Guide to the Human Genome
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Search of human proteins with 168823443

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|168823443 RAD54-like 2 [Homo sapiens]
         (1467 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|168823443 RAD54-like 2 [Homo sapiens]                             2955   0.0  
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]   504   e-142
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]   504   e-142
gi|216548193 RAD54-like protein [Homo sapiens]                        246   9e-65
gi|216548186 RAD54-like protein [Homo sapiens]                        246   9e-65
gi|6912622 RAD54 homolog B [Homo sapiens]                             234   4e-61
gi|4557565 excision repair cross-complementing rodent repair def...   210   9e-54
gi|21914927 helicase, lymphoid-specific [Homo sapiens]                198   4e-50
gi|58331268 excision repair protein ERCC6-like [Homo sapiens]         181   6e-45
gi|58219008 RAD26L hypothetical protein [Homo sapiens]                180   8e-45
gi|190358534 SWI/SNF-related, matrix-associated actin-dependent ...   157   7e-38
gi|190358536 SWI/SNF-related, matrix-associated actin-dependent ...   154   6e-37
gi|190358532 SWI/SNF-related, matrix-associated actin-dependent ...   154   6e-37
gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto...   151   5e-36
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...   139   3e-32
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...   139   3e-32
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...   123   1e-27
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r...   123   1e-27
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r...   123   1e-27
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r...   123   1e-27
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r...   123   1e-27
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...   123   1e-27
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re...   123   1e-27
gi|164419749 SWI/SNF-related matrix-associated actin-dependent r...   118   4e-26
gi|21071058 SWI/SNF-related matrix-associated actin-dependent re...   114   7e-25
gi|21071044 SWI/SNF-related matrix-associated actin-dependent re...   109   2e-23
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]        107   1e-22
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...   105   2e-22
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa...   105   3e-22
gi|118421089 chromodomain helicase DNA binding protein 2 isoform...   104   7e-22

>gi|168823443 RAD54-like 2 [Homo sapiens]
          Length = 1467

 Score = 2955 bits (7661), Expect = 0.0
 Identities = 1467/1467 (100%), Positives = 1467/1467 (100%)

Query: 1    MSDESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRDDEEDLLDDPSLEGMCGTEHAQ 60
            MSDESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRDDEEDLLDDPSLEGMCGTEHAQ
Sbjct: 1    MSDESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRDDEEDLLDDPSLEGMCGTEHAQ 60

Query: 61   LGEDGQQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLRED 120
            LGEDGQQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLRED
Sbjct: 61   LGEDGQQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLRED 120

Query: 121  QLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQ 180
            QLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQ
Sbjct: 121  QLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQ 180

Query: 181  EVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSEDDEEEEKGGTHVNDVLN 240
            EVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSEDDEEEEKGGTHVNDVLN
Sbjct: 181  EVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSEDDEEEEKGGTHVNDVLN 240

Query: 241  QRDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFG 300
            QRDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFG
Sbjct: 241  QRDALGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFG 300

Query: 301  CILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPAD 360
            CILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPAD
Sbjct: 301  CILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPAD 360

Query: 361  NKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGR 420
            NKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGR
Sbjct: 361  NKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGR 420

Query: 421  PKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALK 480
            PKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALK
Sbjct: 421  PKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALK 480

Query: 481  NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQD 540
            NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQD
Sbjct: 481  NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQD 540

Query: 541  VRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRD 600
            VRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRD
Sbjct: 541  VRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRD 600

Query: 601  CGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQ 660
            CGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQ
Sbjct: 601  CGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQ 660

Query: 661  GTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENS 720
            GTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENS
Sbjct: 661  GTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENS 720

Query: 721  PKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNI 780
            PKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNI
Sbjct: 721  PKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNI 780

Query: 781  SYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNP 840
            SYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNP
Sbjct: 781  SYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNP 840

Query: 841  CHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTR 900
            CHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTR
Sbjct: 841  CHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTR 900

Query: 901  KEVENLLHFVEKEPAPQVSLNVKGIKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKL 960
            KEVENLLHFVEKEPAPQVSLNVKGIKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKL
Sbjct: 901  KEVENLLHFVEKEPAPQVSLNVKGIKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKL 960

Query: 961  TKAEKKAAKKSYEEDKRTSVPYTRPSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDEKPV 1020
            TKAEKKAAKKSYEEDKRTSVPYTRPSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDEKPV
Sbjct: 961  TKAEKKAAKKSYEEDKRTSVPYTRPSYAQYYPASDQSLTSIPAFSQRNWQPTLKGDEKPV 1020

Query: 1021 ASVRPVQSTPIPMMPRHVPLGGSVSSASSTNPSMNFPINYLQRAGVLVQKVVTTTDIVIP 1080
            ASVRPVQSTPIPMMPRHVPLGGSVSSASSTNPSMNFPINYLQRAGVLVQKVVTTTDIVIP
Sbjct: 1021 ASVRPVQSTPIPMMPRHVPLGGSVSSASSTNPSMNFPINYLQRAGVLVQKVVTTTDIVIP 1080

Query: 1081 GLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKVPEDGRMAASGSQG 1140
            GLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKVPEDGRMAASGSQG
Sbjct: 1081 GLNSSTDVQARINAGESIHIIRGTKGTYIRTSDGRIFAVRATGKPKVPEDGRMAASGSQG 1140

Query: 1141 PSCESTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSTNA 1200
            PSCESTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSTNA
Sbjct: 1141 PSCESTSNGRHSASSPKAPDPEGLARPVSPDSPEIISELQQYADVAAARESRQSSPSTNA 1200

Query: 1201 ALPGPPAQLMDSSAVPGTALGTEPRLGGHCLNSSLLVTGQPCGDRHPVLDLRGHKRKLAT 1260
            ALPGPPAQLMDSSAVPGTALGTEPRLGGHCLNSSLLVTGQPCGDRHPVLDLRGHKRKLAT
Sbjct: 1201 ALPGPPAQLMDSSAVPGTALGTEPRLGGHCLNSSLLVTGQPCGDRHPVLDLRGHKRKLAT 1260

Query: 1261 PPAAQESSRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTTPFTSQAGENSLFM 1320
            PPAAQESSRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTTPFTSQAGENSLFM
Sbjct: 1261 PPAAQESSRRRSRKGHLPAPVQPYEHGYPVSGGFAMPPVSLNHNLTTPFTSQAGENSLFM 1320

Query: 1321 GSTPSYYQLSNLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLNPSVPGILP 1380
            GSTPSYYQLSNLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLNPSVPGILP
Sbjct: 1321 GSTPSYYQLSNLLADARLVFPVTTDPLVPAGPVSSSSTATSVTASNPSFMLNPSVPGILP 1380

Query: 1381 SYSLPFSQPLLSEPRMFAPFPSPVLPSNLSRGMSIYPGYMSPHAGYPAGGLLRSQVPPFD 1440
            SYSLPFSQPLLSEPRMFAPFPSPVLPSNLSRGMSIYPGYMSPHAGYPAGGLLRSQVPPFD
Sbjct: 1381 SYSLPFSQPLLSEPRMFAPFPSPVLPSNLSRGMSIYPGYMSPHAGYPAGGLLRSQVPPFD 1440

Query: 1441 SHEVAEVGFSSNDDEDKDDDVIEVTGK 1467
            SHEVAEVGFSSNDDEDKDDDVIEVTGK
Sbjct: 1441 SHEVAEVGFSSNDDEDKDDDVIEVTGK 1467


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score =  504 bits (1297), Expect = e-142
 Identities = 377/1162 (32%), Positives = 575/1162 (49%), Gaps = 194/1162 (16%)

Query: 3    DESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRD---DEEDLLDDPSLEGM--CGTE 57
            DE+ S S P    D + ++  E    +++ +EE   +   DE+   DD   EG    G +
Sbjct: 1209 DEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQ 1268

Query: 58   HAQLGEDGQQPPRCTSTTSSQSEPSEQLR------RHQGKNLASEDPKKKRAQKPSHMR- 110
            + +   D +   +  S + S SE S++ R      RH+      E  ++K+ +   H   
Sbjct: 1269 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEV 1328

Query: 111  --RNIRKLLRED------QLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEE 162
              RN RK+  ED      Q   V++   + E E+R R    +K                E
Sbjct: 1329 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL-------------E 1375

Query: 163  IALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSGEE------------- 209
               R+    +   R+  QE    ++ S SE+E+  ++E  E    EE             
Sbjct: 1376 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1435

Query: 210  ------------DTLHIVDSSESVSEDDE------EEEKGGTHVNDVLNQRDA------- 244
                        D     ++  ++ E++E      E E+    + +V+   DA       
Sbjct: 1436 GKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPI 1495

Query: 245  LGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILA 304
              +++++ +   +E  V +   +   +KPHQ+ G++F++D   ES+++ K S G GCILA
Sbjct: 1496 TTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILA 1555

Query: 305  HSMGLGKTLQVISFID--VLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNK 362
            H MGLGKTLQV+SF+   +L       T L + P+NT  NW+ EF  W    E L  D K
Sbjct: 1556 HCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKW---QEGLKDDEK 1612

Query: 363  PEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPK 422
             E  +    K             R+ ++  W  +GGV+++GYEMYR L      A GR  
Sbjct: 1613 LEVSELATVK---------RPQERSYMLQRWQEDGGVMIIGYEMYRNL------AQGRNV 1657

Query: 423  KTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNI 482
            K++K                  +  F KAL  PGPD V+CDEGH +KN  ++ S+A+ +I
Sbjct: 1658 KSRK-----------------LKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSI 1700

Query: 483  RSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVR 542
            RSRRR++LTG PLQNNLIEY CMV+F++ + LG+ +EF N F  PI NGQC DST  DVR
Sbjct: 1701 RSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVR 1760

Query: 543  LMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCG 602
            +M+ R+H+L+ +L G VQR+ +T L   LP K E V+ VR++ IQ  LY  ++D     G
Sbjct: 1761 VMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVG 1820

Query: 603  SS-----GWLGLNPLKAFCVCCKIWNHPDVLY-------------EALQKESLANEQDLD 644
            ++     G  G    + F +  +IW HP  L              E    E +A++ D  
Sbjct: 1821 NNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDET 1880

Query: 645  VEELGSAGTSARCPPQGTKGKGEDSTLASSMG------EATNSKFLQGVGFNPFQERGNN 698
               L S   + +   +G KGK + S+  S         +  NS+  +G G     E GNN
Sbjct: 1881 SMSLSSDDYTKK-KKKGKKGKKDSSSSGSGSDNDVEVIKVWNSR-SRGGGEGNVDETGNN 1938

Query: 699  -------------------IVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDK 739
                                   +W KD +T+    VLE+S KMVLLF ++  + ++GDK
Sbjct: 1939 PSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDK 1998

Query: 740  ILVFSQSLSTLALIEEFLGKREVPCPPGTEG-------QGAQKWVRNISYFRLDGSTPAF 792
            +LVFSQSL +L LIE+FL   E+     TE        +G  KW+RNI Y+RLDGST A 
Sbjct: 1999 VLVFSQSLISLDLIEDFL---ELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQ 2055

Query: 793  ERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYR 852
             R++   +FND +N+   LF++ST+AG LG+NL+ ANRV++FDASWNP +D Q++ RVYR
Sbjct: 2056 SRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYR 2115

Query: 853  YGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHF--- 909
            +GQ KP Y+YR +A  T+E KIYDRQ++KQ +S RVVD      +FT  E+  L  F   
Sbjct: 2116 FGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPD 2175

Query: 910  ---------VEKEPAPQVSLNVKGIKESVL-QLACLKYPHLITKEPFEHESLLLNRKDHK 959
                      +K   P +       K+++L +L  +   H++     EH+SLL ++++ +
Sbjct: 2176 LLDDPNSEKKKKRDTPMLP------KDTILAELLQIHKEHIVGYH--EHDSLLDHKEEEE 2227

Query: 960  LTKAEKKAAKKSYEEDKR-TSVPYTRPSYAQYYPASDQSLT--------SIPAFSQRNWQ 1010
            LT+ E+KAA   YE +K+  ++ +  P+     P S  S T        ++ A S +  +
Sbjct: 2228 LTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLE 2287

Query: 1011 PTL-KGDEKPVASVRPVQSTPI 1031
              + +G EK V +   V +  I
Sbjct: 2288 DLINQGREKVVEATNSVTAVRI 2309



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 30/151 (19%)

Query: 1    MSDESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRDDEEDLLDDPSLEGMCGTEHAQ 60
            + ++S+S +  + + + E ++ EEEEEEEE        ++EED  DD    G    +  +
Sbjct: 1392 VQEDSSSENKSNSEEEEEEKEEEEEEEEEE-------EEEEEDENDDSKSPGKGRKKIRK 1444

Query: 61   LGEDGQQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLRED 120
            + +D                  ++LR      L  E+ ++KR  +    R  +R+++  +
Sbjct: 1445 ILKD------------------DKLRTETQNALKEEEERRKRIAEREREREKLREVIEIE 1486

Query: 121  QLEP-----VTKAAQQEELERRKRLEQQRKD 146
               P      TK    E+ E ++ L Q  ++
Sbjct: 1487 DASPTKCPITTKLVLDEDEETKEPLVQVHRN 1517


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score =  504 bits (1297), Expect = e-142
 Identities = 377/1162 (32%), Positives = 575/1162 (49%), Gaps = 194/1162 (16%)

Query: 3    DESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRD---DEEDLLDDPSLEGM--CGTE 57
            DE+ S S P    D + ++  E    +++ +EE   +   DE+   DD   EG    G +
Sbjct: 1247 DEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQ 1306

