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Search of human proteins with 169166558
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169166558 PREDICTED: similar to hCG18094 [Homo sapiens]
(459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169166558 PREDICTED: similar to hCG18094 [Homo sapiens] 899 0.0
gi|169167297 PREDICTED: similar to hCG18094 [Homo sapiens] 895 0.0
gi|169166473 PREDICTED: similar to hCG18094 [Homo sapiens] 893 0.0
gi|148746195 trichohyalin [Homo sapiens] 73 6e-13
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 66 6e-11
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 66 6e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 63 5e-10
gi|219803769 trichoplein [Homo sapiens] 61 2e-09
gi|14150056 trichoplein [Homo sapiens] 61 2e-09
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 60 3e-09
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 60 3e-09
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 60 3e-09
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 60 3e-09
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 60 3e-09
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 60 3e-09
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 60 3e-09
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 60 3e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 60 4e-09
gi|31982906 cingulin-like 1 [Homo sapiens] 59 9e-09
gi|239756174 PREDICTED: hypothetical protein [Homo sapiens] 59 1e-08
gi|239750672 PREDICTED: hypothetical protein [Homo sapiens] 59 1e-08
gi|239744982 PREDICTED: hypothetical protein [Homo sapiens] 59 1e-08
gi|45439327 periplakin [Homo sapiens] 59 1e-08
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 57 3e-08
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 57 3e-08
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 57 3e-08
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 57 3e-08
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 57 3e-08
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 56 6e-08
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 56 8e-08
>gi|169166558 PREDICTED: similar to hCG18094 [Homo sapiens]
Length = 459
Score = 899 bits (2323), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MPRSCRERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQ 60
MPRSCRERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQ
Sbjct: 1 MPRSCRERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQ 60
Query: 61 ELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQ 120
ELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQ
Sbjct: 61 ELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQ 120
Query: 121 ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTV 180
ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTV
Sbjct: 121 ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTV 180
Query: 181 QEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEM 240
QEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEM
Sbjct: 181 QEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEM 240
Query: 241 SIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRW 300
SIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRW
Sbjct: 241 SIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRW 300
Query: 301 EEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPDWWE 360
EEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPDWWE
Sbjct: 301 EEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPDWWE 360
Query: 361 EPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPARADSFPGL 420
EPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPARADSFPGL
Sbjct: 361 EPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPARADSFPGL 420
Query: 421 HAQLEAQHWLELERSRERRLQALQQGGSGPGPARRLEAA 459
HAQLEAQHWLELERSRERRLQALQQGGSGPGPARRLEAA
Sbjct: 421 HAQLEAQHWLELERSRERRLQALQQGGSGPGPARRLEAA 459
>gi|169167297 PREDICTED: similar to hCG18094 [Homo sapiens]
Length = 459
Score = 895 bits (2312), Expect = 0.0
Identities = 457/459 (99%), Positives = 458/459 (99%)
Query: 1 MPRSCRERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQ 60
MPRSCRERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQ
Sbjct: 1 MPRSCRERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQ 60
Query: 61 ELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQ 120
ELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQ
Sbjct: 61 ELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQ 120
Query: 121 ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTV 180
ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTV
Sbjct: 121 ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTV 180
Query: 181 QEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEM 240
QEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEM
Sbjct: 181 QEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEM 240
Query: 241 SIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRW 300
SIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRW
Sbjct: 241 SIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRW 300
Query: 301 EEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPDWWE 360
EEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPDWWE
Sbjct: 301 EEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPDWWE 360
Query: 361 EPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPARADSFPGL 420
EPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPARAD+FPGL
Sbjct: 361 EPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPARADAFPGL 420
Query: 421 HAQLEAQHWLELERSRERRLQALQQGGSGPGPARRLEAA 459
AQLEAQHWLELERSRERRLQALQQGGSGPGPARRLEAA
Sbjct: 421 QAQLEAQHWLELERSRERRLQALQQGGSGPGPARRLEAA 459
>gi|169166473 PREDICTED: similar to hCG18094 [Homo sapiens]
Length = 459
Score = 893 bits (2307), Expect = 0.0
Identities = 456/459 (99%), Positives = 457/459 (99%)
Query: 1 MPRSCRERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQ 60
MPRSCRERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQ
Sbjct: 1 MPRSCRERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQ 60
Query: 61 ELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQ 120
ELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQ
Sbjct: 61 ELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQ 120
Query: 121 ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTV 180
ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTV
Sbjct: 121 ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTV 180
Query: 181 QEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEM 240
QEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEM
Sbjct: 181 QEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEM 240
Query: 241 SIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRW 300
SIVELRERLALLKENQRRKEEEKRDQIIQGK TKSQELQNMVEQISLCRAAMGRSAALRW
Sbjct: 241 SIVELRERLALLKENQRRKEEEKRDQIIQGKHTKSQELQNMVEQISLCRAAMGRSAALRW 300
Query: 301 EEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPDWWE 360
EEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPDWWE
Sbjct: 301 EEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSPDWWE 360
Query: 361 EPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPARADSFPGL 420
EPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPARAD+FPGL
Sbjct: 361 EPGRLKAGAGWGWRARRAGTGVPGRGWRGDRVRSAAGRYAAAGAGGGGGVPARADAFPGL 420
Query: 421 HAQLEAQHWLELERSRERRLQALQQGGSGPGPARRLEAA 459
AQLEAQHWLELERSRERRLQALQQGGSGPGPARRLEAA
Sbjct: 421 QAQLEAQHWLELERSRERRLQALQQGGSGPGPARRLEAA 459
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 72.8 bits (177), Expect = 6e-13
Identities = 65/295 (22%), Positives = 144/295 (48%), Gaps = 13/295 (4%)
Query: 49 REGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSH 108
R+ ++Q + E+E ++ + ++ + + E Q++ + ++ EEQL E + L+ +
Sbjct: 233 RQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQE 292
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE R Q+ +++ E+++ + + ++ ERR +++ R++ + + E ++ +
Sbjct: 293 EEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLR 352
Query: 169 QTKLAKGRQQTVQEAIEESR--GLLQRRAQAAQEEQRRRCELISQLRAL--ETQPTRKGK 224
+ + + R+Q ++ EE R L+R Q +E+Q RR + + + + L E Q R+ +
Sbjct: 353 REQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 412
Query: 225 L---VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNM 281
L L + E E E + ++ +R++EE+RD + + + T+ E +
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERR 472
Query: 282 VEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQ 336
+Q+ + R L+ EE++ Q+ R QQLRR ER +R ++
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEE------RREQQERREQQLRREQEERREQRLKR 521
Score = 65.1 bits (157), Expect = 1e-10
Identities = 75/302 (24%), Positives = 140/302 (46%), Gaps = 40/302 (13%)
Query: 48 LREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLS 107
LR +R+ E+ +++ K + E E + K + ++R +QL E R Q +L
Sbjct: 532 LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLK 591
Query: 108 HEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKA 167
E+ Q L +E +R+EQ+ +R E+RL+ + +E +Q+++ ++ +
Sbjct: 592 REQEERLEQRLKREEVERLEQE---------ERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 168 AQTKLAKGRQQTVQEAI--EESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKL 225
Q +L + +Q+ ++ + EE L++R + EE+RR EL A E Q + ++
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQEL-----AEEEQEQARERI 697
Query: 226 VDLTQIPGYGLEGE----MSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNM 281
+ LE E S V R R +E QRR++E++ + +R + ELQ
Sbjct: 698 KSRIPKWQWQLESEADARQSKVYSRPR---KQEGQRRRQEQE-----EKRRRRESELQWQ 749
Query: 282 VEQIS---LCRAAMGRSAALRW--EEK-----KALAAAPAAPSQDERVQQLRRRISERAA 331
E+ + R +W EEK + L+A P P +++R +QLR ++
Sbjct: 750 EEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP--PLREQRERQLRAEERQQRE 807
Query: 332 ER 333
+R
Sbjct: 808 QR 809
Score = 59.3 bits (142), Expect = 7e-09
Identities = 61/290 (21%), Positives = 133/290 (45%), Gaps = 17/290 (5%)
Query: 55 QRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLA 114
Q + +Q+L+R D+ + + + E +++ Q + RE+QL + R + +L +E
Sbjct: 469 QERRKQQLKR-DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER 527
Query: 115 RQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAK 174
Q ++ +Q +Q+E+ +L+ + E+RL ++R + L + E + + + +
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587
Query: 175 GRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGY 234
R + QE E R L + + ++E+RR +L+ E + R+ +L+ +
Sbjct: 588 QRLKREQEERLEQR-LKREEVERLEQEERRE----QRLKREEPEEERRQQLLKSEE---- 638
Query: 235 GLEGEMSIVELRERLALLKEN--QRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAM 292
+ E +LR +E +R +EEE+ +Q ++ + + + Q + E+
Sbjct: 639 --QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARER 696
Query: 293 GRSAALRWE---EKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAAL 339
+S +W+ E +A A S+ + + RRR + R R++ L
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Score = 58.9 bits (141), Expect = 9e-09
Identities = 66/261 (25%), Positives = 118/261 (45%), Gaps = 39/261 (14%)
Query: 79 FEWQKKMQAKDREEQLAAS-----ECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQM 133
+ WQ + + K R L A + R+ Q L EE L R+ +E ++R EQ+++
Sbjct: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE--REKRRRQEQERQYR 931
Query: 134 AKLMLQRAERR-LREDRSRKELVEQVIEGQKNAKAAQ-------TKLAKGRQQTVQEAIE 185
+ LQ+ E + LRE+R ++ E+ + +K+ K Q + K R+Q ++
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYR 991
Query: 186 ESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVEL 245
E L Q Q +EE+ +R + + E Q +K +L E E + E
Sbjct: 992 EEEELQQEEEQLLREEREKR-----RRQEWERQYRKKDELQQ---------EEEQLLREE 1037
Query: 246 RERLALL-KENQRRKEEE--KRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEE 302
RE+ L +E Q R+EEE + ++ + G+ +++ Q + Q + L+ EE
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR-------KEEELQQEE 1090
Query: 303 KKALAAAPAAPSQDERVQQLR 323
++ L P + ER +Q R
Sbjct: 1091 EQLLREEPEKRRRQERERQCR 1111
Score = 58.2 bits (139), Expect = 2e-08
Identities = 68/308 (22%), Positives = 134/308 (43%), Gaps = 42/308 (13%)
Query: 55 QRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLA 114
Q + EQ L+R + E +W K+ + +R EQ E R+ Q K EE
Sbjct: 440 QERREQRLKREQE---------ERRDWLKREEETERHEQ----ERRKQQLKRDQEEERRE 486
Query: 115 RQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAK 174
R ++E ++R +Q++ + L+R + RE R +++ E+ ++ + ++ + +
Sbjct: 487 RWLKLEEEERREQQERREQ---QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE 543
Query: 175 GRQQTVQEAIEESRGLLQRRAQAAQEEQR-RRCELISQLRALETQPTRKGKLVDLTQIPG 233
R++ + + EE R +RR Q + EQ RR +L+ + Q ++ +
Sbjct: 544 ERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ--------- 594
Query: 234 YGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMG 293
E + RE + L++ +RR++ KR++ + +R + + + E+
Sbjct: 595 ---EERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER--------- 642
Query: 294 RSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPR 353
R LR E+++ ++ER++Q +R E ER Q R K R
Sbjct: 643 RQQQLRREQQERREQRLKREEEEERLEQRLKR--EHEEERREQELAEEEQEQARERIKSR 700
Query: 354 VSPDW-WE 360
+ P W W+
Sbjct: 701 I-PKWQWQ 707
Score = 57.8 bits (138), Expect = 2e-08
Identities = 85/330 (25%), Positives = 143/330 (43%), Gaps = 48/330 (14%)
Query: 13 KQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQELQRVDKLVDGA 72
+QQLR Q R + +L P+ ++ ++ Q EQ+L+R ++
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER----- 1545
Query: 73 GDFSEFFEWQKKMQAKDR----EEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQ 128
Q++ Q +DR EEQL + EE L+RQ ++ K R+E+
Sbjct: 1546 --------GQQRRQDRDRKFREEEQL----------RQEREEQQLSRQE--RDRKFRLEE 1585
Query: 129 QKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESR 188
Q K+ Q ER+ ED ++L Q EGQ+ + + + + +Q +QE E+
Sbjct: 1586 Q-----KVRRQEQERKFMED--EQQLRRQ--EGQQQLRQERDRKFREDEQLLQEREEQQL 1636
Query: 189 GLLQRRAQAAQEE-QRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRE 247
+R + +EE Q RR E QLR R K + Q+ G E ++ E R+
Sbjct: 1637 HRQERDRKFLEEEPQLRRQEREQQLR-----HDRDRKFREEEQLLQEGEEQQLRRQE-RD 1690
Query: 248 RLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEE-KKAL 306
R +E Q R++E +R + + ++ + QEL+ + R + R E +K L
Sbjct: 1691 RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750
Query: 307 AAAPAAPSQDERVQQLRRRISERAAERSRQ 336
P ++E QQLRR+ +R Q
Sbjct: 1751 EEEQLRPEREE--QQLRRQERDRKFREEEQ 1778
Score = 57.4 bits (137), Expect = 3e-08
Identities = 59/263 (22%), Positives = 125/263 (47%), Gaps = 21/263 (7%)
Query: 7 ERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQV-EQELQRV 65
+++Q ++QL + P + R+ + YR + L + + E +RQ E++ ++
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Query: 66 DKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQR 125
D+L ++++Q ++R+ + E ++ + +L EE R+ ++ ++
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQYR-EEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 126 VEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIE 185
E+ +++ +L+ + E+R R++R R+ E+ ++ Q+ + + + K R+Q ++
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQ-QEEEQLLREEREKRRRQELERQYR 1141
Query: 186 ESRGLLQRRAQAAQE--EQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIV 243
E + Q Q +E E+RRR EL Q R E +L Q E E +
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEE----------ELQQ------EEEQLLR 1185
Query: 244 ELRERLALLKENQRRKEEEKRDQ 266
E +E+ +E Q R+EEE + Q
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQ 1208
Score = 56.6 bits (135), Expect = 5e-08
Identities = 63/302 (20%), Positives = 131/302 (43%), Gaps = 36/302 (11%)
Query: 55 QRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLA 114
Q + EQ+L+R +L ++ Q RE+QL + R + +L E+ +
Sbjct: 376 QLRREQQLRREQQL--------------RREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 115 RQSLMQENK--------------QRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIE 160
Q L +E + QR+++++E+ + + E E RK+ +++ E
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 161 GQKNAKAAQTKLAKGRQQ---TVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALET 217
++ + + + + R+Q Q+ E ++R + +EE+R + L S+ +
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Query: 218 QPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQE 277
Q R+ +L L + LE E L+ ++ ++EEE+R Q ++ ++ + E
Sbjct: 542 QEERREQL--LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 278 LQNMVEQISLCRAAMGRSAALRW---EEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
+ E++ R L+ EE++ + ++ R QQLRR ER +R
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRL 659
Query: 335 RQ 336
++
Sbjct: 660 KR 661
Score = 55.5 bits (132), Expect = 1e-07
Identities = 67/294 (22%), Positives = 129/294 (43%), Gaps = 38/294 (12%)
Query: 56 RQVEQELQRVDKLVDGAGDFSEFFEWQKKM---------QAKDREEQLAASECRRLQGKL 106
+ V+ L+ +D +G DF+EF + K+ QA +E+ A R GK
Sbjct: 52 KTVDLILELLDLDSNGRVDFNEFLLFIFKVAQACYYALGQATGLDEEKRA----RCDGK- 106
Query: 107 SHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAK 166
+SL+Q+ +Q +Q++ + L+ E R + R+E ++ EG++ ++
Sbjct: 107 ---------ESLLQDRRQEEDQRRFEPRDRQLEE-EPGQRRRQKRQEQERELAEGEEQSE 156
Query: 167 AAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLV 226
+ + RQ+ +E + + +R + A+EEQ + C+ + + R+ +L+
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQIS 286
+L + G E + + RER + + + KE KR+ +++ + K QE E+
Sbjct: 217 ELRR---KGREEKQQ--QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE-----EEPQ 266
Query: 287 LCRAAMGRSAALRWEEKKALAAAPAAPSQDE----RVQQLRRRISERAAERSRQ 336
R LR E++ L Q + R QQLRR+ E E+ +
Sbjct: 267 RQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320
Score = 53.5 bits (127), Expect = 4e-07
Identities = 70/276 (25%), Positives = 125/276 (45%), Gaps = 35/276 (12%)
Query: 82 QKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRA 141
+++ K REE+L E QG+ EE Q L ++ ++R ++EQ +L Q
Sbjct: 1355 RQERDRKFREEELRHQE----QGRKFLEE----EQRLRRQERERKFLKEEQ--QLRCQER 1404
Query: 142 ERRLREDRSRK--ELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQ 199
E++LR+DR RK E +Q+ +++ K + + RQ+ ++ +EE + L Q R + +
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Query: 200 EEQ-----------------RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSI 242
