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Search of human proteins with 167900474
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167900474 coiled-coil domain containing 75 [Homo sapiens]
(259 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167900474 coiled-coil domain containing 75 [Homo sapiens] 523 e-149
gi|39725952 angiogenic factor VG5Q [Homo sapiens] 53 3e-07
gi|148746195 trichohyalin [Homo sapiens] 52 7e-07
gi|50962882 G patch domain containing 8 [Homo sapiens] 50 1e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 48 7e-06
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 47 2e-05
gi|20127479 RNA binding motif protein 10 isoform 1 [Homo sapiens] 47 2e-05
gi|23111018 RNA binding motif protein 10 isoform 2 [Homo sapiens] 47 2e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 6e-05
gi|56788356 tuftelin interacting protein 11 [Homo sapiens] 45 6e-05
gi|8393259 tuftelin interacting protein 11 [Homo sapiens] 45 6e-05
gi|33469964 splicing factor 4 [Homo sapiens] 45 6e-05
gi|224282119 splicing factor, arginine/serine-rich 14 [Homo sapi... 45 8e-05
gi|224282117 splicing factor, arginine/serine-rich 14 [Homo sapi... 45 8e-05
gi|63003897 transcription factor NRF [Homo sapiens] 44 2e-04
gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo s... 44 2e-04
gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo s... 44 2e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 43 3e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 42 4e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 42 5e-04
gi|110815815 centlein isoform 1 [Homo sapiens] 42 7e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 41 0.001
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 41 0.001
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 41 0.001
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 41 0.001
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 41 0.001
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 41 0.001
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 41 0.001
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 41 0.001
gi|4502395 beclin 1 [Homo sapiens] 41 0.001
>gi|167900474 coiled-coil domain containing 75 [Homo sapiens]
Length = 259
Score = 523 bits (1347), Expect = e-149
Identities = 259/259 (100%), Positives = 259/259 (100%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD
Sbjct: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA
Sbjct: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQV 180
EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQV
Sbjct: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQV 180
Query: 181 PREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAY 240
PREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAY
Sbjct: 181 PREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAY 240
Query: 241 EDKEDLSSNCPGPTSADHD 259
EDKEDLSSNCPGPTSADHD
Sbjct: 241 EDKEDLSSNCPGPTSADHD 259
>gi|39725952 angiogenic factor VG5Q [Homo sapiens]
Length = 714
Score = 52.8 bits (125), Expect = 3e-07
Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 4/138 (2%)
Query: 19 IRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDI--GLKNALGCENKGFAL 76
++ GL E K K ++ K R++ E +R D + + + NKG +
Sbjct: 567 VKYGLQNTEYEDEKTLKNPKYKDRAGKRREQVGSEGTFQRDDAPASVHSEITDSNKGRKM 626
Query: 77 LQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQ 136
L+KMG+K G+ LGK GGG+ PI L ++ +G+G + L++ KK ++
Sbjct: 627 LEKMGWKKGEGLGKDGGGMKTPIQLQLRRTHAGLGTGKPSSFEDVHLLQNKNKK--NWDK 684
Query: 137 AEEKAAEQFRMRLKNKQD 154
A E+ E F K D
Sbjct: 685 ARERFTENFPETKPQKDD 702
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 51.6 bits (122), Expect = 7e-07
Identities = 50/213 (23%), Positives = 105/213 (49%), Gaps = 15/213 (7%)
Query: 27 RQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQ 86
R+ +E RR+++ ++E + Q+ +E+E+ERR+ L+ E + L ++ + Q
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 87 ALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFR 146
L + E + + E L+R+ + + E ++ + + E+K ++ R
Sbjct: 388 QLRREQQLRRE----QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR 443
Query: 147 -MRLKNKQDE----MKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETE-EDEEE 200
RLK +Q+E +K E + R ++ ++ ++++ + R WL+LEEE E +E
Sbjct: 444 EQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE-RWLKLEEEERREQQER 502
Query: 201 KEQ----DEDEYKSEDLSVLEKLQILTSYLREE 229
+EQ +++E + + L E+ + L LR E
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSE 535
Score = 51.6 bits (122), Expect = 7e-07
Identities = 53/222 (23%), Positives = 105/222 (47%), Gaps = 41/222 (18%)
Query: 27 RQIREARRK-----EEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMG 81
R E RR+ EE+++ + R++ L+ E++ERR+ LK + + L Q++
Sbjct: 478 RDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR----QEEEERLQQRL- 532
Query: 82 YKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKA 141
+S Q L + + E LKR+ E++LE R++ +K + EE+
Sbjct: 533 -RSEQQLRR----------------EQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 142 -------AEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREA------WYWL 188
E+ + RLK +Q+E +LE L+R + + + ++ ++ RE L
Sbjct: 576 DQLLKREEERRQQRLKREQEE-RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634
Query: 189 RLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEH 230
+ EE+ E +++ +++ E + + L E+ + L L+ EH
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH 676
Score = 50.4 bits (119), Expect = 1e-06
Identities = 47/211 (22%), Positives = 96/211 (45%), Gaps = 20/211 (9%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
+ EEE +E +R + RQ R+EE+QQ+ L+ Q+ +++E+ERR+
Sbjct: 260 LQEEEPQRQRELQEEEEQLRK---LERQELRRERQEEEQQQQRLRREQQLRRKQEEERRE 316
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
+ E + ++ + Q L + E ++ + E L+R+
Sbjct: 317 QQEERREQQERR-----EQQEERREQQLRREQ---EERREQQLRREQEEERREQQLRREQ 368
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQV 180
EE+ R++ ++ + + + +Q R ++ +++ E LRR Q+ ++ +++ Q+
Sbjct: 369 EEE----RREQQLRREQQLRREQQLR-----REQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 181 PREAWYWLRLEEETEEDEEEKEQDEDEYKSE 211
RE EEE E + E+E+ E K E
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKRE 450
Score = 49.3 bits (116), Expect = 3e-06
Identities = 53/207 (25%), Positives = 95/207 (45%), Gaps = 24/207 (11%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
+ E++ + + QE+ LR ++ RR++E+++E LK ++ K EQERR+
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEE--KRLEQERRE 564
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
LK E + LL++ + Q L + + E LKR+
Sbjct: 565 QRLKREQ--EERRDQLLKREEERRQQRLKREQEERL----------------EQRLKREE 606
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQV 180
E+LE ++ + + EE E+ + LK+++ E + + LRR Q Q+ Q+ +
Sbjct: 607 VERLEQEERR-EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ---QERREQRLKRE 662
Query: 181 PREAWYWLRLEEETEEDEEEKEQDEDE 207
E RL+ E EE+ E+E E+E
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEE 689
Score = 45.1 bits (105), Expect = 6e-05
Identities = 51/233 (21%), Positives = 93/233 (39%), Gaps = 47/233 (20%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
+ +E+ + + +Q + R Q R+ R +E+ QQE R++ K QER
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQER-- 956
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
+ + +K+ K Q LG E KR+
Sbjct: 957 ----------ERQYRKDKKLQQKEEQLLG-----------------------EEPEKRRR 983
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQV 180
+E+ + YR EE+ +Q +L ++ E + + R R +L Q+ Q+
Sbjct: 984 QEREKKYR---------EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQ-QEEEQL 1033
Query: 181 PREAWYWLRLEEETEE--DEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHL 231
RE RL+E + +EEE +Q+E++ E+ + ++ Y +EE L
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEEL 1086
Score = 44.7 bits (104), Expect = 8e-05
Identities = 44/206 (21%), Positives = 93/206 (45%), Gaps = 12/206 (5%)
Query: 27 RQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQ 86
+Q R +R +++ E + RQ+ + EE+ + L++ G E + F +++ +
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
Query: 87 ALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFR 146
L + G + K E + EE+ + +RK+ + + EEK E+
Sbjct: 217 ELRRKG-----------REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 147 MRLKNKQDEMKLEGDLRRSQ-RACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDE 205
R + Q+E + L R + R +Q + Q+ ++ RE + EEE E +EE+ + +
Sbjct: 266 QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 206 DEYKSEDLSVLEKLQILTSYLREEHL 231
+ + ++ ++L+ RE+ L
Sbjct: 326 ERREQQEERREQQLRREQEERREQQL 351
Score = 44.7 bits (104), Expect = 8e-05
Identities = 56/226 (24%), Positives = 103/226 (45%), Gaps = 34/226 (15%)
Query: 4 EEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGL 63
EE+ + ++ +R R+ R R++EE++ + L++ Q+ +E+E ERR+ L
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE-ERREQLL 550
Query: 64 K----NALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRK 119
K L E + L ++ + Q L + + LKR+
Sbjct: 551 KREEEKRLEQERREQRLKREQEERRDQLLKREEE-----------------RRQQRLKRE 593
Query: 120 AEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRS--QRACQQLDVQKN 177
EE+LE K+ ++ +E+ EQ RLK ++ E + L +S Q +Q +++
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQ---RLKREEPEEERRQQLLKSEEQEERRQQQLRRE 650
Query: 178 IQVPREAWYWLRLEEETEEDEEE---KEQDEDEYKSEDLSVLEKLQ 220
Q RE RL+ E EE+ E K + E+E + ++L+ E+ Q
Sbjct: 651 QQERREQ----RLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/215 (21%), Positives = 103/215 (47%), Gaps = 25/215 (11%)
