BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens] (297 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens] 609 e-175 gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] 582 e-166 gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 327 1e-89 gi|4557489 cone-rod homeobox protein [Homo sapiens] 259 3e-69 gi|61969666 arginine-fifty homeobox [Homo sapiens] 103 2e-22 gi|46249382 paired-like homeobox 2a [Homo sapiens] 100 2e-21 gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 96 5e-20 gi|12707580 paired-like homeobox 2b [Homo sapiens] 95 6e-20 gi|189083681 paired box gene 6 isoform a [Homo sapiens] 93 3e-19 gi|4580424 paired box gene 6 isoform b [Homo sapiens] 93 3e-19 gi|4505615 paired box gene 6 isoform a [Homo sapiens] 93 3e-19 gi|7706659 paired related homeobox 2 [Homo sapiens] 92 4e-19 gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 91 1e-18 gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 91 1e-18 gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 91 2e-18 gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens] 90 2e-18 gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] 90 2e-18 gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 90 2e-18 gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 90 2e-18 gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 90 2e-18 gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 90 2e-18 gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 90 3e-18 gi|14149760 orthopedia homeobox [Homo sapiens] 90 3e-18 gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 89 5e-18 gi|87044888 short stature homeobox 2 isoform b [Homo sapiens] 89 5e-18 gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 89 6e-18 gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 88 1e-17 gi|24497589 aristaless related homeobox [Homo sapiens] 87 1e-17 gi|4826912 paired-like homeodomain 3 [Homo sapiens] 87 2e-17 gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 86 3e-17 >gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens] Length = 297 Score = 609 bits (1571), Expect = e-175 Identities = 297/297 (100%), Positives = 297/297 (100%) Query: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV Sbjct: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60 Query: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK Sbjct: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120 Query: 121 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 180 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ Sbjct: 121 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 180 Query: 181 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 240 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN Sbjct: 181 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 240 Query: 241 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 297 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL Sbjct: 241 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 297 >gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] Length = 289 Score = 582 bits (1500), Expect = e-166 Identities = 289/297 (97%), Positives = 289/297 (97%), Gaps = 8/297 (2%) Query: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYP ATPRKQRRERTTFTRAQLDV Sbjct: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYP--------ATPRKQRRERTTFTRAQLDV 52 Query: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK Sbjct: 53 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 112 Query: 121 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 180 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ Sbjct: 113 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 172 Query: 181 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 240 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN Sbjct: 173 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 232 Query: 241 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 297 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL Sbjct: 233 