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Search of human proteins with 169204908
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169204908 PREDICTED: similar to Thyroid hormone receptor
interactor 11 [Homo sapiens]
(352 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169204908 PREDICTED: similar to Thyroid hormone receptor inte... 690 0.0
gi|169205597 PREDICTED: similar to Thyroid hormone receptor inte... 690 0.0
gi|169203883 PREDICTED: hypothetical protein [Homo sapiens] 690 0.0
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 614 e-176
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ... 52 8e-07
gi|221139761 zinc finger protein 853 [Homo sapiens] 49 9e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 47 2e-05
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 47 3e-05
gi|71061468 centromere protein E [Homo sapiens] 47 3e-05
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 47 3e-05
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 47 3e-05
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 47 3e-05
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 47 3e-05
gi|42794779 myosin 18A isoform b [Homo sapiens] 47 3e-05
gi|28416946 myosin 18A isoform a [Homo sapiens] 47 3e-05
gi|38044112 restin isoform b [Homo sapiens] 46 4e-05
gi|4506751 restin isoform a [Homo sapiens] 46 4e-05
gi|4504063 golgin 97 [Homo sapiens] 46 4e-05
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens] 46 6e-05
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 45 1e-04
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 45 1e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 45 1e-04
gi|55770834 centromere protein F [Homo sapiens] 45 1e-04
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 44 2e-04
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 44 2e-04
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 44 2e-04
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 44 2e-04
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 44 2e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 44 2e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 3e-04
>gi|169204908 PREDICTED: similar to Thyroid hormone receptor
interactor 11 [Homo sapiens]
Length = 352
Score = 690 bits (1781), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE
Sbjct: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI
Sbjct: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG
Sbjct: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
Query: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240
SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF
Sbjct: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240
Query: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300
LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS
Sbjct: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300
Query: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ
Sbjct: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
>gi|169205597 PREDICTED: similar to Thyroid hormone receptor
interactor 11 [Homo sapiens]
Length = 352
Score = 690 bits (1781), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE
Sbjct: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI
Sbjct: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG
Sbjct: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
Query: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240
SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF
Sbjct: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240
Query: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300
LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS
Sbjct: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300
Query: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ
Sbjct: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
>gi|169203883 PREDICTED: hypothetical protein [Homo sapiens]
Length = 352
Score = 690 bits (1781), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE
Sbjct: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI
Sbjct: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG
Sbjct: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
Query: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240
SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF
Sbjct: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240
Query: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300
LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS
Sbjct: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300
Query: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ
Sbjct: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 614 bits (1584), Expect = e-176
Identities = 315/353 (89%), Positives = 332/353 (94%), Gaps = 1/353 (0%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETAL-LSASQQQVKQYALSLANLQMVLQHFQKE 59
MENASHQASVQVESLQEQLNVVSKQRDETAL LS SQ+QVKQYALSLANLQMVL+HFQ+E
Sbjct: 1627 MENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQE 1686
Query: 60 EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
EK+MYSAEL+KQKQLIAEWKK AE+LE KVISLQE LDEA+AALDSASRLTEQLD+KEEQ
Sbjct: 1687 EKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQ 1746
Query: 120 IEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLM 179
IEELK+QNE +QEMLDDVQKKL++LANS EGKVDKVLMRNLFI HFH PKNQRHEVLRLM
Sbjct: 1747 IEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLM 1806
Query: 180 GSILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVK 239
GSILGVRREEMEQLFHD+QG VTRWMTGWLG GSKSVPNTPLRPNQQSV+NSSFSE FVK
Sbjct: 1807 GSILGVRREEMEQLFHDDQGGVTRWMTGWLGGGSKSVPNTPLRPNQQSVVNSSFSELFVK 1866
Query: 240 FLETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPR 299
FLETESH S+PPPKLSVHDMKPL+SPGRRK DTNAPESFKDTAESRSGRR +VN LAPR
Sbjct: 1867 FLETESHPSIPPPKLSVHDMKPLDSPGRRKRDTNAPESFKDTAESRSGRRTDVNPFLAPR 1926
Query: 300 SAAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
SAAVPLINPAGLGPGGP HLLLKPISDV PTFTPLP LPDNSAGVVLKDL KQ
Sbjct: 1927 SAAVPLINPAGLGPGGPGHLLLKPISDVLPTFTPLPALPDNSAGVVLKDLLKQ 1979
Score = 53.1 bits (126), Expect = 4e-07
Identities = 50/202 (24%), Positives = 92/202 (45%), Gaps = 7/202 (3%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANL-QMVLQHFQKEE 60
E ++ +++ S LN + Q + L+ +Q++ + A N+ QM H KE
Sbjct: 735 EANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDH--KET 792
Query: 61 KSMYSAELQKQKQLIAEWKKKA---ESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
K + S+ L++QKQL KK E L+ + LQE LD+ AL L + ++ K+
Sbjct: 793 KDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKD 852
Query: 118 EQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGK-VDKVLMRNLFISHFHMPKNQRHEVL 176
+ +K++N QE L+ ++++ A + K +D V +S + K E +
Sbjct: 853 RSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEI 912
Query: 177 RLMGSILGVRREEMEQLFHDNQ 198
+ I+ + + QL Q
Sbjct: 913 KHHQKIIEDQNQSKMQLLQSLQ 934
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 16/152 (10%)
Query: 12 VESLQEQLNVVSKQRDETALLSASQQQVKQYAL-------------SLANLQMVLQHFQK 58
V+S+QE+ V ++RD+ +L+ Q+Q++ AL S L+ + H +
Sbjct: 1532 VKSMQEKTVVFQQERDQ-VMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLE 1590
Query: 59 EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEAD-AALDSASRLTEQLDLKE 117
E S Y+ E + A+ +KK LE K++S ++ A A L EQL++
Sbjct: 1591 SEDS-YTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVS 1649
Query: 118 EQIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
+Q +E Q QE + L NL LE
Sbjct: 1650 KQRDETALQLSVSQEQVKQYALSLANLQMVLE 1681
Score = 34.3 bits (77), Expect = 0.17
Identities = 30/166 (18%), Positives = 76/166 (45%), Gaps = 21/166 (12%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
+++ H + +E+ +++LN +++ L++ ++ +Q + ++ ++ K++
Sbjct: 465 LDSELHDLRLNLEAKEQELNQSISEKE--TLIAEIEELDRQNQEATKHMILIKDQLSKQQ 522
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLD-------EADAAL---------- 103
S + K KQ + + KK+ LE + + + LD +++ AL
Sbjct: 523 NEGDSI-ISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKL 581
Query: 104 -DSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSL 148
D L +QL+ +E ++K+N +E + +++L + N L
Sbjct: 582 EDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNEL 627
Score = 30.8 bits (68), Expect = 1.9
Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 27/135 (20%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQH----- 55
+++ H+ SV + Q++L +S++ E ++ Y + L+ +LQ
Sbjct: 229 IDDHQHEMSVLQNAHQQKLTEISRRHRE---------ELSDYEERIEELENLLQQGGSGV 279
Query: 56 FQKEEKSMYSAELQKQKQLI----AEWKKKAESLERKVISLQERLDEADAALDSASRLTE 111
+ + +Y E+QK Q++ E KK E LE K+ + ++L A+ D R
Sbjct: 280 IETDLSKIY--EMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRR--- 334
Query: 112 QLDLKEEQIEELKKQ 126
++EQ+ K+Q
Sbjct: 335 ----EQEQLNVEKRQ 345
>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
[Homo sapiens]
Length = 1235
Score = 52.0 bits (123), Expect = 8e-07
Identities = 41/153 (26%), Positives = 77/153 (50%), Gaps = 4/153 (2%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANL--QMVLQHFQ- 57
+E+ + SV+ ESL N+V ++ E +L+ QQ ++ S+ L Q Q+ +
Sbjct: 242 LEHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKA 301
Query: 58 KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDS-ASRLTEQLDLK 116
KE S + +L K+ I + +K+ E + +L+ L + DAA S ++ E++ K
Sbjct: 302 KENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHK 361
Query: 117 EEQIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
+ IE Q + +E+ + V+KK+ + LE
Sbjct: 362 KRDIELEASQLDRYKELKEQVRKKVATMTQQLE 394
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/184 (24%), Positives = 81/184 (44%), Gaps = 23/184 (12%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQK-- 58
EN SH ++L+V K +D S + +K LA+L + F+K
Sbjct: 303 ENTSHHL--------KKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQI 354
Query: 59 EEKSMY--------SAELQKQKQLIAEWKKKAESLERKVISLQ--ERLDEADAALDSASR 108
EE+ ++ +++L + K+L + +KK ++ +++ LQ ++ DE A +
Sbjct: 355 EEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRH 414
Query: 109 LTEQLDLKE--EQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFH 166
Q +LK+ EQIE+ KK+ E +E L E VD++ +S F+
Sbjct: 415 GEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEFN 474
Query: 167 MPKN 170
N
Sbjct: 475 EELN 478
Score = 31.6 bits (70), Expect = 1.1
Identities = 31/162 (19%), Positives = 73/162 (45%), Gaps = 24/162 (14%)
Query: 58 KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
+++K+ + +L+ + + + K +L+ + E +D A ++ + +L K+
Sbjct: 811 EKQKTRLNVQLEYSRSHLKKKLNKINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQ 870
Query: 118 EQIEEL---------KKQNEFQQEM---------LDDVQKKLVNLANSLEGKVDKVLMRN 159
+Q++++ K Q + ++E + +QK++V++ SLE K ++ N
Sbjct: 871 QQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLEQK--RLEKHN 928
Query: 160 LFISHFHMPKNQRHEVLRLMGSILGVRREEMEQLFHDNQGSV 201
L + K Q E++ L GS+ + EM Q ++
Sbjct: 929 LLLD----CKVQDIEIILLSGSLDDIIEVEMGTEAESTQATI 966
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 48.5 bits (114), Expect = 9e-06
Identities = 45/151 (29%), Positives = 79/151 (52%), Gaps = 15/151 (9%)
Query: 11 QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQK 70
QV QEQL +Q E LL Q+Q++Q L Q+ Q FQ++++ +LQ+
Sbjct: 186 QVLQQQEQLQ---QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQE-----QLQQ 237
Query: 71 QKQLI---AEWKKKAESLERKVISLQER-LDEADAALDSASRLTEQLDLKEEQIEELKKQ 126
Q+QL+ + + + + L+++ LQ++ L++ A L L +Q L+++Q ++L +Q
Sbjct: 238 QQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQ 297
Query: 127 NEFQQEMLDDVQKKLVNLANSLEGKVDKVLM 157
QQE L Q + L E +V+ LM
Sbjct: 298 ---QQEQLQQQQLQPPPLEPEEEEEVELELM 325
Score = 40.0 bits (92), Expect = 0.003
Identities = 49/219 (22%), Positives = 97/219 (44%), Gaps = 20/219 (9%)
Query: 7 QASVQVESLQEQLNVVSKQRD---ETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSM 63
Q Q E LQ+Q ++ Q+ + LL Q Q++Q L Q+ Q ++++ +
Sbjct: 227 QFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQL 286
Query: 64 YSAELQKQKQLIAEWKKKAESLERKVISLQ-ERLDEADAALDSASRLTEQLDLKEEQIEE 122
+ Q+Q+QL+ + +++ + + + L+ E +E + L +EQ E+Q +E
Sbjct: 287 ---QQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQ--ELEQQRQE 341
Query: 123 LKKQNEFQ-QEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGS 181
L++Q E + Q+ +Q KL LE ++++ Q+ L L
Sbjct: 342 LERQQELERQQEQRQLQLKLQEELQQLEQQLEQQ----------QQQLEQQEVQLELTPV 391
