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Search of human proteins with 111185957
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens]
(504 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens] 1028 0.0
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 54 3e-07
gi|47575849 docking protein 6 [Homo sapiens] 46 9e-05
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] 44 3e-04
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 44 3e-04
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 44 3e-04
gi|22538470 eomesodermin [Homo sapiens] 43 8e-04
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 43 8e-04
gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] 42 0.002
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 42 0.002
gi|20070302 docking protein 4 [Homo sapiens] 41 0.002
gi|29544726 docking protein 5 [Homo sapiens] 41 0.002
gi|6912492 mitogen-activated protein kinase 8 interacting protei... 41 0.002
gi|7706537 mitogen-activated protein kinase 8 interacting protei... 41 0.002
gi|221139926 NHS-like 1 [Homo sapiens] 40 0.004
gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 40 0.004
gi|92859678 small nuclear RNA activating complex, polypeptide 4,... 40 0.004
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 40 0.005
gi|30039694 zinc finger protein 598 [Homo sapiens] 40 0.005
gi|33286446 opioid growth factor receptor [Homo sapiens] 40 0.006
gi|5730059 fibroblast growth factor receptor substrate 3 [Homo s... 40 0.006
gi|171906567 peripheral benzodiazepine receptor-associated prote... 40 0.006
gi|171906559 peripheral benzodiazepine receptor-associated prote... 40 0.006
gi|239753407 PREDICTED: hypothetical protein [Homo sapiens] 39 0.008
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 39 0.008
gi|110556644 zinc finger protein, multitype 1 [Homo sapiens] 39 0.011
gi|83367077 mucin 16 [Homo sapiens] 39 0.014
gi|169162742 PREDICTED: hypothetical protein [Homo sapiens] 39 0.014
gi|55956910 meningioma 1 [Homo sapiens] 39 0.014
>gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens]
Length = 504
Score = 1028 bits (2658), Expect = 0.0
Identities = 504/504 (100%), Positives = 504/504 (100%)
Query: 1 MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDKSERIKGLRERSSLTLE 60
MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDKSERIKGLRERSSLTLE
Sbjct: 1 MTEAALVEGQVKLRDGKKWKSRWLVLRKPSPVADCLLMLVYKDKSERIKGLRERSSLTLE 60
Query: 61 DICGLEPGLPYEGLVHTLAIVCLSQAIMLGFDSHEAMCAWDARIRYALGEVHRFHVTVAP 120
DICGLEPGLPYEGLVHTLAIVCLSQAIMLGFDSHEAMCAWDARIRYALGEVHRFHVTVAP
Sbjct: 61 DICGLEPGLPYEGLVHTLAIVCLSQAIMLGFDSHEAMCAWDARIRYALGEVHRFHVTVAP 120
Query: 121 GTKLESGPATLHLCNDVLVLARDIPPAVTGQWKLSDLRRYGAVPSGFIFEGGTRCGYWAG 180
GTKLESGPATLHLCNDVLVLARDIPPAVTGQWKLSDLRRYGAVPSGFIFEGGTRCGYWAG
Sbjct: 121 GTKLESGPATLHLCNDVLVLARDIPPAVTGQWKLSDLRRYGAVPSGFIFEGGTRCGYWAG 180
Query: 181 VFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDPSPPGPSTVEERVAQEALETLQ 240
VFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDPSPPGPSTVEERVAQEALETLQ
Sbjct: 181 VFFLSSAEGEQISFLFDCIVRGISPTKGPFGLRPVLPDPSPPGPSTVEERVAQEALETLQ 240
Query: 241 LEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPR 300
LEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPR
Sbjct: 241 LEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPR 300
Query: 301 PAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSL 360
PAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSL
Sbjct: 301 PAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSL 360
Query: 361 DVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSP 420
DVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSP
Sbjct: 361 DVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSP 420
Query: 421 PSQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPGEPWEAGGP 480
PSQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPGEPWEAGGP
Sbjct: 421 PSQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPGEPWEAGGP 480
Query: 481 HAGPPPAFFSACPVCGGLKVNPPP 504
HAGPPPAFFSACPVCGGLKVNPPP
Sbjct: 481 HAGPPPAFFSACPVCGGLKVNPPP 504
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 53.9 bits (128), Expect = 3e-07
Identities = 66/226 (29%), Positives = 91/226 (40%), Gaps = 31/226 (13%)
Query: 221 PPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSR 280
PP + ++ A AL+ + E+R S S + S S SSSSS S S S
Sbjct: 2509 PPASTGAQQPSALAALQPAK-ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567
Query: 281 LTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPP-PKPLRPRQLQEVGRQSSSDSG 339
L PE + + P PA +A E RPP P P + + R+SSS S
Sbjct: 2568 LPVQPEVALKRVPS----PTPAPKEAVRE-----GRPPEPTPAKRK------RRSSSSSS 2612
Query: 340 IATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPT 399
++ S SS SSS SS + SS ++ S S P+ P P LP + P
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ---ALPKPASPKKPP 2669
Query: 400 SLRAHYDTP----------RSLCLAPRDHSPPS-QGSPGNSAARDS 434
+P RSL +P + PS Q SP + + S
Sbjct: 2670 PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSS 2715
Score = 42.4 bits (98), Expect = 0.001