Query: 58   HAQLGEDGQQPPRCTSTTSSQSEPSEQLR------RHQGKNLASEDPKKKRAQKPSHMR- 110
            + +   D +   +  S + S SE S++ R      RH+      E  ++K+ +   H   
Sbjct: 1307 NEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEV 1366

Query: 111  --RNIRKLLRED------QLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEE 162
              RN RK+  ED      Q   V++   + E E+R R    +K                E
Sbjct: 1367 KGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL-------------E 1413

Query: 163  IALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSGEE------------- 209
               R+    +   R+  QE    ++ S SE+E+  ++E  E    EE             
Sbjct: 1414 ENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSP 1473

Query: 210  ------------DTLHIVDSSESVSEDDE------EEEKGGTHVNDVLNQRDA------- 244
                        D     ++  ++ E++E      E E+    + +V+   DA       
Sbjct: 1474 GKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPI 1533

Query: 245  LGRVLVNLNHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILA 304
              +++++ +   +E  V +   +   +KPHQ+ G++F++D   ES+++ K S G GCILA
Sbjct: 1534 TTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKSPGSGCILA 1593

Query: 305  HSMGLGKTLQVISFID--VLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNK 362
            H MGLGKTLQV+SF+   +L       T L + P+NT  NW+ EF  W    E L  D K
Sbjct: 1594 HCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKW---QEGLKDDEK 1650

Query: 363  PEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPK 422
             E  +    K             R+ ++  W  +GGV+++GYEMYR L      A GR  
Sbjct: 1651 LEVSELATVK---------RPQERSYMLQRWQEDGGVMIIGYEMYRNL------AQGRNV 1695

Query: 423  KTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNI 482
            K++K                  +  F KAL  PGPD V+CDEGH +KN  ++ S+A+ +I
Sbjct: 1696 KSRK-----------------LKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSI 1738

Query: 483  RSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVR 542
            RSRRR++LTG PLQNNLIEY CMV+F++ + LG+ +EF N F  PI NGQC DST  DVR
Sbjct: 1739 RSRRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVR 1798

Query: 543  LMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCG 602
            +M+ R+H+L+ +L G VQR+ +T L   LP K E V+ VR++ IQ  LY  ++D     G
Sbjct: 1799 VMKKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVG 1858

Query: 603  SS-----GWLGLNPLKAFCVCCKIWNHPDVLY-------------EALQKESLANEQDLD 644
            ++     G  G    + F +  +IW HP  L              E    E +A++ D  
Sbjct: 1859 NNSEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDET 1918

Query: 645  VEELGSAGTSARCPPQGTKGKGEDSTLASSMG------EATNSKFLQGVGFNPFQERGNN 698
               L S   + +   +G KGK + S+  S         +  NS+  +G G     E GNN
Sbjct: 1919 SMSLSSDDYTKK-KKKGKKGKKDSSSSGSGSDNDVEVIKVWNSR-SRGGGEGNVDETGNN 1976

Query: 699  -------------------IVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDK 739
                                   +W KD +T+    VLE+S KMVLLF ++  + ++GDK
Sbjct: 1977 PSVSLKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDK 2036

Query: 740  ILVFSQSLSTLALIEEFLGKREVPCPPGTEG-------QGAQKWVRNISYFRLDGSTPAF 792
            +LVFSQSL +L LIE+FL   E+     TE        +G  KW+RNI Y+RLDGST A 
Sbjct: 2037 VLVFSQSLISLDLIEDFL---ELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQ 2093

Query: 793  ERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYR 852
             R++   +FND +N+   LF++ST+AG LG+NL+ ANRV++FDASWNP +D Q++ RVYR
Sbjct: 2094 SRKKWAEEFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYR 2153

Query: 853  YGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLNPMLNFTRKEVENLLHF--- 909
            +GQ KP Y+YR +A  T+E KIYDRQ++KQ +S RVVD      +FT  E+  L  F   
Sbjct: 2154 FGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPD 2213

Query: 910  ---------VEKEPAPQVSLNVKGIKESVL-QLACLKYPHLITKEPFEHESLLLNRKDHK 959
                      +K   P +       K+++L +L  +   H++     EH+SLL ++++ +
Sbjct: 2214 LLDDPNSEKKKKRDTPMLP------KDTILAELLQIHKEHIVGYH--EHDSLLDHKEEEE 2265

Query: 960  LTKAEKKAAKKSYEEDKR-TSVPYTRPSYAQYYPASDQSLT--------SIPAFSQRNWQ 1010
            LT+ E+KAA   YE +K+  ++ +  P+     P S  S T        ++ A S +  +
Sbjct: 2266 LTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLE 2325

Query: 1011 PTL-KGDEKPVASVRPVQSTPI 1031
              + +G EK V +   V +  I
Sbjct: 2326 DLINQGREKVVEATNSVTAVRI 2347



 Score = 37.4 bits (85), Expect = 0.11
 Identities = 33/151 (21%), Positives = 65/151 (43%), Gaps = 30/151 (19%)

Query: 1    MSDESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRDDEEDLLDDPSLEGMCGTEHAQ 60
            + ++S+S +  + + + E ++ EEEEEEEE        ++EED  DD    G    +  +
Sbjct: 1430 VQEDSSSENKSNSEEEEEEKEEEEEEEEEE-------EEEEEDENDDSKSPGKGRKKIRK 1482

Query: 61   LGEDGQQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLRED 120
            + +D                  ++LR      L  E+ ++KR  +    R  +R+++  +
Sbjct: 1483 ILKD------------------DKLRTETQNALKEEEERRKRIAEREREREKLREVIEIE 1524

Query: 121  QLEP-----VTKAAQQEELERRKRLEQQRKD 146
               P      TK    E+ E ++ L Q  ++
Sbjct: 1525 DASPTKCPITTKLVLDEDEETKEPLVQVHRN 1555


>gi|216548193 RAD54-like protein [Homo sapiens]
          Length = 747

 Score =  246 bits (629), Expect = 9e-65
 Identities = 186/642 (28%), Positives = 293/642 (45%), Gaps = 145/642 (22%)

Query: 260 NVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFI 319
           +V + P L++ ++PHQ  G++FL+    E +   +     GCI+A  MGLGKTLQ I+ +
Sbjct: 142 HVVVDPILSKVLRPHQREGVKFLW----ECVTSRRIPGSHGCIMADEMGLGKTLQCITLM 197

Query: 320 DVLFRHTPA-----KTVLAIVPVNTLQNWLAEFNMWLP---PPEALPADNKPEEVQPRFF 371
             L R +P         + + P + ++NW  E   WL     P A+   +K E  Q    
Sbjct: 198 WTLLRQSPECKPEIDKAVVVSPSSLVKNWYNEVGKWLGGRIQPLAIDGGSKDEIDQ---- 253

Query: 372 KVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPV 431
           K+    ++     S             +L++ YE +RL                   H  
Sbjct: 254 KLEGFMNQRGARVSSP-----------ILIISYETFRL-------------------HVG 283

Query: 432 IIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLT 491
           ++                    +    +VICDEGHR+KN +  T QAL ++ + RRV+++
Sbjct: 284 VLQ-------------------KGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLIS 324

Query: 492 GYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVL 551
           G P+QN+L+EY+ +V FV    LGT  EF   FE PIL G+   ++  D +L   R   L
Sbjct: 325 GTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLREL 384

Query: 552 HSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGS--SGWLGL 609
            S++   + RR   +L  +LP K E V+  RL+ +Q +LY +F+ + +       G + +
Sbjct: 385 TSIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSV 444

Query: 610 NPLKAFCVCCKIWNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQGTKGKGEDS 669
           + L +     K+ NHP ++Y+   +           EE G  G     PP G   K  + 
Sbjct: 445 SSLSSITSLKKLCNHPALIYDKCVE-----------EEDGFVGALDLFPP-GYSSKALEP 492

Query: 670 TLASSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHL 729
            L+  M                                               +VL + L
Sbjct: 493 QLSGKM-----------------------------------------------LVLDYIL 505

Query: 730 IEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGST 789
                +  DK+++ S    TL L E+                      R   Y RLDG+ 
Sbjct: 506 AVTRSRSSDKVVLVSNYTQTLDLFEKLCR------------------ARRYLYVRLDGTM 547

Query: 790 PAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCR 849
              +R +++ +FN PS+   ++F+LS++AG  G+NLIGANR+V+FD  WNP +D QA+ R
Sbjct: 548 SIKKRAKVVERFNSPSS-PDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMAR 606

Query: 850 VYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDD 891
           V+R GQKK CYIYRL++  T+E+KI+ RQ  K+ +S  VVD+
Sbjct: 607 VWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDE 648


>gi|216548186 RAD54-like protein [Homo sapiens]
          Length = 747

 Score =  246 bits (629), Expect = 9e-65
 Identities = 186/642 (28%), Positives = 293/642 (45%), Gaps = 145/642 (22%)

Query: 260 NVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFI 319
           +V + P L++ ++PHQ  G++FL+    E +   +     GCI+A  MGLGKTLQ I+ +
Sbjct: 142 HVVVDPILSKVLRPHQREGVKFLW----ECVTSRRIPGSHGCIMADEMGLGKTLQCITLM 197

Query: 320 DVLFRHTPA-----KTVLAIVPVNTLQNWLAEFNMWLP---PPEALPADNKPEEVQPRFF 371
             L R +P         + + P + ++NW  E   WL     P A+   +K E  Q    
Sbjct: 198 WTLLRQSPECKPEIDKAVVVSPSSLVKNWYNEVGKWLGGRIQPLAIDGGSKDEIDQ---- 253

Query: 372 KVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPV 431
           K+    ++     S             +L++ YE +RL                   H  
Sbjct: 254 KLEGFMNQRGARVSSP-----------ILIISYETFRL-------------------HVG 283

Query: 432 IIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLT 491
           ++                    +    +VICDEGHR+KN +  T QAL ++ + RRV+++
Sbjct: 284 VLQ-------------------KGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLIS 324

Query: 492 GYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVL 551
           G P+QN+L+EY+ +V FV    LGT  EF   FE PIL G+   ++  D +L   R   L
Sbjct: 325 GTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLREL 384

Query: 552 HSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGS--SGWLGL 609
            S++   + RR   +L  +LP K E V+  RL+ +Q +LY +F+ + +       G + +
Sbjct: 385 TSIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSV 444

Query: 610 NPLKAFCVCCKIWNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQGTKGKGEDS 669
           + L +     K+ NHP ++Y+   +           EE G  G     PP G   K  + 
Sbjct: 445 SSLSSITSLKKLCNHPALIYDKCVE-----------EEDGFVGALDLFPP-GYSSKALEP 492

Query: 670 TLASSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHL 729
            L+  M                                               +VL + L
Sbjct: 493 QLSGKM-----------------------------------------------LVLDYIL 505

Query: 730 IEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGST 789
                +  DK+++ S    TL L E+                      R   Y RLDG+ 
Sbjct: 506 AVTRSRSSDKVVLVSNYTQTLDLFEKLCR------------------ARRYLYVRLDGTM 547

Query: 790 PAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCR 849
              +R +++ +FN PS+   ++F+LS++AG  G+NLIGANR+V+FD  WNP +D QA+ R
Sbjct: 548 SIKKRAKVVERFNSPSS-PDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMAR 606

Query: 850 VYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDD 891
           V+R GQKK CYIYRL++  T+E+KI+ RQ  K+ +S  VVD+
Sbjct: 607 VWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDE 648


>gi|6912622 RAD54 homolog B [Homo sapiens]
          Length = 910

 Score =  234 bits (598), Expect = 4e-61
 Identities = 183/659 (27%), Positives = 306/659 (46%), Gaps = 143/659 (21%)

Query: 260 NVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFI 319
           +V + P L   ++PHQ  GI FLY    E +   + +   G ILA  MGLGKTLQ IS I
Sbjct: 285 DVVIDPYLVYHLRPHQKEGIIFLY----ECVMGMRMNGRCGAILADEMGLGKTLQCISLI 340

Query: 320 DVLFRHTP------AKTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKV 373
             L    P       K  L + P + + NW  EF  WL                    K+
Sbjct: 341 WTLQCQGPYGGKPVIKKTLIVTPGSLVNNWKKEFQKWLGSER---------------IKI 385

Query: 374 HILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVII 433
             ++ +HK       +         VL++ YEM                        ++ 
Sbjct: 386 FTVDQDHKVEEFIKSIFYS------VLIISYEM------------------------LLR 415

Query: 434 DLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGY 493
            LD+  +  +F             D++ICDEGHR+KN    T+ AL ++   +R++LTG 
Sbjct: 416 SLDQI-KNIKF-------------DLLICDEGHRLKNSAIKTTTALISLSCEKRIILTGT 461

Query: 494 PLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHS 553
           P+QN+L E++ ++DFV P  LG+   +  ++E PI+  +   ++ ++  L   R+  L  
Sbjct: 462 PIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREPSASEEEKELGERRAAELTC 521

Query: 554 LLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDR--FRDCGSSGWLGLNP 611
           L   F+ RR   ++  +LP K ENV+  R   +Q +LY + ++    R C   G L  +P
Sbjct: 522 LTGLFILRRTQEIINKYLPPKIENVVFCRPGALQIELYRKLLNSQVVRFC-LQGLLENSP 580

Query: 612 LKAFCVCC--KIWNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQGTKGKGEDS 669
               C+    K+ NHP +L+ +++++  ++  D + E+    G  +  P           
Sbjct: 581 -HLICIGALKKLCNHPCLLFNSIKEKECSSTCDKNEEKSLYKGLLSVFPAD--------- 630