Query: 182 ILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTP 220
LG +++E++ Q + + G G +VP P
Sbjct: 392 ELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVPGAP 430
Score = 35.0 bits (79), Expect = 0.10
Identities = 27/140 (19%), Positives = 69/140 (49%), Gaps = 7/140 (5%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE- 60
E Q +Q++ L++Q +Q+ + L Q ++ + Q L Q+E+
Sbjct: 81 ETRPGQRELQLQQLEQQPE--PQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKH 138
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
+S++ EL+ + QL+ + + L+ + + Q+RL + L + +Q+ ++EQ+
Sbjct: 139 QSVHHQELKPELQLMHQ----QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQL 194
Query: 121 EELKKQNEFQQEMLDDVQKK 140
++ ++ + Q+ + +Q++
Sbjct: 195 QQQVQEQQLLQQQQEQLQQQ 214
Score = 34.3 bits (77), Expect = 0.17
Identities = 29/135 (21%), Positives = 67/135 (49%), Gaps = 16/135 (11%)
Query: 7 QASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA 66
Q +Q + +QEQ + +Q+++ A +QQV Q L Q Q++++ +
Sbjct: 156 QQQLQPQQVQEQQRL-QQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ 214
Query: 67 ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQ 126
+L +Q++ + + + + + QE+L + L L +Q L+++ +++ +Q
Sbjct: 215 QLLQQQEQLQQQQFQQQ---------QEQLQQQQQLL----LLQQQGQLQQQLLQQ--QQ 259
Query: 127 NEFQQEMLDDVQKKL 141
+ QQ++L+ Q +L
Sbjct: 260 AQLQQQLLEQQQAQL 274
Score = 33.1 bits (74), Expect = 0.38
Identities = 30/127 (23%), Positives = 65/127 (51%), Gaps = 10/127 (7%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
Q+QL+ + +++ + S Q++K L L + Q LQ Q +E+ LQ+Q++ +
Sbjct: 127 QQQLSQLQQEKHQ----SVHHQELKP-ELQLMHQQQQLQPQQVQEQQ----RLQQQQEQL 177
Query: 76 AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
+ + + + ++ LQ+++ E +L +Q L ++Q + ++Q + QQE L
Sbjct: 178 QTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ-QLLQQQEQLQQQQFQQQQEQLQ 236
Query: 136 DVQKKLV 142
Q+ L+
Sbjct: 237 QQQQLLL 243
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 47.4 bits (111), Expect = 2e-05
Identities = 49/204 (24%), Positives = 90/204 (44%), Gaps = 32/204 (15%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQ------VKQYALSLANLQMVLQ 54
+E + +VE L L +R TA + ++Q + ++ L Q L+
Sbjct: 1418 LEKTKQRLQGEVEDLMRDL-----ERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELE 1472
Query: 55 HFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLD 114
QKE +S+ S EL K + E + E+L R+ +LQE + + LTEQ+
Sbjct: 1473 AAQKESRSL-STELFKMRNAYEEVVDQLETLRRENKNLQEEISD----------LTEQIA 1521
Query: 115 LKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHE 174
+ ++E +K + ++ D+Q L + SLE + K+L L +S +++
Sbjct: 1522 ETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRK-- 1579
Query: 175 VLRLMGSILGVRREEMEQLFHDNQ 198
+ + EE+EQL ++Q
Sbjct: 1580 --------VIEKDEEIEQLKRNSQ 1595
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/165 (22%), Positives = 71/165 (43%), Gaps = 17/165 (10%)
Query: 1 MENASHQASVQVE----------SLQEQLNVVSKQRDETALLSASQQ--QVKQYALSLAN 48
+E AS S Q+E ++ L + Q + TA +Q V + + N
Sbjct: 1154 LEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDN 1213
Query: 49 LQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASR 108
LQ V Q +KE KS E+ I K ++ER +++++ E A + ++
Sbjct: 1214 LQRVKQKLEKE-KSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQ 1272
Query: 109 LTEQLDLKEEQIE----ELKKQNEFQQEMLDDVQKKLVNLANSLE 149
L L++++ +++ EL + E ++ ++ + K L LE
Sbjct: 1273 LIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLE 1317
Score = 39.7 bits (91), Expect = 0.004
Identities = 36/167 (21%), Positives = 75/167 (44%), Gaps = 14/167 (8%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
+E+ ++ L+ L V K++ A++ +VK + + L+ + KE+
Sbjct: 947 LEDKCSSLKRDIDDLELTLTKVEKEKH------ATENKVKNLSEEMTALEENISKLTKEK 1000
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
KS+ A Q L E + K L + L+++ D+ + +L+ +L L+ + ++
Sbjct: 1001 KSLQEAHQQTLDDLQVE-EDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKL 1059
Query: 121 E-ELKKQNEFQQEMLDDVQ------KKLVNLANSLEGKVDKVLMRNL 160
E +LK E ++ +D Q KK + L+ K+D + +L
Sbjct: 1060 EGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSL 1106
Score = 37.4 bits (85), Expect = 0.020
Identities = 27/119 (22%), Positives = 62/119 (52%), Gaps = 5/119 (4%)
Query: 11 QVESLQEQLNVVSKQRDETAL-LSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ 69
Q+++LQ + K++ E + + ++ + S +N++ + + ++ S A+ +
Sbjct: 1210 QIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVE-DQFSEIKAKDE 1268
Query: 70 KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNE 128
+Q QLI + + L+ + L R++E ++ + S+LT+ +Q+EELK+Q E
Sbjct: 1269 QQTQLIHDLNMQKARLQTQNGELSHRVEEKESLI---SQLTKSKQALTQQLEELKRQME 1324
Score = 37.4 bits (85), Expect = 0.020
Identities = 26/113 (23%), Positives = 57/113 (50%), Gaps = 11/113 (9%)
Query: 29 TALLSASQQQVKQYALSLANLQMVLQHFQKEEK---------SMYSAELQKQKQLIAEWK 79
T+L++ ++ A A ++ +Q + E+ +M + EL+K++ A +
Sbjct: 1725 TSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784
Query: 80 KKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
+ ++LE+ V LQ RLDEA+ + +Q+ E ++ EL+ + + +Q+
Sbjct: 1785 RMKKNLEQTVKDLQHRLDEAEQLALKGGK--KQIQKLENRVRELENELDVEQK 1835
Score = 36.2 bits (82), Expect = 0.045
Identities = 37/158 (23%), Positives = 65/158 (41%), Gaps = 20/158 (12%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
E+ Q + ++L +QL + +Q +E + +AL + L Q EE+
Sbjct: 1299 ESLISQLTKSKQALTQQLEELKRQMEE----ETKAKNAMAHALQSSRHDCDLLREQYEEE 1354
Query: 62 SMYSAELQ----KQKQLIAEWKKK--------AESLERKVISLQERLDEADAALDSASRL 109
AELQ K +A+W+ K E LE L +RL EA+ ++A+
Sbjct: 1355 QEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSK 1414
Query: 110 TEQLDLKEE----QIEELKKQNEFQQEMLDDVQKKLVN 143
L+ ++ ++E+L + E + KK N
Sbjct: 1415 CASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRN 1452
Score = 35.0 bits (79), Expect = 0.10
Identities = 36/171 (21%), Positives = 72/171 (42%), Gaps = 33/171 (19%)
Query: 7 QASVQVESLQEQLNV-------VSKQRDETA--LLSASQQQVKQYALSLANLQMVLQH-- 55
+ ++E L+E++ + KQR + A L S++ + + A ++M +
Sbjct: 1114 ELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREA 1173
Query: 56 -FQKEEKSMYSAELQ----------KQKQLIAEWKKKAESLERKVISLQERLDEADAALD 104
FQK + + A LQ KQ +AE ++ ++L+R L++ E +D
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1233
Query: 105 -----------SASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNL 144
S S + E+Q E+K ++E Q +++ D+ + L
Sbjct: 1234 DMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARL 1284
Score = 34.7 bits (78), Expect = 0.13
Identities = 32/145 (22%), Positives = 67/145 (46%), Gaps = 15/145 (10%)
Query: 36 QQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQER 95
Q+++ +A LQ +K +K + E + + E + E E K++ +Q
Sbjct: 1510 QEEISDLTEQIAETGKNLQEAEKTKK-LVEQEKSDLQVALEEVEGSLEHEESKILRVQLE 1568
Query: 96 LDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDV-------QKKLVNLANSL 148
L + + LD ++ K+E+IE+LK+ ++ E L V + + L +
Sbjct: 1569 LSQVKSELD------RKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKM 1622
Query: 149 EGKVDKVLMRNLFISHFHMPKNQRH 173
EG ++++ ++ L S+ M + Q+H
Sbjct: 1623 EGDLNEMEIQ-LGHSNRQMAETQKH 1646
Score = 29.3 bits (64), Expect = 5.6
Identities = 29/137 (21%), Positives = 60/137 (43%), Gaps = 12/137 (8%)
Query: 13 ESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQK 72
E L+EQL +V ++ LL +++K AL L + + S L Q
Sbjct: 1669 EDLKEQLAIVERRN---GLLLEELEEMK-VALEQTERTRRLSEQELLDASDRVQLLHSQN 1724
Query: 73 QLIAEWKKKAES--------LERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELK 124
+ KKK E+ +E + + ++A A+ A+ + E+L +++ L+
Sbjct: 1725 TSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784
Query: 125 KQNEFQQEMLDDVQKKL 141
+ + ++ + D+Q +L
Sbjct: 1785 RMKKNLEQTVKDLQHRL 1801
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 47.0 bits (110), Expect = 3e-05
Identities = 43/196 (21%), Positives = 87/196 (44%), Gaps = 41/196 (20%)
Query: 12 VESLQEQLNVVSKQRD-----------------ETALLSASQQQVKQYALSLANLQMVLQ 54
VE L+ QL + KQ+ E ++SA+ Q+ N+Q ++
Sbjct: 1727 VERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHL-----NVQQIVD 1781
Query: 55 HFQKEEKSMY---SAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTE 111
+E K+ + L K K+ + K + SL + L L + A + R E
Sbjct: 1782 RHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKE 1841
Query: 112 QLDLKEEQIEELKKQ----------NEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLF 161
++D + ++++ K+ + +Q +++++Q+K+ L N LEGKV++V ++ +
Sbjct: 1842 EIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPM- 1900
Query: 162 ISHFHMPKNQRHEVLR 177
KN + E++R
Sbjct: 1901 -----KEKNAKEELIR 1911
Score = 32.0 bits (71), Expect = 0.86
Identities = 30/168 (17%), Positives = 81/168 (48%), Gaps = 20/168 (11%)
Query: 8 ASVQVESL--QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYS 65
+ V+V L ++Q NV+ R +L+ Q+V+ L+L ++ + K E + +
Sbjct: 33 SKVEVNELKSEKQENVIHLFRITQSLMKMKAQEVE---LALEEVEKAGEEQAKFENQLKT 89
Query: 66 AELQKQKQLIAEWK----KKAESLERKVISLQERLDEADAALDSASR-------LTEQLD 114
++ + +L + + L ++ L+++L++ D L+ + + EQL
Sbjct: 90 KVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLA 149
Query: 115 LKEEQIE----ELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMR 158
L+ E+ E +L+++N+ ++ + + + +++ ++ + + +L R
Sbjct: 150 LRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSR 197
Score = 31.6 bits (70), Expect = 1.1
Identities = 50/254 (19%), Positives = 103/254 (40%), Gaps = 37/254 (14%)
Query: 2 ENASHQASVQVESLQEQLN--VVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE 59
E A + A ++ + + L + S +R + L +QQ+ +++ ++ LQ
Sbjct: 1246 EQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQE--KFSKTMIQLQ--------N 1295
Query: 60 EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
+K E++ +Q + K +E K+ L+E + + + + ++E +
Sbjct: 1296 DKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELR 1355
Query: 120 IEELKKQNEFQQE-----MLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHE 174
++ELK E ++ L+++ + +SLE ++++ +N F M +QR
Sbjct: 1356 LQELKLNRELVKDKEEIKYLNNIISEYERTISSLE---EEIVQQNKFHEERQMAWDQREV 1412
Query: 175 VLRLMGSILGVRREEM---EQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNS 231
L I ++ E+ Q F + GS+ P+ PL PNQ +
Sbjct: 1413 DLERQLDIFDRQQNEILNAAQKFEEATGSIPD-------------PSLPL-PNQLEIALR 1458
Query: 232 SFSECFVKFLETES 245
E LET +
Sbjct: 1459 KIKENIRIILETRA 1472
Score = 30.4 bits (67), Expect = 2.5
Identities = 35/157 (22%), Positives = 71/157 (45%), Gaps = 20/157 (12%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQ----YALSLANLQMVLQHFQKEEKSMYSAELQKQ 71
+E N SK R E L +Q+ Q Y + + + L ++ E S Y ++L K+
Sbjct: 153 EEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLS-RRGEDSDYRSQLSKK 211
Query: 72 K----------QLIAEWKKKAESLERKVI-SLQERLDEADAALDSASRLTEQLDLKEEQI 120
Q + E +K E +++ +L+E + E + D +R+ + + I
Sbjct: 212 NYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVI 271
Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLM 157
++LKK+N+ Q + ++L +L S + D +++
Sbjct: 272 DQLKKENDHYQLQV----QELTDLLKSKNEEDDPIMV 304
Score = 30.4 bits (67), Expect = 2.5
Identities = 48/196 (24%), Positives = 86/196 (43%), Gaps = 22/196 (11%)
Query: 12 VESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQM-----VLQHFQKEEKSMYSA 66
+ SL+E++ +K +E + ++ + L + + Q Q F++ S+
Sbjct: 1386 ISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDP 1445
Query: 67 ELQKQKQLIAEWKKKAES----LERKVI--SLQERLDEADAALDSASRLTEQLDLKEEQ- 119
L QL +K E+ LE + SL+E+L E ++AL RL EQ L ++
Sbjct: 1446 SLPLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESAL----RLAEQNILSRDKV 1501
Query: 120 IEELKKQNEFQQEMLDDVQKKLVNLANS-LEGKVDKVL-MRNLFISHFHMPKNQRHEVLR 177
I EL+ + E +K + L +E K L + + I++ NQ+ EVL+
Sbjct: 1502 INELRLRLPATAER----EKLIAELGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLK 1557
Query: 178 LMGSILGVRREEMEQL 193
+L REE ++
Sbjct: 1558 KYQRLLEKAREEQREI 1573
Score = 28.5 bits (62), Expect = 9.5
Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 23/151 (15%)
Query: 7 QASVQVESLQEQLNVVSKQRDETALLSAS---QQQVKQYALSLANLQMVLQHFQKEEKSM 63
+ S+ + SL+ +N + + E + AS + QV Q L+ L+ +KE +
Sbjct: 671 ETSLIIPSLERLVNAIESKNAE-GIFDASLHLKAQVDQLTGRNEELRQELRESRKEAIN- 728
Query: 64 YSAELQKQKQLIAEWKKKAESLERKVIS--LQERLDEADAALDSASRLTEQLDLKEEQIE 121
YS +L K I +K+ L + S + + +D D S++ +
Sbjct: 729 YSQQLAKANLKIDHLEKETSLLRQSEGSNVVFKGIDLPDGIAPSSASI------------ 776
Query: 122 ELKKQNEFQQEMLDDVQ---KKLVNLANSLE 149
+ QNE+ +L +++ KKL NL +SLE
Sbjct: 777 -INSQNEYLIHLLQELENKEKKLKNLEDSLE 806
Score = 28.5 bits (62), Expect = 9.5
