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Search of human proteins with 169202084
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]
(198 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens] 422 e-118
gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens] 420 e-118
gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens] 365 e-101
gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens] 113 1e-25
gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [H... 113 1e-25
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens] 96 2e-20
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens] 96 3e-20
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens] 95 4e-20
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 94 8e-20
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens] 89 3e-18
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 85 5e-17
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 85 5e-17
gi|73808268 matrix metalloproteinase 27 [Homo sapiens] 82 4e-16
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi... 78 6e-15
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens] 78 6e-15
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi... 77 7e-15
gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein... 76 2e-14
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ... 76 2e-14
gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens] 68 6e-12
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens] 67 1e-11
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens] 64 6e-11
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi... 62 3e-10
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap... 55 4e-08
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi... 50 1e-06
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ... 49 2e-06
gi|73808266 matrix metalloproteinase 26 preproprotein [Homo sapi... 48 6e-06
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot... 42 4e-04
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi... 36 0.024
gi|88853069 vitronectin precursor [Homo sapiens] 35 0.042
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 34 0.071
>gi|169202084 PREDICTED: similar to hCG2042634 [Homo sapiens]
Length = 198
Score = 422 bits (1084), Expect = e-118
Identities = 198/198 (100%), Positives = 198/198 (100%)
Query: 1 MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRD 60
MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRD
Sbjct: 1 MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRD 60
Query: 61 FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK 120
FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK
Sbjct: 61 FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK 120
Query: 121 HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV 180
HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV
Sbjct: 121 HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV 180
Query: 181 DAGYPKIIDDLPGISKKN 198
DAGYPKIIDDLPGISKKN
Sbjct: 181 DAGYPKIIDDLPGISKKN 198
>gi|169203660 PREDICTED: similar to hCG2042634 [Homo sapiens]
Length = 198
Score = 420 bits (1079), Expect = e-118
Identities = 197/198 (99%), Positives = 197/198 (99%)
Query: 1 MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRD 60
MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWS ASALTFTRD
Sbjct: 1 MGSDLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRD 60
Query: 61 FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK 120
FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK
Sbjct: 61 FESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSK 120
Query: 121 HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV 180
HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV
Sbjct: 121 HWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSV 180
Query: 181 DAGYPKIIDDLPGISKKN 198
DAGYPKIIDDLPGISKKN
Sbjct: 181 DAGYPKIIDDLPGISKKN 198
>gi|169203154 PREDICTED: similar to hCG2042634 [Homo sapiens]
Length = 358
Score = 365 bits (938), Expect = e-101
Identities = 172/174 (98%), Positives = 173/174 (99%)
Query: 25 EDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFY 84
+DQNYMPNLPQEDVDRATGKAFELWS ASALTFTRDFESEGDIILSFVFLADLHDNSPFY
Sbjct: 185 KDQNYMPNLPQEDVDRATGKAFELWSNASALTFTRDFESEGDIILSFVFLADLHDNSPFY 244
Query: 85 GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP 144
GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP
Sbjct: 245 GHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFP 304
Query: 145 ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 198
ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN
Sbjct: 305 ERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGISKKN 358
Score = 59.3 bits (142), Expect = 2e-09
Identities = 25/25 (100%), Positives = 25/25 (100%)
Query: 1 MGSDLRVYNTVFSPDDWRGIQKWQE 25
MGSDLRVYNTVFSPDDWRGIQKWQE
Sbjct: 1 MGSDLRVYNTVFSPDDWRGIQKWQE 25
>gi|225543094 matrix metalloproteinase 1 isoform 2 [Homo sapiens]
Length = 403
Score = 113 bits (282), Expect = 1e-25
Identities = 54/92 (58%), Positives = 68/92 (73%), Gaps = 3/92 (3%)
Query: 107 DNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 166
D DE R F+ +K+W VQ +L GYP+D+YSSF FP VK IDAA+ E++TGKT+FFV
Sbjct: 270 DRDEVRF--FKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFV 327
Query: 167 ANEYWRYDENMQSVDAGYPKII-DDLPGISKK 197
AN+YWRYDE +S+D GYPK+I D PGI K
Sbjct: 328 ANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHK 359
Score = 110 bits (276), Expect = 6e-25
Identities = 56/105 (53%), Positives = 69/105 (65%), Gaps = 7/105 (6%)
Query: 19 GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFV 72
G +W++ +NY P+LP+ DVD A KAF+LWS + LTFT+ E + DI++SFV
Sbjct: 39 GNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFV 98
Query: 73 FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFR 117
D DNSPF G G LAHAF PGPGIGGD HFD DE T +FR
Sbjct: 99 -RGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFR 142
>gi|4505215 matrix metalloproteinase 1 isoform 1 preproprotein [Homo
sapiens]
Length = 469
Score = 113 bits (282), Expect = 1e-25
Identities = 54/92 (58%), Positives = 68/92 (73%), Gaps = 3/92 (3%)
Query: 107 DNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 166
D DE R F+ +K+W VQ +L GYP+D+YSSF FP VK IDAA+ E++TGKT+FFV
Sbjct: 336 DRDEVRF--FKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFV 393
Query: 167 ANEYWRYDENMQSVDAGYPKII-DDLPGISKK 197
AN+YWRYDE +S+D GYPK+I D PGI K
Sbjct: 394 ANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHK 425
Score = 110 bits (276), Expect = 6e-25
Identities = 56/105 (53%), Positives = 69/105 (65%), Gaps = 7/105 (6%)
Query: 19 GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFV 72
G +W++ +NY P+LP+ DVD A KAF+LWS + LTFT+ E + DI++SFV
Sbjct: 105 GNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFV 164
Query: 73 FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFR 117
D DNSPF G G LAHAF PGPGIGGD HFD DE T +FR
Sbjct: 165 -RGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFR 208
>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
Length = 467
Score = 95.9 bits (237), Expect = 2e-20
Identities = 52/101 (51%), Positives = 63/101 (62%), Gaps = 7/101 (6%)
Query: 19 GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFV 72
G KW+ +NY P L + +V+RA AFELWS AS L FTR + E DI ++F
Sbjct: 104 GNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAF- 162
Query: 73 FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
+ D DNSPF G +G LAHAF PG GIGGD HFD +ET T
Sbjct: 163 YQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWT 203
Score = 72.8 bits (177), Expect = 2e-13
Identities = 34/83 (40%), Positives = 54/83 (65%), Gaps = 4/83 (4%)
Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
F+ +++W + +L GYP+D+ S++ FP V+ IDAA++ + KT+FFV +++WRYD
Sbjct: 344 FKGNQYWALSGYDILQGYPKDI-SNYGFPSSVQAIDAAVFYRS--KTYFFVNDQFWRYDN 400
Query: 176 NMQSVDAGYPKIIDD-LPGISKK 197
Q ++ GYPK I PGI K
Sbjct: 401 QRQFMEPGYPKSISGAFPGIESK 423
>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
Length = 477
Score = 95.5 bits (236), Expect = 3e-20
Identities = 49/117 (41%), Positives = 71/117 (60%), Gaps = 7/117 (5%)
Query: 19 GIQKWQEDQ------NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFV 72
GI KW++ NY P+LP++ VD A KA ++W + + LTF+R +E E DI++SF
Sbjct: 105 GIPKWRKTHLTYRIVNYTPDLPKDAVDSAVEKALKVWEEVTPLTFSRLYEGEADIMISFA 164
Query: 73 FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQL 129
+ + D PF G LAHA+ PGPGI GD HFD+DE TKD + ++V ++
Sbjct: 165 -VREHGDFYPFDGPGNVLAHAYAPGPGINGDAHFDDDEQWTKDTTGTNLFLVAAHEI 220
Score = 83.6 bits (205), Expect = 1e-16
Identities = 44/113 (38%), Positives = 70/113 (61%), Gaps = 9/113 (7%)
Query: 90 LAHAFPPGPGIGGDVHFDNDETRTKD----FRSSKHWVVQEDQLLSGYPRDVYSSFVFPE 145
L +F P G D + E +KD F+ ++ W ++ +++ +GYPR +++ FP
