Guide to the Human Genome
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Search of human proteins with 169173078

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169173078 PREDICTED: hypothetical protein [Homo sapiens]
         (402 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169173078 PREDICTED: hypothetical protein [Homo sapiens]           827   0.0  
gi|169172508 PREDICTED: hypothetical protein [Homo sapiens]           825   0.0  
gi|169173306 PREDICTED: hypothetical protein [Homo sapiens]           383   e-106
gi|239749426 PREDICTED: hypothetical protein XP_002347042 [Homo ...   154   2e-37
gi|239743560 PREDICTED: hypothetical protein XP_002342893 [Homo ...   154   2e-37
gi|239754887 PREDICTED: hypothetical protein XP_002346152 [Homo ...   153   2e-37
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               49   8e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   8e-06
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    49   1e-05
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    49   1e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    48   2e-05
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 48   2e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      47   3e-05
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    47   3e-05
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    47   4e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    47   4e-05
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    46   7e-05
gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]            45   9e-05
gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]            45   9e-05
gi|13129104 coiled-coil domain containing 86 [Homo sapiens]            45   1e-04
gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo ...    45   2e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   2e-04
gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I...    44   3e-04
gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I...    44   3e-04
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      44   3e-04
gi|169173182 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04
gi|57222570 codanin 1 [Homo sapiens]                                   44   3e-04
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             44   3e-04
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     44   3e-04
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [...    43   4e-04

>gi|169173078 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 402

 Score =  827 bits (2136), Expect = 0.0
 Identities = 402/402 (100%), Positives = 402/402 (100%)

Query: 1   MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQR 60
           MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQR
Sbjct: 1   MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQR 60

Query: 61  PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS 120
           PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS
Sbjct: 61  PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS 120

Query: 121 CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS 180
           CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS
Sbjct: 121 CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS 180

Query: 181 SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR 240
           SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR
Sbjct: 181 SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR 240

Query: 241 HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP 300
           HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP
Sbjct: 241 HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP 300

Query: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360
           NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS
Sbjct: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360

Query: 361 IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402
           IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR
Sbjct: 361 IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402


>gi|169172508 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 402

 Score =  825 bits (2132), Expect = 0.0
 Identities = 401/402 (99%), Positives = 401/402 (99%)

Query: 1   MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQR 60
           MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGG GAGVRPEPCAGQR
Sbjct: 1   MRGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGGGAGVRPEPCAGQR 60

Query: 61  PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS 120
           PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS
Sbjct: 61  PAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS 120

Query: 121 CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS 180
           CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS
Sbjct: 121 CFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWAS 180

Query: 181 SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR 240
           SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR
Sbjct: 181 SWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSR 240

Query: 241 HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP 300
           HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP
Sbjct: 241 HRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRP 300

Query: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360
           NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS
Sbjct: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360

Query: 361 IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402
           IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR
Sbjct: 361 IARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402


>gi|169173306 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 281

 Score =  383 bits (983), Expect = e-106
 Identities = 189/190 (99%), Positives = 189/190 (99%)

Query: 213 PGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAP 272
           P RRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAP
Sbjct: 92  PRRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAP 151

Query: 273 KPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGA 332
           KPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGA
Sbjct: 152 KPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGA 211

Query: 333 SSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLP 392
           SSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLP
Sbjct: 212 SSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLP 271

Query: 393 SEESLSQRSR 402
           SEESLSQRSR
Sbjct: 272 SEESLSQRSR 281



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 6/111 (5%)

Query: 265 APGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATL 324
           +P LPR   P+ G        R  ++  +L G P P    R  P   H   +       L
Sbjct: 32  SPALPRPGFPAPGFPALRLPRRRAQLGVKLGGGPSPASGARPSP---HLEGAGCETRPWL 88

Query: 325 RAPPGRGASSETMWP--TENLSSRRRAPPQR-RRTRAPSIARSLPGSGRLQ 372
              P R  +     P     L  R  A P R RR RAP +A  + G  R++
Sbjct: 89  GPRPRRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIR 139


>gi|239749426 PREDICTED: hypothetical protein XP_002347042 [Homo
           sapiens]
          Length = 517

 Score =  154 bits (388), Expect = 2e-37
 Identities = 139/348 (39%), Positives = 163/348 (46%), Gaps = 90/348 (25%)

Query: 9   RDLRLAAGAGQAW-------------------GSAGRGRRGPAPRGQTGTQGVGSGGSGA 49
           RDLR+A GAG+                     G  GRG+R    R +  T  V      A
Sbjct: 196 RDLRVAVGAGRRAVPGHRGGEESRVGVHAVQRGRVGRGQRVAVERRRAQTLAVAV--VAA 253

Query: 50  GVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGW--GTVLVSGLVPQDPRAAPPPGGR 107
            VR +    QR AGG+AL GE +AQA  G+AAA G   G + +S  V +       P   
Sbjct: 254 HVRRQ----QRRAGGEALLGELEAQAVHGHAAALGAQRGRLRLSQAVQEAALHPLQP--- 306

Query: 108 QLLLLRPPRWV-------------PSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQ 154
            L LL PPR V             P C  + +   + Q  R P                 
Sbjct: 307 -LHLLAPPRPVLVVGVVLHVLHAQPLCLLH-EGPLLRQRQRLP----------------- 347

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP----TWKAPDARLALGSA 210
                   R      A  GV + W      + RQPLAL L P      + PD  LALGSA
Sbjct: 348 --------RLACTHLAQLGVVQVWI-----LLRQPLALVLSPHHESVHRPPDTGLALGSA 394

Query: 211 RGPGR------RLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHG 264
           RGPGR      RLALHL VP+GA++LGP  GAQP  HR QRA GLALVVTGVSRIR AHG
Sbjct: 395 RGPGRCSAVRRRLALHLHVPDGAQRLGPGAGAQPGHHRGQRALGLALVVTGVSRIRAAHG 454

Query: 265 APGLPRAPKPSAGRGGK--EGGERGTEMLR---RLRGSPRPNRHPRSG 307
           APGLPR+P+PSAGR      G   G+E LR      G P  +R P SG
Sbjct: 455 APGLPRSPQPSAGRAASPDPGEGVGSEALRCPEGCAGLPARSRRPCSG 502


>gi|239743560 PREDICTED: hypothetical protein XP_002342893 [Homo
           sapiens]
          Length = 517

 Score =  154 bits (388), Expect = 2e-37
 Identities = 139/348 (39%), Positives = 163/348 (46%), Gaps = 90/348 (25%)

Query: 9   RDLRLAAGAGQAW-------------------GSAGRGRRGPAPRGQTGTQGVGSGGSGA 49
           RDLR+A GAG+                     G  GRG+R    R +  T  V      A
Sbjct: 196 RDLRVAVGAGRRAVPGHRGGEESRVGVHAVQRGRVGRGQRVAVERRRAQTLAVAV--VAA 253

Query: 50  GVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGW--GTVLVSGLVPQDPRAAPPPGGR 107
            VR +    QR AGG+AL GE +AQA  G+AAA G   G + +S  V +       P   
Sbjct: 254 HVRRQ----QRRAGGEALLGELEAQAVHGHAAALGAQRGRLRLSQAVQEAALHPLQP--- 306

Query: 108 QLLLLRPPRWV-------------PSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQ 154
            L LL PPR V             P C  + +   + Q  R P                 
Sbjct: 307 -LHLLAPPRPVLVVGVVLHVLHAQPLCLLH-EGPLLRQRQRLP----------------- 347

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP----TWKAPDARLALGSA 210
                   R      A  GV + W      + RQPLAL L P      + PD  LALGSA
Sbjct: 348 --------RLACTHLAQLGVVQVWI-----LLRQPLALVLSPHHESVHRPPDTGLALGSA 394

Query: 211 RGPGR------RLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHG 264
           RGPGR      RLALHL VP+GA++LGP  GAQP  HR QRA GLALVVTGVSRIR AHG
Sbjct: 395 RGPGRCSAVRRRLALHLHVPDGAQRLGPGAGAQPGHHRGQRALGLALVVTGVSRIRAAHG 454

Query: 265 APGLPRAPKPSAGRGGK--EGGERGTEMLR---RLRGSPRPNRHPRSG 307
           APGLPR+P+PSAGR      G   G+E LR      G P  +R P SG
Sbjct: 455 APGLPRSPQPSAGRAASPDPGEGVGSEALRCPEGCAGLPARSRRPCSG 502


>gi|239754887 PREDICTED: hypothetical protein XP_002346152 [Homo
           sapiens]
          Length = 517

 Score =  153 bits (387), Expect = 2e-37
 Identities = 139/348 (39%), Positives = 162/348 (46%), Gaps = 90/348 (25%)

Query: 9   RDLRLAAGAGQAW-------------------GSAGRGRRGPAPRGQTGTQGVGSGGSGA 49
           RDLR+A GAG+                     G  GRG+R    R +  T  V      A
Sbjct: 196 RDLRVAVGAGRRAVPGHRGGEESRVGVHAVQRGRVGRGQRVAVERRRAQTLAVAV--VAA 253

Query: 50  GVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGW--GTVLVSGLVPQDPRAAPPPGGR 107
            VR +    QR AGG+AL GE +AQA  G+AAA G   G + +S  V +       P   
Sbjct: 254 HVRRQ----QRRAGGEALLGELEAQAVHGHAAALGAQRGRLRLSQAVQEAALHPLQP--- 306

Query: 108 QLLLLRPPRWV-------------PSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQ 154
            L LL PPR V             P C  + +   + Q  R P                 
Sbjct: 307 -LHLLAPPRPVLVVGVVLHVLHAQPLCLLH-EGPLLRQRQRLP----------------- 347

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP----TWKAPDARLALGSA 210
                   R      A  GV + W      + RQPLAL L P      + PD  LALGSA
Sbjct: 348 --------RLACTHLAQLGVVQVWI-----LLRQPLALVLSPHHESVHRPPDTGLALGSA 394

Query: 211 RGPGR------RLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHG 264
           RGPGR      RLALHL VP+GA++LGP  GAQP  HR QRA GLALVVTGVSRIR AHG
Sbjct: 395 RGPGRCSAVRRRLALHLHVPDGAQRLGPGAGAQPGHHRGQRALGLALVVTGVSRIRAAHG 454

Query: 265 APGLPRAPKPSAGRGGK--EGGERGTEMLR---RLRGSPRPNRHPRSG 307
           APGLPR+P+PSAGR      G   G E LR      G P  +R P SG
Sbjct: 455 APGLPRSPQPSAGRAASPDPGEGVGNEALRCPEGCAGLPARSRRPCSG 502


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 101/379 (26%), Positives = 140/379 (36%), Gaps = 76/379 (20%)

Query: 22  GSAGRGRRGPA-PRGQTGTQGVGSGGSGAGVRPE--------PCAGQRP---AGGKALRG 69
           GS+  GR GP+ PRG   ++   S G  +   PE        P +   P   AGG A  G
Sbjct: 142 GSSSYGRLGPSEPRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSA--G 199

Query: 70  EGQAQAAQGYAAANGWGTVL-VSGLVPQDPRAAPPP---------GGRQL-----LLLRP 114
                +A+  A A  + T   +  +  + PR    P          GR L      LLR 
Sbjct: 200 PEACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRR 259

