Search of human proteins with 169203660

Search of human proteins with 169203660

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]
         (198 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]          422   e-119
gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]          420   e-118
gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]          368   e-102
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]      113   1e-25
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H...   113   1e-25
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]     96   3e-20
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]     95   3e-20
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]    94   6e-20
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]    94   1e-19
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]    89   2e-18
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]       86   3e-17
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...    86   3e-17
gi|73808268 matrix metalloproteinase 27 [Homo sapiens]                 80   1e-15
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi...    79   2e-15
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein...    79   3e-15
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ...    79   3e-15
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi...    78   4e-15
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]    76   2e-14
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]    67   8e-12
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]     66   2e-11
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]    64   8e-11
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi...    63   2e-10
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap...    55   4e-08
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ...    52   4e-07
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi...    50   1e-06
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi...    50   2e-06
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot...    44   9e-05
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi...    35   0.032
gi|88853069 vitronectin precursor [Homo sapiens]                       35   0.042
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   34   0.071

>gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score =  422 bits (1085), Expect = e-119
 Identities = 198/198 (100%), Positives = 198/198 (100%)

Query: 1   MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRD 60
           MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRD
Sbjct: 1   MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRD 60

Query: 61  FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK 120
           FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK
Sbjct: 61  FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK 120

Query: 121 HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV 180
           HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV
Sbjct: 121 HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV 180

Query: 181 DAGYPKIIDDLPGISKKN 198
           DAGYPKIIDDLPGISKKN
Sbjct: 181 DAGYPKIIDDLPGISKKN 198


>gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 198

 Score =  420 bits (1079), Expect = e-118
 Identities = 197/198 (99%), Positives = 197/198 (99%)

Query: 1   MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRD 60
           MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWS ASALTFTRD
Sbjct: 1   MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRD 60

Query: 61  FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK 120
           FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK
Sbjct: 61  FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK 120

Query: 121 HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV 180
           HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV
Sbjct: 121 HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV 180

Query: 181 DAGYPKIIDDLPGISKKN 198
           DAGYPKIIDDLPGISKKN
Sbjct: 181 DAGYPKIIDDLPGISKKN 198


>gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
          Length = 358

 Score =  368 bits (944), Expect = e-102
 Identities = 173/174 (99%), Positives = 174/174 (100%)

Query: 25  EDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFY 84
           +DQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFY
Sbjct: 185 KDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFY 244

Query: 85  GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP 144
           GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP
Sbjct: 245 GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP 304

Query: 145 ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 198
           ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN
Sbjct: 305 ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 358



 Score = 59.3 bits (142), Expect = 2e-09
 Identities = 25/25 (100%), Positives = 25/25 (100%)

Query: 1  MGSDLRVYNTVFSPDDWRGIQKWQE 25
          MGSDLRVYNTVFSPDDWRGIQKWQE
Sbjct: 1  MGSDLRVYNTVFSPDDWRGIQKWQE 25


>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
          Length = 403

 Score =  113 bits (282), Expect = 1e-25
 Identities = 57/105 (54%), Positives = 70/105 (66%), Gaps = 7/105 (6%)

Query: 19  GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFV 72
           G  +W++       +NY P+LP+ DVD A  KAF+LWSN + LTFT+  E + DI++SFV
Sbjct: 39  GNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFV 98

Query: 73  FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFR 117
              D  DNSPF G  G LAHAF PGPGIGGD HFD DE  T +FR
Sbjct: 99  -RGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFR 142



 Score =  113 bits (282), Expect = 1e-25
 Identities = 54/92 (58%), Positives = 68/92 (73%), Gaps = 3/92 (3%)

Query: 107 DNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 166
           D DE R   F+ +K+W VQ   +L GYP+D+YSSF FP  VK IDAA+ E++TGKT+FFV
Sbjct: 270 DRDEVRF--FKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFV 327

Query: 167 ANEYWRYDENMQSVDAGYPKII-DDLPGISKK 197
           AN+YWRYDE  +S+D GYPK+I  D PGI  K
Sbjct: 328 ANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHK 359


>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
           sapiens]
          Length = 469

 Score =  113 bits (282), Expect = 1e-25
 Identities = 57/105 (54%), Positives = 70/105 (66%), Gaps = 7/105 (6%)

Query: 19  GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFV 72
           G  +W++       +NY P+LP+ DVD A  KAF+LWSN + LTFT+  E + DI++SFV
Sbjct: 105 GNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFV 164

Query: 73  FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFR 117
              D  DNSPF G  G LAHAF PGPGIGGD HFD DE  T +FR
Sbjct: 165 -RGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFR 208



 Score =  113 bits (282), Expect = 1e-25
 Identities = 54/92 (58%), Positives = 68/92 (73%), Gaps = 3/92 (3%)

Query: 107 DNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 166
           D DE R   F+ +K+W VQ   +L GYP+D+YSSF FP  VK IDAA+ E++TGKT+FFV
Sbjct: 336 DRDEVRF--FKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFV 393

