Guide to the Human Genome
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Search of human proteins with 169203883

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169203883 PREDICTED: hypothetical protein [Homo sapiens]
         (352 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169204908 PREDICTED: similar to Thyroid hormone receptor inte...   690   0.0  
gi|169205597 PREDICTED: similar to Thyroid hormone receptor inte...   690   0.0  
gi|169203883 PREDICTED: hypothetical protein [Homo sapiens]           690   0.0  
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]    614   e-176
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ...    52   8e-07
gi|221139761 zinc finger protein 853 [Homo sapiens]                    49   9e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    47   2e-05
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 47   3e-05
gi|71061468 centromere protein E [Homo sapiens]                        47   3e-05
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    47   3e-05
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap...    47   3e-05
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap...    47   3e-05
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi...    47   3e-05
gi|42794779 myosin 18A isoform b [Homo sapiens]                        47   3e-05
gi|28416946 myosin 18A isoform a [Homo sapiens]                        47   3e-05
gi|38044112 restin isoform b [Homo sapiens]                            46   4e-05
gi|4506751 restin isoform a [Homo sapiens]                             46   4e-05
gi|4504063 golgin 97 [Homo sapiens]                                    46   4e-05
gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]        46   6e-05
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]                     45   1e-04
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]                     45   1e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    45   1e-04
gi|55770834 centromere protein F [Homo sapiens]                        45   1e-04
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    44   2e-04
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    44   2e-04
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    44   2e-04
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo...    44   2e-04
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo...    44   2e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             44   2e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    44   3e-04

>gi|169204908 PREDICTED: similar to Thyroid hormone receptor
           interactor 11 [Homo sapiens]
          Length = 352

 Score =  690 bits (1781), Expect = 0.0
 Identities = 352/352 (100%), Positives = 352/352 (100%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE
Sbjct: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60

Query: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
           KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI
Sbjct: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120

Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
           EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG
Sbjct: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180

Query: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240
           SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF
Sbjct: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240

Query: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300
           LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS
Sbjct: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300

Query: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
           AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ
Sbjct: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352


>gi|169205597 PREDICTED: similar to Thyroid hormone receptor
           interactor 11 [Homo sapiens]
          Length = 352

 Score =  690 bits (1781), Expect = 0.0
 Identities = 352/352 (100%), Positives = 352/352 (100%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE
Sbjct: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60

Query: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
           KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI
Sbjct: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120

Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
           EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG
Sbjct: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180

Query: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240
           SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF
Sbjct: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240

Query: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300
           LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS
Sbjct: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300

Query: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
           AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ
Sbjct: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352


>gi|169203883 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 352

 Score =  690 bits (1781), Expect = 0.0
 Identities = 352/352 (100%), Positives = 352/352 (100%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE
Sbjct: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60

Query: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
           KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI
Sbjct: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120

Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
           EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG
Sbjct: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180

Query: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240
           SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF
Sbjct: 181 SILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVKF 240

Query: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300
           LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS
Sbjct: 241 LETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPRS 300

Query: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
           AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ
Sbjct: 301 AAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352


>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
          Length = 1979

 Score =  614 bits (1584), Expect = e-176
 Identities = 315/353 (89%), Positives = 332/353 (94%), Gaps = 1/353 (0%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRDETAL-LSASQQQVKQYALSLANLQMVLQHFQKE 59
            MENASHQASVQVESLQEQLNVVSKQRDETAL LS SQ+QVKQYALSLANLQMVL+HFQ+E
Sbjct: 1627 MENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQE 1686

Query: 60   EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
            EK+MYSAEL+KQKQLIAEWKK AE+LE KVISLQE LDEA+AALDSASRLTEQLD+KEEQ
Sbjct: 1687 EKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQ 1746

Query: 120  IEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLM 179
            IEELK+QNE +QEMLDDVQKKL++LANS EGKVDKVLMRNLFI HFH PKNQRHEVLRLM
Sbjct: 1747 IEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLM 1806

Query: 180  GSILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNSSFSECFVK 239
            GSILGVRREEMEQLFHD+QG VTRWMTGWLG GSKSVPNTPLRPNQQSV+NSSFSE FVK
Sbjct: 1807 GSILGVRREEMEQLFHDDQGGVTRWMTGWLGGGSKSVPNTPLRPNQQSVVNSSFSELFVK 1866

Query: 240  FLETESHSSVPPPKLSVHDMKPLESPGRRKLDTNAPESFKDTAESRSGRRREVNSVLAPR 299
            FLETESH S+PPPKLSVHDMKPL+SPGRRK DTNAPESFKDTAESRSGRR +VN  LAPR
Sbjct: 1867 FLETESHPSIPPPKLSVHDMKPLDSPGRRKRDTNAPESFKDTAESRSGRRTDVNPFLAPR 1926

Query: 300  SAAVPLINPAGLGPGGPQHLLLKPISDVWPTFTPLPVLPDNSAGVVLKDLGKQ 352
            SAAVPLINPAGLGPGGP HLLLKPISDV PTFTPLP LPDNSAGVVLKDL KQ
Sbjct: 1927 SAAVPLINPAGLGPGGPGHLLLKPISDVLPTFTPLPALPDNSAGVVLKDLLKQ 1979



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 50/202 (24%), Positives = 92/202 (45%), Gaps = 7/202 (3%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANL-QMVLQHFQKEE 60
           E   ++ +++  S    LN  + Q +   L+  +Q++  + A    N+ QM   H  KE 
Sbjct: 735 EANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDH--KET 792

Query: 61  KSMYSAELQKQKQLIAEWKKKA---ESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
           K + S+ L++QKQL     KK    E L+ +   LQE LD+   AL     L + ++ K+
Sbjct: 793 KDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKD 852

Query: 118 EQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGK-VDKVLMRNLFISHFHMPKNQRHEVL 176
             +  +K++N   QE L+ ++++    A   + K +D V      +S  +  K    E +
Sbjct: 853 RSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEI 912

Query: 177 RLMGSILGVRREEMEQLFHDNQ 198
           +    I+  + +   QL    Q
Sbjct: 913 KHHQKIIEDQNQSKMQLLQSLQ 934



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 42/152 (27%), Positives = 69/152 (45%), Gaps = 16/152 (10%)

Query: 12   VESLQEQLNVVSKQRDETALLSASQQQVKQYAL-------------SLANLQMVLQHFQK 58
            V+S+QE+  V  ++RD+  +L+  Q+Q++  AL             S   L+ +  H  +
Sbjct: 1532 VKSMQEKTVVFQQERDQ-VMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLE 1590

Query: 59   EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEAD-AALDSASRLTEQLDLKE 117
             E S Y+ E    +   A+ +KK   LE K++S    ++ A   A      L EQL++  
Sbjct: 1591 SEDS-YTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVS 1649

Query: 118  EQIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
            +Q +E   Q    QE +      L NL   LE
Sbjct: 1650 KQRDETALQLSVSQEQVKQYALSLANLQMVLE 1681



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 30/166 (18%), Positives = 76/166 (45%), Gaps = 21/166 (12%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           +++  H   + +E+ +++LN    +++   L++  ++  +Q   +  ++ ++     K++
Sbjct: 465 LDSELHDLRLNLEAKEQELNQSISEKE--TLIAEIEELDRQNQEATKHMILIKDQLSKQQ 522

Query: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLD-------EADAAL---------- 103
               S  + K KQ + + KK+   LE   + + + LD       +++ AL          
Sbjct: 523 NEGDSI-ISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKL 581

Query: 104 -DSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSL 148
            D    L +QL+  +E    ++K+N   +E +   +++L  + N L
Sbjct: 582 EDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNEL 627



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 27/135 (20%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQH----- 55
           +++  H+ SV   + Q++L  +S++  E         ++  Y   +  L+ +LQ      
Sbjct: 229 IDDHQHEMSVLQNAHQQKLTEISRRHRE---------ELSDYEERIEELENLLQQGGSGV 279

Query: 56  FQKEEKSMYSAELQKQKQLI----AEWKKKAESLERKVISLQERLDEADAALDSASRLTE 111
            + +   +Y  E+QK  Q++     E  KK E LE K+  + ++L  A+   D   R   
Sbjct: 280 IETDLSKIY--EMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRR--- 334

Query: 112 QLDLKEEQIEELKKQ 126
               ++EQ+   K+Q
Sbjct: 335 ----EQEQLNVEKRQ 345


>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2
           [Homo sapiens]
          Length = 1235

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 41/153 (26%), Positives = 77/153 (50%), Gaps = 4/153 (2%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANL--QMVLQHFQ- 57
           +E+ +   SV+ ESL    N+V  ++ E  +L+   QQ ++   S+  L  Q   Q+ + 
Sbjct: 242 LEHVNRDLSVKRESLSHHENIVKARKKEHGMLTRQLQQTEKELKSVETLLNQKRPQYIKA 301

Query: 58  KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDS-ASRLTEQLDLK 116
           KE  S +  +L   K+ I + +K+    E  + +L+  L + DAA  S   ++ E++  K
Sbjct: 302 KENTSHHLKKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQIEEEILHK 361

Query: 117 EEQIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
           +  IE    Q +  +E+ + V+KK+  +   LE
Sbjct: 362 KRDIELEASQLDRYKELKEQVRKKVATMTQQLE 394



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 45/184 (24%), Positives = 81/184 (44%), Gaps = 23/184 (12%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQK-- 58
           EN SH          ++L+V  K  +D     S  +  +K     LA+L    + F+K  
Sbjct: 303 ENTSHHL--------KKLDVAKKSIKDSEKQCSKQEDDIKALETELADLDAAWRSFEKQI 354

Query: 59  EEKSMY--------SAELQKQKQLIAEWKKKAESLERKVISLQ--ERLDEADAALDSASR 108
           EE+ ++        +++L + K+L  + +KK  ++ +++  LQ  ++ DE   A +    
Sbjct: 355 EEEILHKKRDIELEASQLDRYKELKEQVRKKVATMTQQLEKLQWEQKTDEERLAFEKRRH 414

Query: 109 LTEQLDLKE--EQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFH 166
              Q +LK+  EQIE+ KK+ E  +E        L       E  VD++      +S F+
Sbjct: 415 GEVQGNLKQIKEQIEDHKKRIEKLEEYTKTCMDCLKEKKQQEETLVDEIEKTKSRMSEFN 474

Query: 167 MPKN 170
              N
Sbjct: 475 EELN 478



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 31/162 (19%), Positives = 73/162 (45%), Gaps = 24/162 (14%)

Query: 58  KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
           +++K+  + +L+  +  + +   K  +L+  +    E +D    A ++  +   +L  K+
Sbjct: 811 EKQKTRLNVQLEYSRSHLKKKLNKINTLKETIQKGSEDIDHLKKAEENCLQTVNELMAKQ 870

Query: 118 EQIEEL---------KKQNEFQQEM---------LDDVQKKLVNLANSLEGKVDKVLMRN 159
           +Q++++         K Q + ++E          +  +QK++V++  SLE K  ++   N
Sbjct: 871 QQLKDIRVTQNSSAEKVQTQIEEERKKFLAVDREVGKLQKEVVSIQTSLEQK--RLEKHN 928

Query: 160 LFISHFHMPKNQRHEVLRLMGSILGVRREEMEQLFHDNQGSV 201
           L +      K Q  E++ L GS+  +   EM       Q ++
Sbjct: 929 LLLD----CKVQDIEIILLSGSLDDIIEVEMGTEAESTQATI 966


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 48.5 bits (114), Expect = 9e-06
 Identities = 45/151 (29%), Positives = 79/151 (52%), Gaps = 15/151 (9%)

Query: 11  QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQK 70
           QV   QEQL    +Q  E  LL   Q+Q++Q  L     Q+  Q FQ++++     +LQ+
Sbjct: 186 QVLQQQEQLQ---QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQE-----QLQQ 237

Query: 71  QKQLI---AEWKKKAESLERKVISLQER-LDEADAALDSASRLTEQLDLKEEQIEELKKQ 126
           Q+QL+    + + + + L+++   LQ++ L++  A L     L +Q  L+++Q ++L +Q
Sbjct: 238 QQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQ 297

Query: 127 NEFQQEMLDDVQKKLVNLANSLEGKVDKVLM 157
              QQE L   Q +   L    E +V+  LM
Sbjct: 298 ---QQEQLQQQQLQPPPLEPEEEEEVELELM 325



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 49/219 (22%), Positives = 97/219 (44%), Gaps = 20/219 (9%)

Query: 7   QASVQVESLQEQLNVVSKQRD---ETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSM 63
           Q   Q E LQ+Q  ++  Q+    +  LL   Q Q++Q  L     Q+  Q   ++++ +
Sbjct: 227 QFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQL 286

Query: 64  YSAELQKQKQLIAEWKKKAESLERKVISLQ-ERLDEADAALDSASRLTEQLDLKEEQIEE 122
              + Q+Q+QL+ + +++ +  + +   L+ E  +E +  L      +EQ    E+Q +E
Sbjct: 287 ---QQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQ--ELEQQRQE 341

Query: 123 LKKQNEFQ-QEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGS 181
           L++Q E + Q+    +Q KL      LE ++++                Q+   L L   
Sbjct: 342 LERQQELERQQEQRQLQLKLQEELQQLEQQLEQQ----------QQQLEQQEVQLELTPV 391

Query: 182 ILGVRREEMEQLFHDNQGSVTRWMTGWLGRGSKSVPNTP 220
            LG +++E++      Q  +   +    G G  +VP  P
Sbjct: 392 ELGAQQQEVQLELTPVQPELQLELVPAAGGGGAAVPGAP 430



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 27/140 (19%), Positives = 69/140 (49%), Gaps = 7/140 (5%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE- 60
           E    Q  +Q++ L++Q     +Q+ +   L   Q  ++       + Q  L   Q+E+ 
Sbjct: 81  ETRPGQRELQLQQLEQQPE--PQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKH 138

Query: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
           +S++  EL+ + QL+ +     + L+ + +  Q+RL +    L +     +Q+  ++EQ+
Sbjct: 139 QSVHHQELKPELQLMHQ----QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQL 194

Query: 121 EELKKQNEFQQEMLDDVQKK 140
           ++  ++ +  Q+  + +Q++
Sbjct: 195 QQQVQEQQLLQQQQEQLQQQ 214



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 29/135 (21%), Positives = 67/135 (49%), Gaps = 16/135 (11%)

Query: 7   QASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA 66
           Q  +Q + +QEQ  +  +Q+++     A +QQV Q    L       Q  Q++++ +   
Sbjct: 156 QQQLQPQQVQEQQRL-QQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ 214

