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Search of human proteins with 111074532
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106
KDa isoform 1 [Homo sapiens]
(953 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 ... 1887 0.0
gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 K... 1090 0.0
gi|188497667 trafficking protein, kinesin binding 2 [Homo sapiens] 730 0.0
gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo sap... 141 3e-33
gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo sap... 127 6e-29
gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo sap... 127 6e-29
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 69 2e-11
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 67 8e-11
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 66 2e-10
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 66 2e-10
gi|119120918 coiled-coil domain containing 64 [Homo sapiens] 64 9e-10
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 63 1e-09
gi|71061468 centromere protein E [Homo sapiens] 63 1e-09
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 62 3e-09
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 62 3e-09
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 61 4e-09
gi|157502225 Janus kinase and microtubule interacting protein 3 ... 60 7e-09
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 60 1e-08
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 60 1e-08
gi|221219020 NYD-SP11 protein [Homo sapiens] 60 1e-08
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap... 60 1e-08
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 60 1e-08
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 60 1e-08
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 60 1e-08
gi|4758648 kinesin family member 5B [Homo sapiens] 59 2e-08
gi|21735548 centrosomal protein 2 [Homo sapiens] 59 2e-08
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 59 2e-08
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 59 2e-08
gi|38044112 restin isoform b [Homo sapiens] 59 2e-08
gi|4506751 restin isoform a [Homo sapiens] 59 2e-08
>gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 1 [Homo sapiens]
Length = 953
Score = 1887 bits (4888), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT 60
MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT
Sbjct: 1 MALVFQFGQPVRAQPLPGLCHGKLIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADT 60
Query: 61 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE 120
IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE
Sbjct: 61 IYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE 120
Query: 121 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS 180
EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS
Sbjct: 121 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS 180
Query: 181 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT 240
AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT
Sbjct: 181 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT 240
Query: 241 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA 300
YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA
Sbjct: 241 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA 300
Query: 301 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS 360
CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS
Sbjct: 301 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS 360
Query: 361 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP 420
RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP
Sbjct: 361 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTP 420
Query: 421 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER 480
SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER
Sbjct: 421 SPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDER 480
Query: 481 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP 540
SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP
Sbjct: 481 SKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTP 540
Query: 541 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI 600
TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI
Sbjct: 541 TESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGI 600
Query: 601 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK 660
LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK
Sbjct: 601 LDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHISLPRLATSTPVQHPETSAHHPGK 660
Query: 661 CMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSL 720
CMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSL
Sbjct: 661 CMSQTNSTFTFTTCRILHPSDELTRVTPSLNSAPTPACGSTSHLKSTPVATPCTPRRLSL 720
Query: 721 AESFTNTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPS 780
AESFTNTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPS
Sbjct: 721 AESFTNTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPS 780
Query: 781 TPPNSPMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSN 840
TPPNSPMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSN
Sbjct: 781 TPPNSPMQTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSN 840
Query: 841 LNLVDKVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPT 900
LNLVDKVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPT
Sbjct: 841 LNLVDKVRRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPT 900
Query: 901 VTSAIGGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTSLR 953
VTSAIGGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTSLR
Sbjct: 901 VTSAIGGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTSLR 953
>gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 2 [Homo sapiens]
Length = 686
Score = 1090 bits (2819), Expect = 0.0
Identities = 558/559 (99%), Positives = 559/559 (100%)
Query: 96 LLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVE 155
+LCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVE
Sbjct: 38 VLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVE 97
Query: 156 HIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQK 215
HIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQK
Sbjct: 98 HIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQK 157
Query: 216 KLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTE 275
KLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTE
Sbjct: 158 KLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTE 217
Query: 276 DAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAE 335
DAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAE
Sbjct: 218 DAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAE 277
Query: 336 CMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPD 395
CMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPD
Sbjct: 278 CMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPD 337
Query: 396 ITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIG 455
ITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIG
Sbjct: 338 ITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIG 397
Query: 456 NVVLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRRENYLSERRF 515
NVVLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRRENYLSERRF
Sbjct: 398 NVVLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRRENYLSERRF 457
Query: 516 FEEEQERKLQELAEKGELRSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQ 575
FEEEQERKLQELAEKGELRSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQ
Sbjct: 458 FEEEQERKLQELAEKGELRSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQ 517
Query: 576 IVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGD 635
IVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGD
Sbjct: 518 IVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGD 577
Query: 636 HISLPRLATSTPVQHPETS 654
HISLPRLATSTPVQHPETS
Sbjct: 578 HISLPRLATSTPVQHPETS 596
>gi|188497667 trafficking protein, kinesin binding 2 [Homo sapiens]
Length = 914
Score = 730 bits (1885), Expect = 0.0
Identities = 450/931 (48%), Positives = 588/931 (63%), Gaps = 79/931 (8%)
Query: 31 DVCNSTDLPEVEIISLLEEQLPHYKLRADTIYGYDHDDWLHTPLISPDANIDLTTEQIEE 90
DVC++ DLPEVE++SLLEEQLP Y+L+ DT++ Y++ DW +P A+ L+ EE
Sbjct: 31 DVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEE 90
Query: 91 TLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELL 150
T +Y +L +RV QMTKTYNDID VT LL E++RDLELAARIGQ+LLK+N L+E+NE L
Sbjct: 91 TFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESL 150
Query: 151 EEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHL 210
EEQ+ ++V+QL+HEL KDELL+ + A+EESE +S CSTPL+ NES S Q L
Sbjct: 151 EEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQL 210
Query: 211 DSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEEL 270
+ LQ+KLK+LEEEN+ LRS+A +KTET+TYEEKEQQLV+DCVKELR+ N Q++ ++EEL
Sbjct: 211 EMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEEL 270
Query: 271 AKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELE 330
+ K+++ R QEE++ LLSQIVDLQ K K +E EEL HL A+KDAQRQLT EL EL+
Sbjct: 271 SGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQ 330
Query: 331 DKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEE 390
D+ EC+ MLHE+QEE+K LR+++ P S G F +SLAAEIEGTMRK+L L+E
Sbjct: 331 DRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDE 390
Query: 391 AES--PDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSS 448
S QKRVF+TVR N + P+ + IPGSN+SS + + P S
Sbjct: 391 ESSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVI------MTAKPFES 444
Query: 449 FYGSDIGNVVLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRREN 508
+L+ ++S E A S+K G PG G DL TAL RLSLRR+N
Sbjct: 445 GLQQTEDKSLLNQGSSS----EEVAG-----SSQKMGQPGPSGDSDLATALHRLSLRRQN 495
Query: 509 YLSERRFFEEEQERKLQELAEKGELRSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRS 568
YLSE++FF EE +RK+Q LA++ E SG +TPTES+ SL T SE T S S R
Sbjct: 496 YLSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESLASLCTTQ--SEITDLSSAS-CLRG 552
Query: 569 YLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDF 628
++PEKLQIVKPLEGS TL+HWQQLAQP+LG ILDPRPGV+TKGF L D +Y ++D
Sbjct: 553 FMPEKLQIVKPLEGSQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLPG--DAIYHISDL 610
Query: 629 EEDDTGD---HISLP-----RLATSTPVQ----HPETSA--------HHPGKCMSQTNST 668
EED+ + P +L+TS PV P TSA +PGKC+S TNST
Sbjct: 611 EEDEEEGITFQVQQPLEVEEKLSTSKPVTGIFLPPITSAGGPVTVATANPGKCLSCTNST 670
Query: 669 FTFTTCRILHPSDELTRVTPSLNSAPTPACGST-SHLKSTPVATPCTPRRLSLAESFTNT 727
FTFTTCRILHPSD +T+VTPS + P+ +CGS+ S +T V +P RLS+ ES TN
Sbjct: 671 FTFTTCRILHPSD-ITQVTPS-SGFPSLSCGSSGSSSSNTAVNSPALSYRLSIGESITNR 728
Query: 728 RESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPSTPPNSPM 787
R+STTT S+++ L LL+ERGISA VY + + PK IPSTPPNSP
Sbjct: 729 RDSTTTFSSTMSLAKLLQERGISAKVYHSPISENPLQP------LPKSLAIPSTPPNSPS 782
Query: 788 QTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSNLNLVDKV 847
+P SP FE + +NFLAS+PA + L+E+ +R S + DV +NLVD++
Sbjct: 783 HSPCPSPLPFEPRVHLS--ENFLASRPAETFLQEM--YGLRPSRNPPDVGQLKMNLVDRL 838
Query: 848 RRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPTVTSAIGG 907
+R G+A+VV + A +E GP P A+ G
Sbjct: 839 KRLGIARVVKNPGAQENGRCQEAE---IGPQKPDSAVYLN------------------SG 877
Query: 908 LQLNSGIRRNRSFPTMVGSSMQMKAPVTLTS 938
L G+RRN+S P ++GS APV +S
Sbjct: 878 SSLLGGLRRNQSLPVIMGS---FAAPVCTSS 905
>gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo
sapiens]
Length = 619
Score = 141 bits (356), Expect = 3e-33
Identities = 98/282 (34%), Positives = 152/282 (53%), Gaps = 49/282 (17%)
Query: 121 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS 180
++ERDL AARIGQSL+K+N L E N LE + +EE+ LRH+++++DELLQ Y+
Sbjct: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
Query: 181 AAEESEPES-------------------------VCSTPLKRNESSSSVQNYF-HLDSLQ 214
+ EE E E C P ++ + Q++ L++LQ
Sbjct: 259 SDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQ 318
Query: 215 KKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKT 274
+KL+ LEEEN LR EASQL T E++EQ L+ +CV++ +A+ Q+A +SE L +
Sbjct: 319 EKLRLLEEENHQLREEASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLVLRL 374
Query: 275 EDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAE--LRELEDK 332
E+ RQQ+E+ L +Q++ LQ++ + E E+L + L + K+ Q QL E L ++
Sbjct: 375 ENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEEETLPGFQET 434
Query: 333 YAECMEMLHEAQEELKNL---------RNKTMP--NTTSRRY 363
AE E + L+ + RN MP +T+S RY
Sbjct: 435 LAE------ELRTSLRRMISDPVYFMERNYEMPRGDTSSLRY 470
>gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo
sapiens]
Length = 594
Score = 127 bits (318), Expect = 6e-29
Identities = 76/205 (37%), Positives = 119/205 (58%), Gaps = 30/205 (14%)
Query: 121 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS 180
++ERDL AARIGQSL+K+N L E N LE + +EE+ LRH+++++DELLQ Y+
Sbjct: 199 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 258
Query: 181 AAEESEPES-------------------------VCSTPLKRNESSSSVQNYF-HLDSLQ 214
+ EE E E C P ++ + Q++ L++LQ
Sbjct: 259 SDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQ 318
Query: 215 KKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKT 274
+KL+ LEEEN LR EASQL T E++EQ L+ +CV++ +A+ Q+A +SE L +
Sbjct: 319 EKLRLLEEENHQLREEASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLVLRL 374
Query: 275 EDAARQQEEITHLLSQIVDLQKKAK 299
E+ RQQ+E+ L +Q++ LQ++ +
Sbjct: 375 ENYERQQQEVARLQAQVLKLQQRCR 399
>gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo
sapiens]
Length = 602
Score = 127 bits (318), Expect = 6e-29
Identities = 76/205 (37%), Positives = 119/205 (58%), Gaps = 30/205 (14%)
Query: 121 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS 180
++ERDL AARIGQSL+K+N L E N LE + +EE+ LRH+++++DELLQ Y+
Sbjct: 207 QRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQLYSD 266
Query: 181 AAEESEPES-------------------------VCSTPLKRNESSSSVQNYF-HLDSLQ 214
+ EE E E C P ++ + Q++ L++LQ
Sbjct: 267 SDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLEALQ 326
Query: 215 KKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKT 274
+KL+ LEEEN LR EASQL T E++EQ L+ +CV++ +A+ Q+A +SE L +
Sbjct: 327 EKLRLLEEENHQLREEASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLVLRL 382
Query: 275 EDAARQQEEITHLLSQIVDLQKKAK 299
E+ RQQ+E+ L +Q++ LQ++ +
Sbjct: 383 ENYERQQQEVARLQAQVLKLQQRCR 407
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 68.9 bits (167), Expect = 2e-11
Identities = 68/310 (21%), Positives = 129/310 (41%), Gaps = 46/310 (14%)
Query: 63 GYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEK 122
G + + LH + D+ L ++E TLK L E I A+ LEE
Sbjct: 936 GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEE---------KIAALEARLEE- 985
Query: 123 ERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIR-----------------EEVSQLR 165
+ Q L ++ KT+ + E L+++ + R E R
Sbjct: 986 ------STNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTR 1039
Query: 166 HELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENV 225
L +KD L++ + A + T LK+ E+ ++ + +LQ++ L+E+N
Sbjct: 1040 ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNN-NLQAQILALQRQTVSLQEQNT 1098
Query: 226 VLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEIT 285
L+++ ++L+ E T + L+N N Q+ L + E +++E++
Sbjct: 1099 TLQTQNAKLQVENSTLNSQSTSLMNQ--------NAQLLIQQSSLENENESVIKEREDLK 1150
Query: 286 HLLSQIVDLQKKAKAC----AVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLH 341
L ++ +K + A E E L+ G K A + L E R+LED+Y + ++
Sbjct: 1151 SLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKG 1210
Query: 342 EAQEELKNLR 351
+ ++ K L+
Sbjct: 1211 QLEDLEKMLK 1220
Score = 57.0 bits (136), Expect = 8e-08
Identities = 84/416 (20%), Positives = 190/416 (45%), Gaps = 54/416 (12%)
Query: 81 IDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKN 140
+D+ +++++TL+ +++ Q+ D++ + L++ +L+++++ + L K+N
Sbjct: 761 LDIENQRLQKTLEN---SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKEN 817
Query: 141 KTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES 200
K+L + LE+ + + +E +LR + +KD L E +V L++
Sbjct: 818 KSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL----------EENNVKIGNLEKENK 867
Query: 201 SSSVQNYFHLDSLQKKLKDLEEENVVLRSEAS-QLKT-----ETITYEEKEQQLVNDCVK 254
+ S + + +S +LK+LE+EN L A+ +KT E + E+ + Q +N+ ++
Sbjct: 868 TLSKEIGIYKESC-VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Query: 255 ELRDANVQIASISEEL---AKKTEDAARQ--QEEITHLLSQIVDLQKKAKACAVENEELV 309
+L +I E L + T+D+ + + ++ L + +++ K+ K A+E
Sbjct: 927 KLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEI-KEEKIAALE----- 980
Query: 310 QHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYH----- 364
L + + +QL EL+ ++ Y E L + Q+E + +++ + ++
Sbjct: 981 ARLEESTNYNQQLRQELKTVKKNY----EALKQRQDEERMVQSSPPISGEDNKWERESQE 1036
Query: 365 -SLGLFPMDSLAAEIE---GTMRKE-----LQLEEAESPDITHQKRVFETVRNINQVVKQ 415
+ L + E+E T++ E QL++ E+ + Q ++ R + +Q
Sbjct: 1037 TTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQ 1096
Query: 416 RSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETE 471
+ T N ++S +NS +S ++ I L+N+ S+I E E