Query: 670 TLASSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHL 729
                              +NP                L T  ++G L+   K++ + H 
Sbjct: 631 -------------------YNPL---------------LFTEKESGKLQVLSKLLAVIHE 656

Query: 730 IEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGST 789
           +  +    +K+++ S    TL +++E   +                     +Y RLDG T
Sbjct: 657 LRPT----EKVVLVSNYTQTLNILQEVCKRH------------------GYAYTRLDGQT 694

Query: 790 PAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCR 849
           P  +R+++++ FN   + + ++FLLS++AG +G+NLIG + ++++D  WNP  D QA+ R
Sbjct: 695 PISQRQQIVDGFNSQHS-SFFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSR 753

Query: 850 VYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVD--DLNPMLNFTRKEVENL 906
           V+R GQK P +IYRL+   T+E+KIY RQISKQG+   VVD    +  + F+ +E++NL
Sbjct: 754 VWRDGQKYPVHIYRLLTTGTIEEKIYQRQISKQGLCGAVVDLTKTSEHIQFSVEELKNL 812


>gi|4557565 excision repair cross-complementing rodent repair
           deficiency, complementation group 6 [Homo sapiens]
          Length = 1493

 Score =  210 bits (534), Expect = 9e-54
 Identities = 172/610 (28%), Positives = 263/610 (43%), Gaps = 165/610 (27%)

Query: 300 GCILAHSMGLGKTLQVISFIDVL-----------FRHTPAKTVLAIVPVNTLQNWLAEFN 348
           G IL   MGLGKT+Q+I+F+  L           +R       + + P   +  W+ EF+
Sbjct: 527 GGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEGLGPTVIVCPTTVMHQWVKEFH 586

Query: 349 MWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYR 408
            W PP                 F+V IL++       + K++ D     G+L+  Y   R
Sbjct: 587 TWWPP-----------------FRVAILHETGSYTHKKEKLIRDVAHCHGILITSYSYIR 629

Query: 409 LLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRI 468
           L+                                      +  + R     VI DEGH+I
Sbjct: 630 LM--------------------------------------QDDISRYDWHYVILDEGHKI 651

Query: 469 KNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPI 528
           +N  A+ + A K  R+  R++L+G P+QNNL E W + DF+ P  LGT   F   F  PI
Sbjct: 652 RNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPI 711

Query: 529 LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLK--IHLPAKEENVILVRLSKI 586
             G   +++P  V+     + VL   +  ++ RR  + +K  + LP K E V+  RL+  
Sbjct: 712 TMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDE 771

Query: 587 QRDLYTQFMD-----RFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESLANEQ 641
           Q  +Y  F+D     R  +     + GL  L+  C      NHPD               
Sbjct: 772 QHKVYQNFVDSKEVYRILNGEMQIFSGLIALRKIC------NHPD--------------- 810

Query: 642 DLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGNNIVT 701
                 L S G      P+  KG  +D       G               + +R   ++ 
Sbjct: 811 ------LFSGG------PKNLKGLPDDELEEDQFG---------------YWKRSGKMIV 843

Query: 702 YEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKRE 761
            E                   ++ ++H      K G ++L+FSQS   L ++E FL    
Sbjct: 844 VE------------------SLLKIWH------KQGQRVLLFSQSRQMLDILEVFL---- 875

Query: 762 VPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCL 821
                      AQK+    +Y ++DG+T    R+ LI ++N+ +++  ++FLL+TR G L
Sbjct: 876 ----------RAQKY----TYLKMDGTTTIASRQPLITRYNEDTSI--FVFLLTTRVGGL 919

Query: 822 GVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISK 881
           GVNL GANRVV++D  WNP  D QA  R +R GQKK   +YRL+   T+E+KIY RQI K
Sbjct: 920 GVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFK 979

Query: 882 QGMSDRVVDD 891
           Q +++RV+ D
Sbjct: 980 QFLTNRVLKD 989


>gi|21914927 helicase, lymphoid-specific [Homo sapiens]
          Length = 838

 Score =  198 bits (503), Expect = 4e-50
 Identities = 217/858 (25%), Positives = 360/858 (41%), Gaps = 169/858 (19%)

Query: 111 RNIRKLLREDQLEP---VTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLPEEIALRA 167
           R ++ LL +  +     +TK  QQ+  E++K+ + +RK           E L  +    +
Sbjct: 66  RRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLERKK----------ESLKVKKGKNS 115

Query: 168 SDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSEDDEE 227
            D  +  P         +    G EDE  +  EV+     +E+ L +   ++  +ED E 
Sbjct: 116 IDASEEKP--------VMRKKRGREDESYNISEVMS----KEEILSVAKKNKKENED-EN 162

Query: 228 EEKGGTHVNDVLNQRDALGRVLVNLNHPPEEENVFLAPQLARA--------VKPHQIGGI 279
                  V D+   +D+   +   L+    +   F    + +            H  GG+
Sbjct: 163 SSSTNLCVEDLQKNKDSNSIIKDRLSETVRQNTKFFFDPVRKCNGQPVPFQQPKHFTGGV 222

Query: 280 RFLYDNLVESLE--RFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPV 337
              Y   VE +E  R    +G   ILA  MGLGKT+Q I+ I ++ +       L   P+
Sbjct: 223 MRWYQ--VEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPL 280

Query: 338 NTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEG 397
           +TL NW+AEF  + P            ++    +        H T   R K++ +     
Sbjct: 281 STLPNWMAEFKRFTP------------DIPTMLY--------HGTQEERQKLVRNIYKRK 320

Query: 398 GVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGP 457
           G L +                          HPV+I         E       AL     
Sbjct: 321 GTLQI--------------------------HPVVIT------SFEIAMRDRNALQHCYW 348

Query: 458 DVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTR 517
             +I DEGHRIKN +    + LK   +  +++LTG PLQNNL E W +++F+ PD     
Sbjct: 349 KYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDL 408

Query: 518 QEFSNMFERPILNGQCIDSTPQDVRLMRYRS---HVLHSLLEGFVQRRGHTVLKIHLPAK 574
           + F + F+   L+      T +D+          H+LH +L  F+ RR  + + + +P K
Sbjct: 409 KSFESWFDITSLS-----ETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPK 463

Query: 575 EENVILVRLSKIQRDLYTQFMDRF--RDCGSSG--WLGLNPL-------KAFCVCCKIWN 623
            E V+   LSK Q   YT  ++R      GSS    + L+P        +      KI +
Sbjct: 464 REVVVYAPLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGRPKRRTRKSINYSKIDD 523

Query: 624 HPDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKF 683
            P+ L + + +     +++  V E+          P  ++   +   +   + +  N  +
Sbjct: 524 FPNELEKLISQIQPEVDRERAVVEVNI--------PVESEVNLKLQNIMMLLRKCCNHPY 575

Query: 684 LQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVF 743
           L     +P        VT E+  D        ++ NS K ++L  ++ E  K G K+L+F
Sbjct: 576 LIEYPIDP--------VTQEFKID------EELVTNSGKFLILDRMLPELKKRGHKVLLF 621

Query: 744 SQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFN- 802
           SQ  S L ++ ++                    +R+ ++ RLDGS    ERE+ ++ FN 
Sbjct: 622 SQMTSMLDILMDYCH------------------LRDFNFSRLDGSMSYSEREKNMHSFNT 663

Query: 803 DPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIY 862
           DP     ++FL+STRAG LG+NL  A+ V+++D+ WNP  D QA  R +R GQ KP  +Y
Sbjct: 664 DPE---VFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVY 720

Query: 863 RLVADYTLEKKIYDRQISKQGMSDRVV---------DDLNPMLNF-TRKEVENLLHFVEK 912
           RLV   T+++KI +R  +K+ +   ++           LN   NF   KE+  LL   + 
Sbjct: 721 RLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLNLSKNFLDPKELMELLKSRDY 780

Query: 913 EPAPQVSLNVKGIKESVL 930
           E        +KG +E V+
Sbjct: 781 E------REIKGSREKVI 792


>gi|58331268 excision repair protein ERCC6-like [Homo sapiens]
          Length = 1250

 Score =  181 bits (458), Expect = 6e-45
 Identities = 181/676 (26%), Positives = 281/676 (41%), Gaps = 164/676 (24%)

Query: 261 VFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFID 320
           + L  +L   +  HQ  GI FLY     SL R     G   ILA  MGLGKT+Q+I+F+ 
Sbjct: 86  LLLYRELHNQLFEHQKEGIAFLY-----SLYRDGRKGG---ILADDMGLGKTVQIIAFLS 137

Query: 321 VLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEH 380
            +F  +    VL I+P N +  W+ EF  W  P   +   + P +            DE 
Sbjct: 138 GMFDASLVNHVLLIMPTNLINTWVKEFIKWT-PGMRVKTFHGPSK------------DER 184

Query: 381 KTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDR 440
               +R +         GV++  Y+M                            ++   +
Sbjct: 185 TRNLNRIQ------QRNGVIITTYQML---------------------------INNWQQ 211

Query: 441 QQEFR-REFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNL 499
              FR +EF         D VI DE H+IK     ++   + I +  R++LTG P+QNNL
Sbjct: 212 LSSFRGQEFVW-------DYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNNL 264

Query: 500 IEYWCMVDFV-RPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGF 558
            E W + DF  +   LGT + F   +E PI   +  D+TP +  L    S  L ++++ +
Sbjct: 265 QELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKPY 324

Query: 559 VQRRGHTVLKIH------------------------LPAKEENVILVRLSKIQRDLYTQF 594
             RR    ++                          L  K + +I +RL  +Q ++Y +F
Sbjct: 325 FLRRTKEDVQKKKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRKF 384

Query: 595 --MDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESLANEQDLDVEELGSAG 652
             +D  ++         +PL    V  K+ +HP +L  + +   L N      ++     
Sbjct: 385 VSLDHIKELLMET---RSPLAELGVLKKLCDHPRLL--SARACCLLNLGTFSAQD----- 434

Query: 653 TSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKDLLTNY 712
                       +GEDS     + + T+                                
Sbjct: 435 ----------GNEGEDSPDVDHIDQVTDDT------------------------------ 454

Query: 713 QTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQG 772
              ++E S KM+ L  L++     G + LVFSQS   L +IE  L  R            
Sbjct: 455 ---LMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNR------------ 499

Query: 773 AQKWVRNISYFRLDGS-TPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRV 831
                 +    R+DG+ T   ERE+ IN F    + +  +FLL+T+ G +G+ L  A RV
Sbjct: 500 ------HFKTLRIDGTVTHLLEREKRINLFQQNKDYS--VFLLTTQVGGVGLTLTAATRV 551

Query: 832 VVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVV-D 890
           V+FD SWNP  DAQAV RVYR GQK+   +YRL+   T+E+KIY RQ+ K  +  +   +
Sbjct: 552 VIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGE 611

Query: 891 DLNPMLNFTRKEVENL 906
             NP   F+++E+  L
Sbjct: 612 KKNPFRYFSKQELREL 627


>gi|58219008 RAD26L hypothetical protein [Homo sapiens]
          Length = 712

 Score =  180 bits (457), Expect = 8e-45
 Identities = 176/642 (27%), Positives = 275/642 (42%), Gaps = 119/642 (18%)

Query: 269 RAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPA 328
           R ++ +Q  G RFLY + +          G GCIL   MGLGKT+QVISF+  +      
Sbjct: 132 RYLRDYQREGTRFLYGHYIH---------GGGCILGDDMGLGKTVQVISFLAAVLHKKGT 182

Query: 329 KTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAK 388
           +  +             E NM    PE L    K E +     K+ ++        +   
Sbjct: 183 REDI-------------ENNM----PEFLLRSMKKEPLSSTAKKMFLI-------VAPLS 218

Query: 389 VMADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRREF 448
           V+ +W  E    L  +  +R+  L  +       + K+R   + +   E  R        
Sbjct: 219 VLYNWKDE----LDTWGYFRVTVLHGNRKDNELIRVKQRKCEIALTTYETLR-------- 266

Query: 449 EKALCRPGPD-----VVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYW 503
              LC    +      VI DE HRIKN +A  ++ +K ++   R+ LTG  LQNN+ E W
Sbjct: 267 ---LCLDELNSLEWSAVIVDEAHRIKNPKARVTEVMKALKCNVRIGLTGTILQNNMKELW 323

Query: 504 CMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRG 563
           C++D+  P  LG+   F   F  P+ +GQ   +T +++   R     L   + G+  RR 
Sbjct: 324 CVMDWAVPGLLGSGTYFKKQFSDPVEHGQRHTATKRELATGRKAMQRLAKKMSGWFLRRT 383

Query: 564 HTVLKIHLPAKEENVILVRLSKIQRDLY---------TQFMDRFRDCGS-SGWLGLNPLK 613
            T++K  LP KE+ ++   L+  Q+ +Y         T  +     C   SG    N   
Sbjct: 384 KTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVTLILQSSEPCTCRSGQKRRN--- 440

Query: 614 AFCVCCKIWNHPDVLYEALQKESLANEQDL--DVEELGSAGTSARCPPQGTKGKGEDSTL 671
               CC   N      + L    L   Q +   V  L +A TS            +  TL
Sbjct: 441 ----CCYKTNSHGETVKTLYLSYLTVLQKVANHVALLQAASTSK-----------QQETL 485

Query: 672 ASSMGEATNSKFLQGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIE 731
              + +   S+F       P   + +    +E   D          + S KM +L  L+ 
Sbjct: 486 IKRICDQVFSRF-------PDFVQKSKDAAFETLSDP---------KYSGKMKVLQQLLN 529

