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Search of human proteins with 169163549
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169163549 PREDICTED: hypothetical protein LOC646960 [Homo
sapiens]
(541 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169164924 PREDICTED: similar to hCG1818432 [Homo sapiens] 1117 0.0
gi|169163549 PREDICTED: hypothetical protein LOC646960 [Homo sap... 1117 0.0
gi|169164530 PREDICTED: similar to hCG1818432 [Homo sapiens] 1113 0.0
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 157 2e-38
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 147 2e-35
gi|110815798 ovochymase 1 [Homo sapiens] 145 7e-35
gi|145275213 coagulation factor XII precursor [Homo sapiens] 145 1e-34
gi|11415040 matriptase [Homo sapiens] 143 3e-34
gi|117956391 protease, serine, 33 [Homo sapiens] 142 1e-33
gi|223942069 enterokinase precursor [Homo sapiens] 139 5e-33
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 135 7e-32
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 135 7e-32
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 133 4e-31
gi|33695155 hepsin [Homo sapiens] 132 1e-30
gi|4504481 hepsin [Homo sapiens] 132 1e-30
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 130 3e-30
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 130 4e-30
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 127 3e-29
gi|4506153 prostasin preproprotein [Homo sapiens] 125 8e-29
gi|32698940 transmembrane protease, serine 12 [Homo sapiens] 123 5e-28
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 122 6e-28
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 122 8e-28
gi|40254871 transmembrane protease, serine 11E [Homo sapiens] 122 1e-27
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] 122 1e-27
gi|148613878 acrosin precursor [Homo sapiens] 121 2e-27
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 120 2e-27
gi|118498341 chymotrypsin B1 [Homo sapiens] 120 3e-27
gi|4505881 plasminogen [Homo sapiens] 120 4e-27
gi|4504383 HGF activator preproprotein [Homo sapiens] 119 5e-27
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 119 7e-27
>gi|169164924 PREDICTED: similar to hCG1818432 [Homo sapiens]
Length = 541
Score = 1117 bits (2888), Expect = 0.0
Identities = 541/541 (100%), Positives = 541/541 (100%)
Query: 1 MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60
MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG
Sbjct: 1 MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60
Query: 61 GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120
GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF
Sbjct: 61 GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120
Query: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180
DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV
Sbjct: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180
Query: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240
REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL
Sbjct: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240
Query: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300
FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA
Sbjct: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300
Query: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360
ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR
Sbjct: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360
Query: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420
RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK
Sbjct: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420
Query: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480
LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL
Sbjct: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480
Query: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQ 540
EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQ
Sbjct: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQ 540
Query: 541 P 541
P
Sbjct: 541 P 541
>gi|169163549 PREDICTED: hypothetical protein LOC646960 [Homo
sapiens]
Length = 541
