Search of human proteins with 11119430

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11119430 testis-specific kinase substrate [Homo sapiens]
         (592 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11119430 testis-specific kinase substrate [Homo sapiens]          1184   0.0  
gi|40538794 coiled-coil domain containing 21 [Homo sapiens]            53   9e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    52   2e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    52   2e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        52   2e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        52   2e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         52   2e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         52   2e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         52   2e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         52   2e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         52   2e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         52   2e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    50   6e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    50   6e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    50   6e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    49   1e-05
gi|81295809 pericentrin [Homo sapiens]                                 49   1e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             49   2e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    48   2e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    48   2e-05
gi|31543392 peroxisome proliferator-activated receptor gamma, co...    48   2e-05
gi|88196790 coiled-coil domain containing 88 [Homo sapiens]            48   2e-05
gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]             48   2e-05
gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]             48   2e-05
gi|226495417 coiled-coil domain containing 102A [Homo sapiens]         47   4e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    47   4e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    47   5e-05
gi|23503317 coiled-coil domain containing 96 [Homo sapiens]            47   5e-05
gi|122937219 F-box protein 41 [Homo sapiens]                           47   6e-05
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           46   8e-05

>gi|11119430 testis-specific kinase substrate [Homo sapiens]
          Length = 592

 Score = 1184 bits (3062), Expect = 0.0
 Identities = 592/592 (100%), Positives = 592/592 (100%)

Query: 1   MASVVVKTIWQSKEIHEAGDTPTGVESCSQLVPEAPRRVTSRAKGIPKKKKAVSFHGVEP 60
           MASVVVKTIWQSKEIHEAGDTPTGVESCSQLVPEAPRRVTSRAKGIPKKKKAVSFHGVEP
Sbjct: 1   MASVVVKTIWQSKEIHEAGDTPTGVESCSQLVPEAPRRVTSRAKGIPKKKKAVSFHGVEP 60

Query: 61  QMSHQPMHWCLNLKRSSACTNVSLLNLAAMEPTDSTGTDSTVEDLSGQLTLAGPPASPTL 120
           QMSHQPMHWCLNLKRSSACTNVSLLNLAAMEPTDSTGTDSTVEDLSGQLTLAGPPASPTL
Sbjct: 61  QMSHQPMHWCLNLKRSSACTNVSLLNLAAMEPTDSTGTDSTVEDLSGQLTLAGPPASPTL 120

Query: 121 PWDPDDADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQ 180
           PWDPDDADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQ
Sbjct: 121 PWDPDDADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQ 180

Query: 181 EAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQE 240
           EAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQE
Sbjct: 181 EAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQE 240

Query: 241 AELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVP 300
           AELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVP
Sbjct: 241 AELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVP 300

Query: 301 AGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGG 360
           AGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGG
Sbjct: 301 AGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGG 360

Query: 361 RVDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSAVSVASLRSELEGLGPLKPI 420
           RVDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSAVSVASLRSELEGLGPLKPI
Sbjct: 361 RVDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSAVSVASLRSELEGLGPLKPI 420

Query: 421 LEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVK 480
           LEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVK
Sbjct: 421 LEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVK 480

Query: 481 QRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLLTDKMKP 540
           QRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLLTDKMKP
Sbjct: 481 QRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLLTDKMKP 540

Query: 541 EEKMATLDHLHLKMCSLHDHLSNLPLEGSTGTMGGGSSAGTPPKQGGSAPEQ 592
           EEKMATLDHLHLKMCSLHDHLSNLPLEGSTGTMGGGSSAGTPPKQGGSAPEQ
Sbjct: 541 EEKMATLDHLHLKMCSLHDHLSNLPLEGSTGTMGGGSSAGTPPKQGGSAPEQ 592


>gi|40538794 coiled-coil domain containing 21 [Homo sapiens]
          Length = 762

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 67/303 (22%), Positives = 118/303 (38%), Gaps = 72/303 (23%)

Query: 126 DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEEL 185
           + ++  I   +   L +  + +   +E+    ++H+ +L+ +C   SE    ++Q  E L
Sbjct: 420 EVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETL 479

Query: 186 EGYCIQLK--ENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQ-----QQLQDETPRR 238
           E Y   L   E+  K ++ ++D+E+K+  L++    LE  L   Q     +++Q E+ R+
Sbjct: 480 ERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQ 539

Query: 239 QEAELQEPEEKQEPEEKQEPEEKQKPEAGL-SWNSLGPAATSQGCPGPPGSPDKPSRPHG 297
           +EAE        + ++  E    + PE  + SW                           
Sbjct: 540 REAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQK------------------------- 574

Query: 298 LVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGG 357
                     R      + E++ QK+    ++LR +V SL     QEEG  Q ALR    
Sbjct: 575 ----------RYDSLQKIVEKQQQKM----DQLRSQVQSLEQEVAQEEGTSQ-ALR---- 615

Query: 358 LGGRVDGFLGQWERAQREQAQTARDLQELRGRADELCT----MVERSAVSVASLRSELEG 413
                       E AQR  +     LQ+LR    EL      ++E++      LR    G
Sbjct: 616 ------------EEAQRRDSA----LQQLRTAVKELSVQNQDLIEKNLTLQEHLRQAQPG 659

Query: 414 LGP 416
             P
Sbjct: 660 SPP 662


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 95/441 (21%), Positives = 173/441 (39%), Gaps = 54/441 (12%)

Query: 136  VNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKEN 195
            + + L R  D I     + N   + ++ L+   S L E+L+  R    + E     L E 
Sbjct: 1092 LQAALARLDDEIA----QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE 1147

Query: 196  CWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEK--QEPE 253
               +   +ED    T   ++  A  E+++  L++ L +ET R  EA++QE  +K  Q  E
Sbjct: 1148 LEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RSHEAQVQEMRQKHAQAVE 1206

Query: 254  EKQEP-EEKQKPEAGLSWNSLGPAATSQGCPGP-----PGSPDKPSRPHGLVPAGWGMGP 307
            E  E  E+ ++ +A L  N       +    G          +   +   L      +  
Sbjct: 1207 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1266

Query: 308  RAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLG 367
            +  +G    E+   +L   + +L+ EV S+T   ++ EG   +  + +  L  ++     
Sbjct: 1267 KCSDG----ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1322

Query: 368  QWERAQREQAQTARDLQELRGRADELCTMVERSA--------------VSVASLRSELEG 413
              +   R++   +  L++L    + L   ++                 + ++  + +L+ 
Sbjct: 1323 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1382

Query: 414  LGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLSTESLQQLLDRALT 473
                   LEE  ++FQ          NL + ++   A  A    + +   LQQ LD    
Sbjct: 1383 FASTVEALEEGKKRFQKEIE------NLTQQYEEKAA--AYDKLEKTKNRLQQELD---D 1431

Query: 474  SLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHV----RAEA-------LSSTLRLA 522
             +VD   QR L       QR   ++L  E+   +K+     RAEA        + +L  A
Sbjct: 1432 LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARA 1491

Query: 523  QDEALRAK-NLLLTDKMKPEE 542
             +EAL AK  L  T+KM   E
Sbjct: 1492 LEEALEAKEELERTNKMLKAE 1512



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 97/472 (20%), Positives = 181/472 (38%), Gaps = 55/472 (11%)

Query: 133  LSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQL 192
            L+G    L +AK  +   K+K   +   VQ LQS+CS    + ER R E   L     +L
Sbjct: 1236 LAGELRVLGQAKQEVEHKKKK---LEAQVQELQSKCS----DGERARAE---LNDKVHKL 1285

Query: 193  KENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEA-----ELQEPE 247
            +     VT  + +AE K   L ++ A L  +L+  Q+ LQ+ET ++        +L+E  
Sbjct: 1286 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1345

Query: 248  EKQEPEEKQEPEEKQKPEAGLSWNSLGPA--------------ATSQGCPGPPGSPDKPS 293
               + +  +E E KQ  E  +S  ++  +              A  +G        +  +
Sbjct: 1346 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1405

Query: 294  RPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALR 353
            + +    A +    +  +     +QEL  L   ++  R+ VS+L  +  + +  + E   
Sbjct: 1406 QQYEEKAAAY---DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN 1462

Query: 354  LLG---------------------GLGGRVDGFLGQWERAQREQAQTARDLQELRGRADE 392
            +                        L   ++  L   E  +R       ++++L    D+
Sbjct: 1463 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1522

Query: 393  LCTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARC 452
            +   V     S  +L +++E +      LE+  +  ++++   +++M   +       + 
Sbjct: 1523 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1582

Query: 453  ASQGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRA 512
              + ++     LQ+ L    T L DE KQR L  A    ++L   + +LE QA +     
Sbjct: 1583 RDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--KKLEGDLKDLELQADSAIKGR 1640

Query: 513  EALSSTLRLAQDEALRAKNLLLTDKMKPEEKMATLDHLHLKMCSLHDHLSNL 564
            E     LR  Q +    +  L   +   +E  AT      K  SL   L  L
Sbjct: 1641 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1692



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 89/478 (18%), Positives = 186/478 (38%), Gaps = 56/478 (11%)

Query: 136  VNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKEN 195
            V++ L + ++   SL+++ +   +  Q+L+   S L+  L   +++ ++       L+E 
Sbjct: 1334 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG 1393

Query: 196  CWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQD-----ETPRRQEAELQEPEEKQ 250
              +  + +E+   +          LE+    LQQ+L D     +  R+  + L++ + K 
Sbjct: 1394 KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1453

Query: 251  EP---EEK----QEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGW 303
            +    EEK    +  +E+ + EA          + ++       + ++  R + ++ A  
Sbjct: 1454 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1513

Query: 304  G--MGPRAGEGPYVSEQELQK--LFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLG 359
               +  +   G  V E E  K  L T +EE++ ++  L       E A    LRL   + 
Sbjct: 1514 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDA---KLRLEVNM- 1569

Query: 360  GRVDGFLGQWER-AQREQAQTARDLQELRGRADELCTMVE---RSAVSVASLRSELEG-- 413
                   GQ+ER  Q    Q     ++L+ +  E  T +E   +     A+ + +LEG  
Sbjct: 1570 ---QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1626

Query: 414  --------------------LGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCA 453
                                L  L+  +++F R+ +++R   D      + ++       
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686

Query: 454  SQGSQL-----STESLQQLLDRALTSLVDEVKQR--GLTPACPSCQRLHKKILELERQAL 506
            +   QL     + E  ++  D     L +E+     G        +RL  +I +LE +  
Sbjct: 1687 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE 1746

Query: 507  AKHVRAEALSSTLRLAQDEALRAKNLLLTDKMKPEEKMATLDHLHLKMCSLHDHLSNL 564
             +    EA+S  +R A  +A +  N L T++   ++  +    L  +   L   L  +
Sbjct: 1747 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1804



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 92/470 (19%), Positives = 177/470 (37%), Gaps = 69/470 (14%)

Query: 129  ITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGY 188
            + E +S + + L   ++   +L   T   N+H +S+ SE  V  +  E+ RQE E+L+  
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNL---TKLKNKH-ESMISELEVRLKKEEKSRQELEKLKR- 1058

Query: 189  CIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEA------- 241
              +L+ +       + D + +   LK   A  EE+L+    +L DE  ++  A       
Sbjct: 1059 --KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL 1116

Query: 242  -----ELQE-------PEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGP---- 285
                 +LQE          K E +++   EE +  +  L  ++L   AT Q         
Sbjct: 1117 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE-DTLDSTATQQELRAKREQE 1175

Query: 286  ----PGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTAR- 340
                  + D+ +R H           +  E      Q +++L   +E+ +R  ++L    
Sbjct: 1176 VTVLKKALDEETRSH---------EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1226

Query: 341  --WHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELCTMVE 398
                +E   +   LR+LG     V+    + E   +E      D +  R   ++    ++
Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286

Query: 399  RSAVSVASLRSELEGLG-PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGS 457
                SV  + +E EG    L   +     Q Q+++   +L     R              
Sbjct: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ---ELLQEETR-------------Q 1330

Query: 458  QLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSS 517
            +L+  +  + L+    SL D++ +        + Q L + I  L  Q      + +  +S
Sbjct: 1331 KLNVSTKLRQLEEERNSLQDQLDEE-----MEAKQNLERHISTLNIQLSDSKKKLQDFAS 1385

Query: 518  TLRLAQDEALRAKNLLLTDKMKPEEKMATLDHLHLKMCSLHDHLSNLPLE 567
            T+   ++   R +  +     + EEK A  D L      L   L +L ++
Sbjct: 1386 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 34/169 (20%), Positives = 68/169 (40%), Gaps = 24/169 (14%)

Query: 123  DPDDADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEA 182
            D +  ++ E L+   SG    +D    L+ +  ++ + ++  Q     +S+ + +  Q+A
Sbjct: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766

Query: 183  EELEGYCIQLKENCWKVTRSVEDAEIKTNVL---------------KQNSALLEEKLRYL 227
            E+L       +    K   + +  E +   L               K   A LE K+  L
Sbjct: 1767 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1826

Query: 228  QQQLQDETPRRQEA---------ELQEPEEKQEPEEKQEPEEKQKPEAG 267
            ++Q++ E   +Q A         +L+E   + E E K   + K++ E G
Sbjct: 1827 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1875



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 87/413 (21%), Positives = 158/413 (38%), Gaps = 43/413 (10%)

Query: 144  KDSITSLKEKTNRVNQHVQSLQSECSVLSEN---LERRRQEAEELEGYCIQLKENCWKVT 200
            +D +   KE+  +    ++ L+ + S L+E    L+ + Q   EL     +++     V 
Sbjct: 858  EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR-----VR 912

Query: 201  RSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEE 260
             + +  E++  + +  + L EE+ R  Q Q + +   +Q  +L+E  E++E   ++   E
Sbjct: 913  LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE 972

Query: 261  KQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQEL 320
            K   EA +    L              S ++      +      +           E+E 
Sbjct: 973  KVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL---------AEEEEK 1021

Query: 321  QKLFTGIEELRRE-VSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQT 379
             K  T ++      +S L  R  +EE + QE  +L   L G    F    E+    QAQ 
Sbjct: 1022 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF---HEQIADLQAQI 1078

Query: 380  ARDLQELRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSM 439
            A    +L  + +EL   + R    +A   + L+ +  L+  + +      + R   + + 
Sbjct: 1079 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1138

Query: 440  NLDRSHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG----LTPACPSCQRLH 495
               R           +   L TE L+  LD   T      K+      L  A     R H
Sbjct: 1139 KQKRD-------LGEELEALKTE-LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1190

Query: 496  KKILELERQALAKHVRA-EALSSTLRLAQDEALRAKNLLLTDKMKPEEKMATL 547
            +  ++  RQ   KH +A E L+  L    ++  RAK  L  +K   E++ A L
Sbjct: 1191 EAQVQEMRQ---KHAQAVEELTEQL----EQFKRAKANLDKNKQTLEKENADL 1236



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 10/84 (11%)

Query: 175 LERRRQEAEELEGYCIQLKENCWKVTRSVED-AEIKTNVLKQNSALLEEKLRYLQQQLQD 233
           L+  RQE E      +Q KE+  + T+  +  AE +   L+Q  + L E+   LQ+QLQ 
Sbjct: 845 LQVTRQEEE------MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA 898

Query: 234 ETPRRQEAE---LQEPEEKQEPEE 254
           ET    EAE   ++   +KQE EE
Sbjct: 899 ETELYAEAEEMRVRLAAKKQELEE 922


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 95/441 (21%), Positives = 173/441 (39%), Gaps = 54/441 (12%)

Query: 136  VNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKEN 195
            + + L R  D I     + N   + ++ L+   S L E+L+  R    + E     L E 
Sbjct: 1099 LQAALARLDDEIA----QKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEE 1154

Query: 196  CWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEK--QEPE 253
               +   +ED    T   ++  A  E+++  L++ L +ET R  EA++QE  +K  Q  E
Sbjct: 1155 LEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEET-RSHEAQVQEMRQKHAQAVE 1213

Query: 254  EKQEP-EEKQKPEAGLSWNSLGPAATSQGCPGP-----PGSPDKPSRPHGLVPAGWGMGP 307
            E  E  E+ ++ +A L  N       +    G          +   +   L      +  
Sbjct: 1214 ELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQS 1273

Query: 308  RAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLG 367
            +  +G    E+   +L   + +L+ EV S+T   ++ EG   +  + +  L  ++     
Sbjct: 1274 KCSDG----ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQE 1329

Query: 368  QWERAQREQAQTARDLQELRGRADELCTMVERSA--------------VSVASLRSELEG 413
              +   R++   +  L++L    + L   ++                 + ++  + +L+ 
Sbjct: 1330 LLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQD 1389

Query: 414  LGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLSTESLQQLLDRALT 473
                   LEE  ++FQ          NL + ++   A  A    + +   LQQ LD    
Sbjct: 1390 FASTVEALEEGKKRFQKEIE------NLTQQYEEKAA--AYDKLEKTKNRLQQELD---D 1438

Query: 474  SLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHV----RAEA-------LSSTLRLA 522
             +VD   QR L       QR   ++L  E+   +K+     RAEA        + +L  A
Sbjct: 1439 LVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARA 1498

Query: 523  QDEALRAK-NLLLTDKMKPEE 542
             +EAL AK  L  T+KM   E
Sbjct: 1499 LEEALEAKEELERTNKMLKAE 1519



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 97/472 (20%), Positives = 181/472 (38%), Gaps = 55/472 (11%)

Query: 133  LSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQL 192
            L+G    L +AK  +   K+K   +   VQ LQS+CS    + ER R E   L     +L
Sbjct: 1243 LAGELRVLGQAKQEVEHKKKK---LEAQVQELQSKCS----DGERARAE---LNDKVHKL 1292

Query: 193  KENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEA-----ELQEPE 247
            +     VT  + +AE K   L ++ A L  +L+  Q+ LQ+ET ++        +L+E  
Sbjct: 1293 QNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEER 1352

Query: 248  EKQEPEEKQEPEEKQKPEAGLSWNSLGPA--------------ATSQGCPGPPGSPDKPS 293
               + +  +E E KQ  E  +S  ++  +              A  +G        +  +
Sbjct: 1353 NSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLT 1412

Query: 294  RPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALR 353
            + +    A +    +  +     +QEL  L   ++  R+ VS+L  +  + +  + E   
Sbjct: 1413 QQYEEKAAAY---DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKN 1469

Query: 354  LLG---------------------GLGGRVDGFLGQWERAQREQAQTARDLQELRGRADE 392
            +                        L   ++  L   E  +R       ++++L    D+
Sbjct: 1470 ISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDD 1529

Query: 393  LCTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARC 452
            +   V     S  +L +++E +      LE+  +  ++++   +++M   +       + 
Sbjct: 1530 VGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQA 1589

Query: 453  ASQGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRA 512
              + ++     LQ+ L    T L DE KQR L  A    ++L   + +LE QA +     
Sbjct: 1590 RDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK--KKLEGDLKDLELQADSAIKGR 1647

Query: 513  EALSSTLRLAQDEALRAKNLLLTDKMKPEEKMATLDHLHLKMCSLHDHLSNL 564
            E     LR  Q +    +  L   +   +E  AT      K  SL   L  L
Sbjct: 1648 EEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQL 1699



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 89/478 (18%), Positives = 186/478 (38%), Gaps = 56/478 (11%)

Query: 136  VNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKEN 195
            V++ L + ++   SL+++ +   +  Q+L+   S L+  L   +++ ++       L+E 
Sbjct: 1341 VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEG 1400

Query: 196  CWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQD-----ETPRRQEAELQEPEEKQ 250
              +  + +E+   +          LE+    LQQ+L D     +  R+  + L++ + K 
Sbjct: 1401 KKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKF 1460

Query: 251  EP---EEK----QEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGW 303
            +    EEK    +  +E+ + EA          + ++       + ++  R + ++ A  
Sbjct: 1461 DQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEM 1520

Query: 304  G--MGPRAGEGPYVSEQELQK--LFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLG 359
               +  +   G  V E E  K  L T +EE++ ++  L       E A    LRL   + 
Sbjct: 1521 EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDA---KLRLEVNM- 1576

Query: 360  GRVDGFLGQWER-AQREQAQTARDLQELRGRADELCTMVE---RSAVSVASLRSELEG-- 413
                   GQ+ER  Q    Q     ++L+ +  E  T +E   +     A+ + +LEG  
Sbjct: 1577 ---QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1633

Query: 414  --------------------LGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCA 453
                                L  L+  +++F R+ +++R   D      + ++       
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693

Query: 454  SQGSQL-----STESLQQLLDRALTSLVDEVKQR--GLTPACPSCQRLHKKILELERQAL 506
            +   QL     + E  ++  D     L +E+     G        +RL  +I +LE +  
Sbjct: 1694 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE 1753

Query: 507  AKHVRAEALSSTLRLAQDEALRAKNLLLTDKMKPEEKMATLDHLHLKMCSLHDHLSNL 564
             +    EA+S  +R A  +A +  N L T++   ++  +    L  +   L   L  +
Sbjct: 1754 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEM 1811



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 92/470 (19%), Positives = 177/470 (37%), Gaps = 69/470 (14%)

Query: 129  ITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGY 188
            + E +S + + L   ++   +L   T   N+H +S+ SE  V  +  E+ RQE E+L+  
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNL---TKLKNKH-ESMISELEVRLKKEEKSRQELEKLKR- 1065

Query: 189  CIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEA------- 241
              +L+ +       + D + +   LK   A  EE+L+    +L DE  ++  A       
Sbjct: 1066 --KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIREL 1123

Query: 242  -----ELQE-------PEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGP---- 285
                 +LQE          K E +++   EE +  +  L  ++L   AT Q         
Sbjct: 1124 EGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELE-DTLDSTATQQELRAKREQE 1182

Query: 286  ----PGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTAR- 340
                  + D+ +R H           +  E      Q +++L   +E+ +R  ++L    
Sbjct: 1183 VTVLKKALDEETRSH---------EAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK 1233

Query: 341  --WHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELCTMVE 398
                +E   +   LR+LG     V+    + E   +E      D +  R   ++    ++
Sbjct: 1234 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1293

Query: 399  RSAVSVASLRSELEGLG-PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGS 457
                SV  + +E EG    L   +     Q Q+++   +L     R              
Sbjct: 1294 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQ---ELLQEETR-------------Q 1337

Query: 458  QLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSS 517
            +L+  +  + L+    SL D++ +        + Q L + I  L  Q      + +  +S
Sbjct: 1338 KLNVSTKLRQLEEERNSLQDQLDEE-----MEAKQNLERHISTLNIQLSDSKKKLQDFAS 1392

Query: 518  TLRLAQDEALRAKNLLLTDKMKPEEKMATLDHLHLKMCSLHDHLSNLPLE 567
            T+   ++   R +  +     + EEK A  D L      L   L +L ++
Sbjct: 1393 TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 34/169 (20%), Positives = 68/169 (40%), Gaps = 24/169 (14%)

Query: 123  DPDDADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEA 182
            D +  ++ E L+   SG    +D    L+ +  ++ + ++  Q     +S+ + +  Q+A
Sbjct: 1714 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773

Query: 183  EELEGYCIQLKENCWKVTRSVEDAEIKTNVL---------------KQNSALLEEKLRYL 227
            E+L       +    K   + +  E +   L               K   A LE K+  L
Sbjct: 1774 EQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQL 1833

Query: 228  QQQLQDETPRRQEA---------ELQEPEEKQEPEEKQEPEEKQKPEAG 267
            ++Q++ E   +Q A         +L+E   + E E K   + K++ E G
Sbjct: 1834 EEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKG 1882



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 87/413 (21%), Positives = 158/413 (38%), Gaps = 43/413 (10%)

Query: 144  KDSITSLKEKTNRVNQHVQSLQSECSVLSEN---LERRRQEAEELEGYCIQLKENCWKVT 200
            +D +   KE+  +    ++ L+ + S L+E    L+ + Q   EL     +++     V 
Sbjct: 865  EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR-----VR 919

Query: 201  RSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEE 260
             + +  E++  + +  + L EE+ R  Q Q + +   +Q  +L+E  E++E   ++   E
Sbjct: 920  LAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE 979

Query: 261  KQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQEL 320
            K   EA +    L              S ++      +      +           E+E 
Sbjct: 980  KVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNL---------AEEEEK 1028

Query: 321  QKLFTGIEELRRE-VSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQT 379
             K  T ++      +S L  R  +EE + QE  +L   L G    F    E+    QAQ 
Sbjct: 1029 AKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF---HEQIADLQAQI 1085

Query: 380  ARDLQELRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSM 439
            A    +L  + +EL   + R    +A   + L+ +  L+  + +      + R   + + 
Sbjct: 1086 AELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAE 1145

Query: 440  NLDRSHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG----LTPACPSCQRLH 495
               R           +   L TE L+  LD   T      K+      L  A     R H
Sbjct: 1146 KQKRD-------LGEELEALKTE-LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSH 1197

