Guide to the Human Genome
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Search of human proteins with 110815844

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110815844 zinc finger, CCHC domain containing 7 [Homo
sapiens]
         (543 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110815844 zinc finger, CCHC domain containing 7 [Homo sapiens]    1145   0.0  
gi|187608738 zinc finger protein 9 isoform 4 [Homo sapiens]            69   8e-12
gi|187608726 zinc finger protein 9 isoform 1 [Homo sapiens]            68   2e-11
gi|187608744 zinc finger protein 9 isoform 5 [Homo sapiens]            64   5e-10
gi|187608750 zinc finger protein 9 isoform 6 [Homo sapiens]            63   6e-10
gi|187608732 zinc finger protein 9 isoform 2 [Homo sapiens]            62   1e-09
gi|4827071 zinc finger protein 9 isoform 3 [Homo sapiens]              62   1e-09
gi|42558260 zinc finger, CCHC domain containing 13 [Homo sapiens]      53   8e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            46   8e-05
gi|168229156 NFKB activating protein [Homo sapiens]                    43   8e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            42   0.002
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            41   0.002
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    40   0.004
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    40   0.004
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    40   0.007
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       39   0.009
gi|13375938 lin-28 homolog [Homo sapiens]                              39   0.009
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    39   0.012
gi|19923844 coiled-coil domain containing 82 [Homo sapiens]            39   0.012
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    39   0.012
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]            39   0.016
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                38   0.021
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    38   0.027
gi|27883882 P18SRP protein [Homo sapiens]                              38   0.027
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    37   0.035
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     37   0.035
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          37   0.035
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso...    37   0.035
gi|118421089 chromodomain helicase DNA binding protein 2 isoform...    37   0.035
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]     37   0.046

>gi|110815844 zinc finger, CCHC domain containing 7 [Homo sapiens]
          Length = 543

 Score = 1145 bits (2962), Expect = 0.0
 Identities = 543/543 (100%), Positives = 543/543 (100%)

Query: 1   MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSG 60
           MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSG
Sbjct: 1   MMFGGYETIEAYEDDLYRDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSG 60

Query: 61  NSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLS 120
           NSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLS
Sbjct: 61  NSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAHGLS 120

Query: 121 SSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG 180
           SSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG
Sbjct: 121 SSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLG 180

Query: 181 CEVDDKDDDILLNLVGCENSVTEGEDGINWSISDKDIEAQIANNRTPGRWTQRYYSANKN 240
           CEVDDKDDDILLNLVGCENSVTEGEDGINWSISDKDIEAQIANNRTPGRWTQRYYSANKN
Sbjct: 181 CEVDDKDDDILLNLVGCENSVTEGEDGINWSISDKDIEAQIANNRTPGRWTQRYYSANKN 240

Query: 241 IICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAPLCEYCPVPKMLDHSCLFRH 300
           IICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAPLCEYCPVPKMLDHSCLFRH
Sbjct: 241 IICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAPLCEYCPVPKMLDHSCLFRH 300

Query: 301 SWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYG 360
           SWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYG
Sbjct: 301 SWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYG 360

Query: 361 HECPEREVYDPSPVSPFICYYDDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAAN 420
           HECPEREVYDPSPVSPFICYYDDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAAN
Sbjct: 361 HECPEREVYDPSPVSPFICYYDDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAAN 420

Query: 421 ENPHHDIRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTY 480
           ENPHHDIRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTY
Sbjct: 421 ENPHHDIRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTY 480

Query: 481 SSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRK 540
           SSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRK
Sbjct: 481 SSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRK 540

Query: 541 KKS 543
           KKS
Sbjct: 541 KKS 543


>gi|187608738 zinc finger protein 9 isoform 4 [Homo sapiens]
          Length = 172

 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 42/145 (28%), Positives = 61/145 (42%), Gaps = 14/145 (9%)

Query: 225 RTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAP--- 281
           R+ GR  Q + S++   IC  C + GHL+K+C L   V  C+ C R GH+   C  P   
Sbjct: 30  RSRGRGFQ-FVSSSLPDICYRCGESGHLAKDCDLQEDVEACYNCGRGGHIAKDCKEPKRE 88

Query: 282 ---LCEYCPVPKMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKP 338
               C  C  P  L   C   H+ +++C  C   GH    CT++        + G     
Sbjct: 89  REQCCYNCGKPGHLARDC--DHADEQKCYSCGEFGHIQKDCTKV-----KCYRCGETGHV 141

Query: 339 KTPSRPSALAYCYHCAQKGHYGHEC 363
                 ++   CY C + GH   EC
Sbjct: 142 AINCSKTSEVNCYRCGESGHLAREC 166



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 26/108 (24%), Positives = 34/108 (31%), Gaps = 16/108 (14%)

Query: 265 CFLCSRRGHLLYSCPAPLCEYCPVPKMLDHSCLFRHSWDKQCDRCHMLGHY--------- 315
           CF C R GH    CP        +            S    C RC   GH          
Sbjct: 6   CFKCGRSGHWARECPTGGGRGRGMRSRGRGFQFVSSSLPDICYRCGESGHLAKDCDLQED 65

Query: 316 TDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHEC 363
            +AC    R  H+      PK+ +          CY+C + GH   +C
Sbjct: 66  VEACYNCGRGGHIAKDCKEPKREREQC-------CYNCGKPGHLARDC 106


>gi|187608726 zinc finger protein 9 isoform 1 [Homo sapiens]
          Length = 179