Query: 67  ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQ 126
           +L +Q++ + + + + +         QE+L +    L     L +Q  L+++ +++  +Q
Sbjct: 215 QLLQQQEQLQQQQFQQQ---------QEQLQQQQQLL----LLQQQGQLQQQLLQQ--QQ 259

Query: 127 NEFQQEMLDDVQKKL 141
            + QQ++L+  Q +L
Sbjct: 260 AQLQQQLLEQQQAQL 274



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 30/127 (23%), Positives = 65/127 (51%), Gaps = 10/127 (7%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
           Q+QL+ + +++ +    S   Q++K   L L + Q  LQ  Q +E+      LQ+Q++ +
Sbjct: 127 QQQLSQLQQEKHQ----SVHHQELKP-ELQLMHQQQQLQPQQVQEQQ----RLQQQQEQL 177

Query: 76  AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
              + + + + ++   LQ+++ E         +L +Q  L ++Q +  ++Q + QQE L 
Sbjct: 178 QTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQ-QLLQQQEQLQQQQFQQQQEQLQ 236

Query: 136 DVQKKLV 142
             Q+ L+
Sbjct: 237 QQQQLLL 243


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 49/204 (24%), Positives = 90/204 (44%), Gaps = 32/204 (15%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQ------VKQYALSLANLQMVLQ 54
            +E    +   +VE L   L     +R  TA  +  ++Q      + ++   L   Q  L+
Sbjct: 1418 LEKTKQRLQGEVEDLMRDL-----ERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELE 1472

Query: 55   HFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLD 114
              QKE +S+ S EL K +    E   + E+L R+  +LQE + +          LTEQ+ 
Sbjct: 1473 AAQKESRSL-STELFKMRNAYEEVVDQLETLRRENKNLQEEISD----------LTEQIA 1521

Query: 115  LKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHE 174
               + ++E +K  +  ++   D+Q  L  +  SLE +  K+L   L +S      +++  
Sbjct: 1522 ETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRK-- 1579

Query: 175  VLRLMGSILGVRREEMEQLFHDNQ 198
                    +  + EE+EQL  ++Q
Sbjct: 1580 --------VIEKDEEIEQLKRNSQ 1595



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 37/165 (22%), Positives = 71/165 (43%), Gaps = 17/165 (10%)

Query: 1    MENASHQASVQVE----------SLQEQLNVVSKQRDETALLSASQQ--QVKQYALSLAN 48
            +E AS   S Q+E           ++  L   + Q + TA     +Q   V +    + N
Sbjct: 1154 LEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDN 1213

Query: 49   LQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASR 108
            LQ V Q  +KE KS    E+      I    K   ++ER   +++++  E  A  +  ++
Sbjct: 1214 LQRVKQKLEKE-KSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQ 1272

Query: 109  LTEQLDLKEEQIE----ELKKQNEFQQEMLDDVQKKLVNLANSLE 149
            L   L++++ +++    EL  + E ++ ++  + K    L   LE
Sbjct: 1273 LIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLE 1317



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 36/167 (21%), Positives = 75/167 (44%), Gaps = 14/167 (8%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
            +E+        ++ L+  L  V K++       A++ +VK  +  +  L+  +    KE+
Sbjct: 947  LEDKCSSLKRDIDDLELTLTKVEKEKH------ATENKVKNLSEEMTALEENISKLTKEK 1000

Query: 61   KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
            KS+  A  Q    L  E + K   L +    L+++ D+ + +L+   +L   L+  + ++
Sbjct: 1001 KSLQEAHQQTLDDLQVE-EDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKL 1059

Query: 121  E-ELKKQNEFQQEMLDDVQ------KKLVNLANSLEGKVDKVLMRNL 160
            E +LK   E   ++ +D Q      KK     + L+ K+D   + +L
Sbjct: 1060 EGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSL 1106



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 27/119 (22%), Positives = 62/119 (52%), Gaps = 5/119 (4%)

Query: 11   QVESLQEQLNVVSKQRDETAL-LSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ 69
            Q+++LQ     + K++ E  + +      ++  + S +N++   +  + ++ S   A+ +
Sbjct: 1210 QIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVE-DQFSEIKAKDE 1268

Query: 70   KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNE 128
            +Q QLI +   +   L+ +   L  R++E ++ +   S+LT+      +Q+EELK+Q E
Sbjct: 1269 QQTQLIHDLNMQKARLQTQNGELSHRVEEKESLI---SQLTKSKQALTQQLEELKRQME 1324



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 26/113 (23%), Positives = 57/113 (50%), Gaps = 11/113 (9%)

Query: 29   TALLSASQQQVKQYALSLANLQMVLQHFQKEEK---------SMYSAELQKQKQLIAEWK 79
            T+L++  ++     A   A ++  +Q  +  E+         +M + EL+K++   A  +
Sbjct: 1725 TSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784

Query: 80   KKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
            +  ++LE+ V  LQ RLDEA+       +  +Q+   E ++ EL+ + + +Q+
Sbjct: 1785 RMKKNLEQTVKDLQHRLDEAEQLALKGGK--KQIQKLENRVRELENELDVEQK 1835



 Score = 36.2 bits (82), Expect = 0.045
 Identities = 37/158 (23%), Positives = 65/158 (41%), Gaps = 20/158 (12%)

Query: 2    ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
            E+   Q +   ++L +QL  + +Q +E        +    +AL  +     L   Q EE+
Sbjct: 1299 ESLISQLTKSKQALTQQLEELKRQMEE----ETKAKNAMAHALQSSRHDCDLLREQYEEE 1354

Query: 62   SMYSAELQ----KQKQLIAEWKKK--------AESLERKVISLQERLDEADAALDSASRL 109
                AELQ    K    +A+W+ K         E LE     L +RL EA+   ++A+  
Sbjct: 1355 QEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSK 1414

Query: 110  TEQLDLKEE----QIEELKKQNEFQQEMLDDVQKKLVN 143
               L+  ++    ++E+L +  E        + KK  N
Sbjct: 1415 CASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRN 1452



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 36/171 (21%), Positives = 72/171 (42%), Gaps = 33/171 (19%)

Query: 7    QASVQVESLQEQLNV-------VSKQRDETA--LLSASQQQVKQYALSLANLQMVLQH-- 55
            +   ++E L+E++         + KQR + A  L   S++  +    + A ++M  +   
Sbjct: 1114 ELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREA 1173

Query: 56   -FQKEEKSMYSAELQ----------KQKQLIAEWKKKAESLERKVISLQERLDEADAALD 104
             FQK  + +  A LQ          KQ   +AE  ++ ++L+R    L++   E    +D
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1233

Query: 105  -----------SASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNL 144
                       S S +       E+Q  E+K ++E Q +++ D+  +   L
Sbjct: 1234 DMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARL 1284



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 32/145 (22%), Positives = 67/145 (46%), Gaps = 15/145 (10%)

Query: 36   QQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQER 95
            Q+++      +A     LQ  +K +K +   E    +  + E +   E  E K++ +Q  
Sbjct: 1510 QEEISDLTEQIAETGKNLQEAEKTKK-LVEQEKSDLQVALEEVEGSLEHEESKILRVQLE 1568

Query: 96   LDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDV-------QKKLVNLANSL 148
            L +  + LD       ++  K+E+IE+LK+ ++   E L  V       +   + L   +
Sbjct: 1569 LSQVKSELD------RKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKM 1622

Query: 149  EGKVDKVLMRNLFISHFHMPKNQRH 173
            EG ++++ ++ L  S+  M + Q+H
Sbjct: 1623 EGDLNEMEIQ-LGHSNRQMAETQKH 1646



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 29/137 (21%), Positives = 60/137 (43%), Gaps = 12/137 (8%)

Query: 13   ESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQK 72
            E L+EQL +V ++     LL    +++K  AL        L   +  + S     L  Q 
Sbjct: 1669 EDLKEQLAIVERRN---GLLLEELEEMK-VALEQTERTRRLSEQELLDASDRVQLLHSQN 1724

Query: 73   QLIAEWKKKAES--------LERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELK 124
              +   KKK E+        +E  +   +   ++A  A+  A+ + E+L  +++    L+
Sbjct: 1725 TSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE 1784

Query: 125  KQNEFQQEMLDDVQKKL 141
            +  +  ++ + D+Q +L
Sbjct: 1785 RMKKNLEQTVKDLQHRL 1801


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 43/196 (21%), Positives = 87/196 (44%), Gaps = 41/196 (20%)

Query: 12   VESLQEQLNVVSKQRD-----------------ETALLSASQQQVKQYALSLANLQMVLQ 54
            VE L+ QL +  KQ+                  E  ++SA+ Q+         N+Q ++ 
Sbjct: 1727 VERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHL-----NVQQIVD 1781

Query: 55   HFQKEEKSMY---SAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTE 111
               +E K+     +  L K K+ +   K +  SL   +  L   L +   A +   R  E
Sbjct: 1782 RHTRELKTQVEDLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKE 1841

Query: 112  QLDLKEEQIEELKKQ----------NEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLF 161
            ++D + ++++   K+           + +Q +++++Q+K+  L N LEGKV++V ++ + 
Sbjct: 1842 EIDQENDELKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLEGKVEEVDLKPM- 1900

Query: 162  ISHFHMPKNQRHEVLR 177
                   KN + E++R
Sbjct: 1901 -----KEKNAKEELIR 1911



 Score = 32.0 bits (71), Expect = 0.86
 Identities = 30/168 (17%), Positives = 81/168 (48%), Gaps = 20/168 (11%)

Query: 8   ASVQVESL--QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYS 65
           + V+V  L  ++Q NV+   R   +L+    Q+V+   L+L  ++   +   K E  + +
Sbjct: 33  SKVEVNELKSEKQENVIHLFRITQSLMKMKAQEVE---LALEEVEKAGEEQAKFENQLKT 89

Query: 66  AELQKQKQLIAEWK----KKAESLERKVISLQERLDEADAALDSASR-------LTEQLD 114
             ++ + +L    +    +    L  ++  L+++L++ D  L+   +       + EQL 
Sbjct: 90  KVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQLEQKDRELEDMEKELEKEKKVNEQLA 149

Query: 115 LKEEQIE----ELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMR 158
           L+ E+ E    +L+++N+  ++  + + + +++    ++ + + +L R
Sbjct: 150 LRNEEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLSR 197



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 50/254 (19%), Positives = 103/254 (40%), Gaps = 37/254 (14%)

Query: 2    ENASHQASVQVESLQEQLN--VVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE 59
            E A + A ++  +  + L   + S +R  +  L  +QQ+  +++ ++  LQ         
Sbjct: 1246 EQALYYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQE--KFSKTMIQLQ--------N 1295

Query: 60   EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
            +K     E++  +Q     + K   +E K+  L+E +        +   +   + ++E +
Sbjct: 1296 DKLKIMQEMKNSQQEHRNMENKTLEMELKLKGLEELISTLKDTKGAQKVINWHMKIEELR 1355

Query: 120  IEELKKQNEFQQE-----MLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHE 174
            ++ELK   E  ++      L+++  +     +SLE   ++++ +N F     M  +QR  
Sbjct: 1356 LQELKLNRELVKDKEEIKYLNNIISEYERTISSLE---EEIVQQNKFHEERQMAWDQREV 1412

Query: 175  VLRLMGSILGVRREEM---EQLFHDNQGSVTRWMTGWLGRGSKSVPNTPLRPNQQSVLNS 231
             L     I   ++ E+    Q F +  GS+               P+ PL PNQ  +   
Sbjct: 1413 DLERQLDIFDRQQNEILNAAQKFEEATGSIPD-------------PSLPL-PNQLEIALR 1458

Query: 232  SFSECFVKFLETES 245
               E     LET +
Sbjct: 1459 KIKENIRIILETRA 1472



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 35/157 (22%), Positives = 71/157 (45%), Gaps = 20/157 (12%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQ----YALSLANLQMVLQHFQKEEKSMYSAELQKQ 71
           +E  N  SK R E   L    +Q+ Q    Y   + + +  L   ++ E S Y ++L K+
Sbjct: 153 EEAENENSKLRRENKRLKKKNEQLCQDIIDYQKQIDSQKETLLS-RRGEDSDYRSQLSKK 211

Query: 72  K----------QLIAEWKKKAESLERKVI-SLQERLDEADAALDSASRLTEQLDLKEEQI 120
                      Q + E  +K E   +++  +L+E + E +   D  +R+   +   +  I
Sbjct: 212 NYELIQYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVI 271

Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLM 157
           ++LKK+N+  Q  +    ++L +L  S   + D +++
Sbjct: 272 DQLKKENDHYQLQV----QELTDLLKSKNEEDDPIMV 304



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 48/196 (24%), Positives = 86/196 (43%), Gaps = 22/196 (11%)

Query: 12   VESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQM-----VLQHFQKEEKSMYSA 66
            + SL+E++   +K  +E  +    ++   +  L + + Q        Q F++   S+   
Sbjct: 1386 ISSLEEEIVQQNKFHEERQMAWDQREVDLERQLDIFDRQQNEILNAAQKFEEATGSIPDP 1445

Query: 67   ELQKQKQLIAEWKKKAES----LERKVI--SLQERLDEADAALDSASRLTEQLDLKEEQ- 119
             L    QL    +K  E+    LE +    SL+E+L E ++AL    RL EQ  L  ++ 
Sbjct: 1446 SLPLPNQLEIALRKIKENIRIILETRATCKSLEEKLKEKESAL----RLAEQNILSRDKV 1501

Query: 120  IEELKKQNEFQQEMLDDVQKKLVNLANS-LEGKVDKVL-MRNLFISHFHMPKNQRHEVLR 177
            I EL+ +     E     +K +  L    +E K    L + +  I++     NQ+ EVL+
Sbjct: 1502 INELRLRLPATAER----EKLIAELGRKEMEPKSHHTLKIAHQTIANMQARLNQKEEVLK 1557

Query: 178  LMGSILGVRREEMEQL 193
                +L   REE  ++
Sbjct: 1558 KYQRLLEKAREEQREI 1573



 Score = 28.5 bits (62), Expect = 9.5
 Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 23/151 (15%)

Query: 7   QASVQVESLQEQLNVVSKQRDETALLSAS---QQQVKQYALSLANLQMVLQHFQKEEKSM 63
           + S+ + SL+  +N +  +  E  +  AS   + QV Q       L+  L+  +KE  + 
Sbjct: 671 ETSLIIPSLERLVNAIESKNAE-GIFDASLHLKAQVDQLTGRNEELRQELRESRKEAIN- 728