Query: 496  KKILELERQALAKHVRA-EALSSTLRLAQDEALRAKNLLLTDKMKPEEKMATL 547
            +  ++  RQ   KH +A E L+  L    ++  RAK  L  +K   E++ A L
Sbjct: 1198 EAQVQEMRQ---KHAQAVEELTEQL----EQFKRAKANLDKNKQTLEKENADL 1243



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 10/84 (11%)

Query: 175 LERRRQEAEELEGYCIQLKENCWKVTRSVED-AEIKTNVLKQNSALLEEKLRYLQQQLQD 233
           L+  RQE E      +Q KE+  + T+  +  AE +   L+Q  + L E+   LQ+QLQ 
Sbjct: 852 LQVTRQEEE------MQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQA 905

Query: 234 ETPRRQEAE---LQEPEEKQEPEE 254
           ET    EAE   ++   +KQE EE
Sbjct: 906 ETELYAEAEEMRVRLAAKKQELEE 929


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 93/418 (22%), Positives = 164/418 (39%), Gaps = 73/418 (17%)

Query: 131  EILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCI 190
            ++ SG  S +    D  T   E T   +Q+++        +SE L R  +E    E    
Sbjct: 1304 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIK-------FISETLRRMEEEERLAEQQRA 1356

Query: 191  QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQ 250
            + +E   +V  ++E          Q  A  E + + LQQ++Q+E  RR+EA +   ++K+
Sbjct: 1357 EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKR 1416

Query: 251  EPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAG 310
              +E+ + + +Q  EA +   +                                   R  
Sbjct: 1417 SIQEELQ-QLRQSSEAEIQAKA-----------------------------------RQA 1440

Query: 311  EGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWE 370
            E    S   ++      EE+R     L A   Q  GA  E    L  L  R +    Q  
Sbjct: 1441 EAAERSRLRIE------EEIRVVRLQLEATERQRGGAEGE----LQALRARAEEAEAQKR 1490

Query: 371  RAQREQAQTARDLQE----LRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGR 426
            +AQ E  +  R +Q+     R    EL + V+  A +    +  L+ L  L+   EE  R
Sbjct: 1491 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1550

Query: 427  QFQNS--RRGPDLSMNLDRSHQGNCARCASQGSQLS--TESLQQLLDR---ALTSLVDEV 479
            + + +   R   + + L+ + +   A   S+ +  +  T  L++ L     A+  L +E 
Sbjct: 1551 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610

Query: 480  KQRGLTPACPSCQRLHKKI-LELER------QALAKHVRAEALSSTLRLAQDEALRAK 530
            ++R    A    +R  ++   ELER      +AL   ++AE ++    LAQ EA + K
Sbjct: 1611 ERRAQQQA--EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAE- 207
            ++++K   + Q +Q  QS    L    E  R+ AEE E   +Q +    +  R VE+AE 
Sbjct: 2057 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2116

Query: 208  IKTNVLKQNSALLEEK--LRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            +K +  +Q  A  + +     L+++ + E  RR +AE     +KQ  + + E  +K
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 92/423 (21%), Positives = 162/423 (38%), Gaps = 64/423 (15%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            ADI E L+ +        +    L E T R  + V+    E   L  + E+      ELE
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEE---EILALKASFEKAAAGKAELE 1945

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ------DETPRRQE 240
                +++ N     RS E AE++    +Q +A  E + R  ++++Q      +E  R+++
Sbjct: 1946 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 2005

Query: 241  AELQEPEE-KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLV 299
            A L+E E  K + EE +   E+ + E+         AA  +             + H   
Sbjct: 2006 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR--------LQAEEKAHAFA 2057

Query: 300  PAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV-SSLTARWHQEEGAVQEALRLLGGL 358
                       +     +Q LQ+  + +++LR E  ++  A    EE  VQ         
Sbjct: 2058 ---------VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ--------- 2099

Query: 359  GGRVDGFLGQWERAQREQAQTARDLQE---LRGRADELCTMVERSAVSVASLRSELEGLG 415
                         A+RE AQ+ R ++E   L+  A+E      ++  +   LR E E   
Sbjct: 2100 -------------AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2146

Query: 416  PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQ-LSTESLQQLLDRALTS 474
              +   E+   +    ++  D  M   +       R  +Q  Q L+T  LQ        +
Sbjct: 2147 ARRAQAEQAALR---QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2203

Query: 475  LVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLL 534
            L+DE  QR    A  + ++      ++E +  +  V+ E LS      + E    + L+L
Sbjct: 2204 LLDEELQRLKAEATEAARQRS----QVEEELFSVRVQMEELSKLKARIEAE---NRALIL 2256

Query: 535  TDK 537
             DK
Sbjct: 2257 RDK 2259



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 92/412 (22%), Positives = 144/412 (34%), Gaps = 110/412 (26%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            S  EKT ++ + +Q      + L E  ERR Q+  E E              R   + E+
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER------------AREEAEREL 1631

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            +   LK N A        L+ +LQ E   +Q++  Q   EKQ+ E ++E   + K E   
Sbjct: 1632 ERWQLKANEA--------LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE--- 1680

Query: 269  SWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIE 328
                                                   +A     ++EQEL+K      
Sbjct: 1681 --------------------------------------EQAVRQRELAEQELEK------ 1696

Query: 329  ELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRG 388
              +R+++  TA+  Q   A QE +RL                RA+ EQ +  R L E   
Sbjct: 1697 --QRQLAEGTAQ--QRLAAEQELIRL----------------RAETEQGEQQRQLLE--- 1733

Query: 389  RADELCTMVERSAVSVASLRSELEG-----LGPLKPILEEFGRQFQNSRRGPDLSMNLDR 443
               E    ++R A +    R ELE         ++ +L    R  + SR   + S     
Sbjct: 1734 ---EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1790

Query: 444  SHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG-----LTPACPSCQRLHKKI 498
            +  G     A + ++L   + +    R L    D  +QR      L     +     +  
Sbjct: 1791 AEAGRFRELAEEAARLRALAEEAKRQRQLAE-EDAARQRAEAERVLAEKLAAIGEATRLK 1849

Query: 499  LELERQALAKHVRAEALSSTLRLAQDEALRAKNL---LLTDKMKPEEKMATL 547
             E E     K    E L    RLA+DEA + + L       K   EE++A L
Sbjct: 1850 TEAEIALKEKEAENERLR---RLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1898



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 43/193 (22%), Positives = 86/193 (44%), Gaps = 18/193 (9%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            SL ++   + Q    L+    +  + + + +Q  EE +    Q+++   ++  S+E+A  
Sbjct: 2501 SLLQRERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2557

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            + +  ++     +E+L+ L+QQ      RRQ+ EL   E ++  E+ Q  EE+ +     
Sbjct: 2558 RQHEAEEGVRRKQEELQQLEQQ------RRQQEELLAEENQRLREQLQLLEEQHRAALAH 2611

Query: 269  SWN-SLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGM-----GPRAGEGPYVSEQELQK 322
            S   +    A ++  P    + D P+       +  G+       R  E   +S +ELQ+
Sbjct: 2612 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2671

Query: 323  LFTG---IEELRR 332
            L  G   ++EL R
Sbjct: 2672 LAQGHTTVDELAR 2684



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 67/295 (22%), Positives = 111/295 (37%), Gaps = 48/295 (16%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            A+  E L+ V + L + +    +  +   +  +  + LQ     + E + RR + A + +
Sbjct: 1356 AEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVDAQ 1412

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQDETPRRQEA 241
                 ++E   ++ +S E AEI+    +  +A      +EE++R ++ QL+    +R  A
Sbjct: 1413 QQKRSIQEELQQLRQSSE-AEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1471

Query: 242  ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPA 301
            E     E Q    + E  E QK +A      L      +         +  SR      A
Sbjct: 1472 E----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1527

Query: 302  GWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGR 361
                            +E Q+    +EELR +      R  Q E  V+ A ++   L   
Sbjct: 1528 A---------------REKQRALQALEELRLQAEEAERRLRQAE--VERARQVQVAL--- 1567

Query: 362  VDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSA----VSVASLRSELE 412
                    E AQR       +LQ  R    E    +ERS     V+VA LR E E
Sbjct: 1568 --------ETAQR---SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1611



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 47/201 (23%)

Query: 156  RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI-KTNVLK 214
            R+ + +  L+ E   L +  +  + ++EE++   +Q +E   + T++++ + + + + L 
Sbjct: 2447 RLREAIAELEREKEKLQQEAKLLQLKSEEMQ--TVQ-QEQLLQETQALQQSFLSEKDSLL 2503

Query: 215  QNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLG 274
            Q    +E++   L+Q  QDE      A+ Q+  E+Q+ +++Q  +E+Q+  A +      
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEV-----AKAQQLREEQQRQQQQMEQERQRLVASME----- 2553

Query: 275  PAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV 334
                           +   R H            A EG    ++ELQ+L    E+ RR+ 
Sbjct: 2554 ---------------EARRRQH-----------EAEEGVRRKQEELQQL----EQQRRQQ 2583

Query: 335  SSLTARWHQEEGAVQEALRLL 355
              L A   +E   ++E L+LL
Sbjct: 2584 EELLA---EENQRLREQLQLL 2601



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 159  QHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA 218
            Q  Q L  E       LE  RQ   E+     +LK    +++R+   AE      ++ + 
Sbjct: 2352 QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAE 2411

Query: 219  LLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPE-------EKQEPEEKQKPEAGL 268
             + EKL   +   Q++    Q  E+Q  +   + E       E +  +EK + EA L
Sbjct: 2412 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2468



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 86/449 (19%), Positives = 167/449 (37%), Gaps = 89/449 (19%)

Query: 126  DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQ--SECSVLS-----ENLERR 178
            + +  E+   +   +VR +++    +++   + + +Q L+  SE  + +     E  ER 
Sbjct: 1387 EREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERS 1446

Query: 179  RQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQD 233
            R   EE E   ++L+    +  R   + E++    +   A       +E+   L++Q+QD
Sbjct: 1447 RLRIEE-EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505

Query: 234  ETPRRQEAELQ-------EPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPP 286
            E+ R+++AE++       E E  +E +   +  E+ + +A  +   L  A   +      
Sbjct: 1506 ESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA----- 1560

Query: 287  GSPDKPSRPHGLVPAGWGMGPRAGEGPYVS------------EQELQKLFTGIEELRREV 334
                        V        R+ E    S            E+ LQ+    + +LR E 
Sbjct: 1561 ----------RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610

Query: 335  SSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELC 394
                 +  + E A +EA R L              ER Q +    A +   LR +A+E+ 
Sbjct: 1611 ERRAQQQAEAERAREEAEREL--------------ERWQLK----ANEALRLRLQAEEVA 1652

Query: 395  TMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCAS 454
                 +       + E E     +   EE     Q  R+       L++  Q       +
Sbjct: 1653 QQKSLAQAEAEKQKEEAEREARRRGKAEE-----QAVRQRELAEQELEKQRQ------LA 1701

Query: 455  QGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEA 514
            +G+     + +Q L R         +QR         Q L +++  L+R+A A   + + 
Sbjct: 1702 EGTAQQRLAAEQELIRLRAETEQGEQQR---------QLLEEELARLQREAAAATQKRQE 1752

Query: 515  LSSTLRLAQDEALRAKNLLLTDKMKPEEK 543
            L + L   + E      +LL  K + EE+
Sbjct: 1753 LEAELAKVRAE----MEVLLASKARAEEE 1777



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            ++R KD+     ++     + V    +  SV ++   R RQ AEE       L E   K 
Sbjct: 2255 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2314

Query: 200  T-RSVEDA---EIKTNVLKQNSALLEEKLRYLQ-------QQLQDET---PRRQEAELQE 245
              ++V++A   + +  +L+Q   L +E+ R LQ       QQL +ET    R  EAE Q 
Sbjct: 2315 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2374

Query: 246  PEEKQEPEEK 255
              E     E+
Sbjct: 2375 QLEMSAEAER 2384


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 93/418 (22%), Positives = 164/418 (39%), Gaps = 73/418 (17%)

Query: 131  EILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCI 190
            ++ SG  S +    D  T   E T   +Q+++        +SE L R  +E    E    
Sbjct: 1308 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIK-------FISETLRRMEEEERLAEQQRA 1360

Query: 191  QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQ 250
            + +E   +V  ++E          Q  A  E + + LQQ++Q+E  RR+EA +   ++K+
Sbjct: 1361 EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKR 1420

Query: 251  EPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAG 310
              +E+ + + +Q  EA +   +                                   R  
Sbjct: 1421 SIQEELQ-QLRQSSEAEIQAKA-----------------------------------RQA 1444

Query: 311  EGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWE 370
            E    S   ++      EE+R     L A   Q  GA  E    L  L  R +    Q  
Sbjct: 1445 EAAERSRLRIE------EEIRVVRLQLEATERQRGGAEGE----LQALRARAEEAEAQKR 1494

Query: 371  RAQREQAQTARDLQE----LRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGR 426
            +AQ E  +  R +Q+     R    EL + V+  A +    +  L+ L  L+   EE  R
Sbjct: 1495 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1554

Query: 427  QFQNS--RRGPDLSMNLDRSHQGNCARCASQGSQLS--TESLQQLLDR---ALTSLVDEV 479
            + + +   R   + + L+ + +   A   S+ +  +  T  L++ L     A+  L +E 
Sbjct: 1555 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1614

Query: 480  KQRGLTPACPSCQRLHKKI-LELER------QALAKHVRAEALSSTLRLAQDEALRAK 530
            ++R    A    +R  ++   ELER      +AL   ++AE ++    LAQ EA + K
Sbjct: 1615 ERRAQQQA--EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1670



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAE- 207
            ++++K   + Q +Q  QS    L    E  R+ AEE E   +Q +    +  R VE+AE 
Sbjct: 2061 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2120

Query: 208  IKTNVLKQNSALLEEK--LRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            +K +  +Q  A  + +     L+++ + E  RR +AE     +KQ  + + E  +K
Sbjct: 2121 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2176



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 92/423 (21%), Positives = 162/423 (38%), Gaps = 64/423 (15%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            ADI E L+ +        +    L E T R  + V+    E   L  + E+      ELE
Sbjct: 1893 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEE---EILALKASFEKAAAGKAELE 1949

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ------DETPRRQE 240
                +++ N     RS E AE++    +Q +A  E + R  ++++Q      +E  R+++
Sbjct: 1950 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 2009

Query: 241  AELQEPEE-KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLV 299
            A L+E E  K + EE +   E+ + E+         AA  +             + H   
Sbjct: 2010 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR--------LQAEEKAHAFA 2061

Query: 300  PAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV-SSLTARWHQEEGAVQEALRLLGGL 358
                       +     +Q LQ+  + +++LR E  ++  A    EE  VQ         
Sbjct: 2062 ---------VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ--------- 2103

Query: 359  GGRVDGFLGQWERAQREQAQTARDLQE---LRGRADELCTMVERSAVSVASLRSELEGLG 415
                         A+RE AQ+ R ++E   L+  A+E      ++  +   LR E E   
Sbjct: 2104 -------------AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2150

Query: 416  PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQ-LSTESLQQLLDRALTS 474
              +   E+   +    ++  D  M   +       R  +Q  Q L+T  LQ        +
Sbjct: 2151 ARRAQAEQAALR---QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2207

Query: 475  LVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLL 534
            L+DE  QR    A  + ++      ++E +  +  V+ E LS      + E    + L+L
Sbjct: 2208 LLDEELQRLKAEATEAARQRS----QVEEELFSVRVQMEELSKLKARIEAE---NRALIL 2260

Query: 535  TDK 537
             DK
Sbjct: 2261 RDK 2263



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 92/412 (22%), Positives = 144/412 (34%), Gaps = 110/412 (26%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            S  EKT ++ + +Q      + L E  ERR Q+  E E              R   + E+
Sbjct: 1588 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER------------AREEAEREL 1635

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            +   LK N A        L+ +LQ E   +Q++  Q   EKQ+ E ++E   + K E   
Sbjct: 1636 ERWQLKANEA--------LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE--- 1684

Query: 269  SWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIE 328
                                                   +A     ++EQEL+K      
Sbjct: 1685 --------------------------------------EQAVRQRELAEQELEK------ 1700

Query: 329  ELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRG 388
              +R+++  TA+  Q   A QE +RL                RA+ EQ +  R L E   
Sbjct: 1701 --QRQLAEGTAQ--QRLAAEQELIRL----------------RAETEQGEQQRQLLE--- 1737

Query: 389  RADELCTMVERSAVSVASLRSELEG-----LGPLKPILEEFGRQFQNSRRGPDLSMNLDR 443
               E    ++R A +    R ELE         ++ +L    R  + SR   + S     
Sbjct: 1738 ---EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1794

Query: 444  SHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG-----LTPACPSCQRLHKKI 498
            +  G     A + ++L   + +    R L    D  +QR      L     +     +  
Sbjct: 1795 AEAGRFRELAEEAARLRALAEEAKRQRQLAE-EDAARQRAEAERVLAEKLAAIGEATRLK 1853

Query: 499  LELERQALAKHVRAEALSSTLRLAQDEALRAKNL---LLTDKMKPEEKMATL 547
             E E     K    E L    RLA+DEA + + L       K   EE++A L
Sbjct: 1854 TEAEIALKEKEAENERLR---RLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1902



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 43/193 (22%), Positives = 86/193 (44%), Gaps = 18/193 (9%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            SL ++   + Q    L+    +  + + + +Q  EE +    Q+++   ++  S+E+A  
Sbjct: 2505 SLLQRERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2561

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            + +  ++     +E+L+ L+QQ      RRQ+ EL   E ++  E+ Q  EE+ +     
Sbjct: 2562 RQHEAEEGVRRKQEELQQLEQQ------RRQQEELLAEENQRLREQLQLLEEQHRAALAH 2615

Query: 269  SWN-SLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGM-----GPRAGEGPYVSEQELQK 322
            S   +    A ++  P    + D P+       +  G+       R  E   +S +ELQ+
Sbjct: 2616 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2675

Query: 323  LFTG---IEELRR 332
            L  G   ++EL R
Sbjct: 2676 LAQGHTTVDELAR 2688



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 67/295 (22%), Positives = 111/295 (37%), Gaps = 48/295 (16%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            A+  E L+ V + L + +    +  +   +  +  + LQ     + E + RR + A + +
Sbjct: 1360 AEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVDAQ 1416

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQDETPRRQEA 241
                 ++E   ++ +S E AEI+    +  +A      +EE++R ++ QL+    +R  A
Sbjct: 1417 QQKRSIQEELQQLRQSSE-AEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1475

Query: 242  ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPA 301
            E     E Q    + E  E QK +A      L      +         +  SR      A
Sbjct: 1476 E----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1531

Query: 302  GWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGR 361
                            +E Q+    +EELR +      R  Q E  V+ A ++   L   
Sbjct: 1532 A---------------REKQRALQALEELRLQAEEAERRLRQAE--VERARQVQVAL--- 1571

Query: 362  VDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSA----VSVASLRSELE 412
                    E AQR       +LQ  R    E    +ERS     V+VA LR E E
Sbjct: 1572 --------ETAQR---SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1615



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 47/201 (23%)

Query: 156  RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI-KTNVLK 214
            R+ + +  L+ E   L +  +  + ++EE++   +Q +E   + T++++ + + + + L 
Sbjct: 2451 RLREAIAELEREKEKLQQEAKLLQLKSEEMQ--TVQ-QEQLLQETQALQQSFLSEKDSLL 2507

Query: 215  QNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLG 274
            Q    +E++   L+Q  QDE      A+ Q+  E+Q+ +++Q  +E+Q+  A +      
Sbjct: 2508 QRERFIEQEKAKLEQLFQDEV-----AKAQQLREEQQRQQQQMEQERQRLVASME----- 2557

Query: 275  PAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV 334
                           +   R H            A EG    ++ELQ+L    E+ RR+ 
Sbjct: 2558 ---------------EARRRQH-----------EAEEGVRRKQEELQQL----EQQRRQQ 2587

Query: 335  SSLTARWHQEEGAVQEALRLL 355
              L A   +E   ++E L+LL
Sbjct: 2588 EELLA---EENQRLREQLQLL 2605



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 159  QHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA 218
            Q  Q L  E       LE  RQ   E+     +LK    +++R+   AE      ++ + 
Sbjct: 2356 QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAE 2415

Query: 219  LLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPE-------EKQEPEEKQKPEAGL 268
             + EKL   +   Q++    Q  E+Q  +   + E       E +  +EK + EA L
Sbjct: 2416 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2472



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 86/449 (19%), Positives = 167/449 (37%), Gaps = 89/449 (19%)

Query: 126  DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQ--SECSVLS-----ENLERR 178
            + +  E+   +   +VR +++    +++   + + +Q L+  SE  + +     E  ER 
Sbjct: 1391 EREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERS 1450

Query: 179  RQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQD 233
            R   EE E   ++L+    +  R   + E++    +   A       +E+   L++Q+QD
Sbjct: 1451 RLRIEE-EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1509

Query: 234  ETPRRQEAELQ-------EPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPP 286
            E+ R+++AE++       E E  +E +   +  E+ + +A  +   L  A   +      
Sbjct: 1510 ESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA----- 1564

Query: 287  GSPDKPSRPHGLVPAGWGMGPRAGEGPYVS------------EQELQKLFTGIEELRREV 334
                        V        R+ E    S            E+ LQ+    + +LR E 
Sbjct: 1565 ----------RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1614

Query: 335  SSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELC 394
                 +  + E A +EA R L              ER Q +    A +   LR +A+E+ 
Sbjct: 1615 ERRAQQQAEAERAREEAEREL--------------ERWQLK----ANEALRLRLQAEEVA 1656

Query: 395  TMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCAS 454
                 +       + E E     +   EE     Q  R+       L++  Q       +
Sbjct: 1657 QQKSLAQAEAEKQKEEAEREARRRGKAEE-----QAVRQRELAEQELEKQRQ------LA 1705

Query: 455  QGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEA 514
            +G+     + +Q L R         +QR         Q L +++  L+R+A A   + + 
Sbjct: 1706 EGTAQQRLAAEQELIRLRAETEQGEQQR---------QLLEEELARLQREAAAATQKRQE 1756

Query: 515  LSSTLRLAQDEALRAKNLLLTDKMKPEEK 543
            L + L   + E      +LL  K + EE+
Sbjct: 1757 LEAELAKVRAE----MEVLLASKARAEEE 1781



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            ++R KD+     ++     + V    +  SV ++   R RQ AEE       L E   K 
Sbjct: 2259 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2318

Query: 200  T-RSVEDA---EIKTNVLKQNSALLEEKLRYLQ-------QQLQDET---PRRQEAELQE 245
              ++V++A   + +  +L+Q   L +E+ R LQ       QQL +ET    R  EAE Q 
Sbjct: 2319 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2378

Query: 246  PEEKQEPEEK 255
              E     E+
Sbjct: 2379 QLEMSAEAER 2388


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 93/418 (22%), Positives = 164/418 (39%), Gaps = 73/418 (17%)

Query: 131  EILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCI 190
            ++ SG  S +    D  T   E T   +Q+++        +SE L R  +E    E    
Sbjct: 1304 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIK-------FISETLRRMEEEERLAEQQRA 1356

Query: 191  QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQ 250
            + +E   +V  ++E          Q  A  E + + LQQ++Q+E  RR+EA +   ++K+
Sbjct: 1357 EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKR 1416

Query: 251  EPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAG 310
              +E+ + + +Q  EA +   +                                   R  
Sbjct: 1417 SIQEELQ-QLRQSSEAEIQAKA-----------------------------------RQA 1440

Query: 311  EGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWE 370
            E    S   ++      EE+R     L A   Q  GA  E    L  L  R +    Q  
Sbjct: 1441 EAAERSRLRIE------EEIRVVRLQLEATERQRGGAEGE----LQALRARAEEAEAQKR 1490

Query: 371  RAQREQAQTARDLQE----LRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGR 426
            +AQ E  +  R +Q+     R    EL + V+  A +    +  L+ L  L+   EE  R
Sbjct: 1491 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1550

Query: 427  QFQNS--RRGPDLSMNLDRSHQGNCARCASQGSQLS--TESLQQLLDR---ALTSLVDEV 479
            + + +   R   + + L+ + +   A   S+ +  +  T  L++ L     A+  L +E 
Sbjct: 1551 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610

Query: 480  KQRGLTPACPSCQRLHKKI-LELER------QALAKHVRAEALSSTLRLAQDEALRAK 530
            ++R    A    +R  ++   ELER      +AL   ++AE ++    LAQ EA + K
Sbjct: 1611 ERRAQQQA--EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1666



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAE- 207
            ++++K   + Q +Q  QS    L    E  R+ AEE E   +Q +    +  R VE+AE 
Sbjct: 2057 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2116

Query: 208  IKTNVLKQNSALLEEK--LRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            +K +  +Q  A  + +     L+++ + E  RR +AE     +KQ  + + E  +K
Sbjct: 2117 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 92/423 (21%), Positives = 162/423 (38%), Gaps = 64/423 (15%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            ADI E L+ +        +    L E T R  + V+    E   L  + E+      ELE
Sbjct: 1889 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEE---EILALKASFEKAAAGKAELE 1945