Sbjct: 328 LISSFWPSLPSGVDAAY---EVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHT-LGFPP 383
Query: 146 RVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK-IIDDLPGISKK 197
V+KIDAAI +K+ KT+FFV ++YWR+DE S++ G+PK I +D PGI K
Sbjct: 384 TVRKIDAAISDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSK 436
>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
Length = 476
Score = 94.7 bits (234), Expect = 4e-20
Identities = 48/120 (40%), Positives = 74/120 (61%), Gaps = 13/120 (10%)
Query: 19 GIQKWQEDQ------NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFV 72
G+ KW++ NY P+LP++ VD A KA ++W + + LTF+R +E E DI++SF
Sbjct: 104 GMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFA 163
Query: 73 FLADLHDNSPFYGHDG---CLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQL 129
+ ++ FY DG LAHA+PPGPG+ GD+HFD+DE T+D + ++V +L
Sbjct: 164 ----VKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHEL 219
Score = 86.7 bits (213), Expect = 1e-17
Identities = 35/83 (42%), Positives = 62/83 (74%), Gaps = 2/83 (2%)
Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
F+ ++ W ++ +++ +GYPR +++ FP ++KIDAA+ +K+ KT+FF A++YWR+DE
Sbjct: 354 FKGNEFWAIRGNEVQAGYPRGIHT-LGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDE 412
Query: 176 NMQSVDAGYPKII-DDLPGISKK 197
N QS++ G+P++I DD PG+ K
Sbjct: 413 NSQSMEQGFPRLIADDFPGVEPK 435
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 94.0 bits (232), Expect = 8e-20
Identities = 45/84 (53%), Positives = 57/84 (67%), Gaps = 1/84 (1%)
Query: 27 QNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFYGH 86
QNY +LP+ +D A +AF LWS + LTFTR + + DI++ F +A+ D PF G
Sbjct: 126 QNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFG-VAEHGDGYPFDGK 184
Query: 87 DGCLAHAFPPGPGIGGDVHFDNDE 110
DG LAHAFPPGPGI GD HFD+DE
Sbjct: 185 DGLLAHAFPPGPGIQGDAHFDDDE 208
>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
Length = 471
Score = 88.6 bits (218), Expect = 3e-18
Identities = 61/185 (32%), Positives = 92/185 (49%), Gaps = 22/185 (11%)
Query: 4 DLRVYNTVFSPDDWRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFES 63
D+ YN W + NY P++ +V++A KAF++WS + L FTR +
Sbjct: 100 DVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDG 159
Query: 64 EGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWV 123
DI++SF + + D PF G G LAHAFPPGP GGD HFD+DET T + ++
Sbjct: 160 IADIMISFG-IKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFL 218
Query: 124 VQEDQ----LLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQS 179
V + L + +D + +FP IY TGK+HF + D+++Q
Sbjct: 219 VAAHEFGHSLGLDHSKDP-GALMFP---------IYTY-TGKSHFMLP------DDDVQG 261
Query: 180 VDAGY 184
+ + Y
Sbjct: 262 IQSLY 266
Score = 75.1 bits (183), Expect = 4e-14
Identities = 36/83 (43%), Positives = 50/83 (60%), Gaps = 2/83 (2%)
Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
FR K W + +L GYP+ + S P+ VKKI AA++ +DTGKT F N+ WRYD+
Sbjct: 349 FRGRKFWALNGYDILEGYPKKI-SELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDD 407
Query: 176 NMQSVDAGYPKII-DDLPGISKK 197
+D YP++I +D PGI K
Sbjct: 408 TNHIMDKDYPRLIEEDFPGIGDK 430
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 84.7 bits (208), Expect = 5e-17
Identities = 55/154 (35%), Positives = 79/154 (51%), Gaps = 23/154 (14%)
Query: 22 KWQEDQ------NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLA 75
KW ++Q Y P+L E VD A +AF++WS + L F+R + E DI+++F
Sbjct: 68 KWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINF-GRW 126
Query: 76 DLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLS---G 132
+ D PF G DG LAHAF PG G+GGD HFD+DE W + E Q++ G
Sbjct: 127 EHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDEL----------WTLGEGQVVRVKYG 176
Query: 133 YPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 166
Y F F K+ ++ DTG++ F+
Sbjct: 177 NADGEYCKFPFLFNGKEYNSC---TDTGRSDGFL 207
Score = 58.2 bits (139), Expect = 5e-09
Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 110 ETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANE 169
E + F +++W+ L GYP+ + +S P V+++DAA KT+ F ++
Sbjct: 479 EEKAVFFAGNEYWIYSASTLERGYPKPL-TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 537
Query: 170 YWRYDENMQSVDAGYPKIIDD 190
+WRY+E + +D G+PK+I D
Sbjct: 538 FWRYNEVKKKMDPGFPKLIAD 558
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 143 FPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDL 191
+PE +KIDA K FF NEYW Y + +++ GYPK + L