Query: 64  YSAELQKQKQLIAEWKKKAESLERKVIS--LQERLDEADAALDSASRLTEQLDLKEEQIE 121
           YS +L K    I   +K+   L +   S  + + +D  D    S++ +            
Sbjct: 729 YSQQLAKANLKIDHLEKETSLLRQSEGSNVVFKGIDLPDGIAPSSASI------------ 776

Query: 122 ELKKQNEFQQEMLDDVQ---KKLVNLANSLE 149
            +  QNE+   +L +++   KKL NL +SLE
Sbjct: 777 -INSQNEYLIHLLQELENKEKKLKNLEDSLE 806



 Score = 28.5 bits (62), Expect = 9.5
 Identities = 29/121 (23%), Positives = 60/121 (49%), Gaps = 7/121 (5%)

Query: 80   KKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQK 139
            ++ + L+++ + L     E    L+ A++   +L   + Q+ +LK+  EF ++   +VQ+
Sbjct: 2056 QREQELQKENLKLSSENIELKFQLEQANKDLPRL---KNQVRDLKEMCEFLKKEKAEVQR 2112

Query: 140  KLVNLANS-LEGKVDKVLMRNLFISHFHMPKNQR-HEVLRLMGSILGVRREEMEQLFHDN 197
            KL ++  S   GK    L + + +    + K QR +E L+    IL    E+M  +  +N
Sbjct: 2113 KLGHVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGIL--TSEKMANIEQEN 2170

Query: 198  Q 198
            +
Sbjct: 2171 E 2171


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 54/272 (19%), Positives = 130/272 (47%), Gaps = 40/272 (14%)

Query: 12   VESLQEQLNVVSKQRDETALLSASQQQVKQYALSLA-NLQMVLQHFQKEEKSMYSAELQK 70
            +E  ++  +++ ++ +   +L +   + +Q    L  N++M +++  +EE  +   EL+K
Sbjct: 1039 IEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIEN--QEELRLLGDELKK 1096

Query: 71   QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQ 130
            Q++++A+ K  A   E ++    +RL E +          E+L  K +Q++E ++Q    
Sbjct: 1097 QQEIVAQEKNHAIKKEGELSRTCDRLAEVE----------EKLKEKSQQLQEKQQQLLNV 1146

Query: 131  QEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPK-------NQRHEVLRLMGSIL 183
            QE + ++QKK+    N +E   +++  + L + H    +       N+ +E ++   SI 
Sbjct: 1147 QEEMSEMQKKI----NEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVK---SIT 1199

Query: 184  GVRR--EEMEQLFHDNQGSVTRWM-----TGWLGRGSKSVPNTPLRPNQQSV--LNSSFS 234
              R+  +E+++ F   +  +  ++     TG   +    + +  L+ +Q+++  L  S S
Sbjct: 1200 KERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVS 1259

Query: 235  ECFVKFLETE----SHSSVPPPKLSVHDMKPL 262
            E   + + T+    SH+ +      +H+ + L
Sbjct: 1260 EKTAQIINTQDLEKSHTKLQEEIPVLHEEQEL 1291



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 35/182 (19%), Positives = 79/182 (43%), Gaps = 18/182 (9%)

Query: 15  LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQL 74
           +Q  L  + K +D+   L+ +Q   K       N + +   F+++ K M   E ++  Q 
Sbjct: 791 VQGLLEEIGKTKDD---LATTQSNYKSTDQEFQNFKTLHMDFEQKYK-MVLEENERMNQE 846

Query: 75  IAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEML 134
           I    K+A+  +  + +L+  L      L   +R  ++   +  ++E+LK+Q E +   L
Sbjct: 847 IVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQE---RLNEMEQLKEQLENRDSTL 903

Query: 135 DDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSILGVRREEMEQLF 194
             V+++   +   L+  +++V               Q  + L+ +   L + R++++   
Sbjct: 904 QTVEREKTLITEKLQQTLEEV-----------KTLTQEKDDLKQLQESLQIERDQLKSDI 952

Query: 195 HD 196
           HD
Sbjct: 953 HD 954



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 34/167 (20%), Positives = 74/167 (44%), Gaps = 16/167 (9%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQY-----ALSLANLQMVLQH 55
           ++N    A V  + L+ +L+       +  LL   + Q+K+      +  L N++M L +
Sbjct: 559 LKNLVKHAEVYNQDLENELS------SKVELLREKEDQIKKLQEYIDSQKLENIKMDLSY 612

Query: 56  FQK--EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQL 113
             +  E+       L   + +  + K+++  L  + + L+E++ E         ++   +
Sbjct: 613 SLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTY---KQMENDI 669

Query: 114 DLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNL 160
            L + Q+E  KK     ++ L     ++  L + ++GKV K L+ NL
Sbjct: 670 QLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNL 716



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 34/159 (21%), Positives = 64/159 (40%), Gaps = 8/159 (5%)

Query: 2    ENASHQASVQVE--SLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE 59
            EN     SV  E  +L+     +  +RD+   L  S Q+ K   L +       +   KE
Sbjct: 1879 ENLEEMKSVMKERDNLRRVEETLKLERDQ---LKESLQETKARDLEIQQELKTARMLSKE 1935

Query: 60   EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
             K       +K  +   +     + L++    LQ+++ E         R+ E +++  ++
Sbjct: 1936 HKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKK 1995

Query: 120  I---EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
            I   E+LKKQ E Q   +  V+     L   L   ++++
Sbjct: 1996 INEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEI 2034



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 37/167 (22%), Positives = 77/167 (46%), Gaps = 29/167 (17%)

Query: 16   QEQLNVVS---KQRDETALLSASQQQVKQYALSLANLQMVLQHFQ----------KEEKS 62
            QE+L +V    K+  ET  +   +  V +    ++N+Q  L+H            +EE  
Sbjct: 1720 QEELKIVHMHLKEHQET--IDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELR 1777

Query: 63   MYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASR---------LTEQL 113
            +    L++Q++ I + +        K+ ++Q+ L+ ++A L    +         +T + 
Sbjct: 1778 IAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKK 1837

Query: 114  DLKEEQ-----IEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
            D+ E Q     +E+LKKQ + Q   L  ++ + +NLA  L   ++++
Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEM 1884



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 48/233 (20%), Positives = 108/233 (46%), Gaps = 47/233 (20%)

Query: 15   LQEQLNVVSKQR----DETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYS--AEL 68
            L+EQ   +++ R    ++   +S  Q+Q++     L N   + + ++KEE+      +E+
Sbjct: 1486 LKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQN--KIQEIYEKEEQFNIKQISEV 1543

Query: 69   QKQKQLIAEWK--KKA-----ESLERKVISLQERLDEADAAL-------DSASRLTEQLD 114
            Q++   + ++K  +KA     +S+E K++ L  RL E+   +       +   R+ E L 
Sbjct: 1544 QEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQ 1603

Query: 115  LKEEQIEE--------LKKQNEFQQEML-----DDVQKKLVNLANSLEG-KVDKVLMRNL 160
            ++ +Q++E        +K+  E + + L     ++ Q+K+  + +  E  +  K+ + N+
Sbjct: 1604 IERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENI 1663

Query: 161  FISHFHMPKNQRHEVLRLMGSILGVR----------REEMEQLFHDNQGSVTR 203
               +  + +   HE L  M S+   R          + E +QL  + + ++TR
Sbjct: 1664 ETENIRLTQ-ILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITR 1715


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
           sapiens]
          Length = 1293

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 27/125 (21%), Positives = 68/125 (54%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
           ++Q   + +QR++   L   +++ ++     A  ++  +  ++EE+      L+KQ++  
Sbjct: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841

Query: 76  AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
           A+W ++ E  +R++   + R++E  A L       ++ +L+ ++ +EL +Q + QQE L 
Sbjct: 842 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 901

Query: 136 DVQKK 140
            +Q++
Sbjct: 902 RLQQQ 906



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 26/134 (19%), Positives = 64/134 (47%), Gaps = 16/134 (11%)

Query: 15   LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE-------EKSMYSAE 67
            +Q Q  ++ +++ +   L   QQQ +Q  L+   L       Q+        + ++  AE
Sbjct: 883  VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 942

Query: 68   LQK-----QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLT----EQLDLKEE 118
            +QK     ++QL  E +++   L + +   Q++  +  +   + S+ +      L++++E
Sbjct: 943  IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1002

Query: 119  QIEELKKQNEFQQE 132
            +  +++KQ + QQ+
Sbjct: 1003 EARQMQKQQQQQQQ 1016


>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
           sapiens]
          Length = 1320

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 27/125 (21%), Positives = 68/125 (54%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
           ++Q   + +QR++   L   +++ ++     A  ++  +  ++EE+      L+KQ++  
Sbjct: 809 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 868

Query: 76  AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
           A+W ++ E  +R++   + R++E  A L       ++ +L+ ++ +EL +Q + QQE L 
Sbjct: 869 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 928

Query: 136 DVQKK 140
            +Q++
Sbjct: 929 RLQQQ 933



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 26/134 (19%), Positives = 64/134 (47%), Gaps = 16/134 (11%)

Query: 15   LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE-------EKSMYSAE 67
            +Q Q  ++ +++ +   L   QQQ +Q  L+   L       Q+        + ++  AE
Sbjct: 910  VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 969

Query: 68   LQK-----QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLT----EQLDLKEE 118
            +QK     ++QL  E +++   L + +   Q++  +  +   + S+ +      L++++E
Sbjct: 970  IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1029

Query: 119  QIEELKKQNEFQQE 132
            +  +++KQ + QQ+
Sbjct: 1030 EARQMQKQQQQQQQ 1043


>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 27/125 (21%), Positives = 68/125 (54%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
           ++Q   + +QR++   L   +++ ++     A  ++  +  ++EE+      L+KQ++  
Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847

Query: 76  AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
           A+W ++ E  +R++   + R++E  A L       ++ +L+ ++ +EL +Q + QQE L 
Sbjct: 848 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 907

Query: 136 DVQKK 140
            +Q++
Sbjct: 908 RLQQQ 912



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 26/134 (19%), Positives = 64/134 (47%), Gaps = 16/134 (11%)

Query: 15   LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE-------EKSMYSAE 67
            +Q Q  ++ +++ +   L   QQQ +Q  L+   L       Q+        + ++  AE
Sbjct: 889  VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 948

Query: 68   LQK-----QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLT----EQLDLKEE 118
            +QK     ++QL  E +++   L + +   Q++  +  +   + S+ +      L++++E
Sbjct: 949  IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008

Query: 119  QIEELKKQNEFQQE 132
            +  +++KQ + QQ+
Sbjct: 1009 EARQMQKQQQQQQQ 1022


>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
           sapiens]
          Length = 1299

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 27/125 (21%), Positives = 68/125 (54%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
           ++Q   + +QR++   L   +++ ++     A  ++  +  ++EE+      L+KQ++  
Sbjct: 788 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 847

Query: 76  AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLD 135
           A+W ++ E  +R++   + R++E  A L       ++ +L+ ++ +EL +Q + QQE L 
Sbjct: 848 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALR 907

Query: 136 DVQKK 140
            +Q++
Sbjct: 908 RLQQQ 912



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 26/134 (19%), Positives = 64/134 (47%), Gaps = 16/134 (11%)

Query: 15   LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE-------EKSMYSAE 67
            +Q Q  ++ +++ +   L   QQQ +Q  L+   L       Q+        + ++  AE
Sbjct: 889  VQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE 948

Query: 68   LQK-----QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLT----EQLDLKEE 118
            +QK     ++QL  E +++   L + +   Q++  +  +   + S+ +      L++++E
Sbjct: 949  IQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE 1008

Query: 119  QIEELKKQNEFQQE 132
            +  +++KQ + QQ+
Sbjct: 1009 EARQMQKQQQQQQQ 1022


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 37/153 (24%), Positives = 75/153 (49%), Gaps = 9/153 (5%)

Query: 5    SHQASVQVESLQEQLNVVSKQRDETALLSAS---QQQVKQYALSLANLQMVLQHFQKEEK 61
            S  +    E+ +E+L     QR++  LL+ +   +QQ+++  + +A     +   + E +
Sbjct: 1465 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524

Query: 62   SMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI- 120
             + S E  K +  +A+ KK+   LE KV   +E LDE    +    +   +L+++ E++ 
Sbjct: 1525 DISSQE-SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMR 1583

Query: 121  ----EELKKQNEFQQEMLDDVQKKLVNLANSLE 149
                +E++ ++E  +E     QKKL  +   LE
Sbjct: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 4/104 (3%)

Query: 55   HFQKEEKSMYSAELQKQKQLIAEWKKKAES-LERKVISLQERLDEADAALDSASRLTEQL 113
            H Q ++ +     L++Q   +   K + ++ LE     + E + +  AA+  ASR   Q+
Sbjct: 1717 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1776

Query: 114  DLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLM 157
            +  + Q+EE  K+ +  QE L  +Q ++  L  S+   VDK L+
Sbjct: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM---VDKSLV 1817



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 38/173 (21%), Positives = 78/173 (45%), Gaps = 18/173 (10%)

Query: 5    SHQASVQVESLQEQ-----LNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQK 58
            S +A +Q  S QE      L  V KQ RD  A +   ++++ + A ++  L+      + 
Sbjct: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577

Query: 59   EEKSM---YSAELQKQKQLIAEWKKKAES-LERKVISLQERLDEADAALDSASRLTEQLD 114
            E + M   +S E++ + + + E ++  +  L++  + L+E  ++    L     L  +L 
Sbjct: 1578 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637

Query: 115  LKEEQI--------EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRN 159
               +Q+        + L+K  +  + +L D Q  L +L NS   K +   ++N
Sbjct: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 33/163 (20%), Positives = 76/163 (46%), Gaps = 17/163 (10%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQV----KQYALSLANLQMVLQHF 56
            ME+   +     +S Q++L  +  Q +E       +Q+V    ++    LA L   +   
Sbjct: 1590 MESRDEEVEEARQSCQKKLKQMEVQLEEEY---EDKQKVLREKRELEGKLATLSDQVNRR 1646

Query: 57   QKEEKSMYSAELQKQKQLIAEWK------KKAESLERKVISLQERLDEADAALDSASRLT 110
              E +     +L++ K L+A+ +      K +   +R++  L+ +L+E++    +A +  
Sbjct: 1647 DFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKAR 1706

Query: 111  EQLDLKEE----QIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
            + ++++ E    QI+++ K     +E L  +Q++   + N LE
Sbjct: 1707 KAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLE 1749



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 20/136 (14%)

Query: 11   QVESLQEQLNVVSKQRDETA-LLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ 69
            Q+  LQ QL   +K++ E    L A Q QV+    S+             +KS+ S +  
Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV------------DKSLVSRQEA 1822

