Guide to the Human Genome
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Search of human proteins with 169167057

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169167057 PREDICTED: hypothetical protein [Homo sapiens]
         (320 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169167057 PREDICTED: hypothetical protein [Homo sapiens]           667   0.0  
gi|113416171 PREDICTED: hypothetical protein [Homo sapiens]           423   e-118
gi|169166294 PREDICTED: hypothetical protein [Homo sapiens]           418   e-117
gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]            48   1e-05
gi|239748995 PREDICTED: hypothetical protein XP_002346877 [Homo ...    47   3e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    46   4e-05
gi|239755634 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|239744429 PREDICTED: hypothetical protein XP_002343157 [Homo ...    44   2e-04
gi|239751929 PREDICTED: hypothetical protein [Homo sapiens]            44   2e-04
gi|239746415 PREDICTED: hypothetical protein XP_002344217 [Homo ...    44   2e-04
gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo ...    43   3e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    43   3e-04
gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo ...    43   3e-04
gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]            43   3e-04
gi|38569493 potassium voltage-gated channel, subfamily H (eag-re...    43   3e-04
gi|169214061 PREDICTED: hypothetical protein [Homo sapiens]            43   4e-04
gi|169214437 PREDICTED: hypothetical protein [Homo sapiens]            43   4e-04
gi|169213353 PREDICTED: hypothetical protein [Homo sapiens]            43   4e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         42   7e-04
gi|239746609 PREDICTED: hypothetical protein XP_002343799 [Homo ...    42   0.001
gi|13376335 hypothetical protein LOC79946 [Homo sapiens]               41   0.001
gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]             40   0.002
gi|239753883 PREDICTED: hypothetical protein [Homo sapiens]            40   0.003
gi|239748442 PREDICTED: hypothetical protein XP_002346660 [Homo ...    40   0.003
gi|239742378 PREDICTED: hypothetical protein XP_002342507 [Homo ...    40   0.003
gi|239741753 PREDICTED: hypothetical protein [Homo sapiens]            40   0.003
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    40   0.003
gi|21361699 sphingosine kinase 2 [Homo sapiens]                        40   0.004
gi|239741603 PREDICTED: hypothetical protein XP_002342247 [Homo ...    39   0.005
gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]            39   0.006

>gi|169167057 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 320

 Score =  667 bits (1720), Expect = 0.0
 Identities = 320/320 (100%), Positives = 320/320 (100%)

Query: 1   MSPLETNKGSIGQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVSTATVT 60
           MSPLETNKGSIGQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVSTATVT
Sbjct: 1   MSPLETNKGSIGQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVSTATVT 60

Query: 61  SSGASAPGSADPTLGSTAARRASAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSP 120
           SSGASAPGSADPTLGSTAARRASAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSP
Sbjct: 61  SSGASAPGSADPTLGSTAARRASAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSP 120

Query: 121 CPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWEKRQDKRLETHPCRAPPL 180
           CPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWEKRQDKRLETHPCRAPPL
Sbjct: 121 CPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWEKRQDKRLETHPCRAPPL 180

Query: 181 PPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATS 240
           PPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATS
Sbjct: 181 PPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATS 240

Query: 241 ASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGS 300
           ASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGS
Sbjct: 241 ASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGS 300

Query: 301 LRGRKDVPRSEARPAGRGPR 320
           LRGRKDVPRSEARPAGRGPR
Sbjct: 301 LRGRKDVPRSEARPAGRGPR 320


>gi|113416171 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 265

 Score =  423 bits (1087), Expect = e-118
 Identities = 229/320 (71%), Positives = 232/320 (72%), Gaps = 55/320 (17%)

Query: 1   MSPLETNKGSIGQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVSTATVT 60
           MSPLETNKGSIGQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVSTATVT
Sbjct: 1   MSPLETNKGSIGQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVSTATVT 60

Query: 61  SSGASAPGSADPTLGSTAARRASAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSP 120
           SSGASAPGSADPTLGSTAARRASAPWA  +                              
Sbjct: 61  SSGASAPGSADPTLGSTAARRASAPWACPA----------------------------GC 92

Query: 121 CPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWEKRQDKRLETHPCRAPPL 180
           C   +P PAR                  PR K     EP    +   K   T    A P 
Sbjct: 93  CRANAPAPARN-----------------PRRK-----EPRRQSRATGKSARTRRACASPC 130

Query: 181 PPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATS 240
            P R    P  A    RRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATS
Sbjct: 131 RPGRHCG-PETA----RRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATS 185

Query: 241 ASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGS 300
           ASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGS
Sbjct: 186 ASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGS 245

Query: 301 LRGRKDVPRSEARPAGRGPR 320
           LRGRKDVPRSEARPAGRGPR
Sbjct: 246 LRGRKDVPRSEARPAGRGPR 265


>gi|169166294 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 265

 Score =  418 bits (1075), Expect = e-117
 Identities = 227/320 (70%), Positives = 230/320 (71%), Gaps = 55/320 (17%)

Query: 1   MSPLETNKGSIGQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVSTATVT 60
           MSPLETNKGSI QSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVSTATVT
Sbjct: 1   MSPLETNKGSISQSAIPRFHLRSPGRRGTAGNLPRRLPLAQGSPRCCRFCKGSVSTATVT 60

Query: 61  SSGASAPGSADPTLGSTAARRASAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSP 120
           S GASAPGSADPTLGSTAARRASAPWA  +                              
Sbjct: 61  SFGASAPGSADPTLGSTAARRASAPWACPA----------------------------GC 92

Query: 121 CPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWEKRQDKRLETHPCRAPPL 180
           C   +P PAR                  PR K     EP    +   K   T    A P 
Sbjct: 93  CRANAPAPARN-----------------PRRK-----EPRRQSRATGKSARTRRACASPC 130

Query: 181 PPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATS 240
            P R    P  A    RRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATS
Sbjct: 131 RPGRHCG-PETA----RRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATS 185

Query: 241 ASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGS 300
           ASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGS
Sbjct: 186 ASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGS 245

Query: 301 LRGRKDVPRSEARPAGRGPR 320
           LRGRKDVPRSEARPAGRGPR
Sbjct: 246 LRGRKDVPRSEARPAGRGPR 265


>gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 370

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 92/339 (27%), Positives = 115/339 (33%), Gaps = 76/339 (22%)

Query: 3   PLETNKGSIGQSAIPRFHLRSP------------------GRRGTA-----GNLPRRLPL 39
           P+    G   +S I + H RSP                  GRR        G LP    L
Sbjct: 32  PIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPGAAAL 91

Query: 40  AQGS--PRCCRFCKGSVSTATVTSSGA---------SAPGSADPTLGSTAARRAS-APWA 87
             G+  PR  R  +   S A +   GA           P    P L +     AS AP  
Sbjct: 92  GAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAP-- 149

Query: 88  SLSTRADSGLRHLDRLRKAARLLFVNTPHV------RSPCPIRSPLPAREDPPLSPQHWG 141
               R DS    L RLR A+  L    P        R+ C    PL  +  P LSP    
Sbjct: 150 --GLRPDSARTRL-RLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQ 206

