Search of human proteins with 169164530

Search of human proteins with 169164530

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169164530 PREDICTED: similar to hCG1818432 [Homo sapiens]
         (541 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169164530 PREDICTED: similar to hCG1818432 [Homo sapiens]         1115   0.0  
gi|169164924 PREDICTED: similar to hCG1818432 [Homo sapiens]         1113   0.0  
gi|169163549 PREDICTED: hypothetical protein LOC646960 [Homo sap...  1113   0.0  
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           157   2e-38
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   147   2e-35
gi|110815798 ovochymase 1 [Homo sapiens]                              145   7e-35
gi|145275213 coagulation factor XII precursor [Homo sapiens]          145   1e-34
gi|11415040 matriptase [Homo sapiens]                                 143   3e-34
gi|117956391 protease, serine, 33 [Homo sapiens]                      142   1e-33
gi|223942069 enterokinase precursor [Homo sapiens]                    139   5e-33
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   135   7e-32
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   135   7e-32
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           133   4e-31
gi|33695155 hepsin [Homo sapiens]                                     132   1e-30
gi|4504481 hepsin [Homo sapiens]                                      132   1e-30
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          130   3e-30
gi|194018492 transmembrane protease, serine 11F [Homo sapiens]        130   4e-30
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          127   3e-29
gi|4506153 prostasin preproprotein [Homo sapiens]                     125   8e-29
gi|32698940 transmembrane protease, serine 12 [Homo sapiens]          123   5e-28
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             122   6e-28
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]           122   8e-28
gi|40254871 transmembrane protease, serine 11E [Homo sapiens]         122   1e-27
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]       122   1e-27
gi|148613878 acrosin precursor [Homo sapiens]                         121   2e-27
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      120   2e-27
gi|118498341 chymotrypsin B1 [Homo sapiens]                           120   3e-27
gi|4505881 plasminogen [Homo sapiens]                                 120   4e-27
gi|4504383 HGF activator preproprotein [Homo sapiens]                 119   5e-27
gi|222831592 transmembrane protease, serine 7 [Homo sapiens]          119   7e-27

>gi|169164530 PREDICTED: similar to hCG1818432 [Homo sapiens]
          Length = 541

 Score = 1115 bits (2885), Expect = 0.0
 Identities = 541/541 (100%), Positives = 541/541 (100%)

Query: 1   MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60
           MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG
Sbjct: 1   MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60

Query: 61  GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120
           GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF
Sbjct: 61  GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120

Query: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180
           DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV
Sbjct: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180

Query: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240
           REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL
Sbjct: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240

Query: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300
           FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA
Sbjct: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300

Query: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360
           ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR
Sbjct: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360

Query: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420
           RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK
Sbjct: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420

Query: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480
           LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL
Sbjct: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480

Query: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPAARQ 540
           EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPAARQ
Sbjct: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPAARQ 540

Query: 541 P 541
           P
Sbjct: 541 P 541


>gi|169164924 PREDICTED: similar to hCG1818432 [Homo sapiens]
          Length = 541

 Score = 1113 bits (2880), Expect = 0.0
 Identities = 540/541 (99%), Positives = 540/541 (99%)

Query: 1   MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60
           MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG
Sbjct: 1   MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60

Query: 61  GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120
           GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF
Sbjct: 61  GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120

Query: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180
           DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV
Sbjct: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180

Query: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240
           REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL
Sbjct: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240

Query: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300
           FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA
Sbjct: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300

Query: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360
           ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR
Sbjct: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360

Query: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420
           RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK
Sbjct: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420

Query: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480
           LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL
Sbjct: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480

Query: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPAARQ 540
           EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVP ARQ
Sbjct: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQ 540

Query: 541 P 541
           P
Sbjct: 541 P 541


>gi|169163549 PREDICTED: hypothetical protein LOC646960 [Homo
           sapiens]
          Length = 541

 Score = 1113 bits (2880), Expect = 0.0
 Identities = 540/541 (99%), Positives = 540/541 (99%)

Query: 1   MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60
           MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG
Sbjct: 1   MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60

Query: 61  GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120
           GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF
Sbjct: 61  GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120

Query: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180
           DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV
Sbjct: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180