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ------DETPRRQE 240
                +++ N     RS E AE++    +Q +A  E + R  ++++Q      +E  R+++
Sbjct: 1946 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 2005

Query: 241  AELQEPEE-KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLV 299
            A L+E E  K + EE +   E+ + E+         AA  +             + H   
Sbjct: 2006 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR--------LQAEEKAHAFA 2057

Query: 300  PAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV-SSLTARWHQEEGAVQEALRLLGGL 358
                       +     +Q LQ+  + +++LR E  ++  A    EE  VQ         
Sbjct: 2058 ---------VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ--------- 2099

Query: 359  GGRVDGFLGQWERAQREQAQTARDLQE---LRGRADELCTMVERSAVSVASLRSELEGLG 415
                         A+RE AQ+ R ++E   L+  A+E      ++  +   LR E E   
Sbjct: 2100 -------------AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2146

Query: 416  PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQ-LSTESLQQLLDRALTS 474
              +   E+   +    ++  D  M   +       R  +Q  Q L+T  LQ        +
Sbjct: 2147 ARRAQAEQAALR---QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2203

Query: 475  LVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLL 534
            L+DE  QR    A  + ++      ++E +  +  V+ E LS      + E    + L+L
Sbjct: 2204 LLDEELQRLKAEATEAARQRS----QVEEELFSVRVQMEELSKLKARIEAE---NRALIL 2256

Query: 535  TDK 537
             DK
Sbjct: 2257 RDK 2259



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 92/412 (22%), Positives = 144/412 (34%), Gaps = 110/412 (26%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            S  EKT ++ + +Q      + L E  ERR Q+  E E              R   + E+
Sbjct: 1584 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER------------AREEAEREL 1631

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            +   LK N A        L+ +LQ E   +Q++  Q   EKQ+ E ++E   + K E   
Sbjct: 1632 ERWQLKANEA--------LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE--- 1680

Query: 269  SWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIE 328
                                                   +A     ++EQEL+K      
Sbjct: 1681 --------------------------------------EQAVRQRELAEQELEK------ 1696

Query: 329  ELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRG 388
              +R+++  TA+  Q   A QE +RL                RA+ EQ +  R L E   
Sbjct: 1697 --QRQLAEGTAQ--QRLAAEQELIRL----------------RAETEQGEQQRQLLE--- 1733

Query: 389  RADELCTMVERSAVSVASLRSELEG-----LGPLKPILEEFGRQFQNSRRGPDLSMNLDR 443
               E    ++R A +    R ELE         ++ +L    R  + SR   + S     
Sbjct: 1734 ---EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1790

Query: 444  SHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG-----LTPACPSCQRLHKKI 498
            +  G     A + ++L   + +    R L    D  +QR      L     +     +  
Sbjct: 1791 AEAGRFRELAEEAARLRALAEEAKRQRQLAE-EDAARQRAEAERVLAEKLAAIGEATRLK 1849

Query: 499  LELERQALAKHVRAEALSSTLRLAQDEALRAKNL---LLTDKMKPEEKMATL 547
             E E     K    E L    RLA+DEA + + L       K   EE++A L
Sbjct: 1850 TEAEIALKEKEAENERLR---RLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1898



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 43/193 (22%), Positives = 86/193 (44%), Gaps = 18/193 (9%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            SL ++   + Q    L+    +  + + + +Q  EE +    Q+++   ++  S+E+A  
Sbjct: 2501 SLLQRERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2557

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            + +  ++     +E+L+ L+QQ      RRQ+ EL   E ++  E+ Q  EE+ +     
Sbjct: 2558 RQHEAEEGVRRKQEELQQLEQQ------RRQQEELLAEENQRLREQLQLLEEQHRAALAH 2611

Query: 269  SWN-SLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGM-----GPRAGEGPYVSEQELQK 322
            S   +    A ++  P    + D P+       +  G+       R  E   +S +ELQ+
Sbjct: 2612 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2671

Query: 323  LFTG---IEELRR 332
            L  G   ++EL R
Sbjct: 2672 LAQGHTTVDELAR 2684



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 67/295 (22%), Positives = 111/295 (37%), Gaps = 48/295 (16%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            A+  E L+ V + L + +    +  +   +  +  + LQ     + E + RR + A + +
Sbjct: 1356 AEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVDAQ 1412

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQDETPRRQEA 241
                 ++E   ++ +S E AEI+    +  +A      +EE++R ++ QL+    +R  A
Sbjct: 1413 QQKRSIQEELQQLRQSSE-AEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1471

Query: 242  ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPA 301
            E     E Q    + E  E QK +A      L      +         +  SR      A
Sbjct: 1472 E----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1527

Query: 302  GWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGR 361
                            +E Q+    +EELR +      R  Q E  V+ A ++   L   
Sbjct: 1528 A---------------REKQRALQALEELRLQAEEAERRLRQAE--VERARQVQVAL--- 1567

Query: 362  VDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSA----VSVASLRSELE 412
                    E AQR       +LQ  R    E    +ERS     V+VA LR E E
Sbjct: 1568 --------ETAQR---SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1611



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 47/201 (23%)

Query: 156  RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI-KTNVLK 214
            R+ + +  L+ E   L +  +  + ++EE++   +Q +E   + T++++ + + + + L 
Sbjct: 2447 RLREAIAELEREKEKLQQEAKLLQLKSEEMQ--TVQ-QEQLLQETQALQQSFLSEKDSLL 2503

Query: 215  QNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLG 274
            Q    +E++   L+Q  QDE      A+ Q+  E+Q+ +++Q  +E+Q+  A +      
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEV-----AKAQQLREEQQRQQQQMEQERQRLVASME----- 2553

Query: 275  PAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV 334
                           +   R H            A EG    ++ELQ+L    E+ RR+ 
Sbjct: 2554 ---------------EARRRQH-----------EAEEGVRRKQEELQQL----EQQRRQQ 2583

Query: 335  SSLTARWHQEEGAVQEALRLL 355
              L A   +E   ++E L+LL
Sbjct: 2584 EELLA---EENQRLREQLQLL 2601



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 159  QHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA 218
            Q  Q L  E       LE  RQ   E+     +LK    +++R+   AE      ++ + 
Sbjct: 2352 QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAE 2411

Query: 219  LLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPE-------EKQEPEEKQKPEAGL 268
             + EKL   +   Q++    Q  E+Q  +   + E       E +  +EK + EA L
Sbjct: 2412 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2468



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 86/449 (19%), Positives = 167/449 (37%), Gaps = 89/449 (19%)

Query: 126  DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQ--SECSVLS-----ENLERR 178
            + +  E+   +   +VR +++    +++   + + +Q L+  SE  + +     E  ER 
Sbjct: 1387 EREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERS 1446

Query: 179  RQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQD 233
            R   EE E   ++L+    +  R   + E++    +   A       +E+   L++Q+QD
Sbjct: 1447 RLRIEE-EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1505

Query: 234  ETPRRQEAELQ-------EPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPP 286
            E+ R+++AE++       E E  +E +   +  E+ + +A  +   L  A   +      
Sbjct: 1506 ESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA----- 1560

Query: 287  GSPDKPSRPHGLVPAGWGMGPRAGEGPYVS------------EQELQKLFTGIEELRREV 334
                        V        R+ E    S            E+ LQ+    + +LR E 
Sbjct: 1561 ----------RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1610

Query: 335  SSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELC 394
                 +  + E A +EA R L              ER Q +    A +   LR +A+E+ 
Sbjct: 1611 ERRAQQQAEAERAREEAEREL--------------ERWQLK----ANEALRLRLQAEEVA 1652

Query: 395  TMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCAS 454
                 +       + E E     +   EE     Q  R+       L++  Q       +
Sbjct: 1653 QQKSLAQAEAEKQKEEAEREARRRGKAEE-----QAVRQRELAEQELEKQRQ------LA 1701

Query: 455  QGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEA 514
            +G+     + +Q L R         +QR         Q L +++  L+R+A A   + + 
Sbjct: 1702 EGTAQQRLAAEQELIRLRAETEQGEQQR---------QLLEEELARLQREAAAATQKRQE 1752

Query: 515  LSSTLRLAQDEALRAKNLLLTDKMKPEEK 543
            L + L   + E      +LL  K + EE+
Sbjct: 1753 LEAELAKVRAE----MEVLLASKARAEEE 1777



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            ++R KD+     ++     + V    +  SV ++   R RQ AEE       L E   K 
Sbjct: 2255 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2314

Query: 200  T-RSVEDA---EIKTNVLKQNSALLEEKLRYLQ-------QQLQDET---PRRQEAELQE 245
              ++V++A   + +  +L+Q   L +E+ R LQ       QQL +ET    R  EAE Q 
Sbjct: 2315 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2374

Query: 246  PEEKQEPEEK 255
              E     E+
Sbjct: 2375 QLEMSAEAER 2384


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 93/418 (22%), Positives = 164/418 (39%), Gaps = 73/418 (17%)

Query: 131  EILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCI 190
            ++ SG  S +    D  T   E T   +Q+++        +SE L R  +E    E    
Sbjct: 1272 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIK-------FISETLRRMEEEERLAEQQRA 1324

Query: 191  QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQ 250
            + +E   +V  ++E          Q  A  E + + LQQ++Q+E  RR+EA +   ++K+
Sbjct: 1325 EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKR 1384

Query: 251  EPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAG 310
              +E+ + + +Q  EA +   +                                   R  
Sbjct: 1385 SIQEELQ-QLRQSSEAEIQAKA-----------------------------------RQA 1408

Query: 311  EGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWE 370
            E    S   ++      EE+R     L A   Q  GA  E    L  L  R +    Q  
Sbjct: 1409 EAAERSRLRIE------EEIRVVRLQLEATERQRGGAEGE----LQALRARAEEAEAQKR 1458

Query: 371  RAQREQAQTARDLQE----LRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGR 426
            +AQ E  +  R +Q+     R    EL + V+  A +    +  L+ L  L+   EE  R
Sbjct: 1459 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1518

Query: 427  QFQNS--RRGPDLSMNLDRSHQGNCARCASQGSQLS--TESLQQLLDR---ALTSLVDEV 479
            + + +   R   + + L+ + +   A   S+ +  +  T  L++ L     A+  L +E 
Sbjct: 1519 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1578

Query: 480  KQRGLTPACPSCQRLHKKI-LELER------QALAKHVRAEALSSTLRLAQDEALRAK 530
            ++R    A    +R  ++   ELER      +AL   ++AE ++    LAQ EA + K
Sbjct: 1579 ERRAQQQA--EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1634



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAE- 207
            ++++K   + Q +Q  QS    L    E  R+ AEE E   +Q +    +  R VE+AE 
Sbjct: 2025 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2084

Query: 208  IKTNVLKQNSALLEEK--LRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            +K +  +Q  A  + +     L+++ + E  RR +AE     +KQ  + + E  +K
Sbjct: 2085 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2140



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 92/423 (21%), Positives = 162/423 (38%), Gaps = 64/423 (15%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            ADI E L+ +        +    L E T R  + V+    E   L  + E+      ELE
Sbjct: 1857 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEE---EILALKASFEKAAAGKAELE 1913

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ------DETPRRQE 240
                +++ N     RS E AE++    +Q +A  E + R  ++++Q      +E  R+++
Sbjct: 1914 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 1973

Query: 241  AELQEPEE-KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLV 299
            A L+E E  K + EE +   E+ + E+         AA  +             + H   
Sbjct: 1974 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR--------LQAEEKAHAFA 2025

Query: 300  PAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV-SSLTARWHQEEGAVQEALRLLGGL 358
                       +     +Q LQ+  + +++LR E  ++  A    EE  VQ         
Sbjct: 2026 ---------VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ--------- 2067

Query: 359  GGRVDGFLGQWERAQREQAQTARDLQE---LRGRADELCTMVERSAVSVASLRSELEGLG 415
                         A+RE AQ+ R ++E   L+  A+E      ++  +   LR E E   
Sbjct: 2068 -------------AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2114

Query: 416  PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQ-LSTESLQQLLDRALTS 474
              +   E+   +    ++  D  M   +       R  +Q  Q L+T  LQ        +
Sbjct: 2115 ARRAQAEQAALR---QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2171

Query: 475  LVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLL 534
            L+DE  QR    A  + ++      ++E +  +  V+ E LS      + E    + L+L
Sbjct: 2172 LLDEELQRLKAEATEAARQRS----QVEEELFSVRVQMEELSKLKARIEAE---NRALIL 2224

Query: 535  TDK 537
             DK
Sbjct: 2225 RDK 2227



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 92/412 (22%), Positives = 144/412 (34%), Gaps = 110/412 (26%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            S  EKT ++ + +Q      + L E  ERR Q+  E E              R   + E+
Sbjct: 1552 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER------------AREEAEREL 1599

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            +   LK N A        L+ +LQ E   +Q++  Q   EKQ+ E ++E   + K E   
Sbjct: 1600 ERWQLKANEA--------LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE--- 1648

Query: 269  SWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIE 328
                                                   +A     ++EQEL+K      
Sbjct: 1649 --------------------------------------EQAVRQRELAEQELEK------ 1664

Query: 329  ELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRG 388
              +R+++  TA+  Q   A QE +RL                RA+ EQ +  R L E   
Sbjct: 1665 --QRQLAEGTAQ--QRLAAEQELIRL----------------RAETEQGEQQRQLLE--- 1701

Query: 389  RADELCTMVERSAVSVASLRSELEG-----LGPLKPILEEFGRQFQNSRRGPDLSMNLDR 443
               E    ++R A +    R ELE         ++ +L    R  + SR   + S     
Sbjct: 1702 ---EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1758

Query: 444  SHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG-----LTPACPSCQRLHKKI 498
            +  G     A + ++L   + +    R L    D  +QR      L     +     +  
Sbjct: 1759 AEAGRFRELAEEAARLRALAEEAKRQRQLAE-EDAARQRAEAERVLAEKLAAIGEATRLK 1817

Query: 499  LELERQALAKHVRAEALSSTLRLAQDEALRAKNL---LLTDKMKPEEKMATL 547
             E E     K    E L    RLA+DEA + + L       K   EE++A L
Sbjct: 1818 TEAEIALKEKEAENERLR---RLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1866



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 43/193 (22%), Positives = 86/193 (44%), Gaps = 18/193 (9%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            SL ++   + Q    L+    +  + + + +Q  EE +    Q+++   ++  S+E+A  
Sbjct: 2469 SLLQRERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2525

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            + +  ++     +E+L+ L+QQ      RRQ+ EL   E ++  E+ Q  EE+ +     
Sbjct: 2526 RQHEAEEGVRRKQEELQQLEQQ------RRQQEELLAEENQRLREQLQLLEEQHRAALAH 2579

Query: 269  SWN-SLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGM-----GPRAGEGPYVSEQELQK 322
            S   +    A ++  P    + D P+       +  G+       R  E   +S +ELQ+
Sbjct: 2580 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2639

Query: 323  LFTG---IEELRR 332
            L  G   ++EL R
Sbjct: 2640 LAQGHTTVDELAR 2652



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 67/295 (22%), Positives = 111/295 (37%), Gaps = 48/295 (16%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            A+  E L+ V + L + +    +  +   +  +  + LQ     + E + RR + A + +
Sbjct: 1324 AEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVDAQ 1380

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQDETPRRQEA 241
                 ++E   ++ +S E AEI+    +  +A      +EE++R ++ QL+    +R  A
Sbjct: 1381 QQKRSIQEELQQLRQSSE-AEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1439

Query: 242  ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPA 301
            E     E Q    + E  E QK +A      L      +         +  SR      A
Sbjct: 1440 E----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1495

Query: 302  GWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGR 361
                            +E Q+    +EELR +      R  Q E  V+ A ++   L   
Sbjct: 1496 A---------------REKQRALQALEELRLQAEEAERRLRQAE--VERARQVQVAL--- 1535

Query: 362  VDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSA----VSVASLRSELE 412
                    E AQR       +LQ  R    E    +ERS     V+VA LR E E
Sbjct: 1536 --------ETAQR---SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1579



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 47/201 (23%)

Query: 156  RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI-KTNVLK 214
            R+ + +  L+ E   L +  +  + ++EE++   +Q +E   + T++++ + + + + L 
Sbjct: 2415 RLREAIAELEREKEKLQQEAKLLQLKSEEMQ--TVQ-QEQLLQETQALQQSFLSEKDSLL 2471

Query: 215  QNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLG 274
            Q    +E++   L+Q  QDE      A+ Q+  E+Q+ +++Q  +E+Q+  A +      
Sbjct: 2472 QRERFIEQEKAKLEQLFQDEV-----AKAQQLREEQQRQQQQMEQERQRLVASME----- 2521

Query: 275  PAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV 334
                           +   R H            A EG    ++ELQ+L    E+ RR+ 
Sbjct: 2522 ---------------EARRRQH-----------EAEEGVRRKQEELQQL----EQQRRQQ 2551

Query: 335  SSLTARWHQEEGAVQEALRLL 355
              L A   +E   ++E L+LL
Sbjct: 2552 EELLA---EENQRLREQLQLL 2569



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 159  QHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA 218
            Q  Q L  E       LE  RQ   E+     +LK    +++R+   AE      ++ + 
Sbjct: 2320 QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAE 2379

Query: 219  LLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPE-------EKQEPEEKQKPEAGL 268
             + EKL   +   Q++    Q  E+Q  +   + E       E +  +EK + EA L
Sbjct: 2380 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2436



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 86/449 (19%), Positives = 167/449 (37%), Gaps = 89/449 (19%)

Query: 126  DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQ--SECSVLS-----ENLERR 178
            + +  E+   +   +VR +++    +++   + + +Q L+  SE  + +     E  ER 
Sbjct: 1355 EREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERS 1414

Query: 179  RQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQD 233
            R   EE E   ++L+    +  R   + E++    +   A       +E+   L++Q+QD
Sbjct: 1415 RLRIEE-EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1473

Query: 234  ETPRRQEAELQ-------EPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPP 286
            E+ R+++AE++       E E  +E +   +  E+ + +A  +   L  A   +      
Sbjct: 1474 ESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA----- 1528

Query: 287  GSPDKPSRPHGLVPAGWGMGPRAGEGPYVS------------EQELQKLFTGIEELRREV 334
                        V        R+ E    S            E+ LQ+    + +LR E 
Sbjct: 1529 ----------RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1578

Query: 335  SSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELC 394
                 +  + E A +EA R L              ER Q +    A +   LR +A+E+ 
Sbjct: 1579 ERRAQQQAEAERAREEAEREL--------------ERWQLK----ANEALRLRLQAEEVA 1620

Query: 395  TMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCAS 454
                 +       + E E     +   EE     Q  R+       L++  Q       +
Sbjct: 1621 QQKSLAQAEAEKQKEEAEREARRRGKAEE-----QAVRQRELAEQELEKQRQ------LA 1669

Query: 455  QGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEA 514
            +G+     + +Q L R         +QR         Q L +++  L+R+A A   + + 
Sbjct: 1670 EGTAQQRLAAEQELIRLRAETEQGEQQR---------QLLEEELARLQREAAAATQKRQE 1720

Query: 515  LSSTLRLAQDEALRAKNLLLTDKMKPEEK 543
            L + L   + E      +LL  K + EE+
Sbjct: 1721 LEAELAKVRAE----MEVLLASKARAEEE 1745



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            ++R KD+     ++     + V    +  SV ++   R RQ AEE       L E   K 
Sbjct: 2223 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2282

Query: 200  T-RSVEDA---EIKTNVLKQNSALLEEKLRYLQ-------QQLQDET---PRRQEAELQE 245
              ++V++A   + +  +L+Q   L +E+ R LQ       QQL +ET    R  EAE Q 
Sbjct: 2283 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2342

Query: 246  PEEKQEPEEK 255
              E     E+
Sbjct: 2343 QLEMSAEAER 2352


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 93/418 (22%), Positives = 164/418 (39%), Gaps = 73/418 (17%)

Query: 131  EILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCI 190
            ++ SG  S +    D  T   E T   +Q+++        +SE L R  +E    E    
Sbjct: 1441 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIK-------FISETLRRMEEEERLAEQQRA 1493

Query: 191  QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQ 250
            + +E   +V  ++E          Q  A  E + + LQQ++Q+E  RR+EA +   ++K+
Sbjct: 1494 EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKR 1553

Query: 251  EPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAG 310
              +E+ + + +Q  EA +   +                                   R  
Sbjct: 1554 SIQEELQ-QLRQSSEAEIQAKA-----------------------------------RQA 1577

Query: 311  EGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWE 370
            E    S   ++      EE+R     L A   Q  GA  E    L  L  R +    Q  
Sbjct: 1578 EAAERSRLRIE------EEIRVVRLQLEATERQRGGAEGE----LQALRARAEEAEAQKR 1627

Query: 371  RAQREQAQTARDLQE----LRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGR 426
            +AQ E  +  R +Q+     R    EL + V+  A +    +  L+ L  L+   EE  R
Sbjct: 1628 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1687

Query: 427  QFQNS--RRGPDLSMNLDRSHQGNCARCASQGSQLS--TESLQQLLDR---ALTSLVDEV 479
            + + +   R   + + L+ + +   A   S+ +  +  T  L++ L     A+  L +E 
Sbjct: 1688 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1747

Query: 480  KQRGLTPACPSCQRLHKKI-LELER------QALAKHVRAEALSSTLRLAQDEALRAK 530
            ++R    A    +R  ++   ELER      +AL   ++AE ++    LAQ EA + K
Sbjct: 1748 ERRAQQQA--EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1803



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAE- 207
            ++++K   + Q +Q  QS    L    E  R+ AEE E   +Q +    +  R VE+AE 
Sbjct: 2194 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2253

Query: 208  IKTNVLKQNSALLEEK--LRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            +K +  +Q  A  + +     L+++ + E  RR +AE     +KQ  + + E  +K
Sbjct: 2254 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2309



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 92/423 (21%), Positives = 162/423 (38%), Gaps = 64/423 (15%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            ADI E L+ +        +    L E T R  + V+    E   L  + E+      ELE
Sbjct: 2026 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEE---EILALKASFEKAAAGKAELE 2082

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ------DETPRRQE 240
                +++ N     RS E AE++    +Q +A  E + R  ++++Q      +E  R+++
Sbjct: 2083 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 2142

Query: 241  AELQEPEE-KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLV 299
            A L+E E  K + EE +   E+ + E+         AA  +             + H   
Sbjct: 2143 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR--------LQAEEKAHAFA 2194

Query: 300  PAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV-SSLTARWHQEEGAVQEALRLLGGL 358
                       +     +Q LQ+  + +++LR E  ++  A    EE  VQ         
Sbjct: 2195 ---------VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ--------- 2236

Query: 359  GGRVDGFLGQWERAQREQAQTARDLQE---LRGRADELCTMVERSAVSVASLRSELEGLG 415
                         A+RE AQ+ R ++E   L+  A+E      ++  +   LR E E   
Sbjct: 2237 -------------AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2283

Query: 416  PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQ-LSTESLQQLLDRALTS 474
              +   E+   +    ++  D  M   +       R  +Q  Q L+T  LQ        +
Sbjct: 2284 ARRAQAEQAALR---QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2340

Query: 475  LVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLL 534
            L+DE  QR    A  + ++      ++E +  +  V+ E LS      + E    + L+L
Sbjct: 2341 LLDEELQRLKAEATEAARQRS----QVEEELFSVRVQMEELSKLKARIEAE---NRALIL 2393

Query: 535  TDK 537
             DK
Sbjct: 2394 RDK 2396



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 92/412 (22%), Positives = 144/412 (34%), Gaps = 110/412 (26%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            S  EKT ++ + +Q      + L E  ERR Q+  E E              R   + E+
Sbjct: 1721 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER------------AREEAEREL 1768

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            +   LK N A        L+ +LQ E   +Q++  Q   EKQ+ E ++E   + K E   
Sbjct: 1769 ERWQLKANEA--------LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE--- 1817

Query: 269  SWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIE 328
                                                   +A     ++EQEL+K      
Sbjct: 1818 --------------------------------------EQAVRQRELAEQELEK------ 1833

Query: 329  ELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRG 388
              +R+++  TA+  Q   A QE +RL                RA+ EQ +  R L E   
Sbjct: 1834 --QRQLAEGTAQ--QRLAAEQELIRL----------------RAETEQGEQQRQLLE--- 1870

Query: 389  RADELCTMVERSAVSVASLRSELEG-----LGPLKPILEEFGRQFQNSRRGPDLSMNLDR 443
               E    ++R A +    R ELE         ++ +L    R  + SR   + S     
Sbjct: 1871 ---EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1927

Query: 444  SHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG-----LTPACPSCQRLHKKI 498
            +  G     A + ++L   + +    R L    D  +QR      L     +     +  
Sbjct: 1928 AEAGRFRELAEEAARLRALAEEAKRQRQLAE-EDAARQRAEAERVLAEKLAAIGEATRLK 1986

