Guide to the Human Genome
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Search of human proteins with 169172906

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169172906 PREDICTED: similar to defensin, beta 131 [Homo
sapiens]
         (70 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169172906 PREDICTED: similar to defensin, beta 131 [Homo sapi...   153   2e-38
gi|169173154 PREDICTED: hypothetical protein [Homo sapiens]           149   6e-37
gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo sapi...   149   6e-37
gi|149944551 defensin, beta 131 [Homo sapiens]                        146   3e-36
gi|169202989 PREDICTED: similar to defensin, beta 131 [Homo sapi...   145   5e-36
gi|169203494 PREDICTED: similar to defensin, beta 131 [Homo sapi...   145   5e-36
gi|169202282 PREDICTED: similar to defensin, beta 131 [Homo sapi...   145   5e-36
gi|239743495 PREDICTED: hypothetical protein XP_002342880 [Homo ...   144   2e-35
gi|23503331 defensin, beta 123 precursor [Homo sapiens]                35   0.010
gi|82734219 beta-defensin 114 [Homo sapiens]                           35   0.013
gi|18250304 beta defensin 129 precursor [Homo sapiens]                 32   0.11 
gi|22748611 defensin, beta 106A precursor [Homo sapiens]               31   0.24 
gi|103485143 defensin, beta 106B precursor [Homo sapiens]              31   0.24 
gi|103485139 defensin, beta 104A precursor [Homo sapiens]              30   0.41 
gi|103485137 defensin, beta 104B precursor [Homo sapiens]              30   0.41 
gi|16905373 beta-defensin 118 [Homo sapiens]                           29   0.70 
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]                28   2.0  
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]            27   3.5  
gi|195539372 ADAM metallopeptidase with thrombospondin type 1 mo...    27   4.5  
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]      27   4.5  
gi|74136827 beta-defensin 134 [Homo sapiens]                           26   5.9  
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]            26   7.7  

>gi|169172906 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  153 bits (387), Expect = 2e-38
 Identities = 70/70 (100%), Positives = 70/70 (100%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|169173154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 70

 Score =  149 bits (375), Expect = 6e-37
 Identities = 68/70 (97%), Positives = 68/70 (97%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          MRVLFFVFGVLSLMSTVPP RSFISNDECPSEYYHCRLKCNADEHAI YCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  149 bits (375), Expect = 6e-37
 Identities = 68/70 (97%), Positives = 68/70 (97%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          MRVLFFVFGVLSLMSTVPP RSFISNDECPSEYYHCRLKCNADEHAI YCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|149944551 defensin, beta 131 [Homo sapiens]
          Length = 70

 Score =  146 bits (369), Expect = 3e-36
 Identities = 67/70 (95%), Positives = 67/70 (95%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          MRVLFFVFGVLSLM TVPP RSFISNDECPSEYYHCRLKCNADEHAI YCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMFTVPPARSFISNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|169202989 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  145 bits (367), Expect = 5e-36
 Identities = 66/70 (94%), Positives = 67/70 (95%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          MRVLFFVFGVLSLMSTVPP RSF SNDECPSEYYHCRLKCNADEHAI YCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          II+IDGQKKW
Sbjct: 61 IIQIDGQKKW 70


>gi|169203494 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  145 bits (367), Expect = 5e-36
 Identities = 66/70 (94%), Positives = 67/70 (95%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          MRVLFFVFGVLSLMSTVPP RSF SNDECPSEYYHCRLKCNADEHAI YCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          II+IDGQKKW
Sbjct: 61 IIQIDGQKKW 70


>gi|169202282 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score =  145 bits (367), Expect = 5e-36
 Identities = 66/70 (94%), Positives = 67/70 (95%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          MRVLFFVFGVLSLMSTVPP RSF SNDECPSEYYHCRLKCNADEHAI YCADFSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          II+IDGQKKW
Sbjct: 61 IIQIDGQKKW 70


>gi|239743495 PREDICTED: hypothetical protein XP_002342880 [Homo
          sapiens]
          Length = 70

 Score =  144 bits (362), Expect = 2e-35
 Identities = 66/70 (94%), Positives = 66/70 (94%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          MRVLFFVFGVLSLMSTVPP RSFISNDECPSEYYHCRLKCNADEH I YCA FSICCKLK
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDECPSEYYHCRLKCNADEHVIRYCAYFSICCKLK 60

Query: 61 IIEIDGQKKW 70
          IIEIDGQKKW
Sbjct: 61 IIEIDGQKKW 70


>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
          Length = 67

 Score = 35.4 bits (80), Expect = 0.010
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 4/57 (7%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICC 57
          M++L     VL L+S + P         C + Y  CR +C+  E    YC +  +CC
Sbjct: 1  MKLLLLTLTVLLLLSQLTPG----GTQRCWNLYGKCRYRCSKKERVYVYCINNKMCC 53