 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 38/137 (27%), Positives = 57/137 (41%), Gaps = 13/137 (9%)

Query: 233 RYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAP------LCEYC 286
           ++ S++   IC  C + GHL+K+C L   V  C+ C R GH+   C  P       C  C
Sbjct: 44  QFVSSSLPDICYRCGESGHLAKDCDLQEDVEACYNCGRGGHIAKDCKEPKREREQCCYNC 103

Query: 287 PVPKMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSA 346
             P  L   C   H+ +++C  C   GH    CT++        + G           ++
Sbjct: 104 GKPGHLARDC--DHADEQKCYSCGEFGHIQKDCTKV-----KCYRCGETGHVAINCSKTS 156

Query: 347 LAYCYHCAQKGHYGHEC 363
              CY C + GH   EC
Sbjct: 157 EVNCYRCGESGHLAREC 173


>gi|187608744 zinc finger protein 9 isoform 5 [Homo sapiens]
          Length = 171

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 41/145 (28%), Positives = 62/145 (42%), Gaps = 15/145 (10%)

Query: 225 RTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAP--- 281
           R+ GR  Q + S++   IC  C + GHL+K+C L ++   C+ C R GH+   C  P   
Sbjct: 30  RSRGRGFQ-FVSSSLPDICYRCGESGHLAKDCDL-QEDEACYNCGRGGHIAKDCKEPKRE 87

Query: 282 ---LCEYCPVPKMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKP 338
               C  C  P  L   C   H+ +++C  C   GH    CT++        + G     
Sbjct: 88  REQCCYNCGKPGHLARDC--DHADEQKCYSCGEFGHIQKDCTKV-----KCYRCGETGHV 140

Query: 339 KTPSRPSALAYCYHCAQKGHYGHEC 363
                 ++   CY C + GH   EC
Sbjct: 141 AINCSKTSEVNCYRCGESGHLAREC 165



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 26/107 (24%), Positives = 34/107 (31%), Gaps = 15/107 (14%)

Query: 265 CFLCSRRGHLLYSCPAPLCEYCPVPKMLDHSCLFRHSWDKQCDRCHMLGHYT-------- 316
           CF C R GH    CP        +            S    C RC   GH          
Sbjct: 6   CFKCGRSGHWARECPTGGGRGRGMRSRGRGFQFVSSSLPDICYRCGESGHLAKDCDLQED 65

Query: 317 DACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHEC 363
           +AC    R  H+      PK+ +          CY+C + GH   +C
Sbjct: 66  EACYNCGRGGHIAKDCKEPKREREQC-------CYNCGKPGHLARDC 105


>gi|187608750 zinc finger protein 9 isoform 6 [Homo sapiens]
          Length = 170

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 41/145 (28%), Positives = 60/145 (41%), Gaps = 16/145 (11%)

Query: 225 RTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAP--- 281
           R+ GR  Q + S++   IC  C + GHL+K+C L      C+ C R GH+   C  P   
Sbjct: 30  RSRGRGFQ-FVSSSLPDICYRCGESGHLAKDCDLQEDA--CYNCGRGGHIAKDCKEPKRE 86

Query: 282 ---LCEYCPVPKMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKP 338
               C  C  P  L   C   H+ +++C  C   GH    CT++        + G     
Sbjct: 87  REQCCYNCGKPGHLARDC--DHADEQKCYSCGEFGHIQKDCTKV-----KCYRCGETGHV 139

Query: 339 KTPSRPSALAYCYHCAQKGHYGHEC 363
                 ++   CY C + GH   EC
Sbjct: 140 AINCSKTSEVNCYRCGESGHLAREC 164



 Score = 36.2 bits (82), Expect = 0.079
 Identities = 27/106 (25%), Positives = 34/106 (32%), Gaps = 14/106 (13%)

Query: 265 CFLCSRRGHLLYSCPAPLCEYCPVPKMLDHSCLFRHSWDKQCDRCHMLGHYT-------D 317
           CF C R GH    CP        +            S    C RC   GH         D
Sbjct: 6   CFKCGRSGHWARECPTGGGRGRGMRSRGRGFQFVSSSLPDICYRCGESGHLAKDCDLQED 65

Query: 318 ACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQKGHYGHEC 363
           AC    R  H+      PK+ +          CY+C + GH   +C
Sbjct: 66  ACYNCGRGGHIAKDCKEPKREREQC-------CYNCGKPGHLARDC 104


>gi|187608732 zinc finger protein 9 isoform 2 [Homo sapiens]
          Length = 178

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 37/137 (27%), Positives = 58/137 (42%), Gaps = 14/137 (10%)

Query: 233 RYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAP------LCEYC 286
           ++ S++   IC  C + GHL+K+C L ++   C+ C R GH+   C  P       C  C
Sbjct: 44  QFVSSSLPDICYRCGESGHLAKDCDL-QEDEACYNCGRGGHIAKDCKEPKREREQCCYNC 102

Query: 287 PVPKMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSA 346
             P  L   C   H+ +++C  C   GH    CT++        + G           ++
Sbjct: 103 GKPGHLARDC--DHADEQKCYSCGEFGHIQKDCTKV-----KCYRCGETGHVAINCSKTS 155

Query: 347 LAYCYHCAQKGHYGHEC 363
              CY C + GH   EC
Sbjct: 156 EVNCYRCGESGHLAREC 172


>gi|4827071 zinc finger protein 9 isoform 3 [Homo sapiens]
          Length = 177

