Guide to the Human Genome
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Search of human proteins with 169162266

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169162266 PREDICTED: hypothetical protein [Homo sapiens]
         (295 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169162266 PREDICTED: hypothetical protein [Homo sapiens]           592   e-169
gi|169161822 PREDICTED: hypothetical protein [Homo sapiens]           592   e-169
gi|169162655 PREDICTED: hypothetical protein [Homo sapiens]           592   e-169
gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]          46   4e-05
gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]          46   4e-05
gi|67782356 corneodesmosin precursor [Homo sapiens]                    46   4e-05
gi|153791670 keratin 76 [Homo sapiens]                                 43   4e-04
gi|161016767 mucin 21 [Homo sapiens]                                   42   5e-04
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          42   8e-04
gi|119395716 forkhead box C1 [Homo sapiens]                            41   0.001
gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatas...    41   0.001
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        40   0.002
gi|239508745 PREDICTED: hypothetical protein [Homo sapiens]            40   0.002
gi|4507917 WEE1 tyrosine kinase isoform 1 [Homo sapiens]               40   0.002
gi|116734702 homeobox D13 [Homo sapiens]                               40   0.003
gi|239752303 PREDICTED: hypothetical protein XP_002348193 [Homo ...    39   0.004
gi|239746814 PREDICTED: hypothetical protein XP_002343855 [Homo ...    39   0.004
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         39   0.004
gi|47132620 keratin 2 [Homo sapiens]                                   39   0.005
gi|7706435 headcase [Homo sapiens]                                     38   0.009
gi|109255251 loricrin [Homo sapiens]                                   37   0.016
gi|34452686 ring finger protein, LIM domain interacting [Homo sa...    37   0.021
gi|34452684 ring finger protein, LIM domain interacting [Homo sa...    37   0.021
gi|182765442 homeobox A10 isoform a [Homo sapiens]                     37   0.021
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ...    37   0.021
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi...    37   0.021
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 37   0.027
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          37   0.027
gi|110611914 progesterone receptor [Homo sapiens]                      37   0.027
gi|22538470 eomesodermin [Homo sapiens]                                37   0.027

>gi|169162266 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score =  592 bits (1527), Expect = e-169
 Identities = 295/295 (100%), Positives = 295/295 (100%)

Query: 1   MQLSWFMVFKCLATKAPKEMRVTILPQFVTPSLKTWIITRDNDFTSSSFLMSSFRSMPEK 60
           MQLSWFMVFKCLATKAPKEMRVTILPQFVTPSLKTWIITRDNDFTSSSFLMSSFRSMPEK
Sbjct: 1   MQLSWFMVFKCLATKAPKEMRVTILPQFVTPSLKTWIITRDNDFTSSSFLMSSFRSMPEK 60

Query: 61  EKHAGPHGLLCLNRRKIRLPTRGGKIATGIYRTQAVSWLRCTPSPTRRKVSSAFLLVAPD 120
           EKHAGPHGLLCLNRRKIRLPTRGGKIATGIYRTQAVSWLRCTPSPTRRKVSSAFLLVAPD
Sbjct: 61  EKHAGPHGLLCLNRRKIRLPTRGGKIATGIYRTQAVSWLRCTPSPTRRKVSSAFLLVAPD 120

Query: 121 LPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSG 180
           LPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSG
Sbjct: 121 LPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSG 180

Query: 181 RTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY 240
           RTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY
Sbjct: 181 RTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY 240

Query: 241 LSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG 295
           LSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG
Sbjct: 241 LSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG 295


>gi|169161822 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score =  592 bits (1527), Expect = e-169
 Identities = 295/295 (100%), Positives = 295/295 (100%)

Query: 1   MQLSWFMVFKCLATKAPKEMRVTILPQFVTPSLKTWIITRDNDFTSSSFLMSSFRSMPEK 60
           MQLSWFMVFKCLATKAPKEMRVTILPQFVTPSLKTWIITRDNDFTSSSFLMSSFRSMPEK
Sbjct: 1   MQLSWFMVFKCLATKAPKEMRVTILPQFVTPSLKTWIITRDNDFTSSSFLMSSFRSMPEK 60

Query: 61  EKHAGPHGLLCLNRRKIRLPTRGGKIATGIYRTQAVSWLRCTPSPTRRKVSSAFLLVAPD 120
           EKHAGPHGLLCLNRRKIRLPTRGGKIATGIYRTQAVSWLRCTPSPTRRKVSSAFLLVAPD
Sbjct: 61  EKHAGPHGLLCLNRRKIRLPTRGGKIATGIYRTQAVSWLRCTPSPTRRKVSSAFLLVAPD 120

Query: 121 LPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSG 180
           LPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSG
Sbjct: 121 LPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSG 180

Query: 181 RTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY 240
           RTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY
Sbjct: 181 RTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY 240

Query: 241 LSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG 295
           LSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG
Sbjct: 241 LSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG 295


>gi|169162655 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score =  592 bits (1527), Expect = e-169
 Identities = 295/295 (100%), Positives = 295/295 (100%)

Query: 1   MQLSWFMVFKCLATKAPKEMRVTILPQFVTPSLKTWIITRDNDFTSSSFLMSSFRSMPEK 60
           MQLSWFMVFKCLATKAPKEMRVTILPQFVTPSLKTWIITRDNDFTSSSFLMSSFRSMPEK
Sbjct: 1   MQLSWFMVFKCLATKAPKEMRVTILPQFVTPSLKTWIITRDNDFTSSSFLMSSFRSMPEK 60

Query: 61  EKHAGPHGLLCLNRRKIRLPTRGGKIATGIYRTQAVSWLRCTPSPTRRKVSSAFLLVAPD 120
           EKHAGPHGLLCLNRRKIRLPTRGGKIATGIYRTQAVSWLRCTPSPTRRKVSSAFLLVAPD
Sbjct: 61  EKHAGPHGLLCLNRRKIRLPTRGGKIATGIYRTQAVSWLRCTPSPTRRKVSSAFLLVAPD 120