Query: 732 ESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPA 791
              K  DK+L+FS S   L +++++                       + Y RLDGST +
Sbjct: 530 HCRKNRDKVLLFSFSTKLLDVLQQYC------------------MASGLDYRRLDGSTKS 571

Query: 792 FERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVY 851
            ER +++ +FN   ++   + L+ST AG LG+N +GAN VV+FD +WNP +D QA+ R Y
Sbjct: 572 EERLKIVKEFNSTQDVN--ICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAY 629

Query: 852 RYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLN 893
           R GQ +   + RL++  T+E+ +Y RQI KQ +   VV   N
Sbjct: 630 RIGQCRDVKVLRLISLGTVEEIMYLRQIYKQQLHCVVVGSEN 671


>gi|190358534 SWI/SNF-related, matrix-associated actin-dependent
           regulator of chromatin, subfamily a, containing DEAD/H
           box 1 isoform b [Homo sapiens]
          Length = 1026

 Score =  157 bits (397), Expect = 7e-38
 Identities = 154/608 (25%), Positives = 256/608 (42%), Gaps = 119/608 (19%)

Query: 270 AVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAK 329
           ++KP+Q  G+ +L   LV          G   ILA  MGLGKT+Q I+F+  L++     
Sbjct: 496 SLKPYQKVGLNWLA--LVHK-------HGLNGILADEMGLGKTIQAIAFLAYLYQEGNNG 546

Query: 330 TVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAKV 389
             L +VP +T+ NWL E N+W P  + L      EE +   F +H          SR   
Sbjct: 547 PHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIH----------SR--- 593

Query: 390 MADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFE 449
                         YE Y ++    + A                 +   D +  FRR   
Sbjct: 594 --------------YEDYNVIVTTYNCA-----------------ISSSDDRSLFRRL-- 620

Query: 450 KALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFV 509
                   +  I DEGH +KN  +   Q L  I +  R++LTG P+QNNL+E   +++FV
Sbjct: 621 ------KLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFV 674

Query: 510 RPD-FLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHS--LLEGFVQRRGHTV 566
            P  F  +  E   MF     +         D + +  +  + H+  +++ F+ RR    
Sbjct: 675 MPHMFSSSTSEIRRMFSSKTKSA--------DEQSIYEKERIAHAKQIIKPFILRRVKEE 726

Query: 567 LKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPD 626
           +   LP K++ + L  +S+ Q  LY    +R +   ++               K+ NHP 
Sbjct: 727 VLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLEKNTEMCNVMMQLRKMANHPL 786

Query: 627 VLYEALQKESLANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQG 686
           +  +    E L     L ++E              T  +     +   M   T+ +    
Sbjct: 787 LHRQYYTAEKLKEMSQLMLKE-------------PTHCEANPDLIFEDMEVMTDFEL--- 830

Query: 687 VGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQS 746
              +   ++  +I  ++   DL+ +        S K  +L  ++ E  + GD++++FSQ 
Sbjct: 831 ---HVLCKQYRHINNFQLDMDLILD--------SGKFRVLGCILSELKQKGDRVVLFSQF 879

Query: 747 LSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSN 806
              L ++E  L   +                    Y RLDG T   ER  LI++FN  ++
Sbjct: 880 TMMLDILEVLLKHHQH------------------RYLRLDGKTQISERIHLIDEFN--TD 919

Query: 807 LTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVA 866
           +  ++FLLST+AG LG+NL  AN V++ D   NP +D QA  R +R GQ K   + +L++
Sbjct: 920 MDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLIS 979

Query: 867 DYTLEKKI 874
             T+E+ +
Sbjct: 980 QGTIEESM 987


>gi|190358536 SWI/SNF-related, matrix-associated actin-dependent
           regulator of chromatin, subfamily a, containing DEAD/H
           box 1 isoform a [Homo sapiens]
          Length = 1028

 Score =  154 bits (389), Expect = 6e-37
 Identities = 155/610 (25%), Positives = 257/610 (42%), Gaps = 121/610 (19%)

Query: 270 AVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAK 329
           ++KP+Q  G+ +L   LV          G   ILA  MGLGKT+Q I+F+  L++     
Sbjct: 496 SLKPYQKVGLNWLA--LVHK-------HGLNGILADEMGLGKTIQAIAFLAYLYQEGNNG 546

Query: 330 TVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAKV 389
             L +VP +T+ NWL E N+W P  + L      EE +   F +H          SR   
Sbjct: 547 PHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIH----------SR--- 593

Query: 390 MADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFE 449
                         YE Y ++    + A                 +   D +  FRR   
Sbjct: 594 --------------YEDYNVIVTTYNCA-----------------ISSSDDRSLFRRL-- 620

Query: 450 KALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFV 509
                   +  I DEGH +KN  +   Q L  I +  R++LTG P+QNNL+E   +++FV
Sbjct: 621 ------KLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFV 674

Query: 510 RPD-FLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHS--LLEGFVQRRGHTV 566
            P  F  +  E   MF     +         D + +  +  + H+  +++ F+ RR    
Sbjct: 675 MPHMFSSSTSEIRRMFSSKTKSA--------DEQSIYEKERIAHAKQIIKPFILRRVKEE 726

Query: 567 LKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNP--LKAFCVCCKIWNH 624
           +   LP K++ + L  +S+ Q  LY    +R +   ++     N           K+ NH
Sbjct: 727 VLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANH 786

Query: 625 PDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFL 684
           P +  +    E L     L ++E              T  +     +   M   T+ +  
Sbjct: 787 PLLHRQYYTAEKLKEMSQLMLKE-------------PTHCEANPDLIFEDMEVMTDFEL- 832

Query: 685 QGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFS 744
                +   ++  +I  ++   DL+ +        S K  +L  ++ E  + GD++++FS
Sbjct: 833 -----HVLCKQYRHINNFQLDMDLILD--------SGKFRVLGCILSELKQKGDRVVLFS 879

Query: 745 QSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDP 804
           Q    L ++E  L   +                    Y RLDG T   ER  LI++FN  
Sbjct: 880 QFTMMLDILEVLLKHHQH------------------RYLRLDGKTQISERIHLIDEFN-- 919

Query: 805 SNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRL 864
           +++  ++FLLST+AG LG+NL  AN V++ D   NP +D QA  R +R GQ K   + +L
Sbjct: 920 TDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKL 979

Query: 865 VADYTLEKKI 874
           ++  T+E+ +
Sbjct: 980 ISQGTIEESM 989


>gi|190358532 SWI/SNF-related, matrix-associated actin-dependent
           regulator of chromatin, subfamily a, containing DEAD/H
           box 1 isoform a [Homo sapiens]
          Length = 1028

 Score =  154 bits (389), Expect = 6e-37
 Identities = 155/610 (25%), Positives = 257/610 (42%), Gaps = 121/610 (19%)

Query: 270 AVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAK 329
           ++KP+Q  G+ +L   LV          G   ILA  MGLGKT+Q I+F+  L++     
Sbjct: 496 SLKPYQKVGLNWLA--LVHK-------HGLNGILADEMGLGKTIQAIAFLAYLYQEGNNG 546

Query: 330 TVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAKV 389
             L +VP +T+ NWL E N+W P  + L      EE +   F +H          SR   
Sbjct: 547 PHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIH----------SR--- 593

Query: 390 MADWVSEGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFE 449
                         YE Y ++    + A                 +   D +  FRR   
Sbjct: 594 --------------YEDYNVIVTTYNCA-----------------ISSSDDRSLFRRL-- 620

Query: 450 KALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFV 509
                   +  I DEGH +KN  +   Q L  I +  R++LTG P+QNNL+E   +++FV
Sbjct: 621 ------KLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFV 674

Query: 510 RPD-FLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHS--LLEGFVQRRGHTV 566
            P  F  +  E   MF     +         D + +  +  + H+  +++ F+ RR    
Sbjct: 675 MPHMFSSSTSEIRRMFSSKTKSA--------DEQSIYEKERIAHAKQIIKPFILRRVKEE 726

Query: 567 LKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNP--LKAFCVCCKIWNH 624
           +   LP K++ + L  +S+ Q  LY    +R +   ++     N           K+ NH
Sbjct: 727 VLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANH 786

Query: 625 PDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFL 684
           P +  +    E L     L ++E              T  +     +   M   T+ +  
Sbjct: 787 PLLHRQYYTAEKLKEMSQLMLKE-------------PTHCEANPDLIFEDMEVMTDFEL- 832

Query: 685 QGVGFNPFQERGNNIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFS 744
                +   ++  +I  ++   DL+ +        S K  +L  ++ E  + GD++++FS
Sbjct: 833 -----HVLCKQYRHINNFQLDMDLILD--------SGKFRVLGCILSELKQKGDRVVLFS 879

Query: 745 QSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDP 804
           Q    L ++E  L   +                    Y RLDG T   ER  LI++FN  
Sbjct: 880 QFTMMLDILEVLLKHHQH------------------RYLRLDGKTQISERIHLIDEFN-- 919

Query: 805 SNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRL 864
           +++  ++FLLST+AG LG+NL  AN V++ D   NP +D QA  R +R GQ K   + +L
Sbjct: 920 TDMDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKL 979

Query: 865 VADYTLEKKI 874
           ++  T+E+ +
Sbjct: 980 ISQGTIEESM 989


>gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription
            factor-associated, 170kDa [Homo sapiens]
          Length = 1849

 Score =  151 bits (381), Expect = 5e-36
 Identities = 131/486 (26%), Positives = 211/486 (43%), Gaps = 88/486 (18%)

Query: 426  KRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSR 485
            KR + ++   D      +F R  +   C       I DEGH IKN +   S+A+K + + 
Sbjct: 1374 KRHNLIVASYDVVRNDIDFFRNIKFNYC-------ILDEGHVIKNGKTKLSKAVKQLTAN 1426

Query: 486  RRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMR 545
             R++L+G P+QNN++E W + DF+ P FLGT ++F+  + +PIL  +   S+ ++     
Sbjct: 1427 YRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGV 1486

Query: 546  YRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRDCGSSG 605
                 LH  +  F+ RR            +E+V+     KI +D Y              
Sbjct: 1487 LAMDALHRQVLPFLLRR-----------MKEDVLQDLPPKIIQDYYCT------------ 1523

Query: 606  WLGLNPLKAFCVCCKIWNHPDVLYEALQKESLANEQDLDVEELGSAGTSARCPPQGTKGK 665
               L+PL+              LYE   K     + D   E + SA  S        K  
Sbjct: 1524 ---LSPLQV------------QLYEDFAKSRAKCDVD---ETVSSATLSEETEKPKLKAT 1565

Query: 666  GEDSTLASSMGEATNSKFLQGVGFNP-FQERGNNIVTYEWAKDLLTNYQTGVLENSPKMV 724
            G        + +  N   L     +P F+     +         + N     ++++PK+ 
Sbjct: 1566 GHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLA--------VQNSSLHDIQHAPKLS 1617

Query: 725  LLFHLI--------------EESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEG 770
             L  L+               ESV    +IL+F Q  S L ++E  L K  +P       
Sbjct: 1618 ALKQLLLDCGLGNGSTSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLP------- 1670

Query: 771  QGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANR 830
                    +++Y RLDGS P  +R  ++++FN+  ++   + LL+T  G LG+NL GA+ 
Sbjct: 1671 --------SVTYLRLDGSIPPGQRHSIVSRFNNDPSID--VLLLTTHVGGLGLNLTGADT 1720

Query: 831  VVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVD 890
            VV  +  WNP  D QA+ R +R GQK+   +YRL+   TLE+KI   Q  K  +++ V+ 
Sbjct: 1721 VVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVIS 1780

Query: 891  DLNPML 896
              N  L
Sbjct: 1781 QENSSL 1786


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score =  139 bits (349), Expect = 3e-32
 Identities = 119/445 (26%), Positives = 199/445 (44%), Gaps = 103/445 (23%)

Query: 460  VICDEGHRIKNCQASTSQALK-NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQ 518
            +I DEGHR+KN     +Q L  +  + RR++LTG PLQN L E W +++F+ P    +  
Sbjct: 848  MIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCS 907

Query: 519  EFSNMFERPI-LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEEN 577
             F   F  P  + G+ +D   ++  L+  R   LH +L  F+ RR    ++  LP K E 
Sbjct: 908  TFEQWFNAPFAMTGERVDLNEEETILIIRR---LHKVLRPFLLRRLKKEVESQLPEKVEY 964

Query: 578  VILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESL 637
            VI   +S +Q+                                      +LY  +Q + +
Sbjct: 965  VIKCDMSALQK--------------------------------------ILYRHMQAKGI 986

Query: 638  ANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGN 697
                  + ++               KGKG   TL +++ +      L+ +  +P+  +  
Sbjct: 987  LLTDGSEKDK---------------KGKGGAKTLMNTIMQ------LRKICNHPYMFQH- 1024

Query: 698  NIVTYEWAKDLLTNYQTGVLEN------SPKMVLLFHLIEESVKLGDKILVFSQSLSTLA 751
              +   +A+ L   Y  GV+        S K  LL  ++ +      ++L+F Q  S + 
Sbjct: 1025 --IEESFAEHL--GYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT 1080

Query: 752  LIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWL 811
            ++E++                     RN  Y RLDG+T + +R  L+ +FN+P +   ++
Sbjct: 1081 IMEDYFA------------------FRNFLYLRLDGTTKSEDRAALLKKFNEPGS-QYFI 1121

Query: 812  FLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLE 871
            FLLSTRAG LG+NL  A+ VV+FD+ WNP  D QA  R +R GQ+    + RL    ++E
Sbjct: 1122 FLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1181

