2517

Query: 258  WAPAWTPRPT 267
              P  T +PT
Sbjct: 2518 QLPTTTQKPT 2527



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 62/284 (21%), Positives = 100/284 (35%), Gaps = 36/284 (12%)

Query: 63  ECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPT-RLAPRR 121
           EC   V S  G    P   +     CL C  + +L    GG+    P    P  + AP  
Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL----GGDLAPVPSSPQPKLKTAPVT 667

Query: 122 GLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPR-----KARAPPPP 176
              A+   S   P+  +  P +  + + D  +     +PPP    P       A+A  PP
Sbjct: 668 TTSAVSKSS---PQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 177 PPLRLGRPLSRRLSLASPAWVFNAAVA------------LAVLVAAGLVVSGVYIFFLIP 224
               L +P   +   + P+    A VA               LV++    +   I     
Sbjct: 725 EADSLSKPAPPK-EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV 783

Query: 225 HATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDA-- 282
            + +     P L   +  P  S FPP     SP+     PRP       + PG + ++  
Sbjct: 784 QSQAEEKTTPPLKTDSAKPSQS-FPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKG 842

Query: 283 ---LEPEAGPEDPAEAERTLDRRSDGTWGTEAGPGWAPWPRGAR 323
              ++P    E+P +A+  +  + D     +  P  +P P G R
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPD----AKPMPKGSPTPPGPR 882



 Score = 33.1 bits (74), Expect = 0.35
 Identities = 66/282 (23%), Positives = 90/282 (31%), Gaps = 40/282 (14%)

Query: 16  QGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVECLICVSSFDGVF 75
           QG G         P+S S  + ++ + +  G G P  GP   P +               
Sbjct: 223 QGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA------------ 270

Query: 76  KLPKRLDCGHVFCLECLARLSLATAGGGNAV--ACPVCRAPTRLAPRRGLPAL--PTQSG 131
           KLP + D           +   A    G +V  + P    P    P  G P    P    
Sbjct: 271 KLPLQRDASR-------PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEK 323

Query: 132 LLPRDARAPPSRQGSVR-FDRRRGLLYLRPPPPPPGPRKARAPPPPPPLRLGRPLSRRLS 190
             P  A+ P    G  +   ++ G   ++PP  PPG  K    PP  PL   +P +++  
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGT--VKPPVQPPGTTK----PPAQPLGPAKPPAQQTG 377

Query: 191 LASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALAPAPGFSWFPP 250
              P+       ALA     G            P     G P+P    LA  PG     P
Sbjct: 378 SEKPSSEQPGPKALAQPPGVG-KTPAQQPGPAKPPTQQVGTPKP----LAQQPGLQ--SP 430

Query: 251 RPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDP 292
              PG    P   P P       A PG        + GP  P
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTS---AQQTGPTKP 469



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 19/88 (21%)

Query: 114 PTRLAPRRGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAP 173
           P +  P++  PA P      P  A+ P  + GS +           PPP  PGP K    
Sbjct: 476 PAKPPPQQPGPAKPPPQQ--PGSAKPPSQQPGSTK-----------PPPQQPGPAKPSPQ 522

Query: 174 PP----PPPLRLG--RPLSRRLSLASPA 195
            P    PP  + G  +P +++ S A P+
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPS 550


>gi|170016069 zinc finger, CCHC domain containing 2 [Homo sapiens]
          Length = 1178

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 30/70 (42%), Positives = 36/70 (51%), Gaps = 3/70 (4%)

Query: 120 RRGLPALPTQSGLLPRDARAPPS--RQGSVRFDRRRGLLYLRPPPPPP-GPRKARAPPPP 176
           R  LP  PT     P +A  P +  R G+    RRR      PPPPPP GP +   PPPP
Sbjct: 3   RMKLPLKPTHPAEPPPEAEEPEADARPGAKAPSRRRRDCRPPPPPPPPAGPSRGPLPPPP 62

Query: 177 PPLRLGRPLS 186
           PP  LG P++
Sbjct: 63  PPRGLGPPVA 72


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 76/295 (25%), Positives = 100/295 (33%), Gaps = 47/295 (15%)

Query: 14   APQGSGPSSPGSLSAPRSPS------RGEDQEEEEEEEGDGSPGSGPILPPASPVECLIC 67
            +P+G GP++P    AP  P+      +G        +     P + P  P  SP      
Sbjct: 995  SPKG-GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT--- 1050

Query: 68   VSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAV----ACPVCRAPTRLAPRRGL 123
                     LPK                +L +  GG A       P   A T  +P+ G 
Sbjct: 1051 --------PLPKGAPT--------TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG- 1093

Query: 124  PALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPP---PPLR 180
            PA P+  G     A  PPS +G +     +G     P   PP P+   A PPP   P   
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKG-APTTPAATPPSPKGGLATPPPKGAPTTP 1152

Query: 181  LGRPLSRRLSLAS--PAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVA 238
               P S +  LA+  P        A       GL           P AT   PP P+   
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT---PPSPKGGL 1209