Query: 142 GEILKFPPREKRASSAEPGHWEKRQDKRLETHPCRAPPLPPARRSPLPRAACAHPRRPRP 201
              ++   R     +  P              PC  PP PPA R+P      AH      
Sbjct: 207 SPGVELHARTLSLPAPSPA-------------PCLPPPAPPAARTP-----SAHSPAHTH 248

Query: 202 LAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATSASLPQETPFA--LSVVWAPRR 259
              T      R L+   P+  GG+  P P+V  R     +   Q +P A    V    R 
Sbjct: 249 FTLTLAEAHTRALT---PARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVPSTARA 305

Query: 260 RSQGDARGRRTGVPCA--KRPPAGWLAAAVTSWSPASRR 296
           RS G  RG R   P A  +R P+G      TSW   +RR
Sbjct: 306 RSPGARRGARELAPRAGRRRQPSG-----RTSWRRRARR 339


>gi|239748995 PREDICTED: hypothetical protein XP_002346877 [Homo
           sapiens]
          Length = 326

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 73/240 (30%), Positives = 90/240 (37%), Gaps = 49/240 (20%)

Query: 7   NKGSIGQSAIPRFHLRS------PGRRGTAGNL-PRRLPL--AQGSPRCCRFCKGSVSTA 57
           N G + Q   PR    +      P RR    +  PRRLP    QGS   C F      T 
Sbjct: 81  NNGKVQQDRFPRGASPAWPGPPTPARRPVGAHACPRRLPAWRVQGSSPPCCFPASQQITN 140

Query: 58  TVTSSGASAPGSADPTLGSTAA-------RRASAPW-ASLSTRADSGLRHLD-----RLR 104
           T  S G    G A  +LG  A        R A +P  A  + RA   L+ L       LR
Sbjct: 141 TERSHGGDGRGVARASLGDKAGAGRAGRGRPAQSPAEADAAARASKSLKLLSSALPPHLR 200

Query: 105 KAARLLFVNTPHVR-SPCPIRS------PLPAREDPPLS----PQHWGGEILKFPP---R 150
            AA+   V  P  + SP  +R+      P P R DP  S    P H G   L+ PP   R
Sbjct: 201 PAAKTRAVAGPTAKESPPALRTVGDGPRPGPKRPDPAPSRLPPPPHAGA--LRGPPLPHR 258

Query: 151 EKRASSAEPGHW--------EKRQDKRLETHPC---RAPPLPPARRSPLPRAACAHPRRP 199
            +R+   E G          E  +++     P    R P   PA    LP   CA P RP
Sbjct: 259 LRRSHFREVGGGCADSVVLAEPSREQAHAAPPAWRTRVPGAGPAPPLGLPSLLCADPHRP 318


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 60/221 (27%), Positives = 74/221 (33%), Gaps = 17/221 (7%)

Query: 112  VNTPHVRSPCPIRSPLPAREDPPLSPQHWGGEILKFP---PREKRASSAEPGHWEKRQDK 168
            V  P   +P P    LP  ++ P +P       L      P++ RA+ A  G       K
Sbjct: 878  VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPK 937

Query: 169  RLETHPCRAPPLP---PARRSP--LPRAACAHPRRPRPLAGTTFCGGARVL-SNPPPSGS 222
               T P   PP P   PA  SP   P    A P  P+    T    GA    +  PPS  
Sbjct: 938  GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK 997

Query: 223  GGDARPS----PLVPRRCRATSASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRP 278
            GG A PS    P  P     +    P  TPF       P   +    +G     P  K  
Sbjct: 998  GGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS-TPPAATPPSPKGSPAATPLPKGA 1056

Query: 279  PAGWLAAAVTSWSPASRRNPGSLRGRKDVPRSEARPAGRGP 319
            P      A T  SP       SL+G    P +       GP
Sbjct: 1057 PT---TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094



 Score = 36.2 bits (82), Expect = 0.040
 Identities = 35/121 (28%), Positives = 46/121 (38%), Gaps = 15/121 (12%)

Query: 119  SPCPIRSPLPAREDPPLSPQHWGGEI--LKFPPREKRASSAEPGHWEKRQDKRLETHPCR 176
            +P P  +  P+ +  P +P   G        PP  K + +A P        K   T P  
Sbjct: 985  APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF------PKGASTPPAA 1038

Query: 177  APPLPPAR--RSPLPRAACAHPRR--PRPLAGT---TFCGGARVLSNPPPSGSGGDARPS 229
             PP P      +PLP+ A   P    P P  G    +  G     +  PPS  GG A PS
Sbjct: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS 1098

Query: 230  P 230
            P
Sbjct: 1099 P 1099



 Score = 33.1 bits (74), Expect = 0.34
 Identities = 63/239 (26%), Positives = 81/239 (33%), Gaps = 38/239 (15%)

Query: 38   PLAQGSPRCCRFCKGSVST------------ATVTSSGASAPGSADPTL-----GSTAAR 80
            P  +GSP      KG+ +T            AT +  GA  P +A P        + + +
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100

Query: 81   RASAPWASLSTRADSGLRHLDRLRKAARLLFVNTPH-----VRSPCPIRSPLPAREDPPL 135
             A  P A+       GL       K A      TP      + +P P  +P      PP 
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPH--KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP- 1157

Query: 136  SPQHWGGEILKFPPREKRASSAEP----GHWEKRQDKRLETHPCRAPPLPPAR-RSPLPR 190
            SP+  GG     P       +A P    G       K   T P   PP P     +P P+
Sbjct: 1158 SPK--GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215

Query: 191  AACAHPRRPRP-----LAGTTFCGGARVLSNPPPSGSGGDARPSPL-VPRRCRATSASL 243
             A   P    P     LA  +  G     +  PPS  GG A P P   P    AT  SL
Sbjct: 1216 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL 1274



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 65/276 (23%), Positives = 92/276 (33%), Gaps = 30/276 (10%)

Query: 57   ATVTSSGASAPGSADPTLG----STAARRASAPWASLSTRADSGLRHLDRLRKAARLLFV 112
            AT +  GA  P +A P       +T + + +    +++  +  G        K A     
Sbjct: 978  ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037

Query: 113  NTPHVRSPCPIRSPLP--AREDPPLS-PQHWGGEI---LKFPPREKRASSAEPGHWEKRQ 166
             TP      P  +PLP  A   P  + P   GG     LK  P    A+   P       
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA-- 1095

Query: 167  DKRLETHPCRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFC-------GGARVLSNPPP 219
                 T   +  P+PPA   P P+   A P  P   A TT         GG   L+ PPP
Sbjct: 1096 -----TPSPKGAPMPPAATPPSPKGGLATP--PHKGAPTTPAATPPSPKGG---LATPPP 1145

Query: 220  SGSGGDARPSPLVPRRCRATSASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPP 279
             G+      +P  P+   AT       T  A +        +    +G  T        P
Sbjct: 1146 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205

Query: 280  AGWLAAAVTSWSPAS-RRNPGSLRGRKDVPRSEARP 314
             G LA      +P +    P S +G    P  +  P
Sbjct: 1206 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241



 Score = 30.8 bits (68), Expect = 1.7
 Identities = 59/251 (23%), Positives = 81/251 (32%), Gaps = 57/251 (22%)