Identities = 55/218 (25%), Positives = 88/218 (40%), Gaps = 28/218 (12%)
Query: 275 VSASSRLTAWPEQSSSSASTSQEG----PRPAAAQA-AGEAMVGASRPPPKPLRPRQLQE 329
V+ S L++ +++S++ G P P + GE P L Q +
Sbjct: 2469 VAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAK 2528
Query: 330 VGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCL 389
R SSS S ++ S SS SSS SS + S ++D GS SLP PE +L
Sbjct: 2529 ERRSSSSSSSSSSSSSSSSSSSSSSSSSGS----SSSDSEGS--SLPV--QPEVAL---- 2576
Query: 390 PGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQTSAGCPSGWLGT 449
+VP+ A + R P + +P + +S++ S +S+ S +
Sbjct: 2577 -----KRVPSPTPAPKEAVRE--GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
Query: 450 RRRGLVMEAPQGSEATLPGPAPGEPWEAGGPHAGPPPA 487
+ S ++ P+P +P GP A P PA
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKP----GPQALPKPA 2663
Score = 37.7 bits (86), Expect = 0.025
Identities = 35/110 (31%), Positives = 47/110 (42%), Gaps = 12/110 (10%)
Query: 216 LPDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDV 275
+P P+P V E E T KR S S + S S SSSSS +S
Sbjct: 2579 VPSPTPAPKEAVREGRPPEP--TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS---- 2632
Query: 276 SASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPR 325
S+SS ++ SSSS S ++ GP+ A+ +PPP R R
Sbjct: 2633 SSSSSSSSSSSSSSSSPSPAKPGPQALPKPAS------PKKPPPGERRSR 2676
Score = 37.4 bits (85), Expect = 0.032
Identities = 63/295 (21%), Positives = 93/295 (31%), Gaps = 48/295 (16%)
Query: 217 PDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVS 276
P P PP P ++ + T + +K+ R S R SS + H S
Sbjct: 163 PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
Query: 277 ASSR------------------------LTAWPE----------QSSSSASTSQEGPRPA 302
S + T P+ S+SS+ TS+ R A
Sbjct: 223 ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSA 282
Query: 303 AAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLD- 361
AA+ A+ G S P R ++ + + ++ S Y D
Sbjct: 283 AAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDK 342
Query: 362 ----VWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRD 417
R + + P AP P L G+ + T L P S RD
Sbjct: 343 KEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRD 402
Query: 418 HSPPSQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPG 472
SPP SP + S ++S P +R E+P+ P PAPG
Sbjct: 403 RSPPK--SP-EKLPQSSSSESSPPSPQPTKVSRHASSSPESPK------PAPAPG 448
Score = 32.3 bits (72), Expect = 1.0
Identities = 28/91 (30%), Positives = 36/91 (39%), Gaps = 5/91 (5%)
Query: 263 LSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPL 322
L S S +V + SRL+ +S SS ++ PR A +G S P PK
Sbjct: 1573 LRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEV-KDKPRAAPRAQSG----SDSSPEPKAP 1627
Query: 323 RPRQLQEVGRQSSSDSGIATGSHSSYSSSLS 353
PR L R SS G S S+ S
Sbjct: 1628 APRALPRRSRSGSSSKGRGPSPEGSSSTESS 1658
Score = 30.8 bits (68), Expect = 3.0
Identities = 51/220 (23%), Positives = 77/220 (35%), Gaps = 7/220 (3%)
Query: 260 DRSLSSSSSEASHLDVSASSRL-TAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPP 318
D L S + S+ R+ ++ P + S S S+S + A + G+S P
Sbjct: 878 DPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPS 937
Query: 319 PKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSL--DVWRATDELGSLLSLP 376
P + R R S S + + YS S SS + + + GS+ P
Sbjct: 938 PSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP 997
Query: 377 AAGA---PEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARD 433
A P PSL + + SL SLC + +PP + G S+ +
Sbjct: 998 KVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQL 1057
Query: 434 SG-GQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPG 472
G QTS S R E+P + P G
Sbjct: 1058 KGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGG 1097
>gi|47575849 docking protein 6 [Homo sapiens]
Length = 331
Score = 45.8 bits (107), Expect = 9e-05
Identities = 58/214 (27%), Positives = 88/214 (41%), Gaps = 34/214 (15%)
Query: 8 EGQVKLRDGKK--WKSRWLVLRKPSPVADCLLMLVYKDKSERIKGLRERSSL-TLEDICG 64
+G VK+R K ++ WLV +K S L +K+ + + + L +++I
Sbjct: 11 QGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVTELHNIKNITR 70
Query: 65 LEPGLPYEGLVHTLAIV----------CLSQAIMLGFDSHEAMCAWDARIR-YALGEV-- 111
L P E H +AI+ C S+ + H M R+ +LGE
Sbjct: 71 L----PRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDISLGEPDL 126
Query: 112 ----------HRFHVTVAPGTKLES-GPATLHLCNDVLVLARDIPPAVTG--QWKLSDLR 158
RF+V + P L+ G T+ + ++ + L DI A W LS LR
Sbjct: 127 LAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLW-DIHNAKVKLVMWPLSSLR 185
Query: 159 RYGAVPSGFIFEGGTRCGYWAGVFFLSSAEGEQI 192
RYG + F FE G C G+F + EGE I
Sbjct: 186 RYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMI 219
>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
Length = 625
Score = 44.3 bits (103), Expect = 3e-04
Identities = 62/198 (31%), Positives = 83/198 (41%), Gaps = 22/198 (11%)
Query: 230 RVAQEALETLQLEKRLSLLS-HAGRPGSGGDD-RSLSSSSSEASHLDVSASSRLTAWPEQ 287
RVA E + E+R L A R ++ R L + S A+ +A+S +A
Sbjct: 145 RVATGLYEAYEAERRAKLQQCRAERDRIMREEKRRLFTPLSPAAAAAAAAASAPSAGSSS 204
Query: 288 SSSSASTSQEGPRPAAAQAAGEAMVGA-SRPPPKPLRPRQLQEVGRQSSSDSGIATGSHS 346