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 37/137 (27%), Positives = 56/137 (40%), Gaps = 15/137 (10%)

Query: 233 RYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAP------LCEYC 286
           ++ S++   IC  C + GHL+K+C L      C+ C R GH+   C  P       C  C
Sbjct: 44  QFVSSSLPDICYRCGESGHLAKDCDLQEDA--CYNCGRGGHIAKDCKEPKREREQCCYNC 101

Query: 287 PVPKMLDHSCLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSA 346
             P  L   C   H+ +++C  C   GH    CT++        + G           ++
Sbjct: 102 GKPGHLARDC--DHADEQKCYSCGEFGHIQKDCTKV-----KCYRCGETGHVAINCSKTS 154

Query: 347 LAYCYHCAQKGHYGHEC 363
              CY C + GH   EC
Sbjct: 155 EVNCYRCGESGHLAREC 171


>gi|42558260 zinc finger, CCHC domain containing 13 [Homo sapiens]
          Length = 166

 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 4/82 (4%)

Query: 242 ICRNCDKRGHLSKNCPLPRKVRR--CFLCSRRGHLLYSCPAPLCEYCPVPKMLDHSCLFR 299
           IC NC + GH++K+C  P++ RR  C+ C R GHL   C     + C     L H  + +
Sbjct: 66  ICYNCGRSGHIAKDCKDPKRERRQHCYTCGRLGHLARDCDRQKEQKCYSCGKLGH--IQK 123

Query: 300 HSWDKQCDRCHMLGHYTDACTE 321
                +C RC  +GH    C++
Sbjct: 124 DCAQVKCYRCGEIGHVAINCSK 145



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 30/134 (22%), Positives = 43/134 (32%), Gaps = 42/134 (31%)

Query: 236 SANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCPAPLCEYCPVPKMLDHS 295
           S   +  C  C + G  +KNC L   +  C+ C R GH+   C  P              
Sbjct: 40  STTLSYTCYCCGESGRNAKNCVLLGNI--CYNCGRSGHIAKDCKDP-------------- 83

Query: 296 CLFRHSWDKQCDRCHMLGHYTDACTEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQ 355
              +    + C  C  LGH    C                K+ K          CY C +
Sbjct: 84  ---KRERRQHCYTCGRLGHLARDCDR-------------QKEQK----------CYSCGK 117

Query: 356 KGHYGHECPEREVY 369
            GH   +C + + Y
Sbjct: 118 LGHIQKDCAQVKCY 131


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 11/163 (6%)

Query: 384 KYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQEN 443
           K E +EREKR +++ K  K+     E       K   +    + +K R   ++    ++ 
Sbjct: 60  KKERREREKRKREREKERKRERGKKEK------KGERKKEERERKKRRREKENKEGEEKE 113

Query: 444 KETQKEMKNKNRNW----EKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSS 499
           K  +KE K + R      E+ RK +R RE  ++  R  +        K +K  +   +  
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERK-KRERKQVG 172

Query: 500 HYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKKK 542
                R++K  KE K+ ++ +KER  E +  +     K+RKKK
Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215



 Score = 37.0 bits (84), Expect = 0.046
 Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 7/160 (4%)

Query: 384 KYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQEN 443
           K E +ER+KR ++K     K G   E  K    K           + R   +  R  ++ 
Sbjct: 91  KKEERERKKRRREKEN---KEGEEKEKRKKKEKKERGRTSKEGKERERKE-ERKREERKE 146

Query: 444 KETQKEMKNKNRNWEKHRKADRHR--EVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSHY 501
           +E +KE + K R  ++ +K +R +  E +E+     +          ++  K   R    
Sbjct: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR 206

Query: 502 HTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKK 541
              +E K  +E K+ +QK ++  W + +       K+RKK
Sbjct: 207 ERKKERKKKEERKKERQKDRQTNWREKERGKRER-KERKK 245



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 29/158 (18%), Positives = 65/158 (41%), Gaps = 6/158 (3%)

Query: 386 EIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQ-ENK 444
           EI+ERE+ ++ +     K G     S+    +   E    +  K R   +  +  + E K
Sbjct: 37  EIREREREIETR-----KEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERK 91

Query: 445 ETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSHYHTS 504
           + ++E K + R  E     ++ +   ++     +T       + ++  K   R       
Sbjct: 92  KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151

Query: 505 REDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKKK 542
            E +  +E K  K++++++  E ++       K+RKK+
Sbjct: 152 EEREKERERKERKKRERKQVGEKEEERKEKERKERKKR 189


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 55/251 (21%), Positives = 89/251 (35%), Gaps = 38/251 (15%)

Query: 300 HSWDKQCDR---CHMLGHYTDAC-TEIWRQYHLTTKPGPPKKPKTPSRPSALAYCYHCAQ 355
           HS  +  DR    H LG  +     + +R    +     P  P+     SA +  Y+ + 
Sbjct: 45  HSCSRSGDRNGLTHQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSY 104

Query: 356 KGHYGHECPEREVYDPSPVSPFICYYDDKYEIQEREKRLKQKIKVLK-----------KN 404
              YG +             P+    D + E   R+KRL ++ ++ +           KN
Sbjct: 105 SRPYGSD------------KPWPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKN 152

Query: 405 GVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQE-NKETQKEMKNKNRNWEKHRKA 463
              PEP    +    +E P         S +  +     +KE  K+ + K  +  KH+K 
Sbjct: 153 ---PEPDSDEHTPVEDEEPKKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKY 209