Sbjct: 1097 NT-TLQTQNAKLQVENSTLNSQSTSLMNQNAQLL----IQQSSLENENESVIKERE 1147
Score = 55.8 bits (133), Expect = 2e-07
Identities = 85/371 (22%), Positives = 166/371 (44%), Gaps = 53/371 (14%)
Query: 70 LHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQ-MTKTYNDIDAVTRL-LEEKERDLE 127
L L+ A ++ T E + E + + E+ + + +T + + +++ E + +D+E
Sbjct: 527 LSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Query: 128 LAARIGQSLLKKNKTLTERNEL----LEEQVEHIRE------EVSQLRHELSMKDELLQF 177
+I +K+ + + E +++++EH +E E+ H L ++ELLQ
Sbjct: 587 KENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQK 646
Query: 178 YTS---------AAEESEPESVCSTPLKRNESSSSVQNY-FHLDSLQKKLKDLEEENVVL 227
+ A E E + K ++ S +N F L+SL+K+ L+EEN+ L
Sbjct: 647 KITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLEL 706
Query: 228 RSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELA---KKTE--------- 275
R LK ++ + + QL N KEL Q+ E L KKTE
Sbjct: 707 RRNVESLKCASM--KMAQLQLEN---KELESEKEQLKKGLELLKASFKKTERLEVSYQGL 761
Query: 276 --DAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQR---QLTAELRELE 330
+ R Q+ + + +I L+ + + +EN+ L ++L K + + QL E + LE
Sbjct: 762 DIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLE 821
Query: 331 DKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMD----SLAAEI----EGTM 382
+ ++ + + ++E K LR + T+ +++ + ++ +L+ EI E +
Sbjct: 822 QETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCV 881
Query: 383 R-KELQLEEAE 392
R KEL+ E E
Sbjct: 882 RLKELEKENKE 892
Score = 49.3 bits (116), Expect = 2e-05
Identities = 52/255 (20%), Positives = 114/255 (44%), Gaps = 19/255 (7%)
Query: 120 EEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQ--- 176
+E+ D+E + L + N+ L E +LE+Q+E R +L HEL ++ L+
Sbjct: 333 KERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL-HELEKENLQLKAKL 391
Query: 177 --------FYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLR 228
EE E++ ++ S+ + L+ + + + E L
Sbjct: 392 HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLG 451
Query: 229 SEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLL 288
E ++L + + E E Q + V+ELR + + ++ K ++ R +++ L
Sbjct: 452 HEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE 511
Query: 289 SQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAE-LRELEDKYAECMEMLHE-AQEE 346
++IV ++ + C +++L++ + AQ + T E LRE ++ + +E +E +
Sbjct: 512 NEIVQEKQSLQNCQNLSKDLMK-----EKAQLEKTIETLRENSERQIKILEQENEHLNQT 566
Query: 347 LKNLRNKTMPNTTSR 361
+ +LR ++ + +R
Sbjct: 567 VSSLRQRSQISAEAR 581
Score = 40.8 bits (94), Expect = 0.006
Identities = 79/329 (24%), Positives = 131/329 (39%), Gaps = 82/329 (24%)
Query: 137 LKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTP-L 195
L KN L L++E+ EH S+ ELS + + L F A+ S +S C +P +
Sbjct: 189 LLKNMAL-HLKRLIDERDEH-----SETIIELSEERDGLHFLPHAS--SSAQSPCGSPGM 240
Query: 196 KRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKE 255
KR ES + L + K++ L +E EEK +QL+ DC +E
Sbjct: 241 KRTESRQHLS--VELADAKAKIRRLRQE-----------------LEEKTEQLL-DCKQE 280
Query: 256 LRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAA 315
L +++ R Q+E +LLS A++ + +EL
Sbjct: 281 LEQMEIELK--------------RLQQENMNLLSD-------ARSARMYRDEL------- 312
Query: 316 KDAQRQLTAELRELEDKYAECMEMLHEAQ------EELKN-----LRNKTM-------PN 357
DA R+ + +LE + + E LH+ + EELK L KTM
Sbjct: 313 -DALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTR 371
Query: 358 TTSRRYHSLGLFPMDSLAAEIEGTMRKEL---QLEEAESPDIT---HQKRVFETVRNINQ 411
S + H L + A + M +++ ++EE ++T QK+ + ++
Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGW 431
Query: 412 VVKQRSLTPSPMNIPGSNQSSAMNSLLSS 440
++Q S T P + +N L SS
Sbjct: 432 ELEQISRTSELSEAPQKSLGHEVNELTSS 460
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 67.0 bits (162), Expect = 8e-11
Identities = 92/375 (24%), Positives = 159/375 (42%), Gaps = 66/375 (17%)
Query: 70 LHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELA 129
L T L + + T Q++E L+ L A+ + + Y I +T L E + ++E
Sbjct: 1065 LETELQNAHGELKSTLRQLQE-LRDVLQKAQL--SLEEKYTTIKDLTAELRECKMEIEDK 1121
Query: 130 ARIGQSLLKKNKTLTERNELLEE---QVEHIREEVSQLRHELSMKDELLQFYTSAAEESE 186
Q LL+ ++ L ERN L++ QV H+ + + R E+ K L+ E+SE
Sbjct: 1122 K---QELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLE---GTLEKSE 1175
Query: 187 PESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVL---RSEASQLKTET----- 238
L+ E + +++ D LQ + L E+ ++ E SQLK E
Sbjct: 1176 --------LELKECNKQIESLN--DKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQ 1225
Query: 239 ------ITYEEKEQQLVN------DCVKELRDANVQIASISEELAKKTEDAARQQEEITH 286
+E+EQ + D +ELR Q+ + ELA+ + Q EI
Sbjct: 1226 RMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIER 1285
Query: 287 LLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEE 346
L S++ D+++ +K L + LGA+K + L A ++ K + +E L EA
Sbjct: 1286 LSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYH- 1344
Query: 347 LKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEI----EGTMRKELQLEEAESPDITHQKRV 402
M + + H+ DS + + E + +L+LEEA+
Sbjct: 1345 --------MEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQ---------- 1386
Query: 403 FETVRNINQVVKQRS 417
+TV N++Q V+ R+
Sbjct: 1387 -DTVSNLHQQVQDRN 1400
Score = 51.6 bits (122), Expect = 3e-06
Identities = 72/316 (22%), Positives = 131/316 (41%), Gaps = 39/316 (12%)
Query: 104 QMTKTYNDIDAVTRLLEEKERDLELAAR---IGQSLLKKNKTL----TERNELLEEQVEH 156
Q+ K ++ + + L+ K L+ + I Q L++ + + T RN LE+
Sbjct: 875 QLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTK 934
Query: 157 IREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNE----SSSSVQNYFHLDS 212
+ ++VS+L EL + E EE + LKR + + ++ Q +D
Sbjct: 935 LEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQ 994
Query: 213 LQKKLKDLEEENVVLR----------SEASQLKTETITYEEKEQQLVNDCVKELRDANVQ 262
+++L +E+E + L+ S+ + +T T EK+ V + K +
Sbjct: 995 YKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETE 1054
Query: 263 IASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQL 322
+ ++ + E+ L Q+ +L+ + + EE + + L
Sbjct: 1055 LTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTI-------KDL 1107
Query: 323 TAELRE----LEDKYAECMEM---LHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLA 375
TAELRE +EDK E +EM L E ELK + + R H M+
Sbjct: 1108 TAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHR---GEMEQKI 1164
Query: 376 AEIEGTMRK-ELQLEE 390
++EGT+ K EL+L+E
Sbjct: 1165 IKLEGTLEKSELELKE 1180
Score = 47.0 bits (110), Expect = 8e-05
Identities = 89/384 (23%), Positives = 149/384 (38%), Gaps = 103/384 (26%)
Query: 99 AERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTL-------TERNELLE 151
+E + Q+T++ I + LE K+ L R SL+ +N+ L ER +L +
Sbjct: 445 SEVMAQLTESRQSILKLESELENKDEIL----RDKFSLMNENRELKVRVAAQNERLDLCQ 500
Query: 152 EQVEHIREEVSQLRH---ELSMKDELLQF--YTS-------------------------- 180
+++E R E+ L +L +K EL F Y S
Sbjct: 501 QEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVIS 560
Query: 181 ------AAEESEPESVCSTPLKRNESSSSV------QNYFHLDSLQKKLKDLEEENVVLR 228
A +E+E + + + L N+ S S+ Q L SL+ + L V
Sbjct: 561 ELRIKLAIKEAEIQKLHAN-LTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVAES 619
Query: 229 SEASQLKTETITYEEKEQQLVNDCVKELRDANVQIAS------------------ISEEL 270
+ T YE++ Q+LV ++ELR +QI + I EEL
Sbjct: 620 VKDQNQHTMNKQYEKERQRLVTG-IEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEEL 678
Query: 271 AKKTEDAARQQEEITHLLSQIVDLQKKAK-------ACAVENEELVQHLGAAKDAQRQLT 323
+K ++++ + E+T SQ++ L+K+ + + A +N EL Q L + R L
Sbjct: 679 LEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLE 738
Query: 324 AELRELEDKYA---ECMEMLH--------------EAQEELKNLRNKTMPNTTSRRYHSL 366
+ +K E + +H EAQ E K+ + K T S +
Sbjct: 739 TNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDI 798
Query: 367 -----GLFPMDSLAAEIEGTMRKE 385
L +D L E +G M+KE
Sbjct: 799 ICKQHHLESLDRLLTESKGEMKKE 822
Score = 42.0 bits (97), Expect = 0.003
Identities = 53/249 (21%), Positives = 114/249 (45%), Gaps = 24/249 (9%)
Query: 115 VTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDEL 174
V LE+ + + E+ R + K+NK L ER L + ++E ++E++ QL+ E + E
Sbjct: 377 VAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEK 436
Query: 175 LQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQL 234
L+ A + SE + + + S Q+ L+S + ++ + L +E +L
Sbjct: 437 LRI--MAVKNSEVMA---------QLTESRQSILKLESELENKDEILRDKFSLMNENREL 485
Query: 235 KTETITYEEKEQQLVNDCVKELRDANVQIASISE---ELAKKTEDAARQQEEITHLLSQI 291
K E+ ++ C +E+ + V++ S+ + +L K E + + +S
Sbjct: 486 KVRVAAQNER----LDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSF 541
Query: 292 VDLQKKAKACAVENEELVQHLG---AAKDAQ-RQLTAELRELEDKYAECMEMLHEAQEEL 347
+ + + C N+ ++ L A K+A+ ++L A L ++ ++ + +++QE
Sbjct: 542 SNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANL--TANQLSQSLITCNDSQESS 599
Query: 348 KNLRNKTMP 356
K +T P
Sbjct: 600 KLSSLETEP 608
Score = 40.8 bits (94), Expect = 0.006
Identities = 66/335 (19%), Positives = 133/335 (39%), Gaps = 68/335 (20%)
Query: 70 LHTPLISPDA-NIDLTTEQIEETLKYFLLCAERV----------GQMTKTYNDIDAVTRL 118
L T LI +A N DL T ++ L+ E + +MTK + + + +
Sbjct: 646 LRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQ 705
Query: 119 LEEK----ERDLELAARIGQSLLKKNKTL--------TERNELLE----------EQVEH 156
LEEK A + Q L++KN+ + TE ++ EQ +
Sbjct: 706 LEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKE 765
Query: 157 IREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKK 216
+ +++ +L +L KD+ + + + +C HL+SL +
Sbjct: 766 MEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIIC--------------KQHHLESLDRL 811
Query: 217 LK----DLEEENV----VLRSEASQLKTETITYEEKEQQL---VNDCVKELRDANVQIAS 265
L ++++EN+ L++ +Q+ ETI + + L + V L
Sbjct: 812 LTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEK 871
Query: 266 ISEELAKKTEDAARQQEEI---THLLSQIVDLQKKAKACAVENEELVQ----HLGAAKDA 318
++L KK+E+ Q+E+ H L + + + + ++++Q G +D
Sbjct: 872 FEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDT 931
Query: 319 QRQLTAELRELEDKYAECMEMLHEAQEELKNLRNK 353
Q +L ++ +LE E + + E+L+ + K
Sbjct: 932 QTKLEKQVSKLEQ---ELQKQRESSAEKLRKMEEK 963
Score = 33.9 bits (76), Expect = 0.74
Identities = 49/225 (21%), Positives = 98/225 (43%), Gaps = 28/225 (12%)
Query: 177 FYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKT 236
F +SA + E +S+ K + ++ + H SL K + + E R++ S L++
Sbjct: 221 FSSSAPVDQEIKSLREKLNKLRQQNACLVTQNH--SLMTKFESIHFELTQSRAKVSMLES 278
Query: 237 ---ETITYEEKEQQLVNDCV------KELRDANVQIASISEELAKKTEDAARQQEEITHL 287
+ + E+Q++N K LR+A ++ + + +K + +EE L
Sbjct: 279 AQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKL 338
Query: 288 LSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEEL 347
+++ K+ K + E + + +L+ ++ + K AE +E + +A+EE+
Sbjct: 339 KVDLLEQTKQGKRAERQRNEALYN-------AEELSKAFQQYKKKVAEKLEKV-QAEEEI 390
Query: 348 --KNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEE 390
+NL N N R GL+ +E+E K QL+E
Sbjct: 391 LERNLTNCEKEN--KRLQERCGLY-----KSELEILKEKLRQLKE 428
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 65.9 bits (159), Expect = 2e-10
Identities = 55/250 (22%), Positives = 109/250 (43%), Gaps = 30/250 (12%)
Query: 123 ERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIR-----------------EEVSQLR 165
E LE + Q L ++ KT+ + E L+++ + R E R
Sbjct: 979 EARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTR 1038
Query: 166 HELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENV 225
L +KD L++ + A + T LK+ E+ ++ + +LQ++ L+E+N
Sbjct: 1039 ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNN-NLQAQILALQRQTVSLQEQNT 1097
Query: 226 VLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEIT 285
L+++ ++L+ E T + L+N N Q+ L + E +++E++
Sbjct: 1098 TLQTQNAKLQVENSTLNSQSTSLMNQ--------NAQLLIQQSSLENENESVIKEREDLK 1149
Query: 286 HLLSQIVDLQKKAKAC----AVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLH 341
L ++ +K + A E E L+ G K A + L E R+LED+Y + ++
Sbjct: 1150 SLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKG 1209
Query: 342 EAQEELKNLR 351
+ ++ K L+
Sbjct: 1210 QLEDLEKMLK 1219
Score = 57.4 bits (137), Expect = 6e-08
Identities = 82/413 (19%), Positives = 178/413 (43%), Gaps = 49/413 (11%)
Query: 81 IDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKN 140
+D+ +++++TL+ +++ Q+ D++ + L++ +L+++++ + L K+N
Sbjct: 761 LDIENQRLQKTLEN---SNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKEN 817
Query: 141 KTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNES 200
K+L + LE+ + + +E +LR + +KD L E +V L++
Sbjct: 818 KSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL----------EENNVKIGNLEKENK 867
Query: 201 SSSVQNYFHLDSLQKKLKDLEEENVVLRSEAS-------QLKTETITYEEKEQQLVNDCV 253
+ S + + +S +LK+LE+EN L A+ L+ + ++ + K QQ+ ND
Sbjct: 868 TLSKEIGIYKESC-VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNND-- 924
Query: 254 KELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVEN-EELVQHL 312
L ++ I + D + L S++ KK+ E L L
Sbjct: 925 --LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARL 982
Query: 313 GAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYH------SL 366
+ + +QL EL+ ++ Y E L + Q+E + +++ + ++ +
Sbjct: 983 EESTNYNQQLRQELKTVKKNY----EALKQRQDEERMVQSSPPISGEDNKWERESQETTR 1038
Query: 367 GLFPMDSLAAEIE---GTMRKE-----LQLEEAESPDITHQKRVFETVRNINQVVKQRSL 418
L + E+E T++ E QL++ E+ + Q ++ R + +Q +
Sbjct: 1039 ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNT- 1097
Query: 419 TPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETE 471
T N ++S +NS +S ++ I L+N+ S+I E E
Sbjct: 1098 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLL----IQQSSLENENESVIKERE 1146
Score = 55.8 bits (133), Expect = 2e-07
Identities = 85/371 (22%), Positives = 166/371 (44%), Gaps = 53/371 (14%)
Query: 70 LHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQ-MTKTYNDIDAVTRL-LEEKERDLE 127
L L+ A ++ T E + E + + E+ + + +T + + +++ E + +D+E
Sbjct: 527 LSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Query: 128 LAARIGQSLLKKNKTLTERNEL----LEEQVEHIRE------EVSQLRHELSMKDELLQF 177
+I +K+ + + E +++++EH +E E+ H L ++ELLQ
Sbjct: 587 KENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQK 646
Query: 178 YTS---------AAEESEPESVCSTPLKRNESSSSVQNY-FHLDSLQKKLKDLEEENVVL 227
+ A E E + K ++ S +N F L+SL+K+ L+EEN+ L
Sbjct: 647 KITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLEL 706
Query: 228 RSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELA---KKTE--------- 275
R LK ++ + + QL N KEL Q+ E L KKTE
Sbjct: 707 RRNVESLKCASM--KMAQLQLEN---KELESEKEQLKKGLELLKASFKKTERLEVSYQGL 761
Query: 276 --DAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQR---QLTAELRELE 330
+ R Q+ + + +I L+ + + +EN+ L ++L K + + QL E + LE
Sbjct: 762 DIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLE 821
Query: 331 DKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMD----SLAAEI----EGTM 382
+ ++ + + ++E K LR + T+ +++ + ++ +L+ EI E +
Sbjct: 822 QETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCV 881
Query: 383 R-KELQLEEAE 392
R KEL+ E E
Sbjct: 882 RLKELEKENKE 892
Score = 49.3 bits (116), Expect = 2e-05
Identities = 52/255 (20%), Positives = 114/255 (44%), Gaps = 19/255 (7%)
Query: 120 EEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQ--- 176
+E+ D+E + L + N+ L E +LE+Q+E R +L HEL ++ L+
Sbjct: 333 KERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL-HELEKENLQLKAKL 391
Query: 177 --------FYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLR 228
EE E++ ++ S+ + L+ + + + E L
Sbjct: 392 HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLG 451
Query: 229 SEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLL 288
E ++L + + E E Q + V+ELR + + ++ K ++ R +++ L
Sbjct: 452 HEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE 511
Query: 289 SQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAE-LRELEDKYAECMEMLHE-AQEE 346
++IV ++ + C +++L++ + AQ + T E LRE ++ + +E +E +
Sbjct: 512 NEIVQEKQSLQNCQNLSKDLMK-----EKAQLEKTIETLRENSERQIKILEQENEHLNQT 566
Query: 347 LKNLRNKTMPNTTSR 361
+ +LR ++ + +R
Sbjct: 567 VSSLRQRSQISAEAR 581
Score = 40.8 bits (94), Expect = 0.006
Identities = 79/329 (24%), Positives = 131/329 (39%), Gaps = 82/329 (24%)
Query: 137 LKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTP-L 195
L KN L L++E+ EH S+ ELS + + L F A+ S +S C +P +
Sbjct: 189 LLKNMAL-HLKRLIDERDEH-----SETIIELSEERDGLHFLPHAS--SSAQSPCGSPGM 240
Query: 196 KRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKE 255
KR ES + L + K++ L +E EEK +QL+ DC +E
Sbjct: 241 KRTESRQHLS--VELADAKAKIRRLRQE-----------------LEEKTEQLL-DCKQE 280
Query: 256 LRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAA 315
L +++ R Q+E +LLS A++ + +EL
Sbjct: 281 LEQMEIELK--------------RLQQENMNLLSD-------ARSARMYRDEL------- 312
Query: 316 KDAQRQLTAELRELEDKYAECMEMLHEAQ------EELKN-----LRNKTM-------PN 357
DA R+ + +LE + + E LH+ + EELK L KTM
Sbjct: 313 -DALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTR 371
Query: 358 TTSRRYHSLGLFPMDSLAAEIEGTMRKEL---QLEEAESPDIT---HQKRVFETVRNINQ 411
S + H L + A + M +++ ++EE ++T QK+ + ++
Sbjct: 372 ARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGW 431
Query: 412 VVKQRSLTPSPMNIPGSNQSSAMNSLLSS 440
++Q S T P + +N L SS
Sbjct: 432 ELEQISRTSELSEAPQKSLGHEVNELTSS 460