Query: 27 RQIREARRKEEKQQEANLKNRQKSLKEEEQERRD-----IGLKNALGCENKGFALLQKMG 81
RQ R+ + +EE+QQ + +K L+EE+Q RR + L E + L ++
Sbjct: 1686 RQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER 1745
Query: 82 YKSGQALGKSGGGIVEPIPLNIKTGKSGI-GHEASLKRKAEEKLESYRKKIHMKNQ-AEE 139
Y+ I+E L + + + E K + EE+L R++ +++Q ++
Sbjct: 1746 YRK----------ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDR 1795
Query: 140 KAAEQFRMRLKNKQDEMK---LEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEE 196
K E+ ++R + ++ +++ +G R + Q + ++ ++ R+ Y R EE+
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY--RAEEQFAT 1853
Query: 197 DEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHL 231
E+ + ++++ ++ E+ ++ Q LREEH+
Sbjct: 1854 QEKSRREEQELWQEEE---QKRRQERERKLREEHI 1885
Score = 43.5 bits (101), Expect = 2e-04
Identities = 50/226 (22%), Positives = 98/226 (43%), Gaps = 16/226 (7%)
Query: 16 QEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFA 75
QE+ R ++ RE R K E+++ + R++ + EQERR LK E +
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 76 L------LQKMGYKSGQALGKSGGGIVEPIPLNIKTG------KSGIGHEASLKRKAEEK 123
L ++ + Q L + E +K + + E L+R+ EE+
Sbjct: 489 LKLEEEERREQQERREQQLRREQ---EERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545
Query: 124 LESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPRE 183
E K+ K +E+ ++ + + ++D++ + RR QR ++ + + ++ RE
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605
Query: 184 AWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREE 229
L +EE E ++E+ E+E + + L E+ + LR E
Sbjct: 606 EVERLE-QEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE 650
Score = 43.1 bits (100), Expect = 2e-04
Identities = 61/256 (23%), Positives = 105/256 (41%), Gaps = 48/256 (18%)
Query: 15 VQEDIRPGLPMLRQIREARRKEEKQ------QEANLKNRQKSLKEEEQERRDIGLKNALG 68
+QE +R +L++ E ++EE++ QE + ++ +EEEQ R+ K
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954
Query: 69 CENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASL------------ 116
+ + +K+ K Q LG+ EP + + E L
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGE------EPEKRRRQEREKKYREEEELQQEEEQLLREER 1008
Query: 117 -KRKAEEKLESYRKKIHMKNQAEEKAAE------------QFRMRLKNKQDEMKLEGDLR 163
KR+ +E YRKK ++ + E+ E Q+R + +Q+E +L G+ R
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEER 1068
Query: 164 RSQRACQQLDVQ--KNIQVPREAWYWLRLEEETEED--------EEEKEQDEDEYKSEDL 213
++R Q+L+ Q K ++ +E LR E E EEE+ Q E+E +
Sbjct: 1069 ETRRR-QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Query: 214 SVLEKLQILTSYLREE 229
+ Q L REE
Sbjct: 1128 REKRRRQELERQYREE 1143
Score = 42.4 bits (98), Expect = 4e-04
Identities = 46/228 (20%), Positives = 91/228 (39%), Gaps = 35/228 (15%)
Query: 2 AEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDI 61
AEEE S +E R++ E RRK ++++ + RQ + +EE+E+
Sbjct: 188 AEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKE-- 245
Query: 62 GLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAE 121
K +L+K K + E +R+ +
Sbjct: 246 --------WRKRETVLRKEEEKLQE-------------------------EEPQRQRELQ 272
Query: 122 EKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVP 181
E+ E RK + + E + EQ + RL+ +Q + + + RR Q+ ++ ++ Q
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 182 REAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREE 229
LR E+E +++ + + E+E + + L ++ + LR E
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRRE 380
Score = 42.0 bits (97), Expect = 5e-04
Identities = 53/248 (21%), Positives = 106/248 (42%), Gaps = 17/248 (6%)
Query: 4 EEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGL 63
E+ Y + + +E+ +LR+ RE RR++E +++ K+ + +EEEQ R+
Sbjct: 987 EKKYREEEELQQEEE-----QLLREEREKRRRQEWERQYRKKDELQ--QEEEQLLREERE 1039
Query: 64 KNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEK 123
K L + + +++ + Q LG+ E + + E L+++ E+
Sbjct: 1040 KRRLQERERQYREEEELQQEEEQLLGE------ERETRRRQELERQYRKEEELQQEEEQL 1093
Query: 124 L----ESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQ 179
L E R++ + EE+ +Q +L ++ E + +L R R +++ ++
Sbjct: 1094 LREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Query: 180 VPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTA 239
+ E R E E + EEE+ Q E+E + + + Y EE L
Sbjct: 1154 LREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Query: 240 YEDKEDLS 247
Y D++ S
Sbjct: 1214 YRDEDQRS 1221
Score = 40.0 bits (92), Expect = 0.002
Identities = 46/193 (23%), Positives = 85/193 (44%), Gaps = 39/193 (20%)
Query: 26 LRQIREARRKEEKQQEANLKNRQKSLKEE---EQERRDIGLKNALGCENKGFALLQKMGY 82
LR+ ++ RR+++ ++E L+ Q+ + E EQERR+ LK E + + ++
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE-ERRDWLKREEETE 465
Query: 83 KSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEE-------KLESYRKKIHMKN 135
+ Q K LKR EE KLE ++ +
Sbjct: 466 RHEQERRKQ-----------------------QLKRDQEEERRERWLKLEEEERREQQER 502
Query: 136 QAEEKAAEQ---FRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEE 192
+ ++ EQ RLK +++E +L+ LR Q+ ++ + ++ + RE RLE+
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE--EKRLEQ 560
Query: 193 ETEEDEEEKEQDE 205
E E ++EQ+E
Sbjct: 561 ERREQRLKREQEE 573
Score = 38.5 bits (88), Expect = 0.006
Identities = 43/214 (20%), Positives = 98/214 (45%), Gaps = 15/214 (7%)
Query: 30 REARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALG 89
+E RR+++ ++E + Q+ +EEE+ER + LK E + L ++ ++ + +
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK 698
Query: 90 KSGGGIVEPIPLNIKTGKSGI----GHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQF 145
+ +S + + +R+ E++ + R++ ++ Q EE+A Q
Sbjct: 699 SRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ 758
Query: 146 RMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEE--------TEED 197
+ + + + + + +S+R Q+L + ++ RE LR EE EE+
Sbjct: 759 QEEEQRRDFTWQWQAE-EKSERGRQRLSARPPLREQRER--QLRAEERQQREQRFLPEEE 815
Query: 198 EEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHL 231
E+E+ + + + ++L LE+ + L R + L
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQL 849
Score = 38.5 bits (88), Expect = 0.006
Identities = 22/96 (22%), Positives = 51/96 (53%), Gaps = 2/96 (2%)
Query: 119 KAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNI 178
+AEEK E R+++ + E+ Q R + ++++ L + + QR Q+ + +K +
Sbjct: 772 QAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL 831
Query: 179 QVPREAWYWLRLE--EETEEDEEEKEQDEDEYKSED 212
Q E R E ++ +E+E+ ++D++ +S++
Sbjct: 832 QFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867
Score = 37.7 bits (86), Expect = 0.010
Identities = 58/257 (22%), Positives = 107/257 (41%), Gaps = 58/257 (22%)
Query: 2 AEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKE----EKQQEANLKNRQKSLKEEE-- 55
AEE F+ +E+ R+ R R KE E++++ + R + L+EEE
Sbjct: 800 AEERQQREQRFLPEEEEKE----QRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
Query: 56 -----------QERRDIGLKNALGCENK-------GFALLQKMGYKSGQALGKSGGGIVE 97
++RRD + L E K LQ+ K Q L +
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE------ 909
Query: 98 PIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMK 157
+ + E KR+ +E+ YR++ ++ Q EE+ + R + + ++ E +
Sbjct: 910 ---------EEELQREEREKRRRQEQERQYREEEQLQ-QEEEQLLREEREKRRRQERERQ 959
Query: 158 LEGDLRRSQRACQQL--DVQKNIQVPREAWYWLRLEEETEEDEEE----------KEQDE 205
D + Q+ Q L + +K + RE Y R EEE +++EE+ +++ E
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKY--REEEELQQEEEQLLREEREKRRRQEWE 1017
Query: 206 DEYKSEDLSVLEKLQIL 222
+Y+ +D E+ Q+L
Sbjct: 1018 RQYRKKDELQQEEEQLL 1034
Score = 35.8 bits (81), Expect = 0.038
Identities = 42/200 (21%), Positives = 90/200 (45%), Gaps = 9/200 (4%)
Query: 27 RQIREARRKEEKQQ----EANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGY 82
RQ R+ + EE+QQ E + K R++ L+ +E ER+ + + L + + LQ+
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539
Query: 83 KSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAA 142
Q G+ + + + + +++ + K +K+ + Q +
Sbjct: 1540 LRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME 1599
Query: 143 EQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKE 202
++ ++R + Q +++ E D R+ + Q L ++ Q+ R+ LEEE + +E+E
Sbjct: 1600 DEQQLRRQEGQQQLRQERD-RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQERE 1658
Query: 203 Q----DEDEYKSEDLSVLEK 218
Q D D E+ +L++
Sbjct: 1659 QQLRHDRDRKFREEEQLLQE 1678
Score = 35.8 bits (81), Expect = 0.038
Identities = 40/216 (18%), Positives = 95/216 (43%), Gaps = 11/216 (5%)
Query: 16 QEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFA 75
Q+ R L +Q+R R ++++Q+ + K R++ +E+E + + + ++ F
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE----RDRKFR 1582
Query: 76 LLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKN 135
L ++ + Q + + L + G+ + E K + +E+L R++ +
Sbjct: 1583 LEEQKVRRQEQ----ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR 1638
Query: 136 QAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETE 195
Q ++ + +L+ ++ E +L D R R +QL + Q R R + E
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ---ERDRKFRE 1695
Query: 196 EDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHL 231
E+++ + Q+ + ++ L + ++ + EE L
Sbjct: 1696 EEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731
Score = 33.5 bits (75), Expect = 0.19
Identities = 44/232 (18%), Positives = 90/232 (38%), Gaps = 63/232 (27%)
Query: 31 EARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGK 90
E RR+ E + + + R ++EE++RRD + QA K
Sbjct: 737 EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQ--------------------WQAEEK 776
Query: 91 SGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESY-RKKIHMKNQAEEKAAEQFRMRL 149
S + G+ + L+ + E +L + R++ + EE+ EQ R +
Sbjct: 777 S------------ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQR 824