Query: 499  LELERQALAKHVRAEALSSTLRLAQDEALRAKNL---LLTDKMKPEEKMATL 547
             E E     K    E L    RLA+DEA + + L       K   EE++A L
Sbjct: 1987 TEAEIALKEKEAENERLR---RLAEDEAFQRRRLEEQAAQHKADIEERLAQL 2035



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 43/193 (22%), Positives = 86/193 (44%), Gaps = 18/193 (9%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            SL ++   + Q    L+    +  + + + +Q  EE +    Q+++   ++  S+E+A  
Sbjct: 2638 SLLQRERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2694

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            + +  ++     +E+L+ L+QQ      RRQ+ EL   E ++  E+ Q  EE+ +     
Sbjct: 2695 RQHEAEEGVRRKQEELQQLEQQ------RRQQEELLAEENQRLREQLQLLEEQHRAALAH 2748

Query: 269  SWN-SLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGM-----GPRAGEGPYVSEQELQK 322
            S   +    A ++  P    + D P+       +  G+       R  E   +S +ELQ+
Sbjct: 2749 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2808

Query: 323  LFTG---IEELRR 332
            L  G   ++EL R
Sbjct: 2809 LAQGHTTVDELAR 2821



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 67/295 (22%), Positives = 111/295 (37%), Gaps = 48/295 (16%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            A+  E L+ V + L + +    +  +   +  +  + LQ     + E + RR + A + +
Sbjct: 1493 AEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVDAQ 1549

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQDETPRRQEA 241
                 ++E   ++ +S E AEI+    +  +A      +EE++R ++ QL+    +R  A
Sbjct: 1550 QQKRSIQEELQQLRQSSE-AEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1608

Query: 242  ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPA 301
            E     E Q    + E  E QK +A      L      +         +  SR      A
Sbjct: 1609 E----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1664

Query: 302  GWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGR 361
                            +E Q+    +EELR +      R  Q E  V+ A ++   L   
Sbjct: 1665 A---------------REKQRALQALEELRLQAEEAERRLRQAE--VERARQVQVAL--- 1704

Query: 362  VDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSA----VSVASLRSELE 412
                    E AQR       +LQ  R    E    +ERS     V+VA LR E E
Sbjct: 1705 --------ETAQR---SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1748



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 47/201 (23%)

Query: 156  RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI-KTNVLK 214
            R+ + +  L+ E   L +  +  + ++EE++   +Q +E   + T++++ + + + + L 
Sbjct: 2584 RLREAIAELEREKEKLQQEAKLLQLKSEEMQ--TVQ-QEQLLQETQALQQSFLSEKDSLL 2640

Query: 215  QNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLG 274
            Q    +E++   L+Q  QDE      A+ Q+  E+Q+ +++Q  +E+Q+  A +      
Sbjct: 2641 QRERFIEQEKAKLEQLFQDEV-----AKAQQLREEQQRQQQQMEQERQRLVASME----- 2690

Query: 275  PAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV 334
                           +   R H            A EG    ++ELQ+L    E+ RR+ 
Sbjct: 2691 ---------------EARRRQH-----------EAEEGVRRKQEELQQL----EQQRRQQ 2720

Query: 335  SSLTARWHQEEGAVQEALRLL 355
              L A   +E   ++E L+LL
Sbjct: 2721 EELLA---EENQRLREQLQLL 2738



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 159  QHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA 218
            Q  Q L  E       LE  RQ   E+     +LK    +++R+   AE      ++ + 
Sbjct: 2489 QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAE 2548

Query: 219  LLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPE-------EKQEPEEKQKPEAGL 268
             + EKL   +   Q++    Q  E+Q  +   + E       E +  +EK + EA L
Sbjct: 2549 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2605



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 86/449 (19%), Positives = 167/449 (37%), Gaps = 89/449 (19%)

Query: 126  DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQ--SECSVLS-----ENLERR 178
            + +  E+   +   +VR +++    +++   + + +Q L+  SE  + +     E  ER 
Sbjct: 1524 EREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERS 1583

Query: 179  RQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQD 233
            R   EE E   ++L+    +  R   + E++    +   A       +E+   L++Q+QD
Sbjct: 1584 RLRIEE-EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1642

Query: 234  ETPRRQEAELQ-------EPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPP 286
            E+ R+++AE++       E E  +E +   +  E+ + +A  +   L  A   +      
Sbjct: 1643 ESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA----- 1697

Query: 287  GSPDKPSRPHGLVPAGWGMGPRAGEGPYVS------------EQELQKLFTGIEELRREV 334
                        V        R+ E    S            E+ LQ+    + +LR E 
Sbjct: 1698 ----------RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1747

Query: 335  SSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELC 394
                 +  + E A +EA R L              ER Q +    A +   LR +A+E+ 
Sbjct: 1748 ERRAQQQAEAERAREEAEREL--------------ERWQLK----ANEALRLRLQAEEVA 1789

Query: 395  TMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCAS 454
                 +       + E E     +   EE     Q  R+       L++  Q       +
Sbjct: 1790 QQKSLAQAEAEKQKEEAEREARRRGKAEE-----QAVRQRELAEQELEKQRQ------LA 1838

Query: 455  QGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEA 514
            +G+     + +Q L R         +QR         Q L +++  L+R+A A   + + 
Sbjct: 1839 EGTAQQRLAAEQELIRLRAETEQGEQQR---------QLLEEELARLQREAAAATQKRQE 1889

Query: 515  LSSTLRLAQDEALRAKNLLLTDKMKPEEK 543
            L + L   + E      +LL  K + EE+
Sbjct: 1890 LEAELAKVRAE----MEVLLASKARAEEE 1914



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            ++R KD+     ++     + V    +  SV ++   R RQ AEE       L E   K 
Sbjct: 2392 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2451

Query: 200  T-RSVEDA---EIKTNVLKQNSALLEEKLRYLQ-------QQLQDET---PRRQEAELQE 245
              ++V++A   + +  +L+Q   L +E+ R LQ       QQL +ET    R  EAE Q 
Sbjct: 2452 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2511

Query: 246  PEEKQEPEEK 255
              E     E+
Sbjct: 2512 QLEMSAEAER 2521


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 93/418 (22%), Positives = 164/418 (39%), Gaps = 73/418 (17%)

Query: 131  EILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCI 190
            ++ SG  S +    D  T   E T   +Q+++        +SE L R  +E    E    
Sbjct: 1282 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIK-------FISETLRRMEEEERLAEQQRA 1334

Query: 191  QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQ 250
            + +E   +V  ++E          Q  A  E + + LQQ++Q+E  RR+EA +   ++K+
Sbjct: 1335 EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKR 1394

Query: 251  EPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAG 310
              +E+ + + +Q  EA +   +                                   R  
Sbjct: 1395 SIQEELQ-QLRQSSEAEIQAKA-----------------------------------RQA 1418

Query: 311  EGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWE 370
            E    S   ++      EE+R     L A   Q  GA  E    L  L  R +    Q  
Sbjct: 1419 EAAERSRLRIE------EEIRVVRLQLEATERQRGGAEGE----LQALRARAEEAEAQKR 1468

Query: 371  RAQREQAQTARDLQE----LRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGR 426
            +AQ E  +  R +Q+     R    EL + V+  A +    +  L+ L  L+   EE  R
Sbjct: 1469 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1528

Query: 427  QFQNS--RRGPDLSMNLDRSHQGNCARCASQGSQLS--TESLQQLLDR---ALTSLVDEV 479
            + + +   R   + + L+ + +   A   S+ +  +  T  L++ L     A+  L +E 
Sbjct: 1529 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1588

Query: 480  KQRGLTPACPSCQRLHKKI-LELER------QALAKHVRAEALSSTLRLAQDEALRAK 530
            ++R    A    +R  ++   ELER      +AL   ++AE ++    LAQ EA + K
Sbjct: 1589 ERRAQQQA--EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1644



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAE- 207
            ++++K   + Q +Q  QS    L    E  R+ AEE E   +Q +    +  R VE+AE 
Sbjct: 2035 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2094

Query: 208  IKTNVLKQNSALLEEK--LRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            +K +  +Q  A  + +     L+++ + E  RR +AE     +KQ  + + E  +K
Sbjct: 2095 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2150



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 92/423 (21%), Positives = 162/423 (38%), Gaps = 64/423 (15%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            ADI E L+ +        +    L E T R  + V+    E   L  + E+      ELE
Sbjct: 1867 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEE---EILALKASFEKAAAGKAELE 1923

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ------DETPRRQE 240
                +++ N     RS E AE++    +Q +A  E + R  ++++Q      +E  R+++
Sbjct: 1924 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 1983

Query: 241  AELQEPEE-KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLV 299
            A L+E E  K + EE +   E+ + E+         AA  +             + H   
Sbjct: 1984 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR--------LQAEEKAHAFA 2035

Query: 300  PAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV-SSLTARWHQEEGAVQEALRLLGGL 358
                       +     +Q LQ+  + +++LR E  ++  A    EE  VQ         
Sbjct: 2036 ---------VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ--------- 2077

Query: 359  GGRVDGFLGQWERAQREQAQTARDLQE---LRGRADELCTMVERSAVSVASLRSELEGLG 415
                         A+RE AQ+ R ++E   L+  A+E      ++  +   LR E E   
Sbjct: 2078 -------------AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2124

Query: 416  PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQ-LSTESLQQLLDRALTS 474
              +   E+   +    ++  D  M   +       R  +Q  Q L+T  LQ        +
Sbjct: 2125 ARRAQAEQAALR---QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2181

Query: 475  LVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLL 534
            L+DE  QR    A  + ++      ++E +  +  V+ E LS      + E    + L+L
Sbjct: 2182 LLDEELQRLKAEATEAARQRS----QVEEELFSVRVQMEELSKLKARIEAE---NRALIL 2234

Query: 535  TDK 537
             DK
Sbjct: 2235 RDK 2237



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 92/412 (22%), Positives = 144/412 (34%), Gaps = 110/412 (26%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            S  EKT ++ + +Q      + L E  ERR Q+  E E              R   + E+
Sbjct: 1562 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER------------AREEAEREL 1609

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            +   LK N A        L+ +LQ E   +Q++  Q   EKQ+ E ++E   + K E   
Sbjct: 1610 ERWQLKANEA--------LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE--- 1658

Query: 269  SWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIE 328
                                                   +A     ++EQEL+K      
Sbjct: 1659 --------------------------------------EQAVRQRELAEQELEK------ 1674

Query: 329  ELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRG 388
              +R+++  TA+  Q   A QE +RL                RA+ EQ +  R L E   
Sbjct: 1675 --QRQLAEGTAQ--QRLAAEQELIRL----------------RAETEQGEQQRQLLE--- 1711

Query: 389  RADELCTMVERSAVSVASLRSELEG-----LGPLKPILEEFGRQFQNSRRGPDLSMNLDR 443
               E    ++R A +    R ELE         ++ +L    R  + SR   + S     
Sbjct: 1712 ---EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1768

Query: 444  SHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG-----LTPACPSCQRLHKKI 498
            +  G     A + ++L   + +    R L    D  +QR      L     +     +  
Sbjct: 1769 AEAGRFRELAEEAARLRALAEEAKRQRQLAE-EDAARQRAEAERVLAEKLAAIGEATRLK 1827

Query: 499  LELERQALAKHVRAEALSSTLRLAQDEALRAKNL---LLTDKMKPEEKMATL 547
             E E     K    E L    RLA+DEA + + L       K   EE++A L
Sbjct: 1828 TEAEIALKEKEAENERLR---RLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1876



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 43/193 (22%), Positives = 86/193 (44%), Gaps = 18/193 (9%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            SL ++   + Q    L+    +  + + + +Q  EE +    Q+++   ++  S+E+A  
Sbjct: 2479 SLLQRERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2535

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            + +  ++     +E+L+ L+QQ      RRQ+ EL   E ++  E+ Q  EE+ +     
Sbjct: 2536 RQHEAEEGVRRKQEELQQLEQQ------RRQQEELLAEENQRLREQLQLLEEQHRAALAH 2589

Query: 269  SWN-SLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGM-----GPRAGEGPYVSEQELQK 322
            S   +    A ++  P    + D P+       +  G+       R  E   +S +ELQ+
Sbjct: 2590 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2649

Query: 323  LFTG---IEELRR 332
            L  G   ++EL R
Sbjct: 2650 LAQGHTTVDELAR 2662



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 67/295 (22%), Positives = 111/295 (37%), Gaps = 48/295 (16%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            A+  E L+ V + L + +    +  +   +  +  + LQ     + E + RR + A + +
Sbjct: 1334 AEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVDAQ 1390

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQDETPRRQEA 241
                 ++E   ++ +S E AEI+    +  +A      +EE++R ++ QL+    +R  A
Sbjct: 1391 QQKRSIQEELQQLRQSSE-AEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1449

Query: 242  ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPA 301
            E     E Q    + E  E QK +A      L      +         +  SR      A
Sbjct: 1450 E----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1505

Query: 302  GWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGR 361
                            +E Q+    +EELR +      R  Q E  V+ A ++   L   
Sbjct: 1506 A---------------REKQRALQALEELRLQAEEAERRLRQAE--VERARQVQVAL--- 1545

Query: 362  VDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSA----VSVASLRSELE 412
                    E AQR       +LQ  R    E    +ERS     V+VA LR E E
Sbjct: 1546 --------ETAQR---SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1589



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 47/201 (23%)

Query: 156  RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI-KTNVLK 214
            R+ + +  L+ E   L +  +  + ++EE++   +Q +E   + T++++ + + + + L 
Sbjct: 2425 RLREAIAELEREKEKLQQEAKLLQLKSEEMQ--TVQ-QEQLLQETQALQQSFLSEKDSLL 2481

Query: 215  QNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLG 274
            Q    +E++   L+Q  QDE      A+ Q+  E+Q+ +++Q  +E+Q+  A +      
Sbjct: 2482 QRERFIEQEKAKLEQLFQDEV-----AKAQQLREEQQRQQQQMEQERQRLVASME----- 2531

Query: 275  PAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV 334
                           +   R H            A EG    ++ELQ+L    E+ RR+ 
Sbjct: 2532 ---------------EARRRQH-----------EAEEGVRRKQEELQQL----EQQRRQQ 2561

Query: 335  SSLTARWHQEEGAVQEALRLL 355
              L A   +E   ++E L+LL
Sbjct: 2562 EELLA---EENQRLREQLQLL 2579



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 159  QHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA 218
            Q  Q L  E       LE  RQ   E+     +LK    +++R+   AE      ++ + 
Sbjct: 2330 QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAE 2389

Query: 219  LLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPE-------EKQEPEEKQKPEAGL 268
             + EKL   +   Q++    Q  E+Q  +   + E       E +  +EK + EA L
Sbjct: 2390 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2446



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 86/449 (19%), Positives = 167/449 (37%), Gaps = 89/449 (19%)

Query: 126  DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQ--SECSVLS-----ENLERR 178
            + +  E+   +   +VR +++    +++   + + +Q L+  SE  + +     E  ER 
Sbjct: 1365 EREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERS 1424

Query: 179  RQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQD 233
            R   EE E   ++L+    +  R   + E++    +   A       +E+   L++Q+QD
Sbjct: 1425 RLRIEE-EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1483

Query: 234  ETPRRQEAELQ-------EPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPP 286
            E+ R+++AE++       E E  +E +   +  E+ + +A  +   L  A   +      
Sbjct: 1484 ESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA----- 1538

Query: 287  GSPDKPSRPHGLVPAGWGMGPRAGEGPYVS------------EQELQKLFTGIEELRREV 334
                        V        R+ E    S            E+ LQ+    + +LR E 
Sbjct: 1539 ----------RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1588

Query: 335  SSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELC 394
                 +  + E A +EA R L              ER Q +    A +   LR +A+E+ 
Sbjct: 1589 ERRAQQQAEAERAREEAEREL--------------ERWQLK----ANEALRLRLQAEEVA 1630

Query: 395  TMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCAS 454
                 +       + E E     +   EE     Q  R+       L++  Q       +
Sbjct: 1631 QQKSLAQAEAEKQKEEAEREARRRGKAEE-----QAVRQRELAEQELEKQRQ------LA 1679

Query: 455  QGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEA 514
            +G+     + +Q L R         +QR         Q L +++  L+R+A A   + + 
Sbjct: 1680 EGTAQQRLAAEQELIRLRAETEQGEQQR---------QLLEEELARLQREAAAATQKRQE 1730

Query: 515  LSSTLRLAQDEALRAKNLLLTDKMKPEEK 543
            L + L   + E      +LL  K + EE+
Sbjct: 1731 LEAELAKVRAE----MEVLLASKARAEEE 1755



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            ++R KD+     ++     + V    +  SV ++   R RQ AEE       L E   K 
Sbjct: 2233 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2292

Query: 200  T-RSVEDA---EIKTNVLKQNSALLEEKLRYLQ-------QQLQDET---PRRQEAELQE 245
              ++V++A   + +  +L+Q   L +E+ R LQ       QQL +ET    R  EAE Q 
Sbjct: 2293 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2352

Query: 246  PEEKQEPEEK 255
              E     E+
Sbjct: 2353 QLEMSAEAER 2362


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 93/418 (22%), Positives = 164/418 (39%), Gaps = 73/418 (17%)

Query: 131  EILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCI 190
            ++ SG  S +    D  T   E T   +Q+++        +SE L R  +E    E    
Sbjct: 1290 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIK-------FISETLRRMEEEERLAEQQRA 1342

Query: 191  QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQ 250
            + +E   +V  ++E          Q  A  E + + LQQ++Q+E  RR+EA +   ++K+
Sbjct: 1343 EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKR 1402

Query: 251  EPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAG 310
              +E+ + + +Q  EA +   +                                   R  
Sbjct: 1403 SIQEELQ-QLRQSSEAEIQAKA-----------------------------------RQA 1426

Query: 311  EGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWE 370
            E    S   ++      EE+R     L A   Q  GA  E    L  L  R +    Q  
Sbjct: 1427 EAAERSRLRIE------EEIRVVRLQLEATERQRGGAEGE----LQALRARAEEAEAQKR 1476

Query: 371  RAQREQAQTARDLQE----LRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGR 426
            +AQ E  +  R +Q+     R    EL + V+  A +    +  L+ L  L+   EE  R
Sbjct: 1477 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1536

Query: 427  QFQNS--RRGPDLSMNLDRSHQGNCARCASQGSQLS--TESLQQLLDR---ALTSLVDEV 479
            + + +   R   + + L+ + +   A   S+ +  +  T  L++ L     A+  L +E 
Sbjct: 1537 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1596

Query: 480  KQRGLTPACPSCQRLHKKI-LELER------QALAKHVRAEALSSTLRLAQDEALRAK 530
            ++R    A    +R  ++   ELER      +AL   ++AE ++    LAQ EA + K
Sbjct: 1597 ERRAQQQA--EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1652



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAE- 207
            ++++K   + Q +Q  QS    L    E  R+ AEE E   +Q +    +  R VE+AE 
Sbjct: 2043 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2102

Query: 208  IKTNVLKQNSALLEEK--LRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            +K +  +Q  A  + +     L+++ + E  RR +AE     +KQ  + + E  +K
Sbjct: 2103 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2158



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 92/423 (21%), Positives = 162/423 (38%), Gaps = 64/423 (15%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            ADI E L+ +        +    L E T R  + V+    E   L  + E+      ELE
Sbjct: 1875 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEE---EILALKASFEKAAAGKAELE 1931

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ------DETPRRQE 240
                +++ N     RS E AE++    +Q +A  E + R  ++++Q      +E  R+++
Sbjct: 1932 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 1991

Query: 241  AELQEPEE-KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLV 299
            A L+E E  K + EE +   E+ + E+         AA  +             + H   
Sbjct: 1992 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR--------LQAEEKAHAFA 2043

Query: 300  PAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV-SSLTARWHQEEGAVQEALRLLGGL 358
                       +     +Q LQ+  + +++LR E  ++  A    EE  VQ         
Sbjct: 2044 ---------VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ--------- 2085

Query: 359  GGRVDGFLGQWERAQREQAQTARDLQE---LRGRADELCTMVERSAVSVASLRSELEGLG 415
                         A+RE AQ+ R ++E   L+  A+E      ++  +   LR E E   
Sbjct: 2086 -------------AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2132

Query: 416  PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQ-LSTESLQQLLDRALTS 474
              +   E+   +    ++  D  M   +       R  +Q  Q L+T  LQ        +
Sbjct: 2133 ARRAQAEQAALR---QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2189

Query: 475  LVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLL 534
            L+DE  QR    A  + ++      ++E +  +  V+ E LS      + E    + L+L
Sbjct: 2190 LLDEELQRLKAEATEAARQRS----QVEEELFSVRVQMEELSKLKARIEAE---NRALIL 2242

Query: 535  TDK 537
             DK
Sbjct: 2243 RDK 2245



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 92/412 (22%), Positives = 144/412 (34%), Gaps = 110/412 (26%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            S  EKT ++ + +Q      + L E  ERR Q+  E E              R   + E+
Sbjct: 1570 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER------------AREEAEREL 1617

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            +   LK N A        L+ +LQ E   +Q++  Q   EKQ+ E ++E   + K E   
Sbjct: 1618 ERWQLKANEA--------LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE--- 1666

Query: 269  SWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIE 328
                                                   +A     ++EQEL+K      
Sbjct: 1667 --------------------------------------EQAVRQRELAEQELEK------ 1682

Query: 329  ELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRG 388
              +R+++  TA+  Q   A QE +RL                RA+ EQ +  R L E   
Sbjct: 1683 --QRQLAEGTAQ--QRLAAEQELIRL----------------RAETEQGEQQRQLLE--- 1719

Query: 389  RADELCTMVERSAVSVASLRSELEG-----LGPLKPILEEFGRQFQNSRRGPDLSMNLDR 443
               E    ++R A +    R ELE         ++ +L    R  + SR   + S     
Sbjct: 1720 ---EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1776

Query: 444  SHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG-----LTPACPSCQRLHKKI 498
            +  G     A + ++L   + +    R L    D  +QR      L     +     +  
Sbjct: 1777 AEAGRFRELAEEAARLRALAEEAKRQRQLAE-EDAARQRAEAERVLAEKLAAIGEATRLK 1835

Query: 499  LELERQALAKHVRAEALSSTLRLAQDEALRAKNL---LLTDKMKPEEKMATL 547
             E E     K    E L    RLA+DEA + + L       K   EE++A L
Sbjct: 1836 TEAEIALKEKEAENERLR---RLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1884



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 43/193 (22%), Positives = 86/193 (44%), Gaps = 18/193 (9%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            SL ++   + Q    L+    +  + + + +Q  EE +    Q+++   ++  S+E+A  
Sbjct: 2487 SLLQRERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2543

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            + +  ++     +E+L+ L+QQ      RRQ+ EL   E ++  E+ Q  EE+ +     
Sbjct: 2544 RQHEAEEGVRRKQEELQQLEQQ------RRQQEELLAEENQRLREQLQLLEEQHRAALAH 2597

Query: 269  SWN-SLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGM-----GPRAGEGPYVSEQELQK 322
            S   +    A ++  P    + D P+       +  G+       R  E   +S +ELQ+
Sbjct: 2598 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2657

Query: 323  LFTG---IEELRR 332
            L  G   ++EL R
Sbjct: 2658 LAQGHTTVDELAR 2670



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 67/295 (22%), Positives = 111/295 (37%), Gaps = 48/295 (16%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            A+  E L+ V + L + +    +  +   +  +  + LQ     + E + RR + A + +
Sbjct: 1342 AEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVDAQ 1398

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQDETPRRQEA 241
                 ++E   ++ +S E AEI+    +  +A      +EE++R ++ QL+    +R  A
Sbjct: 1399 QQKRSIQEELQQLRQSSE-AEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1457

Query: 242  ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPA 301
            E     E Q    + E  E QK +A      L      +         +  SR      A
Sbjct: 1458 E----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1513

Query: 302  GWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGR 361
                            +E Q+    +EELR +      R  Q E  V+ A ++   L   
Sbjct: 1514 A---------------REKQRALQALEELRLQAEEAERRLRQAE--VERARQVQVAL--- 1553

Query: 362  VDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSA----VSVASLRSELE 412
                    E AQR       +LQ  R    E    +ERS     V+VA LR E E
Sbjct: 1554 --------ETAQR---SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1597



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 47/201 (23%)

Query: 156  RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI-KTNVLK 214
            R+ + +  L+ E   L +  +  + ++EE++   +Q +E   + T++++ + + + + L 
Sbjct: 2433 RLREAIAELEREKEKLQQEAKLLQLKSEEMQ--TVQ-QEQLLQETQALQQSFLSEKDSLL 2489

Query: 215  QNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLG 274
            Q    +E++   L+Q  QDE      A+ Q+  E+Q+ +++Q  +E+Q+  A +      
Sbjct: 2490 QRERFIEQEKAKLEQLFQDEV-----AKAQQLREEQQRQQQQMEQERQRLVASME----- 2539

Query: 275  PAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV 334
                           +   R H            A EG    ++ELQ+L    E+ RR+ 
Sbjct: 2540 ---------------EARRRQH-----------EAEEGVRRKQEELQQL----EQQRRQQ 2569