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 65.9 bits (159), Expect = 2e-10
Identities = 74/295 (25%), Positives = 122/295 (41%), Gaps = 35/295 (11%)
Query: 79 ANIDLTTEQIEETLKYFLLCAERV-GQMTKTYNDIDAVTRLLEEKERDLELAA-RIGQSL 136
A ++ EQ+E + LL E + G++ I A E+ D EL A ++ Q+
Sbjct: 921 AQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQ---EKASLDKELMAQKLVQAE 977
Query: 137 LKKNKTLTERNELLEEQVEHIREEV-----------SQLRHELSMKDELLQFYTSAAEES 185
+ +L E+ EE ++ ++ E +QL+ +L + E L A +E
Sbjct: 978 REAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEE 1037
Query: 186 EPESVCSTPLKRNE----SSSSVQNYFHLD-----SLQKKLKDLEEENVVLRSEASQLKT 236
E + + +R+E + S Q L +L +KL + E + K
Sbjct: 1038 LSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKR 1097
Query: 237 ETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQK 296
+ + +E+++ VN ELRD Q + E AA +E+ L Q DL K
Sbjct: 1098 DAQSRQEQDRSTVNALTSELRDLRAQ----------REEAAAAHAQEVRRLQEQARDLGK 1147
Query: 297 KAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLR 351
+ +C E EEL L +DA+ L EL E + K E E ++E LR
Sbjct: 1148 QRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELR 1202
Score = 53.9 bits (128), Expect = 7e-07
Identities = 59/281 (20%), Positives = 131/281 (46%), Gaps = 33/281 (11%)
Query: 81 IDLTTEQIEETLKYFLLCAER---------VGQMTKTYNDI-DAVTRLLEEKERDLELAA 130
++LT E + +TL+ +LC E+ Q+T I + VTR L + E + L A
Sbjct: 11 VELTLETVIQTLESSVLCQEKGLGARDLAQDAQITSLPALIREIVTRNLSQPESPVLLPA 70
Query: 131 RIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESV 190
SLL +L E N+LL++++ + + ++Q R E +DEL Y + +E E
Sbjct: 71 TEMASLL----SLQEENQLLQQELSRVEDLLAQSRAE---RDELAIKYNAVSERLEQ--- 120
Query: 191 CSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVN 250
+ L+ E + S++ + + L+EE R + + ++++ QLV
Sbjct: 121 -ALRLEPGELETQEPRGLVRQSVELR-RQLQEEQASYRRKLQAYQEG----QQRQAQLVQ 174
Query: 251 DCVKELRDANVQIASISEELAKKTEDAARQQ-------EEITHLLSQIVDLQKKAKACAV 303
++ + + + ++L +++ + +Q+ +++ L ++ + Q+++ + A
Sbjct: 175 RLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQ 234
Query: 304 ENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQ 344
N L + L A A + L+ ++R++ + + C + L +
Sbjct: 235 VNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHRE 275
Score = 52.8 bits (125), Expect = 2e-06
Identities = 99/442 (22%), Positives = 173/442 (39%), Gaps = 43/442 (9%)
Query: 115 VTRLLEEKERDLELAARIGQSLLKKNKTLTER-NELLEEQVEHIREEVSQLRHELSMKDE 173
V R +E+ +L L + + L+ + + E+ E LE+Q+ +R E SQL+ +L+
Sbjct: 782 VAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 841
Query: 174 LLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQ 233
L E++ E+ + L +L E E L EA++
Sbjct: 842 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 901
Query: 234 LKTETITYE----EKEQQLVN-DCVKELRDANVQIASISEELAKKTEDAARQQEEITH-- 286
L+ E E E ++QL + +E +A Q +++E RQQ T
Sbjct: 902 LRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEK 961
Query: 287 -------LLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEM 339
+ ++V +++A+A E+ H + QR+ A RELE + A+
Sbjct: 962 ASLDKELMAQKLVQAEREAQASL--REQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQ 1019
Query: 340 LHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQ 399
L QEEL R + S +L + L E ++ L L+E+E ++
Sbjct: 1020 LQREQEELL-ARLEAEKEELSEEIAALQQERDEGLLL-AESEKQQALSLKESEKTALS-- 1075
Query: 400 KRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSC--VSTPRSSFYGSDIGNV 457
+++ T ++ + + S +N+L S + R + V
Sbjct: 1076 EKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEV 1135
Query: 458 VLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRL-----SLRRENYLSE 512
L+ +A DLG S + +L T LR L LRRE ++
Sbjct: 1136 RR--------LQEQARDLGKQRDS------CLREAEELRTQLRLLEDARDGLRRELLEAQ 1181
Query: 513 RRFFEEEQERKLQELAEKGELR 534
R+ E ++ R++Q E GELR
Sbjct: 1182 RKLRESQEGREVQR-QEAGELR 1202
Score = 42.4 bits (98), Expect = 0.002
Identities = 65/320 (20%), Positives = 134/320 (41%), Gaps = 31/320 (9%)
Query: 108 TYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHE 167
T + + ++ +E ++RD + +R Q N +E +L ++ E ++R
Sbjct: 1081 TRHSLATISLEMERQKRDAQ--SRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRL 1138
Query: 168 LSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVL 227
+L + S E+E T L+ E + L++ Q+KL++ +E V
Sbjct: 1139 QEQARDLGKQRDSCLREAEE---LRTQLRLLEDARDGLRRELLEA-QRKLRESQEGREVQ 1194
Query: 228 RSEASQLKTETITYEEKEQQLVNDCVKELRDA---------NVQIASISEE--LAKKTED 276
R EA +L+ ++ KE++ + +ELR A ++++A+ +E LA E
Sbjct: 1195 RQEAGELR-RSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEA 1253
Query: 277 AARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAEC 336
+E L + + ++++ E +EL + + +L EL EL+ + A
Sbjct: 1254 RTAVGKEAGELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALG 1313
Query: 337 MEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDI 396
E++ E LR + + S ++ + E++ RK L+E E
Sbjct: 1314 ERAEKESRRETLGLRQRLLKGEAS----------LEVMRQELQVAQRK---LQEQEGEFR 1360
Query: 397 THQKRVFETVRNINQVVKQR 416
T ++R+ ++ KQ+
Sbjct: 1361 TRERRLLGSLEEARGTEKQQ 1380
Score = 36.6 bits (83), Expect = 0.11
Identities = 57/247 (23%), Positives = 93/247 (37%), Gaps = 26/247 (10%)
Query: 160 EVSQLRHELSMKDELLQFYTSAAEESEPES-VCSTPLKRNESSSSVQNYFHLDSLQKKLK 218
+V +R +LL +SE E L+R + H D+ Q++++
Sbjct: 534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDA-QREVQ 592
Query: 219 DLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKK----- 273
L N +L E S L Q+ +ELR ++ + EEL ++
Sbjct: 593 RLRSANELLSREKSNLAHSL--------QVAQQQAEELRQEREKLQAAQEELRRQRDRLE 644
Query: 274 ------TEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELR 327
+D AR + E+ Q+ L+ K A E E+ + L A + L AE
Sbjct: 645 EEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKA 704
Query: 328 ELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPM-DSLAAEIEGTMRKEL 386
E+ AE + + EL+ K S + L + +SLA + R
Sbjct: 705 EV----AEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVA 760
Query: 387 QLEEAES 393
QLEE +S
Sbjct: 761 QLEEEKS 767
Score = 36.2 bits (82), Expect = 0.15
Identities = 58/253 (22%), Positives = 111/253 (43%), Gaps = 30/253 (11%)
Query: 100 ERVGQMTKTYNDIDAVTRLLEE-------KERDLELAARIGQSLLKKNKT-LTERN---E 148
E++ +M ++ R L+E + LEL R + L++++ L++R +
Sbjct: 1621 EKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQ 1680
Query: 149 LLEEQVEHIREEVSQLRHE---LSMKDELLQFYTSAAEESEP---ESVCSTPLKRNESSS 202
L+++V+ ++ +V+ + L + E L + EESE + V +SS+
Sbjct: 1681 ALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSA 1740
Query: 203 SVQNYFHLD-SLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELR---- 257
S+ + + LQK L E + VL+ + + ++ K+ + + V+ LR
Sbjct: 1741 SLNSTRDKNLHLQKALTACEHDRQVLQERLDAAR-QALSEARKQSSSLGEQVQTLRGEVA 1799
Query: 258 DANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKD 317
D +Q +L + E ++QE L+ + LQ E L + LG+ +
Sbjct: 1800 DLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQD-------ERRLLQERLGSLQR 1852
Query: 318 AQRQLTAELRELE 330
A QL AE RE+E
Sbjct: 1853 ALAQLEAEKREVE 1865
Score = 35.4 bits (80), Expect = 0.26
Identities = 62/304 (20%), Positives = 115/304 (37%), Gaps = 44/304 (14%)
Query: 70 LHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELA 129
L+ L +A D T + + K E + + + A L EE R E
Sbjct: 1535 LNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRLSGVQAELALQEESVRRSERE 1594
Query: 130 ARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPES 189
R + L + TL + E ++ +E++S+++ + + + + SE +
Sbjct: 1595 RR---ATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRT 1651
Query: 190 VCSTPLKRNESSSSVQN---------------YFHLDSLQKKLKDLEEENVVLRSEASQL 234
V L+R +Q +DSLQ+++ D E + L+ +L
Sbjct: 1652 V-KLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERL 1710
Query: 235 KTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDL 294
EE E L RD ++ ++E LA+ + +++ HL
Sbjct: 1711 NGALAKVEESEGAL--------RD---KVRGLTEALAQSSASLNSTRDKNLHL------- 1752
Query: 295 QKKAKACAVENEELVQHLGAAKDA-------QRQLTAELRELEDKYAECMEMLHEAQEEL 347
QK AC + + L + L AA+ A L +++ L + A+ EA+ +L
Sbjct: 1753 QKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQL 1812
Query: 348 KNLR 351
+ LR
Sbjct: 1813 QQLR 1816
Score = 33.9 bits (76), Expect = 0.74
Identities = 32/137 (23%), Positives = 60/137 (43%), Gaps = 11/137 (8%)
Query: 290 QIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKN 349
Q+ D++ + +A L + L ++ +R L +L+ L DK M+ +AQ E++
Sbjct: 534 QVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQR 593
Query: 350 LR--NKTMPNTTSRRYHSLGLFPM---------DSLAAEIEGTMRKELQLEEAESPDITH 398
LR N+ + S HSL + + L A E R+ +LEE + +
Sbjct: 594 LRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQD 653
Query: 399 QKRVFETVRNINQVVKQ 415
RV + ++ ++Q
Sbjct: 654 GARVRRELERSHRQLEQ 670
Score = 32.3 bits (72), Expect = 2.2
Identities = 49/231 (21%), Positives = 95/231 (41%), Gaps = 16/231 (6%)
Query: 114 AVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKD- 172
A+ RL EE++R LA ++ L ++ N+ L E + + + ++ R EL ++
Sbjct: 218 ALIRLEEEQQRSASLA-QVNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHREA 276
Query: 173 ------ELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQ------KKLKDL 220
E Y S E S + + S V+ + D LQ + + +
Sbjct: 277 AWRREEESFNAYFSN-EHSRLLLLWRQVVGFRRLVSEVKMFTERDLLQLGGELARTSRAV 335
Query: 221 EEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQ 280
+E + L + ++ EK+ L ++LRD ++ ++++ + D A
Sbjct: 336 QEAGLGLSTGLRLAESRAEAALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADL 395
Query: 281 QEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELED 331
+T L + L+K+ N++L + L A + + Q A L E ED
Sbjct: 396 SARVTELGLAVKRLEKQNLEKDQVNKDLTEKLEALESLRLQEQAAL-ETED 445
>gi|119120918 coiled-coil domain containing 64 [Homo sapiens]
Length = 573
Score = 63.5 bits (153), Expect = 9e-10
Identities = 74/308 (24%), Positives = 131/308 (42%), Gaps = 43/308 (13%)
Query: 99 AERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIR 158
AE G D + ++ ++ +KE+DL LAAR+G++LL++N+ ++ + E + +++
Sbjct: 84 AEGAGPQPPPSQDPELLS-VIRQKEKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKL 142
Query: 159 EEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLK 218
E + Q +HEL + E E E E S L+S K+L+
Sbjct: 143 EHLEQEKHELRRRFE--------NREGEWEGRVS----------------ELESDVKQLQ 178
Query: 219 D-LEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDA 277
D LE + + LR EA + K+ + ++ Q + D +L A+ +S ++ ED
Sbjct: 179 DELERQQIHLR-EADREKSRAVQELSEQNQRLLD---QLSRASEVERQLSMQVHALREDF 234
Query: 278 ARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECM 337
+ + ++ LQ + K + EL L A + L + EL+D+
Sbjct: 235 REKNSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDLLQGTVEELQDRVLILE 294
Query: 338 E-------MLHEAQEELKNLR------NKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRK 384
LH++Q EL+ +R + T R SL +EIE +M
Sbjct: 295 RQGHDKDLQLHQSQLELQEVRLSCRQLQVKVEELTEERSLQSSAATSTSLLSEIEQSMEA 354
Query: 385 ELQLEEAE 392
E +E E
Sbjct: 355 EELEQERE 362
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 63.2 bits (152), Expect = 1e-09
Identities = 84/355 (23%), Positives = 156/355 (43%), Gaps = 54/355 (15%)
Query: 99 AERVGQMTKTYNDIDAVTRLLEEKERDL-----ELAARIGQSLLKKNKTLTERN-ELLEE 152
A+ V ++ + +++ V + LE+++ +L ++A+ I L K+K+ ER +E+
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNI--EALSKSKSNIERTCRTVED 1258
Query: 153 QVEHIR---EEVSQLRHELSMKDELLQFYTSAAEE--SEPESVCSTPLKRNESSSSVQNY 207
Q I+ E+ +QL H+L+M+ LQ E ES+ S K ++ +
Sbjct: 1259 QFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQ---- 1314
Query: 208 FHLDSLQKKLKDLEEENVVLRSEASQLKTETITYE------EKEQQLVNDCVKELRDANV 261
L++ + +EEE + A L++ + E+EQ+ + + L AN
Sbjct: 1315 ----QLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANS 1370
Query: 262 QIASIS--------------EELAKKTEDAARQQEEITHLL-SQIVDLQKKAKACAVENE 306
++A EE KK ++ EE T S+ L+K + E E
Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVE 1430
Query: 307 ELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSL 366
+L++ L + A L + R + AE + L E+Q EL+ + ++ R S
Sbjct: 1431 DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKES-------RSLST 1483
Query: 367 GLFPMDSLAAEIEG---TMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSL 418
LF M + E+ T+R+E + + E D+T Q + ET +N+ + K + L
Sbjct: 1484 ELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQ--IAETGKNLQEAEKTKKL 1536
Score = 48.1 bits (113), Expect = 4e-05
Identities = 54/272 (19%), Positives = 120/272 (44%), Gaps = 15/272 (5%)
Query: 76 SPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLE-LAARIGQ 134
S N+ E+ E +K +L +V ++T+ + + + L K+R+LE + + +
Sbjct: 897 SETENLMDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKR 956
Query: 135 SLLKKNKTLTE---RNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVC 191
+ TLT+ E +V+++ EE++ L +S L + +E+ +++
Sbjct: 957 DIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISK----LTKEKKSLQEAHQQTLD 1012
Query: 192 STPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVND 251
++ ++ + ++ L+ L+ E+ LR++ + K + E + ++ +
Sbjct: 1013 DLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKL----EGDLKMSQE 1068
Query: 252 CVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQH 311
+ +L + QI E+L KK + ++ Q +I + QKK K EEL +
Sbjct: 1069 SIMDLENDKQQI---EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEE 1125
Query: 312 LGAAKDAQRQLTAELRELEDKYAECMEMLHEA 343
+ A + ++ + +L + E E L EA
Sbjct: 1126 IEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157
Score = 45.1 bits (105), Expect = 3e-04
Identities = 60/270 (22%), Positives = 113/270 (41%), Gaps = 39/270 (14%)
Query: 74 LISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLE-------EKERDL 126
LI +A ++ T+ +E +L+ Q K D++ R LE E DL
Sbjct: 1024 LIKINAKLEQQTDDLEGSLE----------QEKKLRADLERAKRKLEGDLKMSQESIMDL 1073
Query: 127 ELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESE 186
E + + LKK + EL + Q + E+V L+ + +K EL EE E
Sbjct: 1074 ENDKQQIEEKLKKKEF-----ELSQLQAKIDDEQVHSLQFQKKIK-ELQARIEELEEEIE 1127
Query: 187 PESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQ 246
E +++ S L ++L+++ E EAS + I +K +
Sbjct: 1128 AEHTLRAKIEKQRSD-----------LARELEEISER----LEEASGATSAQIEMNKKRE 1172
Query: 247 QLVNDCVKELRDANVQIASISEELAKKTEDA-ARQQEEITHLLSQIVDLQKKAKACAVEN 305
++L +A +Q + + L KK D+ A E+I +L L+K+ +E
Sbjct: 1173 AEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEI 1232
Query: 306 EELVQHLGAAKDAQRQLTAELRELEDKYAE 335
+++ ++ A ++ + R +ED+++E
Sbjct: 1233 DDMASNIEALSKSKSNIERTCRTVEDQFSE 1262
Score = 44.3 bits (103), Expect = 6e-04
Identities = 61/284 (21%), Positives = 125/284 (44%), Gaps = 27/284 (9%)
Query: 146 RNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEP--ESVCSTPLKRNESSSS 203
R + LEE++ + +E + L+ ++ + E L A E E +S K E +
Sbjct: 873 RRKELEEKMVSLLQEKNDLQLQVQSETENLM---DAEERCEGLIKSKILLEAKVKELTER 929
Query: 204 VQNYFHLDS-LQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQ 262
++ ++S L K ++LE++ L+ + L+ T+T EKE+ + VK L + +
Sbjct: 930 LEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLEL-TLTKVEKEKHATENKVKNLSE---E 985
Query: 263 IASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQH---LGAAKDAQ 319
+ ++ E ++K T++ QE L + + K N +L Q L + + +
Sbjct: 986 MTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQE 1045
Query: 320 RQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIE 379
++L A+L + K ++M E+ +L+N + + + F + L A+I+
Sbjct: 1046 KKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKE------FELSQLQAKID 1099
Query: 380 GTMRKELQLE------EAESPDITHQKRVFETVRNINQVVKQRS 417
LQ + +A ++ + T+R ++ KQRS
Sbjct: 1100 DEQVHSLQFQKKIKELQARIEELEEEIEAEHTLR--AKIEKQRS 1141
Score = 43.5 bits (101), Expect = 0.001
Identities = 73/343 (21%), Positives = 140/343 (40%), Gaps = 73/343 (21%)
Query: 100 ERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIRE 159
E++ + K + + +L+E+++ DL++A E +E +EH
Sbjct: 1518 EQIAETGKNLQEAEKTKKLVEQEKSDLQVAL-----------------EEVEGSLEHEES 1560
Query: 160 EVSQLRHELS-MKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDS------ 212
++ +++ ELS +K EL + EE E LKRN ++ LD+
Sbjct: 1561 KILRVQLELSQVKSELDRKVIEKDEEIE-------QLKRNSQRAAEALQSVLDAEIRSRN 1613
Query: 213 ----LQKKLK-DLEEENVVL-----RSEASQLKTETITYEEKEQQL-VNDCVKELRDANV 261
L+KK++ DL E + L + +Q T+ + K+ QL ++D ++ D
Sbjct: 1614 DALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKE 1673
Query: 262 QIASISEE---LAKKTED--AARQQEEITHLLS--QIVDLQKKAKACAVENEELVQHLGA 314
Q+A + L ++ E+ A +Q E T LS +++D + + +N L+
Sbjct: 1674 QLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQNTSLIN---- 1729
Query: 315 AKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSL 374
++LE A+C + + +E +N K T + L
Sbjct: 1730 ----------TKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDT 1779
Query: 375 AAEIEGTMRKELQ---------LEEAESPDITHQKRVFETVRN 408
+A +E M+K L+ L+EAE + K+ + + N
Sbjct: 1780 SAHLE-RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEN 1821
Score = 42.0 bits (97), Expect = 0.003
Identities = 75/439 (17%), Positives = 158/439 (35%), Gaps = 55/439 (12%)
Query: 119 LEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFY 178
L+E + +LE A + +SL + + E + +Q+E +R E L+ E+S E +
