Guide to the Human Genome
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Search of human proteins with 169210488

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10
(U3 small nucleolar ribonucleoprotein) [Homo sapiens]
         (213 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3...   438   e-123
gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3...   435   e-122
gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3...   435   e-122
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]                  238   3e-63
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...   140   1e-33
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...   140   1e-33
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    51   6e-07
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]                  50   2e-06
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ...    47   2e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    46   3e-05
gi|4504487 histidine rich calcium binding protein precursor [Hom...    45   6e-05
gi|21735415 centromere protein B [Homo sapiens]                        44   8e-05
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                44   1e-04
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 44   1e-04
gi|4503257 death-domain associated protein isoform a [Homo sapiens]    44   1e-04
gi|215422388 death-domain associated protein isoform a [Homo sap...    44   1e-04
gi|215422366 death-domain associated protein isoform b [Homo sap...    44   1e-04
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...    44   1e-04
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    43   2e-04
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...    43   2e-04
gi|61175239 transcription elongation factor A (SII)-like 5 [Homo...    42   3e-04
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          42   4e-04
gi|210032580 SET domain containing 1B [Homo sapiens]                   42   4e-04
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                42   5e-04
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     42   5e-04
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]     42   5e-04
gi|87299628 biorientation of chromosomes in cell division 1-like...    42   5e-04
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...    42   5e-04
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...    42   5e-04
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...    42   5e-04

>gi|169210488 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score =  438 bits (1126), Expect = e-123
 Identities = 213/213 (100%), Positives = 213/213 (100%)

Query: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60
           MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV
Sbjct: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60

Query: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120
           SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS
Sbjct: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120

Query: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHD 180
           IIDEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHD
Sbjct: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHD 180

Query: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213
           DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL
Sbjct: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213


>gi|169210281 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score =  435 bits (1119), Expect = e-122
 Identities = 212/213 (99%), Positives = 212/213 (99%)

Query: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60
           MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV
Sbjct: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60

Query: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120
           SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS
Sbjct: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120

Query: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHD 180
           IIDEKFFQLSEMEAYLENREKEEERKDDNDDES KSSRNVNNKDFFDPVESDEDIASDHD
Sbjct: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHD 180

Query: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213
           DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL
Sbjct: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213


>gi|169210051 PREDICTED: similar to M-phase phosphoprotein 10 (U3
           small nucleolar ribonucleoprotein) [Homo sapiens]
          Length = 213

 Score =  435 bits (1119), Expect = e-122
 Identities = 212/213 (99%), Positives = 212/213 (99%)

Query: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60
           MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV
Sbjct: 1   MRADPWLRCYWGRTWTRVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEV 60

Query: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120
           SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS
Sbjct: 61  SDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKS 120

Query: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHD 180
           IIDEKFFQLSEMEAYLENREKEEERKDDNDDES KSSRNVNNKDFFDPVESDEDIASDHD
Sbjct: 121 IIDEKFFQLSEMEAYLENREKEEERKDDNDDESGKSSRNVNNKDFFDPVESDEDIASDHD 180

Query: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213
           DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL
Sbjct: 181 DELGSNKMMKLLKKKQKKEAFLKCEYFETSFTL 213


>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
          Length = 681

 Score =  238 bits (607), Expect = 3e-63
 Identities = 130/201 (64%), Positives = 148/201 (73%), Gaps = 27/201 (13%)

Query: 25  VELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRK 84
           + L  ESEEQE EEDGSE E   +EDLEDL EEEEVSDMG D+PE+G++A NSSK +LRK
Sbjct: 104 ISLLPESEEQEREEDGSEIEADDKEDLEDL-EEEEVSDMGNDDPEMGERAENSSKSDLRK 162

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
           SPVFSDEDSDLDFDISKLEQQSKVQN G GKPREKSI+D+KFF+LSEMEAYLEN EKEEE
Sbjct: 163 SPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEE 222

Query: 145 RKDDNDDE--------------------------SVKSSRNVNNKDFFDPVESDEDIASD 178
           RKDDND+E                          S KSSRN+  KDFFDPVESDEDI + 
Sbjct: 223 RKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFFDPVESDEDITNV 282

Query: 179 HDDELGSNKMMKLLKKKQKKE 199
           HDDEL SNK    + +++ +E
Sbjct: 283 HDDELDSNKEDDEIAEEEAEE 303


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score =  140 bits (352), Expect = 1e-33
 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)

Query: 63  MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122
           MGGDNPEV ++A NSSKF+  KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI 
Sbjct: 1   MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59

Query: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPV-------ESDEDI 175
           DEKFFQLSEMEAYLENR++   ++ D DD+  +S  +   K+    V       E+ ED 
Sbjct: 60  DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119

Query: 176 ASDHDDELGSNKMMKLLKKKQKK 198
              H  +  S+++    KK+Q+K
Sbjct: 120 GVSHVKK-NSDEVKSSFKKRQEK 141



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 3/122 (2%)

Query: 22  WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78
           W+  E   E EE  Q+ EE   E E   QE+ E +QE+EE      +   E  +K     
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           K   ++  ++  E+     +    EQ+ K+Q       R++  + E+  +L + E  ++ 
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549

Query: 139 RE 140
           +E
Sbjct: 550 QE 551



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 26/130 (20%), Positives = 57/130 (43%), Gaps = 3/130 (2%)

Query: 15  WTRVADPWQIVELGEESEEQ--ECEEDGSETETGGQEDLEDLQ-EEEEVSDMGGDNPEVG 71
           W +     ++ E+ ++ EE+  E EE   E E   QE  E +Q +EE++ +         
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489

Query: 72  KKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSE 131
           K  +   K   ++  ++  E+   + +    EQ+ K+Q        ++  + ++  ++ E
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549

Query: 132 MEAYLENREK 141
            E  L+  E+
Sbjct: 550 QEVRLQELEE 559


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score =  140 bits (352), Expect = 1e-33
 Identities = 79/143 (55%), Positives = 99/143 (69%), Gaps = 9/143 (6%)

Query: 63  MGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSII 122
           MGGDNPEV ++A NSSKF+  KSPV SDEDSDLDF I+KLEQQSKV+N GHGKPREKSI 
Sbjct: 1   MGGDNPEVSERA-NSSKFDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIA 59

Query: 123 DEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPV-------ESDEDI 175
           DEKFFQLSEMEAYLENR++   ++ D DD+  +S  +   K+    V       E+ ED 
Sbjct: 60  DEKFFQLSEMEAYLENRKRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDA 119