Query: 239  LAPAPGFSWFPPRPPPGSPWAPAWTPRPTG-PDLDTALPGTAEDALEPEAGPEDP 292
              P+P  +   P   P SP     TP P G P    A P +      P+ GP  P
Sbjct: 1210 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS------PKGGPATP 1258



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 77/294 (26%), Positives = 98/294 (33%), Gaps = 30/294 (10%)

Query: 15   PQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVECLICVSSFDGV 74
            P  + PS  GS +A   P               GSP + P LP  +P      + S  G 
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP-LPKGAPTTPAATLPSPKGG 1070

Query: 75   FKLPKRLDCGHVFCLECLARLSLATAG---GGNAV----ACPVCRAPTRLAPRRGLPALP 127
               P          L+       AT     GG A       P+  A T  +P+ GL A P
Sbjct: 1071 PATPS---------LKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL-ATP 1120

Query: 128  TQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPP---PPLRLGRP 184
               G     A  PPS +G +     +G     P   PP P+   A PPP   P      P
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAP-TTPAATPPSPKGGLATPPPKGAPTTPAATP 1179

Query: 185  LSRRLSLA--SPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALAPA 242
             S +  LA  SP        A       GL           P   ++ PP P+     P+
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG---APTTPAATPPSPKGGLATPS 1236

Query: 243  P-GFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDAL--EPEAGPEDPA 293
            P G    P   PP     PA  P    P    A P + +  L   P  G  +PA
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 79/307 (25%), Positives = 108/307 (35%), Gaps = 54/307 (17%)

Query: 18   SGPSSP-GSLSAPRSPSRGEDQEEEEE--EEGDGSPGSG----PILPPASPVECLICVSS 70
            +GP +P G+LS+P SP       E     +    SP +     P  P  +P    +   S
Sbjct: 815  AGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLS 874

Query: 71   FDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPR----RGLPAL 126
              GV   PK      V  L    +   AT     A A  +  +  + A      +G+PA 
Sbjct: 875  PKGVTLPPKETPTPSVVNLP-FPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933

Query: 127  PTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPP---PPGPRKARAPPPP---PPLR 180
            P+  G     A  PPS +G       +      P PP   PP P+   A P P   P   
Sbjct: 934  PSPKGAPTPPAATPPSPKGGPATPSPK----WAPTPPAATPPSPKGGPATPSPKGAPTPP 989

Query: 181  LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALA 240
               P S +   A+P+    A    AV   +             P  + +  P P+  +  
Sbjct: 990  AATPPSPKGGPATPS-PKGAPTPPAVTPPS-------------PKGSPAATPFPKGASTP 1035

Query: 241  PAPGFSWFPPRP---------PPGSPWAPAWT-PRPTG----PDLDTALPGTAEDALEPE 286
            PA      PP P         P G+P  PA T P P G    P L  A    A     P+
Sbjct: 1036 PAA----TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091

Query: 287  AGPEDPA 293
             GP  P+
Sbjct: 1092 GGPATPS 1098



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 52/202 (25%), Positives = 67/202 (33%), Gaps = 43/202 (21%)

Query: 109  PVCRAPTRLAPRRGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPR 168
            P   A T  +P+ GL A P+  G     A  PPS +G +     +G     P   PP P+
Sbjct: 1195 PTTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPK 1252

Query: 169  KARAPPPP---PPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPH 225
               A PPP   P      P S +  LA+P                     G       P+
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPH------------------KGA------PN 1288

Query: 226  ATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTG-----------PDLDTA 274
                 PP P+       P  +  PP   P SP     TP P G           P     
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348

Query: 275  LPGTAEDALEPEAGPEDPAEAE 296
            LP T   +   + GP  P+  E
Sbjct: 1349 LPATTPSS---KGGPTTPSSKE 1367



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 74/291 (25%), Positives = 105/291 (36%), Gaps = 56/291 (19%)

Query: 14   APQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVEC------LIC 67
            AP+G GP++P S   P  P+      +E       +  S P   PA+P          + 
Sbjct: 1451 APKG-GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509

Query: 68   VSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPRRGLPALP 127
             SS   V   P             L++ + AT     A+  P    P   +P++  PA+P
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP---SPKK-TPAIP 1565

Query: 128  T--QSGLLP--RDARAPPSRQGSVRFDRRRGLLYLRPP------------PP---PPGPR 168
            T  ++   P  ++A +PP+   S           L PP            PP   PP P 
Sbjct: 1566 TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625

Query: 169  KARAPPPP------PPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFL 222
            K  A P P      PP+    P S + S  SPA V     A     + GL          
Sbjct: 1626 KGPATPAPKGTPTSPPV---TPSSLKDSPTSPASVTCKMGATVPQASKGL---------- 1672

Query: 223  IPHATSSGPPRPQLVALAPAPGFS---WFPPRPPPGSPWAPAWTPRPTGPD 270
                   GP   + V +APAP  +     P R  P +  + A +P P  PD
Sbjct: 1673 ---PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP-PICPD 1719