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 289 >gi|20070107 orthodenticle homeobox 1 [Homo sapiens] Length = 354 Score = 327 bits (837), Expect = 1e-89 Identities = 208/371 (56%), Positives = 230/371 (61%), Gaps = 91/371 (24%) Query: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60 MMSYLKQPPY +NGL L MDLLHPSVGYP ATPRKQRRERTTFTR+QLDV Sbjct: 1 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYP--------ATPRKQRRERTTFTRSQLDV 52 Query: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCR QQQQ+G K RPAK Sbjct: 53 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCR---QQQQSGSGTKSRPAK 109 Query: 121 KKTSPAREVSSESGTSGQFTPP---SSTSVPTIASSS----------------------- 154 KK+SP RE SS S +SGQFTPP SS S + ASSS Sbjct: 110 KKSSPVRE-SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSL 168 Query: 155 ---APVSIWSPASISPLSDPLSTS----------SSCMQR-----------SYPMTYTQA 190 A SIWSPASISP S P S S +SCMQR SYPM+Y Q Sbjct: 169 STPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQG 228 Query: 191 SGYSQGY-AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPAS--- 245 Y QGY S+SYFGG+DC SYL PMH H P LSPM +++ H + P + Sbjct: 229 GSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHP---HQLSPMAPSSMAGHHHHHPHAHHP 285 Query: 246 LST-------------QGYGASSLGFNSTTDCLDYKD-----QTASWKLNFNA-DCLDYK 286 LS QGYG S L FNS DCLDYK+ +++WKLNFN+ DCLDYK Sbjct: 286 LSQSSGHHHHHHHHHHQGYGGSGLAFNS-ADCLDYKEPGAAAASSAWKLNFNSPDCLDYK 344 Query: 287 DQTSSWKFQVL 297 DQ +SW+FQVL Sbjct: 345 DQ-ASWRFQVL 354 >gi|4557489 cone-rod homeobox protein [Homo sapiens] Length = 299 Score = 259 bits (661), Expect = 3e-69 Identities = 158/317 (49%), Positives = 197/317 (62%), Gaps = 38/317 (11%) Query: 1 MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLD 59 MM+Y+ P Y+VN L+L+ +DL+H +V YP + PRKQRRERTTFTR+QL+ Sbjct: 1 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYP--------SAPRKQRRERTTFTRSQLE 52 Query: 60 VLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQN 114 LEALFAKT+YPD++ REEVALKINLPESRVQVWFKNRRAKCRQQ QQQQ GGQ Sbjct: 53 ELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQA 112 Query: 115 KVRPAKKKTSPAREVSSE-----SGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLS 169 K RPAK+K + S++ G S ++PP + ++ A VSIWSPAS SPL Sbjct: 113 KARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLP 172 Query: 170 DP-----LSTSSSCMQRSYPMTYTQASGY---SQGYAGSTSYFGGMDCGSYLTPMHHQLP 221 + +++ S Y MTY AS + Y +SYF G+D YL+PM QL Sbjct: 173 EAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLG 230 Query: 222 GPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFN-A 280 GP LSP+ +V L QSP SLS Q YGA S D L++KD T +WK +N Sbjct: 231 GP--ALSPLSGPSVGPSLAQSPTSLSGQSYGA-----YSPVDSLEFKDPTGTWKFTYNPM 283 Query: 281 DCLDYKDQTSSWKFQVL 297 D LDYKDQ S+WKFQ+L Sbjct: 284 DPLDYKDQ-SAWKFQIL 299 >gi|61969666 arginine-fifty homeobox [Homo sapiens] Length = 315 Score = 103 bits (256), Expect = 2e-22 Identities = 93/286 (32%), Positives = 140/286 (48%), Gaps = 37/286 (12%) Query: 17 LTTSGMDLLHPSVGYPGPW-----ASCPAATP--RKQRRERTTFTRAQLDVLEALFAKTR 69 L SG + S+ PG AS AAT R++ +ERT+FT Q + LEALF++T Sbjct: 42 LECSGTVSAYCSLNLPGSTDPPTSASRVAATTAIRRRHKERTSFTHQQYEELEALFSQTM 101 Query: 70 YPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKK--TSPAR 127 +PD ++E++AL+++LPES V+VWF+NRR K ++QQQQQ +N++ P+KK TSP Sbjct: 102 FPDRNLQEKLALRLDLPESTVKVWFRNRRFKLKKQQQQQSAKQRNQILPSKKNVPTSPRT 161 Query: 128 EVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ------- 180 S + F+P S ++ S S W+ S S STS MQ Sbjct: 162 SPSPYA-----FSPVISDFYSSLPSQPLDPSNWAWNSTFTES---STSDFQMQDTQWERL 213 Query: 181 -RSYPMTYTQASG-------YSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGT 232 S P Y+ A Y+ S YL+P +Q+ G G++LS Sbjct: 214 VASVPALYSDAYDIFQIIELYNLPDENEISSSSFHCLYQYLSPTKYQVGGQGSSLSIFAG 273 Query: 233 NAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNF 278 AV Q+ ++++Q + A SL TD L+++ + L F Sbjct: 274 PAVGLSPAQTWPNMTSQAFEAYSL-----TDSLEFQKTSNMVDLGF 314 >gi|46249382 paired-like homeobox 2a [Homo sapiens] Length = 284 Score = 100 bits (248), Expect = 2e-21 Identities = 65/142 (45%), Positives = 83/142 (58%), Gaps = 15/142 (10%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTFT AQL LE +FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+ Sbjct: 88 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 147 Query: 104 QQQQQQNGGQNKVRPAKK---KTSPAREVSSESGTSGQFTPPSSTSV----------PTI 150 Q++ G AKK + S + S ES S TP S+ S+ P + Sbjct: 148 QERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSP--TPDSTASLPPPPAPGLASPRL 205 Query: 151 ASSSAPVSIWSPASISPLSDPL 172 + S PV++ S P PL Sbjct: 206 SPSPLPVALGSGPGPGPGPQPL 227 >gi|122937484 dorsal root ganglia homeobox [Homo sapiens] Length = 268 Score = 95.5 bits (236), Expect = 5e-20 Identities = 48/89 (53%), Positives = 63/89 (70%), Gaps = 1/89 (1%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTFT QL+ LEA+FA+T YPD+F REE+A+KINL E+RVQVWF+NRRAK R+ Sbjct: 36 RKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRK 95 Query: 104 QQQQQQNGGQNKVRPAKKKT-SPAREVSS 131 ++ + P + T P R ++S Sbjct: 96 TERGASDQEPGAKEPMAEVTPPPVRNINS 124 >gi|12707580 paired-like homeobox 2b [Homo sapiens] Length = 314 Score = 95.1 bits (235), Expect = 6e-20 Identities = 55/106 (51%), Positives = 70/106 (66%), Gaps = 4/106 (3%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTFT AQL LE +FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+ Sbjct: 96 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 155 Query: 104 QQQ-QQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVP 148 Q++ K + KK+ +R+ S+ S T P ST P Sbjct: 156 QERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKS---TDPDSTGGP 198 >gi|189083681 paired box gene 6 isoform a [Homo sapiens] Length = 422 Score = 92.8 bits (229), Expect = 3e-19 Identities = 62/186 (33%), Positives = 91/186 (48%), Gaps = 27/186 (14%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RK +R RT+FT+ Q++ LE F +T YPD+F RE +A KI+LPE+R+QVWF NRRAK R+ Sbjct: 208 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 267 Query: 104 QQQQQQNGGQNKVRPAKKKTS-----------PAREVSSESGTSGQFTPPSSTSVPTIAS 152 +++ + Q P+ S P S TSG + T++ S Sbjct: 268 EEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYS 327 Query: 153 SSAPVSIWSPASISPLSDP-----------LSTSSSCMQRSY-----PMTYTQASGYSQG 196 + P+ ++ A+ P+ P L TS S RSY P T + G Sbjct: 328 ALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG 387 Query: 197 YAGSTS 202 +G+TS Sbjct: 388 TSGTTS 393 >gi|4580424 paired box gene 6 isoform b [Homo sapiens] Length = 436 Score = 92.8 bits (229), Expect = 3e-19 Identities = 62/186 (33%), Positives = 91/186 (48%), Gaps = 27/186 (14%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RK +R RT+FT+ Q++ LE F +T YPD+F RE +A KI+LPE+R+QVWF NRRAK R+ Sbjct: 222 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 281 Query: 104 QQQQQQNGGQNKVRPAKKKTS-----------PAREVSSESGTSGQFTPPSSTSVPTIAS 152 +++ + Q P+ S P S TSG + T++ S Sbjct: 282 EEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYS 341 Query: 153 SSAPVSIWSPASISPLSDP-----------LSTSSSCMQRSY-----PMTYTQASGYSQG 196 + P+ ++ A+ P+ P L TS S RSY P T + G Sbjct: 342 ALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG 401 Query: 197 YAGSTS 202 +G+TS Sbjct: 402 TSGTTS 407 >gi|4505615 paired box gene 6 isoform a [Homo sapiens] Length = 422 Score = 92.8 bits (229), Expect = 3e-19 Identities = 62/186 (33%), Positives = 91/186 (48%), Gaps = 27/186 (14%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RK +R RT+FT+ Q++ LE F +T YPD+F RE +A KI+LPE+R+QVWF NRRAK R+ Sbjct: 208 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 267 Query: 104 QQQQQQNGGQNKVRPAKKKTS-----------PAREVSSESGTSGQFTPPSSTSVPTIAS 152 +++ + Q P+ S P S TSG + T++ S Sbjct: 268 EEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYS 327 Query: 153 SSAPVSIWSPASISPLSDP-----------LSTSSSCMQRSY-----PMTYTQASGYSQG 196 + P+ ++ A+ P+ P L TS S RSY P T + G Sbjct: 328 ALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG 387 Query: 197 YAGSTS 202 +G+TS Sbjct: 388 TSGTTS 393 >gi|7706659 paired related homeobox 2 [Homo sapiens] Length = 253 Score = 92.4 bits (228), Expect = 4e-19 Identities = 54/151 (35%), Positives = 79/151 (52%), Gaps = 14/151 (9%) Query: 32 PGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQ 91 P P A +KQRR RTTF +QL LE +F +T YPD F+REE+A ++NL E+RVQ Sbjct: 90 PSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQ 149 Query: 92 VWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVP--- 148 VWF+NRRAK R+ + + A + S + S E+ P + P Sbjct: 150 VWFQNRRAKFRRNE---------RAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYL 200 Query: 149 --TIASSSAPVSIWSPASISPLSDPLSTSSS 177 T +S + V +SP S P + ++ ++S Sbjct: 201 SWTASSPYSTVPPYSPGSSGPATPGVNMANS 231 >gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo sapiens] Length = 382 Score = 90.9 bits (224), Expect = 1e-18 Identities = 57/141 (40%), Positives = 70/141 (49%), Gaps = 16/141 (11%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ NLPE+RVQVWFKNRRAK R+ Sbjct: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128 Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163 +Q+ Q K++ +E G P T + T P + P Sbjct: 129 KQRSLQ----------KEQLQKQKEAEGSHGEGKAEAPTPDTQLDT----EQPPRL--PG 172 Query: 164 SISPLSDPLSTSSSCMQRSYP 184 S P LS S S P Sbjct: 173 SDPPAELHLSLSEQSASESAP 193 >gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo sapiens] Length = 377 Score = 90.9 bits (224), Expect = 1e-18 Identities = 57/141 (40%), Positives = 70/141 (49%), Gaps = 16/141 (11%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ NLPE+RVQVWFKNRRAK R+ Sbjct: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123 Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163 +Q+ Q K++ +E G P T + T P + P Sbjct: 124 KQRSLQ----------KEQLQKQKEAEGSHGEGKAEAPTPDTQLDT----EQPPRL--PG 167 Query: 164 SISPLSDPLSTSSSCMQRSYP 184 S P LS S S P Sbjct: 168 SDPPAELHLSLSEQSASESAP 188 >gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] Length = 407 Score = 90.5 bits (223), Expect = 2e-18 Identities = 77/226 (34%), Positives = 105/226 (46%), Gaps = 45/226 (19%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+ Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276 Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163 Q Q N + P G F P T++PT+ + + + P Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315 Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLT 214 SI +SDP ST S+ Q + P +S Y ST + S++ Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYC---LPSTRHGFSSYTDSFVP 372 Query: 215 PMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNS 260 P GP ++P N ++ Q P +S+Q SLGF S Sbjct: 373 P-----SGPSNPMNPTIGNGLSP---QVPFIISSQ----ISLGFKS 406 >gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens] Length = 225 Score = 90.1 bits (222), Expect = 2e-18 Identities = 42/70 (60%), Positives = 52/70 (74%) Query: 42 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 101 T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC Sbjct: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172 Query: 102 RQQQQQQQNG 111 R+Q+ Q G Sbjct: 173 RKQENQMHKG 182 >gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] Length = 292 Score = 90.1 bits (222), Expect = 2e-18 Identities = 42/70 (60%), Positives = 52/70 (74%) Query: 42 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 101 T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC Sbjct: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172 Query: 102 RQQQQQQQNG 111 R+Q+ Q G Sbjct: 173 RKQENQMHKG 182 >gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] Length = 483 Score = 90.1 bits (222), Expect = 2e-18 Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+ Sbjct: 216 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 275 Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163 Q Q N + P G F P T++PT+ + + + P Sbjct: 276 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 314 Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209 SI +SDP ST S+ Q + P +S Y G++ T F + Sbjct: 315 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 372 Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 238 PM+ P G LSP +T+H Sbjct: 373 SGPSNPMN---PTIGNGLSPQVMGLLTNH 398 >gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] Length = 505 Score = 90.1 bits (222), Expect = 2e-18 Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+ Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276 Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163 Q Q N + P G F P T++PT+ + + + P Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315 Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209 SI +SDP ST S+ Q + P +S Y G++ T F + Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373 Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 238 PM+ P G LSP +T+H Sbjct: 374 SGPSNPMN---PTIGNGLSPQVMGLLTNH 399 >gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] Length = 484 Score = 90.1 bits (222), Expect = 2e-18 Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+ Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276 Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163 Q Q N + P G F P T++PT+ + + + P Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315 Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209 SI +SDP ST S+ Q + P +S Y G++ T F + Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373 Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 238 PM+ P G LSP +T+H Sbjct: 374 SGPSNPMN---PTIGNGLSPQVMGLLTNH 399 >gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] Length = 479 Score = 90.1 bits (222), Expect = 2e-18 Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+ Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276 Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163 Q Q N + P G F P T++PT+ + + + P Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315 Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209 SI +SDP ST S+ Q + P +S Y G++ T F + Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373 Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 238 PM+ P G LSP +T+H Sbjct: 374 SGPSNPMN---PTIGNGLSPQVMGLLTNH 399 >gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] Length = 325 Score = 89.7 bits (221), Expect = 3e-18 Identities = 45/77 (58%), Positives = 57/77 (74%) Query: 30 GYPGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESR 89 G P P + +KQ+R RT FT AQL+ LE FAKT YPDIFMREE+AL+I L ESR Sbjct: 88 GGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESR 147 Query: 90 VQVWFKNRRAKCRQQQQ 106 VQVWF+NRRAK +++++ Sbjct: 148 VQVWFQNRRAKWKKRKK 164 >gi|14149760 orthopedia homeobox [Homo sapiens] Length = 325 Score = 89.7 bits (221), Expect = 3e-18 Identities = 45/77 (58%), Positives = 57/77 (74%) Query: 30 GYPGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESR 89 G P P + +KQ+R RT FT AQL+ LE FAKT YPDIFMREE+AL+I L ESR Sbjct: 88 GGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESR 147 Query: 90 VQVWFKNRRAKCRQQQQ 106 VQVWF+NRRAK +++++ Sbjct: 148 VQVWFQNRRAKWKKRKK 164 >gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] Length = 331 Score = 89.0 bits (219), Expect = 5e-18 Identities = 42/70 (60%), Positives = 52/70 (74%) Query: 42 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 101 T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC Sbjct: 136 TKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 195 Query: 102 RQQQQQQQNG 111 R+Q+ Q G Sbjct: 196 RKQENQLHKG 205 >gi|87044888 short stature homeobox 2 isoform b [Homo sapiens] Length = 190 Score = 89.0 bits (219), Expect = 5e-18 Identities = 42/70 (60%), Positives = 52/70 (74%) Query: 42 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 101 T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC Sbjct: 7 TKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 66 Query: 102 RQQQQQQQNG 111 R+Q+ Q G Sbjct: 67 RKQENQLHKG 76 >gi|152963644 paired-like homeodomain transcription factor 1 [Homo sapiens] Length = 314 Score = 88.6 bits (218), Expect = 6e-18 Identities = 62/147 (42%), Positives = 82/147 (55%), Gaps = 16/147 (10%) Query: 41 ATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAK 100 A +KQRR+RT FT QL LEA F + RYPD+ MREE+A+ NL E RV+VWFKNRRAK Sbjct: 84 AKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAK 143 Query: 