Query: 464 DRHREVDEDFPRGPKTYSSPGSFK--TQKPSKPFHRSSHYHTSREDKSPKE-----GKRG 516
               + D D         +    K   +K  K  HRS  Y   R  KS KE      K  
Sbjct: 210 SEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKESSDSSSKES 269

Query: 517 KQKKKERCWED 527
           +++  E  W+D
Sbjct: 270 QEEFLENPWKD 280


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 41/166 (24%), Positives = 69/166 (41%), Gaps = 11/166 (6%)

Query: 384 KYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQEN 443
           K E +EREKR +++ K  K+     E  K    +   E      RK R   +  R  +E 
Sbjct: 37  KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERK--RKEREKQRKERREKER 94

Query: 444 KETQKEMKNKNRNW-------EKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFH 496
           ++ +KE K + R         +K  + +R RE  +   R  K        K +K  K   
Sbjct: 95  RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREK--E 152

Query: 497 RSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKKK 542
           R       ++ K  +  K+ ++ +KER  E +  +     K+RKK+
Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKE 198


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 25/107 (23%), Positives = 52/107 (48%), Gaps = 1/107 (0%)

Query: 437 NRWPQENKETQKEM-KNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPF 495
           +R  Q  +ET++E  + + R  ++ RK    RE D+D  R  K  +     + +K  +  
Sbjct: 63  DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRER 122

Query: 496 HRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKKK 542
            + +     RE +  ++ +R +Q+++ER  E D     +  ++ +KK
Sbjct: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 25/104 (24%), Positives = 51/104 (49%), Gaps = 14/104 (13%)

Query: 441 QENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSH 500
           +  ++ Q+E +N+     +HR+ DRHRE D    R  +        + ++  +   R   
Sbjct: 18  ERERDRQRERENQTERENRHRQRDRHRERDRQTDREKE--------RERQKERDRQRQRE 69

Query: 501 YHTSREDKSPKEGKRGKQKKKERCWE-DDDNDNLFLIKQRKKKS 543
             T RE +  +E +R +++K++   E D D D     ++RK+++
Sbjct: 70  RETERETERQRERQRQRERKRQTDRERDKDRD-----RERKRET 108



 Score = 29.3 bits (64), Expect = 9.6
 Identities = 24/105 (22%), Positives = 49/105 (46%), Gaps = 9/105 (8%)

Query: 441 QENKETQKEMKNK-NRNWEKHRKADRHR----EVDEDFPRGPKTYSSPGSFKTQKPSKPF 495
           + +K+  +E K + +RN E++RK  R R    E + D  R  +        + ++  +  
Sbjct: 95  ERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRET 154

Query: 496 HRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRK 540
            R       RE++  +  K  K+++KE+  E+   ++    K+RK
Sbjct: 155 DRERQRWAEREERKKERKKERKKERKEKKKEEKRRED----KKRK 195


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/111 (26%), Positives = 56/111 (50%), Gaps = 11/111 (9%)

Query: 435 KSNRWPQENKETQKEMKNK--NRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPS 492
           + NR  +  +E Q+E +NK  +R+ E+ R+ +R RE + +  R  +T       + +   
Sbjct: 182 EKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT------DRERDRQ 235

Query: 493 KPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKKKS 543
           +   R       RE  S +E +R K++++ER   D D D     K+R++++
Sbjct: 236 RKTEREREKQAERERASERETERDKERERER---DRDRDRDRRQKERERQT 283



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 441 QENKETQKEMKNKN---RNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHR 497
           +E ++T++E   K    R  ++HRK DRHRE   D  +  +  +     + ++  +   +
Sbjct: 66  REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK 125

Query: 498 SSHYHTSREDKSPKEGKRGKQKKKER 523
                T RE +  ++ +   Q+++ER
Sbjct: 126 ERERETEREGERGRDRQTDGQRERER 151



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 21/101 (20%), Positives = 50/101 (49%), Gaps = 1/101 (0%)

Query: 428 RKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFK 487
           R+ +   K  R  + ++ET+++ + + R  E+ R+ +R RE + +  R  +        +
Sbjct: 279 RERQTDRKRQRRTERDRETERK-RERQRERERERERNRKRERERERERERERQRETERDR 337

Query: 488 TQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDD 528
            ++  +   R +     R  ++ +EG+R  ++++ER  E D
Sbjct: 338 EKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERD 378



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 26/109 (23%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 437 NRWPQENKETQKEMKNKN---RNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSK 493
           NR  +  +E ++E + +    R+ EK R+  R R+ + D  R  +T         ++  +
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER 373

Query: 494 PFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKKK 542
              R       RE++  ++  R +QK++ER  E D +      KQR+++
Sbjct: 374 ERERDRQSAREREERE-RDRDRDRQKERERQTEKDRDGQRETEKQRERE 421



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 26/138 (18%), Positives = 62/138 (44%), Gaps = 24/138 (17%)

Query: 388 QEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGR--ASWKSNRWPQENKE 445
           +ERE+  +++ +  +      E  +    +   E      R+GR  A  +  R  + +++
Sbjct: 321 RERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQ 380

Query: 446 TQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSHYHTSR 505
           + +E + + R+ ++ R+ +R R+ ++D           G  +T+K              R
Sbjct: 381 SAREREERERDRDRDRQKERERQTEKD---------RDGQRETEK-------------QR 418