Query: 167 ANEYWRYDENMQSVDAGYPKII-DDLPGISKK 197
           AN+YWRYDE  +S+D GYPK+I  D PGI  K
Sbjct: 394 ANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHK 425


>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
          Length = 467

 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 52/101 (51%), Positives = 63/101 (62%), Gaps = 7/101 (6%)

Query: 19  GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFV 72
           G  KW+        +NY P L + +V+RA   AFELWS AS L FTR  + E DI ++F 
Sbjct: 104 GNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAF- 162

Query: 73  FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
           +  D  DNSPF G +G LAHAF PG GIGGD HFD +ET T
Sbjct: 163 YQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWT 203



 Score = 72.8 bits (177), Expect = 2e-13
 Identities = 34/83 (40%), Positives = 54/83 (65%), Gaps = 4/83 (4%)

Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
           F+ +++W +    +L GYP+D+ S++ FP  V+ IDAA++ +   KT+FFV +++WRYD 
Sbjct: 344 FKGNQYWALSGYDILQGYPKDI-SNYGFPSSVQAIDAAVFYRS--KTYFFVNDQFWRYDN 400

Query: 176 NMQSVDAGYPKIIDD-LPGISKK 197
             Q ++ GYPK I    PGI  K
Sbjct: 401 QRQFMEPGYPKSISGAFPGIESK 423


>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
          Length = 477

 Score = 95.1 bits (235), Expect = 3e-20
 Identities = 49/117 (41%), Positives = 70/117 (59%), Gaps = 7/117 (5%)

Query: 19  GIQKWQEDQ------NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFV 72
           GI KW++        NY P+LP++ VD A  KA ++W   + LTF+R +E E DI++SF 
Sbjct: 105 GIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFA 164

Query: 73  FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQL 129
            + +  D  PF G    LAHA+ PGPGI GD HFD+DE  TKD   +  ++V   ++
Sbjct: 165 -VREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEI 220



 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 44/113 (38%), Positives = 70/113 (61%), Gaps = 9/113 (7%)

Query: 90  LAHAFPPGPGIGGDVHFDNDETRTKD----FRSSKHWVVQEDQLLSGYPRDVYSSFVFPE 145
           L  +F P    G D  +   E  +KD    F+ ++ W ++ +++ +GYPR +++   FP 
Sbjct: 328 LISSFWPSLPSGVDAAY---EVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHT-LGFPP 383

Query: 146 RVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK-IIDDLPGISKK 197
            V+KIDAAI +K+  KT+FFV ++YWR+DE   S++ G+PK I +D PGI  K
Sbjct: 384 TVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSK 436


>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
          Length = 476

 Score = 94.4 bits (233), Expect = 6e-20
 Identities = 48/120 (40%), Positives = 73/120 (60%), Gaps = 13/120 (10%)

Query: 19  GIQKWQEDQ------NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFV 72
           G+ KW++        NY P+LP++ VD A  KA ++W   + LTF+R +E E DI++SF 
Sbjct: 104 GMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFA 163

Query: 73  FLADLHDNSPFYGHDG---CLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQL 129
               + ++  FY  DG    LAHA+PPGPG+ GD+HFD+DE  T+D   +  ++V   +L
Sbjct: 164 ----VKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHEL 219



 Score = 86.7 bits (213), Expect = 1e-17
 Identities = 35/83 (42%), Positives = 62/83 (74%), Gaps = 2/83 (2%)

Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
           F+ ++ W ++ +++ +GYPR +++   FP  ++KIDAA+ +K+  KT+FF A++YWR+DE
Sbjct: 354 FKGNEFWAIRGNEVQAGYPRGIHT-LGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDE 412

Query: 176 NMQSVDAGYPKII-DDLPGISKK 197
           N QS++ G+P++I DD PG+  K
Sbjct: 413 NSQSMEQGFPRLIADDFPGVEPK 435


>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
          Length = 707

 Score = 93.6 bits (231), Expect = 1e-19
 Identities = 45/84 (53%), Positives = 57/84 (67%), Gaps = 1/84 (1%)

Query: 27  QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGH 86
           QNY  +LP+  +D A  +AF LWS  + LTFTR +  + DI++ F  +A+  D  PF G 
Sbjct: 126 QNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFG-VAEHGDGYPFDGK 184

Query: 87  DGCLAHAFPPGPGIGGDVHFDNDE 110
           DG LAHAFPPGPGI GD HFD+DE
Sbjct: 185 DGLLAHAFPPGPGIQGDAHFDDDE 208


>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
          Length = 471

 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 61/185 (32%), Positives = 93/185 (50%), Gaps = 22/185 (11%)

Query: 4   DLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFES 63
           D+  YN       W  +       NY P++   +V++A  KAF++WS+ + L FTR  + 
Sbjct: 100 DVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDG 159

Query: 64  EGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWV 123
             DI++SF  + +  D  PF G  G LAHAFPPGP  GGD HFD+DET T   +    ++
Sbjct: 160 IADIMISFG-IKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFL 218