S SSAS P P AA+ A + A ++PPP R GR+S S ++
Sbjct: 205 SCSSASL-PASPAPRAARKASPSPSSARTQPPPAGSR------TGRKSHSLDSLSRRREG 257
Query: 347 SYSS----SLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLR 402
+ SS S SSY+G SL R + S PA A S T PG P++L
Sbjct: 258 ALSSESGASSSSYSGESLRELRWPPRASARNSCPAGSA---SSTTNAPGR-----PSALT 309
Query: 403 AHYDTPRSLCLAPRDHSP 420
T RS L HSP
Sbjct: 310 LVPITGRSFSLGDLSHSP 327
>gi|74027251 tripartite motif-containing 33 protein isoform beta
[Homo sapiens]
Length = 1110
Score = 43.9 bits (102), Expect = 3e-04
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 427 GNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPGEPWEAGGPHAGPPP 486
G AA SG +A P+ +GT G + P + A+ P P P + GP GPP
Sbjct: 65 GGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGP-----SAGPPPGPPA 119
Query: 487 AFFSACPVC 495
+ C VC
Sbjct: 120 SLLDTCAVC 128
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 43.9 bits (102), Expect = 3e-04
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 5/69 (7%)
Query: 427 GNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPGEPWEAGGPHAGPPP 486
G AA SG +A P+ +GT G + P + A+ P P P + GP GPP
Sbjct: 65 GGVAAASSGSAQAASSPAASVGTGVAGGAVSTPAPAPASAPAPGP-----SAGPPPGPPA 119
Query: 487 AFFSACPVC 495
+ C VC
Sbjct: 120 SLLDTCAVC 128
>gi|22538470 eomesodermin [Homo sapiens]
Length = 686
Score = 42.7 bits (99), Expect = 8e-04
Identities = 63/240 (26%), Positives = 92/240 (38%), Gaps = 36/240 (15%)
Query: 251 AGRPGSGGDDRSLSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQA---- 306
+ R GSGG L S++ LD+ +S+ + S S S PAAA A
Sbjct: 24 SARGGSGGSAGHLPSAAPSPQKLDLDKASK------KFSGSLSCEAVSGEPAAASAGAPA 77
Query: 307 -------AGEAMVGASR-PPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGS 358
AG+A A+ P P R+ G + + A + ++ +++ + Y+
Sbjct: 78 AMLSDTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMD 137
Query: 359 SLDVWR----ATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLA 414
SL R + GS L+ P + P + G V Y P R Y +
Sbjct: 138 SLSSERYYLQSPGPQGSELAAPCSLFPYQAAAGAPHGPV-YPAPNGARYPYGSMLPPGGF 196
Query: 415 PRDHSPP--SQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPG 472
P PP +Q PG A +GG + G G GT + QG A L GP PG
Sbjct: 197 PAAVCPPGRAQFGPGAGAGSGAGGSSGGG---GGPGT------YQYSQG--APLYGPYPG 245
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 42.7 bits (99), Expect = 8e-04
Identities = 59/222 (26%), Positives = 82/222 (36%), Gaps = 17/222 (7%)
Query: 218 DPSPPGPSTVEERVAQEALETLQLEKRLSLLS-HAGRPGSGGDDRSLSSSSSEASHLDVS 276
+P P P + +AQE L E + S + G + S SSSSS + S
Sbjct: 2512 EPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSS 2571
Query: 277 ASSRLTAWPEQSSSSASTSQEG------------PRPAAAQAAGEAMVGASRPPPKPLRP 324
+SS + + + +G AA+ A+ + +S
Sbjct: 2572 SSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSS 2631
Query: 325 RQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLS-LPAAGAPE- 382
SSS S ++ S SS SSS SS + SS TDE S S AA AP
Sbjct: 2632 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTA 2691
Query: 383 -PSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQ 423
PS LP Q + R +P AP+ +PP Q
Sbjct: 2692 GPSAQAALPTKATKQAGKA-RPSAHSPGKKTPAPQPQAPPPQ 2732
>gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/160 (31%), Positives = 68/160 (42%), Gaps = 20/160 (12%)
Query: 266 SSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGA-SRPPPKPLRP 324
S + A+ +A+S +A S SSAS P P AA+ A + A ++PPP R
Sbjct: 185 SPAAAAAAAAAAASAPSAGSSSSCSSASLPAS-PAPRAARKASPSPSSARTQPPPAGSR- 242
Query: 325 RQLQEVGRQSSSDSGIATGSHSSYSS----SLSSYAGSSLDVWRATDELGSLLSLPAAGA 380
GR+S S ++ + SS S SSY+G SL R + S PA A
Sbjct: 243 -----TGRKSHSLDSLSRRREGALSSESGASSSSYSGESLRELRWPPRASARNSCPAGSA 297
Query: 381 PEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSP 420
S T PG P++L T RS L HSP
Sbjct: 298 ---SSTTNAPGR-----PSALTLVPITGRSFSLGDLSHSP 329
>gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/160 (31%), Positives = 68/160 (42%), Gaps = 20/160 (12%)
Query: 266 SSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGA-SRPPPKPLRP 324
S + A+ +A+S +A S SSAS P P AA+ A + A ++PPP R
Sbjct: 185 SPAAAAAAAAAAASAPSAGSSSSCSSASLPAS-PAPRAARKASPSPSSARTQPPPAGSR- 242
Query: 325 RQLQEVGRQSSSDSGIATGSHSSYSS----SLSSYAGSSLDVWRATDELGSLLSLPAAGA 380
GR+S S ++ + SS S SSY+G SL R + S PA A
Sbjct: 243 -----TGRKSHSLDSLSRRREGALSSESGASSSSYSGESLRELRWPPRASARNSCPAGSA 297
Query: 381 PEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSP 420
S T PG P++L T RS L HSP
Sbjct: 298 ---SSTTNAPGR-----PSALTLVPITGRSFSLGDLSHSP 329
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 41.6 bits (96), Expect = 0.002
Identities = 74/278 (26%), Positives = 94/278 (33%), Gaps = 70/278 (25%)
Query: 262 SLSSSSSEASHLDVSASSRLTAWP-----EQSSSSASTSQEGPRPAAAQAAGEAMVGASR 316
SL +S ++H D + RL A E S ++ +G P + G + A
Sbjct: 1547 SLPPASQASNHRDPRQARRLAAETGEGEGEPLSRLSARGAQGALPERDASRGGLVGQAPM 1606
Query: 317 PPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGS----- 371
P P+ P + S ++S AGS D W+A G+
Sbjct: 1607 PVPEEKEP-------------------ASSPWASGEKPPAGSEQDGWKAEPGEGTRPATV 1647