Query: 150 KNKQDEMKL---EGDLRRSQRACQQLDVQKNIQVPREA-----------WYWL------- 188
+ ++ E++ E L+R +RA Q + + +Q +E W W
Sbjct: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKR 884
Query: 189 ---------RLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHL 231
L+E+ ++++ +++E+E + E+ + + Y EE L
Sbjct: 885 RRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Score = 32.7 bits (73), Expect = 0.32
Identities = 44/198 (22%), Positives = 91/198 (45%), Gaps = 15/198 (7%)
Query: 26 LRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSG 85
LRQ R+ + +EE+QQ + + +K +EE+Q RR + L E + + +
Sbjct: 1408 LRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467
Query: 86 QALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQF 145
Q L + E + + + E L+R +E+ +R++ +++Q E+ +
Sbjct: 1468 QLLQER----EEQQLHRQERDRKFLEEEQQLRR--QERDRKFREQ-ELRSQEPERKFLEE 1520
Query: 146 RMRLKNKQDEMKL---EGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKE 202
+L +Q + K E LRR +R QQ ++ + E +L +E EE + ++
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERG-QQRRQDRDRKFREEE----QLRQEREEQQLSRQ 1575
Query: 203 QDEDEYKSEDLSVLEKLQ 220
+ + +++ E+ V + Q
Sbjct: 1576 ERDRKFRLEEQKVRRQEQ 1593
Score = 32.7 bits (73), Expect = 0.32
Identities = 41/190 (21%), Positives = 83/190 (43%), Gaps = 13/190 (6%)
Query: 27 RQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFA----LLQKMGY 82
RQ R+ + + E+Q+ + +K +++E+Q RR G + ++ F LLQ+
Sbjct: 1574 RQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE 1633
Query: 83 KSGQALGKSGGGIVEPIPLNIKTGKSGIGH--------EASLKRKAEEKLESYRKKIHMK 134
+ + + E L + + + H E L ++ EE+ +++
Sbjct: 1634 QQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKF 1693
Query: 135 NQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQ-KNIQVPREAWYWLRLEEE 193
+ E++ Q R R ++++ +L R R +QL + + Q+ R+ Y LEEE
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753
Query: 194 TEEDEEEKEQ 203
E E++Q
Sbjct: 1754 QLRPEREEQQ 1763
Score = 32.3 bits (72), Expect = 0.42
Identities = 42/228 (18%), Positives = 95/228 (41%), Gaps = 45/228 (19%)
Query: 25 MLRQIREARRKEE-----KQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQK 79
+LR+ RE RR++E +++E + ++ L+EE ++RR L+
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQ------------- 1169
Query: 80 MGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAE- 138
Y+ + L + + ++ + E + + EE+L+ ++K +++ +
Sbjct: 1170 --YREEEELQQEEEQL-------LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Query: 139 -----------EKAAEQFRMRLKNKQDEM--KLEGDLRRSQRACQQLD----VQKNIQVP 181
E A ++ K +++E +LE R +++ Q L Q+
Sbjct: 1221 SDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDRE 1280
Query: 182 REAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREE 229
+E W + + E+E+ + +++ E K D E+ Q+L E+
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEK 1328
Score = 31.6 bits (70), Expect = 0.72
Identities = 43/215 (20%), Positives = 95/215 (44%), Gaps = 18/215 (8%)
Query: 24 PMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYK 83
P Q+ +KE K+++ + ++ L+EE +E+R + E + LLQ+ +
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEE--QLLQEREEQ 1351
Query: 84 SGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKR--------KAEEKLESYRKKIHMKN 135
+ + E + + + G+ + E L+R K E++L ++ ++
Sbjct: 1352 PLRRQERDRKFREEELR-HQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Query: 136 QAEEKAAEQFRMRLKNKQDEM--KLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEE 193
+ K E+ + + ++D + E +RR +R + L+ ++ ++ R + R EE+
Sbjct: 1411 DRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKF--REEEQ 1468
Query: 194 TEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLRE 228
++ EE++ E D LE+ Q L R+
Sbjct: 1469 LLQEREEQQLHRQE---RDRKFLEEEQQLRRQERD 1500
Score = 29.6 bits (65), Expect = 2.7
Identities = 44/195 (22%), Positives = 89/195 (45%), Gaps = 14/195 (7%)
Query: 29 IREARRKEEKQQEANLKNRQKS--LKEEE------QERRDIGLKNALGCENKGFALLQKM 80
+RE R ++ ++QE + K R++ L+E E QER + L + +G L++
Sbjct: 1321 LREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEE 1380
Query: 81 GYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEK 140
Q + + E L + + + + K + EE+ S +++ + E++
Sbjct: 1381 QRLRRQE--RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438
Query: 141 AAEQFRMRLKNKQDEMKLEGDLRRSQRACQQ-LDVQKNIQVPREAWYWLRLEEETEEDEE 199
Q R R K ++E +L + R R +Q L ++ Q+ R+ LEEE + +
Sbjct: 1439 VRRQERER-KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497
Query: 200 EKEQD--EDEYKSED 212
E+++ E E +S++
Sbjct: 1498 ERDRKFREQELRSQE 1512
Score = 29.3 bits (64), Expect = 3.6
Identities = 24/125 (19%), Positives = 56/125 (44%), Gaps = 8/125 (6%)
Query: 107 KSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQ 166
K + E KR+ +E +R++ + + EE+ + ++D E +LR +
Sbjct: 1318 KQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR------RQERDRKFREEELRHQE 1371
Query: 167 RACQQLDVQKNIQVPREAWYWLRLEEE--TEEDEEEKEQDEDEYKSEDLSVLEKLQILTS 224
+ + L+ ++ ++ +L+ E++ +E E++ QD D E+ L + +
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK 1431
Query: 225 YLREE 229
+ EE
Sbjct: 1432 FREEE 1436
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 50.4 bits (119), Expect = 1e-06
Identities = 40/133 (30%), Positives = 60/133 (45%), Gaps = 8/133 (6%)
Query: 46 NRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKT 105
N +E E L + +N G LLQK G+K GQ LGKS G +PIP+ +K
Sbjct: 17 NHFDQYEEGHLEIEQASLDKPIESDNIGHRLLQKHGWKLGQGLGKSLQGRTDPIPIVVKY 76
Query: 106 GKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRS 165
G+G AE+ E R+++ + E++ E+ R + K+ D+ K
Sbjct: 77 DVMGMGRMEMELDYAEDATE--RRRV---LEVEKEDTEELRQKYKDYVDKEKAIAKALED 131
Query: 166 QRA---CQQLDVQ 175
RA C+ D Q
Sbjct: 132 LRANFYCELCDKQ 144
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 48.1 bits (113), Expect = 7e-06
Identities = 45/181 (24%), Positives = 83/181 (45%), Gaps = 22/181 (12%)
Query: 27 RQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQ 86
R+ R+ R++E+++E K ++ K+EE+ER+ K ENK +K K +
Sbjct: 66 REKRKREREKERKRERGKKEKKGERKKEERERK----KRRREKENKEGEEKEKRKKKEKK 121
Query: 87 ALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEK-AAEQF 145
G+ T K G E +RK EE+ E RKK + + E K ++
Sbjct: 122 ERGR--------------TSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE 167
Query: 146 RMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDE 205
R ++ K++E K + R +R + + +K + R +E +++E +KE+ +
Sbjct: 168 RKQVGEKEEERKEKERKERKKRERNRKERKKERERKERR---ERKKERKKKEERKKERQK 224
Query: 206 D 206
D
Sbjct: 225 D 225
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/202 (23%), Positives = 91/202 (45%), Gaps = 20/202 (9%)
Query: 28 QIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQA 87
+I + RR+++ + A ++ +K +EEE+ + + C K L +K+G Q
Sbjct: 443 EIWKQRRRQQSEISAAVERARKRREEEERRMEE---QRKAACAEKLKRLDEKLGILEKQP 499
Query: 88 LGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRM 147
P + + + E L+++ E++ E R+K + Q +EK E
Sbjct: 500 ---------SPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELE---- 546
Query: 148 RLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDE 207
+ + KQ EM+ E + + +Q + +K +Q +E LE+E E+ EE+ E E
Sbjct: 547 KEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPN 606
Query: 208 YKSEDLSVLEKLQILTSYLREE 229
+ ++EK + S +EE
Sbjct: 607 LE----PMVEKQESENSCNKEE 624
Score = 30.8 bits (68), Expect = 1.2
Identities = 12/35 (34%), Positives = 24/35 (68%)
Query: 24 PMLRQIREARRKEEKQQEANLKNRQKSLKEEEQER 58
P +IRE R++E+++E L+ Q+ +E+E+E+
Sbjct: 499 PSPEEIREREREKEREREKELEKEQEQEREKEREK 533
Score = 29.6 bits (65), Expect = 2.7
Identities = 19/92 (20%), Positives = 42/92 (45%)
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQV 180
E+++ R++ + A + A + R + + +E + + +R ++L + +
Sbjct: 441 EDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPS 500
Query: 181 PREAWYWLRLEEETEEDEEEKEQDEDEYKSED 212
P E R +E E E EKEQ+++ K +
Sbjct: 501 PEEIREREREKEREREKELEKEQEQEREKERE 532
>gi|20127479 RNA binding motif protein 10 isoform 1 [Homo sapiens]
Length = 930
Score = 46.6 bits (109), Expect = 2e-05
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 64 KNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEK 123
++ LG +N G +LQ MG+K G LG+ GIV PI + SG+G S
Sbjct: 853 RDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGS--SYGVTS 910
Query: 124 LESYRKKIH 132
ESY++ +H
Sbjct: 911 TESYKETLH 919
>gi|23111018 RNA binding motif protein 10 isoform 2 [Homo sapiens]
Length = 852
Score = 46.6 bits (109), Expect = 2e-05
Identities = 25/69 (36%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 64 KNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEK 123
++ LG +N G +LQ MG+K G LG+ GIV PI + SG+G S
Sbjct: 775 RDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGS--SYGVTS 832
Query: 124 LESYRKKIH 132
ESY++ +H
Sbjct: 833 TESYKETLH 841
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 45.1 bits (105), Expect = 6e-05
Identities = 51/214 (23%), Positives = 93/214 (43%), Gaps = 12/214 (5%)
Query: 3 EEEDYMSDSFINVQE-DIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDI 61
EE+ + + + QE ++R LR+ +E R +EE+ QE K ++ K EQE +
Sbjct: 313 EEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMW 372
Query: 62 GLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAE 121
+ L + K ++ + + + + E + K E K + E
Sbjct: 373 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM---WEQVEKMREE 429
Query: 122 EKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVP 181
+K++ KK EEK E+ R+R + K +M+ E + R Q Q + +
Sbjct: 430 KKMQEQEKK---TRDQEEKMQEEERIREREK--KMREEEETMREQEEKMQKQEENMWEQE 484
Query: 182 REAWYWLRLEEETE---EDEEEKEQDEDEYKSED 212
+ W RL E+ E E E+ +EQ+E ++ E+