Query: 115 PRWVPSCFPNSQ--SADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASP 172
            R   +  P +    AD     +   ++RP     P    A+P+      R G   ++  
Sbjct: 260 RRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDA-SPSPGSARPAREPSLERVGGHPTSPA 318

Query: 173 GVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGP 232
            + R+WASSW          +  P   AP A  +   +   GR   +  Q   GA+    
Sbjct: 319 ALSRAWASSWES--------EAAPEPAAPPAAPSPPDSPAEGR--LVKAQYIPGAQ---A 365

Query: 233 RTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLR 292
            T   P R  R++ P L       +R R    +P  PR    +AGR G+     G     
Sbjct: 366 ATRGLPGRAARRKPPPL-------TRGRSVEQSP--PRERPRAAGRRGRMAEASGR---- 412

Query: 293 RLRGSPRPNRHPRS-GPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPP 351
             RGSPR  +  RS       G ASA         PP         +PT      R  PP
Sbjct: 413 --RGSPRARKASRSQSETSLLGRASAVPS-----GPP--------KYPTAEREEPR--PP 455

Query: 352 QRRRTRAPSIARSLPGSGR 370
           + RR  AP++A    GS R
Sbjct: 456 RPRRGPAPTLAAQAAGSCR 474



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 99/384 (25%), Positives = 126/384 (32%), Gaps = 74/384 (19%)

Query: 1   MRGLRACSR---DLRLAAGAGQ---AWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPE 54
           MR  R C R   D   A GAG+    + SA   RR     GQ  T     GG+  G R +
Sbjct: 226 MRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTS---PGGADGGPRRQ 282

Query: 55  PCAGQRPAGGKALRG------EGQAQAAQGY-----AAANGWGTVLVSGLVPQD--PRAA 101
               QRP       G      E   +   G+     A +  W +   S   P+   P AA
Sbjct: 283 NSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAA 342

Query: 102 P-PPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRG 160
           P PP       L   +++P     +Q+A      R  A+R+P         +  P   R 
Sbjct: 343 PSPPDSPAEGRLVKAQYIPG----AQAATRGLPGRA-ARRKPPPLTRGRSVEQSPPRER- 396

Query: 161 SRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALH 220
                 PR+A      + AS   G PR       R   ++      LG A          
Sbjct: 397 ------PRAAGRRGRMAEASGRRGSPRA------RKASRSQSETSLLGRASA-------- 436

Query: 221 LQVPEGARQL--GPRTGAQPSRHRRQRAPGLALVVTGVSR-------IRPAHGAPGLPRA 271
             VP G  +     R   +P R RR  AP LA    G  R       I  A G    PRA
Sbjct: 437 --VPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRA 494

Query: 272 PKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPV----PAHGV----------ASA 317
           P       G         +L    GS       R GP+    PA GV          AS 
Sbjct: 495 PAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSASE 554

Query: 318 AAGPATLRAPPGRGASSETMWPTE 341
              PA   A      S   +WP +
Sbjct: 555 GESPAFSSASSDSDGSGGLVWPQQ 578


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 77/312 (24%), Positives = 106/312 (33%), Gaps = 41/312 (13%)

Query: 95  PQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQ 154
           P+ P+ AP PG  + +              S S          AKR  +H + P      
Sbjct: 438 PESPKPAPAPGSHREI--------------SSSPTSKNRSHGRAKRDKSHSHTPS----- 478

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPG 214
               R   R  SP +A  G  RS   +  G  R        P W+   +    G +R P 
Sbjct: 479 ----RRMGRSRSPATAKRGRSRSRTPTKRGHSRSR-----SPQWRRSRSAQRWGRSRSPQ 529

Query: 215 RR-LALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIR-PAHGAPGLPRAP 272
           RR  +   Q P  +R    +   +    RR R+   +    G SR R PA       R P
Sbjct: 530 RRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTP 589

Query: 273 --KPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGR 330
             + S  R       R     RR R   R     RS         S     +  R+P  R
Sbjct: 590 ARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR------TRSPVRRRSRSRSPARR 643

Query: 331 GASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPP 390
              S +  P     SR R P +R R+R+ + AR    SGR +       G++  R     
Sbjct: 644 SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARR---SGRSRSRTPARRGRSRSRTPRRG 700

Query: 391 LPSEESLSQRSR 402
                SL +R R
Sbjct: 701 RSRSRSLVRRGR 712



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 101/424 (23%), Positives = 149/424 (35%), Gaps = 61/424 (14%)

Query: 23   SAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAG------QRPAGGKALRGEGQAQAA 76
            S  R R G +P  +   +      SG+   PEP A       +R   G + +G G +   
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEG 1651

Query: 77   QGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPS-CFPN-SQSADISQED 134
                 ++       S    +  R++P P  +      PPR   S   P  ++ A +S+  
Sbjct: 1652 SSSTESSPEHPPK-SRTARRGSRSSPEPKTKSRT---PPRRRSSRSSPELTRKARLSRRS 1707

Query: 135  RKPAKRRPTHFYHPDEHKAQPS--------HVRGSRR---PGSPRSASPGV-GRSWASSW 182
            R  +    T    P  H+  PS          R SRR     SPR+ +    GRS +   
Sbjct: 1708 RSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKP 1767

Query: 183  AGVPRQPLALDLRPTWKAPDARLALGSARGPGRRL-----------------ALHLQVPE 225
             G+ R   +   R   +    R   GS++   RR                    H + P 
Sbjct: 1768 RGLQRSR-SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP- 1825

Query: 226  GARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGE 285
             ARQ   RT ++  R R +  P         SR  PA       RA  P+  R  +    
Sbjct: 1826 -ARQESSRTSSRRRRGRSRTPPTSRK--RSRSRTSPAPWKRSRSRA-SPATHRRSRSRTP 1881

Query: 286  RGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLR-----APPGRGASSETMWPT 340
              +    R R SP   R  RS        + + A P + R      PP     S +  PT
Sbjct: 1882 LISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPT 1941

Query: 341  ENLSSRRRAPP---QRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESL 397
                SR R PP   +R R+R P + R      R +    P T +   R ++ P+    S 
Sbjct: 1942 TRRRSRSRTPPVTRRRSRSRTPPVTRR-----RSRSRTSPITRRR-SRSRTSPVTRRRSR 1995

Query: 398  SQRS 401
            S+ S
Sbjct: 1996 SRTS 1999



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 69/303 (22%), Positives = 103/303 (33%), Gaps = 37/303 (12%)

Query: 13   LAAGAGQAWGSAGRGRRG----PAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALR 68
            L++GA     S+     G    PAP       G     +GA  +P   A  +PA  +   
Sbjct: 2475 LSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQ-QPSALAALQPAKERRSS 2533

Query: 69   GEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSA 128
                + ++   ++++   +   SG    D   +  P   ++ L R P   P+  P     
Sbjct: 2534 SSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPA--PKEAVR 2591

Query: 129  DISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQ 188
            +    +  PAKR+           +  S    S    S  S+S     S +SS +  P  
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS- 2650

Query: 189  PLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPG 248
                   P    P A     S + P          P   R   PR      R  R     
Sbjct: 2651 -------PAKPGPQALPKPASPKKPP---------PGERRSRSPRKPIDSLRDSR----- 2689

Query: 249  LALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERG-----TEMLRRLRGSPRPNRH 303
             +L  + V R RP+      PR  + S+   G   G+RG     +   RR   SPRP RH
Sbjct: 2690 -SLSYSPVERRRPSPQPS--PRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRH 2746

Query: 304  PRS 306
              S
Sbjct: 2747 RSS 2749



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 35/125 (28%), Positives = 50/125 (40%), Gaps = 11/125 (8%)

Query: 124  NSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWA 183
            +S S+  S     PAK  P     P   K  P   R SR   SPR     +  S + S++
Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR---SPRKPIDSLRDSRSLSYS 2694

Query: 184  GVPRQPLALDLRPT-WKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHR 242
             V R+      RP+   +P  + +  S RG  R      + P   R+       +P RHR
Sbjct: 2695 PVERR------RPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRR-RETPSPRPMRHR 2747

Query: 243  RQRAP 247
              R+P
Sbjct: 2748 SSRSP 2752


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 74/313 (23%), Positives = 103/313 (32%), Gaps = 75/313 (23%)

Query: 98  PRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRR---------PTHFYHP 148
           P  A PP   +  L  PP+       ++Q+A+I Q  ++   R+         P+     
Sbjct: 674 PEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGG 733

Query: 149 DEHKAQPSHVRGSRRPGSPR-SASPGV-GRSWASSWAGV-------PRQPLALDLRPTWK 199
           D+    P  V    RP  P    SP   G    S W G        PR+PL+        
Sbjct: 734 DDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPLS-------- 785

Query: 200 APDARLALGSARGPGRRLALHLQVPEGARQLGPRT--GAQPSRHRRQRAPGLALVVTGVS 257
                                   P+G+R   P    G+ P   R   +PG  +  T   
Sbjct: 786 ------------------------PQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSF 821

Query: 258 RIRPAHGAPGLPRAPKPSAG-------RGGKEGG--------------ERGTEMLRRLRG 296
              P +  P + +AP P AG       R GK+                ER    LR  + 
Sbjct: 822 ASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQS 881

Query: 297 SPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRT 356
              P   P    +P     + AA  AT+R  P      +  + T N +   R PP R   
Sbjct: 882 PEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRATA 941

Query: 357 RAPSIARSLPGSG 369
           R P   R  PG G
Sbjct: 942 RLPQ--RGCPGDG 952


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sapiens]
          Length = 1086

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 74/313 (23%), Positives = 103/313 (32%), Gaps = 75/313 (23%)

Query: 98   PRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRR---------PTHFYHP 148
            P  A PP   +  L  PP+       ++Q+A+I Q  ++   R+         P+     
Sbjct: 752  PEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPGG 811

Query: 149  DEHKAQPSHVRGSRRPGSPR-SASPGV-GRSWASSWAGV-------PRQPLALDLRPTWK 199
            D+    P  V    RP  P    SP   G    S W G        PR+PL+        
Sbjct: 812  DDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEETSQWPGPASPPRVPPREPLS-------- 863

Query: 200  APDARLALGSARGPGRRLALHLQVPEGARQLGPRT--GAQPSRHRRQRAPGLALVVTGVS 257
                                    P+G+R   P    G+ P   R   +PG  +  T   
Sbjct: 864  ------------------------PQGSRTPSPLVPPGSSPLPPRLSSSPGKTMPTTQSF 899

Query: 258  RIRPAHGAPGLPRAPKPSAG-------RGGKEGG--------------ERGTEMLRRLRG 296
               P +  P + +AP P AG       R GK+                ER    LR  + 
Sbjct: 900  ASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQS 959

Query: 297  SPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRT 356
               P   P    +P     + AA  AT+R  P      +  + T N +   R PP R   
Sbjct: 960  PEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARPPPPRATA 1019

Query: 357  RAPSIARSLPGSG 369
            R P   R  PG G
Sbjct: 1020 RLPQ--RGCPGDG 1030