Sbjct: 1464 LDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAET 1523
Query: 179 TSAAEESEPESVCSTPLK--------------RNESSSSVQNYFHLDS----LQKKLKDL 220
+E+E K +E S ++ L L +K+ +
Sbjct: 1524 GKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEK 1583
Query: 221 EEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQ 280
+EE L+ + + + + E + ND ++ + + + +L A
Sbjct: 1584 DEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAET 1643
Query: 281 QEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEML 340
Q+ + + Q+ D Q NE+L + L + L EL E++ +
Sbjct: 1644 QKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTR 1703
Query: 341 HEAQEELKNL---------RNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEA 391
+++EL + +N ++ NT + + AE+E ++++ EE
Sbjct: 1704 RLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIA-----QCQAEVENSIQESRNAEEK 1758
Query: 392 ESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYG 451
IT + E +K+ T + + N + L + + G
Sbjct: 1759 AKKAITDAAMMAEE-------LKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKG 1811
Query: 452 SDIGNVVLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRRENYLS 511
L+N+ + E + +K G G+H E ++ ++ + E
Sbjct: 1812 GKKQIQKLENRVRELENELDV--------EQKRGAEALKGAHKYERKVKEMTYQAEE--- 1860
Query: 512 ERRFFEEEQERKLQELAEK 530
+ + +LQ+L +K
Sbjct: 1861 -----DHKNILRLQDLVDK 1874
Score = 38.5 bits (88), Expect = 0.030
Identities = 56/250 (22%), Positives = 110/250 (44%), Gaps = 44/250 (17%)
Query: 113 DAVTRLLEEKERDLELAARIGQSLL----KKNKTLTERNELLEEQVEHIREEVSQLRHEL 168
+ + LL+EK DL+L + L ++ + L + LLE +V+ + E +L E
Sbjct: 879 EKMVSLLQEKN-DLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELTE---RLEEEE 934
Query: 169 SMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKL----------- 217
M EL+ A++ E CS+ LKR+ +D L+ L
Sbjct: 935 EMNSELV------AKKRNLEDKCSS-LKRD-----------IDDLELTLTKVEKEKHATE 976
Query: 218 ---KDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKT 274
K+L EE L S+L E + +E QQ ++D E N + I+ +L ++T
Sbjct: 977 NKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVN-GLIKINAKLEQQT 1035
Query: 275 EDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYA 334
+D E+ L + + ++K + ++E + L ++ ++Q+ +L++ E + +
Sbjct: 1036 DDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDL---ENDKQQIEEKLKKKEFELS 1092
Query: 335 ECMEMLHEAQ 344
+ + + Q
Sbjct: 1093 QLQAKIDDEQ 1102
Score = 30.4 bits (67), Expect = 8.2
Identities = 23/103 (22%), Positives = 50/103 (48%), Gaps = 7/103 (6%)
Query: 258 DANVQIASISEELAKKTEDAARQQ-------EEITHLLSQIVDLQKKAKACAVENEELVQ 310
+A ++A++ E+ + E+ AR + E++ LL + DLQ + ++ + +
Sbjct: 848 EAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEE 907
Query: 311 HLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNK 353
++ L A+++EL ++ E EM E + +NL +K
Sbjct: 908 RCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDK 950
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 63.2 bits (152), Expect = 1e-09
Identities = 67/344 (19%), Positives = 152/344 (44%), Gaps = 48/344 (13%)
Query: 100 ERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIRE 159
ER+ +M + ++ L+ ER+ L Q L++ KTLT+ + L++ E ++
Sbjct: 884 ERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQI 943
Query: 160 EVSQLRHEL----SMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQK 215
E QL+ ++ +M + + +A E + LK ++ S V H++
Sbjct: 944 ERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLK-SKISEEVSRNLHMEENTG 1002
Query: 216 KLKDLEEENVV---LRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAK 272
+ KD ++ +V + + T+T+T + K+ +++ E + + EL +
Sbjct: 1003 ETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEII-----EQQRKIFSLIQEKNELQQ 1057
Query: 273 KTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAE------- 325
E ++E++ L + +++ +EN+E ++ LG Q+++ A+
Sbjct: 1058 MLESVIAEKEQLKTDLKENIEM-------TIENQEELRLLGDELKKQQEIVAQEKNHAIK 1110
Query: 326 -----------LRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSL 374
L E+E+K E + L E Q++L N++ + + ++ + + ++L
Sbjct: 1111 KEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEM--SEMQKKINEI-----ENL 1163
Query: 375 AAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSL 418
E++ KEL LE E+ + +++ E + + K+R +
Sbjct: 1164 KNELK---NKELTLEHMETERLELAQKLNENYEEVKSITKERKV 1204
Score = 56.2 bits (134), Expect = 1e-07
Identities = 63/293 (21%), Positives = 129/293 (44%), Gaps = 46/293 (15%)
Query: 100 ERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKN------------------- 140
+ V + +T N+++ +T + +D ARI L+ N
Sbjct: 1296 KEVSETQETMNELELLTE--QSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDN 1353
Query: 141 -KTLTERNELLEEQV-EHIREEVSQLRHELSMKDELLQFY------TSAAEESEPESVCS 192
KT+ E E+ +Q+ EHIRE +++++ S +++ L T E E
Sbjct: 1354 LKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKD 1413
Query: 193 TPLKRNE------SSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKT---ETITYE- 242
+ L R E S +++ + S+ K+ DL+ VL+SE+ QLK E +
Sbjct: 1414 SALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHL 1473
Query: 243 --EKEQQLVNDCVKE----LRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQK 296
E+E ++ + C+KE + + V ++ E++ + +++ + + +I + ++
Sbjct: 1474 ETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEE 1533
Query: 297 KAKACAV-ENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELK 348
+ + E +E V L K+ ++ + L+ +E K E L E+QEE++
Sbjct: 1534 QFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQ 1586
Score = 55.8 bits (133), Expect = 2e-07
Identities = 77/346 (22%), Positives = 141/346 (40%), Gaps = 68/346 (19%)
Query: 104 QMTKTYNDIDAVTRLLEEKER-----DLELAARIGQSLLKKNKTLTERNELLEE-----Q 153
++ +N+I +T L++ K +LEL +I + NK + E L EE +
Sbjct: 689 ELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSE 748
Query: 154 VEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESV--------------------CST 193
++ + EV +LR E+ K E L TS ++ E V +T
Sbjct: 749 LKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATT 808
Query: 194 PLKRNESSSSVQNY--FHLDSLQKKLKDLEE------ENVVLRSEASQ-------LKTET 238
+ QN+ H+D QK LEE E V L EA + LKTE
Sbjct: 809 QSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTE- 867
Query: 239 ITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKA 298
++Y+ +E Q + +E+++ ++ + E+L + + E T + ++ ++
Sbjct: 868 LSYKTQELQ---EKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEV 924
Query: 299 KACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNT 358
K E ++L K Q L E +L+ + + M + QE+L+N +
Sbjct: 925 KTLTQEKDDL-------KQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQ 977
Query: 359 TSRRYHSLGLFPMDSLAAEIEGTMRKELQLEE--AESPDITHQKRV 402
+ +++L ++I + + L +EE E+ D QK V
Sbjct: 978 ET----------INTLKSKISEEVSRNLHMEENTGETKDEFQQKMV 1013
Score = 52.8 bits (125), Expect = 2e-06
Identities = 67/311 (21%), Positives = 141/311 (45%), Gaps = 45/311 (14%)
Query: 122 KERDLELAARIGQSLLKKNKTL--TERNELLEE--QVEHIREEVSQLRHELSMKDELLQF 177
KE E+ A++ +S K+ + L T NE E+ ++EH++E+ + L
Sbjct: 1610 KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNL--------- 1660
Query: 178 YTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKT- 236
E E E++ T + +N + S+ K+ DL L+ E QLK
Sbjct: 1661 -----ENIETENIRLTQILH-------ENLEEMRSVTKERDDLRSVEETLKVERDQLKEN 1708
Query: 237 --ETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITH----LLSQ 290
ETIT + ++Q+ + L++ I + +++KT + + Q+++ H L +Q
Sbjct: 1709 LRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQ 1768
Query: 291 IVDLQKKAKACAV---ENEELVQHL-GAAKDAQRQLTAELRELEDKYAECMEMLHEAQ-E 345
+ +Q++ + + E +E + L G + +L+ ++LE+ A+ E + E +
Sbjct: 1769 DLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKAN 1828
Query: 346 ELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFET 405
E + + K N T ++ + M+ L +I+ + L L + E ++ +++ E
Sbjct: 1829 EHQLITLKKDVNETQKK-----VSEMEQLKKQIKD---QSLTLSKLEIENLNLAQKLHEN 1880
Query: 406 VRNINQVVKQR 416
+ + V+K+R
Sbjct: 1881 LEEMKSVMKER 1891
Score = 50.1 bits (118), Expect = 1e-05
Identities = 62/348 (17%), Positives = 144/348 (41%), Gaps = 63/348 (18%)
Query: 134 QSLLKKNKTLTERNELLEEQVEHIREEVSQL-RHELSMKDELLQFYTSAAEESEPESVCS 192
+S+ K+ L E+L+ + + ++E + ++ L ++EL + E+ E +
Sbjct: 1438 KSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELR 1497
Query: 193 TPLKRNESS-SSVQNYFHL--DSLQKKLKDLEEE----NVVLRSEASQLKTETITYEEKE 245
L E+ S++Q D LQ K++++ E+ N+ SE + E ++E
Sbjct: 1498 VNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEH- 1556
Query: 246 QQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVEN 305
++ +D+ +Q SI ++ + T QEEI ++ + ++++ +A +E
Sbjct: 1557 --------RKAKDSALQ--SIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIER 1606
Query: 306 EELVQHLGAAKDAQRQLTAELRELEDKYAECMEM--LHEAQEE----------------- 346
++L K+ +++ A+++E ++K + ++M ++E QE+
Sbjct: 1607 DQL-------KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLN 1659
Query: 347 ------------------LKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQL 388
L+ +R+ T R D L + T+ ++L+
Sbjct: 1660 LENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEK 1719
Query: 389 EEAESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNS 436
+E H K ET+ + +V +++ S M + + A+ +
Sbjct: 1720 QEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKA 1767
Score = 45.1 bits (105), Expect = 3e-04
Identities = 62/340 (18%), Positives = 141/340 (41%), Gaps = 30/340 (8%)
Query: 46 LLEEQLPHYKLRADTIYGYDHDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQM 105
L E+Q KLR D + L + +A + ++++ + + V +
Sbjct: 1783 LKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET 1842
Query: 106 TKTYNDIDAVTRLLEEKE--------RDLELAARIGQSLLKKNKTLTERNEL--LEEQVE 155
K ++++ + + ++++ +L LA ++ ++L + + ER+ L +EE ++
Sbjct: 1843 QKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLK 1902
Query: 156 HIREEVSQLRHELSMKD-ELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYF------ 208
R+++ + E +D E+ Q +A S+ L+ S ++Q
Sbjct: 1903 LERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLD 1962
Query: 209 -HLDSLQKKLKDLEEENVVLRS-----EASQLKTETITYEEKEQQLVNDCVKELRDANVQ 262
D LQKK+++L+++ + L S K + +K+ + N ++ +R N Q
Sbjct: 1963 KSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQ 2022
Query: 263 IASISEE-------LAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAA 315
+ E +AK+ ++ R +E + Q + ++ A +N ++
Sbjct: 2023 LTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLL 2082
Query: 316 KDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTM 355
D Q+ LT LRE + E ++ E + + L ++
Sbjct: 2083 SDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSL 2122
Score = 39.3 bits (90), Expect = 0.018
Identities = 68/295 (23%), Positives = 119/295 (40%), Gaps = 47/295 (15%)
Query: 107 KTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRH 166
K ND+D L + ++D E+ S LK L + E+ + +E+ +L
Sbjct: 529 KEKNDLDEFEALERKTKKDQEMQLIHEISNLKN---LVKHAEVYNQDLENELSSKVELLR 585
Query: 167 ELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSV-QNYFHLDSLQKKLKDLEEENV 225
E + + LQ Y + + + S L+ E + Q F +++ D + E+
Sbjct: 586 EKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVAL---DAKRESA 642
Query: 226 VLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEIT 285
LRSE +LK + +Q+ ND +Q+ E KK +
Sbjct: 643 FLRSENLELKEKMKELATTYKQMEND---------IQLYQSQLEAKKKMQ---------- 683
Query: 286 HLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQE 345
VDL+K+ ++ E +L + + L L ELE K + + L++ E
Sbjct: 684 ------VDLEKELQSAFNEITKLTSLIDG--KVPKDLLCNL-ELEGKITDLQKELNKEVE 734
Query: 346 ELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQK 400
E + LR + + L + SL +E+E +RKE+Q + E IT +K
Sbjct: 735 ENEALREEV-----------ILLSELKSLPSEVE-RLRKEIQDKSEELHIITSEK 777
Score = 37.7 bits (86), Expect = 0.051
Identities = 81/390 (20%), Positives = 150/390 (38%), Gaps = 89/390 (22%)
Query: 80 NIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSL--- 136
NID T EQ+ L E + Q +T N + + ++ EE R+L + G++
Sbjct: 959 NID-TQEQLRNAL-------ESLKQHQETINTLKS--KISEEVSRNLHMEENTGETKDEF 1008
Query: 137 --------------LKKNKTLT---ERNELLEEQVEHIREEVSQLRHELSMKDELLQFYT 179
K +TLT + NE++E+Q ++ L E K+EL Q
Sbjct: 1009 QQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQ-----RKIFSLIQE---KNELQQMLE 1060
Query: 180 SAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKD-----LEEENVVLRSEAS-- 232
S E E T LK N +++N L L +LK +E+N ++ E
Sbjct: 1061 SVIAEKEQ---LKTDLKEN-IEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELS 1116
Query: 233 -----------QLKTETITYEEKEQQLVN----------------DCVKELRDANVQIAS 265
+LK ++ +EK+QQL+N + EL++ + +
Sbjct: 1117 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEH 1176
Query: 266 ISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAE 325
+ E + + EE+ + + L++ K+ E + L ++ + Q E
Sbjct: 1177 METERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEE 1236
Query: 326 -------LRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRR-----YHSLGLFPMDS 373
L+E ++ E + E ++ N ++ +T + + L P
Sbjct: 1237 LKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVK 1296
Query: 374 LAAEIEGTMRK-ELQLEEAESPDITHQKRV 402
+E + TM + EL E++ + D T R+
Sbjct: 1297 EVSETQETMNELELLTEQSTTKDSTTLARI 1326
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 61.6 bits (148), Expect = 3e-09
Identities = 115/538 (21%), Positives = 215/538 (39%), Gaps = 68/538 (12%)
Query: 19 LCHGK-LIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADTIYGYDHDDWLHTPLISP 77
LCH + ++ CD NS VEI +++E+ K + H L +
Sbjct: 819 LCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEK----VKCSLEITLKEKHQKELLSLKNEY 874
Query: 78 DANIDLTTEQIEET------LKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAAR 131
+ +D ++ EE LK L+C E V Q N + + EKE + L
Sbjct: 875 EGKLDGLIKETEENENKIKKLKGELVCLEEVLQ-----NKDNEFALVKHEKEAVICLQNE 929
Query: 132 IGQSLLKKNKTLTERN---ELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPE 188
Q LL+ + +N + L++ E + E++ +L E K +LL+ + E+S
Sbjct: 930 KDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSH-- 987
Query: 189 SVCSTPLKRNESSSSVQNYFHLDSLQK-------KLKDLEEENVVLRSEASQLKTETITY 241
LK E + V+ H+ +K L++L++EN + ++ + E I
Sbjct: 988 ------LKELEDTLQVR---HIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQE 1038
Query: 242 EEKEQQLVNDCVKELRDANVQI-------ASISEELAKKTEDAARQQEEITHLLSQIVDL 294
+EK+ Q + V +L D ++ + ++E+ E++ QQ+E L L
Sbjct: 1039 KEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSL-----L 1093
Query: 295 QKKAKACAVENEELVQHLGAAKDAQRQLTAELRELED-KYAECMEMLHEAQEELKNLRNK 353
+++ + E +L Q + + + AELR L + +C+ L EE N+
Sbjct: 1094 EQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKA 1153
Query: 354 TMPNTTSRRYHSLGLFP-MDSLAAEIEGTMRKELQ-LEEAESPDITHQKRVFETVRNINQ 411
+ TS + + + E++ + EL LE + IT Q+ +E + I
Sbjct: 1154 ELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAI--IQN 1211
Query: 412 VVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETE 471
+ K R S +N + T F + V++ + + E
Sbjct: 1212 LEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEF---KLEREVVEKELLEKVKHLE 1268
Query: 472 AADLGNDERSKKPGTPGTPG-SHDLETALR-RLSLRRENYLSERRFFEEEQERKLQEL 527
++ +K P T G S L L+ +L + +L + EE+++RK +E+
Sbjct: 1269 ------NQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQ---LEEQEKRKNEEM 1317
Score = 51.6 bits (122), Expect = 3e-06
Identities = 96/449 (21%), Positives = 191/449 (42%), Gaps = 59/449 (13%)
Query: 86 EQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTE 145
E I+E K +V ++ T ++ V L+E E D E+ + +S ++ +TL
Sbjct: 1034 EIIQEKEKQLQELKLKVSDLSDTRCKLE-VELALKEAETD-EIKILLEESRAQQKETL-- 1089
Query: 146 RNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAE-----ESEPESVCSTPLKRNES 200
LLE++ E++R E+S+L ++ +E + AE E + S + R+E
Sbjct: 1090 -KSLLEQETENLRTEISKLNQKIQDNNE--NYQVGLAELRTLMTIEKDQCISELISRHEE 1146
Query: 201 SSSVQN---------YFHLDSLQKKLKD-LEEENVVLRSEASQL---KTETITYEEKE-- 245
S++ + ++K LK+ + E L SE S L K E IT +E++
Sbjct: 1147 ESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYE 1206
Query: 246 ---QQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACA 302
Q L D K + + ++L + ++A + + L ++V+ + K
Sbjct: 1207 AIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKH 1266
Query: 303 VENE-ELVQHLGAAKDAQRQLTAELRE-LEDKYAECMEMLHEAQ----EELKNLR----- 351
+EN+ + + + L AEL+E L+++ A+ +E L E + EE++N+R
Sbjct: 1267 LENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIA 1326
Query: 352 -NKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNIN 410
+T NT R ++ L+ +++ TM+++ + ++ + R+ E + +
Sbjct: 1327 EQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLE 1386
Query: 411 QVV---KQRSLTPSPM-------------NIPGSNQSSAMNSLLSSCVSTPRSSFYGSDI 454
+ V + S PSP +PG + SA+ + V + + S
Sbjct: 1387 EEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQ 1446
Query: 455 GNV-VLDNKTNSIILETEAADLGNDERSK 482
N+ +L + I+L L +E +
Sbjct: 1447 ENIHMLSEEKQRIMLLERTLQLKEEENKR 1475
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 61.6 bits (148), Expect = 3e-09
Identities = 115/538 (21%), Positives = 215/538 (39%), Gaps = 68/538 (12%)
Query: 19 LCHGK-LIRTNACDVCNSTDLPEVEIISLLEEQLPHYKLRADTIYGYDHDDWLHTPLISP 77
LCH + ++ CD NS VEI +++E+ K + H L +
Sbjct: 819 LCHFRTFVQKEQCDFSNSLKCTAVEIRNIIEK----VKCSLEITLKEKHQKELLSLKNEY 874