Query: 121 LPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSG 180
           LPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSG
Sbjct: 121 LPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSG 180

Query: 181 RTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY 240
           RTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY
Sbjct: 181 RTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY 240

Query: 241 LSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG 295
           LSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG
Sbjct: 241 LSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG 295


>gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]
          Length = 508

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 37/108 (34%), Positives = 50/108 (46%), Gaps = 10/108 (9%)

Query: 173 SPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGASISS---SGAARRGG---RGACA 226
           SP+ SS   ++  F +G   +  SSSS     +  G+S+SS   SGA+R GG     A A
Sbjct: 31  SPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAA 90

Query: 227 GASANHRAGLPSPYL----SPGRGLLLRSQKSPSRAGGAAAAGPQAGP 270
            A+A   A L S       SPG      +  S + A  AAAA   + P
Sbjct: 91  AAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSP 138



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 39/126 (30%), Positives = 50/126 (39%), Gaps = 11/126 (8%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGS---YPSSSSSGDMMAS 205
           SSSSSSA   V GS  S   +   S    SS   A      + +      S S G    S
Sbjct: 54  SSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGS 113

Query: 206 AAGASISSSGAARRGGRGACAGAS--ANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAA 263
           +A +  SSS AA      A A +S  AN  +   +P +S G G            GG ++
Sbjct: 114 SAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSG------GGGGGGGGGSS 167

Query: 264 AGPQAG 269
           A  Q G
Sbjct: 168 AHSQDG 173



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 23/113 (20%)

Query: 141 ISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSG-SYPSSSSS 199
           +S   R   SSS++A      +  + LV         S   + G  P  S  S  SSS++
Sbjct: 74  VSGASRNGGSSSAAAAAAAAAAAAAALV---------SDSFSCGGSPGSSAFSLTSSSAA 124

Query: 200 GDMMASAAGASISS-------------SGAARRGGRGACAGASANHRAGLPSP 239
               A+AA AS S              SG +  GG G   G+SA+ + G   P
Sbjct: 125 AAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQP 177


>gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]
          Length = 490

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 37/108 (34%), Positives = 50/108 (46%), Gaps = 10/108 (9%)

Query: 173 SPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGASISS---SGAARRGG---RGACA 226
           SP+ SS   ++  F +G   +  SSSS     +  G+S+SS   SGA+R GG     A A
Sbjct: 13  SPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAA 72

Query: 227 GASANHRAGLPSPYL----SPGRGLLLRSQKSPSRAGGAAAAGPQAGP 270
            A+A   A L S       SPG      +  S + A  AAAA   + P
Sbjct: 73  AAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSP 120



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 39/126 (30%), Positives = 50/126 (39%), Gaps = 11/126 (8%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGS---YPSSSSSGDMMAS 205
           SSSSSSA   V GS  S   +   S    SS   A      + +      S S G    S
Sbjct: 36  SSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGS 95

Query: 206 AAGASISSSGAARRGGRGACAGAS--ANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAA 263
           +A +  SSS AA      A A +S  AN  +   +P +S G G            GG ++
Sbjct: 96  SAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSG------GGGGGGGGGSS 149

Query: 264 AGPQAG 269
           A  Q G
Sbjct: 150 AHSQDG 155



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 23/113 (20%)

Query: 141 ISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSG-SYPSSSSS 199
           +S   R   SSS++A      +  + LV         S   + G  P  S  S  SSS++
Sbjct: 56  VSGASRNGGSSSAAAAAAAAAAAAAALV---------SDSFSCGGSPGSSAFSLTSSSAA 106

Query: 200 GDMMASAAGASISS-------------SGAARRGGRGACAGASANHRAGLPSP 239
               A+AA AS S              SG +  GG G   G+SA+ + G   P
Sbjct: 107 AAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQP 159


>gi|67782356 corneodesmosin precursor [Homo sapiens]
          Length = 529

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 48/168 (28%), Positives = 75/168 (44%), Gaps = 31/168 (18%)

Query: 142 SSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSG----SYPSSS 197
           SS    + SS+ S+GGG  GS          S ++ + G +AG F  G+G    SY  SS
Sbjct: 71  SSSSGSSISSARSSGGGSSGSS---------SGSSIAQGGSAGSFKPGTGYSQVSY--SS 119

Query: 198 SSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSP-----GRGLLL--- 249
            SG  +  A+G+S   S ++  G  G+ +G+S++H +   S   S      G G  L   
Sbjct: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179

Query: 250 ----RSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPP 293
               R   +PS+ G ++++    G  +    S   VS   + C S  P
Sbjct: 180 DNSYRGILNPSQPGQSSSSSQTFGVSS----SGQSVSSNQRPCSSDIP 223



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 36/109 (33%), Positives = 45/109 (41%), Gaps = 25/109 (22%)

Query: 143 SDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSS---SS 199
           S  R  SSSS S+  G           LP  P  S+S       P G+GS+ SSS   SS
Sbjct: 394 SSSRVPSSSSISSSSG-----------LPYHPCGSASQSPCS--PPGTGSFSSSSSSQSS 440

Query: 200 GDMMASAAGASISSSGAARRGGRGACAGASANHRAGLP--SPYLSPGRG 246
           G ++    G+  SSSG         C   S+    G P  SP+  P  G
Sbjct: 441 GKIILQPCGSKSSSSG-------HPCMSVSSLTLTGGPDGSPHPDPSAG 482



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 27/92 (29%), Positives = 42/92 (45%), Gaps = 5/92 (5%)

Query: 174 PTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHR 233
           P    +  T+   P  +G   SS  S    +S++G+SISS+ ++  G  G+ +G+S    
Sbjct: 41  PCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQG 100

Query: 234 AGLPSPYLSPGRGLLLRSQKSPSRAGGAAAAG 265
               S    PG G    SQ S S   G++  G
Sbjct: 101 GSAGS--FKPGTGY---SQVSYSSGSGSSLQG 127