EE+ R+ E QLR E + + + + LE E +
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 243 -VELRERLALLKENQRRKEE--EKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALR 299
+ R+R L +E Q R++E ++R Q K + ++L+ E+ L R R R
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSR--QERDRKFR 1582
Query: 300 WEEKKALAAAPAAPSQDERVQQLRRRISERAAERSR 335
EE+K ++ QQLRR+ ++ + R
Sbjct: 1583 LEEQKVRRQEQERKFMEDE-QQLRRQEGQQQLRQER 1617
Score = 50.4 bits (119), Expect = 3e-06
Identities = 82/365 (22%), Positives = 148/365 (40%), Gaps = 59/365 (16%)
Query: 7 ERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQV-------E 59
E VQ ++QL + P + R+ YR + L + +LRE +RQ E
Sbjct: 1144 EEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ-EEEQLLREEQEKRRQERERQYREE 1202
Query: 60 QELQRVDKLV-----DGAGDFSEFFEWQK-------KMQAKDREE----QLAASECRRLQ 103
+ELQR + D D +E +K K+ K RE QL S+ R Q
Sbjct: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262
Query: 104 GKLSHEEAVLARQSLMQENKQRVEQQK-------EQMAKLMLQRAERRLREDRSRKELVE 156
+ + + +Q +E ++R QQ+ EQ+ + + A+RR R+ + K+L+
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322
Query: 157 QVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALE 216
+ E ++ RQ+T ++ EE + L +R Q + ++R R + R E
Sbjct: 1323 EEREEKRR-----------RQETDRKFREEEQLLQEREEQPLRRQERDR-----KFREEE 1366
Query: 217 TQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQ 276
+ +G+ LE E + LKE Q+ + +E+ Q+ Q + K +
Sbjct: 1367 LRHQEQGRKF---------LEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFR 1417
Query: 277 ELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQ 336
E + + + R +R +E++ + ER ++ R E + R+
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR---EEEQLLQERE 1474
Query: 337 AALLH 341
LH
Sbjct: 1475 EQQLH 1479
Score = 48.5 bits (114), Expect = 1e-05
Identities = 70/315 (22%), Positives = 132/315 (41%), Gaps = 37/315 (11%)
Query: 41 KLNTTAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECR 100
+L+ LRE Q + E+ QR + + E + Q++ Q ++RE++L E
Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLP-----EEEEKEQRRRQRREREKELQFLEEE 837
Query: 101 RLQGKLSHEEAVLARQSLMQENKQR---VEQQKEQMAKLMLQRAERRLR---------ED 148
+ + + + +QE+++R EQ+++Q + L+ +R R ++
Sbjct: 838 EQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE 897
Query: 149 RSRKE---LVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRR 205
+ RKE L E+ E Q+ + + + + RQ +E +++ L R + E+RRR
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE----EREKRRR 953
Query: 206 CELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRD 265
E Q R + ++ +L+ E E E E ++ R + E++R
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 266 QIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWE-EKKALAAAPAAPSQDERVQQLRR 324
Q + + K ELQ EQ+ LR E EK+ L ++E +QQ
Sbjct: 1014 QEWERQYRKKDELQQEEEQL------------LREEREKRRLQERERQYREEEELQQEEE 1061
Query: 325 RISERAAERSRQAAL 339
++ E R+ L
Sbjct: 1062 QLLGEERETRRRQEL 1076
Score = 46.6 bits (109), Expect = 5e-05
Identities = 68/300 (22%), Positives = 130/300 (43%), Gaps = 27/300 (9%)
Query: 41 KLNTTAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECR 100
+L + A R+ +Y R +QE QR + E ++K + ++ E Q E
Sbjct: 707 QLESEADARQSKVYSRPRKQEGQRRRQ------------EQEEKRRRRESELQWQEEERA 754
Query: 101 RLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIE 160
Q + + Q +E +R Q+ L QR ER+LR + ++ EQ
Sbjct: 755 HRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR-ERQLRAEERQQR--EQRFL 811
Query: 161 GQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPT 220
++ K + + + R++ +Q EE + + RAQ QEE+ E + R+ E +
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD 871
Query: 221 RKGK--LVDLTQIPGYGLEGEMSIVE-LRERLALLKENQRRKEEEKRDQIIQGKRTKSQE 277
+K + L + + + L + ++ E LR+ LL+E + + E+R++ +R + QE
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK----RRRQEQE 927
Query: 278 LQNMVEQISLCRAAMGRSAALRWE-EKKALAAAPAAPSQDERVQQLRRRISERAAERSRQ 336
Q E+ + LR E EK+ +D+++QQ ++ E+ R+
Sbjct: 928 RQYREEE----QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Score = 45.8 bits (107), Expect = 8e-05
Identities = 38/159 (23%), Positives = 78/159 (49%), Gaps = 14/159 (8%)
Query: 47 ILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKL 106
IL E L + EQ+L+R ++ F +++++ + E+QL + E R K
Sbjct: 1749 ILEEEQLRPEREEQQLRRQER--------DRKFREEEQLRQEREEQQLRSQESDR---KF 1797
Query: 107 SHEEAVLARQSLMQ-ENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNA 165
EE + + Q +QR + + + +L L+ E+RLR++R R+ E+ Q+ +
Sbjct: 1798 REEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKS 1857
Query: 166 KAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRR 204
+ + +L + +Q ++ E R L + + Q+E++R
Sbjct: 1858 RREEQELWQEEEQKRRQ--ERERKLREEHIRRQQKEEQR 1894
Score = 38.1 bits (87), Expect = 0.017
Identities = 43/172 (25%), Positives = 82/172 (47%), Gaps = 23/172 (13%)
Query: 8 RVQGSKQQLRLQFPPR-IRKTPKLTFYRPDNILVKLNTTAILREGA-LYQRQVEQELQRV 65
R + +QQLR Q R R+ +L R + L + RE L Q + EQ+L+
Sbjct: 1756 RPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ 1815
Query: 66 DKLVDGAGDFSEFFEWQKK-MQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQ 124
+ DG + W+++ +Q +++E++L R+ + E A Q + +Q
Sbjct: 1816 QR--DGK------YRWEEEQLQLEEQEQRLRQERDRQYRA-----EEQFATQEKSRREEQ 1862
Query: 125 RVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGR 176
+ Q++EQ + Q ER+LRE+ R++ E+ Q++ + + K +G+
Sbjct: 1863 ELWQEEEQKRR---QERERKLREEHIRRQQKEE----QRHRQVGEIKSQEGK 1907
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 66.2 bits (160), Expect = 6e-11
Identities = 78/319 (24%), Positives = 149/319 (46%), Gaps = 52/319 (16%)
Query: 58 VEQELQRVDKLVDGAGDFSEFFEWQKKMQAKD-REEQLAASECRRLQG-KLSHEEAVLAR 115
VE+E QR++ L ++K +A+ R +++ + RRL+ KL EE R
Sbjct: 535 VEKERQRLENL-------------RRKEEAEQLRRQKVEEDKRRRLEEVKLKREE----R 577
Query: 116 QSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKG 175
+ + ++RVEQ KE+ K + Q+ + ++++ K E++ E + KAA K+ +
Sbjct: 578 LRKVLQARERVEQMKEEKKKQIEQKFAQI--DEKTEKAKEERLAEEKAKKKAAAKKMEEV 635
Query: 176 RQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYG 235
+ QE EE+R L R +EE+RR EL+ + + E + RK +
Sbjct: 636 EARRKQE--EEARRL---RWLQQEEEERRHQELLQKKKEEEQERLRKA-----AEAKRLA 685
Query: 236 LEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRS 295
+ E E +ER + Q R+E+E+R+ Q ++ QE + E++ R R
Sbjct: 686 EQREQERRE-QERREQERREQERREQERRE---QERQLAEQERRREQERLQAERELQERE 741
Query: 296 AALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAA----LLHVS-------- 343
ALR ++++ ++E+ + R++ E +++++AA L+V+
Sbjct: 742 KALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPAC 801
Query: 344 -----APRTARPKPRVSPD 357
P+ R P+++PD
Sbjct: 802 TSYQMTPQGHRAPPKINPD 820
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 66.2 bits (160), Expect = 6e-11
Identities = 70/306 (22%), Positives = 140/306 (45%), Gaps = 48/306 (15%)
Query: 84 KMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQR----VEQQKEQMAKLMLQ 139
+M K++E Q RL+ EEA R+ ++E+K+R V+ ++E+ + +LQ
Sbjct: 527 RMDPKEKERQ-------RLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 579
Query: 140 RAERRLREDRSRKELVEQVIE--GQKNAKAAQTKLA--KGRQQTVQEAIEESRGLLQRRA 195
ER + +K+ +EQ +K KA + +LA K +++ + +EE ++
Sbjct: 580 ARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEE 639
Query: 196 QAA-------QEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRER 248
+A +EE+RR EL+ + + E + RK + + E E +ER
Sbjct: 640 EARRLRWLQQEEEERRHQELLQKKKEEEQERLRKA-----AEAKRLAEQREQERRE-QER 693
Query: 249 LALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAA 308
+ Q R+E+E+R+ Q ++ QE + E++ R R ALR ++++
Sbjct: 694 REQERREQERREQERRE---QERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRE 750
Query: 309 APAAPSQDERVQQLRRRISERAAERSRQAA----LLHVS-------------APRTARPK 351
++E+ + R++ E +++++AA L+V+ P+ R
Sbjct: 751 LEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAP 810
Query: 352 PRVSPD 357
P+++PD
Sbjct: 811 PKINPD 816
Score = 61.2 bits (147), Expect = 2e-09
Identities = 60/229 (26%), Positives = 111/229 (48%), Gaps = 29/229 (12%)
Query: 82 QKKMQAKDREEQLAASECRRLQGKLSH--EEAVLARQSLMQENKQRVEQQKEQMAKLMLQ 139
+K +QA++R EQ+ + ++++ K + E+ A++ + E K + + ++M ++ +
Sbjct: 575 RKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEAR 634
Query: 140 RAE----RRLR------EDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRG 189
R + RRLR E+R +EL+++ E ++ + + +Q QE E+ R
Sbjct: 635 RKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERR 694
Query: 190 LLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERL 249
+RR Q +E++RR Q R L Q R+ + L+ E + E + L
Sbjct: 695 EQERREQERREQERR-----EQERQLAEQERRREQ---------ERLQAERELQEREKAL 740
Query: 250 ALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAAL 298
L KE +R+ EEK+ + Q +R ++LQ EQ + A G S AL
Sbjct: 741 RLQKEQLQRELEEKKKKEEQ-QRLAERQLQE--EQEKKAKEAAGASKAL 786
Score = 47.0 bits (110), Expect = 4e-05
Identities = 49/206 (23%), Positives = 93/206 (45%), Gaps = 16/206 (7%)
Query: 6 RERVQGSKQQLRLQFPPRI----RKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQE 61
RERV+ K++ + Q + KT K R K A E +R+ E+E
Sbjct: 581 RERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 640
Query: 62 LQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQ---LAASECRRLQGKLSHEEAVLARQSL 118
+R+ L E Q+ +Q K EEQ A+E +RL + E R+
Sbjct: 641 ARRLRWLQQE----EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 696
Query: 119 MQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQ 178
+ ++R EQ++ + + Q AE+ R ++ R + ++ E +K + + +L + ++
Sbjct: 697 ERREQERREQERREQER---QLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEE 753
Query: 179 TVQEAIEESRGLLQRRAQAAQEEQRR 204
++ EE + L +R+ Q QE++ +
Sbjct: 754 KKKK--EEQQRLAERQLQEEQEKKAK 777
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 63.2 bits (152), Expect = 5e-10
Identities = 58/283 (20%), Positives = 132/283 (46%), Gaps = 41/283 (14%)
Query: 56 RQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASE--CRRLQGKLSHEEAVL 113
R+ E++++R ++++ W+K+ + + +EE + E R L+ K+ +E +
Sbjct: 312 REQEEKMRRQEEMM-----------WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 360
Query: 114 ARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLA 173
++ QE ++ EQ+K Q + + R E ++RE + E++++ Q+ Q +
Sbjct: 361 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM 420
Query: 174 KGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPG 233
+++ +QE E+ R R+ + +E++++ E ++R E + + +
Sbjct: 421 WEQEEEMQEQEEKMR----RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMG------ 470
Query: 234 YGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMG 293
E E + E ++ +E RR+EE+ R+ Q K+ + QE E+I M
Sbjct: 471 ---EQEGKMCEQEAKMQEQEEKMRRQEEKIRE---QEKKIREQE-----EKIREQEEMMQ 519
Query: 294 RSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQ 336
WE+++ + Q+E++Q+ ++ R E+ R+
Sbjct: 520 EQEEKMWEQEEKMC------EQEEKMQEQEEKM-RRQEEKMRE 555
Score = 56.6 bits (135), Expect = 5e-08
Identities = 50/229 (21%), Positives = 119/229 (51%), Gaps = 18/229 (7%)
Query: 56 RQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLAR 115
R++E+++ +K+ + E ++K++ +++ ++ A R+ + EE + +
Sbjct: 347 RELEEKMHEQEKIREQEEKRQE----EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402
Query: 116 QSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKG 175
+ +MQE ++++ +Q+E+M + Q E + +E++ R++ E++ E +K + + K+ +
Sbjct: 403 EEMMQEQEEKMGEQEEKMWE---QEEEMQEQEEKMRRQ-EEKIREQEKKIREQEEKIREQ 458
Query: 176 RQ--QTVQEAIEESRGLL---QRRAQAAQEEQRRRCELI-SQLRALETQPTRKGKLVDLT 229
+ Q +E + E G + + + Q +E+ RR+ E I Q + + Q + + ++
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 230 QIPGYGL-EGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQE 277
Q + E E + E E++ +E RR+EE+ R+Q + R + QE
Sbjct: 519 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV---RLRQQE 564
Score = 52.4 bits (124), Expect = 9e-07
Identities = 58/296 (19%), Positives = 131/296 (44%), Gaps = 31/296 (10%)
Query: 53 LYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKL-SHEEA 111
L Q+Q++ E + K E K+QA+ E +L ++ + K+ EE
Sbjct: 246 LPQQQLQAEADHLGK---------ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEK 296
Query: 112 VLARQSLMQENKQRVEQQKEQMAK---LMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
+ R+ +QE ++++ +Q+E+M + +M ++ E+ R++ E E++ E ++
Sbjct: 297 IQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 356
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCE---LISQLRALETQPTRKGKL 225
+ + ++ +E I E ++ A+ ++E++ R + + Q ++ Q + G
Sbjct: 357 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG-- 414
Query: 226 VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQI 285
E E + E E + +E RR+EE+ R+Q + R + ++++ E +
Sbjct: 415 -----------EQEEKMWEQEEEMQEQEEKMRRQEEKIREQ-EKKIREQEEKIREQEEMM 462
Query: 286 SLCRAAMGRSAALRWE-EKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
MG E E K Q+E++++ ++I E+ + Q ++
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Score = 47.0 bits (110), Expect = 4e-05
Identities = 51/274 (18%), Positives = 118/274 (43%), Gaps = 25/274 (9%)
Query: 82 QKKMQAK-DREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQR 140
Q+++QA+ D + S +LQ ++ E + R + QE K +++K Q + +Q
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENE-LWNRLNQQQEEKMWRQEEKIQEREEKIQE 306
Query: 141 AERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQE 200
E ++RE + E+++ ++ Q ++ +++ ++E E+ ++ QE
Sbjct: 307 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH---EQEKIREQE 363
Query: 201 EQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE 260
E+R+ E I + + Q + + + ++RE+ ++E + +
Sbjct: 364 EKRQEEEKIREQEKRQEQEAKMWRQEE----------------KIREQEEKIREQEEMMQ 407
Query: 261 EEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQ 320
E++ Q ++ QE + M EQ R + +R +EKK Q+E +Q
Sbjct: 408 EQEEKMGEQEEKMWEQE-EEMQEQEEKMRR---QEEKIREQEKKIREQEEKIREQEEMMQ 463
Query: 321 QLRRRISERAAERSRQAALLHVSAPRTARPKPRV 354
+ ++ E+ + Q A + + R + ++
Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKI 497
Score = 36.2 bits (82), Expect = 0.064
Identities = 24/106 (22%), Positives = 57/106 (53%), Gaps = 8/106 (7%)
Query: 55 QRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKL-SHEEAVL 113
+ Q E ++ +K+ + G + E + KMQ ++ + + + R + K+ EE +
Sbjct: 456 REQEEMMQEQEEKMGEQEG---KMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 512
Query: 114 ARQSLMQENKQRVEQQKEQMA----KLMLQRAERRLREDRSRKELV 155
++ +MQE ++++ +Q+E+M K+ Q + R +E++ R++ V
Sbjct: 513 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558
Score = 35.0 bits (79), Expect = 0.14
Identities = 44/217 (20%), Positives = 92/217 (42%), Gaps = 26/217 (11%)
Query: 142 ERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEE 201
E+ L ++K+ ++ IE + A + L R E ++E LQ + Q + E
Sbjct: 166 EQALSAVATQKKKADRYIEELTKERDALS-LELYRNTITDEELKEKNAKLQEKLQLVESE 224
Query: 202 QRR-------------RCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRER 248
+ R +L+ + L+ + GK + Q L+ ++ EL R
Sbjct: 225 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL---QSVSAKLQAQVEENELWNR 281
Query: 249 LALLKENQRRKEEEK---RDQIIQGKRTKSQE----LQNMVEQISLCRAAMGRSAALRWE 301
L +E + ++EEK R++ IQ + K +E ++ E + M R + WE
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 302 EKKALAAAPAAPSQDERV--QQLRRRISERAAERSRQ 336
+++ + + E++ Q+ +R+ E+ E+ ++
Sbjct: 342 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 378
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 61.2 bits (147), Expect = 2e-09
Identities = 84/340 (24%), Positives = 146/340 (42%), Gaps = 39/340 (11%)
Query: 53 LYQRQVEQ--ELQRVDKLVDGAGDFSEFFEWQKKMQAKDRE--EQLAASECRR-LQGKLS 107
L+Q+ V E+Q+ +K A E ++ + + RE E++ A E RR L+ KL
Sbjct: 157 LHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQ 216
Query: 108 HEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAE-RRLREDRSRKELVEQVIEGQKNAK 166
E + + L + + + +KEQ L+ QR E RL E+R + E Q E + +
Sbjct: 217 AEALLQQMEELKLKEVEATKLKKEQ-ENLLKQRWELERLEEERKQMEAFRQKAELGRFLR 275
Query: 167 AAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQR----RRCELISQL--------RA 214
R Q +QE +E R +LQ + E QR RR ++++ +
Sbjct: 276 HQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQ 335
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLA---LLKENQRRKEEEKRDQIIQGK 271
L+ + R+ +L L + + + RER A L+ E ++++ +++I Q +
Sbjct: 336 LQLERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNR 395
Query: 272 RTKSQEL-------QNMVEQISLCRAAMGRSAALRWEEKKALAAAPA--------APSQD 316
R + + L +N+ E L R S L+ K+ L A A A Q+
Sbjct: 396 RAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAERRLQAWEADQQE 455
Query: 317 ERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSP 356
E ++ RR+ + + +Q A A + RPKP P
Sbjct: 456 EEEEEEARRVEQLSDALLQQEA--ETMAEQGYRPKPYGHP 493
Score = 37.4 bits (85), Expect = 0.029
Identities = 57/264 (21%), Positives = 120/264 (45%), Gaps = 20/264 (7%)
Query: 83 KKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAE 142
K+ Q K EQL ++ KL E L ++ ++ + + E++K+Q A +
Sbjct: 127 KEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKR 186
Query: 143 RRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+R+R+E +E+ ++ ++ + + KL + + + + +EE + L + A ++EQ
Sbjct: 187 YENEYERARREALER-MKAEEERRQLEDKL---QAEALLQQMEELK-LKEVEATKLKKEQ 241
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMS-IVELRERLALLKENQRRKEE 261
+ +L LE + RK Q+ + + E+ + + L + Q+ +EE
Sbjct: 242 ENLLKQRWELERLEEE--RK-------QMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEE 292
Query: 262 EKRD-QIIQGKRTKSQELQNM----VEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQD 316
+ D +I+Q K E Q + EQ+ A M ++ + + ++A A ++
Sbjct: 293 LEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLRE 352
Query: 317 ERVQQLRRRISERAAERSRQAALL 340
E + +R +E A ERS + L+
Sbjct: 353 EAKEMWEKREAEWARERSARDRLM 376
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 61.2 bits (147), Expect = 2e-09
Identities = 84/340 (24%), Positives = 146/340 (42%), Gaps = 39/340 (11%)
Query: 53 LYQRQVEQ--ELQRVDKLVDGAGDFSEFFEWQKKMQAKDRE--EQLAASECRR-LQGKLS 107
L+Q+ V E+Q+ +K A E ++ + + RE E++ A E RR L+ KL
Sbjct: 157 LHQKHVVNSWEMQKEEKKQQEATAEQENKRYENEYERARREALERMKAEEERRQLEDKLQ 216
Query: 108 HEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAE-RRLREDRSRKELVEQVIEGQKNAK 166
E + + L + + + +KEQ L+ QR E RL E+R + E Q E + +