Identities = 29/121 (23%), Positives = 60/121 (49%), Gaps = 7/121 (5%)
Query: 80 KKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQK 139
++ + L+++ + L E L+ A++ +L + Q+ +LK+ EF ++ +VQ+
Sbjct: 2056 QREQELQKENLKLSSENIELKFQLEQANKDLPRL---KNQVRDLKEMCEFLKKEKAEVQR 2112
Query: 140 KLVNLANS-LEGKVDKVLMRNLFISHFHMPKNQR-HEVLRLMGSILGVRREEMEQLFHDN 197
KL ++ S GK L + + + + K QR +E L+ IL E+M + +N
Sbjct: 2113 KLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGIL--TSEKMANIEQEN 2170
Query: 198 Q 198
+
Sbjct: 2171 E 2171
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 47.0 bits (110), Expect = 3e-05
Identities = 54/272 (19%), Positives = 130/272 (47%), Gaps = 40/272 (14%)
Query: 12 VESLQEQLNVVSKQRDETALLSASQQQVKQYALSLA-NLQMVLQHFQKEEKSMYSAELQK 70
+E ++ +++ ++ + +L + + +Q L N++M +++ +EE + EL+K
Sbjct: 1039 IEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIEN--QEELRLLGDELKK 1096
Query: 71 QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQ 130
Q++++A+ K A E ++ +RL E + E+L K +Q++E ++Q
Sbjct: 1097 QQEIVAQEKNHAIKKEGELSRTCDRLAEVE----------EKLKEKSQQLQEKQQQLLNV 1146
Query: 131 QEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPK-------NQRHEVLRLMGSIL 183
QE + ++QKK+ N +E +++ + L + H + N+ +E ++ SI
Sbjct: 1147 QEEMSEMQKKI----NEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVK---SIT 1199
Query: 184 GVRR--EEMEQLFHDNQGSVTRWM-----TGWLGRGSKSVPNTPLRPNQQSV--LNSSFS 234
R+ +E+++ F + + ++ TG + + + L+ +Q+++ L S S
Sbjct: 1200 KERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVS 1259
Query: 235 ECFVKFLETE----SHSSVPPPKLSVHDMKPL 262
E + + T+ SH+ + +H+ + L
Sbjct: 1260 EKTAQIINTQDLEKSHTKLQEEIPVLHEEQEL 1291
Score = 38.5 bits (88), Expect = 0.009
Identities = 35/182 (19%), Positives = 79/182 (43%), Gaps = 18/182 (9%)
Query: 15 LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQL 74
+Q L + K +D+ L+ +Q K N + + F+++ K M E ++ Q
Sbjct: 791 VQGLLEEIGKTKDD---LATTQSNYKSTDQEFQNFKTLHMDFEQKYK-MVLEENERMNQE 846
Query: 75 IAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEML 134
I K+A+ + + +L+ L L +R ++ + ++E+LK+Q E + L
Sbjct: 847 IVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQE---RLNEMEQLKEQLENRDSTL 903
Query: 135 DDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSILGVRREEMEQLF 194
V+++ + L+ +++V Q + L+ + L + R++++
Sbjct: 904 QTVEREKTLITEKLQQTLEEV-----------KTLTQEKDDLKQLQESLQIERDQLKSDI 952
Query: 195 HD 196
HD
Sbjct: 953 HD 954
Score = 37.4 bits (85), Expect = 0.020
Identities = 34/167 (20%), Positives = 74/167 (44%), Gaps = 16/167 (9%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQY-----ALSLANLQMVLQH 55
++N A V + L+ +L+ + LL + Q+K+ + L N++M L +
Sbjct: 559 LKNLVKHAEVYNQDLENELS------SKVELLREKEDQIKKLQEYIDSQKLENIKMDLSY 612
Query: 56 FQK--EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQL 113
+ E+ L + + + K+++ L + + L+E++ E ++ +
Sbjct: 613 SLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTY---KQMENDI 669
Query: 114 DLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNL 160
L + Q+E KK ++ L ++ L + ++GKV K L+ NL
Sbjct: 670 QLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNL 716
Score = 34.3 bits (77), Expect = 0.17
Identities = 34/159 (21%), Positives = 64/159 (40%), Gaps = 8/159 (5%)
Query: 2 ENASHQASVQVE--SLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE 59
EN SV E +L+ + +RD+ L S Q+ K L + + KE
Sbjct: 1879 ENLEEMKSVMKERDNLRRVEETLKLERDQ---LKESLQETKARDLEIQQELKTARMLSKE 1935
Query: 60 EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
K +K + + + L++ LQ+++ E R+ E +++ ++
Sbjct: 1936 HKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKK 1995
Query: 120 I---EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
I E+LKKQ E Q + V+ L L ++++
Sbjct: 1996 INEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEI 2034
Score = 33.5 bits (75), Expect = 0.29
Identities = 37/167 (22%), Positives = 77/167 (46%), Gaps = 29/167 (17%)
Query: 16 QEQLNVVS---KQRDETALLSASQQQVKQYALSLANLQMVLQHFQ----------KEEKS 62
QE+L +V K+ ET + + V + ++N+Q L+H +EE
Sbjct: 1720 QEELKIVHMHLKEHQET--IDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELR 1777
Query: 63 MYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASR---------LTEQL 113
+ L++Q++ I + + K+ ++Q+ L+ ++A L + +T +
Sbjct: 1778 IAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKK 1837
Query: 114 DLKEEQ-----IEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
D+ E Q +E+LKKQ + Q L ++ + +NLA L ++++
Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEM 1884
Score = 30.8 bits (68), Expect = 1.9
Identities = 48/233 (20%), Positives = 108/233 (46%), Gaps = 47/233 (20%)
Query: 15 LQEQLNVVSKQR----DETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYS--AEL 68
L+EQ +++ R ++ +S Q+Q++ L N + + ++KEE+ +E+
Sbjct: 1486 LKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQN--KIQEIYEKEEQFNIKQISEV 1543
Query: 69 QKQKQLIAEWK--KKA-----ESLERKVISLQERLDEADAAL-------DSASRLTEQLD 114
Q++ + ++K +KA +S+E K++ L RL E+ + + R+ E L
Sbjct: 1544 QEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQ 1603
Query: 115 LKEEQIEE--------LKKQNEFQQEML-----DDVQKKLVNLANSLEG-KVDKVLMRNL 160
++ +Q++E +K+ E + + L ++ Q+K+ + + E + K+ + N+
Sbjct: 1604 IERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENI 1663
Query: 161 FISHFHMPKNQRHEVLRLMGSILGVR----------REEMEQLFHDNQGSVTR 203
+ + + HE L M S+ R + E +QL + + ++TR
Sbjct: 1664 ETENIRLTQ-ILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITR 1715
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/125 (21%), Positives = 68/125 (54%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
++Q + +QR++ L +++ ++ A ++ + ++EE+ L+KQ++
Sbjct: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
Query: 76 AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
A+W ++ E +R++ + R++E A L ++ +L+ ++ +EL +Q + QQE L
Sbjct: 842 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 901
Query: 136 DVQKK 140
+Q++
Sbjct: 902 RLQQQ 906
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/134 (19%), Positives = 64/134 (47%), Gaps = 16/134 (11%)
Query: 15 LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE-------EKSMYSAE 67
+Q Q ++ +++ + L QQQ +Q L+ L Q+ + ++ AE
Sbjct: 883 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 942
Query: 68 LQK-----QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLT----EQLDLKEE 118
+QK ++QL E +++ L + + Q++ + + + S+ + L++++E
Sbjct: 943 IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002
Query: 119 QIEELKKQNEFQQE 132
+ +++KQ + QQ+
Sbjct: 1003 EARQMQKQQQQQQQ 1016
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/125 (21%), Positives = 68/125 (54%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
++Q + +QR++ L +++ ++ A ++ + ++EE+ L+KQ++
Sbjct: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868
Query: 76 AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
A+W ++ E +R++ + R++E A L ++ +L+ ++ +EL +Q + QQE L
Sbjct: 869 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 928
Query: 136 DVQKK 140
+Q++
Sbjct: 929 RLQQQ 933
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/134 (19%), Positives = 64/134 (47%), Gaps = 16/134 (11%)
Query: 15 LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE-------EKSMYSAE 67
+Q Q ++ +++ + L QQQ +Q L+ L Q+ + ++ AE
Sbjct: 910 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 969
Query: 68 LQK-----QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLT----EQLDLKEE 118
+QK ++QL E +++ L + + Q++ + + + S+ + L++++E
Sbjct: 970 IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029
Query: 119 QIEELKKQNEFQQE 132
+ +++KQ + QQ+
Sbjct: 1030 EARQMQKQQQQQQQ 1043
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/125 (21%), Positives = 68/125 (54%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
++Q + +QR++ L +++ ++ A ++ + ++EE+ L+KQ++
Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
Query: 76 AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
A+W ++ E +R++ + R++E A L ++ +L+ ++ +EL +Q + QQE L
Sbjct: 848 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 907
Query: 136 DVQKK 140
+Q++
Sbjct: 908 RLQQQ 912
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/134 (19%), Positives = 64/134 (47%), Gaps = 16/134 (11%)
Query: 15 LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE-------EKSMYSAE 67
+Q Q ++ +++ + L QQQ +Q L+ L Q+ + ++ AE
Sbjct: 889 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 948
Query: 68 LQK-----QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLT----EQLDLKEE 118
+QK ++QL E +++ L + + Q++ + + + S+ + L++++E
Sbjct: 949 IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
Query: 119 QIEELKKQNEFQQE 132
+ +++KQ + QQ+
Sbjct: 1009 EARQMQKQQQQQQQ 1022
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/125 (21%), Positives = 68/125 (54%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
++Q + +QR++ L +++ ++ A ++ + ++EE+ L+KQ++
Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847
Query: 76 AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
A+W ++ E +R++ + R++E A L ++ +L+ ++ +EL +Q + QQE L
Sbjct: 848 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 907
Query: 136 DVQKK 140
+Q++
Sbjct: 908 RLQQQ 912
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/134 (19%), Positives = 64/134 (47%), Gaps = 16/134 (11%)
Query: 15 LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE-------EKSMYSAE 67
+Q Q ++ +++ + L QQQ +Q L+ L Q+ + ++ AE
Sbjct: 889 VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 948
Query: 68 LQK-----QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLT----EQLDLKEE 118
+QK ++QL E +++ L + + Q++ + + + S+ + L++++E
Sbjct: 949 IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008
Query: 119 QIEELKKQNEFQQE 132
+ +++KQ + QQ+
Sbjct: 1009 EARQMQKQQQQQQQ 1022
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 46.6 bits (109), Expect = 3e-05
Identities = 37/153 (24%), Positives = 75/153 (49%), Gaps = 9/153 (5%)
Query: 5 SHQASVQVESLQEQLNVVSKQRDETALLSAS---QQQVKQYALSLANLQMVLQHFQKEEK 61
S + E+ +E+L QR++ LL+ + +QQ+++ + +A + + E +
Sbjct: 1465 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
Query: 62 SMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI- 120
+ S E K + +A+ KK+ LE KV +E LDE + + +L+++ E++
Sbjct: 1525 DISSQE-SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMR 1583
Query: 121 ----EELKKQNEFQQEMLDDVQKKLVNLANSLE 149
+E++ ++E +E QKKL + LE
Sbjct: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616
Score = 35.8 bits (81), Expect = 0.059
Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 55 HFQKEEKSMYSAELQKQKQLIAEWKKKAES-LERKVISLQERLDEADAALDSASRLTEQL 113
H Q ++ + L++Q + K + ++ LE + E + + AA+ ASR Q+
Sbjct: 1717 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1776
Query: 114 DLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLM 157
+ + Q+EE K+ + QE L +Q ++ L S+ VDK L+
Sbjct: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM---VDKSLV 1817
Score = 34.3 bits (77), Expect = 0.17
Identities = 38/173 (21%), Positives = 78/173 (45%), Gaps = 18/173 (10%)
Query: 5 SHQASVQVESLQEQ-----LNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQK 58
S +A +Q S QE L V KQ RD A + ++++ + A ++ L+ +
Sbjct: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577
Query: 59 EEKSM---YSAELQKQKQLIAEWKKKAES-LERKVISLQERLDEADAALDSASRLTEQLD 114
E + M +S E++ + + + E ++ + L++ + L+E ++ L L +L
Sbjct: 1578 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637
Query: 115 LKEEQI--------EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRN 159
+Q+ + L+K + + +L D Q L +L NS K + ++N
Sbjct: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690
Score = 34.3 bits (77), Expect = 0.17
Identities = 33/163 (20%), Positives = 76/163 (46%), Gaps = 17/163 (10%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQV----KQYALSLANLQMVLQHF 56
ME+ + +S Q++L + Q +E +Q+V ++ LA L +
Sbjct: 1590 MESRDEEVEEARQSCQKKLKQMEVQLEEEY---EDKQKVLREKRELEGKLATLSDQVNRR 1646
Query: 57 QKEEKSMYSAELQKQKQLIAEWK------KKAESLERKVISLQERLDEADAALDSASRLT 110
E + +L++ K L+A+ + K + +R++ L+ +L+E++ +A +
Sbjct: 1647 DFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKAR 1706
Query: 111 EQLDLKEE----QIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
+ ++++ E QI+++ K +E L +Q++ + N LE
Sbjct: 1707 KAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLE 1749
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 20/136 (14%)
Query: 11 QVESLQEQLNVVSKQRDETA-LLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ 69