Sbjct: 463 WPELPEKIDAVYEAPQEEKAVFFAGNEYWIY--SASTLERGYPKPLTSL 509
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 84.7 bits (208), Expect = 5e-17
Identities = 55/154 (35%), Positives = 79/154 (51%), Gaps = 23/154 (14%)
Query: 22 KWQEDQ------NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLA 75
KW ++Q Y P+L E VD A +AF++WS + L F+R + E DI+++F
Sbjct: 118 KWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINF-GRW 176
Query: 76 DLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQLLS---G 132
+ D PF G DG LAHAF PG G+GGD HFD+DE W + E Q++ G
Sbjct: 177 EHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDEL----------WTLGEGQVVRVKYG 226
Query: 133 YPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFV 166
Y F F K+ ++ DTG++ F+
Sbjct: 227 NADGEYCKFPFLFNGKEYNSC---TDTGRSDGFL 257
Score = 58.2 bits (139), Expect = 5e-09
Identities = 26/81 (32%), Positives = 46/81 (56%), Gaps = 1/81 (1%)
Query: 110 ETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANE 169
E + F +++W+ L GYP+ + +S P V+++DAA KT+ F ++
Sbjct: 529 EEKAVFFAGNEYWIYSASTLERGYPKPL-TSLGLPPDVQRVDAAFNWSKNKKTYIFAGDK 587
Query: 170 YWRYDENMQSVDAGYPKIIDD 190
+WRY+E + +D G+PK+I D
Sbjct: 588 FWRYNEVKKKMDPGFPKLIAD 608
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 143 FPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDL 191
+PE +KIDA K FF NEYW Y + +++ GYPK + L
Sbjct: 513 WPELPEKIDAVYEAPQEEKAVFFAGNEYWIY--SASTLERGYPKPLTSL 559
>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
Length = 513
Score = 81.6 bits (200), Expect = 4e-16
Identities = 43/101 (42%), Positives = 56/101 (55%), Gaps = 4/101 (3%)
Query: 17 WRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLAD 76
WR NY P++ + VD A + E+WSK + L FT+ + DI+++F
Sbjct: 106 WRKYNLTYRIINYTPDMARAAVDEAIQEGLEVWSKVTPLKFTKISKGIADIMIAF--RTR 163
Query: 77 LHDNSPFY--GHDGCLAHAFPPGPGIGGDVHFDNDETRTKD 115
+H P Y G G L HAFPPGPG+GGD HFD DE TKD
Sbjct: 164 VHGRCPRYFDGPLGVLGHAFPPGPGLGGDTHFDEDENWTKD 204
Score = 74.3 bits (181), Expect = 6e-14
Identities = 37/101 (36%), Positives = 61/101 (60%), Gaps = 4/101 (3%)
Query: 98 PGIGGDVH--FDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIY 155
P + D+ ++N + F+ W+++ +L YP+ +++ FP RVKKIDAA+
Sbjct: 323 PSLPADLQAAYENPRDKILVFKDENFWMIRGYAVLPDYPKSIHT-LGFPGRVKKIDAAVC 381
Query: 156 EKDTGKTHFFVANEYWRYDENMQSVDAGYP-KIIDDLPGIS 195
+K T KT+FFV WR+DE Q++D G+P +++ PGIS
Sbjct: 382 DKTTRKTYFFVGIWCWRFDEMTQTMDKGFPQRVVKHFPGIS 422
>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
sapiens]
Length = 483
Score = 77.8 bits (190), Expect = 6e-15
Identities = 43/101 (42%), Positives = 56/101 (55%), Gaps = 7/101 (6%)
Query: 19 GIQKWQED------QNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFV 72
G KW+++ Y P++ +VD+A A + WS A L+F R E DI++SF
Sbjct: 113 GEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFE 172
Query: 73 FLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
D D+ PF G G LAHAF PG G+GGD HFDN E T
Sbjct: 173 N-GDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWT 212
Score = 62.0 bits (149), Expect = 3e-10
Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Query: 103 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKT 162
D ++ E T F H+ + + G PR +Y F FP V++IDAA+Y ++ KT
Sbjct: 348 DAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYD-FGFPRHVQQIDAAVYLREPQKT 406
Query: 163 HFFVANEYWRYDENMQSVDAGYPK 186
FFV +EY+ YDE + ++ YPK
Sbjct: 407 LFFVGDEYYSYDERKRKMEKDYPK 430
Score = 27.7 bits (60), Expect = 6.7
Identities = 13/38 (34%), Positives = 19/38 (50%), Gaps = 2/38 (5%)
Query: 134 PRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYW 171
P + SSF P+ + +DAA + G +FF YW
Sbjct: 333 PSTITSSF--PQLMSNVDAAYEVAERGTAYFFKGPHYW 368
>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
Length = 645
Score = 77.8 bits (190), Expect = 6e-15
Identities = 44/107 (41%), Positives = 60/107 (56%), Gaps = 16/107 (14%)
Query: 21 QKWQEDQ------NYMPNLPQEDVDRATGKAFELWSKASALTFT-------RDFESEGDI 67
QKW++ NY P + + D +A +AF++W K + LTF + E DI
Sbjct: 161 QKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADI 220
Query: 68 ILSFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
++ F + H D+SPF G G LAHA+ PGPGIGGD HFD+DE T
Sbjct: 221 MIFFA--SGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT 265
Score = 58.2 bits (139), Expect = 5e-09
Identities = 32/92 (34%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 103 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKT 162