Query: 124 VQEDQ----LLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQS 179
           V   +    L   + +D   + +FP         IY   TGK+HF +       D+++Q 
Sbjct: 219 VAAHEFGHSLGLDHSKDP-GALMFP---------IYTY-TGKSHFMLP------DDDVQG 261

Query: 180 VDAGY 184
           + + Y
Sbjct: 262 IQSLY 266



 Score = 75.1 bits (183), Expect = 4e-14
 Identities = 36/83 (43%), Positives = 50/83 (60%), Gaps = 2/83 (2%)

Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
           FR  K W +    +L GYP+ + S    P+ VKKI AA++ +DTGKT  F  N+ WRYD+
Sbjct: 349 FRGRKFWALNGYDILEGYPKKI-SELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDD 407

Query: 176 NMQSVDAGYPKII-DDLPGISKK 197
               +D  YP++I +D PGI  K
Sbjct: 408 TNHIMDKDYPRLIEEDFPGIGDK 430


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 55/154 (35%), Positives = 80/154 (51%), Gaps = 23/154 (14%)

Query: 22  KWQEDQ------NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLA 75
           KW ++Q       Y P+L  E VD A  +AF++WS+ + L F+R  + E DI+++F    
Sbjct: 68  KWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINF-GRW 126

Query: 76  DLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLS---G 132
           +  D  PF G DG LAHAF PG G+GGD HFD+DE           W + E Q++    G
Sbjct: 127 EHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDEL----------WTLGEGQVVRVKYG 176

Query: 133 YPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 166
                Y  F F    K+ ++     DTG++  F+
Sbjct: 177 NADGEYCKFPFLFNGKEYNSC---TDTGRSDGFL 207



 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 1/81 (1%)

Query: 110 ETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANE 169
           E +   F  +++W+     L  GYP+ + +S   P  V+++DAA       KT+ F  ++
Sbjct: 479 EEKAVFFAGNEYWIYSASTLERGYPKPL-TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 537

Query: 170 YWRYDENMQSVDAGYPKIIDD 190
           +WRY+E  + +D G+PK+I D
Sbjct: 538 FWRYNEVKKKMDPGFPKLIAD 558



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 2/49 (4%)

Query: 143 FPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDL 191
           +PE  +KIDA        K  FF  NEYW Y  +  +++ GYPK +  L
Sbjct: 463 WPELPEKIDAVYEAPQEEKAVFFAGNEYWIY--SASTLERGYPKPLTSL 509


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 55/154 (35%), Positives = 80/154 (51%), Gaps = 23/154 (14%)

Query: 22  KWQEDQ------NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLA 75
           KW ++Q       Y P+L  E VD A  +AF++WS+ + L F+R  + E DI+++F    
Sbjct: 118 KWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINF-GRW 176

Query: 76  DLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLS---G 132
           +  D  PF G DG LAHAF PG G+GGD HFD+DE           W + E Q++    G
Sbjct: 177 EHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDEL----------WTLGEGQVVRVKYG 226

Query: 133 YPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 166
                Y  F F    K+ ++     DTG++  F+
Sbjct: 227 NADGEYCKFPFLFNGKEYNSC---TDTGRSDGFL 257



 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 1/81 (1%)

Query: 110 ETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANE 169
           E +   F  +++W+     L  GYP+ + +S   P  V+++DAA       KT+ F  ++
Sbjct: 529 EEKAVFFAGNEYWIYSASTLERGYPKPL-TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 587

Query: 170 YWRYDENMQSVDAGYPKIIDD 190
           +WRY+E  + +D G+PK+I D
Sbjct: 588 FWRYNEVKKKMDPGFPKLIAD 608



 Score = 37.4 bits (85), Expect = 0.008
 Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 2/49 (4%)

Query: 143 FPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDL 191
           +PE  +KIDA        K  FF  NEYW Y  +  +++ GYPK +  L
Sbjct: 513 WPELPEKIDAVYEAPQEEKAVFFAGNEYWIY--SASTLERGYPKPLTSL 559


>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
          Length = 513

 Score = 79.7 bits (195), Expect = 1e-15
 Identities = 42/101 (41%), Positives = 55/101 (54%), Gaps = 4/101 (3%)

Query: 17  WRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLAD 76
           WR         NY P++ +  VD A  +  E+WS  + L FT+  +   DI+++F     
Sbjct: 106 WRKYNLTYRIINYTPDMARAAVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAF--RTR 163

Query: 77  LHDNSPFY--GHDGCLAHAFPPGPGIGGDVHFDNDETRTKD 115
           +H   P Y  G  G L HAFPPGPG+GGD HFD DE  TKD
Sbjct: 164 VHGRCPRYFDGPLGVLGHAFPPGPGLGGDTHFDEDENWTKD 204



 Score = 74.3 bits (181), Expect = 6e-14
 Identities = 37/101 (36%), Positives = 61/101 (60%), Gaps = 4/101 (3%)

Query: 98  PGIGGDVH--FDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIY 155
           P +  D+   ++N   +   F+    W+++   +L  YP+ +++   FP RVKKIDAA+ 
Sbjct: 323 PSLPADLQAAYENPRDKILVFKDENFWMIRGYAVLPDYPKSIHT-LGFPGRVKKIDAAVC 381