Score = 1117 bits (2888), Expect = 0.0
Identities = 541/541 (100%), Positives = 541/541 (100%)
Query: 1 MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60
MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG
Sbjct: 1 MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60
Query: 61 GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120
GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF
Sbjct: 61 GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120
Query: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180
DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV
Sbjct: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180
Query: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240
REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL
Sbjct: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240
Query: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300
FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA
Sbjct: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300
Query: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360
ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR
Sbjct: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360
Query: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420
RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK
Sbjct: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420
Query: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480
LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL
Sbjct: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480
Query: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQ 540
EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQ
Sbjct: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQ 540
Query: 541 P 541
P
Sbjct: 541 P 541
>gi|169164530 PREDICTED: similar to hCG1818432 [Homo sapiens]
Length = 541
Score = 1113 bits (2880), Expect = 0.0
Identities = 540/541 (99%), Positives = 540/541 (99%)
Query: 1 MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60
MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG
Sbjct: 1 MLLAVLLLLPLPSSWFAHGHPLYTRLPPSALQGPCGERRPSTANVTRAHGRIVEKARHAG 60
Query: 61 GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120
GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF
Sbjct: 61 GGAGSPRGLRGVPLSFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKF 120
Query: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180
DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV
Sbjct: 121 DPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAV 180
Query: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240
REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL
Sbjct: 181 REARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVL 240
Query: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300
FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA
Sbjct: 241 FGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSREPSCRELLAWDPPQELQADA 300
Query: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360
ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR
Sbjct: 301 ARLCAFYARLCPGSQGACARLAHQQCLQRRRRCELRSLAHTLLGLLRNAQELLGPRPGLR 360
Query: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420
RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK
Sbjct: 361 RLAPALALPAPALRESPLHPARELRLHSGSRAAGTRFPKRRPEPRGEANGCPGLEPLRQK 420
Query: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480
LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL
Sbjct: 421 LAALQGAHAWILQVPSEHLAMNFHEVLADLGSKTLTGLFRAWVRAGLGGRHVAFSGLVGL 480
Query: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPPARQ 540
EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVP ARQ
Sbjct: 481 EPATLARSLPRLLVQALQAFRVAALAEGEPEGPWMDVGQGPGLERKGHHPLNPQVPAARQ 540
Query: 541 P 541
P
Sbjct: 541 P 541
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 157 bits (398), Expect = 2e-38
Identities = 83/171 (48%), Positives = 103/171 (60%), Gaps = 3/171 (1%)
Query: 103 GEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTAC 162
G + + V RI HP ++ T D+AL++L PV RP+CLP+ PP GT C
Sbjct: 890 GAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRC 949