Query: 372 -----------LLSLPAAGAPEPSL----------CTCLPGTVEYQVPTSLRAHYDTPRS 410
LL P GA +P TC PG A Y+ PR+
Sbjct: 1648 GDSSARPARRVLLPTPPCGALQPGFPLQHDGERDPFTC-PGFASQDKALG-SAQYEDPRN 1705
Query: 411 LCLAPRDHSPPS--------QGSPG-NSAARDSGGQTSAGCPSGWLGTRRRG---LVMEA 458
L A R SP Q PG +A GQ G + G R G L M
Sbjct: 1706 LHSAGRSSSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSG 1765
Query: 459 PQGSEATLP-GPAPGEPWE----AGGPHAGPPPAFFSA 491
G P GPAP P E GP GPPPA F A
Sbjct: 1766 LHGPNFPGPRGPAPPFPEENIASNDGPR-GPPPARFGA 1802
Score = 35.0 bits (79), Expect = 0.16
Identities = 47/187 (25%), Positives = 70/187 (37%), Gaps = 37/187 (19%)
Query: 217 PDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGS--GGDDRSLSSSSSEASHLD 274
P PS ST E+R ++E + K+ + PGS G + ++S +
Sbjct: 522 PSPSLLYKSTKEDRRSEEKAAAMAASKKTA------PPGSAVGKQPAPRNLVPKKSSFAN 575
Query: 275 VSASSRLTAWPEQ----------------SSSSASTSQEGPRPAAAQAAGE------AMV 312
V+A++ P SS +++ Q GP PAAA AA + A+V
Sbjct: 576 VAAATPAIKKPPSGFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALV 635
Query: 313 GASRPPPKPLRPRQLQEVGR-------QSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRA 365
GA R P P P GR S +S I S L S D+
Sbjct: 636 GAVRKPVVPSVPMASPAPGRLGAMSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMT 695
Query: 366 TDELGSL 372
+E+G +
Sbjct: 696 ENEVGKI 702
>gi|20070302 docking protein 4 [Homo sapiens]
Length = 326
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Query: 110 EVHRFHVTVAPGTKLES-GPATLHLCNDVLVLARDIPPAVT-GQWKLSDLRRYGAVPSGF 167
+ RF+V + P L+ G L + ++ + L P V W L LRRYG + F
Sbjct: 135 QTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRF 194
Query: 168 IFEGGTRCGYWAGVFFLSSAEGEQI 192
FE G C G++ + EGEQI
Sbjct: 195 TFEAGRMCDAGEGLYTFQTQEGEQI 219
>gi|29544726 docking protein 5 [Homo sapiens]
Length = 306
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 113 RFHVTVAPGTKLE-SGPATLHLCNDVLVLARDIPPAVTG-QWKLSDLRRYGAVPSGFIFE 170
RF+V + P L+ G L + + + L P V W LS LRRYG + F FE
Sbjct: 138 RFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFE 197
Query: 171 GGTRCGYWAGVFFLSSAEGEQI 192
G C G+F + +GE I
Sbjct: 198 AGRMCETGEGLFIFQTRDGEAI 219
>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
isoform 1 [Homo sapiens]
Length = 824
Score = 41.2 bits (95), Expect = 0.002
Identities = 78/303 (25%), Positives = 102/303 (33%), Gaps = 64/303 (21%)
Query: 211 GLRPVLPDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEA 270
G RP P P+P G S + +E L S GR G + LSS S++
Sbjct: 208 GNRPAEP-PAPGGTSPSSDP---------GIEADLRSRSSGGR-GGRRSSQELSSPGSDS 256
Query: 271 SHLDVSASSRLTAWPEQS----SSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPRQ 326
+ R+ + ++ SS +S G + EA AS P P PR+
Sbjct: 257 EDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRR 316
Query: 327 --LQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPS 384
VG ++S +GS S LS A S W L +L+S + P
Sbjct: 317 PAFLPVG-PDDTNSEYESGSESE--PDLSEDADSP---WL----LSNLVSRMISEGSSPI 366
Query: 385 LCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQTSAGCPS 444
C PG CL+P P SP AA+DS +A P
Sbjct: 367 RC---PGQ-------------------CLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPG 404
Query: 445 GWLGTRRRGLVMEAPQGSEATLPGPAPGEP---------------WEAGGPHAGPPPAFF 489
G L P A PGPA P W A G A P A
Sbjct: 405 GVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACS 464
Query: 490 SAC 492
+AC
Sbjct: 465 AAC 467
>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
isoform 2 [Homo sapiens]
Length = 797
Score = 41.2 bits (95), Expect = 0.002
Identities = 78/303 (25%), Positives = 102/303 (33%), Gaps = 64/303 (21%)
Query: 211 GLRPVLPDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEA 270
G RP P P+P G S + +E L S GR G + LSS S++
Sbjct: 181 GNRPAEP-PAPGGTSPSSDP---------GIEADLRSRSSGGR-GGRRSSQELSSPGSDS 229
Query: 271 SHLDVSASSRLTAWPEQS----SSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPRQ 326
+ R+ + ++ SS +S G + EA AS P P PR+
Sbjct: 230 EDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRR 289
Query: 327 --LQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPS 384
VG ++S +GS S LS A S W L +L+S + P
Sbjct: 290 PAFLPVG-PDDTNSEYESGSESE--PDLSEDADSP---WL----LSNLVSRMISEGSSPI 339
Query: 385 LCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQTSAGCPS 444
C PG CL+P P SP AA+DS +A P
Sbjct: 340 RC---PGQ-------------------CLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPG 377
Query: 445 GWLGTRRRGLVMEAPQGSEATLPGPAPGEP---------------WEAGGPHAGPPPAFF 489
G L P A PGPA P W A G A P A
Sbjct: 378 GVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACS 437
Query: 490 SAC 492
+AC
Sbjct: 438 AAC 440
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 40.4 bits (93), Expect = 0.004
Identities = 71/282 (25%), Positives = 113/282 (40%), Gaps = 49/282 (17%)
Query: 214 PVLPDPSPPGPSTVEERVAQEALE-TLQLEKRLSLLS--HAG-----RPGSGGDDRSLSS 265
P+ P + PG ST ++ +L+ T E SL S H G SG +L +
Sbjct: 565 PLKPHLATPGYSTPTSNMSSCSLDQTSNKEDAGSLYSEDHDGYCASVHTDSGHGSGNLCN 624
Query: 266 SSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPR 325
SS + S + +++ S Q+ + + ++ A +PP P R
Sbjct: 625 SSDGFGNPRHSVINVFVGRAQKNQGDRSNYQD-----KSLSRNISLKKAKKPPLPPSRTD 679