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 518
Score = 38.5 bits (88), Expect = 0.006
Identities = 41/202 (20%), Positives = 93/202 (46%), Gaps = 9/202 (4%)
Query: 26 LRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSG 85
+R+ R +E+K +E R++ K +EQE + + + + + ++ ++
Sbjct: 585 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQE 644
Query: 86 QALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESY--RKKIHMKNQAEEKAA- 142
+ + + + E L + K + + K +E+ E ++K+ K Q +EK
Sbjct: 645 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTW 704
Query: 143 EQFRMR----LKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDE 198
+Q +MR ++ ++ +M+ E ++ R Q +++ Q+ +E W + E+ E++E
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQE--EKMQEQEEKMQEQEEEMWEQEEKMWEQEE 762
Query: 199 EEKEQDEDEYKSEDLSVLEKLQ 220
+ EQ + E L EK+Q
Sbjct: 763 KMWEQQRLPEQKEKLWEHEKMQ 784
Score = 38.1 bits (87), Expect = 0.008
Identities = 42/218 (19%), Positives = 95/218 (43%), Gaps = 37/218 (16%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
M E+E+ M N+ E +Q R +KE+ ++ ++ +++ + E+E++ RD
Sbjct: 466 MREQEEKMQKQEENMWEQEEKEW---QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
+ + + K +KM + Q + + R
Sbjct: 523 ---QEEMWGQEKKMWRQEKMREQEDQ-----------------------MWEQEEKMRDQ 556
Query: 121 EEKLESYRKKIHMKNQAEEKAA----EQFR--MRLKNKQDEMKLEGDLRRSQRACQQLDV 174
E+K+ +++ K Q +EK E+ R R++ ++ +M+ E ++ R Q +++
Sbjct: 557 EQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE--EKMQE 614
Query: 175 QKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSED 212
Q+ +E W + E+ E++E+ EQ+E ++ E+
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 652
Score = 32.3 bits (72), Expect = 0.42
Identities = 46/228 (20%), Positives = 96/228 (42%), Gaps = 48/228 (21%)
Query: 3 EEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEK--QQEANLKNRQKSLKEEEQERRD 60
EEE + I QE+ M RQ R +E K +QE + ++K L+E+E+E R+
Sbjct: 278 EEELREQEKKIRKQEE-----KMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELRE 332
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
Q+ + + L + + E + + + R+
Sbjct: 333 -----------------QEKELREQKELREQEEQMQEQ--------EEKMWEQEEKMREQ 367
Query: 121 EEKLESYRKKI-----HMKNQAEEKAAEQFRM-----RLKNKQDEMKLEGDLRRSQRACQ 170
EEK+ +++ M+ Q ++ ++ RM RL+ K++ M R ++ +
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM------REQEKMWE 421
Query: 171 QLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEK 218
Q++ + + +E R +EE ++EE + E + + E+ ++ E+
Sbjct: 422 QVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQ 469
Score = 31.6 bits (70), Expect = 0.72
Identities = 38/192 (19%), Positives = 84/192 (43%), Gaps = 6/192 (3%)
Query: 29 IREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQAL 88
++E +RK E+ + L Q + +EE R++ L+ + K ++ ++ + L
Sbjct: 248 VKELKRKLERAKFL-LPQVQTNTLQEEMWRQEEELRE----QEKKIRKQEEKMWRQEERL 302
Query: 89 GKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMR 148
+ G + E + K E L R+ E++L ++ + Q +E+ + +
Sbjct: 303 REQEGKMREQEEKMWRQEKRLREQEKEL-REQEKELREQKELREQEEQMQEQEEKMWEQE 361
Query: 149 LKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEY 208
K ++ E K+ R +Q+ Q+ +E W + E E++E +EQ++
Sbjct: 362 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 421
Query: 209 KSEDLSVLEKLQ 220
+ E + +K+Q
Sbjct: 422 QVEKMREEKKMQ 433
>gi|56788356 tuftelin interacting protein 11 [Homo sapiens]
Length = 837
Score = 45.1 bits (105), Expect = 6e-05
Identities = 32/132 (24%), Positives = 64/132 (48%), Gaps = 12/132 (9%)
Query: 73 GFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIH 132
G LLQKMGY G+ LGK+ GI+ PI + GK +G S + + ++ +
Sbjct: 153 GQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGS--ERTTQSMQDFPVV-- 208
Query: 133 MKNQAEEKAAEQFRMRLKN-KQDEMKLEGDLRRSQRACQQLD----VQKNIQVPREAWYW 187
+EE+A E+F+ L ++D + + S + ++L + K + P++
Sbjct: 209 ---DSEEEAEEEFQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQ 265
Query: 188 LRLEEETEEDEE 199
+++ + T +++
Sbjct: 266 VKVIDMTGREQK 277
>gi|8393259 tuftelin interacting protein 11 [Homo sapiens]
Length = 837
Score = 45.1 bits (105), Expect = 6e-05
Identities = 32/132 (24%), Positives = 64/132 (48%), Gaps = 12/132 (9%)
Query: 73 GFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIH 132
G LLQKMGY G+ LGK+ GI+ PI + GK +G S + + ++ +
Sbjct: 153 GQKLLQKMGYVPGRGLGKNAQGIINPIEAKQRKGKGAVGAYGS--ERTTQSMQDFPVV-- 208
Query: 133 MKNQAEEKAAEQFRMRLKN-KQDEMKLEGDLRRSQRACQQLD----VQKNIQVPREAWYW 187
+EE+A E+F+ L ++D + + S + ++L + K + P++
Sbjct: 209 ---DSEEEAEEEFQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLTAPQKELSQ 265
Query: 188 LRLEEETEEDEE 199
+++ + T +++
Sbjct: 266 VKVIDMTGREQK 277
>gi|33469964 splicing factor 4 [Homo sapiens]
Length = 645
Score = 45.1 bits (105), Expect = 6e-05
Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 49 KSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKT--- 105
K+LKE + + L EN G+ +L KMG+K G+ LG G GI P+ T
Sbjct: 542 KALKEGREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGSEGQGIKNPVNKGTTTVDG 601
Query: 106 GKSGIGHEASLKRKAEEKLESYRKKI 131
GI A L K +++ E++RK++
Sbjct: 602 AGFGIDRPAELS-KEDDEYEAFRKRM 626
>gi|224282119 splicing factor, arginine/serine-rich 14 [Homo sapiens]
Length = 1082
Score = 44.7 bits (104), Expect = 8e-05
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 11/87 (12%)
Query: 45 KNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIK 104
K + K L +Q+ D +N GF +LQKMG+K G LG G GI EP+ ++
Sbjct: 996 KKKPKDLDFAQQKLTD---------KNLGFQMLQKMGWKEGHGLGSLGKGIREPV--SVG 1044
Query: 105 TGKSGIGHEASLKRKAEEKLESYRKKI 131
T G G A + E+ + +R+++
Sbjct: 1045 TPSEGEGLGADGQEHKEDTFDVFRQRM 1071
>gi|224282117 splicing factor, arginine/serine-rich 14 [Homo sapiens]
Length = 1082
Score = 44.7 bits (104), Expect = 8e-05
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 11/87 (12%)
Query: 45 KNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIK 104
K + K L +Q+ D +N GF +LQKMG+K G LG G GI EP+ ++
Sbjct: 996 KKKPKDLDFAQQKLTD---------KNLGFQMLQKMGWKEGHGLGSLGKGIREPV--SVG 1044
Query: 105 TGKSGIGHEASLKRKAEEKLESYRKKI 131
T G G A + E+ + +R+++
Sbjct: 1045 TPSEGEGLGADGQEHKEDTFDVFRQRM 1071
>gi|63003897 transcription factor NRF [Homo sapiens]
Length = 690
Score = 43.5 bits (101), Expect = 2e-04
Identities = 34/111 (30%), Positives = 53/111 (47%), Gaps = 13/111 (11%)
Query: 31 EARRKEEKQQEANLKNRQKSLKEEEQERRDI-------GLKNALGCENKGFALLQKMGYK 83
EA + +K Q + N +K E+ R +I K + +N G LL+KMG+
Sbjct: 506 EAVKTLKKTQPTVINNLKKGAVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWT 565
Query: 84 SGQALGKSGGGIVEPIPLNIKTGKSGIGHEAS-----LKRKAEEKLESYRK 129
G LGKSG GI EPI + + + G+G + KR E+ + +Y +
Sbjct: 566 GG-GLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYAR 615
>gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo
sapiens]
Length = 576
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/132 (21%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 118 RKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKN 177
RK +++++++RK + +N + + AE+ R + K KQ ++ + R Q +++K
Sbjct: 211 RKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLV---EQYREQSWMTMANLEKE 267
Query: 178 IQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCG 237
+Q EA Y + ++E+E E+ + +DE +D E ++ + LYC C
Sbjct: 268 LQ-EMEARYEKEFGDGSDENEMEEHELKDEEDGKDSDEAEDAELY------DDLYCPACD 320
Query: 238 TAYEDKEDLSSN 249
+++ ++ + ++
Sbjct: 321 KSFKTEKAMKNH 332
>gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo
sapiens]
Length = 531
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/132 (21%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 118 RKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKN 177
RK +++++++RK + +N + + AE+ R + K KQ ++ + R Q +++K
Sbjct: 211 RKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLV---EQYREQSWMTMANLEKE 267
Query: 178 IQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCG 237
+Q EA Y + ++E+E E+ + +DE +D E ++ + LYC C
Sbjct: 268 LQ-EMEARYEKEFGDGSDENEMEEHELKDEEDGKDSDEAEDAELY------DDLYCPACD 320
Query: 238 TAYEDKEDLSSN 249
+++ ++ + ++
Sbjct: 321 KSFKTEKAMKNH 332
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 42.7 bits (99), Expect = 3e-04
Identities = 54/260 (20%), Positives = 106/260 (40%), Gaps = 33/260 (12%)
Query: 13 INVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALG---C 69
++V +DI+P L ++ E + KE + EA + +++ + + E D G+ G C
Sbjct: 848 VDVTKDIKPQLELIED--EEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGEC 905
Query: 70 ENKGFAL--LQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESY 127
E L ++K G + G G E + ++G E + +AEE E
Sbjct: 906 EQTPEELEPVEKQGVDDIEKFEDEGAGFEE-------SSETGDYEEKAETEEAEEPEEDG 958
Query: 128 RKKI------HMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVP 181
+ + H + EE A + ++ K++ + GD R + + ++ + Q
Sbjct: 959 EEHVCVSASKHSPTEDEESAKAEADAYIREKRESVA-SGDDRAEEDMDEAIEKGEAEQS- 1016
Query: 182 REAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAYE 241
EEE +E+++ ++ E+EY+ E + + + + E G
Sbjct: 1017 ---------EEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTT 1067
Query: 242 DKEDLSSNCPG--PTSADHD 259
+ L + PG P S+ HD
Sbjct: 1068 PTKQLGAQSPGREPASSIHD 1087
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 42.4 bits (98), Expect = 4e-04
Identities = 45/209 (21%), Positives = 93/209 (44%), Gaps = 19/209 (9%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
M +E+ M + +E IR + + + R +EEK+QE Q+ K +EQE +
Sbjct: 332 MRRQEEMMWEK----EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE--KRQEQEAKM 385
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
+ + + + ++M + + +G+ + E + + + R+
Sbjct: 386 WRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQ--------EEEMQEQEEKMRRQ 437