Query: 163 AIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGD 222
I GWG++ E G A +++A V LLS TCRR P S MLCAG+ GGVDSC GD
Sbjct: 950 VITGWGSVREGGSMARQLQKAAVRLLSEQTCRR-FYPVQISSRMLCAGFPQGGVDSCSGD 1008
Query: 223 SGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQM 273
+GGPL C EP R VL GVTSWG GCG P PGVYTRVA + W+ + +
Sbjct: 1009 AGGPLACREPS--GRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHI 1057
Score = 134 bits (338), Expect = 2e-31
Identities = 78/184 (42%), Positives = 102/184 (55%), Gaps = 6/184 (3%)
Query: 103 GEQAEEV--PVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGT 160
G +A V V +I+ HP ++ T D+A+++L +P+ G +PVCLP P
Sbjct: 265 GSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSK 324
Query: 161 ACAIAGWGALFEDG-PEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSC 219
C I+GWG L ED + E +++A V LL C G L M+CAGYL G VDSC
Sbjct: 325 KCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLT-DRMVCAGYLDGKVDSC 383
Query: 220 QGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSS 279
QGDSGGPL C EP R L G+ SWG GC E +PGVY RV +DW+ E + AS
Sbjct: 384 QGDSGGPLVCEEPS--GRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASMP 441
Query: 280 REPS 283
P+
Sbjct: 442 LAPT 445
Score = 130 bits (328), Expect = 2e-30
Identities = 76/195 (38%), Positives = 108/195 (55%), Gaps = 7/195 (3%)
Query: 103 GEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTAC 162
G ++ + R++ HP ++P DLA+++L +P++ +PVCLP Q+ P G C
Sbjct: 567 GGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKC 626
Query: 163 AIAGWGALFE-DGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQG 221
I+GWG E + + E +++A V ++ TC L M+CAG+L G VDSCQG
Sbjct: 627 MISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSL-TDRMICAGFLEGKVDSCQG 685
Query: 222 DSGGPLTCSE-PGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAAS-SS 279
DSGGPL C E PG L G+ SWG GC + KPGVYTR+ K W+ E MS+
Sbjct: 686 DSGGPLACEEAPGV---FYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPM 742
Query: 280 REPSCRELLAWDPPQ 294
PS +LA P+
Sbjct: 743 SPPSTTRMLATTSPR 757
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 147 bits (371), Expect = 2e-35
Identities = 79/165 (47%), Positives = 99/165 (60%), Gaps = 5/165 (3%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
V +I+ H K+ P+ ND+AL++L P++ +PVCLP + P G C +GWGA
Sbjct: 287 VEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGAT 346
Query: 171 FEDGPEAEAV-REARVPLLSTDTCR-RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLT 228
+ +A V A VPL+S C R + G+ +MLCAGYL GGVDSCQGDSGGPL
Sbjct: 347 EDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLV 406
Query: 229 CSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQM 273
C E R L G TS+G GC E KPGVYTRV F DW+ EQM
Sbjct: 407 CQE---RRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQM 448
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 145 bits (367), Expect = 7e-35
Identities = 83/222 (37%), Positives = 120/222 (54%), Gaps = 12/222 (5%)
Query: 89 NELLWTVTLAEGSRG--EQAEEVP-VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSAR 145
N L WT+ + R E E+V I+ H F+ ++ +D+AL+QL +P+ R
Sbjct: 622 NPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVR 681
Query: 146 PVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRR---ALGPGLR 202
PVCLP + + CA+ GWG++ DG A +++ +V +L + C + PG
Sbjct: 682 PVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGI 741
Query: 203 PSTMLCAGYLAGG-VDSCQGDSGGPLTC-SEPGPRPREVLFGVTSWGDGCGEPGKPGVYT 260
M+CAG+ A G D CQGDSGGPL C E GP VL+G+ SWG GC +P KPGV+
Sbjct: 742 TEKMICAGFAASGEKDFCQGDSGGPLVCRHENGP---FVLYGIVSWGAGCVQPWKPGVFA 798
Query: 261 RVAVFKDWLQEQMSA-ASSSREPSCRELLAWDPPQELQADAA 301
RV +F DW+Q +++ AS C+ L PP D+A
Sbjct: 799 RVMIFLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSA 840
Score = 110 bits (276), Expect = 3e-24
Identities = 63/206 (30%), Positives = 105/206 (50%), Gaps = 19/206 (9%)
Query: 94 TVTLAEGS---RGEQAEEVPVNRILPHPKFDPRTFHN-DLALVQLWTPVSPGGSARPVCL 149
TVT E S + +Q + +PV++I+ HP+++ R + + D+AL+ L V G + +P+CL
Sbjct: 101 TVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICL 160