Query: 326 QLQEVGRQSSSDSG-------IATGSHS--------SYSSSLSSYAGSSLDVW----RAT 366
L+ + ++SS +G IAT HS S SS S + W R+
Sbjct: 680 SLRRIPKKSSQCNGQVLNESLIATLQHSLQLSLPGKSGSSPSQSPCSDLEEPWLPRSRSQ 739
Query: 367 DELGSLLSLPAAGAPEP-SLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGS 425
+ + S+ +A P SLC P + +S+++ Y P + D++ Q
Sbjct: 740 STVSAGSSMTSATTPNVYSLCGATPSQSD---TSSVKSEYTDPWGYYI---DYTG-MQED 792
Query: 426 PGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLP 467
PGN A G TS+G P+G G V +GS AT+P
Sbjct: 793 PGNPAG---GCSTSSGVPTG------NGPVRHVQEGSRATMP 825
>gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens]
Length = 2382
Score = 40.4 bits (93), Expect = 0.004
Identities = 79/319 (24%), Positives = 116/319 (36%), Gaps = 76/319 (23%)
Query: 202 GISPTKGPFGLRPVLPD--------------PSPPGPSTVEERVAQEALETLQLEKRLSL 247
G +P+K P PVLP P PGPS + +Q+ LE L + R +L
Sbjct: 1748 GTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQ---SQQPLEDLDAQLRRTL 1804
Query: 248 LSHAGRPGSGGDDRSLSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAA 307
+ + +S + ++A + +T Q S +EGP A + A
Sbjct: 1805 ------------SPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATSSGA 1852
Query: 308 GEAMVGASRPPPKPLRPRQLQEVGRQSSSDS-GIATGSHSSYSSSLSSYAGSSLDVWRAT 366
G +G + + Q+ G+ S D+ + S +S SS LSS + S V
Sbjct: 1853 GVFKMGRFQVS---VAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLV---- 1905
Query: 367 DELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQ--- 423
PEP+ T +PG + VP S AH T A D P++
Sbjct: 1906 -------------KPEPNGIT-IPG-ISSDVPES--AHKTTASE---AKSDTGQPTKVGR 1945
Query: 424 ---GSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAP--QGSEATLPGPAP------- 471
+ N R S +T T++ G V P +A LP P
Sbjct: 1946 FQVTTTANKVGRFSVSKTEDKITD----TKKEGPVASPPFMDLEQAVLPAVIPKKEKPEL 2001
Query: 472 GEPWEAGGPHAGPPPAFFS 490
EP GP + P AF S
Sbjct: 2002 SEPSHLNGPSSDPEAAFLS 2020
>gi|92859678 small nuclear RNA activating complex, polypeptide 4,
190kDa [Homo sapiens]
Length = 1469
Score = 40.4 bits (93), Expect = 0.004
Identities = 60/242 (24%), Positives = 91/242 (37%), Gaps = 34/242 (14%)
Query: 264 SSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASR-----PP 318
SS+ S HL + ++ +S S S +G R A+ + AS P
Sbjct: 836 SSAQSTPGHLFPNVPAQ--------EASKSASHKGSRRLASSRVERTLPQASLLASTGPR 887
Query: 319 PKP------LRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSL 372
PKP L+ ++LQE + ++ + S SSS+ ++
Sbjct: 888 PKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTV 947
Query: 373 LSLPAAGAPEPSLCTCLPGTVE--YQVPTSLR-AHYDTPRSLCLAPRDHSPPSQGSPGNS 429
L++P +G P+ PGT + TS + T ++L LAP +
Sbjct: 948 LNVPLSGPGAPAAAK--PGTSGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQ 1005
Query: 430 AARDSGGQTSAGCPSGWLG-------TRRRGLVMEAPQGSEATLPGPAPGEP---WEAGG 479
A GQ S CP LG +R++GL P A P P P +P GG
Sbjct: 1006 APALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGG 1065
Query: 480 PH 481
PH
Sbjct: 1066 PH 1067
Score = 33.5 bits (75), Expect = 0.46
Identities = 43/162 (26%), Positives = 60/162 (37%), Gaps = 24/162 (14%)
Query: 276 SASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSS 335
S SS ++ SSSS+S+ ++ P A A A++ P + L RQS+
Sbjct: 524 SGSSSGSSGGSSSSSSSSSEEDEPEQAQAGEGDRALLS----PQYMVPDMDLWVPARQST 579
Query: 336 SDS--GIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTV 393
S G A ++SLS GSS G+ E S PG
Sbjct: 580 SQPWRGGAGAWLGGPAASLSPPKGSSAS---------------QGGSKEASTTAAAPGEE 624
Query: 394 EYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSG 435
V RAH PRS A HS ++ + A + G
Sbjct: 625 TSPVQVPARAHGPVPRS---AQASHSADTRPAGAEKQALEGG 663
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 40.0 bits (92), Expect = 0.005
Identities = 45/178 (25%), Positives = 70/178 (39%), Gaps = 30/178 (16%)
Query: 220 SPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASS 279
SPP P + + +L L S L +G PG+ D R S S ++++ SS
Sbjct: 932 SPPAPPLLASAASSSSL--LSASSPASSLG-SGTPGTSSDSRQRSPLSD---YMNLDFSS 985
Query: 280 RLTAWPEQSSSSASTSQEG--------------PRPAAAQAAGEAMVGASRPPPKPLRPR 325
+ P S S +G PRP+A+ ++ + +PPP P P
Sbjct: 986 PKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSS------SLQPPPPPPAPG 1039
Query: 326 QLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEP 383
+L + S +AT +SSLSS G + D + + P A P+P
Sbjct: 1040 ELYRL----PPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKP 1093
Score = 34.7 bits (78), Expect = 0.21
Identities = 68/288 (23%), Positives = 91/288 (31%), Gaps = 57/288 (19%)
Query: 257 GGDDRSLSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQE--GPRPAAAQAAGEAMVGA 314
G DD + + A S S R + S +S S ++ PR AAA AA G
Sbjct: 648 GADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGP 707
Query: 315 SRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDEL---GS 371
+ P P R G + S S S + + GS L + A +L G
Sbjct: 708 AGPAPTSAAGRTFPASGGGYKASS--PAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGD 765
Query: 372 LLSLP-----AAGAPEPSLCTCL----------PGTVEYQVPTSLRAHY----------- 405
L++ G P L PG +P S +A Y
Sbjct: 766 YLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVL 825