Query: 872  KKI---------YDRQISKQGMSDR 887
            +KI          D+++ + GM D+
Sbjct: 1182 EKILAAAKYKLNVDQKVIQAGMFDQ 1206



 Score = 64.3 bits (155), Expect = 8e-10
 Identities = 72/277 (25%), Positives = 120/277 (43%), Gaps = 38/277 (13%)

Query: 88  HQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKDY 147
           H+    A E  K++R +K +       +       EP+ +++Q  +L  +    +  K  
Sbjct: 547 HKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVL 606

Query: 148 AAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSG 207
             P      +    +  L  + G ++ PR  ++E    D     E+E+SSR E       
Sbjct: 607 FGPEAPKASQL---DAWLEMNPGYEVAPRSDSEESDS-DYEEEDEEEESSRQET------ 656

Query: 208 EEDTLHIVDSSESVSEDDEEE--EKGGTHVNDVLN-QRDALGR-----VLVNLNHPPEEE 259
            E+ + +  +SE VSE D ++  E     V+D  + Q  A G      V   ++   E++
Sbjct: 657 -EEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQ 715

Query: 260 NVFLAPQLARAVKPHQIGGIRF---LYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVI 316
           +  L   +   +K +Q+ G+ +   LY+N +              ILA  MGLGKT+Q I
Sbjct: 716 SALL---INGTLKHYQLQGLEWMVSLYNNNLNG------------ILADEMGLGKTIQTI 760

Query: 317 SFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLP 352
           + I  L  H       L IVP++TL NW  EF+ W P
Sbjct: 761 ALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAP 797



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 17/154 (11%)

Query: 1    MSDESASGSDPDLDPDVELEDAEEEEEEEEVAVEE------CDRDDEEDLLDDPSLEGMC 54
            M D+ +S  +        LE  EE EEE+EV  +E        R++E DL     ++   
Sbjct: 1203 MFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMD--- 1259

Query: 55   GTEHAQLGEDGQQPPRCTSTTSSQSEPSEQLRRH-QGKNLASEDPKKKRAQKPSHMRRNI 113
                 +  ED + P R          PS  ++   + + L  E+ ++K   + S  RR++
Sbjct: 1260 -----RRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDV 1314

Query: 114  --RKLLREDQLEPVTKAAQQEELERRKRLEQQRK 145
                 L E Q     +    EE+E   RL+++++
Sbjct: 1315 DYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKR 1348


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score =  139 bits (349), Expect = 3e-32
 Identities = 119/445 (26%), Positives = 199/445 (44%), Gaps = 103/445 (23%)

Query: 460  VICDEGHRIKNCQASTSQALK-NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQ 518
            +I DEGHR+KN     +Q L  +  + RR++LTG PLQN L E W +++F+ P    +  
Sbjct: 848  MIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCS 907

Query: 519  EFSNMFERPI-LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEEN 577
             F   F  P  + G+ +D   ++  L+  R   LH +L  F+ RR    ++  LP K E 
Sbjct: 908  TFEQWFNAPFAMTGERVDLNEEETILIIRR---LHKVLRPFLLRRLKKEVESQLPEKVEY 964

Query: 578  VILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESL 637
            VI   +S +Q+                                      +LY  +Q + +
Sbjct: 965  VIKCDMSALQK--------------------------------------ILYRHMQAKGI 986

Query: 638  ANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGN 697
                  + ++               KGKG   TL +++ +      L+ +  +P+  +  
Sbjct: 987  LLTDGSEKDK---------------KGKGGAKTLMNTIMQ------LRKICNHPYMFQH- 1024

Query: 698  NIVTYEWAKDLLTNYQTGVLEN------SPKMVLLFHLIEESVKLGDKILVFSQSLSTLA 751
              +   +A+ L   Y  GV+        S K  LL  ++ +      ++L+F Q  S + 
Sbjct: 1025 --IEESFAEHL--GYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTSLMT 1080

Query: 752  LIEEFLGKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWL 811
            ++E++                     RN  Y RLDG+T + +R  L+ +FN+P +   ++
Sbjct: 1081 IMEDYFA------------------FRNFLYLRLDGTTKSEDRAALLKKFNEPGS-QYFI 1121

Query: 812  FLLSTRAGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLE 871
            FLLSTRAG LG+NL  A+ VV+FD+ WNP  D QA  R +R GQ+    + RL    ++E
Sbjct: 1122 FLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVE 1181

Query: 872  KKI---------YDRQISKQGMSDR 887
            +KI          D+++ + GM D+
Sbjct: 1182 EKILAAAKYKLNVDQKVIQAGMFDQ 1206



 Score = 64.3 bits (155), Expect = 8e-10
 Identities = 72/277 (25%), Positives = 120/277 (43%), Gaps = 38/277 (13%)

Query: 88  HQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLEQQRKDY 147
           H+    A E  K++R +K +       +       EP+ +++Q  +L  +    +  K  
Sbjct: 547 HKQAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVL 606

Query: 148 AAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSG 207
             P      +    +  L  + G ++ PR  ++E    D     E+E+SSR E       
Sbjct: 607 FGPEAPKASQL---DAWLEMNPGYEVAPRSDSEESDS-DYEEEDEEEESSRQET------ 656

Query: 208 EEDTLHIVDSSESVSEDDEEE--EKGGTHVNDVLN-QRDALGR-----VLVNLNHPPEEE 259
            E+ + +  +SE VSE D ++  E     V+D  + Q  A G      V   ++   E++
Sbjct: 657 -EEKILLDPNSEEVSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQ 715

Query: 260 NVFLAPQLARAVKPHQIGGIRF---LYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVI 316
           +  L   +   +K +Q+ G+ +   LY+N +              ILA  MGLGKT+Q I
Sbjct: 716 SALL---INGTLKHYQLQGLEWMVSLYNNNLNG------------ILADEMGLGKTIQTI 760

Query: 317 SFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLP 352
           + I  L  H       L IVP++TL NW  EF+ W P
Sbjct: 761 ALITYLMEHKRLNGPYLIIVPLSTLSNWTYEFDKWAP 797



 Score = 33.9 bits (76), Expect = 1.2
 Identities = 37/154 (24%), Positives = 65/154 (42%), Gaps = 17/154 (11%)

Query: 1    MSDESASGSDPDLDPDVELEDAEEEEEEEEVAVEE------CDRDDEEDLLDDPSLEGMC 54
            M D+ +S  +        LE  EE EEE+EV  +E        R++E DL     ++   
Sbjct: 1203 MFDQKSSSHERRAFLQAILEHEEENEEEDEVPDDETLNQMIARREEEFDLFMRMDMD--- 1259

Query: 55   GTEHAQLGEDGQQPPRCTSTTSSQSEPSEQLRRH-QGKNLASEDPKKKRAQKPSHMRRNI 113
                 +  ED + P R          PS  ++   + + L  E+ ++K   + S  RR++
Sbjct: 1260 -----RRREDARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKIFGRGSRQRRDV 1314

Query: 114  --RKLLREDQLEPVTKAAQQEELERRKRLEQQRK 145
                 L E Q     +    EE+E   RL+++++
Sbjct: 1315 DYSDALTEKQWLRAIEDGNLEEMEEEVRLKKRKR 1348


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score =  123 bits (309), Expect = 1e-27
 Identities = 109/439 (24%), Positives = 186/439 (42%), Gaps = 91/439 (20%)

Query: 460  VICDEGHRIKNCQASTSQALK-NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQ 518
            +I DEGHR+KN     +Q L  +  + RR++LTG PLQN L E W +++F+ P    +  
Sbjct: 878  MIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCS 937

Query: 519  EFSNMFERPI-LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEEN 577
             F   F  P  + G+ +D   ++  L+  R   LH +L  F+ R                
Sbjct: 938  TFEQWFNAPFAMTGEKVDLNEEETILIIRR---LHKVLRPFLLR---------------- 978

Query: 578  VILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESL 637
                   ++++++  Q  ++                 + + C +     VLY  +Q + +
Sbjct: 979  -------RLKKEVEAQLPEKVE---------------YVIKCDMSALQRVLYRHMQAKGV 1016

Query: 638  ANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGN 697
                  + ++ G  GT        T  +         M +     F + +GF     +G 
Sbjct: 1017 LLTDGSEKDKKGKGGTKTL---MNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGL 1073

Query: 698  NIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFL 757
            ++                    S K  LL  ++ +      K+L+F Q  S + ++E++ 
Sbjct: 1074 DLY-----------------RASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYF 1116

Query: 758  GKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTR 817
                                R   Y RLDG+T A +R  L+  FN+P +   ++FLLSTR
Sbjct: 1117 A------------------YRGFKYLRLDGTTKAEDRGMLLKTFNEPGS-EYFIFLLSTR 1157

Query: 818  AGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKI--- 874
            AG LG+NL  A+ V++FD+ WNP  D QA  R +R GQ+    + RL    ++E+KI   
Sbjct: 1158 AGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAA 1217

Query: 875  ------YDRQISKQGMSDR 887
                   D+++ + GM D+
Sbjct: 1218 AKYKLNVDQKVIQAGMFDQ 1236



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 74/285 (25%), Positives = 120/285 (42%), Gaps = 36/285 (12%)

Query: 82  SEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLE 141
           +E +R+H+   +A E  KKK+ +K  +       +  +   EP+ + +Q  +L  +    
Sbjct: 565 TELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDG--EPLDETSQMSDLPVKVIHV 622

Query: 142 QQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEV 201
           +  K           +    E  L  + G ++ PR  ++E       SGSE+E+   +E 
Sbjct: 623 ESGKILTGTDAPKAGQL---EAWLEMNPGYEVAPRSDSEE-------SGSEEEEEEEEEE 672

Query: 202 IELSSGEEDTLHIVDS-------SESVSEDDEEE--EKGGTHVNDVLNQRDALGRVLVNL 252
            +  + +  TL + +        S+ VSE D     E     V+D      AL R L + 
Sbjct: 673 -QPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSY 731

Query: 253 ----NHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMG 308
               +   E  +   A  +   +K +QI G+ +L      +L           ILA  MG
Sbjct: 732 YAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNG---------ILADEMG 782

Query: 309 LGKTLQVISFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLP 352
           LGKT+Q I+ I  L  H       L IVP++TL NW  EF+ W P
Sbjct: 783 LGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAP 827


>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform F [Homo sapiens]
          Length = 1613

 Score =  123 bits (309), Expect = 1e-27
 Identities = 109/439 (24%), Positives = 186/439 (42%), Gaps = 91/439 (20%)

Query: 460  VICDEGHRIKNCQASTSQALK-NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQ 518
            +I DEGHR+KN     +Q L  +  + RR++LTG PLQN L E W +++F+ P    +  
Sbjct: 878  MIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCS 937

Query: 519  EFSNMFERPI-LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEEN 577
             F   F  P  + G+ +D   ++  L+  R   LH +L  F+ R                
Sbjct: 938  TFEQWFNAPFAMTGEKVDLNEEETILIIRR---LHKVLRPFLLR---------------- 978

Query: 578  VILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESL 637
                   ++++++  Q  ++                 + + C +     VLY  +Q + +
Sbjct: 979  -------RLKKEVEAQLPEKVE---------------YVIKCDMSALQRVLYRHMQAKGV 1016

Query: 638  ANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGN 697
                  + ++ G  GT        T  +         M +     F + +GF     +G 
Sbjct: 1017 LLTDGSEKDKKGKGGTKTL---MNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGL 1073

Query: 698  NIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFL 757
            ++                    S K  LL  ++ +      K+L+F Q  S + ++E++ 
Sbjct: 1074 DLY-----------------RASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYF 1116

Query: 758  GKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTR 817
                                R   Y RLDG+T A +R  L+  FN+P +   ++FLLSTR
Sbjct: 1117 A------------------YRGFKYLRLDGTTKAEDRGMLLKTFNEPGS-EYFIFLLSTR 1157

Query: 818  AGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKI--- 874
            AG LG+NL  A+ V++FD+ WNP  D QA  R +R GQ+    + RL    ++E+KI   
Sbjct: 1158 AGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAA 1217

Query: 875  ------YDRQISKQGMSDR 887
                   D+++ + GM D+
Sbjct: 1218 AKYKLNVDQKVIQAGMFDQ 1236



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 74/285 (25%), Positives = 120/285 (42%), Gaps = 36/285 (12%)

Query: 82  SEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLE 141
           +E +R+H+   +A E  KKK+ +K  +       +  +   EP+ + +Q  +L  +    
Sbjct: 565 TELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDG--EPLDETSQMSDLPVKVIHV 622

Query: 142 QQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEV 201
           +  K           +    E  L  + G ++ PR  ++E       SGSE+E+   +E 
Sbjct: 623 ESGKILTGTDAPKAGQL---EAWLEMNPGYEVAPRSDSEE-------SGSEEEEEEEEEE 672

Query: 202 IELSSGEEDTLHIVDS-------SESVSEDDEEE--EKGGTHVNDVLNQRDALGRVLVNL 252
            +  + +  TL + +        S+ VSE D     E     V+D      AL R L + 
Sbjct: 673 -QPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSY 731

Query: 253 ----NHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMG 308
               +   E  +   A  +   +K +QI G+ +L      +L           ILA  MG
Sbjct: 732 YAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNG---------ILADEMG 782

Query: 309 LGKTLQVISFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLP 352
           LGKT+Q I+ I  L  H       L IVP++TL NW  EF+ W P
Sbjct: 783 LGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAP 827


>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform E [Homo sapiens]
          Length = 1614