Query: 506 EDKSPKEGKRGKQKKKER 523
           E +  +E +RG+++ +ER
Sbjct: 419 EREKDRESERGRERGRER 436



 Score = 29.3 bits (64), Expect = 9.6
 Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 8/83 (9%)

Query: 441 QENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSH 500
           + N++ ++E + + R  E  R+ DR RE   +  R  K        + ++  +   +   
Sbjct: 55  ERNRQKERERRREKRQTE--RETDRKRERRREKDRHRK------RDRHRERQRDREKERE 106

Query: 501 YHTSREDKSPKEGKRGKQKKKER 523
             T RE    +E +R +QK++ER
Sbjct: 107 RQTDRERDRQREKERNRQKERER 129


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 26/119 (21%), Positives = 54/119 (45%), Gaps = 4/119 (3%)

Query: 428 RKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFK 487
           +K + + ++    +  +E +KE K K +  EK ++ ++ ++  E   R  K        +
Sbjct: 5   KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64

Query: 488 TQKPSKPFHR----SSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNLFLIKQRKKK 542
            +K  K               +E++  +EG+R K+KKK R  E+++       ++ KKK
Sbjct: 65  KRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 106/502 (21%), Positives = 194/502 (38%), Gaps = 64/502 (12%)

Query: 58  NSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRVQAQENAH 117
           +S  SE +SS P   +L +  +++ I  S        S+ D +   K +      +  + 
Sbjct: 25  SSEESEETSSPP---RLAMNQNTDKISGSG-------SNSDMMENSKEEGTSSSEKSKSS 74

Query: 118 GLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWM 177
           G S S +   +V K  +SD EKP  +E         + E +S+E  E+ I+     +  +
Sbjct: 75  GSSRSKRKPSIVTKYVESDDEKPLDDE--------TVNEDASNENSENDITMQSLPKGTV 126

Query: 178 LLGCEV---DDKDD-----DILLNLVGCENSVTEGEDGINWSISDKDIEAQIANNRTPGR 229
           ++  E    +DKDD         + +  EN    GEDG++  +S      Q+ + +    
Sbjct: 127 IVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSI 186

Query: 230 WTQRYYSANKNIICRNCDK---RGHLSKNCPLPRKVRRCFLCSRRGHLLYS--CPAPLCE 284
           +    + + + +IC+NC K      +S++        +C  C+  G+L+    C    C+
Sbjct: 187 YR---HPSLQVLICKNCFKYYMSDDISRDS--DGMDEQCRWCAEGGNLICCDFCHNAFCK 241

Query: 285 YCPVPKM--LDHSCLFRHSWDKQCDRCH--MLGHYTDACTEIWRQYHLTTKPGPPKKPKT 340
            C +  +   + S +   +    C  CH   L     AC  ++       +    KK K 
Sbjct: 242 KCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQN-KKKIKV 300

Query: 341 PSRPSALAYCY--HCAQKGHYGHECPEREVYDPSPVSPFICYYDDKYEIQEREKRLKQKI 398
            S  S   Y +    + K    +   E +  D S        Y      +E  K+ K+ I
Sbjct: 301 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI 360

Query: 399 -----------KVLKK---NGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQENK 444
                      K LK+   N  I   +KL  +KA  ++   DI+K   + + +     ++
Sbjct: 361 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAF-KSVLADIKKAHLALEED---LNSE 416

Query: 445 ETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQ-KPSKPFHRSSHYHT 503
               +  NK +N ++H+  D   E        P         K++ K S+    S H H 
Sbjct: 417 FRAMDAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQ 476

Query: 504 S--REDKSPKEGKRGKQKKKER 523
           +   E++   +   G+ KK +R
Sbjct: 477 NVPTEEQRTNKSTGGEHKKSDR 498



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 35/153 (22%), Positives = 62/153 (40%), Gaps = 17/153 (11%)

Query: 386  EIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQENKE 445
            E +E+ K LK K     ++G+     K      ++E    D ++ +   +  + P + K+
Sbjct: 941  ETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKK 1000

Query: 446  TQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTY---SSPGSFKTQK----PSKPFHRS 498
               +M+ +  +     +    RE    FP+G K     ++ G  K++K     SK     
Sbjct: 1001 KVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDEL 1060

Query: 499  SHYHT----------SREDKSPKEGKRGKQKKK 521
            S Y            S EDK  K G  G++KK+
Sbjct: 1061 SDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKR 1093



 Score = 29.3 bits (64), Expect = 9.6
 Identities = 29/129 (22%), Positives = 59/129 (45%), Gaps = 9/129 (6%)

Query: 417  KAANENPHHDIRKGRASWKSNRWPQENKETQK----EMKNKNRNWEKHRKADRHREVDED 472
            K      H ++ KGR   K +    E+ + Q+    E  +++ + ++ R     +   E+
Sbjct: 1356 KKTKPKEHKEV-KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE 1414

Query: 473  FPRGPKTYSSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDN 532
              R  K        K Q+ S   ++S+    S E++  KE +  +++++E   ED+++D+
Sbjct: 1415 NQRSYKQKKKRRRIKVQEDSSSENKSN----SEEEEEEKEEEEEEEEEEEEEEEDENDDS 1470

Query: 533  LFLIKQRKK 541
                K RKK
Sbjct: 1471 KSPGKGRKK 1479


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 30/140 (21%), Positives = 65/140 (46%), Gaps = 7/140 (5%)