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 88/364 (24%), Positives = 116/364 (31%), Gaps = 55/364 (15%)

Query: 25  GRGRRGPAPRGQTGTQGVGS---GGSGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAA 81
           G+  R P P+GQ G  G      G  G      P   Q P G +  +GE  A   +G   
Sbjct: 25  GQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDG 84

Query: 82  ANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRR 141
             G          P +P    PPG         P   P    N  +      D K     
Sbjct: 85  EPG---------TPGNPGPPGPPG---------PPGPPGLGGNFAAQMAGGFDEKAGG-- 124

Query: 142 PTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLR------ 195
                      AQ   ++G   P  PR      G      + G P +P    +       
Sbjct: 125 -----------AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPR 173

Query: 196 ----PTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGL-- 249
               P  K  D     G A  PG+        P+GAR   P T   P     +  PGL  
Sbjct: 174 GPPGPPGKPGDD----GEAGKPGKAGERGPPGPQGARGF-PGTPGLPGVKGHRGYPGLDG 228

Query: 250 ALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPV 309
           A    G   ++   G+PG   +P P   RG    GERG        G+   +  P  GP 
Sbjct: 229 AKGEAGAPGVKGESGSPGENGSPGPMGPRGLP--GERGRTGPAGAAGARGNDGQP--GPA 284

Query: 310 PAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSG 369
              G    A GP    AP  +G +  T       +   R  P    +  P+ A   PG+ 
Sbjct: 285 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344

Query: 370 RLQG 373
            + G
Sbjct: 345 GIPG 348



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 98/406 (24%), Positives = 128/406 (31%), Gaps = 78/406 (19%)

Query: 16  GAGQAWGSAG-RGRRGP----APRGQTGTQGV-GSGGSGAGVRPEPCAGQRPAGGK---- 65
           GA  A G AG  G RGP     PRG+ GT G  G  G+      +   G + + G     
Sbjct: 300 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 359

Query: 66  ------ALRGEGQAQAAQGYAAANGW-GTVLVSGLV-PQDPRAAPPPGGRQLLLLRPPRW 117
                   RG    Q A G     G  G   ++G    Q P+  P P G           
Sbjct: 360 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG----------- 408

Query: 118 VPSCFPNSQSADISQEDRKPAKRRP----------------THFYHPDEHKAQPSHVRGS 161
                P        +E ++ A+  P                   +   +  A P    G 
Sbjct: 409 -----PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 463

Query: 162 RRPGS---PRSASPGVGRSWASSWAGVPRQPLALDL--RPTWKAPDARLALGSARGPGRR 216
           R P     P+ A+   GR       G P  P A  L  RP    P  ++  G +  PG  
Sbjct: 464 RGPSGLAGPKGANGDPGRP------GEPGLPGARGLTGRPGDAGPQGKV--GPSGAPGED 515

Query: 217 LALHLQVPEGARQL-------GPR-TGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGL 268
                  P+GAR         GP+    +P +   +  PG      G+  +    G  G 
Sbjct: 516 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPG----APGLRGLPGKDGETGA 571

Query: 269 PRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPA-HGVASAAAGPATLRAP 327
              P P+   G  E GE+G       +G P P   P  G  P   GV   A  P  +   
Sbjct: 572 AGPPGPAGPAG--ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPR 629

Query: 328 PGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQG 373
             RG   E   P        R  P    T  P  A    G    QG
Sbjct: 630 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG 675



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 89/325 (27%), Positives = 108/325 (33%), Gaps = 71/325 (21%)

Query: 17   AGQAWGSAGRGRRGP----APRGQTGTQGV--GSGGSGAGVRPEPCAGQRPAGGKALRGE 70
            AG+       G  GP     P G+ G +G    SG  G    P       P G K   G+
Sbjct: 833  AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 892

Query: 71   GQAQAAQGYAAANGW-GTVLVSGLVPQDPRAAPP--PGGRQLLLLRPPRWVPSCFPNSQS 127
                 A+G     G  G   + GL  Q      P  PG             PS  P  Q 
Sbjct: 893  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-------------PSGEPGKQG 939

Query: 128  ADISQEDR-KPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVP 186
            A  +  DR  P    P     P     +P       R GSP +  P  GR  A+   G  
Sbjct: 940  APGASGDRGPPGPVGPPGLTGP---AGEPG------REGSPGADGPP-GRDGAAGVKG-- 987

Query: 187  RQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRA 246
                  D   T        A+G+   PG         P G+      TG Q  R      
Sbjct: 988  ------DRGETG-------AVGAPGAPG---------PPGSPGPAGPTGKQGDRGEAGAQ 1025

Query: 247  PGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEG--GERGTEMLRRLRGSPRPNRHP 304
              +    +G +  R   G  G PR  K  AG  G+ G  G RG   L+ L G P      
Sbjct: 1026 GPMG--PSGPAGARGIQGPQG-PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP------ 1076

Query: 305  RSGPVPAHGVASAAAGPATLRAPPG 329
              GP    G AS  AGP+  R PPG
Sbjct: 1077 --GPSGDQG-ASGPAGPSGPRGPPG 1098



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 34/105 (32%), Positives = 41/105 (39%), Gaps = 10/105 (9%)

Query: 13   LAAGAGQAWGSAGRGRRGPAPR-GQTGTQGVG--SGGSGAGVRPEPCAGQRPAGGKALRG 69
            L   AG+       G  GP  R G  G +G    +G  GA   P P     PAG    +G
Sbjct: 958  LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017

Query: 70   EGQAQAAQGYAAANG-WGTVLVSGLVPQDPRA----APPPGGRQL 109
            +     AQG    +G  G   + G  PQ PR     A  PG R L
Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQG--PQGPRGDKGEAGEPGERGL 1060


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 99/394 (25%), Positives = 125/394 (31%), Gaps = 85/394 (21%)

Query: 26  RGRRGP-APRGQTGTQGVGSGGS-GAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAAN 83
           RGR GP  PRG+ G  G G  G  GA   P P       G    +G   +   QG     
Sbjct: 623 RGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPV 682

Query: 84  GW----GTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAK 139
           G     G V + G V  D     PPG +     + PR +                 +P  
Sbjct: 683 GLQGLRGEVGLPG-VKGDKGPMGPPGPKGDQGEKGPRGLTG---------------EPGM 726

Query: 140 RR-PTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTW 198
           R  P     P          +G+  P  P       G    +   G+   P         
Sbjct: 727 RGLPGAVGEPG--------AKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPP--------- 769

Query: 199 KAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSR 258
                    G +  PG+      Q P+G     P T  +P       APG  +   G S 
Sbjct: 770 ---------GPSGDPGKPGLTGPQGPQGL----PGTPGRPGIKGEPGAPGKIVTSEGSSM 816

Query: 259 IRP--------AHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVP 310
           +          A G PG P AP P AG  G  G +     +  L+G P P   PR  P P
Sbjct: 817 LTVPGPPGPPGAMGPPGPPGAPGP-AGPAGLPGHQE----VLNLQGPPGPPG-PRGPPGP 870

Query: 311 AHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRR---------APPQRRRTRAPSI 361
           +        GP   R PPG G       P   LS+             PP  +  + P  
Sbjct: 871 S------IPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPG 924

Query: 362 ARSLPGSGRLQGLI---FPSTGKNVQRHKSPPLP 392
            R   G   L G       S G N+Q    PP P
Sbjct: 925 PRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGP 958



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 85/323 (26%), Positives = 102/323 (31%), Gaps = 54/323 (16%)

Query: 22  GSAG-RGRRGPAP----RGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQAA 76
           GS G +G  GP      RG+ G  GV  G  G    P P   Q   G + L GE   +  
Sbjct: 671 GSPGPQGPPGPVGLQGLRGEVGLPGV-KGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGL 729

Query: 77  QGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRK 136
            G     G        + P  P     P G Q L   P    P       S D       
Sbjct: 730 PGAVGEPG----AKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPP----GPSGD------- 774

Query: 137 PAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP 196
           P K   T    P      P        PG+P       G    SS   VP  P       
Sbjct: 775 PGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEG----SSMLTVPGPPGPPGAMG 830

Query: 197 TWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGV 256
               P A    G A  PG +  L+LQ P G    GPR    PS       PG        
Sbjct: 831 PPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP--GPRGPPGPSI---PGPPG-------- 877

Query: 257 SRIRPAHGAPGLPRAPKPS--------AGRGGKEG--GERGTEMLRRLRGSPRPNRHPRS 306
            R  P  G PG P  P           +G  G  G  G +G +      G P P  H   
Sbjct: 878 PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQ------GPPGPRGHQGE 931

Query: 307 GPVPAHGVASAAAGPATLRAPPG 329
             +P    + +++    L+ PPG
Sbjct: 932 QGLPGFSTSGSSSFGLNLQGPPG 954



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 31/90 (34%), Positives = 37/90 (41%), Gaps = 11/90 (12%)

Query: 26   RGRRGP-APRGQTGTQGVG----SGGSGAGVR----PEPCAGQRPAGGKALRG-EGQAQA 75
            +G +GP  PRG  G QG+     SG S  G+     P P   Q P G K   G  G    
Sbjct: 917  KGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGI 976

Query: 76   AQGYAAANGWGTVLVSGLVPQDPRAAPPPG 105
              G +      T+ VSG  P  P    PPG
Sbjct: 977  PSGPSEGGSSSTMYVSG-PPGPPGPPGPPG 1005



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 23/60 (38%), Positives = 26/60 (43%), Gaps = 3/60 (5%)

Query: 28   RRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQR-PAGGKALRGEGQAQAAQG--YAAANG 84
            RRG +      T G G+G  GAG      AG R P G     G G   AA+G  YA   G
Sbjct: 1302 RRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGG 1361


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 86/337 (25%), Positives = 107/337 (31%), Gaps = 85/337 (25%)

Query: 26  RGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGW 85
           RG RGPA  G  G  G+     G    P P     P G   L G    Q + GY   +  
Sbjct: 120 RGPRGPA--GPPGRDGI----PGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTG 173

Query: 86  GTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPTHF 145
           G  +   + P  PR  P P                                P    P  F
Sbjct: 174 GISVPGPMGPSGPRGLPGP--------------------------------PGAPGPQGF 201

Query: 146 YHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARL 205
             P     +P    G+  P  PR      G++     AG P +P     R       AR 
Sbjct: 202 QGPPGEPGEP----GASGPMGPRGPPGPPGKNGDDGEAGKPGRP---GERGPPGPQGARG 254

Query: 206 ALGSARGPGRRLALHLQVPEGAR----------------------QLGPRTGAQPSRHRR 243
             G+A  PG +        +GA+                      Q+GPR    P    R
Sbjct: 255 LPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPR--GLPGERGR 312

Query: 244 QRAPGLALVVTGVSRIRPAHGAPGL--PRAPKPSAGRGGKEG-----GERGTEMLRRLRG 296
             APG A    G      A G PG   P  P    G  G +G     G RG+E  + +RG
Sbjct: 313 PGAPGPA-GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRG 371

Query: 297 SPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGAS 333
            P P       P PA G A  A  P     P  +GA+
Sbjct: 372 EPGP-------PGPA-GAAGPAGNPGADGQPGAKGAN 400