Query: 176 ASDHDDELGSNKMMKLLKKKQKK 198
              H  +  S+++    KK+Q+K
Sbjct: 120 GVSHVKK-NSDEVKSSFKKRQEK 141



 Score = 33.5 bits (75), Expect = 0.14
 Identities = 30/122 (24%), Positives = 54/122 (44%), Gaps = 3/122 (2%)

Query: 22  WQIVELGEESEE--QECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-PEVGKKARNSS 78
           W+  E   E EE  Q+ EE   E E   QE+ E +QE+EE      +   E  +K     
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           K   ++  ++  E+     +    EQ+ K+Q       R++  + E+  +L + E  ++ 
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549

Query: 139 RE 140
           +E
Sbjct: 550 QE 551



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 26/130 (20%), Positives = 57/130 (43%), Gaps = 3/130 (2%)

Query: 15  WTRVADPWQIVELGEESEEQ--ECEEDGSETETGGQEDLEDLQ-EEEEVSDMGGDNPEVG 71
           W +     ++ E+ ++ EE+  E EE   E E   QE  E +Q +EE++ +         
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489

Query: 72  KKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSE 131
           K  +   K   ++  ++  E+   + +    EQ+ K+Q        ++  + ++  ++ E
Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQE 549

Query: 132 MEAYLENREK 141
            E  L+  E+
Sbjct: 550 QEVRLQELEE 559


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 17/174 (9%)

Query: 31  SEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSD 90
           +EE E E++ SE E GG E  +D    E VS      P+  K   N  K + +K    +D
Sbjct: 16  AEEMENEDEMSEEEDGGLEAFDDFFPVEPVSLPKKKKPK--KLKENKCKGKRKKKEGSND 73

Query: 91  EDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDND 150
           E S+ + D+ + + +S+  +    K ++K + D+K     E +A    R+K++E +DDND
Sbjct: 74  ELSENEEDLEE-KSESEGSDYSPNKKKKKKLKDKK-----EKKA---KRKKKDEDEDDND 124

Query: 151 DESVKSSRNVN------NKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKK 198
           D  +K  ++          D  D + S+ED  +  + +  S  +  L+ KK  K
Sbjct: 125 DGCLKEPKSSGQLMAEWGLDDVDYLFSEEDYHTLTNYKAFSQFLRPLIAKKNPK 178


>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
          Length = 1726

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 52/184 (28%), Positives = 77/184 (41%), Gaps = 18/184 (9%)

Query: 23  QIVELGEESEEQECEEDGSETETGG------QEDLEDLQEEEEVSDMGGDNPEVGKKARN 76
           + VE  ++ EE+E E    + E G        +D ED  EE+E SD G    +VG K R 
Sbjct: 29  KFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRK 88

Query: 77  SSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYL 136
            + F+        D   D DFD+ +     KV+  G    R K + D++     E E   
Sbjct: 89  RTSFD--------DRLEDDDFDLIEENLGVKVKR-GQKYRRVKKMSDDE--DDDEEEYGK 137

Query: 137 ENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDE-DIASDHDDELGSNKMMKLLKKK 195
           E  EKE   ++   D   +  +         P E +E D  SD DD +  +    L K K
Sbjct: 138 EEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPK 197

Query: 196 QKKE 199
            +K+
Sbjct: 198 WRKK 201



 Score = 35.8 bits (81), Expect = 0.028
 Identities = 39/167 (23%), Positives = 67/167 (40%), Gaps = 24/167 (14%)

Query: 37  EEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLD 96
           +ED  E E G +E  ++   EE   D  G+  +   +A  +   E  +     DE+SD+D
Sbjct: 127 DEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEED----DEESDID 182

Query: 97  FDI--------SKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
             I         K + + K+        +E   I    F   E E Y E  E+ EE  + 
Sbjct: 183 DFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEY 242

Query: 149 NDDES-----VKSSRNVNNK-------DFFDPVESDEDIASDHDDEL 183
            DDE+     V+  +    +       + ++P E +    +D D+E+
Sbjct: 243 EDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEI 289


>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
           sapiens]
          Length = 1150

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 28/101 (27%), Positives = 54/101 (53%), Gaps = 9/101 (8%)

Query: 90  DEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDN 149
           ++D     D  K +++ +   T   KP+ +   D+K     + +   + R+KE++RKDD+
Sbjct: 801 EKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDK-----DKKEDRDERKKEDKRKDDS 855

Query: 150 DDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMK 190
            D+    +   NN+D +DP+E++E  A D +D+    +M K
Sbjct: 856 KDDD--ETEEDNNQDEYDPMEAEE--AEDEEDDRDEEEMTK 892


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 40/168 (23%), Positives = 73/168 (43%), Gaps = 10/168 (5%)

Query: 39  DGSETETGGQEDLEDLQEEEEVSDMG--GDNPEVGKKARNSSKFELRKSP----VFSDED 92
           DGSE +   +++ + ++E   ++  G  GD  +   ++R   K   +  P       +ED
Sbjct: 162 DGSEED---EDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNED 218

Query: 93  SDLDFDISKLEQQSKVQNTGHGKPREKSIID-EKFFQLSEMEAYLENREKEEERKDDNDD 151
            D  F I  + Q+   +     K R++      K  +  E+E   +++ K++E +   ++
Sbjct: 219 DDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEE 278

Query: 152 ESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           E+VKS   V+        E  E   +  DD  G  K     KKK +KE
Sbjct: 279 ETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKE 326



 Score = 37.7 bits (86), Expect = 0.007
 Identities = 28/133 (21%), Positives = 57/133 (42%), Gaps = 15/133 (11%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           EE+      E+  +TE  G +D E +  +EE   + G          N    E++++P  
Sbjct: 484 EETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEG----------NKVHIEVKENPEE 533

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKD- 147
            +E+ + + +  + E++ + +    G   ++   DEK     +    L+ +  +E   D 
Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGSEGDEE--DEKVSDEKDSGKTLDKKPSKEMSSDS 591

Query: 148 --DNDDESVKSSR 158
             D+DD+  K  R
Sbjct: 592 EYDSDDDRTKEER 604



 Score = 35.4 bits (80), Expect = 0.036
 Identities = 34/150 (22%), Positives = 62/150 (41%), Gaps = 20/150 (13%)

Query: 20  DPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSK 79
           D W+ +   EE+E+ E  +   E +   +E+ E+ +EEEE  +   +  E G+   +   
Sbjct: 504 DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGD 563