D ++ + R F+ K+WV +E + GYP + R + ID A+ + GKT
Sbjct: 430 DAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPR-EGIDTALRWEPVGKT 488
Query: 163 HFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 194
+FF YWRY E ++ D GYPK I GI
Sbjct: 489 YFFKGERYWRYSEERRATDPGYPKPITVWKGI 520
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/89 (26%), Positives = 46/89 (51%), Gaps = 6/89 (6%)
Query: 112 RTKDFRSSKHWVVQEDQLLS--GYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANE 169
+T F+ ++W E++ + GYP+ + P+ + A K+ T+F+ +
Sbjct: 487 KTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQ---GAFISKEGYYTYFYKGRD 543
Query: 170 YWRYDENMQSVDAGYPK-IIDDLPGISKK 197
YW++D SV+ GYP+ I+ D G ++K
Sbjct: 544 YWKFDNQKLSVEPGYPRNILRDWMGCNQK 572
>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
sapiens]
Length = 470
Score = 77.4 bits (189), Expect = 7e-15
Identities = 37/83 (44%), Positives = 53/83 (63%), Gaps = 2/83 (2%)
Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
F+ K+W++ + YP+ ++S F FP VKKIDAA++ +T+FFV N+YWRYDE
Sbjct: 347 FKDDKYWLISNLRPEPNYPKSIHS-FGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDE 405
Query: 176 NMQSVDAGYPKII-DDLPGISKK 197
Q +D GYPK+I + GI K
Sbjct: 406 RRQMMDPGYPKLITKNFQGIGPK 428
Score = 77.0 bits (188), Expect = 1e-14
Identities = 43/95 (45%), Positives = 53/95 (55%), Gaps = 3/95 (3%)
Query: 17 WRGIQKWQEDQNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLAD 76
WR NY P++ +EDVD A KAF++WS + L F++ DI++ VF
Sbjct: 109 WRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILV--VFARG 166
Query: 77 LH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDE 110
H D F G G LAHAF PG GIGGD HFD DE
Sbjct: 167 AHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDE 201
>gi|149999365 matrix metalloproteinase 16 isoform 2 preproprotein
[Homo sapiens]
Length = 457
Score = 76.3 bits (186), Expect = 2e-14
Identities = 42/105 (40%), Positives = 58/105 (55%), Gaps = 12/105 (11%)
Query: 21 QKWQED------QNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESE-----GDIIL 69
QKWQ +N P + + +A +AF++W + LTF SE D+ +
Sbjct: 125 QKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDI 184
Query: 70 SFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
+ +F + H D+SPF G G LAHA+ PGPGIGGD HFD+DE T
Sbjct: 185 TIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT 229
>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
[Homo sapiens]
Length = 607
Score = 76.3 bits (186), Expect = 2e-14
Identities = 42/105 (40%), Positives = 58/105 (55%), Gaps = 12/105 (11%)
Query: 21 QKWQED------QNYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESE-----GDIIL 69
QKWQ +N P + + +A +AF++W + LTF SE D+ +
Sbjct: 125 QKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEEVPYSELENGKRDVDI 184
Query: 70 SFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
+ +F + H D+SPF G G LAHA+ PGPGIGGD HFD+DE T
Sbjct: 185 TIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWT 229
Score = 72.0 bits (175), Expect = 3e-13
Identities = 37/94 (39%), Positives = 56/94 (59%), Gaps = 5/94 (5%)
Query: 103 DVHFDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYS--SFVFPERVKKIDAAIYEKDTG 160
D ++N + F+ +K+WV ++ L GYP D+ + S + P ID+AI+ +D G
Sbjct: 393 DAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHG---IDSAIWWEDVG 449
Query: 161 KTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 194
KT+FF + YWRY E M+++D GYPK I GI
Sbjct: 450 KTYFFKGDRYWRYSEEMKTMDPGYPKPITVWKGI 483
Score = 49.7 bits (117), Expect = 2e-06
Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Query: 82 PFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQ--LLSGYPRDVYS 139
P Y HD + P GI + ++ D +T F+ ++W E+ + GYP+ +
Sbjct: 421 PGYPHDLITLGSGIPPHGIDSAIWWE-DVGKTYFFKGDRYWRYSEEMKTMDPGYPKPITV 479
Query: 140 SFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK-IIDDLPG 193
PE + A K+ G T+F+ EYW+++ + V+ GYP+ I+ D G
Sbjct: 480 WKGIPESPQ---GAFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSILKDFMG 531
>gi|4505219 matrix metalloproteinase 7 preproprotein [Homo sapiens]
Length = 267
Score = 67.8 bits (164), Expect = 6e-12
Identities = 37/86 (43%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Query: 28 NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87
+Y +LP VDR KA +W K L F + DI++ F A D+ PF G
Sbjct: 115 SYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAH-GDSYPFDGPG 173
Query: 88 GCLAHAFPPGPGIGGDVHFDNDETRT 113