Query: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240
           REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL
Sbjct: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240

Query: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300
           FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA
Sbjct: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300

Query: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360
           ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR
Sbjct: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360

Query: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420
           RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK
Sbjct: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420

Query: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480
           LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL
Sbjct: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480

Query: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPAARQ 540
           EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVP ARQ
Sbjct: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQ 540

Query: 541 P 541
           P
Sbjct: 541 P 541


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  157 bits (398), Expect = 2e-38
 Identities = 83/171 (48%), Positives = 103/171 (60%), Gaps = 3/171 (1%)

Query: 103  GEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTAC 162
            G + +   V RI  HP ++  T   D+AL++L  PV      RP+CLP+    PP GT C
Sbjct: 890  GAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRC 949

Query: 163  AIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGD 222
             I GWG++ E G  A  +++A V LLS  TCRR   P    S MLCAG+  GGVDSC GD
Sbjct: 950  VITGWGSVREGGSMARQLQKAAVRLLSEQTCRR-FYPVQISSRMLCAGFPQGGVDSCSGD 1008

Query: 223  SGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQM 273
            +GGPL C EP    R VL GVTSWG GCG P  PGVYTRVA  + W+ + +
Sbjct: 1009 AGGPLACREPS--GRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHI 1057



 Score =  134 bits (338), Expect = 2e-31
 Identities = 78/184 (42%), Positives = 102/184 (55%), Gaps = 6/184 (3%)

Query: 103 GEQAEEV--PVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGT 160
           G +A  V   V +I+ HP ++  T   D+A+++L +P+  G   +PVCLP      P   
Sbjct: 265 GSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSK 324

Query: 161 ACAIAGWGALFEDG-PEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSC 219
            C I+GWG L ED   + E +++A V LL    C    G  L    M+CAGYL G VDSC
Sbjct: 325 KCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLT-DRMVCAGYLDGKVDSC 383

Query: 220 QGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSS 279
           QGDSGGPL C EP    R  L G+ SWG GC E  +PGVY RV   +DW+ E  + AS  
Sbjct: 384 QGDSGGPLVCEEPS--GRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASMP 441

Query: 280 REPS 283
             P+
Sbjct: 442 LAPT 445



 Score =  130 bits (328), Expect = 2e-30
 Identities = 76/195 (38%), Positives = 108/195 (55%), Gaps = 7/195 (3%)

Query: 103 GEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTAC 162
           G    ++ + R++ HP ++P     DLA+++L +P++     +PVCLP   Q+ P G  C
Sbjct: 567 GGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKC 626

Query: 163 AIAGWGALFE-DGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQG 221
            I+GWG   E +  + E +++A V ++   TC       L    M+CAG+L G VDSCQG
Sbjct: 627 MISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSL-TDRMICAGFLEGKVDSCQG 685

Query: 222 DSGGPLTCSE-PGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAAS-SS 279
           DSGGPL C E PG      L G+ SWG GC +  KPGVYTR+   K W+ E MS+     
Sbjct: 686 DSGGPLACEEAPGV---FYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPM 742

Query: 280 REPSCRELLAWDPPQ 294
             PS   +LA   P+
Sbjct: 743 SPPSTTRMLATTSPR 757


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  147 bits (371), Expect = 2e-35
 Identities = 79/165 (47%), Positives = 99/165 (60%), Gaps = 5/165 (3%)

Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
           V +I+ H K+ P+   ND+AL++L  P++     +PVCLP   +  P G  C  +GWGA 
Sbjct: 287 VEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGAT 346

Query: 171 FEDGPEAEAV-REARVPLLSTDTCR-RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLT 228
            +   +A  V   A VPL+S   C  R +  G+   +MLCAGYL GGVDSCQGDSGGPL 
Sbjct: 347 EDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLV 406

Query: 229 CSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQM 273
           C E   R    L G TS+G GC E  KPGVYTRV  F DW+ EQM
Sbjct: 407 CQE---RRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQM 448


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  145 bits (367), Expect = 7e-35
 Identities = 83/222 (37%), Positives = 120/222 (54%), Gaps = 12/222 (5%)