Query: 119  SPCPIRSPLPAREDPP------LSPQHWGGE--ILKFPPREKRASSAEPGHWEKRQDKRL 170
            +P P  +P P    PP       +P H G     +  PP  K   +  P           
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316

Query: 171  ETHPCRAP--------PLPPARRSPLPRAACAHP----------------RRPRPLAGTT 206
               P  +P        P PPA   P P+     P                  P P A T 
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376

Query: 207  FCGGARVLSNPPPSGSGGDARPS-----------PLVPRRCRAT-----SASLPQE---T 247
               G   ++  PPS   G A PS           PL P++  AT      A+ P +   T
Sbjct: 1377 SHKGGPAMT--PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434

Query: 248  PFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGSLRGRKDV 307
            P A++ V   +  +    +G     P +K  P      AVT  SP     P  +      
Sbjct: 1435 PPAVTPVSLKKAPATSAPKG-GPATPSSKGDPT---LPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 308  PRSEARPAGRG 318
             ++ A PA  G
Sbjct: 1491 KKAPATPAPMG 1501


>gi|239755634 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 449

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 83/328 (25%), Positives = 103/328 (31%), Gaps = 86/328 (26%)

Query: 29  TAGNLPRRLPLAQGSPRCCRFCKGSVSTATVTSSGASAPGSADPTLGST------AARRA 82
           T G  PR  P A  S    +     V     +  GAS    +  T G         A  A
Sbjct: 111 TLGQAPRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKRRESWRTDGERLRSGRGCAGAA 170

Query: 83  SAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSPCPIRSPLPAREDPPLSPQHWGG 142
             P ASL TR +   R     R  AR L        S  P          PPL       
Sbjct: 171 RGPDASLDTRREGWPRAAVVGRHEARRLKPGVSVSSSLSP---------GPPLQRSSSLN 221

Query: 143 EILKFPPREKRASSAEPGHWEKRQDKRL-------------ETHPCRAPPLPPARRSPLP 189
           E L+       +S+ E G   +R ++R                HP R  PLPP RR P P
Sbjct: 222 ETLRSAAAHAESSARECGKRTQRPEQRFLCRGSSFCGHRPQRLHPGR--PLPPQRRPPGP 279

Query: 190 RAACAHPRRPRPLAGTTFCGGARVLSNPP---PSG---SGGDARPSPLVPRRCRATSASL 243
             A A              G  R  + PP   PS        A P+PL  R         
Sbjct: 280 APAAA--------------GATRGTAAPPGRDPSAWFLDSASACPTPLAARS-------- 317

Query: 244 PQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGSLRG 303
                      W P   ++   RG+  G   A RP  G  +    +W P   R  G  R 
Sbjct: 318 -----------WHPFVANKLCGRGKGAG-GGASRPKEGVGSGRARAWEPRGGRESGRSRR 365

Query: 304 RK----------------DVPRSEARPA 315
           RK                +VPR  +RP+
Sbjct: 366 RKSLLEDLQTEATLWPSREVPREPSRPS 393


>gi|239744429 PREDICTED: hypothetical protein XP_002343157 [Homo
           sapiens]
          Length = 449

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 83/328 (25%), Positives = 103/328 (31%), Gaps = 86/328 (26%)

Query: 29  TAGNLPRRLPLAQGSPRCCRFCKGSVSTATVTSSGASAPGSADPTLGST------AARRA 82
           T G  PR  P A  S    +     V     +  GAS    +  T G         A  A
Sbjct: 111 TLGQAPRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKRRESWRTDGERLRSGRGCAGAA 170

Query: 83  SAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSPCPIRSPLPAREDPPLSPQHWGG 142
             P ASL TR +   R     R  AR L        S  P          PPL       
Sbjct: 171 RGPDASLDTRREGWPRAAVVGRHEARRLKPGVSVSSSLSP---------GPPLQRSSSLN 221

Query: 143 EILKFPPREKRASSAEPGHWEKRQDKRL-------------ETHPCRAPPLPPARRSPLP 189
           E L+       +S+ E G   +R ++R                HP R  PLPP RR P P
Sbjct: 222 ETLRSAAAHAESSARECGKRTQRPEQRFLCRGSSFCGHRPQRLHPGR--PLPPQRRPPGP 279

Query: 190 RAACAHPRRPRPLAGTTFCGGARVLSNPP---PSG---SGGDARPSPLVPRRCRATSASL 243
             A A              G  R  + PP   PS        A P+PL  R         
Sbjct: 280 APAAA--------------GATRGTAAPPGRDPSAWFLDSASACPTPLAARS-------- 317

Query: 244 PQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGSLRG 303
                      W P   ++   RG+  G   A RP  G  +    +W P   R  G  R 
Sbjct: 318 -----------WHPFVANKLCGRGKGAG-GGASRPKEGVGSGRARAWEPRGGRESGRSRR 365

Query: 304 RK----------------DVPRSEARPA 315
           RK                +VPR  +RP+
Sbjct: 366 RKSLLEDLQTEATLWPSREVPREPSRPS 393


>gi|239751929 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 382

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 52/176 (29%), Positives = 62/176 (35%), Gaps = 42/176 (23%)

Query: 181 PPARRSPLPRAACAHPRRPR---------------PLAGTTFCGGARV----LSNPPPSG 221
           PP R  P  R++C  P R R               P       GGAR     +S P P  
Sbjct: 63  PPTRAGPAQRSSCTQPHRRRRRGTRRLPPALTPAGPYHSARPGGGARARAARVSPPTPPR 122

Query: 222 SGGD---ARPSPLVPRRCRATSASLPQETPFALSVVWAPRRR------------SQGDAR 266
           SG D     P+P    RCR T A L   T   LS    P RR            +QG+  
Sbjct: 123 SGLDPAVPSPTPAPLARCRQTRAGLRLSTGGRLS---PPLRRAASGEWKRPGGLTQGEFA 179

Query: 267 GRRT-GVPCAKRP----PAGWLAAAVTSWSPASRRNPGSLRGRKDVPRSEARPAGR 317
           GR   G     RP    P G          PA RR    LR +   P++  R  G+
Sbjct: 180 GRGAGGARVTHRPGRLRPRGRGRGRARRTCPARRRGEEDLRVQDSCPQAGCRAMGQ 235


>gi|239746415 PREDICTED: hypothetical protein XP_002344217 [Homo
           sapiens]
          Length = 382

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 52/176 (29%), Positives = 62/176 (35%), Gaps = 42/176 (23%)

Query: 181 PPARRSPLPRAACAHPRRPR---------------PLAGTTFCGGARV----LSNPPPSG 221
           PP R  P  R++C  P R R               P       GGAR     +S P P  
Sbjct: 63  PPTRAGPAQRSSCTQPHRRRRRGTRRLPPALTPAGPYHSARPGGGARARAARVSPPTPPR 122

Query: 222 SGGD---ARPSPLVPRRCRATSASLPQETPFALSVVWAPRRR------------SQGDAR 266
           SG D     P+P    RCR T A L   T   LS    P RR            +QG+  
Sbjct: 123 SGLDPAVPSPTPAPLARCRQTRAGLRLSTGGRLS---PPLRRAASGEWKRPGGLTQGEFA 179