Query: 80  FELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENR 139
            E  K  V  ++DS    D    ++ S          R K           E  AY + +
Sbjct: 564 EEDEK--VSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTK-----------EERAYDKAK 610

Query: 140 EKEEERKDDNDDESVKSSRNVNNKDFFDPV 169
            + E+R+       ++ S+NVN +    P+
Sbjct: 611 RRIEKRR-------LEHSKNVNTEKLRAPI 633



 Score = 35.0 bits (79), Expect = 0.047
 Identities = 36/184 (19%), Positives = 75/184 (40%), Gaps = 23/184 (12%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           E +EE+   +D  +    G++   D  + EE+ D          K   S K    K  ++
Sbjct: 85  ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED----------KDSKSKKTAKPKVEMY 134

Query: 89  SDEDSDLDFDISKLEQQSKVQNT------------GHGKPREKSIIDEKFFQLSEMEAYL 136
           S  D D DF+    + + K Q +               K +E+S I+       E + +L
Sbjct: 135 SGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFL 194

Query: 137 ENREKEEERKDDNDDESVKSSRNVNNKDF-FDPVESDEDIASDHDDELGSNKMMKLLKKK 195
           ++R+ +++ + +    +++S    ++  F    V   +    + + +    +  KL K K
Sbjct: 195 QSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLK 254

Query: 196 QKKE 199
           +K+E
Sbjct: 255 EKEE 258



 Score = 32.0 bits (71), Expect = 0.40
 Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 7/67 (10%)

Query: 140 EKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           E+EEE +++ D+ES +        +  +  E DE ++ + D         K L KK  KE
Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSG-------KTLDKKPSKE 586

Query: 200 AFLKCEY 206
                EY
Sbjct: 587 MSSDSEY 593



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 25/127 (19%), Positives = 60/127 (47%), Gaps = 18/127 (14%)

Query: 38  EDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSDEDSDLDF 97
           E+ +ET T  ++D E  +++++     G+  E  K+ +        K+ V + +++    
Sbjct: 296 EEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS----KATVKAMQEA---- 347

Query: 98  DISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDNDDESVKSS 157
            ++KL+++ +         R+K   +E+  +L E+EA  +  E+ E+ K +   +  K  
Sbjct: 348 -LAKLKEEEE---------RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKER 397

Query: 158 RNVNNKD 164
           +    K+
Sbjct: 398 KERLKKE 404


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 8/129 (6%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           GEE EE+E EE+ + TE G Q         EE  D+   +   G   R+    E      
Sbjct: 192 GEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQG-HEEDDDDD 250

Query: 88  FSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKD 147
             D+D D D D+S   +    ++ GHG   ++ + D    +    +    +R  EE   D
Sbjct: 251 DDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHR----DPSHRHRSHEE---D 303

Query: 148 DNDDESVKS 156
           DNDD+ V +
Sbjct: 304 DNDDDDVST 312



 Score = 32.0 bits (71), Expect = 0.40
 Identities = 32/157 (20%), Positives = 57/157 (36%), Gaps = 14/157 (8%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           ELG ++          ET  G +  ++++        +  D   + K      K E  + 
Sbjct: 433 ELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEK-EKEED 491

Query: 86  PVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEER 145
           P   +ED +        EQ  K   T HG   ++   DE+     E      N+E+EEE 
Sbjct: 492 PGSHEEDDESS------EQGEK--GTHHGSRDQEDEEDEE-----EGHGLSLNQEEEEEE 538

Query: 146 KDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDE 182
             + ++E     R     +   P+  D     + ++E
Sbjct: 539 DKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEE 575



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 16/74 (21%), Positives = 36/74 (48%), Gaps = 3/74 (4%)

Query: 109 QNTGHGKPREKSIIDEKFFQ--LSEMEAYLENREKEEERKDDNDDESVKSS-RNVNNKDF 165
           ++ GHG   ++ + D           + + E+ + +++  DD+DD+ V    R+  ++  
Sbjct: 215 RHRGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQ 274

Query: 166 FDPVESDEDIASDH 179
              +E DED++  H
Sbjct: 275 GHGIEEDEDVSDGH 288


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 44.3 bits (103), Expect = 8e-05
 Identities = 39/135 (28%), Positives = 66/135 (48%), Gaps = 21/135 (15%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           GEE EE+E EE+  E E  G+E+ E+ +EEEE    GG+  E+G++          +  V
Sbjct: 405 GEEEEEEEEEEEEEEGE--GEEEEEEGEEEEE---EGGEGEELGEEEEVE-----EEGDV 454

Query: 88  FSDEDSDLDFDISK--LEQQSKVQNT--------GHGKPREKSIIDEKFFQLSEMEAYLE 137
            SDE+ + D + S   LE +   Q           +G   E       F +  E ++  +
Sbjct: 455 DSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGE-DSDSD 513

Query: 138 NREKEEERKDDNDDE 152
           + E+++E +DD D++
Sbjct: 514 SEEEDDEEEDDEDED 528


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 29/189 (15%)

Query: 26  ELGEESEEQECEEDGSE--TETGGQEDLEDLQEEEEVSDMGGD--------NPEVGKKAR 75
           E  E+  E+E +ED SE  +E G + + E+   E+++ + G +        + E+ +   
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDS 597

Query: 76  NSSKFELRKSP-VFSDEDSDLDFDISKLEQQS------KVQNTGHGKPREKSIIDEKFFQ 128
            +S+FE   S  V  +E S+ +FD    E++       KV +    +  ++   DEK  +
Sbjct: 598 ENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLE 657

Query: 129 LSEMEAYLENR-EKEEERKDDNDDESVKSSR-----------NVNNKDFFDPVESDEDIA 176
            ++ +A   +  EK  E  DD +DE                 + +N+  FD  E   +  
Sbjct: 658 AADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKL 717

Query: 177 SDHDDELGS 185
            D  DE G+
Sbjct: 718 FDDSDERGT 726



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 40/166 (24%), Positives = 75/166 (45%), Gaps = 19/166 (11%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQE-------EEEVSDMGGDNPEVGKKARNSS 78
           E  +++ + +CEE+G   E+    + E  +E       EE+ S+   D     K++ + S
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           + E  ++ +    + DLD + S+ E    V +    K  E++  +   F+    E  L+ 
Sbjct: 562 EREFEENGL----EKDLDEEGSEKELHENVLD----KELEENDSENSEFEDDGSEKVLDE 613

Query: 139 REKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELG 184
              E E  +D+D++  +   +   K F D  ESDE    ++ DE G
Sbjct: 614 EGSEREFDEDSDEK--EEEEDTYEKVFDD--ESDEKEDEEYADEKG 655