Query: 150 PQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPS---TM 206
P + G C +GWG + + + ++E +P++ C L P TM
Sbjct: 161 PDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTM 220
Query: 207 LCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKP---------- 256
LCAG+ G+D+CQGDSGGPL C G +L G+TSW GC P
Sbjct: 221 LCAGFPDWGMDACQGDSGGPLVCRRGG--GIWILAGITSWVAGCAGGSVPVRNNHVKASL 278
Query: 257 GVYTRVAVFKDWLQEQMSAASSSREP 282
G++++V+ D++ + + +P
Sbjct: 279 GIFSKVSELMDFITQNLFTGLDRGQP 304
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 145 bits (365), Expect = 1e-34
Identities = 104/282 (36%), Positives = 137/282 (48%), Gaps = 25/282 (8%)
Query: 12 PSSWFAHGHPLYTRLPPSALQ-GP--CGER-RPSTANVTRAHGRIVE-KARHAG-----G 61
P S P PPS + GP CG+R R S +++TR G +V + H
Sbjct: 333 PQSQTPGALPAKREQPPSLTRNGPLSCGQRLRKSLSSMTRVVGGLVALRGAHPYIAALYW 392
Query: 62 GAGSPRGLRGVPLSFLRLS-CRSTRSAPNELLWTVTLAEGSRG---EQAEEVPVNRILPH 117
G G P L + C R AP +L TV L + R E + + V H
Sbjct: 393 GHSFCAGSLIAPCWVLTAAHCLQDRPAPEDL--TVVLGQERRNHSCEPCQTLAVRSYRLH 450
Query: 118 PKFDPRTFHNDLALVQLWTPVSPGGS-----ARPVCLPQEPQEPPAGTACAIAGWGALFE 172
F P ++ +DLAL++L + +PVCLP P T C +AGWG FE
Sbjct: 451 EAFSPVSYQHDLALLRLQEDADGSCALLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFE 510
Query: 173 DGPE-AEAVREARVPLLSTDTCRR--ALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
E A ++EA+VP LS + C G + P MLCAG+L GG D+CQGDSGGPL C
Sbjct: 511 GAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPG-MLCAGFLEGGTDACQGDSGGPLVC 569
Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQE 271
+ R L G+ SWG GCG+ KPGVYT VA + W++E
Sbjct: 570 EDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAYYLAWIRE 611
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 143 bits (361), Expect = 3e-34
Identities = 78/197 (39%), Positives = 108/197 (54%), Gaps = 19/197 (9%)
Query: 75 SFLRLSCRSTRSAPNELLWTVTLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQL 134
+FL L +S RSAP +E + RI+ HP F+ TF D+AL++L
Sbjct: 674 AFLGLHDQSQRSAPG----------------VQERRLKRIISHPFFNDFTFDYDIALLEL 717
Query: 135 WTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCR 194
P RP+CLP PAG A + GWG G A +++ + +++ TC
Sbjct: 718 EKPAEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCE 777
Query: 195 RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPG 254
L + P M+C G+L+GGVDSCQGDSGGPL+ E R + GV SWGDGC +
Sbjct: 778 NLLPQQITP-RMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQA--GVVSWGDGCAQRN 834
Query: 255 KPGVYTRVAVFKDWLQE 271
KPGVYTR+ +F+DW++E
Sbjct: 835 KPGVYTRLPLFRDWIKE 851
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 142 bits (357), Expect = 1e-33
Identities = 99/266 (37%), Positives = 123/266 (46%), Gaps = 40/266 (15%)
Query: 35 CGERRPSTANVTRAHGR---------IVEKARHAGGGAGSPRGLRGVPLSFLRLSCRSTR 85
CG+ R S+ V GR I + H GG+ L C R
Sbjct: 28 CGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGS-----LIAPQWVLTAAHCFPRR 82
Query: 86 SAPNELLWTV-TLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSA 144
+ P E + L GS + VPV R+L P + DLAL+QL PV
Sbjct: 83 ALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARGDLALLQLRRPVPLSARV 142
Query: 145 RPVCLPQEPQEPPAGTACAIAGWGALFEDG---PEAEAVREARVPLLSTDTC-------- 193
+PVCLP PP GT C + GWG+L G PE ++ RVPLL + TC
Sbjct: 143 QPVCLPVPGARPPPGTPCRVTGWGSL-RPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGA 201
Query: 194 -----RRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGD 248
R + PG LCAGY G D+CQGDSGGPLTC + G VL GV SWG
Sbjct: 202 DVPQAERIVLPG-----SLCAGYPQGHKDACQGDSGGPLTCLQSG---SWVLVGVVSWGK 253
Query: 249 GCGEPGKPGVYTRVAVFKDWLQEQMS 274
GC P +PGVYT VA + W+Q ++S
Sbjct: 254 GCALPNRPGVYTSVATYSPWIQARVS 279
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 139 bits (351), Expect = 5e-33
Identities = 70/160 (43%), Positives = 98/160 (61%), Gaps = 3/160 (1%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
++ I+ +P ++ R ND+A++ L V+ +P+CLP+E Q P G C+IAGWG +
Sbjct: 859 IDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTV 918
Query: 171 FEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCS 230
G A ++EA VPLLS + C++ + M+CAGY GG+DSCQGDSGGPL C
Sbjct: 919 VYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQ 978