Query: 70   KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEF 129
            K ++L    + +   ++R + SL  RL E      +  +LTE+ D +       K+QN+ 
Sbjct: 1823 KIRELETRLEFERTQVKR-LESLASRLKE------NMEKLTEERDQRIAAENREKEQNKR 1875

Query: 130  QQEMLDDVQKKLVNLA 145
             Q  L D ++++  LA
Sbjct: 1876 LQRQLRDTKEEMGELA 1891



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 26/149 (17%), Positives = 77/149 (51%), Gaps = 9/149 (6%)

Query: 11   QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQ----KEEKSMYSA 66
            ++++LQ Q+  + +   + +L+S  + ++++    L   +  ++  +    + +++M   
Sbjct: 1796 KLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKL 1855

Query: 67   ELQKQKQLIAEWKKKAES--LERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELK 124
              ++ +++ AE ++K ++  L+R++   +E + E       ASR   +L++    +E L+
Sbjct: 1856 TEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM---DLESLE 1912

Query: 125  KQNEFQQEMLDDVQKKLVNLANSLEGKVD 153
              N+  Q  L    K++ +L  ++E +++
Sbjct: 1913 AANQSLQADLKLAFKRIGDLQAAIEDEME 1941



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 14/106 (13%)

Query: 59   EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERL-------DEADAALD--SASRL 109
            EE     ++L+K ++   E +  ++ LE ++  L   L       + A   LD  +A RL
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320

Query: 110  TEQLDLKE--EQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVD 153
              + ++KE   Q + LKKQ E  +  ++ ++ +L+  A  + G+VD
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVME--MEVMEARLIRAA-EINGEVD 1363


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 37/153 (24%), Positives = 75/153 (49%), Gaps = 9/153 (5%)

Query: 5    SHQASVQVESLQEQLNVVSKQRDETALLSAS---QQQVKQYALSLANLQMVLQHFQKEEK 61
            S  +    E+ +E+L     QR++  LL+ +   +QQ+++  + +A     +   + E +
Sbjct: 1465 SELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524

Query: 62   SMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI- 120
             + S E  K +  +A+ KK+   LE KV   +E LDE    +    +   +L+++ E++ 
Sbjct: 1525 DISSQE-SKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMR 1583

Query: 121  ----EELKKQNEFQQEMLDDVQKKLVNLANSLE 149
                +E++ ++E  +E     QKKL  +   LE
Sbjct: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 28/104 (26%), Positives = 52/104 (50%), Gaps = 4/104 (3%)

Query: 55   HFQKEEKSMYSAELQKQKQLIAEWKKKAES-LERKVISLQERLDEADAALDSASRLTEQL 113
            H Q ++ +     L++Q   +   K + ++ LE     + E + +  AA+  ASR   Q+
Sbjct: 1717 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1776

Query: 114  DLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLM 157
            +  + Q+EE  K+ +  QE L  +Q ++  L  S+   VDK L+
Sbjct: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM---VDKSLV 1817



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 38/173 (21%), Positives = 78/173 (45%), Gaps = 18/173 (10%)

Query: 5    SHQASVQVESLQEQ-----LNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQK 58
            S +A +Q  S QE      L  V KQ RD  A +   ++++ + A ++  L+      + 
Sbjct: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577

Query: 59   EEKSM---YSAELQKQKQLIAEWKKKAES-LERKVISLQERLDEADAALDSASRLTEQLD 114
            E + M   +S E++ + + + E ++  +  L++  + L+E  ++    L     L  +L 
Sbjct: 1578 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637

Query: 115  LKEEQI--------EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRN 159
               +Q+        + L+K  +  + +L D Q  L +L NS   K +   ++N
Sbjct: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 33/163 (20%), Positives = 76/163 (46%), Gaps = 17/163 (10%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQV----KQYALSLANLQMVLQHF 56
            ME+   +     +S Q++L  +  Q +E       +Q+V    ++    LA L   +   
Sbjct: 1590 MESRDEEVEEARQSCQKKLKQMEVQLEEEY---EDKQKVLREKRELEGKLATLSDQVNRR 1646

Query: 57   QKEEKSMYSAELQKQKQLIAEWK------KKAESLERKVISLQERLDEADAALDSASRLT 110
              E +     +L++ K L+A+ +      K +   +R++  L+ +L+E++    +A +  
Sbjct: 1647 DFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKAR 1706

Query: 111  EQLDLKEE----QIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
            + ++++ E    QI+++ K     +E L  +Q++   + N LE
Sbjct: 1707 KAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLE 1749



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 36/136 (26%), Positives = 62/136 (45%), Gaps = 20/136 (14%)

Query: 11   QVESLQEQLNVVSKQRDETA-LLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ 69
            Q+  LQ QL   +K++ E    L A Q QV+    S+             +KS+ S +  
Sbjct: 1775 QINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV------------DKSLVSRQEA 1822

Query: 70   KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEF 129
            K ++L    + +   ++R + SL  RL E      +  +LTE+ D +       K+QN+ 
Sbjct: 1823 KIRELETRLEFERTQVKR-LESLASRLKE------NMEKLTEERDQRIAAENREKEQNKR 1875

Query: 130  QQEMLDDVQKKLVNLA 145
             Q  L D ++++  LA
Sbjct: 1876 LQRQLRDTKEEMGELA 1891



 Score = 32.7 bits (73), Expect = 0.50
 Identities = 34/202 (16%), Positives = 93/202 (46%), Gaps = 15/202 (7%)

Query: 11   QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQ----KEEKSMYSA 66
            ++++LQ Q+  + +   + +L+S  + ++++    L   +  ++  +    + +++M   
Sbjct: 1796 KLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKL 1855

Query: 67   ELQKQKQLIAEWKKKAES--LERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELK 124
              ++ +++ AE ++K ++  L+R++   +E + E       ASR   +L++    +E L+
Sbjct: 1856 TEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM---DLESLE 1912

Query: 125  KQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSILG 184
              N+  Q  L    K++ +L  ++E +++     +L  S   M    +    +L G    
Sbjct: 1913 AANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGD--- 1969

Query: 185  VRREEMEQLFHDNQGSVTRWMT 206
                +++    D    V  W++
Sbjct: 1970 ---SDVDSELEDRVDGVKSWLS 1988



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 28/106 (26%), Positives = 53/106 (50%), Gaps = 14/106 (13%)

Query: 59   EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERL-------DEADAALD--SASRL 109
            EE     ++L+K ++   E +  ++ LE ++  L   L       + A   LD  +A RL
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320

Query: 110  TEQLDLKE--EQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVD 153
              + ++KE   Q + LKKQ E  +  ++ ++ +L+  A  + G+VD
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVME--MEVMEARLIRAA-EINGEVD 1363


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 42/157 (26%), Positives = 87/157 (55%), Gaps = 26/157 (16%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
           EN S  + V+ E+L+++L ++ ++  E +  + S Q+  Q  ++         H ++E+ 
Sbjct: 791 ENLSEVSQVK-ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKL-------HQKEEQF 842

Query: 62  SMYSAELQKQKQLIAEWKKK---AESLERKVISLQERLDEADAAL-----DSASRLT--- 110
           +M S++L+K ++ +A+ + K    +  E ++I  +E+L+   A +     D++S+LT   
Sbjct: 843 NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMN 902

Query: 111 EQLDLKEEQIEELK----KQNE---FQQEMLDDVQKK 140
           ++L LKE  +EEL+    K NE   F Q+ ++D+  K
Sbjct: 903 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 939



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 26/148 (17%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQ--------RDETALLSASQQQVKQYALSLANLQMV 52
           +  AS +   +++ L++QL    KQ          E++  S+  ++++   L L NLQ  
Sbjct: 733 LRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN 792

Query: 53  LQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQ 112
           L    + ++++   ELQ  K+  AE  ++A S++R   S+QE +++              
Sbjct: 793 LSEVSQVKETL-EKELQILKEKFAEASEEAVSVQR---SMQETVNK-------------- 834

Query: 113 LDLKEEQIEELKKQNEFQQEMLDDVQKK 140
           L  KEEQ   L    E  +E L D++ K
Sbjct: 835 LHQKEEQFNMLSSDLEKLRENLADMEAK 862



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 36/174 (20%), Positives = 81/174 (46%), Gaps = 15/174 (8%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQRDET--ALLSASQQQVKQYALSLANLQMVLQH--FQ 57
           E A+H  + ++E+L+ +L  V K+++ +  A+ S   +   Q+ + + +    LQ    +
Sbjct: 638 ERAAH--AKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIK 695

Query: 58  KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
            +E  +  A+  +Q ++I  +  + ++ E K++ L      +        +L +QL+  E
Sbjct: 696 VKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAE 755

Query: 118 EQIEELKKQNEFQQEMLDDVQK-------KLVNLANSLE--GKVDKVLMRNLFI 162
           +QI+ L+ +   +      + +       KL NL  +L    +V + L + L I
Sbjct: 756 KQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 809



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 35/158 (22%), Positives = 66/158 (41%), Gaps = 3/158 (1%)

Query: 36   QQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQER 95
            +Q  K  A   A   M +     +EK+   A L+  KQ  A+ + + ++L+   +   E 
Sbjct: 1031 KQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 1090

Query: 96   LDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
            L+++   L   ++  E+     ++IE LK+    + + L  +Q++ V LA  L    D+V
Sbjct: 1091 LNKSKELLTVENQKMEEF---RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV 1147

Query: 156  LMRNLFISHFHMPKNQRHEVLRLMGSILGVRREEMEQL 193
                       +  NQ  E+ +     +    EE   L
Sbjct: 1148 TSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1185



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 22/138 (15%), Positives = 67/138 (48%), Gaps = 6/138 (4%)

Query: 9    SVQVESLQEQLNVVSKQRDETAL-LSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAE 67
            S Q+  + ++L +  +  +E  L L+ + +       S+ ++ +  +  Q+E    +  E
Sbjct: 895  SSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 954

Query: 68   LQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL-----DSASRLTEQLDLKEEQIEE 122
             ++ ++ +++ +KK E+   +   L+ R + A +       +    L + L   E++++ 
Sbjct: 955  KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 1014

Query: 123  LKKQNEFQQEMLDDVQKK 140
             +++N    + L++++K+
Sbjct: 1015 AREENSGLLQELEELRKQ 1032


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 42/157 (26%), Positives = 87/157 (55%), Gaps = 26/157 (16%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
           EN S  + V+ E+L+++L ++ ++  E +  + S Q+  Q  ++         H ++E+ 
Sbjct: 826 ENLSEVSQVK-ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKL-------HQKEEQF 877

Query: 62  SMYSAELQKQKQLIAEWKKK---AESLERKVISLQERLDEADAAL-----DSASRLT--- 110
           +M S++L+K ++ +A+ + K    +  E ++I  +E+L+   A +     D++S+LT   
Sbjct: 878 NMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMN 937

Query: 111 EQLDLKEEQIEELK----KQNE---FQQEMLDDVQKK 140
           ++L LKE  +EEL+    K NE   F Q+ ++D+  K
Sbjct: 938 DELRLKERDVEELQLKLTKANENASFLQKSIEDMTVK 974



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 38/148 (25%), Positives = 69/148 (46%), Gaps = 26/148 (17%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQ--------RDETALLSASQQQVKQYALSLANLQMV 52
           +  AS +   +++ L++QL    KQ          E++  S+  ++++   L L NLQ  
Sbjct: 768 LRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN 827

Query: 53  LQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQ 112
           L    + ++++   ELQ  K+  AE  ++A S++R   S+QE +++              
Sbjct: 828 LSEVSQVKETL-EKELQILKEKFAEASEEAVSVQR---SMQETVNK-------------- 869

Query: 113 LDLKEEQIEELKKQNEFQQEMLDDVQKK 140
           L  KEEQ   L    E  +E L D++ K
Sbjct: 870 LHQKEEQFNMLSSDLEKLRENLADMEAK 897



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 36/174 (20%), Positives = 81/174 (46%), Gaps = 15/174 (8%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQRDET--ALLSASQQQVKQYALSLANLQMVLQH--FQ 57
           E A+H  + ++E+L+ +L  V K+++ +  A+ S   +   Q+ + + +    LQ    +
Sbjct: 673 ERAAH--AKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIK 730

Query: 58  KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
            +E  +  A+  +Q ++I  +  + ++ E K++ L      +        +L +QL+  E
Sbjct: 731 VKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAE 790

Query: 118 EQIEELKKQNEFQQEMLDDVQK-------KLVNLANSLE--GKVDKVLMRNLFI 162
           +QI+ L+ +   +      + +       KL NL  +L    +V + L + L I
Sbjct: 791 KQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 844



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 35/158 (22%), Positives = 66/158 (41%), Gaps = 3/158 (1%)

Query: 36   QQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQER 95
            +Q  K  A   A   M +     +EK+   A L+  KQ  A+ + + ++L+   +   E 
Sbjct: 1066 KQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEE 1125

Query: 96   LDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
            L+++   L   ++  E+     ++IE LK+    + + L  +Q++ V LA  L    D+V
Sbjct: 1126 LNKSKELLTVENQKMEEF---RKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEV 1182

Query: 156  LMRNLFISHFHMPKNQRHEVLRLMGSILGVRREEMEQL 193
                       +  NQ  E+ +     +    EE   L
Sbjct: 1183 TSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASL 1220



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 22/138 (15%), Positives = 67/138 (48%), Gaps = 6/138 (4%)

Query: 9    SVQVESLQEQLNVVSKQRDETAL-LSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAE 67
            S Q+  + ++L +  +  +E  L L+ + +       S+ ++ +  +  Q+E    +  E
Sbjct: 930  SSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEE 989

Query: 68   LQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL-----DSASRLTEQLDLKEEQIEE 122
             ++ ++ +++ +KK E+   +   L+ R + A +       +    L + L   E++++ 
Sbjct: 990  KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 1049

Query: 123  LKKQNEFQQEMLDDVQKK 140
             +++N    + L++++K+
Sbjct: 1050 AREENSGLLQELEELRKQ 1067


>gi|4504063 golgin 97 [Homo sapiens]
          Length = 767

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 39/168 (23%), Positives = 79/168 (47%), Gaps = 20/168 (11%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQ----VKQYAL----SLANLQMV 52
           +E   +  + Q++ ++ Q   + ++RDE   L   QQQ    +K   L    SL  ++  
Sbjct: 142 LEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQE 201

Query: 53  LQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQ 112
           L+  +  E S    EL    Q+ ++  +K E L+R   +L+E+ D   A+   A      
Sbjct: 202 LEA-RTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITA 260