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 35/87 (40%), Positives = 39/87 (44%), Gaps = 10/87 (11%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAG 208
           SSSSSS+G GV G   S            SSG T GR    SGSY  SSSSG  +  A  
Sbjct: 541 SSSSSSSGYGVSGGSGS-------GYGGVSSGSTGGR--GSSGSY-QSSSSGSRLGGAGS 590

Query: 209 ASISSSGAARRGGRGACAGASANHRAG 235
            S+S SG     G    +G S     G
Sbjct: 591 ISVSHSGMGSSSGSIQTSGGSGYKSGG 617



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 21/111 (18%)

Query: 137 YREIISSD-CRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFP----RGSG 191
           YR+++  + CR +    S+           + V+   + T+ SSG + G F      GSG
Sbjct: 485 YRKLLEGEECRMSGECQSAV---------CISVVSNVTSTSGSSGSSRGVFGGVSGSGSG 535

Query: 192 SYP----SSSSSGDMMASAAGA---SISSSGAARRGGRGACAGASANHRAG 235
            Y     SSSSSG  ++  +G+    +SS     RG  G+   +S+  R G
Sbjct: 536 GYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLG 586



 Score = 32.7 bits (73), Expect = 0.39
 Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 8/110 (7%)

Query: 140 IISSDCRYNSSSSSSAG--GGVEGSDPSVLVLLPDSPTNSSSGR-TAGRFPRGSGSYPSS 196
           ++S+    + SS SS G  GGV GS          S ++SSSG   +G    G G   S 
Sbjct: 508 VVSNVTSTSGSSGSSRGVFGGVSGSGSGGYK--GGSSSSSSSGYGVSGGSGSGYGGVSSG 565

Query: 197 SSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRG 246
           S+ G     ++G+  SSS  +R GG G+ + + +   +   S   S G G
Sbjct: 566 STGG---RGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSG 612


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 34/129 (26%), Positives = 57/129 (44%), Gaps = 1/129 (0%)

Query: 141 ISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSG 200
           IS+     SS+ SS       S+ S      ++ TNS S  T+      + S  S++SSG
Sbjct: 282 ISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSG 341

Query: 201 DMMASAAGASISSSGAARRGGRGACAGASANHRA-GLPSPYLSPGRGLLLRSQKSPSRAG 259
              A+ + +S +SSGA+     G+   +S    A    S  +S G      S+ S + +G
Sbjct: 342 ASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSG 401

Query: 260 GAAAAGPQA 268
            + A   ++
Sbjct: 402 ASTATNSES 410



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 1/125 (0%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMA-SAA 207
           SS+ SS       SD S       + TNS S  T+      + S  S++SSG   A ++ 
Sbjct: 125 SSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSE 184

Query: 208 GASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAAGPQ 267
            +++SS  +       +   + A+      S   S G G    S+ S + +G + A   +
Sbjct: 185 SSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSE 244

Query: 268 AGPPT 272
           +  P+
Sbjct: 245 SSTPS 249



 Score = 36.2 bits (82), Expect = 0.035
 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 1/121 (0%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAG 208
           SS++SS  G    S+ S +     + TNS S   +      + S  S++SSG   A+ + 
Sbjct: 260 SSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSD 319

Query: 209 ASISSSGAA-RRGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAAGPQ 267
           +S +SSGA+       +   + A+      S   S G      S  S + +G + A   +
Sbjct: 320 SSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSE 379

Query: 268 A 268
           +
Sbjct: 380 S 380



 Score = 35.0 bits (79), Expect = 0.079
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 1/116 (0%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAG 208
           SS+ SS  G    S+ S       + TNS S   +      + S  S+ SSG   A+ + 
Sbjct: 245 SSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSE 304

Query: 209 ASISSSGA-ARRGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAA 263
           +S +SSGA        +   + A+      S   S G      S+ S + +G + A
Sbjct: 305 SSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTA 360



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 1/121 (0%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAG 208
           SS+ SS       S+ S       + TNS S  T+      + S  S++SSG   A+ + 
Sbjct: 185 SSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSE 244

Query: 209 ASISSSGA-ARRGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAAGPQ 267
           +S  SSGA        +   + A       S  +S G   +  S+ S   +G   A   +
Sbjct: 245 SSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSE 304

Query: 268 A 268
           +
Sbjct: 305 S 305



 Score = 32.0 bits (71), Expect = 0.67
 Identities = 24/88 (27%), Positives = 40/88 (45%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAG 208
           SS++SS       S+ S +     + T S S  T+      + S  S+ SSG   A+ + 
Sbjct: 365 SSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSE 424

Query: 209 ASISSSGAARRGGRGACAGASANHRAGL 236
           +S +SSGA      G+   ++ +  A L
Sbjct: 425 SSTTSSGANTATNSGSSVTSAGSGTAAL 452



 Score = 31.6 bits (70), Expect = 0.87
 Identities = 33/130 (25%), Positives = 50/130 (38%), Gaps = 2/130 (1%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAG 208
           SS++SS       S  S       + TNS S   +      + S  S++SSG   A+ + 
Sbjct: 350 SSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSE 409

Query: 209 ASISSSGAA-RRGGRGACAGASANHRAGLPSPYLSPGRG-LLLRSQKSPSRAGGAAAAGP 266
           +S  SSGA+       +   + AN      S   S G G   L    + S +   A +  
Sbjct: 410 SSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEA 469

Query: 267 QAGPPTVEVE 276
           + G   V  E
Sbjct: 470 KPGGSLVPWE 479



 Score = 30.0 bits (66), Expect = 2.5
 Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 17/118 (14%)

Query: 148 NSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAA 207
           +S++SS A                 + TNS S  T+      + S  S+ SSG   A+ +
Sbjct: 350 SSTTSSGA----------------STATNSGSSTTSSGTSTATNSESSTVSSGASTATTS 393

Query: 208 GASISSSGAA-RRGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAA 264
            +S +SSGA+       +   + A+      S   S G      S  S + AG   AA
Sbjct: 394 ESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAA 451


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 31/110 (28%), Positives = 41/110 (37%)