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLD--VQKNI 178
EEK+ KKI + EEK EQ M + ++ + EG + + Q+ + +++
Sbjct: 438 EEKIREQEKKI---REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQE 494
Query: 179 QVPREAWYWLRLEEETEEDEEEKEQDEDE 207
+ RE +R +EE ++EE Q+++E
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQEE 523
Score = 40.8 bits (94), Expect = 0.001
Identities = 40/185 (21%), Positives = 83/185 (44%), Gaps = 25/185 (13%)
Query: 34 RKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGG 93
R+EEK QE K +++ K EQE + + + + + ++M ++ + + +
Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE--- 348
Query: 94 GIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQ 153
+ E + HE R+ EEK + +KI + + +E+ A+ +R K ++
Sbjct: 349 -LEEKM------------HEQEKIREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIRE 394
Query: 154 DEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDL 213
E K+ R Q Q +K + + W EEE +E EE+ + E++ + ++
Sbjct: 395 QEEKI-----REQEEMMQEQEEKMGEQEEKMW---EQEEEMQEQEEKMRRQEEKIREQEK 446
Query: 214 SVLEK 218
+ E+
Sbjct: 447 KIREQ 451
Score = 40.8 bits (94), Expect = 0.001
Identities = 46/220 (20%), Positives = 96/220 (43%), Gaps = 64/220 (29%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEK--QQEANLKNRQKSLKEEEQER 58
M E+E+ M + QE+ M Q E + +EEK +QE ++ ++K ++E+E++
Sbjct: 406 MQEQEEKMGE-----QEE-----KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455
Query: 59 RDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKR 118
R+ ++M + + +G+ G + E ++ + + R
Sbjct: 456 RE----------------QEEMMQEQEEKMGEQEGKMCEQ--------EAKMQEQEEKMR 491
Query: 119 KAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNI 178
+ EEK+ KKI + EEK EQ M +Q+E E + ++ C+Q
Sbjct: 492 RQEEKIREQEKKIR---EQEEKIREQEEMM--QEQEEKMWE----QEEKMCEQ------- 535
Query: 179 QVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEK 218
EE+ +E EE+ + E++ + +++ + ++
Sbjct: 536 ------------EEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
Score = 35.4 bits (80), Expect = 0.050
Identities = 40/189 (21%), Positives = 81/189 (42%), Gaps = 17/189 (8%)
Query: 36 EEKQQEANLKNRQK-SLKEEEQERRDIGLKNALG-CENKGFALLQKMGYKSGQALGKSGG 93
+E+ +E N K ++K L E E+ + +K E L Q+ LGK
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 263
Query: 94 GIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKN-- 151
+ + ++ + L ++ EEK+ +KI + + ++ E+ R + +
Sbjct: 264 SVSAKLQAQVEENELW----NRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMR 319
Query: 152 KQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSE 211
+Q+EM E + + ++ + ++ I+ LEE+ E E+ +EQ+E + E
Sbjct: 320 RQEEMMWEKEEKMRRQEEMMWEKEEKIR---------ELEEKMHEQEKIREQEEKRQEEE 370
Query: 212 DLSVLEKLQ 220
+ EK Q
Sbjct: 371 KIREQEKRQ 379
Score = 32.7 bits (73), Expect = 0.32
Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 17/114 (14%)
Query: 121 EEKLESYRKKIHMKN---QAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKN 177
EEK+ +K+H + + EEK E+ ++R + K+ E E + R Q+ +++
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ--EAKMWR-----QEEKIREQ 395
Query: 178 IQVPREAWYWLRLEEETEEDEEEK--EQDEDEYKSEDLSVLEKLQILTSYLREE 229
+ RE ++ +EE ++EEK EQ+E+ + E EK++ +RE+
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE-----EKMRRQEEKIREQ 444
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 42.0 bits (97), Expect = 5e-04
Identities = 39/185 (21%), Positives = 92/185 (49%), Gaps = 16/185 (8%)
Query: 28 QIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQA 87
Q+RE + + ++QE ++ ++ ++E+E + R+ + E +G +MG + GQ
Sbjct: 151 QVRE-QEGQVREQEGQVREQEGQVREQEGQVRE---QEGQVREQEG-----QMGEQEGQ- 200
Query: 88 LGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFR- 146
+G+ + E ++ + +G + RK EE++ +++ + + +K EQ R
Sbjct: 201 MGEQEEQMGEQEE-QMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRK 259
Query: 147 ----MRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKE 202
MR + +Q + E L++ ++ Q+ + + RE +R +EE ++EE+
Sbjct: 260 QEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
Query: 203 QDEDE 207
++++E
Sbjct: 320 REQEE 324
Score = 40.4 bits (93), Expect = 0.002
Identities = 38/190 (20%), Positives = 90/190 (47%), Gaps = 21/190 (11%)
Query: 28 QIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQA 87
Q+RE + + ++QE ++ ++ ++E+E + R+ + E +G ++ + GQ
Sbjct: 130 QVRE-QEGQVREQEGQVREQEGQVREQEGQVRE---QEGQVREQEG-----QVREQEGQV 180
Query: 88 LGKSGGGIVEPIPLNIKTGKSG-----IGHEASLKRKAEEKLESYRKKIHMKNQAEEKAA 142
+ G + + + G+ G +G + +K EE++ +++ + EE+
Sbjct: 181 REQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ---EEQMG 237
Query: 143 EQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKE 202
EQ K ++ K E +R+ + ++ + Q Q + L+ +E+TE++E+ E
Sbjct: 238 EQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQ----MLKQKEQTEQEEQTGE 293
Query: 203 QDEDEYKSED 212
Q+E + E+
Sbjct: 294 QEEQMREQEE 303
Score = 36.6 bits (83), Expect = 0.022
Identities = 42/214 (19%), Positives = 93/214 (43%), Gaps = 19/214 (8%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEE---EQE 57
M E+E+ + VQ+ Q+RE + +Q+E LK ++++ +EE EQE
Sbjct: 236 MGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQE 295
Query: 58 RRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLK 117
+ + + + + ++ + + +GK + E K + +
Sbjct: 296 EQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ--------KEQMWEQKEQM 347
Query: 118 RKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKN 177
K EE++ +++ + + K EQ R K ++ K E +R+ + +Q+ QK
Sbjct: 348 WKQEEQMGEQEEQMQKQEEQVRKQEEQMR---KQEEQMRKQEEQMRKQE---EQMGEQK- 400
Query: 178 IQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSE 211
+ E +R +EE +++E+ + ++E+ E
Sbjct: 401 -EQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGE 433
Score = 35.8 bits (81), Expect = 0.038
Identities = 42/212 (19%), Positives = 89/212 (41%), Gaps = 15/212 (7%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
M E+E+ M + +Q+ Q+R+ + +Q+E K ++ K+EEQ R+
Sbjct: 201 MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQ 260
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
E + ++M + Q L + E +TG+ ++
Sbjct: 261 ---------EEQMREQEEQMREQEEQMLKQK-----EQTEQEEQTGEQEEQMREQEEQMR 306
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRM-RLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQ 179
E++ + ++ M+ Q E+ ++ +M K + E K + + Q Q+ +QK +
Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEE 366
Query: 180 VPREAWYWLRLEEETEEDEEEKEQDEDEYKSE 211
R+ +R +EE +EE+ + ++E E
Sbjct: 367 QVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGE 398
>gi|110815815 centlein isoform 1 [Homo sapiens]
Length = 1406
Score = 41.6 bits (96), Expect = 7e-04
Identities = 61/244 (25%), Positives = 101/244 (41%), Gaps = 37/244 (15%)
Query: 9 SDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALG 68
SD + Q RP L L + +++ E + + LK + L E
Sbjct: 440 SDPDYSAQVPHRPSLSSLETLMVSQKSEIEYLQEKLKIANEKLSENISA----------- 488
Query: 69 CENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYR 128
NKGF+ M G+ + L+ K+ + E RKAE K+E+
Sbjct: 489 --NKGFSRKSIMTSAEGK---HKEPPVKRSRSLSPKSSFTD-SEELQKLRKAERKIENLE 542
Query: 129 KKIHMKNQ-------AEEKAAEQFRM-----RLKNKQDEMKLEG----DLRRSQRA-CQQ 171
K + +K+Q A EK E+ +M R +Q + EG ++R+ +RA QQ
Sbjct: 543 KALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQWEEGSGMTEIRKIKRADPQQ 602
Query: 172 LDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYK---SEDLSVLEKLQILTSYLRE 228
L + + V E Y+ R +E + E++ DE K S D + +++L + RE
Sbjct: 603 LRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHISIDKAAIQELNRCVAERRE 662
Query: 229 EHLY 232
E L+
Sbjct: 663 EQLF 666
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/204 (21%), Positives = 94/204 (46%), Gaps = 21/204 (10%)
Query: 25 MLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKS 84
M RQ + + EEK QE K R++ K EQE + + + + + ++M ++
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
Query: 85 GQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMK---NQAEEKA 141
+ + + + E + + + + + EEK+ +K+H + + EEK
Sbjct: 362 EEKMRRQEEMMWEK--------EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 413
Query: 142 AEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEED---- 197
E+ ++R + K+ E E + R + ++ + +K + ++ W R EE+ E
Sbjct: 414 QEEEKIREQEKRQEQ--EAKMWRQEEKIREQE-EKIREQEKKMW---RQEEKIHEQEKIR 467
Query: 198 EEEKEQDEDEYKSEDLSVLEKLQI 221
EEEK Q+++E ++ + E+ +I
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEI 491
Score = 38.5 bits (88), Expect = 0.006
Identities = 53/230 (23%), Positives = 100/230 (43%), Gaps = 28/230 (12%)
Query: 3 EEEDYMSDSFINVQEDI-RPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDI 61
+EE + + I+ QE+I R M Q + R++EEK K R++ K EQE +
Sbjct: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Query: 62 GLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAE 121
+ + + + + +KM + I + E + R+ E
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQE-----------------KIWEEEKRQEQEDKMWRQ-E 576
Query: 122 EKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVP 181
EK+ +K+ + EEK EQ R + ++ K E +R Q+ +Q+ +
Sbjct: 577 EKIREQEEKVWRQ---EEKIREQEEKRQEQEEKMWKQEEKIRE-----QEEKIQEQEEKI 628
Query: 182 REAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHL 231
RE +R +EE +++EEK +++E E +++ Q T + +EE +
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQE-QEETMWRQEEKI 677
Score = 37.4 bits (85), Expect = 0.013
Identities = 42/211 (19%), Positives = 96/211 (45%), Gaps = 10/211 (4%)
Query: 3 EEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIG 62
EE+ + + I QE++ + + + +E++Q++ + RQ+ E++E+
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQ 589
Query: 63 LKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEE 122