Q+ LQ QL +K++ E L A Q QV+ S+ +KS+ S +
Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV------------DKSLVSRQEA 1822
Query: 70 KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEF 129
K ++L + + ++R + SL RL E + +LTE+ D + K+QN+
Sbjct: 1823 KIRELETRLEFERTQVKR-LESLASRLKE------NMEKLTEERDQRIAAENREKEQNKR 1875
Query: 130 QQEMLDDVQKKLVNLA 145
Q L D ++++ LA
Sbjct: 1876 LQRQLRDTKEEMGELA 1891
Score = 32.3 bits (72), Expect = 0.66
Identities = 26/149 (17%), Positives = 77/149 (51%), Gaps = 9/149 (6%)
Query: 11 QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQ----KEEKSMYSA 66
++++LQ Q+ + + + +L+S + ++++ L + ++ + + +++M
Sbjct: 1796 KLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKL 1855
Query: 67 ELQKQKQLIAEWKKKAES--LERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELK 124
++ +++ AE ++K ++ L+R++ +E + E ASR +L++ +E L+
Sbjct: 1856 TEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM---DLESLE 1912
Query: 125 KQNEFQQEMLDDVQKKLVNLANSLEGKVD 153
N+ Q L K++ +L ++E +++
Sbjct: 1913 AANQSLQADLKLAFKRIGDLQAAIEDEME 1941
Score = 30.0 bits (66), Expect = 3.3
Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 14/106 (13%)
Query: 59 EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERL-------DEADAALD--SASRL 109
EE ++L+K ++ E + ++ LE ++ L L + A LD +A RL
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
Query: 110 TEQLDLKE--EQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVD 153
+ ++KE Q + LKKQ E + ++ ++ +L+ A + G+VD
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVME--MEVMEARLIRAA-EINGEVD 1363
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 46.6 bits (109), Expect = 3e-05
Identities = 37/153 (24%), Positives = 75/153 (49%), Gaps = 9/153 (5%)
Query: 5 SHQASVQVESLQEQLNVVSKQRDETALLSAS---QQQVKQYALSLANLQMVLQHFQKEEK 61
S + E+ +E+L QR++ LL+ + +QQ+++ + +A + + E +
Sbjct: 1465 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
Query: 62 SMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI- 120
+ S E K + +A+ KK+ LE KV +E LDE + + +L+++ E++
Sbjct: 1525 DISSQE-SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMR 1583
Query: 121 ----EELKKQNEFQQEMLDDVQKKLVNLANSLE 149
+E++ ++E +E QKKL + LE
Sbjct: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616
Score = 35.8 bits (81), Expect = 0.059
Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 4/104 (3%)
Query: 55 HFQKEEKSMYSAELQKQKQLIAEWKKKAES-LERKVISLQERLDEADAALDSASRLTEQL 113
H Q ++ + L++Q + K + ++ LE + E + + AA+ ASR Q+
Sbjct: 1717 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1776
Query: 114 DLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLM 157
+ + Q+EE K+ + QE L +Q ++ L S+ VDK L+
Sbjct: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM---VDKSLV 1817
Score = 34.3 bits (77), Expect = 0.17
Identities = 38/173 (21%), Positives = 78/173 (45%), Gaps = 18/173 (10%)
Query: 5 SHQASVQVESLQEQ-----LNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQK 58
S +A +Q S QE L V KQ RD A + ++++ + A ++ L+ +
Sbjct: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577
Query: 59 EEKSM---YSAELQKQKQLIAEWKKKAES-LERKVISLQERLDEADAALDSASRLTEQLD 114
E + M +S E++ + + + E ++ + L++ + L+E ++ L L +L
Sbjct: 1578 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637
Query: 115 LKEEQI--------EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRN 159
+Q+ + L+K + + +L D Q L +L NS K + ++N
Sbjct: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690
Score = 34.3 bits (77), Expect = 0.17
Identities = 33/163 (20%), Positives = 76/163 (46%), Gaps = 17/163 (10%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQV----KQYALSLANLQMVLQHF 56
ME+ + +S Q++L + Q +E +Q+V ++ LA L +
Sbjct: 1590 MESRDEEVEEARQSCQKKLKQMEVQLEEEY---EDKQKVLREKRELEGKLATLSDQVNRR 1646
Query: 57 QKEEKSMYSAELQKQKQLIAEWK------KKAESLERKVISLQERLDEADAALDSASRLT 110
E + +L++ K L+A+ + K + +R++ L+ +L+E++ +A +
Sbjct: 1647 DFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKAR 1706
Query: 111 EQLDLKEE----QIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
+ ++++ E QI+++ K +E L +Q++ + N LE
Sbjct: 1707 KAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLE 1749
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 20/136 (14%)
Query: 11 QVESLQEQLNVVSKQRDETA-LLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ 69
Q+ LQ QL +K++ E L A Q QV+ S+ +KS+ S +
Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV------------DKSLVSRQEA 1822
Query: 70 KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEF 129
K ++L + + ++R + SL RL E + +LTE+ D + K+QN+
Sbjct: 1823 KIRELETRLEFERTQVKR-LESLASRLKE------NMEKLTEERDQRIAAENREKEQNKR 1875
Query: 130 QQEMLDDVQKKLVNLA 145
Q L D ++++ LA
Sbjct: 1876 LQRQLRDTKEEMGELA 1891
Score = 32.7 bits (73), Expect = 0.50
Identities = 34/202 (16%), Positives = 93/202 (46%), Gaps = 15/202 (7%)
Query: 11 QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQ----KEEKSMYSA 66
++++LQ Q+ + + + +L+S + ++++ L + ++ + + +++M
Sbjct: 1796 KLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKL 1855
Query: 67 ELQKQKQLIAEWKKKAES--LERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELK 124
++ +++ AE ++K ++ L+R++ +E + E ASR +L++ +E L+
Sbjct: 1856 TEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM---DLESLE 1912
Query: 125 KQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSILG 184
N+ Q L K++ +L ++E +++ +L S M + +L G
Sbjct: 1913 AANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGD--- 1969
Query: 185 VRREEMEQLFHDNQGSVTRWMT 206
+++ D V W++
Sbjct: 1970 ---SDVDSELEDRVDGVKSWLS 1988
Score = 30.0 bits (66), Expect = 3.3
Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 14/106 (13%)
Query: 59 EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERL-------DEADAALD--SASRL 109
EE ++L+K ++ E + ++ LE ++ L L + A LD +A RL
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
Query: 110 TEQLDLKE--EQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVD 153
+ ++KE Q + LKKQ E + ++ ++ +L+ A + G+VD
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVME--MEVMEARLIRAA-EINGEVD 1363
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/157 (26%), Positives = 87/157 (55%), Gaps = 26/157 (16%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
EN S + V+ E+L+++L ++ ++ E + + S Q+ Q ++ H ++E+
Sbjct: 791 ENLSEVSQVK-ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKL-------HQKEEQF 842
Query: 62 SMYSAELQKQKQLIAEWKKK---AESLERKVISLQERLDEADAAL-----DSASRLT--- 110
+M S++L+K ++ +A+ + K + E ++I +E+L+ A + D++S+LT
Sbjct: 843 NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMN 902
Query: 111 EQLDLKEEQIEELK----KQNE---FQQEMLDDVQKK 140
++L LKE +EEL+ K NE F Q+ ++D+ K
Sbjct: 903 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 939
Score = 39.3 bits (90), Expect = 0.005
Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 26/148 (17%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQ--------RDETALLSASQQQVKQYALSLANLQMV 52
+ AS + +++ L++QL KQ E++ S+ ++++ L L NLQ
Sbjct: 733 LRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN 792
Query: 53 LQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQ 112
L + ++++ ELQ K+ AE ++A S++R S+QE +++
Sbjct: 793 LSEVSQVKETL-EKELQILKEKFAEASEEAVSVQR---SMQETVNK-------------- 834
Query: 113 LDLKEEQIEELKKQNEFQQEMLDDVQKK 140
L KEEQ L E +E L D++ K
Sbjct: 835 LHQKEEQFNMLSSDLEKLRENLADMEAK 862
Score = 38.1 bits (87), Expect = 0.012
Identities = 36/174 (20%), Positives = 81/174 (46%), Gaps = 15/174 (8%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDET--ALLSASQQQVKQYALSLANLQMVLQH--FQ 57
E A+H + ++E+L+ +L V K+++ + A+ S + Q+ + + + LQ +
Sbjct: 638 ERAAH--AKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIK 695
Query: 58 KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
+E + A+ +Q ++I + + ++ E K++ L + +L +QL+ E
Sbjct: 696 VKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAE 755
Query: 118 EQIEELKKQNEFQQEMLDDVQK-------KLVNLANSLE--GKVDKVLMRNLFI 162
+QI+ L+ + + + + KL NL +L +V + L + L I
Sbjct: 756 KQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 809
Score = 34.7 bits (78), Expect = 0.13
Identities = 35/158 (22%), Positives = 66/158 (41%), Gaps = 3/158 (1%)
Query: 36 QQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQER 95
+Q K A A M + +EK+ A L+ KQ A+ + + ++L+ + E
Sbjct: 1031 KQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 1090
Query: 96 LDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
L+++ L ++ E+ ++IE LK+ + + L +Q++ V LA L D+V
Sbjct: 1091 LNKSKELLTVENQKMEEF---RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV 1147
Query: 156 LMRNLFISHFHMPKNQRHEVLRLMGSILGVRREEMEQL 193
+ NQ E+ + + EE L
Sbjct: 1148 TSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1185
Score = 29.3 bits (64), Expect = 5.6
Identities = 22/138 (15%), Positives = 67/138 (48%), Gaps = 6/138 (4%)
Query: 9 SVQVESLQEQLNVVSKQRDETAL-LSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAE 67
S Q+ + ++L + + +E L L+ + + S+ ++ + + Q+E + E
Sbjct: 895 SSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 954
Query: 68 LQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL-----DSASRLTEQLDLKEEQIEE 122
++ ++ +++ +KK E+ + L+ R + A + + L + L E++++
Sbjct: 955 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 1014
Query: 123 LKKQNEFQQEMLDDVQKK 140
+++N + L++++K+
Sbjct: 1015 AREENSGLLQELEELRKQ 1032
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 46.2 bits (108), Expect = 4e-05
Identities = 42/157 (26%), Positives = 87/157 (55%), Gaps = 26/157 (16%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
EN S + V+ E+L+++L ++ ++ E + + S Q+ Q ++ H ++E+
Sbjct: 826 ENLSEVSQVK-ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKL-------HQKEEQF 877
Query: 62 SMYSAELQKQKQLIAEWKKK---AESLERKVISLQERLDEADAAL-----DSASRLT--- 110
+M S++L+K ++ +A+ + K + E ++I +E+L+ A + D++S+LT
Sbjct: 878 NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMN 937
Query: 111 EQLDLKEEQIEELK----KQNE---FQQEMLDDVQKK 140
++L LKE +EEL+ K NE F Q+ ++D+ K
Sbjct: 938 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 974
Score = 39.3 bits (90), Expect = 0.005
Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 26/148 (17%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQ--------RDETALLSASQQQVKQYALSLANLQMV 52
+ AS + +++ L++QL KQ E++ S+ ++++ L L NLQ
Sbjct: 768 LRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN 827
Query: 53 LQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQ 112
L + ++++ ELQ K+ AE ++A S++R S+QE +++
Sbjct: 828 LSEVSQVKETL-EKELQILKEKFAEASEEAVSVQR---SMQETVNK-------------- 869
Query: 113 LDLKEEQIEELKKQNEFQQEMLDDVQKK 140
L KEEQ L E +E L D++ K
Sbjct: 870 LHQKEEQFNMLSSDLEKLRENLADMEAK 897
Score = 38.1 bits (87), Expect = 0.012
Identities = 36/174 (20%), Positives = 81/174 (46%), Gaps = 15/174 (8%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDET--ALLSASQQQVKQYALSLANLQMVLQH--FQ 57
E A+H + ++E+L+ +L V K+++ + A+ S + Q+ + + + LQ +
Sbjct: 673 ERAAH--AKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIK 730
Query: 58 KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
+E + A+ +Q ++I + + ++ E K++ L + +L +QL+ E
Sbjct: 731 VKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAE 790
Query: 118 EQIEELKKQNEFQQEMLDDVQK-------KLVNLANSLE--GKVDKVLMRNLFI 162
+QI+ L+ + + + + KL NL +L +V + L + L I
Sbjct: 791 KQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 844
Score = 34.7 bits (78), Expect = 0.13
Identities = 35/158 (22%), Positives = 66/158 (41%), Gaps = 3/158 (1%)
Query: 36 QQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQER 95
+Q K A A M + +EK+ A L+ KQ A+ + + ++L+ + E
Sbjct: 1066 KQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 1125
Query: 96 LDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
L+++ L ++ E+ ++IE LK+ + + L +Q++ V LA L D+V
Sbjct: 1126 LNKSKELLTVENQKMEEF---RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV 1182
Query: 156 LMRNLFISHFHMPKNQRHEVLRLMGSILGVRREEMEQL 193
+ NQ E+ + + EE L
Sbjct: 1183 TSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1220
Score = 29.3 bits (64), Expect = 5.6
Identities = 22/138 (15%), Positives = 67/138 (48%), Gaps = 6/138 (4%)
Query: 9 SVQVESLQEQLNVVSKQRDETAL-LSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAE 67
S Q+ + ++L + + +E L L+ + + S+ ++ + + Q+E + E
Sbjct: 930 SSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 989
Query: 68 LQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL-----DSASRLTEQLDLKEEQIEE 122