Query: 89  NELLWTVTLAEGSRG--EQAEEVP-VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSAR 145
           N L WT+   +  R   E  E+V     I+ H  F+  ++ +D+AL+QL +P+      R
Sbjct: 622 NPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVR 681

Query: 146 PVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRR---ALGPGLR 202
           PVCLP   +   +   CA+ GWG++  DG  A  +++ +V +L  + C     +  PG  
Sbjct: 682 PVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGI 741

Query: 203 PSTMLCAGYLAGG-VDSCQGDSGGPLTC-SEPGPRPREVLFGVTSWGDGCGEPGKPGVYT 260
              M+CAG+ A G  D CQGDSGGPL C  E GP    VL+G+ SWG GC +P KPGV+ 
Sbjct: 742 TEKMICAGFAASGEKDFCQGDSGGPLVCRHENGP---FVLYGIVSWGAGCVQPWKPGVFA 798

Query: 261 RVAVFKDWLQEQMSA-ASSSREPSCRELLAWDPPQELQADAA 301
           RV +F DW+Q +++  AS      C+ L    PP     D+A
Sbjct: 799 RVMIFLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSA 840



 Score =  110 bits (276), Expect = 3e-24
 Identities = 63/206 (30%), Positives = 105/206 (50%), Gaps = 19/206 (9%)

Query: 94  TVTLAEGS---RGEQAEEVPVNRILPHPKFDPRTFHN-DLALVQLWTPVSPGGSARPVCL 149
           TVT  E S   + +Q + +PV++I+ HP+++ R + + D+AL+ L   V  G + +P+CL
Sbjct: 101 TVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICL 160

Query: 150 PQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPS---TM 206
           P    +   G  C  +GWG + +    +  ++E  +P++    C   L     P    TM
Sbjct: 161 PDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTM 220

Query: 207 LCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKP---------- 256
           LCAG+   G+D+CQGDSGGPL C   G     +L G+TSW  GC     P          
Sbjct: 221 LCAGFPDWGMDACQGDSGGPLVCRRGG--GIWILAGITSWVAGCAGGSVPVRNNHVKASL 278

Query: 257 GVYTRVAVFKDWLQEQMSAASSSREP 282
           G++++V+   D++ + +       +P
Sbjct: 279 GIFSKVSELMDFITQNLFTGLDRGQP 304


>gi|145275213 coagulation factor XII precursor [Homo sapiens]
          Length = 615

 Score =  145 bits (365), Expect = 1e-34
 Identities = 104/282 (36%), Positives = 137/282 (48%), Gaps = 25/282 (8%)

Query: 12  PSSWFAHGHPLYTRLPPSALQ-GP--CGER-RPSTANVTRAHGRIVE-KARHAG-----G 61
           P S      P     PPS  + GP  CG+R R S +++TR  G +V  +  H        
Sbjct: 333 PQSQTPGALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAALYW 392

Query: 62  GAGSPRGLRGVPLSFLRLS-CRSTRSAPNELLWTVTLAEGSRG---EQAEEVPVNRILPH 117
           G     G    P   L  + C   R AP +L  TV L +  R    E  + + V     H
Sbjct: 393 GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDL--TVVLGQERRNHSCEPCQTLAVRSYRLH 450

Query: 118 PKFDPRTFHNDLALVQLWTPVSPGGS-----ARPVCLPQEPQEPPAGTACAIAGWGALFE 172
             F P ++ +DLAL++L        +      +PVCLP     P   T C +AGWG  FE
Sbjct: 451 EAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFE 510

Query: 173 DGPE-AEAVREARVPLLSTDTCRR--ALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
              E A  ++EA+VP LS + C      G  + P  MLCAG+L GG D+CQGDSGGPL C
Sbjct: 511 GAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPG-MLCAGFLEGGTDACQGDSGGPLVC 569

Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQE 271
            +     R  L G+ SWG GCG+  KPGVYT VA +  W++E
Sbjct: 570 EDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIRE 611


>gi|11415040 matriptase [Homo sapiens]
          Length = 855

 Score =  143 bits (361), Expect = 3e-34
 Identities = 78/197 (39%), Positives = 108/197 (54%), Gaps = 19/197 (9%)