+ E K +KM +K + + + I E I+ + I + + ++ EE
Sbjct: 590 EEKIREQEEKRQEQEEKM-WKQEEKIREQEEKIQEQ-EEKIREQEEKIREQEEMTQEQEE 647
Query: 123 KL-ESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVP 181
K+ E K + + +E+ +R K ++ E K+ R Q +++ Q+ +
Sbjct: 648 KMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKI-----REQE--EKIREQEEMMQE 700
Query: 182 REAWYWLRLEEETEEDEEEKEQDEDEYKSED 212
+E W + E+ E++E+ +EQ+E + E+
Sbjct: 701 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Score = 36.6 bits (83), Expect = 0.022
Identities = 45/222 (20%), Positives = 94/222 (42%), Gaps = 30/222 (13%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEE----EQ 56
M +E+ + + +QE +IRE K +Q+E + +K ++E E+
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
Query: 57 ERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASL 116
E + + + + + ++M ++ + + + + E + HE
Sbjct: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE----LEEKM------------HEQEK 405
Query: 117 KRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQK 176
R+ EEK + +KI + + +E+ A+ +R K ++ E K+ ++ R +++ Q+
Sbjct: 406 IREQEEKRQE-EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 464
Query: 177 NI------QVPREAWYWLRLEEETEEDEEEKEQDEDEYKSED 212
I Q E W R EE+ E EE Q E ++ E+
Sbjct: 465 KIREEEKRQEQEEMW---RQEEKIHEQEEIWRQKEKMHEQEE 503
Score = 35.4 bits (80), Expect = 0.050
Identities = 38/178 (21%), Positives = 78/178 (43%), Gaps = 10/178 (5%)
Query: 3 EEEDYM--SDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
E+ED M + I QE+ + RQ + R +EEK+QE K ++ K EQE +
Sbjct: 567 EQEDKMWRQEEKIREQEE-----KVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLK--- 117
+ + + + ++M + + +G+ + E + ++ E ++
Sbjct: 622 QEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE 681
Query: 118 RKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQ 175
+K E+ E R++ M + EEK EQ + ++ + E +RR + + +V+
Sbjct: 682 KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739
Score = 35.0 bits (79), Expect = 0.065
Identities = 51/229 (22%), Positives = 89/229 (38%), Gaps = 52/229 (22%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
M E+E + QED M RQ + R +EEK K R++ K +EQE
Sbjct: 553 MHEQEKIWEEEKRQEQED-----KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE--- 604
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
+KM +K + + + I E + K
Sbjct: 605 -----------------EKM-WKQEEKIREQEEKIQEQ------------------EEKI 628
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQV 180
E+ E R++ M + EEK EQ + ++ + E + R + ++ + K I+
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQE--KKIRE 686
Query: 181 PREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREE 229
E +R +EE +++EEK +++E E EK+Q +R +
Sbjct: 687 QEEK---IREQEEMMQEQEEKMWEQEEKMCEQ---EEKMQEQEEKMRRQ 729
Score = 33.5 bits (75), Expect = 0.19
Identities = 36/120 (30%), Positives = 59/120 (49%), Gaps = 17/120 (14%)
Query: 118 RKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNK---QDEMKLEGDLRRSQ----RACQ 170
R+ EEK+ KK+ + EEK EQ ++R + K Q+EM + + Q R +
Sbjct: 440 REQEEKIREQEKKMWRQ---EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKE 496
Query: 171 QLDVQKNIQVPREAWYWLRLEEETEEDEEE-KEQDEDEYKSEDLSVLEKLQILTSYLREE 229
++ Q+ +E W R EE+ E EE+ +EQ+E ++ E EK++ REE
Sbjct: 497 KMHEQEEKIRKQEEKVW-RQEEKIREQEEKIREQEEKMWRQE-----EKIREQEEMWREE 550
Score = 32.0 bits (71), Expect = 0.55
Identities = 26/127 (20%), Positives = 60/127 (47%), Gaps = 9/127 (7%)
Query: 118 RKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRAC-------- 169
R+ E+K+ +KIH + + E+ Q + + +++++ + ++ R +
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIR 506
Query: 170 -QQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLRE 228
Q+ V + + RE +R +EE +EEK ++++E E+ + E+ +I R+
Sbjct: 507 KQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQ 566
Query: 229 EHLYCIW 235
E +W
Sbjct: 567 EQEDKMW 573
Score = 29.3 bits (64), Expect = 3.6
Identities = 26/114 (22%), Positives = 53/114 (46%), Gaps = 8/114 (7%)
Query: 119 KAEEKL---ESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQ 175
K +EKL ES + +I + + ++ E+ ++ L +Q L+ + + Q + +
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ----LQAEADHLGKELQSVSAK 280
Query: 176 KNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREE 229
QV E W RL ++ EE +E+ E++ + EK++ +RE+
Sbjct: 281 LQAQV-EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 41.2 bits (95), Expect = 0.001
Identities = 47/200 (23%), Positives = 90/200 (45%), Gaps = 12/200 (6%)
Query: 25 MLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKS 84
M RQ + + EEK QE K R++ K EQE + + + + + ++M ++
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
Query: 85 GQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQ 144
+ + + + E I+ + + HE R+ EEK + +KI + + +E+ A+
Sbjct: 362 EEKMRRLEEMMWEK-EEKIRELEEKM-HEQEKIREQEEKRQE-EEKIREQEKRQEQEAKM 418
Query: 145 FRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNI------QVPREAWYWLRLEEETEEDE 198
+R K ++ E K+ ++ R +++ Q+ I Q E W R EE+ E E
Sbjct: 419 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW---RQEEKIREQE 475
Query: 199 EEKEQDEDEYKSEDLSVLEK 218
E Q E ++ E + E+
Sbjct: 476 EIWRQKEKMHEQEKIRKQEE 495
Score = 38.1 bits (87), Expect = 0.008
Identities = 41/210 (19%), Positives = 95/210 (45%), Gaps = 12/210 (5%)
Query: 3 EEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEK--QQEANLKNRQKSLKEEE----- 55
+EE + + I QE+I + + + R++EEK +QE + ++++ ++E+E
Sbjct: 461 QEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR 520
Query: 56 QERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEAS 115
QE + + + + + ++M + + +G+ + E + + K I +
Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK--IREQEE 578
Query: 116 LKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQ 175
R+ +EK+ +KI + EEK EQ M + ++ + E + + Q+ + +
Sbjct: 579 KIREQKEKIREQEEKIW---EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 635
Query: 176 KNIQVPREAWYWLRLEEETEEDEEEKEQDE 205
Q + +RL ++ E+ +E +E E
Sbjct: 636 MRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 37.4 bits (85), Expect = 0.013
Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 20/201 (9%)
Query: 36 EEKQQEANLKNRQK-SLKEEEQERRDIGLKNALG-CENKGFALLQKMGYKSGQALGKSGG 93
+E+ +E N K ++K L E E+ + +K E L Q+ LGK
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 94 GIVEPIPLNIKTGK--SGIGHEASLKR-KAEEKLESYRKKIHMKNQAEEKAAEQFRMRLK 150
+ + ++ + + + + K + EEK++ + +KI + EEK EQ +++
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI---QEQEEKIREQ-EEKIR 331
Query: 151 NKQDEMKLEGDL----RRSQRACQQLDVQKNIQVPR-EAWYWLR------LEEETEEDEE 199
++++M+ + ++ R +++ +K ++ R E W + LEE+ E E+
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEK 391
Query: 200 EKEQDEDEYKSEDLSVLEKLQ 220
+EQ+E + E + EK Q
Sbjct: 392 IREQEEKRQEEEKIREQEKRQ 412
Score = 35.8 bits (81), Expect = 0.038
Identities = 44/215 (20%), Positives = 89/215 (41%), Gaps = 21/215 (9%)
Query: 4 EEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGL 63
EE I QE+ R +R+ + + +E K K R++ K EQE++
Sbjct: 383 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQ 442
Query: 64 KNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEK 123
+ + + K + ++ + + + + I E + + K HE RK EEK
Sbjct: 443 EEKIHEQEK---IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKM---HEQEKIRKQEEK 496
Query: 124 LESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPRE 183
+ +K+H EEK EQ + ++ + E +R + RE
Sbjct: 497 VWRQEEKMH---DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI------------RE 541
Query: 184 AWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEK 218
++ +EE ++EEK Q++++ + ++ + E+
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
Score = 35.4 bits (80), Expect = 0.050
Identities = 42/232 (18%), Positives = 99/232 (42%), Gaps = 33/232 (14%)
Query: 3 EEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIG 62
E++ + + I+ QE IR Q R++E+ +++ + +++ + E+E+ R+
Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ-- 493
Query: 63 LKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEE 122
E K + +KM + + I+ + + + R+ EE
Sbjct: 494 -------EEKVWRQEEKMHDQEEK----------------IREQEEKMWRQEEKIREQEE 530
Query: 123 KLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPR 182
K+ +KI + + ++ E+ + + Q++ K+ + + +++ QK +
Sbjct: 531 KIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Query: 183 EAWYW-----LRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREE 229
E W +R +EE +++EEK +++E E EK+Q +R +
Sbjct: 591 EEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQ---EEKMQEQEEKMRRQ 639
Score = 29.6 bits (65), Expect = 2.7
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 4/59 (6%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERR 59
M E+E+ M + +QE + M RQ + R +EEK +E K R++ K EQE +
Sbjct: 546 MQEQEEKMGEQEEKMQEQEK----MRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEK 600
Score = 29.3 bits (64), Expect = 3.6
Identities = 26/114 (22%), Positives = 53/114 (46%), Gaps = 8/114 (7%)
Query: 119 KAEEKL---ESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQ 175
K +EKL ES + +I + + ++ E+ ++ L +Q L+ + + Q + +
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ----LQAEADHLGKELQSVSAK 280
Query: 176 KNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREE 229
QV E W RL ++ EE +E+ E++ + EK++ +RE+
Sbjct: 281 LQAQV-EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 333
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/149 (21%), Positives = 72/149 (48%), Gaps = 12/149 (8%)
Query: 93 GGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNK 152
GG V +PL+ T + L++ KLE R++ M+ + EE+ ++ + +
Sbjct: 700 GGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ 759