Query: 335  SSLTARWHQEEGAVQEALRLL 355
              L A   +E   ++E L+LL
Sbjct: 2570 EELLA---EENQRLREQLQLL 2587



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 159  QHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA 218
            Q  Q L  E       LE  RQ   E+     +LK    +++R+   AE      ++ + 
Sbjct: 2338 QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAE 2397

Query: 219  LLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPE-------EKQEPEEKQKPEAGL 268
             + EKL   +   Q++    Q  E+Q  +   + E       E +  +EK + EA L
Sbjct: 2398 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2454



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 86/449 (19%), Positives = 167/449 (37%), Gaps = 89/449 (19%)

Query: 126  DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQ--SECSVLS-----ENLERR 178
            + +  E+   +   +VR +++    +++   + + +Q L+  SE  + +     E  ER 
Sbjct: 1373 EREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERS 1432

Query: 179  RQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQD 233
            R   EE E   ++L+    +  R   + E++    +   A       +E+   L++Q+QD
Sbjct: 1433 RLRIEE-EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1491

Query: 234  ETPRRQEAELQ-------EPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPP 286
            E+ R+++AE++       E E  +E +   +  E+ + +A  +   L  A   +      
Sbjct: 1492 ESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA----- 1546

Query: 287  GSPDKPSRPHGLVPAGWGMGPRAGEGPYVS------------EQELQKLFTGIEELRREV 334
                        V        R+ E    S            E+ LQ+    + +LR E 
Sbjct: 1547 ----------RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1596

Query: 335  SSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELC 394
                 +  + E A +EA R L              ER Q +    A +   LR +A+E+ 
Sbjct: 1597 ERRAQQQAEAERAREEAEREL--------------ERWQLK----ANEALRLRLQAEEVA 1638

Query: 395  TMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCAS 454
                 +       + E E     +   EE     Q  R+       L++  Q       +
Sbjct: 1639 QQKSLAQAEAEKQKEEAEREARRRGKAEE-----QAVRQRELAEQELEKQRQ------LA 1687

Query: 455  QGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEA 514
            +G+     + +Q L R         +QR         Q L +++  L+R+A A   + + 
Sbjct: 1688 EGTAQQRLAAEQELIRLRAETEQGEQQR---------QLLEEELARLQREAAAATQKRQE 1738

Query: 515  LSSTLRLAQDEALRAKNLLLTDKMKPEEK 543
            L + L   + E      +LL  K + EE+
Sbjct: 1739 LEAELAKVRAE----MEVLLASKARAEEE 1763



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            ++R KD+     ++     + V    +  SV ++   R RQ AEE       L E   K 
Sbjct: 2241 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2300

Query: 200  T-RSVEDA---EIKTNVLKQNSALLEEKLRYLQ-------QQLQDET---PRRQEAELQE 245
              ++V++A   + +  +L+Q   L +E+ R LQ       QQL +ET    R  EAE Q 
Sbjct: 2301 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2360

Query: 246  PEEKQEPEEK 255
              E     E+
Sbjct: 2361 QLEMSAEAER 2370


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 93/418 (22%), Positives = 164/418 (39%), Gaps = 73/418 (17%)

Query: 131  EILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCI 190
            ++ SG  S +    D  T   E T   +Q+++        +SE L R  +E    E    
Sbjct: 1331 KVQSGSESVIQEYVDLRTHYSELTTLTSQYIK-------FISETLRRMEEEERLAEQQRA 1383

Query: 191  QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQ 250
            + +E   +V  ++E          Q  A  E + + LQQ++Q+E  RR+EA +   ++K+
Sbjct: 1384 EERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKR 1443

Query: 251  EPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAG 310
              +E+ + + +Q  EA +   +                                   R  
Sbjct: 1444 SIQEELQ-QLRQSSEAEIQAKA-----------------------------------RQA 1467

Query: 311  EGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWE 370
            E    S   ++      EE+R     L A   Q  GA  E    L  L  R +    Q  
Sbjct: 1468 EAAERSRLRIE------EEIRVVRLQLEATERQRGGAEGE----LQALRARAEEAEAQKR 1517

Query: 371  RAQREQAQTARDLQE----LRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGR 426
            +AQ E  +  R +Q+     R    EL + V+  A +    +  L+ L  L+   EE  R
Sbjct: 1518 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAER 1577

Query: 427  QFQNS--RRGPDLSMNLDRSHQGNCARCASQGSQLS--TESLQQLLDR---ALTSLVDEV 479
            + + +   R   + + L+ + +   A   S+ +  +  T  L++ L     A+  L +E 
Sbjct: 1578 RLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1637

Query: 480  KQRGLTPACPSCQRLHKKI-LELER------QALAKHVRAEALSSTLRLAQDEALRAK 530
            ++R    A    +R  ++   ELER      +AL   ++AE ++    LAQ EA + K
Sbjct: 1638 ERRAQQQA--EAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQK 1693



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 31/116 (26%), Positives = 56/116 (48%), Gaps = 3/116 (2%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAE- 207
            ++++K   + Q +Q  QS    L    E  R+ AEE E   +Q +    +  R VE+AE 
Sbjct: 2084 AVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2143

Query: 208  IKTNVLKQNSALLEEK--LRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            +K +  +Q  A  + +     L+++ + E  RR +AE     +KQ  + + E  +K
Sbjct: 2144 LKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2199



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 92/423 (21%), Positives = 162/423 (38%), Gaps = 64/423 (15%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            ADI E L+ +        +    L E T R  + V+    E   L  + E+      ELE
Sbjct: 1916 ADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEE---EILALKASFEKAAAGKAELE 1972

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ------DETPRRQE 240
                +++ N     RS E AE++    +Q +A  E + R  ++++Q      +E  R+++
Sbjct: 1973 LELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRK 2032

Query: 241  AELQEPEE-KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLV 299
            A L+E E  K + EE +   E+ + E+         AA  +             + H   
Sbjct: 2033 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR--------LQAEEKAHAFA 2084

Query: 300  PAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV-SSLTARWHQEEGAVQEALRLLGGL 358
                       +     +Q LQ+  + +++LR E  ++  A    EE  VQ         
Sbjct: 2085 ---------VQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ--------- 2126

Query: 359  GGRVDGFLGQWERAQREQAQTARDLQE---LRGRADELCTMVERSAVSVASLRSELEGLG 415
                         A+RE AQ+ R ++E   L+  A+E      ++  +   LR E E   
Sbjct: 2127 -------------AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEA 2173

Query: 416  PLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQ-LSTESLQQLLDRALTS 474
              +   E+   +    ++  D  M   +       R  +Q  Q L+T  LQ        +
Sbjct: 2174 ARRAQAEQAALR---QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKN 2230

Query: 475  LVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLL 534
            L+DE  QR    A  + ++      ++E +  +  V+ E LS      + E    + L+L
Sbjct: 2231 LLDEELQRLKAEATEAARQRS----QVEEELFSVRVQMEELSKLKARIEAE---NRALIL 2283

Query: 535  TDK 537
             DK
Sbjct: 2284 RDK 2286



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 92/412 (22%), Positives = 144/412 (34%), Gaps = 110/412 (26%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            S  EKT ++ + +Q      + L E  ERR Q+  E E              R   + E+
Sbjct: 1611 SFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAER------------AREEAEREL 1658

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            +   LK N A        L+ +LQ E   +Q++  Q   EKQ+ E ++E   + K E   
Sbjct: 1659 ERWQLKANEA--------LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAE--- 1707

Query: 269  SWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIE 328
                                                   +A     ++EQEL+K      
Sbjct: 1708 --------------------------------------EQAVRQRELAEQELEK------ 1723

Query: 329  ELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRG 388
              +R+++  TA+  Q   A QE +RL                RA+ EQ +  R L E   
Sbjct: 1724 --QRQLAEGTAQ--QRLAAEQELIRL----------------RAETEQGEQQRQLLE--- 1760

Query: 389  RADELCTMVERSAVSVASLRSELEG-----LGPLKPILEEFGRQFQNSRRGPDLSMNLDR 443
               E    ++R A +    R ELE         ++ +L    R  + SR   + S     
Sbjct: 1761 ---EELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLE 1817

Query: 444  SHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRG-----LTPACPSCQRLHKKI 498
            +  G     A + ++L   + +    R L    D  +QR      L     +     +  
Sbjct: 1818 AEAGRFRELAEEAARLRALAEEAKRQRQLAE-EDAARQRAEAERVLAEKLAAIGEATRLK 1876

Query: 499  LELERQALAKHVRAEALSSTLRLAQDEALRAKNL---LLTDKMKPEEKMATL 547
             E E     K    E L    RLA+DEA + + L       K   EE++A L
Sbjct: 1877 TEAEIALKEKEAENERLR---RLAEDEAFQRRRLEEQAAQHKADIEERLAQL 1925



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 43/193 (22%), Positives = 86/193 (44%), Gaps = 18/193 (9%)

Query: 149  SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI 208
            SL ++   + Q    L+    +  + + + +Q  EE +    Q+++   ++  S+E+A  
Sbjct: 2528 SLLQRERFIEQEKAKLEQ---LFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2584

Query: 209  KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
            + +  ++     +E+L+ L+QQ      RRQ+ EL   E ++  E+ Q  EE+ +     
Sbjct: 2585 RQHEAEEGVRRKQEELQQLEQQ------RRQQEELLAEENQRLREQLQLLEEQHRAALAH 2638

Query: 269  SWN-SLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGM-----GPRAGEGPYVSEQELQK 322
            S   +    A ++  P    + D P+       +  G+       R  E   +S +ELQ+
Sbjct: 2639 SEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQR 2698

Query: 323  LFTG---IEELRR 332
            L  G   ++EL R
Sbjct: 2699 LAQGHTTVDELAR 2711



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 67/295 (22%), Positives = 111/295 (37%), Gaps = 48/295 (16%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELE 186
            A+  E L+ V + L + +    +  +   +  +  + LQ     + E + RR + A + +
Sbjct: 1383 AEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQR---MQEEVVRREEAAVDAQ 1439

Query: 187  GYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQDETPRRQEA 241
                 ++E   ++ +S E AEI+    +  +A      +EE++R ++ QL+    +R  A
Sbjct: 1440 QQKRSIQEELQQLRQSSE-AEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGA 1498

Query: 242  ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPA 301
            E     E Q    + E  E QK +A      L      +         +  SR      A
Sbjct: 1499 E----GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEA 1554

Query: 302  GWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGR 361
                            +E Q+    +EELR +      R  Q E  V+ A ++   L   
Sbjct: 1555 A---------------REKQRALQALEELRLQAEEAERRLRQAE--VERARQVQVAL--- 1594

Query: 362  VDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSA----VSVASLRSELE 412
                    E AQR       +LQ  R    E    +ERS     V+VA LR E E
Sbjct: 1595 --------ETAQR---SAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAE 1638



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 47/201 (23%)

Query: 156  RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI-KTNVLK 214
            R+ + +  L+ E   L +  +  + ++EE++   +Q +E   + T++++ + + + + L 
Sbjct: 2474 RLREAIAELEREKEKLQQEAKLLQLKSEEMQ--TVQ-QEQLLQETQALQQSFLSEKDSLL 2530

Query: 215  QNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLG 274
            Q    +E++   L+Q  QDE      A+ Q+  E+Q+ +++Q  +E+Q+  A +      
Sbjct: 2531 QRERFIEQEKAKLEQLFQDEV-----AKAQQLREEQQRQQQQMEQERQRLVASME----- 2580

Query: 275  PAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV 334
                           +   R H            A EG    ++ELQ+L    E+ RR+ 
Sbjct: 2581 ---------------EARRRQH-----------EAEEGVRRKQEELQQL----EQQRRQQ 2610

Query: 335  SSLTARWHQEEGAVQEALRLL 355
              L A   +E   ++E L+LL
Sbjct: 2611 EELLA---EENQRLREQLQLL 2628



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 28/117 (23%), Positives = 47/117 (40%), Gaps = 7/117 (5%)

Query: 159  QHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA 218
            Q  Q L  E       LE  RQ   E+     +LK    +++R+   AE      ++ + 
Sbjct: 2379 QMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAE 2438

Query: 219  LLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPE-------EKQEPEEKQKPEAGL 268
             + EKL   +   Q++    Q  E+Q  +   + E       E +  +EK + EA L
Sbjct: 2439 EIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKL 2495



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 86/449 (19%), Positives = 167/449 (37%), Gaps = 89/449 (19%)

Query: 126  DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQ--SECSVLS-----ENLERR 178
            + +  E+   +   +VR +++    +++   + + +Q L+  SE  + +     E  ER 
Sbjct: 1414 EREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERS 1473

Query: 179  RQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA-----LLEEKLRYLQQQLQD 233
            R   EE E   ++L+    +  R   + E++    +   A       +E+   L++Q+QD
Sbjct: 1474 RLRIEE-EIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQD 1532

Query: 234  ETPRRQEAELQ-------EPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPP 286
            E+ R+++AE++       E E  +E +   +  E+ + +A  +   L  A   +      
Sbjct: 1533 ESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERA----- 1587

Query: 287  GSPDKPSRPHGLVPAGWGMGPRAGEGPYVS------------EQELQKLFTGIEELRREV 334
                        V        R+ E    S            E+ LQ+    + +LR E 
Sbjct: 1588 ----------RQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEA 1637

Query: 335  SSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELC 394
                 +  + E A +EA R L              ER Q +    A +   LR +A+E+ 
Sbjct: 1638 ERRAQQQAEAERAREEAEREL--------------ERWQLK----ANEALRLRLQAEEVA 1679

Query: 395  TMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCAS 454
                 +       + E E     +   EE     Q  R+       L++  Q       +
Sbjct: 1680 QQKSLAQAEAEKQKEEAEREARRRGKAEE-----QAVRQRELAEQELEKQRQ------LA 1728

Query: 455  QGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEA 514
            +G+     + +Q L R         +QR         Q L +++  L+R+A A   + + 
Sbjct: 1729 EGTAQQRLAAEQELIRLRAETEQGEQQR---------QLLEEELARLQREAAAATQKRQE 1779

Query: 515  LSSTLRLAQDEALRAKNLLLTDKMKPEEK 543
            L + L   + E      +LL  K + EE+
Sbjct: 1780 LEAELAKVRAE----MEVLLASKARAEEE 1804



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 36/130 (27%), Positives = 57/130 (43%), Gaps = 14/130 (10%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            ++R KD+     ++     + V    +  SV ++   R RQ AEE       L E   K 
Sbjct: 2282 ILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKE 2341

Query: 200  T-RSVEDA---EIKTNVLKQNSALLEEKLRYLQ-------QQLQDET---PRRQEAELQE 245
              ++V++A   + +  +L+Q   L +E+ R LQ       QQL +ET    R  EAE Q 
Sbjct: 2342 KMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQR 2401

Query: 246  PEEKQEPEEK 255
              E     E+
Sbjct: 2402 QLEMSAEAER 2411


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 40/148 (27%), Positives = 73/148 (49%), Gaps = 5/148 (3%)

Query: 126 DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEEL 185
           +A++ E L    S     + ++  LK K  R    +  +Q+  + L E + R+ +E  E 
Sbjct: 227 NAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQT--NTLQEEMWRQEEELREQ 284

Query: 186 EGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQD-ETPRRQEAELQ 244
           E    + +E  W+    + + E K    ++     E++LR  +++L++ E   R++ EL+
Sbjct: 285 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELR 344

Query: 245 EPEEK-QEPEEKQ-EPEEKQKPEAGLSW 270
           E EE+ QE EEK  E EEK + +    W
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMW 372



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 66/265 (24%), Positives = 109/265 (41%), Gaps = 53/265 (20%)

Query: 140 LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
           L RA  ++++  +K +R   +++ L  E   LS  L R     EEL+    +L+E     
Sbjct: 181 LQRALSAVSTRHKKADR---YIEELTKERDALSLELYRNTITNEELKKKNAELQEKL--P 235

Query: 200 TRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPR----RQEAELQEPEEK-QEPEE 254
               E +EI+ NV +    L  E+ ++L  Q+Q  T +    RQE EL+E E+K ++ EE
Sbjct: 236 LAESEKSEIQLNVKELKRKL--ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE 293

Query: 255 KQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPY 314
           K   +E++  E                         +  +        W    R  E   
Sbjct: 294 KMWRQEERLRE-------------------------QEGKMREQEEKMWRQEKRLRE--- 325

Query: 315 VSEQEL---QKLFTGIEELRREVSSLTAR----WHQEEGAVQEALRLLGGLGGRVDGFLG 367
             E+EL   +K     +ELR +   +  +    W QEE   ++  ++      R +  L 
Sbjct: 326 -QEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKM-----WRQEERLW 379

Query: 368 QWERAQREQAQTARDLQELRGRADE 392
           + E+  REQ Q  RD +E     DE
Sbjct: 380 EQEKQMREQEQKMRDQEERMWEQDE 404



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 30/114 (26%), Positives = 61/114 (53%), Gaps = 9/114 (7%)

Query: 156 RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQ 215
           R+ +  + ++ E  ++ E  E+ +++ E+++    + +E  W+    +++ E K    ++
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQ----EQEEKMWEQEEKMQEQEEKMWEQEE 645

Query: 216 NSALLEEKLRYLQQQLQDETPRRQEAE-LQEPEEKQEPEEK---QEPEEKQKPE 265
                EEK+ + QQ+L ++  +  E E +QE E+ QE EEK   QE  EK+  E
Sbjct: 646 KMWEQEEKM-WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 19/113 (16%), Positives = 56/113 (49%)

Query: 151 KEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKT 210
           +EK  R  + ++  + +     E +  + ++  E E    + +E  W+  + + + E K 
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 392

Query: 211 NVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQK 263
              ++     +E+LR  +++++++    ++ E    E+K + +EK+  ++++K
Sbjct: 393 RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 28/124 (22%), Positives = 65/124 (52%), Gaps = 14/124 (11%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVT------RSV 203
           L E+  ++ +  Q ++ +   + E  ER R++ E +       +E  W+        + +
Sbjct: 378 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE-----QEKMWEQVEKMREEKKM 432

Query: 204 EDAEIKTNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
           ++ E KT   ++     EE++R  ++++  ++ET R QE ++Q+ EE    +E++E +++
Sbjct: 433 QEQEKKTRD-QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQ 491

Query: 262 QKPE 265
           + PE
Sbjct: 492 RLPE 495



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 13/100 (13%)

Query: 178 RRQEAEELEGYCIQLKENCW---KVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDE 234
           + QE E+++    + +E  W   K+ +  ++ E KT    Q     EE +R  ++++++E
Sbjct: 672 KMQEQEKMQ----EQEEKIWEQEKMEKKTQEQEKKT--WDQEKMREEESMREREKKMREE 725

Query: 235 TP--RRQEAELQEPEEKQEPEEKQ--EPEEKQKPEAGLSW 270
               R QE ++QE EEK + +E++  E EEK   +    W
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 29/89 (32%), Positives = 50/89 (56%), Gaps = 3/89 (3%)

Query: 176 ERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDET 235
           E+ R++ +++     ++++   K+    E  E KT   ++ +   EEK+R  ++  + E 
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596

Query: 236 PRRQEAEL-QEPEEK-QEPEEK-QEPEEK 261
             R+E E+ +E EEK QE EEK QE EEK
Sbjct: 597 KMREEEEMMREQEEKMQEQEEKMQEQEEK 625



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 27/118 (22%), Positives = 58/118 (49%), Gaps = 7/118 (5%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           L E+  ++ +H +  + E     +  E +  E E++E    + ++  W   +  E+  ++
Sbjct: 660 LPEQKEKLWEHEKMQEQE---KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716

Query: 210 TNVLKQNSALLEEKLRYLQQQLQD--ETPRRQEAELQEPEEKQEPEEKQEPEEKQKPE 265
               K      EE +R  ++++Q+  E  + QE E+ E EEK   +E++  E+++ PE
Sbjct: 717 EREKKMREE--EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE 772



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 28/133 (21%), Positives = 61/133 (45%), Gaps = 13/133 (9%)

Query: 142 RAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTR 201
           R ++    ++E+   + +  + +Q +   + E  E+  ++ E+++    + +E  W+   
Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ----EQEEKMWEQEE 645

Query: 202 SVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAE----LQEPEEK--QEPEEK 255
            + + E K   + +   L E+K +  + +   E  + QE E     QE  EK  QE E+K
Sbjct: 646 KMWEQEEK---MWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK 702

Query: 256 QEPEEKQKPEAGL 268
              +EK + E  +
Sbjct: 703 TWDQEKMREEESM 715



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 25/121 (20%), Positives = 62/121 (51%), Gaps = 10/121 (8%)

Query: 149 SLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEEL---EGYCIQLKENCWKVTRSVED 205
           S++E+  ++ +  + ++ +   + E  E+ +++ EE+   E    + +E  W+  R  E 
Sbjct: 714 SMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773

Query: 206 AEIKTNVLKQNSALLEEKLRYLQQQL---QDETPRRQEAELQEPEEKQEPEEKQEPEEKQ 262
            E     L ++  + E++  + Q++    Q+E  R QE +++  EEK   +E++   +++
Sbjct: 774 KE----KLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEE 829

Query: 263 K 263
           K
Sbjct: 830 K 830



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 28/123 (22%), Positives = 59/123 (47%), Gaps = 8/123 (6%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+ +++ +  + ++ +   + +  ER  ++ +E E      +E      R  E    +
Sbjct: 539 MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM----REEERMRER 594

Query: 210 TNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEK-QEPEEKQ-EPEEKQKPEAG 267
              +++   ++ E+   +Q+Q  +E  + QE ++ E EEK QE EEK  E EEK   +  
Sbjct: 595 EKKMREEEEMMREQEEKMQEQ--EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652

Query: 268 LSW 270
             W
Sbjct: 653 KMW 655



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 23/116 (19%), Positives = 55/116 (47%), Gaps = 2/116 (1%)

Query: 150 LKEKTNRVNQHVQSL--QSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAE 207
           L+E+   + +  + L  Q E     E ++ + ++  E E    + +E  W+    + + E
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382

Query: 208 IKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQK 263
            +    +Q     EE++    ++L+++  R +E E    + ++  EEK+  E+++K
Sbjct: 383 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKK 438



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 27/123 (21%), Positives = 53/123 (43%), Gaps = 9/123 (7%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEA--EELEGYCIQLKENCWKVTRSVEDAE 207
           ++E+  +     + +Q E  +     + R +E    E E    + +EN W+     E+ E
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ----EEKE 487

Query: 208 IKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAG 267
            +   L +    L E+ +    Q Q+E    QE ++++ EE    E+K   +EK + +  
Sbjct: 488 WQQQRLPEQKEKLWEQEK---MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544

Query: 268 LSW 270
             W
Sbjct: 545 QMW 547



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 26/119 (21%), Positives = 51/119 (42%), Gaps = 9/119 (7%)

Query: 151 KEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEI-- 208
           +EK  R  +     Q E     E     ++E E  +    + KE  W+  +  E  E   
Sbjct: 455 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 514

Query: 209 --KTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPE 265
             +  +  Q     +EK  + Q+++     R QE ++ E EEK   +E++  +++++ E
Sbjct: 515 EQEEKIRDQEEMWGQEKKMWRQEKM-----REQEDQMWEQEEKMRDQEQKMWDQEERME 568



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 28/138 (20%), Positives = 62/138 (44%), Gaps = 19/138 (13%)

Query: 142 RAKDSITSLKEKTNRVNQHVQSL--QSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
           + ++   +++E+  ++ +  +++  Q E     + L  ++++  E E    Q +E  W+ 
Sbjct: 458 KMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ-EEKIWEQ 516

Query: 200 TRSVEDAEIKTNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEKQEP----- 252
              + D E      ++     +EK+R  + Q+  Q+E  R QE ++ + EE+ E      
Sbjct: 517 EEKIRDQEEMWG--QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQ 574

Query: 253 -------EEKQEPEEKQK 263
                  EEK   EE+ +
Sbjct: 575 EKKTWDQEEKMREEERMR 592


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 35/131 (26%), Positives = 66/131 (50%), Gaps = 7/131 (5%)

Query: 144 KDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSV 203
           ++ I   +EK  R  + ++    +     E + R+ ++  E E    + +E  W+  + +
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEKKM 415

Query: 204 EDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAE--LQEPEEK-QEPEEK-QEPE 259
            + + K    ++     EEK+R L++ +QD+  + +E E  +QE EEK QE EEK Q  E
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475

Query: 260 EKQKPEAGLSW 270
           EK + +   +W
Sbjct: 476 EKIQEQEEKTW 486



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 59/284 (20%), Positives = 113/284 (39%), Gaps = 48/284 (16%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+  ++ +  + +  +   + E  E+R+++    E    +  E   +    +   E K
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435

Query: 210 TNVLKQNSALLEEKLRYLQQQLQDETPRRQEAE--LQEPEEK-QEPEEKQEPEEKQKPEA 266
              L++     EEKLR +++++Q+E  + QE E  +Q  EEK QE EEK   +EK   + 
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495