Query: 267 GRRT-GVPCAKRP----PAGWLAAAVTSWSPASRRNPGSLRGRKDVPRSEARPAGR 317
           GR   G     RP    P G          PA RR    LR +   P++  R  G+
Sbjct: 180 GRGAGGARVTHRPGRLRPRGRGRGRARRTCPARRRGEEDLRVQDSCPQAGCRAMGQ 235


>gi|239754657 PREDICTED: hypothetical protein XP_002346062 [Homo
           sapiens]
          Length = 384

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 76/267 (28%), Positives = 89/267 (33%), Gaps = 67/267 (25%)

Query: 62  SGASAPGSADPTLGSTA----ARRASAPWASLSTRADSGLRHLDRLRK------------ 105
           SG    GS   T G  A     RRA+   ++      SG   L R RK            
Sbjct: 4   SGPGPGGSYPITFGCGARACGGRRANFSLSAAFRTCSSGTCRLTRSRKSRLERGTFSPES 63

Query: 106 AARLLFVNTPHV--RSPCPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWE 163
           AA       PH   R+    R P P    PP      G      PPR  +  S       
Sbjct: 64  AAGTEVSGAPHPDSRTRPAARPPHPRTRSPP-GRSGSGTTFSAVPPRPSQHQSGS----- 117

Query: 164 KRQDKRLETHPCRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSG 223
               +     P   P    AR SP P A  A     R   G    GG    S P   G G
Sbjct: 118 ----RLRPAAPGPRPGCSSARASPAPAAPQA---AARTAPGRAASGG----SGPGSRGQG 166

Query: 224 GD---ARPS-------PLVPRRCRATSASLPQETPFALSVVWAPRRRSQGDARGRRTGVP 273
            D   ARPS       PL  RRCRA                 APRR ++     RR G+P
Sbjct: 167 SDQVGARPSRAGGQPPPLTCRRCRA-----------------APRRSARPF---RRPGLP 206

Query: 274 CAKRPPAGWLAAAVTSWSPASRRNPGS 300
              RP +G  A +  +W   S   PG+
Sbjct: 207 LKSRPGSGTGARSCGTW--GSGGGPGT 231


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 91/357 (25%), Positives = 122/357 (34%), Gaps = 50/357 (14%)

Query: 3   PLETNKGSIGQSAIPRFHLRSPGRR--GTAGNLPRRLPLAQG----SPRCCRFCKGSVST 56
           PL    G IG + IP    R+   R  GT+   P   P A G    +P       G VS+
Sbjct: 57  PLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116

Query: 57  ATVTSSGASAPG---------SADPTLG---STAARRASAPWASLSTRADSGLRHLDRLR 104
               +SG + PG         SA+ T+    +T A + SA  A                 
Sbjct: 117 PG-RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175

Query: 105 KAARLLFVNTP-HVRSPCPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWE 163
            A R     T   +  P P   P P  E P  S           P    R   +  G  +
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235

Query: 164 KRQDKRLETHPCRAPPLPPARRSPLPRA---ACAHPRRPRPLAGTTFCGGARV------- 213
           +   + L +     P   PAR  P  R    A AHP +P+P  G       +V       
Sbjct: 236 RPASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQVTPPRKDA 292

Query: 214 ------LSNPP---PSGSGGDARPSPLVPRRCRATSASLPQETPFALSVVWAPRRRSQGD 264
                 LS+ P   PS SG  ARP P          A+LP   P A  +  AP   S   
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP 352

Query: 265 ARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGSLRGRK--DVPRSEARPAGRGP 319
           +      +     PPA   + A  S +    + P SL+      VP S   P+ + P
Sbjct: 353 S------LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 48/196 (24%), Positives = 71/196 (36%), Gaps = 27/196 (13%)

Query: 70  ADPTLGSTAARRASAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSPCPIRS-PLP 128
           A P+L +  A   + P  +L + A   L+          L    TP   +PCP+++ P P
Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL---ETPPCPAPCPLQAPPSP 575

Query: 129 AREDPPLSPQHWGGEILKFPPREKRASSAEP------------GHWEKRQDKRLETHPCR 176
               PP +P      I   PP+   A ++ P                 +    L   P +
Sbjct: 576 LTTPPPETP----SSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ 631

Query: 177 APPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRRC 236
           APP PPA   PL   A   P+ P  LA            +PP           P+ P   
Sbjct: 632 APPSPPA-SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP--- 687

Query: 237 RATSASLPQETPFALS 252
              SA+ P + P +L+
Sbjct: 688 ---SATPPSQAPPSLA 700



 Score = 35.4 bits (80), Expect = 0.068
 Identities = 44/156 (28%), Positives = 54/156 (34%), Gaps = 22/156 (14%)

Query: 120 PCPIRSP--LPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHW-EKRQDKRLETHPCR 176
           P P  SP   P+   PP +P       L+ PP    +    P      R    L   P +
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767

Query: 177 APPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGD----------- 225
            PP PPA    LP +  A P    P A  T     + L +PP S  G             
Sbjct: 768 VPPSPPA---SLPMSPLAKPPPQAPPALAT--PPLQALPSPPASFPGQAPFSPSASLPMS 822

Query: 226 --ARPSPLVPRRCRATSASLPQETPFALSVVWAPRR 259
             A P P  P    A    +P   P A   + APRR
Sbjct: 823 PLATPPPQAPPVLAAPLLQVPPSPP-ASPTLQAPRR 857


>gi|239743279 PREDICTED: hypothetical protein XP_002342816 [Homo
           sapiens]
          Length = 384

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 76/267 (28%), Positives = 89/267 (33%), Gaps = 67/267 (25%)

Query: 62  SGASAPGSADPTLGSTA----ARRASAPWASLSTRADSGLRHLDRLRK------------ 105
           SG    GS   T G  A     RRA+   ++      SG   L R RK            
Sbjct: 4   SGPGPGGSYPITFGCGARACGGRRANFSLSAAFRTCSSGTCRLTRSRKSRLERGTFSPES 63

Query: 106 AARLLFVNTPHV--RSPCPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWE 163
           AA       PH   R+    R P P    PP      G      PPR  +  S       
Sbjct: 64  AAGTEVSGAPHPDSRTRPAARPPHPRTRSPP-GRSGSGTTFSAVPPRPSQHQSGS----- 117

Query: 164 KRQDKRLETHPCRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSG 223
               +     P   P    AR SP P A  A     R   G    GG    S P   G G
Sbjct: 118 ----RLRPAAPGPRPGCSSARASPAPAAPQA---AARTAPGRAASGG----SGPGSRGQG 166

Query: 224 GD---ARPS-------PLVPRRCRATSASLPQETPFALSVVWAPRRRSQGDARGRRTGVP 273
            D   ARPS       PL  RRCRA                 APRR ++     RR G+P
Sbjct: 167 SDQVGARPSRAGGQPPPLTCRRCRA-----------------APRRSARPF---RRPGLP 206

Query: 274 CAKRPPAGWLAAAVTSWSPASRRNPGS 300
              RP +G  A +  +W   S   PG+
Sbjct: 207 LKSRPGSGTGARSCGTW--GSGGGPGT 231