Query: 156 EKDTGKTHFFVANEYWRYDENMQSVDAGYP-KIIDDLPGIS 195
           +K T KT+FFV    WR+DE  Q++D G+P +++   PGIS
Sbjct: 382 DKTTRKTYFFVGIWCWRFDEMTQTMDKGFPQRVVKHFPGIS 422


>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
           sapiens]
          Length = 470

 Score = 79.3 bits (194), Expect = 2e-15
 Identities = 44/95 (46%), Positives = 54/95 (56%), Gaps = 3/95 (3%)

Query: 17  WRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLAD 76
           WR         NY P++ +EDVD A  KAF++WSN + L F++      DI++  VF   
Sbjct: 109 WRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILV--VFARG 166

Query: 77  LH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDE 110
            H D   F G  G LAHAF PG GIGGD HFD DE
Sbjct: 167 AHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDE 201



 Score = 77.4 bits (189), Expect = 7e-15
 Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 2/83 (2%)

Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
           F+  K+W++   +    YP+ ++S F FP  VKKIDAA++     +T+FFV N+YWRYDE
Sbjct: 347 FKDDKYWLISNLRPEPNYPKSIHS-FGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDE 405

Query: 176 NMQSVDAGYPKII-DDLPGISKK 197
             Q +D GYPK+I  +  GI  K
Sbjct: 406 RRQMMDPGYPKLITKNFQGIGPK 428


>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
           [Homo sapiens]
          Length = 457

 Score = 78.6 bits (192), Expect = 3e-15
 Identities = 43/105 (40%), Positives = 59/105 (56%), Gaps = 12/105 (11%)

Query: 21  QKWQED------QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESE-----GDIIL 69
           QKWQ        +N  P +   +  +A  +AF++W N + LTF     SE      D+ +
Sbjct: 125 QKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDI 184

Query: 70  SFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
           + +F +  H D+SPF G  G LAHA+ PGPGIGGD HFD+DE  T
Sbjct: 185 TIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT 229


>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
           [Homo sapiens]
          Length = 607

 Score = 78.6 bits (192), Expect = 3e-15
 Identities = 43/105 (40%), Positives = 59/105 (56%), Gaps = 12/105 (11%)

Query: 21  QKWQED------QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESE-----GDIIL 69
           QKWQ        +N  P +   +  +A  +AF++W N + LTF     SE      D+ +
Sbjct: 125 QKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDI 184

Query: 70  SFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
           + +F +  H D+SPF G  G LAHA+ PGPGIGGD HFD+DE  T
Sbjct: 185 TIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT 229



 Score = 72.0 bits (175), Expect = 3e-13
 Identities = 37/94 (39%), Positives = 56/94 (59%), Gaps = 5/94 (5%)

Query: 103 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYS--SFVFPERVKKIDAAIYEKDTG 160
           D  ++N +     F+ +K+WV ++  L  GYP D+ +  S + P     ID+AI+ +D G
Sbjct: 393 DAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHG---IDSAIWWEDVG 449

Query: 161 KTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 194
           KT+FF  + YWRY E M+++D GYPK I    GI
Sbjct: 450 KTYFFKGDRYWRYSEEMKTMDPGYPKPITVWKGI 483



 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 7/115 (6%)

Query: 82  PFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQ--LLSGYPRDVYS 139
           P Y HD     +  P  GI   + ++ D  +T  F+  ++W   E+   +  GYP+ +  
Sbjct: 421 PGYPHDLITLGSGIPPHGIDSAIWWE-DVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITV 479

Query: 140 SFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK-IIDDLPG 193
               PE  +    A   K+ G T+F+   EYW+++  +  V+ GYP+ I+ D  G
Sbjct: 480 WKGIPESPQ---GAFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMG 531


>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
           sapiens]
          Length = 483

 Score = 78.2 bits (191), Expect = 4e-15
 Identities = 43/101 (42%), Positives = 57/101 (56%), Gaps = 7/101 (6%)

Query: 19  GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFV 72
           G  KW+++        Y P++   +VD+A   A + WS+A  L+F R    E DI++SF 
Sbjct: 113 GEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFE 172

Query: 73  FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
              D  D+ PF G  G LAHAF PG G+GGD HFDN E  T
Sbjct: 173 N-GDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWT 212



 Score = 62.0 bits (149), Expect = 3e-10
 Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 1/84 (1%)

Query: 103 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKT 162
           D  ++  E  T  F    H+ +     + G PR +Y  F FP  V++IDAA+Y ++  KT
Sbjct: 348 DAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYD-FGFPRHVQQIDAAVYLREPQKT 406

Query: 163 HFFVANEYWRYDENMQSVDAGYPK 186
            FFV +EY+ YDE  + ++  YPK
Sbjct: 407 LFFVGDEYYSYDERKRKMEKDYPK 430



 Score = 27.7 bits (60), Expect = 6.7
 Identities = 13/38 (34%), Positives = 19/38 (50%), Gaps = 2/38 (5%)