 Score = 31.2 bits (69), Expect = 0.68
 Identities = 36/177 (20%), Positives = 69/177 (38%), Gaps = 16/177 (9%)

Query: 30  ESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-------PEVGKKARNSSKFEL 82
           + ++ E  EDG E E G  E+       E+ ++ G          P+ G +   S K   
Sbjct: 427 DEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESE 486

Query: 83  RKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKE 142
             +PV   E+     +  K   ++  +  G  K  E  +  E     SE E        +
Sbjct: 487 EGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKE-----SEEEV----GPTK 537

Query: 143 EERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           E  +DD++ ES +      ++D  +    +  +  D D+E    ++ + +  K+ +E
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEE 594


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 45/189 (23%), Positives = 82/189 (43%), Gaps = 29/189 (15%)

Query: 26  ELGEESEEQECEEDGSE--TETGGQEDLEDLQEEEEVSDMGGD--------NPEVGKKAR 75
           E  E+  E+E +ED SE  +E G + + E+   E+++ + G +        + E+ +   
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDS 597

Query: 76  NSSKFELRKSP-VFSDEDSDLDFDISKLEQQS------KVQNTGHGKPREKSIIDEKFFQ 128
            +S+FE   S  V  +E S+ +FD    E++       KV +    +  ++   DEK  +
Sbjct: 598 ENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLE 657

Query: 129 LSEMEAYLENR-EKEEERKDDNDDESVKSSR-----------NVNNKDFFDPVESDEDIA 176
            ++ +A   +  EK  E  DD +DE                 + +N+  FD  E   +  
Sbjct: 658 AADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKL 717

Query: 177 SDHDDELGS 185
            D  DE G+
Sbjct: 718 FDDSDERGT 726



 Score = 37.0 bits (84), Expect = 0.012
 Identities = 40/166 (24%), Positives = 75/166 (45%), Gaps = 19/166 (11%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQE-------EEEVSDMGGDNPEVGKKARNSS 78
           E  +++ + +CEE+G   E+    + E  +E       EE+ S+   D     K++ + S
Sbjct: 502 ESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGS 561

Query: 79  KFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLEN 138
           + E  ++ +    + DLD + S+ E    V +    K  E++  +   F+    E  L+ 
Sbjct: 562 EREFEENGL----EKDLDEEGSEKELHENVLD----KELEENDSENSEFEDDGSEKVLDE 613

Query: 139 REKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELG 184
              E E  +D+D++  +   +   K F D  ESDE    ++ DE G
Sbjct: 614 EGSEREFDEDSDEK--EEEEDTYEKVFDD--ESDEKEDEEYADEKG 655



 Score = 31.2 bits (69), Expect = 0.68
 Identities = 36/177 (20%), Positives = 69/177 (38%), Gaps = 16/177 (9%)

Query: 30  ESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDN-------PEVGKKARNSSKFEL 82
           + ++ E  EDG E E G  E+       E+ ++ G          P+ G +   S K   
Sbjct: 427 DEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESE 486

Query: 83  RKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKE 142
             +PV   E+     +  K   ++  +  G  K  E  +  E     SE E        +
Sbjct: 487 EGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKE-----SEEEV----GPTK 537

Query: 143 EERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKE 199
           E  +DD++ ES +      ++D  +    +  +  D D+E    ++ + +  K+ +E
Sbjct: 538 ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEE 594


>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
          Length = 740

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 9/154 (5%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           E  EE EE+E EE+   T++  +EDLE +QE +E  D   D  E     ++  K  +   
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQE-DDEEEDEEEEAAAGKDGDKSPMSSL 500

Query: 86  PVFSDEDSDLDFDISKL--EQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEE 143
            + ++++ +    IS+   EQQ+K      G+    S++ E+    S ++A     + EE
Sbjct: 501 QISNEKNLEPGKQISRSSGEQQNK------GRIVSPSLLSEEPLAPSSIDAESNGEQPEE 554

Query: 144 ERKDDNDDESVKSSRNVNNKDFFDPVESDEDIAS 177
              ++    S      +       P   + DI+S
Sbjct: 555 LTLEEESPVSQLFELEIEALPLDTPSSVETDISS 588



 Score = 27.7 bits (60), Expect = 7.6
 Identities = 13/51 (25%), Positives = 28/51 (54%), Gaps = 2/51 (3%)

Query: 137 ENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNK 187
           E+ E+EEE +++ ++E+  S    + +   +  E DE+   D ++E  + K
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE--EDEEEEAAAGK 490



 Score = 27.3 bits (59), Expect = 9.9
 Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 26/161 (16%)

Query: 23  QIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFEL 82
           Q+ E  E+ EE++ EE+ +  + G +  +  LQ   E       N E GK+   SS  + 
Sbjct: 469 QMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNE------KNLEPGKQISRSSGEQQ 522

Query: 83  RKSPVFSDEDSDLDFDISKLEQQ----SKVQNTGHGKPREKSIIDEK--FFQLSEMEAYL 136
            K  + S          S L ++    S +    +G+  E+  ++E+    QL E+E  +
Sbjct: 523 NKGRIVSP---------SLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELE--I 571

Query: 137 ENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIAS 177
           E    +     + D   + SSR  + + F   +E+   + S
Sbjct: 572 EALPLDTPSSVETD---ISSSRKQSEEPFTTVLENGAGMVS 609


>gi|215422388 death-domain associated protein isoform a [Homo
           sapiens]
          Length = 740

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 9/154 (5%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           E  EE EE+E EE+   T++  +EDLE +QE +E  D   D  E     ++  K  +   
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQE-DDEEEDEEEEAAAGKDGDKSPMSSL 500

Query: 86  PVFSDEDSDLDFDISKL--EQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEE 143
            + ++++ +    IS+   EQQ+K      G+    S++ E+    S ++A     + EE
Sbjct: 501 QISNEKNLEPGKQISRSSGEQQNK------GRIVSPSLLSEEPLAPSSIDAESNGEQPEE 554

Query: 144 ERKDDNDDESVKSSRNVNNKDFFDPVESDEDIAS 177
              ++    S      +       P   + DI+S
Sbjct: 555 LTLEEESPVSQLFELEIEALPLDTPSSVETDISS 588



 Score = 27.7 bits (60), Expect = 7.6
 Identities = 13/51 (25%), Positives = 28/51 (54%), Gaps = 2/51 (3%)