++ ++ +++ +KK E+ + L+ R + A + + L + L E++++
Sbjct: 990 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 1049
Query: 123 LKKQNEFQQEMLDDVQKK 140
+++N + L++++K+
Sbjct: 1050 AREENSGLLQELEELRKQ 1067
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 46.2 bits (108), Expect = 4e-05
Identities = 39/168 (23%), Positives = 79/168 (47%), Gaps = 20/168 (11%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQ----VKQYAL----SLANLQMV 52
+E + + Q++ ++ Q + ++RDE L QQQ +K L SL ++
Sbjct: 142 LEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQE 201
Query: 53 LQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQ 112
L+ + E S EL Q+ ++ +K E L+R +L+E+ D A+ A
Sbjct: 202 LEA-RTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITA 260
Query: 113 LDLKEEQIEELKKQ-----------NEFQQEMLDDVQKKLVNLANSLE 149
L+ KE++++ L +Q + +++++ +Q+K+ +L LE
Sbjct: 261 LEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLE 308
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/197 (21%), Positives = 87/197 (44%), Gaps = 26/197 (13%)
Query: 5 SHQASVQVESLQEQLNVVSKQRDET-ALLSASQQQVKQYALSLANLQMVLQHFQKEEKSM 63
S S ++E LQ + + +QRD A + ++ ++ LQ ++Q + + +
Sbjct: 223 SSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKV 282
Query: 64 YSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEEL 123
+AE Q+++ +I L+ KV SL++RL EQ EE ++EL
Sbjct: 283 -TAETQEKEDVITH-------LQEKVASLEKRL--------------EQNLSGEEHVQEL 320
Query: 124 KKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSIL 183
K+ ++ L+D +++L+ +S ++ + R + E L+ I+
Sbjct: 321 LKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETR---VRELEQTLQASEEQLQQSKGIV 377
Query: 184 GVRREEMEQLFHDNQGS 200
+ ++++L NQ S
Sbjct: 378 AAQETQIQELAAANQES 394
Score = 31.6 bits (70), Expect = 1.1
Identities = 47/256 (18%), Positives = 99/256 (38%), Gaps = 42/256 (16%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
+N + V ++ QE L + ++ +ALL Q Q + AL + ++E+
Sbjct: 512 QNLREKTEVLLQKEQEILQL--ERGHNSALLQIHQLQAELEALRTLKAEEAAVVAEQEDL 569
Query: 62 SMYSAELQKQKQLIAEWKKKAESLERKVISLQE--RLDEADA-ALDSASRLTEQLDLKEE 118
LQ + + E + +++ V L R + A+D E+ DL+++
Sbjct: 570 LRLRGPLQAEALSVNESHVTSRAMQDPVFQLPTAGRTPNGEVGAMDLTQLQKEKQDLEQQ 629
Query: 119 QIEELKKQNEFQQEMLD------------------DVQKK----LVNLANSLEGKVDKV- 155
+E+ K + QQ ML+ +V++K + N+A S+ D
Sbjct: 630 LLEKNKTIKQMQQRMLELRKTLQKELKIRPDNELFEVREKPGPEMANMAPSVTNNTDLTD 689
Query: 156 -------LMRNLFISHFHMPKNQRHEVLRLMGSILGVRREEMEQLFHDNQGSVTRWMTGW 208
++++ + +++ +++ + +L +EE L + W
Sbjct: 690 AREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENML-----KETLEYKMSW 744
Query: 209 LGRGSKSVPNTPLRPN 224
GSK P +RP+
Sbjct: 745 F--GSKPAPKGSIRPS 758
Score = 30.8 bits (68), Expect = 1.9
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 41 QYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEAD 100
+Y SL N Q L+ KEE S Q + E +K+ E +++ +L +DE +
Sbjct: 453 EYERSLQNHQFELKKL-KEEWSQREIVSVAMAQALEEVRKQREEFQQQAANLTAIIDEKE 511
Query: 101 AALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKL 141
L TE L KE++I +L++ + + +Q +L
Sbjct: 512 QNL---REKTEVLLQKEQEILQLERGHNSALLQIHQLQAEL 549
Score = 30.4 bits (67), Expect = 2.5
Identities = 26/119 (21%), Positives = 56/119 (47%), Gaps = 9/119 (7%)
Query: 18 QLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAE 77
+ +V+ +R A + ++Q ++Q A L+ +++ ++ + EL+K K+ E
Sbjct: 416 EAQIVALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQN-HQFELKKLKE---E 471
Query: 78 WKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEE-----LKKQNEFQQ 131
W ++ +L+E + + A+ LT +D KE+ + E L+K+ E Q
Sbjct: 472 WSQREIVSVAMAQALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQ 530
>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
Length = 388
Score = 45.8 bits (107), Expect = 6e-05
Identities = 45/164 (27%), Positives = 72/164 (43%), Gaps = 16/164 (9%)
Query: 5 SHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMY 64
SHQ S+ E LQE L D+ + K+ A L + F++E K
Sbjct: 72 SHQKSI--EQLQETLRQ-KLLSDDNWKEKIEAELAKERAQHLVEFEEQALLFKEETKLQL 128
Query: 65 SAELQKQKQLIAEWKKKAESLERKVISL---------QERLDEADAALDSASRLTEQLDL 115
E +K + +I ++KK+ E L+ K+ L QE + S +R TE+ +
Sbjct: 129 DIEKEKHQDVIQKYKKEQEELQMKISDLITGATRDLRQEVTTLKEKLHKSHTRYTEESNS 188
Query: 116 KEEQIEELKK-QNEFQQEM---LDDVQKKLVNLANSLEGKVDKV 155
KE++IE LK EF+ + +D NL +E K D++
Sbjct: 189 KEKEIENLKNLVAEFESRLKKEIDSNDSVSENLRKEMEQKSDEL 232
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 44.7 bits (104), Expect = 1e-04
Identities = 35/147 (23%), Positives = 68/147 (46%), Gaps = 16/147 (10%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
++ Q + + + Q +L+ VS + + L QQ+ Q+ S N K E
Sbjct: 682 LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNEL-------KSE 734
Query: 61 KSMYSAELQKQKQL---IAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
K S LQ+++QL E + +SL R++ +E++ + L+ + KE
Sbjct: 735 KLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQE------KE 788
Query: 118 EQIEELKKQNEFQQEMLDDVQKKLVNL 144
E I + N+ Q+ L+D+++K+ N+
Sbjct: 789 ELINKKNTSNKIAQDKLNDIKEKVKNI 815
Score = 36.6 bits (83), Expect = 0.035
Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 28 ETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLER 87
++ +LS Q ++K L L+ + ++ + AE + K AE E+L+
Sbjct: 307 KSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSK---AEKNSNVETLKM 363
Query: 88 KVISLQERLDEADAALDSASRLTEQLD---LKEEQIEELKKQNEFQQEMLDDVQKKLVNL 144
+VISLQ + D L + EQL+ Q+E L K + E + ++ + +
Sbjct: 364 EVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDE 423
Query: 145 ANSLEG 150
SL G
Sbjct: 424 LTSLLG 429
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 44.7 bits (104), Expect = 1e-04
Identities = 35/147 (23%), Positives = 68/147 (46%), Gaps = 16/147 (10%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
++ Q + + + Q +L+ VS + + L QQ+ Q+ S N K E
Sbjct: 821 LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNEL-------KSE 873
Query: 61 KSMYSAELQKQKQL---IAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
K S LQ+++QL E + +SL R++ +E++ + L+ + KE
Sbjct: 874 KLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQE------KE 927
Query: 118 EQIEELKKQNEFQQEMLDDVQKKLVNL 144
E I + N+ Q+ L+D+++K+ N+
Sbjct: 928 ELINKKNTSNKIAQDKLNDIKEKVKNI 954
Score = 36.6 bits (83), Expect = 0.035
Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 28 ETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLER 87
++ +LS Q ++K L L+ + ++ + AE + K AE E+L+
Sbjct: 446 KSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSK---AEKNSNVETLKM 502
Query: 88 KVISLQERLDEADAALDSASRLTEQLD---LKEEQIEELKKQNEFQQEMLDDVQKKLVNL 144
+VISLQ + D L + EQL+ Q+E L K + E + ++ + +
Sbjct: 503 EVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDE 562
Query: 145 ANSLEG 150
SL G
Sbjct: 563 LTSLLG 568
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 44.7 bits (104), Expect = 1e-04
Identities = 31/147 (21%), Positives = 72/147 (48%), Gaps = 6/147 (4%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
M Q Q E ++EQ + KQ+++T + +Q +Q ++ + +++E
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERK--VISLQERLDEADAAL----DSASRLTEQLD 114
+ M E Q KQ W++K + E+K + +E++ E + + + + EQ+
Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376
Query: 115 LKEEQIEELKKQNEFQQEMLDDVQKKL 141
+EEQ+ + ++Q Q+E + + ++++
Sbjct: 377 KQEEQMRKQEEQMRKQEEQMGEQKEQM 403
Score = 43.5 bits (101), Expect = 3e-04
Identities = 25/134 (18%), Positives = 69/134 (51%), Gaps = 4/134 (2%)
Query: 7 QASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA 66
Q Q E + EQ + KQ ++ + ++Q+++ + + +Q Q+E+
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQ---MGEQEEQMRKQEEQMGEQEEQVQK-QEEQVQKQEE 255
Query: 67 ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQ 126
+++KQ++ + E +++ E +++ +E+ ++ + + ++ EQ + EQ E++++Q
Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315
Query: 127 NEFQQEMLDDVQKK 140
E +E + + K+
Sbjct: 316 EEQMREQEEQMGKQ 329
Score = 34.7 bits (78), Expect = 0.13
Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 11/138 (7%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQ--K 58
M Q Q E ++EQ + KQ ++ + K+ QM Q Q +
Sbjct: 305 MREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE--------QMWKQEEQMGE 356
Query: 59 EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEE 118
+E+ M E Q +KQ + +K+ E + ++ ++++ ++ + EQ+ +EE
Sbjct: 357 QEEQMQKQEEQVRKQE-EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEE 415
Query: 119 QIEELKKQNEFQQEMLDD 136
Q+ E K+Q Q+E + +
Sbjct: 416 QMGEQKEQMRKQEEHMGE 433
Score = 32.7 bits (73), Expect = 0.50
Identities = 32/195 (16%), Positives = 87/195 (44%), Gaps = 11/195 (5%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
M+ Q Q E +++Q + +Q ++ Q+Q +Q ++ + +++E
Sbjct: 215 MQKQEEQMGEQEEQMRKQEEQMGEQEEQV------QKQEEQVQKQEEQMRKQEEQMREQE 268
Query: 61 KSMYSAELQ--KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEE 118
+ M E Q KQK+ + ++ E E+ ++ ++ + + ++ EQ + +
Sbjct: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328
Query: 119 QIEELKKQNE---FQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEV 175
Q E++ +Q E Q+E + ++++ ++ + ++V + + ++ E
Sbjct: 329 QEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Query: 176 LRLMGSILGVRREEM 190
+R +G ++E+M
Sbjct: 389 MRKQEEQMGEQKEQM 403
Score = 32.0 bits (71), Expect = 0.86
Identities = 26/147 (17%), Positives = 69/147 (46%), Gaps = 15/147 (10%)
Query: 7 QASVQVESLQEQLNVVSKQ----RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKS 62
Q Q ++EQ V +Q R++ + + QV++ + + + Q+E+
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE-QEEQMG 209
Query: 63 MYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEE 122
++QKQ++ + E +++ E ++ +E++ + + EQ+ +EEQ+ +
Sbjct: 210 EQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE----------EQVQKQEEQMRK 259
Query: 123 LKKQNEFQQEMLDDVQKKLVNLANSLE 149
++Q Q+E + + +++++ E
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTE 286
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 44.7 bits (104), Expect = 1e-04
Identities = 33/135 (24%), Positives = 66/135 (48%), Gaps = 12/135 (8%)
Query: 26 RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESL 85
+++T LL V + +LQ LQ +K+ +++ + + + Q IA+ K+ E L
Sbjct: 2010 KEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ-IAQLNKEKELL 2068
Query: 86 ERKVISLQERLDEAD-----------AALDSASRLTEQLDLKEEQIEELKKQNEFQQEML 134
++ SLQ RL E+D AAL +L +E++ +L++ E + +
Sbjct: 2069 VKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRI 2128
Query: 135 DDVQKKLVNLANSLE 149
+ +KK +++A L+
Sbjct: 2129 EADEKKQLHIAEKLK 2143
Score = 38.9 bits (89), Expect = 0.007
Identities = 31/141 (21%), Positives = 64/141 (45%), Gaps = 16/141 (11%)
Query: 11 QVESLQEQLNVVSKQRDE-TALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA--E 67
+++ + NV+ + D+ T++ + ++++ L + Q Q +E + + E
Sbjct: 424 ELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEE 483
Query: 68 LQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQN 127
++K+ L+ K +E R+V L+ L L+ + E E+K +N
Sbjct: 484 MKKENNLL---KSHSEQKAREVCHLEAELKNIKQCLNQSQNFAE----------EMKAKN 530
Query: 128 EFQQEMLDDVQKKLVNLANSL 148
Q+ ML D+Q+K+ NSL
Sbjct: 531 TSQETMLRDLQEKINQQENSL 551
Score = 37.7 bits (86), Expect = 0.016
Identities = 40/197 (20%), Positives = 88/197 (44%), Gaps = 33/197 (16%)
Query: 5 SHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMY 64
S ++ ++E+ Q N Q +L + + Q + + + ++Q + E+++
Sbjct: 809 SERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLM 868
Query: 65 SAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASR----LTEQLDLKEEQI 120
AE Q + +AE ++ L+ + Q + E +AL++ + L ++++ ++ +I
Sbjct: 869 KAE-QMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEI 927
Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
+ELKK N ++ L ++Q L++ SLE K M
Sbjct: 928 QELKKSNHLLEDSLKELQ--LLSETLSLEKKE--------------------------MS 959
Query: 181 SILGVRREEMEQLFHDN 197
SI+ + + E+E+L +N
Sbjct: 960 SIISLNKREIEELTQEN 976
Score = 35.8 bits (81), Expect = 0.059
Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 16/159 (10%)
Query: 7 QASVQVESLQEQLNVVS------KQRDETALLSASQ---QQVKQYALSLANLQMVLQHFQ 57
QAS + +L+++L ++ +Q E+A S Q ++ K++ L+ Q Q
Sbjct: 352 QASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLD 411
Query: 58 KE---EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLD 114
+E K+ + ELQ+ K + + + + L L+ L+E L A + +
Sbjct: 412 QECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQ 471