Query: 185 RFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSPG 244
           + P  SG   S +S     A +      S+ AA      A A A+A   A  P+P L+  
Sbjct: 466 QLPSSSGKISSGNSFPPQQAGSPLKRPFSAAAAIAAAAAAAAAAAAAAAAAAPAPALAAA 525

Query: 245 RGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPP 294
               L +  +P+ A  AA A   A  P V        S    H Q P  P
Sbjct: 526 AAPALAAAAAPALAAAAAPAPAPAAAPAVAAAPAAAASAAPSHSQKPSVP 575


>gi|119395716 forkhead box C1 [Homo sapiens]
          Length = 553

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 50/165 (30%), Positives = 64/165 (38%), Gaps = 30/165 (18%)

Query: 148 NSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSG----DMM 203
           +SSSS S+G    GS PS   L       S  G  +   P    + P   S G    ++M
Sbjct: 262 SSSSSLSSGSSPPGSLPSARPL-------SLDGADSAPPPPAPSAPPPHHSQGFSVDNIM 314

Query: 204 ASAAGASISSSGAARRGGRGACAGASANHRAGLPSPY----LSPGRGLLLRSQKSPSRA- 258
            S  G   S   AA     G  A A+A+ RAG+  P      SPG+  L  S  S + + 
Sbjct: 315 TSLRG---SPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTSSA 371

Query: 259 -------GGAAAAGPQAGPPT----VEVESDYRVSFEAKHCQSPP 292
                  GGA AAG   G  T    ++  S Y       H Q  P
Sbjct: 372 GSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAP 416



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 55/191 (28%), Positives = 72/191 (37%), Gaps = 35/191 (18%)

Query: 99  LRCTPSPTRRKVSSAFLL---------VAPDLPIGFVSLAPVACSRRYREIISSDCRYNS 149
           LR +P     ++SS  L          +AP L +G       A S     + SS C   S
Sbjct: 317 LRGSPQSAAAELSSGLLASAAASSRAGIAPPLALG-------AYSPGQSSLYSSPCSQTS 369

Query: 150 SSSSSAGG----------GVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSY----PS 195
           S+ SS GG          G  G+    L  +         G   G  P G+G      P 
Sbjct: 370 SAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGA-PGGAGGSAVDDPL 428

Query: 196 SSSSGDMMASAAGASISSSGAARRGGRGACAG-ASANHRAGLPSPYLSPGRGLLLRSQKS 254
              S   + S++ +S+S  G    GG G  AG   A H+  L S YL+   G L      
Sbjct: 429 PDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGGDL---GHL 485

Query: 255 PSRAGGAAAAG 265
            S A  AAAAG
Sbjct: 486 ASAAAAAAAAG 496


>gi|50726960 phosphatidylinositol (4,5) bisphosphate 5-phosphatase,
           A [Homo sapiens]
          Length = 638

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/133 (30%), Positives = 56/133 (42%), Gaps = 16/133 (12%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPD---SPTNSSSGRTAGRFPRGSGSYPSSS---SSGDM 202
           SSS+ S+G   EG D S L LL     SP+   S R   R P G   +P  +   SS + 
Sbjct: 480 SSSTDSSGTSSEGEDDSTLELLAPKSRSPSPGKSKRHRSRSP-GLARFPGLALRPSSRER 538

Query: 203 MASAAGASISSSGAAR----RGGRGACAGASANHRAGLPSPYLSP-----GRGLLLRSQK 253
             ++   S  S   +R    R   G+  G+S    +GLP P+  P       GLL   + 
Sbjct: 539 RGASRSPSPQSRRLSRVAPDRSSNGSSRGSSEEGPSGLPGPWAFPPAVPRSLGLLPALRL 598

Query: 254 SPSRAGGAAAAGP 266
                GG  + GP
Sbjct: 599 ETVDPGGGGSWGP 611


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 16/118 (13%)

Query: 142  SSDCRYNSSSSSSAGGGVEGSDPSVLVLLPD-------SPTNSSS-----GR----TAGR 185
            SS    +SSSSSS+G     S+ S L + P+       SPT +       GR    T  +
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAK 2602

Query: 186  FPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSP 243
              R S S  SSSSS    +S++ +S SSS ++      + + +S++     P P   P
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 37/126 (29%), Positives = 44/126 (34%), Gaps = 17/126 (13%)

Query: 142  SSDCRYNSSSSSSAGGGVEGSDPSVLVL-LPDSPTNSSSGRTAGRFPRGSGSYPSSSSS- 199
            SS    +SSSSSS+      + P    L  P SP     G    R PR        S S 
Sbjct: 2632 SSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSL 2691

Query: 200  ----------GDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRGLLL 249
                          +     S SS   +RRG RG     S   R   PSP     R +  
Sbjct: 2692 SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP-----RPMRH 2746

Query: 250  RSQKSP 255
            RS +SP
Sbjct: 2747 RSSRSP 2752



 Score = 28.9 bits (63), Expect = 5.6
 Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 7/136 (5%)

Query: 164  PSVLVLLPDSP---TNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGAS--ISSSGAAR 218
            PS L  L  +    ++SSS  ++      S S  SSSSSG   + + G+S  +    A +
Sbjct: 2518 PSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALK 2577

Query: 219  RGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESD 278
            R      A   A      P P  +P +     S  S S +  ++++   +   +    S 
Sbjct: 2578 RVPSPTPAPKEAVREGRPPEP--TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2635

Query: 279  YRVSFEAKHCQSPPPP 294
               S  +    S P P
Sbjct: 2636 SSSSSSSSSSSSSPSP 2651



 Score = 28.5 bits (62), Expect = 7.4
 Identities = 40/145 (27%), Positives = 57/145 (39%), Gaps = 26/145 (17%)

Query: 103  PSPTRRK---VSSAFLLVAPDLPIGFVSLAPVACSRRYREIISSDCRYNSSSSSSAGG-- 157
            PSP+ R     S + L  A D P    S  P A S + R +I+       S S S+G   
Sbjct: 2425 PSPSSRMGQAPSQSLLPPAQDQPR---SPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVA 2481