LAHAF PG G+GGD HFD DE T
Sbjct: 174 NTLAHAFAPGTGLGGDAHFDEDERWT 199
>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
Length = 582
Score = 67.0 bits (162), Expect = 1e-11
Identities = 44/126 (34%), Positives = 61/126 (48%), Gaps = 20/126 (15%)
Query: 22 KWQED------QNYMPNLPQEDVDRATGKAFELWSKASALTFTR--------DFESEGDI 67
KWQ + QNY P + + A KAF +W A+ L F E + DI
Sbjct: 118 KWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLRFREVPYAYIREGHEKQADI 177
Query: 68 ILSFVFLADLH-DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDE---TRTKDFRSSKHWV 123
++ F H D++PF G G LAHA+ PGP IGGD HFD+ E R +D + ++
Sbjct: 178 MIFFA--EGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSAEPWTVRNEDLNGNDIFL 235
Query: 124 VQEDQL 129
V +L
Sbjct: 236 VAVHEL 241
Score = 63.2 bits (152), Expect = 1e-10
Identities = 32/79 (40%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
F+ KHWV E L GYP+ + KIDAA++ GKT+FF N+Y+R++E
Sbjct: 382 FKGDKHWVFDEASLEPGYPKHI-KELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNE 440
Query: 176 NMQSVDAGYPKIIDDLPGI 194
+++VD+ YPK I GI
Sbjct: 441 ELRAVDSEYPKNIKVWEGI 459
Score = 42.4 bits (98), Expect = 3e-04
Identities = 25/79 (31%), Positives = 43/79 (54%), Gaps = 11/79 (13%)
Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAI---YEKDTGKTHFFVANEYWR 172
F+ W V+ +Q++ GYP + + + + A+I YE+ GK FF +++W
Sbjct: 336 FKERWFWRVRNNQVMDGYPMPIGQFW------RGLPASINTAYERKDGKFVFFKGDKHWV 389
Query: 173 YDENMQSVDAGYPKIIDDL 191
+DE S++ GYPK I +L
Sbjct: 390 FDE--ASLEPGYPKHIKEL 406
>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
Length = 669
Score = 64.3 bits (155), Expect = 6e-11
Identities = 39/96 (40%), Positives = 51/96 (53%), Gaps = 11/96 (11%)
Query: 27 QNYMPNLPQEDVDRATGKAFELWSKASALTFTR--------DFESEGDIILSFVFLADLH 78
QNY L A +AF +W +A+ L F + E DI++ +F + H
Sbjct: 149 QNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMV--LFASGFH 206
Query: 79 -DNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRT 113
D+SPF G G LAHA+ PGPG+GGD HFD DE T
Sbjct: 207 GDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWT 242
Score = 63.2 bits (152), Expect = 1e-10
Identities = 34/98 (34%), Positives = 54/98 (55%), Gaps = 3/98 (3%)
Query: 99 GIGGDVH--FDNDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYE 156
G+ GD+ ++ + R F+ ++W+ +E L GYP+ + +S+ +ID AI+
Sbjct: 414 GLPGDISAAYERQDGRFVFFKGDRYWLFREANLEPGYPQPL-TSYGLGIPYDRIDTAIWW 472
Query: 157 KDTGKTHFFVANEYWRYDENMQSVDAGYPKIIDDLPGI 194
+ TG T FF + YWR++E Q D GYPK I GI
Sbjct: 473 EPTGHTFFFQEDRYWRFNEETQRGDPGYPKPISVWQGI 510
Score = 38.5 bits (88), Expect = 0.004
Identities = 20/75 (26%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 116 FRSSKHWVVQEDQLLS--GYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRY 173
F+ ++W E+ GYP+ + P K A D T+F+ +YW++
Sbjct: 481 FQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPK---GAFLSNDAAYTYFYKGTKYWKF 537
Query: 174 DENMQSVDAGYPKII 188
D ++ GYPK I
Sbjct: 538 DNERLRMEPGYPKSI 552
>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
sapiens]
Length = 488
Score = 62.0 bits (149), Expect = 3e-10
Identities = 38/96 (39%), Positives = 48/96 (50%), Gaps = 11/96 (11%)
Query: 33 LPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDGCLAH 92
L QE V + +A ++WS + LTFT E DI++ F D+ PF G G LAH
Sbjct: 121 LVQEQVRQTMAEALKVWSDVTPLTFTEVHEGRADIMIDFARYWH-GDDLPFDGPGGILAH 179
Query: 93 AFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQEDQ 128
AF P GDVHFD DET W + +DQ
Sbjct: 180 AFFPKTHREGDVHFDYDET----------WTIGDDQ 205
Score = 37.7 bits (86), Expect = 0.006
Identities = 48/199 (24%), Positives = 75/199 (37%), Gaps = 19/199 (9%)
Query: 8 YNTVFSPDDWRGIQK-----WQEDQNYMPNL-PQEDVDRATGKAFELWSKASALTFTRDF 61
Y SPDD RG+Q W + P L PQ +D E + A + D
Sbjct: 241 YPLSLSPDDCRGVQHLYGQPWPTVTSRTPALGPQAGIDTNEIAPLEPDAPPDACEASFDA 300
Query: 62 ES--EGDIIL---SFVFLADLHDNSPFYGHDGCLAHAFPPGPGIGGDVHFDNDETRTKDF 116
S G++ FV+ P Y LA G D F++ + F
Sbjct: 301 VSTIRGELFFFKAGFVWRLRGGQLQPGYP---ALASRHWQGLPSPVDAAFEDAQGHIWFF 357
Query: 117 RSSKHWVVQ-EDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
+ +++WV E +L P FP A ++ + K +FF +YWR+
Sbjct: 358 QGAQYWVYDGEKPVLGPAPLTELGLVRFPVHA----ALVWGPEKNKIYFFRGRDYWRFHP 413
Query: 176 NMQSVDAGYPKIIDDLPGI 194
+ + VD+ P+ D G+
Sbjct: 414 STRRVDSPVPRRATDWRGV 432
Score = 27.3 bits (59), Expect = 8.7
Identities = 12/40 (30%), Positives = 21/40 (52%), Gaps = 1/40 (2%)
Query: 149 KIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPKII 188