Query: 115 LKEEQI----EELKKQNEFQQEMLDDVQKKLVNLANSLE 149
+KE ++ EE+KK+N + + +++ +L L+
Sbjct: 472 IKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELK 510
Score = 35.8 bits (81), Expect = 0.059
Identities = 40/172 (23%), Positives = 77/172 (44%), Gaps = 24/172 (13%)
Query: 7 QASVQVESLQEQLN-----VVSKQRDETALLSASQQ---QVKQYALSLANLQMVLQHFQK 58
++S +E LQ QL V + D+ A + Q QV+ L A L L K
Sbjct: 2435 KSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDE-AK 2493
Query: 59 EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRL--------T 110
+ + + Q + + K+K E + ++ L+ ++ + + + S++
Sbjct: 2494 NNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKE 2553
Query: 111 EQLDLK------EEQIEELKKQNEFQQEMLDDVQKKLVNLANSLE-GKVDKV 155
+ L+L+ E++I+ L+ +N Q+ L+ +Q NL N LE K+DK+
Sbjct: 2554 QNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKM 2605
Score = 35.0 bits (79), Expect = 0.10
Identities = 28/114 (24%), Positives = 61/114 (53%), Gaps = 6/114 (5%)
Query: 37 QQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERL 96
Q++++ L L+ Q Q + S+ +A LQKQKQ + K + +L+R+ +RL
Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAA-LQKQKQKVENEKTEGTNLKRE----NQRL 72
Query: 97 DEADAALD-SASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
E +L+ + +++ +L +KE Q+ + Q ++ ++ ++++L + LE
Sbjct: 73 MEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELE 126
Score = 33.5 bits (75), Expect = 0.29
Identities = 41/195 (21%), Positives = 82/195 (42%), Gaps = 18/195 (9%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQ--HFQKE 59
EN + + E +SK +++T SA Q V + +L N + LQ + + E
Sbjct: 865 ENLMKAEQMHQSFVAETSQRISKLQEDT---SAHQNVVAETLSALENKEKELQLLNDKVE 921
Query: 60 EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
+ EL+K L+ + K+ + L + +SL+++ ++ + L + +
Sbjct: 922 TEQAEIQELKKSNHLLEDSLKELQLLS-ETLSLEKK------------EMSSIISLNKRE 968
Query: 120 IEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLM 179
IEEL ++N +E+ + ++ +NL E + + R IS Q +L
Sbjct: 969 IEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQR 1028
Query: 180 GSILGVRREEMEQLF 194
G E++ Q +
Sbjct: 1029 CEETGNAYEDLSQKY 1043
Score = 32.3 bits (72), Expect = 0.66
Identities = 30/160 (18%), Positives = 74/160 (46%), Gaps = 11/160 (6%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE- 59
+++ S Q + +V L+ +L + + L+ SQ ++ + + +L+ Q++
Sbjct: 491 LKSHSEQKAREVCHLEAELKNIKQ------CLNQSQNFAEEMKAKNTSQETMLRDLQEKI 544
Query: 60 EKSMYSAELQKQKQLIAEWKKKAES----LERKVISLQERLDEADAALDSASRLTEQLDL 115
+ S L+K K +A+ +K+ + L+++ +++ D+ + L L+L
Sbjct: 545 NQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALEL 604
Query: 116 KEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
K+++ EELK++ + +K L + + E K+
Sbjct: 605 KKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKI 644
Score = 32.0 bits (71), Expect = 0.86
Identities = 38/163 (23%), Positives = 77/163 (47%), Gaps = 28/163 (17%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
E+ S QA + ES E+LNV + L A+ + ++AL L++ Q
Sbjct: 2071 ESESLQARLS-ESDYEKLNV-------SKALEAALVEKGEFALRLSSTQ----------- 2111
Query: 62 SMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEA----DAALDSASRLTEQLDLKE 117
E+ + ++ I + + + E+ E+K + + E+L E D+ D L +L + E
Sbjct: 2112 ----EEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSE 2167
Query: 118 EQIEELKKQNEFQQEMLDDVQKKLVNLANSLE-GKVDKVLMRN 159
E E + E + ++ ++ ++ +A SL+ ++D V +R+
Sbjct: 2168 ENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210
Score = 31.6 bits (70), Expect = 1.1
Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 14/140 (10%)
Query: 15 LQEQLNVV-SKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQ 73
L++++ V+ SK L Q K L +M F ++ M + E + Q++
Sbjct: 2565 LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQRE 2624
Query: 74 LIAEWKKKAESLERKVISLQERLD-EADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
+ + +K LQE L E + L E++ ++Q++EL +N ++
Sbjct: 2625 M--------HEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKK 2676
Query: 133 MLDDVQKKLVNLANSLEGKV 152
LD + K V EGKV
Sbjct: 2677 SLDCMHKDQV----EKEGKV 2692
Score = 29.6 bits (65), Expect = 4.3
Identities = 19/83 (22%), Positives = 43/83 (51%), Gaps = 3/83 (3%)
Query: 73 QLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
Q I E + + + L+++ Q +LD +AAL + E ++ + LK++N+ E
Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVEN---EKTEGTNLKRENQRLME 74
Query: 133 MLDDVQKKLVNLANSLEGKVDKV 155
+ + ++K +++ L+ K +V
Sbjct: 75 ICESLEKTKQKISHELQVKESQV 97
Score = 29.3 bits (64), Expect = 5.6
Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 8/135 (5%)
Query: 11 QVESLQEQLNVVSKQRDET--ALLSASQQQVKQYAL---SLANLQMVLQHFQKEEKSMYS 65
+++S ++QL ++ + E +L + QV++ +A Q+ L +K+ +++
Sbjct: 2656 EIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALL- 2714
Query: 66 AELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKK 125
L KQ E + E L K L + E D S L L + +EELKK
Sbjct: 2715 --LDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 2772
Query: 126 QNEFQQEMLDDVQKK 140
+ ++ ++K+
Sbjct: 2773 TKMDNLKYVNQLKKE 2787
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 44.3 bits (103), Expect = 2e-04
Identities = 34/160 (21%), Positives = 77/160 (48%), Gaps = 14/160 (8%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
+E+ + ++ L+ L V K++ A++ +VK +A L ++ KE+
Sbjct: 943 LEDECSELKRDIDDLELTLAKVEKEKH------ATENKVKNLTEEMAGLDEIIAKLTKEK 996
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
K++ A Q L AE + K +L + + L++++D+ + +L+ ++ L+ + ++
Sbjct: 997 KALQEAHQQALDDLQAE-EDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL 1055
Query: 121 E-ELKKQNEF------QQEMLDDVQKKLVNLANSLEGKVD 153
E +LK E ++ LD+ KK N+L +++
Sbjct: 1056 EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095
Score = 42.4 bits (98), Expect = 6e-04
Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 36/200 (18%)
Query: 1 MENASHQASVQVESLQ---EQLNVVS-----KQRDETALLSASQQQVKQYALSLANLQMV 52
+E H+ ++E L E+ N + KQR+ +L+ +Q+ ++ Q
Sbjct: 1414 LEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEES-------QSE 1466
Query: 53 LQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQ 112
L+ QKE +S+ S EL K K E + E+ +R+ +LQE + + LTEQ
Sbjct: 1467 LESSQKEARSL-STELFKLKNAYEESLEHLETFKRENKNLQEEISD----------LTEQ 1515
Query: 113 LDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQR 172
L + I EL+K + + ++Q L SLE + K+L L + ++
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575
Query: 173 HEVLRLMGSILGVRREEMEQ 192
L + EEMEQ
Sbjct: 1576 ----------LAEKDEEMEQ 1585
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/127 (23%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Query: 7 QASVQVESLQEQ-LNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYS 65
+ S +V+ L Q +++++++ A LS Q +V++ N + + + +M +
Sbjct: 1708 ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK-AITDAAMMA 1766
Query: 66 AELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKK 125
EL+K++ A ++ +++E+ + LQ RLDEA+ + +QL E ++ EL+
Sbjct: 1767 EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGK--KQLQKLEARVRELEN 1824
Query: 126 QNEFQQE 132
+ E +Q+
Sbjct: 1825 ELEAEQK 1831
Score = 39.7 bits (91), Expect = 0.004
Identities = 51/238 (21%), Positives = 95/238 (39%), Gaps = 46/238 (19%)
Query: 1 MENASHQASVQVE----------SLQEQLNVVSKQRDETA--LLSASQQQVKQYALSLAN 48
+E A SVQ+E ++ L + Q + TA L V + + N
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN 1209
Query: 49 LQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASR 108
LQ V Q +KE KS + EL + + K +LE+ +L+++++E + + R
Sbjct: 1210 LQRVKQKLEKE-KSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQR 1268
Query: 109 ------------------LTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEG 150
L+ QLD KE I +L + + L+D++++L
Sbjct: 1269 SVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL--------- 1319
Query: 151 KVDKVLMRNLFISHFHMPKNQRH--EVLRLMGSILGVRREEMEQLFHDNQGSVTRWMT 206
++V +N H ++ RH ++LR + E++++ V +W T
Sbjct: 1320 -EEEVKAKNALA---HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373
Score = 38.9 bits (89), Expect = 0.007
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 34/156 (21%)
Query: 11 QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ- 69
Q+E L+ QL K ++ A +AL A L Q EE++ AELQ
Sbjct: 1311 QLEDLKRQLEEEVKAKNALA-----------HALQSARHDCDLLREQYEEETEAKAELQR 1359
Query: 70 ---KQKQLIAEWKKK--------AESLERKVISLQERLDEADAALDSASRLTEQLDLKEE 118
K +A+W+ K E LE L +RL EA+ A+++ + L+ +
Sbjct: 1360 VLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKH 1419
Query: 119 QIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDK 154
++ QNE + M+D V +N+ +DK
Sbjct: 1420 RL-----QNEIEDLMVD------VERSNAAAAALDK 1444
Score = 35.4 bits (80), Expect = 0.077
Identities = 30/150 (20%), Positives = 72/150 (48%), Gaps = 10/150 (6%)
Query: 7 QASVQVESLQEQLNVVSKQRDE-TALLSASQQQVKQYALSLANLQMVLQHFQKEEKSM-- 63
Q +V+ + E+L + E TA + + + + +L++ L +KE+ +
Sbjct: 914 QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATEN 973
Query: 64 ----YSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
+ E+ ++IA+ K+ ++L+ + Q+ LD+ A D + LT+ E+Q
Sbjct: 974 KVKNLTEEMAGLDEIIAKLTKEKKALQE---AHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030
Query: 120 IEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
+++L+ E ++++ D+++ L L+
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060
Score = 35.4 bits (80), Expect = 0.077
Identities = 30/153 (19%), Positives = 74/153 (48%), Gaps = 11/153 (7%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
++ A QA +++ ++++N ++K + + +QQV SL + V ++ +
Sbjct: 999 LQEAHQQALDDLQAEEDKVNTLTKAKVKL------EQQVDDLEGSLEQEKKVRMDLERAK 1052
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLK---- 116
+ + +L+ ++ I + + + L+ ++ L+ +A ++ L QL K
Sbjct: 1053 RKL-EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKEL 1111
Query: 117 EEQIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
+ +IEEL+++ E ++ V+K +L+ LE
Sbjct: 1112 QARIEELEEELEAERTARAKVEKLRSDLSRELE 1144
Score = 33.5 bits (75), Expect = 0.29
Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 22/133 (16%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQKE 59
+EN Q +++ +LN ++ + DE AL S Q+++K+ + L+
Sbjct: 1069 LENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE--------- 1119
Query: 60 EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
EL+ ++ A+ +K L R++ + ERL+EA A + Q+++ +++
Sbjct: 1120 ------EELEAERTARAKVEKLRSDLSRELEEISERLEEAGGA------TSVQIEMNKKR 1167
Query: 120 IEELKKQNEFQQE 132
E +K +E
Sbjct: 1168 EAEFQKMRRDLEE 1180
Score = 32.3 bits (72), Expect = 0.66
Identities = 37/208 (17%), Positives = 86/208 (41%), Gaps = 26/208 (12%)
Query: 7 QASVQVESLQEQLNVVSKQRDETAL--------LSASQQQVKQYALSLANLQMVLQHFQK 58
+A QV+SLQ L Q D+ ++ +++ L L+ V++ ++
Sbjct: 1638 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697
Query: 59 EEK-----------------SMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADA 101
K S ++ + ++K++ A+ + +E V + ++A
Sbjct: 1698 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK 1757
Query: 102 ALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLF 161
A+ A+ + E+L +++ L++ + ++ + D+Q +L + A + K K ++ L
Sbjct: 1758 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-DEAEQIALKGGKKQLQKLE 1816
Query: 162 ISHFHMPKNQRHEVLRLMGSILGVRREE 189
+ E R S+ G+R+ E
Sbjct: 1817 ARVRELENELEAEQKRNAESVKGMRKSE 1844
Score = 30.0 bits (66), Expect = 3.3
Identities = 25/111 (22%), Positives = 50/111 (45%), Gaps = 15/111 (13%)
Query: 57 QKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISL--------------QERLDEADAA 102
+KE SM E + K+ + + + + + LE K++SL Q+ L +A+
Sbjct: 846 EKEMASM-KEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER 904
Query: 103 LDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVD 153
D + QL+ K +++ E + E L ++KL + + L+ +D
Sbjct: 905 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDID 955
Score = 30.0 bits (66), Expect = 3.3
Identities = 26/119 (21%), Positives = 53/119 (44%), Gaps = 7/119 (5%)
Query: 11 QVESLQEQLNVVSKQRDETAL----LSASQQQVKQYALSLANLQMVLQHFQKE---EKSM 63
QV+ L+ L K R + L + ++ + L N + L K+ E +
Sbjct: 1030 QVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNA 1089
Query: 64 YSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEE 122
+A ++ ++ L ++ +KK + L+ ++ L+E L+ A +L L + E+I E
Sbjct: 1090 LNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1148
Score = 28.9 bits (63), Expect = 7.3
Identities = 30/161 (18%), Positives = 69/161 (42%), Gaps = 5/161 (3%)