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 27/100 (27%), Positives = 39/100 (39%), Gaps = 8/100 (8%)

Query: 224  PHATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTG-PDLDTALPGTAEDA 282
            P   ++ PP P+     P+P ++  PP   P SP     TP P G P    A P +    
Sbjct: 940  PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS---- 995

Query: 283  LEPEAGPEDPAEAERTLDRRSDGTWGTEAGPGWAPWPRGA 322
              P+ GP  P+                +  P   P+P+GA
Sbjct: 996  --PKGGPATPSPKGAPTPPAVTPP-SPKGSPAATPFPKGA 1032



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 9/68 (13%)

Query: 232  PRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPED 291
            P+P+  +++ AP        PP   P AP+  P PT P     LP +    LE  + P  
Sbjct: 1783 PKPESASVSAAPS-------PPVSLPLAPS--PVPTLPPKQQFLPSSPGLVLESPSKPLA 1833

Query: 292  PAEAERTL 299
            PA+ +  L
Sbjct: 1834 PADEDELL 1841



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 42/191 (21%), Positives = 65/191 (34%), Gaps = 48/191 (25%)

Query: 3    CPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPV 62
            CP P     S+ P  +         AP  P + +  +  + ++   SP  GP+ PP S  
Sbjct: 1717 CPDPSAKNGSKGPLST------VAPAPLLPVQKDSSKTAKGKDASHSP-KGPLAPPESKA 1769

Query: 63   ECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPRRG 122
               +  ++F+ V   P+                +  +A     V+ P+  +P    P + 
Sbjct: 1770 STPLTAAAFEKVLPKPES---------------ASVSAAPSPPVSLPLAPSPVPTLPPK- 1813

Query: 123  LPALPTQSGLL---PRDARAPPSRQGSVRFDRRRGLLYLRPPPP-------------PPG 166
               LP+  GL+   P    AP              LL L PP P              P 
Sbjct: 1814 QQFLPSSPGLVLESPSKPLAPADED---------ELLPLIPPEPISGGVPFQSVLVNMPT 1864

Query: 167  PRKARAPPPPP 177
            P+ A  P P P
Sbjct: 1865 PKSAGIPVPTP 1875


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 45/127 (35%), Positives = 55/127 (43%), Gaps = 9/127 (7%)

Query: 159 RPPPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVY 218
           +PPPPPP  ++ +    PPP     P+S  +  A PA    ++ A +    AG    G  
Sbjct: 4   QPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAA 63

Query: 219 IFFLIPHATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGT 278
              L+ H     PP P   A  P P     PP PPP S  APA  P P  P L  A PG 
Sbjct: 64  AAALLLHPP---PPPPPATAAPPPPP----PPPPPPASAAAPASGP-PAPPGL-AAGPGP 114

Query: 279 AEDALEP 285
           A  A  P
Sbjct: 115 AGGAPTP 121



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 30/68 (44%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 114 PTRLAPRRG--LPALPTQS-GLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKA 170
           P  LAP  G  LPA P  S G  P  A +P    G          L L PPPPPP    A
Sbjct: 24  PAALAPVSGVVLPAPPAVSAGSSP--AGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAA 81

Query: 171 RAPPPPPP 178
             PPPPPP
Sbjct: 82  PPPPPPPP 89


>gi|226442736 ring finger protein 222 [Homo sapiens]
          Length = 220

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 47/178 (26%), Positives = 64/178 (35%), Gaps = 54/178 (30%)

Query: 45  EGDGSPGSGPILPPASPVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGG- 103
           EG+    SG         EC +C   F  +    + L CGHVFC +CL +  L+T   G 
Sbjct: 3   EGESKDSSGS--------ECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQ 54

Query: 104 --NAVACPVCRAPTRLAPRR------------------GLPALPTQSGL---LPRDARAP 140
               + CP+CR  T L+ +                   GLP++P    L    P  A +P
Sbjct: 55  VQRTLVCPICRYVTFLSKKSSRWPSMLDKSSQTLAVPVGLPSVPPLDSLGHTNPLAASSP 114

Query: 141 PSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVF 198
             R                   PPPG  +   PP  P      PL    SL   + +F
Sbjct: 115 AWR-------------------PPPGQAR---PPGSPGQSAQLPLDLLPSLPRESQIF 150


>gi|239745703 PREDICTED: ring finger protein 222 [Homo sapiens]
          Length = 220

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 47/178 (26%), Positives = 64/178 (35%), Gaps = 54/178 (30%)

Query: 45  EGDGSPGSGPILPPASPVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGG- 103
           EG+    SG         EC +C   F  +    + L CGHVFC +CL +  L+T   G 
Sbjct: 3   EGESKDSSGS--------ECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQ 54

Query: 104 --NAVACPVCRAPTRLAPRR------------------GLPALPTQSGL---LPRDARAP 140
               + CP+CR  T L+ +                   GLP++P    L    P  A +P
Sbjct: 55  VQRTLVCPICRYVTFLSKKSSRWPSMLDKSSQTLAVPVGLPSVPPLDSLGHTNPLAASSP 114