+IDAA + D G +F YW++D G+P+++
Sbjct: 435 EIDAAFQDAD-GYAYFLRGRLYWKFDPVKVKALEGFPRLV 473
>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
sapiens]
Length = 603
Score = 55.1 bits (131), Expect = 4e-08
Identities = 33/93 (35%), Positives = 49/93 (52%), Gaps = 11/93 (11%)
Query: 101 GGDVHFDNDET---RTKD-----FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDA 152
G +H D+ + RT D F+ ++WV +++ + GYPR V S F P IDA
Sbjct: 377 GLPLHLDSVDAVYERTSDHKIVFFKGDRYWVFKDNNVEEGYPRPV-SDFSLPPG--GIDA 433
Query: 153 AIYEKDTGKTHFFVANEYWRYDENMQSVDAGYP 185
A +T+FF YWRYD++ + +D GYP
Sbjct: 434 AFSWAHNDRTYFFKDQLYWRYDDHTRHMDPGYP 466
Score = 50.4 bits (119), Expect = 1e-06
Identities = 34/76 (44%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 45 AFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHDGCLAHAFPPG-PGIGGD 103
A ++WS + L F S DI + F AD +D PF G G +AHAF PG GD
Sbjct: 163 ALKVWSDIAPLNFHEVAGSAADIQIDFS-KADHNDGYPFDGPGGTVAHAFFPGHHHTAGD 221
Query: 104 VHFDNDETRTKDFRSS 119
HFD+DE T FRSS
Sbjct: 222 THFDDDEAWT--FRSS 235
Score = 29.3 bits (64), Expect = 2.3
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 8/96 (8%)
Query: 93 AFPPGPGIGGDVHFDNDETRTKDFRSSKHWVVQED--QLLSGYPRDVYSSFVFPERVKKI 150
+ PPG GI + +++ RT F+ +W + + GYP S ++ +
Sbjct: 425 SLPPG-GIDAAFSWAHND-RTYFFKDQLYWRYDDHTRHMDPGYPAQ---SPLWRGVPSTL 479
Query: 151 DAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK 186
D A+ D G ++FF EYW+ + V GYP+
Sbjct: 480 DDAMRWSD-GASYFFRGQEYWKVLDGELEVAPGYPQ 514
>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
sapiens]
Length = 562
Score = 50.1 bits (118), Expect = 1e-06
Identities = 36/85 (42%), Positives = 42/85 (49%), Gaps = 5/85 (5%)
Query: 33 LPQEDVDRATGKAFELWSKASALTFTRDFESEG---DIILSFVFLADLHDNSPFYGHDGC 89
L QE V A W S LTF +G DI++ F A D+ PF G G
Sbjct: 133 LSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFA-RAFHQDSYPFDGLGGT 191
Query: 90 LAHAFPPGP-GIGGDVHFDNDETRT 113
LAHAF PG I GD HFD++ET T
Sbjct: 192 LAHAFFPGEHPISGDTHFDDEETWT 216
Score = 41.2 bits (95), Expect = 6e-04
Identities = 24/71 (33%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDE 175
F + WV Q+ QL G R + + P +++DA GKT+ +YWRYDE
Sbjct: 385 FSGPQFWVFQDRQLEGG-ARPLTELGLPPG--EEVDAVFSWPQNGKTYLVRGRQYWRYDE 441
Query: 176 NMQSVDAGYPK 186
D GYP+
Sbjct: 442 AAARPDPGYPR 452
Score = 28.1 bits (61), Expect = 5.1
Identities = 15/55 (27%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 132 GYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK 186
GYPRD+ P + + + G T+FF YWR+ +N + P+
Sbjct: 449 GYPRDLSLWEGAPPSPDDVTVS----NAGDTYFFKGAHYWRFPKNSIKTEPDAPQ 499
>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
[Homo sapiens]
Length = 520
Score = 49.3 bits (116), Expect = 2e-06
Identities = 36/86 (41%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
Query: 28 NYMPNLPQEDVDRATGKAFELWSKASALTF-TRDFESEGDIILSFVFLADLHD--NSPFY 84
N+ +LP+ V A AF+LWS SAL F DI L+F F D +D + F
Sbjct: 141 NWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTF-FQGDHNDGLGNAFD 199
Query: 85 GHDGCLAHAFPPGPGIGGDVHFDNDE 110
G G LAHAF P G+ HFD DE
Sbjct: 200 GPGGALAHAFLPR---RGEAHFDQDE 222
>gi|73808266 matrix metalloproteinase 26 preproprotein [Homo
sapiens]
Length = 261
Score = 47.8 bits (112), Expect = 6e-06
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 28 NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87
NY ++ V + A +WS + L F + + DI +SF A D PF G
Sbjct: 110 NYPHDMKPSAVKDSIYNAVSIWSNVTPLIFQQVQNGDADIKVSFWQWAH-EDGWPFDGPG 168
Query: 88 GCLAHAFPPGPGIGGDVHFDNDE 110
G L HAF P G G VHFD +E
Sbjct: 169 GILGHAFLPNSGNPGVVHFDKNE 191
>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
[Homo sapiens]
Length = 508
Score = 41.6 bits (96), Expect = 4e-04
Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 28 NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFESEGDIILSFVFLADLHDNSPFYGHD 87
N LP A +AF+ WS + LTF DI LSF + ++ F G
Sbjct: 115 NLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPG 174
Query: 88 GCLAHAFPPGPGIGGDVHFDNDETRTK 114
LAHA P G VHFD DE T+
Sbjct: 175 RVLAHADIPEL---GSVHFDEDEFWTE 198
Score = 34.7 bits (78), Expect = 0.054
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 8/77 (10%)
Query: 116 FRSSKHWVVQEDQLLSGYPRDVYSSFVFPERVK-KIDAAIYEKDTGKTHFFVANEYWRYD 174
F+ K W ++ G+P+ + RV+ +DAA+Y K F + YW++D
Sbjct: 352 FKGDKVWRYINFKMSPGFPKKL-------NRVEPNLDAALYWPLNQKVFLFKGSGYWQWD 404
Query: 175 ENMQSVDAGYPKIIDDL 191