>gi|239508962 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 76/267 (28%), Positives = 89/267 (33%), Gaps = 67/267 (25%)

Query: 62  SGASAPGSADPTLGSTA----ARRASAPWASLSTRADSGLRHLDRLRK------------ 105
           SG    GS   T G  A     RRA+   ++      SG   L R RK            
Sbjct: 4   SGPGPGGSYPITFGCGARACGGRRANFSLSAAFRTCSSGTCRLTRSRKSRLERGTFSPES 63

Query: 106 AARLLFVNTPHV--RSPCPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWE 163
           AA       PH   R+    R P P    PP      G      PPR  +  S       
Sbjct: 64  AAGTEVSGAPHPDSRTRPAARPPHPRTRSPP-GRSGSGTTFSAVPPRPSQHQSGS----- 117

Query: 164 KRQDKRLETHPCRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSG 223
               +     P   P    AR SP P A  A     R   G    GG    S P   G G
Sbjct: 118 ----RLRPAAPGPRPGCSSARASPAPAAPQA---AARTAPGRAASGG----SGPGSRGQG 166

Query: 224 GD---ARPS-------PLVPRRCRATSASLPQETPFALSVVWAPRRRSQGDARGRRTGVP 273
            D   ARPS       PL  RRCRA                 APRR ++     RR G+P
Sbjct: 167 SDQVGARPSRAGGQPPPLTCRRCRA-----------------APRRSARPF---RRPGLP 206

Query: 274 CAKRPPAGWLAAAVTSWSPASRRNPGS 300
              RP +G  A +  +W   S   PG+
Sbjct: 207 LKSRPGSGTGARSCGTW--GSGGGPGT 231


>gi|38569493 potassium voltage-gated channel, subfamily H
            (eag-related), member 3 [Homo sapiens]
          Length = 1083

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 51/176 (28%), Positives = 61/176 (34%), Gaps = 35/176 (19%)

Query: 100  LDRLRKAARLLFVNTPHVRSPCPIRS---PLPARED---PPLSPQHWGGEILKFPPREKR 153
            L  LR+A +L+    PH   PCP  S   P PA       PL            PP    
Sbjct: 899  LQSLRQAVQLVLA--PHREGPCPRASGEGPCPASTSGLLQPLCVDTGASSYCLQPP---- 952

Query: 154  ASSAEPGHWEKRQDKRLETHPCRAPPL---------PPARRSPLPRAAC--AHPRRPRPL 202
            A S   G W          HP   PP          P ++ SP PRA           P 
Sbjct: 953  AGSVLSGTWP---------HPRPGPPPLMAPWPWGPPASQSSPWPRATAFWTSTSDSEPP 1003

Query: 203  AGTTFCGGARVLSNPPPSGSGGDARPSPLVP-RRCRATSASLPQETPFALSVVWAP 257
            A    C      ++PPPS  G  AR  P  P  +  ATS   P      L++ W P
Sbjct: 1004 ASGDLCSEPSTPASPPPSEEG--ARTGPAEPVSQAEATSTGEPPPGSGGLALPWDP 1057


>gi|169214061 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 55/186 (29%), Positives = 74/186 (39%), Gaps = 29/186 (15%)

Query: 124 RSPLPAREDPPLSPQHWGGEIL---KFPPREKRASS----AEPGHWEKRQDKRLETHPCR 176
           RSPL A +     P  WG  +L   +  PR    SS     + G   +R  +  +  P R
Sbjct: 101 RSPLKAAQQDRGLPA-WGVWLLSRAEVRPRSALGSSRRGLGDKGPRSRRAAEFTQARPTR 159

Query: 177 APPLPPARRSPLPRAAC--AHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPR 234
               P   R   P A C   + R+ R  AG    G    L+ P P+GS     P P  P 
Sbjct: 160 KRRTPGGGR---PEAGCWLENRRQRRRKAGAERAGAGPTLTPPLPAGS-----PDPPSP- 210

Query: 235 RCRATSASLPQETPFALSVVW--APRRRSQGDARGRRTGVPCAKR---PPAGWLAAAVTS 289
              AT+A  P++ P      W   PRRR +   R   +   C+ R   P +G  AA   S
Sbjct: 211 --AATAAPQPEQRPHLSRGQWRLLPRRRPE---RAAGSAGSCSSRRALPASGSGAAMTGS 265

Query: 290 WSPASR 295
           W+   R
Sbjct: 266 WAAPPR 271


>gi|169214437 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 55/186 (29%), Positives = 74/186 (39%), Gaps = 29/186 (15%)

Query: 124 RSPLPAREDPPLSPQHWGGEIL---KFPPREKRASS----AEPGHWEKRQDKRLETHPCR 176
           RSPL A +     P  WG  +L   +  PR    SS     + G   +R  +  +  P R
Sbjct: 101 RSPLKAAQQDRGLPA-WGVWLLSRAEVRPRSALGSSRRGLGDKGPRSRRAAEFTQARPTR 159

Query: 177 APPLPPARRSPLPRAAC--AHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPR 234
               P   R   P A C   + R+ R  AG    G    L+ P P+GS     P P  P 
Sbjct: 160 KRRTPGGGR---PEAGCWLENRRQRRRKAGAERAGAGPTLTPPLPAGS-----PDPPSP- 210

Query: 235 RCRATSASLPQETPFALSVVW--APRRRSQGDARGRRTGVPCAKR---PPAGWLAAAVTS 289
              AT+A  P++ P      W   PRRR +   R   +   C+ R   P +G  AA   S
Sbjct: 211 --AATAAPQPEQRPHLSRGQWRLLPRRRPE---RAAGSAGSCSSRRALPASGSGAAMTGS 265

Query: 290 WSPASR 295
           W+   R
Sbjct: 266 WAAPPR 271


>gi|169213353 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 384

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 55/186 (29%), Positives = 74/186 (39%), Gaps = 29/186 (15%)

Query: 124 RSPLPAREDPPLSPQHWGGEIL---KFPPREKRASS----AEPGHWEKRQDKRLETHPCR 176
           RSPL A +     P  WG  +L   +  PR    SS     + G   +R  +  +  P R
Sbjct: 101 RSPLKAAQQDRGLPA-WGVWLLSRAEVRPRSALGSSRRGLGDKGPRSRRAAEFTQARPTR 159

Query: 177 APPLPPARRSPLPRAAC--AHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPR 234
               P   R   P A C   + R+ R  AG    G    L+ P P+GS     P P  P 
Sbjct: 160 KRRTPGGGR---PEAGCWLENRRQRRRKAGAERAGAGPTLTPPLPAGS-----PDPPSP- 210

Query: 235 RCRATSASLPQETPFALSVVW--APRRRSQGDARGRRTGVPCAKR---PPAGWLAAAVTS 289
              AT+A  P++ P      W   PRRR +   R   +   C+ R   P +G  AA   S
Sbjct: 211 --AATAAPQPEQRPHLSRGQWRLLPRRRPE---RAAGSAGSCSSRRALPASGSGAAMTGS 265

Query: 290 WSPASR 295
           W+   R
Sbjct: 266 WAAPPR 271


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 59/216 (27%), Positives = 78/216 (36%), Gaps = 27/216 (12%)