Query: 141 PSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVF 198
             R                   PPPG  +   PP  P      PL    SL   + +F
Sbjct: 115 AWR-------------------PPPGQAR---PPGSPGQSAQLPLDLLPSLPRESQIF 150


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 76/295 (25%), Positives = 94/295 (31%), Gaps = 67/295 (22%)

Query: 2   PCPRPFWLRHSRA---------PQGSGPSS-----PGSLSAPRSPSRGEDQEEEEEE--- 44
           P PRPF  + S +         P+G G        P  +   R  +   ++EEEEEE   
Sbjct: 619 PAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSS 678

Query: 45  --EGDGSPGSGPILPPASPVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGG 102
             E   S G GP      P+ C +C                G   CL      ++A  GG
Sbjct: 679 PGEDSSSLGGGP--SRRGPLPCPLCSRE-------------GACSCLPLERGDAVAGWGG 723

Query: 103 GNAVACPVCRAPTRLAPRRGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPP 162
             A+ CP         P     +L  + G L     APP+       D   G     P  
Sbjct: 724 HPALGCP--------HPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAA--APQY 773

Query: 163 PPPGPRKARAPPPPPPLRLGRPLS------------RRLSLASPAWVFNAAVALAVLVAA 210
           P  GP  A  PPPPPP     P +              LS   P    +           
Sbjct: 774 PGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPE 833

Query: 211 GLVVSGVYIFFLIPHATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPR 265
           G    G         A   G PRP+     P PG     PRPPP     P   PR
Sbjct: 834 GAFPGG-------GAAEEEGVPRPRAPPEPPDPG----APRPPPDPGPLPLPGPR 877



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 20/45 (44%), Positives = 24/45 (53%), Gaps = 7/45 (15%)

Query: 140 PPSRQGSVRFDRRRGLLYL------RPPPPPPGPRKARAPPPPPP 178
           PP+++ S   D +  L YL      RPPPPPP PR    P P PP
Sbjct: 423 PPAQRPSAS-DLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPP 466



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 28/91 (30%), Positives = 40/91 (43%), Gaps = 16/91 (17%)

Query: 5    RPFWLRHSRAPQGSGPSSPGSLSAPRSPSR-GEDQEEEEEE-EGDGSPGS-----GPILP 57
            RP W     A  G+     G   AP      GED++E+EEE E   +PG+     GP   
Sbjct: 1279 RPPW---EGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRA 1335

Query: 58   PASPVECLICVSSFD------GVFKLPKRLD 82
             A+PV  ++  +  D      G+ K P+  D
Sbjct: 1336 RAAPVPVVVSSADADAARPLRGLLKSPRGAD 1366



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 19/59 (32%), Positives = 22/59 (37%), Gaps = 5/59 (8%)

Query: 230 GPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAG 288
           G   PQ     P P      P PPP  P APA       P    A PG+   +  P+ G
Sbjct: 767 GAAAPQYPGRGPPPA-----PPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPG 820


>gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transferase
           4 [Homo sapiens]
          Length = 1039

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 68/246 (27%), Positives = 85/246 (34%), Gaps = 47/246 (19%)

Query: 109 PVCRAPTRLAPRRGLPALPTQSGLL--------PRDARAPPSRQG---SVRFDRRRGLLY 157
           P   AP R  P+   PA P Q G          PRD   P   +    + R  R   L  
Sbjct: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFL 508

Query: 158 LRPPPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGV 217
            R PPP P   +   PPP   +   RP  +R S  +PA             A      GV
Sbjct: 509 GRAPPPRPAVEQ---PPPKVYVTRVRP-GQRASPRAPA-----------PRAPWPPFPGV 553

Query: 218 YIFFL-IPHATSSGPPRPQLVALAPAPGFSWFPPRPPP------GSPWAPAWTPRPTGPD 270
           ++    +P      PPRP         G     PRPP       G     A T  P  P 
Sbjct: 554 FLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPT 613

Query: 271 LDTAL-----PGTAEDALEPEAGPEDPAEAERTLDRRSDGTWGTE---------AGPGWA 316
           +D+ L     P T+  +L   +GP+ P E E   +   DG  G E         AGP   
Sbjct: 614 VDSNLSSEARPVTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPALG 673

Query: 317 PWPRGA 322
            W   A
Sbjct: 674 RWREDA 679



 Score = 29.3 bits (64), Expect = 5.0
 Identities = 15/30 (50%), Positives = 18/30 (60%), Gaps = 3/30 (10%)

Query: 22  SPGSLSAPRSPSRGEDQEEEEEEEGDGSPG 51
           S   +S P+ P  GE   EEEE E DG+PG
Sbjct: 630 SLSQVSGPQLPGEGE---EEEEGEDDGAPG 656


>gi|239756718 PREDICTED: ring finger protein 222 [Homo sapiens]
          Length = 220

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 11/79 (13%)

Query: 45  EGDGSPGSGPILPPASPVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGG- 103
           EG+    SG         EC +C   F  +    + L CGHVFC +CL +  L+T   G 
Sbjct: 3   EGESKDSSGS--------ECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQ 54

