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Search of human proteins with 11119420
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]
(297 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens] 609 e-175
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] 582 e-166
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 327 1e-89
gi|4557489 cone-rod homeobox protein [Homo sapiens] 259 3e-69
gi|61969666 arginine-fifty homeobox [Homo sapiens] 103 2e-22
gi|46249382 paired-like homeobox 2a [Homo sapiens] 100 2e-21
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 96 5e-20
gi|12707580 paired-like homeobox 2b [Homo sapiens] 95 6e-20
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 93 3e-19
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 93 3e-19
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 93 3e-19
gi|7706659 paired related homeobox 2 [Homo sapiens] 92 4e-19
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 91 1e-18
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 91 1e-18
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 91 2e-18
gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens] 90 2e-18
gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] 90 2e-18
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 90 2e-18
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 90 2e-18
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 90 2e-18
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 90 2e-18
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 90 3e-18
gi|14149760 orthopedia homeobox [Homo sapiens] 90 3e-18
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 89 5e-18
gi|87044888 short stature homeobox 2 isoform b [Homo sapiens] 89 5e-18
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 89 6e-18
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 88 1e-17
gi|24497589 aristaless related homeobox [Homo sapiens] 87 1e-17
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 87 2e-17
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 86 3e-17
>gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]
Length = 297
Score = 609 bits (1571), Expect = e-175
Identities = 297/297 (100%), Positives = 297/297 (100%)
Query: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60
MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV
Sbjct: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60
Query: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120
LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
Sbjct: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120
Query: 121 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 180
KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
Sbjct: 121 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 180
Query: 181 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 240
RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
Sbjct: 181 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 240
Query: 241 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 297
QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
Sbjct: 241 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 297
>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
Length = 289
Score = 582 bits (1500), Expect = e-166
Identities = 289/297 (97%), Positives = 289/297 (97%), Gaps = 8/297 (2%)
Query: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60
MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYP ATPRKQRRERTTFTRAQLDV
Sbjct: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYP--------ATPRKQRRERTTFTRAQLDV 52
Query: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120
LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK
Sbjct: 53 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 112
Query: 121 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 180
KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ
Sbjct: 113 KKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ 172
Query: 181 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 240
RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN
Sbjct: 173 RSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGTNAVTSHLN 232
Query: 241 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 297
QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL
Sbjct: 233 QSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFNADCLDYKDQTSSWKFQVL 289
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 327 bits (837), Expect = 1e-89
Identities = 208/371 (56%), Positives = 230/371 (61%), Gaps = 91/371 (24%)
Query: 1 MMSYLKQPPYAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLDV 60
MMSYLKQPPY +NGL L MDLLHPSVGYP ATPRKQRRERTTFTR+QLDV
Sbjct: 1 MMSYLKQPPYGMNGLGLAGPAMDLLHPSVGYP--------ATPRKQRRERTTFTRSQLDV 52
Query: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120
LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCR QQQQ+G K RPAK
Sbjct: 53 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCR---QQQQSGSGTKSRPAK 109
Query: 121 KKTSPAREVSSESGTSGQFTPP---SSTSVPTIASSS----------------------- 154
KK+SP RE SS S +SGQFTPP SS S + ASSS
Sbjct: 110 KKSSPVRE-SSGSESSGQFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSL 168
Query: 155 ---APVSIWSPASISPLSDPLSTS----------SSCMQR-----------SYPMTYTQA 190
A SIWSPASISP S P S S +SCMQR SYPM+Y Q
Sbjct: 169 STPAASSIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQG 228
Query: 191 SGYSQGY-AGSTSYFGGMDCGSYLTPMH-HQLPGPGATLSPMGTNAVTSHLNQSPAS--- 245
Y QGY S+SYFGG+DC SYL PMH H P LSPM +++ H + P +
Sbjct: 229 GSYGQGYPTPSSSYFGGVDCSSYLAPMHSHHHP---HQLSPMAPSSMAGHHHHHPHAHHP 285
Query: 246 LST-------------QGYGASSLGFNSTTDCLDYKD-----QTASWKLNFNA-DCLDYK 286
LS QGYG S L FNS DCLDYK+ +++WKLNFN+ DCLDYK
Sbjct: 286 LSQSSGHHHHHHHHHHQGYGGSGLAFNS-ADCLDYKEPGAAAASSAWKLNFNSPDCLDYK 344
Query: 287 DQTSSWKFQVL 297
DQ +SW+FQVL
Sbjct: 345 DQ-ASWRFQVL 354
>gi|4557489 cone-rod homeobox protein [Homo sapiens]
Length = 299
Score = 259 bits (661), Expect = 3e-69
Identities = 158/317 (49%), Positives = 197/317 (62%), Gaps = 38/317 (11%)
Query: 1 MMSYLKQPP-YAVNGLSLTTSGMDLLHPSVGYPGPWASCPAATPRKQRRERTTFTRAQLD 59
MM+Y+ P Y+VN L+L+ +DL+H +V YP + PRKQRRERTTFTR+QL+
Sbjct: 1 MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYP--------SAPRKQRRERTTFTRSQLE 52
Query: 60 VLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQ-----QQQQQNGGQN 114
LEALFAKT+YPD++ REEVALKINLPESRVQVWFKNRRAKCRQQ QQQQ GGQ
Sbjct: 53 ELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGGQA 112
Query: 115 KVRPAKKKTSPAREVSSE-----SGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLS 169
K RPAK+K + S++ G S ++PP + ++ A VSIWSPAS SPL
Sbjct: 113 KARPAKRKAGTSPRPSTDVCPDPLGISDSYSPPLPGPSGSPTTAVATVSIWSPASESPLP 172
Query: 170 DP-----LSTSSSCMQRSYPMTYTQASGY---SQGYAGSTSYFGGMDCGSYLTPMHHQLP 221
+ +++ S Y MTY AS + Y +SYF G+D YL+PM QL
Sbjct: 173 EAQRAGLVASGPSLTSAPYAMTYAPASAFCSSPSAYGSPSSYFSGLD--PYLSPMVPQLG 230
Query: 222 GPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNFN-A 280
GP LSP+ +V L QSP SLS Q YGA S D L++KD T +WK +N
Sbjct: 231 GP--ALSPLSGPSVGPSLAQSPTSLSGQSYGA-----YSPVDSLEFKDPTGTWKFTYNPM 283
Query: 281 DCLDYKDQTSSWKFQVL 297
D LDYKDQ S+WKFQ+L
Sbjct: 284 DPLDYKDQ-SAWKFQIL 299
>gi|61969666 arginine-fifty homeobox [Homo sapiens]
Length = 315
Score = 103 bits (256), Expect = 2e-22
Identities = 93/286 (32%), Positives = 140/286 (48%), Gaps = 37/286 (12%)
Query: 17 LTTSGMDLLHPSVGYPGPW-----ASCPAATP--RKQRRERTTFTRAQLDVLEALFAKTR 69
L SG + S+ PG AS AAT R++ +ERT+FT Q + LEALF++T