Query: 158  ---GVEGSDPSVLVL----LPDSPTNSSSGRTAGRFP-----------RGSGSYPSSSSS 199
                  G    +L +    +P S        T  + P           R S S  SSSSS
Sbjct: 2482 TTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541

Query: 200  GDMMASAAGASISSSGAARRGGRGA 224
                +S++ +S SSSG++     G+
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGS 2566


>gi|239508745 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 249

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 33/87 (37%), Positives = 41/87 (47%), Gaps = 6/87 (6%)

Query: 184 GRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSP 243
           GR P  +G  P+ S      A+A+GA+     A RR  R ACAG SA   AG  +P  + 
Sbjct: 122 GRLPWVTGPRPAGSLPAAQFAAASGAA----RAGRRRER-ACAGRSAGDAAGPEAPQPTG 176

Query: 244 GRGLLLRSQKSPSRAGGAAAAGPQAGP 270
           GRG   R   + S  GG A    Q  P
Sbjct: 177 GRG-CSRGSATASGVGGKAIKKAQRIP 202


>gi|4507917 WEE1 tyrosine kinase isoform 1 [Homo sapiens]
          Length = 646

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 41/141 (29%), Positives = 51/141 (36%), Gaps = 5/141 (3%)

Query: 129 APVACSRRYREIIS--SDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRF 186
           A  AC+ R + I S  SDC          G G    + S     PDSP   +   T    
Sbjct: 15  AGAACTLRQKLIFSPCSDCEEEEEEEEEEGSGHSTGEDSAFQE-PDSPLPPARSPTEPGP 73

Query: 187 PRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRG 246
            R     P+  S G++         +  GA   GG GA   +      G  SP  SP   
Sbjct: 74  ERRRSPGPAPGSPGELEEDLLLPG-ACPGADEAGG-GAEGDSWEEEGFGSSSPVKSPAAP 131

Query: 247 LLLRSQKSPSRAGGAAAAGPQ 267
             L S  SP R GG   A P+
Sbjct: 132 YFLGSSFSPVRCGGPGDASPR 152


>gi|116734702 homeobox D13 [Homo sapiens]
          Length = 343

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 20/110 (18%)

Query: 189 GSGSYPSSSSSGDMMASAA-----GASISSSGAARRGGRGACAGASANHRAGLPSPYLSP 243
           G+G  P+SSSS  + A+AA     G   +   A    GR A A A+A   A   S +  P
Sbjct: 18  GAGGAPASSSSSSVAAAAASGQCRGFLSAPVFAGTHSGRAAAAAAAAAAAAAAASGFAYP 77

Query: 244 GRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPP 293
           G      S  S S +    AA P+A P              AK C +P P
Sbjct: 78  GTSERTGSSSS-SSSSAVVAARPEAPP--------------AKECPAPTP 112


>gi|239752303 PREDICTED: hypothetical protein XP_002348193 [Homo
           sapiens]
          Length = 258

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 43/138 (31%), Positives = 54/138 (39%), Gaps = 22/138 (15%)

Query: 148 NSSSSSSAGGGVEGSDP------SVLVLLPDSPTNSSSGRTAGRFPRGSGS------YPS 195
           +S SSSS GGG   + P      S   ++P  P    SG        GSGS      +P 
Sbjct: 85  SSGSSSSRGGGAPVARPEPGRAASPGSMVPGPPAPPPSGDQQPAPSAGSGSTADLPEWPW 144

Query: 196 SSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSP 255
                 ++A   G +   +G     GR  CAG+ +   A  P    SPGR    R    P
Sbjct: 145 PLQLLLLLAPGRGCARGRAGE----GRAQCAGSPST--APRPRTCSSPGRATPHRPAGQP 198

Query: 256 SRAGGAA----AAGPQAG 269
           S  GGA       GP AG
Sbjct: 199 SHPGGAGCCPRVCGPAAG 216



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 11/84 (13%)

Query: 190 SGSYPSSSSSGDMMASAAGASISS-SGAARRGGRGACAGASANHRAGLPSPYLSPGRGLL 248
           S S+  +SSS  +++SAA     + + AA R  + + +G+S++   G P     PGR   
Sbjct: 49  SASFSVASSSMALLSSAAAPEEEAEAAAATRSPQPSSSGSSSSRGGGAPVARPEPGR--- 105

Query: 249 LRSQKSPSRAGGAAAAGPQAGPPT 272
                  + + G+   GP A PP+
Sbjct: 106 -------AASPGSMVPGPPAPPPS 122


>gi|239746814 PREDICTED: hypothetical protein XP_002343855 [Homo
           sapiens]
          Length = 258

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 43/138 (31%), Positives = 54/138 (39%), Gaps = 22/138 (15%)

Query: 148 NSSSSSSAGGGVEGSDP------SVLVLLPDSPTNSSSGRTAGRFPRGSGS------YPS 195
           +S SSSS GGG   + P      S   ++P  P    SG        GSGS      +P 
Sbjct: 85  SSGSSSSRGGGAPVARPEPGRAASPGSMVPGPPAPPPSGDQQPAPSAGSGSTADLPEWPW 144

Query: 196 SSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSP 255
                 ++A   G +   +G     GR  CAG+ +   A  P    SPGR    R    P
Sbjct: 145 PLQLLLLLAPGRGCARGRAGE----GRAQCAGSPST--APRPRTCSSPGRATPHRPAGQP 198

Query: 256 SRAGGAA----AAGPQAG 269
           S  GGA       GP AG
Sbjct: 199 SHPGGAGCCPRVCGPAAG 216



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 24/84 (28%), Positives = 41/84 (48%), Gaps = 11/84 (13%)

Query: 190 SGSYPSSSSSGDMMASAAGASISS-SGAARRGGRGACAGASANHRAGLPSPYLSPGRGLL 248
           S S+  +SSS  +++SAA     + + AA R  + + +G+S++   G P     PGR   
Sbjct: 49  SASFSVASSSMALLSSAAAPEEEAEAAAATRSPQPSSSGSSSSRGGGAPVARPEPGR--- 105