Query: 78 DANIDLTTEQIEET------LKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAAR 131
+ +D ++ EE LK L+C E V Q N + + EKE + L
Sbjct: 875 EGKLDGLIKETEENENKIKKLKGELVCLEEVLQ-----NKDNEFALVKHEKEAVICLQNE 929
Query: 132 IGQSLLKKNKTLTERN---ELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPE 188
Q LL+ + +N + L++ E + E++ +L E K +LL+ + E+S
Sbjct: 930 KDQKLLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSH-- 987
Query: 189 SVCSTPLKRNESSSSVQNYFHLDSLQK-------KLKDLEEENVVLRSEASQLKTETITY 241
LK E + V+ H+ +K L++L++EN + ++ + E I
Sbjct: 988 ------LKELEDTLQVR---HIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQE 1038
Query: 242 EEKEQQLVNDCVKELRDANVQI-------ASISEELAKKTEDAARQQEEITHLLSQIVDL 294
+EK+ Q + V +L D ++ + ++E+ E++ QQ+E L L
Sbjct: 1039 KEKQLQELKLKVSDLSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSL-----L 1093
Query: 295 QKKAKACAVENEELVQHLGAAKDAQRQLTAELRELED-KYAECMEMLHEAQEELKNLRNK 353
+++ + E +L Q + + + AELR L + +C+ L EE N+
Sbjct: 1094 EQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKA 1153
Query: 354 TMPNTTSRRYHSLGLFP-MDSLAAEIEGTMRKELQ-LEEAESPDITHQKRVFETVRNINQ 411
+ TS + + + E++ + EL LE + IT Q+ +E + I
Sbjct: 1154 ELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAI--IQN 1211
Query: 412 VVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETE 471
+ K R S +N + T F + V++ + + E
Sbjct: 1212 LEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEF---KLEREVVEKELLEKVKHLE 1268
Query: 472 AADLGNDERSKKPGTPGTPG-SHDLETALR-RLSLRRENYLSERRFFEEEQERKLQEL 527
++ +K P T G S L L+ +L + +L + EE+++RK +E+
Sbjct: 1269 ------NQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQ---LEEQEKRKNEEM 1317
Score = 51.6 bits (122), Expect = 3e-06
Identities = 96/449 (21%), Positives = 191/449 (42%), Gaps = 59/449 (13%)
Query: 86 EQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTE 145
E I+E K +V ++ T ++ V L+E E D E+ + +S ++ +TL
Sbjct: 1034 EIIQEKEKQLQELKLKVSDLSDTRCKLE-VELALKEAETD-EIKILLEESRAQQKETL-- 1089
Query: 146 RNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAE-----ESEPESVCSTPLKRNES 200
LLE++ E++R E+S+L ++ +E + AE E + S + R+E
Sbjct: 1090 -KSLLEQETENLRTEISKLNQKIQDNNE--NYQVGLAELRTLMTIEKDQCISELISRHEE 1146
Query: 201 SSSVQN---------YFHLDSLQKKLKD-LEEENVVLRSEASQL---KTETITYEEKE-- 245
S++ + ++K LK+ + E L SE S L K E IT +E++
Sbjct: 1147 ESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYE 1206
Query: 246 ---QQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACA 302
Q L D K + + ++L + ++A + + L ++V+ + K
Sbjct: 1207 AIIQNLEKDRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKH 1266
Query: 303 VENE-ELVQHLGAAKDAQRQLTAELRE-LEDKYAECMEMLHEAQ----EELKNLR----- 351
+EN+ + + + L AEL+E L+++ A+ +E L E + EE++N+R
Sbjct: 1267 LENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIA 1326
Query: 352 -NKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNIN 410
+T NT R ++ L+ +++ TM+++ + ++ + R+ E + +
Sbjct: 1327 EQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLE 1386
Query: 411 QVV---KQRSLTPSPM-------------NIPGSNQSSAMNSLLSSCVSTPRSSFYGSDI 454
+ V + S PSP +PG + SA+ + V + + S
Sbjct: 1387 EEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADEGRVDSAMETSMMSVQ 1446
Query: 455 GNV-VLDNKTNSIILETEAADLGNDERSK 482
N+ +L + I+L L +E +
Sbjct: 1447 ENIHMLSEEKQRIMLLERTLQLKEEENKR 1475
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 61.2 bits (147), Expect = 4e-09
Identities = 63/256 (24%), Positives = 122/256 (47%), Gaps = 25/256 (9%)
Query: 151 EEQVEHIREEVSQLRH---ELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNY 207
+E + + +EVS+L E KD ++ + E + +T ++NE S +
Sbjct: 227 DEIILLLGKEVSRLSDYEIESKYKDVIIANLQNEVAELSQKVSETTTSRQNEKEISQKCQ 286
Query: 208 F---HLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANV--- 261
+D+ QK+++ L+ + L+ S++ +T++ E + + + L+ N
Sbjct: 287 VLDEDIDAKQKEIQSLKSQISALQKGYSKVLCQTLSERNSEITSLKNEGENLKRDNAITS 346
Query: 262 -QIASISEELAKKTEDAARQQEEITHLLSQIVD----LQKKAKACAVENEELVQHLGAAK 316
++S+ +++ K E + +EE++HL SQ D L+ C+V EEL Q +
Sbjct: 347 GMVSSLQKDILAKDEQVQQLKEEVSHLKSQNKDKDHQLEALGSRCSVLKEELKQ-----E 401
Query: 317 DAQRQLTAELRELEDKYAE-CMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLA 375
DA R ELRE ++K + C + + ++E+K LR + + T + S L +
Sbjct: 402 DAHR----ELREAQEKELKLCKTQIQDMEKEMKKLRAELRKSCTEQSVISRTLREKSKVE 457
Query: 376 AEI-EGTMRKELQLEE 390
++ E + RK LQL+E
Sbjct: 458 EKLQEDSRRKLLQLQE 473
Score = 41.6 bits (96), Expect = 0.004
Identities = 52/219 (23%), Positives = 95/219 (43%), Gaps = 31/219 (14%)
Query: 78 DANIDLTT-EQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSL 136
DA DL T +IE LC R G + +D L ++ L+++ +G +
Sbjct: 1198 DAKPDLPTLSRIEILAPQNGLCNARFGSAMEKSGKMDVAEALELSEKLYLDMSKTLGSLM 1257
Query: 137 LKKN-------KTLTER-----NELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEE 184
KN K L+ + N+L + ++ + ++++QL+++L K+ELL+ Y E+
Sbjct: 1258 NIKNMSGHVSMKYLSRQEREKVNQLRQRDLDLVFDKITQLKNQLGRKEELLRGYEKDVEQ 1317
Query: 185 SEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKD---LEEENVVLRSEASQLKTETITY 241
L+R S S++ Y S KL+D E E L EA + +
Sbjct: 1318 ----------LRR--SKVSIEMY---QSQVAKLEDDIYKEAEEKALLKEALERMEHQLCQ 1362
Query: 242 EEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQ 280
E++ + + R A++++ E L K+T + Q
Sbjct: 1363 EKRINRAIRQQKVGTRKASLKMDQEREMLRKETSSKSSQ 1401
Score = 35.8 bits (81), Expect = 0.20
Identities = 79/439 (17%), Positives = 169/439 (38%), Gaps = 55/439 (12%)
Query: 105 MTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQL 164
+++ ++I ++ E +RD + + + SL K E+ + L+E+V H++ +
Sbjct: 321 LSERNSEITSLKNEGENLKRDNAITSGMVSSLQKDILAKDEQVQQLKEEVSHLKSQNKDK 380
Query: 165 RHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEEN 224
H+L E L S +E + L+ + + ++K++K L E
Sbjct: 381 DHQL----EALGSRCSVLKEELKQEDAHRELREAQEKELKLCKTQIQDMEKEMKKLRAE- 435
Query: 225 VVLRSEASQLKTETITYEEK---EQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQ 281
LR ++ + T EK E++L D ++L +Q+ + + + R
Sbjct: 436 --LRKSCTEQSVISRTLREKSKVEEKLQEDSRRKL----LQLQEMGNRESVIKINLERAV 489
Query: 282 EEITHLLSQIVDL----QKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECM 337
++ H SQ++ K + V +++L++ + Q+T + + K
Sbjct: 490 GQLEHFRSQVIKATYGRAKPFRDKPVTDQQLIEKI-------TQVTEDNINFQQK----- 537
Query: 338 EMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEE--AESPD 395
+ + + +L N + + + SL + ++KE+ L + SP
Sbjct: 538 KWTLQKETQLSNSKQEETTENIEKLRTSLDSCQACMKISCCSHDLKKEVDLLQHLQVSPP 597
Query: 396 ITH-QKRVFETVRN-------INQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRS 447
++ QK V + +R+ + Q+++ + PS N Q S +++ ++ + S
Sbjct: 598 VSGLQKVVLDVLRHALSWLEEVEQLLRDLGILPSSPNKDQVQQFSGNSAVFTAGKAAGAS 657
Query: 448 SFYGSDIGNVVLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRRE 507
G E A + +S+ T G G LE + + R +
Sbjct: 658 GREGE---------------AERGEARARGEAQSQNQATDGREGGKALEEYITQERNRAK 702
Query: 508 NYLSERRFFEEEQERKLQE 526
L E R +E E L +
Sbjct: 703 ETLEEERKRMQELESLLAQ 721
Score = 33.5 bits (75), Expect = 0.97
Identities = 60/287 (20%), Positives = 114/287 (39%), Gaps = 26/287 (9%)
Query: 84 TTEQIEETLKYFLLCAERV---GQMTKTYNDIDAVTR------LLEEKERDLELAARIGQ 134
T ++E T ++ ER+ +M K D R ++E KE+ + A I
Sbjct: 879 TLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQIKQHAQTI-V 937
Query: 135 SLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTP 194
SL +K + +T+ ++ +E ++ +++ + E + S+A++ E +
Sbjct: 938 SLEEKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLVAPMTESSAKDMAYEHLIDDL 997
Query: 195 LKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVK 254
L + S Q + + K KDL E + + +L + E+ LV K
Sbjct: 998 LAAQKEILSQQ-----EVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSK 1052
Query: 255 ELRDANVQIASISEELAKK------TEDAARQQEEITHLLSQIVDLQ----KKAKACAVE 304
EL ++A +S + KK E+A R +E H L + + KK + C
Sbjct: 1053 ELSVLKEKMAQMSSLVEKKDRELKALEEALRASQE-KHRLQLNTEKEQKPRKKTQTCDTS 1111
Query: 305 NEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLR 351
+ H A +Q Q + + K + E++ ++ L LR
Sbjct: 1112 VQIEPVHTEAFSSSQEQQSFSDLGVRCKGSRHEEVIQRQKKALSELR 1158
>gi|157502225 Janus kinase and microtubule interacting protein 3
[Homo sapiens]
Length = 844
Score = 60.5 bits (145), Expect = 7e-09
Identities = 83/313 (26%), Positives = 142/313 (45%), Gaps = 48/313 (15%)
Query: 85 TEQIEETLKYFLLCAERVG------QMTKTYNDIDAVTRLLEEKERDLELA-ARIGQSL- 136
T + + + + L E+VG + KT + A + + + DLE A A GQ +
Sbjct: 506 TMEYQALQRAYALLQEQVGGTLDAEREVKTREQLQAEVQRAQARIEDLEKALAEQGQDMK 565
Query: 137 -LKKNKTLTERNELLEEQVEHIREEVSQLRHELS---MKDELLQFYTSAAEESEPESVC- 191
+++ + L RN+ L E+++ + E ++LRHE+ ++ELL+F EE E +S
Sbjct: 566 WIEEKQALYRRNQELVEKIKQMETEEARLRHEVQDARDQNELLEFRILELEERERKSPAI 625
Query: 192 ---STPLKRNESSSSVQNYFHLD--------SLQKKLKDLEEENVVLRSEAS----QLKT 236
TP + S +Q Y + L KKL D+ +N L +E Q +T
Sbjct: 626 SFHHTPFV--DGKSPLQVYCEAEGVTDIVVAELMKKL-DILGDNANLTNEEQVVVIQART 682
Query: 237 ETITYEEKEQQLVNDCVKELRDANVQIAS-----------ISEELAKKTEDAARQQEEIT 285
+T EK Q + + L+ V + S + EEL + + + + I
Sbjct: 683 -VLTLAEKWLQQIEETEAALQRKMVDLESEKELFSKQKGYLDEELDYRKQALDQANKHIL 741
Query: 286 HLLSQIVD-LQKKAKACAVE---NEELVQHLGAAKDAQRQLTAELRELEDK-YAECMEML 340
L + + D LQ++A A E EE + A + +RQ+ +ELRE + + E ME+L
Sbjct: 742 ELEAMLYDALQQEAGAKVAELLSEEEREKLKVAVEQWKRQVMSELRERDAQILRERMELL 801
Query: 341 HEAQEELKNLRNK 353
AQ+ +K L +
Sbjct: 802 QLAQQRIKELEER 814
Score = 32.3 bits (72), Expect = 2.2
Identities = 61/286 (21%), Positives = 116/286 (40%), Gaps = 46/286 (16%)
Query: 76 SPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQS 135
SP+ +D E+ + F L ++ +++ ++ LL E+ +L R +S
Sbjct: 282 SPEQQLD------EKDARRFQL---KIAELSAIIRKLEDRNALLSEERNELLKRVREAES 332
Query: 136 ----LLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSA-AEESEPESV 190
LL KNK L+ +NE L H L + L+F T E + +
Sbjct: 333 QYKPLLDKNKRLSRKNE--------------DLSHALRRMENKLKFVTQENIEMRQRAGI 378
Query: 191 CSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVN 250
P N+ S Q+ +D L KL+ +E++N++ +L T + L
Sbjct: 379 IRRPSSLNDLDQS-QDEREVDFL--KLQIVEQQNLI-----DELSKTLETAGYVKSVLER 430
Query: 251 DCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQI-VDLQKKAKACAVENEELV 309
D + R ++A + + + +T ++ + S + + + +++L
Sbjct: 431 DKLLRFRKQRKKMAKLPKPVVVETFFGYDEEASLESDGSSVSYQTDRTDQTPCTPDDDLE 490
Query: 310 QHLGAAKDAQ----RQLTAELRELEDKYAECMEMLH---EAQEELK 348
+ G AK+ RQLT E + L+ YA E + +A+ E+K
Sbjct: 491 E--GMAKEETELRFRQLTMEYQALQRAYALLQEQVGGTLDAEREVK 534
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 60.1 bits (144), Expect = 1e-08
Identities = 75/324 (23%), Positives = 135/324 (41%), Gaps = 57/324 (17%)
Query: 118 LLEEKERDLELAARIGQSLLKKNKTLTERNEL-----------LEEQVEHIREEVSQLRH 166
L EEK+RD+ + +SL + + E L L+++ +H+R+EV L
Sbjct: 257 LKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEG 316
Query: 167 ELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHL----DSLQKKLKDLEE 222
+L + E Q + ++E + + R + + V+ L + L+++ K L+E
Sbjct: 317 KLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQE 376
Query: 223 ENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQE 282
+ LR + +L+ + ++E++L K L D E L KK E +Q+E
Sbjct: 377 QGERLRKQEQRLRKQEERLRKEEERLQKQ-EKRLWDQ-------EERLWKKEERLQKQEE 428
Query: 283 EITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHE 342
+ + +D Q C+ E+ L K + QL +++EL++K L E
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFED------LNNEKKSALQLEQQVKELQEK-------LDE 475
Query: 343 AQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRV 402
E + RN+ + S +A EG + L EE E+P T
Sbjct: 476 EHLEAASQRNQQLETQLS------------LVALPGEGDGGQHLDSEEEEAPRPT----- 518
Query: 403 FETVRNINQVVKQRSLTPSPMNIP 426
NI + ++ R T S M++P
Sbjct: 519 ----PNIPEDLESREATSSFMDLP 538
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 60.1 bits (144), Expect = 1e-08
Identities = 75/324 (23%), Positives = 135/324 (41%), Gaps = 57/324 (17%)
Query: 118 LLEEKERDLELAARIGQSLLKKNKTLTERNEL-----------LEEQVEHIREEVSQLRH 166
L EEK+RD+ + +SL + + E L L+++ +H+R+EV L
Sbjct: 257 LKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEG 316
Query: 167 ELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHL----DSLQKKLKDLEE 222
+L + E Q + ++E + + R + + V+ L + L+++ K L+E
Sbjct: 317 KLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQE 376
Query: 223 ENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQE 282
+ LR + +L+ + ++E++L K L D E L KK E +Q+E
Sbjct: 377 QGERLRKQEQRLRKQEERLRKEEERLQKQ-EKRLWDQ-------EERLWKKEERLQKQEE 428
Query: 283 EITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHE 342
+ + +D Q C+ E+ L K + QL +++EL++K L E
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFED------LNNEKKSALQLEQQVKELQEK-------LDE 475
Query: 343 AQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRV 402
E + RN+ + S +A EG + L EE E+P T
Sbjct: 476 EHLEAASQRNQQLETQLS------------LVALPGEGDGGQHLDSEEEEAPRPT----- 518
Query: 403 FETVRNINQVVKQRSLTPSPMNIP 426
NI + ++ R T S M++P
Sbjct: 519 ----PNIPEDLESREATSSFMDLP 538
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 59.7 bits (143), Expect = 1e-08
Identities = 77/338 (22%), Positives = 145/338 (42%), Gaps = 49/338 (14%)
Query: 97 LCAERVGQMTKTYNDID----AVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEE 152
+ A++V ++ + ++D + + LEE E D+E + + L ++ L E + L E
Sbjct: 1692 ILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAE 1751
Query: 153 QVEHI---REEVSQLRHELSMKDELL-QFYTSAAEESE--PESVCSTPLKRNESSSSVQN 206
+ E + RE++S+ +L+ ++ELL Q A+ E PE KR +
Sbjct: 1752 EEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL------ 1805
Query: 207 YFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASI 266
++KK+K ++ + S K + I Y++K L +A
Sbjct: 1806 ------IEKKMKLAQKRERWINSMEELTKNKMILYQKKN----------LAQEKKNLAQE 1849
Query: 267 SEELAKKTEDAARQQEEITHLLSQIVDLQKKA----KACAVENEELVQHLGAA---KDAQ 319
E+LA++ E+ +E +TH Q+V ++ K K A E+L Q K+
Sbjct: 1850 KEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKL 1909
Query: 320 RQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGL--------FPM 371
+ +L ++ED A+ E L AQE++K K M R L + M
Sbjct: 1910 AETEKKLVQVEDSLAKKQEKL--AQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEM 1967
Query: 372 DSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNI 409
LA E + + L + E+P+ + Q+++ + + +
Sbjct: 1968 KRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQEL 2005
Score = 39.3 bits (90), Expect = 0.018
Identities = 54/264 (20%), Positives = 115/264 (43%), Gaps = 27/264 (10%)
Query: 118 LLEEKERDLELAARIGQSLL----KKNKTLTERNELLEEQV----EHIREEVSQLRHELS 169
L E+K+ E ++ +++L K+ + E LEE+V E ++V++ + +
Sbjct: 1510 LQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQ 1569
Query: 170 MKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRS 229
+ + + + A + + L + E + + L ++ + L + V +
Sbjct: 1570 EEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEER----QLAQEERKLAQAYVKITQ 1625
Query: 230 EASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQE------- 282
+ ++ + +KE+ L K ++A ++A ++LAKK E AR++E
Sbjct: 1626 DDREMAQAEGKFAQKEETLAQRGEKLSQEAE-KLAQKRKKLAKKWEKVAREEEKLAKKGG 1684
Query: 283 ---EITHLLSQ-IVDLQKKAKACAVENEELVQHLGAAKDAQRQLT---AELRELEDKYAE 335
E+ ++L+Q + +L ++ + + +EL Q L + +L+ EL + E K E
Sbjct: 1685 KLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVE 1744
Query: 336 CMEMLHEAQEELKNLRNKTMPNTT 359
+ L E +E L R K T
Sbjct: 1745 EKKKLAEEEEALAWQREKLSEEET 1768
Score = 36.6 bits (83), Expect = 0.11
Identities = 41/190 (21%), Positives = 78/190 (41%), Gaps = 16/190 (8%)
Query: 152 EQVEHIREEVSQLRHELSMKDELL---QFYTSAAEESEPESVCSTPLKRNESSSSVQNYF 208
E EH EE+ L EL ++ L + EE E E V +R E +
Sbjct: 2221 ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV 2280
Query: 209 HLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASIS- 267
+ +KK K E+ + E Q K E +EEKE+ + + + L D + S S
Sbjct: 2281 EKEEEEKKKKKKEK-----KKEEVQEKEE--VFEEKEEIMSEEETESLSDEEEEEESCSL 2333
Query: 268 EELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAV-----ENEELVQHLGAAKDAQRQL 322
EE + ++ +++++ + L+ + + ++ + LG K ++L
Sbjct: 2334 EEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRAIRLGVLKSPLKKL 2393
Query: 323 TAELRELEDK 332
+ E+++K
Sbjct: 2394 MSTALEMKEK 2403
Score = 35.8 bits (81), Expect = 0.20
Identities = 51/265 (19%), Positives = 103/265 (38%), Gaps = 8/265 (3%)
Query: 158 REEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKL 217
RE +S+ +L+ + LQ T + E + T +KR + L K
Sbjct: 2063 RESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKE 2122
Query: 218 KDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDA 277
D E+ L + +L + K ++++N K + + SE + E+
Sbjct: 2123 WDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEG 2182
Query: 278 ARQQEEITHLLSQIVDLQKKAKACAVENEEL---VQHLGAAKDAQRQLTAELRELEDKYA 334
++EE+ L + +K+AK E+ V + + + ++ + L ELE + +
Sbjct: 2183 GIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQES 2242
Query: 335 ECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESP 394
E E +EE + + R+ G + E E +K+ + +E +
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEG----EEKQVEKEEEEKKK-KKKEKKKE 2297
Query: 395 DITHQKRVFETVRNINQVVKQRSLT 419
++ ++ VFE I + SL+
Sbjct: 2298 EVQEKEEVFEEKEEIMSEEETESLS 2322