Sbjct: 42 LECSGTVSAYCSLNLPGSTDPPTSASRVAATTAIRRRHKERTSFTHQQYEELEALFSQTM 101
Query: 70 YPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAKKK--TSPAR 127
+PD ++E++AL+++LPES V+VWF+NRR K ++QQQQQ +N++ P+KK TSP
Sbjct: 102 FPDRNLQEKLALRLDLPESTVKVWFRNRRFKLKKQQQQQSAKQRNQILPSKKNVPTSPRT 161
Query: 128 EVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPASISPLSDPLSTSSSCMQ------- 180
S + F+P S ++ S S W+ S S STS MQ
Sbjct: 162 SPSPYA-----FSPVISDFYSSLPSQPLDPSNWAWNSTFTES---STSDFQMQDTQWERL 213
Query: 181 -RSYPMTYTQASG-------YSQGYAGSTSYFGGMDCGSYLTPMHHQLPGPGATLSPMGT 232
S P Y+ A Y+ S YL+P +Q+ G G++LS
Sbjct: 214 VASVPALYSDAYDIFQIIELYNLPDENEISSSSFHCLYQYLSPTKYQVGGQGSSLSIFAG 273
Query: 233 NAVTSHLNQSPASLSTQGYGASSLGFNSTTDCLDYKDQTASWKLNF 278
AV Q+ ++++Q + A SL TD L+++ + L F
Sbjct: 274 PAVGLSPAQTWPNMTSQAFEAYSL-----TDSLEFQKTSNMVDLGF 314
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 100 bits (248), Expect = 2e-21
Identities = 65/142 (45%), Positives = 83/142 (58%), Gaps = 15/142 (10%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTFT AQL LE +FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+
Sbjct: 88 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 147
Query: 104 QQQQQQNGGQNKVRPAKK---KTSPAREVSSESGTSGQFTPPSSTSV----------PTI 150
Q++ G AKK + S + S ES S TP S+ S+ P +
Sbjct: 148 QERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSP--TPDSTASLPPPPAPGLASPRL 205
Query: 151 ASSSAPVSIWSPASISPLSDPL 172
+ S PV++ S P PL
Sbjct: 206 SPSPLPVALGSGPGPGPGPQPL 227
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 95.5 bits (236), Expect = 5e-20
Identities = 48/89 (53%), Positives = 63/89 (70%), Gaps = 1/89 (1%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTFT QL+ LEA+FA+T YPD+F REE+A+KINL E+RVQVWF+NRRAK R+
Sbjct: 36 RKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWRK 95
Query: 104 QQQQQQNGGQNKVRPAKKKT-SPAREVSS 131
++ + P + T P R ++S
Sbjct: 96 TERGASDQEPGAKEPMAEVTPPPVRNINS 124
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 95.1 bits (235), Expect = 6e-20
Identities = 55/106 (51%), Positives = 70/106 (66%), Gaps = 4/106 (3%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTFT AQL LE +FA+T YPDI+ REE+ALKI+L E+RVQVWF+NRRAK R+
Sbjct: 96 RKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRK 155
Query: 104 QQQ-QQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVP 148
Q++ K + KK+ +R+ S+ S T P ST P
Sbjct: 156 QERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKS---TDPDSTGGP 198
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/186 (33%), Positives = 91/186 (48%), Gaps = 27/186 (14%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RK +R RT+FT+ Q++ LE F +T YPD+F RE +A KI+LPE+R+QVWF NRRAK R+
Sbjct: 208 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 267
Query: 104 QQQQQQNGGQNKVRPAKKKTS-----------PAREVSSESGTSGQFTPPSSTSVPTIAS 152
+++ + Q P+ S P S TSG + T++ S
Sbjct: 268 EEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYS 327
Query: 153 SSAPVSIWSPASISPLSDP-----------LSTSSSCMQRSY-----PMTYTQASGYSQG 196
+ P+ ++ A+ P+ P L TS S RSY P T + G
Sbjct: 328 ALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG 387
Query: 197 YAGSTS 202
+G+TS
Sbjct: 388 TSGTTS 393
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/186 (33%), Positives = 91/186 (48%), Gaps = 27/186 (14%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RK +R RT+FT+ Q++ LE F +T YPD+F RE +A KI+LPE+R+QVWF NRRAK R+
Sbjct: 222 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 281
Query: 104 QQQQQQNGGQNKVRPAKKKTS-----------PAREVSSESGTSGQFTPPSSTSVPTIAS 152
+++ + Q P+ S P S TSG + T++ S
Sbjct: 282 EEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYS 341
Query: 153 SSAPVSIWSPASISPLSDP-----------LSTSSSCMQRSY-----PMTYTQASGYSQG 196
+ P+ ++ A+ P+ P L TS S RSY P T + G