Sbjct: 217 AEALLQQMEELKLKEVEATKLKKEQ-ENLLKQRWELERLEEERKQMEAFRQKAELGRFLR 275
Query: 167 AAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQR----RRCELISQL--------RA 214
R Q +QE +E R +LQ + E QR RR ++++ +
Sbjct: 276 HQYNAQLSRRTQQIQEELEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQ 335
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLA---LLKENQRRKEEEKRDQIIQGK 271
L+ + R+ +L L + + + RER A L+ E ++++ +++I Q +
Sbjct: 336 LQLERAREAELQMLLREEAKEMWEKREAEWARERSARDRLMSEVLTGRQQQIQEKIEQNR 395
Query: 272 RTKSQEL-------QNMVEQISLCRAAMGRSAALRWEEKKALAAAPA--------APSQD 316
R + + L +N+ E L R S L+ K+ L A A A Q+
Sbjct: 396 RAQEESLKHREQLIRNLEEVRELARREKEESEKLKSARKQELEAQVAERRLQAWEADQQE 455
Query: 317 ERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPRVSP 356
E ++ RR+ + + +Q A A + RPKP P
Sbjct: 456 EEEEEEARRVEQLSDALLQQEA--ETMAEQGYRPKPYGHP 493
Score = 37.4 bits (85), Expect = 0.029
Identities = 57/264 (21%), Positives = 120/264 (45%), Gaps = 20/264 (7%)
Query: 83 KKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAE 142
K+ Q K EQL ++ KL E L ++ ++ + + E++K+Q A +
Sbjct: 127 KEEQRKLIAEQLLYEHWKKNNPKLREMELDLHQKHVVNSWEMQKEEKKQQEATAEQENKR 186
Query: 143 RRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+R+R+E +E+ ++ ++ + + KL + + + + +EE + L + A ++EQ
Sbjct: 187 YENEYERARREALER-MKAEEERRQLEDKL---QAEALLQQMEELK-LKEVEATKLKKEQ 241
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMS-IVELRERLALLKENQRRKEE 261
+ +L LE + RK Q+ + + E+ + + L + Q+ +EE
Sbjct: 242 ENLLKQRWELERLEEE--RK-------QMEAFRQKAELGRFLRHQYNAQLSRRTQQIQEE 292
Query: 262 EKRD-QIIQGKRTKSQELQNM----VEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQD 316
+ D +I+Q K E Q + EQ+ A M ++ + + ++A A ++
Sbjct: 293 LEADRRILQALLEKEDESQRLHLARREQVMADVAWMKQAIEEQLQLERAREAELQMLLRE 352
Query: 317 ERVQQLRRRISERAAERSRQAALL 340
E + +R +E A ERS + L+
Sbjct: 353 EAKEMWEKREAEWARERSARDRLM 376
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 60.5 bits (145), Expect = 3e-09
Identities = 83/341 (24%), Positives = 150/341 (43%), Gaps = 50/341 (14%)
Query: 6 RERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQR--------- 56
++R + ++LRLQ R+ + R + V L T E L +
Sbjct: 1531 KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTA 1590
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREE--------QLAASECRRLQGKLSH 108
Q+E+ LQ V + +E Q+ + REE QL A+E RL +L
Sbjct: 1591 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL--RLQA 1648
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE V ++SL Q ++ +++ E+ A+ + E+ +R+ +EL EQ +E Q+
Sbjct: 1649 EE-VAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ----RELAEQELEKQR----- 1698
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC--ELISQLRALETQPTRKGKLV 226
+LA+G T Q+ + + L++ RA+ Q EQ+R+ E +++L+ T+K +
Sbjct: 1699 --QLAEG---TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ-- 1751
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQIS 286
E E + ++R + +L ++ R EEE R + K+ E E
Sbjct: 1752 ----------ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1801
Query: 287 LCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRIS 327
AA R+ A + ++ LA AA + E + L +++
Sbjct: 1802 --EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1840
Score = 59.3 bits (142), Expect = 7e-09
Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 28/248 (11%)
Query: 119 MQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQ 178
+ E +R+E++ E++A+ RL E + E Q+ E AKA + AK QQ
Sbjct: 1337 ISETLRRMEEE-ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1395
Query: 179 TVQEAI---EESRGLLQRRAQAAQEE---QRRRCELISQLRALETQPTRKGKL------- 225
+QE + EE+ Q++ ++ QEE R+ E Q +A + + + +L
Sbjct: 1396 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1455
Query: 226 -----VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
++ T+ G EGE+ + R A ++ Q ++E E+ + +Q + + ++
Sbjct: 1456 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ--- 1512
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
++ L + A R E+++AL A Q E + RR+ + ER+RQ +
Sbjct: 1513 --AEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAE---RRLRQAEVERARQVQVA 1566
Query: 341 HVSAPRTA 348
+A R+A
Sbjct: 1567 LETAQRSA 1574
Score = 49.3 bits (116), Expect = 7e-06
Identities = 78/351 (22%), Positives = 152/351 (43%), Gaps = 64/351 (18%)
Query: 45 TAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFE-----WQKKMQAKDREEQLAASEC 99
T + E L Q+Q E ++ +L + ++ +Q+ ++A+ + + ++E
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2382
Query: 100 RRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAK------------------LMLQRA 141
RL+ +++ AR +E+ QR +Q E++ + L +QR
Sbjct: 2383 ERLKLRVAEMSRAQARA---EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 142 E-----RRLRE-----DRSRKELVEQV----IEGQKNAKAAQTKLAKGRQQTVQEAIEES 187
+ RLRE +R +++L ++ ++ ++ Q +L + Q Q + E
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2499
Query: 188 RGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRE 247
LLQR + E+++ + E + Q + Q R+ + Q+ S+ E R
Sbjct: 2500 DSLLQR--ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2557
Query: 248 RLALLKENQRRKEEEKRDQIIQGKRTK----SQELQNMVEQISLC----RAAMGRSAALR 299
R +E RRK+EE + Q+ Q +R + ++E Q + EQ+ L RAA+ S +
Sbjct: 2558 RQHEAEEGVRRKQEELQ-QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2616
Query: 300 WEEKKALAA---------APAAPSQDER-VQQLRRRISERAAERSRQAALL 340
+ A PAA ++ E LRR++S A+R ++A +L
Sbjct: 2617 ASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVS---AQRLQEAGIL 2664
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 46/273 (16%)
Query: 86 QAKDREEQLAASECRRLQGKL-SHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR 144
QAK + E+ A +R+Q ++ EEA + Q + ++ ++Q ++ + +A +
Sbjct: 1381 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1440
Query: 145 LREDRSRKELVEQ--VIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+RSR + E+ V+ Q A Q A+G Q ++ EE+ ++ QA +E +
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA---QKRQAQEEAE 1497
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-- 260
R R R ++ + RK + VEL R+ E R K+
Sbjct: 1498 RLR-------RQVQDESQRK----------------RQAEVELASRVKAEAEAAREKQRA 1534
Query: 261 ----EEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAA---- 312
EE R Q + +R Q Q+ + RSA + K+A A A
Sbjct: 1535 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1594
Query: 313 PSQDER--VQQLRRRISERA-----AERSRQAA 338
Q+E V QLR RA AER+R+ A
Sbjct: 1595 SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1627
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/327 (23%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 48 LREGALYQRQVEQE---LQRVDK---LVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR 101
L E A QRQ+ +E QR + L + E + + + +E++ RR
Sbjct: 1809 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1868
Query: 102 LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR--LRED--RSRKELVEQ 157
L + + L Q+ ++K +E++ Q+ K ER+ L ED R R+++ E+
Sbjct: 1869 LAEDEAFQRRRLEEQAA--QHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1926
Query: 158 VIEGQKN-----AKAAQTKLAKGR-----QQTVQEAIEESRGLLQRRAQAAQEEQRRR-- 205
++ + + A A+ +L GR + T++ + ++R AA+EE+RRR
Sbjct: 1927 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1986
Query: 206 CELISQLRALETQPT--RKGKLVDLTQIPGYGLEG----EMSIVELRERLALLKENQRRK 259
E + + A E + RK L ++ ++ E E + E +L L +E +++
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 260 EEEKRDQIIQGKRTKSQELQNMVEQISLC------RAAMGRSAALRWEEKKALAAAPAAP 313
+ + + K QELQ ++Q A R AA EE + A AA
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 314 S--QDERVQQLRRRISERAAERSRQAA 338
S Q E ++L++ E+A R++ A
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQA 2133
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/290 (21%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQK---KMQAKDREEQLAASECRRLQGKLSHEEAVL 113
QVEQEL + ++ + + K +A + Q + E ++ EE
Sbjct: 2183 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2242
Query: 114 ARQSLMQENKQRVEQQKEQMAKLMLQRAE--RRLREDRSRKELVEQ--------VIEGQK 163
+ + EN+ + + K+ + + + AE +++ E+ +R + Q E
Sbjct: 2243 LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA 2302
Query: 164 NAKAAQTKLAKGRQQTVQEA--IEESRGLLQRRAQAAQEEQRR---RCELISQLRALETQ 218
+A K+ K + Q VQEA ++ LLQ++ + AQE+ RR E ++Q A ETQ
Sbjct: 2303 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2362
Query: 219 PTRKGKLVDLTQIPGYGLEGE---MSIVELRERLALLKENQR--RKEEEKRDQIIQGKRT 273
++ + + E E + + E+ A +E+ + RK+ E+ + +
Sbjct: 2363 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2422
Query: 274 KSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLR 323
+QE +V+ + + R A E L Q+ ++ QL+
Sbjct: 2423 ATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2472
Score = 43.1 bits (100), Expect = 5e-04
Identities = 73/342 (21%), Positives = 140/342 (40%), Gaps = 61/342 (17%)
Query: 46 AILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR---- 101
A + A + ++E EL R+ + E Q +++A R+ QLAA E RR
Sbjct: 1932 ASFEKAAAGKAELELELGRIRSNAEDTLRSKE----QAELEAA-RQRQLAAEEERRRREA 1986
Query: 102 ---LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQV 158
+Q L+ EE ++ E +R++ + E+ +L + + R+ + +E ++
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 159 IEGQKNAKA-AQTKLAKGRQQTVQE---AIEESRGLLQRRAQAAQEEQRRRCELISQLRA 214
++ ++ A A A + + QQT+Q+ +++ RG + +AA+E + R + +
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTK 274
Q VE ERL ++ E++ Q +
Sbjct: 2107 SRRQ------------------------VEEAERL--------KQSAEEQAQARAQAQAA 2134
Query: 275 SQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
+++L+ EQ R A AALR ++ AA ++ E+ ++ + + A+
Sbjct: 2135 AEKLRKEAEQ-EAARRAQAEQAALRQKQ--------AADAEMEKHKKFAEQTLRQKAQVE 2185
Query: 335 RQAALLHVSAPRTARPKPRVSPDWWEEPGRLKAGAGWGWRAR 376
++ L + T K + EE RLKA A R R
Sbjct: 2186 QELTTLRLQLEETDHQKNLLD----EELQRLKAEATEAARQR 2223
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 60.5 bits (145), Expect = 3e-09
Identities = 83/341 (24%), Positives = 150/341 (43%), Gaps = 50/341 (14%)
Query: 6 RERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQR--------- 56
++R + ++LRLQ R+ + R + V L T E L +
Sbjct: 1535 KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTA 1594
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREE--------QLAASECRRLQGKLSH 108
Q+E+ LQ V + +E Q+ + REE QL A+E RL +L
Sbjct: 1595 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL--RLQA 1652
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE V ++SL Q ++ +++ E+ A+ + E+ +R+ +EL EQ +E Q+
Sbjct: 1653 EE-VAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ----RELAEQELEKQR----- 1702
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC--ELISQLRALETQPTRKGKLV 226
+LA+G T Q+ + + L++ RA+ Q EQ+R+ E +++L+ T+K +
Sbjct: 1703 --QLAEG---TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ-- 1755
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQIS 286
E E + ++R + +L ++ R EEE R + K+ E E
Sbjct: 1756 ----------ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1805
Query: 287 LCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRIS 327
AA R+ A + ++ LA AA + E + L +++
Sbjct: 1806 --EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1844
Score = 59.3 bits (142), Expect = 7e-09
Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 28/248 (11%)
Query: 119 MQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQ 178
+ E +R+E++ E++A+ RL E + E Q+ E AKA + AK QQ
Sbjct: 1341 ISETLRRMEEE-ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1399
Query: 179 TVQEAI---EESRGLLQRRAQAAQEE---QRRRCELISQLRALETQPTRKGKL------- 225
+QE + EE+ Q++ ++ QEE R+ E Q +A + + + +L
Sbjct: 1400 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1459
Query: 226 -----VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
++ T+ G EGE+ + R A ++ Q ++E E+ + +Q + + ++
Sbjct: 1460 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ--- 1516
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
++ L + A R E+++AL A Q E + RR+ + ER+RQ +
Sbjct: 1517 --AEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAE---RRLRQAEVERARQVQVA 1570
Query: 341 HVSAPRTA 348
+A R+A
Sbjct: 1571 LETAQRSA 1578
Score = 49.3 bits (116), Expect = 7e-06
Identities = 78/351 (22%), Positives = 152/351 (43%), Gaps = 64/351 (18%)
Query: 45 TAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFE-----WQKKMQAKDREEQLAASEC 99
T + E L Q+Q E ++ +L + ++ +Q+ ++A+ + + ++E
Sbjct: 2327 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2386
Query: 100 RRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAK------------------LMLQRA 141
RL+ +++ AR +E+ QR +Q E++ + L +QR
Sbjct: 2387 ERLKLRVAEMSRAQARA---EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2443
Query: 142 E-----RRLRE-----DRSRKELVEQV----IEGQKNAKAAQTKLAKGRQQTVQEAIEES 187
+ RLRE +R +++L ++ ++ ++ Q +L + Q Q + E
Sbjct: 2444 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2503
Query: 188 RGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRE 247
LLQR + E+++ + E + Q + Q R+ + Q+ S+ E R
Sbjct: 2504 DSLLQR--ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2561
Query: 248 RLALLKENQRRKEEEKRDQIIQGKRTK----SQELQNMVEQISLC----RAAMGRSAALR 299
R +E RRK+EE + Q+ Q +R + ++E Q + EQ+ L RAA+ S +
Sbjct: 2562 RQHEAEEGVRRKQEELQ-QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2620
Query: 300 WEEKKALAA---------APAAPSQDER-VQQLRRRISERAAERSRQAALL 340
+ A PAA ++ E LRR++S A+R ++A +L
Sbjct: 2621 ASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVS---AQRLQEAGIL 2668
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 46/273 (16%)
Query: 86 QAKDREEQLAASECRRLQGKL-SHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR 144
QAK + E+ A +R+Q ++ EEA + Q + ++ ++Q ++ + +A +
Sbjct: 1385 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1444
Query: 145 LREDRSRKELVEQ--VIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+RSR + E+ V+ Q A Q A+G Q ++ EE+ ++ QA +E +
Sbjct: 1445 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA---QKRQAQEEAE 1501
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-- 260
R R R ++ + RK + VEL R+ E R K+
Sbjct: 1502 RLR-------RQVQDESQRK----------------RQAEVELASRVKAEAEAAREKQRA 1538
Query: 261 ----EEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAA---- 312
EE R Q + +R Q Q+ + RSA + K+A A A
Sbjct: 1539 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1598
Query: 313 PSQDER--VQQLRRRISERA-----AERSRQAA 338
Q+E V QLR RA AER+R+ A
Sbjct: 1599 SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1631
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/327 (23%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 48 LREGALYQRQVEQE---LQRVDK---LVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR 101
L E A QRQ+ +E QR + L + E + + + +E++ RR
Sbjct: 1813 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1872
Query: 102 LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR--LRED--RSRKELVEQ 157
L + + L Q+ ++K +E++ Q+ K ER+ L ED R R+++ E+
Sbjct: 1873 LAEDEAFQRRRLEEQAA--QHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1930
Query: 158 VIEGQKN-----AKAAQTKLAKGR-----QQTVQEAIEESRGLLQRRAQAAQEEQRRR-- 205
++ + + A A+ +L GR + T++ + ++R AA+EE+RRR
Sbjct: 1931 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1990
Query: 206 CELISQLRALETQPT--RKGKLVDLTQIPGYGLEG----EMSIVELRERLALLKENQRRK 259
E + + A E + RK L ++ ++ E E + E +L L +E +++
Sbjct: 1991 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2050
Query: 260 EEEKRDQIIQGKRTKSQELQNMVEQISLC------RAAMGRSAALRWEEKKALAAAPAAP 313
+ + + K QELQ ++Q A R AA EE + A AA
Sbjct: 2051 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2110
Query: 314 S--QDERVQQLRRRISERAAERSRQAA 338
S Q E ++L++ E+A R++ A
Sbjct: 2111 SRRQVEEAERLKQSAEEQAQARAQAQA 2137
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/290 (21%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQK---KMQAKDREEQLAASECRRLQGKLSHEEAVL 113
QVEQEL + ++ + + K +A + Q + E ++ EE
Sbjct: 2187 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2246
Query: 114 ARQSLMQENKQRVEQQKEQMAKLMLQRAE--RRLREDRSRKELVEQ--------VIEGQK 163
+ + EN+ + + K+ + + + AE +++ E+ +R + Q E
Sbjct: 2247 LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA 2306
Query: 164 NAKAAQTKLAKGRQQTVQEA--IEESRGLLQRRAQAAQEEQRR---RCELISQLRALETQ 218
+A K+ K + Q VQEA ++ LLQ++ + AQE+ RR E ++Q A ETQ
Sbjct: 2307 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2366
Query: 219 PTRKGKLVDLTQIPGYGLEGE---MSIVELRERLALLKENQR--RKEEEKRDQIIQGKRT 273
++ + + E E + + E+ A +E+ + RK+ E+ + +
Sbjct: 2367 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2426
Query: 274 KSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLR 323
+QE +V+ + + R A E L Q+ ++ QL+
Sbjct: 2427 ATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2476
Score = 43.1 bits (100), Expect = 5e-04
Identities = 73/342 (21%), Positives = 140/342 (40%), Gaps = 61/342 (17%)
Query: 46 AILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR---- 101
A + A + ++E EL R+ + E Q +++A R+ QLAA E RR
Sbjct: 1936 ASFEKAAAGKAELELELGRIRSNAEDTLRSKE----QAELEAA-RQRQLAAEEERRRREA 1990
Query: 102 ---LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQV 158
+Q L+ EE ++ E +R++ + E+ +L + + R+ + +E ++
Sbjct: 1991 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2050
Query: 159 IEGQKNAKA-AQTKLAKGRQQTVQE---AIEESRGLLQRRAQAAQEEQRRRCELISQLRA 214
++ ++ A A A + + QQT+Q+ +++ RG + +AA+E + R + +
Sbjct: 2051 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2110
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTK 274
Q VE ERL ++ E++ Q +
Sbjct: 2111 SRRQ------------------------VEEAERL--------KQSAEEQAQARAQAQAA 2138
Query: 275 SQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
+++L+ EQ R A AALR ++ AA ++ E+ ++ + + A+
Sbjct: 2139 AEKLRKEAEQ-EAARRAQAEQAALRQKQ--------AADAEMEKHKKFAEQTLRQKAQVE 2189
Query: 335 RQAALLHVSAPRTARPKPRVSPDWWEEPGRLKAGAGWGWRAR 376
++ L + T K + EE RLKA A R R
Sbjct: 2190 QELTTLRLQLEETDHQKNLLD----EELQRLKAEATEAARQR 2227
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 60.5 bits (145), Expect = 3e-09
Identities = 83/341 (24%), Positives = 150/341 (43%), Gaps = 50/341 (14%)
Query: 6 RERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQR--------- 56
++R + ++LRLQ R+ + R + V L T E L +
Sbjct: 1531 KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTA 1590