Query: 267 GLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTG 326
              W                                W    +  E     +++ +K+   
Sbjct: 496 EKIWEQ--------------------------EEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529

Query: 327 IEELRREVSSLTARWHQEEGAVQEALRL------LGGLGGRVD--GFLGQWERAQREQAQ 378
            E++R +   L   W QEE   ++ +RL      LG LG + +  G  G+   +QR    
Sbjct: 530 EEKMREQEVRL---WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTL 586

Query: 379 T--------ARDLQELRGRADELCTMVERSAVSVASLRSELEGL 414
           T        +++ Q L+ + D     +++   +   L S  E L
Sbjct: 587 TPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEAL 630



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/114 (26%), Positives = 60/114 (52%), Gaps = 3/114 (2%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           LKEK   + + ++ ++SE S +  N++  +++ E  +   + L +   +V       E++
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQ---LLLPQQQLQVEADRLGKELQ 272

Query: 210 TNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQK 263
           +   K  + + E +L  L  Q Q+E   RQE ++QE EEK   +E +  E+++K
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 14/137 (10%)

Query: 144 KDSITSLKEKTNRVNQHVQSLQSECSVLSENLER------RRQEAEELEGYCIQLKENCW 197
           K+    L+EK   V      +Q     L   LER      ++Q   E +    +L+    
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSA 276

Query: 198 KVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPR--RQEAELQEPEEK--QEPE 253
           K+   VE+ E+  N+L Q     EEK+   ++++Q++  +   QE +++E EEK  ++ E
Sbjct: 277 KLQAQVEENEL-WNLLNQQQ---EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE 332

Query: 254 EKQEPEEKQKPEAGLSW 270
           +  E EEK + +    W
Sbjct: 333 KMHEQEEKIREQEDKMW 349



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 24/96 (25%), Positives = 50/96 (52%), Gaps = 3/96 (3%)

Query: 173 ENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ 232
           E + R+ ++  E E    + ++  W+    + + E K    ++     EEK+R   +++Q
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384

Query: 233 DETPR--RQEAELQEPEEK-QEPEEKQEPEEKQKPE 265
           ++     RQE +++E EEK QE   +QE + +++ E
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 23/123 (18%), Positives = 62/123 (50%), Gaps = 2/123 (1%)

Query: 142 RAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTR 201
           + ++    ++E+   + +  + ++ +     E + R+ ++  E +    + +E  W+   
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434

Query: 202 SVEDAEIKTNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEKQEPEEKQEPE 259
            + + E      ++    +EEK++  ++++  Q+E  +RQE ++QE EEK   +EK   +
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494

Query: 260 EKQ 262
           E++
Sbjct: 495 EEK 497



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 27/117 (23%), Positives = 55/117 (47%), Gaps = 3/117 (2%)

Query: 147 ITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDA 206
           I   +EK  R  + +   + +     + + R+ ++  E E    + +E  W+    + + 
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 379

Query: 207 EIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEK--QEPEEKQEPEEK 261
           + K    ++     EEK+R  Q++ + E   RQE +++E +EK  ++ EE    EEK
Sbjct: 380 DEKIQEQEEEMWRQEEKIRE-QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 42/163 (25%), Positives = 74/163 (45%), Gaps = 30/163 (18%)

Query: 126 DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHV--QSLQSECSVLSENLE----RRR 179
           +A++ E L  V S     + ++  LK K  R    +  Q LQ E   L + L+    + +
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279

Query: 180 QEAEELEGYCI---QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETP 236
            + EE E + +   Q +E  W+    +++ E K         + E++L+  +Q+   E  
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEK---------MCEQELKIREQE---EKM 327

Query: 237 RRQEAELQEPEEK-QEPEEK--------QEPEEKQKPEAGLSW 270
            RQE ++ E EEK +E E+K        +E EEK + +    W
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 3/93 (3%)

Query: 173 ENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQL- 231
           E ++ + ++  E E    + +E  W+    + + E K    +      EEK+R  ++++ 
Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363

Query: 232 -QDETPRRQEAELQEPEEK-QEPEEKQEPEEKQ 262
            Q+E   RQE +++E +EK QE EE+   +E++
Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 35/131 (26%), Positives = 66/131 (50%), Gaps = 7/131 (5%)

Query: 144 KDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSV 203
           ++ I   +EK  R  + ++    +     E + R+ ++  E E    + +E  W+  + +
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE---KRQEKMWRQEKKM 415

Query: 204 EDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAE--LQEPEEK-QEPEEK-QEPE 259
            + + K    ++     EEK+R L++ +QD+  + +E E  +QE EEK QE EEK Q  E
Sbjct: 416 REQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475

Query: 260 EKQKPEAGLSW 270
           EK + +   +W
Sbjct: 476 EKIQEQEEKTW 486



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 59/284 (20%), Positives = 113/284 (39%), Gaps = 48/284 (16%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+  ++ +  + +  +   + E  E+R+++    E    +  E   +    +   E K
Sbjct: 376 IREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435

Query: 210 TNVLKQNSALLEEKLRYLQQQLQDETPRRQEAE--LQEPEEK-QEPEEKQEPEEKQKPEA 266
              L++     EEKLR +++++Q+E  + QE E  +Q  EEK QE EEK   +EK   + 
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495

Query: 267 GLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTG 326
              W                                W    +  E     +++ +K+   
Sbjct: 496 EKIWEQ--------------------------EEKMWRQEEKMWEQEEKMQEQEEKMQRQ 529

Query: 327 IEELRREVSSLTARWHQEEGAVQEALRL------LGGLGGRVD--GFLGQWERAQREQAQ 378
            E++R +   L   W QEE   ++ +RL      LG LG + +  G  G+   +QR    
Sbjct: 530 EEKMREQEVRL---WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTL 586

Query: 379 T--------ARDLQELRGRADELCTMVERSAVSVASLRSELEGL 414
           T        +++ Q L+ + D     +++   +   L S  E L
Sbjct: 587 TPILQVELKSQEAQSLQQQQDHYRGHLQQYVAAYQQLASGKEAL 630



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 30/114 (26%), Positives = 60/114 (52%), Gaps = 3/114 (2%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           LKEK   + + ++ ++SE S +  N++  +++ E  +   + L +   +V       E++
Sbjct: 216 LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQ---LLLPQQQLQVEADRLGKELQ 272

Query: 210 TNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQK 263
           +   K  + + E +L  L  Q Q+E   RQE ++QE EEK   +E +  E+++K
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 36/137 (26%), Positives = 64/137 (46%), Gaps = 14/137 (10%)

Query: 144 KDSITSLKEKTNRVNQHVQSLQSECSVLSENLER------RRQEAEELEGYCIQLKENCW 197
           K+    L+EK   V      +Q     L   LER      ++Q   E +    +L+    
Sbjct: 217 KEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSA 276

Query: 198 KVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPR--RQEAELQEPEEK--QEPE 253
           K+   VE+ E+  N+L Q     EEK+   ++++Q++  +   QE +++E EEK  ++ E
Sbjct: 277 KLQAQVEENEL-WNLLNQQQ---EEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEE 332

Query: 254 EKQEPEEKQKPEAGLSW 270
           +  E EEK + +    W
Sbjct: 333 KMHEQEEKIREQEDKMW 349



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 24/96 (25%), Positives = 50/96 (52%), Gaps = 3/96 (3%)

Query: 173 ENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQ 232
           E + R+ ++  E E    + ++  W+    + + E K    ++     EEK+R   +++Q
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384

Query: 233 DETPR--RQEAELQEPEEK-QEPEEKQEPEEKQKPE 265
           ++     RQE +++E EEK QE   +QE + +++ E
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 23/123 (18%), Positives = 62/123 (50%), Gaps = 2/123 (1%)

Query: 142 RAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTR 201
           + ++    ++E+   + +  + ++ +     E + R+ ++  E +    + +E  W+   
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434

Query: 202 SVEDAEIKTNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEKQEPEEKQEPE 259
            + + E      ++    +EEK++  ++++  Q+E  +RQE ++QE EEK   +EK   +
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494

Query: 260 EKQ 262
           E++
Sbjct: 495 EEK 497



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 27/117 (23%), Positives = 55/117 (47%), Gaps = 3/117 (2%)

Query: 147 ITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDA 206
           I   +EK  R  + +   + +     + + R+ ++  E E    + +E  W+    + + 
Sbjct: 320 IREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 379

Query: 207 EIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEK--QEPEEKQEPEEK 261
           + K    ++     EEK+R  Q++ + E   RQE +++E +EK  ++ EE    EEK
Sbjct: 380 DEKIQEQEEEMWRQEEKIRE-QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 42/163 (25%), Positives = 74/163 (45%), Gaps = 30/163 (18%)

Query: 126 DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHV--QSLQSECSVLSENLE----RRR 179
           +A++ E L  V S     + ++  LK K  R    +  Q LQ E   L + L+    + +
Sbjct: 220 NAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ 279

Query: 180 QEAEELEGYCI---QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETP 236
            + EE E + +   Q +E  W+    +++ E K         + E++L+  +Q+   E  
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEK---------MCEQELKIREQE---EKM 327

Query: 237 RRQEAELQEPEEK-QEPEEK--------QEPEEKQKPEAGLSW 270
            RQE ++ E EEK +E E+K        +E EEK + +    W
Sbjct: 328 WRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMW 370



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 3/93 (3%)

Query: 173 ENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQL- 231
           E ++ + ++  E E    + +E  W+    + + E K    +      EEK+R  ++++ 
Sbjct: 304 EKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIR 363

Query: 232 -QDETPRRQEAELQEPEEK-QEPEEKQEPEEKQ 262
            Q+E   RQE +++E +EK QE EE+   +E++
Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK 396


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 39/148 (26%), Positives = 73/148 (49%), Gaps = 5/148 (3%)

Query: 126 DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEEL 185
           +A++ E L    S     + ++  LK K  R    +  +Q+  + L E + R+ +E  E 
Sbjct: 189 NAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQT--NTLQEEMWRQEEELREQ 246

Query: 186 EGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQD-ETPRRQEAELQ 244
           E    + +E  W+    + + E K    ++     E++LR  +++L++ E   R++ +L+
Sbjct: 247 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLR 306

Query: 245 EPEEK-QEPEEKQ-EPEEKQKPEAGLSW 270
           E EE+ QE EEK  E EEK + +    W
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMW 334



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 35/145 (24%), Positives = 72/145 (49%), Gaps = 7/145 (4%)

Query: 128 DITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEG 187
           ++T+    ++  L R   +   LK+K   + + ++  +SE S +  N++  +++ E  + 
Sbjct: 163 ELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKF 222

Query: 188 YCIQ-----LKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQL--QDETPRRQE 240
              Q     L+E  W+    + + E K    ++     EE+LR  + ++  Q+E  RRQE
Sbjct: 223 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE 282

Query: 241 AELQEPEEKQEPEEKQEPEEKQKPE 265
             L+E E++   +EK+  E+K+  E
Sbjct: 283 KRLREQEKELREQEKELREQKKLRE 307



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 24/121 (19%), Positives = 65/121 (53%), Gaps = 7/121 (5%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEEL---EGYCIQLKENCWKVTRSVEDA 206
           ++E+  ++ +  + ++ +   + E  E+ R++ E++   E    + +E  W+    + + 
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621

Query: 207 EIKTNVLKQNSALLEEKLRYLQQQL----QDETPRRQEAELQEPEEKQEPEEKQEPEEKQ 262
           E +  + +Q   + E++ +  +Q+     Q+E  R QE +++E EEK + +E++  E+++
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681

Query: 263 K 263
           K
Sbjct: 682 K 682



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 41/131 (31%), Positives = 70/131 (53%), Gaps = 12/131 (9%)

Query: 140 LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
           L RA  ++++  +K +R   +++ L  E   LS  L R     EEL+    +L+E   ++
Sbjct: 143 LQRALSAVSTWHKKADR---YIEELTKERDALSLELYRNTITNEELKKKNAELQEKL-RL 198

Query: 200 TRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPR----RQEAELQEPEEK-QEPEE 254
             S E +EI+ NV +    L  E+ ++L  Q+Q  T +    RQE EL+E E+K ++ EE
Sbjct: 199 AES-EKSEIQLNVKELKRKL--ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEE 255

Query: 255 KQEPEEKQKPE 265
           K   +E++  E
Sbjct: 256 KMWRQEERLRE 266



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 28/116 (24%), Positives = 62/116 (53%), Gaps = 5/116 (4%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+  ++ +  + +Q +   + E  E+  ++ EE +    + +E  W+    +++ E K
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQ--EQEEMMWEQEEKMQEQEEK 647

Query: 210 TNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEK-QEPEEKQEPEEKQ 262
               ++     EEK+R  ++++  Q+E  R QE ++Q  EEK +E EEK   +E++
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEK 703



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 26/112 (23%), Positives = 60/112 (53%), Gaps = 9/112 (8%)

Query: 156 RVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQ 215
           R+ +  + ++ E  ++ E  E+ +++ E++     + +E  W+    +++ E K  + +Q
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMR----EQEEKMWEQEEKMQEQEEK--MWEQ 614

Query: 216 NSALLEEKLRYLQQQLQDETPRRQEAELQEPEEK--QEPEEKQEPEEKQKPE 265
              + E++     Q+ Q+E    QE ++QE EEK  ++ E+ +E EEK + +
Sbjct: 615 EEKMWEQEEEDKMQE-QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665



 Score = 38.5 bits (88), Expect = 0.018
 Identities = 25/116 (21%), Positives = 56/116 (48%), Gaps = 1/116 (0%)

Query: 151 KEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKT 210
           +EK  R  + ++  + +     E +  + ++  E E    + +E  W+  + + + E K 
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354

Query: 211 NVLKQNSALLEEKLRYLQQQLQD-ETPRRQEAELQEPEEKQEPEEKQEPEEKQKPE 265
              ++     +E+LR  ++++++ E    QE ++QE E  +E E+K   EE+   E
Sbjct: 355 RDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMRE 410



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 47/203 (23%), Positives = 85/203 (41%), Gaps = 36/203 (17%)

Query: 159 QHVQSLQSECSVLSENLERRRQEAEEL----EGYCIQLKENCWKVTRSVEDAEIKTNVLK 214
           Q  +  + E  +  +  E + QE EE+    E    + +E  W+    + + E K    +
Sbjct: 607 QEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE 666

Query: 215 QNSALLEEKLRYLQQQLQ--DETPRRQEAELQEPEEK------------------QEPEE 254
           +     EEK+R  ++++Q  +E  R QE +++  EEK                  +E  E
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE 726

Query: 255 KQE--PEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEG 312
           K+E   ++K+K +  L  +       S+ C  P       S    + PA    G  AGEG
Sbjct: 727 KEERIRDQKEKMQERLPEHE---ERCSEPCLPPSKVLCNMSHTGSVEPA----GGEAGEG 779

Query: 313 ---PYVSEQELQKLFTGIEELRR 332
                 + QE+ +LF G++  ++
Sbjct: 780 SPQDNPTAQEIMQLFCGMKNAQQ 802



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 25/118 (21%), Positives = 59/118 (50%), Gaps = 22/118 (18%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           L E+  ++ +  Q ++ +   + E  ER R++ E +       +E  W+    +++    
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMRE-----QEKMWEQEEKMQE---- 390

Query: 210 TNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPE 265
                      EE++R  ++++  ++ET R QE ++Q+ EE    +E++E ++++ PE
Sbjct: 391 -----------EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 437



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 26/113 (23%), Positives = 57/113 (50%), Gaps = 7/113 (6%)

Query: 152 EKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTN 211
           E+  ++    Q +  +   + E  ER R++ E +       ++  W+    + + E KT 
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMRE-----QKKMWQQEEKMRE-EKKTQ 543

Query: 212 VLKQNSALLEEKLRYLQQQLQDETPRRQEAEL-QEPEEKQEPEEKQEPEEKQK 263
             ++ +   EEK+R  ++  + E   R+E E+ +E EEK + +E++  E+++K
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 29/124 (23%), Positives = 56/124 (45%), Gaps = 5/124 (4%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           L+EK  R+ +  +  + E  +  E   R R++    E   ++ +E   K+ +  E+   +
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE--KMQKQEENMWEQ 425

Query: 210 TNVLKQNSALLEEKLRYLQQ---QLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEA 266
                Q   L E+K +  +Q   Q Q+E    QE ++++ EE    E+K   +EK + + 
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485

Query: 267 GLSW 270
              W
Sbjct: 486 DQMW 489



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 26/122 (21%), Positives = 57/122 (46%), Gaps = 14/122 (11%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+  ++ +  + ++ +  +  +  +  RQE         + ++  W+    + D E K
Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR------EQEDQMWEQEEKMRDQEQK 501

Query: 210 T-----NVLKQNSALLE--EKLRYLQQQLQDETPRRQEAELQEPEEKQ-EPEEKQEPEEK 261
                  + +Q+  L E  E++R  ++  Q E   R+E + QE E+K  + EEK   EE+
Sbjct: 502 MWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER 561

Query: 262 QK 263
            +
Sbjct: 562 MR 563



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 22/116 (18%), Positives = 56/116 (48%), Gaps = 2/116 (1%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAE--ELEGYCIQLKENCWKVTRSVEDAE 207
           L+E+   + +  + L+ +  +  +  + + QE +  E E    + +E  W+    + + E
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344

Query: 208 IKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQK 263
            +    +Q     EE++    ++L+++  R +E E    +E++  EE++  E ++K
Sbjct: 345 KQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK 400



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 9/60 (15%)

Query: 221 EEKLRYLQQQL---------QDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWN 271
           EEK+R  +Q++         QDE  R +E  ++E ++  + EEK   E+K + +   +W+
Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD 551



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 26/134 (19%), Positives = 59/134 (44%), Gaps = 13/134 (9%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           L+EK  R+ +  +  Q E  +  E   + +++    +   ++ +E   +  + + + E  
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 575

Query: 210 TNVLKQNSALLEEKLRYLQQQLQDETPRRQEAEL-----------QEPEEKQEPEEKQ-- 256
               ++     EEK+R  ++++ ++  + QE E            QE E+K + +E+   
Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW 635

Query: 257 EPEEKQKPEAGLSW 270
           E EEK + +    W
Sbjct: 636 EQEEKMQEQEEKMW 649


>gi|81295809 pericentrin [Homo sapiens]
          Length = 3336

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 97/450 (21%), Positives = 185/450 (41%), Gaps = 54/450 (12%)

Query: 126  DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHV----QSLQSECSVLSENLERRRQE 181
            ++++ E LS  + G  +  +++T+L+++   +++H+    Q +  + +      E  +QE
Sbjct: 1440 ESELEEQLSQ-HRGCAKQAEAVTALEQQVASLDKHLRNQRQFMDEQAAEREHEREEFQQE 1498

Query: 182  AEELEGYCIQL-KENCWKVTRSVE-----DAEIKTNVLKQ-----NSALLEEKLRYLQQQ 230
             + LEG   Q  K   W    S +     + E+    L++     N   ++++    Q  
Sbjct: 1499 IQRLEGQLRQAAKPQPWGPRDSQQAPLDGEVELLQQKLREKLDEFNELAIQKESADRQVL 1558

Query: 231  LQDETPRRQE----------AELQEPEEKQEP-----EEKQEPEEKQKPEAGLSWNSLGP 275
            +Q+E  +R E          A+LQE  EKQ+      E+ +E  +KQ+  + L  ++L  
Sbjct: 1559 MQEEEIKRLEEMNINIRKKVAQLQEEVEKQKNIVKGLEQDKEVLKKQQMSSLLLASTLQS 1618

Query: 276  AATSQGCPGPP-GSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREV 334
               +  CP PP GSP  P  P   +        R        +++L+K+   +E    E+
Sbjct: 1619 TLDAGRCPEPPSGSP--PEGPEIQLEVTQRALLRRESEVLDLKEQLEKMKGDLESKNEEI 1676

Query: 335  SSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRAD-EL 393
              L  +   +      +LR L      +     +    +  +A T  +LQE + R   E 
Sbjct: 1677 LHLNLKLDMQNSQTAVSLRELEEENTSLKVIYTRSSEIEELKA-TIENLQENQKRLQKEK 1735

Query: 394  CTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCA 453
               +E+    +  L+ EL  +GP+         +  +S+ G  L   L  S  G     A
Sbjct: 1736 AEEIEQLHEVIEKLQHELSLMGPVV-------HEVSDSQAG-SLQSELLCSQAGGPRGQA 1787

Query: 454  SQGSQLSTESLQQLLDRALT------SLVDEVKQRGLTPACPSCQRLHKKILELERQALA 507
             QG   +    ++ L R L       S   E  Q+ L  A  + +    ++ ELER    
Sbjct: 1788 LQGELEAALEAKEALSRLLADQERRHSQALEALQQRLQGAEEAAE---LQLAELERNVAL 1844

Query: 508  KHVRAEALSSTLRLAQDEALRAKNLLLTDK 537
            +    E ++S ++   + AL+AK   + ++
Sbjct: 1845 REAEVEDMASRIQ-EFEAALKAKEATIAER 1873



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 62/306 (20%), Positives = 112/306 (36%), Gaps = 16/306 (5%)

Query: 146  SITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVED 205
            +++  +EK N V + + + Q+    L  +L   RQ++E+L     ++++   ++   +  
Sbjct: 2584 TLSEEQEKANSVQKLLAAEQTVVRDLKSDLCESRQKSEQLSRSLCEVQQEVLQLRSMLSS 2643

Query: 206  AEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPE 265
             E +     Q     + K R LQ QL++E  R  + E Q  +  +E     E +  Q   
Sbjct: 2644 KENELKAALQELESEQGKGRALQSQLEEEQLRHLQRESQSAKALEELRASLETQRAQSSR 2703

Query: 266  AGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFT 325
              ++      A  +           + SR   L+           +     +    +L  
Sbjct: 2704 LCVALKHEQTAKDNL----QKELRIEHSRCEALLAQERSQLSELQKDLAAEKSRTLELSE 2759

Query: 326  GIEELRREVSSLTARW-----HQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTA 380
             +   R     L+ R      HQ+  A    L+ L     RV       E+ Q+   Q  
Sbjct: 2760 ALRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEEKSRVVDLQAMLEKVQQ---QAL 2816

Query: 381  RDLQELRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPD-LSM 439
               Q+L   A + C  + R     A+L+S +E L   K    E     +  R  P  L  
Sbjct: 2817 HSQQQLEAEAQKHCEALRREKEVSATLKSTVEALHTQK---RELRCSLEREREKPAWLQA 2873

Query: 440  NLDRSH 445
             L++SH
Sbjct: 2874 ELEQSH 2879



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 6/110 (5%)

Query: 125  DDADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEE 184
            + AD+ E+L+G      R    + SL+ +  +  Q   +L+ EC+ L    E    +AE 
Sbjct: 1343 ETADLKEVLAGKEDSEHRLVLELESLRRQLQQAAQEQAALREECTRLWSRGEATATDAEA 1402

Query: 185  LEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDE 234
             E    +  E+  K     E +E +    K  SALL + ++ L+ +L+++
Sbjct: 1403 REAALRKEVEDLTK-----EQSETRKQAEKDRSALLSQ-MKILESELEEQ 1446



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 21/138 (15%)

Query: 133 LSGVNSGLVRAKDSITSLKEKTNRV----NQHVQSLQSECSVLSENLERRRQEAEELEG- 187
           L GV  G + A        E+  RV     +H   L    + L E +E  + E   L G 
Sbjct: 652 LQGVQDGDLEADT------ERAARVLGLETEHKVQLSLLQTELKEEIELLKIENRNLYGK 705

Query: 188 --YCIQLKENCWKVTRS-VED-------AEIKTNVLKQNSALLEEKLRYLQQQLQDETPR 237
             +  +LK++  KV  + +ED       A+ KT ++KQ     E   + ++++LQ E   
Sbjct: 706 LQHETRLKDDLEKVKHNLIEDHQKELNNAKQKTELMKQEFQRKETDWKVMKEELQREAEE 765

Query: 238 RQEAELQEPEEKQEPEEK 255
           +    L E  EK E E++
Sbjct: 766 KLTLMLLELREKAESEKQ 783


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 81/409 (19%), Positives = 155/409 (37%), Gaps = 49/409 (11%)

Query: 129 ITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGY 188
           + E LS V +     K     L+++     QH   LQSE + L   L    ++  E  G 
Sbjct: 377 LKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHG- 435

Query: 189 CIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEE 248
             +LKE     +  + D E       Q  A L+ KL  L++QL+++     E + Q  + 
Sbjct: 436 --RLKEQRQLSSEKLMDKE-------QQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKT 486

Query: 249 KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPR 308
           KQ+ +E+Q  ++    +   + N L       G        DK  +   L      +  +
Sbjct: 487 KQQHQEQQALQQSTTAKLREAQNDLEQVLRQIG--------DKDQKIQNLE----ALLQK 534

Query: 309 AGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGF--- 365
           + E   + E+E + L+  I+    E + L     +     ++  +L   L  + +     
Sbjct: 535 SKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQA 594