Query: 249 LRSQKSPSRAGGAAAAGPQAGPPT 272
                  + + G+   GP A PP+
Sbjct: 106 -------AASPGSMVPGPPAPPPS 122


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 45/180 (25%), Positives = 68/180 (37%), Gaps = 40/180 (22%)

Query: 142  SSDCRYNSSSSSSAGGGVEGSDP----------------SVLVLLPDSPTNSSSGRTAGR 185
            SS    +SSSSSS+G   EG +                 S       SP +SSS  ++  
Sbjct: 2564 SSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSS 2623

Query: 186  FPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRA----------- 234
                S S  SSSSS    +S++ +S SSS ++      + + +S++              
Sbjct: 2624 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDD 2683

Query: 235  -GLPSPYLSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPP 293
               P+P   P     L + K+  +AG A  +    G  T            A   Q+PPP
Sbjct: 2684 EAAPAPTAGPSAQAALPT-KATKQAGKARPSAHSPGKKT-----------PAPQPQAPPP 2731



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 44/140 (31%), Positives = 57/140 (40%), Gaps = 12/140 (8%)

Query: 132  ACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSG 191
            A S R     SS    +SSSSSS+      S  S       S ++SSS  ++      S 
Sbjct: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSSSSSSSSSS 2656

Query: 192  SYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRGLLLRS 251
            S  SSSSS    +S+     SS  +         AG SA  +A LP+   +   G    S
Sbjct: 2657 SSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSA--QAALPTK-ATKQAGKARPS 2713

Query: 252  QKSPSRAGGAAAAGPQAGPP 271
              SP +     A  PQA PP
Sbjct: 2714 AHSPGKK--TPAPQPQAPPP 2731



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 31/120 (25%), Positives = 46/120 (38%), Gaps = 5/120 (4%)

Query: 129  APVACSRRYREIISSDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPR 188
            +P + S       SS    +SSSSSS+      S  S       S ++SSS  ++     
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670

Query: 189  GSGSYPSSSSSGDMMASAAGASISSSG-----AARRGGRGACAGASANHRAGLPSPYLSP 243
             +    SS SS D  A A  A  S+       A ++ G+   +  S   +   P P   P
Sbjct: 2671 STTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPP 2730



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 22/99 (22%), Positives = 39/99 (39%), Gaps = 5/99 (5%)

Query: 171  PDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAG--- 227
            P SP  + + +        S S  S SSS    +S++G+         + G G C     
Sbjct: 2541 PKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGR 2600

Query: 228  --ASANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAA 264
              ++A+ RA  P+   S        S  S S +  ++++
Sbjct: 2601 NCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSS 2639


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 38.9 bits (89), Expect = 0.005
 Identities = 40/142 (28%), Positives = 55/142 (38%), Gaps = 15/142 (10%)

Query: 137 YREIISSD-CRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPS 195
           YR+++  + CR +   SS+    V  S  S  V      + ++ G + GR     G Y S
Sbjct: 480 YRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVA-----SKAAFGGSGGRGSSSGGGYSS 534

Query: 196 SSS--------SGDMMASAAGASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRGL 247
            SS        SG    S  G SIS  G    GG G   G+    + G  S     G G 
Sbjct: 535 GSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGG-GYGSGG 593

Query: 248 LLRSQKSPSRAGGAAAAGPQAG 269
              S    SR G ++  G  +G
Sbjct: 594 GKHSSGGGSRGGSSSGGGYGSG 615



 Score = 28.9 bits (63), Expect = 5.6
 Identities = 23/80 (28%), Positives = 28/80 (35%), Gaps = 1/80 (1%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAG 208
           S      GGG  G      V+   S  ++SS     R   G G +         +    G
Sbjct: 9   SRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGG 68

Query: 209 A-SISSSGAARRGGRGACAG 227
             SIS S A   GG GA  G
Sbjct: 69  TKSISISVAGGGGGFGAAGG 88


>gi|7706435 headcase [Homo sapiens]
          Length = 543

 Score = 38.1 bits (87), Expect = 0.009
 Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 13/95 (13%)

Query: 173 SPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGA--SISSSGAARRGGRGACAGASA 230
           +P NS  GR   R          ++SSGD   + AGA  +  ++GAA  G   A AG  A
Sbjct: 3   NPKNSKGGRKNKR----------ANSSGDEQENGAGALAAAGAAGAAAGGALAAAAGCGA 52

Query: 231 NHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAAG 265
              AG P    + G G       + + A GAAAAG
Sbjct: 53  A-AAGAPGAGGAAGAGGAGTGAANAAAAAGAAAAG 86


>gi|109255251 loricrin [Homo sapiens]
          Length = 312

 Score = 37.4 bits (85), Expect = 0.016
 Identities = 36/134 (26%), Positives = 45/134 (33%), Gaps = 20/134 (14%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSS---------SS 199
           S   SS GGG  G           S    SSG  +G F  G G +   +         SS
Sbjct: 111 SGCFSSGGGGSSGGGSGCF----SSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSS 166

Query: 200 GDMMASAAGASISSSGAAR----RGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSP 255
           G      +G   S  G        GG   C G S+    G  S Y+S  +         P
Sbjct: 167 GGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSG---GSGSGYVSSQQVTQTSCAPQP 223

Query: 256 SRAGGAAAAGPQAG 269
           S  GG++  G   G
Sbjct: 224 SYGGGSSGGGGSGG 237



 Score = 35.0 bits (79), Expect = 0.079
 Identities = 24/86 (27%), Positives = 30/86 (34%)

Query: 150 SSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGA 209
           SS    GGG+ G        +  S    SSG  +G F  G G     SS G   +     
Sbjct: 68  SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSG 127

Query: 210 SISSSGAARRGGRGACAGASANHRAG 235
             SS G    GG   C  +     +G
Sbjct: 128 CFSSGGGGSSGGGSGCFSSGGGGFSG 153



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 7/99 (7%)

Query: 143 SDCRYNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSS------SGRTAGRFPRGSGSYPSS 196
           S C Y+   S   GG   GS    +     + T+ +       G + G    GSG + SS
Sbjct: 185 SVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCF-SS 243