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 116/409 (28%), Positives = 138/409 (33%), Gaps = 81/409 (19%)

Query: 15  AGAGQAWGSAGR-GRRG-PAPRGQTGTQGVGSGGSGAGVRPEPCAGQR----PAGGKALR 68
           AG   + G AGR G  G P  +G TG+ G  S G      P   AGQ     P G    R
Sbjct: 517 AGPKGSPGEAGRPGEAGLPGAKGLTGSPG--SPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574

Query: 69  GEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPG-----GRQLLLLRPP-------- 115
           G+       G   A G         VP  P A  P G     G Q     PP        
Sbjct: 575 GQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ----GPPGPAGPAGE 630

Query: 116 --RWVPSCFPNSQS----ADISQEDRKPAKRR-PTHFYHPDEHKAQPSH-------VRGS 161
                P+  P  Q     A    E  KP ++  P     P    A+          V+G 
Sbjct: 631 RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGP 690

Query: 162 RRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHL 221
             P  PR A+   G   A   AG P             AP ++ A G    PG R A  L
Sbjct: 691 PGPAGPRGANGAPGNDGAKGDAGAP------------GAPGSQGAPGLQGMPGERGAAGL 738

Query: 222 QVPEGAR-QLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAP--KPSAGR 278
             P+G R   GP+ GA  S       PG      GV  +    G PG   AP  K  +G 
Sbjct: 739 PGPKGDRGDAGPK-GADGS-------PG----KDGVRGLTGPIGPPGPAGAPGDKGESGP 786

Query: 279 GGKEG--GERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRA-----PPGRG 331
            G  G  G RG    R   G P P     +GP  A G   A   P    A     PPG  
Sbjct: 787 SGPAGPTGARGAPGDRGEPGPPGPAGF--AGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844

Query: 332 ASSETMWPTENLSSRRRAPPQR--RRTRAPSIARSLPGSGRLQGLIFPS 378
             +    P  N+     AP  +  R +  P  A   PG+    G   PS
Sbjct: 845 GPAGPPGPIGNVG----APGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 91/339 (26%), Positives = 113/339 (33%), Gaps = 71/339 (20%)

Query: 16  GAGQAWGSAGR-GRRGPAPRGQTGTQGVGSGGSGAGVRPEPCA-GQRPAGG----KALRG 69
           GA    G+AG  G +G   RG +G  G       AG + EP + G+  A G    + L G
Sbjct: 251 GARGLPGTAGLPGMKGH--RGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG 308

Query: 70  EGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSAD 129
           E     A G A A G      +   P     A PPG                FP +  A 
Sbjct: 309 ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG----------------FPGAVGA- 351

Query: 130 ISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQP 189
                               + +A P   RGS  P   R      G + A+  AG P   
Sbjct: 352 --------------------KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP--- 388

Query: 190 LALDLRPTWKAPDARLALGSARG-PGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPG 248
              D +P  K  +    +  A G PG R       P G +  GP  G  P        PG
Sbjct: 389 -GADGQPGAKGANGAPGIAGAPGFPGAR------GPSGPQ--GP--GGPPGPKGNSGEPG 437

Query: 249 LALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEG--GERGTEMLRRLRGSPRPNRHPRS 306
                 G      A G PG P   +   G  G+EG  G RG      L G P     P S
Sbjct: 438 ----APGSKGDTGAKGEPG-PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS 492

Query: 307 GPVPAHGVASAAAGPATLRAPPG----RGASSETMWPTE 341
              P     +   GPA  R  PG    +G+  E   P E
Sbjct: 493 RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE 531



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 87/320 (27%), Positives = 103/320 (32%), Gaps = 82/320 (25%)

Query: 17   AGQAWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQAA 76
            AG+  G   RG  GPA  G+ G  G       AG +  P A   PAG     G       
Sbjct: 901  AGKEGGKGPRGETGPA--GRPGEVGPPGPPGPAGEKGSPGA-DGPAGAPGTPG------P 951

Query: 77   QGYAAANGWGTVLVSGLVPQDPRAAPP--PGGRQLLLLRPPRWVPSCFPNSQS-ADISQE 133
            QG A   G     V GL  Q      P  PG             PS  P  Q  +  S E
Sbjct: 952  QGIAGQRG-----VVGLPGQRGERGFPGLPG-------------PSGEPGKQGPSGASGE 993

Query: 134  DRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGV-GRSWASSWAGVPRQPLAL 192
               P    P     P     +         PG  R  SPG  G    +  AG P  P   
Sbjct: 994  RGPPGPMGPPGLAGPPGESGREGAPGAEGSPG--RDGSPGAKGDRGETGPAGPPGAP--- 1048

Query: 193  DLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALV 252
                   AP A   +G A   G R       P G   +GP  GA+               
Sbjct: 1049 ------GAPGAPGPVGPAGKSGDRGETGPAGPAG--PVGP-VGAR--------------- 1084

Query: 253  VTGVSRIRPAHGAPGLPRAPKPSAGRGGKEG--GERGTEMLRRLRGSPRPNRHP-RSGPV 309
                         P  P+ P+   G  G++G  G +G      L+G P P   P   GP 
Sbjct: 1085 ------------GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGP- 1131

Query: 310  PAHGVASAAAGPATLRAPPG 329
                  S A+GPA  R PPG
Sbjct: 1132 ------SGASGPAGPRGPPG 1145



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 37/137 (27%), Positives = 44/137 (32%), Gaps = 34/137 (24%)

Query: 264 GAPGLPRAPKPSA-----GRGGKEG------------------GERGTEMLRRLRGSP-R 299
           G PGLP  P P       G GG                     G  G    R L G P  
Sbjct: 136 GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGA 195

Query: 300 PNRHPRSGPV--PAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTR 357
           P      GP   P    AS   GP     PPG+          ++  + +   P  R   
Sbjct: 196 PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNG--------DDGEAGKPGRPGERGPP 247

Query: 358 APSIARSLPGSGRLQGL 374
            P  AR LPG+  L G+
Sbjct: 248 GPQGARGLPGTAGLPGM 264


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 89/367 (24%), Positives = 113/367 (30%), Gaps = 79/367 (21%)

Query: 17  AGQAWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQAA 76
           +G   G+AG G   PA            G  GA   P P    RP GG            
Sbjct: 64  SGSPAGAAGAGPAAPA-----------EGAPGAAPEPPPAGRARPGGG----------GP 102

Query: 77  QGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRK 136
           Q     +    ++ +G  P   +  PPP G             SC P   +A ++    +
Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS----------AGSCAPVPAAAAVA-AGPE 151

Query: 137 PAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP 196
           PA   P          A P+ +     PG      PG G          P +P       
Sbjct: 152 PAPAGPA-------KPAGPAALAARAGPGPGPGPGPGPGPG--------PGKPAGPGAAQ 196

Query: 197 TWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGV 256
           T     A L    A  P   L     V  G   L P          +  APG  +     
Sbjct: 197 TLNGSAALLNSHHAAAPAVSL-----VNNGPAALLPLP--------KPAAPGTVIQTPPF 243

Query: 257 --SRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPR--PNRHPRSGPV--- 309
             +   PA  AP  P AP P+A              L R  G P   P   P   P    
Sbjct: 244 VGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAA 303

Query: 310 -------PAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIA 362
                   A   A AA GPA +   PG GA++    P     S     P+R    AP  A
Sbjct: 304 QNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAES-----PKRVVQAAPPAA 358

Query: 363 RSLPGSG 369
           ++L  SG
Sbjct: 359 QTLAASG 365


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 106/412 (25%), Positives = 137/412 (33%), Gaps = 87/412 (21%)

Query: 16  GAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQA 75
           GAG   G  G G  G    G  G  G G GGS  G  P    G   AG   LR       
Sbjct: 64  GAGAGGGGGGFGGGG----GFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDN 119

Query: 76  AQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRW-VPSCFPNSQSADIS-QE 133
             G +       +L  G      +   PP G       P R+ VPS  P  +S     Q 
Sbjct: 120 DSGGSRP----PLLPPGGRSTSAKPFSPPSG-------PGRFPVPS--PGHRSGPPEPQR 166

Query: 134 DRKPAKR-----RPTHFYHPDEHKAQP----SHVRGSRR-PGSPRSASPGV-------GR 176
           +R P  R     +P     P     +P     H RGS   PG PR  SPG         R
Sbjct: 167 NRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNR 226

Query: 177 SWASSWAGVPRQPLA----LDLRPTWKAPDARLALGSARGP-----GRRLALHLQV--PE 225
             A     + + PL+       RP      +R AL     P     G R ++H +   P 
Sbjct: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR-ALDDKPPPPPPPVGNRPSIHREAVPPP 285

Query: 226 GARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGE 285
             +   P   + P      +AP             P    PG P  P P +  G  E   
Sbjct: 286 PPQNNKPPVPSTPRPSASSQAPPPP----------PPPSRPGPP--PLPPSSSGNDETPR 333

Query: 286 RGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSS 345
                L     +P      RSGP+P      +   P  +R PPGR               
Sbjct: 334 LPQRNLSLSSSTPPLPSPGRSGPLPP---PPSERPPPPVRDPPGRSGP------------ 378

Query: 346 RRRAPPQRRRTRAPSIARSLPGSGRL---QGLIFPSTGKNVQRHKSPPLPSE 394
               PP    +R  S +R+LP + +L    G+  P +G        PPLP +
Sbjct: 379 ---LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR------PPLPPD 421


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 106/412 (25%), Positives = 137/412 (33%), Gaps = 87/412 (21%)

Query: 16  GAGQAWGSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQA 75
           GAG   G  G G  G    G  G  G G GGS  G  P    G   AG   LR       
Sbjct: 64  GAGAGGGGGGFGGGG----GFGGGGGGGGGGSFGGGGPPGLGGLFQAGMPKLRSTANRDN 119

Query: 76  AQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRW-VPSCFPNSQSADIS-QE 133
             G +       +L  G      +   PP G       P R+ VPS  P  +S     Q 
Sbjct: 120 DSGGSRP----PLLPPGGRSTSAKPFSPPSG-------PGRFPVPS--PGHRSGPPEPQR 166

Query: 134 DRKPAKR-----RPTHFYHPDEHKAQP----SHVRGSRR-PGSPRSASPGV-------GR 176
           +R P  R     +P     P     +P     H RGS   PG PR  SPG         R
Sbjct: 167 NRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNR 226

Query: 177 SWASSWAGVPRQPLA----LDLRPTWKAPDARLALGSARGP-----GRRLALHLQV--PE 225
             A     + + PL+       RP      +R AL     P     G R ++H +   P 
Sbjct: 227 GTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR-ALDDKPPPPPPPVGNRPSIHREAVPPP 285

Query: 226 GARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGE 285
             +   P   + P      +AP             P    PG P  P P +  G  E   
Sbjct: 286 PPQNNKPPVPSTPRPSASSQAPPPP----------PPPSRPGPP--PLPPSSSGNDETPR 333

Query: 286 RGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSS 345
                L     +P      RSGP+P      +   P  +R PPGR               
Sbjct: 334 LPQRNLSLSSSTPPLPSPGRSGPLPP---PPSERPPPPVRDPPGRSGP------------ 378