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREE--------QLAASECRRLQGKLSH 108
Q+E+ LQ V + +E Q+ + REE QL A+E RL +L
Sbjct: 1591 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL--RLQA 1648
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE V ++SL Q ++ +++ E+ A+ + E+ +R+ +EL EQ +E Q+
Sbjct: 1649 EE-VAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ----RELAEQELEKQR----- 1698
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC--ELISQLRALETQPTRKGKLV 226
+LA+G T Q+ + + L++ RA+ Q EQ+R+ E +++L+ T+K +
Sbjct: 1699 --QLAEG---TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ-- 1751
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQIS 286
E E + ++R + +L ++ R EEE R + K+ E E
Sbjct: 1752 ----------ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1801
Query: 287 LCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRIS 327
AA R+ A + ++ LA AA + E + L +++
Sbjct: 1802 --EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1840
Score = 59.3 bits (142), Expect = 7e-09
Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 28/248 (11%)
Query: 119 MQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQ 178
+ E +R+E++ E++A+ RL E + E Q+ E AKA + AK QQ
Sbjct: 1337 ISETLRRMEEE-ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1395
Query: 179 TVQEAI---EESRGLLQRRAQAAQEE---QRRRCELISQLRALETQPTRKGKL------- 225
+QE + EE+ Q++ ++ QEE R+ E Q +A + + + +L
Sbjct: 1396 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1455
Query: 226 -----VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
++ T+ G EGE+ + R A ++ Q ++E E+ + +Q + + ++
Sbjct: 1456 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ--- 1512
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
++ L + A R E+++AL A Q E + RR+ + ER+RQ +
Sbjct: 1513 --AEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAE---RRLRQAEVERARQVQVA 1566
Query: 341 HVSAPRTA 348
+A R+A
Sbjct: 1567 LETAQRSA 1574
Score = 49.3 bits (116), Expect = 7e-06
Identities = 78/351 (22%), Positives = 152/351 (43%), Gaps = 64/351 (18%)
Query: 45 TAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFE-----WQKKMQAKDREEQLAASEC 99
T + E L Q+Q E ++ +L + ++ +Q+ ++A+ + + ++E
Sbjct: 2323 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2382
Query: 100 RRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAK------------------LMLQRA 141
RL+ +++ AR +E+ QR +Q E++ + L +QR
Sbjct: 2383 ERLKLRVAEMSRAQARA---EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2439
Query: 142 E-----RRLRE-----DRSRKELVEQV----IEGQKNAKAAQTKLAKGRQQTVQEAIEES 187
+ RLRE +R +++L ++ ++ ++ Q +L + Q Q + E
Sbjct: 2440 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2499
Query: 188 RGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRE 247
LLQR + E+++ + E + Q + Q R+ + Q+ S+ E R
Sbjct: 2500 DSLLQR--ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2557
Query: 248 RLALLKENQRRKEEEKRDQIIQGKRTK----SQELQNMVEQISLC----RAAMGRSAALR 299
R +E RRK+EE + Q+ Q +R + ++E Q + EQ+ L RAA+ S +
Sbjct: 2558 RQHEAEEGVRRKQEELQ-QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2616
Query: 300 WEEKKALAA---------APAAPSQDER-VQQLRRRISERAAERSRQAALL 340
+ A PAA ++ E LRR++S A+R ++A +L
Sbjct: 2617 ASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVS---AQRLQEAGIL 2664
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 46/273 (16%)
Query: 86 QAKDREEQLAASECRRLQGKL-SHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR 144
QAK + E+ A +R+Q ++ EEA + Q + ++ ++Q ++ + +A +
Sbjct: 1381 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1440
Query: 145 LREDRSRKELVEQ--VIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+RSR + E+ V+ Q A Q A+G Q ++ EE+ ++ QA +E +
Sbjct: 1441 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA---QKRQAQEEAE 1497
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-- 260
R R R ++ + RK + VEL R+ E R K+
Sbjct: 1498 RLR-------RQVQDESQRK----------------RQAEVELASRVKAEAEAAREKQRA 1534
Query: 261 ----EEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAA---- 312
EE R Q + +R Q Q+ + RSA + K+A A A
Sbjct: 1535 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1594
Query: 313 PSQDER--VQQLRRRISERA-----AERSRQAA 338
Q+E V QLR RA AER+R+ A
Sbjct: 1595 SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1627
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/327 (23%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 48 LREGALYQRQVEQE---LQRVDK---LVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR 101
L E A QRQ+ +E QR + L + E + + + +E++ RR
Sbjct: 1809 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1868
Query: 102 LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR--LRED--RSRKELVEQ 157
L + + L Q+ ++K +E++ Q+ K ER+ L ED R R+++ E+
Sbjct: 1869 LAEDEAFQRRRLEEQAA--QHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1926
Query: 158 VIEGQKN-----AKAAQTKLAKGR-----QQTVQEAIEESRGLLQRRAQAAQEEQRRR-- 205
++ + + A A+ +L GR + T++ + ++R AA+EE+RRR
Sbjct: 1927 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1986
Query: 206 CELISQLRALETQPT--RKGKLVDLTQIPGYGLEG----EMSIVELRERLALLKENQRRK 259
E + + A E + RK L ++ ++ E E + E +L L +E +++
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 260 EEEKRDQIIQGKRTKSQELQNMVEQISLC------RAAMGRSAALRWEEKKALAAAPAAP 313
+ + + K QELQ ++Q A R AA EE + A AA
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 314 S--QDERVQQLRRRISERAAERSRQAA 338
S Q E ++L++ E+A R++ A
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQA 2133
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/290 (21%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQK---KMQAKDREEQLAASECRRLQGKLSHEEAVL 113
QVEQEL + ++ + + K +A + Q + E ++ EE
Sbjct: 2183 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2242
Query: 114 ARQSLMQENKQRVEQQKEQMAKLMLQRAE--RRLREDRSRKELVEQ--------VIEGQK 163
+ + EN+ + + K+ + + + AE +++ E+ +R + Q E
Sbjct: 2243 LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA 2302
Query: 164 NAKAAQTKLAKGRQQTVQEA--IEESRGLLQRRAQAAQEEQRR---RCELISQLRALETQ 218
+A K+ K + Q VQEA ++ LLQ++ + AQE+ RR E ++Q A ETQ
Sbjct: 2303 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2362
Query: 219 PTRKGKLVDLTQIPGYGLEGE---MSIVELRERLALLKENQR--RKEEEKRDQIIQGKRT 273
++ + + E E + + E+ A +E+ + RK+ E+ + +
Sbjct: 2363 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2422
Query: 274 KSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLR 323
+QE +V+ + + R A E L Q+ ++ QL+
Sbjct: 2423 ATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2472
Score = 43.1 bits (100), Expect = 5e-04
Identities = 73/342 (21%), Positives = 140/342 (40%), Gaps = 61/342 (17%)
Query: 46 AILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR---- 101
A + A + ++E EL R+ + E Q +++A R+ QLAA E RR
Sbjct: 1932 ASFEKAAAGKAELELELGRIRSNAEDTLRSKE----QAELEAA-RQRQLAAEEERRRREA 1986
Query: 102 ---LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQV 158
+Q L+ EE ++ E +R++ + E+ +L + + R+ + +E ++
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 159 IEGQKNAKA-AQTKLAKGRQQTVQE---AIEESRGLLQRRAQAAQEEQRRRCELISQLRA 214
++ ++ A A A + + QQT+Q+ +++ RG + +AA+E + R + +
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTK 274
Q VE ERL ++ E++ Q +
Sbjct: 2107 SRRQ------------------------VEEAERL--------KQSAEEQAQARAQAQAA 2134
Query: 275 SQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
+++L+ EQ R A AALR ++ AA ++ E+ ++ + + A+
Sbjct: 2135 AEKLRKEAEQ-EAARRAQAEQAALRQKQ--------AADAEMEKHKKFAEQTLRQKAQVE 2185
Query: 335 RQAALLHVSAPRTARPKPRVSPDWWEEPGRLKAGAGWGWRAR 376
++ L + T K + EE RLKA A R R
Sbjct: 2186 QELTTLRLQLEETDHQKNLLD----EELQRLKAEATEAARQR 2223
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 60.5 bits (145), Expect = 3e-09
Identities = 83/341 (24%), Positives = 150/341 (43%), Gaps = 50/341 (14%)
Query: 6 RERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQR--------- 56
++R + ++LRLQ R+ + R + V L T E L +
Sbjct: 1499 KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTA 1558
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREE--------QLAASECRRLQGKLSH 108
Q+E+ LQ V + +E Q+ + REE QL A+E RL +L
Sbjct: 1559 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL--RLQA 1616
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE V ++SL Q ++ +++ E+ A+ + E+ +R+ +EL EQ +E Q+
Sbjct: 1617 EE-VAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ----RELAEQELEKQR----- 1666
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC--ELISQLRALETQPTRKGKLV 226
+LA+G T Q+ + + L++ RA+ Q EQ+R+ E +++L+ T+K +
Sbjct: 1667 --QLAEG---TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ-- 1719
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQIS 286
E E + ++R + +L ++ R EEE R + K+ E E
Sbjct: 1720 ----------ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1769
Query: 287 LCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRIS 327
AA R+ A + ++ LA AA + E + L +++
Sbjct: 1770 --EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1808
Score = 59.3 bits (142), Expect = 7e-09
Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 28/248 (11%)
Query: 119 MQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQ 178
+ E +R+E++ E++A+ RL E + E Q+ E AKA + AK QQ
Sbjct: 1305 ISETLRRMEEE-ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1363
Query: 179 TVQEAI---EESRGLLQRRAQAAQEE---QRRRCELISQLRALETQPTRKGKL------- 225
+QE + EE+ Q++ ++ QEE R+ E Q +A + + + +L
Sbjct: 1364 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1423
Query: 226 -----VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
++ T+ G EGE+ + R A ++ Q ++E E+ + +Q + + ++
Sbjct: 1424 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ--- 1480
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
++ L + A R E+++AL A Q E + RR+ + ER+RQ +
Sbjct: 1481 --AEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAE---RRLRQAEVERARQVQVA 1534
Query: 341 HVSAPRTA 348
+A R+A
Sbjct: 1535 LETAQRSA 1542
Score = 49.3 bits (116), Expect = 7e-06
Identities = 78/351 (22%), Positives = 152/351 (43%), Gaps = 64/351 (18%)
Query: 45 TAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFE-----WQKKMQAKDREEQLAASEC 99
T + E L Q+Q E ++ +L + ++ +Q+ ++A+ + + ++E
Sbjct: 2291 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2350
Query: 100 RRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAK------------------LMLQRA 141
RL+ +++ AR +E+ QR +Q E++ + L +QR
Sbjct: 2351 ERLKLRVAEMSRAQARA---EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2407
Query: 142 E-----RRLRE-----DRSRKELVEQV----IEGQKNAKAAQTKLAKGRQQTVQEAIEES 187
+ RLRE +R +++L ++ ++ ++ Q +L + Q Q + E
Sbjct: 2408 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2467
Query: 188 RGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRE 247
LLQR + E+++ + E + Q + Q R+ + Q+ S+ E R
Sbjct: 2468 DSLLQR--ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2525
Query: 248 RLALLKENQRRKEEEKRDQIIQGKRTK----SQELQNMVEQISLC----RAAMGRSAALR 299
R +E RRK+EE + Q+ Q +R + ++E Q + EQ+ L RAA+ S +
Sbjct: 2526 RQHEAEEGVRRKQEELQ-QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2584
Query: 300 WEEKKALAA---------APAAPSQDER-VQQLRRRISERAAERSRQAALL 340
+ A PAA ++ E LRR++S A+R ++A +L
Sbjct: 2585 ASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVS---AQRLQEAGIL 2632
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 46/273 (16%)
Query: 86 QAKDREEQLAASECRRLQGKL-SHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR 144
QAK + E+ A +R+Q ++ EEA + Q + ++ ++Q ++ + +A +
Sbjct: 1349 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1408
Query: 145 LREDRSRKELVEQ--VIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+RSR + E+ V+ Q A Q A+G Q ++ EE+ ++ QA +E +
Sbjct: 1409 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA---QKRQAQEEAE 1465
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-- 260
R R R ++ + RK + VEL R+ E R K+
Sbjct: 1466 RLR-------RQVQDESQRK----------------RQAEVELASRVKAEAEAAREKQRA 1502
Query: 261 ----EEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAA---- 312
EE R Q + +R Q Q+ + RSA + K+A A A
Sbjct: 1503 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1562
Query: 313 PSQDER--VQQLRRRISERA-----AERSRQAA 338
Q+E V QLR RA AER+R+ A
Sbjct: 1563 SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1595
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/327 (23%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 48 LREGALYQRQVEQE---LQRVDK---LVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR 101
L E A QRQ+ +E QR + L + E + + + +E++ RR
Sbjct: 1777 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1836
Query: 102 LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR--LRED--RSRKELVEQ 157
L + + L Q+ ++K +E++ Q+ K ER+ L ED R R+++ E+
Sbjct: 1837 LAEDEAFQRRRLEEQAA--QHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1894
Query: 158 VIEGQKN-----AKAAQTKLAKGR-----QQTVQEAIEESRGLLQRRAQAAQEEQRRR-- 205
++ + + A A+ +L GR + T++ + ++R AA+EE+RRR
Sbjct: 1895 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1954
Query: 206 CELISQLRALETQPT--RKGKLVDLTQIPGYGLEG----EMSIVELRERLALLKENQRRK 259
E + + A E + RK L ++ ++ E E + E +L L +E +++
Sbjct: 1955 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2014
Query: 260 EEEKRDQIIQGKRTKSQELQNMVEQISLC------RAAMGRSAALRWEEKKALAAAPAAP 313
+ + + K QELQ ++Q A R AA EE + A AA
Sbjct: 2015 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2074
Query: 314 S--QDERVQQLRRRISERAAERSRQAA 338
S Q E ++L++ E+A R++ A
Sbjct: 2075 SRRQVEEAERLKQSAEEQAQARAQAQA 2101
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/290 (21%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQK---KMQAKDREEQLAASECRRLQGKLSHEEAVL 113
QVEQEL + ++ + + K +A + Q + E ++ EE
Sbjct: 2151 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2210
Query: 114 ARQSLMQENKQRVEQQKEQMAKLMLQRAE--RRLREDRSRKELVEQ--------VIEGQK 163
+ + EN+ + + K+ + + + AE +++ E+ +R + Q E
Sbjct: 2211 LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA 2270
Query: 164 NAKAAQTKLAKGRQQTVQEA--IEESRGLLQRRAQAAQEEQRR---RCELISQLRALETQ 218
+A K+ K + Q VQEA ++ LLQ++ + AQE+ RR E ++Q A ETQ
Sbjct: 2271 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2330
Query: 219 PTRKGKLVDLTQIPGYGLEGE---MSIVELRERLALLKENQR--RKEEEKRDQIIQGKRT 273
++ + + E E + + E+ A +E+ + RK+ E+ + +
Sbjct: 2331 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2390
Query: 274 KSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLR 323
+QE +V+ + + R A E L Q+ ++ QL+
Sbjct: 2391 ATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2440
Score = 43.1 bits (100), Expect = 5e-04
Identities = 73/342 (21%), Positives = 140/342 (40%), Gaps = 61/342 (17%)
Query: 46 AILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR---- 101
A + A + ++E EL R+ + E Q +++A R+ QLAA E RR
Sbjct: 1900 ASFEKAAAGKAELELELGRIRSNAEDTLRSKE----QAELEAA-RQRQLAAEEERRRREA 1954
Query: 102 ---LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQV 158
+Q L+ EE ++ E +R++ + E+ +L + + R+ + +E ++
Sbjct: 1955 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2014
Query: 159 IEGQKNAKA-AQTKLAKGRQQTVQE---AIEESRGLLQRRAQAAQEEQRRRCELISQLRA 214
++ ++ A A A + + QQT+Q+ +++ RG + +AA+E + R + +
Sbjct: 2015 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2074
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTK 274
Q VE ERL ++ E++ Q +
Sbjct: 2075 SRRQ------------------------VEEAERL--------KQSAEEQAQARAQAQAA 2102
Query: 275 SQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
+++L+ EQ R A AALR ++ AA ++ E+ ++ + + A+
Sbjct: 2103 AEKLRKEAEQ-EAARRAQAEQAALRQKQ--------AADAEMEKHKKFAEQTLRQKAQVE 2153
Query: 335 RQAALLHVSAPRTARPKPRVSPDWWEEPGRLKAGAGWGWRAR 376
++ L + T K + EE RLKA A R R
Sbjct: 2154 QELTTLRLQLEETDHQKNLLD----EELQRLKAEATEAARQR 2191
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 60.5 bits (145), Expect = 3e-09
Identities = 83/341 (24%), Positives = 150/341 (43%), Gaps = 50/341 (14%)
Query: 6 RERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQR--------- 56
++R + ++LRLQ R+ + R + V L T E L +
Sbjct: 1668 KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTA 1727
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREE--------QLAASECRRLQGKLSH 108
Q+E+ LQ V + +E Q+ + REE QL A+E RL +L
Sbjct: 1728 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL--RLQA 1785
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE V ++SL Q ++ +++ E+ A+ + E+ +R+ +EL EQ +E Q+
Sbjct: 1786 EE-VAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ----RELAEQELEKQR----- 1835
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC--ELISQLRALETQPTRKGKLV 226
+LA+G T Q+ + + L++ RA+ Q EQ+R+ E +++L+ T+K +
Sbjct: 1836 --QLAEG---TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ-- 1888
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQIS 286
E E + ++R + +L ++ R EEE R + K+ E E
Sbjct: 1889 ----------ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1938
Query: 287 LCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRIS 327
AA R+ A + ++ LA AA + E + L +++
Sbjct: 1939 --EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1977
Score = 59.3 bits (142), Expect = 7e-09
Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 28/248 (11%)
Query: 119 MQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQ 178
+ E +R+E++ E++A+ RL E + E Q+ E AKA + AK QQ
Sbjct: 1474 ISETLRRMEEE-ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1532
Query: 179 TVQEAI---EESRGLLQRRAQAAQEE---QRRRCELISQLRALETQPTRKGKL------- 225
+QE + EE+ Q++ ++ QEE R+ E Q +A + + + +L
Sbjct: 1533 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1592
Query: 226 -----VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
++ T+ G EGE+ + R A ++ Q ++E E+ + +Q + + ++
Sbjct: 1593 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ--- 1649
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
++ L + A R E+++AL A Q E + RR+ + ER+RQ +
Sbjct: 1650 --AEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAE---RRLRQAEVERARQVQVA 1703
Query: 341 HVSAPRTA 348
+A R+A
Sbjct: 1704 LETAQRSA 1711
Score = 49.3 bits (116), Expect = 7e-06
Identities = 78/351 (22%), Positives = 152/351 (43%), Gaps = 64/351 (18%)
Query: 45 TAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFE-----WQKKMQAKDREEQLAASEC 99
T + E L Q+Q E ++ +L + ++ +Q+ ++A+ + + ++E