Score = 34.3 bits (77), Expect = 0.57
Identities = 45/225 (20%), Positives = 92/225 (40%), Gaps = 23/225 (10%)
Query: 119 LEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFY 178
+E +E E + L K+ +E E EE+ E EEV + E ++E
Sbjct: 2220 VESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEE----- 2274
Query: 179 TSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTET 238
EE + E K E + + +Q+K + EE+ ++ E +TE+
Sbjct: 2275 ---GEEKQVE-------KEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEE----ETES 2320
Query: 239 ITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKA 298
++ EE+E++ + + R+ + +L ++ + R +E + +L + + +A
Sbjct: 2321 LSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRGVPHGKGRA 2380
Query: 299 KACAVENEELVQHLGAAKDAQRQLTAELRE----LEDKYAECMEM 339
V L + + A + + + + E EDK A +E+
Sbjct: 2381 IRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWEDKKATVVEI 2425
>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sapiens]
Length = 1116
Score = 59.7 bits (143), Expect = 1e-08
Identities = 128/629 (20%), Positives = 239/629 (37%), Gaps = 104/629 (16%)
Query: 72 TPLISPDANIDLTTEQIE------ETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKE-- 123
T L++ ++ T Q E LK L E+ + +T ++DA+ LEEKE
Sbjct: 480 TELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQT--EVDALRLRLEEKETM 537
Query: 124 -------------------------RD-LELAARIGQSLLKKNKTLTERNELLEEQVEHI 157
+D L++ R L KK + L E+ E+Q+ +
Sbjct: 538 LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSL 597
Query: 158 REEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKL 217
+E V L+ + + D L A E E LK + +D+ +K L
Sbjct: 598 KERVKSLQADTTNTDTALTTLEEALAEKER---TIERLKEQRDRDEREKQEEIDNYKKDL 654
Query: 218 KDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKE---LRDANVQIASISEEL---- 270
KDL+E+ +L+ + S+ + + +E L + +K+ L+ + + EE
Sbjct: 655 KDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKME 714
Query: 271 --AKKTEDAA-------RQQEEITHLLSQIV---DLQKKAKACAVENEELVQHLGAAKDA 318
KK +AA + I HL +I D KA+A E+++ + K+
Sbjct: 715 SQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKND 774
Query: 319 QRQLTAEL-RELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAE 377
+ + AEL R+++D+ + + H+ Q E K ++ M RR +L DS
Sbjct: 775 KDKKIAELERQVKDQNKKVANLKHKEQVEKK--KSAQMLEEARRREDNLN----DSSQQL 828
Query: 378 IEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSL 437
+ +K+ ++EE E E +R Q+ +R + + +N + L
Sbjct: 829 QDSLRKKDDRIEELE-----------EALRESVQITAEREMVLAQEESARTNAEKQVEEL 877
Query: 438 LSSCVSTPRSSFYGSDIGNVVLDNKTNSII-LETEAADLGNDERS--------KKPGTPG 488
L + + + L + S+ ET +L + R K+
Sbjct: 878 LMAMEKVKQE----LESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLA 933
Query: 489 TPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTPTESIMSLG 548
D AL LS ++ E + E++R +Q+L ++ T++ M L
Sbjct: 934 AISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQ----------TQNRMKLM 983
Query: 549 THSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVV 608
+ E F + ++ P QI++PL +L HL + R ++
Sbjct: 984 ADN--YEDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLI 1041
Query: 609 TKGF---RTLDVDLDEVYCLNDFEEDDTG 634
+G + ++D D+ N+ ++ G
Sbjct: 1042 LRGLTPPASYNLDDDQAAWENELQKMTRG 1070
Score = 48.5 bits (114), Expect = 3e-05
Identities = 55/280 (19%), Positives = 107/280 (38%), Gaps = 46/280 (16%)
Query: 112 IDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMK 171
I ++ R L + E ++++ G ++ + ++ E+ + ++ +V QL+ ELS K
Sbjct: 391 ISSMERGLRDLEEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSK 450
Query: 172 DELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEA 231
+ + L+KK L+ E ++ E
Sbjct: 451 EA-----------------------------------QWEELKKKAAGLQAEIGQVKQEL 475
Query: 232 SQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQI 291
S+ TE + + K + L N + D+ I + E L K + AA Q E+ L ++
Sbjct: 476 SRKDTELLALQTKLETLTN----QFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRL 531
Query: 292 VD----LQKKAKACAVENEELVQHLGAAKDAQRQLTAELRE---LEDKYAECMEMLHEAQ 344
+ L KK K EE G D + L + R+ L+ K E L + +
Sbjct: 532 EEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKE 591
Query: 345 EELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRK 384
+++ +L+ + L ++ AE E T+ +
Sbjct: 592 KQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIER 631
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 59.7 bits (143), Expect = 1e-08
Identities = 128/629 (20%), Positives = 239/629 (37%), Gaps = 104/629 (16%)
Query: 72 TPLISPDANIDLTTEQIE------ETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKE-- 123
T L++ ++ T Q E LK L E+ + +T ++DA+ LEEKE
Sbjct: 452 TELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQT--EVDALRLRLEEKETM 509
Query: 124 -------------------------RD-LELAARIGQSLLKKNKTLTERNELLEEQVEHI 157
+D L++ R L KK + L E+ E+Q+ +
Sbjct: 510 LNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSL 569
Query: 158 REEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKL 217
+E V L+ + + D L A E E LK + +D+ +K L
Sbjct: 570 KERVKSLQADTTNTDTALTTLEEALAEKER---TIERLKEQRDRDEREKQEEIDNYKKDL 626
Query: 218 KDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKE---LRDANVQIASISEEL---- 270
KDL+E+ +L+ + S+ + + +E L + +K+ L+ + + EE
Sbjct: 627 KDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKME 686
Query: 271 --AKKTEDAA-------RQQEEITHLLSQIV---DLQKKAKACAVENEELVQHLGAAKDA 318
KK +AA + I HL +I D KA+A E+++ + K+
Sbjct: 687 SQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKND 746
Query: 319 QRQLTAEL-RELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAE 377
+ + AEL R+++D+ + + H+ Q E K ++ M RR +L DS
Sbjct: 747 KDKKIAELERQVKDQNKKVANLKHKEQVEKK--KSAQMLEEARRREDNLN----DSSQQL 800
Query: 378 IEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSL 437
+ +K+ ++EE E E +R Q+ +R + + +N + L
Sbjct: 801 QDSLRKKDDRIEELE-----------EALRESVQITAEREMVLAQEESARTNAEKQVEEL 849
Query: 438 LSSCVSTPRSSFYGSDIGNVVLDNKTNSII-LETEAADLGNDERS--------KKPGTPG 488
L + + + L + S+ ET +L + R K+
Sbjct: 850 LMAMEKVKQE----LESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLA 905
Query: 489 TPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSLTPTESIMSLG 548
D AL LS ++ E + E++R +Q+L ++ T++ M L
Sbjct: 906 AISEKDANIALLELSSSKKKTQEEVAALKREKDRLVQQLKQQ----------TQNRMKLM 955
Query: 549 THSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVV 608
+ E F + ++ P QI++PL +L HL + R ++
Sbjct: 956 ADN--YEDDHFKSSHSNQTNHKPSPDQIIQPLLELDQNRSKLKLYIGHLTTLCHDRDPLI 1013
Query: 609 TKGF---RTLDVDLDEVYCLNDFEEDDTG 634
+G + ++D D+ N+ ++ G
Sbjct: 1014 LRGLTPPASYNLDDDQAAWENELQKMTRG 1042
Score = 50.1 bits (118), Expect = 1e-05
Identities = 56/250 (22%), Positives = 109/250 (43%), Gaps = 23/250 (9%)
Query: 101 RVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREE 160
R+ +T N D + L E + L+A+ + ++ + L E E V H+
Sbjct: 294 RIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEA----EMHVHHLESL 349
Query: 161 VSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDL 220
+ Q E SM E + A +S T ++ +S S S+++ L+DL
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKIS--------SMERGLRDL 401
Query: 221 EEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQ 280
EEE +L+S + L TE E K+ ++ K +++ +I + +EL++K +
Sbjct: 402 EEEIQMLKSNGA-LSTEEREEEMKQMEVYRSHSKFMKN---KIGQVKQELSRKDTELLAL 457
Query: 281 QEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEML 340
Q ++ L +Q D ++ E L + L A + L E+ L + E ML
Sbjct: 458 QTKLETLTNQFSDSKQHI-------EVLKESLTAKEQRAAILQTEVDALRLRLEEKETML 510
Query: 341 HEAQEELKNL 350
++ ++++++
Sbjct: 511 NKKTKQIQDM 520
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 59.7 bits (143), Expect = 1e-08
Identities = 71/323 (21%), Positives = 142/323 (43%), Gaps = 44/323 (13%)
Query: 82 DLTTEQIEETLKYFLL---CAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLK 138
DL TE E LK L C + + + + +T L+ ++ D+ + + +LK
Sbjct: 501 DLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLK 560
Query: 139 KNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRN 198
+ + L E L ++E++REE+ Q R E+ K + + E C+ K+
Sbjct: 561 QIENLQETETQLRNELEYVREELKQKRDEVKCKLD------------KSEENCNNLRKQV 608
Query: 199 ESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRD 258
E+ + K +++L++EN L+ + + + YE K VN EL
Sbjct: 609 ENKN------------KYIEELQQENKALKKKGTAESKQLNVYEIK----VNKLELELES 652
Query: 259 ANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDA 318
A + I++ K+ ED +E +LL ++ +KAK A E +L + + K
Sbjct: 653 AKQKFGEITDTYQKEIEDKKISEE---NLLEEV----EKAKVIADEAVKLQKEID--KRC 703
Query: 319 QRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEI 378
Q ++ + +E + +++ E EL ++K ++ R + L +L AE+
Sbjct: 704 QHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIEL---SNLKAEL 760
Query: 379 EGTMRKELQLEEAESPDITHQKR 401
+++K+L++E E + + +
Sbjct: 761 L-SVKKQLEIEREEKEKLKREAK 782
Score = 50.8 bits (120), Expect = 6e-06
Identities = 63/311 (20%), Positives = 120/311 (38%), Gaps = 34/311 (10%)
Query: 120 EEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYT 179
E+ LE + + L+K+N LL+E E+ + +E ++E Q Y
Sbjct: 156 EKVSLKLEEGIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYE---REETRQVYM 212
Query: 180 SAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEE-NVVLRSEASQLKTET 238
E L+ +S ++ +F L +K++ LE+E + + Q+
Sbjct: 213 DLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLL 272
Query: 239 ITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKA 298
I EKE ++ D L ++ ++ + E+ ++E+ + E+ HL ++ D++
Sbjct: 273 IQITEKENKM-KDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSL 331
Query: 299 KACAVENEELVQHLGAAKDAQRQLTAE------------------LRELEDKYAECMEML 340
+ + L + L A QLT E + E E E+L
Sbjct: 332 QRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELL 391
Query: 341 HEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEE-----AESPD 395
Q+ L+ ++ T + S L M L T KE++LEE E
Sbjct: 392 RTEQQRLEKNEDQLKILTMELQKKSSELEEMTKL------TNNKEVELEELKKVLGEKET 445
Query: 396 ITHQKRVFETV 406
+ ++ + FE +
Sbjct: 446 LLYENKQFEKI 456
Score = 47.0 bits (110), Expect = 8e-05
Identities = 80/358 (22%), Positives = 144/358 (40%), Gaps = 70/358 (19%)
Query: 104 QMTKTYNDIDAVTRLLEE---KERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREE 160
Q+T+ N + +T LLEE K LE ++ LK++ E+ L +++E I+
Sbjct: 274 QITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQS---IEKQHHLTKELEDIKVS 330
Query: 161 VSQLRHELSMKDELLQFYTSA----AEESEPE--------------------SVCSTP-L 195
+ + +E LQ T EE E + +VCS L
Sbjct: 331 LQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEEL 390
Query: 196 KRNESSSSVQNYFHLD----SLQKKLKDLEEENVVLRSEASQLKT--------ETITYEE 243
R E +N L LQKK +LEE + ++ +L+ ET+ YE
Sbjct: 391 LRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYEN 450
Query: 244 KEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEIT----HLLSQIVDLQKKAK 299
K+ + + +EL+ ++ + + K+ D Q IT + ++ DL+ + +
Sbjct: 451 KQFEKI---AEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDLKTELE 507
Query: 300 ACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTT 359
++N EL H +L+ E +EL + ++ L QE++ N NK
Sbjct: 508 NEKLKNTELTSHC-------NKLSLENKELTQETSDMTLELKNQQEDINN--NKKQEERM 558
Query: 360 SRRYHSLGLFPMDSLAAEIEGTMRKELQL--EEAESPDITHQKRVFETVRNINQVVKQ 415
++ +L E E +R EL+ EE + + ++ ++ N N + KQ
Sbjct: 559 LKQIENL---------QETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQ 607
Score = 43.1 bits (100), Expect = 0.001
Identities = 64/299 (21%), Positives = 121/299 (40%), Gaps = 46/299 (15%)
Query: 127 ELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSM-------KDELLQFYT 179
EL + S L+ + L E E ++ + ++E++ ++S+ K+ ++ T
Sbjct: 227 ELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLT 286
Query: 180 SAAEESEP---ESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEAS---- 232
EES + T L+ S++ HL K+LE+ V L+ S
Sbjct: 287 FLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLT------KELEDIKVSLQRSVSTQKA 340
Query: 233 -----QLKTETITY--EEKEQQLVNDCVKE------LRDANVQIASISEELAKKTEDAAR 279
Q+ T+TI EEKE Q+ + + + S+ E L + + +
Sbjct: 341 LEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEK 400
Query: 280 QQEEITHLL-------SQIVDLQKKAKACAVENEELVQHLGAAKDA---QRQLTAELREL 329
++++ L S++ ++ K VE EEL + LG + +Q EL
Sbjct: 401 NEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYENKQFEKIAEEL 460
Query: 330 EDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQL 388
+ E + +L ++E+ +L + TTS +Y+S + L E+E K +L
Sbjct: 461 KGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSK---EVKDLKTELENEKLKNTEL 516
Score = 30.8 bits (68), Expect = 6.3
Identities = 62/305 (20%), Positives = 117/305 (38%), Gaps = 47/305 (15%)
Query: 139 KNKTLTERNELLE-EQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKR 197
++K ++E N L E E+ + I +E +L+ E+ + + E V +
Sbjct: 669 EDKKISEENLLEEVEKAKVIADEAVKLQKEIDKR----------CQHKIAEMVALMEKHK 718
Query: 198 NESSSSVQNYFHLDSLQKKLKDLEEENVVLRS----EASQLKTETITYEEKEQQLVNDCV 253
++ ++ DS K E+E LR+ E S LK E ++ +++ + +
Sbjct: 719 HQYDKIIEER---DSELGLYKSKEQEQSSLRASLEIELSNLKAELLSVKKQLEIEREEKE 775
Query: 254 KELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLG 313
K R+A A++ E+ KKT+ + EI L D + N V H G
Sbjct: 776 KLKREAKENTATLKEKKDKKTQTFLLETPEIYWKL----DSKAVPSQTVSRNFTSVDH-G 830
Query: 314 AAKDAQRQL-TAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMD 372
+KD + L T+ L + + + +L+ N +P S++ + F D
Sbjct: 831 ISKDKRDYLWTSAKNTLSTPLPKAYTVKTPTKPKLQQRENLNIPIEESKKKRKMA-FEFD 889
Query: 373 SLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNI---------NQVVKQRSLTPSPM 423
+ + +E+ D+ ET++ + + VK PS +
Sbjct: 890 -------------INSDSSETTDLLSMVSEEETLKTLYRNNNPPASHLCVKTPKKAPSSL 936
Query: 424 NIPGS 428
PGS
Sbjct: 937 TTPGS 941
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 59.7 bits (143), Expect = 1e-08
Identities = 74/324 (22%), Positives = 135/324 (41%), Gaps = 57/324 (17%)
Query: 118 LLEEKERDLELAARIGQSLLKKNKTLTERNEL-----------LEEQVEHIREEVSQLRH 166
L EEK+RD+ + +SL + + E L L+++ +H+R+EV L
Sbjct: 257 LKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEG 316
Query: 167 ELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHL----DSLQKKLKDLEE 222
+L + E Q + ++E + + R + + V+ L + L+++ K L+E
Sbjct: 317 KLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQE 376
Query: 223 ENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQE 282
+ LR + +L+ + ++E++L K L D E L KK E +Q+E
Sbjct: 377 QGERLRKQEQRLRKQEERLRKEEERLQKQ-EKRLWDQ-------EERLWKKEERLQKQEE 428
Query: 283 EITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHE 342
+ + +D Q C+ E+ L K + QL +++EL++K E E L
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFED------LNNEKKSALQLEQQVKELQEKLDE--EHLEA 480
Query: 343 AQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRV 402
A + + L + + +A EG + L EE E+P T
Sbjct: 481 ASHQNQQLETQ-----------------LSLVALPGEGDGGQHLDSEEEEAPRPT----- 518
Query: 403 FETVRNINQVVKQRSLTPSPMNIP 426
NI + ++ R T S M++P
Sbjct: 519 ----PNIPEDLESREATSSFMDLP 538
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 59.3 bits (142), Expect = 2e-08
Identities = 69/303 (22%), Positives = 141/303 (46%), Gaps = 39/303 (12%)
Query: 80 NIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEE-----KERDLELAA---- 130
N D ++++E+ K + L ++ + Q + T IDA + L+E K+R E+ A
Sbjct: 501 NYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLK 560
Query: 131 ---RIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHEL-SMKDELLQFYTSAAE--- 183
IG ++ + E +++E+ R +S+++ E+ +M Q ++ E
Sbjct: 561 DLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNK 620
Query: 184 ---ESEPE-SVCSTPLKRNESS-SSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTET 238
E+E E + C + ++E+ S+ Y L ++++K + LEE L E QL+ +
Sbjct: 621 KMEENEKELAACQLRISQHEAKIKSLTEY--LQNVEQKKRQLEESVDALSEELVQLRAQE 678
Query: 239 ITYE-EKE-----------QQLVNDCVKELRDANV-QIASISEELAKKTEDAARQQEEIT 285
+E EKE +Q V ++ R+ + QI+S+ +E+ K + Q++
Sbjct: 679 KVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQ 738
Query: 286 HLLSQIVDLQ---KKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHE 342
++ + L+ +K KA E + L +D + Q +L+ LE+ A+ ++ LH
Sbjct: 739 KMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHN 798
Query: 343 AQE 345
++
Sbjct: 799 LRK 801
Score = 30.8 bits (68), Expect = 6.3
Identities = 36/162 (22%), Positives = 71/162 (43%), Gaps = 29/162 (17%)
Query: 214 QKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKK 273
+KK + +E+N +LR+ L+ E + E +++ + + AN++ ++ +++
Sbjct: 341 KKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEK-ANLEAFTVDKDITLT 399
Query: 274 TE-------------DAARQ--QEEITHLLSQIVD----------LQKKAKACAVENEEL 308
+ DA R+ +EEI L Q+ D L +K K ++ EEL
Sbjct: 400 NDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEEL 459
Query: 309 VQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNL 350
L + + Q + AEL L+ + E + E + L+ L
Sbjct: 460 ---LASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEEL 498
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 59.3 bits (142), Expect = 2e-08
Identities = 78/356 (21%), Positives = 159/356 (44%), Gaps = 45/356 (12%)
Query: 81 IDLTTEQIEETLKYFLLCAERV-GQMTKTYNDIDAVTRLLEEKERD-----LELAARIGQ 134