 Score =  123 bits (309), Expect = 1e-27
 Identities = 109/439 (24%), Positives = 186/439 (42%), Gaps = 91/439 (20%)

Query: 460  VICDEGHRIKNCQASTSQALK-NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQ 518
            +I DEGHR+KN     +Q L  +  + RR++LTG PLQN L E W +++F+ P    +  
Sbjct: 878  MIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCS 937

Query: 519  EFSNMFERPI-LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEEN 577
             F   F  P  + G+ +D   ++  L+  R   LH +L  F+ R                
Sbjct: 938  TFEQWFNAPFAMTGEKVDLNEEETILIIRR---LHKVLRPFLLR---------------- 978

Query: 578  VILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESL 637
                   ++++++  Q  ++                 + + C +     VLY  +Q + +
Sbjct: 979  -------RLKKEVEAQLPEKVE---------------YVIKCDMSALQRVLYRHMQAKGV 1016

Query: 638  ANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGN 697
                  + ++ G  GT        T  +         M +     F + +GF     +G 
Sbjct: 1017 LLTDGSEKDKKGKGGTKTL---MNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGL 1073

Query: 698  NIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFL 757
            ++                    S K  LL  ++ +      K+L+F Q  S + ++E++ 
Sbjct: 1074 DLY-----------------RASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYF 1116

Query: 758  GKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTR 817
                                R   Y RLDG+T A +R  L+  FN+P +   ++FLLSTR
Sbjct: 1117 A------------------YRGFKYLRLDGTTKAEDRGMLLKTFNEPGS-EYFIFLLSTR 1157

Query: 818  AGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKI--- 874
            AG LG+NL  A+ V++FD+ WNP  D QA  R +R GQ+    + RL    ++E+KI   
Sbjct: 1158 AGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAA 1217

Query: 875  ------YDRQISKQGMSDR 887
                   D+++ + GM D+
Sbjct: 1218 AKYKLNVDQKVIQAGMFDQ 1236



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 74/285 (25%), Positives = 120/285 (42%), Gaps = 36/285 (12%)

Query: 82  SEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLE 141
           +E +R+H+   +A E  KKK+ +K  +       +  +   EP+ + +Q  +L  +    
Sbjct: 565 TELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDG--EPLDETSQMSDLPVKVIHV 622

Query: 142 QQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEV 201
           +  K           +    E  L  + G ++ PR  ++E       SGSE+E+   +E 
Sbjct: 623 ESGKILTGTDAPKAGQL---EAWLEMNPGYEVAPRSDSEE-------SGSEEEEEEEEEE 672

Query: 202 IELSSGEEDTLHIVDS-------SESVSEDDEEE--EKGGTHVNDVLNQRDALGRVLVNL 252
            +  + +  TL + +        S+ VSE D     E     V+D      AL R L + 
Sbjct: 673 -QPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSY 731

Query: 253 ----NHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMG 308
               +   E  +   A  +   +K +QI G+ +L      +L           ILA  MG
Sbjct: 732 YAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNG---------ILADEMG 782

Query: 309 LGKTLQVISFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLP 352
           LGKT+Q I+ I  L  H       L IVP++TL NW  EF+ W P
Sbjct: 783 LGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAP 827


>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform D [Homo sapiens]
          Length = 1616

 Score =  123 bits (309), Expect = 1e-27
 Identities = 109/439 (24%), Positives = 186/439 (42%), Gaps = 91/439 (20%)

Query: 460  VICDEGHRIKNCQASTSQALK-NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQ 518
            +I DEGHR+KN     +Q L  +  + RR++LTG PLQN L E W +++F+ P    +  
Sbjct: 878  MIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCS 937

Query: 519  EFSNMFERPI-LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEEN 577
             F   F  P  + G+ +D   ++  L+  R   LH +L  F+ R                
Sbjct: 938  TFEQWFNAPFAMTGEKVDLNEEETILIIRR---LHKVLRPFLLR---------------- 978

Query: 578  VILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESL 637
                   ++++++  Q  ++                 + + C +     VLY  +Q + +
Sbjct: 979  -------RLKKEVEAQLPEKVE---------------YVIKCDMSALQRVLYRHMQAKGV 1016

Query: 638  ANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGN 697
                  + ++ G  GT        T  +         M +     F + +GF     +G 
Sbjct: 1017 LLTDGSEKDKKGKGGTKTL---MNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGL 1073

Query: 698  NIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFL 757
            ++                    S K  LL  ++ +      K+L+F Q  S + ++E++ 
Sbjct: 1074 DLY-----------------RASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYF 1116

Query: 758  GKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTR 817
                                R   Y RLDG+T A +R  L+  FN+P +   ++FLLSTR
Sbjct: 1117 A------------------YRGFKYLRLDGTTKAEDRGMLLKTFNEPGS-EYFIFLLSTR 1157

Query: 818  AGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKI--- 874
            AG LG+NL  A+ V++FD+ WNP  D QA  R +R GQ+    + RL    ++E+KI   
Sbjct: 1158 AGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAA 1217

Query: 875  ------YDRQISKQGMSDR 887
                   D+++ + GM D+
Sbjct: 1218 AKYKLNVDQKVIQAGMFDQ 1236



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 74/285 (25%), Positives = 120/285 (42%), Gaps = 36/285 (12%)

Query: 82  SEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLE 141
           +E +R+H+   +A E  KKK+ +K  +       +  +   EP+ + +Q  +L  +    
Sbjct: 565 TELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDG--EPLDETSQMSDLPVKVIHV 622

Query: 142 QQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEV 201
           +  K           +    E  L  + G ++ PR  ++E       SGSE+E+   +E 
Sbjct: 623 ESGKILTGTDAPKAGQL---EAWLEMNPGYEVAPRSDSEE-------SGSEEEEEEEEEE 672

Query: 202 IELSSGEEDTLHIVDS-------SESVSEDDEEE--EKGGTHVNDVLNQRDALGRVLVNL 252
            +  + +  TL + +        S+ VSE D     E     V+D      AL R L + 
Sbjct: 673 -QPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSY 731

Query: 253 ----NHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMG 308
               +   E  +   A  +   +K +QI G+ +L      +L           ILA  MG
Sbjct: 732 YAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNG---------ILADEMG 782

Query: 309 LGKTLQVISFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLP 352
           LGKT+Q I+ I  L  H       L IVP++TL NW  EF+ W P
Sbjct: 783 LGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAP 827


>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform C [Homo sapiens]
          Length = 1617

 Score =  123 bits (309), Expect = 1e-27
 Identities = 109/439 (24%), Positives = 186/439 (42%), Gaps = 91/439 (20%)

Query: 460  VICDEGHRIKNCQASTSQALK-NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQ 518
            +I DEGHR+KN     +Q L  +  + RR++LTG PLQN L E W +++F+ P    +  
Sbjct: 878  MIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCS 937

Query: 519  EFSNMFERPI-LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEEN 577
             F   F  P  + G+ +D   ++  L+  R   LH +L  F+ R                
Sbjct: 938  TFEQWFNAPFAMTGEKVDLNEEETILIIRR---LHKVLRPFLLR---------------- 978

Query: 578  VILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESL 637
                   ++++++  Q  ++                 + + C +     VLY  +Q + +
Sbjct: 979  -------RLKKEVEAQLPEKVE---------------YVIKCDMSALQRVLYRHMQAKGV 1016

Query: 638  ANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGN 697
                  + ++ G  GT        T  +         M +     F + +GF     +G 
Sbjct: 1017 LLTDGSEKDKKGKGGTKTL---MNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGL 1073

Query: 698  NIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFL 757
            ++                    S K  LL  ++ +      K+L+F Q  S + ++E++ 
Sbjct: 1074 DLY-----------------RASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYF 1116

Query: 758  GKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTR 817
                                R   Y RLDG+T A +R  L+  FN+P +   ++FLLSTR
Sbjct: 1117 A------------------YRGFKYLRLDGTTKAEDRGMLLKTFNEPGS-EYFIFLLSTR 1157

Query: 818  AGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKI--- 874
            AG LG+NL  A+ V++FD+ WNP  D QA  R +R GQ+    + RL    ++E+KI   
Sbjct: 1158 AGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAA 1217

Query: 875  ------YDRQISKQGMSDR 887
                   D+++ + GM D+
Sbjct: 1218 AKYKLNVDQKVIQAGMFDQ 1236



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 74/285 (25%), Positives = 120/285 (42%), Gaps = 36/285 (12%)

Query: 82  SEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLE 141
           +E +R+H+   +A E  KKK+ +K  +       +  +   EP+ + +Q  +L  +    
Sbjct: 565 TELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDG--EPLDETSQMSDLPVKVIHV 622

Query: 142 QQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEV 201
           +  K           +    E  L  + G ++ PR  ++E       SGSE+E+   +E 
Sbjct: 623 ESGKILTGTDAPKAGQL---EAWLEMNPGYEVAPRSDSEE-------SGSEEEEEEEEEE 672

Query: 202 IELSSGEEDTLHIVDS-------SESVSEDDEEE--EKGGTHVNDVLNQRDALGRVLVNL 252
            +  + +  TL + +        S+ VSE D     E     V+D      AL R L + 
Sbjct: 673 -QPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSY 731

Query: 253 ----NHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMG 308
               +   E  +   A  +   +K +QI G+ +L      +L           ILA  MG
Sbjct: 732 YAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNG---------ILADEMG 782

Query: 309 LGKTLQVISFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLP 352
           LGKT+Q I+ I  L  H       L IVP++TL NW  EF+ W P
Sbjct: 783 LGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAP 827


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score =  123 bits (309), Expect = 1e-27
 Identities = 109/439 (24%), Positives = 186/439 (42%), Gaps = 91/439 (20%)

Query: 460  VICDEGHRIKNCQASTSQALK-NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQ 518
            +I DEGHR+KN     +Q L  +  + RR++LTG PLQN L E W +++F+ P    +  
Sbjct: 878  MIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCS 937

Query: 519  EFSNMFERPI-LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEEN 577
             F   F  P  + G+ +D   ++  L+  R   LH +L  F+ R                
Sbjct: 938  TFEQWFNAPFAMTGEKVDLNEEETILIIRR---LHKVLRPFLLR---------------- 978

Query: 578  VILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESL 637
                   ++++++  Q  ++                 + + C +     VLY  +Q + +
Sbjct: 979  -------RLKKEVEAQLPEKVE---------------YVIKCDMSALQRVLYRHMQAKGV 1016

Query: 638  ANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGN 697
                  + ++ G  GT        T  +         M +     F + +GF     +G 
Sbjct: 1017 LLTDGSEKDKKGKGGTKTL---MNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGL 1073

Query: 698  NIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFL 757
            ++                    S K  LL  ++ +      K+L+F Q  S + ++E++ 
Sbjct: 1074 DLY-----------------RASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYF 1116

Query: 758  GKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTR 817
                                R   Y RLDG+T A +R  L+  FN+P +   ++FLLSTR
Sbjct: 1117 A------------------YRGFKYLRLDGTTKAEDRGMLLKTFNEPGS-EYFIFLLSTR 1157

Query: 818  AGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKI--- 874
            AG LG+NL  A+ V++FD+ WNP  D QA  R +R GQ+    + RL    ++E+KI   
Sbjct: 1158 AGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAA 1217

Query: 875  ------YDRQISKQGMSDR 887
                   D+++ + GM D+
Sbjct: 1218 AKYKLNVDQKVIQAGMFDQ 1236



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 74/285 (25%), Positives = 120/285 (42%), Gaps = 36/285 (12%)

Query: 82  SEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLE 141
           +E +R+H+   +A E  KKK+ +K  +       +  +   EP+ + +Q  +L  +    
Sbjct: 565 TELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDG--EPLDETSQMSDLPVKVIHV 622

Query: 142 QQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEV 201
           +  K           +    E  L  + G ++ PR  ++E       SGSE+E+   +E 
Sbjct: 623 ESGKILTGTDAPKAGQL---EAWLEMNPGYEVAPRSDSEE-------SGSEEEEEEEEEE 672

Query: 202 IELSSGEEDTLHIVDS-------SESVSEDDEEE--EKGGTHVNDVLNQRDALGRVLVNL 252
            +  + +  TL + +        S+ VSE D     E     V+D      AL R L + 
Sbjct: 673 -QPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSY 731

Query: 253 ----NHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMG 308
               +   E  +   A  +   +K +QI G+ +L      +L           ILA  MG
Sbjct: 732 YAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNG---------ILADEMG 782

Query: 309 LGKTLQVISFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLP 352
           LGKT+Q I+ I  L  H       L IVP++TL NW  EF+ W P
Sbjct: 783 LGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAP 827


>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score =  123 bits (309), Expect = 1e-27
 Identities = 109/439 (24%), Positives = 186/439 (42%), Gaps = 91/439 (20%)

Query: 460  VICDEGHRIKNCQASTSQALK-NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQ 518
            +I DEGHR+KN     +Q L  +  + RR++LTG PLQN L E W +++F+ P    +  
Sbjct: 878  MIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCS 937

Query: 519  EFSNMFERPI-LNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEEN 577
             F   F  P  + G+ +D   ++  L+  R   LH +L  F+ R                
Sbjct: 938  TFEQWFNAPFAMTGEKVDLNEEETILIIRR---LHKVLRPFLLR---------------- 978

Query: 578  VILVRLSKIQRDLYTQFMDRFRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQKESL 637
                   ++++++  Q  ++                 + + C +     VLY  +Q + +
Sbjct: 979  -------RLKKEVEAQLPEKVE---------------YVIKCDMSALQRVLYRHMQAKGV 1016