Query: 384  KYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQEN 443
            +Y  Q  E R +++  V  K   + EP        A+E+   +  +GR   +   W +  
Sbjct: 2077 EYRNQTFEGRQRERFDVGPKEKPLEEPDAQG---RASEDRRRERERGRNWSRERDWDRPR 2133

Query: 444  KETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSHYHT 503
            +  +   K+ +R+W+++R+   +R+ + +  RG +   S    + ++  +   R      
Sbjct: 2134 EWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSR 2193

Query: 504  SRE---DKSPKEGKRGKQKK 520
            SRE   DK+ ++ +RG+ +K
Sbjct: 2194 SRERDRDKA-RDRERGRDRK 2212


>gi|13375938 lin-28 homolog [Homo sapiens]
          Length = 209

 Score = 39.3 bits (90), Expect = 0.009
 Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 2/58 (3%)

Query: 222 ANNRTPGRWTQRYYSANKNIICRNCDKRGHLSKNCPLPRKVRRCFLCSRRGHLLYSCP 279
           +  R  G+  Q+  S  K   C NC    H +K C LP + ++C  C    H++ SCP
Sbjct: 120 SERRPKGKSMQKRRS--KGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCP 175


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 8/127 (6%)

Query: 420 NENPHHDIRKGRASWKS---NRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRG 476
           +++PH    K R   KS   +    + K+T++++K K R  EK R+ +R RE +    R 
Sbjct: 351 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE----RE 406

Query: 477 PKTYSSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDD-DNDNLFL 535
            +        + ++  K   +       RE +   E  R K+K+KE+  E + + D    
Sbjct: 407 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 466

Query: 536 IKQRKKK 542
           I +++KK
Sbjct: 467 IDEKRKK 473


>gi|19923844 coiled-coil domain containing 82 [Homo sapiens]
          Length = 544

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 51/212 (24%), Positives = 89/212 (41%), Gaps = 16/212 (7%)

Query: 18  RDESSSELSVDSEVEFQLYSQIHYAQDLDDVIREEEHEEKNSGNSESSSSKPNQKKLIVL 77
           R   S  L  D E++ + +      ++LD     E  EE +S      +  P  ++ + L
Sbjct: 31  RSSISQLLDSDEELDSEEFDS---DEELDSDESFENDEELDSNKGPDCNKTPGSERELNL 87

Query: 78  SDSEVIQLSDGSEVITLSDEDSIY-----RCKGKNVRVQAQENAHGLSSSLQSNELVDKK 132
           S  ++    + S+ +  S   S Y     + K +N+ +Q QE  H        N+   + 
Sbjct: 88  S--KIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEK-HLSQEDNDLNKQTGQI 144

Query: 133 CKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEGDNVESWMLLGCEVDDKDD-DIL 191
            + D EK  S+E + + ++   I     EEE+    +   + S M   C+ D+ DD DIL
Sbjct: 145 IEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVM---CDSDESDDSDIL 201

Query: 192 LNLVGCENSVTEGED-GINWSISDKDIEAQIA 222
           +  VG +      ED G +  +  K  E  +A
Sbjct: 202 VRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLA 233


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 38.9 bits (89), Expect = 0.012
 Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 8/127 (6%)

Query: 420 NENPHHDIRKGRASWKS---NRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRG 476
           +++PH    K R   KS   +    + K+T++++K K R  EK R+ +R RE +    R 
Sbjct: 235 SKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE----RE 290

Query: 477 PKTYSSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDD-DNDNLFL 535
            +        + ++  K   +       RE +   E  R K+K+KE+  E + + D    
Sbjct: 291 KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 350

Query: 536 IKQRKKK 542
           I +++KK
Sbjct: 351 IDEKRKK 357


>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 38.5 bits (88), Expect = 0.016
 Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 4/99 (4%)

Query: 425 HDIRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPG 484
           H I +  ++WK  R     K+T K+ K K    +K +K    ++      +   T     
Sbjct: 14  HVITEKESAWKRGR----KKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTT 69

Query: 485 SFKTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKER 523
           +  T++  K   +       +E +  KE K+ K+KKK++
Sbjct: 70  TTTTKEKEKEKEKEKEKEKEKEKEKEKEKKKKKKKKKKK 108


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 38.1 bits (87), Expect = 0.021
 Identities = 31/146 (21%), Positives = 63/146 (43%), Gaps = 10/146 (6%)

Query: 397 KIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQENKETQKEMKNKNRN 456
           K  VL +N    +PS+        E+P  +  K   +          K+ QK ++  +R 
Sbjct: 182 KRNVLGRNLTANDPSQEYVASEGEEDPEVEFLKSLTT----------KQKQKLLRKLDRL 231

Query: 457 WEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRG 516
            +K +K DR ++  +      K + S  S  +   S     +S   +  E  + ++  + 
Sbjct: 232 EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQR 291

Query: 517 KQKKKERCWEDDDNDNLFLIKQRKKK 542
           K++KK +C   +++D+    K +K+K
Sbjct: 292 KKRKKNKCSGHNNSDSEEKDKSKKRK 317


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 37.7 bits (86), Expect = 0.027
 Identities = 26/152 (17%), Positives = 67/152 (44%), Gaps = 11/152 (7%)

Query: 382 DDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNR--W 439
           + + E++E+EK L+++ K+ ++   + E  +  +     E       +    W+     W
Sbjct: 287 EQEKELREQEKELREQKKLREQEEQMQEQEEKMW-----EQEEKMREQEEKMWRQEERLW 341