Query: 134 PRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYW 171
           P  + SSF  P+ +  +DAA    + G  +FF    YW
Sbjct: 333 PSTITSSF--PQLMSNVDAAYEVAERGTAYFFKGPHYW 368


>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
          Length = 645

 Score = 75.9 bits (185), Expect = 2e-14
 Identities = 43/107 (40%), Positives = 59/107 (55%), Gaps = 16/107 (14%)

Query: 21  QKWQEDQ------NYMPNLPQEDVDRATGKAFELWSNASALTFT-------RDFESEGDI 67
           QKW++        NY P + + D  +A  +AF++W   + LTF        +    E DI
Sbjct: 161 QKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADI 220

Query: 68  ILSFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
           ++ F   +  H D+SPF G  G LAHA+ PGPGIGGD HFD+DE  T
Sbjct: 221 MIFFA--SGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT 265



 Score = 58.2 bits (139), Expect = 5e-09
 Identities = 32/92 (34%), Positives = 46/92 (50%), Gaps = 1/92 (1%)

Query: 103 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKT 162
           D  ++  + R   F+  K+WV +E  +  GYP  +        R + ID A+  +  GKT
Sbjct: 430 DAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPR-EGIDTALRWEPVGKT 488

Query: 163 HFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 194
           +FF    YWRY E  ++ D GYPK I    GI
Sbjct: 489 YFFKGERYWRYSEERRATDPGYPKPITVWKGI 520



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 6/89 (6%)

Query: 112 RTKDFRSSKHWVVQEDQLLS--GYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANE 169
           +T  F+  ++W   E++  +  GYP+ +      P+  +    A   K+   T+F+   +
Sbjct: 487 KTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQ---GAFISKEGYYTYFYKGRD 543

Query: 170 YWRYDENMQSVDAGYPK-IIDDLPGISKK 197
           YW++D    SV+ GYP+ I+ D  G ++K
Sbjct: 544 YWKFDNQKLSVEPGYPRNILRDWMGCNQK 572


>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
          Length = 582

 Score = 67.4 bits (163), Expect = 8e-12
 Identities = 44/126 (34%), Positives = 62/126 (49%), Gaps = 20/126 (15%)

Query: 22  KWQED------QNYMPNLPQEDVDRATGKAFELWSNASALTFTR--------DFESEGDI 67
           KWQ +      QNY P + +     A  KAF +W +A+ L F            E + DI
Sbjct: 118 KWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADI 177

Query: 68  ILSFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDE---TRTKDFRSSKHWV 123
           ++ F      H D++PF G  G LAHA+ PGP IGGD HFD+ E    R +D   +  ++
Sbjct: 178 MIFFA--EGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFL 235

Query: 124 VQEDQL 129
           V   +L
Sbjct: 236 VAVHEL 241



 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 32/79 (40%), Positives = 46/79 (58%), Gaps = 1/79 (1%)

Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
           F+  KHWV  E  L  GYP+ +           KIDAA++    GKT+FF  N+Y+R++E
Sbjct: 382 FKGDKHWVFDEASLEPGYPKHI-KELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNE 440

Query: 176 NMQSVDAGYPKIIDDLPGI 194
            +++VD+ YPK I    GI
Sbjct: 441 ELRAVDSEYPKNIKVWEGI 459



 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 11/79 (13%)

Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAI---YEKDTGKTHFFVANEYWR 172
           F+    W V+ +Q++ GYP  +   +      + + A+I   YE+  GK  FF  +++W 
Sbjct: 336 FKERWFWRVRNNQVMDGYPMPIGQFW------RGLPASINTAYERKDGKFVFFKGDKHWV 389

Query: 173 YDENMQSVDAGYPKIIDDL 191
           +DE   S++ GYPK I +L
Sbjct: 390 FDE--ASLEPGYPKHIKEL 406


>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
          Length = 267

 Score = 65.9 bits (159), Expect = 2e-11
 Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 28  NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87
           +Y  +LP   VDR   KA  +W     L F +      DI++ F   A   D+ PF G  
Sbjct: 115 SYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAH-GDSYPFDGPG 173

Query: 88  GCLAHAFPPGPGIGGDVHFDNDETRT 113
             LAHAF PG G+GGD HFD DE  T
Sbjct: 174 NTLAHAFAPGTGLGGDAHFDEDERWT 199


>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
          Length = 669

 Score = 63.9 bits (154), Expect = 8e-11
 Identities = 39/96 (40%), Positives = 50/96 (52%), Gaps = 11/96 (11%)

Query: 27  QNYMPNLPQEDVDRATGKAFELWSNASALTFTR--------DFESEGDIILSFVFLADLH 78
           QNY   L       A  +AF +W  A+ L F            + E DI++  +F +  H
Sbjct: 149 QNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMV--LFASGFH 206

Query: 79  -DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
            D+SPF G  G LAHA+ PGPG+GGD HFD DE  T
Sbjct: 207 GDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWT 242