Sbjct: 342 ALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG 401
Query: 197 YAGSTS 202
+G+TS
Sbjct: 402 TSGTTS 407
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 92.8 bits (229), Expect = 3e-19
Identities = 62/186 (33%), Positives = 91/186 (48%), Gaps = 27/186 (14%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RK +R RT+FT+ Q++ LE F +T YPD+F RE +A KI+LPE+R+QVWF NRRAK R+
Sbjct: 208 RKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRR 267
Query: 104 QQQQQQNGGQNKVRPAKKKTS-----------PAREVSSESGTSGQFTPPSSTSVPTIAS 152
+++ + Q P+ S P S TSG + T++ S
Sbjct: 268 EEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDTALTNTYS 327
Query: 153 SSAPVSIWSPASISPLSDP-----------LSTSSSCMQRSY-----PMTYTQASGYSQG 196
+ P+ ++ A+ P+ P L TS S RSY P T + G
Sbjct: 328 ALPPMPSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNSQPMG 387
Query: 197 YAGSTS 202
+G+TS
Sbjct: 388 TSGTTS 393
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 92.4 bits (228), Expect = 4e-19
Identities = 54/151 (35%), Positives = 79/151 (52%), Gaps = 14/151 (9%)
Query: 32 PGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQ 91
P P A +KQRR RTTF +QL LE +F +T YPD F+REE+A ++NL E+RVQ
Sbjct: 90 PSPGRGSAAKRKKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQ 149
Query: 92 VWFKNRRAKCRQQQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVP--- 148
VWF+NRRAK R+ + + A + S + S E+ P + P
Sbjct: 150 VWFQNRRAKFRRNE---------RAMLASRSASLLKSYSQEAAIEQPVAPRPTALSPDYL 200
Query: 149 --TIASSSAPVSIWSPASISPLSDPLSTSSS 177
T +S + V +SP S P + ++ ++S
Sbjct: 201 SWTASSPYSTVPPYSPGSSGPATPGVNMANS 231
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 90.9 bits (224), Expect = 1e-18
Identities = 57/141 (40%), Positives = 70/141 (49%), Gaps = 16/141 (11%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ NLPE+RVQVWFKNRRAK R+
Sbjct: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163
+Q+ Q K++ +E G P T + T P + P
Sbjct: 129 KQRSLQ----------KEQLQKQKEAEGSHGEGKAEAPTPDTQLDT----EQPPRL--PG 172
Query: 164 SISPLSDPLSTSSSCMQRSYP 184
S P LS S S P
Sbjct: 173 SDPPAELHLSLSEQSASESAP 193
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 90.9 bits (224), Expect = 1e-18
Identities = 57/141 (40%), Positives = 70/141 (49%), Gaps = 16/141 (11%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RT FT QL+ LE F KT YPD+ MRE +A+ NLPE+RVQVWFKNRRAK R+
Sbjct: 64 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 123
Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163
+Q+ Q K++ +E G P T + T P + P
Sbjct: 124 KQRSLQ----------KEQLQKQKEAEGSHGEGKAEAPTPDTQLDT----EQPPRL--PG 167
Query: 164 SISPLSDPLSTSSSCMQRSYP 184
S P LS S S P
Sbjct: 168 SDPPAELHLSLSEQSASESAP 188
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 90.5 bits (223), Expect = 2e-18
Identities = 77/226 (34%), Positives = 105/226 (46%), Gaps = 45/226 (19%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLT 214
SI +SDP ST S+ Q + P +S Y ST + S++
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYC---LPSTRHGFSSYTDSFVP 372
Query: 215 PMHHQLPGPGATLSPMGTNAVTSHLNQSPASLSTQGYGASSLGFNS 260
P GP ++P N ++ Q P +S+Q SLGF S
Sbjct: 373 P-----SGPSNPMNPTIGNGLSP---QVPFIISSQ----ISLGFKS 406
>gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]
Length = 225
Score = 90.1 bits (222), Expect = 2e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 42 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 101
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172
Query: 102 RQQQQQQQNG 111
R+Q+ Q G
Sbjct: 173 RKQENQMHKG 182
>gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]
Length = 292
Score = 90.1 bits (222), Expect = 2e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 42 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 101