I++T Q+E ++ E + G++ ++D R E+ERD L A + G+
Sbjct: 783 IEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDT-ERSQAEQERDAAARQLAQAEQEGK 841
Query: 135 SLLKKNKTLTER--NELLE----EQVEHIRE--------EVSQLRHELSMKDELLQFYTS 180
+ L++ K E+ N+L E E+ H +E E ++ E+ +K++ +
Sbjct: 842 TALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAI 901
Query: 181 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT 240
A+ E + + L + + + + L++L + K+L + + L +K + +
Sbjct: 902 QAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKL- 960
Query: 241 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA 300
KEQ+ +L++A ++ E + +D A QEE + LL +DLQK+
Sbjct: 961 ---KEQETTGILQTQLQEAQREL---KEAARQHRDDLAALQEESSSLLQDKMDLQKQV-- 1012
Query: 301 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS 360
E+L L A D+QR + +E+++K E E + Q+EL+ + +
Sbjct: 1013 -----EDLKSQLVAQDDSQRLVE---QEVQEKLRETQE-YNRIQKELEREKASLTLSLME 1063
Query: 361 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRVFETVRNINQVVKQR 416
+ L L DS+ + +R+++Q + E +++ Q + + Q VK++
Sbjct: 1064 KEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMEL------LRQEVKEK 1113
Score = 45.1 bits (105), Expect = 3e-04
Identities = 65/244 (26%), Positives = 111/244 (45%), Gaps = 42/244 (17%)
Query: 118 LLEEKERDLELA-ARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLR--------HEL 168
LL +++ ++ A AR QS+ + L+ L+ +V +R +L ++
Sbjct: 558 LLRQEQTEVTAALARAEQSIAE----LSSSENTLKTEVADLRAAAVKLSALNEALALDKV 613
Query: 169 SMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLR 228
+ +LLQ E E +SVCS R E++ +N +LQ L + E+ L
Sbjct: 614 GLNQQLLQL------EEENQSVCS----RMEAAEQARN-----ALQVDLAEAEKRREALW 658
Query: 229 SEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLL 288
+ + L+ + EE +L D LRD I EE+ KK ++ QQE T L
Sbjct: 659 EKNTHLEAQLQKAEEAGAELQAD----LRD----IQEEKEEIQKKLSESRHQQEAATTQL 710
Query: 289 SQI---VDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQE 345
Q+ Q++ A AV+ +E + AA + +L A R+ +D AE ++ L A+E
Sbjct: 711 EQLHQEAKRQEEVLARAVQEKEALVREKAALEV--RLQAVERDRQD-LAEQLQGLSSAKE 767
Query: 346 ELKN 349
L++
Sbjct: 768 LLES 771
Score = 45.1 bits (105), Expect = 3e-04
Identities = 65/297 (21%), Positives = 129/297 (43%), Gaps = 39/297 (13%)
Query: 101 RVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREE 160
+V Q ++ +T+ L E+E ++E Q L K+ + ELL ++ +E
Sbjct: 1412 KVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQE 1471
Query: 161 VSQLRHELSMKDE---LLQFYTSAAEESEPE-SVCSTPLKRNESSSSVQNYFHLDSLQKK 216
V + ++ ++ +L+ A +E E + +V ++ E Q + L+ +
Sbjct: 1472 VDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQR----NVLEHQ 1527
Query: 217 LKDLEEENVVLRSEASQLKT--------ETITYEEKEQQLVNDCVKEL-RDANVQIASIS 267
L +LE+++ ++ S+ Q++ E + E +E +C ++L ++ Q +
Sbjct: 1528 LLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQR 1587
Query: 268 EELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAK----DAQRQ-- 321
L T D + +E+ SQI DL+ + A E +E Q + + + + QRQ
Sbjct: 1588 VALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKE 1647
Query: 322 -LTAELRE--------------LEDKYAECMEMLHEAQEELK-NLRNKTMPNTTSRR 362
LT +L LED+ ++L E E++K +LR + TT R+
Sbjct: 1648 HLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQ 1704
Score = 44.3 bits (103), Expect = 6e-04
Identities = 62/292 (21%), Positives = 117/292 (40%), Gaps = 60/292 (20%)
Query: 113 DAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKD 172
+AV L + +DL + L + + L ER E + + E+ L+ +LS
Sbjct: 1239 EAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQ 1298
Query: 173 ELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQK----------------- 215
E + E + S+ S ++ +E+ +S+Q+ LQ+
Sbjct: 1299 E-----EKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENL 1353
Query: 216 --KLKDLEEENVVLRSEAS----------------QLKTETITYEEKEQQLVNDCVKELR 257
+++ L+ V R++AS +LK E + E + Q + + EL+
Sbjct: 1354 TAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQE-QGELK 1412
Query: 258 DANVQIASISEELAKKTEDAARQQEEITHLLSQIVDL--QKKAKACAVE----------- 304
A Q ++ E LA T+ A ++EE+ L QI +L Q++ + A+E
Sbjct: 1413 VA--QGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQ 1470
Query: 305 ----NEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRN 352
+E +Q L + L ++E E K E + E +++ + RN
Sbjct: 1471 EVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRN 1522
Score = 44.3 bits (103), Expect = 6e-04
Identities = 75/384 (19%), Positives = 152/384 (39%), Gaps = 54/384 (14%)
Query: 47 LEEQLPHYKLRADTIYGYD-HDDWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQM 105
LEE+ + ++ I+ + H L L D + EQIEE Q
Sbjct: 1597 LEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEEL------------QR 1644
Query: 106 TKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLR 165
K + +T+ LE ++++L L Q L + T + ++LEE +E I+ + +
Sbjct: 1645 QKEH-----LTQDLERRDQELMLQKERIQVLEDQR---TRQTKILEEDLEQIKLSLRERG 1696
Query: 166 HELSMKDELLQFYT------SAAEESEPESVCSTPLKRNESSSSVQNYFH-----LDSLQ 214
EL+ + +L+Q S A+ E + + + Q + H D L+
Sbjct: 1697 RELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLE 1756
Query: 215 KKLKDL--------------EEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDAN 260
++L+ L E+E VVL+ + + + + E+ Q +++ + L +
Sbjct: 1757 QQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRD 1816
Query: 261 VQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENE-ELVQHLGAAKDAQ 319
++ E L ++ + A Q+E + + ++A E EL H A+ +
Sbjct: 1817 QEL----EALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLE 1872
Query: 320 RQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIE 379
+L E R ++ ++ E++E+ K L + H + + + +
Sbjct: 1873 EELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQ 1932
Query: 380 GTMR---KELQLEEAESPDITHQK 400
++ +EL+ AES HQ+
Sbjct: 1933 AVLKERDQELEALRAESQSSRHQE 1956
Score = 39.7 bits (91), Expect = 0.014
Identities = 54/282 (19%), Positives = 108/282 (38%), Gaps = 37/282 (13%)
Query: 103 GQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS 162
G++ + + + + EE + LE+ + L + N L + + + Q E +EE+
Sbjct: 456 GEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELH 515
Query: 163 QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYF----------HLDS 212
E E+L + ES E + L+ SS ++ L
Sbjct: 516 LAVRERERLQEMLMGLEAKQSESLSELIT---LREALESSHLEGELLRQEQTEVTAALAR 572
Query: 213 LQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQL------VNDCVKELRDANVQIASI 266
++ + +L L++E + L+ + + L +N + +L + N + S
Sbjct: 573 AEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSR 632
Query: 267 SE-----------ELAKKTEDAARQQEEITHLLSQI-------VDLQKKAKACAVENEEL 308
E +LA+ + E+ THL +Q+ +LQ + E EE+
Sbjct: 633 MEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEI 692
Query: 309 VQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNL 350
+ L ++ Q T +L +L + E+L A +E + L
Sbjct: 693 QKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEAL 734
Score = 38.9 bits (89), Expect = 0.023
Identities = 67/304 (22%), Positives = 127/304 (41%), Gaps = 25/304 (8%)
Query: 120 EEKERDLELAARIGQSLLKKNKTL-TERNELLEEQVEHIRE--EVSQLRHELSMKDE--- 173
EE++ +L LA R + L + L +++E L E + +RE E S L EL +++
Sbjct: 508 EEQQEELHLAVRERERLQEMLMGLEAKQSESLSELIT-LREALESSHLEGELLRQEQTEV 566
Query: 174 ---LLQFYTSAAEESEPESVCSTPLKRNESS----SSVQNYFHLDS--LQKKLKDLEEEN 224
L + S AE S E+ T + ++ S++ LD L ++L LEEEN
Sbjct: 567 TAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEEN 626
Query: 225 --VVLRSEASQLKTETITYEEKEQQLVNDCVKELRD-ANVQIASISEELAKKTEDAARQQ 281
V R EA++ + + E + + + E Q+ E A+ D Q
Sbjct: 627 QSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQ 686
Query: 282 EEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLH 341
EE + ++ + + + +A + E+L Q ++ + E L + A L
Sbjct: 687 EEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQ 746
Query: 342 EAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTM-RKELQLEEAESPDITHQK 400
+ + ++L + ++++ LF + IE T + E+Q++ +T K
Sbjct: 747 AVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQ-----TVTQAK 801
Query: 401 RVFE 404
V +
Sbjct: 802 EVIQ 805
Score = 38.9 bits (89), Expect = 0.023
Identities = 73/367 (19%), Positives = 143/367 (38%), Gaps = 38/367 (10%)
Query: 118 LLEEKE--RDLELAARIGQSLLKK----NKTLTERNELLEEQVE----HIREEVSQLRHE 167
LLE+ E R LE + Q+ L ++ L E + E +++ +E+V QL+
Sbjct: 1984 LLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQA 2043
Query: 168 LSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVL 227
L+ +DE L+ + E E + L + + +Q +K+ E E +
Sbjct: 2044 LAQRDEELR------HQQEREQLLEKSLAQRVQENMIQ--------EKQNLGQEREEEEI 2089
Query: 228 RSEASQLKTETITYEEKEQQLVNDCVKELRDA----NVQIASISEELAKKTEDAARQQEE 283
R ++ +T +KEQ+++ ELR+ N++ S + + E + +
Sbjct: 2090 RGLHQSVRELQLTLAQKEQEIL-----ELRETQQRNNLEALPHSHKTSPMEEQSLKLDSL 2144
Query: 284 ITHLLSQIVDLQ---KKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEML 340
L ++ LQ ++ +A +E E Q L + + + L+E+ +
Sbjct: 2145 EPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLER 2204
Query: 341 HEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIE-GTMRKELQLEEAE-SPDITH 398
Q+ L++ T R HS G L + E G E+ EAE SPD
Sbjct: 2205 DSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGME 2264
Query: 399 QKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVV 458
++ + + ++ Q V + + S + S + + R + + G++
Sbjct: 2265 KQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQAGSLE 2324
Query: 459 LDNKTNS 465
+ T S
Sbjct: 2325 ISKATAS 2331
Score = 37.4 bits (85), Expect = 0.067
Identities = 59/269 (21%), Positives = 116/269 (43%), Gaps = 28/269 (10%)
Query: 97 LCAERVGQMTKTYNDIDAVTRLLEEKERDLE--------------LAARIGQSLLKKNKT 142
L E GQ + +T LEE+ ++L+ + AR Q ++ K+
Sbjct: 1575 LIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKS 1634
Query: 143 LTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSS 202
E+ E L+ Q EH+ +++ + EL ++ E +Q + + + L++ + S
Sbjct: 1635 QREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLED--QRTRQTKILEEDLEQIKLSL 1692
Query: 203 SVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQ 262
+ Q + EE +++ L+ + +KE+++ +C +E +
Sbjct: 1693 RERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEV--ECQQEHIH---E 1747
Query: 263 IASISEELAKKTEDAARQQEEITHLLSQ----IVDLQKKAKACAVENEELVQHLGAAKD- 317
+ + ++L ++ + R+ E + LLSQ IV LQ++ + + E Q L + D
Sbjct: 1748 LQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDE 1807
Query: 318 AQRQLTAELRELEDKYAECMEMLHEAQEE 346
AQR L +ELE E + + QEE
Sbjct: 1808 AQRALAQRDQELEALQQE--QQQAQGQEE 1834
Score = 32.0 bits (71), Expect = 2.8
Identities = 88/454 (19%), Positives = 171/454 (37%), Gaps = 49/454 (10%)
Query: 120 EEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYT 179
E ++R EL+A + QS ++NE E+ ++ +RE V L + EL++
Sbjct: 280 ELQDRVTELSALLTQS--------QKQNEDYEKMIKALRETVEILE---TNHTELMEHEA 328
Query: 180 SAAEESEPESVCSTPLKRN------------ESSSSVQNYFHLDSLQKKLKDLEEENVVL 227
S + ++ E + + ++ S +N LDS D ++ + L
Sbjct: 329 SLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKAL 388
Query: 228 RSEASQLKTETITYEEKEQQLVN--DCVKELRDANVQIASISEELAKKTEDAARQQEEIT 285
S L ++ QQL + V L+ + Q + L ++ + +++
Sbjct: 389 TLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDT-- 446
Query: 286 HLLSQIVDLQKKAKACAVENE-------ELVQHLGAAKDAQRQLTAELRELEDKYAECME 338
L Q VDLQ + + + E E EL Q L + +L EL+ +
Sbjct: 447 -LAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQG 505
Query: 339 MLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDI-T 397
E QEEL + + + +GL S + T+R+ L+ E +
Sbjct: 506 QKEEQQEEL----HLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQ 561
Query: 398 HQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNV 457
Q V + Q + + S + + + ++ +A LS+ G + +
Sbjct: 562 EQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVK-LSALNEALALDKVGLNQQLL 620
Query: 458 VLDNKTNSIILETEAADLGND-------ERSKKPGTPGTPGSHDLETALRRLSLRRENYL 510
L+ + S+ EAA+ + E K+ +H LE L++
Sbjct: 621 QLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTH-LEAQLQKAEEAGAELQ 679
Query: 511 SERRFFEEEQERKLQELAEKGELRSGSLTPTESI 544
++ R +EE+E ++L+E + + T E +
Sbjct: 680 ADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQL 713
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 59.3 bits (142), Expect = 2e-08
Identities = 74/368 (20%), Positives = 151/368 (41%), Gaps = 45/368 (12%)
Query: 86 EQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTE 145
EQI+ + + +M +D+ + + + + +LE R + L + KT E
Sbjct: 1209 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEE 1268
Query: 146 RNELL----EEQVEHIREEVSQLRHELSMKDELL-------QFYTSAAEESEPESVCSTP 194
+ L Q ++ E + +L KD L+ Q +T EE + +
Sbjct: 1269 EQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIK 1328
Query: 195 LKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLR-------SEASQLKT----ETITYEE 243
K + + + D L+++ ++ +E L+ SE +Q +T + I E
Sbjct: 1329 AKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTE 1388
Query: 244 KEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAV 303
+ ++ + L+DA + +++ + A + R Q E+ L+ +D+++ ACA
Sbjct: 1389 ELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLM---IDVERTNAACAA 1445
Query: 304 EN-----------------EELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEE 346
+ EE L A++ R L+ EL ++++ Y E ++ L + E
Sbjct: 1446 LDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRE 1505
Query: 347 LKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQ--LEEAESPDITHQKRVFE 404
KNL+ + T + ++ + ++E + ELQ LEEAE+ + ++
Sbjct: 1506 NKNLQQEISDLTEQIAEGGKRIHELEKIKKQVE-QEKSELQAALEEAEASLEHEEGKILR 1564
Query: 405 TVRNINQV 412
+NQV
Sbjct: 1565 IQLELNQV 1572
Score = 50.8 bits (120), Expect = 6e-06
Identities = 75/313 (23%), Positives = 136/313 (43%), Gaps = 41/313 (13%)
Query: 37 DLPEVEIISLLEEQLPHY-KLRADTIYGYDHDDWLHTPLISPDANIDLTTE-QIEETLKY 94
DL E+EI QL H ++ A+ + Y + T I D + L + +E LK
Sbjct: 1625 DLNEMEI------QLNHANRMAAEALRNYRN-----TQAILKDTQLHLDDALRSQEDLKE 1673
Query: 95 FLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQV 154
L ER + + +I+ + LE+ ER ++A + ++ + L +N L
Sbjct: 1674 QLAMVERRANLLQA--EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTK 1731
Query: 155 EHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQ 214
+ + ++SQ++ E+ ++++Q +A EE +++ + E HL+ ++
Sbjct: 1732 KKLETDISQIQGEM---EDIIQEARNA-EEKAKKAITDAAMMAEELKKEQDTSAHLERMK 1787
Query: 215 KKL----KDL-----EEENVVLRSEASQL-KTETITYE-----EKEQQLVNDCVKELRDA 259
K L KDL E E + L+ Q+ K E E E EQ+ + VK LR
Sbjct: 1788 KNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKH 1847
Query: 260 NVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQ 319
++ +EL +TE+ ++ I L + LQ K K+ + EE +
Sbjct: 1848 ERKV----KELTYQTEE---DRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKF 1900
Query: 320 RQLTAELRELEDK 332
R++ EL E E++
Sbjct: 1901 RRIQHELEEAEER 1913
Score = 48.1 bits (113), Expect = 4e-05
Identities = 62/278 (22%), Positives = 113/278 (40%), Gaps = 32/278 (11%)
Query: 68 DWLHTPLISPDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLE 127
D L I +A I TE+ E+ + + AE + K ++ + + +++ E L
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEE---INAELTAKKRKLEDECSELKKDIDDLELTLA 966
Query: 128 LAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLR--HELSMKDELLQFYTSAAEES 185
+ + K K LTE L+E + + +E L+ H+ ++ D LQ AEE
Sbjct: 967 KVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD--LQ-----AEED 1019
Query: 186 EPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKE 245
+ ++ +K + ++ L+ +K DLE L + + T+ E +
Sbjct: 1020 KVNTLTKAKIKLEQQVDDLEG--SLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDK 1077
Query: 246 QQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVEN 305
QQL E+L KK + + Q +I + + LQKK K
Sbjct: 1078 QQL------------------DEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARI 1119
Query: 306 EELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEA 343
EEL + + A + ++ + + +L + E E L EA
Sbjct: 1120 EELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEA 1157
Score = 48.1 bits (113), Expect = 4e-05
Identities = 68/331 (20%), Positives = 128/331 (38%), Gaps = 43/331 (12%)
Query: 86 EQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTE 145
E ++TL ++V +TK ++ + +++ E LE +I L + + L
Sbjct: 1005 EAHQQTLDDLQAEEDKVNTLTKAKIKLE---QQVDDLEGSLEQEKKIRMDLERAKRKLEG 1061
Query: 146 RNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQ 205
+L +E I + QL +L K+ + S E+ E + +Q
Sbjct: 1062 DLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIED--------------EQALGMQ 1107
Query: 206 NYFHLDSLQKKLKDLEEENVVLRS------------------------EASQLKTETITY 241
+ LQ ++++LEEE R+ EA + I
Sbjct: 1108 LQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEM 1167
Query: 242 EEKEQQLVNDCVKELRDANVQIASISEELAKKTEDA-ARQQEEITHLLSQIVDLQKKAKA 300
+K + ++L +A +Q + + L KK D+ A E+I +L L+K+
Sbjct: 1168 NKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSE 1227
Query: 301 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS 360
+E ++L ++ A+ L R LED+ +E E Q + +L + T
Sbjct: 1228 MKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTE 1287
Query: 361 RRYHSLGLFPMDSLAAEI-EGTMRKELQLEE 390
+S L D+L +++ G Q+EE
Sbjct: 1288 SGEYSRQLDEKDTLVSQLSRGKQAFTQQIEE 1318