Query: 366 ---LGQWERAQREQAQTARD-LQELRGRADELCTMVERSAVSVASLRSELEGLGPLKPIL 421
              L    + Q+   + A+D +  L    +EL + +  S   V+ L  +++    L    
Sbjct: 595 QENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELL--- 651

Query: 422 EEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQ 481
                +   + +  DL  +LD       A+ A Q  Q     +   LD+    L D+ + 
Sbjct: 652 --LSAEAAKTAQRADLQNHLD------TAQNALQDKQQELNKITTQLDQVTAKLQDKQEH 703

Query: 482 RGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQDEALRAK 530
                    C +L   + E + + L+   + E L   ++  + ++L  K
Sbjct: 704 ---------CSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVK 743



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 34/146 (23%), Positives = 62/146 (42%), Gaps = 7/146 (4%)

Query: 127 ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRR------- 179
           AD+   L    + L   +  +  +  + ++V   +Q  Q  CS L  +L+  +       
Sbjct: 663 ADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLE 722

Query: 180 QEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQ 239
           Q+ EELEG   +L+ +  +V  S E A       +Q +  LE +   L +QL+ E     
Sbjct: 723 QKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVS 782

Query: 240 EAELQEPEEKQEPEEKQEPEEKQKPE 265
              L   ++ +  E  ++   KQ+ E
Sbjct: 783 STRLDLQKKSEALESIKQKLTKQEEE 808



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 6/117 (5%)

Query: 144  KDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSV 203
            K S+   KE ++++   + S+Q +       L++  +E ++L+G   +LK++  +  + +
Sbjct: 916  KKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQI 975

Query: 204  E--DAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQE--AELQEPEEKQEPEEKQ 256
            E    E+K  VL++    LE KL+    Q   E    +E  + LQ   EK +   KQ
Sbjct: 976  EALQGELKIAVLQKTE--LENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQ 1030



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 91/473 (19%), Positives = 165/473 (34%), Gaps = 100/473 (21%)

Query: 128 DITEILSGVNSGLVRAKDSITSLKEKTN--------------RVNQHVQSLQSECSVLSE 173
           ++T+    +   L++ +   T L+EK N              + +   Q LQS  S    
Sbjct: 299 ELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASET 358

Query: 174 NLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVL-------KQNSALLEEKLRY 226
           +L R   E  E      +LKE   +V    +  + +   L       +Q+   L+ ++  
Sbjct: 359 SLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQ 418

Query: 227 LQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPP 286
           L  +L +   +  EA  +  E++Q   EK   +E+Q  +  L  + L             
Sbjct: 419 LHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRL------------- 465

Query: 287 GSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEG 346
                                         E++L++  T   EL+ ++   T + HQE+ 
Sbjct: 466 ------------------------------EEQLKEKVTNSTELQHQLDK-TKQQHQEQQ 494

Query: 347 AVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSAVSVAS 406
           A+Q++                +   AQ +  Q  R + +   +   L  ++++S  +++ 
Sbjct: 495 ALQQST-------------TAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISL 541

Query: 407 LRSELEGL-----------GPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQ 455
           L  E E L             L  + E+     +   +  +   N   SH+        Q
Sbjct: 542 LEKEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQ 601

Query: 456 GSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKH---VRA 512
             Q     L+   DR L SL   V +              +K+ +L+ Q  AK    + A
Sbjct: 602 -VQEQKAHLRAAQDRVL-SLETSVNELN-----SQLNESKEKVSQLDIQIKAKTELLLSA 654

Query: 513 EALSSTLRLAQDEALRAKNLLLTDKMKPEEKMAT-LDHLHLKMCSLHDHLSNL 564
           EA  +  R      L      L DK +   K+ T LD +  K+    +H S L
Sbjct: 655 EAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQL 707



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 26/121 (21%), Positives = 57/121 (47%), Gaps = 6/121 (4%)

Query: 135 GVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLER----RRQEAEELEGYCI 190
           G  S L   +D +T L+++   +   ++  +     L + LE+    ++QEA+  +G   
Sbjct: 73  GGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKP-DGLVT 131

Query: 191 QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQD-ETPRRQEAELQEPEEK 249
                   + + +E+A+ +   +KQ   L E+K   L  ++ D ++   +E  L+E  E+
Sbjct: 132 DSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQ 191

Query: 250 Q 250
           +
Sbjct: 192 K 192



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 35/162 (21%), Positives = 66/162 (40%), Gaps = 11/162 (6%)

Query: 102  VEDLSGQLTLAGPPASPTLPWDPDDADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHV 161
            +E L G+L +A       L     +  + + L+     L   K+ I+ L+    +  +  
Sbjct: 975  IEALQGELKIA------VLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETF 1028

Query: 162  QSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLE 221
            + LQS+       L   RQ+ + +E      +E+       + +       LK   A LE
Sbjct: 1029 KQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLE 1088

Query: 222  EKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQK 263
            +     +QQLQ+         LQ+ ++++  +EK+   EK K
Sbjct: 1089 QDSAKKEQQLQERC-----KALQDIQKEKSLKEKELVNEKSK 1125



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 24/113 (21%), Positives = 56/113 (49%), Gaps = 13/113 (11%)

Query: 161  VQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALL 220
            +Q +Q E S+  + L   + +  E+E    + ++   K+   ++  ++++  +K+ + L 
Sbjct: 1105 LQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLES--IKEITNLK 1162

Query: 221  EEKLRYLQQQLQ-----------DETPRRQEAELQEPEEKQEPEEKQEPEEKQ 262
            + K   +QQ+L+            E  +R +  L++  +K+E E K+E  EK+
Sbjct: 1163 DAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKE 1215


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 35/117 (29%), Positives = 58/117 (49%), Gaps = 4/117 (3%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+  R  Q     Q E     E + R++++  E E    Q +E  W+    + D E K
Sbjct: 452 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ-EEKVWRQEEKMHDQEEK 510

Query: 210 TNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEKQ-EPEEKQEPEEKQK 263
               ++     EEK+R  ++++  Q+E  R QE  +QE EEK  E EEK + +EK +
Sbjct: 511 IREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR 567



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 39/152 (25%), Positives = 74/152 (48%), Gaps = 12/152 (7%)

Query: 128 DITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEG 187
           ++T+    ++  L R   +   LKEK  ++ + +Q ++SE S +  N++  +++ E  + 
Sbjct: 197 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK- 255

Query: 188 YCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPE 247
             + L +   +        E+++   K  + + E +L     Q Q+E   RQE ++QE E
Sbjct: 256 --LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE 313

Query: 248 EK-QEPEEK--------QEPEEKQKPEAGLSW 270
           EK QE EEK        +E EEK + +  + W
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 16/156 (10%)

Query: 126 DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHV--QSLQSECSVLSENLE----RRR 179
           +A + E L  V S     + ++  LK K  R    +  Q LQ+E   L + L+    + +
Sbjct: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 282

Query: 180 QEAEELEGYCI---QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETP 236
            + EE E +     Q +E  W+    +++ E K    ++     EEK+R      Q+E  
Sbjct: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE-----QEEKM 337

Query: 237 RRQEAELQEPEEKQEPEEKQ--EPEEKQKPEAGLSW 270
           RRQE  + E EEK   +E+   E EEK +    + W
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 33/119 (27%), Positives = 59/119 (49%), Gaps = 8/119 (6%)

Query: 151 KEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCW----KVTRSVE-- 204
           +EK  R  + +Q  + +     E +  + ++  E E    + +E  W    K+ R  E  
Sbjct: 299 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358

Query: 205 -DAEIKTNVLKQNSALLEEKLRYLQQQL-QDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            + E K   L++     EEK+R L++++ + E  R QE + QE E+ +E E++QE E K
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 29/137 (21%), Positives = 60/137 (43%), Gaps = 8/137 (5%)

Query: 142 RAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTR 201
           R ++ I   +EK     + ++  + +     E + R+ +   E E    + +E  W+   
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363

Query: 202 SVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEK------ 255
            +   E      ++    LEEK+   ++  + E  R++E +++E E++QE E K      
Sbjct: 364 KMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 423

Query: 256 --QEPEEKQKPEAGLSW 270
             +E EEK + +    W
Sbjct: 424 KIREQEEKIREQEKKMW 440



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 29/130 (22%), Positives = 59/130 (45%), Gaps = 19/130 (14%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+  ++ +  + ++ +  ++ E  E+  ++ E++     Q +E   +    + + E K
Sbjct: 525 IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM-----QEQEKMRRQEEKIREQEEK 579

Query: 210 TNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEK---------QEPEEKQEPEE 260
               K+     EEK+       Q+E  R QE  +QE EEK         ++ E+ QE EE
Sbjct: 580 IREQKEKIREQEEKIWE-----QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634

Query: 261 KQKPEAGLSW 270
           K + +    W
Sbjct: 635 KMRRQEEKMW 644



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 31/147 (21%), Positives = 66/147 (44%), Gaps = 19/147 (12%)

Query: 142 RAKDSITSLKEKTNRVNQHVQSLQSECSVLSENL---------ERRRQEAEELEGYCIQL 192
           R ++ +   +EK  R+ + +   + +   L E +         E +RQE E++     + 
Sbjct: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 412

Query: 193 KENC--WKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPR-------RQEAEL 243
           ++    W+    + + E K    ++     EEK+ + Q+++++E  R       RQE ++
Sbjct: 413 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI-HEQEKIREEEKRQEQEEMWRQEEKI 471

Query: 244 QEPEEKQEPEEKQEPEEKQKPEAGLSW 270
           +E EE    +EK   +EK + +    W
Sbjct: 472 REQEEIWRQKEKMHEQEKIRKQEEKVW 498



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 29/131 (22%), Positives = 64/131 (48%), Gaps = 17/131 (12%)

Query: 141 VRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVT 200
           +R ++ I   KEK +         Q +     E + R+ ++  + E    + +E  W+  
Sbjct: 471 IREQEEIWRQKEKMHE--------QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQE 522

Query: 201 RSVEDAEIKTNV----LKQNSALL---EEKLRYLQQQLQD-ETPRRQEAELQEPEEKQEP 252
             + + E K       +++   ++   EEK+   ++++Q+ E  RRQE +++E EEK   
Sbjct: 523 EKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIR- 581

Query: 253 EEKQEPEEKQK 263
           E+K++  E+++
Sbjct: 582 EQKEKIREQEE 592



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 23/112 (20%), Positives = 55/112 (49%), Gaps = 6/112 (5%)

Query: 159 QHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA 218
           Q  + ++ +   + E  E+ R++ E++     + +E  W+    + + E      ++   
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIR----EQEEKIWEQEEKIREQEEMMQEQEEKMW 616

Query: 219 LLEEKLRYLQQQLQD--ETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGL 268
             EEK+   ++++Q+  E  RRQE ++ E E +   +E++  E ++  EA +
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 39/145 (26%), Positives = 74/145 (51%), Gaps = 5/145 (3%)

Query: 128 DITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEG 187
           ++T+    ++  L R   +   LKEK  ++ + +Q ++SE S +  N++  +++ E  + 
Sbjct: 185 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAK- 243

Query: 188 YCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPE 247
             + L +   +        E+++   K  + + E +L     Q Q+E   RQE ++QE E
Sbjct: 244 --LLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQERE 301

Query: 248 EK-QEPEEK-QEPEEKQKPEAGLSW 270
           EK QE EEK +E EEK + +  + W
Sbjct: 302 EKIQEQEEKIREQEEKMRRQEEMMW 326



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 12/148 (8%)

Query: 126 DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHV--QSLQSECSVLSENLE----RRR 179
           +A + E L  V S     + ++  LK K  R    +  Q LQ+E   L + L+    + +
Sbjct: 211 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 270

Query: 180 QEAEELEGYCI---QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQL--QDE 234
            + EE E +     Q +E  W+    +++ E K    ++     EEK+R  ++ +  ++E
Sbjct: 271 AQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEE 330

Query: 235 TPRRQEAELQEPEEK-QEPEEKQEPEEK 261
             RRQE  + E EEK +E EEK   +EK
Sbjct: 331 KMRRQEEMMWEKEEKIRELEEKMHEQEK 358



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 10/114 (8%)

Query: 152 EKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTN 211
           E  NR+NQ  +          +  E + QE EE      +++E   K+ R  E    K  
Sbjct: 277 ELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEE------KIREQEEKMRRQEEMMWEKEE 330

Query: 212 VLKQNSALL---EEKLRYLQQQL-QDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
            +++   ++   EEK+R L++++ + E  R QE + QE E+ +E E++QE E K
Sbjct: 331 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 29/116 (25%), Positives = 54/116 (46%), Gaps = 7/116 (6%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEA--EELEGYCIQLKENCWKVTRSVEDAE 207
           ++E+  R  Q  +  + E  +  +  + R QE   +E E    + +E  W+    +++ E
Sbjct: 372 IREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431

Query: 208 IKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQK 263
            K    ++     E+K+R      Q+E  R QE  +QE EEK   +E +  E++ K
Sbjct: 432 EKMRRQEEKIREQEKKIRE-----QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 31/130 (23%), Positives = 60/130 (46%), Gaps = 12/130 (9%)

Query: 151 KEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKT 210
           +EK     + +Q  + +     E + R+ +   E E    + +E  W+    + + E K 
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353

Query: 211 NVLKQNSALLEEKLRYLQQQLQDETPRR-QEAELQEPEEK-QEPEEK--------QEPEE 260
           +  +Q     +E+ R  +++++++  R+ QEA++   EEK +E EEK        QE EE
Sbjct: 354 H--EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411

Query: 261 KQKPEAGLSW 270
           K   +    W
Sbjct: 412 KMGEQEEKMW 421



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 26/120 (21%), Positives = 63/120 (52%), Gaps = 8/120 (6%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+  ++ +  + ++ +  ++ E  E+  ++  ++     +++E   K+ R  E    +
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQ 500

Query: 210 TNVLKQNSALLEEKLRYLQQQLQDETPR--RQEAELQEPEEK-QEPEEK-QEPEEKQKPE 265
              +++     EEK+R  ++ +Q++  +   QE ++ E EEK QE EEK +  EEK + +
Sbjct: 501 EKKIREQ----EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQ 556



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 22/110 (20%), Positives = 56/110 (50%), Gaps = 4/110 (3%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+  ++ +    +  + + + E  E+ R++ E++     +++E   K+    E  + +
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 521

Query: 210 TNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEE--KQEPEEKQE 257
              + +    + E+   +Q+Q  +E  RRQE +++E E   +Q+ E+ QE
Sbjct: 522 EEKMWEQEEKMCEQEEKMQEQ--EEKMRRQEEKMREQEVRLRQQEEKMQE 569


>gi|31543392 peroxisome proliferator-activated receptor gamma,
           coactivator 1 beta [Homo sapiens]
          Length = 1023

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 35/100 (35%), Positives = 49/100 (49%), Gaps = 22/100 (22%)

Query: 224 LRYLQQQLQDETPR-----RQEAELQEPEEKQEPEEKQEPEE--KQKPEAGLSWNSLGPA 276
           LR L+ +++ E  R     +QE E +E EE++E EEK+E EE  +++P  GL W  LG  
Sbjct: 409 LRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEWGRKRPGRGLPWTKLGRK 468

Query: 277 ATSQGCP-----------GP----PGSPDKPSRPHGLVPA 301
             S  CP           GP       P  PS P G +P+
Sbjct: 469 LESSVCPVRRSRRLNPELGPWLTFADEPLVPSEPQGALPS 508


>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
          Length = 1476

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 97/425 (22%), Positives = 166/425 (39%), Gaps = 57/425 (13%)

Query: 150  LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
            L+ ++    + +Q L+SE     E  ER R+E E L+                   AE++
Sbjct: 835  LRAQSEAAEERMQVLESEGRQHLEEAERERREKEALQ-------------------AELE 875

Query: 210  TNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLS 269
              V++     L  +L +LQ++L+     RQE  L+E E +   +  Q  E++ + E   +
Sbjct: 876  KAVVRGKE--LGARLEHLQRELEQAALERQEF-LREKESQH--QRYQGLEQRLEAELQAA 930

Query: 270  WNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEE 329
              S   A             +      G  PA  G+GP+    P + E +  +L     E
Sbjct: 931  ATSKEEALMELKTRALQLEEELFQLRQG--PA--GLGPKKRAEPQLVETQNVRLI----E 982

Query: 330  LRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGR 389
            + R  + L A     +G +Q     LG L GR    L Q +RAQ   ++   +   L  +
Sbjct: 983  VERSNAMLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRAQEHSSRLQAEKSVLEIQ 1042

Query: 390  ADELCTMVERSAVSV-ASLRSELEGLGPLKPILEEFGRQFQNSRRGP-----------DL 437
              EL   +E     V A+ +S+ E  G  + +L +     Q  RR             DL
Sbjct: 1043 GQELHRKLEVLEEEVRAARQSQEETRGQQQALLRDHKALAQLQRRQEAELEGLLVRHRDL 1102

Query: 438  SMNL------DRSHQGNCARCASQGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSC 491
              N+       R  QG   +  +Q + +  + +  L +R    + D  +QRGL       
Sbjct: 1103 KANMRALELAHRELQGRHEQLQAQRASVEAQEVALLAERE-RLMQDGHRQRGLEEELRRL 1161

Query: 492  QRLHKK----ILELERQALAKHVRAEALSSTLRLAQDEALRAKNLLLTDKMKPEEKMATL 547
            Q  H +    + EL R+     ++ E      RLA+ E  RA+  + + +++   +   L
Sbjct: 1162 QSEHDRAQMLLAELSRE--RGELQGERGELRGRLARLELERAQLEMQSQQLRESNQQLDL 1219

Query: 548  DHLHL 552
                L
Sbjct: 1220 SACRL 1224



 Score = 32.7 bits (73), Expect = 0.96
 Identities = 51/232 (21%), Positives = 83/232 (35%), Gaps = 62/232 (26%)

Query: 140 LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQ-------- 191
           L  AK  +  L+++     + +   Q+E   L   + R RQEA+ L G   +        
Sbjct: 260 LANAKAQLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLRQEAQALSGQAKRAELYREEA 319

Query: 192 --LKENCWKVTR--------------------SVEDAEIKTNVLKQNSALLEEKL----- 224
             L+E   ++ R                     +E+  + + VL+ + ALLEE+L     
Sbjct: 320 EALRERAGRLPRLQEELRRCRERLQAAEAYKSQLEEERVLSGVLEASKALLEEQLEAARE 379

Query: 225 ---RYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQG 281
              R  + Q ++   R +  E     +    +  Q  EE  + E  L   SL P      
Sbjct: 380 RCARLHETQRENLLLRTRLGEAHAELDSLRHQVDQLAEENVELELELQ-RSLEP------ 432

Query: 282 CPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRRE 333
              PPGSP              G  P AG  P + ++  +     +  L RE
Sbjct: 433 ---PPGSP--------------GEAPLAGAAPSLQDEVREAEAGRLRTLERE 467


>gi|55769548 PHD finger protein 14 isoform 2 [Homo sapiens]
          Length = 888

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)

Query: 186 EGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA----LLEEKLRYLQQQLQDETPRRQEA 241
           EG C   +EN  +   + ED ++K   LK ++       E++L  ++++ ++E   R   
Sbjct: 55  EGSCSDSEENILEEELN-EDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRK 113

Query: 242 ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRP 295
           + ++ +EK++ +EK++  EK+K +A +S N    AA +     PP     PS P
Sbjct: 114 KKEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVP 167


>gi|55769550 PHD finger protein 14 isoform 1 [Homo sapiens]
          Length = 948

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 31/114 (27%), Positives = 59/114 (51%), Gaps = 5/114 (4%)

Query: 186 EGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSA----LLEEKLRYLQQQLQDETPRRQEA 241
           EG C   +EN  +   + ED ++K   LK ++       E++L  ++++ ++E   R   
Sbjct: 55  EGSCSDSEENILEEELN-EDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRK 113

Query: 242 ELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRP 295
           + ++ +EK++ +EK++  EK+K +A +S N    AA +     PP     PS P
Sbjct: 114 KKEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVP 167


>gi|226495417 coiled-coil domain containing 102A [Homo sapiens]
          Length = 550

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 115/534 (21%), Positives = 199/534 (37%), Gaps = 125/534 (23%)

Query: 56  HGVEPQMSHQPMHWCLNLKRSSACTNVSLLNLAAMEPTDSTGTDSTVEDLSGQLTLAGPP 115
           HG  P+++  P      L + S  T +   +   M P DS          SG  +   PP
Sbjct: 3   HGPSPRLAESPQ-----LSKGSLLTILGSPSPERMGPADSLPPTPP----SGTPSPGPPP 53

Query: 116 ASPTLP---------WDP-DDADITEI------LSGVNSGLVRAKDSITSLKEK------ 153
           A P  P         W+  ++  + E+       + +   + R  D   + +EK      
Sbjct: 54  ALPLPPAPALLADGDWESREELRLRELEEARARAAQMEKTMRRWSDCTANWREKWSKVRA 113

Query: 154 -TNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV--TRSVEDAEIKT 210
             NR  + V+ L+     L++ L   R+E +E +G C        ++   R V D     
Sbjct: 114 ERNRAREEVRQLRQRLDALTKELAGARRERQEAQGECEARGRELARLRGARGVADQ---- 169

Query: 211 NVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSW 270
               ++    E +   ++    +  P  QE EL E   K  PEE ++  E          
Sbjct: 170 ---TRDGPEPEAEREPVRDVGSERPPGSQELELVESLLKSMPEESEDCWE---------- 216

Query: 271 NSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEEL 330
                 A S G  GP GS  +  R        W       E    +E+E  KL T +   
Sbjct: 217 ------ARSLGAGGPRGSSGRQERSR----LPW-------EDTAATEEEASKL-TALRLR 258

Query: 331 RREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRA 390
             E   +  +  +++ A+   +        +++G L QW+    E ++T +++ +     
Sbjct: 259 LDESQKVLLKEREDKLALSRNIE-------KLEGELSQWKIKYEELSKTKQEMLK----- 306

Query: 391 DELCTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCA 450
            +L  + E     +  +  +LE         +E G +    R+  +L   ++R    N A
Sbjct: 307 -QLSILKEAHQDELGRMSEDLE---------DELGARSSMDRKMAELRGEMERLQAENAA 356

Query: 451 RCASQGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHV 510
               +  +L TE L   L+R                     ++L  ++ +LE +ALA+  
Sbjct: 357 EWGRR-ERLETEKLG--LER-------------------ENKKLRAQVGDLE-EALARRR 393

Query: 511 R--AEALSSTLRLAQDEALRAKNLLLTD--------KMKPEEKMATLDHLHLKM 554
           R  A AL   LR +Q  AL  KN  L D        K + +EK+A L H + ++
Sbjct: 394 RQTASALDCDLRASQ-AALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRV 446


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 92/446 (20%), Positives = 178/446 (39%), Gaps = 58/446 (13%)

Query: 151  KEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKT 210
            + K  +++  VQ L ++   +SE    R + AE+      +L+     V+  +E+AE K 
Sbjct: 1251 EHKRKKLDAQVQELHAK---VSEGDRLRVELAEKAS----KLQNELDNVSTLLEEAEKKG 1303

Query: 211  NVLKQNSALLEEKLRYLQQQLQDETPRRQEAEL-----QEPEEKQEPEEKQEPEEKQKPE 265
                +++A LE +L+  Q+ LQ+ET  RQ+  L     Q  EEK   +E+QE EE+ +  
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEET--RQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN 1361

Query: 266  AGLSWNSLGP--AATSQGCPGPPGSPDK-PSRPHGLVPAGWGMGPRAGEGPYV------- 315
                  +L    A T +      G+ +        L+     +  R  E           
Sbjct: 1362 LEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKT 1421

Query: 316  ---SEQELQKLFTGIEELRR-----------------EVSSLTARWHQE----EGAVQEA 351
                +QEL  L   ++  R+                 E  S++AR+ +E    E   +E 
Sbjct: 1422 KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK 1481

Query: 352  LRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADELCTMVERSAVSVASLRSEL 411
                  L   ++  L   E  +R+  Q   D+++L    D++   V     S  +L  ++
Sbjct: 1482 ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV 1541

Query: 412  EGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLSTESLQQLLDRA 471
            E +      LE+  +  ++++   +++M   ++      +   + ++     L + +   
Sbjct: 1542 EEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVREL 1601

Query: 472  LTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRLAQ-------- 523
               L DE KQR L  A      +  K LE + +A A   R E +    +L          
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEA-ANKARDEVIKQLRKLQAQMKDYQRE 1660

Query: 524  -DEALRAKNLLLTDKMKPEEKMATLD 548
             +EA  +++ +     + E+K+ +L+
Sbjct: 1661 LEEARASRDEIFAQSKESEKKLKSLE 1686



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 28/134 (20%), Positives = 66/134 (49%), Gaps = 7/134 (5%)

Query: 131 EILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQ---EAEELEG 187
           E L   +  L++ K+  T ++ +   + +  Q L  E ++L+E L+   +   EAEE+  
Sbjct: 852 EELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRA 911