Query: 197 SSSGDMMASAAGASISSSGAARRGGRGACAGASANHRAG 235
              G       G+S   SG    GG   C G S+    G
Sbjct: 244 GGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGG 282


>gi|34452686 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 37.0 bits (84), Expect = 0.021
 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 6/75 (8%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMM-ASAA 207
           S    S GG   GS  S       S ++SSS  ++   P  S    SS +S D+   S  
Sbjct: 444 SGRGGSGGGSSSGSSSS-----SSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNE 498

Query: 208 GASISSSGAARRGGR 222
           G+S S S  ARR GR
Sbjct: 499 GSSSSGSSGARREGR 513



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 10/113 (8%)

Query: 107 RRKVSSAFLLVAPDLPIGFVSLAPVACSRRYREIISSDCRYN----SSSSSSAGGGVEGS 162
           R  VS+  + +   L  G      VA     R+I++     +    S S S   G V   
Sbjct: 376 RTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNR 435

Query: 163 DPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSG 215
           +      +  + + S  G + G    GS S  SSSSS    +S++ +  SSSG
Sbjct: 436 N------MERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSG 482



 Score = 28.9 bits (63), Expect = 5.6
 Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 8/59 (13%)

Query: 174 PTNSSSGRT-------AGRFPRGSGSYP-SSSSSGDMMASAAGASISSSGAARRGGRGA 224
           PT S S R        +GR   G GS   SSSSS    +S++ +S SSS ++  GG  +
Sbjct: 428 PTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESS 486


>gi|34452684 ring finger protein, LIM domain interacting [Homo
           sapiens]
          Length = 624

 Score = 37.0 bits (84), Expect = 0.021
 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 6/75 (8%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMM-ASAA 207
           S    S GG   GS  S       S ++SSS  ++   P  S    SS +S D+   S  
Sbjct: 444 SGRGGSGGGSSSGSSSS-----SSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNE 498

Query: 208 GASISSSGAARRGGR 222
           G+S S S  ARR GR
Sbjct: 499 GSSSSGSSGARREGR 513



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 10/113 (8%)

Query: 107 RRKVSSAFLLVAPDLPIGFVSLAPVACSRRYREIISSDCRYN----SSSSSSAGGGVEGS 162
           R  VS+  + +   L  G      VA     R+I++     +    S S S   G V   
Sbjct: 376 RTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDSDSEPTGSVSNR 435

Query: 163 DPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSG 215
           +      +  + + S  G + G    GS S  SSSSS    +S++ +  SSSG
Sbjct: 436 N------MERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSG 482



 Score = 28.9 bits (63), Expect = 5.6
 Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 8/59 (13%)

Query: 174 PTNSSSGRT-------AGRFPRGSGSYP-SSSSSGDMMASAAGASISSSGAARRGGRGA 224
           PT S S R        +GR   G GS   SSSSS    +S++ +S SSS ++  GG  +
Sbjct: 428 PTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESS 486


>gi|182765442 homeobox A10 isoform a [Homo sapiens]
          Length = 410

 Score = 37.0 bits (84), Expect = 0.021
 Identities = 36/126 (28%), Positives = 49/126 (38%), Gaps = 21/126 (16%)

Query: 190 SGSYPSSSSSGDMMASAAGA--SISSSGAARRGGRGACAGA----------------SAN 231
           S +YP++ S  +  A+ +    S+ SSG    GG G  AG                 +A+
Sbjct: 11  SPNYPTTMSCSESPAANSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAAD 70

Query: 232 HRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAAGPQA---GPPTVEVESDYRVSFEAKHC 288
              GL S  L P  G       SP   GG    GP A   GP  +++  D   S   +  
Sbjct: 71  LPYGLQSCGLFPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPP 130

Query: 289 QSPPPP 294
             PPPP
Sbjct: 131 DGPPPP 136


>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
            subunit [Homo sapiens]
          Length = 2339

 Score = 37.0 bits (84), Expect = 0.021
 Identities = 48/153 (31%), Positives = 61/153 (39%), Gaps = 34/153 (22%)

Query: 117  VAPDLPIGFVSLAPVACSR---RYREIISSDCRYNSSSSSSAG---------GGVEGSDP 164
            V P LP G     P  C R   R +E   S  R   SSSSS           GG E   P
Sbjct: 2085 VGPGLPPGE---GPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKP 2141

Query: 165  SVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRG- 223
                 L   PT+ ++G+  G  P+GSGS      +G  + S +GAS    G  R+  +  
Sbjct: 2142 KPS--LSSHPTSPTAGQEPGPHPQGSGSV-----NGSPLLSTSGASTPGRGGRRQLPQTP 2194

Query: 224  ---------ACAGASANHRAGLPS--PYLSPGR 245
                       A +S  H AG  +  P  SPGR
Sbjct: 2195 LTPRPSITYKTANSSPIHFAGAQTSLPAFSPGR 2227


>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
           sapiens]
          Length = 674

 Score = 37.0 bits (84), Expect = 0.021
 Identities = 33/117 (28%), Positives = 51/117 (43%), Gaps = 8/117 (6%)

Query: 149 SSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAG 208
           ++++++A G   G  P+     P  P   + GR A    R S S  SSS+S     S++ 
Sbjct: 342 AAAAAAASGVTTGKPPA-----PPQPGGPAPGRNASARRRSSSSSSSSSAS---RTSSSR 393

Query: 209 ASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAAG 265
           +S  SS  +RRGG    +G  A  R+   S   S  R       +    +GG +  G
Sbjct: 394 SSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDG 450


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 36.6 bits (83), Expect = 0.027
 Identities = 40/156 (25%), Positives = 56/156 (35%), Gaps = 22/156 (14%)

Query: 125 FVSLAPVACSRRY-REIISSDCRYNSSSSSSAGG---------GVEGSDPSVLVLLPDSP 174
           F  LAP     R+  E  ++  R +S  S S  G         G E  + S    +P + 
Sbjct: 433 FRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNN 492