 Score = 63.2 bits (152), Expect = 1e-10
 Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 3/98 (3%)

Query: 99  GIGGDVH--FDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYE 156
           G+ GD+   ++  + R   F+  ++W+ +E  L  GYP+ + +S+       +ID AI+ 
Sbjct: 414 GLPGDISAAYERQDGRFVFFKGDRYWLFREANLEPGYPQPL-TSYGLGIPYDRIDTAIWW 472

Query: 157 KDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 194
           + TG T FF  + YWR++E  Q  D GYPK I    GI
Sbjct: 473 EPTGHTFFFQEDRYWRFNEETQRGDPGYPKPISVWQGI 510



 Score = 38.5 bits (88), Expect = 0.004
 Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 5/75 (6%)

Query: 116 FRSSKHWVVQEDQLLS--GYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRY 173
           F+  ++W   E+      GYP+ +      P   K    A    D   T+F+   +YW++
Sbjct: 481 FQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPK---GAFLSNDAAYTYFYKGTKYWKF 537

Query: 174 DENMQSVDAGYPKII 188
           D     ++ GYPK I
Sbjct: 538 DNERLRMEPGYPKSI 552


>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
           sapiens]
          Length = 488

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 38/96 (39%), Positives = 49/96 (51%), Gaps = 11/96 (11%)

Query: 33  LPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDGCLAH 92
           L QE V +   +A ++WS+ + LTFT   E   DI++ F       D+ PF G  G LAH
Sbjct: 121 LVQEQVRQTMAEALKVWSDVTPLTFTEVHEGRADIMIDFARYWH-GDDLPFDGPGGILAH 179

Query: 93  AFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQ 128
           AF P     GDVHFD DET          W + +DQ
Sbjct: 180 AFFPKTHREGDVHFDYDET----------WTIGDDQ 205



 Score = 37.7 bits (86), Expect = 0.006
 Identities = 48/201 (23%), Positives = 77/201 (38%), Gaps = 23/201 (11%)

Query: 8   YNTVFSPDDWRGIQK-----WQEDQNYMPNL-PQEDVDRATGKAFELWSNASALTFTRDF 61
           Y    SPDD RG+Q      W    +  P L PQ  +D  T +   L  +A        F
Sbjct: 241 YPLSLSPDDCRGVQHLYGQPWPTVTSRTPALGPQAGID--TNEIAPLEPDAPPDACEASF 298

Query: 62  ES----EGDIIL---SFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTK 114
           ++     G++      FV+        P Y     LA     G     D  F++ +    
Sbjct: 299 DAVSTIRGELFFFKAGFVWRLRGGQLQPGYP---ALASRHWQGLPSPVDAAFEDAQGHIW 355

Query: 115 DFRSSKHWVVQ-EDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRY 173
            F+ +++WV   E  +L   P        FP       A ++  +  K +FF   +YWR+
Sbjct: 356 FFQGAQYWVYDGEKPVLGPAPLTELGLVRFPVHA----ALVWGPEKNKIYFFRGRDYWRF 411

Query: 174 DENMQSVDAGYPKIIDDLPGI 194
             + + VD+  P+   D  G+
Sbjct: 412 HPSTRRVDSPVPRRATDWRGV 432



 Score = 27.3 bits (59), Expect = 8.7
 Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)

Query: 149 KIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKII 188
           +IDAA  + D G  +F     YW++D        G+P+++
Sbjct: 435 EIDAAFQDAD-GYAYFLRGRLYWKFDPVKVKALEGFPRLV 473


>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
           sapiens]
          Length = 603

 Score = 55.1 bits (131), Expect = 4e-08
 Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 11/93 (11%)

Query: 101 GGDVHFDNDET---RTKD-----FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDA 152
           G  +H D+ +    RT D     F+  ++WV +++ +  GYPR V S F  P     IDA
Sbjct: 377 GLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPV-SDFSLPPG--GIDA 433

Query: 153 AIYEKDTGKTHFFVANEYWRYDENMQSVDAGYP 185
           A       +T+FF    YWRYD++ + +D GYP
Sbjct: 434 AFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYP 466



 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 34/76 (44%), Positives = 42/76 (55%), Gaps = 4/76 (5%)

Query: 45  AFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPG-PGIGGD 103
           A ++WS+ + L F     S  DI + F   AD +D  PF G  G +AHAF PG     GD
Sbjct: 163 ALKVWSDIAPLNFHEVAGSAADIQIDFS-KADHNDGYPFDGPGGTVAHAFFPGHHHTAGD 221

Query: 104 VHFDNDETRTKDFRSS 119
            HFD+DE  T  FRSS
Sbjct: 222 THFDDDEAWT--FRSS 235



 Score = 29.3 bits (64), Expect = 2.3
 Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 8/96 (8%)

Query: 93  AFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQED--QLLSGYPRDVYSSFVFPERVKKI 150
           + PPG GI     + +++ RT  F+   +W   +    +  GYP     S ++      +
Sbjct: 425 SLPPG-GIDAAFSWAHND-RTYFFKDQLYWRYDDHTRHMDPGYPAQ---SPLWRGVPSTL 479