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172
Query: 102 RQQQQQQQNG 111
R+Q+ Q G
Sbjct: 173 RKQENQMHKG 182
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 90.1 bits (222), Expect = 2e-18
Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 216 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 275
Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163
Q Q N + P G F P T++PT+ + + + P
Sbjct: 276 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 314
Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 315 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 372
Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 238
PM+ P G LSP +T+H
Sbjct: 373 SGPSNPMN---PTIGNGLSPQVMGLLTNH 398
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 90.1 bits (222), Expect = 2e-18
Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373
Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 238
PM+ P G LSP +T+H
Sbjct: 374 SGPSNPMN---PTIGNGLSPQVMGLLTNH 399
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 90.1 bits (222), Expect = 2e-18
Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373
Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 238
PM+ P G LSP +T+H
Sbjct: 374 SGPSNPMN---PTIGNGLSPQVMGLLTNH 399
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 90.1 bits (222), Expect = 2e-18
Identities = 72/209 (34%), Positives = 97/209 (46%), Gaps = 40/209 (19%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373
Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSH 238
PM+ P G LSP +T+H
Sbjct: 374 SGPSNPMN---PTIGNGLSPQVMGLLTNH 399
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 89.7 bits (221), Expect = 3e-18
Identities = 45/77 (58%), Positives = 57/77 (74%)
Query: 30 GYPGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESR 89
G P P + +KQ+R RT FT AQL+ LE FAKT YPDIFMREE+AL+I L ESR
Sbjct: 88 GGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESR 147
Query: 90 VQVWFKNRRAKCRQQQQ 106
VQVWF+NRRAK +++++
Sbjct: 148 VQVWFQNRRAKWKKRKK 164
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 89.7 bits (221), Expect = 3e-18
Identities = 45/77 (58%), Positives = 57/77 (74%)
Query: 30 GYPGPWASCPAATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESR 89
G P P + +KQ+R RT FT AQL+ LE FAKT YPDIFMREE+AL+I L ESR
Sbjct: 88 GGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESR 147
Query: 90 VQVWFKNRRAKCRQQQQ 106
VQVWF+NRRAK +++++
Sbjct: 148 VQVWFQNRRAKWKKRKK 164
>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
Length = 331
Score = 89.0 bits (219), Expect = 5e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 42 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 101
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 136 TKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 195
Query: 102 RQQQQQQQNG 111
R+Q+ Q G
Sbjct: 196 RKQENQLHKG 205
>gi|87044888 short stature homeobox 2 isoform b [Homo sapiens]
Length = 190
Score = 89.0 bits (219), Expect = 5e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 42 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 101
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 7 TKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 66
Query: 102 RQQQQQQQNG 111
R+Q+ Q G
Sbjct: 67 RKQENQLHKG 76
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 88.6 bits (218), Expect = 6e-18
Identities = 62/147 (42%), Positives = 82/147 (55%), Gaps = 16/147 (10%)
Query: 41 ATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAK 100
A +KQRR+RT FT QL LEA F + RYPD+ MREE+A+ NL E RV+VWFKNRRAK
Sbjct: 84 AKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAK 143
Query: 101 CRQQQQQQQ----NGGQNKVRPAKKKTSPAREV-----SSESGTSGQFTP-PSSTSVPTI 150
R++++ QQ GG V P +V S + + P P ST T