Query: 119 SPCPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWEKRQDKRLETHPCR-- 176
           SP    SP P +     SP+         PP  +R S   P      + +R  T P R  
Sbjct: 524 SPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS---PSPAPPPRRRRTPTPPPRRR 580

Query: 177 APPLPPARRSPLPRAACAHPRR---PRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVP 233
            P  PP RRSP PR      +R   P P          R  S PPP       R SP  P
Sbjct: 581 TPSPPPRRRSPSPRRYSPPIQRRYSPSPPP------KRRTASPPPPP----KRRASPSPP 630

Query: 234 RRCRATSASLPQETPFALSVVWAPRRRSQ--------GDARGRRTGVPCAKRPPAGWLAA 285
            + R + +  P++    ++   +P   S+           R  R+  P  +  P+    A
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690

Query: 286 AVTSWSPAS-RRNPGSLRGRKDVPRSEARPAGRGPR 320
             TS SP   RR   S   R+  P    RP  R  R
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 37/134 (27%), Positives = 46/134 (34%), Gaps = 24/134 (17%)

Query: 118 RSPCPIRSPLPAREDPPL----SPQHWGGEILKFPPREKRASSAEPGHWEKRQDKRLETH 173
           R P P R P P R  PP      P+H      + P R +R SSA                
Sbjct: 313 RRPSPRRRPSPRRRTPPRRMPPPPRH---RRSRSPVRRRRRSSASLSGSSSSSSSSRSRS 369

Query: 174 PCRAPP----LPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPS 229
           P + PP     PP +   L  +A    RR RP    T          PPP        P+
Sbjct: 370 PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPAT----------PPPKTRHS---PT 416

Query: 230 PLVPRRCRATSASL 243
           P    R R +  S+
Sbjct: 417 PQQSNRTRKSRVSV 430



 Score = 33.9 bits (76), Expect = 0.20
 Identities = 40/156 (25%), Positives = 64/156 (41%), Gaps = 18/156 (11%)

Query: 119 SPCPIRSPLPAREDPPLSPQHWGGEILKFPP--------REKRASSAEPGHWEKRQDKRL 170
           SP P  +P P + +   S +  GG++             R+ + SS++ G     +D+R 
Sbjct: 450 SPSP--APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERP 507

Query: 171 ETHPCRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSP 230
           +    +   +   RR    R+A   PR+ +    T+  G  R   +PPP+       P+P
Sbjct: 508 KRSHVKNGEVGRRRRHSPSRSASPSPRKRQ--KETSPRGRRRRSPSPPPTRRRRSPSPAP 565

Query: 231 LVPRRCRATSASLPQETPFALSVVWAPRRRSQGDAR 266
             PRR R  +    + TP        PRRRS    R
Sbjct: 566 -PPRRRRTPTPPPRRRTPSP-----PPRRRSPSPRR 595



 Score = 32.3 bits (72), Expect = 0.58
 Identities = 48/172 (27%), Positives = 64/172 (37%), Gaps = 17/172 (9%)

Query: 150 REKRASSAEPGHWEKRQDKRLETHPCRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCG 209
           R   + SA P   +++++        R+P  PP RR   P  A    RR  P    T   
Sbjct: 522 RHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTP----TPPP 577

Query: 210 GARVLSNPPPSGSGGDARPSPLVPRRCRATSASLPQETPFALSVVWAPRRRSQGDARGRR 269
             R  S PP   S    R SP + RR    S S P +   A       RR S      RR
Sbjct: 578 RRRTPSPPPRRRSPSPRRYSPPIQRR---YSPSPPPKRRTASPPPPPKRRASPSPPPKRR 634

Query: 270 TGVPCAKRPPAGWLAAAVTSWSPASRRNPG-SLRGRKDVPRSEARPAGRGPR 320
                +  PP    ++ VT      RR+P  S + RK    S +    R P+
Sbjct: 635 V----SHSPPPKQRSSPVT-----KRRSPSLSSKHRKGSSPSRSTREARSPQ 677



 Score = 28.5 bits (62), Expect = 8.3
 Identities = 51/211 (24%), Positives = 71/211 (33%), Gaps = 35/211 (16%)

Query: 122 PIRSPLPAREDP-PLSPQHWGGEILKFPPREK-------RASSAEPGHWEKRQDKRLETH 173
           P   P+P  ++P P        E  K  PR +       R  S  P H   R+  R  + 
Sbjct: 248 PKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSR 307

Query: 174 PCRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGAR-------VLSNPPPSGSGGDA 226
                  P  RR P PR      R P P          R        LS    S S   +
Sbjct: 308 SYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRS 367

Query: 227 RPSPLVPRRCRATSASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAKRPPAGWLAAA 286
           R  P  P +    ++S P++T         PRRR +          P A  PP       
Sbjct: 368 RSPPKKPPK---RTSSPPRKTRRLSPSASPPRRRHRPS--------PPATPPPK------ 410

Query: 287 VTSWSPASRRNPGSLRGRKDVPRSEARPAGR 317
            T  SP  +++  + + R  V  S  R +G+
Sbjct: 411 -TRHSPTPQQSNRTRKSRVSV--SPGRTSGK 438


>gi|239746609 PREDICTED: hypothetical protein XP_002343799 [Homo
           sapiens]
          Length = 245

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 50/171 (29%), Positives = 65/171 (38%), Gaps = 40/171 (23%)

Query: 154 ASSAEPGHWEKRQDKRLETHPCRAP---PLP-PARRSPLPRAACAHPR-RPRPLAGTTFC 208
           A +A   H  + + +R     CR P   P P P R+  L +AA   P  RPRP       
Sbjct: 85  ARNARGKHLRRTRRRRTLGRRCRPPAPRPRPRPRRKLALDQAATRIPAARPRP------- 137

Query: 209 GGARVLSNPPPSGSGGDARPSPLVPRRCRATSASLPQETPFALSVVWAPRRRSQGDARGR 268
                   P P G G   +  P V R  R T ++ P+  P        P RR     R  
Sbjct: 138 --------PGPGGRGSHWKIQPGVQRLPRPTPSAQPRPGP--------PERR-----RAS 176

Query: 269 RTGVPCAKRPPAGWLAAAVTSWSPASRRNPGSLRGRKDVPRSEARPAGRGP 319
           R  + C +     W  AA + W     R PG   G +   R +ARP  R P
Sbjct: 177 RPLIGCGRGGGGTWRRAADSRW-----RRPGG--GFQRSRREKARPPRRLP 220


>gi|13376335 hypothetical protein LOC79946 [Homo sapiens]
          Length = 257

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 46/171 (26%), Positives = 57/171 (33%), Gaps = 22/171 (12%)

Query: 148 PPREKRASSAEPGHWEKRQD----KRLETHPCRAPPLPPARRSPLPRAACAHPRRPRPLA 203
           P     AS+A P H   R+      R    PC  P  PPA R       C  PRR  P A
Sbjct: 100 PHGNTTASTAPPRHPRPRRPGGPALRPTPRPCAGPAPPPASRD----CRCRRPRR-WPRA 154