Query: 151 DAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK 186
           D A+   D G ++FF   EYW+  +    V  GYP+
Sbjct: 480 DDAMRWSD-GASYFFRGQEYWKVLDGELEVAPGYPQ 514


>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
           [Homo sapiens]
          Length = 520

 Score = 51.6 bits (122), Expect = 4e-07
 Identities = 37/86 (43%), Positives = 45/86 (52%), Gaps = 7/86 (8%)

Query: 28  NYMPNLPQEDVDRATGKAFELWSNASALTF-TRDFESEGDIILSFVFLADLHD--NSPFY 84
           N+  +LP+  V  A   AF+LWSN SAL F         DI L+F F  D +D   + F 
Sbjct: 141 NWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTF-FQGDHNDGLGNAFD 199

Query: 85  GHDGCLAHAFPPGPGIGGDVHFDNDE 110
           G  G LAHAF P     G+ HFD DE
Sbjct: 200 GPGGALAHAFLPR---RGEAHFDQDE 222


>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
           sapiens]
          Length = 261

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 1/83 (1%)

Query: 28  NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87
           NY  ++    V  +   A  +WSN + L F +    + DI +SF   A   D  PF G  
Sbjct: 110 NYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAH-EDGWPFDGPG 168

Query: 88  GCLAHAFPPGPGIGGDVHFDNDE 110
           G L HAF P  G  G VHFD +E
Sbjct: 169 GILGHAFLPNSGNPGVVHFDKNE 191


>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
           sapiens]
          Length = 562

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 36/85 (42%), Positives = 42/85 (49%), Gaps = 5/85 (5%)

Query: 33  LPQEDVDRATGKAFELWSNASALTFTRDFESEG---DIILSFVFLADLHDNSPFYGHDGC 89
           L QE V      A   W   S LTF      +G   DI++ F   A   D+ PF G  G 
Sbjct: 133 LSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFA-RAFHQDSYPFDGLGGT 191

Query: 90  LAHAFPPGP-GIGGDVHFDNDETRT 113
           LAHAF PG   I GD HFD++ET T
Sbjct: 192 LAHAFFPGEHPISGDTHFDDEETWT 216



 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 3/71 (4%)

Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
           F   + WV Q+ QL  G  R +    + P   +++DA       GKT+     +YWRYDE
Sbjct: 385 FSGPQFWVFQDRQLEGG-ARPLTELGLPPG--EEVDAVFSWPQNGKTYLVRGRQYWRYDE 441

Query: 176 NMQSVDAGYPK 186
                D GYP+
Sbjct: 442 AAARPDPGYPR 452



 Score = 28.1 bits (61), Expect = 5.1
 Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 4/55 (7%)

Query: 132 GYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK 186
           GYPRD+      P     +  +    + G T+FF    YWR+ +N    +   P+
Sbjct: 449 GYPRDLSLWEGAPPSPDDVTVS----NAGDTYFFKGAHYWRFPKNSIKTEPDAPQ 499


>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
           [Homo sapiens]
          Length = 508

 Score = 43.9 bits (102), Expect = 9e-05
 Identities = 32/87 (36%), Positives = 39/87 (44%), Gaps = 3/87 (3%)

Query: 28  NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87
           N    LP      A  +AF+ WSN + LTF        DI LSF      + ++ F G  
Sbjct: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174

Query: 88  GCLAHAFPPGPGIGGDVHFDNDETRTK 114
             LAHA  P     G VHFD DE  T+
Sbjct: 175 RVLAHADIPEL---GSVHFDEDEFWTE 198



 Score = 34.7 bits (78), Expect = 0.054
 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 8/77 (10%)

Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVK-KIDAAIYEKDTGKTHFFVANEYWRYD 174
           F+  K W     ++  G+P+ +        RV+  +DAA+Y     K   F  + YW++D
Sbjct: 352 FKGDKVWRYINFKMSPGFPKKL-------NRVEPNLDAALYWPLNQKVFLFKGSGYWQWD 404

Query: 175 ENMQSVDAGYPKIIDDL 191
           E  ++  + YPK I  L
Sbjct: 405 ELARTDFSSYPKPIKGL 421



 Score = 34.3 bits (77), Expect = 0.071
 Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 10/77 (12%)

Query: 116 FRSSKHWVVQEDQL----LSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYW 171
           F+ S +W  Q D+L     S YP+ +   F     V    +A      G+ +FF    YW
Sbjct: 395 FKGSGYW--QWDELARTDFSSYPKPIKGLFT---GVPNQPSAAMSWQDGRVYFFKGKVYW 449

Query: 172 RYDENMQSVDAGYPKII 188
           R ++ ++ V+ GYP+ I
Sbjct: 450 RLNQQLR-VEKGYPRNI 465



 Score = 30.8 bits (68), Expect = 0.79
 Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 150 IDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK 186
           +DAA+Y   T   HFF  ++ WRY     S   G+PK
Sbjct: 337 LDAAVYSPRTQWIHFFKGDKVWRYINFKMS--PGFPK 371