Query: 231 EPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQ 270
E R L GVTS+G C P +PGVY RV+ F +W+Q
Sbjct: 979 E---NNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWIQ 1015
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 135 bits (341), Expect = 7e-32
Identities = 71/166 (42%), Positives = 95/166 (57%), Gaps = 4/166 (2%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
V +++ HP +D +T +ND+AL++L P++ +PVCLP C I+GWGA
Sbjct: 365 VEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGAT 424
Query: 171 FEDGPEAEAVREARVPLLSTDTCR-RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
E G +E + A+V L+ T C R + L M+CAG+L G VDSCQGDSGGPL
Sbjct: 425 EEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVT 484
Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSA 275
S+ L G TSWG GC + +PGVY V VF DW+ QM A
Sbjct: 485 SK---NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRA 527
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 135 bits (341), Expect = 7e-32
Identities = 71/166 (42%), Positives = 95/166 (57%), Gaps = 4/166 (2%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
V +++ HP +D +T +ND+AL++L P++ +PVCLP C I+GWGA
Sbjct: 328 VEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGAT 387
Query: 171 FEDGPEAEAVREARVPLLSTDTCR-RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
E G +E + A+V L+ T C R + L M+CAG+L G VDSCQGDSGGPL
Sbjct: 388 EEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVT 447
Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSA 275
S+ L G TSWG GC + +PGVY V VF DW+ QM A
Sbjct: 448 SK---NNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRA 490
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 133 bits (335), Expect = 4e-31
Identities = 79/194 (40%), Positives = 100/194 (51%), Gaps = 6/194 (3%)
Query: 81 CRSTRSAPNELLWTVTLA---EGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTP 137
C S + +LWTV L + SR V+R+L HP + + D+AL+QL P
Sbjct: 618 CFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHP 677
Query: 138 VSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRAL 197
V + RPVCLP G C I GWGAL E GP + A+++ V L+ D C
Sbjct: 678 VVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVY 737
Query: 198 GPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPG 257
+ P MLCAGY G D+CQGDSGGPL C R L G+ SWG GCG P G
Sbjct: 738 RYQVTP-RMLCAGYRKGKKDACQGDSGGPLVCK--ALSGRWFLAGLVSWGLGCGRPNYFG 794
Query: 258 VYTRVAVFKDWLQE 271
VYTR+ W+Q+
Sbjct: 795 VYTRITGVISWIQQ 808
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 132 bits (331), Expect = 1e-30
Identities = 68/156 (43%), Positives = 92/156 (58%), Gaps = 4/156 (2%)
Query: 127 NDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVP 186
ND+ALV L +P+ +PVCLP Q G C + GWG G +A ++EARVP
Sbjct: 256 NDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVP 315
Query: 187 LLSTDTCRRA--LGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPR-PREVLFGV 243
++S D C A G ++P M CAGY GG+D+CQGDSGGP C + R PR L G+
Sbjct: 316 IISNDVCNGADFYGNQIKPK-MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGI 374
Query: 244 TSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSS 279
SWG GC KPGVYT+V+ F++W+ + + S +
Sbjct: 375 VSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEA 410
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 132 bits (331), Expect = 1e-30
Identities = 68/156 (43%), Positives = 92/156 (58%), Gaps = 4/156 (2%)
Query: 127 NDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGPEAEAVREARVP 186
ND+ALV L +P+ +PVCLP Q G C + GWG G +A ++EARVP
Sbjct: 256 NDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVP 315
Query: 187 LLSTDTCRRA--LGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPR-PREVLFGV 243
++S D C A G ++P M CAGY GG+D+CQGDSGGP C + R PR L G+
Sbjct: 316 IISNDVCNGADFYGNQIKPK-MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGI 374
Query: 244 TSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSS 279
SWG GC KPGVYT+V+ F++W+ + + S +
Sbjct: 375 VSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEA 410
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 130 bits (327), Expect = 3e-30