Query: 75  SFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQL 134
           +FL L  +S RSAP                  +E  + RI+ HP F+  TF  D+AL++L
Sbjct: 674 AFLGLHDQSQRSAPG----------------VQERRLKRIISHPFFNDFTFDYDIALLEL 717

Query: 135 WTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCR 194
             P       RP+CLP      PAG A  + GWG     G  A  +++  + +++  TC 
Sbjct: 718 EKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCE 777

Query: 195 RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPG 254
             L   + P  M+C G+L+GGVDSCQGDSGGPL+  E   R  +   GV SWGDGC +  
Sbjct: 778 NLLPQQITP-RMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQA--GVVSWGDGCAQRN 834

Query: 255 KPGVYTRVAVFKDWLQE 271
           KPGVYTR+ +F+DW++E
Sbjct: 835 KPGVYTRLPLFRDWIKE 851


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  142 bits (357), Expect = 1e-33
 Identities = 99/266 (37%), Positives = 123/266 (46%), Gaps = 40/266 (15%)

Query: 35  CGERRPSTANVTRAHGR---------IVEKARHAGGGAGSPRGLRGVPLSFLRLSCRSTR 85
           CG+ R S+  V    GR         I  +  H  GG+     L           C   R
Sbjct: 28  CGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGS-----LIAPQWVLTAAHCFPRR 82

Query: 86  SAPNELLWTV-TLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSA 144
           + P E    +  L  GS   +   VPV R+L  P +       DLAL+QL  PV      
Sbjct: 83  ALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARV 142

Query: 145 RPVCLPQEPQEPPAGTACAIAGWGALFEDG---PEAEAVREARVPLLSTDTC-------- 193
           +PVCLP     PP GT C + GWG+L   G   PE   ++  RVPLL + TC        
Sbjct: 143 QPVCLPVPGARPPPGTPCRVTGWGSL-RPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGA 201

Query: 194 -----RRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGD 248
                 R + PG      LCAGY  G  D+CQGDSGGPLTC + G     VL GV SWG 
Sbjct: 202 DVPQAERIVLPG-----SLCAGYPQGHKDACQGDSGGPLTCLQSG---SWVLVGVVSWGK 253

Query: 249 GCGEPGKPGVYTRVAVFKDWLQEQMS 274
           GC  P +PGVYT VA +  W+Q ++S
Sbjct: 254 GCALPNRPGVYTSVATYSPWIQARVS 279


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score =  139 bits (351), Expect = 5e-33
 Identities = 70/160 (43%), Positives = 98/160 (61%), Gaps = 3/160 (1%)

Query: 111  VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
            ++ I+ +P ++ R   ND+A++ L   V+     +P+CLP+E Q  P G  C+IAGWG +
Sbjct: 859  IDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTV 918

Query: 171  FEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCS 230
               G  A  ++EA VPLLS + C++ +        M+CAGY  GG+DSCQGDSGGPL C 
Sbjct: 919  VYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQ 978

Query: 231  EPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQ 270
            E     R  L GVTS+G  C  P +PGVY RV+ F +W+Q
Sbjct: 979  E---NNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQ 1015


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  135 bits (341), Expect = 7e-32
 Identities = 71/166 (42%), Positives = 95/166 (57%), Gaps = 4/166 (2%)

Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
           V +++ HP +D +T +ND+AL++L  P++     +PVCLP           C I+GWGA 
Sbjct: 365 VEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGAT 424

Query: 171 FEDGPEAEAVREARVPLLSTDTCR-RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
            E G  +E +  A+V L+ T  C  R +   L    M+CAG+L G VDSCQGDSGGPL  
Sbjct: 425 EEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVT 484

Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSA 275
           S+        L G TSWG GC +  +PGVY  V VF DW+  QM A
Sbjct: 485 SK---NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRA 527


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  135 bits (341), Expect = 7e-32
 Identities = 71/166 (42%), Positives = 95/166 (57%), Gaps = 4/166 (2%)

Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
           V +++ HP +D +T +ND+AL++L  P++     +PVCLP           C I+GWGA 
Sbjct: 328 VEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGAT 387