Query: 346 RRRAPPQRRRTRAPSIARSLPGSGRL---QGLIFPSTGKNVQRHKSPPLPSE 394
               PP    +R  S +R+LP + +L    G+  P +G        PPLP +
Sbjct: 379 ---LPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPR------PPLPPD 421


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 91/382 (23%), Positives = 119/382 (31%), Gaps = 68/382 (17%)

Query: 7   CSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGTQGVGS---GGSGAGVRPEPCAGQRPAG 63
           C  DL  A+G              P P+GQ G  G      G  G      P   Q P G
Sbjct: 89  CPTDLATASGQ-------------PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRG 135

Query: 64  GKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFP 123
            +  +GE  A   +G     G          P +P    PPG         P   P    
Sbjct: 136 DRGDKGEKGAPGPRGRDGEPG---------TPGNPGPPGPPG---------PPGPPGLGG 177

Query: 124 NSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWA 183
           N  +      D K                AQ   ++G   P  PR      G      + 
Sbjct: 178 NFAAQMAGGFDEKAGG-------------AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQ 224

Query: 184 GVPRQPLALDLR----------PTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPR 233
           G P +P    +           P  K  D     G A  PG+        P+GAR   P 
Sbjct: 225 GNPGEPGEPGVSGPMGPRGPPGPPGKPGDD----GEAGKPGKAGERGPPGPQGARGF-PG 279

Query: 234 TGAQPSRHRRQRAPGL--ALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEML 291
           T   P     +  PGL  A    G   ++   G+PG   +P P   RG    GERG    
Sbjct: 280 TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP--GERGRTGP 337

Query: 292 RRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPP 351
               G+   +  P  GP    G    A GP    AP  +G +  T       +   R  P
Sbjct: 338 AGAAGARGNDGQP--GPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEP 395

Query: 352 QRRRTRAPSIARSLPGSGRLQG 373
               +  P+ A   PG+  + G
Sbjct: 396 GTPGSPGPAGASGNPGTDGIPG 417



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 98/406 (24%), Positives = 128/406 (31%), Gaps = 78/406 (19%)

Query: 16  GAGQAWGSAG-RGRRGP----APRGQTGTQGV-GSGGSGAGVRPEPCAGQRPAGGK---- 65
           GA  A G AG  G RGP     PRG+ GT G  G  G+      +   G + + G     
Sbjct: 369 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 428

Query: 66  ------ALRGEGQAQAAQGYAAANGW-GTVLVSGLV-PQDPRAAPPPGGRQLLLLRPPRW 117
                   RG    Q A G     G  G   ++G    Q P+  P P G           
Sbjct: 429 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG----------- 477

Query: 118 VPSCFPNSQSADISQEDRKPAKRRP----------------THFYHPDEHKAQPSHVRGS 161
                P        +E ++ A+  P                   +   +  A P    G 
Sbjct: 478 -----PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 532

Query: 162 RRPGS---PRSASPGVGRSWASSWAGVPRQPLALDL--RPTWKAPDARLALGSARGPGRR 216
           R P     P+ A+   GR       G P  P A  L  RP    P  ++  G +  PG  
Sbjct: 533 RGPSGLAGPKGANGDPGRP------GEPGLPGARGLTGRPGDAGPQGKV--GPSGAPGED 584

Query: 217 LALHLQVPEGARQL-------GPR-TGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGL 268
                  P+GAR         GP+    +P +   +  PG      G+  +    G  G 
Sbjct: 585 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPG----APGLRGLPGKDGETGA 640

Query: 269 PRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPA-HGVASAAAGPATLRAP 327
              P P+   G  E GE+G       +G P P   P  G  P   GV   A  P  +   
Sbjct: 641 AGPPGPAGPAG--ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPR 698

Query: 328 PGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQG 373
             RG   E   P        R  P    T  P  A    G    QG
Sbjct: 699 GERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG 744



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 89/325 (27%), Positives = 108/325 (33%), Gaps = 71/325 (21%)

Query: 17   AGQAWGSAGRGRRGP----APRGQTGTQGV--GSGGSGAGVRPEPCAGQRPAGGKALRGE 70
            AG+       G  GP     P G+ G +G    SG  G    P       P G K   G+
Sbjct: 902  AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 961

Query: 71   GQAQAAQGYAAANGW-GTVLVSGLVPQDPRAAPP--PGGRQLLLLRPPRWVPSCFPNSQS 127
                 A+G     G  G   + GL  Q      P  PG             PS  P  Q 
Sbjct: 962  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-------------PSGEPGKQG 1008

Query: 128  ADISQEDR-KPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVP 186
            A  +  DR  P    P     P     +P       R GSP +  P  GR  A+   G  
Sbjct: 1009 APGASGDRGPPGPVGPPGLTGP---AGEPG------REGSPGADGPP-GRDGAAGVKG-- 1056

Query: 187  RQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRA 246
                  D   T        A+G+   PG         P G+      TG Q  R      
Sbjct: 1057 ------DRGETG-------AVGAPGAPG---------PPGSPGPAGPTGKQGDRGEAGAQ 1094

Query: 247  PGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEG--GERGTEMLRRLRGSPRPNRHP 304
              +    +G +  R   G  G PR  K  AG  G+ G  G RG   L+ L G P      
Sbjct: 1095 GPMG--PSGPAGARGIQGPQG-PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP------ 1145

Query: 305  RSGPVPAHGVASAAAGPATLRAPPG 329
              GP    G AS  AGP+  R PPG
Sbjct: 1146 --GPSGDQG-ASGPAGPSGPRGPPG 1167



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 34/105 (32%), Positives = 41/105 (39%), Gaps = 10/105 (9%)

Query: 13   LAAGAGQAWGSAGRGRRGPAPR-GQTGTQGVG--SGGSGAGVRPEPCAGQRPAGGKALRG 69
            L   AG+       G  GP  R G  G +G    +G  GA   P P     PAG    +G
Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086

Query: 70   EGQAQAAQGYAAANG-WGTVLVSGLVPQDPRA----APPPGGRQL 109
            +     AQG    +G  G   + G  PQ PR     A  PG R L
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQG--PQGPRGDKGEAGEPGERGL 1129


>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 113/445 (25%), Positives = 148/445 (33%), Gaps = 80/445 (17%)

Query: 2   RGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTG---TQGVGSGGSGAGVRPEPCAG 58
           R  RA    L  A  A    G+   G  GPAP        TQ   SGG G G    P AG
Sbjct: 109 RSRRAAGPGLDCAGSAPAPSGAQSCG--GPAPASALRRPLTQWDASGGGGRGSHSGPRAG 166

Query: 59  QRPAGGKALRG----------------EGQAQAAQGYAAANGWGTVLVSGLVPQDPRA-- 100
             P GG++ R                 +G ++  QG  ++  WG    SG  P  PRA  
Sbjct: 167 -TPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSS--WGG---SG-TPPPPRALW 219

Query: 101 ---APPPGGRQLLLLRPPRWVP-SCFPNSQ--SADISQEDRKPAKRRPTHFYHPDEHKAQ 154
                  G R  +     R  P S  P S   +  +    R     +   F  P  H   
Sbjct: 220 NRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTS 279

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPG 214
                G R  G   S  P +  S A+  + +P   +A    P+  A   RL  G  +   
Sbjct: 280 -----GGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTV 334

Query: 215 RRLALHLQV-------PEGARQLGPRTGAQP-SRHRRQRAPGLALVVTGVSRIRPAHGAP 266
            + A+   +       P   R L P  G++  +R  R      A  +   SR RP   AP
Sbjct: 335 LKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAP 394

Query: 267 GLPRAPKPSAGRGGKEGGER--------------GTEMLRRLRGSPRPNRHPRSGPVPAH 312
                P    G GG  G  +              GT  L   RGS  P        VP  
Sbjct: 395 RGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHF 454

Query: 313 GVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRA-PSIARSLP----- 366
              S+ A  +  R+P  R            L + R + PQ  R  A P IA   P     
Sbjct: 455 RPLSSPAPQSPPRSPSVRAFG-------PRLGAGRLSCPQAPRAAALPGIAVLAPSPAHD 507

Query: 367 -GSGRLQGL---IFPSTGKNVQRHK 387
            G  R +G      P  G+  +R K
Sbjct: 508 WGGQRCEGCGGGSQPFAGRRAERGK 532


>gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 113/445 (25%), Positives = 148/445 (33%), Gaps = 80/445 (17%)

Query: 2   RGLRACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTG---TQGVGSGGSGAGVRPEPCAG 58
           R  RA    L  A  A    G+   G  GPAP        TQ   SGG G G    P AG
Sbjct: 109 RSRRAAGPGLDCAGSAPAPSGAQSCG--GPAPASALRRPLTQWDASGGGGRGSHSGPRAG 166

Query: 59  QRPAGGKALRG----------------EGQAQAAQGYAAANGWGTVLVSGLVPQDPRA-- 100
             P GG++ R                 +G ++  QG  ++  WG    SG  P  PRA  
Sbjct: 167 -TPGGGRSSRAGARRKTPLSLCPLKLRKGSSRRCQGLGSS--WGG---SG-TPPPPRALW 219

Query: 101 ---APPPGGRQLLLLRPPRWVP-SCFPNSQ--SADISQEDRKPAKRRPTHFYHPDEHKAQ 154
                  G R  +     R  P S  P S   +  +    R     +   F  P  H   
Sbjct: 220 NRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTS 279

Query: 155 PSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPG 214
                G R  G   S  P +  S A+  + +P   +A    P+  A   RL  G  +   
Sbjct: 280 -----GGRPTGERSSREPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTV 334

Query: 215 RRLALHLQV-------PEGARQLGPRTGAQP-SRHRRQRAPGLALVVTGVSRIRPAHGAP 266
            + A+   +       P   R L P  G++  +R  R      A  +   SR RP   AP
Sbjct: 335 LKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAP 394

Query: 267 GLPRAPKPSAGRGGKEGGER--------------GTEMLRRLRGSPRPNRHPRSGPVPAH 312
                P    G GG  G  +              GT  L   RGS  P        VP  
Sbjct: 395 RGSAPPARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHF 454

Query: 313 GVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRA-PSIARSLP----- 366
              S+ A  +  R+P  R            L + R + PQ  R  A P IA   P     
Sbjct: 455 RPLSSPAPQSPPRSPSVRAFG-------PRLGAGRLSCPQAPRAAALPGIAVLAPSPAHD 507

Query: 367 -GSGRLQGL---IFPSTGKNVQRHK 387
            G  R +G      P  G+  +R K
Sbjct: 508 WGGQRCEGCGGGSQPFAGRRAERGK 532


>gi|13129104 coiled-coil domain containing 86 [Homo sapiens]
          Length = 360

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 57/231 (24%), Positives = 90/231 (38%), Gaps = 37/231 (16%)

Query: 156 SHVRGSRRPGSPRS---ASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARG 212
           S+   +R PGSP S   A  G       +  G PR      L      P+       A  
Sbjct: 37  SNPEETREPGSPPSVQRAGLGSPERPPKTSPGSPRLQQGAGLESPQGQPEP-----GAAS 91