E ++ + YPK I L
Sbjct: 405 ELARTDFSSYPKPIKGL 421
Score = 34.3 bits (77), Expect = 0.071
Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 10/77 (12%)
Query: 116 FRSSKHWVVQEDQL----LSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYW 171
F+ S +W Q D+L S YP+ + F V +A G+ +FF YW
Sbjct: 395 FKGSGYW--QWDELARTDFSSYPKPIKGLFT---GVPNQPSAAMSWQDGRVYFFKGKVYW 449
Query: 172 RYDENMQSVDAGYPKII 188
R ++ ++ V+ GYP+ I
Sbjct: 450 RLNQQLR-VEKGYPRNI 465
Score = 30.8 bits (68), Expect = 0.79
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 150 IDAAIYEKDTGKTHFFVANEYWRYDENMQSVDAGYPK 186
+DAA+Y T HFF ++ WRY S G+PK
Sbjct: 337 LDAAVYSPRTQWIHFFKGDKVWRYINFKMS--PGFPK 371
>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
sapiens]
Length = 569
Score = 35.8 bits (81), Expect = 0.024
Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 8/77 (10%)
Query: 37 DVDRATGKAFELWSKASALTFTRDFESEG---DIILSFVFLADLHDNSPFYGHDGCLAHA 93
D R AF +WS+ + L F D + G DI L F L F G AHA
Sbjct: 193 DQRRIVALAFRMWSEVTPLDFREDLAAPGAAVDIKLGFGRGRHLGCPRAFDGSGQEFAHA 252
Query: 94 FPPGPGIGGDVHFDNDE 110
+ G D+HFD+DE
Sbjct: 253 WRLG-----DIHFDDDE 264
Score = 34.7 bits (78), Expect = 0.054
Identities = 44/201 (21%), Positives = 81/201 (40%), Gaps = 34/201 (16%)
Query: 28 NYMPNLPQEDVDRATGKAFELWSKASALTFTRDFE-------SEGDIILSF--------- 71
NY+P P ++D + KA + + +F F+ G++++ F
Sbjct: 304 NYIPQEPAFELDWSDRKAIQKLYGSCEGSFDTAFDWIRKERNQYGEVMVRFSTYFFRNSW 363
Query: 72 VFLADLHDNSPFYGHDGCLAHAFP--PGPGIGGDVH---FDNDETRTKDFRSSKHW---- 122
+L + +N YG + +P P I VH + DE F+ +++W
Sbjct: 364 YWLYENRNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDERYF--FQGNQYWRYDS 421
Query: 123 ----VVQEDQLLSGYPRDVYSSFVFPERVKKIDAAIYEKDTGKTHFFVANEYWRYDENMQ 178
+ ED+ YP+ + F P +D A Y++ +FF + + +D N
Sbjct: 422 DKDQALTEDEQGKSYPKLISEGF--PGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRN 479
Query: 179 SVDAGYPKIIDDL-PGISKKN 198
V YPK I ++ P + +N
Sbjct: 480 RVLNSYPKRITEVFPAVIPQN 500
Score = 31.2 bits (69), Expect = 0.60
Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 6/89 (6%)
Query: 90 LAHAFPPGPGIGGDVHFDNDETRTKDFRSSKHWV--VQEDQLLSGYPRDVYSSF--VFPE 145
++ FP P +D + F+ S + V +++L+ YP+ + F V P+
Sbjct: 440 ISEGFPGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRNRVLNSYPKRITEVFPAVIPQ 499
Query: 146 R--VKKIDAAIYEKDTGKTHFFVANEYWR 172
+ ID+A Y FF N YW+
Sbjct: 500 NHPFRNIDSAYYSYAYNSIFFFKGNAYWK 528
>gi|88853069 vitronectin precursor [Homo sapiens]
Length = 478
Score = 35.0 bits (79), Expect = 0.042
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 12/79 (15%)
Query: 116 FRSSKHWVVQEDQLLSGYP---RDVYSSFVFPERVKKIDAAIYEKDT-GKTHFFVANEYW 171
FR + + E + GYP RDV+ IDAA + GKT+ F ++YW
Sbjct: 175 FRGQYCYELDEKAVRPGYPKLIRDVWGI------EGPIDAAFTRINCQGKTYLFKGSQYW 228
Query: 172 RYDENMQSVDAGYPKIIDD 190
R+++ + +D YP+ I D
Sbjct: 229 RFEDGV--LDPDYPRNISD 245
Score = 32.7 bits (73), Expect = 0.21
Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 3/69 (4%)
Query: 108 NDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSF-VFPERVKKIDAAIYEKDTG--KTHF 164
N + +T F+ S++W ++ L YPR++ F P+ V A +G + +F
Sbjct: 214 NCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYF 273
Query: 165 FVANEYWRY 173
F +YW Y
Sbjct: 274 FKGKQYWEY 282
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 34.3 bits (77), Expect = 0.071
Identities = 15/29 (51%), Positives = 21/29 (72%), Gaps = 2/29 (6%)
Query: 160 GKTHFFVANEYWRYDENMQSVDAGYPKII 188
GKT FF ++YWR+ +++ DAGYPK I
Sbjct: 1072 GKTFFFKDSQYWRFTNDIK--DAGYPKPI 1098
Score = 28.5 bits (62), Expect = 3.9
Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 2/60 (3%)
Query: 108 NDETRTKDFRSSKHWVVQEDQLLSGYPRDVYSSF--VFPERVKKIDAAIYEKDTGKTHFF 165
N E +T F+ S++W D +GYP+ ++ F + + V + A Y+ +FF
Sbjct: 1069 NCEGKTFFFKDSQYWRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYKNWPESVYFF 1128
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.138 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,695,872
Number of Sequences: 37866
Number of extensions: 391424
Number of successful extensions: 874
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 743
Number of HSP's gapped (non-prelim): 92
length of query: 198
length of database: 18,247,518
effective HSP length: 97
effective length of query: 101
effective length of database: 14,574,516
effective search space: 1472026116
effective search space used: 1472026116
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.