Query: 153 QDEMKLEGDLRRSQRACQQLDVQKN---IQVPREAWYWLRLEEETEEDE---------EE 200
++ ++ + + R +R ++L +K ++ RE LR + E EE + EE
Sbjct: 760 EEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE 819
Query: 201 KEQDEDEYKSEDLSVLEKLQILTSYLREE 229
+ ++E+E + ++ + ++ + + REE
Sbjct: 820 RRREEEERRKQEELLRKQEEEAAKWAREE 848
Score = 38.1 bits (87), Expect = 0.008
Identities = 41/202 (20%), Positives = 93/202 (46%), Gaps = 36/202 (17%)
Query: 21 PGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKM 80
P L L+Q+ +A+ + +Q+ + R K +EEE+ +R L+ + +L++
Sbjct: 715 PALEQLQQLEKAKAAKLEQERREAEMRAK--REEEERKRQEELR------RQQEEILRRQ 766
Query: 81 GYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEK 140
+ + + + K E +L+R+ E+++ R++ + Q +E+
Sbjct: 767 QEEERKRREEE----------ELARRK----QEEALRRQREQEIALRRQREEEERQQQEE 812
Query: 141 AAEQFRMRLKNKQDEMKLEGDLRRSQR-----ACQQLDVQKNIQVPREAWYWLRLEEET- 194
A + R + +++ K E LR+ + A ++ + Q+ ++ R LR+EEE
Sbjct: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENR-----LRMEEEAA 867
Query: 195 ---EEDEEEKEQDEDEYKSEDL 213
E+EE K ++ + + ++L
Sbjct: 868 RLRHEEEERKRKELEVQRQKEL 889
Score = 37.0 bits (84), Expect = 0.017
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 20/122 (16%)
Query: 113 EASLKRKAEEKLESYRKK-IHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQ 171
E +RK EE L R++ I ++ Q EE+ +Q L+ ++ + E + R+ + ++
Sbjct: 777 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 836
Query: 172 LDVQKNIQVPREAWYWLRLEEET-----------EEDEEEKEQDEDEYKSEDLSVLEKLQ 220
+ EA W R EEE EE+ +E+E K ++L V + +
Sbjct: 837 QE--------EEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 888
Query: 221 IL 222
++
Sbjct: 889 LM 890
Score = 36.6 bits (83), Expect = 0.022
Identities = 39/192 (20%), Positives = 80/192 (41%), Gaps = 19/192 (9%)
Query: 29 IREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQAL 88
+R R +EE+QQ+ R + + EE+ERR K LL+K ++ +
Sbjct: 798 LRRQREEEERQQQEEALRRLEERRREEEERR------------KQEELLRKQEEEAAKWA 845
Query: 89 GKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMR 148
+ E ++ + + EA+ R EE E RK++ ++ Q E Q +
Sbjct: 846 REE-----EEAQRRLEENRLRMEEEAARLRHEEE--ERKRKELEVQRQKELMRQRQQQQE 898
Query: 149 LKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEY 208
+ + + + L + + Q++ ++ L L E + +EE + Q +E
Sbjct: 899 ALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 958
Query: 209 KSEDLSVLEKLQ 220
+ + +++ LQ
Sbjct: 959 RRQQRELMKALQ 970
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/149 (21%), Positives = 72/149 (48%), Gaps = 12/149 (8%)
Query: 93 GGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNK 152
GG V +PL+ T + L++ KLE R++ M+ + EE+ ++ + +
Sbjct: 727 GGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ 786
Query: 153 QDEMKLEGDLRRSQRACQQLDVQKN---IQVPREAWYWLRLEEETEEDE---------EE 200
++ ++ + + R +R ++L +K ++ RE LR + E EE + EE
Sbjct: 787 EEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE 846
Query: 201 KEQDEDEYKSEDLSVLEKLQILTSYLREE 229
+ ++E+E + ++ + ++ + + REE
Sbjct: 847 RRREEEERRKQEELLRKQEEEAAKWAREE 875
Score = 38.1 bits (87), Expect = 0.008
Identities = 41/202 (20%), Positives = 93/202 (46%), Gaps = 36/202 (17%)
Query: 21 PGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKM 80
P L L+Q+ +A+ + +Q+ + R K +EEE+ +R L+ + +L++
Sbjct: 742 PALEQLQQLEKAKAAKLEQERREAEMRAK--REEEERKRQEELR------RQQEEILRRQ 793
Query: 81 GYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEK 140
+ + + + K E +L+R+ E+++ R++ + Q +E+
Sbjct: 794 QEEERKRREEE----------ELARRK----QEEALRRQREQEIALRRQREEEERQQQEE 839
Query: 141 AAEQFRMRLKNKQDEMKLEGDLRRSQR-----ACQQLDVQKNIQVPREAWYWLRLEEET- 194
A + R + +++ K E LR+ + A ++ + Q+ ++ R LR+EEE
Sbjct: 840 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENR-----LRMEEEAA 894
Query: 195 ---EEDEEEKEQDEDEYKSEDL 213
E+EE K ++ + + ++L
Sbjct: 895 RLRHEEEERKRKELEVQRQKEL 916
Score = 37.0 bits (84), Expect = 0.017
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 20/122 (16%)
Query: 113 EASLKRKAEEKLESYRKK-IHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQ 171
E +RK EE L R++ I ++ Q EE+ +Q L+ ++ + E + R+ + ++
Sbjct: 804 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 863
Query: 172 LDVQKNIQVPREAWYWLRLEEET-----------EEDEEEKEQDEDEYKSEDLSVLEKLQ 220
+ EA W R EEE EE+ +E+E K ++L V + +
Sbjct: 864 QE--------EEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 915
Query: 221 IL 222
++
Sbjct: 916 LM 917
Score = 36.6 bits (83), Expect = 0.022
Identities = 39/192 (20%), Positives = 80/192 (41%), Gaps = 19/192 (9%)
Query: 29 IREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQAL 88
+R R +EE+QQ+ R + + EE+ERR K LL+K ++ +
Sbjct: 825 LRRQREEEERQQQEEALRRLEERRREEEERR------------KQEELLRKQEEEAAKWA 872
Query: 89 GKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMR 148
+ E ++ + + EA+ R EE E RK++ ++ Q E Q +
Sbjct: 873 REE-----EEAQRRLEENRLRMEEEAARLRHEEE--ERKRKELEVQRQKELMRQRQQQQE 925
Query: 149 LKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEY 208
+ + + + L + + Q++ ++ L L E + +EE + Q +E
Sbjct: 926 ALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 985
Query: 209 KSEDLSVLEKLQ 220
+ + +++ LQ
Sbjct: 986 RRQQRELMKALQ 997
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/149 (21%), Positives = 72/149 (48%), Gaps = 12/149 (8%)
Query: 93 GGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNK 152
GG V +PL+ T + L++ KLE R++ M+ + EE+ ++ + +
Sbjct: 706 GGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ 765
Query: 153 QDEMKLEGDLRRSQRACQQLDVQKN---IQVPREAWYWLRLEEETEEDE---------EE 200
++ ++ + + R +R ++L +K ++ RE LR + E EE + EE
Sbjct: 766 EEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE 825
Query: 201 KEQDEDEYKSEDLSVLEKLQILTSYLREE 229
+ ++E+E + ++ + ++ + + REE
Sbjct: 826 RRREEEERRKQEELLRKQEEEAAKWAREE 854
Score = 38.1 bits (87), Expect = 0.008
Identities = 41/202 (20%), Positives = 93/202 (46%), Gaps = 36/202 (17%)
Query: 21 PGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKM 80
P L L+Q+ +A+ + +Q+ + R K +EEE+ +R L+ + +L++
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAK--REEEERKRQEELR------RQQEEILRRQ 772
Query: 81 GYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEK 140
+ + + + K E +L+R+ E+++ R++ + Q +E+
Sbjct: 773 QEEERKRREEE----------ELARRK----QEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 141 AAEQFRMRLKNKQDEMKLEGDLRRSQR-----ACQQLDVQKNIQVPREAWYWLRLEEET- 194
A + R + +++ K E LR+ + A ++ + Q+ ++ R LR+EEE
Sbjct: 819 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENR-----LRMEEEAA 873
Query: 195 ---EEDEEEKEQDEDEYKSEDL 213
E+EE K ++ + + ++L
Sbjct: 874 RLRHEEEERKRKELEVQRQKEL 895
Score = 37.0 bits (84), Expect = 0.017
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 20/122 (16%)
Query: 113 EASLKRKAEEKLESYRKK-IHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQ 171
E +RK EE L R++ I ++ Q EE+ +Q L+ ++ + E + R+ + ++
Sbjct: 783 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 842
Query: 172 LDVQKNIQVPREAWYWLRLEEET-----------EEDEEEKEQDEDEYKSEDLSVLEKLQ 220
+ EA W R EEE EE+ +E+E K ++L V + +
Sbjct: 843 QE--------EEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 894
Query: 221 IL 222
++
Sbjct: 895 LM 896
Score = 36.6 bits (83), Expect = 0.022
Identities = 39/192 (20%), Positives = 80/192 (41%), Gaps = 19/192 (9%)
Query: 29 IREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQAL 88
+R R +EE+QQ+ R + + EE+ERR K LL+K ++ +
Sbjct: 804 LRRQREEEERQQQEEALRRLEERRREEEERR------------KQEELLRKQEEEAAKWA 851
Query: 89 GKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMR 148
+ E ++ + + EA+ R EE E RK++ ++ Q E Q +
Sbjct: 852 REE-----EEAQRRLEENRLRMEEEAARLRHEEE--ERKRKELEVQRQKELMRQRQQQQE 904
Query: 149 LKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEY 208
+ + + + L + + Q++ ++ L L E + +EE + Q +E
Sbjct: 905 ALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 964
Query: 209 KSEDLSVLEKLQ 220
+ + +++ LQ
Sbjct: 965 RRQQRELMKALQ 976
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/149 (21%), Positives = 72/149 (48%), Gaps = 12/149 (8%)
Query: 93 GGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNK 152
GG V +PL+ T + L++ KLE R++ M+ + EE+ ++ + +
Sbjct: 706 GGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQ 765
Query: 153 QDEMKLEGDLRRSQRACQQLDVQKN---IQVPREAWYWLRLEEETEEDE---------EE 200
++ ++ + + R +R ++L +K ++ RE LR + E EE + EE
Sbjct: 766 EEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEE 825
Query: 201 KEQDEDEYKSEDLSVLEKLQILTSYLREE 229
+ ++E+E + ++ + ++ + + REE
Sbjct: 826 RRREEEERRKQEELLRKQEEEAAKWAREE 854
Score = 38.1 bits (87), Expect = 0.008
Identities = 41/202 (20%), Positives = 93/202 (46%), Gaps = 36/202 (17%)
Query: 21 PGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKM 80
P L L+Q+ +A+ + +Q+ + R K +EEE+ +R L+ + +L++
Sbjct: 721 PALEQLQQLEKAKAAKLEQERREAEMRAK--REEEERKRQEELR------RQQEEILRRQ 772
Query: 81 GYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEK 140
+ + + + K E +L+R+ E+++ R++ + Q +E+
Sbjct: 773 QEEERKRREEE----------ELARRK----QEEALRRQREQEIALRRQREEEERQQQEE 818
Query: 141 AAEQFRMRLKNKQDEMKLEGDLRRSQR-----ACQQLDVQKNIQVPREAWYWLRLEEET- 194
A + R + +++ K E LR+ + A ++ + Q+ ++ R LR+EEE
Sbjct: 819 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENR-----LRMEEEAA 873
Query: 195 ---EEDEEEKEQDEDEYKSEDL 213
E+EE K ++ + + ++L
Sbjct: 874 RLRHEEEERKRKELEVQRQKEL 895
Score = 37.0 bits (84), Expect = 0.017
Identities = 29/122 (23%), Positives = 55/122 (45%), Gaps = 20/122 (16%)
Query: 113 EASLKRKAEEKLESYRKK-IHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQ 171
E +RK EE L R++ I ++ Q EE+ +Q L+ ++ + E + R+ + ++
Sbjct: 783 EELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK 842