Query: 440 PQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSS 499
            QE +  ++E K +++      + +R RE +E      K +      + ++  +   +  
Sbjct: 342 EQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKM 401

Query: 500 HYHTSREDKSPKEGKRGKQKKKERCWEDDDND 531
                 E+++ +E +   QK++E  WE ++ +
Sbjct: 402 R----EEEETMREQEEKMQKQEENMWEQEEKE 429



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 23/107 (21%), Positives = 49/107 (45%), Gaps = 2/107 (1%)

Query: 427 IRKGRASWKSNRWPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSF 486
           +R+ +  W+     +E K+TQ++ K      EK R+ +R RE ++   R  +        
Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKM-REEEEMMREQEE 581

Query: 487 KTQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKERCWEDDDNDNL 533
           K Q+  +           +E+K  +E +    +++E+ WE ++ D +
Sbjct: 582 KMQEQEEKMREQEEKMWEQEEKM-QEQEEKMWEQEEKMWEQEEEDKM 627


>gi|27883882 P18SRP protein [Homo sapiens]
          Length = 155

 Score = 37.7 bits (86), Expect = 0.027
 Identities = 29/105 (27%), Positives = 54/105 (51%), Gaps = 4/105 (3%)

Query: 422 NPHHDIRKGRASWKSNRWPQENKETQK--EMKNKNRNWEKHRKADRHREVDEDFPRGPKT 479
           +P  DI    +S  S    +EN+E  K   ++ K  N E+ +K ++ +E  +   +  ++
Sbjct: 35  DPKRDIVLDVSSTSSEDSDEENEELNKLQALQEKRINEEEEKKKEKSKEKIKLKKKRKRS 94

Query: 480 YSSPGSFK-TQKPSKPFHRSSHYHTSREDKSPKEGKRGKQKKKER 523
           YSS  + + T K  K  ++       ++ KS K+GK  K++KK+R
Sbjct: 95  YSSSSTEEDTSKQKKQKYQKKEKKKEKKSKS-KKGKHHKKEKKKR 138



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 16/141 (11%)

Query: 342 SRPSALAYCYHCAQKGHYGHEC-------PERE-VYDPSPVSPFICYYDDKYEIQEREKR 393
           ++ S  A C  C   GH   EC       P+R+ V D S  S      +D  E  E   +
Sbjct: 7   NKDSVRAGCKKCGYPGHLTFECRNFLRVDPKRDIVLDVSSTSS-----EDSDEENEELNK 61

Query: 394 LK--QKIKVLKKNGVIPEPSKLPY-IKAANENPHHDIRKGRASWKSNRWPQENKETQKEM 450
           L+  Q+ ++ ++     E SK    +K   +  +        + K  +   + KE +KE 
Sbjct: 62  LQALQEKRINEEEEKKKEKSKEKIKLKKKRKRSYSSSSTEEDTSKQKKQKYQKKEKKKEK 121

Query: 451 KNKNRNWEKHRKADRHREVDE 471
           K+K++  + H+K  + R+ ++
Sbjct: 122 KSKSKKGKHHKKEKKKRKKEK 142


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 37.4 bits (85), Expect = 0.035
 Identities = 40/157 (25%), Positives = 55/157 (35%), Gaps = 33/157 (21%)

Query: 259  PRKVRRCFLCSRRGHLLY----SCPAPLCEYC------PVPKMLDHSCLFRHSWDKQCDR 308
            PR V  CFLC+  GH+ +     C  P  ++C      P+   L++ C  R  +   C R
Sbjct: 1430 PRVV--CFLCASSGHVEFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGR 1487

Query: 309  CHMLGHYTDACTEIWRQYH-LTTKPGPPKKPKTPSRPSALAYCYHC-------------A 354
             H        C +    YH     P  P KP    +      C  C             A
Sbjct: 1488 QHQATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDA 1547

Query: 355  QKGH---YGHECPEREVYDPSPVSPFI--CYYDDKYE 386
            Q  H     H+C   +++      P    CY DD YE
Sbjct: 1548 QWSHDFSLCHDC--AKLFAKGNFCPLCDKCYDDDDYE 1582


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 37.4 bits (85), Expect = 0.035
 Identities = 49/211 (23%), Positives = 77/211 (36%), Gaps = 43/211 (20%)

Query: 335 PKKPKTPSRPSALAYCYHCAQKGHYGHECPEREVYDPSPVSPFICYYDDKYEIQEREKRL 394
           P+K K+P +  A A               PE+E+     V         K  ++E EK  
Sbjct: 796 PEKAKSPLKEDAKA---------------PEKEIPKKEEV---------KSPVKEEEKPQ 831

Query: 395 KQKIKVLKKNGVIPEPSKLPYIKAANEN--------PHHDIRKGRASWKSNRWPQENKET 446
           + K+K   K     E  K P      E         P  +  K +   K     ++ KE+
Sbjct: 832 EVKVKEPPKKA---EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES 888

Query: 447 QKEMKNKNRNWEK-----HRKADRHREVDEDFPRGPKTY---SSPGSFKTQKPSKPFHRS 498
           + E K +    +K      ++A    EV ED     KT      P   K ++PSKP  + 
Sbjct: 889 KVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK 948