Query: 104 --NAVACPVCRAPTRLAPR 120
               + CP+CR  T L+ +
Sbjct: 55  VQRTLVCPICRYVTFLSKK 73


>gi|239751213 PREDICTED: ring finger protein 222 [Homo sapiens]
          Length = 220

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 11/79 (13%)

Query: 45  EGDGSPGSGPILPPASPVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGG- 103
           EG+    SG         EC +C   F  +    + L CGHVFC +CL +  L+T   G 
Sbjct: 3   EGESKDSSGS--------ECPVCYEKFRDLEGASRTLSCGHVFCHDCLVKYLLSTRVDGQ 54

Query: 104 --NAVACPVCRAPTRLAPR 120
               + CP+CR  T L+ +
Sbjct: 55  VQRTLVCPICRYVTFLSKK 73


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 60/192 (31%), Positives = 67/192 (34%), Gaps = 64/192 (33%)

Query: 101 GGGNAVACPVCR-APTRLAPRRGLPALPT----QSGLLPRDARA------PPSRQGSVRF 149
           GG  AV   + R AP    P RG P  P      SG  P  AR       PPSR  +   
Sbjct: 263 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAA- 321

Query: 150 DRRRGLLYLRPPPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVA 209
                      PPPPP  R + A PPPPP R+  P         PA              
Sbjct: 322 -----------PPPPPPSRPSVAVPPPPPNRMYPP-------PPPA-------------- 349

Query: 210 AGLVVSGVYIFFLIPHATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTG- 268
                        +P +  SGPP P    L   P     PP PPP  P  P   P P G 
Sbjct: 350 -------------LPSSAPSGPPPPPPSVLGVGP---VAPPPPPPPPP--PPGPPPPPGL 391

Query: 269 -PDLDTALPGTA 279
             D D  +P TA
Sbjct: 392 PSDGDHQVPTTA 403



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 41/151 (27%), Positives = 48/151 (31%), Gaps = 46/151 (30%)

Query: 161 PPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIF 220
           PPPPP  R    PPPPPP   G P        +P    + A                   
Sbjct: 277 PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRA------------------- 317

Query: 221 FLIPHATSSGPP--RPQLVALAPAPGFSWFPPRPP---------------------PGSP 257
              P A    PP  RP  VA+ P P    +PP PP                     P +P
Sbjct: 318 ---PTAAPPPPPPSRPS-VAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAP 373

Query: 258 WAPAWTPRPTGPDLDTALPGTAEDALEPEAG 288
             P   P P GP     LP   +  +   AG
Sbjct: 374 PPPPPPPPPPGPPPPPGLPSDGDHQVPTTAG 404



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 37/137 (27%), Positives = 46/137 (33%), Gaps = 56/137 (40%)

Query: 159 RPPPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVY 218
           R  PPPP P +   PPPPPP                                        
Sbjct: 274 RQAPPPPPPSRGGPPPPPPP---------------------------------------- 293

Query: 219 IFFLIPHATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGT 278
                PH  +SGPP P      PA G    PP PP  +P A    P P+ P +  A+P  
Sbjct: 294 -----PH--NSGPPPP------PARGRG-APPPPPSRAPTAAPPPPPPSRPSV--AVPPP 337

Query: 279 AEDALEPEAGPEDPAEA 295
             + + P   P  P+ A
Sbjct: 338 PPNRMYPPPPPALPSSA 354


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 72/274 (26%), Positives = 98/274 (35%), Gaps = 40/274 (14%)

Query: 14  APQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVECLICVSSFDG 73
           +P  SGPS+ G+  AP  PS+ + +  +       +P      P   P+      SS   
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL------SSSPL 304

Query: 74  VFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLAPRRGLPALPTQSGLL 133
               P          L+  A  +L      +++ C +   P  LAP    P+ P     L
Sbjct: 305 ATPSPSA-------ALQSQAPPTLPATPHSSSLTCQLA-TPLPLAPPS--PSAPPSLQTL 354

Query: 134 PRDARAPPSRQ----GSVRFDRRRGLLYLRP-----PPPPPGPRKARAPP---PPPPLRL 181
           P     PPS+     GS         L   P      PPP  P     PP   PP P   
Sbjct: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP--- 411

Query: 182 GRPLSRRLS-LASPAWVFNAAVALAVLVAA-----GLVVSGVYIFFLIPHATSSGPPRPQ 235
             P S  LS LA+P+     A+A+ +L A         V   +     P  + S  P  Q
Sbjct: 412 --PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 469

Query: 236 LVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGP 269
                 AP     PP PP   P +P+ TP P  P
Sbjct: 470 APPSLAAPPLQ-VPPSPPASPPMSPSATPPPQAP 502



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 61/192 (31%), Positives = 76/192 (39%), Gaps = 40/192 (20%)