Query: 171 FEDGPEAEAVREARVPLLSTDTCR-RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
            E G  +E +  A+V L+ T  C  R +   L    M+CAG+L G VDSCQGDSGGPL  
Sbjct: 388 EEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVT 447

Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSA 275
           S+        L G TSWG GC +  +PGVY  V VF DW+  QM A
Sbjct: 448 SK---NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRA 490


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  133 bits (335), Expect = 4e-31
 Identities = 79/194 (40%), Positives = 100/194 (51%), Gaps = 6/194 (3%)

Query: 81  CRSTRSAPNELLWTVTLA---EGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTP 137
           C    S  + +LWTV L    + SR        V+R+L HP  +  +   D+AL+QL  P
Sbjct: 618 CFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHP 677

Query: 138 VSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRAL 197
           V    + RPVCLP        G  C I GWGAL E GP + A+++  V L+  D C    
Sbjct: 678 VVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVY 737

Query: 198 GPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPG 257
              + P  MLCAGY  G  D+CQGDSGGPL C       R  L G+ SWG GCG P   G
Sbjct: 738 RYQVTP-RMLCAGYRKGKKDACQGDSGGPLVCK--ALSGRWFLAGLVSWGLGCGRPNYFG 794

Query: 258 VYTRVAVFKDWLQE 271
           VYTR+     W+Q+
Sbjct: 795 VYTRITGVISWIQQ 808


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  132 bits (331), Expect = 1e-30
 Identities = 68/156 (43%), Positives = 92/156 (58%), Gaps = 4/156 (2%)

Query: 127 NDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVP 186
           ND+ALV L +P+      +PVCLP   Q    G  C + GWG     G +A  ++EARVP
Sbjct: 256 NDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVP 315

Query: 187 LLSTDTCRRA--LGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPR-PREVLFGV 243
           ++S D C  A   G  ++P  M CAGY  GG+D+CQGDSGGP  C +   R PR  L G+
Sbjct: 316 IISNDVCNGADFYGNQIKPK-MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGI 374

Query: 244 TSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSS 279
            SWG GC    KPGVYT+V+ F++W+ + +   S +
Sbjct: 375 VSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEA 410


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  132 bits (331), Expect = 1e-30
 Identities = 68/156 (43%), Positives = 92/156 (58%), Gaps = 4/156 (2%)

Query: 127 NDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVP 186
           ND+ALV L +P+      +PVCLP   Q    G  C + GWG     G +A  ++EARVP
Sbjct: 256 NDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVP 315

Query: 187 LLSTDTCRRA--LGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPR-PREVLFGV 243
           ++S D C  A   G  ++P  M CAGY  GG+D+CQGDSGGP  C +   R PR  L G+
Sbjct: 316 IISNDVCNGADFYGNQIKPK-MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGI 374

Query: 244 TSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSS 279
            SWG GC    KPGVYT+V+ F++W+ + +   S +
Sbjct: 375 VSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEA 410


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  130 bits (327), Expect = 3e-30
 Identities = 69/163 (42%), Positives = 94/163 (57%), Gaps = 5/163 (3%)

Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
           V RI+PHP +  +    D+AL++L T ++   +   VCLP + Q  P G+ C ++GWG  
Sbjct: 291 VERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHT 350

Query: 171 FEDGP-EAEAVREARVPLLSTDTCRRA-LGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLT 228
                  ++ +++  VPL ST  C  + +  G     MLCAGYL G  D+CQGDSGGPL 
Sbjct: 351 HPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLV 410

Query: 229 CSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQE 271
           C + G   R  L GV SWG GC EP  PGVY +VA F DW+ +
Sbjct: 411 CPD-GDTWR--LVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHD 450


>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
          Length = 438

 Score =  130 bits (326), Expect = 4e-30
 Identities = 66/160 (41%), Positives = 93/160 (58%), Gaps = 4/160 (2%)

Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
           V +I+ H  +   T  ND+ALVQL T V      + VCLP    + P  T+  + G+G++
Sbjct: 276 VRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSI 335

Query: 171 FEDGPEAEAVREARVPLLSTDTC-RRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
            +DGP    +R+ARV  +STD C R+ +  GL    MLCAG++ G +D+C+GDSGGPL  
Sbjct: 336 VDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVY 395

Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWL 269
                     + G+ SWG  C  P KPGVYTRV  ++DW+
Sbjct: 396 DN---HDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 3e-29
 Identities = 69/163 (42%), Positives = 88/163 (53%), Gaps = 3/163 (1%)

Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
           V  IL H  +   T  ND+ALV+L   V+       VCLP   Q  P G+   + GWGA 
Sbjct: 255 VRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQ 314

Query: 171 FEDGPEAEAVREARVPLLSTDTCRRALG-PGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
              G     +R+ +V ++S D C       G   S MLCAG   GGVD+CQGDSGGPL  
Sbjct: 315 EYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLV- 373

Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQ 272
            +   R    + G+ SWGD CG P KPGVYTRV  + DW+++Q
Sbjct: 374 -QEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQ 415


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  125 bits (315), Expect = 8e-29
 Identities = 67/195 (34%), Positives = 98/195 (50%), Gaps = 12/195 (6%)

Query: 101 SRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGT 160
           S  E A+   +  I+PHP +       D+AL+QL  P++     RP+CLP      P G 
Sbjct: 107 SYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGL 166

Query: 161 ACAIAGWGALFEDGP--EAEAVREARVPLLSTDTCRRALGPGLRP-------STMLCAGY 211
            C + GWG +         + +++  VPL+S +TC        +P         M+CAGY
Sbjct: 167 HCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGY 226

Query: 212 LAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQE 271
           + GG D+CQGDSGGPL+C   G      L G+ SWGD CG   +PGVYT  + +  W+Q 
Sbjct: 227 VEGGKDACQGDSGGPLSCPVEG---LWYLTGIVSWGDACGARNRPGVYTLASSYASWIQS 283

Query: 272 QMSAASSSREPSCRE 286
           +++       P  +E
Sbjct: 284 KVTELQPRVVPQTQE 298


>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
          Length = 348

 Score =  123 bits (308), Expect = 5e-28
 Identities = 71/201 (35%), Positives = 107/201 (53%), Gaps = 8/201 (3%)

Query: 84  TRSAPNELLWTVTLAEGS---RGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSP 140
           T+ A + L+WT  +   +   R    +++ +  I+ HP F   ++ ND+AL  L   V  
Sbjct: 124 TKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRY 183

Query: 141 GGSARPVCLPQEP-QEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCR--RAL 197
               +P+CLP +  Q     T C I+GWG   E+G     +++A V  +S + C   R+ 
Sbjct: 184 NDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSY 243

Query: 198 GPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPG 257
           G G+ P+T  CAG   G  D+C+GDSGGPL C  P  + R  + G+TS+G GCG  G PG
Sbjct: 244 G-GIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYK-RFFVMGITSYGHGCGRRGFPG 301

Query: 258 VYTRVAVFKDWLQEQMSAASS 278
           VY   + ++ WL E    AS+
Sbjct: 302 VYIGPSFYQKWLTEHFFHAST 322


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  122 bits (307), Expect = 6e-28
 Identities = 57/171 (33%), Positives = 93/171 (54%), Gaps = 3/171 (1%)

Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
           +  I+ H  +     ++D+AL++L  P++     +P+CLP +       T C + GWG  
Sbjct: 466 IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFS 525

Query: 171 FEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCS 230
            E G     +++  +PL++ + C++          M+CAGY  GG D+C+GDSGGPL C 
Sbjct: 526 KEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCK 585

Query: 231 EPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSRE 281
             G      L G+TSWG+GC    +PGVYT+VA + DW+ E+  ++    +
Sbjct: 586 HNG---MWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQ 633


>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
          Length = 247

 Score =  122 bits (306), Expect = 8e-28
 Identities = 64/166 (38%), Positives = 92/166 (55%), Gaps = 11/166 (6%)

Query: 113 RILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFE 172
           +I+ HP++D +T +ND+ L++L +          + LP  P  P  GT C I+GWG    
Sbjct: 92  KIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAP--PATGTKCLISGWGNTAS 149

Query: 173 DGPE-AEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSE 231
            G +  + ++    P+LS   C  +  PG   S M C G+L GG DSCQGDSGGP+ C+ 
Sbjct: 150 SGADYPDELQCLDAPVLSQAKCEASY-PGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNG 208