>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
           sapiens]
          Length = 569

 Score = 35.4 bits (80), Expect = 0.032
 Identities = 27/77 (35%), Positives = 33/77 (42%), Gaps = 8/77 (10%)

Query: 37  DVDRATGKAFELWSNASALTFTRDFESEG---DIILSFVFLADLHDNSPFYGHDGCLAHA 93
           D  R    AF +WS  + L F  D  + G   DI L F     L     F G     AHA
Sbjct: 193 DQRRIVALAFRMWSEVTPLDFREDLAAPGAAVDIKLGFGRGRHLGCPRAFDGSGQEFAHA 252

Query: 94  FPPGPGIGGDVHFDNDE 110
           +  G     D+HFD+DE
Sbjct: 253 WRLG-----DIHFDDDE 264



 Score = 35.4 bits (80), Expect = 0.032
 Identities = 44/201 (21%), Positives = 81/201 (40%), Gaps = 34/201 (16%)

Query: 28  NYMPNLPQEDVDRATGKAFELWSNASALTFTRDFE-------SEGDIILSF--------- 71
           NY+P  P  ++D +  KA +    +   +F   F+         G++++ F         
Sbjct: 304 NYIPQEPAFELDWSDRKAIQKLYGSCEGSFDTAFDWIRKERNQYGEVMVRFSTYFFRNSW 363

Query: 72  VFLADLHDNSPFYGHDGCLAHAFP--PGPGIGGDVH---FDNDETRTKDFRSSKHW---- 122
            +L +  +N   YG    +   +P  P   I   VH   +  DE     F+ +++W    
Sbjct: 364 YWLYENRNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDERYF--FQGNQYWRYDS 421

Query: 123 ----VVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQ 178
                + ED+    YP+ +   F  P     +D A Y++     +FF  +  + +D N  
Sbjct: 422 DKDQALTEDEQGKSYPKLISEGF--PGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRN 479

Query: 179 SVDAGYPKIIDDL-PGISKKN 198
            V   YPK I ++ P +  +N
Sbjct: 480 RVLNSYPKRITEVFPAVIPQN 500



 Score = 31.2 bits (69), Expect = 0.60
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 90  LAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWV--VQEDQLLSGYPRDVYSSF--VFPE 145
           ++  FP  P       +D  +     F+ S  +   V  +++L+ YP+ +   F  V P+
Sbjct: 440 ISEGFPGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRNRVLNSYPKRITEVFPAVIPQ 499

Query: 146 R--VKKIDAAIYEKDTGKTHFFVANEYWR 172
               + ID+A Y        FF  N YW+
Sbjct: 500 NHPFRNIDSAYYSYAYNSIFFFKGNAYWK 528


>gi|88853069 vitronectin precursor [Homo sapiens]
          Length = 478

 Score = 35.0 bits (79), Expect = 0.042
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 12/79 (15%)

Query: 116 FRSSKHWVVQEDQLLSGYP---RDVYSSFVFPERVKKIDAAIYEKDT-GKTHFFVANEYW 171
           FR    + + E  +  GYP   RDV+           IDAA    +  GKT+ F  ++YW
Sbjct: 175 FRGQYCYELDEKAVRPGYPKLIRDVWGI------EGPIDAAFTRINCQGKTYLFKGSQYW 228

Query: 172 RYDENMQSVDAGYPKIIDD 190
           R+++ +  +D  YP+ I D
Sbjct: 229 RFEDGV--LDPDYPRNISD 245



 Score = 32.7 bits (73), Expect = 0.21
 Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 3/69 (4%)

Query: 108 NDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSF-VFPERVKKIDAAIYEKDTG--KTHF 164
           N + +T  F+ S++W  ++  L   YPR++   F   P+ V    A      +G  + +F
Sbjct: 214 NCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYF 273

Query: 165 FVANEYWRY 173
           F   +YW Y
Sbjct: 274 FKGKQYWEY 282


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 34.3 bits (77), Expect = 0.071
 Identities = 15/29 (51%), Positives = 21/29 (72%), Gaps = 2/29 (6%)

Query: 160  GKTHFFVANEYWRYDENMQSVDAGYPKII 188
            GKT FF  ++YWR+  +++  DAGYPK I
Sbjct: 1072 GKTFFFKDSQYWRFTNDIK--DAGYPKPI 1098



 Score = 28.5 bits (62), Expect = 3.9
 Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 2/60 (3%)

Query: 108  NDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSF--VFPERVKKIDAAIYEKDTGKTHFF 165
            N E +T  F+ S++W    D   +GYP+ ++  F  +  + V  +  A Y+      +FF
Sbjct: 1069 NCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYKNWPESVYFF 1128


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,718,205
Number of Sequences: 37866
Number of extensions: 394076
Number of successful extensions: 861
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 730
Number of HSP's gapped (non-prelim): 92
length of query: 198
length of database: 18,247,518
effective HSP length: 97
effective length of query: 101
effective length of database: 14,574,516
effective search space: 1472026116
effective search space used: 1472026116
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.