Query: 213 PGRRLALHLQVPEGARQLGP---RTGAQPSRHRRQRAPGLALVVTGVSRIR-------PA 262
           P R+  LHL+ P+   +  P   R   +PS    + +    ++ + +++ +       P 
Sbjct: 92  PQRQQDLHLESPQRQPEYSPESPRCQPKPSEEAPKCSQDQGVLASELAQNKEELTPGAPQ 151

Query: 263 HGAPGLPRAPKPSAGRG--GKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAG 320
           H  P +P +P+P  G+   G E  +   E+  R  GSPR  +H  S P PA    +   G
Sbjct: 152 HQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGSPR-GQHEPSKPPPAGETVTGGFG 210

Query: 321 PATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRL 371
                A   +G+SS+             A  +  +   P I +  P SGR+
Sbjct: 211 -----AKKRKGSSSQA-----------PASKKLNKEELPVIPKGKPKSGRV 245


>gi|239747641 PREDICTED: hypothetical protein XP_002347916 [Homo
           sapiens]
          Length = 193

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/158 (30%), Positives = 56/158 (35%), Gaps = 37/158 (23%)

Query: 219 LHLQVP----EGARQLGPRTGAQPSRHRRQ------RAPGLALVVTGVSRIRPAHGAPGL 268
           L LQVP    EG   L  +   +P + +RQ      R+P  A     V  +R     P  
Sbjct: 35  LQLQVPLSGAEGKELLAAQAAHRPRQQQRQQQRPRPRSPDPAARGQHVPELRSRKPGPAA 94

Query: 269 ---------------PRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHG 313
                          P  P P     G  GGER  E     R  PRP   PR  P+ A G
Sbjct: 95  RTEEGGDVTGRPWQPPLLPPPGVPTPGNRGGERRGER----RAPPRPAGAPRGSPMAARG 150

Query: 314 VASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPP 351
            A   A P  L    G GA      P     S+R APP
Sbjct: 151 RARGEAEPPAL----GAGACDSRNQP----DSQRTAPP 180


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 69/266 (25%), Positives = 86/266 (32%), Gaps = 48/266 (18%)

Query: 94   VPQDPRAAPPPGGRQLL-------LLRPPRWVPSCFPNSQSADISQED------RKPAKR 140
            +P  P A PPP     L       L  PP   P   P S SA +          + P   
Sbjct: 776  LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835

Query: 141  RPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKA 200
                   P    A P+ ++  RRP +P   +   G     + A  P  P +     T   
Sbjct: 836  AAPLLQVPPSPPASPT-LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 894

Query: 201  PDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQ-----PSRHRRQRAPGLALVVTG 255
            PD      SA      L  +   PEG     P   A+     P+   R  AP LA     
Sbjct: 895  PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF---- 950

Query: 256  VSRIRPAHGAPGLPRAPKPSAGRGGKEG-----GERGTEMLRRLRGSPRPNRHPRSGPVP 310
                    GAPG P    P+ G G  +G        G E      G+  P      GP P
Sbjct: 951  -------RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP------GPSP 997

Query: 311  AHGVASAAAGPATLRAPPGRGASSET 336
                  AAAG        G GASS +
Sbjct: 998  GTSGGKAAAG-------AGAGASSRS 1016



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 48/165 (29%), Positives = 64/165 (38%), Gaps = 30/165 (18%)

Query: 245 RAPGLALVVTGVSRIRPAHGAPGLPRAPKPSA-------GRGGKEGGERGTEMLRRLRGS 297
           RAPGL          RP    PG PR P P         G  G  G +   E    + G+
Sbjct: 20  RAPGLLTP-------RP----PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68

Query: 298 PRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTR 357
             P   PR+GP  + G +S    PA+     GRG   E   P +N S    + P R    
Sbjct: 69  TIPESAPRAGPTRSAGTSS--RNPASRPPASGRG---ERAPPAKNTSPGPVSSPGR---- 119

Query: 358 APSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402
             +   + PG    +GL   S  + V R K+   P   +LS  +R
Sbjct: 120 --ASGTTRPGPLGQKGLRI-SAEETVARGKATEAPKRSALSAGAR 161



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 88/400 (22%), Positives = 139/400 (34%), Gaps = 47/400 (11%)

Query: 13  LAAGAGQAWGSAGRGRRGPAPRGQTGTQG----VGSGGSGAGVRPEPCAGQRP-AGGKAL 67
           +A  +  A    G  R  P+ R +  T+G    V S    +   P P A +RP AGG   
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235

Query: 68  RGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVP------SC 121
           R   ++ ++     ++   +   +   P+ P     P  + L  LRPP+  P        
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295

Query: 122 FPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASS 181
                S+ ++       K RP     P ++ A P     +  P SP  A+P         
Sbjct: 296 LGPLSSSPLATPSPSGTKARPV---PPPDNAATP---LPATLPPSPPLATP--------- 340

Query: 182 WAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRH 241
              +P  P +    P+ +   +  A   ++ P       +Q P   + + P         
Sbjct: 341 ---LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 242 RRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPN 301
              +AP   L ++ + +   + G+P L       A         R T+    L    RP 
Sbjct: 398 PSLQAPPSPLALSSL-QATTSLGSPTL------QATHSFLTMSPRQTQ--ASLTSPSRPA 448

Query: 302 RHPRSGPVPAHGVASAAAGP--ATLRAPPGRGASSE-TMWPTENLSSRRRAPPQRRRTRA 358
             P   P P     S  A P   T  +P     SS  T+ P + LSS     PQ     A
Sbjct: 449 STPPDSP-PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ-----A 502

Query: 359 PSIARSLPGSGRLQGLIFPSTGKNVQRHKSPPLPSEESLS 398
           P  +  +P       L  PS         +PPL +  SL+
Sbjct: 503 PLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 75/308 (24%), Positives = 94/308 (30%), Gaps = 58/308 (18%)

Query: 95  PQDPRAAPPPGGRQLLLLRPPRWVPS---------------CFPNSQSADISQEDRKPAK 139
           P  P A PPP     L L P +  PS                 PN+ +  + Q    P  
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669

Query: 140 RRPTH--FYHPDEHKAQPSHVRGSRRPGS----PRSASPGVGRSWASSWAGVP------- 186
             P    F  P      PS    S+ P S    P    P    S   S +  P       
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729

Query: 187 --RQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQ 244
               PL +   P    P +  A    R P    A  LQVP       P +   P      
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS---PLAKPPP 786

Query: 245 RAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHP 304
           +AP             PA   P L   P P A   G+            L  SP     P
Sbjct: 787 QAP-------------PALATPPLQALPSPPASFPGQAPFSPSAS----LPMSPLATPPP 829

Query: 305 RSGPVPAHGVASAAAGP---ATLRA---PPGRGASSETMWPTENLSSRRRAPPQRRRTRA 358
           ++ PV A  +      P    TL+A   PP  G  +    P   L+     PP    +R+
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP--PSRS 887

Query: 359 PSIARSLP 366
           PS   S P
Sbjct: 888 PSSTLSGP 895


>gi|51093859 calcium channel, voltage-dependent, T type, alpha 1I
            subunit isoform b [Homo sapiens]
          Length = 2188

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 65/271 (23%), Positives = 92/271 (33%), Gaps = 49/271 (18%)

Query: 117  WVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGR 176
            W+      +  +  S +   P    P  F+HP    +Q    +G+     P+ A  G   
Sbjct: 1901 WLKHDSSQAPPSPFSPDASSPLLPMPAEFFHPAVSASQKGPEKGTGTGTLPKIALQG--- 1957

Query: 177  SWASSWAGVPR-----------QPLALDLRPTWKAPDARLALGS----ARGPGRRLALHL 221
            SWAS  +  PR              +LD  P+  A   +  L      +  P R L    
Sbjct: 1958 SWASLRS--PRVNCTLLRQATGSDTSLDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPA 2015

Query: 222  QVPEGARQLGPRTGAQPSRHRRQRAPGLALV-VTGVSRIRPAHGAPGLPRA--------- 271
              P      GPR G  P+  RR    G  L  + G+   + +H + G             
Sbjct: 2016 PAP------GPRAGLSPAARRRLSLRGRGLFSLRGLRAHQRSHSSGGSTSPGCTHHDSMD 2069

Query: 272  PKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLR-APPGR 330
            P    GRGG  GG  G+E    L      +      P PA G+  A    +T   A PGR
Sbjct: 2070 PSDEEGRGGAGGGGAGSEHSETLSSLSLTSLFCPPPPPPAPGLTPARKFSSTSSLAAPGR 2129

Query: 331  --------GASSETMWPTENLSSRRRAPPQR 353
                    G +    W  +    R + PP R
Sbjct: 2130 PHAAALAHGLARSPSWAAD----RSKDPPGR 2156


>gi|21361077 calcium channel, voltage-dependent, T type, alpha 1I
            subunit isoform a [Homo sapiens]
          Length = 2223

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 65/271 (23%), Positives = 92/271 (33%), Gaps = 49/271 (18%)

Query: 117  WVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGR 176
            W+      +  +  S +   P    P  F+HP    +Q    +G+     P+ A  G   
Sbjct: 1936 WLKHDSSQAPPSPFSPDASSPLLPMPAEFFHPAVSASQKGPEKGTGTGTLPKIALQG--- 1992

Query: 177  SWASSWAGVPR-----------QPLALDLRPTWKAPDARLALGS----ARGPGRRLALHL 221
            SWAS  +  PR              +LD  P+  A   +  L      +  P R L    
Sbjct: 1993 SWASLRS--PRVNCTLLRQATGSDTSLDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPA 2050

Query: 222  QVPEGARQLGPRTGAQPSRHRRQRAPGLALV-VTGVSRIRPAHGAPGLPRA--------- 271
              P      GPR G  P+  RR    G  L  + G+   + +H + G             
Sbjct: 2051 PAP------GPRAGLSPAARRRLSLRGRGLFSLRGLRAHQRSHSSGGSTSPGCTHHDSMD 2104

Query: 272  PKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLR-APPGR 330
            P    GRGG  GG  G+E    L      +      P PA G+  A    +T   A PGR
Sbjct: 2105 PSDEEGRGGAGGGGAGSEHSETLSSLSLTSLFCPPPPPPAPGLTPARKFSSTSSLAAPGR 2164

Query: 331  --------GASSETMWPTENLSSRRRAPPQR 353
                    G +    W  +    R + PP R
Sbjct: 2165 PHAAALAHGLARSPSWAAD----RSKDPPGR 2191


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 86/322 (26%), Positives = 106/322 (32%), Gaps = 63/322 (19%)

Query: 13  LAAGAGQAWGSAGRGRRG-PAPRGQTGTQGV-GSGGSGAGVRPEPCAGQRPAGGKALRGE 70
           L   AG       RG  G P P G  GT G  GS G+   V P    G   A G+  RGE
Sbjct: 313 LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQ--RGE 370

Query: 71  GQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADI 130
                 QG+A A G          P  P     PGG+  +    P  +P   P    A  
Sbjct: 371 ---PGPQGHAGAQG---------PPGPPGINGSPGGKGEM---GPAGIPGA-PGLMGA-- 412