Query: 406 -DTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQT-------------SAGCPSGWLGTRR 451
+P L P + P +A+ G T S G P G+LG R
Sbjct: 826 MSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRG 885
Query: 452 RGL---------VMEAPQGSEATLPGPAPGEPWEAGGPHAGPPPAFFS 490
R + + P E LP P P P E G P A S
Sbjct: 886 RAVRPTRLSLEGLPSLPSMHEYPLP-PEPKSPGEYINIDFGEPGARLS 932
>gi|30039694 zinc finger protein 598 [Homo sapiens]
Length = 904
Score = 40.0 bits (92), Expect = 0.005
Identities = 67/288 (23%), Positives = 109/288 (37%), Gaps = 53/288 (18%)
Query: 222 PGPS--TVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASS 279
PGP + + Q E +L+S +PG+ + +S S + S+SS
Sbjct: 462 PGPVGLALPYAIPARGRSAFQEEDFPALVSSVPKPGT--------APTSLVSAWNSSSSS 513
Query: 280 RLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSG 339
+ A P S+ + + Q + AG+ G + P P + ++ G +
Sbjct: 514 KKVAQPPLSAQATGSGQP------TRKAGKGSRGGRKGGP-PFTQEEEEDGG--PALQEL 564
Query: 340 IATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPT 399
++T S SS+L + V + ++GS P P+P TC PG + Q P
Sbjct: 565 LSTRPTGSVSSTLGLASIQPSKVGKKK-KVGS--EKPGTTLPQPPPATCPPGAL--QAPE 619
Query: 400 SLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAP 459
+ + + P ++ + P +P SA ++ G + P
Sbjct: 620 APASRAEGPVAVVVNGHTEGP----APARSAPKEPPG-------------------LPRP 656
Query: 460 QGSEATLPGPAPGEPWEAGG---PHAGPPPAFFSACPVCGGLKVNPPP 504
GS P P P E + A G P PPP FSA + G PPP
Sbjct: 657 LGS---FPCPTPQEDFPALGGPCPPRMPPPPGFSAVVLLKGTPPPPPP 701
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 39.7 bits (91), Expect = 0.006
Identities = 64/269 (23%), Positives = 88/269 (32%), Gaps = 52/269 (19%)
Query: 249 SHAGRPGSGGDDRS--LSSSSSEASHLDVSASSRLTAWPEQSSSS-----------ASTS 295
S G G+DR LS S+ L++S + P S+S + S
Sbjct: 361 SQGDEAGGHGEDRPEPLSPKESKKRKLELSRREQPPTEPGPQSASEVEKIALNLEGCALS 420
Query: 296 QEGPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSY 355
Q R + G+ A +P +PL R +V ++ D G
Sbjct: 421 QGSLRTGTQEVGGQDPGEAVQPCRQPLGARVADKVRKRRKVDEG---------------- 464
Query: 356 AGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAP 415
AG S V G +L AG+P PS G E V +P
Sbjct: 465 AGDSAAV-----ASGGAQTLALAGSPAPSGHP-KAGHSENGVEEDTEGRTGPKEGTPGSP 518
Query: 416 RDHSPPSQGSPGNSAARDSGGQTS------------AGCPSGWLGTRRRGLVMEAPQGSE 463
+ PS P +S +T A PS G R G + P S
Sbjct: 519 SETPGPSPAGPAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPRPAGPAGDEPAESP 578
Query: 464 ATLPGPAPG-----EPWEAGGPHAGPPPA 487
+ PGP+P EP E+ GP PA
Sbjct: 579 SETPGPSPAGPTRDEPAESPSETPGPRPA 607
>gi|5730059 fibroblast growth factor receptor substrate 3 [Homo
sapiens]
Length = 492
Score = 39.7 bits (91), Expect = 0.006
Identities = 64/239 (26%), Positives = 91/239 (38%), Gaps = 36/239 (15%)
Query: 113 RFHVTVAPGTKLESGPATLHLCNDVLVLARDIPPAVTGQWKLSDLRRYGAVPSGFIFEGG 172
+F VT +E G + L LVL AV +W LRRYG + F FE G
Sbjct: 20 KFKVTNVDDEGVELGSGVMELTQSELVLHLHRREAV--RWPYLCLRRYGYDSNLFSFESG 77
Query: 173 TRCGYWAGVFFLSSAEGEQISFLFDCIVR--GISPTKGPFGLRPVLPDPSPPGPSTVEER 230
RC G+F + E+I L +++ I+ + P ++ S P E
Sbjct: 78 RRCQTGQGIFAFKCSRAEEIFNLLQDLMQCNSINVMEEPV----IITRNSHP----AELD 129
Query: 231 VAQEALETLQLEKRLSLLSHAGRPGSG---GDDRSLSSSSSEASHLDVSASSRLTAWPEQ 287
+ + L +S S+ G PG G R LS+SS L ++ L A EQ
Sbjct: 130 LPRAPQPPNALGYTVSSFSN-GCPGEGPRFSAPRRLSTSSLRHPSLGEESTHALIAPDEQ 188
Query: 288 SSSSASTS----------------QEGPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEV 330
S + +T EG P QA G R P L+P Q++ V
Sbjct: 189 SHTYVNTPASEDDHRRGRHCLQPLPEGQAPFLPQARGP----DQRDPQVFLQPGQVKFV 243
>gi|171906567 peripheral benzodiazepine receptor-associated protein
1 isoform b [Homo sapiens]
Length = 1797
Score = 39.7 bits (91), Expect = 0.006
Identities = 74/284 (26%), Positives = 100/284 (35%), Gaps = 65/284 (22%)
Query: 224 PSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSRLTA 283
PS ERV+ + L T L L+ LSH SS E S L V
Sbjct: 651 PSNFVERVSDDDLLT-SLPPELADLSH--------------SSGPELSFLSVGGGG---- 691
Query: 284 WPEQSSSSASTSQEGPRPAAAQAAGEAMV-----GASRPPPKPLRPRQLQEVGRQSSS-- 336
S +S + PRP A E + G PP P PR+L + + + S
Sbjct: 692 --SSSGGQSSVGRSQPRPEEEDAGDELSLSPSPEGLGEPPAVPY-PRRLVVLKQLAHSVV 748
Query: 337 -------DSGIATGSHSSYSSSLSSYAG---------SSLDVWRATDELGSLLSLPAAGA 380
+ G H + L G +LD+W + S+ +L + G+
Sbjct: 749 LAWEPPPEQVELHGFHICVNGELRQALGPGAPPKAVLENLDLWAGPLHI-SVQALTSRGS 807
Query: 381 PEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNS----AARDSGG 436
+P C G VP+ LR H T S + PGNS A +G
Sbjct: 808 SDPLRCCLAVGARAGVVPSQLRVHRLTATSAEIT---------WVPGNSNLAHAIYLNGE 858
Query: 437 QTSAGCPSGWLGT---RRRGLVMEAPQGSEATLPGPAPGEP-WE 476
+ PS + T R G +A EA LP P EP WE
Sbjct: 859 ECPPASPSTYWATFCHLRPGTPYQAQ--VEAQLPPQGPWEPGWE 900
>gi|171906559 peripheral benzodiazepine receptor-associated protein
1 isoform a [Homo sapiens]
Length = 1857
Score = 39.7 bits (91), Expect = 0.006
Identities = 74/284 (26%), Positives = 100/284 (35%), Gaps = 65/284 (22%)
Query: 224 PSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSRLTA 283
PS ERV+ + L T L L+ LSH SS E S L V
Sbjct: 711 PSNFVERVSDDDLLT-SLPPELADLSH--------------SSGPELSFLSVGGGG---- 751