Query: 137 ENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNK 187
           E+ E+EEE +++ ++E+  S    + +   +  E DE+   D ++E  + K
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE--EDEEEEAAAGK 490



 Score = 27.3 bits (59), Expect = 9.9
 Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 26/161 (16%)

Query: 23  QIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFEL 82
           Q+ E  E+ EE++ EE+ +  + G +  +  LQ   E       N E GK+   SS  + 
Sbjct: 469 QMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNE------KNLEPGKQISRSSGEQQ 522

Query: 83  RKSPVFSDEDSDLDFDISKLEQQ----SKVQNTGHGKPREKSIIDEK--FFQLSEMEAYL 136
            K  + S          S L ++    S +    +G+  E+  ++E+    QL E+E  +
Sbjct: 523 NKGRIVSP---------SLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELE--I 571

Query: 137 ENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIAS 177
           E    +     + D   + SSR  + + F   +E+   + S
Sbjct: 572 EALPLDTPSSVETD---ISSSRKQSEEPFTTVLENGAGMVS 609


>gi|215422366 death-domain associated protein isoform b [Homo
           sapiens]
          Length = 752

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/154 (24%), Positives = 68/154 (44%), Gaps = 9/154 (5%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           E  EE EE+E EE+   T++  +EDLE +QE +E  D   D  E     ++  K  +   
Sbjct: 454 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQE-DDEEEDEEEEAAAGKDGDKSPMSSL 512

Query: 86  PVFSDEDSDLDFDISKL--EQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEE 143
            + ++++ +    IS+   EQQ+K      G+    S++ E+    S ++A     + EE
Sbjct: 513 QISNEKNLEPGKQISRSSGEQQNK------GRIVSPSLLSEEPLAPSSIDAESNGEQPEE 566

Query: 144 ERKDDNDDESVKSSRNVNNKDFFDPVESDEDIAS 177
              ++    S      +       P   + DI+S
Sbjct: 567 LTLEEESPVSQLFELEIEALPLDTPSSVETDISS 600



 Score = 27.7 bits (60), Expect = 7.6
 Identities = 13/51 (25%), Positives = 28/51 (54%), Gaps = 2/51 (3%)

Query: 137 ENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNK 187
           E+ E+EEE +++ ++E+  S    + +   +  E DE+   D ++E  + K
Sbjct: 454 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEE--EDEEEEAAAGK 502



 Score = 27.3 bits (59), Expect = 9.9
 Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 26/161 (16%)

Query: 23  QIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFEL 82
           Q+ E  E+ EE++ EE+ +  + G +  +  LQ   E       N E GK+   SS  + 
Sbjct: 481 QMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNE------KNLEPGKQISRSSGEQQ 534

Query: 83  RKSPVFSDEDSDLDFDISKLEQQ----SKVQNTGHGKPREKSIIDEK--FFQLSEMEAYL 136
            K  + S          S L ++    S +    +G+  E+  ++E+    QL E+E  +
Sbjct: 535 NKGRIVSP---------SLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELE--I 583

Query: 137 ENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIAS 177
           E    +     + D   + SSR  + + F   +E+   + S
Sbjct: 584 EALPLDTPSSVETD---ISSSRKQSEEPFTTVLENGAGMVS 621


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
           sapiens]
          Length = 1710

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 40/162 (24%), Positives = 67/162 (41%), Gaps = 22/162 (13%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEE-------EEVSDMGGDNPEVGKKARNSSKFE 81
           ++ + Q     GSE ++   ED +D   E       +E   M G        + + S+ E
Sbjct: 110 QQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEE 169

Query: 82  LRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREK 141
             KS   S ++++ D++     +  K QN    K   K I+ +K  Q+   E      E 
Sbjct: 170 REKS---SCDETESDYEPKNKVKSRKPQNRSKSK-NGKKILGQKKRQIDSSE------ED 219

Query: 142 EEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDEL 183
           ++E   DND  S +    VN        + DE++ +D DD L
Sbjct: 220 DDEEDYDNDKRSSRRQATVNVS-----YKEDEEMKTDSDDLL 256


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 54/200 (27%), Positives = 82/200 (41%), Gaps = 41/200 (20%)

Query: 32  EEQECEEDGSETETGGQE--------DLED-LQEEEEVSDMGGDN----PEVGKKA---- 74
           ++Q+ +ED  E E  G+         DLED L+   + SD  G+     P+  KKA    
Sbjct: 183 KDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAK 242

Query: 75  --RNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSI----------I 122
             R   K +      F D D D DF+  +++  S   ++   +P  K+           +
Sbjct: 243 GGRKKKKKKGSDDEAFEDSD-DGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGV 301

Query: 123 DEKFFQLSEMEAYL---ENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDH 179
           DE+     E E      E++E+EEE+K     E  K  R  +++      ESD    SD 
Sbjct: 302 DEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQE--KKRRKDSSE------ESDSSEESDI 353

Query: 180 DDELGSNKMMKLLKKKQKKE 199
           D E  S   M   K   K+E
Sbjct: 354 DSEASSALFMAKKKTPPKRE 373



 Score = 27.7 bits (60), Expect = 7.6
 Identities = 21/85 (24%), Positives = 41/85 (48%), Gaps = 10/85 (11%)

Query: 136 LENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELG--------SNK 187
           ++ R  +++ +D++++E  K  R   ++     +E D +++SD  D  G        + K
Sbjct: 177 MQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKK 236

Query: 188 MMKLLK--KKQKKEAFLKCEYFETS 210
              L K  +K+KK+     E FE S
Sbjct: 237 KAPLAKGGRKKKKKKGSDDEAFEDS 261


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
           [Homo sapiens]
          Length = 666

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 44/152 (28%), Positives = 69/152 (45%), Gaps = 32/152 (21%)

Query: 31  SEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSD 90
           SE +  E+  S+ E  G+ED  D  ++E++      N +  ++A+ S + +L+ S    D
Sbjct: 130 SEAEGSEKAHSDDEKWGREDKSDQSDDEKIQ-----NSDDEERAQGSDEDKLQNS----D 180

Query: 91  EDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDND 150
           +D              K+QNT   +  + S  D++  QLSE E    N + E     DND
Sbjct: 181 DDE-------------KMQNTDDEERPQLS--DDERQQLSEEEK--ANSDDERPVASDND 223

Query: 151 DESVKSSRNVNNKDFFDPVESDEDIASDHDDE 182
           DE        N+ D   P  SDE+   + DDE
Sbjct: 224 DEKQ------NSDDEEQPQLSDEEKMQNSDDE 249