Query: 232 PGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAAS 277
                   L GV SWGDGC +  KPGVYT+V  +  W++  ++A S
Sbjct: 209 Q-------LQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 247


>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
          Length = 423

 Score =  122 bits (305), Expect = 1e-27
 Identities = 66/161 (40%), Positives = 89/161 (55%), Gaps = 5/161 (3%)

Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
           + RI+ H K+   +   D++L +L +PV    +   VCLP    E   G    + G+GAL
Sbjct: 260 LRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGAL 319

Query: 171 FEDGPEAEAVREARVPLLSTDTCR--RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLT 228
             DG     +R+A+V L+   TC   +A    + P  MLCAG L G  D+CQGDSGGPL 
Sbjct: 320 KNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITP-RMLCAGSLEGKTDACQGDSGGPLV 378

Query: 229 CSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWL 269
            S+   R    L G+ SWGD C +P KPGVYTRV   +DW+
Sbjct: 379 SSD--ARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 417


>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
          Length = 423

 Score =  122 bits (305), Expect = 1e-27
 Identities = 66/161 (40%), Positives = 89/161 (55%), Gaps = 5/161 (3%)

Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
           + RI+ H K+   +   D++L +L +PV    +   VCLP    E   G    + G+GAL
Sbjct: 260 LRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGAL 319

Query: 171 FEDGPEAEAVREARVPLLSTDTCR--RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLT 228
             DG     +R+A+V L+   TC   +A    + P  MLCAG L G  D+CQGDSGGPL 
Sbjct: 320 KNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITP-RMLCAGSLEGKTDACQGDSGGPLV 378

Query: 229 CSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWL 269
            S+   R    L G+ SWGD C +P KPGVYTRV   +DW+
Sbjct: 379 SSD--ARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 417


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score =  121 bits (303), Expect = 2e-27
 Identities = 65/172 (37%), Positives = 95/172 (55%), Gaps = 4/172 (2%)

Query: 107 EEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGT-ACAIA 165
           +E  V +I+ H K++  T  ND+ALV++  P+S G    P CLP      P G+ +C +A
Sbjct: 121 QERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVA 180

Query: 166 GWGALFEDGPEAEAV-REARVPLLSTDTCRRALG-PGLRPSTMLCAGYLAGGVDSCQGDS 223
           GWG + E  P   ++  EARV L+  D C       G    T +CAGY  G +D+CQGDS
Sbjct: 181 GWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDS 240

Query: 224 GGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSA 275
           GGPL C +       V+ G+TSWG GC    +PG+YT    + +W+  ++ +
Sbjct: 241 GGPLMCKD-SKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGS 291


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  120 bits (302), Expect = 2e-27
 Identities = 99/275 (36%), Positives = 131/275 (47%), Gaps = 47/275 (17%)

Query: 31  LQGPCGERRPSTANVTRAHGRIVEKARHAGGGAGSPRGLRGVPLSFLRLS----CRSTRS 86
           LQ  CG  RP    V+ A GRIV       GG  +P G      S LRL     C  +  
Sbjct: 22  LQPGCG--RPQ---VSDAGGRIV-------GGHAAPAGAWPWQAS-LRLRRVHVCGGSLL 68

Query: 87  APNELLWTVTLAEGSRGEQAEEV--------------PVNRILPH--PKFDPRTFHNDLA 130
           +P  +L       GS      +V               V +I+ H  P   P T   D+A
Sbjct: 69  SPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQPGT-SGDIA 127

Query: 131 LVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGP--EAEAVREARVPLL 188
           LV+L  PV+      PVCLP+   +   G  C + GWG   E  P     ++RE +V ++
Sbjct: 128 LVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVV 187

Query: 189 STDTCRRAL-GPG---LRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVT 244
            T+TCRR   GPG   L+P  MLCA    G  D+CQ DSGGPL C   G     V  G+ 
Sbjct: 188 DTETCRRDYPGPGGSILQPD-MLCA---RGPGDACQDDSGGPLVCQVNGAW---VQAGIV 240

Query: 245 SWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSS 279
           SWG+GCG P +PGVYTRV  + +W++  ++A+  S
Sbjct: 241 SWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGS 275