Query: 138 RAPPSRQGSVRFDRRRGLLYLRPPPPPP-----GPRK--ARAP-PPPPPLRLGRPLSRRL 189
           + PPS   S      R     RPP P P     GPR   A AP PPPPP R     S   
Sbjct: 572 QVPPSPPASPTLQAPR-----RPPTPGPDTSVSGPRLTLALAPGPPPPPSR-----SPSS 621

Query: 190 SLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGPPRPQLVALAPAPGFSWFP 249
           +L+ P    +++ A +         SG         A +S PP  +L A  PA   +W  
Sbjct: 622 TLSGPDLAGHSSSATSTPEELRGYDSGPE-----GGAAASPPPDAELAACHPA---AWSR 673

Query: 250 PRPPP----GSPWAPAWTPRPTGPDLDTALPGTAED--ALEPEAGPEDPAEAERTLD-RR 302
              PP    G+P AP   P  TG       PG+A+    +    GPE    A   LD   
Sbjct: 674 GPAPPLAFRGAPGAPLPWPPATG-------PGSADGLCTIYETEGPESATPAPGALDPGP 726

Query: 303 SDGTWGTEAGPG 314
           S GT G +A  G
Sbjct: 727 SPGTSGGKAAAG 738



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 83/334 (24%), Positives = 105/334 (31%), Gaps = 44/334 (13%)

Query: 11  HSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPILPPASPVECLICVSS 70
           HS  P  S P SP +   P++P        +       SP   P+  P+      + V  
Sbjct: 378 HSFLP--SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 435

Query: 71  FDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLA-PRRGLPALPTQ 129
               F  P        F       +S +        A P  +AP  LA P   +P  P  
Sbjct: 436 LQAPFSPPPSPPVQAPFSPPASPPVSPS--------ATPPSQAPPSLAAPPLQVPPSPPA 487

Query: 130 SGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAP----PPPPPLRLGR-P 184
           S  +   A  PP     +        L L  PPP   P  A  P    P PP    G+ P
Sbjct: 488 SPPMSPSATPPPQAPPPLAAPP----LQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543

Query: 185 LSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGP-PRPQLVALAPAP 243
            S   SL           A  VL A  L V           A    P P P      P  
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603

Query: 244 GFSWFPPRPPPGSPWAPAWTPRPT--GPDL---DTALPGTAEDALEPEAGPEDPAEAERT 298
             +  P  PPP     P+ +P  T  GPDL    ++   T E+    ++GPE  A A   
Sbjct: 604 TLALAPGPPPP-----PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 658

Query: 299 LDRR----SDGTWGTEAGPGWA---------PWP 319
            D          W     P  A         PWP
Sbjct: 659 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 692



 Score = 35.0 bits (79), Expect = 0.092
 Identities = 52/182 (28%), Positives = 63/182 (34%), Gaps = 39/182 (21%)

Query: 134 PRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKA-------RAPPPPPPLR------ 180
           P  A A  SR         R     RP PP  GPRK+           P P  R      
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231

Query: 181 --LGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATS-SGPPRPQ-L 236
             L RP SR LS        ++A  L+    +G    G       P A +    P+P+ L
Sbjct: 232 GGLQRPASRSLS--------SSATPLSSPARSGPSARGT------PRAPAHPSQPKPKGL 277

Query: 237 VALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGPEDPAEAE 296
            AL P       P   PP    APA  P  + P L T  P  A  +  P   P  P  + 
Sbjct: 278 QALRP-------PQVTPPRKDAAPALGPLSSSP-LATPSPSAALQSQAPPTLPATPHSSS 329

Query: 297 RT 298
            T
Sbjct: 330 LT 331



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 28/110 (25%), Positives = 34/110 (30%), Gaps = 22/110 (20%)

Query: 161 PPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIF 220
           PP P  P   +  P PP      P     SL SP                   +   + F
Sbjct: 342 PPSPSAPPSLQTLPSPPATP---PSQATTSLGSPT------------------LQATHSF 380

Query: 221 FLIPHATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPD 270
              P  +    P PQ       P     PP PP   P +P  TP P  P+
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQ-APPSPPASPPLSPLATPSPQAPN 429


>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 5/55 (9%)

Query: 62  VECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTR 116
           + C +C+  FD     P   +CGH FC  CL R++   A  G  V CP C+APTR
Sbjct: 12  LSCPLCLQLFDA----PVTAECGHSFCRACLGRVAGEPAADG-TVLCPCCQAPTR 61


>gi|153791514 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 62  VECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRL 117
           +EC IC+ SF      PK L CGH  C +CL +L    A   N V CP C   TR+
Sbjct: 18  LECPICMESFTEEQLRPKLLHCGHTICRQCLEKL---LASSINGVRCPFCSKITRI 70


>gi|153792582 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 62  VECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRL 117
           +EC IC+ SF      PK L CGH  C +CL +L    A   N V CP C   TR+
Sbjct: 18  LECPICMESFTEEQLRPKLLHCGHTICRQCLEKL---LASSINGVRCPFCSKITRI 70


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 42/119 (35%), Positives = 46/119 (38%), Gaps = 14/119 (11%)