101 CRQQQQQQQ----NGGQNKVRPAKKKTSPAREV-----SSESGTSGQFTP-PSSTSVPTI 150 R++++ QQ GG V P +V S + + P P ST T Sbjct: 144 WRKRERNQQLDLCKGGY--VPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTF 201 Query: 151 ASSSAPVSIWS----PASISPLSDPLS 173 +S +P+S S P+SIS ++ P S Sbjct: 202 FNSMSPLSSQSMFSAPSSISSMTMPSS 228 >gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] Length = 403 Score = 87.8 bits (216), Expect = 1e-17 Identities = 71/212 (33%), Positives = 99/212 (46%), Gaps = 40/212 (18%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+ Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276 Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163 Q Q N + P G F P T++PT+ + + + P Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315 Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209 SI +SDP ST S+ Q + P +S Y G++ T F + Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373 Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQ 241 PM+ P G LSP ++S +++ Sbjct: 374 SGPSNPMN---PTIGNGLSPQVPFIISSQISR 402 >gi|24497589 aristaless related homeobox [Homo sapiens] Length = 562 Score = 87.4 bits (215), Expect = 1e-17 Identities = 69/186 (37%), Positives = 94/186 (50%), Gaps = 24/186 (12%) Query: 11 AVNGLSLTTSGMDLLHP--SVGYPGPWASCPAA--------TPRKQRRERTTFTRAQLDV 60 A G L+ LLHP + G G + C +A RKQRR RTTFT QL+ Sbjct: 283 ATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEE 342 Query: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120 LE F KT YPD+F REE+A++++L E+RVQVWF+NRRAK R++++ G P Sbjct: 343 LERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREK----AGAQTHPPGL 398 Query: 121 KKTSP--AREVSSESGTSGQFTP--PSSTSVPTIASSSAPVSIWS------PASISPLSD 170 P A S + F P P+ S T A+++A + S AS+ P Sbjct: 399 PFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGA 458 Query: 171 PLSTSS 176 PL S+ Sbjct: 459 PLGLST 464 >gi|4826912 paired-like homeodomain 3 [Homo sapiens] Length = 302 Score = 86.7 bits (213), Expect = 2e-17 Identities = 66/180 (36%), Positives = 95/180 (52%), Gaps = 14/180 (7%) Query: 36 ASCPAATP------RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESR 89 AS P +P +KQRR+RT FT QL LEA F + RYPD+ REE+A+ NL E+R Sbjct: 46 ASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 105 Query: 90 VQVWFKNRRAKCRQQQQQQQNG--GQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSV 147 V+VWFKNRRAK R++++ QQ + P P EV G S PP + + Sbjct: 106 VRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEV--YPGYSYGNWPPKALA- 162 Query: 148 PTIASSSAPVSIWSPASISPL-SDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGG 206 P +A+ + P + ++ ++ PL S P+ + S + S + A G G G+ GG Sbjct: 163 PPLAAKTFPFA-FNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG-PGALQGLGG 220 >gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapiens] Length = 245 Score = 86.3 bits (212), Expect = 3e-17 Identities = 54/139 (38%), Positives = 71/139 (51%), Gaps = 17/139 (12%) Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103 RKQRR RTTF +QL LE +F +T YPD F+RE++A ++NL E+RVQVWF+NRRAK R+ Sbjct: 92 RKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRR 151 Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163 + + A K S + SG T VP A W A Sbjct: 152 NE---------RAMLANKNASLLKSY------SGDVTAVEQPIVPRPAPRPTDYLSWGTA 196 Query: 164 SISPLSDPLSTSSSCMQRS 182 SP S + S++C S Sbjct: 197 --SPYSAMATYSATCANNS 213 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.125 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,984,351 Number of Sequences: 37866 Number of extensions: 637083 Number of successful extensions: 4351 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 310 Number of HSP's successfully gapped in prelim test: 235 Number of HSP's that attempted gapping in prelim test: 3267 Number of HSP's gapped (non-prelim): 1120 length of query: 297 length of database: 18,247,518 effective HSP length: 102 effective length of query: 195 effective length of database: 14,385,186 effective search space: 2805111270 effective search space used: 2805111270 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.