Score = 43.5 bits (101), Expect = 0.001
Identities = 52/275 (18%), Positives = 105/275 (38%), Gaps = 28/275 (10%)
Query: 104 QMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVS- 162
Q+ K ++ A +EE E ++E K+ L+ E + E++E S
Sbjct: 1107 QLQKKIKELQA---RIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSA 1163
Query: 163 QLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEE 222
Q+ + E + E + + L++ + S + +D+LQ+ + LE+
Sbjct: 1164 QIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEK 1223
Query: 223 ENVVLRSE----ASQLKT--------------------ETITYEEKEQQLVNDCVKELRD 258
E ++ E AS ++T E T EE++Q+L+ND +
Sbjct: 1224 EKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRAR 1283
Query: 259 ANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDA 318
+ S +L +K ++ QI +L+++ + L L +++
Sbjct: 1284 LQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHD 1343
Query: 319 QRQLTAELRELEDKYAECMEMLHEAQEELKNLRNK 353
L + E ++ AE + +A E+ R K
Sbjct: 1344 CDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTK 1378
Score = 42.7 bits (99), Expect = 0.002
Identities = 50/249 (20%), Positives = 102/249 (40%), Gaps = 36/249 (14%)
Query: 115 VTRLLEEKERDLELAARIGQSLLKKNKT-----LTERNEL--LEEQVE-HIREEVSQLRH 166
V R + EK+ +++ R +++ ++ + RN+ L++++E + E QL H
Sbjct: 1576 VDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNH 1635
Query: 167 ELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVV 226
M E L+ Y RN + HLD + +DL+E+ +
Sbjct: 1636 ANRMAAEALRNY------------------RNTQAILKDTQLHLDDALRSQEDLKEQLAM 1677
Query: 227 LRSEASQLKTE----TITYEEKE------QQLVNDCVKELRDANVQIASISEELAKKTED 276
+ A+ L+ E T E+ E +Q + D + ++ + Q S+ K D
Sbjct: 1678 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737
Query: 277 AARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAEC 336
++ Q E+ ++ + + ++KAK + + + L +D L + LE +
Sbjct: 1738 ISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1797
Query: 337 MEMLHEAQE 345
L EA++
Sbjct: 1798 QHRLDEAEQ 1806
Score = 40.0 bits (92), Expect = 0.010
Identities = 100/480 (20%), Positives = 181/480 (37%), Gaps = 82/480 (17%)
Query: 82 DLTTEQIEET------LKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIG-- 133
DL EQ EE L+ + A +T + DA+ R E +E +LA R+
Sbjct: 1345 DLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDA 1404
Query: 134 ----QSLLKKNKTLTERNELLEEQVEHIREEVSQ-------LRHELSMKDELLQFYTSAA 182
+++ K +L + + L+ +VE + +V + L + D++L +
Sbjct: 1405 EEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKC 1464
Query: 183 EESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYE 242
EE+ E S R+ S+ + + +L+ L+ EN L+ E S L TE I
Sbjct: 1465 EETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDL-TEQIAEG 1523
Query: 243 EKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA-- 300
K + K++ ++ + EE +A+ + EE L Q+ Q K++
Sbjct: 1524 GKRIHELEKIKKQVEQEKSELQAALEEA-----EASLEHEEGKILRIQLELNQVKSEVDR 1578
Query: 301 -CAVENEELVQ----HLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQE-ELKNLRNKT 354
A ++EE+ Q H+ + Q L AE+R D +M + E E++
Sbjct: 1579 KIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANR 1638
Query: 355 MPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEA--ESPDITHQKRVFETVRNINQV 412
M R Y + D+ +L L++A D+ Q + E N+ Q
Sbjct: 1639 MAAEALRNYRNTQAILKDT-----------QLHLDDALRSQEDLKEQLAMVERRANLLQ- 1686
Query: 413 VKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEA 472
+ + L ++ T RS +LD +L T+
Sbjct: 1687 -------------------AEIEELRATLEQTERSRKIAEQ---ELLDASERVQLLHTQN 1724
Query: 473 ADLGNDERSKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGE 532
L N ++ LET + ++ E+ + E R EE+ ++ + + A E
Sbjct: 1725 TSLINTKKK-------------LETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAE 1771
Score = 38.9 bits (89), Expect = 0.023
Identities = 34/147 (23%), Positives = 67/147 (45%), Gaps = 4/147 (2%)
Query: 207 YFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCV---KELRDANVQI 263
YF + L K + E+E ++ E + K E E K ++L V +E D +Q+
Sbjct: 837 YFKIKPLLKSA-ETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQV 895
Query: 264 ASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLT 323
+ ++ LA E + + L ++I ++ ++A+ N EL +D +L
Sbjct: 896 QAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELK 955
Query: 324 AELRELEDKYAECMEMLHEAQEELKNL 350
++ +LE A+ + H + ++KNL
Sbjct: 956 KDIDDLELTLAKVEKEKHATENKVKNL 982
Score = 37.4 bits (85), Expect = 0.067
Identities = 57/303 (18%), Positives = 118/303 (38%), Gaps = 44/303 (14%)
Query: 101 RVGQMTKTYNDIDAVTRLLEEKERDLELAARIG---QSLLKKNKTLTERNELLEEQVE-- 155
++ + K+ + + EE E+ E A+ + L +K TL + L+ QV+
Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
Query: 156 -----HIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHL 210
E QL + ++ T AE+ E +
Sbjct: 899 ADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINA-------------------- 938
Query: 211 DSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEEL 270
L K + LE+E L+ + L+ T+ EKE+ + VK L + ++A + E +
Sbjct: 939 -ELTAKKRKLEDECSELKKDIDDLEL-TLAKVEKEKHATENKVKNLTE---EMAGLDETI 993
Query: 271 AKKTEDAARQQEEITHLLSQIVDLQKKAKA---CAVENEELVQHLGAAKDAQRQLTAELR 327
AK T++ QE L + + K ++ E+ V L + + ++++ +L
Sbjct: 994 AKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLE 1053
Query: 328 ELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQ 387
+ K +++ E+ +++N + + + F M L ++IE +Q
Sbjct: 1054 RAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKE------FEMSGLQSKIEDEQALGMQ 1107
Query: 388 LEE 390
L++
Sbjct: 1108 LQK 1110
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 59.3 bits (142), Expect = 2e-08
Identities = 76/324 (23%), Positives = 138/324 (42%), Gaps = 57/324 (17%)
Query: 118 LLEEKERDLELAARIGQSLLK-KNK----------TLTERNELLEEQVEHIREEVSQLRH 166
L EEK+RD+ + +SL + KN+ +T E L+++ +H+R+EV L
Sbjct: 257 LKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEG 316
Query: 167 ELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHL----DSLQKKLKDLEE 222
+L + E Q + ++E + + R + V+ L + L+++ K L+E
Sbjct: 317 KLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQE 376
Query: 223 ENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQE 282
+ LR + +L+ + ++E++L K L D E L KK E +Q+E
Sbjct: 377 QGERLRKQEQRLRKQEERLRKEEERLQKQ-EKRLWDQ-------EERLWKKEERLQKQEE 428
Query: 283 EITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHE 342
+ + +D Q C+ E+ L K + QL +++EL++K E E L
Sbjct: 429 RLALSQNHKLDKQLAEPQCSFED------LNNEKKSALQLEQQVKELQEKLDE--EHLEA 480
Query: 343 AQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEEAESPDITHQKRV 402
A ++ + L + + +A EG + L EE E+P T
Sbjct: 481 ASQQNQQLETQ-----------------LSLVALPGEGDGGQHLDSEEEEAPRPT----- 518
Query: 403 FETVRNINQVVKQRSLTPSPMNIP 426
NI + ++ R T S M++P
Sbjct: 519 ----PNIPEDLESREATSSFMDLP 538
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 58.9 bits (141), Expect = 2e-08
Identities = 78/392 (19%), Positives = 160/392 (40%), Gaps = 44/392 (11%)
Query: 86 EQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTE 145
++ E +K + + + TK ++ + + EEK DL+ + + K L +
Sbjct: 690 QEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQ 749
Query: 146 RNELLEEQVEHIREE-------VSQLRHELSMKD-ELLQFYTSAAEESEPESVCSTPL-- 195
+ E E+Q++H+ E S + EL ++ +L + +E S+ + L
Sbjct: 750 QLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 809
Query: 196 ------KRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYE------- 242
+ +E + SVQ + KL EE+ +L S+ +L+ E
Sbjct: 810 LKEKFAEASEEAVSVQR--SMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKD 867
Query: 243 EKEQQLV-------NDCVKELR---DANVQIASISEELAKKTEDAARQQEEITHLLSQIV 292
E+E+QL+ ND + ++ D + Q+ +++EL K D Q ++T
Sbjct: 868 EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS 927
Query: 293 DLQKKAKACAVENEELVQ-----HLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEEL 347
LQK + V+ E+ Q H K+ +R+L+ +++E + +C E+ +A+ E
Sbjct: 928 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQEL--KARYER 985
Query: 348 KNLRNKTMPNTTSRRYHSLGLFPMDSL--AAEIEGTMRKELQLEEAESPDITHQKRVFET 405
KT + L D L A E + +EL+ ++ + +
Sbjct: 986 ATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDA 1045
Query: 406 VRNINQVVKQRSLTPSPMNIPGSNQSSAMNSL 437
++ + Q+ K+++ T + + + N L
Sbjct: 1046 MQIMEQMTKEKTETLASLEDTKQTNAKLQNEL 1077
Score = 50.1 bits (118), Expect = 1e-05
Identities = 61/283 (21%), Positives = 125/283 (44%), Gaps = 33/283 (11%)
Query: 120 EEKERDLELAARIGQSLLK---KNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQ 176
E K + E+ + ++LL K K E N L +++E +R++ + + + +D +
Sbjct: 989 ETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQI 1048
Query: 177 FYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKT 236
E++E + + N LQ +L L+E N+ E ++ K
Sbjct: 1049 MEQMTKEKTETLASLEDTKQTNAK------------LQNELDTLKENNLKNVEELNKSK- 1095
Query: 237 ETITYEEKEQQLVNDCVKELRDA----NVQIASISEELAKKTEDAARQQEEITHLLSQIV 292
E +T E ++ + ++ L+ A + Q++++ EE K E+ R ++E+T
Sbjct: 1096 ELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVT------- 1148
Query: 293 DLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRN 352
QK + +V N +L++ + E L+ + +L E EL+ LRN
Sbjct: 1149 SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRN 1208
Query: 353 KTM----PNTTSRRYHSLGLFPMDSLAAEIEGTMRK-ELQLEE 390
+ N +++ HS+ + ++S ++E ++ ELQL+E
Sbjct: 1209 EVTVLRGENASAKSLHSV-VQTLESDKVKLELKVKNLELQLKE 1250
Score = 43.9 bits (102), Expect = 7e-04
Identities = 76/389 (19%), Positives = 162/389 (41%), Gaps = 73/389 (18%)
Query: 77 PDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSL 136
P ++D++ ++E + + ++T+T + + +T L E E + ++L
Sbjct: 492 PAGDVDMSLSLLQE-----ISSLQEKLEVTRTDHQRE-ITSLKEHFGAREETHQKEIKAL 545
Query: 137 LKKNKTLTERNELLEEQVEHIREEVSQL-------------RHELSMKDELLQFYTSAAE 183
+ L++ NE L+ ++EH +E S + H+ +M++ + F
Sbjct: 546 YTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGT 605
Query: 184 ESEPESVCSTP--------------LKRNESSSSVQNYFHLDSLQKKL-KDLEEENVVLR 228
E+ + T L+ + S + +++L+ KL K ++E+ L
Sbjct: 606 ETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLE 665
Query: 229 SEASQLKTETITYEEKEQQLV--NDCVKELRDANVQIASISEELAKKTEDAARQQEEITH 286
+ S+L + ++Q LV D + +L++A +++ + E L K + + + T
Sbjct: 666 AIRSKLD------KAEDQHLVEMEDTLNKLQEAEIKVKEL-EVLQAKCNEQTKVIDNFTS 718
Query: 287 LL----SQIVDLQKKAKACA---VENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEM 339
L +++DL KA + E ++L Q L AA+ + L E K +
Sbjct: 719 QLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRE 778
Query: 340 LHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQL-----EEAESP 394
L + +L NL+ S ++++ T+ KELQ+ EA
Sbjct: 779 LQGRELKLTNLQENL------------------SEVSQVKETLEKELQILKEKFAEASEE 820
Query: 395 DITHQKRVFETVRNINQVVKQRSLTPSPM 423
++ Q+ + ETV ++Q +Q ++ S +
Sbjct: 821 AVSVQRSMQETVNKLHQKEEQFNMLSSDL 849
Score = 43.9 bits (102), Expect = 7e-04
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 15/209 (7%)
Query: 100 ERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIRE 159
+ V ++ K+ + + +EE +++E + ++ L E N L E++ R+
Sbjct: 1086 KNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRD 1145
Query: 160 EVS---QLRHELS-MKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQK 215
EV+ +L E S + ++LL+ ++ + L+++ S +S L
Sbjct: 1146 EVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSAL----LTEKDA 1201
Query: 216 KLKDLEEENVVLRSEASQLKT-----ETITYEEKEQQL-VNDCVKELRDANVQIASISEE 269
+L+ L E VLR E + K+ +T+ ++ + +L V + +L++ Q++S S
Sbjct: 1202 ELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGN 1261
Query: 270 L-AKKTEDAARQQEEITHLLSQIVDLQKK 297
+ ED Q+ +I L S IVDLQ+K
Sbjct: 1262 TDTQADEDERAQESQIDFLNSVIVDLQRK 1290
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 58.9 bits (141), Expect = 2e-08
Identities = 78/392 (19%), Positives = 160/392 (40%), Gaps = 44/392 (11%)
Query: 86 EQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTE 145
++ E +K + + + TK ++ + + EEK DL+ + + K L +
Sbjct: 725 QEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQ 784
Query: 146 RNELLEEQVEHIREE-------VSQLRHELSMKD-ELLQFYTSAAEESEPESVCSTPL-- 195
+ E E+Q++H+ E S + EL ++ +L + +E S+ + L
Sbjct: 785 QLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQI 844
Query: 196 ------KRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYE------- 242
+ +E + SVQ + KL EE+ +L S+ +L+ E
Sbjct: 845 LKEKFAEASEEAVSVQR--SMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKD 902
Query: 243 EKEQQLV-------NDCVKELR---DANVQIASISEELAKKTEDAARQQEEITHLLSQIV 292
E+E+QL+ ND + ++ D + Q+ +++EL K D Q ++T
Sbjct: 903 EREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS 962
Query: 293 DLQKKAKACAVENEELVQ-----HLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEEL 347
LQK + V+ E+ Q H K+ +R+L+ +++E + +C E+ +A+ E
Sbjct: 963 FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQEL--KARYER 1020
Query: 348 KNLRNKTMPNTTSRRYHSLGLFPMDSL--AAEIEGTMRKELQLEEAESPDITHQKRVFET 405
KT + L D L A E + +EL+ ++ + +
Sbjct: 1021 ATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDA 1080
Query: 406 VRNINQVVKQRSLTPSPMNIPGSNQSSAMNSL 437
++ + Q+ K+++ T + + + N L
Sbjct: 1081 MQIMEQMTKEKTETLASLEDTKQTNAKLQNEL 1112
Score = 50.1 bits (118), Expect = 1e-05
Identities = 61/283 (21%), Positives = 125/283 (44%), Gaps = 33/283 (11%)
Query: 120 EEKERDLELAARIGQSLLK---KNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQ 176
E K + E+ + ++LL K K E N L +++E +R++ + + + +D +
Sbjct: 1024 ETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQI 1083
Query: 177 FYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKT 236
E++E + + N LQ +L L+E N+ E ++ K
Sbjct: 1084 MEQMTKEKTETLASLEDTKQTNAK------------LQNELDTLKENNLKNVEELNKSK- 1130
Query: 237 ETITYEEKEQQLVNDCVKELRDA----NVQIASISEELAKKTEDAARQQEEITHLLSQIV 292
E +T E ++ + ++ L+ A + Q++++ EE K E+ R ++E+T
Sbjct: 1131 ELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVT------- 1183
Query: 293 DLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRN 352
QK + +V N +L++ + E L+ + +L E EL+ LRN
Sbjct: 1184 SHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRN 1243
Query: 353 KTM----PNTTSRRYHSLGLFPMDSLAAEIEGTMRK-ELQLEE 390
+ N +++ HS+ + ++S ++E ++ ELQL+E
Sbjct: 1244 EVTVLRGENASAKSLHSV-VQTLESDKVKLELKVKNLELQLKE 1285
Score = 43.9 bits (102), Expect = 7e-04
Identities = 76/389 (19%), Positives = 162/389 (41%), Gaps = 73/389 (18%)
Query: 77 PDANIDLTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSL 136
P ++D++ ++E + + ++T+T + + +T L E E + ++L
Sbjct: 527 PAGDVDMSLSLLQE-----ISSLQEKLEVTRTDHQRE-ITSLKEHFGAREETHQKEIKAL 580
Query: 137 LKKNKTLTERNELLEEQVEHIREEVSQL-------------RHELSMKDELLQFYTSAAE 183
+ L++ NE L+ ++EH +E S + H+ +M++ + F
Sbjct: 581 YTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLGT 640
Query: 184 ESEPESVCSTP--------------LKRNESSSSVQNYFHLDSLQKKL-KDLEEENVVLR 228
E+ + T L+ + S + +++L+ KL K ++E+ L
Sbjct: 641 ETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLE 700
Query: 229 SEASQLKTETITYEEKEQQLV--NDCVKELRDANVQIASISEELAKKTEDAARQQEEITH 286
+ S+L + ++Q LV D + +L++A +++ + E L K + + + T
Sbjct: 701 AIRSKLD------KAEDQHLVEMEDTLNKLQEAEIKVKEL-EVLQAKCNEQTKVIDNFTS 753
Query: 287 LL----SQIVDLQKKAKACA---VENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEM 339
L +++DL KA + E ++L Q L AA+ + L E K +
Sbjct: 754 QLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRE 813
Query: 340 LHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQL-----EEAESP 394
L + +L NL+ S ++++ T+ KELQ+ EA
Sbjct: 814 LQGRELKLTNLQENL------------------SEVSQVKETLEKELQILKEKFAEASEE 855
Query: 395 DITHQKRVFETVRNINQVVKQRSLTPSPM 423
++ Q+ + ETV ++Q +Q ++ S +
Sbjct: 856 AVSVQRSMQETVNKLHQKEEQFNMLSSDL 884
Score = 43.9 bits (102), Expect = 7e-04
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 15/209 (7%)
Query: 100 ERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIRE 159
+ V ++ K+ + + +EE +++E + ++ L E N L E++ R+
Sbjct: 1121 KNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRD 1180
Query: 160 EVS---QLRHELS-MKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQK 215
EV+ +L E S + ++LL+ ++ + L+++ S +S L
Sbjct: 1181 EVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSAL----LTEKDA 1236
Query: 216 KLKDLEEENVVLRSEASQLKT-----ETITYEEKEQQL-VNDCVKELRDANVQIASISEE 269
+L+ L E VLR E + K+ +T+ ++ + +L V + +L++ Q++S S
Sbjct: 1237 ELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGN 1296
Query: 270 L-AKKTEDAARQQEEITHLLSQIVDLQKK 297
+ ED Q+ +I L S IVDLQ+K
Sbjct: 1297 TDTQADEDERAQESQIDFLNSVIVDLQRK 1325
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,174,443
Number of Sequences: 37866
Number of extensions: 1911274
Number of successful extensions: 14163
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 179
Number of HSP's successfully gapped in prelim test: 829
Number of HSP's that attempted gapping in prelim test: 9209
Number of HSP's gapped (non-prelim): 3566
length of query: 953
length of database: 18,247,518
effective HSP length: 112
effective length of query: 841
effective length of database: 14,006,526
effective search space: 11779488366
effective search space used: 11779488366
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.