Identities = 69/163 (42%), Positives = 94/163 (57%), Gaps = 5/163 (3%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
V RI+PHP + + D+AL++L T ++ + VCLP + Q P G+ C ++GWG
Sbjct: 291 VERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHT 350
Query: 171 FEDGP-EAEAVREARVPLLSTDTCRRA-LGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLT 228
++ +++ VPL ST C + + G MLCAGYL G D+CQGDSGGPL
Sbjct: 351 HPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGGPLV 410
Query: 229 CSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQE 271
C + G R L GV SWG GC EP PGVY +VA F DW+ +
Sbjct: 411 CPD-GDTWR--LVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHD 450
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 130 bits (326), Expect = 4e-30
Identities = 66/160 (41%), Positives = 93/160 (58%), Gaps = 4/160 (2%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
V +I+ H + T ND+ALVQL T V + VCLP + P T+ + G+G++
Sbjct: 276 VRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSI 335
Query: 171 FEDGPEAEAVREARVPLLSTDTC-RRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
+DGP +R+ARV +STD C R+ + GL MLCAG++ G +D+C+GDSGGPL
Sbjct: 336 VDDGPIQNTLRQARVETISTDVCNRKDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLVY 395
Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWL 269
+ G+ SWG C P KPGVYTRV ++DW+
Sbjct: 396 DN---HDIWYIVGIVSWGQSCALPKKPGVYTRVTKYRDWI 432
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 127 bits (319), Expect = 3e-29
Identities = 69/163 (42%), Positives = 88/163 (53%), Gaps = 3/163 (1%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
V IL H + T ND+ALV+L V+ VCLP Q P G+ + GWGA
Sbjct: 255 VRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQ 314
Query: 171 FEDGPEAEAVREARVPLLSTDTCRRALG-PGLRPSTMLCAGYLAGGVDSCQGDSGGPLTC 229
G +R+ +V ++S D C G S MLCAG GGVD+CQGDSGGPL
Sbjct: 315 EYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLV- 373
Query: 230 SEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQ 272
+ R + G+ SWGD CG P KPGVYTRV + DW+++Q
Sbjct: 374 -QEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQ 415
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 125 bits (315), Expect = 8e-29
Identities = 67/195 (34%), Positives = 98/195 (50%), Gaps = 12/195 (6%)
Query: 101 SRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGT 160
S E A+ + I+PHP + D+AL+QL P++ RP+CLP P G
Sbjct: 107 SYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYIRPICLPAANASFPNGL 166
Query: 161 ACAIAGWGALFEDGP--EAEAVREARVPLLSTDTCRRALGPGLRP-------STMLCAGY 211
C + GWG + + +++ VPL+S +TC +P M+CAGY
Sbjct: 167 HCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDMVCAGY 226
Query: 212 LAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQE 271
+ GG D+CQGDSGGPL+C G L G+ SWGD CG +PGVYT + + W+Q
Sbjct: 227 VEGGKDACQGDSGGPLSCPVEG---LWYLTGIVSWGDACGARNRPGVYTLASSYASWIQS 283
Query: 272 QMSAASSSREPSCRE 286
+++ P +E
Sbjct: 284 KVTELQPRVVPQTQE 298
>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
Length = 348
Score = 123 bits (308), Expect = 5e-28
Identities = 71/201 (35%), Positives = 107/201 (53%), Gaps = 8/201 (3%)
Query: 84 TRSAPNELLWTVTLAEGS---RGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSP 140
T+ A + L+WT + + R +++ + I+ HP F ++ ND+AL L V
Sbjct: 124 TKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRY 183
Query: 141 GGSARPVCLPQEP-QEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCR--RAL 197
+P+CLP + Q T C I+GWG E+G +++A V +S + C R+
Sbjct: 184 NDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSY 243
Query: 198 GPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPG 257
G G+ P+T CAG G D+C+GDSGGPL C P + R + G+TS+G GCG G PG
Sbjct: 244 G-GIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYK-RFFVMGITSYGHGCGRRGFPG 301
Query: 258 VYTRVAVFKDWLQEQMSAASS 278
VY + ++ WL E AS+
Sbjct: 302 VYIGPSFYQKWLTEHFFHAST 322
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 122 bits (307), Expect = 6e-28
Identities = 57/171 (33%), Positives = 93/171 (54%), Gaps = 3/171 (1%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
+ I+ H + ++D+AL++L P++ +P+CLP + T C + GWG
Sbjct: 466 IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFS 525