Query: 204 GTTFCGGARVLSNPPPSGSGGDARPSPLVPRRCRATSASLPQETPFALSVVWAPRRRSQG 263
           G    G       P  +G+   AR +PL   R     +   +  P       +P   +  
Sbjct: 155 GRR--GRRAGACKPSCAGAAWSARGAPLCSYRTSCAGSCGARTAPTPAPTCASPSAAASS 212

Query: 264 DARGRRTGVPCAKRPPAGWLAAAVTSWSPASRRNPGSLRGRKDVPRSEARP 314
             R RR        P   W  A     + A+   PG        PRS A P
Sbjct: 213 CCRRRR----ACSSPTTAWSGACGAGPTAATAAQPGK-------PRSAAAP 252


>gi|239751186 PREDICTED: WD repeat domain 81 [Homo sapiens]
          Length = 2240

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 75/289 (25%), Positives = 100/289 (34%), Gaps = 74/289 (25%)

Query: 52  GSVSTATVTSSGASAPGSADPTLGSTAARRASAPW--ASLSTRADSGLRHLDRLR---KA 106
           G+V+  T   +G   PG A P   +  A R S P   A   TR     R   RLR     
Sbjct: 139 GNVAPPTRGPTGPR-PGPASPGALALIALRVSDPLRKALRQTRVLKSRRKPRRLRLQCML 197

Query: 107 ARLLFVNTPHVRSPCPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWEKRQ 166
            R++   TP    P  +  P  +R  P L+P    G +            A PG  + R+
Sbjct: 198 VRVVLSLTPSFPEPSALSDP--SRWSPVLAP----GSLCP----------AAPGAQDPRR 241

Query: 167 DKRLETHPCRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPS------ 220
            KR    P R   LP A  +P P    + PRRP    GT     +R ++   P+      
Sbjct: 242 GKRAPRPPLRRRRLPAAASAPAPVPRPSQPRRP----GTPEAVASRAVAGLSPALPPGGL 297

Query: 221 -----GSGG------------DARPSPLVPRRCRATSASL---PQE---TPFALSVV--- 254
                GSGG             + PSP +    R+    L   P++    P    VV   
Sbjct: 298 EEMAQGSGGREGALRTPAGGWHSPPSPDMQELLRSVERDLSIDPRQLAPAPGGTHVVALV 357

Query: 255 ---W-------------APRRRSQGDARGRRTGVPCAKRPPAGWLAAAV 287
              W              PR    G+A  R       +R PAGW    V
Sbjct: 358 PARWLASLRDRRLPLGPCPRAEGLGEAEVRTLLQRSVQRLPAGWTRVEV 406


>gi|239753883 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 296

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 51/170 (30%), Positives = 61/170 (35%), Gaps = 28/170 (16%)

Query: 177 APPLPPARRSPLPRAACAHP----RRPRPLAG-----TTFCGGARVLSNPP----PSGSG 223
           +PP P + R+ L   + A      R  R   G     TT  G AR     P    P GS 
Sbjct: 80  SPPRPGSARTQLVATSAAQAAAAGRAQRVRRGLLRWRTTALGPARPRLRRPRHRLPGGSR 139

Query: 224 GDARPSPLVP-------RRCRATSASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAK 276
               P P  P       R  R  +AS+ +  P          R S    RG R G+P   
Sbjct: 140 RLPAPGPRAPAPGKGRERELRTGAASIDR-APARTGPEDLAARASTRRPRGFRPGLPVPT 198

Query: 277 RPPAGWLAAAVTSWSPASRRNPGSLRG-------RKDVPRSEARPAGRGP 319
            PP G  AAA    S A+R    S RG        + VP   A   G GP
Sbjct: 199 APPGGLAAAAKDETSCAARERGASPRGDAGRVGRTRAVPSCGAPAVGTGP 248


>gi|239748442 PREDICTED: hypothetical protein XP_002346660 [Homo
           sapiens]
          Length = 296

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 51/170 (30%), Positives = 61/170 (35%), Gaps = 28/170 (16%)

Query: 177 APPLPPARRSPLPRAACAHP----RRPRPLAG-----TTFCGGARVLSNPP----PSGSG 223
           +PP P + R+ L   + A      R  R   G     TT  G AR     P    P GS 
Sbjct: 80  SPPRPGSARTQLVATSAAQAAAAGRAQRVRRGLLRWRTTALGPARPRLRRPRHRLPGGSR 139

Query: 224 GDARPSPLVP-------RRCRATSASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAK 276
               P P  P       R  R  +AS+ +  P          R S    RG R G+P   
Sbjct: 140 RLPAPGPRAPAPGKGRERELRTGAASIDR-APARTGPEDLAARASTRRPRGFRPGLPVPT 198

Query: 277 RPPAGWLAAAVTSWSPASRRNPGSLRG-------RKDVPRSEARPAGRGP 319
            PP G  AAA    S A+R    S RG        + VP   A   G GP
Sbjct: 199 APPGGLAAAAKDETSCAARERGASPRGDAGRVGRTRAVPSCGAPAVGTGP 248


>gi|239742378 PREDICTED: hypothetical protein XP_002342507 [Homo
           sapiens]
          Length = 296

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 51/170 (30%), Positives = 61/170 (35%), Gaps = 28/170 (16%)

Query: 177 APPLPPARRSPLPRAACAHP----RRPRPLAG-----TTFCGGARVLSNPP----PSGSG 223
           +PP P + R+ L   + A      R  R   G     TT  G AR     P    P GS 
Sbjct: 80  SPPRPGSARTQLVATSAAQAAAAGRAQRVRRGLLRWRTTALGPARPRLRRPRHRLPGGSR 139

Query: 224 GDARPSPLVP-------RRCRATSASLPQETPFALSVVWAPRRRSQGDARGRRTGVPCAK 276
               P P  P       R  R  +AS+ +  P          R S    RG R G+P   
Sbjct: 140 RLPAPGPRAPAPGKGRERELRTGAASIDR-APARTGPEDLAARASTRRPRGFRPGLPVPT 198

Query: 277 RPPAGWLAAAVTSWSPASRRNPGSLRG-------RKDVPRSEARPAGRGP 319
            PP G  AAA    S A+R    S RG        + VP   A   G GP
Sbjct: 199 APPGGLAAAAKDETSCAARERGASPRGDAGRVGRTRAVPSCGAPAVGTGP 248


>gi|239741753 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 274

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 39/119 (32%), Positives = 47/119 (39%), Gaps = 22/119 (18%)

Query: 152 KRASSAEPGHWEKRQDKRLETHPC-RAPPLPPARRSPLPRAACAHPRRPRPLAGT----- 205
           +RAS    G  +K Q++         APP PP +  P P     H  RPRP  GT     
Sbjct: 65  QRASLLPGGSADKDQEREPSLAARGTAPPAPPRQCLPTPCPPLGHGLRPRPPPGTPPPRC 124

Query: 206 --TFCGGARVLSNPPP-----SGSGGDA-----RPSPLVPRRCRATSASLPQETPFALS 252
             T   G R L   PP     +G  G A     RP P   RR R +    P   PF L+
Sbjct: 125 PRTLAPGPRGLFPAPPPAPARTGPAGKAAADRGRPGPAAGRRVRRS----PSFPPFLLA 179