Sbjct: 2460 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2519
Query: 100 RRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAK------------------LMLQRA 141
RL+ +++ AR +E+ QR +Q E++ + L +QR
Sbjct: 2520 ERLKLRVAEMSRAQARA---EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2576
Query: 142 E-----RRLRE-----DRSRKELVEQV----IEGQKNAKAAQTKLAKGRQQTVQEAIEES 187
+ RLRE +R +++L ++ ++ ++ Q +L + Q Q + E
Sbjct: 2577 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2636
Query: 188 RGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRE 247
LLQR + E+++ + E + Q + Q R+ + Q+ S+ E R
Sbjct: 2637 DSLLQR--ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2694
Query: 248 RLALLKENQRRKEEEKRDQIIQGKRTK----SQELQNMVEQISLC----RAAMGRSAALR 299
R +E RRK+EE + Q+ Q +R + ++E Q + EQ+ L RAA+ S +
Sbjct: 2695 RQHEAEEGVRRKQEELQ-QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2753
Query: 300 WEEKKALAA---------APAAPSQDER-VQQLRRRISERAAERSRQAALL 340
+ A PAA ++ E LRR++S A+R ++A +L
Sbjct: 2754 ASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVS---AQRLQEAGIL 2801
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 46/273 (16%)
Query: 86 QAKDREEQLAASECRRLQGKL-SHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR 144
QAK + E+ A +R+Q ++ EEA + Q + ++ ++Q ++ + +A +
Sbjct: 1518 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1577
Query: 145 LREDRSRKELVEQ--VIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+RSR + E+ V+ Q A Q A+G Q ++ EE+ ++ QA +E +
Sbjct: 1578 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA---QKRQAQEEAE 1634
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-- 260
R R R ++ + RK + VEL R+ E R K+
Sbjct: 1635 RLR-------RQVQDESQRK----------------RQAEVELASRVKAEAEAAREKQRA 1671
Query: 261 ----EEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAA---- 312
EE R Q + +R Q Q+ + RSA + K+A A A
Sbjct: 1672 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1731
Query: 313 PSQDER--VQQLRRRISERA-----AERSRQAA 338
Q+E V QLR RA AER+R+ A
Sbjct: 1732 SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1764
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/327 (23%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 48 LREGALYQRQVEQE---LQRVDK---LVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR 101
L E A QRQ+ +E QR + L + E + + + +E++ RR
Sbjct: 1946 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 2005
Query: 102 LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR--LRED--RSRKELVEQ 157
L + + L Q+ ++K +E++ Q+ K ER+ L ED R R+++ E+
Sbjct: 2006 LAEDEAFQRRRLEEQAA--QHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 2063
Query: 158 VIEGQKN-----AKAAQTKLAKGR-----QQTVQEAIEESRGLLQRRAQAAQEEQRRR-- 205
++ + + A A+ +L GR + T++ + ++R AA+EE+RRR
Sbjct: 2064 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 2123
Query: 206 CELISQLRALETQPT--RKGKLVDLTQIPGYGLEG----EMSIVELRERLALLKENQRRK 259
E + + A E + RK L ++ ++ E E + E +L L +E +++
Sbjct: 2124 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2183
Query: 260 EEEKRDQIIQGKRTKSQELQNMVEQISLC------RAAMGRSAALRWEEKKALAAAPAAP 313
+ + + K QELQ ++Q A R AA EE + A AA
Sbjct: 2184 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2243
Query: 314 S--QDERVQQLRRRISERAAERSRQAA 338
S Q E ++L++ E+A R++ A
Sbjct: 2244 SRRQVEEAERLKQSAEEQAQARAQAQA 2270
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/290 (21%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQK---KMQAKDREEQLAASECRRLQGKLSHEEAVL 113
QVEQEL + ++ + + K +A + Q + E ++ EE
Sbjct: 2320 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2379
Query: 114 ARQSLMQENKQRVEQQKEQMAKLMLQRAE--RRLREDRSRKELVEQ--------VIEGQK 163
+ + EN+ + + K+ + + + AE +++ E+ +R + Q E
Sbjct: 2380 LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA 2439
Query: 164 NAKAAQTKLAKGRQQTVQEA--IEESRGLLQRRAQAAQEEQRR---RCELISQLRALETQ 218
+A K+ K + Q VQEA ++ LLQ++ + AQE+ RR E ++Q A ETQ
Sbjct: 2440 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2499
Query: 219 PTRKGKLVDLTQIPGYGLEGE---MSIVELRERLALLKENQR--RKEEEKRDQIIQGKRT 273
++ + + E E + + E+ A +E+ + RK+ E+ + +
Sbjct: 2500 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2559
Query: 274 KSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLR 323
+QE +V+ + + R A E L Q+ ++ QL+
Sbjct: 2560 ATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2609
Score = 43.1 bits (100), Expect = 5e-04
Identities = 73/342 (21%), Positives = 140/342 (40%), Gaps = 61/342 (17%)
Query: 46 AILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR---- 101
A + A + ++E EL R+ + E Q +++A R+ QLAA E RR
Sbjct: 2069 ASFEKAAAGKAELELELGRIRSNAEDTLRSKE----QAELEAA-RQRQLAAEEERRRREA 2123
Query: 102 ---LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQV 158
+Q L+ EE ++ E +R++ + E+ +L + + R+ + +E ++
Sbjct: 2124 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2183
Query: 159 IEGQKNAKA-AQTKLAKGRQQTVQE---AIEESRGLLQRRAQAAQEEQRRRCELISQLRA 214
++ ++ A A A + + QQT+Q+ +++ RG + +AA+E + R + +
Sbjct: 2184 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2243
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTK 274
Q VE ERL ++ E++ Q +
Sbjct: 2244 SRRQ------------------------VEEAERL--------KQSAEEQAQARAQAQAA 2271
Query: 275 SQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
+++L+ EQ R A AALR ++ AA ++ E+ ++ + + A+
Sbjct: 2272 AEKLRKEAEQ-EAARRAQAEQAALRQKQ--------AADAEMEKHKKFAEQTLRQKAQVE 2322
Query: 335 RQAALLHVSAPRTARPKPRVSPDWWEEPGRLKAGAGWGWRAR 376
++ L + T K + EE RLKA A R R
Sbjct: 2323 QELTTLRLQLEETDHQKNLLD----EELQRLKAEATEAARQR 2360
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 60.5 bits (145), Expect = 3e-09
Identities = 83/341 (24%), Positives = 150/341 (43%), Gaps = 50/341 (14%)
Query: 6 RERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQR--------- 56
++R + ++LRLQ R+ + R + V L T E L +
Sbjct: 1509 KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTA 1568
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREE--------QLAASECRRLQGKLSH 108
Q+E+ LQ V + +E Q+ + REE QL A+E RL +L
Sbjct: 1569 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL--RLQA 1626
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE V ++SL Q ++ +++ E+ A+ + E+ +R+ +EL EQ +E Q+
Sbjct: 1627 EE-VAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ----RELAEQELEKQR----- 1676
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC--ELISQLRALETQPTRKGKLV 226
+LA+G T Q+ + + L++ RA+ Q EQ+R+ E +++L+ T+K +
Sbjct: 1677 --QLAEG---TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ-- 1729
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQIS 286
E E + ++R + +L ++ R EEE R + K+ E E
Sbjct: 1730 ----------ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1779
Query: 287 LCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRIS 327
AA R+ A + ++ LA AA + E + L +++
Sbjct: 1780 --EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1818
Score = 59.3 bits (142), Expect = 7e-09
Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 28/248 (11%)
Query: 119 MQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQ 178
+ E +R+E++ E++A+ RL E + E Q+ E AKA + AK QQ
Sbjct: 1315 ISETLRRMEEE-ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1373
Query: 179 TVQEAI---EESRGLLQRRAQAAQEE---QRRRCELISQLRALETQPTRKGKL------- 225
+QE + EE+ Q++ ++ QEE R+ E Q +A + + + +L
Sbjct: 1374 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1433
Query: 226 -----VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
++ T+ G EGE+ + R A ++ Q ++E E+ + +Q + + ++
Sbjct: 1434 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ--- 1490
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
++ L + A R E+++AL A Q E + RR+ + ER+RQ +
Sbjct: 1491 --AEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAE---RRLRQAEVERARQVQVA 1544
Query: 341 HVSAPRTA 348
+A R+A
Sbjct: 1545 LETAQRSA 1552
Score = 49.3 bits (116), Expect = 7e-06
Identities = 78/351 (22%), Positives = 152/351 (43%), Gaps = 64/351 (18%)
Query: 45 TAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFE-----WQKKMQAKDREEQLAASEC 99
T + E L Q+Q E ++ +L + ++ +Q+ ++A+ + + ++E
Sbjct: 2301 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2360
Query: 100 RRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAK------------------LMLQRA 141
RL+ +++ AR +E+ QR +Q E++ + L +QR
Sbjct: 2361 ERLKLRVAEMSRAQARA---EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2417
Query: 142 E-----RRLRE-----DRSRKELVEQV----IEGQKNAKAAQTKLAKGRQQTVQEAIEES 187
+ RLRE +R +++L ++ ++ ++ Q +L + Q Q + E
Sbjct: 2418 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2477
Query: 188 RGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRE 247
LLQR + E+++ + E + Q + Q R+ + Q+ S+ E R
Sbjct: 2478 DSLLQR--ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2535
Query: 248 RLALLKENQRRKEEEKRDQIIQGKRTK----SQELQNMVEQISLC----RAAMGRSAALR 299
R +E RRK+EE + Q+ Q +R + ++E Q + EQ+ L RAA+ S +
Sbjct: 2536 RQHEAEEGVRRKQEELQ-QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2594
Query: 300 WEEKKALAA---------APAAPSQDER-VQQLRRRISERAAERSRQAALL 340
+ A PAA ++ E LRR++S A+R ++A +L
Sbjct: 2595 ASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVS---AQRLQEAGIL 2642
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 46/273 (16%)
Query: 86 QAKDREEQLAASECRRLQGKL-SHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR 144
QAK + E+ A +R+Q ++ EEA + Q + ++ ++Q ++ + +A +
Sbjct: 1359 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1418
Query: 145 LREDRSRKELVEQ--VIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+RSR + E+ V+ Q A Q A+G Q ++ EE+ ++ QA +E +
Sbjct: 1419 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA---QKRQAQEEAE 1475
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-- 260
R R R ++ + RK + VEL R+ E R K+
Sbjct: 1476 RLR-------RQVQDESQRK----------------RQAEVELASRVKAEAEAAREKQRA 1512
Query: 261 ----EEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAA---- 312
EE R Q + +R Q Q+ + RSA + K+A A A
Sbjct: 1513 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1572
Query: 313 PSQDER--VQQLRRRISERA-----AERSRQAA 338
Q+E V QLR RA AER+R+ A
Sbjct: 1573 SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1605
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/327 (23%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 48 LREGALYQRQVEQE---LQRVDK---LVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR 101
L E A QRQ+ +E QR + L + E + + + +E++ RR
Sbjct: 1787 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1846
Query: 102 LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR--LRED--RSRKELVEQ 157
L + + L Q+ ++K +E++ Q+ K ER+ L ED R R+++ E+
Sbjct: 1847 LAEDEAFQRRRLEEQAA--QHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1904
Query: 158 VIEGQKN-----AKAAQTKLAKGR-----QQTVQEAIEESRGLLQRRAQAAQEEQRRR-- 205
++ + + A A+ +L GR + T++ + ++R AA+EE+RRR
Sbjct: 1905 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1964
Query: 206 CELISQLRALETQPT--RKGKLVDLTQIPGYGLEG----EMSIVELRERLALLKENQRRK 259
E + + A E + RK L ++ ++ E E + E +L L +E +++
Sbjct: 1965 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2024
Query: 260 EEEKRDQIIQGKRTKSQELQNMVEQISLC------RAAMGRSAALRWEEKKALAAAPAAP 313
+ + + K QELQ ++Q A R AA EE + A AA
Sbjct: 2025 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2084
Query: 314 S--QDERVQQLRRRISERAAERSRQAA 338
S Q E ++L++ E+A R++ A
Sbjct: 2085 SRRQVEEAERLKQSAEEQAQARAQAQA 2111
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/290 (21%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQK---KMQAKDREEQLAASECRRLQGKLSHEEAVL 113
QVEQEL + ++ + + K +A + Q + E ++ EE
Sbjct: 2161 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2220
Query: 114 ARQSLMQENKQRVEQQKEQMAKLMLQRAE--RRLREDRSRKELVEQ--------VIEGQK 163
+ + EN+ + + K+ + + + AE +++ E+ +R + Q E
Sbjct: 2221 LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA 2280
Query: 164 NAKAAQTKLAKGRQQTVQEA--IEESRGLLQRRAQAAQEEQRR---RCELISQLRALETQ 218
+A K+ K + Q VQEA ++ LLQ++ + AQE+ RR E ++Q A ETQ
Sbjct: 2281 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2340
Query: 219 PTRKGKLVDLTQIPGYGLEGE---MSIVELRERLALLKENQR--RKEEEKRDQIIQGKRT 273
++ + + E E + + E+ A +E+ + RK+ E+ + +
Sbjct: 2341 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2400
Query: 274 KSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLR 323
+QE +V+ + + R A E L Q+ ++ QL+
Sbjct: 2401 ATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2450
Score = 43.1 bits (100), Expect = 5e-04
Identities = 73/342 (21%), Positives = 140/342 (40%), Gaps = 61/342 (17%)
Query: 46 AILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR---- 101
A + A + ++E EL R+ + E Q +++A R+ QLAA E RR
Sbjct: 1910 ASFEKAAAGKAELELELGRIRSNAEDTLRSKE----QAELEAA-RQRQLAAEEERRRREA 1964
Query: 102 ---LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQV 158
+Q L+ EE ++ E +R++ + E+ +L + + R+ + +E ++
Sbjct: 1965 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2024
Query: 159 IEGQKNAKA-AQTKLAKGRQQTVQE---AIEESRGLLQRRAQAAQEEQRRRCELISQLRA 214
++ ++ A A A + + QQT+Q+ +++ RG + +AA+E + R + +
Sbjct: 2025 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2084
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTK 274
Q VE ERL ++ E++ Q +
Sbjct: 2085 SRRQ------------------------VEEAERL--------KQSAEEQAQARAQAQAA 2112
Query: 275 SQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
+++L+ EQ R A AALR ++ AA ++ E+ ++ + + A+
Sbjct: 2113 AEKLRKEAEQ-EAARRAQAEQAALRQKQ--------AADAEMEKHKKFAEQTLRQKAQVE 2163
Query: 335 RQAALLHVSAPRTARPKPRVSPDWWEEPGRLKAGAGWGWRAR 376
++ L + T K + EE RLKA A R R
Sbjct: 2164 QELTTLRLQLEETDHQKNLLD----EELQRLKAEATEAARQR 2201
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 60.5 bits (145), Expect = 3e-09
Identities = 83/341 (24%), Positives = 150/341 (43%), Gaps = 50/341 (14%)
Query: 6 RERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQR--------- 56
++R + ++LRLQ R+ + R + V L T E L +
Sbjct: 1517 KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTA 1576
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREE--------QLAASECRRLQGKLSH 108
Q+E+ LQ V + +E Q+ + REE QL A+E RL +L
Sbjct: 1577 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL--RLQA 1634
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE V ++SL Q ++ +++ E+ A+ + E+ +R+ +EL EQ +E Q+
Sbjct: 1635 EE-VAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ----RELAEQELEKQR----- 1684
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC--ELISQLRALETQPTRKGKLV 226
+LA+G T Q+ + + L++ RA+ Q EQ+R+ E +++L+ T+K +
Sbjct: 1685 --QLAEG---TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ-- 1737
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQIS 286
E E + ++R + +L ++ R EEE R + K+ E E
Sbjct: 1738 ----------ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1787
Query: 287 LCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRIS 327
AA R+ A + ++ LA AA + E + L +++
Sbjct: 1788 --EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1826
Score = 59.3 bits (142), Expect = 7e-09
Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 28/248 (11%)
Query: 119 MQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQ 178
+ E +R+E++ E++A+ RL E + E Q+ E AKA + AK QQ
Sbjct: 1323 ISETLRRMEEE-ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1381
Query: 179 TVQEAI---EESRGLLQRRAQAAQEE---QRRRCELISQLRALETQPTRKGKL------- 225
+QE + EE+ Q++ ++ QEE R+ E Q +A + + + +L
Sbjct: 1382 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1441
Query: 226 -----VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
++ T+ G EGE+ + R A ++ Q ++E E+ + +Q + + ++
Sbjct: 1442 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ--- 1498
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
++ L + A R E+++AL A Q E + RR+ + ER+RQ +
Sbjct: 1499 --AEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAE---RRLRQAEVERARQVQVA 1552
Query: 341 HVSAPRTA 348
+A R+A
Sbjct: 1553 LETAQRSA 1560
Score = 49.3 bits (116), Expect = 7e-06
Identities = 78/351 (22%), Positives = 152/351 (43%), Gaps = 64/351 (18%)
Query: 45 TAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFE-----WQKKMQAKDREEQLAASEC 99
T + E L Q+Q E ++ +L + ++ +Q+ ++A+ + + ++E
Sbjct: 2309 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2368
Query: 100 RRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAK------------------LMLQRA 141
RL+ +++ AR +E+ QR +Q E++ + L +QR
Sbjct: 2369 ERLKLRVAEMSRAQARA---EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2425
Query: 142 E-----RRLRE-----DRSRKELVEQV----IEGQKNAKAAQTKLAKGRQQTVQEAIEES 187
+ RLRE +R +++L ++ ++ ++ Q +L + Q Q + E
Sbjct: 2426 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2485
Query: 188 RGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRE 247
LLQR + E+++ + E + Q + Q R+ + Q+ S+ E R
Sbjct: 2486 DSLLQR--ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2543
Query: 248 RLALLKENQRRKEEEKRDQIIQGKRTK----SQELQNMVEQISLC----RAAMGRSAALR 299
R +E RRK+EE + Q+ Q +R + ++E Q + EQ+ L RAA+ S +
Sbjct: 2544 RQHEAEEGVRRKQEELQ-QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2602
Query: 300 WEEKKALAA---------APAAPSQDER-VQQLRRRISERAAERSRQAALL 340
+ A PAA ++ E LRR++S A+R ++A +L
Sbjct: 2603 ASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVS---AQRLQEAGIL 2650
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 46/273 (16%)
Query: 86 QAKDREEQLAASECRRLQGKL-SHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR 144
QAK + E+ A +R+Q ++ EEA + Q + ++ ++Q ++ + +A +
Sbjct: 1367 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1426
Query: 145 LREDRSRKELVEQ--VIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+RSR + E+ V+ Q A Q A+G Q ++ EE+ ++ QA +E +
Sbjct: 1427 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA---QKRQAQEEAE 1483
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-- 260
R R R ++ + RK + VEL R+ E R K+
Sbjct: 1484 RLR-------RQVQDESQRK----------------RQAEVELASRVKAEAEAAREKQRA 1520
Query: 261 ----EEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAA---- 312
EE R Q + +R Q Q+ + RSA + K+A A A
Sbjct: 1521 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1580
Query: 313 PSQDER--VQQLRRRISERA-----AERSRQAA 338
Q+E V QLR RA AER+R+ A