Query: 499 SHYHTSREDKSPKEGKRGKQKKKERCWEDDD 529
                 ++ K  K  K  ++ K E   ++DD
Sbjct: 949 EAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 37.4 bits (85), Expect = 0.035
 Identities = 37/145 (25%), Positives = 56/145 (38%), Gaps = 24/145 (16%)

Query: 382 DDKYEIQEREKRLKQKIKVLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASWKSNRWPQ 441
           +DK  I++ EK  K+++K   K  +  E  K P  +   E P  +++K     +     +
Sbjct: 664 EDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKK 723

Query: 442 ENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQ----KPSKPFHR 497
           E KE +KE+K                      P+  K  S+P S   +    KP  P   
Sbjct: 724 EEKEPKKEIKK--------------------LPKDAKKSSTPLSEAKKPAALKPKVPKKE 763

Query: 498 SSHYHTSREDKSPKEGKRGKQKKKE 522
            S    S     PKE  + K  KKE
Sbjct: 764 ESVKKDSVAAGKPKEKGKIKVIKKE 788


>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
           isoform 1 [Homo sapiens]
          Length = 483

 Score = 37.4 bits (85), Expect = 0.035
 Identities = 42/154 (27%), Positives = 70/154 (45%), Gaps = 23/154 (14%)

Query: 382 DDKYEIQEREKRLKQKIKVLKKNGVIPEPSKL---PYIKAANENPHHDIRKGRASWKSNR 438
           +++ + +E EKR ++ I+ LKK   IPE  KL   P IK      H  +   +A  + N 
Sbjct: 231 EERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKV-----HRFLL--QAVNQKNL 283

Query: 439 WPQENKETQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTY--SSPGSFKTQKPSKPFH 496
             +  K  +KE+  +    EK +K D+    DE       T    S    K +KP +P  
Sbjct: 284 LKKPEKGDEKELDKR----EKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPED 339

Query: 497 RSSHYHTSRE-------DKSPKEGKRGKQKKKER 523
            S   +  RE       ++  +E +R K++++ER
Sbjct: 340 ESGRDYREREREYERDQERILRERERLKRQEEER 373


>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
            [Homo sapiens]
          Length = 1828

 Score = 37.4 bits (85), Expect = 0.035
 Identities = 27/111 (24%), Positives = 52/111 (46%), Gaps = 5/111 (4%)

Query: 391  EKRLKQKIKVLKKNGVIPEPSKLPYIKAAN----ENPHHDIR-KGRASWKSNRWPQENKE 445
            E +LK++   +KK   +P   +   I+ ++    +NP  +   K     KS    ++ K+
Sbjct: 1336 EAKLKKRKPRVKKENKVPRLKEEHGIELSSPRHSDNPSEEGEVKDDGLEKSPMKKKQKKK 1395

Query: 446  TQKEMKNKNRNWEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFH 496
              KE K K  +  K ++ D+ R+  +D    PK+  +  S K+++   P H
Sbjct: 1396 ENKENKEKQMSSRKDKEGDKERKKSKDKKEKPKSGDAKSSSKSKRSQGPVH 1446



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 33/133 (24%), Positives = 50/133 (37%), Gaps = 7/133 (5%)

Query: 400 VLKKNGVIPEPSKLPYIKAANENPHHDIRKGRASW---KSNRWPQENKETQKEMKNKNRN 456
           V + N    EPS+    + A+        K R      K  +W QE  E ++E      +
Sbjct: 109 VRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAES 168

Query: 457 WEKHRKADRHREVDEDFPRGPKTYSSPGSFKTQKPSKPFHRSSHYHTSREDKSPKEGKRG 516
             + +K    R V       P+    P   KTQ+  +    SS      +D++PK   R 
Sbjct: 169 EPEQKKVKARRPVPRRTVPKPRVKKQP---KTQRGKRKKQDSSD-EDDDDDEAPKRQTRR 224

Query: 517 KQKKKERCWEDDD 529
           +  K     EDDD
Sbjct: 225 RAAKNVSYKEDDD 237


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score = 37.0 bits (84), Expect = 0.046
 Identities = 44/184 (23%), Positives = 74/184 (40%), Gaps = 28/184 (15%)

Query: 51  EEEHEEKNSGNSESSSSKPNQKKLIVLSDSEVIQLSDGSEVITLSDEDSIYRCKGKNVRV 110
           EEE EE+     E S+S+ ++++     + E    S+  E    S E+           V
Sbjct: 279 EEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE-----------V 327

Query: 111 QAQENAHGLSSSLQSNELVDKKCKSDIEKPKSEERSGVIREVMIIEVSSSEEEESTISEG 170
             +E +       +++ LV  + + D +  +SEE           EV     + S ++EG
Sbjct: 328 SEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEE--------EVGEGTPQSSALTEG 379

Query: 171 DNV-ESWMLLGCEVDDKDDDILLNLVGCE--------NSVTEGEDGINWSISDKDIEAQI 221
           D V +S  LL  E+  +    L  L GC         N + EG  G+ +   DK  +  +
Sbjct: 380 DYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIV 439

Query: 222 ANNR 225
           A  R
Sbjct: 440 ALKR 443


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.131    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,921,532
Number of Sequences: 37866
Number of extensions: 1342558
Number of successful extensions: 5953
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 225
Number of HSP's that attempted gapping in prelim test: 5235
Number of HSP's gapped (non-prelim): 810
length of query: 543
length of database: 18,247,518
effective HSP length: 107
effective length of query: 436
effective length of database: 14,195,856
effective search space: 6189393216
effective search space used: 6189393216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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