Query: 131 SQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPL 190
                    R P     P      P    G+  PG    A    G       AG+P  P 
Sbjct: 413 ---------RGPPG---PAGANGAPGLRGGAGEPGK-NGAKGEPGPRGERGEAGIPGVPG 459

Query: 191 ALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLA 250
           A        +P    A G     G R A   + P G   +    G    R          
Sbjct: 460 AKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGER---------- 509

Query: 251 LVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSP-RPNRHPRSGPV 309
                        GAPG P  P+ +AG  G++G   G  M R + GSP  P    + GP 
Sbjct: 510 -------------GAPG-PAGPRGAAGEPGRDGVPGGPGM-RGMPGSPGGPGSDGKPGPP 554

Query: 310 PAHGVAS--AAAGPATLRAPPG 329
            + G +      GP+  R  PG
Sbjct: 555 GSQGESGRPGPPGPSGPRGQPG 576



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 93/373 (24%), Positives = 123/373 (32%), Gaps = 60/373 (16%)

Query: 46  GSGAGVRPEP-CAGQRPAGGKALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPP 104
           G    V P+P  A  RP  G+  +G        G    NG         +P  P +   P
Sbjct: 82  GECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNG------DPGIPGQPGSPGSP 135

Query: 105 GGRQLLLLRPPRWVPSC--FPNSQSADISQEDRKP--AKRRPTHFYHPDEHKAQPSHVRG 160
           G        PP    SC   P + S      D K   A      +  P      P     
Sbjct: 136 G--------PPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT 187

Query: 161 SRRPGSPRSASPGV----GRSWASSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRR 216
           S  PGSP   SPG     G    +  +G P  P A+   P+  A       G +  PGR 
Sbjct: 188 SGHPGSP--GSPGYQGPPGEPGQAGPSGPPGPPGAIG--PSGPAGKD----GESGRPGRP 239

Query: 217 LALHLQVPEGARQLGPRTGAQPSRHRR-----------QRAPGLALVVTGVSRIRPAHGA 265
               L  P G +      G    +  R             APGL     G + +   +GA
Sbjct: 240 GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLK----GENGLPGENGA 295

Query: 266 PGLPRAPKPSAGRGGKEG-----GERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAG 320
           PG P  P+ + G  G+ G     G RG +  R   G P P   P +   P    A    G
Sbjct: 296 PG-PMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVG 354

Query: 321 PATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTG 380
           PA   +P   GA  +   P     +  + PP       P I  S  G G +     P   
Sbjct: 355 PA--GSPGSNGAPGQRGEPGPQGHAGAQGPP-----GPPGINGSPGGKGEMGPAGIPG-A 406

Query: 381 KNVQRHKSPPLPS 393
             +   + PP P+
Sbjct: 407 PGLMGARGPPGPA 419



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 92/347 (26%), Positives = 112/347 (32%), Gaps = 50/347 (14%)

Query: 17  AGQAWGSAGRGRRG-PAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQA 75
           AG    +   G+RG P P+G  G QG   G  G    P       PAG     G   A+ 
Sbjct: 356 AGSPGSNGAPGQRGEPGPQGHAGAQGP-PGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414

Query: 76  AQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSAD------ 129
             G A ANG   +      P    A   PG R     R    +P   P ++  D      
Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE---RGEAGIPGV-PGAKGEDGKDGSP 470

Query: 130 ----------ISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWA 179
                      + E   P  R P         K  P+  RG+  P  PR A+   GR   
Sbjct: 471 GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKG-PAGERGAPGPAGPRGAAGEPGRD-- 527

Query: 180 SSWAGVPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPR----TG 235
               GVP  P    +R    +P    + G    PG +       P G    GPR      
Sbjct: 528 ----GVPGGP---GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS--GPRGQPGVM 578

Query: 236 AQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGL-----PRAPKPSAGRGGKEG-----GE 285
             P       APG      G     P  G PG      P+ P    G GG +G     G 
Sbjct: 579 GFPGPKGNDGAPGKNGERGGPGGPGP-QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGP 637

Query: 286 RGTEMLRRLRGSPRPNRHP-RSGPVPAHGVASAAAGPATLRAPPGRG 331
           +G + L    G P  N  P   GP    G   A  G     AP  RG
Sbjct: 638 QGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERG 684



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 90/366 (24%), Positives = 115/366 (31%), Gaps = 59/366 (16%)

Query: 14   AAGAGQAWGSAGR--GRRGPAPRGQTGTQGVGSGGSGA----GVRPE--PCAGQRPAGGK 65
            AAG     G  G   G   P P+G  G  G G G  G     G R    P     PAG  
Sbjct: 718  AAGTPGLQGMPGERGGLGSPGPKGDKGEPG-GPGADGVPGKDGPRGPTGPIGPPGPAGQP 776

Query: 66   ALRGEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNS 125
              +GEG A    G A   G          P +     PPG             P+ FP +
Sbjct: 777  GDKGEGGAPGLPGIAGPRG---------SPGERGETGPPG-------------PAGFPGA 814

Query: 126  --QSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWA 183
              Q+ +   +  + A         P    A P    G   P  P+      G       A
Sbjct: 815  PGQNGEPGGKGERGAPGEKGEGGPPG--VAGPPGGSGPAGPPGPQGVKGERGSPGGPGAA 872

Query: 184  GVPRQ-----PLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGA-- 236
            G P       P   +  P    P          GP    A +   P      GP+  A  
Sbjct: 873  GFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGP----AGNTGAPGSPGVSGPKGDAGQ 928

Query: 237  -----QPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEG--GERGTE 289
                  P       APG  L + G++  R   G PG+P  P+ S G  G +G  G+ G  
Sbjct: 929  PGEKGSPGAQGPPGAPG-PLGIAGITGARGLAGPPGMP-GPRGSPGPQGVKGESGKPGAN 986

Query: 290  MLRRLRGSPRPNRHP----RSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSS 345
             L   RG P P   P     +G     G   +   P    +P G+G   E   P    + 
Sbjct: 987  GLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAP 1046

Query: 346  RRRAPP 351
                PP
Sbjct: 1047 GHPGPP 1052



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 98/368 (26%), Positives = 121/368 (32%), Gaps = 80/368 (21%)

Query: 22   GSAG-RGRRG-PAPRGQTGTQGVG--SGGSGAGVRPEPCAG---------QRPAGGKALR 68
            G+AG  G RG P P G  G  G    SG  G    P P              P G     
Sbjct: 870  GAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQP 929

Query: 69   GEGQAQAAQGYAAANGWGTVLVSGLVPQDPRAAPP--PGGRQLLLLRPPRWVPSCFPNSQ 126
            GE  +  AQG   A G   + ++G+      A PP  PG             P   P  Q
Sbjct: 930  GEKGSPGAQGPPGAPG--PLGIAGITGARGLAGPPGMPG-------------PRGSPGPQ 974

Query: 127  SADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVP 186
               +  E  KP     +    P   +  P     +  PG  R  +PG          G+P
Sbjct: 975  G--VKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG--RDGNPGSD--------GLP 1022

Query: 187  RQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRA 246
             +    D  P  K    R   GS   PG         P      GP   A  S  R +  
Sbjct: 1023 GR----DGSPGGKGD--RGENGSPGAPG--------APGHPGPPGPVGPAGKSGDRGESG 1068

Query: 247  PGLALVVTGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSP-RPNRHPR 305
            P       G +  R   GAPG P+ P+   G    E GERG   ++  RG P  P     
Sbjct: 1069 PAGPAGAPGPAGSR---GAPG-PQGPRGDKG----ETGERGAAGIKGHRGFPGNPGAPGS 1120

Query: 306  SGPVPAHGVASAAAGPATLR------APPGRGASSETMWPTENLSSRRRAPPQRRRTRAP 359
             GP    G A  + GPA  R       PPG+  +S    P          PP  R  R  
Sbjct: 1121 PGPAGQQG-AIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPI--------GPPGPRGNRGE 1171

Query: 360  SIARSLPG 367
              +   PG
Sbjct: 1172 RGSEGSPG 1179


>gi|169173182 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 255

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 51/184 (27%), Positives = 70/184 (38%), Gaps = 35/184 (19%)

Query: 160 GSRRPGSPRSASPGVGRSWASSWAGVPRQPLAL--DLRPTWKAPDARLALGSARGPGRRL 217
           G+    +PR A P +GR WA+  A  P   + L   LR    + D    L +   P +  
Sbjct: 69  GNAESPAPRRARPDLGRPWATRSAASPHSKMWLGSHLRGGEMSGDPHTDLPA--HPAQTT 126

Query: 218 ALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPGLPRAPKPSAG 277
              L++P    Q  P   ++P       AP            RPAH      ++P     
Sbjct: 127 NPELELPADPAQPDPAPLSRP-------APP-----------RPAH------QSPAEEGP 162

Query: 278 RGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETM 337
           RG   GG R T    R +G   P   PR+ P       SAA   A++R P   GA+    
Sbjct: 163 RGAAGGGPR-TPPAGRTQGQSGPRESPRASP------GSAAPAMASVRGPARDGATRSEP 215

Query: 338 WPTE 341
             TE
Sbjct: 216 HATE 219



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 44/168 (26%), Positives = 54/168 (32%), Gaps = 34/168 (20%)

Query: 98  PRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPT--------HFYHPD 149
           PR AP P    LL LRP        P +  A  + E   P + RP             P 
Sbjct: 47  PRRAPEP---PLLTLRPR-------PGTLRAPGNAESPAPRRARPDLGRPWATRSAASPH 96

Query: 150 EHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALGS 209
                 SH+RG    G P +  P       +    +P  P   D  P  +    R A  S
Sbjct: 97  SKMWLGSHLRGGEMSGDPHTDLPAHPAQTTNPELELPADPAQPDPAPLSRPAPPRPAHQS 156

Query: 210 ARGPGRRLALHLQVPEGARQLGPRT-------GAQPSRHRRQRAPGLA 250
               G         P GA   GPRT       G    R   + +PG A
Sbjct: 157 PAEEG---------PRGAAGGGPRTPPAGRTQGQSGPRESPRASPGSA 195


>gi|57222570 codanin 1 [Homo sapiens]
          Length = 1227

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 35/98 (35%), Positives = 45/98 (45%), Gaps = 8/98 (8%)

Query: 304 PRSGPVPAHGVASAAAGPATLRAPP--GRGASSETMWPTENLSSRRRAPPQRR--RTRAP 359
           P+  P PA    ++AA P     PP   RGA S+   PTE  S+   AP  RR  R R P
Sbjct: 66  PQGPPTPAKTPGASAALPGRPGGPPRGSRGARSQLFPPTEAQSTAAEAPLARRGGRRRGP 125

Query: 360 SIARSLPGSGRLQGLIFPST----GKNVQRHKSPPLPS 393
             AR   G G  +G+   S     G+ ++   SP  PS
Sbjct: 126 GPARERGGRGLEEGVSGESLPGAGGRRLRGSGSPSRPS 163



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 8/47 (17%)

Query: 25  GRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEG 71
           G  RRGP P  + G +G+  G SG     E   G   AGG+ LRG G
Sbjct: 119 GGRRRGPGPARERGGRGLEEGVSG-----ESLPG---AGGRRLRGSG 157