Query: 171 FEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCS 230
E G +++ +PL++ + C++ M+CAGY GG D+C+GDSGGPL C
Sbjct: 526 KEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCK 585
Query: 231 EPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSSRE 281
G L G+TSWG+GC +PGVYT+VA + DW+ E+ ++ +
Sbjct: 586 HNG---MWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQ 633
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 122 bits (306), Expect = 8e-28
Identities = 64/166 (38%), Positives = 92/166 (55%), Gaps = 11/166 (6%)
Query: 113 RILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFE 172
+I+ HP++D +T +ND+ L++L + + LP P P GT C I+GWG
Sbjct: 92 KIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAP--PATGTKCLISGWGNTAS 149
Query: 173 DGPE-AEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLTCSE 231
G + + ++ P+LS C + PG S M C G+L GG DSCQGDSGGP+ C+
Sbjct: 150 SGADYPDELQCLDAPVLSQAKCEASY-PGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNG 208
Query: 232 PGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAAS 277
L GV SWGDGC + KPGVYT+V + W++ ++A S
Sbjct: 209 Q-------LQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS 247
>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
Length = 423
Score = 122 bits (305), Expect = 1e-27
Identities = 66/161 (40%), Positives = 89/161 (55%), Gaps = 5/161 (3%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
+ RI+ H K+ + D++L +L +PV + VCLP E G + G+GAL
Sbjct: 260 LRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGAL 319
Query: 171 FEDGPEAEAVREARVPLLSTDTCR--RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLT 228
DG +R+A+V L+ TC +A + P MLCAG L G D+CQGDSGGPL
Sbjct: 320 KNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITP-RMLCAGSLEGKTDACQGDSGGPLV 378
Query: 229 CSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWL 269
S+ R L G+ SWGD C +P KPGVYTRV +DW+
Sbjct: 379 SSD--ARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 417
>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
Length = 423
Score = 122 bits (305), Expect = 1e-27
Identities = 66/161 (40%), Positives = 89/161 (55%), Gaps = 5/161 (3%)
Query: 111 VNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGAL 170
+ RI+ H K+ + D++L +L +PV + VCLP E G + G+GAL
Sbjct: 260 LRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGAL 319
Query: 171 FEDGPEAEAVREARVPLLSTDTCR--RALGPGLRPSTMLCAGYLAGGVDSCQGDSGGPLT 228
DG +R+A+V L+ TC +A + P MLCAG L G D+CQGDSGGPL
Sbjct: 320 KNDGYSQNHLRQAQVTLIDATTCNEPQAYNDAITP-RMLCAGSLEGKTDACQGDSGGPLV 378
Query: 229 CSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWL 269
S+ R L G+ SWGD C +P KPGVYTRV +DW+
Sbjct: 379 SSD--ARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 417
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 121 bits (303), Expect = 2e-27
Identities = 65/172 (37%), Positives = 95/172 (55%), Gaps = 4/172 (2%)
Query: 107 EEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGT-ACAIA 165
+E V +I+ H K++ T ND+ALV++ P+S G P CLP P G+ +C +A
Sbjct: 121 QERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVA 180
Query: 166 GWGALFEDGPEAEAV-REARVPLLSTDTCRRALG-PGLRPSTMLCAGYLAGGVDSCQGDS 223
GWG + E P ++ EARV L+ D C G T +CAGY G +D+CQGDS
Sbjct: 181 GWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDS 240
Query: 224 GGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSA 275
GGPL C + V+ G+TSWG GC +PG+YT + +W+ ++ +
Sbjct: 241 GGPLMCKD-SKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGS 291
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 120 bits (302), Expect = 2e-27
Identities = 99/275 (36%), Positives = 131/275 (47%), Gaps = 47/275 (17%)
Query: 31 LQGPCGERRPSTANVTRAHGRIVEKARHAGGGAGSPRGLRGVPLSFLRLS----CRSTRS 86
LQ CG RP V+ A GRIV GG +P G S LRL C +
Sbjct: 22 LQPGCG--RPQ---VSDAGGRIV-------GGHAAPAGAWPWQAS-LRLRRVHVCGGSLL 68
Query: 87 APNELLWTVTLAEGSRGEQAEEV--------------PVNRILPH--PKFDPRTFHNDLA 130
+P +L GS +V V +I+ H P P T D+A
Sbjct: 69 SPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQPGT-SGDIA 127
Query: 131 LVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAGWGALFEDGP--EAEAVREARVPLL 188