Sbjct: 1581 SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1613
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/327 (23%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 48 LREGALYQRQVEQE---LQRVDK---LVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR 101
L E A QRQ+ +E QR + L + E + + + +E++ RR
Sbjct: 1795 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1854
Query: 102 LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR--LRED--RSRKELVEQ 157
L + + L Q+ ++K +E++ Q+ K ER+ L ED R R+++ E+
Sbjct: 1855 LAEDEAFQRRRLEEQAA--QHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1912
Query: 158 VIEGQKN-----AKAAQTKLAKGR-----QQTVQEAIEESRGLLQRRAQAAQEEQRRR-- 205
++ + + A A+ +L GR + T++ + ++R AA+EE+RRR
Sbjct: 1913 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1972
Query: 206 CELISQLRALETQPT--RKGKLVDLTQIPGYGLEG----EMSIVELRERLALLKENQRRK 259
E + + A E + RK L ++ ++ E E + E +L L +E +++
Sbjct: 1973 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2032
Query: 260 EEEKRDQIIQGKRTKSQELQNMVEQISLC------RAAMGRSAALRWEEKKALAAAPAAP 313
+ + + K QELQ ++Q A R AA EE + A AA
Sbjct: 2033 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2092
Query: 314 S--QDERVQQLRRRISERAAERSRQAA 338
S Q E ++L++ E+A R++ A
Sbjct: 2093 SRRQVEEAERLKQSAEEQAQARAQAQA 2119
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/290 (21%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQK---KMQAKDREEQLAASECRRLQGKLSHEEAVL 113
QVEQEL + ++ + + K +A + Q + E ++ EE
Sbjct: 2169 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2228
Query: 114 ARQSLMQENKQRVEQQKEQMAKLMLQRAE--RRLREDRSRKELVEQ--------VIEGQK 163
+ + EN+ + + K+ + + + AE +++ E+ +R + Q E
Sbjct: 2229 LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA 2288
Query: 164 NAKAAQTKLAKGRQQTVQEA--IEESRGLLQRRAQAAQEEQRR---RCELISQLRALETQ 218
+A K+ K + Q VQEA ++ LLQ++ + AQE+ RR E ++Q A ETQ
Sbjct: 2289 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2348
Query: 219 PTRKGKLVDLTQIPGYGLEGE---MSIVELRERLALLKENQR--RKEEEKRDQIIQGKRT 273
++ + + E E + + E+ A +E+ + RK+ E+ + +
Sbjct: 2349 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2408
Query: 274 KSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLR 323
+QE +V+ + + R A E L Q+ ++ QL+
Sbjct: 2409 ATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2458
Score = 43.1 bits (100), Expect = 5e-04
Identities = 73/342 (21%), Positives = 140/342 (40%), Gaps = 61/342 (17%)
Query: 46 AILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR---- 101
A + A + ++E EL R+ + E Q +++A R+ QLAA E RR
Sbjct: 1918 ASFEKAAAGKAELELELGRIRSNAEDTLRSKE----QAELEAA-RQRQLAAEEERRRREA 1972
Query: 102 ---LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQV 158
+Q L+ EE ++ E +R++ + E+ +L + + R+ + +E ++
Sbjct: 1973 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2032
Query: 159 IEGQKNAKA-AQTKLAKGRQQTVQE---AIEESRGLLQRRAQAAQEEQRRRCELISQLRA 214
++ ++ A A A + + QQT+Q+ +++ RG + +AA+E + R + +
Sbjct: 2033 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2092
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTK 274
Q VE ERL ++ E++ Q +
Sbjct: 2093 SRRQ------------------------VEEAERL--------KQSAEEQAQARAQAQAA 2120
Query: 275 SQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
+++L+ EQ R A AALR ++ AA ++ E+ ++ + + A+
Sbjct: 2121 AEKLRKEAEQ-EAARRAQAEQAALRQKQ--------AADAEMEKHKKFAEQTLRQKAQVE 2171
Query: 335 RQAALLHVSAPRTARPKPRVSPDWWEEPGRLKAGAGWGWRAR 376
++ L + T K + EE RLKA A R R
Sbjct: 2172 QELTTLRLQLEETDHQKNLLD----EELQRLKAEATEAARQR 2209
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 60.5 bits (145), Expect = 3e-09
Identities = 83/341 (24%), Positives = 150/341 (43%), Gaps = 50/341 (14%)
Query: 6 RERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQR--------- 56
++R + ++LRLQ R+ + R + V L T E L +
Sbjct: 1558 KQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTA 1617
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREE--------QLAASECRRLQGKLSH 108
Q+E+ LQ V + +E Q+ + REE QL A+E RL +L
Sbjct: 1618 QLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL--RLQA 1675
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE V ++SL Q ++ +++ E+ A+ + E+ +R+ +EL EQ +E Q+
Sbjct: 1676 EE-VAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQ----RELAEQELEKQR----- 1725
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC--ELISQLRALETQPTRKGKLV 226
+LA+G T Q+ + + L++ RA+ Q EQ+R+ E +++L+ T+K +
Sbjct: 1726 --QLAEG---TAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQ-- 1778
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQIS 286
E E + ++R + +L ++ R EEE R + K+ E E
Sbjct: 1779 ----------ELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAE 1828
Query: 287 LCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRIS 327
AA R+ A + ++ LA AA + E + L +++
Sbjct: 1829 --EAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLA 1867
Score = 59.3 bits (142), Expect = 7e-09
Identities = 60/248 (24%), Positives = 113/248 (45%), Gaps = 28/248 (11%)
Query: 119 MQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQ 178
+ E +R+E++ E++A+ RL E + E Q+ E AKA + AK QQ
Sbjct: 1364 ISETLRRMEEE-ERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ 1422
Query: 179 TVQEAI---EESRGLLQRRAQAAQEE---QRRRCELISQLRALETQPTRKGKL------- 225
+QE + EE+ Q++ ++ QEE R+ E Q +A + + + +L
Sbjct: 1423 RMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIR 1482
Query: 226 -----VDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
++ T+ G EGE+ + R A ++ Q ++E E+ + +Q + + ++
Sbjct: 1483 VVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQ--- 1539
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
++ L + A R E+++AL A Q E + RR+ + ER+RQ +
Sbjct: 1540 --AEVELASRVKAEAEAAR-EKQRALQALEELRLQAEEAE---RRLRQAEVERARQVQVA 1593
Query: 341 HVSAPRTA 348
+A R+A
Sbjct: 1594 LETAQRSA 1601
Score = 49.3 bits (116), Expect = 7e-06
Identities = 78/351 (22%), Positives = 152/351 (43%), Gaps = 64/351 (18%)
Query: 45 TAILREGALYQRQVEQELQRVDKLVDGAGDFSEFFE-----WQKKMQAKDREEQLAASEC 99
T + E L Q+Q E ++ +L + ++ +Q+ ++A+ + + ++E
Sbjct: 2350 TRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEA 2409
Query: 100 RRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAK------------------LMLQRA 141
RL+ +++ AR +E+ QR +Q E++ + L +QR
Sbjct: 2410 ERLKLRVAEMSRAQARA---EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQ 2466
Query: 142 E-----RRLRE-----DRSRKELVEQV----IEGQKNAKAAQTKLAKGRQQTVQEAIEES 187
+ RLRE +R +++L ++ ++ ++ Q +L + Q Q + E
Sbjct: 2467 QSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEK 2526
Query: 188 RGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRE 247
LLQR + E+++ + E + Q + Q R+ + Q+ S+ E R
Sbjct: 2527 DSLLQR--ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARR 2584
Query: 248 RLALLKENQRRKEEEKRDQIIQGKRTK----SQELQNMVEQISLC----RAAMGRSAALR 299
R +E RRK+EE + Q+ Q +R + ++E Q + EQ+ L RAA+ S +
Sbjct: 2585 RQHEAEEGVRRKQEELQ-QLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVT 2643
Query: 300 WEEKKALAA---------APAAPSQDER-VQQLRRRISERAAERSRQAALL 340
+ A PAA ++ E LRR++S A+R ++A +L
Sbjct: 2644 ASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVS---AQRLQEAGIL 2691
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 46/273 (16%)
Query: 86 QAKDREEQLAASECRRLQGKL-SHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR 144
QAK + E+ A +R+Q ++ EEA + Q + ++ ++Q ++ + +A +
Sbjct: 1408 QAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQA 1467
Query: 145 LREDRSRKELVEQ--VIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQ 202
+RSR + E+ V+ Q A Q A+G Q ++ EE+ ++ QA +E +
Sbjct: 1468 EAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEA---QKRQAQEEAE 1524
Query: 203 RRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-- 260
R R R ++ + RK + VEL R+ E R K+
Sbjct: 1525 RLR-------RQVQDESQRK----------------RQAEVELASRVKAEAEAAREKQRA 1561
Query: 261 ----EEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAA---- 312
EE R Q + +R Q Q+ + RSA + K+A A A
Sbjct: 1562 LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLER 1621
Query: 313 PSQDER--VQQLRRRISERA-----AERSRQAA 338
Q+E V QLR RA AER+R+ A
Sbjct: 1622 SLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1654
Score = 47.4 bits (111), Expect = 3e-05
Identities = 78/327 (23%), Positives = 142/327 (43%), Gaps = 38/327 (11%)
Query: 48 LREGALYQRQVEQE---LQRVDK---LVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR 101
L E A QRQ+ +E QR + L + E + + + +E++ RR
Sbjct: 1836 LAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRR 1895
Query: 102 LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERR--LRED--RSRKELVEQ 157
L + + L Q+ ++K +E++ Q+ K ER+ L ED R R+++ E+
Sbjct: 1896 LAEDEAFQRRRLEEQAA--QHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1953
Query: 158 VIEGQKN-----AKAAQTKLAKGR-----QQTVQEAIEESRGLLQRRAQAAQEEQRRR-- 205
++ + + A A+ +L GR + T++ + ++R AA+EE+RRR
Sbjct: 1954 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 2013
Query: 206 CELISQLRALETQPT--RKGKLVDLTQIPGYGLEG----EMSIVELRERLALLKENQRRK 259
E + + A E + RK L ++ ++ E E + E +L L +E +++
Sbjct: 2014 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2073
Query: 260 EEEKRDQIIQGKRTKSQELQNMVEQISLC------RAAMGRSAALRWEEKKALAAAPAAP 313
+ + + K QELQ ++Q A R AA EE + A AA
Sbjct: 2074 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2133
Query: 314 S--QDERVQQLRRRISERAAERSRQAA 338
S Q E ++L++ E+A R++ A
Sbjct: 2134 SRRQVEEAERLKQSAEEQAQARAQAQA 2160
Score = 44.3 bits (103), Expect = 2e-04
Identities = 61/290 (21%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 57 QVEQELQRVDKLVDGAGDFSEFFEWQK---KMQAKDREEQLAASECRRLQGKLSHEEAVL 113
QVEQEL + ++ + + K +A + Q + E ++ EE
Sbjct: 2210 QVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSK 2269
Query: 114 ARQSLMQENKQRVEQQKEQMAKLMLQRAE--RRLREDRSRKELVEQ--------VIEGQK 163
+ + EN+ + + K+ + + + AE +++ E+ +R + Q E
Sbjct: 2270 LKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLA 2329
Query: 164 NAKAAQTKLAKGRQQTVQEA--IEESRGLLQRRAQAAQEEQRR---RCELISQLRALETQ 218
+A K+ K + Q VQEA ++ LLQ++ + AQE+ RR E ++Q A ETQ
Sbjct: 2330 QQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQ 2389
Query: 219 PTRKGKLVDLTQIPGYGLEGE---MSIVELRERLALLKENQR--RKEEEKRDQIIQGKRT 273
++ + + E E + + E+ A +E+ + RK+ E+ + +
Sbjct: 2390 GFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTEL 2449
Query: 274 KSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLR 323
+QE +V+ + + R A E L Q+ ++ QL+
Sbjct: 2450 ATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLK 2499
Score = 43.1 bits (100), Expect = 5e-04
Identities = 73/342 (21%), Positives = 140/342 (40%), Gaps = 61/342 (17%)
Query: 46 AILREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRR---- 101
A + A + ++E EL R+ + E Q +++A R+ QLAA E RR
Sbjct: 1959 ASFEKAAAGKAELELELGRIRSNAEDTLRSKE----QAELEAA-RQRQLAAEEERRRREA 2013
Query: 102 ---LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQV 158
+Q L+ EE ++ E +R++ + E+ +L + + R+ + +E ++
Sbjct: 2014 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2073
Query: 159 IEGQKNAKA-AQTKLAKGRQQTVQE---AIEESRGLLQRRAQAAQEEQRRRCELISQLRA 214
++ ++ A A A + + QQT+Q+ +++ RG + +AA+E + R + +
Sbjct: 2074 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2133
Query: 215 LETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTK 274
Q VE ERL ++ E++ Q +
Sbjct: 2134 SRRQ------------------------VEEAERL--------KQSAEEQAQARAQAQAA 2161
Query: 275 SQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
+++L+ EQ R A AALR ++ AA ++ E+ ++ + + A+
Sbjct: 2162 AEKLRKEAEQ-EAARRAQAEQAALRQKQ--------AADAEMEKHKKFAEQTLRQKAQVE 2212
Query: 335 RQAALLHVSAPRTARPKPRVSPDWWEEPGRLKAGAGWGWRAR 376
++ L + T K + EE RLKA A R R
Sbjct: 2213 QELTTLRLQLEETDHQKNLLD----EELQRLKAEATEAARQR 2250
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 60.1 bits (144), Expect = 4e-09
Identities = 65/334 (19%), Positives = 150/334 (44%), Gaps = 25/334 (7%)
Query: 48 LREGALYQRQVEQELQRVDKLV---DGAGDFSEFFEWQKKMQAKDREEQLAASE--CRRL 102
+RE R+ E++++R ++++ + E W+K+ + + +EE + E R L
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 443
Query: 103 QGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLRED----RSRKELV--- 155
+ K+ +E + ++ QE ++ EQ+K Q + + R E ++RE R ++E +
Sbjct: 444 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 156 EQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRAL 215
E+ I Q+ + + + + +E I E + +++ + ++E++ R + R
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQE 563
Query: 216 ETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEE---EKRDQIIQGKR 272
E ++ K+ + + E I E E++ +E R +EE E+ +++ + +
Sbjct: 564 EKMHDQEEKIREQEE---KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620
Query: 273 TKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAE 332
++ + M EQ R + +R +EKK Q+E +Q+ ++ E+ +
Sbjct: 621 KMCEQEEKMQEQEEKMRR---QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 677
Query: 333 RSRQAALLHVSAPRTARPKPRVSPDWWEEPGRLK 366
Q + + R + ++ WE+ RL+
Sbjct: 678 MCEQEEKMQEQEEKMRRQEEKM----WEQEVRLR 707
Score = 45.8 bits (107), Expect = 8e-05
Identities = 66/369 (17%), Positives = 158/369 (42%), Gaps = 42/369 (11%)
Query: 9 VQGSKQQLRLQFPPRIRKTPKLTFYRPDNIL-------------VKLNTTAILREGALYQ 55
V+ K +++L RK + P L V A + E L+
Sbjct: 294 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 353
Query: 56 R---QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAV 112
R Q E+++ R ++ + EW++K+Q ++EE++ R + K+ +E
Sbjct: 354 RLNQQQEEKMWRQEEKIQ---------EWEEKIQ--EQEEKI-----REQEEKIREQEEK 397
Query: 113 LARQ-SLMQENKQRVEQQKEQM--AKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQ 169
+ RQ +M E ++++ +Q+E M + ++R E + E + +E+ + Q+ + +
Sbjct: 398 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 457
Query: 170 TKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLT 229
K + + QE +E + R+ + +E++ + E ++ E + + K+ +
Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE 517
Query: 230 QIPGYGLEGEMSIVE--LRERLALLKENQRRKEEEKRDQIIQGKRTKSQE-LQNMVEQIS 286
+ + EM E +RE+ + ++ ++ E+E++ + + K + +E + + E+I
Sbjct: 518 KRQE---QEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR 574
Query: 287 LCRAAMGR-SAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAP 345
+ R +R +E+K Q+E Q+ ++ E+ + Q +
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634
Query: 346 RTARPKPRV 354
+ R + ++
Sbjct: 635 KMRRQEEKI 643
Score = 36.6 bits (83), Expect = 0.049
Identities = 30/163 (18%), Positives = 75/163 (46%), Gaps = 12/163 (7%)
Query: 7 ERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQELQRVD 66
E++ ++++R Q R+ K+ R ++ I + + Q Q E+ ++ +
Sbjct: 564 EKMHDQEEKIREQEEKVWRQEEKI---REQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620
Query: 67 KLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRV 126
K+ + E E ++ + K RE++ E EE + ++ +MQE ++++
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE---------QEEKIREQEEMMQEQEEKM 671
Query: 127 EQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQ 169
+Q+E+M + + E+ + R +++ EQ + ++ + Q
Sbjct: 672 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Score = 33.1 bits (74), Expect = 0.54
Identities = 43/253 (16%), Positives = 96/253 (37%), Gaps = 32/253 (12%)
Query: 142 ERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEE 201
E+ L ++K+ ++ IE + A + L R E ++E LQ + Q + E
Sbjct: 239 EQALSAVATQKKKADRYIEELTKERDALS-LELYRNTITDEELKEKNAKLQEKLQLVESE 297
Query: 202 QRR-------------RCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRER 248
+ R +L+ + L+ + GK + Q L+ ++ EL R
Sbjct: 298 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL---QSVSAKLQAQVEENELWNR 354
Query: 249 LALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWE------- 301
L +E + ++EEK + + + + ++++ E+I M R + WE
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414
Query: 302 --------EKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPKPR 353
E+K ++E++++L ++ E+ R ++ R +
Sbjct: 415 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 474
Query: 354 VSPDWWEEPGRLK 366
W + +++
Sbjct: 475 QEAKMWRQEEKIR 487
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 58.9 bits (141), Expect = 9e-09
Identities = 72/298 (24%), Positives = 132/298 (44%), Gaps = 27/298 (9%)
Query: 49 REGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSH 108
+E +R +E EL+ G+ S+ + QK++ K +EE + RRL+ ++ +
Sbjct: 888 KEAVSARRALENELEAAQ------GNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMEN 941
Query: 109 EEAVLAR--QSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAK 166
E L + + L +E VE + +L Q E + + R E+ Q+ E K +
Sbjct: 942 ERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKE--KTLE 999
Query: 167 AAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQ-LRALETQPTRKGKL 225
A +++L + Q +EE R Q AQ+E + +L+ Q L+ LE + K L
Sbjct: 1000 AEKSRLTAMKMQDEMRLMEEE----LRDYQRAQDEALTKRQLLEQTLKDLEYELEAKSHL 1055
Query: 226 VD-----LTQIPGYGLEGEMSIVELRERLALLKE---NQRRKEEEKRDQIIQGKRTKSQE 277
D + Q+ + EM + E R LL E R + E+ R++++Q +R Q+
Sbjct: 1056 KDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQ-ERAARQD 1114
Query: 278 LQNMVEQISLCRAAMG-RSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS 334
L+ ++ISL R +S + E + + R+ +L R+ +R+
Sbjct: 1115 LE--CDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRA 1170
Score = 44.7 bits (104), Expect = 2e-04
Identities = 66/314 (21%), Positives = 138/314 (43%), Gaps = 61/314 (19%)
Query: 77 EFFEWQKKMQAKDREEQLAASECRRLQGKLS-----HEEAVLARQSLMQ---ENKQRVEQ 128
E E Q+++Q + + +Q E R++ L H E V +L Q E++ + +
Sbjct: 622 EVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRK 681
Query: 129 QKEQMAKLMLQRAERRLR---------------------EDRSRKELVEQVIEGQKN--- 164
E++ ++ ++R + + EDR + L+E++++ +++
Sbjct: 682 NLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQD 741
Query: 165 ---AKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTR 221
AK Q L + R+ +E L + + QE + + + ++L+AL
Sbjct: 742 LLIAKEEQEDLLRKRE---RELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE 798
Query: 222 KGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQR---RKEE--------EKRDQIIQG 270
K V++ E + + E+R +L L +EN++ R EE +++ + ++G
Sbjct: 799 ATKNVEVLASRSNTSEQDQAGTEMRVKL-LQEENEKLQGRSEELERRVAQLQRQIEDLKG 857
Query: 271 KRTKSQE-LQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQ-------QL 322