Query: 284 WPEQSSSSASTSQEGPRPAAAQAAGEAMV-----GASRPPPKPLRPRQLQEVGRQSSS-- 336
S +S + PRP A E + G PP P PR+L + + + S
Sbjct: 752 --SSSGGQSSVGRSQPRPEEEDAGDELSLSPSPEGLGEPPAVPY-PRRLVVLKQLAHSVV 808
Query: 337 -------DSGIATGSHSSYSSSLSSYAG---------SSLDVWRATDELGSLLSLPAAGA 380
+ G H + L G +LD+W + S+ +L + G+
Sbjct: 809 LAWEPPPEQVELHGFHICVNGELRQALGPGAPPKAVLENLDLWAGPLHI-SVQALTSRGS 867
Query: 381 PEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNS----AARDSGG 436
+P C G VP+ LR H T S + PGNS A +G
Sbjct: 868 SDPLRCCLAVGARAGVVPSQLRVHRLTATSAEIT---------WVPGNSNLAHAIYLNGE 918
Query: 437 QTSAGCPSGWLGT---RRRGLVMEAPQGSEATLPGPAPGEP-WE 476
+ PS + T R G +A EA LP P EP WE
Sbjct: 919 ECPPASPSTYWATFCHLRPGTPYQAQ--VEAQLPPQGPWEPGWE 960
>gi|239753407 PREDICTED: hypothetical protein [Homo sapiens]
Length = 182
Score = 39.3 bits (90), Expect = 0.008
Identities = 41/158 (25%), Positives = 56/158 (35%), Gaps = 10/158 (6%)
Query: 285 PEQSSSSASTSQEGPRPAAAQAAG-----EAMVGASRPPPKPLRPRQLQEVGRQSSSDSG 339
P ++++A+ G P AA+ +G A PPP PL P G SS G
Sbjct: 4 PPATAATAAGGATGGGPQAARRSGVQGGQRNSTSARAPPPPPLAPSSSSSSGSSGSSGGG 63
Query: 340 IATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPT 399
GS S+ +L S RA++ G A A EP P + P
Sbjct: 64 ---GSGSAGQPTLGSMLAVGSAARRASERAGGRAGGTALRAREPPPPLLPPPSPPQPGPK 120
Query: 400 SLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQ 437
+ P L L PP +P R GG+
Sbjct: 121 GPASPRPLPSPLPLLETTPFPPD--TPSRRQDRRGGGE 156
Score = 33.1 bits (74), Expect = 0.61
Identities = 25/88 (28%), Positives = 33/88 (37%), Gaps = 15/88 (17%)
Query: 415 PRDHSPPSQGSPGNSAARDSGGQTSAGCP---------------SGWLGTRRRGLVMEAP 459
P +P S S G+S + GG SAG P S G R G + A
Sbjct: 43 PPPLAPSSSSSSGSSGSSGGGGSGSAGQPTLGSMLAVGSAARRASERAGGRAGGTALRAR 102
Query: 460 QGSEATLPGPAPGEPWEAGGPHAGPPPA 487
+ LP P+P +P G P P+
Sbjct: 103 EPPPPLLPPPSPPQPGPKGPASPRPLPS 130
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 39.3 bits (90), Expect = 0.008
Identities = 77/301 (25%), Positives = 102/301 (33%), Gaps = 54/301 (17%)
Query: 207 KGPFGLRPVLPDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSS 266
+ P P P P P P+T V A+ A P SL+S
Sbjct: 1581 ESPLTPGPPHPLPDTPAPATPLPPVPPPAVA-------------AAPPTLDSTASSLTSY 1627
Query: 267 SSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPRQ 326
SE + L AS A P + P PAA Q P P P
Sbjct: 1628 DSEVATLTQGAS----AAPGDPHPPGPPAPAAPAPAAPQPG---------PDPPPGTDSG 1674
Query: 327 LQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSS--------LDVWRATDELGSLLSLPAA 378
++EV +SSSD + T S +S SSLS+ G S V + L + ++
Sbjct: 1675 IEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDG 1734
Query: 379 GAPEPSLCTCLPGTVEYQVPTSLRAH-YDTPRSLCLAP----RDHSPPSQ--------GS 425
A S P + P+ LR L P RD P+ G+
Sbjct: 1735 QAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGT 1794
Query: 426 PGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEAPQGSEATLPGPAPGEPWEAGGPHAGPP 485
G A R G +AG G + V P + ++LP PWE G GPP
Sbjct: 1795 DGLLALRACSGPPTAGVAGGPVAVEPE--VPPVPLPTASSLPRKL--LPWEEG---PGPP 1847
Query: 486 P 486
P
Sbjct: 1848 P 1848
Score = 32.7 bits (73), Expect = 0.79
Identities = 72/323 (22%), Positives = 103/323 (31%), Gaps = 79/323 (24%)
Query: 202 GISPTKGPFGLRPVLPDPSP-------PGPSTVE----------ERVAQEALETLQLEKR 244
G SP+ P + PV P PSP GP+T++ +E + +R
Sbjct: 1195 GSSPSPAP-AMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRR 1253
Query: 245 LSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSAS---SRLTAWP----EQSSSSASTSQE 297
+L G D L + ++ L S S +A P E + S A
Sbjct: 1254 STLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGY 1313
Query: 298 GPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAG 357
G A G + S PP+PL L +S G+A +
Sbjct: 1314 GAGSRAYGGGGGSSAFTSFLPPRPL-VHPLTGKALDPASPLGLALAARE----------- 1361
Query: 358 SSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRD 417
RA E S GAP+P P + Y+ P H+ +P
Sbjct: 1362 ------RALKE-----SSEGGGAPQPPP---RPPSPRYEAPPPTPHHH--------SPHA 1399
Query: 418 HSPPSQ----GSPGNSAARDSGGQTSAGCPSGWLGTR----RRGLVMEAPQ--------- 460
H P SP + A R+ G + G L RR L+ P
Sbjct: 1400 HHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLL 1459
Query: 461 ---GSEATLPGPAPGEPWEAGGP 480
G+E P P +PW + P
Sbjct: 1460 LQLGTEPPAPHPGVSKPWRSAAP 1482
>gi|110556644 zinc finger protein, multitype 1 [Homo sapiens]
Length = 1006
Score = 38.9 bits (89), Expect = 0.011
Identities = 89/345 (25%), Positives = 116/345 (33%), Gaps = 63/345 (18%)
Query: 205 PTKGPFGLRPVLPDP--SPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRS 262
P + P G +P PD S PGP EE A R S S + PGS DD
Sbjct: 621 PARAPPG-QPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQS--PGSSVDDAE 677
Query: 263 LSSSSSEASHLDVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPK-P 321
S + ++ S T + AS PR AA P P P
Sbjct: 678 DDPSRTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAP 737
Query: 322 LRPR------QLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATD-------E 368
+R R +L G G A S S S +G L R+ +
Sbjct: 738 VRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGS-GSGSGPGLAPARSPGPAADGPID 796
Query: 369 LGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGN 428