Sbjct: 144 WRKRERNQQLDLCKGGY--VPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTF 201
Query: 151 ASSSAPVSIWS----PASISPLSDPLS 173
+S +P+S S P+SIS ++ P S
Sbjct: 202 FNSMSPLSSQSMFSAPSSISSMTMPSS 228
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 87.8 bits (216), Expect = 1e-17
Identities = 71/212 (33%), Positives = 99/212 (46%), Gaps = 40/212 (18%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTFT QL+ LE F +T YPDI+ REE+A + L E+RVQVWF NRRA+ R+
Sbjct: 217 RKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRK 276
Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163
Q Q N + P G F P T++PT+ + + + P
Sbjct: 277 QAGANQLMAFNHLIP------------------GGFPP---TAMPTLPTYQLSETSYQPT 315
Query: 164 SI-SPLSDPLST--------SSSCMQRSYPMTYTQASGY-----SQGYAGSTSYFGGMDC 209
SI +SDP ST S+ Q + P +S Y G++ T F +
Sbjct: 316 SIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSNPDSSSAYCLPSTRHGFSSYTDSF--VPP 373
Query: 210 GSYLTPMHHQLPGPGATLSPMGTNAVTSHLNQ 241
PM+ P G LSP ++S +++
Sbjct: 374 SGPSNPMN---PTIGNGLSPQVPFIISSQISR 402
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 87.4 bits (215), Expect = 1e-17
Identities = 69/186 (37%), Positives = 94/186 (50%), Gaps = 24/186 (12%)
Query: 11 AVNGLSLTTSGMDLLHP--SVGYPGPWASCPAA--------TPRKQRRERTTFTRAQLDV 60
A G L+ LLHP + G G + C +A RKQRR RTTFT QL+
Sbjct: 283 ATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEE 342
Query: 61 LEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQQNGGQNKVRPAK 120
LE F KT YPD+F REE+A++++L E+RVQVWF+NRRAK R++++ G P
Sbjct: 343 LERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREK----AGAQTHPPGL 398
Query: 121 KKTSP--AREVSSESGTSGQFTP--PSSTSVPTIASSSAPVSIWS------PASISPLSD 170
P A S + F P P+ S T A+++A + S AS+ P
Sbjct: 399 PFPGPLSATHPLSPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGA 458
Query: 171 PLSTSS 176
PL S+
Sbjct: 459 PLGLST 464
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 86.7 bits (213), Expect = 2e-17
Identities = 66/180 (36%), Positives = 95/180 (52%), Gaps = 14/180 (7%)
Query: 36 ASCPAATP------RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESR 89
AS P +P +KQRR+RT FT QL LEA F + RYPD+ REE+A+ NL E+R
Sbjct: 46 ASLPGGSPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEAR 105
Query: 90 VQVWFKNRRAKCRQQQQQQQNG--GQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSV 147
V+VWFKNRRAK R++++ QQ + P P EV G S PP + +
Sbjct: 106 VRVWFKNRRAKWRKRERSQQAELCKGSFAAPLGGLVPPYEEV--YPGYSYGNWPPKALA- 162
Query: 148 PTIASSSAPVSIWSPASISPL-SDPLSTSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGG 206
P +A+ + P + ++ ++ PL S P+ + S + S + A G G G+ GG
Sbjct: 163 PPLAAKTFPFA-FNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGTVPG-PGALQGLGG 220
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 86.3 bits (212), Expect = 3e-17
Identities = 54/139 (38%), Positives = 71/139 (51%), Gaps = 17/139 (12%)
Query: 44 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQ 103
RKQRR RTTF +QL LE +F +T YPD F+RE++A ++NL E+RVQVWF+NRRAK R+
Sbjct: 92 RKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRR 151
Query: 104 QQQQQQNGGQNKVRPAKKKTSPAREVSSESGTSGQFTPPSSTSVPTIASSSAPVSIWSPA 163
+ + A K S + SG T VP A W A
Sbjct: 152 NE---------RAMLANKNASLLKSY------SGDVTAVEQPIVPRPAPRPTDYLSWGTA 196
Query: 164 SISPLSDPLSTSSSCMQRS 182
SP S + S++C S
Sbjct: 197 --SPYSAMATYSATCANNS 213
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.125 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,984,351
Number of Sequences: 37866
Number of extensions: 637083
Number of successful extensions: 4351
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 310
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 3267
Number of HSP's gapped (non-prelim): 1120
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.