Query: 158 LRPPPPPPGPRKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGV 217
           L PPPPPP P     PPPPPPL    P     S  S A +F     +  L  A    SG 
Sbjct: 628 LPPPPPPPPPPPPPPPPPPPPL----PSQSAPSAGSAAPMFVKYSTITRLQNAS-QHSGA 682

Query: 218 YIFFLIPHATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPA-----WTPRPTGPDL 271
                 P    S   +PQ+  L P  G    PP PPP  P  P        P P  P L
Sbjct: 683 LFKPPTPPVMQSQSVKPQI--LVPPNGV--VPPPPPPPPPPTPGSAMAQLKPAPCAPSL 737



 Score = 37.0 bits (84), Expect = 0.024
 Identities = 28/96 (29%), Positives = 38/96 (39%), Gaps = 21/96 (21%)

Query: 109 PVCRAPTRLAPR-----RGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPP 163
           P+   P  +AP+     +  P     S  +P     PP  + S+ F           PPP
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVF-----------PPP 930

Query: 164 PPGPRKARAPPPPP-----PLRLGRPLSRRLSLASP 194
           PP P  A  PPPPP     P + G P  +    +SP
Sbjct: 931 PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSP 966



 Score = 36.2 bits (82), Expect = 0.041
 Identities = 46/155 (29%), Positives = 59/155 (38%), Gaps = 38/155 (24%)

Query: 113 APTRLAPRRGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPP-PPPPGPRKAR 171
           A  +L P    P+LP  S        APP     ++  + + +  + PP PPPP P  A 
Sbjct: 724 AMAQLKPAPCAPSLPQFS--------APPP---PLKIHQVQHITQVAPPTPPPPPPIPAP 772

Query: 172 APPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVSGVYIFFLIPHATSSGP 231
            PP  PP    +PL     +  PA      VA  V  AA             P  T   P
Sbjct: 773 LPPQAPP----KPL-----VTIPAPTSTKTVAPVVTQAAP------------PTPTPPVP 811

Query: 232 PRPQLVALAPAPGFSWFPPRPP-PGSPWAPAWTPR 265
           P  +     PA   S+ PP PP P  P  P   P+
Sbjct: 812 PAKK----QPAFPASYIPPSPPTPPVPVPPPTLPK 842



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 72/312 (23%), Positives = 96/312 (30%), Gaps = 55/312 (17%)

Query: 2   PCPRPFWLRHSRAPQGSGPSSPGSLSAPRSPSRGEDQEEEEEEEGDGSPGSGPI---LPP 58
           P P P        P    PS P   SAP  P +    +   +      P   PI   LPP
Sbjct: 717 PPPTPGSAMAQLKPAPCAPSLP-QFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPP 775

Query: 59  ASPVECLICVSSFDGVFKLPKRLDCGHVFCLECLARLSLATAGGGNAVACPVCRAPTRLA 118
            +P + L+ +                        A  S  T       A P    P  + 
Sbjct: 776 QAPPKPLVTIP-----------------------APTSTKTVAPVVTQAAPPTPTPP-VP 811

Query: 119 PRRGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKAR--APPPP 176
           P +  PA P  +  +P     PP                  P PPP  P++    A PPP
Sbjct: 812 PAKKQPAFP--ASYIPPSPPTPPV-----------------PVPPPTLPKQQSFCAKPPP 852

Query: 177 PPLRLGRPLSRRLSLASPAWVFNAAVALAVL--VAAGLVVSGVYIFFLIPHATSSGPPRP 234
            PL     + ++++   P      A+    L  V A +           P    S  P P
Sbjct: 853 SPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP 912

Query: 235 QLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTG---PDLDTALPGTAEDALEPEAGPED 291
                 P P  S   P PPP    AP   P PT    PD  +  PG          G + 
Sbjct: 913 SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPD-KSGSPGKKTSKTSSPGGKKP 971

Query: 292 PAEAERTLDRRS 303
           P   +R    +S
Sbjct: 972 PPTPQRNSSIKS 983



 Score = 28.9 bits (63), Expect = 6.6
 Identities = 42/187 (22%), Positives = 61/187 (32%), Gaps = 30/187 (16%)

Query: 109  PVCRAPTRLAPRRGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPP----- 163
            P   +PT    + G P   T     P   + PP+ Q +       G  +  P  P     
Sbjct: 943  PPTASPT--PDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000

Query: 164  -----PPG----PRKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVV 214
                 PP     P K   PPP  P + G+     ++L  P  +    V+    V +G   
Sbjct: 1001 VSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNL--PGVLQQGCVSAKAPVLSGRGK 1058

Query: 215  SGVYIFFLIPHATSSGPPRPQLVALAP------------APGFSWFPPRPPPGSPWAPAW 262
              V  F   P  +   PP P+     P            +P  +   P+P   S  +   
Sbjct: 1059 DSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKK 1118

Query: 263  TPRPTGP 269
             P PT P
Sbjct: 1119 APPPTRP 1125


>gi|22027541 programmed cell death 7 [Homo sapiens]
          Length = 485

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 40/119 (33%), Positives = 45/119 (37%), Gaps = 13/119 (10%)