Query: 113 LDLKEEQIEELKKQ-----------NEFQQEMLDDVQKKLVNLANSLE 149
           L+ KE++++ L +Q            + +++++  +Q+K+ +L   LE
Sbjct: 261 LEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLE 308



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 42/197 (21%), Positives = 87/197 (44%), Gaps = 26/197 (13%)

Query: 5   SHQASVQVESLQEQLNVVSKQRDET-ALLSASQQQVKQYALSLANLQMVLQHFQKEEKSM 63
           S   S ++E LQ   + + +QRD   A  + ++ ++         LQ ++Q    + + +
Sbjct: 223 SSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKV 282

Query: 64  YSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEEL 123
            +AE Q+++ +I         L+ KV SL++RL              EQ    EE ++EL
Sbjct: 283 -TAETQEKEDVITH-------LQEKVASLEKRL--------------EQNLSGEEHVQEL 320

Query: 124 KKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSIL 183
            K+    ++ L+D +++L+   +S    ++ +  R   +           E L+    I+
Sbjct: 321 LKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETR---VRELEQTLQASEEQLQQSKGIV 377

Query: 184 GVRREEMEQLFHDNQGS 200
             +  ++++L   NQ S
Sbjct: 378 AAQETQIQELAAANQES 394



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 47/256 (18%), Positives = 99/256 (38%), Gaps = 42/256 (16%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
           +N   +  V ++  QE L +  ++   +ALL   Q Q +  AL     +      ++E+ 
Sbjct: 512 QNLREKTEVLLQKEQEILQL--ERGHNSALLQIHQLQAELEALRTLKAEEAAVVAEQEDL 569

Query: 62  SMYSAELQKQKQLIAEWKKKAESLERKVISLQE--RLDEADA-ALDSASRLTEQLDLKEE 118
                 LQ +   + E    + +++  V  L    R    +  A+D      E+ DL+++
Sbjct: 570 LRLRGPLQAEALSVNESHVTSRAMQDPVFQLPTAGRTPNGEVGAMDLTQLQKEKQDLEQQ 629

Query: 119 QIEELKKQNEFQQEMLD------------------DVQKK----LVNLANSLEGKVDKV- 155
            +E+ K   + QQ ML+                  +V++K    + N+A S+    D   
Sbjct: 630 LLEKNKTIKQMQQRMLELRKTLQKELKIRPDNELFEVREKPGPEMANMAPSVTNNTDLTD 689

Query: 156 -------LMRNLFISHFHMPKNQRHEVLRLMGSILGVRREEMEQLFHDNQGSVTRWMTGW 208
                   ++++ +      +++   +++ +  +L   +EE   L          +   W
Sbjct: 690 AREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENML-----KETLEYKMSW 744

Query: 209 LGRGSKSVPNTPLRPN 224
              GSK  P   +RP+
Sbjct: 745 F--GSKPAPKGSIRPS 758



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 4/101 (3%)

Query: 41  QYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEAD 100
           +Y  SL N Q  L+   KEE S          Q + E +K+ E  +++  +L   +DE +
Sbjct: 453 EYERSLQNHQFELKKL-KEEWSQREIVSVAMAQALEEVRKQREEFQQQAANLTAIIDEKE 511

Query: 101 AALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKL 141
             L      TE L  KE++I +L++ +      +  +Q +L
Sbjct: 512 QNL---REKTEVLLQKEQEILQLERGHNSALLQIHQLQAEL 549



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 26/119 (21%), Positives = 56/119 (47%), Gaps = 9/119 (7%)

Query: 18  QLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAE 77
           +  +V+ +R   A  + ++Q ++Q     A L+     +++  ++ +  EL+K K+   E
Sbjct: 416 EAQIVALERTRAADQTTAEQGMRQLEQENAALKECRNEYERSLQN-HQFELKKLKE---E 471

Query: 78  WKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEE-----LKKQNEFQQ 131
           W ++         +L+E   + +     A+ LT  +D KE+ + E     L+K+ E  Q
Sbjct: 472 WSQREIVSVAMAQALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQ 530


>gi|51972208 leucine, glutamate and lysine rich 1 [Homo sapiens]
          Length = 388

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 45/164 (27%), Positives = 72/164 (43%), Gaps = 16/164 (9%)

Query: 5   SHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMY 64
           SHQ S+  E LQE L       D+        +  K+ A  L   +     F++E K   
Sbjct: 72  SHQKSI--EQLQETLRQ-KLLSDDNWKEKIEAELAKERAQHLVEFEEQALLFKEETKLQL 128

Query: 65  SAELQKQKQLIAEWKKKAESLERKVISL---------QERLDEADAALDSASRLTEQLDL 115
             E +K + +I ++KK+ E L+ K+  L         QE     +    S +R TE+ + 
Sbjct: 129 DIEKEKHQDVIQKYKKEQEELQMKISDLITGATRDLRQEVTTLKEKLHKSHTRYTEESNS 188

Query: 116 KEEQIEELKK-QNEFQQEM---LDDVQKKLVNLANSLEGKVDKV 155
           KE++IE LK    EF+  +   +D       NL   +E K D++
Sbjct: 189 KEKEIENLKNLVAEFESRLKKEIDSNDSVSENLRKEMEQKSDEL 232


>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
          Length = 1173

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 35/147 (23%), Positives = 68/147 (46%), Gaps = 16/147 (10%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           ++    Q + + +  Q +L+ VS + +    L   QQ+  Q+  S  N         K E
Sbjct: 682 LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNEL-------KSE 734

Query: 61  KSMYSAELQKQKQL---IAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
           K   S  LQ+++QL     E   + +SL R++   +E++   +  L+   +       KE
Sbjct: 735 KLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQE------KE 788

Query: 118 EQIEELKKQNEFQQEMLDDVQKKLVNL 144
           E I +    N+  Q+ L+D+++K+ N+
Sbjct: 789 ELINKKNTSNKIAQDKLNDIKEKVKNI 815



 Score = 36.6 bits (83), Expect = 0.035
 Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%)

Query: 28  ETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLER 87
           ++ +LS  Q ++K     L  L+       + ++ +  AE +  K   AE     E+L+ 
Sbjct: 307 KSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSK---AEKNSNVETLKM 363

Query: 88  KVISLQERLDEADAALDSASRLTEQLD---LKEEQIEELKKQNEFQQEMLDDVQKKLVNL 144
           +VISLQ    + D  L    +  EQL+       Q+E L K    + E +  ++ +  + 
Sbjct: 364 EVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDE 423

Query: 145 ANSLEG 150
             SL G
Sbjct: 424 LTSLLG 429


>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
          Length = 1312

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 35/147 (23%), Positives = 68/147 (46%), Gaps = 16/147 (10%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           ++    Q + + +  Q +L+ VS + +    L   QQ+  Q+  S  N         K E
Sbjct: 821 LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNEL-------KSE 873

Query: 61  KSMYSAELQKQKQL---IAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKE 117
           K   S  LQ+++QL     E   + +SL R++   +E++   +  L+   +       KE
Sbjct: 874 KLQISTNLQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQE------KE 927

Query: 118 EQIEELKKQNEFQQEMLDDVQKKLVNL 144
           E I +    N+  Q+ L+D+++K+ N+
Sbjct: 928 ELINKKNTSNKIAQDKLNDIKEKVKNI 954



 Score = 36.6 bits (83), Expect = 0.035
 Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%)

Query: 28  ETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLER 87
           ++ +LS  Q ++K     L  L+       + ++ +  AE +  K   AE     E+L+ 
Sbjct: 446 KSEILSKKQNELKNVKYELQQLEGSSDRILELDQELIKAERELSK---AEKNSNVETLKM 502

Query: 88  KVISLQERLDEADAALDSASRLTEQLD---LKEEQIEELKKQNEFQQEMLDDVQKKLVNL 144
           +VISLQ    + D  L    +  EQL+       Q+E L K    + E +  ++ +  + 
Sbjct: 503 EVISLQNEKADLDRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDE 562

Query: 145 ANSLEG 150
             SL G
Sbjct: 563 LTSLLG 568


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 31/147 (21%), Positives = 72/147 (48%), Gaps = 6/147 (4%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           M     Q   Q E ++EQ   + KQ+++T     + +Q +Q       ++   +  +++E
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316

Query: 61  KSMYSAELQKQKQLIAEWKKKAESLERK--VISLQERLDEADAAL----DSASRLTEQLD 114
           + M   E Q  KQ    W++K +  E+K  +   +E++ E +  +    +   +  EQ+ 
Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376

Query: 115 LKEEQIEELKKQNEFQQEMLDDVQKKL 141
            +EEQ+ + ++Q   Q+E + + ++++
Sbjct: 377 KQEEQMRKQEEQMRKQEEQMGEQKEQM 403



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 25/134 (18%), Positives = 69/134 (51%), Gaps = 4/134 (2%)

Query: 7   QASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA 66
           Q   Q E + EQ   + KQ ++   +   ++Q+++    +   +  +Q  Q+E+      
Sbjct: 200 QMGEQEEQMGEQEEQMQKQEEQ---MGEQEEQMRKQEEQMGEQEEQVQK-QEEQVQKQEE 255

Query: 67  ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQ 126
           +++KQ++ + E +++    E +++  +E+ ++ +   +   ++ EQ +   EQ E++++Q
Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315

Query: 127 NEFQQEMLDDVQKK 140
            E  +E  + + K+
Sbjct: 316 EEQMREQEEQMGKQ 329



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 11/138 (7%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQ--K 58
           M     Q   Q E ++EQ   + KQ ++         + K+        QM  Q  Q  +
Sbjct: 305 MREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE--------QMWKQEEQMGE 356

Query: 59  EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEE 118
           +E+ M   E Q +KQ   + +K+ E + ++   ++++ ++     +      EQ+  +EE
Sbjct: 357 QEEQMQKQEEQVRKQE-EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEE 415

Query: 119 QIEELKKQNEFQQEMLDD 136
           Q+ E K+Q   Q+E + +
Sbjct: 416 QMGEQKEQMRKQEEHMGE 433



 Score = 32.7 bits (73), Expect = 0.50
 Identities = 32/195 (16%), Positives = 87/195 (44%), Gaps = 11/195 (5%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           M+    Q   Q E +++Q   + +Q ++       Q+Q +Q       ++   +  +++E
Sbjct: 215 MQKQEEQMGEQEEQMRKQEEQMGEQEEQV------QKQEEQVQKQEEQMRKQEEQMREQE 268

Query: 61  KSMYSAELQ--KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEE 118
           + M   E Q  KQK+   + ++  E  E+     ++  ++ +   +   ++ EQ +   +
Sbjct: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328

Query: 119 QIEELKKQNE---FQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEV 175
           Q E++ +Q E    Q+E +   ++++      ++ + ++V  +   +        ++ E 
Sbjct: 329 QEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388

Query: 176 LRLMGSILGVRREEM 190
           +R     +G ++E+M
Sbjct: 389 MRKQEEQMGEQKEQM 403



 Score = 32.0 bits (71), Expect = 0.86
 Identities = 26/147 (17%), Positives = 69/147 (46%), Gaps = 15/147 (10%)

Query: 7   QASVQVESLQEQLNVVSKQ----RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKS 62
           Q   Q   ++EQ   V +Q    R++   +   + QV++    +   +  +   Q+E+  
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE-QEEQMG 209

Query: 63  MYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEE 122
               ++QKQ++ + E +++    E ++   +E++ + +          EQ+  +EEQ+ +
Sbjct: 210 EQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE----------EQVQKQEEQMRK 259

Query: 123 LKKQNEFQQEMLDDVQKKLVNLANSLE 149
            ++Q   Q+E + + +++++      E
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTE 286


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 33/135 (24%), Positives = 66/135 (48%), Gaps = 12/135 (8%)

Query: 26   RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESL 85
            +++T LL      V +      +LQ  LQ  +K+ +++   + + + Q IA+  K+ E L
Sbjct: 2010 KEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQ-IAQLNKEKELL 2068

Query: 86   ERKVISLQERLDEAD-----------AALDSASRLTEQLDLKEEQIEELKKQNEFQQEML 134
             ++  SLQ RL E+D           AAL        +L   +E++ +L++  E  +  +
Sbjct: 2069 VKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRI 2128

Query: 135  DDVQKKLVNLANSLE 149
            +  +KK +++A  L+
Sbjct: 2129 EADEKKQLHIAEKLK 2143



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 31/141 (21%), Positives = 64/141 (45%), Gaps = 16/141 (11%)

Query: 11  QVESLQEQLNVVSKQRDE-TALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA--E 67
           +++  +   NV+  + D+ T++    +  ++++   L   +   Q  Q +E  +  +  E
Sbjct: 424 ELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEE 483

Query: 68  LQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQN 127
           ++K+  L+   K  +E   R+V  L+  L      L+ +    E          E+K +N
Sbjct: 484 MKKENNLL---KSHSEQKAREVCHLEAELKNIKQCLNQSQNFAE----------EMKAKN 530

Query: 128 EFQQEMLDDVQKKLVNLANSL 148
             Q+ ML D+Q+K+    NSL
Sbjct: 531 TSQETMLRDLQEKINQQENSL 551



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 40/197 (20%), Positives = 88/197 (44%), Gaps = 33/197 (16%)

Query: 5   SHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMY 64
           S ++  ++E+ Q   N    Q    +L  + + Q +  +      + ++Q   + E+++ 
Sbjct: 809 SERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLM 868

Query: 65  SAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASR----LTEQLDLKEEQI 120
            AE Q  +  +AE  ++   L+    + Q  + E  +AL++  +    L ++++ ++ +I
Sbjct: 869 KAE-QMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEI 927

Query: 121 EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMG 180
           +ELKK N   ++ L ++Q  L++   SLE K                           M 
Sbjct: 928 QELKKSNHLLEDSLKELQ--LLSETLSLEKKE--------------------------MS 959

Query: 181 SILGVRREEMEQLFHDN 197
           SI+ + + E+E+L  +N
Sbjct: 960 SIISLNKREIEELTQEN 976



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 35/159 (22%), Positives = 73/159 (45%), Gaps = 16/159 (10%)

Query: 7   QASVQVESLQEQLNVVS------KQRDETALLSASQ---QQVKQYALSLANLQMVLQHFQ 57
           QAS +  +L+++L  ++      +Q  E+A  S  Q   ++ K++   L+  Q   Q   
Sbjct: 352 QASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLD 411

Query: 58  KE---EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLD 114
           +E    K+  + ELQ+ K +    + + + L      L+  L+E    L  A +  +   
Sbjct: 412 QECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQ 471