Query: 638  ANEQDLDVEELGSAGTSARCPPQGTKGKGEDSTLASSMGEATNSKFLQGVGFNPFQERGN 697
                  + ++ G  GT        T  +         M +     F + +GF     +G 
Sbjct: 1017 LLTDGSEKDKKGKGGTKTL---MNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGL 1073

Query: 698  NIVTYEWAKDLLTNYQTGVLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFL 757
            ++                    S K  LL  ++ +      K+L+F Q  S + ++E++ 
Sbjct: 1074 DLY-----------------RASGKFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYF 1116

Query: 758  GKREVPCPPGTEGQGAQKWVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTR 817
                                R   Y RLDG+T A +R  L+  FN+P +   ++FLLSTR
Sbjct: 1117 A------------------YRGFKYLRLDGTTKAEDRGMLLKTFNEPGS-EYFIFLLSTR 1157

Query: 818  AGCLGVNLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKI--- 874
            AG LG+NL  A+ V++FD+ WNP  D QA  R +R GQ+    + RL    ++E+KI   
Sbjct: 1158 AGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAA 1217

Query: 875  ------YDRQISKQGMSDR 887
                   D+++ + GM D+
Sbjct: 1218 AKYKLNVDQKVIQAGMFDQ 1236



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 74/285 (25%), Positives = 120/285 (42%), Gaps = 36/285 (12%)

Query: 82  SEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLEPVTKAAQQEELERRKRLE 141
           +E +R+H+   +A E  KKK+ +K  +       +  +   EP+ + +Q  +L  +    
Sbjct: 565 TELVRQHKAAQVAKEKKKKKKKKKAENAEGQTPAIGPDG--EPLDETSQMSDLPVKVIHV 622

Query: 142 QQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGSEDEKSSRDEV 201
           +  K           +    E  L  + G ++ PR  ++E       SGSE+E+   +E 
Sbjct: 623 ESGKILTGTDAPKAGQL---EAWLEMNPGYEVAPRSDSEE-------SGSEEEEEEEEEE 672

Query: 202 IELSSGEEDTLHIVDS-------SESVSEDDEEE--EKGGTHVNDVLNQRDALGRVLVNL 252
            +  + +  TL + +        S+ VSE D     E     V+D      AL R L + 
Sbjct: 673 -QPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGVSQALARGLQSY 731

Query: 253 ----NHPPEEENVFLAPQLARAVKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMG 308
               +   E  +   A  +   +K +QI G+ +L      +L           ILA  MG
Sbjct: 732 YAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNG---------ILADEMG 782

Query: 309 LGKTLQVISFIDVLFRHTPAK-TVLAIVPVNTLQNWLAEFNMWLP 352
           LGKT+Q I+ I  L  H       L IVP++TL NW  EF+ W P
Sbjct: 783 LGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAP 827


>gi|164419749 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a1 isoform b [Homo sapiens]
          Length = 1042

 Score =  118 bits (296), Expect = 4e-26
 Identities = 67/174 (38%), Positives = 101/174 (58%), Gaps = 19/174 (10%)

Query: 716 VLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQK 775
           ++ NS KMV+L  L+ +  + G ++L+FSQ    L ++E++                   
Sbjct: 481 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYC-----------------M 523

Query: 776 WVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFD 835
           W R   Y RLDG TP  ERE  I  FN P N + ++F+LSTRAG LG+NL  A+ V+++D
Sbjct: 524 W-RGYEYCRLDGQTPHEEREEAIEAFNAP-NSSKFIFMLSTRAGGLGINLASADVVILYD 581

Query: 836 ASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVV 889
           + WNP  D QA+ R +R GQKKP  ++RL+ D T+E++I +R   K  +   V+
Sbjct: 582 SDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVI 635



 Score =  108 bits (270), Expect = 4e-23
 Identities = 103/364 (28%), Positives = 166/364 (45%), Gaps = 92/364 (25%)

Query: 271 VKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVL--FRHTPA 328
           ++ +QI G+ +L  +L E+        G   ILA  MGLGKTLQ I+ +  L  +R+ P 
Sbjct: 183 LRDYQIRGLNWLI-SLYEN--------GVNGILADEMGLGKTLQTIALLGYLKHYRNIPG 233

Query: 329 KTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAK 388
             ++ +VP +TL NW+ EF  W+                P    +  + D+     +RA 
Sbjct: 234 PHMV-LVPKSTLHNWMNEFKRWV----------------PSLRVICFVGDKD----ARAA 272

Query: 389 VMADWVSEG--GVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRR 446
            + D +  G   V +  YEM                            + E+   ++F  
Sbjct: 273 FIRDEMMPGEWDVCVTSYEMV---------------------------IKEKSVFKKFHW 305

Query: 447 EFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMV 506
            +           ++ DE HRIKN ++  S+ ++  +S  R++LTG PLQNNL E W ++
Sbjct: 306 RY-----------LVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALL 354

Query: 507 DFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTV 566
           +F+ PD   +  +F + F+     G        D +L+      LH++L+ F+ RR  T 
Sbjct: 355 NFLLPDVFNSADDFDSWFDTKNCLG--------DQKLVER----LHAVLKPFLLRRIKTD 402

Query: 567 LKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRD-CGSSGWLG----LNPLKAFCVCCKI 621
           ++  LP K+E  I + LSK+QR+ YT+ + +  D   SSG +     LN L     CC  
Sbjct: 403 VEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCC-- 460

Query: 622 WNHP 625
            NHP
Sbjct: 461 -NHP 463


>gi|21071058 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a5 [Homo sapiens]
          Length = 1052

 Score =  114 bits (285), Expect = 7e-25
 Identities = 65/174 (37%), Positives = 101/174 (58%), Gaps = 19/174 (10%)

Query: 716 VLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQK 775
           ++ NS KMV+L  L+ +  + G ++L+FSQ    L ++E++                   
Sbjct: 478 LVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDILEDYC-----------------M 520

Query: 776 WVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFD 835
           W RN  Y RLDG TP  ER+  IN +N+P N T ++F+LSTRAG LG+NL  A+ V+++D
Sbjct: 521 W-RNYEYCRLDGQTPHDERQDSINAYNEP-NSTKFVFMLSTRAGGLGINLATADVVILYD 578

Query: 836 ASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVV 889
           + WNP  D QA+ R +R GQ K   ++R + D T+E++I +R   K  +   V+
Sbjct: 579 SDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVI 632



 Score =  110 bits (275), Expect = 1e-23
 Identities = 99/336 (29%), Positives = 153/336 (45%), Gaps = 79/336 (23%)

Query: 297 SGFGCILAHSMGLGKTLQVISFIDVL--FRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPP 354
           +G   ILA  MGLGKTLQ IS +  +  +R+ P   ++ +VP +TL NW++EF  W+P  
Sbjct: 197 NGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMV-LVPKSTLHNWMSEFKRWVPTL 255

Query: 355 EALPADNKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKK 414
            +                V ++ D+ +  A    V+     E  V +  YEM  L+  K 
Sbjct: 256 RS----------------VCLIGDKEQRAAFVRDVLLP--GEWDVCVTSYEM--LIKEKS 295

Query: 415 SFATGRPKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQAS 474
            F     KK   R                                ++ DE HRIKN ++ 
Sbjct: 296 VF-----KKFNWR-------------------------------YLVIDEAHRIKNEKSK 319

Query: 475 TSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCI 534
            S+ ++  ++  R++LTG PLQNNL E W +++F+ PD   +  +F + F+       C+
Sbjct: 320 LSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSWFD----TNNCL 375

Query: 535 DSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQF 594
                D +L+      LH +L  F+ RR    ++  LP K+E  I V LSK+QR+ YT+ 
Sbjct: 376 G----DQKLVER----LHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRI 427

Query: 595 MDRFRD-CGSSGWLG----LNPLKAFCVCCKIWNHP 625
           + +  D   S+G +     LN L     CC   NHP
Sbjct: 428 LMKDIDILNSAGKMDKMRLLNILMQLRKCC---NHP 460


>gi|21071044 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a1 isoform a [Homo sapiens]
          Length = 1054

 Score =  109 bits (273), Expect = 2e-23
 Identities = 67/186 (36%), Positives = 101/186 (54%), Gaps = 31/186 (16%)

Query: 716 VLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQK 775
           ++ NS KMV+L  L+ +  + G ++L+FSQ    L ++E++                   
Sbjct: 481 IVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDILEDYC-----------------M 523

Query: 776 WVRNISYFRLDGSTPAFERE------------RLINQFNDPSNLTTWLFLLSTRAGCLGV 823
           W R   Y RLDG TP  ERE              I  FN P N + ++F+LSTRAG LG+
Sbjct: 524 W-RGYEYCRLDGQTPHEEREDKFLEVEFLGQREAIEAFNAP-NSSKFIFMLSTRAGGLGI 581

Query: 824 NLIGANRVVVFDASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQG 883
           NL  A+ V+++D+ WNP  D QA+ R +R GQKKP  ++RL+ D T+E++I +R   K  
Sbjct: 582 NLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLR 641

Query: 884 MSDRVV 889
           +   V+
Sbjct: 642 LDSIVI 647



 Score =  108 bits (270), Expect = 4e-23
 Identities = 103/364 (28%), Positives = 166/364 (45%), Gaps = 92/364 (25%)

Query: 271 VKPHQIGGIRFLYDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVL--FRHTPA 328
           ++ +QI G+ +L  +L E+        G   ILA  MGLGKTLQ I+ +  L  +R+ P 
Sbjct: 183 LRDYQIRGLNWLI-SLYEN--------GVNGILADEMGLGKTLQTIALLGYLKHYRNIPG 233

Query: 329 KTVLAIVPVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAK 388
             ++ +VP +TL NW+ EF  W+                P    +  + D+     +RA 
Sbjct: 234 PHMV-LVPKSTLHNWMNEFKRWV----------------PSLRVICFVGDKD----ARAA 272

Query: 389 VMADWVSEG--GVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQQEFRR 446
            + D +  G   V +  YEM                            + E+   ++F  
Sbjct: 273 FIRDEMMPGEWDVCVTSYEMV---------------------------IKEKSVFKKFHW 305

Query: 447 EFEKALCRPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMV 506
            +           ++ DE HRIKN ++  S+ ++  +S  R++LTG PLQNNL E W ++
Sbjct: 306 RY-----------LVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALL 354

Query: 507 DFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTV 566
           +F+ PD   +  +F + F+     G        D +L+      LH++L+ F+ RR  T 
Sbjct: 355 NFLLPDVFNSADDFDSWFDTKNCLG--------DQKLVER----LHAVLKPFLLRRIKTD 402

Query: 567 LKIHLPAKEENVILVRLSKIQRDLYTQFMDRFRD-CGSSGWLG----LNPLKAFCVCCKI 621
           ++  LP K+E  I + LSK+QR+ YT+ + +  D   SSG +     LN L     CC  
Sbjct: 403 VEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCC-- 460

Query: 622 WNHP 625
            NHP
Sbjct: 461 -NHP 463


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score =  107 bits (266), Expect = 1e-22
 Identities = 176/716 (24%), Positives = 271/716 (37%), Gaps = 164/716 (22%)

Query: 1   MSDESASGSDP-------DLDPDVELEDAEEEEEEEEVAVEECDRDDEED---------- 43
           +   SA+ S P       D D D + ++ EEE++EE + VEE    ++ +          
Sbjct: 266 LGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLR 325

Query: 44  -----------------LLDDPSLEGMCGTEHAQLGEDG------QQPPRCTSTTSSQSE 80
                            LL+ PS      + H     DG      ++PP+       +  
Sbjct: 326 REGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEI---KPP 382

Query: 81  PSEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLREDQLE-------PVTKAAQQEE 133
           PS   +R++      ED ++  A +          +  E+QLE        +++ A++ E
Sbjct: 383 PSAVTQRNKQPWHPDEDDEEFTANE-EEAEDEEDTIAAEEQLEGEVDHAMELSELAREGE 441

Query: 134 LERRKRLEQQRKDYAAPIPTVPLEFLPEEIALRASDGPQLPPRVLAQEVICLDSSSGS-- 191
           L   + L+Q    YA    +   E   E  A  +   P+ P  V A+E    DSSS S  
Sbjct: 442 LSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGP--VEAEEPPQEDSSSQSDS 499

Query: 192 --------EDEKSSRDEVIELSSGEEDTLHIVDSSESVSEDDEEEEKGGTHVNDVLNQRD 243
                   EDE S  +E    S+ EE      + ++S S+ DEEEE     V  +L + +
Sbjct: 500 VEDRSEDEEDEHSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARDE 559

Query: 244 ALGRVLVNLNHPPEEENVFLAPQ-----LARAVKPHQIGGIRFL---------------- 282
                    + PP      L P+     +A A +  Q  G                    
Sbjct: 560 EQSEADAG-SGPPTPGPTTLGPKKEITDIAAAAESLQPKGYTLATTQVKTPIPLLLRGQL 618

Query: 283 -------YDNLVESLERFKTSSGFGCILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIV 335
                   D LV   E  K  +G   ILA  MGLGKT+Q IS                  
Sbjct: 619 REYQHIGLDWLVTMYE--KKLNG---ILADEMGLGKTIQTISL----------------- 656

Query: 336 PVNTLQNWLAEFNMWLPPPEALPADNKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVS 395
               L +   E   W P    +P                              VM +W  
Sbjct: 657 ----LAHLACEKGNWGPHLIIVPTS----------------------------VMLNWEM 684