L P GAP P+L +Y T+ R + + + LA + +S P+ PG
Sbjct: 797 LSKKPRRPLPGAPAPALA-------DYHECTACRVSFHSLEAY-LAHKKYSCPAAPPPG- 847
Query: 429 SAARDSGGQTSAGCP--------SGWLGTRRR---GLVMEAP---QGSEATLP---GPAP 471
+ G +A CP G L R GL++ AP G EA P GP+P
Sbjct: 848 -----ALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSP 902
Query: 472 GE------------PWEAGGPHAGPPPAFFSACPVCGGLKVNPPP 504
P + GP PP P V PPP
Sbjct: 903 APAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPP 947
>gi|83367077 mucin 16 [Homo sapiens]
Length = 14507
Score = 38.5 bits (88), Expect = 0.014
Identities = 51/224 (22%), Positives = 92/224 (41%), Gaps = 31/224 (13%)
Query: 203 ISPTKGPFGLRPVLPDPSPPGPSTVEERVAQE-ALETLQLEKRLSLL------SHAGRPG 255
+SP P+ + S G S V + + A++ ++ E SL+ S + + G
Sbjct: 6319 VSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIFRLRETSTSQKIG 6378
Query: 256 SGGD-----DRSLSSSSSEASHLDVSASSRL----TAWPEQSSSSASTSQEGPRPAAAQA 306
S D D++ +++++E S ++++SSR T P S +++ S A
Sbjct: 6379 SSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLT 6438
Query: 307 AGEAMVGASRPPPKPLRPR---------QLQEVGRQSSSDSGIATGSHSSYSSSLSSY-A 356
E A++ P + + G S+ G + S+ +S + Y +
Sbjct: 6439 KSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYIS 6498
Query: 357 GSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTS 400
G+S T SLLSLPA +P P +P T+ P+S
Sbjct: 6499 GTSPPSVEKTSSSSSLLSLPAITSPSP-----VPTTLPESRPSS 6537
Score = 30.8 bits (68), Expect = 3.0
Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 28/158 (17%)
Query: 264 SSSSSEASHLDVSASSR--------LTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGAS 315
+ +++E S +V++SSR LT PE +S T P + + E M+
Sbjct: 8147 TGATAEVSRTEVTSSSRTSISGFAQLTVSPE---TSTETITRLPTSSIMTESAEMMIKTQ 8203
Query: 316 RPPPKPLRPRQLQEVGRQSSSDSGIATGS-------HSSYSSSLSSYAGSSLDVWRA--- 365
PP P V S++ + + T S HS ++ +S G L W +
Sbjct: 8204 TDPPGST-PESTHTVDI-STTPNWVETHSTVTQRFSHSEMTTLVSRSPGDML--WPSQSS 8259
Query: 366 ---TDELGSLLSLPAAGAPEPSLCTCLPGTVEYQVPTS 400
T SLLSLPA +P P T + +P +
Sbjct: 8260 VEETSSASSLLSLPATTSPSPVSSTLVEDFPSASLPVT 8297
>gi|169162742 PREDICTED: hypothetical protein [Homo sapiens]
Length = 382
Score = 38.5 bits (88), Expect = 0.014
Identities = 40/133 (30%), Positives = 57/133 (42%), Gaps = 11/133 (8%)
Query: 214 PVLPDPSPPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHL 273
P P P+PP ++V+ R + L+ + + L G G GG D SL +
Sbjct: 63 PACP-PTPPAKASVQPRHPARYISLLRYSEAAAPLPRGGG-GRGGQDISLRARRGGTRTG 120
Query: 274 DVSASSRLTAWPEQSSSSASTSQEGPRPAAAQAAGEAMV-GASRPPPKPLRPRQLQEVGR 332
D A LT S GP AA AA + + G +P P PL + QE GR
Sbjct: 121 DRGAE--LTR-----PQSLLARGLGPNWLAAAAANQGLGRGRDQPRPGPLPSLRAQEAGR 173
Query: 333 QSSSDSGI-ATGS 344
+ ++ G+ TGS
Sbjct: 174 RGNAVGGVTGTGS 186
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 38.5 bits (88), Expect = 0.014
Identities = 61/275 (22%), Positives = 96/275 (34%), Gaps = 36/275 (13%)
Query: 221 PPGPSTVEERVAQEALETLQLEKRLSLLSHAGRPGSGGDDRSLSSSSSEASHLDVSASSR 280
PP P + + TL+ S + G+P SGG R ++ H+
Sbjct: 906 PPNPPAQGDGTSLSPNYTLE-----STSGNDGKPVSGGGGRGRGRRKRDSGHVSPG---- 956
Query: 281 LTAWPEQSSSSASTSQEGPRPAAAQAAGEAMVGASRPPPKPLRPRQLQEVGRQSSSDSGI 340
T + + S++ S G P QA+G A VG S+ ++
Sbjct: 957 -TFFDKYSAAPDSGGAPGVSPGQQQASGAA-------------------VGGSSAGETRG 996
Query: 341 ATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGAPEPSLCTCLPGTV--EYQVP 398
A H +S S G+ L + D +GSL + + P++ V Y
Sbjct: 997 APTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANE 1056
Query: 399 TSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGGQTSAGCPSGWLGTRRRGLVMEA 458
+ + D P++L A R SP GSP G+ P LG G++ +
Sbjct: 1057 DEVSSSSDNPQALVKASR--SPLVTGSPKLPPRGVGAGEHGPKAPPPALGL---GIMSNS 1111
Query: 459 PQGSEATLPGPAPGEPWEAGGPHAGPPPAFFSACP 493
++ G PG P G P + A P
Sbjct: 1112 TSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPP 1146
Score = 30.8 bits (68), Expect = 3.0
Identities = 59/237 (24%), Positives = 74/237 (31%), Gaps = 43/237 (18%)
Query: 231 VAQEALETLQLEKRLSLLSHAGRPGS--------GGDDRSLSSSSSEASHLDVSASSRLT 282
+ Q A Q R L+ G PG GG L+ + E A RL
Sbjct: 558 IKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAG-RLG 616
Query: 283 AWPEQSSSSASTSQ--EGPRPAAAQAAGEAMVGAS------------RPPPKP-----LR 323
+ +Q+ A S GP P M G+ PPP P L
Sbjct: 617 TFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLF 676
Query: 324 PRQLQEVGRQSSSDSGIATGSHSSYSSSLSSYAGSSLDVWRATDELGSLLSLPAAGA--- 380
LQE R H S G SL G+ + LP+A +
Sbjct: 677 RGPLQEPMRMPGE-------GHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERR 729
Query: 381 -PEPSLCTCLPGTVEYQVPTSLRAHYDTPRSLCLAPRDHSPPSQGSPGNSAARDSGG 436
P P T G + P TP S P +SPPS G G S+ GG
Sbjct: 730 PPPPDFATSALGG-QPGFPFGAAGRQSTPHS---GPGVNSPPSAGGGGGSSGGGGGG 782
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,075,004
Number of Sequences: 37866
Number of extensions: 1439750
Number of successful extensions: 9111
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 517
Number of HSP's that attempted gapping in prelim test: 7586
Number of HSP's gapped (non-prelim): 1845
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.