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 40/156 (25%), Positives = 63/156 (40%), Gaps = 16/156 (10%)

Query: 30  ESEEQECEEDGSETET---GGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSP 86
           E+ E+   ED   ++     G E   D ++E   SD G  + E    A  S K       
Sbjct: 89  EASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSE----AEGSEK------- 137

Query: 87  VFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERK 146
             SD++     D S      K+QN+   +  + S  DE   Q S+ +  ++N + EE  +
Sbjct: 138 AHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGS--DEDKLQNSDDDEKMQNTDDEERPQ 195

Query: 147 DDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDE 182
             +D+    S     N D   PV SD D    + D+
Sbjct: 196 LSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDD 231


>gi|61175239 transcription elongation factor A (SII)-like 5 [Homo
           sapiens]
          Length = 206

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 45/184 (24%), Positives = 70/184 (38%), Gaps = 35/184 (19%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G+   E+  E +G   + G  ED E   +EEE  DM G     GK+              
Sbjct: 10  GKPENERNLESEGKPEDEGSTED-EGKSDEEEKPDMEGKTECEGKR-------------- 54

Query: 88  FSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKD 147
              ED     D  +LE +   +  G  +  +K   + K       +A  E++ +  E++ 
Sbjct: 55  ---EDEGEPGDEGQLEDEGNQEKQGKSEGEDKPQSEGK----PASQAKPESQPRAAEKRP 107

Query: 148 DNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMK----------LLKKKQK 197
             D    K+ R  +      P +S ED+   H   L S +MM+           L+KKQK
Sbjct: 108 AEDYVPRKAKRKTDRGTDDSPKDSQEDLQERH---LSSEEMMRECGDVSRAQEELRKKQK 164

Query: 198 KEAF 201
              F
Sbjct: 165 MGGF 168


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 35/167 (20%), Positives = 66/167 (39%), Gaps = 41/167 (24%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           + S   EC++      + G ED+++ +EE+E  +   DN E G +     + +  +    
Sbjct: 83  DSSSVDECDD------SDGTEDMDE-KEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEI 135

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
            +ED D D D   +E                                 E  E+EEE +++
Sbjct: 136 EEEDEDDDEDGEDVED--------------------------------EEEEEEEEEEEE 163

Query: 149 NDDESVKSSRNVNNKDFFDPVESDEDIASDHD--DELGSNKMMKLLK 193
            ++E+     N +N       E D++   ++D  DEL +  ++ L K
Sbjct: 164 EEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGK 210



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 38/161 (23%), Positives = 72/161 (44%), Gaps = 6/161 (3%)

Query: 26  ELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKS 85
           E G+  EE+E EE+  + +  G ED+ED +EEEE  +   +  E      N     + + 
Sbjct: 125 EEGDREEEEEIEEEDEDDDEDG-EDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQD 183

Query: 86  PVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEER 145
               D ++D   +  +L  +S +     GK  E +    +    SEM +   N  +++  
Sbjct: 184 TEKDDNNNDEYDNYDELVAKSLL---NLGKIAEDAAYRAR--TESEMNSNTSNSLEDDSD 238

Query: 146 KDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSN 186
           K++N     + S ++++    + V+S + +A  H   L  N
Sbjct: 239 KNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSEN 279



 Score = 37.4 bits (85), Expect = 0.010
 Identities = 35/167 (20%), Positives = 68/167 (40%), Gaps = 13/167 (7%)

Query: 29  EESEEQECEEDGSETETGGQEDLED----LQEEEEVSDMGGDNPEVGKKARNSSKFELRK 84
           +E EE E EE   + +  G ED ED     +EEEE+ +   D+ E G+   +  + E  +
Sbjct: 100 DEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEE 159

Query: 85  SPVFSD---EDSDLDFDISKLEQQS-KVQNTGHGKPREKSIIDEKFFQLSEMEAYLENRE 140
                +   ED  ++   +++ Q + K  N          ++ +    L ++      R 
Sbjct: 160 EEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRA 219

Query: 141 KEEERKDDNDDESVK----SSRNVNNKDFFDPVESDEDIASDHDDEL 183
           + E   + N   S++     + N+  K     ++ D D+  +  D L
Sbjct: 220 RTESEMNSNTSNSLEDDSDKNENLGRKSELS-LDLDSDVVRETVDSL 265


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 42.0 bits (97), Expect = 4e-04
 Identities = 40/146 (27%), Positives = 68/146 (46%), Gaps = 11/146 (7%)

Query: 17   RVADPWQIVELGEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARN 76
            R A P ++   GEE E++   E+   TE    E+ E  +EEEE  D   D+ +  +   +
Sbjct: 1022 RPARPLELDSGGEEDEKESLSEEQESTE----EEEEAEEEEEEEDDDDDDSDDRDESEND 1077

Query: 77   SSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIID---EKFFQLSEME 133
                 L ++    + DSD +  +S +   SK + T   +  E S  +   E     SE E
Sbjct: 1078 DEDTALSEASEKDEGDSDEEETVSIV--TSKAEATSSSESSESSEFESSSESSPSSSEDE 1135

Query: 134  AYLENREKEEERKDDN--DDESVKSS 157
              +  RE+EEE +++    +ES+ S+
Sbjct: 1136 EEVVAREEEEEEEEEEMVAEESMASA 1161



 Score = 32.7 bits (73), Expect = 0.24
 Identities = 21/69 (30%), Positives = 33/69 (47%), Gaps = 4/69 (5%)

Query: 114  GKPREKSIIDEKFFQLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKDFFDPVESDE 173
            G+  EK  + E+     E     E  E+EEE +DD+DD+S     + N+ +     E+ E
Sbjct: 1033 GEEDEKESLSEE----QESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088

Query: 174  DIASDHDDE 182
                D D+E
Sbjct: 1089 KDEGDSDEE 1097


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 14/172 (8%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +E E QE E++  E E   + + E  + E E  +   +  +  ++ R   +   R     
Sbjct: 298 KEKERQEIEKERRERERERERERERRERERE-REREREREKEKERERERERDRDRDRTKE 356

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
            D D D + D  +  ++S  +N    + REKS   E+             RE+E ER+ +
Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRER------------ERERERERERE 404

Query: 149 NDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKEA 200
            + E  +       ++     E D+    + D+E  + +  KL +K ++KEA
Sbjct: 405 REREREREREREREREREREREKDKKRDREEDEE-DAYERRKLERKLREKEA 455