Query: 4 ASHQASVQVESLQE----QLNVVSKQRDETALLSASQQQV-KQYALSLANLQMVLQHFQK 58
A A +VE L+ +L +S++ +E ++ Q ++ K+ ++ L+
Sbjct: 1124 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1183
Query: 59 EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEE 118
+ ++ +A +K +AE ++ ++L+R L++ E LD + EQ+ +
Sbjct: 1184 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1243
Query: 119 QIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRN 159
+E++ + E Q ++ N L + K+ N
Sbjct: 1244 NLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN 1284
Score = 28.5 bits (62), Expect = 9.5
Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 18/171 (10%)
Query: 3 NASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANL-----QMVLQHFQ 57
NA +A + + K++D +A L ++ ++Q L + Q+ L+ +
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGK 1809
Query: 58 KEEKSMYSA------ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTE 111
K+ + + + EL+ +++ AE K ER++ L + +E L L +
Sbjct: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869
Query: 112 QLDLK----EEQIEELKKQNEFQQEMLDDVQKKL---VNLANSLEGKVDKV 155
+L LK + Q EE ++Q VQ +L A+ E +V+K+
Sbjct: 1870 KLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 1920
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
sapiens]
Length = 1116
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/162 (23%), Positives = 79/162 (48%), Gaps = 16/162 (9%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQR-DETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
++ S +A +V+ L E L V ++ D+ ++ ++QVK +ANL+ Q +K+
Sbjct: 748 KDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKS 807
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDL----- 115
M +++ L ++ +SL +K +R++E + AL + ++T + ++
Sbjct: 808 AQMLEEARRREDNLNDSSQQLQDSLRKK----DDRIEELEEALRESVQITAEREMVLAQE 863
Query: 116 ------KEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGK 151
E+Q+EEL E ++ L+ ++ KL + SL K
Sbjct: 864 ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEK 905
Score = 39.3 bits (90), Expect = 0.005
Identities = 42/172 (24%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQK-- 58
+ N + +E L+E L + A+L Q +V L L + +L K
Sbjct: 492 LTNQFSDSKQHIEVLKESLTA---KEQRAAIL---QTEVDALRLRLEEKETMLNKKTKQI 545
Query: 59 ----EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDS--------- 105
EEK + E+ K ++ ++K L++K+ +LQE+L + + + S
Sbjct: 546 QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 605
Query: 106 ---------ASRLTEQLDLKEEQIEELKKQNE----FQQEMLDDVQKKLVNL 144
+ L E L KE IE LK+Q + +QE +D+ +K L +L
Sbjct: 606 ADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDL 657
Score = 31.6 bits (70), Expect = 1.1
Identities = 43/211 (20%), Positives = 89/211 (42%), Gaps = 33/211 (15%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
+E+ Q + L+E+++ + ++A A Q ++ +++++ L+ ++E
Sbjct: 346 LESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE- 404
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
++ K ++ +++ E + +V + + + +L E+L KE Q
Sbjct: 405 -----IQMLKSNGALSTEEREEEMKQMEVYRSHSKFMK-----NKVEQLKEELSSKEAQW 454
Query: 121 EELKKQ--------NEFQQEM------LDDVQKKLVNLANSLEGKVD--KVLMRNLFISH 164
EELKK+ + +QE+ L +Q KL L N +VL +L
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESL---- 510
Query: 165 FHMPKNQRHEVLRLMGSILGVRREEMEQLFH 195
K QR +L+ L +R EE E + +
Sbjct: 511 --TAKEQRAAILQTEVDALRLRLEEKETMLN 539
Score = 31.6 bits (70), Expect = 1.1
Identities = 34/163 (20%), Positives = 75/163 (46%), Gaps = 16/163 (9%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYA-LSLANLQMVLQHFQKE 59
++++ + ++E L+E L + E ++ A ++ + A + L M ++ ++E
Sbjct: 828 LQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQE 887
Query: 60 EKSMYSAELQKQKQLIAE------------WKKKAESLERKVISLQERLDEADAALDSAS 107
+SM A+L +Q +AE K E LE K +L + E DA + +
Sbjct: 888 LESM-KAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI-ALL 945
Query: 108 RLTEQLDLKEEQIEELKKQNE-FQQEMLDDVQKKLVNLANSLE 149
L+ +E++ LK++ + Q++ Q ++ +A++ E
Sbjct: 946 ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYE 988
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/162 (23%), Positives = 79/162 (48%), Gaps = 16/162 (9%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQR-DETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
++ S +A +V+ L E L V ++ D+ ++ ++QVK +ANL+ Q +K+
Sbjct: 720 KDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKS 779
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDL----- 115
M +++ L ++ +SL +K +R++E + AL + ++T + ++
Sbjct: 780 AQMLEEARRREDNLNDSSQQLQDSLRKK----DDRIEELEEALRESVQITAEREMVLAQE 835
Query: 116 ------KEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGK 151
E+Q+EEL E ++ L+ ++ KL + SL K
Sbjct: 836 ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEK 877
Score = 39.3 bits (90), Expect = 0.005
Identities = 42/172 (24%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQK-- 58
+ N + +E L+E L + A+L Q +V L L + +L K
Sbjct: 464 LTNQFSDSKQHIEVLKESLTA---KEQRAAIL---QTEVDALRLRLEEKETMLNKKTKQI 517
Query: 59 ----EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDS--------- 105
EEK + E+ K ++ ++K L++K+ +LQE+L + + + S
Sbjct: 518 QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 577
Query: 106 ---------ASRLTEQLDLKEEQIEELKKQNE----FQQEMLDDVQKKLVNL 144
+ L E L KE IE LK+Q + +QE +D+ +K L +L
Sbjct: 578 ADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDL 629
Score = 31.6 bits (70), Expect = 1.1
Identities = 34/163 (20%), Positives = 75/163 (46%), Gaps = 16/163 (9%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYA-LSLANLQMVLQHFQKE 59
++++ + ++E L+E L + E ++ A ++ + A + L M ++ ++E
Sbjct: 800 LQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQE 859
Query: 60 EKSMYSAELQKQKQLIAE------------WKKKAESLERKVISLQERLDEADAALDSAS 107
+SM A+L +Q +AE K E LE K +L + E DA + +
Sbjct: 860 LESM-KAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI-ALL 917
Query: 108 RLTEQLDLKEEQIEELKKQNE-FQQEMLDDVQKKLVNLANSLE 149
L+ +E++ LK++ + Q++ Q ++ +A++ E
Sbjct: 918 ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYE 960
Score = 30.0 bits (66), Expect = 3.3
Identities = 46/226 (20%), Positives = 94/226 (41%), Gaps = 40/226 (17%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQ--- 57
+E + + ES+++ L ++ + L + + ++ + LA +M + H +
Sbjct: 295 IETQKQTLNARDESIKKLLEMLQSK----GLSAKATEEDHERTRRLAEAEMHVHHLESLL 350
Query: 58 ---KEEKSMYSAELQ------------KQKQLIAEWK-KKAESLERKVISLQERLD--EA 99
++E SM E+ K Q + E K K S+ER + L+E + ++
Sbjct: 351 EQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKS 410
Query: 100 DAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV--LM 157
+ AL TE+ + + +Q+E + ++F + + V+++L L K+ L
Sbjct: 411 NGALS-----TEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLT 465
Query: 158 RNLFISHFHM--------PKNQRHEVLRLMGSILGVRREEMEQLFH 195
S H+ K QR +L+ L +R EE E + +
Sbjct: 466 NQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLN 511
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 23/175 (13%)
Query: 1 MENASHQASVQVESLQEQLNVVSK-------QRDETA-LLSASQQQVKQYALSLANLQMV 52
MEN H + +++ L++ +V + + DE LL A Q ++Q L +
Sbjct: 937 MENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQ 996
Query: 53 LQHFQKEEKSMYS-----AELQKQKQLIAEW--KKKAESLERKVISLQERLDEADAALDS 105
++H Q+ EK M EL+K+ Q I + AE ++ K LQE + D+
Sbjct: 997 VRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDT 1056
Query: 106 ASRLTEQLDLKEEQIEELK--------KQNEFQQEMLDDVQKKLVNLANSLEGKV 152
+L +L LKE + +E+K +Q E + +L+ + L + L K+
Sbjct: 1057 RCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKI 1111
Score = 37.4 bits (85), Expect = 0.020
Identities = 42/174 (24%), Positives = 81/174 (46%), Gaps = 19/174 (10%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSAS-QQQVKQYALSLANLQ--MVLQHFQ 57
+E + Q ++SL EQ R E + L+ Q + Y + LA L+ M ++ Q
Sbjct: 1078 LEESRAQQKETLKSLLEQ--ETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQ 1135
Query: 58 ---------KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALD--SA 106
+EE ++ AEL K L + + ++L+ ++I LQ +LD +AL+
Sbjct: 1136 CISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKD 1195
Query: 107 SRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNL 160
++T+Q + E I+ L+K +Q+++ ++ L L + D+ + L
Sbjct: 1196 EKITQQEEKYEAIIQNLEKD---RQKLVSSQEQDREQLIQKLNCEKDEAIQTAL 1246
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 43.9 bits (102), Expect = 2e-04
Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 23/175 (13%)
Query: 1 MENASHQASVQVESLQEQLNVVSK-------QRDETA-LLSASQQQVKQYALSLANLQMV 52
MEN H + +++ L++ +V + + DE LL A Q ++Q L +
Sbjct: 937 MENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQ 996
Query: 53 LQHFQKEEKSMYS-----AELQKQKQLIAEW--KKKAESLERKVISLQERLDEADAALDS 105
++H Q+ EK M EL+K+ Q I + AE ++ K LQE + D+
Sbjct: 997 VRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDT 1056
Query: 106 ASRLTEQLDLKEEQIEELK--------KQNEFQQEMLDDVQKKLVNLANSLEGKV 152
+L +L LKE + +E+K +Q E + +L+ + L + L K+
Sbjct: 1057 RCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKI 1111
Score = 37.4 bits (85), Expect = 0.020
Identities = 42/174 (24%), Positives = 81/174 (46%), Gaps = 19/174 (10%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSAS-QQQVKQYALSLANLQ--MVLQHFQ 57
+E + Q ++SL EQ R E + L+ Q + Y + LA L+ M ++ Q
Sbjct: 1078 LEESRAQQKETLKSLLEQ--ETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQ 1135
Query: 58 ---------KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALD--SA 106
+EE ++ AEL K L + + ++L+ ++I LQ +LD +AL+
Sbjct: 1136 CISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKD 1195
Query: 107 SRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNL 160
++T+Q + E I+ L+K +Q+++ ++ L L + D+ + L
Sbjct: 1196 EKITQQEEKYEAIIQNLEKD---RQKLVSSQEQDREQLIQKLNCEKDEAIQTAL 1246
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 43.9 bits (102), Expect = 2e-04
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 11/135 (8%)
Query: 2 ENASHQASVQVESLQEQLNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
E + ++Q+ +L E L V K+ + +S ++Q +A L+ +Q+ Q E
Sbjct: 1233 EENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDER 1292
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
+++ L+ + ++ E L+ KV+ LQ +LD AA+ R + L +K Q
Sbjct: 1293 RALLERCLKGEGEI--------EKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQA 1344
Query: 121 EELK--KQNEFQQEM 133
K + NE Q M
Sbjct: 1345 LNRKWAEDNEVQNCM 1359
Score = 37.4 bits (85), Expect = 0.020
Identities = 38/166 (22%), Positives = 77/166 (46%), Gaps = 15/166 (9%)
Query: 15 LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAE--LQKQK 72
LQ QL+ +Q E L S + A + +L+ VL+ +++ + + E LQK K
Sbjct: 479 LQHQLDKTKQQHQEQQALQQSTTAKLREAQN--DLEQVLRQIGDKDQKIQNLEALLQKSK 536
Query: 73 QLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEE----LKKQNE 128
+ I+ +K+ E L K+ + E + A+ ++L E+ +EQ+ + LK Q+E
Sbjct: 537 ENISLLEKEREDLYAKI-----QAGEGETAV--LNQLQEKNHTLQEQVTQLTEKLKNQSE 589
Query: 129 FQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHE 174
++ +++ ++ L D+VL ++ + N+ E
Sbjct: 590 SHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKE 635
Score = 36.6 bits (83), Expect = 0.035
Identities = 40/155 (25%), Positives = 72/155 (46%), Gaps = 28/155 (18%)
Query: 22 VSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSM------YSAELQKQKQLI 75
V+ R E L AS ++ K Y+ L Q Q++E SAELQ +Q +
Sbjct: 85 VTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQL 144
Query: 76 AE--------------WKKKAESLERKVISLQERLDEA----DAALDSASRLTEQLDLKE 117
E +++KA L ++ ++ + DE +AA +RLTE+L+ +
Sbjct: 145 EEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEA 204
Query: 118 EQIEELKKQNEFQQEMLDDV---QKKLVNLANSLE 149
I++LK + Q+ ++DV +K+LV + ++
Sbjct: 205 TVIQDLKTE-LLQRPGIEDVAVLKKELVQVQTLMD 238
Score = 36.6 bits (83), Expect = 0.035
Identities = 42/186 (22%), Positives = 84/186 (45%), Gaps = 15/186 (8%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
Q Q N+ + +++ A L A+Q +V S+ L L KE+ S +++ + +L+
Sbjct: 593 QAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNE-SKEKVSQLDIQIKAKTELL 651
Query: 76 --AEWKKKAES------LERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQ- 126
AE K A+ L+ +LQ++ E + ++T +L K+E +L+
Sbjct: 652 LSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHL 711
Query: 127 NEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSILGVR 186
E++++ L QK LEG++ K+ +L + Q + R + + L +R
Sbjct: 712 KEYKEKYLSLEQK-----TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELR 766