Query: 160 PPPPPPGPRKARAPPPP-PPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVS--- 215
           PPP PP P     PPPP P      PL +R      A        LA+   A    S   
Sbjct: 15  PPPQPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPGASAPFLQPPLALQPRASAEASRGG 74

Query: 216 -GVYIFFLIPHATSSGPPRPQLVALAPAPGFSWF----PPRPPPGSPWAPAWTPRPTGP 269
            G   F+ +P      PP PQ     P PG        PP P PG PW+P W   P  P
Sbjct: 75  GGAGAFYPVPPPPLPPPP-PQC---RPFPGTDAGERPRPPPPGPGPPWSPRWPEAPPPP 129



 Score = 32.7 bits (73), Expect = 0.46
 Identities = 29/99 (29%), Positives = 37/99 (37%), Gaps = 10/99 (10%)

Query: 230 GPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEAGP 289
           GPP PQ     P P   +  P PP  SP  P   P+  GP      PG +   L+P    
Sbjct: 13  GPPPPQ-----PPPPAPFGCPPPPLPSPAFPPPLPQRPGP-----FPGASAPFLQPPLAL 62

Query: 290 EDPAEAERTLDRRSDGTWGTEAGPGWAPWPRGARRLWGS 328
           +  A AE +      G +     P   P P   R   G+
Sbjct: 63  QPRASAEASRGGGGAGAFYPVPPPPLPPPPPQCRPFPGT 101



 Score = 31.6 bits (70), Expect = 1.0
 Identities = 17/36 (47%), Positives = 19/36 (52%), Gaps = 5/36 (13%)

Query: 159 RPPPPPPGPRKARAP-----PPPPPLRLGRPLSRRL 189
           RP PPPPGP    +P     PPPP   LG    +RL
Sbjct: 106 RPRPPPPGPGPPWSPRWPEAPPPPADVLGDAALQRL 141



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 31/85 (36%), Positives = 32/85 (37%), Gaps = 15/85 (17%)

Query: 119 PRRGLPALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPP-PPGPRKAR------ 171
           P    P L     L PR A A  SR G        G  Y  PPPP PP P + R      
Sbjct: 49  PGASAPFLQPPLALQPR-ASAEASRGGG-----GAGAFYPVPPPPLPPPPPQCRPFPGTD 102

Query: 172 --APPPPPPLRLGRPLSRRLSLASP 194
               P PPP   G P S R   A P
Sbjct: 103 AGERPRPPPPGPGPPWSPRWPEAPP 127


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 39/121 (32%), Positives = 42/121 (34%), Gaps = 29/121 (23%)

Query: 160 PPPPPPGP----RKARAPPPPPPLRLGRPLSRRLSLASPAWVFNAAVALAVLVAAGLVVS 215
           PPPPPP P      A  PPPPPP  L    ++ L  A P        A+A          
Sbjct: 421 PPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMA---------- 470

Query: 216 GVYIFFLIPHATSSGPPRPQLVAL-----APAPGFSWFPPRPP--PGSPWAPAWTPRPTG 268
                   P A    PP P           P PG    PP PP  PG  W P   P P  
Sbjct: 471 --------PPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLL 522

Query: 269 P 269
           P
Sbjct: 523 P 523



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 24/59 (40%), Positives = 25/59 (42%), Gaps = 10/59 (16%)

Query: 124 PALPTQSGLLPRDARAPPSRQGSVRFDRRRGLLYLRPPPPPPGPRKARAPPPPPPLRLG 182
           P LP    + P     PP   GS  F          PPPPPP P     PPPPPPL  G
Sbjct: 461 PPLPGLGAMAPPAPPLPPPLPGSCEF---------LPPPPPPLPGLG-CPPPPPPLLPG 509



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 2/59 (3%)

Query: 222 LIPHATSSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAE 280
           L+P +++  PP P    L P+ G    P  PPP  P        P  P L   LPG+ E
Sbjct: 429 LLPGSSAEPPPPPPPPPL-PSVGAKALPTAPPP-PPLPGLGAMAPPAPPLPPPLPGSCE 485



 Score = 28.5 bits (62), Expect = 8.6
 Identities = 24/65 (36%), Positives = 26/65 (40%), Gaps = 4/65 (6%)

Query: 228 SSGPPRPQLVALAPAPGFSWFPPRPPPGSPWAPAWTPRPTGPDLDTALPGTAEDALEPEA 287
           +S PP P    L P       PP PPP  P   A    PT P     LPG    A+ P A
Sbjct: 418 ASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGA-KALPTAPP-PPPLPGLG--AMAPPA 473

Query: 288 GPEDP 292
            P  P
Sbjct: 474 PPLPP 478


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.139    0.464 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,811,737
Number of Sequences: 37866
Number of extensions: 1679240
Number of successful extensions: 34997
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 573
Number of HSP's successfully gapped in prelim test: 1200
Number of HSP's that attempted gapping in prelim test: 17844
Number of HSP's gapped (non-prelim): 11562
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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