 Score = 33.1 bits (74), Expect = 0.18
 Identities = 39/199 (19%), Positives = 80/199 (40%), Gaps = 32/199 (16%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEE-----EEVSDMGGDNPEVGKKARNSSKFELR 83
           E+  E+E E D     T  ++   D + +     E  SD   D     +K+R+  +   R
Sbjct: 338 EKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERER 397

Query: 84  KSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQ-------LSEMEAYL 136
           +     + + + + +  +  ++ + +     K R++   +E  ++       L E EA  
Sbjct: 398 EREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAY 457

Query: 137 ENR---------------EKEEERKDDNDDESVKSSRNVNNKDFFDPVESDEDIASDHDD 181
           + R               EKE ER+++   E  K ++ +  K+F +  + D D   D   
Sbjct: 458 QERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRL--KEFLEDYDDDRD---DPKY 512

Query: 182 ELGSNKMMKLLKKKQKKEA 200
             GS    +L  ++++ EA
Sbjct: 513 YRGSALQKRLRDREKEMEA 531



 Score = 30.8 bits (68), Expect = 0.89
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%)

Query: 68  PEVGKKARNSSKFELRKSPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFF 127
           P + K+  N+ + E  K  + S E S       KLE++      G  +   + I  E+  
Sbjct: 257 PLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEK-----GKKEKERQEIEKERRE 311

Query: 128 QLSEMEAYLENREKEEERKDDNDDESVKSSRNVNNKD 164
           +  E E   E RE+E ER+ + + E  K       +D
Sbjct: 312 RERERERERERREREREREREREREKEKERERERERD 348



 Score = 28.5 bits (62), Expect = 4.4
 Identities = 29/153 (18%), Positives = 66/153 (43%), Gaps = 22/153 (14%)

Query: 27  LGEESEEQECEEDGSETETGG--QEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRK 84
           L E  E+ + + D  +   G   Q+ L D ++E E  +          + R   + E  +
Sbjct: 496 LKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERD--------RKREKEELEEIR 547

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + ++   D D ++ ++EQ+++       + R+  I  E      E E   E ++++EE
Sbjct: 548 QRLLAEGHPDPDAELQRMEQEAE-------RRRQPQIKQE-----PESEEEEEEKQEKEE 595

Query: 145 RKDDNDDESVKSSRNVNNKDFFDPVESDEDIAS 177
           ++++  +E  +  +    K    P+ S   ++S
Sbjct: 596 KREEPMEEEEEPEQKPCLKPTLRPISSAPSVSS 628


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G E EE+E EE+  E  T  + + E+ +EEEE  + G ++ E    A   S  E+ +  +
Sbjct: 277 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE----ASEQSAEEVSEEEM 332

Query: 88  FSDEDSDLD----------FDISKLEQQSKVQNTGHGKPREKSIID 123
             DE+ + +          FD    E +   +  G G P+  ++ +
Sbjct: 333 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 378



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 30/150 (20%), Positives = 59/150 (39%), Gaps = 4/150 (2%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNP----EVGKKARNSSKFELRK 84
           E  +E+E   + S      +ED  D  +    S      P    E+G   +   + ++ +
Sbjct: 188 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 247

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + SD     D +      +S    +G G   E+   +E+  + S  E   E  E+EEE
Sbjct: 248 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 307

Query: 145 RKDDNDDESVKSSRNVNNKDFFDPVESDED 174
            +++    S ++S     +   + +  DE+
Sbjct: 308 EEEETGSNSEEASEQSAEEVSEEEMSEDEE 337



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 18/85 (21%), Positives = 37/85 (43%), Gaps = 1/85 (1%)

Query: 30  ESEEQECEEDGSETETG-GQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +SE +    + S  E+G G E+ E+ +EEEE      +  E  ++     + E   +   
Sbjct: 259 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 318

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGH 113
           + E S  +    ++ +  + +N  H
Sbjct: 319 ASEQSAEEVSEEEMSEDEERENENH 343


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G E EE+E EE+  E  T  + + E+ +EEEE  + G ++ E    A   S  E+ +  +
Sbjct: 287 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE----ASEQSAEEVSEEEM 342

Query: 88  FSDEDSDLD----------FDISKLEQQSKVQNTGHGKPREKSIID 123
             DE+ + +          FD    E +   +  G G P+  ++ +
Sbjct: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 388



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 30/150 (20%), Positives = 59/150 (39%), Gaps = 4/150 (2%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNP----EVGKKARNSSKFELRK 84
           E  +E+E   + S      +ED  D  +    S      P    E+G   +   + ++ +
Sbjct: 198 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 257

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + SD     D +      +S    +G G   E+   +E+  + S  E   E  E+EEE
Sbjct: 258 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 317

Query: 145 RKDDNDDESVKSSRNVNNKDFFDPVESDED 174
            +++    S ++S     +   + +  DE+
Sbjct: 318 EEEETGSNSEEASEQSAEEVSEEEMSEDEE 347



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 18/85 (21%), Positives = 37/85 (43%), Gaps = 1/85 (1%)

Query: 30  ESEEQECEEDGSETETG-GQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +SE +    + S  E+G G E+ E+ +EEEE      +  E  ++     + E   +   
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGH 113
           + E S  +    ++ +  + +N  H
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENH 353


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 36/173 (20%), Positives = 71/173 (41%), Gaps = 24/173 (13%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEE-VSDMGGDNPEVGKKARNSSKFELRKSPV 87
           E + ++   +  ++T T  +   ED+ ++E+  +D GG+  E   K              
Sbjct: 231 ERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPK-------------- 276

Query: 88  FSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKD 147
            S+E SDL   + +++  +K  N          I+  K  Q    E   ++ +K E++ D
Sbjct: 277 -SEEFSDLPCPVEEIKNYTKEHNN--------LILLNKDVQQESSEQKNKSTDKGEKKPD 327

Query: 148 DNDDESVKSSRNVNNKDFFDPVESDEDIASDHDDELGSNKMMKLLKKKQKKEA 200
            N+    K  +    +  FD  +  ED     D++    K ++ LK   +K +
Sbjct: 328 SNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNS 380



 Score = 34.7 bits (78), Expect = 0.062
 Identities = 34/162 (20%), Positives = 66/162 (40%), Gaps = 13/162 (8%)

Query: 31   SEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVFSD 90
            S   E +++ S +ET G++  ++  +++ +     D P + K+ R   +    ++ +   
Sbjct: 2833 SRVMEEKDEYSSSETTGEKPEQN--DDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMK 2890