Query: 115 LKEEQI----EELKKQNEFQQEMLDDVQKKLVNLANSLE 149
           +KE ++    EE+KK+N   +   +   +++ +L   L+
Sbjct: 472 IKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELK 510



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 40/172 (23%), Positives = 77/172 (44%), Gaps = 24/172 (13%)

Query: 7    QASVQVESLQEQLN-----VVSKQRDETALLSASQQ---QVKQYALSLANLQMVLQHFQK 58
            ++S  +E LQ QL      V +   D+ A  +  Q    QV+   L  A L   L    K
Sbjct: 2435 KSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDE-AK 2493

Query: 59   EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRL--------T 110
                +  + +    Q + + K+K E  + ++  L+ ++ + +  +   S++         
Sbjct: 2494 NNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKE 2553

Query: 111  EQLDLK------EEQIEELKKQNEFQQEMLDDVQKKLVNLANSLE-GKVDKV 155
            + L+L+      E++I+ L+ +N   Q+ L+ +Q    NL N LE  K+DK+
Sbjct: 2554 QNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKM 2605



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 28/114 (24%), Positives = 61/114 (53%), Gaps = 6/114 (5%)

Query: 37  QQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERL 96
           Q++++    L  L+   Q  Q +  S+ +A LQKQKQ +   K +  +L+R+     +RL
Sbjct: 18  QKIQELEGQLDKLKKEKQQRQFQLDSLEAA-LQKQKQKVENEKTEGTNLKRE----NQRL 72

Query: 97  DEADAALD-SASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
            E   +L+ +  +++ +L +KE Q+   + Q    ++ ++ ++++L    + LE
Sbjct: 73  MEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELE 126



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 41/195 (21%), Positives = 82/195 (42%), Gaps = 18/195 (9%)

Query: 2    ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQ--HFQKE 59
            EN      +    + E    +SK +++T   SA Q  V +   +L N +  LQ  + + E
Sbjct: 865  ENLMKAEQMHQSFVAETSQRISKLQEDT---SAHQNVVAETLSALENKEKELQLLNDKVE 921

Query: 60   EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
             +     EL+K   L+ +  K+ + L  + +SL+++             ++  + L + +
Sbjct: 922  TEQAEIQELKKSNHLLEDSLKELQLLS-ETLSLEKK------------EMSSIISLNKRE 968

Query: 120  IEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLM 179
            IEEL ++N   +E+   + ++ +NL    E   + +  R   IS       Q   +L   
Sbjct: 969  IEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQR 1028

Query: 180  GSILGVRREEMEQLF 194
                G   E++ Q +
Sbjct: 1029 CEETGNAYEDLSQKY 1043



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 30/160 (18%), Positives = 74/160 (46%), Gaps = 11/160 (6%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKE- 59
           +++ S Q + +V  L+ +L  + +       L+ SQ   ++      + + +L+  Q++ 
Sbjct: 491 LKSHSEQKAREVCHLEAELKNIKQ------CLNQSQNFAEEMKAKNTSQETMLRDLQEKI 544

Query: 60  EKSMYSAELQKQKQLIAEWKKKAES----LERKVISLQERLDEADAALDSASRLTEQLDL 115
            +   S  L+K K  +A+ +K+ +     L+++   +++  D+       +  L   L+L
Sbjct: 545 NQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALEL 604

Query: 116 KEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
           K+++ EELK++         + +K L  + +  E    K+
Sbjct: 605 KKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKI 644



 Score = 32.0 bits (71), Expect = 0.86
 Identities = 38/163 (23%), Positives = 77/163 (47%), Gaps = 28/163 (17%)

Query: 2    ENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEK 61
            E+ S QA +  ES  E+LNV       +  L A+  +  ++AL L++ Q           
Sbjct: 2071 ESESLQARLS-ESDYEKLNV-------SKALEAALVEKGEFALRLSSTQ----------- 2111

Query: 62   SMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEA----DAALDSASRLTEQLDLKE 117
                 E+ + ++ I + + + E+ E+K + + E+L E     D+  D    L  +L + E
Sbjct: 2112 ----EEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSE 2167

Query: 118  EQIEELKKQNEFQQEMLDDVQKKLVNLANSLE-GKVDKVLMRN 159
            E  E +    E  +  ++ ++ ++  +A SL+  ++D V +R+
Sbjct: 2168 ENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRS 2210



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 33/140 (23%), Positives = 59/140 (42%), Gaps = 14/140 (10%)

Query: 15   LQEQLNVV-SKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQ 73
            L++++ V+ SK       L   Q   K     L   +M    F ++   M + E + Q++
Sbjct: 2565 LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQRE 2624

Query: 74   LIAEWKKKAESLERKVISLQERLD-EADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
            +          + +K   LQE L  E +        L E++   ++Q++EL  +N   ++
Sbjct: 2625 M--------HEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKK 2676

Query: 133  MLDDVQKKLVNLANSLEGKV 152
             LD + K  V      EGKV
Sbjct: 2677 SLDCMHKDQV----EKEGKV 2692



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 19/83 (22%), Positives = 43/83 (51%), Gaps = 3/83 (3%)

Query: 73  QLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
           Q I E + + + L+++    Q +LD  +AAL    +  E    ++ +   LK++N+   E
Sbjct: 18  QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVEN---EKTEGTNLKRENQRLME 74

Query: 133 MLDDVQKKLVNLANSLEGKVDKV 155
           + + ++K    +++ L+ K  +V
Sbjct: 75  ICESLEKTKQKISHELQVKESQV 97



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 30/135 (22%), Positives = 59/135 (43%), Gaps = 8/135 (5%)

Query: 11   QVESLQEQLNVVSKQRDET--ALLSASQQQVKQYAL---SLANLQMVLQHFQKEEKSMYS 65
            +++S ++QL  ++ +  E   +L    + QV++       +A  Q+ L   +K+ +++  
Sbjct: 2656 EIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALL- 2714

Query: 66   AELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKK 125
              L   KQ   E +   E L  K   L  +  E D    S   L   L    + +EELKK
Sbjct: 2715 --LDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKK 2772

Query: 126  QNEFQQEMLDDVQKK 140
                  + ++ ++K+
Sbjct: 2773 TKMDNLKYVNQLKKE 2787


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 34/160 (21%), Positives = 77/160 (48%), Gaps = 14/160 (8%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
            +E+   +    ++ L+  L  V K++       A++ +VK     +A L  ++    KE+
Sbjct: 943  LEDECSELKRDIDDLELTLAKVEKEKH------ATENKVKNLTEEMAGLDEIIAKLTKEK 996

Query: 61   KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
            K++  A  Q    L AE + K  +L +  + L++++D+ + +L+   ++   L+  + ++
Sbjct: 997  KALQEAHQQALDDLQAE-EDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL 1055

Query: 121  E-ELKKQNEF------QQEMLDDVQKKLVNLANSLEGKVD 153
            E +LK   E        ++ LD+  KK     N+L  +++
Sbjct: 1056 EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIE 1095



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 36/200 (18%)

Query: 1    MENASHQASVQVESLQ---EQLNVVS-----KQRDETALLSASQQQVKQYALSLANLQMV 52
            +E   H+   ++E L    E+ N  +     KQR+   +L+  +Q+ ++        Q  
Sbjct: 1414 LEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEES-------QSE 1466

Query: 53   LQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQ 112
            L+  QKE +S+ S EL K K    E  +  E+ +R+  +LQE + +          LTEQ
Sbjct: 1467 LESSQKEARSL-STELFKLKNAYEESLEHLETFKRENKNLQEEISD----------LTEQ 1515

Query: 113  LDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQR 172
            L    + I EL+K  +  +    ++Q  L     SLE +  K+L   L  +       ++
Sbjct: 1516 LGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1575

Query: 173  HEVLRLMGSILGVRREEMEQ 192
                      L  + EEMEQ
Sbjct: 1576 ----------LAEKDEEMEQ 1585



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 30/127 (23%), Positives = 67/127 (52%), Gaps = 4/127 (3%)

Query: 7    QASVQVESLQEQ-LNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYS 65
            + S +V+ L  Q  +++++++   A LS  Q +V++      N +   +     + +M +
Sbjct: 1708 ETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK-AITDAAMMA 1766

Query: 66   AELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKK 125
             EL+K++   A  ++  +++E+ +  LQ RLDEA+       +  +QL   E ++ EL+ 
Sbjct: 1767 EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGK--KQLQKLEARVRELEN 1824

Query: 126  QNEFQQE 132
            + E +Q+
Sbjct: 1825 ELEAEQK 1831



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 51/238 (21%), Positives = 95/238 (39%), Gaps = 46/238 (19%)

Query: 1    MENASHQASVQVE----------SLQEQLNVVSKQRDETA--LLSASQQQVKQYALSLAN 48
            +E A    SVQ+E           ++  L   + Q + TA  L       V +    + N
Sbjct: 1150 LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN 1209

Query: 49   LQMVLQHFQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASR 108
            LQ V Q  +KE KS +  EL      + +  K   +LE+   +L+++++E  +  +   R
Sbjct: 1210 LQRVKQKLEKE-KSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQR 1268

Query: 109  ------------------LTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEG 150
                              L+ QLD KE  I +L +      + L+D++++L         
Sbjct: 1269 SVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQL--------- 1319

Query: 151  KVDKVLMRNLFISHFHMPKNQRH--EVLRLMGSILGVRREEMEQLFHDNQGSVTRWMT 206
              ++V  +N      H  ++ RH  ++LR         + E++++       V +W T
Sbjct: 1320 -EEEVKAKNALA---HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1373



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 34/156 (21%)

Query: 11   QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ- 69
            Q+E L+ QL    K ++  A           +AL  A     L   Q EE++   AELQ 
Sbjct: 1311 QLEDLKRQLEEEVKAKNALA-----------HALQSARHDCDLLREQYEEETEAKAELQR 1359

Query: 70   ---KQKQLIAEWKKK--------AESLERKVISLQERLDEADAALDSASRLTEQLDLKEE 118
               K    +A+W+ K         E LE     L +RL EA+ A+++ +     L+  + 
Sbjct: 1360 VLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKH 1419

Query: 119  QIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDK 154
            ++     QNE +  M+D      V  +N+    +DK
Sbjct: 1420 RL-----QNEIEDLMVD------VERSNAAAAALDK 1444



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 30/150 (20%), Positives = 72/150 (48%), Gaps = 10/150 (6%)

Query: 7    QASVQVESLQEQLNVVSKQRDE-TALLSASQQQVKQYALSLANLQMVLQHFQKEEKSM-- 63
            Q   +V+ + E+L    +   E TA     + +  +    + +L++ L   +KE+ +   
Sbjct: 914  QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATEN 973

Query: 64   ----YSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
                 + E+    ++IA+  K+ ++L+    + Q+ LD+  A  D  + LT+     E+Q
Sbjct: 974  KVKNLTEEMAGLDEIIAKLTKEKKALQE---AHQQALDDLQAEEDKVNTLTKAKVKLEQQ 1030

Query: 120  IEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
            +++L+   E ++++  D+++    L   L+
Sbjct: 1031 VDDLEGSLEQEKKVRMDLERAKRKLEGDLK 1060



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 30/153 (19%), Positives = 74/153 (48%), Gaps = 11/153 (7%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
            ++ A  QA   +++ ++++N ++K + +       +QQV     SL   + V    ++ +
Sbjct: 999  LQEAHQQALDDLQAEEDKVNTLTKAKVKL------EQQVDDLEGSLEQEKKVRMDLERAK 1052

Query: 61   KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLK---- 116
            + +   +L+  ++ I + +   + L+ ++      L+  +A ++    L  QL  K    
Sbjct: 1053 RKL-EGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKEL 1111

Query: 117  EEQIEELKKQNEFQQEMLDDVQKKLVNLANSLE 149
            + +IEEL+++ E ++     V+K   +L+  LE
Sbjct: 1112 QARIEELEEELEAERTARAKVEKLRSDLSRELE 1144



 Score = 33.5 bits (75), Expect = 0.29
 Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 22/133 (16%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQKE 59
            +EN   Q   +++    +LN ++ +  DE AL S  Q+++K+    +  L+         
Sbjct: 1069 LENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE--------- 1119

Query: 60   EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
                   EL+ ++   A+ +K    L R++  + ERL+EA  A       + Q+++ +++
Sbjct: 1120 ------EELEAERTARAKVEKLRSDLSRELEEISERLEEAGGA------TSVQIEMNKKR 1167

Query: 120  IEELKKQNEFQQE 132
              E +K     +E
Sbjct: 1168 EAEFQKMRRDLEE 1180



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 37/208 (17%), Positives = 86/208 (41%), Gaps = 26/208 (12%)

Query: 7    QASVQVESLQEQLNVVSKQRDETAL--------LSASQQQVKQYALSLANLQMVLQHFQK 58
            +A  QV+SLQ  L     Q D+           ++  +++       L  L+ V++  ++
Sbjct: 1638 EAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTER 1697

Query: 59   EEK-----------------SMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADA 101
              K                 S  ++ + ++K++ A+  +    +E  V   +   ++A  
Sbjct: 1698 SRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKK 1757

Query: 102  ALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLF 161
            A+  A+ + E+L  +++    L++  +  ++ + D+Q +L + A  +  K  K  ++ L 
Sbjct: 1758 AITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRL-DEAEQIALKGGKKQLQKLE 1816

Query: 162  ISHFHMPKNQRHEVLRLMGSILGVRREE 189
                 +      E  R   S+ G+R+ E
Sbjct: 1817 ARVRELENELEAEQKRNAESVKGMRKSE 1844



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 25/111 (22%), Positives = 50/111 (45%), Gaps = 15/111 (13%)

Query: 57  QKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISL--------------QERLDEADAA 102
           +KE  SM   E  + K+ + + + + + LE K++SL              Q+ L +A+  
Sbjct: 846 EKEMASM-KEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER 904

Query: 103 LDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVD 153
            D   +   QL+ K +++ E  +  E     L   ++KL +  + L+  +D
Sbjct: 905 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDID 955



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 26/119 (21%), Positives = 53/119 (44%), Gaps = 7/119 (5%)

Query: 11   QVESLQEQLNVVSKQRDETAL----LSASQQQVKQYALSLANLQMVLQHFQKE---EKSM 63
            QV+ L+  L    K R +       L    +  ++  + L N +  L    K+   E + 
Sbjct: 1030 QVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNA 1089

Query: 64   YSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEE 122
             +A ++ ++ L ++ +KK + L+ ++  L+E L+    A     +L   L  + E+I E
Sbjct: 1090 LNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1148



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 30/161 (18%), Positives = 69/161 (42%), Gaps = 5/161 (3%)