>gi|82734219 beta-defensin 114 [Homo sapiens]
          Length = 69

 Score = 35.0 bits (79), Expect = 0.013
 Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCA-DFSICCKL 59
          MR+ +++  +  +   +P   + ++ D C   Y  C+  C   E  I  C+    ICC  
Sbjct: 1  MRIFYYLHFLCYVTFILPATCTLVNADRCTKRYGRCKRDCLESEKQIDICSLPRKICCTE 60

Query: 60 KIIEID 65
          K+ E D
Sbjct: 61 KLYEED 66


>gi|18250304 beta defensin 129 precursor [Homo sapiens]
          Length = 183

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 2/64 (3%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          M++LF +F  L L   V     FI    C      CR  CN DE  I  C     C   K
Sbjct: 1  MKLLFPIFASLMLQYQV--NTEFIGLRRCLMGLGRCRDHCNVDEKEIQKCKMKKCCVGPK 58

Query: 61 IIEI 64
          ++++
Sbjct: 59 VVKL 62


>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
          Length = 65

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 15/58 (25%), Positives = 26/58 (44%), Gaps = 3/58 (5%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCK 58
          MR   F+F VL  ++   P ++   +++C      C+  C  +E  I  C     CC+
Sbjct: 1  MRTFLFLFAVLFFLT---PAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCR 55


>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
          Length = 65

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 15/58 (25%), Positives = 26/58 (44%), Gaps = 3/58 (5%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCK 58
          MR   F+F VL  ++   P ++   +++C      C+  C  +E  I  C     CC+
Sbjct: 1  MRTFLFLFAVLFFLT---PAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCR 55


>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
          Length = 72

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 16/50 (32%), Positives = 21/50 (42%)

Query: 11 LSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          L L   +P R  F  +  C      CR KC + E+ I  C +   CC  K
Sbjct: 12 LLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61


>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
          Length = 72

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 16/50 (32%), Positives = 21/50 (42%)

Query: 11 LSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60
          L L   +P R  F  +  C      CR KC + E+ I  C +   CC  K
Sbjct: 12 LLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61


>gi|16905373 beta-defensin 118 [Homo sapiens]
          Length = 123

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 15/57 (26%), Positives = 25/57 (43%), Gaps = 2/57 (3%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICC 57
          M++L     +L L+  V P  ++    +C +   HCR +C   E     C +   CC
Sbjct: 1  MKLLLLALPMLVLLPQVIP--AYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACC 55


>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
          Length = 1541

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 10/35 (28%)

Query: 27  DECPSEYY--HCRLKCNADEHAITYCADFSICCKL 59
           D CP  YY  HCR KCN        CA+   C +L
Sbjct: 596 DGCPKGYYGKHCRKKCN--------CANRGRCHRL 622


>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
          Length = 156

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 1/57 (1%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICC 57
          M +L   F +  L++ V  + SF       +   HCR +C   E  I  C +   CC
Sbjct: 1  MNILMLTFIICGLLTRVT-KGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCC 56


>gi|195539372 ADAM metallopeptidase with thrombospondin type 1
           motif, 5 preproprotein [Homo sapiens]
          Length = 930

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 10/38 (26%), Positives = 20/38 (52%), Gaps = 5/38 (13%)

Query: 19  PRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSIC 56
           PR+  +  +E P + Y    +CN     +T+  ++S+C
Sbjct: 476 PRKQILGPEELPGQTYDATQQCN-----LTFGPEYSVC 508


>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
          Length = 88

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 10/23 (43%), Positives = 12/23 (52%)

Query: 35 HCRLKCNADEHAITYCADFSICC 57
          HCRL C   E +I  C +   CC
Sbjct: 28 HCRLLCKDGEDSIIRCRNRKRCC 50


>gi|74136827 beta-defensin 134 [Homo sapiens]
          Length = 66

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 18/59 (30%), Positives = 26/59 (44%), Gaps = 2/59 (3%)

Query: 1  MRVLFFVFGVLSLMSTVPPRRSFISNDECPSEYYH--CRLKCNADEHAITYCADFSICC 57
          M+ L  VF  L L   V    + +S++     Y +  CRL+C   E  + YC     CC
Sbjct: 1  MKPLLVVFVFLFLWDPVLAGINSLSSEMHKKCYKNGICRLECYESEMLVAYCMFQLECC 59


>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
          Length = 99

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 13/35 (37%), Positives = 17/35 (48%), Gaps = 1/35 (2%)

Query: 35 HCRLKCNADEHAITYCADFSICCKLKIIEIDGQKK 69
          HCR  C  +E     C +   CC L I E++  KK
Sbjct: 32 HCRKICRVNEVPEALCENGRYCC-LNIKELEACKK 65


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.142    0.479 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,831,961
Number of Sequences: 37866
Number of extensions: 99027
Number of successful extensions: 259
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 245
Number of HSP's gapped (non-prelim): 22
length of query: 70
length of database: 18,247,518
effective HSP length: 43
effective length of query: 27
effective length of database: 16,619,280
effective search space: 448720560
effective search space used: 448720560
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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