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 54/199 (27%), Positives = 65/199 (32%), Gaps = 19/199 (9%)

Query: 62  SGASAPGSADPTLGSTAARRASAPWASLSTRADSGLRHLDRLRKAARLLFVNTPHVRSPC 121
           S  S P    PT     A R S P   L         HL R  + + L         SP 
Sbjct: 447 SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506

Query: 122 PIRSPLPAREDPPLSPQHWGG-----EILKFPPREKRASSAEPGHWEKRQDKRLETHPCR 176
           P  SP    E+ PLSP          E    PP E  AS   P   E       E  P  
Sbjct: 507 PESSPFSPLEESPLSPPEESPPSPALETPLSPPPE--ASPLSPPFEESPLSPPPEELPTS 564

Query: 177 APP-----LPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPL 231
            PP      PP   SP+       P  P P A   F        +PPP         SPL
Sbjct: 565 PPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPP-------EESPL 617

Query: 232 VPRRCRATSASLPQETPFA 250
            P    +  +  P+++P +
Sbjct: 618 SPPPEASRLSPPPEDSPMS 636



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 38/133 (28%), Positives = 54/133 (40%), Gaps = 12/133 (9%)

Query: 117  VRSPCPIRSPLPAREDPPLSPQHWG-GEILKFPPREKRASSAEPGHWEKRQDKRLETHPC 175
            +++P   ++PL  R    + PQ  G G   + PP  +  + + P H +  +     T P 
Sbjct: 2321 LKTPDVFKAPLTPRASQ-VEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSY-TDPY 2378

Query: 176  RAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVPRR 235
              PPL P  + P P + CA P  PR L    F       S  P S     +  SPL PR 
Sbjct: 2379 AQPPLTPRPQPPPPESCCALP--PRSLPSDPF-------SRVPASPQSQSSSQSPLTPRP 2429

Query: 236  CRATSASLPQETP 248
              A +      TP
Sbjct: 2430 LSAEAFCPSPVTP 2442



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 40/142 (28%), Positives = 52/142 (36%), Gaps = 24/142 (16%)

Query: 119  SPCPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEP------GHWEKRQDKRLET 172
            SP P   PL    +P LSPQ    + L  PP     ++A P      G  E     + ++
Sbjct: 909  SPLPEELPLSPSGEPSLSPQLMPPDPLP-PPLSPIITAAAPPALSPLGELEYPFGAKGDS 967

Query: 173  HP--CRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARP-- 228
             P    A P+     SP P A C  P    P+           +  P P    G A P  
Sbjct: 968  DPESPLAAPILETPISPPPEANCTDPEPVPPM-----------ILPPSPGSPVGPASPIL 1016

Query: 229  -SPLVPRRCRATSASL-PQETP 248
              PL P+       SL PQ +P
Sbjct: 1017 MEPLPPQCSPLLQHSLVPQNSP 1038



 Score = 30.0 bits (66), Expect = 2.9
 Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 18/62 (29%)

Query: 170  LETHPCRAPPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPS 229
            L T P   PP+P    SPLP A+     RP+P A             PP  G   D+RP 
Sbjct: 4936 LPTEPLAEPPVP----SPLPLASSPESARPKPRA------------RPPEEGE--DSRPP 4977

Query: 230  PL 231
             L
Sbjct: 4978 RL 4979


>gi|21361699 sphingosine kinase 2 [Homo sapiens]
          Length = 654

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 32/97 (32%), Positives = 39/97 (40%), Gaps = 13/97 (13%)

Query: 145 LKFPPREKRASSAEPGHWEKRQDKRLETHPCRAPPLP--PARRS------PLPRAACAHP 196
           L + P     +S  P H   R    L   P  APP+   P  RS      PLP+ A A P
Sbjct: 376 LSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASP 435

Query: 197 RRPRPLAGTTFCGGARVLSNPPPSGSGGDARPSPLVP 233
             P PL   +  GG      P  +G  G A  +PL P
Sbjct: 436 GSPEPLPILSLNGG-----GPELAGDWGGAGDAPLSP 467


>gi|239741603 PREDICTED: hypothetical protein XP_002342247 [Homo
           sapiens]
          Length = 351

 Score = 39.3 bits (90), Expect = 0.005
 Identities = 43/142 (30%), Positives = 54/142 (38%), Gaps = 28/142 (19%)

Query: 119 SPCPIRSPLPAREDPPLSPQH--WGGEILKFPPREKRASSAEPGH----W--EKRQDKRL 170
           +P    SP P R  PP +P      G +L           A  GH    W   K + +RL
Sbjct: 168 APAARPSPDPGRRPPPAAPAPVVHVGPVLPLLHDPVGVPLAPLGHGGVDWAENKERPRRL 227

Query: 171 ETHPCR-APPLPPARRSPLPRAACAHPRRPRPLAGTTFCGGARVLSNPPPSGSGGDARPS 229
                R  PP P A RS LP  A    RRPRP               P P+       P 
Sbjct: 228 RLRSQRFRPPSPGAARSQLPETA----RRPRP--------------RPRPALPRRAREPQ 269

Query: 230 PLVPRRCRA-TSASLPQETPFA 250
           P   RRCR  T+   P++ P++
Sbjct: 270 PGSGRRCRRDTAVRWPRQAPYS 291


>gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 38.9 bits (89), Expect = 0.006
 Identities = 67/231 (29%), Positives = 84/231 (36%), Gaps = 54/231 (23%)

Query: 114 TPHVRSPCPIRSPLPAREDPPLSPQHWGGEILKFPPREKRASSAEPGHWE-----KRQDK 168
           +PHV      RSP P R     +PQ   G       R +RA++   G        +R   
Sbjct: 45  SPHVTGAAQ-RSPTPGRARA--APQQGDGGA-----RRERAAAESLGTQSATLGPRRGGL 96

Query: 169 RLETHPC-RAPPLP-------------PARRSPLPRAACAHPRRPRPLAGTTFCGGARVL 214
           R  T P   A PLP             P      P +A + P RP PL  TTF       
Sbjct: 97  RSRTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKT 156

Query: 215 SNPPPSGSGGDARPSPLVPRRCRATSASLPQETPFALSVVWAPR-RRSQGDARGRRTGVP 273
           S P PS  G   RP              L       L+   +PR +  +G    RRT   
Sbjct: 157 SAPRPSPGGRRGRP--------------LGAARGTGLNPGLSPRLQEPRGHQSARRTDT- 201

Query: 274 CAKRPPAGWLAAAVTSWSPASRRNPGSLRG----RKDVPRSEARPAGRGPR 320
            A R  AGW     T  +P+ RRN G+ RG    R D  +      G+G R
Sbjct: 202 -ASR--AGW----ATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQR 245


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,865,068
Number of Sequences: 37866
Number of extensions: 1058751
Number of successful extensions: 6965
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 585
Number of HSP's that attempted gapping in prelim test: 6077
Number of HSP's gapped (non-prelim): 1238
length of query: 320
length of database: 18,247,518
effective HSP length: 102
effective length of query: 218
effective length of database: 14,385,186
effective search space: 3135970548
effective search space used: 3135970548
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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