Query: 4    ASHQASVQVESLQE----QLNVVSKQRDETALLSASQQQV-KQYALSLANLQMVLQHFQK 58
            A   A  +VE L+     +L  +S++ +E    ++ Q ++ K+       ++  L+    
Sbjct: 1124 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1183

Query: 59   EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEE 118
            + ++  +A  +K    +AE  ++ ++L+R    L++   E    LD  +   EQ+   + 
Sbjct: 1184 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKA 1243

Query: 119  QIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRN 159
             +E++ +  E Q        ++     N L  +  K+   N
Sbjct: 1244 NLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN 1284



 Score = 28.5 bits (62), Expect = 9.5
 Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 18/171 (10%)

Query: 3    NASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANL-----QMVLQHFQ 57
            NA  +A   +         + K++D +A L   ++ ++Q    L +      Q+ L+  +
Sbjct: 1750 NAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGK 1809

Query: 58   KEEKSMYSA------ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTE 111
            K+ + + +       EL+ +++  AE  K     ER++  L  + +E    L     L +
Sbjct: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869

Query: 112  QLDLK----EEQIEELKKQNEFQQEMLDDVQKKL---VNLANSLEGKVDKV 155
            +L LK    + Q EE ++Q          VQ +L      A+  E +V+K+
Sbjct: 1870 KLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKL 1920


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 38/162 (23%), Positives = 79/162 (48%), Gaps = 16/162 (9%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQR-DETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           ++ S +A  +V+ L E L  V  ++ D+   ++  ++QVK     +ANL+   Q  +K+ 
Sbjct: 748 KDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKS 807

Query: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDL----- 115
             M     +++  L    ++  +SL +K     +R++E + AL  + ++T + ++     
Sbjct: 808 AQMLEEARRREDNLNDSSQQLQDSLRKK----DDRIEELEEALRESVQITAEREMVLAQE 863

Query: 116 ------KEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGK 151
                  E+Q+EEL    E  ++ L+ ++ KL +   SL  K
Sbjct: 864 ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEK 905



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 42/172 (24%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQK-- 58
           + N    +   +E L+E L     +    A+L   Q +V    L L   + +L    K  
Sbjct: 492 LTNQFSDSKQHIEVLKESLTA---KEQRAAIL---QTEVDALRLRLEEKETMLNKKTKQI 545

Query: 59  ----EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDS--------- 105
               EEK   + E+   K ++   ++K   L++K+ +LQE+L + +  + S         
Sbjct: 546 QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 605

Query: 106 ---------ASRLTEQLDLKEEQIEELKKQNE----FQQEMLDDVQKKLVNL 144
                     + L E L  KE  IE LK+Q +     +QE +D+ +K L +L
Sbjct: 606 ADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDL 657



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 43/211 (20%), Positives = 89/211 (42%), Gaps = 33/211 (15%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           +E+   Q   +   L+E+++   +   ++A   A Q  ++     +++++  L+  ++E 
Sbjct: 346 LESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE- 404

Query: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
                 ++ K    ++  +++ E  + +V     +  +     +   +L E+L  KE Q 
Sbjct: 405 -----IQMLKSNGALSTEEREEEMKQMEVYRSHSKFMK-----NKVEQLKEELSSKEAQW 454

Query: 121 EELKKQ--------NEFQQEM------LDDVQKKLVNLANSLEGKVD--KVLMRNLFISH 164
           EELKK+         + +QE+      L  +Q KL  L N         +VL  +L    
Sbjct: 455 EELKKKAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESL---- 510

Query: 165 FHMPKNQRHEVLRLMGSILGVRREEMEQLFH 195
               K QR  +L+     L +R EE E + +
Sbjct: 511 --TAKEQRAAILQTEVDALRLRLEEKETMLN 539



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 34/163 (20%), Positives = 75/163 (46%), Gaps = 16/163 (9%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYA-LSLANLQMVLQHFQKE 59
           ++++  +   ++E L+E L    +   E  ++ A ++  +  A   +  L M ++  ++E
Sbjct: 828 LQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQE 887

Query: 60  EKSMYSAELQKQKQLIAE------------WKKKAESLERKVISLQERLDEADAALDSAS 107
            +SM  A+L   +Q +AE             K   E LE K  +L   + E DA + +  
Sbjct: 888 LESM-KAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI-ALL 945

Query: 108 RLTEQLDLKEEQIEELKKQNE-FQQEMLDDVQKKLVNLANSLE 149
            L+      +E++  LK++ +   Q++    Q ++  +A++ E
Sbjct: 946 ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYE 988


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 38/162 (23%), Positives = 79/162 (48%), Gaps = 16/162 (9%)

Query: 2   ENASHQASVQVESLQEQLNVVSKQR-DETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           ++ S +A  +V+ L E L  V  ++ D+   ++  ++QVK     +ANL+   Q  +K+ 
Sbjct: 720 KDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKS 779

Query: 61  KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDL----- 115
             M     +++  L    ++  +SL +K     +R++E + AL  + ++T + ++     
Sbjct: 780 AQMLEEARRREDNLNDSSQQLQDSLRKK----DDRIEELEEALRESVQITAEREMVLAQE 835

Query: 116 ------KEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGK 151
                  E+Q+EEL    E  ++ L+ ++ KL +   SL  K
Sbjct: 836 ESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEK 877



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 42/172 (24%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQK-- 58
           + N    +   +E L+E L     +    A+L   Q +V    L L   + +L    K  
Sbjct: 464 LTNQFSDSKQHIEVLKESLTA---KEQRAAIL---QTEVDALRLRLEEKETMLNKKTKQI 517

Query: 59  ----EEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDS--------- 105
               EEK   + E+   K ++   ++K   L++K+ +LQE+L + +  + S         
Sbjct: 518 QDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQ 577

Query: 106 ---------ASRLTEQLDLKEEQIEELKKQNE----FQQEMLDDVQKKLVNL 144
                     + L E L  KE  IE LK+Q +     +QE +D+ +K L +L
Sbjct: 578 ADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDL 629



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 34/163 (20%), Positives = 75/163 (46%), Gaps = 16/163 (9%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYA-LSLANLQMVLQHFQKE 59
           ++++  +   ++E L+E L    +   E  ++ A ++  +  A   +  L M ++  ++E
Sbjct: 800 LQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQE 859

Query: 60  EKSMYSAELQKQKQLIAE------------WKKKAESLERKVISLQERLDEADAALDSAS 107
            +SM  A+L   +Q +AE             K   E LE K  +L   + E DA + +  
Sbjct: 860 LESM-KAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI-ALL 917

Query: 108 RLTEQLDLKEEQIEELKKQNE-FQQEMLDDVQKKLVNLANSLE 149
            L+      +E++  LK++ +   Q++    Q ++  +A++ E
Sbjct: 918 ELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYE 960



 Score = 30.0 bits (66), Expect = 3.3
 Identities = 46/226 (20%), Positives = 94/226 (41%), Gaps = 40/226 (17%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQ--- 57
           +E      + + ES+++ L ++  +     L + + ++  +    LA  +M + H +   
Sbjct: 295 IETQKQTLNARDESIKKLLEMLQSK----GLSAKATEEDHERTRRLAEAEMHVHHLESLL 350

Query: 58  ---KEEKSMYSAELQ------------KQKQLIAEWK-KKAESLERKVISLQERLD--EA 99
              ++E SM   E+             K  Q + E K  K  S+ER +  L+E +   ++
Sbjct: 351 EQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKS 410

Query: 100 DAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV--LM 157
           + AL      TE+ + + +Q+E  +  ++F +  +  V+++L      L     K+  L 
Sbjct: 411 NGALS-----TEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLT 465

Query: 158 RNLFISHFHM--------PKNQRHEVLRLMGSILGVRREEMEQLFH 195
                S  H+         K QR  +L+     L +R EE E + +
Sbjct: 466 NQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLN 511


>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
            sapiens]
          Length = 1591

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 23/175 (13%)

Query: 1    MENASHQASVQVESLQEQLNVVSK-------QRDETA-LLSASQQQVKQYALSLANLQMV 52
            MEN  H  + +++ L++   +V +       + DE   LL A  Q ++Q  L      + 
Sbjct: 937  MENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQ 996

Query: 53   LQHFQKEEKSMYS-----AELQKQKQLIAEW--KKKAESLERKVISLQERLDEADAALDS 105
            ++H Q+ EK M        EL+K+ Q I     +  AE ++ K   LQE   +     D+
Sbjct: 997  VRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDT 1056

Query: 106  ASRLTEQLDLKEEQIEELK--------KQNEFQQEMLDDVQKKLVNLANSLEGKV 152
              +L  +L LKE + +E+K        +Q E  + +L+   + L    + L  K+
Sbjct: 1057 RCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKI 1111



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 42/174 (24%), Positives = 81/174 (46%), Gaps = 19/174 (10%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRDETALLSAS-QQQVKQYALSLANLQ--MVLQHFQ 57
            +E +  Q    ++SL EQ       R E + L+   Q   + Y + LA L+  M ++  Q
Sbjct: 1078 LEESRAQQKETLKSLLEQ--ETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQ 1135

Query: 58   ---------KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALD--SA 106
                     +EE ++  AEL K   L  +  +  ++L+ ++I LQ +LD   +AL+    
Sbjct: 1136 CISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKD 1195

Query: 107  SRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNL 160
             ++T+Q +  E  I+ L+K    +Q+++   ++    L   L  + D+ +   L
Sbjct: 1196 EKITQQEEKYEAIIQNLEKD---RQKLVSSQEQDREQLIQKLNCEKDEAIQTAL 1246


>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
            sapiens]
          Length = 1594

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 23/175 (13%)

Query: 1    MENASHQASVQVESLQEQLNVVSK-------QRDETA-LLSASQQQVKQYALSLANLQMV 52
            MEN  H  + +++ L++   +V +       + DE   LL A  Q ++Q  L      + 
Sbjct: 937  MENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSHLKELEDTLQ 996

Query: 53   LQHFQKEEKSMYS-----AELQKQKQLIAEW--KKKAESLERKVISLQERLDEADAALDS 105
            ++H Q+ EK M        EL+K+ Q I     +  AE ++ K   LQE   +     D+
Sbjct: 997  VRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDT 1056

Query: 106  ASRLTEQLDLKEEQIEELK--------KQNEFQQEMLDDVQKKLVNLANSLEGKV 152
              +L  +L LKE + +E+K        +Q E  + +L+   + L    + L  K+
Sbjct: 1057 RCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKI 1111



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 42/174 (24%), Positives = 81/174 (46%), Gaps = 19/174 (10%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRDETALLSAS-QQQVKQYALSLANLQ--MVLQHFQ 57
            +E +  Q    ++SL EQ       R E + L+   Q   + Y + LA L+  M ++  Q
Sbjct: 1078 LEESRAQQKETLKSLLEQ--ETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQ 1135

Query: 58   ---------KEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALD--SA 106
                     +EE ++  AEL K   L  +  +  ++L+ ++I LQ +LD   +AL+    
Sbjct: 1136 CISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKD 1195

Query: 107  SRLTEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNL 160
             ++T+Q +  E  I+ L+K    +Q+++   ++    L   L  + D+ +   L
Sbjct: 1196 EKITQQEEKYEAIIQNLEKD---RQKLVSSQEQDREQLIQKLNCEKDEAIQTAL 1246


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 11/135 (8%)

Query: 2    ENASHQASVQVESLQEQLNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
            E    + ++Q+ +L E L  V K+ +     +S  ++Q       +A L+  +Q+ Q E 
Sbjct: 1233 EENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDER 1292

Query: 61   KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
            +++    L+ + ++        E L+ KV+ LQ +LD   AA+    R  + L +K  Q 
Sbjct: 1293 RALLERCLKGEGEI--------EKLQTKVLELQRKLDNTTAAVQELGRENQSLQIKHTQA 1344

Query: 121  EELK--KQNEFQQEM 133
               K  + NE Q  M
Sbjct: 1345 LNRKWAEDNEVQNCM 1359



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 38/166 (22%), Positives = 77/166 (46%), Gaps = 15/166 (9%)

Query: 15  LQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAE--LQKQK 72
           LQ QL+   +Q  E   L  S     + A +  +L+ VL+    +++ + + E  LQK K
Sbjct: 479 LQHQLDKTKQQHQEQQALQQSTTAKLREAQN--DLEQVLRQIGDKDQKIQNLEALLQKSK 536

Query: 73  QLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEE----LKKQNE 128
           + I+  +K+ E L  K+     +  E + A+   ++L E+    +EQ+ +    LK Q+E
Sbjct: 537 ENISLLEKEREDLYAKI-----QAGEGETAV--LNQLQEKNHTLQEQVTQLTEKLKNQSE 589

Query: 129 FQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHE 174
             ++  +++  ++      L    D+VL     ++  +   N+  E
Sbjct: 590 SHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKE 635



 Score = 36.6 bits (83), Expect = 0.035
 Identities = 40/155 (25%), Positives = 72/155 (46%), Gaps = 28/155 (18%)

Query: 22  VSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSM------YSAELQKQKQLI 75
           V+  R E   L AS ++ K Y+  L       Q  Q++E          SAELQ  +Q +
Sbjct: 85  VTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQL 144

Query: 76  AE--------------WKKKAESLERKVISLQERLDEA----DAALDSASRLTEQLDLKE 117
            E              +++KA  L  ++  ++ + DE     +AA    +RLTE+L+ + 
Sbjct: 145 EEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEA 204

Query: 118 EQIEELKKQNEFQQEMLDDV---QKKLVNLANSLE 149
             I++LK +   Q+  ++DV   +K+LV +   ++
Sbjct: 205 TVIQDLKTE-LLQRPGIEDVAVLKKELVQVQTLMD 238



 Score = 36.6 bits (83), Expect = 0.035
 Identities = 42/186 (22%), Positives = 84/186 (45%), Gaps = 15/186 (8%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
           Q Q N+  + +++ A L A+Q +V     S+  L   L    KE+ S    +++ + +L+
Sbjct: 593 QAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNE-SKEKVSQLDIQIKAKTELL 651

Query: 76  --AEWKKKAES------LERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQ- 126
             AE  K A+       L+    +LQ++  E +       ++T +L  K+E   +L+   
Sbjct: 652 LSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHL 711

Query: 127 NEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSILGVR 186
            E++++ L   QK        LEG++ K+   +L +        Q  +  R + + L +R
Sbjct: 712 KEYKEKYLSLEQK-----TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELR 766

Query: 187 REEMEQ 192
             E+ +
Sbjct: 767 ATELSK 772



 Score = 36.2 bits (82), Expect = 0.045
 Identities = 36/158 (22%), Positives = 71/158 (44%), Gaps = 26/158 (16%)