>gi|118498341 chymotrypsin B1 [Homo sapiens]
          Length = 263

 Score =  120 bits (301), Expect = 3e-27
 Identities = 65/178 (36%), Positives = 95/178 (53%), Gaps = 7/178 (3%)

Query: 99  EGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPA 158
           +GS  E  + + + ++  +PKF   T +ND+ L++L TP     +   VCLP    + PA
Sbjct: 91  QGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPA 150

Query: 159 GTACAIAGWG-ALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVD 217
           GT CA  GWG   +      + +++A +PLLS   C+++ G  +    M+CAG  A GV 
Sbjct: 151 GTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKSWGRRI-TDVMICAG--ASGVS 207

Query: 218 SCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSA 275
           SC GDSGGPL C + G      L G+ SWG        PGVY RV     W+Q+ ++A
Sbjct: 208 SCMGDSGGPLVCQKDG---AWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQKILAA 262


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  120 bits (300), Expect = 4e-27
 Identities = 69/168 (41%), Positives = 91/168 (54%), Gaps = 11/168 (6%)

Query: 107 EEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAG 166
           +E+ V+R+   P         D+AL++L +P        P CLP         T C I G
Sbjct: 650 QEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITG 703

Query: 167 WGALFEDGPEAEAVREARVPLLSTDTCRR-ALGPGLRPSTMLCAGYLAGGVDSCQGDSGG 225
           WG   +    A  ++EA++P++    C R     G   ST LCAG+LAGG DSCQGDSGG
Sbjct: 704 WGET-QGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGG 762

Query: 226 PLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQM 273
           PL C E   + + +L GVTSWG GC  P KPGVY RV+ F  W++  M
Sbjct: 763 PLVCFE---KDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 807


>gi|4504383 HGF activator preproprotein [Homo sapiens]
          Length = 655

 Score =  119 bits (299), Expect = 5e-27
 Identities = 62/132 (46%), Positives = 82/132 (62%), Gaps = 7/132 (5%)

Query: 145 RPVCLPQEPQEPPAGTACAIAGWGALFED-GPEAEAVREARVPLLSTDTCR--RALGPGL 201
           +P+CLP+     PAG  C IAGWG L E+    + ++REA VPL++   C      G  +
Sbjct: 518 QPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADI 577

Query: 202 RPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTR 261
            P+ MLCAGY     D+CQGDSGGPL C + G      L+G+ SWGDGCG   KPGVYTR
Sbjct: 578 SPN-MLCAGYFDCKSDACQGDSGGPLACEKNGVA---YLYGIISWGDGCGRLHKPGVYTR 633

Query: 262 VAVFKDWLQEQM 273
           VA + DW+ +++
Sbjct: 634 VANYVDWINDRI 645


>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
          Length = 717

 Score =  119 bits (298), Expect = 7e-27
 Identities = 68/183 (37%), Positives = 98/183 (53%), Gaps = 8/183 (4%)

Query: 93  WTVTLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQL---WTPVSPGGSARPVCL 149
           WT  L    +G      PV RI+ H  ++ +TF  D+AL+QL   W P +     +P+C+
Sbjct: 533 WTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAW-PETLKQLIQPICI 591

Query: 150 PQEPQEPPAGTACAIAGWGALFE-DGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLC 208
           P   Q   +G  C + GWG   E D   +  +++A V L+    C    G  +  S MLC
Sbjct: 592 PPTGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYG--IITSRMLC 649

Query: 209 AGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDW 268
           AG ++G  D+C+GDSGGPL+C       + +L G+ SWG G G P  PGVYTRV+ F  W
Sbjct: 650 AGIMSGKRDACKGDSGGPLSCRRKSD-GKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPW 708

Query: 269 LQE 271
           + +
Sbjct: 709 IHK 711


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,957,613
Number of Sequences: 37866
Number of extensions: 1569529
Number of successful extensions: 5893
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 5304
Number of HSP's gapped (non-prelim): 355
length of query: 541
length of database: 18,247,518
effective HSP length: 107
effective length of query: 434
effective length of database: 14,195,856
effective search space: 6161001504
effective search space used: 6161001504
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.