K++E L+ +I A+ + R EEK+A++A A ++ E Q Q
Sbjct: 858 DEAKAKETLKKYEGEIRQLEEALVHA---RKEEKEAVSARRALENELEAAQGNLSQTTQE 914
Query: 323 RRRISERAAERSRQ 336
++++SE+ E S Q
Sbjct: 915 QKQLSEKLKEESEQ 928
Score = 38.5 bits (88), Expect = 0.013
Identities = 52/257 (20%), Positives = 95/257 (36%), Gaps = 48/257 (18%)
Query: 102 LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEG 161
L+ + S E V+ SL ++K+ E+ K A LMLQ D K++ +
Sbjct: 471 LETEGSQESTVIRAPSLGAQSKKE-EEVKTATATLMLQNRATATSPDSGAKKISVKTFPS 529
Query: 162 QKNAKAAQTKLAKGRQQTVQEAIEESRG------------------------------LL 191
N +A L KG+Q+ Q+ EE+ L
Sbjct: 530 ASNTQATPD-LLKGQQELTQQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFEKIQTL 588
Query: 192 QRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLAL 251
+ RA + + + C S+++ L Q K KL + + EL+ +L L
Sbjct: 589 KSRAAGSAQGNNQACNSTSEVKDLLEQ---KSKLT-------------IEVAELQRQLQL 632
Query: 252 LKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPA 311
+NQ+ +EE+ + +SQ + + E +L + LR ++
Sbjct: 633 EVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKME 692
Query: 312 APSQDERVQQLRRRISE 328
++ L+ ++SE
Sbjct: 693 REQHQTEIRDLQDQLSE 709
>gi|239756174 PREDICTED: hypothetical protein [Homo sapiens]
Length = 625
Score = 58.5 bits (140), Expect = 1e-08
Identities = 66/271 (24%), Positives = 118/271 (43%), Gaps = 45/271 (16%)
Query: 80 EWQKKMQAKDREEQLAASECRRLQGKLSHEE--AVLARQSLMQENKQRVEQQKEQMAKLM 137
E ++K +A ++ + A++ +G+ EE A RQ + +++R + E+ L
Sbjct: 395 EEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAERQGLLR 454
Query: 138 LQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQ- 196
+RAER REDR RK EQ + K R++ +QE E + + + RAQ
Sbjct: 455 RERAERAAREDRLRKLQQEQNL--------------KQREEGLQEGRERAEQIRRERAQR 500
Query: 197 AAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQ 256
AA+ +QR+ +L + R E+S E R R L + +
Sbjct: 501 AARAKQRQEGQLQREKR-------------------------ELSRAE-RARHEALLQGR 534
Query: 257 RRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQD 316
R++ ++R+ + Q E +++ R + RS L E + AL +A +
Sbjct: 535 TRQQRQEREGLRSSLEASLGRAQENYEHLAIGR-KLERSEQLTRERRSALESARSTARAS 593
Query: 317 ERV-QQLRRRISERAAERSRQAALLHVSAPR 346
V +++R + R+ +R + A LH S R
Sbjct: 594 FHVREKVREETNTRSFDRMVREAQLHASLDR 624
Score = 50.1 bits (118), Expect = 4e-06
Identities = 63/244 (25%), Positives = 104/244 (42%), Gaps = 23/244 (9%)
Query: 120 QENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQT 179
QE +EQ+ + LQR + R +R +E ++ +E + A AAQ + +GR+
Sbjct: 365 QEELLLLEQRAAAHGQWELQRVHAKQRREREERE-KQRALEQGRRAWAAQVEERRGRRG- 422
Query: 180 VQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGE 239
E R +RR + + + RR EL + L + + D + L+ E
Sbjct: 423 -----REEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLR----KLQQE 473
Query: 240 MSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKS-QELQNMVEQISLCRAAMGRSAAL 298
+ L++R L+E + R E+ +R++ + R K QE Q E+ L RA R AL
Sbjct: 474 QN---LKQREEGLQEGRERAEQIRRERAQRAARAKQRQEGQLQREKRELSRAERARHEAL 530
Query: 299 -------RWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPK 351
+ +E++ L ++ A S + R ERS Q SA +AR
Sbjct: 531 LQGRTRQQRQEREGLRSSLEA-SLGRAQENYEHLAIGRKLERSEQLTRERRSALESARST 589
Query: 352 PRVS 355
R S
Sbjct: 590 ARAS 593
>gi|239750672 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 58.5 bits (140), Expect = 1e-08
Identities = 66/271 (24%), Positives = 118/271 (43%), Gaps = 45/271 (16%)
Query: 80 EWQKKMQAKDREEQLAASECRRLQGKLSHEE--AVLARQSLMQENKQRVEQQKEQMAKLM 137
E ++K +A ++ + A++ +G+ EE A RQ + +++R + E+ L
Sbjct: 397 EEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAERQGLLR 456
Query: 138 LQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQ- 196
+RAER REDR RK EQ + K R++ +QE E + + + RAQ
Sbjct: 457 RERAERAAREDRLRKLQQEQNL--------------KQREEGLQEGRERAEQIRRERAQR 502
Query: 197 AAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQ 256
AA+ +QR+ +L + R E+S E R R L + +
Sbjct: 503 AARAKQRQEGQLQREKR-------------------------ELSRAE-RARHEALLQGR 536
Query: 257 RRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQD 316
R++ ++R+ + Q E +++ R + RS L E + AL +A +
Sbjct: 537 TRQQRQEREGLRSSLEASLGRAQENYEHLAIGR-KLERSEQLTRERRSALESARSTARAS 595
Query: 317 ERV-QQLRRRISERAAERSRQAALLHVSAPR 346
V +++R + R+ +R + A LH S R
Sbjct: 596 FHVREKVREETNTRSFDRMVREAQLHASLDR 626
Score = 50.1 bits (118), Expect = 4e-06
Identities = 63/244 (25%), Positives = 104/244 (42%), Gaps = 23/244 (9%)
Query: 120 QENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQT 179
QE +EQ+ + LQR + R +R +E ++ +E + A AAQ + +GR+
Sbjct: 367 QEELLLLEQRAAAHGQWELQRVHAKQRREREERE-KQRALEQGRRAWAAQVEERRGRRG- 424
Query: 180 VQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGE 239
E R +RR + + + RR EL + L + + D + L+ E
Sbjct: 425 -----REEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLR----KLQQE 475
Query: 240 MSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKS-QELQNMVEQISLCRAAMGRSAAL 298
+ L++R L+E + R E+ +R++ + R K QE Q E+ L RA R AL
Sbjct: 476 QN---LKQREEGLQEGRERAEQIRRERAQRAARAKQRQEGQLQREKRELSRAERARHEAL 532
Query: 299 -------RWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPK 351
+ +E++ L ++ A S + R ERS Q SA +AR
Sbjct: 533 LQGRTRQQRQEREGLRSSLEA-SLGRAQENYEHLAIGRKLERSEQLTRERRSALESARST 591
Query: 352 PRVS 355
R S
Sbjct: 592 ARAS 595
>gi|239744982 PREDICTED: hypothetical protein [Homo sapiens]
Length = 627
Score = 58.5 bits (140), Expect = 1e-08
Identities = 66/271 (24%), Positives = 118/271 (43%), Gaps = 45/271 (16%)
Query: 80 EWQKKMQAKDREEQLAASECRRLQGKLSHEE--AVLARQSLMQENKQRVEQQKEQMAKLM 137
E ++K +A ++ + A++ +G+ EE A RQ + +++R + E+ L
Sbjct: 397 EEREKQRALEQGRRAWAAQVEERRGRRGREEREAARRRQRQYERSEERRRELAERQGLLR 456
Query: 138 LQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQ- 196
+RAER REDR RK EQ + K R++ +QE E + + + RAQ
Sbjct: 457 RERAERAAREDRLRKLQQEQNL--------------KQREEGLQEGRERAEQIRRERAQR 502
Query: 197 AAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQ 256
AA+ +QR+ +L + R E+S E R R L + +
Sbjct: 503 AARAKQRQEGQLQREKR-------------------------ELSRAE-RARHEALLQGR 536
Query: 257 RRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQD 316
R++ ++R+ + Q E +++ R + RS L E + AL +A +
Sbjct: 537 TRQQRQEREGLRSSLEASLGRAQENYEHLAIGR-KLERSEQLTRERRSALESARSTARAS 595
Query: 317 ERV-QQLRRRISERAAERSRQAALLHVSAPR 346
V +++R + R+ +R + A LH S R
Sbjct: 596 FHVREKVREETNTRSFDRMVREAQLHASLDR 626
Score = 50.1 bits (118), Expect = 4e-06
Identities = 63/244 (25%), Positives = 104/244 (42%), Gaps = 23/244 (9%)
Query: 120 QENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQT 179
QE +EQ+ + LQR + R +R +E ++ +E + A AAQ + +GR+
Sbjct: 367 QEELLLLEQRAAAHGQWELQRVHAKQRREREERE-KQRALEQGRRAWAAQVEERRGRRG- 424
Query: 180 VQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGE 239
E R +RR + + + RR EL + L + + D + L+ E
Sbjct: 425 -----REEREAARRRQRQYERSEERRRELAERQGLLRRERAERAAREDRLR----KLQQE 475
Query: 240 MSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKS-QELQNMVEQISLCRAAMGRSAAL 298
+ L++R L+E + R E+ +R++ + R K QE Q E+ L RA R AL
Sbjct: 476 QN---LKQREEGLQEGRERAEQIRRERAQRAARAKQRQEGQLQREKRELSRAERARHEAL 532
Query: 299 -------RWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALLHVSAPRTARPK 351
+ +E++ L ++ A S + R ERS Q SA +AR
Sbjct: 533 LQGRTRQQRQEREGLRSSLEA-SLGRAQENYEHLAIGRKLERSEQLTRERRSALESARST 591
Query: 352 PRVS 355
R S
Sbjct: 592 ARAS 595
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 58.5 bits (140), Expect = 1e-08
Identities = 70/321 (21%), Positives = 145/321 (45%), Gaps = 34/321 (10%)
Query: 50 EGALYQRQVEQELQRVDKLVDGAGDFSEF-FEWQKKMQAKDREEQL---AASECRRLQGK 105
E + + ++ EL+++DKL E +++++ +RE Q A E +RLQ +
Sbjct: 1367 EASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQR 1426
Query: 106 LS--HEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQK 163
L+ +E AR+ + K ++Q +Q + L R + L E++ R++L+E +E +
Sbjct: 1427 LAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQ--LEEEQHRRQLLEGELETLR 1484
Query: 164 NAKAAQTKLAKGRQQTVQEAIEESRG----LLQRRAQAAQEEQRRRCELISQLRALETQP 219
AA K + + E+++ +G +QR + +EE R + EL ++ LE +
Sbjct: 1485 RKLAALEKAEVKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEAR- 1543
Query: 220 TRKGKLVDLTQIPGYGLEGEMSIVELRERLALLK-ENQRRKEEEKRDQI-IQGKRTKSQE 277
L+++ + + + LRE L+ E Q + E +R Q I T++++
Sbjct: 1544 --------LSELEFHNSKSSKELDFLREENHKLQLERQNLQLETRRLQSEINMAATETRD 1595
Query: 278 LQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERS--- 334
L+NM ++ + + L E++ + +D + +L++R+ A +R
Sbjct: 1596 LRNM----TVADSGTNHDSRLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKREQRE 1651
Query: 335 ----RQAALLHVSAPRTARPK 351
R ++H R P+
Sbjct: 1652 NHLRRSIVVIHPDTGRELSPE 1672
Score = 43.5 bits (101), Expect = 4e-04
Identities = 70/321 (21%), Positives = 135/321 (42%), Gaps = 55/321 (17%)
Query: 57 QVEQELQRV-DKLVDGAGDFS----EFFEWQKKMQA-KDREEQLAASECRR-----LQGK 105
++E+ELQR+ +++VD E ++ +K++QA KD + Q+ E + +
Sbjct: 1243 EMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDP 1302
Query: 106 LSHEEAVLARQSLMQENKQRVEQQKEQMAKL-MLQRAERRLREDRSRKELVEQVI---EG 161
+ EE R L +E K++V+ ++E+ ++ + R E L R ++ +V+Q + E
Sbjct: 1303 QTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEEL--SRVKERVVQQEVVRYEE 1360
Query: 162 QKNAKAAQTKLAKG----------------RQQTVQEAIEESRGLLQRRAQAAQEEQRRR 205
+ +A + A+ R Q + +E L+R QA +E +R
Sbjct: 1361 EPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELERERQARREAEREV 1420
Query: 206 CELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRD 265
L +L ALE + + V TQ + + + RL L +EE+ R
Sbjct: 1421 QRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQL-------EEEQHRR 1473
Query: 266 QIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRR 325
Q+++G EL+ + +++ A E K+ + + + + +Q +R
Sbjct: 1474 QLLEG------ELETLRRKLAALEKA---------EVKEKVVLSESVQVEKGDTEQEIQR 1518
Query: 326 ISERAAERSRQAALLHVSAPR 346
+ E SR L V R
Sbjct: 1519 LKSSLEEESRSKRELDVEVSR 1539
Score = 38.1 bits (87), Expect = 0.017
Identities = 55/257 (21%), Positives = 117/257 (45%), Gaps = 24/257 (9%)
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQ-RAERRLREDRSRKELVEQVIEGQKNAKA 167
EE+ Q + E + + + +E++ L LQ RA + D ++ +V++V+ + + +A
Sbjct: 947 EESFQQLQRTLAEEQHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPD-RA 1005
Query: 168 AQTKLAKGRQQTVQEAIEESRG-------LLQRRAQAAQEEQRRRCELISQLRALETQPT 220
++ + R++ EA+ +G LLQ+R A EE+ R E +++ ++ Q
Sbjct: 1006 QADEVLQLREEL--EALRRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQND 1063
Query: 221 RKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
+ + + Q+ + + E L+ L++ +R E+E+ + +GK T + L+
Sbjct: 1064 PQLE-AEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKER--AMAEGKITVKEVLK- 1119
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
VE+ + + ++E++ AA A SQ E+ + LR+ A E ++
Sbjct: 1120 -VEKDAATEREVS-DLTRQYEDE----AAKARASQREKTELLRK---IWALEEENAKVVV 1170
Query: 341 HVSAPRTARPKPRVSPD 357
RP P+ +
Sbjct: 1171 QEKVREIVRPDPKAESE 1187
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 57.4 bits (137), Expect = 3e-08
Identities = 74/312 (23%), Positives = 140/312 (44%), Gaps = 30/312 (9%)
Query: 49 REGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSH 108
RE + ++ E+E +R ++L E Q++ + K REE+ A RR Q
Sbjct: 736 REAEMRAKREEEERKRQEEL---RRQQEEILRRQQEEERKRREEEELA---RRKQ----- 784
Query: 109 EEAVLA-RQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRK--ELV----EQVIEG 161
EEA+ R+ + +QR E++++Q + + + ERR E+ RK EL+ E+ +
Sbjct: 785 EEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW 844
Query: 162 QKNAKAAQTKLAKGRQQTVQEAI-----EESRGLLQRRAQAAQEEQRRRCELISQLRALE 216
+ + AQ +L + R + +EA EE R + Q +E R+R + LR L+
Sbjct: 845 AREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ 904
Query: 217 TQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQ 276
Q ++ +L + ++P G+ S + A L + +K EE+R++ ++ ++ + Q
Sbjct: 905 QQQQQQ-QLAQM-KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQ 962
Query: 277 E-----LQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAA 331
LQ +Q + G + K L Q ++ QQ +++ +
Sbjct: 963 RELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1022
Query: 332 ERSRQAALLHVS 343
R+ + LH S
Sbjct: 1023 ARNNTHSNLHTS 1034
Score = 49.7 bits (117), Expect = 6e-06
Identities = 55/265 (20%), Positives = 120/265 (45%), Gaps = 23/265 (8%)
Query: 87 AKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLR 146
A ++ +QL ++ +L+ + E R+ ++ ++ + +Q+E++ + + +R
Sbjct: 716 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
Query: 147 EDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC 206
E+ + E+ + Q+ + ++A RQ+ +E ++ L + + +EE+RR+
Sbjct: 776 EEELARRKQEEALRRQR-----EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 830
Query: 207 ELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-EEKRD 265
E + LR E + + + + Q E + + E RL +E ++RKE E +R
Sbjct: 831 EEL--LRKQEEEAAKWAREEEEAQ--RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 886
Query: 266 QIIQGKRTKSQE----LQNMVEQISLCRAAMGRSA-------ALRWEEKKALAAAPAAPS 314
+ + +R + QE LQ +Q L + + S+ + + L+ A
Sbjct: 887 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 946
Query: 315 QDERVQQLRRRISERAAERSRQAAL 339
++ER +QLR +R +R AL
Sbjct: 947 EEERERQLRE--EQRRQQRELMKAL 969
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 57.4 bits (137), Expect = 3e-08
Identities = 74/312 (23%), Positives = 140/312 (44%), Gaps = 30/312 (9%)
Query: 49 REGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSH 108
RE + ++ E+E +R ++L E Q++ + K REE+ A RR Q
Sbjct: 763 REAEMRAKREEEERKRQEEL---RRQQEEILRRQQEEERKRREEEELA---RRKQ----- 811
Query: 109 EEAVLA-RQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRK--ELV----EQVIEG 161
EEA+ R+ + +QR E++++Q + + + ERR E+ RK EL+ E+ +
Sbjct: 812 EEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW 871
Query: 162 QKNAKAAQTKLAKGRQQTVQEAI-----EESRGLLQRRAQAAQEEQRRRCELISQLRALE 216
+ + AQ +L + R + +EA EE R + Q +E R+R + LR L+
Sbjct: 872 AREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ 931
Query: 217 TQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQ 276
Q ++ +L + ++P G+ S + A L + +K EE+R++ ++ ++ + Q
Sbjct: 932 QQQQQQ-QLAQM-KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQ 989
Query: 277 E-----LQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAA 331
LQ +Q + G + K L Q ++ QQ +++ +
Sbjct: 990 RELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1049
Query: 332 ERSRQAALLHVS 343
R+ + LH S
Sbjct: 1050 ARNNTHSNLHTS 1061
Score = 49.7 bits (117), Expect = 6e-06
Identities = 55/265 (20%), Positives = 120/265 (45%), Gaps = 23/265 (8%)
Query: 87 AKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLR 146
A ++ +QL ++ +L+ + E R+ ++ ++ + +Q+E++ + + +R
Sbjct: 743 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
Query: 147 EDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC 206
E+ + E+ + Q+ + ++A RQ+ +E ++ L + + +EE+RR+
Sbjct: 803 EEELARRKQEEALRRQR-----EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 857
Query: 207 ELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-EEKRD 265
E + LR E + + + + Q E + + E RL +E ++RKE E +R
Sbjct: 858 EEL--LRKQEEEAAKWAREEEEAQ--RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 913
Query: 266 QIIQGKRTKSQE----LQNMVEQISLCRAAMGRSA-------ALRWEEKKALAAAPAAPS 314
+ + +R + QE LQ +Q L + + S+ + + L+ A
Sbjct: 914 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 973
Query: 315 QDERVQQLRRRISERAAERSRQAAL 339
++ER +QLR +R +R AL
Sbjct: 974 EEERERQLRE--EQRRQQRELMKAL 996
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 57.4 bits (137), Expect = 3e-08
Identities = 74/312 (23%), Positives = 140/312 (44%), Gaps = 30/312 (9%)
Query: 49 REGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSH 108
RE + ++ E+E +R ++L E Q++ + K REE+ A RR Q
Sbjct: 742 REAEMRAKREEEERKRQEEL---RRQQEEILRRQQEEERKRREEEELA---RRKQ----- 790
Query: 109 EEAVLA-RQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRK--ELV----EQVIEG 161
EEA+ R+ + +QR E++++Q + + + ERR E+ RK EL+ E+ +
Sbjct: 791 EEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW 850
Query: 162 QKNAKAAQTKLAKGRQQTVQEAI-----EESRGLLQRRAQAAQEEQRRRCELISQLRALE 216
+ + AQ +L + R + +EA EE R + Q +E R+R + LR L+
Sbjct: 851 AREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ 910
Query: 217 TQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQ 276
Q ++ +L + ++P G+ S + A L + +K EE+R++ ++ ++ + Q
Sbjct: 911 QQQQQQ-QLAQM-KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQ 968
Query: 277 E-----LQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAA 331
LQ +Q + G + K L Q ++ QQ +++ +
Sbjct: 969 RELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1028
Query: 332 ERSRQAALLHVS 343
R+ + LH S
Sbjct: 1029 ARNNTHSNLHTS 1040
Score = 49.7 bits (117), Expect = 6e-06
Identities = 55/265 (20%), Positives = 120/265 (45%), Gaps = 23/265 (8%)
Query: 87 AKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLR 146
A ++ +QL ++ +L+ + E R+ ++ ++ + +Q+E++ + + +R
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 147 EDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC 206
E+ + E+ + Q+ + ++A RQ+ +E ++ L + + +EE+RR+
Sbjct: 782 EEELARRKQEEALRRQR-----EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 836
Query: 207 ELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-EEKRD 265
E + LR E + + + + Q E + + E RL +E ++RKE E +R
Sbjct: 837 EEL--LRKQEEEAAKWAREEEEAQ--RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
Query: 266 QIIQGKRTKSQE----LQNMVEQISLCRAAMGRSA-------ALRWEEKKALAAAPAAPS 314
+ + +R + QE LQ +Q L + + S+ + + L+ A
Sbjct: 893 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
Query: 315 QDERVQQLRRRISERAAERSRQAAL 339
++ER +QLR +R +R AL
Sbjct: 953 EEERERQLRE--EQRRQQRELMKAL 975
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 57.4 bits (137), Expect = 3e-08
Identities = 74/312 (23%), Positives = 140/312 (44%), Gaps = 30/312 (9%)
Query: 49 REGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSH 108
RE + ++ E+E +R ++L E Q++ + K REE+ A RR Q
Sbjct: 742 REAEMRAKREEEERKRQEEL---RRQQEEILRRQQEEERKRREEEELA---RRKQ----- 790
Query: 109 EEAVLA-RQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRK--ELV----EQVIEG 161
EEA+ R+ + +QR E++++Q + + + ERR E+ RK EL+ E+ +
Sbjct: 791 EEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW 850