Query: 175 TNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAARRGGRGACAGASANHRA 234
             S +GR       GSG    S+  G    S+ G   S  G   RGG+G+    S  ++ 
Sbjct: 493 WGSGNGR-------GSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQC 545

Query: 235 GLPSPYLSPGRGLLLRSQKSPSRAGGAAAAGPQAGP 270
                  + G G          R GG   +G   GP
Sbjct: 546 SRDGQGTAGGHG-----SGGGQRPGGGHGSGGGQGP 576


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 36.6 bits (83), Expect = 0.027
 Identities = 65/240 (27%), Positives = 88/240 (36%), Gaps = 63/240 (26%)

Query: 102 TPSPTRRKVSSAFLLVAPDLPI-GFVSLAPV---ACSRRYREIISSDCRYNSSSSSSAGG 157
           +P+P RR    +   V P  P+ G +S  P    A +   R ++SS           AGG
Sbjct: 105 SPAPGRRL---SLWAVPPGPPLSGGLSPDPKPGGAPTSSRRPLLSSPSWGGPEPEGRAGG 161

Query: 158 GVEGSD---PSV----LVLLPDSP------TNSSSGRTAGRF---------------PRG 189
           G+ GS    P      L + P  P      T ++SG  AG                 PR 
Sbjct: 162 GIPGSSSPHPGTGSRRLKVAPPPPAPKPCKTVTTSGAKAGGGKGAGSRLSWPESEGKPRV 221

Query: 190 SGSYPSSSSSGDMMASAAGASISSSG--AARRGGRGACAGA--SANHRAGL--------- 236
            GS  S+ +   + A+A  A+    G  A+  GG GA AGA    + R G          
Sbjct: 222 KGSKSSAGTGASVSAAATAAAAGGGGSTASTSGGVGAGAGARGKLSPRKGKSKTLDNSDL 281

Query: 237 -PSPYLSPGRGLLLRSQKSPSRAGGAAAAGPQAGPPTVEVESDYRVSFEAKHCQSPPPPG 295
            P P       L L    SP+ A  AA+A P    P + +E              PP PG
Sbjct: 282 HPGPPAGSPPPLTLPPTPSPATAVTAASAQPPGPAPPITLE--------------PPAPG 327


>gi|110611914 progesterone receptor [Homo sapiens]
          Length = 933

 Score = 36.6 bits (83), Expect = 0.027
 Identities = 42/143 (29%), Positives = 61/143 (42%), Gaps = 10/143 (6%)

Query: 103 PSPTRRKVSSAFLLVAPDLPIGFVSLAPVACSRRYREIIS-SDCRYNSSSSSSAGGGV-- 159
           PSP   +V+S++ L  P+LP      A  A  R    ++S S C+   SS ++A   V  
Sbjct: 129 PSPPACEVTSSWCLFGPELPED--PPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLP 186

Query: 160 EGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAA----GASISSSG 215
            G  P+  +LLP S +   SG      P+ +          +   SA     G   +  G
Sbjct: 187 RGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGG 246

Query: 216 AARRGGRGAC-AGASANHRAGLP 237
           AA  GG  A   GA+A   A +P
Sbjct: 247 AAAGGGAAAVPPGAAAGGVALVP 269



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 35/108 (32%), Positives = 46/108 (42%), Gaps = 8/108 (7%)

Query: 159 VEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASAAGASISSSGAAR 218
           V G++P+     PD P     G      PR + S P  ++     ASA+ +S SSSG+  
Sbjct: 406 VAGANPAAF---PDFPL----GPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTL 458

Query: 219 RGGRGACAGASANHRAGLPSPYLSPG-RGLLLRSQKSPSRAGGAAAAG 265
                   GA        P P  +PG  G LL     PS +  AAAAG
Sbjct: 459 ECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAG 506



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/141 (29%), Positives = 57/141 (40%), Gaps = 14/141 (9%)

Query: 147 YNSSSSSSAGGGVEGSDP--------SVL--VLLPDSPTNSSSGRTAGRFPRGSGSYPSS 196
           Y+ + ++   GG   S P        SVL  +L P  P  S     A      S      
Sbjct: 87  YSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVT-SSWCLFGP 145

Query: 197 SSSGDMMASAAGASISSSGAARRGGR-GACAGASANHRAGLPSPYLSPGRGLLLRSQKSP 255
               D  A+ A   + S   +R G + G  +G +A H+  LP   LSP R LLL + +SP
Sbjct: 146 ELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKV-LPRG-LSPARQLLLPASESP 203

Query: 256 SRAGGAAAAGPQAGPPTVEVE 276
             +G      PQA    VE E
Sbjct: 204 HWSGAPVKPSPQAAAVEVEEE 224


>gi|22538470 eomesodermin [Homo sapiens]
          Length = 686

 Score = 36.6 bits (83), Expect = 0.027
 Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 15/149 (10%)

Query: 147 YNSSSSSSAGGGVEGSDPSVLVLLPDSPTNSSSGRTAGRFPRGSGSYPSSSSSGDMMASA 206
           Y   S+    GG  G  PS       SP      + + +F   SGS    + SG+  A++
Sbjct: 20  YPLESARGGSGGSAGHLPSAA----PSPQKLDLDKASKKF---SGSLSCEAVSGEPAAAS 72

Query: 207 AGASISSSGAARRGGRGACAGASANHRAGLPSPYLSPGRGLLLRSQKSPSRAGGAAAAGP 266
           AGA  +       G   A A A+A  + G P       +G     ++ PS A  AAAA  
Sbjct: 73  AGAPAAMLSDTDAG--DAFASAAAVAKPGPP----DGRKGSPCGEEELPS-AAAAAAAAA 125

Query: 267 QAGPPTVEVESDYRVSFEAKHCQSPPPPG 295
            A   T     D  +S E  + QSP P G
Sbjct: 126 AAAAATARYSMD-SLSSERYYLQSPGPQG 153


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,661,934
Number of Sequences: 37866
Number of extensions: 720690
Number of successful extensions: 6009
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 395
Number of HSP's that attempted gapping in prelim test: 4438
Number of HSP's gapped (non-prelim): 1371
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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