Guide to the Human Genome
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Name: WEE1 Sequence: fasta or formatted (646aa) NCBI GI: 4507917
Description:

WEE1 tyrosine kinase isoform 1

Referenced in:

Cyclins and Related Functions
Spindle, M phase, and Meiosis
Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [432aa] WEE1 tyrosine kinase isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.7         50           3
 C cysteine            1.9         12           1
 D aspartate           5.1         33           2
 E glutamate           9.3         60          10
 F phenylalanine       3.6         23           1
 G glycine             7.4         48           3
 H histidine           2.6         17           1
 I isoleucine          3.9         25           1
 K lysine              5.4         35           2
 L leucine             8.4         54           3
 M methionine          2.2         14           1
 N asparagine          2.8         18           1
 P proline             7.3         47           4
 Q glutamine           3.3         21           2
 R arginine            8.0         52           3
 S serine             10.4         67           3
 T threonine           4.2         27           2
 V valine              3.9         25           2
 W tryptophan          0.8          5           1
 Y tyrosine            2.0         13           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   WEE1 tyrosine kinase isoform 1 
WEE1                  0.652   WEE1 tyrosine kinase isoform 2 
WEE2                  0.319   WEE1 homolog 2 
PKMYT1                0.096   protein kinase Myt1 isoform 2 
PKMYT1                0.096   protein kinase Myt1 isoform 1 
MST4                  0.059   serine/threonine protein kinase MST4 isoform 1 [Homo...
STK4                  0.055   serine/threonine kinase 4 
STK24                 0.054   serine/threonine kinase 24 isoform a 
STK24                 0.054   serine/threonine kinase 24 isoform b 
NEK4                  0.052   NIMA-related kinase 4 
STK3                  0.052   serine/threonine kinase 3 
STK25                 0.052   serine/threonine kinase 25 
NEK7                  0.048   NIMA-related kinase 7 
NEK1                  0.046   NIMA-related kinase 1 
NEK3                  0.044   NIMA-related kinase 3 isoform b 
PLK3                  0.044   polo-like kinase 3 
NEK3                  0.044   NIMA-related kinase 3 isoform a 
NEK3                  0.044   NIMA-related kinase 3 isoform a 
NEK5                  0.044   NIMA-related kinase 5 
NEK11                 0.042   NIMA-related kinase 11 isoform 2 
NEK11                 0.042   NIMA-related kinase 11 isoform 3 
NEK11                 0.042   NIMA-related kinase 11 isoform 1 
STK10                 0.042   serine/threonine kinase 10 
NEK6                  0.041   NIMA-related kinase 6 isoform 1 
NEK6                  0.041   NIMA-related kinase 6 isoform 2 
STK17A                0.041   serine/threonine kinase 17a 
DCLK1                 0.041   doublecortin-like kinase 1 
PLK2                  0.041   polo-like kinase 2 
ULK1                  0.040   Unc-51-like kinase 1 
PAK3                  0.040   p21-activated kinase 3 isoform d 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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