LV+L PV+ PVCLP+ + G C + GWG E P ++RE +V ++
Sbjct: 128 LVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVV 187
Query: 189 STDTCRRAL-GPG---LRPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVT 244
T+TCRR GPG L+P MLCA G D+CQ DSGGPL C G V G+
Sbjct: 188 DTETCRRDYPGPGGSILQPD-MLCA---RGPGDACQDDSGGPLVCQVNGAW---VQAGIV 240
Query: 245 SWGDGCGEPGKPGVYTRVAVFKDWLQEQMSAASSS 279
SWG+GCG P +PGVYTRV + +W++ ++A+ S
Sbjct: 241 SWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGS 275
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 120 bits (301), Expect = 3e-27
Identities = 65/178 (36%), Positives = 95/178 (53%), Gaps = 7/178 (3%)
Query: 99 EGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPA 158
+GS E + + + ++ +PKF T +ND+ L++L TP + VCLP + PA
Sbjct: 91 QGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPA 150
Query: 159 GTACAIAGWG-ALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVD 217
GT CA GWG + + +++A +PLLS C+++ G + M+CAG A GV
Sbjct: 151 GTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKSWGRRI-TDVMICAG--ASGVS 207
Query: 218 SCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQMSA 275
SC GDSGGPL C + G L G+ SWG PGVY RV W+Q+ ++A
Sbjct: 208 SCMGDSGGPLVCQKDG---AWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQKILAA 262
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 120 bits (300), Expect = 4e-27
Identities = 69/168 (41%), Positives = 91/168 (54%), Gaps = 11/168 (6%)
Query: 107 EEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEPPAGTACAIAG 166
+E+ V+R+ P D+AL++L +P P CLP T C I G
Sbjct: 650 QEIEVSRLFLEPT------RKDIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITG 703
Query: 167 WGALFEDGPEAEAVREARVPLLSTDTCRR-ALGPGLRPSTMLCAGYLAGGVDSCQGDSGG 225
WG + A ++EA++P++ C R G ST LCAG+LAGG DSCQGDSGG
Sbjct: 704 WGET-QGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGG 762
Query: 226 PLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDWLQEQM 273
PL C E + + +L GVTSWG GC P KPGVY RV+ F W++ M
Sbjct: 763 PLVCFE---KDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVM 807
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 119 bits (299), Expect = 5e-27
Identities = 62/132 (46%), Positives = 82/132 (62%), Gaps = 7/132 (5%)
Query: 145 RPVCLPQEPQEPPAGTACAIAGWGALFED-GPEAEAVREARVPLLSTDTCR--RALGPGL 201
+P+CLP+ PAG C IAGWG L E+ + ++REA VPL++ C G +
Sbjct: 518 QPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADI 577
Query: 202 RPSTMLCAGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTR 261
P+ MLCAGY D+CQGDSGGPL C + G L+G+ SWGDGCG KPGVYTR
Sbjct: 578 SPN-MLCAGYFDCKSDACQGDSGGPLACEKNGVA---YLYGIISWGDGCGRLHKPGVYTR 633
Query: 262 VAVFKDWLQEQM 273
VA + DW+ +++
Sbjct: 634 VANYVDWINDRI 645
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 119 bits (298), Expect = 7e-27
Identities = 68/183 (37%), Positives = 98/183 (53%), Gaps = 8/183 (4%)
Query: 93 WTVTLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQL---WTPVSPGGSARPVCL 149
WT L +G PV RI+ H ++ +TF D+AL+QL W P + +P+C+
Sbjct: 533 WTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAW-PETLKQLIQPICI 591
Query: 150 PQEPQEPPAGTACAIAGWGALFE-DGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLC 208
P Q +G C + GWG E D + +++A V L+ C G + S MLC
Sbjct: 592 PPTGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYG--IITSRMLC 649
Query: 209 AGYLAGGVDSCQGDSGGPLTCSEPGPRPREVLFGVTSWGDGCGEPGKPGVYTRVAVFKDW 268
AG ++G D+C+GDSGGPL+C + +L G+ SWG G G P PGVYTRV+ F W
Sbjct: 650 AGIMSGKRDACKGDSGGPLSCRRKSD-GKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPW 708
Query: 269 LQE 271
+ +
Sbjct: 709 IHK 711
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,129,330
Number of Sequences: 37866
Number of extensions: 1577785
Number of successful extensions: 6004
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 5403
Number of HSP's gapped (non-prelim): 372
length of query: 541
length of database: 18,247,518
effective HSP length: 107
effective length of query: 434
effective length of database: 14,195,856
effective search space: 6161001504
effective search space used: 6161001504
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.