Query: 2    ENASHQASVQVESLQEQL----NVVSKQRDETALLSASQQQVKQYA-------------L 44
            + ASHQ  +++ S+QEQL    N + +   E   L  +  ++KQ +             L
Sbjct: 923  KEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGEL 982

Query: 45   SLANLQMV-LQHFQKEEKSMYSAELQKQKQLIA----EWKKKAESLERKVISLQERLDEA 99
             +A LQ   L++  +++ +  + EL  +K+ I+     ++K  E+ ++       R  E 
Sbjct: 983  KIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESEL 1042

Query: 100  DAALDSASRLTEQLDLKEEQI----EELKKQNEFQQEM 133
             A       + E+L L +E +     ++  QN+  QE+
Sbjct: 1043 LATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQEL 1080



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 31/147 (21%), Positives = 69/147 (46%), Gaps = 1/147 (0%)

Query: 11   QVESLQEQLNVVSKQ-RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQ 69
            ++ +++++L+ VS   ++  +      Q+ K   L L      L+H  + +      E +
Sbjct: 854  ELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQK 913

Query: 70   KQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEF 129
            + K+ + + K+ +  L+ ++ S+QE+L +A   L    +  +QL     ++++  +Q + 
Sbjct: 914  ELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKK 973

Query: 130  QQEMLDDVQKKLVNLANSLEGKVDKVL 156
            Q E L    K  V     LE K+ + L
Sbjct: 974  QIEALQGELKIAVLQKTELENKLQQQL 1000



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 33/168 (19%), Positives = 75/168 (44%), Gaps = 32/168 (19%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDE-TALLSASQQQ-------VKQYALSLANLQMV 52
           ++N    A   ++  Q++LN ++ Q D+ TA L   Q+        +K+Y     +L+  
Sbjct: 665 LQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQK 724

Query: 53  LQHFQ-------------KEEKSMYSAELQKQKQLIAEWKKKAESL------ERKVIS-- 91
            +  +             K  K     +LQ+Q+QL  + + +A  L      E++++S  
Sbjct: 725 TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSST 784

Query: 92  ---LQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQEMLDD 136
              LQ++ +  ++     ++  E+  + ++  E L ++ + Q E L++
Sbjct: 785 RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNN 832



 Score = 32.7 bits (73), Expect = 0.50
 Identities = 34/152 (22%), Positives = 67/152 (44%), Gaps = 10/152 (6%)

Query: 7   QASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYAL-----SLANLQMVLQHFQKE-- 59
           Q   ++  L  +L    +Q  E       Q+Q+    L      +A+LQ+ L   +++  
Sbjct: 411 QLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLK 470

Query: 60  EKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQ 119
           EK   S ELQ Q     +  ++ ++L++   S   +L EA   L+   R     D K + 
Sbjct: 471 EKVTNSTELQHQLDKTKQQHQEQQALQQ---STTAKLREAQNDLEQVLRQIGDKDQKIQN 527

Query: 120 IEELKKQNEFQQEMLDDVQKKLVNLANSLEGK 151
           +E L ++++    +L+  ++ L     + EG+
Sbjct: 528 LEALLQKSKENISLLEKEREDLYAKIQAGEGE 559



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 30/134 (22%), Positives = 58/134 (43%), Gaps = 27/134 (20%)

Query: 10  VQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQK--EEKSMYSAE 67
           VQV++L + + +  ++R+   L    ++   QYA S A +  +     K  +E ++Y  E
Sbjct: 231 VQVQTLMDNMTL-ERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQE 289

Query: 68  LQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQN 127
           LQK K  + E  +K ++L                        TE L  KE+   +L++++
Sbjct: 290 LQKLKSSVNELTQKNQTL------------------------TENLLKKEQDYTKLEEKH 325

Query: 128 EFQQEMLDDVQKKL 141
             +     ++Q  L
Sbjct: 326 NEESVSKKNIQATL 339



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 30/154 (19%), Positives = 74/154 (48%), Gaps = 19/154 (12%)

Query: 9    SVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLA--------NLQMVLQHFQKEE 60
            S ++ES++E  N+    +D   LL   + +++  A SL         N Q++    +KEE
Sbjct: 1149 SHKLESIKEITNL----KDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEE 1204

Query: 61   KSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQI 120
            + +    ++K+ +L +E K+K   +++   +  +   +  A  ++   + ++    + ++
Sbjct: 1205 EELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRV 1264

Query: 121  EELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDK 154
             EL+KQ        DD++ ++  L  +++   D+
Sbjct: 1265 SELEKQT-------DDLRGEIAVLEATVQNNQDE 1291



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 37/158 (23%), Positives = 64/158 (40%), Gaps = 22/158 (13%)

Query: 1    MENASHQASVQVESLQEQLNVVSKQRD-----ETALLSASQQQVKQYALSLANLQMVLQH 55
            +++   + S+  E L    N +  Q       +TA  +  Q   K+    L      LQ 
Sbjct: 1049 LKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQ-QLQERCKALQD 1107

Query: 56   FQKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDL 115
             QKE KS+   EL  +K  +AE ++     E+++  L E L      L+S   +T   D 
Sbjct: 1108 IQKE-KSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEEL--KSHKLESIKEITNLKDA 1164

Query: 116  KE-------------EQIEELKKQNEFQQEMLDDVQKK 140
            K+             + ++   +Q +  Q++L D  KK
Sbjct: 1165 KQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKK 1202


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 42/190 (22%), Positives = 93/190 (48%), Gaps = 17/190 (8%)

Query: 15  LQEQLNVVSKQRDETAL-LSASQQQVKQYALSLAN--LQMVLQHFQKEEKSMYSAELQKQ 71
           LQE+L +V  ++ E  L +   ++++++  L L    LQ    H  KE +S+ SA+LQ Q
Sbjct: 226 LQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV-SAKLQAQ 284

Query: 72  KQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQ 131
            +    W +  +  E K+   +E++ E +  +       E++  +EE+I E +++   Q+
Sbjct: 285 VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE---EKIREQEEKIREQEEKMRRQE 341

Query: 132 EMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVLRLMGSILGVRRE--- 188
           EM+ + ++K+      +  K +K+  +   +        ++ E +R    ++  + E   
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW-------EKEEKMRRQEEMMWEKEEKIR 394

Query: 189 EMEQLFHDNQ 198
           E+E+  H+ +
Sbjct: 395 ELEEKMHEQE 404



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 28/130 (21%), Positives = 68/130 (52%), Gaps = 15/130 (11%)

Query: 11  QVESLQEQLNVVSKQ----RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA 66
           Q E +QEQ   + +Q    R++  +    ++++ +    +   +   +  Q++E++M+  
Sbjct: 617 QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE---EKMQEQEETMW-- 671

Query: 67  ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL-DSASRLTEQLDLKEEQIEELKK 125
              +Q++ I E +KK    E K+   +E + E +  + +   ++ EQ +  +EQ E++++
Sbjct: 672 ---RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 728

Query: 126 QNE--FQQEM 133
           Q E  ++QE+
Sbjct: 729 QEEKMWEQEV 738



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 24/130 (18%), Positives = 71/130 (54%), Gaps = 5/130 (3%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
           QE++    K++++   +   ++++++    +   +  ++  Q+E++     ++ KQ++ I
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE-QEEKRQEQEEKMWKQEEKI 614

Query: 76  AEWKKKAESLERKVISLQERL-DEADAALDSASRLTEQLDLKEEQIEELKKQNEF---QQ 131
            E ++K +  E K+   +E++ ++ +   +   ++ EQ +   EQ E++++Q E    Q+
Sbjct: 615 REQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQE 674

Query: 132 EMLDDVQKKL 141
           E + + +KK+
Sbjct: 675 EKIREQEKKI 684



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 23/134 (17%), Positives = 65/134 (48%), Gaps = 3/134 (2%)

Query: 57  QKEEKSMYSAELQKQKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLK 116
           Q+E+      ++ +Q++ I E ++K +  E K+   +E++ E +  +       E++  +
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE---EKIREQ 631

Query: 117 EEQIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKVLMRNLFISHFHMPKNQRHEVL 176
           EE+I E ++  + Q+E + + ++K+      ++ + + +  +   I        ++ E +
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691

Query: 177 RLMGSILGVRREEM 190
           R    ++  + E+M
Sbjct: 692 REQEEMMQEQEEKM 705



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 43/179 (24%), Positives = 83/179 (46%), Gaps = 32/179 (17%)

Query: 2   ENASHQASVQV---ESLQEQLNVVS-KQRDETALLSASQQQVKQYALSL--------ANL 49
           +NA  Q  +Q+   E  + QLNV   K++ E A L   QQQ++  A  L        A L
Sbjct: 222 KNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKL 281

Query: 50  QMVLQHF-------QKEEKSMYSAE---------LQKQKQLIAEWKKKAESLERKVISLQ 93
           Q  ++         Q++E+ M+  E         +Q+Q++ I E ++K    E K+   +
Sbjct: 282 QAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE 341

Query: 94  ERLDEADAALDSASRL----TEQLDLKEEQIEELKKQNEFQQEMLDDVQKKLVNLANSL 148
           E + E +  +     +     E++  +EE + E +++   Q+EM+ + ++K+  L   +
Sbjct: 342 EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 28/139 (20%), Positives = 72/139 (51%), Gaps = 16/139 (11%)

Query: 11  QVESLQEQLNVVSKQ----RDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSA 66
           Q E  QEQ   + KQ    R++   +   ++++++    +   + + Q  ++EEK     
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ--EQEEK----- 648

Query: 67  ELQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL-DSASRLTEQLDLKEEQIEELKK 125
            + +Q++ + E ++K +  E  +   +E++ E +  + +   ++ EQ ++ +EQ E++ +
Sbjct: 649 -MGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 707

Query: 126 QNEF---QQEMLDDVQKKL 141
           Q E    Q+E + + ++K+
Sbjct: 708 QEEKMCEQEEKMQEQEEKM 726



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 26/152 (17%), Positives = 75/152 (49%), Gaps = 7/152 (4%)

Query: 11  QVESLQEQLNVVSKQRDETALLSAS-QQQVKQYALSLANLQMVLQHFQKEEKSMYSAE-- 67
           Q E ++EQ   V +Q ++        Q+Q ++       ++   +  Q++E+ +   E  
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEK 634

Query: 68  LQKQKQLIAEWKKKAESLERKVISLQERLDEADAAL----DSASRLTEQLDLKEEQIEEL 123
           +++Q+++  E ++K    E K+   +E++ E +  +    +      +++  +EE+I E 
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694

Query: 124 KKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
           ++  + Q+E + + ++K+      ++ + +K+
Sbjct: 695 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 726



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 27/129 (20%), Positives = 63/129 (48%), Gaps = 16/129 (12%)

Query: 11  QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQK 70
           Q E ++EQ     K R +  ++   ++++++    +   +   +  +++E+ M+  E + 
Sbjct: 326 QEEKIREQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKE---EKMRRQEEMMWEKEEKM 379

Query: 71  QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQ 130
           ++Q    W+K     E K+  L+E++ E +       R  E+   +EE+I E +K+ E +
Sbjct: 380 RRQEEMMWEK-----EEKIRELEEKMHEQEKI-----REQEEKRQEEEKIREQEKRQEQE 429

Query: 131 QEMLDDVQK 139
            +M    +K
Sbjct: 430 AKMWRQEEK 438



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/117 (18%), Positives = 57/117 (48%), Gaps = 3/117 (2%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQKQKQLI 75
           QE++    K++++  +    ++  +Q  +     +M   H Q+E+      ++ +Q++ I
Sbjct: 463 QEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKM---HEQEEKIRKQEEKVWRQEEKI 519

Query: 76  AEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
            E ++K    E K+   +E++ E +       ++ EQ  + EE+  + ++   ++QE
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 26/145 (17%), Positives = 72/145 (49%), Gaps = 10/145 (6%)

Query: 11  QVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEEKSMYSAELQK 70
           Q E + EQ   + KQ ++   +   ++++++    +   +  +  +++EEK     E+ +
Sbjct: 494 QKEKMHEQEEKIRKQEEK---VWRQEEKIREQEEKIREQEEKM--WRQEEKIREQEEMWR 548

Query: 71  QKQLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQ 130
           +++ + E +K  E  +R     QE+ D+     +      E++  +EE+I E +++ + Q
Sbjct: 549 EEEKMHEQEKIWEEEKR-----QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ 603

Query: 131 QEMLDDVQKKLVNLANSLEGKVDKV 155
           +E +   ++K+      ++ + +K+
Sbjct: 604 EEKMWKQEEKIREQEEKIQEQEEKI 628



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 30/157 (19%), Positives = 73/157 (46%), Gaps = 12/157 (7%)

Query: 1   MENASHQASVQVESLQEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQKEE 60
           +E A    + Q +     +  ++K+RD  +L        + Y  ++ + ++  ++ + +E
Sbjct: 177 LEQALSAVATQKKKADRYIEELTKERDALSL--------ELYRNTITDEELKEKNAKLQE 228

Query: 61  KSMYSAELQKQKQL-IAEWKKKAESLERKVISLQERLD-EADAALDSASRLTEQLDLKEE 118
           K       + + QL + E K+K E    K++  Q++L  EAD        ++ +L  + E
Sbjct: 229 KLQLVESEKSEIQLNVKELKRKLE--RAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVE 286

Query: 119 QIEELKKQNEFQQEMLDDVQKKLVNLANSLEGKVDKV 155
           + E   + N+ Q+E +   ++K+      ++ + +K+
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKI 323



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 26/129 (20%), Positives = 63/129 (48%), Gaps = 8/129 (6%)

Query: 16  QEQLNVVSKQRDETALLSASQQQVKQYALSLANLQMVLQHFQK---EEKSMYSAELQKQK 72
           QE++    ++R E   +   +++ +Q A      + + +  +K   +EK M+     +Q+
Sbjct: 403 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW-----RQE 457

Query: 73  QLIAEWKKKAESLERKVISLQERLDEADAALDSASRLTEQLDLKEEQIEELKKQNEFQQE 132
           + I E +K  E  +R+      R +E     +   R  E++  +EE+I + +++   Q+E
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517

Query: 133 MLDDVQKKL 141
            + + ++K+
Sbjct: 518 KIREQEEKI 526


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,268,110
Number of Sequences: 37866
Number of extensions: 640120
Number of successful extensions: 6270
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 259
Number of HSP's successfully gapped in prelim test: 649
Number of HSP's that attempted gapping in prelim test: 3374
Number of HSP's gapped (non-prelim): 2802
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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