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 79/320 (24%), Positives = 107/320 (33%), Gaps = 42/320 (13%)

Query: 26  RGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGW 85
           RG+  P+PR    +QG G   +G             AG +  R   + ++    +A    
Sbjct: 359 RGKESPSPRSAPSSQGRGGRAAGG------------AGRRRRRRRRRRRSRSSASAPRRR 406

Query: 86  GTVLVSGLVPQDPRAAPPPG-GRQLLLLRPP------RWVPSCFPNSQSADISQEDRKPA 138
           G         + PR APP G  R L   R        R  P   P   S        K A
Sbjct: 407 GR--------RRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRA 458

Query: 139 KRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGV-GRSWASSWAGVPRQPLALDLRP- 196
           K RP          +  +H R     G   S SPG   RSW+SS +    +  + + RP 
Sbjct: 459 KERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPH 518

Query: 197 -TWKAPDARLALGSAR-GPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVT 254
              ++P  +  L   + G GR  A H +  E  R         P R RR+ +P       
Sbjct: 519 SPSRSPSPKKPLSRDKDGEGR--ARHSEA-EATRARRRSRSYSPIRKRRRDSPSF----M 571

Query: 255 GVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGV 314
              RI  A   P     P PS+               R    SP P     S    +HG 
Sbjct: 572 EPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSR----SPSPGHSHGSYSSRSHGT 627

Query: 315 ASAAAGPATLRAPPGRGASS 334
            S    P+   +P     SS
Sbjct: 628 RSRTRSPSRTPSPSYHSRSS 647



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 67/286 (23%), Positives = 92/286 (32%), Gaps = 42/286 (14%)

Query: 137 PAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRP 196
           P +R   H        +  SH   SR P          GR   S  +   R P       
Sbjct: 248 PGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSP------- 300

Query: 197 TWKAPDARLALGSAR---GPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVV 253
              +P      GS +   G G+R   H   P G+    P   + PS   R +A   A   
Sbjct: 301 ---SPSGGSGWGSPQRNGGSGQRSGAHGGRP-GSAHSPPDKPSSPSPRVRDKAAAAAPTP 356

Query: 254 TGVSRIRPAHGAPGLPRAPKPSAGRGGKEGGERGTEMLRRLRGS---------------- 297
               +  P+      PR+   S GRGG+  G  G    RR R                  
Sbjct: 357 PARGKESPS------PRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRR 410

Query: 298 PRPNRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTR 357
           PRP     S    +   +S+ +G       PG    SE         ++ R P  R  + 
Sbjct: 411 PRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAST 470

Query: 358 APSIARSLPGS-GRLQGLIFPSTGKNVQRHKSPPLPSEESLSQRSR 402
           +PS     PG+ GR  G    S+ ++   H      S      RSR
Sbjct: 471 SPS-----PGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSR 511



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 67/265 (25%), Positives = 89/265 (33%), Gaps = 45/265 (16%)

Query: 125 SQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAG 184
           S+S+   ++++   K+RP        H   P   R S R  S  S SP +   ++ S   
Sbjct: 226 SRSSKCKRKEKNKEKKRP--------HTESPG--RRSHRHSSGSSHSPSLSSHYSDS--- 272

Query: 185 VPRQPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQ 244
             R P  L  +               R  GR+     Q   G+R   P  G+     +R 
Sbjct: 273 --RSPSRLSPKH--------------RDEGRKTGS--QRSSGSRSPSPSGGSGWGSPQRN 314

Query: 245 RAPGLALVVTGVSRIRPAHGAPGLPRAPKP----SAGRGGKEGGERGTEMLRRLRGSPRP 300
              G      G  R   AH  P  P +P P     A         RG E       SP P
Sbjct: 315 GGSGQRSGAHG-GRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKE-------SPSP 366

Query: 301 NRHPRSGPVPAHGVASAAAGPATLRAPPGRGASSETMWPTENLSSRRRAPPQRRRTRAPS 360
              P S      G A+  AG    R    R + S    P      R R  P R  +R+ S
Sbjct: 367 RSAPSSQG--RGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLS 424

Query: 361 IARSLPGSGRLQGLIFPSTGKNVQR 385
            ARS   SG  +G   P      +R
Sbjct: 425 RARSSSDSGSGRGAPGPGPEPGSER 449


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 80/365 (21%), Positives = 114/365 (31%), Gaps = 51/365 (13%)

Query: 29  RGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAAANGWGTV 88
           +GP P+G    QG    G   G  P+   G +    ++  G+ Q    QG     G    
Sbjct: 79  QGPPPQGGNKPQGPPPPGKPQGPPPQ---GDKSRSPRSPPGKPQGPPPQGGNQPQG---- 131

Query: 89  LVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPTHFYHP 148
                 P  P+  PP GG +     PP       P  Q  + S+  R P  +       P
Sbjct: 132 --PPPPPGKPQGPPPQGGNKPQGPPPPGKPQG--PPPQGDNKSRSSRSPPGKPQGP---P 184

Query: 149 DEHKAQPSHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPDARLALG 208
            +   QP        PG P+   P  G          P +P     +   K+  AR   G
Sbjct: 185 PQGGNQPQGPPPP--PGKPQGPPPQGGNK--PQGPPPPGKPQGPPPQGDNKSQSARSPPG 240

Query: 209 SARGP---GRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGA 265
             +GP   G         P G  Q  P  G    +              G S+ R +   
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300

Query: 266 PGLPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLR 325
           PG P+ P P  G               + +G P P   P+  P            P   +
Sbjct: 301 PGKPQGPPPQGG--------------NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 346

Query: 326 APPGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARSLPGSGRLQGLIFPSTGKNVQR 385
            PP +G S          S   R+PP + +        +  G         P  G N Q+
Sbjct: 347 GPPPQGGSK---------SRSARSPPGKPQGPPQQEGNNPQGPP-------PPAGGNPQQ 390

Query: 386 HKSPP 390
            ++PP
Sbjct: 391 PQAPP 395



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 66/307 (21%), Positives = 99/307 (32%), Gaps = 66/307 (21%)

Query: 93  LVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHK 152
           L+  +P+ APP GG +      P+  PS  P        Q   +P    P     P + +
Sbjct: 31  LIAGNPQGAPPQGGNK------PQGPPSP-PGKPQGPPPQGGNQPQGPPPP----PGKPQ 79

Query: 153 AQP----SHVRGSRRPGSPRSASPGVGRSWASSWAGVPRQPLALDLRPTWKAPD-ARLAL 207
             P    +  +G   PG P+   P   +S         R P +   +P    P       
Sbjct: 80  GPPPQGGNKPQGPPPPGKPQGPPPQGDKS---------RSPRSPPGKPQGPPPQGGNQPQ 130

Query: 208 GSARGPGRRLALHLQVPEGARQLGPRTGAQPSRHRRQRAPGLALVVTGVSRIRPAHGAPG 267
           G    PG+        P+G    G      P    + + P       G ++ R +   PG
Sbjct: 131 GPPPPPGK--------PQGPPPQGGNKPQGPPPPGKPQGP----PPQGDNKSRSSRSPPG 178

Query: 268 LPRAPKPSAGRGGKEGGERGTEMLRRLRGSPRPNRHPRSGPVPAHGVASAAAGPATLRAP 327
            P+ P P  G               + +G P P   P+  P            P   + P
Sbjct: 179 KPQGPPPQGG--------------NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 224

Query: 328 PGRGASSETMWPTENLSSRRRAPPQRRRTRAPSIARS----LPGSGRLQGLIFPSTGKNV 383
           P +G         +N S   R+PP + +   P          P  G+ QG   P  G N 
Sbjct: 225 PPQG---------DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP--PPQGGNK 273

Query: 384 QRHKSPP 390
            +   PP
Sbjct: 274 PQGPPPP 280



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 37/152 (24%), Positives = 48/152 (31%), Gaps = 32/152 (21%)

Query: 22  GSAGRGRRGPAPRGQTGTQGVGSGGSGAGVRPEPCAGQRPAGGKALRGEGQAQAAQGYAA 81
           GS  R  R P  + Q                P P  G +P G     G+ Q    QG   
Sbjct: 291 GSKSRSSRSPPGKPQ---------------GPPPQGGNQPQGPPPPPGKPQGPPPQG--- 332

Query: 82  ANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLRPPRWVPSCFPNSQSADISQEDRKPAKRR 141
               G        P  P+  PP GG +    R P       P        QE   P    
Sbjct: 333 ----GNKPQGPPPPGKPQGPPPQGGSKSRSARSP-------PGKPQGPPQQEGNNPQGPP 381

Query: 142 PTHFYHPDEHKAQPS-HVRGSRRPGSPRSASP 172
           P    +P + +A P+   +G  RP  P+   P
Sbjct: 382 PPAGGNPQQPQAPPAGQPQGPPRP--PQGGRP 411


>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
           [Homo sapiens]
          Length = 828

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 94/328 (28%), Positives = 124/328 (37%), Gaps = 64/328 (19%)

Query: 5   RACSRDLRLAAGAGQAWGSAGRGRRGPAPRGQTGT----QGVGSGGSGAGVRPEPCAGQR 60
           RA S   R   GAG + G A   R GP P  Q G       +G  GS  G    P A + 
Sbjct: 137 RATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRG---SPLA-EG 192

Query: 61  PAGGKALRGEGQAQAAQGY-AAANGWGTVLVSGLVPQDPRAAPPPGGRQLLLLR---PPR 116
           P      RG      A  Y A A+ +G+ L+          APP   +  L LR   P  
Sbjct: 193 PQAFFPERGPSPRPPATAYDAPASAFGSSLLGS---GGSAFAPPLRAQDDLTLRRRPPKA 249

Query: 117 WVPSCFPNSQSADISQEDRKPAKRRPTHFYHPDEHKAQPSHVRGSRRPGSPRSAS--PGV 174
           W      N    D++ E +KP++   T  Y   +  A+P+       P    S     G 
Sbjct: 250 W------NESDLDVAYE-KKPSQ---TASYERLDVFARPASPSLQLLPWRESSLDGLGGT 299

Query: 175 GRSWASSWAGVPR----QPLALDLRPTWKAPDARLALGSARGPGRRLALHLQVPEGARQL 230
           G+   +S A +PR     PLA D R    A   R +LGSA GP   L    Q    +R  
Sbjct: 300 GKDNLTS-ATLPRNYKVSPLASDRRS--DAGSYRRSLGSA-GPSGTLPRSWQ--PVSRIP 353

Query: 231 GPRTGAQPSRHRRQRAPGLALVVT--------GVSRIRPAHGAPGLPRAPKPSAGRGGKE 282
            P +  QP    RQR   L+++          G SR     G+P   RAP P        
Sbjct: 354 MPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAM-LPGSPLFTRAPPP-------- 404

Query: 283 GGERGTEMLRRLRGSPRPNRHPRSGPVP 310
                     +L+  P+P   P+S P P
Sbjct: 405 ----------KLQPQPQPQPQPQSQPQP 422


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,062,119
Number of Sequences: 37866
Number of extensions: 1475715
Number of successful extensions: 10203
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 954
Number of HSP's that attempted gapping in prelim test: 7712
Number of HSP's gapped (non-prelim): 3036
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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