Query: 162 QKNAKAAQTKLAKGRQQTVQEAI-----EESRGLLQRRAQAAQEEQRRRCELISQLRALE 216
+ + AQ +L + R + +EA EE R + Q +E R+R + LR L+
Sbjct: 851 AREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQ 910
Query: 217 TQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQ 276
Q ++ +L + ++P G+ S + A L + +K EE+R++ ++ ++ + Q
Sbjct: 911 QQQQQQ-QLAQM-KLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQ 968
Query: 277 E-----LQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAA 331
LQ +Q + G + K L Q ++ QQ +++ +
Sbjct: 969 RELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNR 1028
Query: 332 ERSRQAALLHVS 343
R+ + LH S
Sbjct: 1029 ARNNTHSNLHTS 1040
Score = 49.7 bits (117), Expect = 6e-06
Identities = 55/265 (20%), Positives = 120/265 (45%), Gaps = 23/265 (8%)
Query: 87 AKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLR 146
A ++ +QL ++ +L+ + E R+ ++ ++ + +Q+E++ + + +R
Sbjct: 722 ALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
Query: 147 EDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRC 206
E+ + E+ + Q+ + ++A RQ+ +E ++ L + + +EE+RR+
Sbjct: 782 EEELARRKQEEALRRQR-----EQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQ 836
Query: 207 ELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKE-EEKRD 265
E + LR E + + + + Q E + + E RL +E ++RKE E +R
Sbjct: 837 EEL--LRKQEEEAAKWAREEEEAQ--RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQ 892
Query: 266 QIIQGKRTKSQE----LQNMVEQISLCRAAMGRSA-------ALRWEEKKALAAAPAAPS 314
+ + +R + QE LQ +Q L + + S+ + + L+ A
Sbjct: 893 KELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKL 952
Query: 315 QDERVQQLRRRISERAAERSRQAAL 339
++ER +QLR +R +R AL
Sbjct: 953 EEERERQLRE--EQRRQQRELMKAL 975
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 57.0 bits (136), Expect = 3e-08
Identities = 64/288 (22%), Positives = 124/288 (43%), Gaps = 23/288 (7%)
Query: 48 LREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQ--KKMQAKDREEQLAASECRRLQGK 105
L E + + Q+ EL + + ++DG D FE Q +K DR EQ RLQ
Sbjct: 1903 LHEESRAREQLAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQEL 1962
Query: 106 LSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEG-QKN 164
+ ++ + + L+ K+ ++ + + + +LQ E+ ++E + E+V + QK
Sbjct: 1963 EAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQ 2022
Query: 165 AKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQ-AAQEEQRRRCELISQLRALETQPTRKG 223
KA + + + + ++ E++ L+ R Q A E+Q + +A++ + R
Sbjct: 2023 VKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHER-- 2080
Query: 224 KLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEE----------EKRDQIIQGKRT 273
D+ Q LE ++ +V R + E+Q R+ E +K +++ K
Sbjct: 2081 ---DVFQQEIQKLEQQLKVV---PRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQ 2134
Query: 274 KSQELQNMVEQISLCRAAMGR-SAALRWEEKKALAAAPAAPSQDERVQ 320
+++Q E+I + AL E++K A A P VQ
Sbjct: 2135 LQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQ 2182
Score = 39.7 bits (91), Expect = 0.006
Identities = 56/248 (22%), Positives = 102/248 (41%), Gaps = 11/248 (4%)
Query: 88 KDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQKE-QMAKLMLQRAERRLR 146
K + + L E RL+ K +E L +L E K+ E Q + K L R+E R
Sbjct: 3172 KAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEER-- 3229
Query: 147 EDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQ--EEQRR 204
D+ E ++ +E QK L + ++Q + E+ ++ QR AQ EEQ R
Sbjct: 3230 -DKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIES--QRMLYDAQLSEEQGR 3286
Query: 205 RCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLA---LLKENQRRKEE 261
EL L + + + +D + L+ + R L LLKE Q++ EE
Sbjct: 3287 NLELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEE 3346
Query: 262 EKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQ 321
+ + T+ +L ++ + + + L+ E++ +V+
Sbjct: 3347 KHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVED 3406
Query: 322 LRRRISER 329
L+R++ E+
Sbjct: 3407 LQRQLEEK 3414
Score = 35.8 bits (81), Expect = 0.083
Identities = 56/255 (21%), Positives = 109/255 (42%), Gaps = 37/255 (14%)
Query: 50 EGALYQR-----QVEQELQRVDKLVDGA-GDFSEFFEWQKKMQAKDREEQLAASECRRLQ 103
E A+ QR Q+ LQ+ + D +F E E +K+Q + +QL ASE R
Sbjct: 197 EAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQF--QQLQASETLRNS 254
Query: 104 GKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRK--ELVEQVIEG 161
S +L + + ++Q++E+Q L ED +K + Q+
Sbjct: 255 THSSTAADLLQAKQQILTHQQQLEEQDH-------------LLEDYQKKKEDFTMQISFL 301
Query: 162 QKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRA------- 214
Q+ K + + K + + +E I+E +++ EE+++ EL +L
Sbjct: 302 QEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGE 361
Query: 215 LETQPTRKGKLVD--LTQIPGYGLEGEMSIVELRERLALLKENQRR--KEEEKRDQIIQG 270
L+ Q +K + + ++ + S E+++ + ++E Q+R K+ + I+Q
Sbjct: 362 LQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQ- 420
Query: 271 KRTKSQELQNMVEQI 285
QE Q +EQ+
Sbjct: 421 --RMEQETQRKLEQL 433
Score = 35.4 bits (80), Expect = 0.11
Identities = 60/221 (27%), Positives = 93/221 (42%), Gaps = 19/221 (8%)
Query: 80 EWQKKM---QAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQE-NKQRVE-QQKEQMA 134
E QKKM Q+K + Q E R+ KL E L Q +MQE KQ +E ++K +
Sbjct: 3392 EGQKKMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRL--QGIMQEFQKQELEREEKRESR 3449
Query: 135 KLMLQRAER----RLREDRSRKELVEQVIEGQ-KNAKAAQTKLAKGRQQTVQEAIEESRG 189
+++ Q L DR+R +++Q IEG+ K + A+ G +E R
Sbjct: 3450 RILYQNLNEPTTWSLTSDRTRNWVLQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQ 3509
Query: 190 LLQRRAQAAQ-----EEQRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVE 244
LQ A Q +R + E + Q ++ L ++ G E E S+V
Sbjct: 3510 KLQCVASKLQVLPQKASERLQFETADDEDFIWVQENIDEIILQLQKLTGQQGE-EPSLVS 3568
Query: 245 LRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQI 285
L E R+ E I Q K+ +L+NMV ++
Sbjct: 3569 PSTSCGSLTERLLRQNAELTGHISQLTEEKN-DLRNMVMKL 3608
Score = 35.0 bits (79), Expect = 0.14
Identities = 50/253 (19%), Positives = 114/253 (45%), Gaps = 26/253 (10%)
Query: 55 QRQVEQELQRVDKLVDGAGDFSE--FFEWQKKMQAKDREEQLAASECRRLQGKLS----H 108
QR +++ + ++KL + + E +K A + + +L+ +LQ +
Sbjct: 2136 QRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEV--QLQAERDAIDRK 2193
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
E+ + + +++ ++ +E + E++ +L +Q E + +E +R + +EQ K K
Sbjct: 2194 EKEITNLEEQLEQFREELENKNEEVQQLHMQ-LEIQKKESTTRLQELEQE---NKLFKDD 2249
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQP--TRKGKLV 226
KL +++ + ++ L + AQ QE++ +L Q+ L+ Q T K++
Sbjct: 2250 MEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVI 2309
Query: 227 DLTQIPGYGLEGEMSIVELRERLALLKENQ---RRKEEEKRDQIIQGKRTKSQELQNMVE 283
+ E I +L ++ L +Q +R EE+ +Q+ + QEL N+ +
Sbjct: 2310 E---------EKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQ 2360
Query: 284 QISLCRAAMGRSA 296
+ S+ ++ A
Sbjct: 2361 KTSMNAHSLSEEA 2373
Score = 33.9 bits (76), Expect = 0.32
Identities = 67/290 (23%), Positives = 120/290 (41%), Gaps = 42/290 (14%)
Query: 47 ILREGALYQRQVE----------QELQRVDKLVDGAGDFSEFFEWQKKMQAKD--REEQL 94
IL E QRQ+E +++QR + + A S+ E K + + + E +
Sbjct: 519 ILEEKCALQRQLEDLVEELSFSREQIQRARQTI--AEQESKLNEAHKSLSTVEDLKAEIV 576
Query: 95 AASECRRLQGKLSHEEAVL---ARQSLMQENKQRVEQQKEQMAKLMLQRAERRL---RED 148
+ASE R+ + +L HE V + ++++ K V + + + L+R +L E+
Sbjct: 577 SASESRK-ELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEE 635
Query: 149 RSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCEL 208
K + IE + N + + L +Q + GL +Q + Q + L
Sbjct: 636 ELSKLKEDLEIEHRINIEKLKDNLGIHYKQQID-------GLQNEMSQKIETMQFEKDNL 688
Query: 209 ISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQII 268
I++ L + + KL DL Q S+V + L+ N+ +KE E Q
Sbjct: 689 ITKQNQLILEIS---KLKDLQQ----------SLVNSKSEEMTLQINELQKEIEILRQEE 735
Query: 269 QGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDER 318
+ K T QE+Q + + L M + +EK A A + +DE+
Sbjct: 736 KEKGTLEQEVQELQLKTELLEKQM-KEKENDLQEKFAQLEAENSILKDEK 784
Score = 32.7 bits (73), Expect = 0.71
Identities = 23/115 (20%), Positives = 55/115 (47%), Gaps = 3/115 (2%)
Query: 166 KAAQTKLAKGRQQTVQ-EAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGK 224
K + K+A +Q EA++E Q + E +R + ++QLR E
Sbjct: 2537 KIVEEKVAAALVSQIQLEAVQEYAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISAL 2596
Query: 225 LVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEE--KRDQIIQGKRTKSQE 277
+ ++++ +E S++ +E++ + ++N KE++ + ++++G K +E
Sbjct: 2597 TLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQRE 2651
Score = 31.6 bits (70), Expect = 1.6
Identities = 49/221 (22%), Positives = 86/221 (38%), Gaps = 31/221 (14%)
Query: 109 EEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQKNAKAA 168
EE Q L++ E E +LML + R E + + ++AK
Sbjct: 1816 EEGTELSQRLVRSGFAGTEIDPEN-EELMLNISSRLQAAVEKLLEAISETSSQLEHAKVT 1874
Query: 169 QTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRKGKLVDL 228
QT+L + + QEA E + QEE R R L + RA E K +
Sbjct: 1875 QTELMRESFRQKQEATESLK---------CQEELRER--LHEESRAREQLAVELSKAEGV 1923
Query: 229 TQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLC 288
I GY E + +++E+ ++ ++ +Q + + QEL+ +QI
Sbjct: 1924 --IDGYADEKTLFERQIQEKTDII---------DRLEQELLCASNRLQELEAEQQQIQEE 1972
Query: 289 RAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISER 329
R + R +K A A P + + +Q+ + + E+
Sbjct: 1973 RELLSR--------QKEAMKAEAGPVEQQLLQETEKLMKEK 2005
Score = 29.6 bits (65), Expect = 6.0
Identities = 33/181 (18%), Positives = 76/181 (41%), Gaps = 19/181 (10%)
Query: 55 QRQVEQELQRVDKLVDGAGDFSEFFEWQKK-----MQAKDREEQLAASECRRLQGKLSHE 109
+ Q+EQ + ++ + E QKK +Q ++E +L + +L +
Sbjct: 2201 EEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKES 2260
Query: 110 EAVLARQS---------LMQENKQRVEQQKEQMAKLMLQ---RAERRLREDRSRKELVEQ 157
+A+ + ++QE + ++Q EQ+ KL Q + ++ E+++ EL+
Sbjct: 2261 DAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKN--ELIRD 2318
Query: 158 VIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALET 217
+ + + Q + + R++ +++ E L Q A Q+ L + +L+
Sbjct: 2319 LETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKH 2378
Query: 218 Q 218
Q
Sbjct: 2379 Q 2379
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 56.2 bits (134), Expect = 6e-08
Identities = 60/298 (20%), Positives = 130/298 (43%), Gaps = 17/298 (5%)
Query: 48 LREGALYQRQVEQELQRVDKLV---DGAGDFSEFFEWQKKMQAKDREEQLAASE--CRRL 102
+RE R+ E++++R ++++ + E W+K+ + + EE + E R L
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382
Query: 103 QGKLSHEEAVLARQSLMQENKQRVEQQKEQMAKLMLQRAERRLREDRSRKELVEQVIEGQ 162
+ K+ +E + ++ QE ++ EQ+K Q + + R E ++RE + E+ + Q
Sbjct: 383 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442
Query: 163 KNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRK 222
+ Q K+ + ++ QE + Q QEE R+ E + + + Q +
Sbjct: 443 EEKIHEQEKIREEEKRQEQEEMWR-----QEEKIREQEEIWRQKEKMHEQEKIRKQEEKV 497
Query: 223 GKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQNMV 282
+ + + E I E E++ +E R +EE+ R+Q + R + + +Q
Sbjct: 498 WRQEEKMH------DQEEKIREQEEKMWRQEEKIREQEEKIREQ-EEKIREQEEMMQEQE 550
Query: 283 EQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSRQAALL 340
E++ M +R +E+K Q E++++ +I E+ + Q ++
Sbjct: 551 EKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM 608
Score = 50.1 bits (118), Expect = 4e-06
Identities = 66/368 (17%), Positives = 150/368 (40%), Gaps = 57/368 (15%)
Query: 9 VQGSKQQLRLQFPPRIRKTPKLTFYRPDNIL-------------VKLNTTAILREGALYQ 55
V+ K +++L RK + P L V A + E L+
Sbjct: 233 VESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 292
Query: 56 R---QVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAV 112
R Q E+++ R ++ + EW++K+Q ++ + + + R + K+ +E +
Sbjct: 293 RLNQQQEEKMWRQEEKIQ---------EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM 343
Query: 113 L-ARQSLMQENKQRVEQQKEQMAKL--MLQRAERRLRE------------DRSRKELVEQ 157
+ ++ M+ ++ + +++E+M +L M+ E ++RE ++ K E+
Sbjct: 344 MWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE 403
Query: 158 VIEGQKNAKAAQTKL----AKGRQQ------------TVQEAIEESRGLLQRRAQAAQEE 201
I Q+ + + K+ K R+Q +E I E + + + QEE
Sbjct: 404 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 463
Query: 202 QRRRCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEE 261
R+ E I + + Q + + + + E + + E++ +E R+EE
Sbjct: 464 MWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE 523
Query: 262 EKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQ 321
+ R+Q + R + ++++ E + MG E++K Q+E++++
Sbjct: 524 KIREQ-EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIRE 582
Query: 322 LRRRISER 329
+ +I E+
Sbjct: 583 QKEKIREQ 590
Score = 48.5 bits (114), Expect = 1e-05
Identities = 45/243 (18%), Positives = 113/243 (46%), Gaps = 16/243 (6%)
Query: 48 LREGALYQRQVEQELQRVDKLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKL- 106
+RE + E+++ +K+ + + W+++ + +++EE E Q K+
Sbjct: 432 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Query: 107 SHEEAVLARQSLMQENKQRVEQQKEQMAKL--MLQRAERRLREDRSRKELVEQVIEGQKN 164
EE V ++ M + ++++ +Q+E+M + ++ E ++RE + E++++ Q+
Sbjct: 492 KQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE 551
Query: 165 AKAAQTKLAKGRQQT--VQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPTRK 222
Q + + +++ +E I E ++ + + +E++ + E ++R E +
Sbjct: 552 KMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQ 611
Query: 223 GKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQII--QGKRTKSQELQN 280
+ + E E + E E++ +E RR+EE+ +Q + + + K QE Q
Sbjct: 612 EEKM---------WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
Query: 281 MVE 283
+E
Sbjct: 663 HLE 665
Score = 43.1 bits (100), Expect = 5e-04
Identities = 65/366 (17%), Positives = 154/366 (42%), Gaps = 62/366 (16%)
Query: 7 ERVQGSKQQLRLQFPPRIRKTPKLTFYRPDNILVKLNTTAILREGALYQRQVEQELQRVD 66
E++Q ++++R Q +IR+ + R + ++ + +E ++++ E++++R++
Sbjct: 314 EKIQEQEEKIREQ-EEKIREQEE-KMRRQEEMMWEKEEKMRRQEEMMWEK--EEKMRRLE 369
Query: 67 KLVDGAGDFSEFFEWQKKMQAKDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRV 126
+++ W+K+ + ++ EE++ E R Q + EE + Q QE + ++
Sbjct: 370 EMM-----------WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 418
Query: 127 EQQKEQMA----------KLMLQRAER-----RLREDRSRKELVE-----------QVIE 160
+Q+E++ K M ++ E+ ++RE+ R+E E + I
Sbjct: 419 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 478
Query: 161 GQKNAKAAQTKLAKGRQQT---------VQEAIEESRGLLQRRAQAAQEEQRRRCELISQ 211
QK Q K+ K ++ +E I E + R+ + +E++ + E +
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538
Query: 212 LRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGK 271
+R E + + + GE + +E + R++EEK + +
Sbjct: 539 IREQEEMMQEQEEKM-----------GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 272 RTKSQELQNMVEQISLCRAAMGRSAALRWE-EKKALAAAPAAPSQDERVQQLRRRISERA 330
R + +++ E+I M WE E+K Q+E++++ ++ E+
Sbjct: 588 REQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 647
Query: 331 AERSRQ 336
+Q
Sbjct: 648 VRLRQQ 653
Score = 33.9 bits (76), Expect = 0.32
Identities = 40/202 (19%), Positives = 85/202 (42%), Gaps = 18/202 (8%)
Query: 142 ERRLREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEAIEESRGLLQRRAQAAQEE 201
E+ L ++K+ ++ IE + A + L R E ++E LQ + Q + E
Sbjct: 178 EQALSAVATQKKKADRYIEELTKERDALS-LELYRNTITDEELKEKNAKLQEKLQLVESE 236
Query: 202 QRR-------------RCELISQLRALETQPTRKGKLVDLTQIPGYGLEGEMSIVELRER 248
+ R +L+ + L+ + GK + Q L+ ++ EL R
Sbjct: 237 KSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKEL---QSVSAKLQAQVEENELWNR 293
Query: 249 LALLKENQRRKEEEKRDQIIQGKRTKSQELQNMVEQISLCRAAMGRSAALRWE-EKKALA 307
L +E + ++EEK + + + + ++++ E+I M R + WE E+K
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 308 AAPAAPSQDERVQQLRRRISER 329
++E++++L + E+
Sbjct: 354 QEEMMWEKEEKMRRLEEMMWEK 375
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 55.8 bits (133), Expect = 8e-08
Identities = 43/144 (29%), Positives = 75/144 (52%), Gaps = 18/144 (12%)
Query: 79 FEWQKKMQAKDREEQLAASECRR----LQGKLSHEEAVLARQSLMQENKQRVEQQKEQMA 134
FE Q+K++ ++ EE+L E R L K EE + + +E +RVE+ K M
Sbjct: 110 FERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIME 169
Query: 135 KLMLQRAER-----------RLREDRSRKELVEQVI-EGQKNAKAAQTKLAKGRQQTVQE 182
K +L+ ER R E+R+++E +E+++ E + AQ KLA+ + + V+E
Sbjct: 170 KQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEE 229
Query: 183 --AIEESRGLLQRRAQAAQEEQRR 204
I E R L++ Q Q+E+++
Sbjct: 230 QRKIHEERMKLEQERQRQQKEEQK 253
Score = 45.8 bits (107), Expect = 8e-05
Identities = 50/203 (24%), Positives = 100/203 (49%), Gaps = 31/203 (15%)
Query: 88 KDREEQLAASECRRLQGKLSHEEAVLARQSLMQENKQRVEQQK---EQMAKLMLQRAERR 144
++R+ + A+S R+ V R SL ++ K+ E++K E+ K+ Q E +
Sbjct: 68 RERDRERASSPPDRID---IFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEK 124
Query: 145 LREDRSRKELVEQVIEGQKNAKAAQTKLAKGRQQTVQEA---IEESRGLLQRRAQAAQEE 201
L E+ + + + E V AK + +L K + + +E +EE++ +++++ E
Sbjct: 125 LIEEETARRVEELV------AKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELER 178
Query: 202 QRRRCELISQLRALETQPTRKGKLVDLTQIPGYGL--------EGEMSIVELR-----ER 248
QR+ EL +Q E + ++ +L + + + E ++ IVE + ER
Sbjct: 179 QRQ-AELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEER 237
Query: 249 LALLKENQRRKEEEKRDQIIQGK 271
+ L +E QR+++EE++ II GK
Sbjct: 238 MKLEQERQRQQKEEQK--IILGK 258
Score = 38.1 bits (87), Expect = 0.017
Identities = 35/175 (20%), Positives = 81/175 (46%), Gaps = 16/175 (9%)
Query: 162 QKNAKAAQTKLAK-GRQQTVQEAIEESRGLLQRRAQAAQEEQRRRCELISQLRALETQPT 220
+ ++++ TK +K ++++ + + +++R+++ + ++ RR E S+ R+ T +
Sbjct: 7 RSSSRSKHTKSSKHNKKRSRSRSRSRDKERVRKRSKSRESKRNRRRESRSRSRSTNTAVS 66
Query: 221 RKGKLVDLTQIPGYGLEGEMSIVELRERLALLKENQRRKEEEKRDQIIQGKRTKSQELQN 280
R+ + + P ++ V R L E Q+R+EEEK+ + + ++ + QE++
Sbjct: 67 RRERDRERASSPPDRIDIFGRTVSKRSSL---DEKQKREEEEKKAEFERQRKIRQQEIEE 123
Query: 281 MVEQISLCRAAMGRSAALRWEEKKALAAAPAAPSQDERVQQLRRRISERAAERSR 335
+ + A R EE L A ++R ++ R + R E R
Sbjct: 124 KL---------IEEETARRVEE---LVAKRVEEELEKRKDEIEREVLRRVEEAKR 166
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,763,928
Number of Sequences: 37866
Number of extensions: 868406
Number of successful extensions: 11251
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 907
Number of HSP's that attempted gapping in prelim test: 7105
Number of HSP's gapped (non-prelim): 3053
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.