Query: 187 REEMEQ 192
E+ +
Sbjct: 767 ATELSK 772
Score = 36.2 bits (82), Expect = 0.045
Identities = 36/158 (22%), Positives = 71/158 (44%), Gaps = 26/158 (16%)
Query: 2 ENASHQASVQVESLQEQL----NVVSKQRDETALLSASQQQVKQYA-------------L 44
+ ASHQ +++ S+QEQL N + + E L + ++KQ + L
Sbjct: 923 KEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGEL 982
Query: 45 SLANLQMV-LQHFQKEEKSMYSAELQKQKQLIA----EWKKKAESLERKVISLQERLDEA 99
+A LQ L++ +++ + + EL +K+ I+ ++K E+ ++ R E
Sbjct: 983 KIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESEL 1042
Query: 100 DAALDSASRLTEQLDLKEEQI----EELKKQNEFQQEM 133
A + E+L L +E + ++ QN+ QE+
Sbjct: 1043 LATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQEL 1080
Score = 35.8 bits (81), Expect = 0.059
Identities = 31/147 (21%), Positives = 69/147 (46%), Gaps = 1/147 (0%)
Query: 11 QVESLQEQLNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ 69
++ +++++L+ VS ++ + Q+ K L L L+H + + E +
Sbjct: 854 ELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQK 913
Query: 70 KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEF 129
+ K+ + + K+ + L+ ++ S+QE+L +A L + +QL ++++ +Q +
Sbjct: 914 ELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKK 973
Query: 130 QQEMLDDVQKKLVNLANSLEGKVDKVL 156
Q E L K V LE K+ + L
Sbjct: 974 QIEALQGELKIAVLQKTELENKLQQQL 1000
Score = 35.4 bits (80), Expect = 0.077
Identities = 33/168 (19%), Positives = 75/168 (44%), Gaps = 32/168 (19%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDE-TALLSASQQQ-------VKQYALSLANLQMV 52
++N A ++ Q++LN ++ Q D+ TA L Q+ +K+Y +L+
Sbjct: 665 LQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQK 724
Query: 53 LQHFQ-------------KEEKSMYSAELQKQKQLIAEWKKKAESL------ERKVIS-- 91
+ + K K +LQ+Q+QL + + +A L E++++S
Sbjct: 725 TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSST 784
Query: 92 ---LQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDD 136
LQ++ + ++ ++ E+ + ++ E L ++ + Q E L++
Sbjct: 785 RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNN 832
Score = 32.7 bits (73), Expect = 0.50
Identities = 34/152 (22%), Positives = 67/152 (44%), Gaps = 10/152 (6%)
Query: 7 QASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYAL-----SLANLQMVLQHFQKE-- 59
Q ++ L +L +Q E Q+Q+ L +A+LQ+ L +++
Sbjct: 411 QLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLK 470
Query: 60 EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
EK S ELQ Q + ++ ++L++ S +L EA L+ R D K +
Sbjct: 471 EKVTNSTELQHQLDKTKQQHQEQQALQQ---STTAKLREAQNDLEQVLRQIGDKDQKIQN 527
Query: 120 IEELKKQNEFQQEMLDDVQKKLVNLANSLEGK 151
+E L ++++ +L+ ++ L + EG+
Sbjct: 528 LEALLQKSKENISLLEKEREDLYAKIQAGEGE 559
Score = 32.3 bits (72), Expect = 0.66
Identities = 30/134 (22%), Positives = 58/134 (43%), Gaps = 27/134 (20%)
Query: 10 VQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQK--EEKSMYSAE 67
VQV++L + + + ++R+ L ++ QYA S A + + K +E ++Y E
Sbjct: 231 VQVQTLMDNMTL-ERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQE 289
Query: 68 LQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQN 127
LQK K + E +K ++L TE L KE+ +L++++
Sbjct: 290 LQKLKSSVNELTQKNQTL------------------------TENLLKKEQDYTKLEEKH 325
Query: 128 EFQQEMLDDVQKKL 141
+ ++Q L
Sbjct: 326 NEESVSKKNIQATL 339
Score = 31.6 bits (70), Expect = 1.1
Identities = 30/154 (19%), Positives = 74/154 (48%), Gaps = 19/154 (12%)
Query: 9 SVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLA--------NLQMVLQHFQKEE 60
S ++ES++E N+ +D LL + +++ A SL N Q++ +KEE
Sbjct: 1149 SHKLESIKEITNL----KDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEE 1204
Query: 61 KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
+ + ++K+ +L +E K+K +++ + + + A ++ + ++ + ++
Sbjct: 1205 EELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRV 1264
Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDK 154
EL+KQ DD++ ++ L +++ D+
Sbjct: 1265 SELEKQT-------DDLRGEIAVLEATVQNNQDE 1291
Score = 31.2 bits (69), Expect = 1.5
Identities = 37/158 (23%), Positives = 64/158 (40%), Gaps = 22/158 (13%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRD-----ETALLSASQQQVKQYALSLANLQMVLQH 55
+++ + S+ E L N + Q +TA + Q K+ L LQ
Sbjct: 1049 LKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQ-QLQERCKALQD 1107
Query: 56 FQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDL 115
QKE KS+ EL +K +AE ++ E+++ L E L L+S +T D
Sbjct: 1108 IQKE-KSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL--KSHKLESIKEITNLKDA 1164
Query: 116 KE-------------EQIEELKKQNEFQQEMLDDVQKK 140
K+ + ++ +Q + Q++L D KK
Sbjct: 1165 KQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKK 1202
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 43.5 bits (101), Expect = 3e-04
Identities = 42/190 (22%), Positives = 93/190 (48%), Gaps = 17/190 (8%)
Query: 15 LQEQLNVVSKQRDETAL-LSASQQQVKQYALSLAN--LQMVLQHFQKEEKSMYSAELQKQ 71
LQE+L +V ++ E L + ++++++ L L LQ H KE +S+ SA+LQ Q
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV-SAKLQAQ 284
Query: 72 KQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQ 131
+ W + + E K+ +E++ E + + E++ +EE+I E +++ Q+
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE---EKIREQEEKIREQEEKMRRQE 341
Query: 132 EMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSILGVRRE--- 188
EM+ + ++K+ + K +K+ + + ++ E +R ++ + E
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW-------EKEEKMRRQEEMMWEKEEKIR 394
Query: 189 EMEQLFHDNQ 198
E+E+ H+ +
Sbjct: 395 ELEEKMHEQE 404
Score = 39.3 bits (90), Expect = 0.005
Identities = 28/130 (21%), Positives = 68/130 (52%), Gaps = 15/130 (11%)
Query: 11 QVESLQEQLNVVSKQ----RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA 66
Q E +QEQ + +Q R++ + ++++ + + + + Q++E++M+
Sbjct: 617 QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE---EKMQEQEETMW-- 671
Query: 67 ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL-DSASRLTEQLDLKEEQIEELKK 125
+Q++ I E +KK E K+ +E + E + + + ++ EQ + +EQ E++++
Sbjct: 672 ---RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 728
Query: 126 QNE--FQQEM 133
Q E ++QE+
Sbjct: 729 QEEKMWEQEV 738
Score = 37.4 bits (85), Expect = 0.020
Identities = 24/130 (18%), Positives = 71/130 (54%), Gaps = 5/130 (3%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
QE++ K++++ + ++++++ + + ++ Q+E++ ++ KQ++ I
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE-QEEKRQEQEEKMWKQEEKI 614
Query: 76 AEWKKKAESLERKVISLQERL-DEADAALDSASRLTEQLDLKEEQIEELKKQNEF---QQ 131
E ++K + E K+ +E++ ++ + + ++ EQ + EQ E++++Q E Q+
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674
Query: 132 EMLDDVQKKL 141
E + + +KK+
Sbjct: 675 EKIREQEKKI 684
Score = 35.4 bits (80), Expect = 0.077
Identities = 23/134 (17%), Positives = 65/134 (48%), Gaps = 3/134 (2%)
Query: 57 QKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLK 116
Q+E+ ++ +Q++ I E ++K + E K+ +E++ E + + E++ +
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE---EKIREQ 631
Query: 117 EEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVL 176
EE+I E ++ + Q+E + + ++K+ ++ + + + + I ++ E +
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
Query: 177 RLMGSILGVRREEM 190
R ++ + E+M
Sbjct: 692 REQEEMMQEQEEKM 705
Score = 34.7 bits (78), Expect = 0.13
Identities = 43/179 (24%), Positives = 83/179 (46%), Gaps = 32/179 (17%)
Query: 2 ENASHQASVQV---ESLQEQLNVVS-KQRDETALLSASQQQVKQYALSL--------ANL 49
+NA Q +Q+ E + QLNV K++ E A L QQQ++ A L A L
Sbjct: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281
Query: 50 QMVLQHF-------QKEEKSMYSAE---------LQKQKQLIAEWKKKAESLERKVISLQ 93
Q ++ Q++E+ M+ E +Q+Q++ I E ++K E K+ +
Sbjct: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341
Query: 94 ERLDEADAALDSASRL----TEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSL 148
E + E + + + E++ +EE + E +++ Q+EM+ + ++K+ L +
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400
Score = 34.7 bits (78), Expect = 0.13
Identities = 28/139 (20%), Positives = 72/139 (51%), Gaps = 16/139 (11%)
Query: 11 QVESLQEQLNVVSKQ----RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA 66
Q E QEQ + KQ R++ + ++++++ + + + Q ++EEK
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ--EQEEK----- 648
Query: 67 ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL-DSASRLTEQLDLKEEQIEELKK 125
+ +Q++ + E ++K + E + +E++ E + + + ++ EQ ++ +EQ E++ +
Sbjct: 649 -MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707
Query: 126 QNEF---QQEMLDDVQKKL 141
Q E Q+E + + ++K+
Sbjct: 708 QEEKMCEQEEKMQEQEEKM 726
Score = 33.9 bits (76), Expect = 0.23
Identities = 26/152 (17%), Positives = 75/152 (49%), Gaps = 7/152 (4%)
Query: 11 QVESLQEQLNVVSKQRDETALLSAS-QQQVKQYALSLANLQMVLQHFQKEEKSMYSAE-- 67
Q E ++EQ V +Q ++ Q+Q ++ ++ + Q++E+ + E
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634
Query: 68 LQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL----DSASRLTEQLDLKEEQIEEL 123
+++Q+++ E ++K E K+ +E++ E + + + +++ +EE+I E
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694
Query: 124 KKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
++ + Q+E + + ++K+ ++ + +K+
Sbjct: 695 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 726
Score = 31.6 bits (70), Expect = 1.1
Identities = 27/129 (20%), Positives = 63/129 (48%), Gaps = 16/129 (12%)
Query: 11 QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQK 70
Q E ++EQ K R + ++ ++++++ + + + +++E+ M+ E +
Sbjct: 326 QEEKIREQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKE---EKMRRQEEMMWEKEEKM 379
Query: 71 QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQ 130
++Q W+K E K+ L+E++ E + R E+ +EE+I E +K+ E +
Sbjct: 380 RRQEEMMWEK-----EEKIRELEEKMHEQEKI-----REQEEKRQEEEKIREQEKRQEQE 429
Query: 131 QEMLDDVQK 139
+M +K
Sbjct: 430 AKMWRQEEK 438
Score = 31.2 bits (69), Expect = 1.5
Identities = 22/117 (18%), Positives = 57/117 (48%), Gaps = 3/117 (2%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
QE++ K++++ + ++ +Q + +M H Q+E+ ++ +Q++ I
Sbjct: 463 QEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM---HEQEEKIRKQEEKVWRQEEKI 519
Query: 76 AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
E ++K E K+ +E++ E + ++ EQ + EE+ + ++ ++QE
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Score = 30.4 bits (67), Expect = 2.5
Identities = 26/145 (17%), Positives = 72/145 (49%), Gaps = 10/145 (6%)
Query: 11 QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQK 70
Q E + EQ + KQ ++ + ++++++ + + + +++EEK E+ +
Sbjct: 494 QKEKMHEQEEKIRKQEEK---VWRQEEKIREQEEKIREQEEKM--WRQEEKIREQEEMWR 548
Query: 71 QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQ 130
+++ + E +K E +R QE+ D+ + E++ +EE+I E +++ + Q
Sbjct: 549 EEEKMHEQEKIWEEEKR-----QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ 603
Query: 131 QEMLDDVQKKLVNLANSLEGKVDKV 155
+E + ++K+ ++ + +K+
Sbjct: 604 EEKMWKQEEKIREQEEKIQEQEEKI 628
Score = 29.3 bits (64), Expect = 5.6
Identities = 30/157 (19%), Positives = 73/157 (46%), Gaps = 12/157 (7%)
Query: 1 MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
+E A + Q + + ++K+RD +L + Y ++ + ++ ++ + +E
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKERDALSL--------ELYRNTITDEELKEKNAKLQE 228
Query: 61 KSMYSAELQKQKQL-IAEWKKKAESLERKVISLQERLD-EADAALDSASRLTEQLDLKEE 118
K + + QL + E K+K E K++ Q++L EAD ++ +L + E
Sbjct: 229 KLQLVESEKSEIQLNVKELKRKLE--RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286
Query: 119 QIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
+ E + N+ Q+E + ++K+ ++ + +K+
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 323
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/129 (20%), Positives = 63/129 (48%), Gaps = 8/129 (6%)
Query: 16 QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQK---EEKSMYSAELQKQK 72
QE++ ++R E + +++ +Q A + + + +K +EK M+ +Q+
Sbjct: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW-----RQE 457
Query: 73 QLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
+ I E +K E +R+ R +E + R E++ +EE+I + +++ Q+E
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517
Query: 133 MLDDVQKKL 141
+ + ++K+
Sbjct: 518 KIREQEEKI 526
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,268,110
Number of Sequences: 37866
Number of extensions: 640120
Number of successful extensions: 6270
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 259
Number of HSP's successfully gapped in prelim test: 649
Number of HSP's that attempted gapping in prelim test: 3374
Number of HSP's gapped (non-prelim): 2802
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.