Query: 188 YCIQLKENCWKVTRS----VEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAEL 243
                K+   ++       VE+ E +  +L+     ++  ++ L++QL +E   RQ+ +L
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQL 971

Query: 244 QEPEEKQEPEEKQE 257
           ++   + + ++ +E
Sbjct: 972 EKVTAEAKIKKMEE 985



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 68/360 (18%), Positives = 140/360 (38%), Gaps = 48/360 (13%)

Query: 155  NRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLK 214
            N   + V+ LQ++ + L E+ E  +    + E     L E    +   +ED    T   +
Sbjct: 1107 NNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166

Query: 215  QNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQE---PEEKQEPEEKQKPEAGLSWN 271
            +     E+++  L++ L++ET +  EA++Q+  ++      E  ++ E+ ++ +A L  N
Sbjct: 1167 ELRTKREQEVAELKKALEEET-KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKN 1225

Query: 272  SLGPAATSQ--GCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEE 329
              G    ++   C        K                        SE + +KL   ++E
Sbjct: 1226 KQGLETDNKELACEVKVLQQVKAE----------------------SEHKRKKLDAQVQE 1263

Query: 330  LRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGR 389
            L  +VS       + +    E       L   +D      E A+++  + A+D   L  +
Sbjct: 1264 LHAKVS-------EGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQ 1316

Query: 390  ADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNC 449
              +   +++       +L S +  L   K  L+E   + + +R+      NL++      
Sbjct: 1317 LQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARK------NLEK------ 1364

Query: 450  ARCASQGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKH 509
             +  +  SQL+    +   D      ++E K++ L  A    QRL +K L  ++    K+
Sbjct: 1365 -QVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKN 1423



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 80/420 (19%), Positives = 158/420 (37%), Gaps = 57/420 (13%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            L   K       E+ +R     +  +++   L+  LE   +  EE E    QL+ +   +
Sbjct: 1457 LAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDL 1516

Query: 200  TRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPE 259
              S +D     + L+++   LE+++  ++ QL++      E ELQ  E+ +   E     
Sbjct: 1517 MSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE-----LEDELQATEDAKLRLEVNMQA 1571

Query: 260  EKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQE 319
             K + E  L                   + D+ +                 E   +  ++
Sbjct: 1572 MKAQFERDLQ------------------TRDEQNE----------------EKKRLLIKQ 1597

Query: 320  LQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQT 379
            +++L   +E+ R++ +   A   + E  +++    +       D  + Q  + Q +    
Sbjct: 1598 VRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDY 1657

Query: 380  ARDLQELRGRADELCTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSM 439
             R+L+E R   DE+    + S   + SL +E+  L       E   R  +  R   +L+ 
Sbjct: 1658 QRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQER--DELAD 1715

Query: 440  NLDRSHQGNCA------RCASQGSQLSTE------SLQQLLDR-ALTSLVDEVKQRGLTP 486
             +  S  G  A      R  ++ +QL  E      +++ L DR   T+L  +     L  
Sbjct: 1716 EITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAA 1775

Query: 487  ACPSCQRLHKKILELERQALAKHVRAEALSSTLR---LAQDEALRAKNLLLTDKMKPEEK 543
               + Q+      +LERQ      + + L   ++    A   AL AK   L ++++ E K
Sbjct: 1776 ERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAK 1835



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 92/454 (20%), Positives = 172/454 (37%), Gaps = 65/454 (14%)

Query: 128  DITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEG 187
            ++ EIL  + S +   ++    L+ +  ++  H+Q L+       E L+      ++L+ 
Sbjct: 919  ELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLE-------EQLDEEEGARQKLQL 971

Query: 188  YCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPR---------R 238
              +  +    K+   +   E + +   +   L+E+++     QL +E  +         +
Sbjct: 972  EKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNK 1031

Query: 239  QEAELQEPEEKQEPEEK--QEPEEKQKPEAGLSWNSLGPAATSQGCPG--PPGSPDKPSR 294
            QE  + + EE+ + EEK  QE E+ ++   G + +     A  Q            K   
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1091

Query: 295  PHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRL 354
              G +  G            V  +   ++    E+   E +S      Q+    +E   L
Sbjct: 1092 LQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEAL 1151

Query: 355  LGGLGGRVDGFLGQWE-RAQREQ--AQTARDL-QELRGRADELCTMVERSAVSVASLRSE 410
               L   +D    Q E R +REQ  A+  + L +E +    ++  M +R A ++  L  +
Sbjct: 1152 KTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQ 1211

Query: 411  LEGLGPLKPILE--EFGRQFQNSRRGPDLSM-------------NLDRSHQGNCARCASQ 455
            LE     K  LE  + G +  N     ++ +              LD   Q   A+  S+
Sbjct: 1212 LEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAK-VSE 1270

Query: 456  GSQLSTE------SLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKH 509
            G +L  E       LQ  LD  +++L++E +++G+        +  K    LE Q     
Sbjct: 1271 GDRLRVELAEKASKLQNELDN-VSTLLEEAEKKGI--------KFAKDAASLESQ----- 1316

Query: 510  VRAEALSSTLRLAQDEALRAKNLLLTDKMKPEEK 543
                 L  T  L Q+E  +  NL    +   EEK
Sbjct: 1317 -----LQDTQELLQEETRQKLNLSSRIRQLEEEK 1345



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 24/127 (18%), Positives = 51/127 (40%), Gaps = 3/127 (2%)

Query: 161  VQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALL 220
            + +L+++   L E LE+  +E         + ++   ++   VED     +  K+     
Sbjct: 1816 ISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKA 1875

Query: 221  EEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSL---GPAA 277
              +++ L++QL++       A     + ++E ++  E  E    E     N L   GP +
Sbjct: 1876 NARMKQLKRQLEEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRRGGPIS 1935

Query: 278  TSQGCPG 284
             S    G
Sbjct: 1936 FSSSRSG 1942


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 31/116 (26%), Positives = 57/116 (49%), Gaps = 2/116 (1%)

Query: 150 LKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIK 209
           ++E+  R  Q     Q E     E + R++++  E E    + +E  W+    + D E K
Sbjct: 513 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK 572

Query: 210 TNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEKQEPEEKQEPEEKQK 263
               ++     EEK+R  ++++  Q+E  R QE   QE EEK   +E++  E+++K
Sbjct: 573 IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 38/163 (23%), Positives = 80/163 (49%), Gaps = 20/163 (12%)

Query: 128 DITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAE---- 183
           ++T+    ++  L R   +   LKEK  ++ + +Q ++SE S +  N++  +++ E    
Sbjct: 258 ELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKL 317

Query: 184 ---------ELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALL---EEKLRYLQQQL 231
                    E +    +L+    K+   VE+ E+   + +Q    +   EEK++  ++++
Sbjct: 318 LLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI 377

Query: 232 --QDETPRRQEAELQEPEEKQEPEEKQ--EPEEKQKPEAGLSW 270
             Q+E  R QE +++E EEK   +E+   E EEK + +  + W
Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 420



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 43/156 (27%), Positives = 71/156 (45%), Gaps = 16/156 (10%)

Query: 126 DADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHV--QSLQSECSVLSENLE----RRR 179
           +A + E L  V S     + ++  LK K  R    +  Q LQ+E   L + L+    + +
Sbjct: 284 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 343

Query: 180 QEAEELEGYCI---QLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETP 236
            + EE E +     Q +E  W+    +++ E K    ++     EEK+R      Q+E  
Sbjct: 344 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE-----QEEKM 398

Query: 237 RRQEAELQEPEEKQEPEEKQ--EPEEKQKPEAGLSW 270
           RRQE  + E EEK   +E+   E EEK + +  + W
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 31/119 (26%), Positives = 59/119 (49%), Gaps = 8/119 (6%)

Query: 151 KEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCW----KVTRSVEDA 206
           +EK  R  + +Q  + +     E +  + ++  E E    + +E  W    K+ R  E  
Sbjct: 360 EEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 419

Query: 207 EIKTNVLKQNSALL---EEKLRYLQQQL-QDETPRRQEAELQEPEEKQEPEEKQEPEEK 261
             K   +++   ++   EEK+R L++++ + E  R QE + QE E+ +E E++QE E K
Sbjct: 420 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 478



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 49/261 (18%), Positives = 103/261 (39%), Gaps = 22/261 (8%)

Query: 142 RAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTR 201
           R ++ I   +EK     + ++  + +     E + R+ +   E E    + +E  W+   
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424

Query: 202 SVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEK------ 255
            +   E      ++    LEEK+   ++  + E  R++E +++E E++QE E K      
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484

Query: 256 --QEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGP 313
             +E EEK + +    W         +         ++           W    +  E  
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEM--------WRQEEKIREQE 536

Query: 314 YVSEQELQKLFTGIEELRREVSSLTARWHQEEGA--VQEALRLLGGLGGRVDGFLGQWER 371
            +  Q+ +K+    E++R++   +   W QEE     +E +R       R +  + + E 
Sbjct: 537 EIWRQK-EKIHEQEEKIRKQEEKM---WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEE 592

Query: 372 AQREQAQTARDLQELRGRADE 392
             REQ +  R+ +E+    +E
Sbjct: 593 KIREQEEKIREQEEMTQEQEE 613



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 31/140 (22%), Positives = 61/140 (43%), Gaps = 11/140 (7%)

Query: 142 RAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTR 201
           R ++ +   +EK     + V   + +     E +  + ++  E E    + +E   +   
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620

Query: 202 SVEDAEIKTNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEK---------Q 250
            + + E K    ++     EEK+R  ++++  Q+E  R QE  +QE EEK         +
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 680

Query: 251 EPEEKQEPEEKQKPEAGLSW 270
           + E+ QE EEK + +    W
Sbjct: 681 QEEKMQEQEEKMRRQEEKMW 700



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 29/122 (23%), Positives = 59/122 (48%), Gaps = 4/122 (3%)

Query: 144 KDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVTRSV 203
           ++ I   +EK  R  + +   + +     E + R+ ++  E E    + +E   +     
Sbjct: 549 EEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMT 608

Query: 204 EDAEIKTNVLKQNSALLEEKLRYLQQQL--QDETPRRQEAELQEPEEK--QEPEEKQEPE 259
           ++ E K    ++     EEK++  ++++  Q+E  R QE +++E EEK  ++ E  QE E
Sbjct: 609 QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 668

Query: 260 EK 261
           EK
Sbjct: 669 EK 670



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 24/128 (18%), Positives = 64/128 (50%), Gaps = 4/128 (3%)

Query: 141 VRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKVT 200
           +R ++ +T  +E+  ++ +  + +  +   + E  E+ R++ E++     +++E   K+ 
Sbjct: 601 IREQEEMT--QEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 658

Query: 201 RSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEEKQEPEEKQEPEE 260
              E  + +   + +    + E+   +Q+Q  +E  RRQE ++ E E +   +E++  E 
Sbjct: 659 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ--EEKMRRQEEKMWEQEVRLRQQEEKMQEH 716

Query: 261 KQKPEAGL 268
           ++  EA +
Sbjct: 717 QEHLEAAI 724


>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
          Length = 555

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 96/367 (26%), Positives = 148/367 (40%), Gaps = 62/367 (16%)

Query: 236 PRRQEAELQEPEEKQEPEEK-QEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSR 294
           P   E+E +E EE+Q   +     +E+ +   GL+      AA  +G PG PG P +P +
Sbjct: 40  PGELESEPEEEEEEQAASQGGTAADEQAEAPKGLT---AAEAAGEEG-PGEPGRPAEP-Q 94

Query: 295 PHGLVPAGWG----MGPRAGEGPYVSE-----QELQKLFTGIEELRREVSSLTARWHQEE 345
           P    PA  G      P  G GP   E     +EL++   G +E+R + S    R  +EE
Sbjct: 95  PEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEELEQAAEG-KEVRFQASLPLTRIDEEE 153

Query: 346 GAVQEALRLLGGLGGRVDGFLGQWERAQREQAQT---------ARDLQE---LRGR--AD 391
            A             RV+G     E  QR+ A++         A+  +E   L GR   +
Sbjct: 154 AAAAPEAET-----ERVEGEEEDKEETQRDGAESKERDGEGRPAKSQEEGKRLYGRDEFE 208

Query: 392 ELCTMVERSAVSVASLRSELEGLGPLKPILEEFGR-QFQNSRRGPDLSMNLDRSHQGNCA 450
           +L    E   +    LRS+L  L   + +L E  R Q  N      +   L R      A
Sbjct: 209 DLEWSEEVQKLQEQQLRSDL--LDQYRSLLVERNRSQRYNLYLQHKIFEALRRKKGLEAA 266

Query: 451 RCASQGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELER------- 503
             A +G++      +Q   R L  L +  KQ+         Q  H+++ +L+R       
Sbjct: 267 EVADRGAEAEAPEKEQAYLRHLGMLEELKKQQ-----ADDLQWYHQELGQLKRQCQEKLT 321

Query: 504 ---------QALAKHVRAEALSS-TLRLAQDEALRAKNLL--LTDKMKPEEKMATLDHLH 551
                    QAL K V  +A+ S  +R  +  ALR    +  L DK + E     L+++ 
Sbjct: 322 RVEKEWRRFQALKKQVVMQAMGSCRMRGGRQAALREVEQIQALEDKKEKEMSAVRLENIQ 381

Query: 552 LKMCSLH 558
           LK   +H
Sbjct: 382 LKQSLVH 388


>gi|122937219 F-box protein 41 [Homo sapiens]
          Length = 936

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 79/328 (24%), Positives = 124/328 (37%), Gaps = 37/328 (11%)

Query: 116 ASPTLPWDPDDADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQS----LQSECSVL 171
           ASP  P  P D    E L+ +    +   +    L+  +  V Q +      LQ+E    
Sbjct: 247 ASPASP-SPADVAYEEGLARLKIRALEKLEVDRRLERLSEEVEQKIAGQVGRLQAELERK 305

Query: 172 SENLERRRQEAEELEGYCIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQ- 230
           +  LE  RQE+  L     +L+E   +++R V+ +      LKQ+    E++L   QQ+ 
Sbjct: 306 AAELETARQESARLGREKEELEERASELSRQVDVSVELLASLKQDLVHKEQELSRKQQEV 365

Query: 231 ------LQDETPRRQEAELQEPEEKQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPG 284
                 L++   R   A+L+  +  +E  E+ +  E+Q      S  S   A+  +G  G
Sbjct: 366 VQIDQFLKETAAREASAKLRLQQFIEELLERADRAERQLQVISSSCGSTPSASLGRGGGG 425

Query: 285 PPGSPDK------------PSRPHGLVPAGWGMGPRAGEGPYVSEQELQKLFTGIEELRR 332
               P+             P+ P+    +  G  P  G    V            + L  
Sbjct: 426 GGAGPNARGPGRMREHHVGPAVPNTYAVSRHGSSPSTGASSRVPAASQSSGCYDSDSLEL 485

Query: 333 EVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQ--REQAQTARDLQELRGRA 390
                      EEGA +++    GGLG R     G  ER+Q  R      + +Q  + R 
Sbjct: 486 P--------RPEEGAPEDSGP--GGLGTRAQAANGGSERSQPPRSSGLRRQAIQNWQRRP 535

Query: 391 DELCTMVERSAVS-VASLRSELEGLGPL 417
               T  E   VS V S  +E E  GPL
Sbjct: 536 RRHSTEGEEGDVSDVGSRTTESEAEGPL 563



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 50/198 (25%), Positives = 88/198 (44%), Gaps = 25/198 (12%)

Query: 276 AATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYVSEQE-LQKL-FTGIEELRRE 333
           +  S  C  PP  P       G  P      P +     V+ +E L +L    +E+L  E
Sbjct: 223 SVASSACSTPPPGPGP-----GPCPGPASASPASPSPADVAYEEGLARLKIRALEKL--E 275

Query: 334 VSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTARDLQELRGRADEL 393
           V     R  +E    Q+    +G L   ++    + E A++E A+  R+ +EL  RA EL
Sbjct: 276 VDRRLERLSEE--VEQKIAGQVGRLQAELERKAAELETARQESARLGREKEELEERASEL 333

Query: 394 CTMVERSAVSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCA 453
              V+ S   +ASL+ +L              ++ + SR+  ++ + +D+  +   AR A
Sbjct: 334 SRQVDVSVELLASLKQDL------------VHKEQELSRKQQEV-VQIDQFLKETAAREA 380

Query: 454 SQGSQLSTESLQQLLDRA 471
           S   +L  + +++LL+RA
Sbjct: 381 SAKLRLQ-QFIEELLERA 397


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 104/510 (20%), Positives = 198/510 (38%), Gaps = 91/510 (17%)

Query: 140  LVRAKDSITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGYCIQLKENCWKV 199
            L RA +     +E+  R N+   +L++E   L  + +   +   ELE  C   ++    +
Sbjct: 1513 LTRALEEEQEAREELERQNR---ALRAELEALLSSKDDVGKSVHELERACRVAEQAANDL 1569

Query: 200  TRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEA----ELQEPEEKQEPEEK 255
               V + E +    +     LE  ++ L+ Q + +   R EA      Q  ++ ++ E +
Sbjct: 1570 RAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVE 1629

Query: 256  QEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGLVPAGWGMGPRAGEGPYV 315
            ++ E KQ+  A  +   L                       G +         AG+G   
Sbjct: 1630 RDEERKQRTLAVAARKKL----------------------EGELEELKAQMASAGQGKEE 1667

Query: 316  SEQELQKLFTGIEELRREVSSLTARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQRE 375
            + ++L+K+   ++EL REV        +     +E+ + L GL   V        R Q E
Sbjct: 1668 AVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEV-------LRLQEE 1720

Query: 376  QAQTARDLQELRGRADELCTMVERSAVSVASL---RSELEG-LGPLKPILEE-------- 423
             A + R  ++ +   DE+   V    +S A++   + +LEG LG L+  LEE        
Sbjct: 1721 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELL 1780

Query: 424  -----------------------FGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLS 460
                                   F  + ++ R+  +  +   R   G     A    +++
Sbjct: 1781 NDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMT 1840

Query: 461  TESLQQLLDRALTSLVDEVKQRGLTPAC--PSCQRLHKKILELE---------RQALAK- 508
              +L+  L +A   L  E ++R L+      + +RL + +L++E         R  L K 
Sbjct: 1841 IAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKG 1900

Query: 509  HVRAEALSSTLRLAQDEALRAKNLLLTDKMKPEEKMATLDHLHLKMCSLHDHLSNLPLEG 568
            ++R + L   L  A++EA RA+      + + E+   + + ++ ++ +L + L   PL  
Sbjct: 1901 NLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPLTF 1960

Query: 569  STGTM--------GGGSSAGTPPKQGGSAP 590
            +T T+        G  S       Q GS P
Sbjct: 1961 TTRTVRQVFRLEEGVASDEEAEEAQPGSGP 1990



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 94/442 (21%), Positives = 161/442 (36%), Gaps = 70/442 (15%)

Query: 136  VNSGLVRAKDS-------ITSLKEKTNRVNQHVQSLQSECSVLSENLERRRQEAEELEGY 188
            + + L RA+D        + SL+E    + +  + L+SE    ++  ++RR   EELE  
Sbjct: 1117 LQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEAL 1176

Query: 189  CIQLKENCWKVTRSVEDAEIKTNVLKQNSALLEEKLRYLQQQLQDETPRRQEAELQEPEE 248
              +L++         E    +   + +    LEE+ R  +  +Q+   R  +A  +  E+
Sbjct: 1177 RGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQ 1236

Query: 249  KQEPEEKQEPEEKQKPEAGLSWNSLGPAATSQGCPGPPGSPDKPSRPHGL--VPAGWGMG 306
             ++    +   EK +       + L    +S       G   +      L  V    G G
Sbjct: 1237 LEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDG 1296

Query: 307  PRA----GEGPYVSEQELQKLFTGIEE-------LRREVSSLTARWHQEEGAVQEALRLL 355
             RA     E    ++ EL+ +   + E       L +E+SS  A+ H  +  +QE  R  
Sbjct: 1297 ERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK 1356

Query: 356  GGLGGRVDGFLGQ--------------WERAQREQAQTARDLQELRGRADELCTMVERSA 401
              LG RV     +               ERA RE       L E R R +E    +E   
Sbjct: 1357 LALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGE 1416

Query: 402  VSVASLRSELEGLGPLKPILEEFGRQFQNSRRGPDLSMNLDRSHQGNCARCASQGSQLST 461
             +      E E L                ++R  + +  +DR  +G              
Sbjct: 1417 EARRRAAREAEAL----------------TQRLAEKTETVDRLERGR------------- 1447

Query: 462  ESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTLRL 521
              LQQ LD A    +D  +QR L       QR   ++L  E+ A+ + V     +     
Sbjct: 1448 RRLQQELDDA---TMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE---- 1500

Query: 522  AQDEALRAKNLLLTDKMKPEEK 543
            A+     A+ L LT  ++ E++
Sbjct: 1501 AEGREREARALSLTRALEEEQE 1522



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 101/467 (21%), Positives = 183/467 (39%), Gaps = 63/467 (13%)

Query: 127  ADITEILSGVNSGLVRAKDSITSLKEKTNRVNQHVQSLQS-------ECSVLSENLERRR 179
            A+  E +  +N   ++ + +I  ++++  +  +  Q L+        E S L E +  ++
Sbjct: 1041 AEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQ 1100

Query: 180  QEAEELEGYCIQLKENCWKVTRSVED-----AEIKTNVLKQNSALLEEKLRYLQQQLQDE 234
            Q AEEL     + +E         ED     A++  ++ +  +AL E      Q+ L+ E
Sbjct: 1101 QRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAE-----AQEDLESE 1155

Query: 235  TPRRQEAELQEPEEKQEPE--------------EKQEPEEKQKPEAGLSWNSLGPAATSQ 280
               R +AE Q  +  +E E               +QE   K++ E      +L       
Sbjct: 1156 RVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIH 1215

Query: 281  GCPGPPGSPDKPSRPHGLV---PAGWGMGPRAGEGPYVSEQELQKLFTGIEELRREVSSL 337
                   +  +  + HG      A      R G+G +  E+    L   + ELR E+SSL
Sbjct: 1216 -----EAAVQELRQRHGQALGELAEQLEQARRGKGAW--EKTRLALEAEVSELRAELSSL 1268

Query: 338  -TARWHQEEGAVQEALRLLGGLGGRVDGFLGQWERAQREQAQTAR----DLQELRGRADE 392
             TAR   E+   +  L+L       V G  G  ERA+ E A+  +    +L+ + G  +E
Sbjct: 1269 QTARQEGEQRRRRLELQL-----QEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1323

Query: 393  LCTMVERSAVSVASLRSELEGLGPL-------KPILEEFGRQFQNSRRGPDLSMNLDRSH 445
              +   R +  ++S  ++L     L       K  L    R  +    G    +  + + 
Sbjct: 1324 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAA 1383

Query: 446  QGNCAR-CASQGSQLSTESLQQLLDRALTSLVDEVKQRGLTPACPSCQRLHKKILELER- 503
            +    R   +  +QLS    +Q  +       +E ++R    A    QRL +K   ++R 
Sbjct: 1384 RERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRL 1443

Query: 504  QALAKHVRAEALSSTLRLAQDEALRA---KNLLLTDKMKPEEKMATL 547
            +   + ++ E   +T+ L Q   L +   K     D++  EEK A L
Sbjct: 1444 ERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 49/204 (24%), Positives = 90/204 (44%), Gaps = 47/204 (23%)

Query: 370  ERAQREQAQTARDLQELRGRA-----------------DELCTMVERSAVSVASLRSELE 412
            ++ Q  Q Q+AR++ EL+GR                   ELC   E +   +A+ + ELE
Sbjct: 887  QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELE 946

Query: 413  -GLGPLKPIL---EEFGRQFQNSRRG-----PDLSMNLDRSHQGNCARCASQGSQLSTES 463
              +  L+  +   EE  RQ Q  ++       +L  +L+ + +G  AR   Q  +++TE+
Sbjct: 947  LVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLE-AEEG--ARQKLQLEKVTTEA 1003

Query: 464  LQQLLDRALTSLVDE----VKQRGLTPACPSCQRLHKKILELERQALAKHVRAEALSSTL 519
              +  +  L  L D+     K+R L         L  ++ E   QA  +  + ++L+  L
Sbjct: 1004 KMKKFEEDLLLLEDQNSKLSKERKL---------LEDRLAEFSSQAAEEEEKVKSLNK-L 1053

Query: 520  RLAQDEALRAKNLLLTDKMKPEEK 543
            RL  +  +      + D+++ EEK
Sbjct: 1054 RLKYEATIAD----MEDRLRKEEK 1073


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,588,034
Number of Sequences: 37866
Number of extensions: 1381518
Number of successful extensions: 19388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 337
Number of HSP's successfully gapped in prelim test: 789
Number of HSP's that attempted gapping in prelim test: 11767
Number of HSP's gapped (non-prelim): 5702
length of query: 592
length of database: 18,247,518
effective HSP length: 108
effective length of query: 484
effective length of database: 14,157,990
effective search space: 6852467160
effective search space used: 6852467160
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.