Query: 91   EDSDLDFDISKLEQQS-----KVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEER 145
            +DS  D  I  +EQ       KV  T     +E + + E+     + E  +    +   R
Sbjct: 2891 DDSKTDTGIVTVEQSPSSSKLKVMQTDESN-KETANLQERSISNDDGEEKIVTSVRRRGR 2949

Query: 146  KDD-----NDDESVKSSRNVNNKDFFDPVESDEDIASDHDDE 182
            K       +DD           K   DPVE  ++  SD ++E
Sbjct: 2950 KPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEE 2991


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G E EE+E EE+  E  T  + + E+ +EEEE  + G ++ E    A   S  E+ +  +
Sbjct: 278 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE----ASEQSAEEVSEEEM 333

Query: 88  FSDEDSDLD----------FDISKLEQQSKVQNTGHGKPREKSIID 123
             DE+ + +          FD    E +   +  G G P+  ++ +
Sbjct: 334 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 379



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 30/150 (20%), Positives = 59/150 (39%), Gaps = 4/150 (2%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNP----EVGKKARNSSKFELRK 84
           E  +E+E   + S      +ED  D  +    S      P    E+G   +   + ++ +
Sbjct: 189 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 248

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + SD     D +      +S    +G G   E+   +E+  + S  E   E  E+EEE
Sbjct: 249 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 308

Query: 145 RKDDNDDESVKSSRNVNNKDFFDPVESDED 174
            +++    S ++S     +   + +  DE+
Sbjct: 309 EEEETGSNSEEASEQSAEEVSEEEMSEDEE 338



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 29/148 (19%), Positives = 59/148 (39%), Gaps = 11/148 (7%)

Query: 30  ESEEQECEEDGSETETG-GQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +SE +    + S  E+G G E+ E+ +EEEE      +  E  ++     + E   +   
Sbjct: 260 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 319

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
           + E S  +    ++ +  + +N  H       ++ E  F         E+ E EEE  + 
Sbjct: 320 ASEQSAEEVSEEEMSEDEERENENH-----LLVVPESRFDRDSG----ESEEAEEEVGEG 370

Query: 149 NDDESVKSSRN-VNNKDFFDPVESDEDI 175
               S  +  + V +     P+E  +++
Sbjct: 371 TPQSSALTEGDYVPDSPALSPIELKQEL 398


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G E EE+E EE+  E  T  + + E+ +EEEE  + G ++ E    A   S  E+ +  +
Sbjct: 287 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE----ASEQSAEEVSEEEM 342

Query: 88  FSDEDSDLD----------FDISKLEQQSKVQNTGHGKPREKSIID 123
             DE+ + +          FD    E +   +  G G P+  ++ +
Sbjct: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 388



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 30/150 (20%), Positives = 59/150 (39%), Gaps = 4/150 (2%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNP----EVGKKARNSSKFELRK 84
           E  +E+E   + S      +ED  D  +    S      P    E+G   +   + ++ +
Sbjct: 198 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 257

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + SD     D +      +S    +G G   E+   +E+  + S  E   E  E+EEE
Sbjct: 258 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 317

Query: 145 RKDDNDDESVKSSRNVNNKDFFDPVESDED 174
            +++    S ++S     +   + +  DE+
Sbjct: 318 EEEETGSNSEEASEQSAEEVSEEEMSEDEE 347



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 29/148 (19%), Positives = 59/148 (39%), Gaps = 11/148 (7%)

Query: 30  ESEEQECEEDGSETETG-GQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +SE +    + S  E+G G E+ E+ +EEEE      +  E  ++     + E   +   
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 328

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
           + E S  +    ++ +  + +N  H       ++ E  F         E+ E EEE  + 
Sbjct: 329 ASEQSAEEVSEEEMSEDEERENENH-----LLVVPESRFDRDSG----ESEEAEEEVGEG 379

Query: 149 NDDESVKSSRN-VNNKDFFDPVESDEDI 175
               S  +  + V +     P+E  +++
Sbjct: 380 TPQSSALTEGDYVPDSPALSPIELKQEL 407


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 27/106 (25%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 28  GEESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPV 87
           G E EE+E EE+  E  T  + + E+ +EEEE  + G ++ E    A   S  E+ +  +
Sbjct: 255 GSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE----ASEQSAEEVSEEEM 310

Query: 88  FSDEDSDLD----------FDISKLEQQSKVQNTGHGKPREKSIID 123
             DE+ + +          FD    E +   +  G G P+  ++ +
Sbjct: 311 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTE 356



 Score = 31.6 bits (70), Expect = 0.52
 Identities = 30/150 (20%), Positives = 59/150 (39%), Gaps = 4/150 (2%)

Query: 29  EESEEQECEEDGSETETGGQEDLEDLQEEEEVSDMGGDNP----EVGKKARNSSKFELRK 84
           E  +E+E   + S      +ED  D  +    S      P    E+G   +   + ++ +
Sbjct: 166 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE 225

Query: 85  SPVFSDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEE 144
             + SD     D +      +S    +G G   E+   +E+  + S  E   E  E+EEE
Sbjct: 226 RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEE 285

Query: 145 RKDDNDDESVKSSRNVNNKDFFDPVESDED 174
            +++    S ++S     +   + +  DE+
Sbjct: 286 EEEETGSNSEEASEQSAEEVSEEEMSEDEE 315



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 29/148 (19%), Positives = 59/148 (39%), Gaps = 11/148 (7%)

Query: 30  ESEEQECEEDGSETETG-GQEDLEDLQEEEEVSDMGGDNPEVGKKARNSSKFELRKSPVF 88
           +SE +    + S  E+G G E+ E+ +EEEE      +  E  ++     + E   +   
Sbjct: 237 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 296

Query: 89  SDEDSDLDFDISKLEQQSKVQNTGHGKPREKSIIDEKFFQLSEMEAYLENREKEEERKDD 148
           + E S  +    ++ +  + +N  H       ++ E  F         E+ E EEE  + 
Sbjct: 297 ASEQSAEEVSEEEMSEDEERENENH-----LLVVPESRFDRDSG----ESEEAEEEVGEG 347

Query: 149 NDDESVKSSRN-VNNKDFFDPVESDEDI 175
               S  +  + V +     P+E  +++
Sbjct: 348 TPQSSALTEGDYVPDSPALSPIELKQEL 375


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.128    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,836,096
Number of Sequences: 37866
Number of extensions: 450807
Number of successful extensions: 6600
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 245
Number of HSP's successfully gapped in prelim test: 428
Number of HSP's that attempted gapping in prelim test: 3006
Number of HSP's gapped (non-prelim): 2476
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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