Query: 396 EGGVLLMGYEMYRLLTLKKSFATGRPKKTKKRSHPVIIDLDEEDRQ--QEFRREFEKALC 453
           E       +++      +K     R   TK  +  V I   +   Q  Q FRR+  + L 
Sbjct: 685 ELKRWCPSFKILTYYGAQKERKLKRQGWTKPNAFHVCITSYKLVLQDHQAFRRKNWRYL- 743

Query: 454 RPGPDVVICDEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDF 513
                  I DE   IKN ++   Q+L N  S+RR++LTG PLQN+L+E W ++ F+ P  
Sbjct: 744 -------ILDEAQNIKNFKSQRWQSLLNFNSQRRLLLTGTPLQNSLMELWSLMHFLMPHV 796

Query: 514 LGTRQEFSNMFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPA 573
             + +EF   F  P L G    S   +  L++     LH +L  F+ RR    ++  +P 
Sbjct: 797 FQSHREFKEWFSNP-LTGMIEGSQEYNEGLVKR----LHKVLRPFLLRRVKVDVEKQMPK 851

Query: 574 KEENVILVRLSKIQRDLYTQFMDR--FRDCGSSGWLGLNPLKAFCVCCKIWNHPDV 627
           K E+VI  RLSK QR LY  FM +   ++  ++G   ++ +       K+ NHP++
Sbjct: 852 KYEHVIRCRLSKRQRCLYDDFMAQTTTKETLATGHF-MSVINILMQLRKVCNHPNL 906



 Score =  102 bits (253), Expect = 4e-21
 Identities = 73/254 (28%), Positives = 122/254 (48%), Gaps = 31/254 (12%)

Query: 722  KMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQKWVRNIS 781
            K+  L  L+ +    G ++L+F+Q    L ++E+FL                        
Sbjct: 2044 KLQTLAVLLRQLKAEGHRVLIFTQMTRMLDVLEQFLT------------------YHGHL 2085

Query: 782  YFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFDASWNPC 841
            Y RLDGST   +R+ L+ +FN    +  + F+LSTR+G +GVNL GA+ VV +D+ WNP 
Sbjct: 2086 YLRLDGSTRVEQRQALMERFNADKRI--FCFILSTRSGGVGVNLTGADTVVFYDSDWNPT 2143

Query: 842  HDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLN-PMLNFTR 900
             DAQA  R +R GQ +  +IYRL+++ T+E+ I  +   K+ + D  ++  N     F +
Sbjct: 2144 MDAQAQDRCHRIGQTRDVHIYRLISERTVEENILKKANQKRMLGDMAIEGGNFTTAYFKQ 2203

Query: 901  KEVENLLHFVEKEPAPQVSLNVKGIKESVLQLACLKYPHLITKEPFEHESLLLNRKDHKL 960
            + +  L     +EP+   S +V    E   +    K  H++       E  L   +D + 
Sbjct: 2204 QTIRELFDMPLEEPS---SSSVPSAPEEEEETVASKQTHIL-------EQALCRAEDEED 2253

Query: 961  TKAEKKAAKKSYEE 974
             +A  +A  +   E
Sbjct: 2254 IRAATQAKAEQVAE 2267


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
            sapiens]
          Length = 2997

 Score =  105 bits (263), Expect = 2e-22
 Identities = 62/199 (31%), Positives = 109/199 (54%), Gaps = 26/199 (13%)

Query: 716  VLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQK 775
            +++ + K+VL+  L+ +    G ++L+FSQ +  L ++E++L +R  P            
Sbjct: 1285 MIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYP------------ 1332

Query: 776  WVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFD 835
                  Y R+DG      R+  I++F+ P +   ++FLL TRAG LG+NL  A+  ++FD
Sbjct: 1333 ------YERIDGRVRGNLRQAAIDRFSKPDS-DRFVFLLCTRAGGLGINLTAADTCIIFD 1385

Query: 836  ASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDL--- 892
            + WNP +D QA  R +R GQ K   IYRL+   + E++++D+   K G+   V+  +   
Sbjct: 1386 SDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGR 1445

Query: 893  ----NPMLNFTRKEVENLL 907
                N +   ++KE+E+LL
Sbjct: 1446 ENATNGVQQLSKKEIEDLL 1464



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 84/340 (24%), Positives = 134/340 (39%), Gaps = 70/340 (20%)

Query: 301  CILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPAD 360
            CILA  MGLGKT+Q I+F+  ++        L I P++T+ NW  EF  W          
Sbjct: 989  CILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTW---------- 1038

Query: 361  NKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGR 420
                  +      H      +T+        D   +G V+   Y+ + ++T  +   T  
Sbjct: 1039 -----TELNVVVYHGSQASRRTIQLYEMYFKD--PQGRVIKGSYKFHAIITTFEMILTDC 1091

Query: 421  PKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALK 480
            P                E R   +R              V+ DE HR+KN      + LK
Sbjct: 1092 P----------------ELRNIPWR-------------CVVIDEAHRLKNRNCKLLEGLK 1122

Query: 481  NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQD 540
             +    +V+LTG PLQN + E + ++ F+ P    +   F   F      G     T + 
Sbjct: 1123 MMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEF------GDL--KTEEQ 1174

Query: 541  VRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDR-FR 599
            V+        L ++L+  + RR    ++ +L  KEE +I V L+ IQ+  Y   +++ F 
Sbjct: 1175 VQ-------KLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFT 1227

Query: 600  DCGSSGWLG-----LNPLKAFCVCCKIWNHPDVLYEALQK 634
                 G        LN +     CC   NHP ++  A +K
Sbjct: 1228 FLSKGGGQANVPNLLNTMMELRKCC---NHPYLINGAEEK 1264


>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
           sapiens]
          Length = 2715

 Score =  105 bits (262), Expect = 3e-22
 Identities = 62/198 (31%), Positives = 109/198 (55%), Gaps = 25/198 (12%)

Query: 716 VLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQK 775
           +++ + K+VL+  L+ + +  G K+L+FSQ +  L ++E++L +R               
Sbjct: 778 MIQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDILEDYLIQRRY------------- 824

Query: 776 WVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFD 835
                +Y R+DG      R+  I++F  P +   ++FLL TRAG LG+NL  A+  ++FD
Sbjct: 825 -----TYERIDGRVRGNLRQAAIDRFCKPDS-DRFVFLLCTRAGGLGINLTAADTCIIFD 878

Query: 836 ASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDL--- 892
           + WNP +D QA  R +R GQ K   +YRL+   + E++++D+   K G+   V+ D+   
Sbjct: 879 SDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRK 938

Query: 893 ---NPMLNFTRKEVENLL 907
              N +   ++ EVE+LL
Sbjct: 939 GGTNGVQQLSKMEVEDLL 956



 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 81/337 (24%), Positives = 134/337 (39%), Gaps = 64/337 (18%)

Query: 301 CILAHSMGLGKTLQVISFIDVLFRHTPAKTVLAIVPVNTLQNWLAEFNMWLPPPEALPAD 360
           CILA  MGLGKT+Q I+F+  +F        L I P++T+ NW  EF  W          
Sbjct: 482 CILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTW---------- 531

Query: 361 NKPEEVQPRFFKVHILNDEHKTMASRAKVMADWVSEGGVLLMGYEMYRLLTLKKSFATGR 420
                 +      H      + +     V  D  ++G  L   ++ + ++T  +      
Sbjct: 532 -----TEMNAIVYHGSQISRQMIQQYEMVYRD--AQGNPLSGVFKFHVVITTFEMILADC 584

Query: 421 PKKTKKRSHPVIIDLDEEDRQQEFRREFEKALCRPGPDVVICDEGHRIKNCQASTSQALK 480
           P+  K     VII                             DE HR+KN      + LK
Sbjct: 585 PELKKIHWSCVII-----------------------------DEAHRLKNRNCKLLEGLK 615

Query: 481 NIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSNMFERPILNGQCIDSTPQD 540
            +    +V+LTG PLQN++ E + +++F+ P    +   F   F      G     T + 
Sbjct: 616 LMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEF------GDL--KTEEQ 667

Query: 541 VRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVRLSKIQRDLYTQFMDR--- 597
           V+        L S+L+  + RR    ++ +L  K+E +I V L+ IQ+  Y   +++   
Sbjct: 668 VK-------KLQSILKPMMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFS 720

Query: 598 FRDCGSSGWLGLNPLKAFCVCCKIWNHPDVLYEALQK 634
           F   G++     N +       K  NHP ++  A +K
Sbjct: 721 FLTKGANQHNMPNLINTMMELRKCCNHPYLINGAEEK 757


>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
           [Homo sapiens]
          Length = 1828

 Score =  104 bits (259), Expect = 7e-22
 Identities = 62/178 (34%), Positives = 99/178 (55%), Gaps = 19/178 (10%)

Query: 716 VLENSPKMVLLFHLIEESVKLGDKILVFSQSLSTLALIEEFLGKREVPCPPGTEGQGAQK 775
           ++ +S K++LL  L+    + G+++L+FSQ +  L ++ E+L  +  P            
Sbjct: 786 LIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTIKHYP------------ 833

Query: 776 WVRNISYFRLDGSTPAFERERLINQFNDPSNLTTWLFLLSTRAGCLGVNLIGANRVVVFD 835
                 + RLDGS     R++ ++ FN   +   + FLLSTRAG LG+NL  A+ VV+FD
Sbjct: 834 ------FQRLDGSIKGEIRKQALDHFNADGS-EDFCFLLSTRAGGLGINLASADTVVIFD 886

Query: 836 ASWNPCHDAQAVCRVYRYGQKKPCYIYRLVADYTLEKKIYDRQISKQGMSDRVVDDLN 893
           + WNP +D QA  R +R GQKK   IYRLV   T+E++I +R   K  +   V+  ++
Sbjct: 887 SDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMD 944



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 58/195 (29%), Positives = 93/195 (47%), Gaps = 25/195 (12%)

Query: 463 DEGHRIKNCQASTSQALKNIRSRRRVVLTGYPLQNNLIEYWCMVDFVRPDFLGTRQEFSN 522
           DE HR+KN  +   + L + +S  R+++TG PLQN+L E W ++ F+ P+    + EF  
Sbjct: 617 DEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPE----KFEFWE 672

Query: 523 MFERPILNGQCIDSTPQDVRLMRYRSHVLHSLLEGFVQRRGHTVLKIHLPAKEENVILVR 582
            FE     G          R   Y+S  LH +LE F+ RR    ++  LPAK E ++ V 
Sbjct: 673 DFEEDHGKG----------RENGYQS--LHKVLEPFLLRRVKKDVEKSLPAKVEQILRVE 720

Query: 583 LSKIQRDLYTQFMDRFRDCGSSGWLG-----LNPLKAFCVCCKIWNHPDVLYEALQKESL 637
           +S +Q+  Y   + R     + G  G     LN +     CC   NH   L +  ++   
Sbjct: 721 MSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCC---NH-CYLIKPPEENER 776

Query: 638 ANEQDLDVEELGSAG 652
            N Q++ +  + S+G
Sbjct: 777 ENGQEILLSLIRSSG 791



 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 26/52 (50%), Positives = 34/52 (65%), Gaps = 1/52 (1%)

Query: 302 ILAHSMGLGKTLQVISFIDVLF-RHTPAKTVLAIVPVNTLQNWLAEFNMWLP 352
           ILA  MGLGKT+Q ISF+  LF +H      L +VP++TL +W  EF +W P
Sbjct: 506 ILADEMGLGKTIQTISFLSYLFHQHQLYGPFLIVVPLSTLTSWQREFEIWAP 557



 Score = 34.7 bits (78), Expect = 0.69
 Identities = 48/258 (18%), Positives = 99/258 (38%), Gaps = 20/258 (7%)

Query: 4   ESASGSDPDLDPDVELEDAEEEEEEEEVAVEECDRDDEEDLLDDPSLEGMCGTEHA---- 59
           ES  GSDP      E   + E  E +  +  E      + +L +   +     E      
Sbjct: 38  ESEQGSDPGSGHGSESNSSSESSESQSESESESAGSKSQPVLPEAKEKPASKKERIADVK 97

Query: 60  QLGEDGQQPPRCTSTTSSQSEPSEQLRRHQGKNLASEDPKKKRAQKPSHMRRNIRKLLRE 119
           ++ E+         +  S+ EPS    + +  + +     K+R Q+    +   ++   E
Sbjct: 98  KMWEEYPDVYGVRRSNRSRQEPSRFNIKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSE 157

Query: 120 DQLEPVTKAAQQEELERRKRLEQQRKDYAAPIPTVPLEFLP---------EEIALRASDG 170
           D+ E  T A  + E   +K+++ +R      +P   ++  P         ++ +    D 
Sbjct: 158 DEQEQGTSAESEPE---QKKVKARRPVPRRTVPKPRVKKQPKTQRGKRKKQDSSDEDDDD 214

Query: 171 PQLPPRVLAQEVICLDSSSGSEDEKSSRDEVIELSSGEEDTLHIVDSSESVSE--DDEEE 228
            + P R   +      S    +D ++  D++IE++    D     D+SE++ +  D    
Sbjct: 215 DEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIEMTGEGVDEQQ--DNSETIEKVLDSRLG 272

Query: 229 EKGGTHVNDVLNQRDALG 246
           +KG T  +  +   +A G
Sbjct: 273 KKGATGASTTVYAIEANG 290


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,571,617
Number of Sequences: 37866
Number of extensions: 3241830
Number of successful extensions: 22537
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 180
Number of HSP's successfully gapped in prelim test: 432
Number of HSP's that attempted gapping in prelim test: 16568
Number of HSP's gapped (non-prelim): 4283
length of query: 1467
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1352
effective length of database: 13,892,928
effective search space: 18783238656
effective search space used: 18783238656
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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