Query: 172 LDVQKNIQVPREAWYWLRLEEET-----------EEDEEEKEQDEDEYKSEDLSVLEKLQ 220
+ EA W R EEE EE+ +E+E K ++L V + +
Sbjct: 843 QE--------EEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 894
Query: 221 IL 222
++
Sbjct: 895 LM 896
Score = 36.6 bits (83), Expect = 0.022
Identities = 39/192 (20%), Positives = 80/192 (41%), Gaps = 19/192 (9%)
Query: 29 IREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQAL 88
+R R +EE+QQ+ R + + EE+ERR K LL+K ++ +
Sbjct: 804 LRRQREEEERQQQEEALRRLEERRREEEERR------------KQEELLRKQEEEAAKWA 851
Query: 89 GKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMR 148
+ E ++ + + EA+ R EE E RK++ ++ Q E Q +
Sbjct: 852 REE-----EEAQRRLEENRLRMEEEAARLRHEEE--ERKRKELEVQRQKELMRQRQQQQE 904
Query: 149 LKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEY 208
+ + + + L + + Q++ ++ L L E + +EE + Q +E
Sbjct: 905 ALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQ 964
Query: 209 KSEDLSVLEKLQ 220
+ + +++ LQ
Sbjct: 965 RRQQRELMKALQ 976
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 41.2 bits (95), Expect = 0.001
Identities = 49/217 (22%), Positives = 94/217 (43%), Gaps = 48/217 (22%)
Query: 3 EEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEK--QQEANLKNRQKSLKEEEQERRD 60
EEE + I QE+ M RQ R +E K +QE ++ ++K L+E+E+E R+
Sbjct: 240 EEELREQEKKIRKQEE-----KMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE 294
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
+ K +K+ + Q ++ + + + R+
Sbjct: 295 ---------QEKELREQKKLREQEEQ----------------MQEQEEKMWEQEEKMREQ 329
Query: 121 EEKLESYRKKI-----HMKNQAEEKAAEQFRM-----RLKNKQDEMKLEGDLRRSQRACQ 170
EEK+ +++ M+ Q ++ ++ RM RL+ K++ M R ++ +
Sbjct: 330 EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM------REQEKMWE 383
Query: 171 QLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDE 207
Q + + + RE +R EEET ++EEK Q ++E
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
Score = 36.6 bits (83), Expect = 0.022
Identities = 41/201 (20%), Positives = 88/201 (43%), Gaps = 6/201 (2%)
Query: 29 IREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQAL 88
++E +RK E+ + L Q + +EE R++ L+ + K ++ ++ + L
Sbjct: 210 VKELKRKLERAKFL-LPQVQTNTLQEEMWRQEEELRE----QEKKIRKQEEKMWRQEERL 264
Query: 89 GKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMR 148
+ G + E + K E L R+ E++L +K + Q +E+ + +
Sbjct: 265 REQEGKMREQEEKMRRQEKRLREQEKEL-REQEKELREQKKLREQEEQMQEQEEKMWEQE 323
Query: 149 LKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEY 208
K ++ E K+ R +Q+ Q+ +E W + E E++E +EQ++
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 383
Query: 209 KSEDLSVLEKLQILTSYLREE 229
+ E + E+++ +REE
Sbjct: 384 QEEKMQEEERIREREKKMREE 404
Score = 35.8 bits (81), Expect = 0.038
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 117 KRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQK 176
K + E+K + KK EEK E+ RMR + K+ M+ E ++ R Q Q +K
Sbjct: 535 KMREEKKTQEQEKKTW---DQEEKMREEERMREREKK--MREEEEMMREQEEKMQEQEEK 589
Query: 177 NIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSED 212
+ + W +E EE E+E+ E + ED
Sbjct: 590 MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Score = 35.4 bits (80), Expect = 0.050
Identities = 48/212 (22%), Positives = 96/212 (45%), Gaps = 20/212 (9%)
Query: 1 MAEEEDYMSDSFINVQE---DIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQE 57
M E+E+ M ++E ++R LR+ ++ R +EE+ QE K ++ K EQE
Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 58 RRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLK 117
+ + L + K ++ + + + + E + K E K
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMW---EQEEK 387
Query: 118 RKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKN 177
+ EE++ KK M+ + E ++ +M+ KQ+E E + + Q+ Q+L QK
Sbjct: 388 MQEEERIREREKK--MREEEETMREQEEKMQ---KQEENMWEQEEKEWQQ--QRLPEQK- 439
Query: 178 IQVPREAWYWLRLEEETEE--DEEEKEQDEDE 207
+ W +++E+ E+ ++EEK +D++E
Sbjct: 440 ----EKLWEQEKMQEQEEKIWEQEEKIRDQEE 467
Score = 33.5 bits (75), Expect = 0.19
Identities = 42/205 (20%), Positives = 90/205 (43%), Gaps = 11/205 (5%)
Query: 3 EEEDYMSDSFINVQEDIRPGLPMLRQIREA-RRKEEKQQEANLKNRQKSLKEEEQERRDI 61
E++ + + + +E +R +R+ E R +EEK QE K R++ K EQE +
Sbjct: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK-- 603
Query: 62 GLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAE 121
E K + +KM + + + ++ ++ + + + R+ E
Sbjct: 604 ----MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE 659
Query: 122 EKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVP 181
EK+ +K M+ Q EEK EQ +++ ++++M+ + + R Q +K
Sbjct: 660 EKMREQEEK--MQGQ-EEKMREQ-EEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQE 715
Query: 182 REAWYWLRLEEETEEDEEEKEQDED 206
+ W + E+ E ++KE+ ++
Sbjct: 716 EKMWGQEEMREKEERIRDQKEKMQE 740
Score = 32.7 bits (73), Expect = 0.32
Identities = 36/186 (19%), Positives = 82/186 (44%), Gaps = 24/186 (12%)
Query: 26 LRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSG 85
LR+ E R+++K + K R++ K +EQE++ + + E + +KM +
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEK-KTQEQEKKTWDQEEKMREEERMREREKKMREEEE 574
Query: 86 QALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQA----EEKA 141
++ + + + R+ EEK+ +K+ + + EEK
Sbjct: 575 M----------------MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKM 618
Query: 142 AEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEK 201
EQ +Q+EM E + + ++ + + ++ ++ E +R +EE + +EEK
Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEK---MREQEEKMQGQEEK 675
Query: 202 EQDEDE 207
++++E
Sbjct: 676 MREQEE 681
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 41.2 bits (95), Expect = 0.001
Identities = 54/233 (23%), Positives = 100/233 (42%), Gaps = 40/233 (17%)
Query: 3 EEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEK--QQEANLKNRQKSLKEEEQERRD 60
EE+ + + I+ QE IR Q E R+EEK +QE + ++K ++EE+ R+
Sbjct: 497 EEKMWRQEEKIHEQEKIREEEKRQEQ-EEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
E K + +KM + + I+ + + + R+
Sbjct: 556 ---------EEKMWRQEEKMHDQEEK----------------IREQEEKVWRQEEKIREQ 590
Query: 121 EEKLESYRKKIH----MKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQK 176
EEK+ +KI M + EEK EQ + ++ + E +RR + ++ + K
Sbjct: 591 EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE--K 648
Query: 177 NIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREE 229
I+ E +R +EE +++EEK +++E E EK+Q +R +
Sbjct: 649 KIREQEEK---IREQEEMMQEQEEKMWEQEEKMCEQ---EEKMQEQEEKMRRQ 695
Score = 40.8 bits (94), Expect = 0.001
Identities = 46/194 (23%), Positives = 87/194 (44%), Gaps = 12/194 (6%)
Query: 25 MLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKS 84
M RQ + + EEK QE K R++ K EQE + + + + + ++M ++
Sbjct: 363 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 422
Query: 85 GQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQ 144
+ + + + E I+ + + HE R+ EEK + +KI + + +E+ A+
Sbjct: 423 EEKMRRQEEMMWEK-EEKIRELEEKM-HEQEKIREQEEKRQE-EEKIREQEKRQEQEAKM 479
Query: 145 FRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNI------QVPREAWYWLRLEEETEEDE 198
+R K ++ E K+ + R +++ Q+ I Q E W R EE+ E E
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW---RQEEKIREQE 536
Query: 199 EEKEQDEDEYKSED 212
E Q E ++ E+
Sbjct: 537 EIWRQKEKIHEQEE 550
Score = 37.4 bits (85), Expect = 0.013
Identities = 44/201 (21%), Positives = 91/201 (45%), Gaps = 20/201 (9%)
Query: 36 EEKQQEANLKNRQK-SLKEEEQERRDIGLKNALG-CENKGFALLQKMGYKSGQALGKSGG 93
+E+ +E N K ++K L E E+ + +K E L Q+ LGK
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 336
Query: 94 GIVEPIPLNIKTGK--SGIGHEASLKR-KAEEKLESYRKKIHMKNQAEEKAAEQFRMRLK 150
+ + ++ + + + + K + EEK++ + +KI + EEK EQ +++
Sbjct: 337 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKI---QEQEEKIREQ-EEKIR 392
Query: 151 NKQDEMKLEGDL----RRSQRACQQLDVQKNIQVPR-EAWYWLR------LEEETEEDEE 199
++++M+ + ++ R +++ +K ++ R E W + LEE+ E E+
Sbjct: 393 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK 452
Query: 200 EKEQDEDEYKSEDLSVLEKLQ 220
+EQ+E + E + EK Q
Sbjct: 453 IREQEEKRQEEEKIREQEKRQ 473
Score = 35.8 bits (81), Expect = 0.038
Identities = 31/128 (24%), Positives = 60/128 (46%), Gaps = 12/128 (9%)
Query: 113 EASLKRKAE---EKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRAC 169
E ++R+ E EK E R++ M + EEK Q M + ++ +LE + ++
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454
Query: 170 QQLDVQKNIQVPRE--------AWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQI 221
+Q + ++ + RE A W R EE+ E EE+ + E++ ++ + E+ +I
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMW-RQEEKIREQEEKIREQEEKMWRQEEKIHEQEKI 513
Query: 222 LTSYLREE 229
R+E
Sbjct: 514 REEEKRQE 521
Score = 35.0 bits (79), Expect = 0.065
Identities = 48/201 (23%), Positives = 93/201 (46%), Gaps = 19/201 (9%)
Query: 16 QEDIRPGLPMLRQIREARRKEEK---QQEANLKNRQKSL--KEEEQERRDIGLKNALGCE 70
+E IR +R+ E R++E+ ++E ++ +++ + KEE+ R++ + E
Sbjct: 381 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK---E 437
Query: 71 NKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKK 130
K L +KM + + E I K + EA + R+ EEK+ +K
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ----EAKMWRQ-EEKIREQEEK 492
Query: 131 IHMKNQA----EEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWY 186
I + + EEK EQ ++R + K+ E E R+ ++ +Q ++ + + E
Sbjct: 493 IREQEEKMWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIREQEEIWRQKEKIHEQEE 550
Query: 187 WLRLEEETEEDEEEKEQDEDE 207
+R +EE +EEK D++E
Sbjct: 551 KIRKQEEKMWRQEEKMHDQEE 571
Score = 34.7 bits (78), Expect = 0.085
Identities = 41/209 (19%), Positives = 92/209 (44%), Gaps = 23/209 (11%)
Query: 3 EEEDYMSDSFINVQEDI-RPGLPMLRQIREARRKEEK--QQEANLKNRQKSLKEEE---- 55
+EE + + I QE+I R + Q + R++EEK +QE + ++++ ++E+E
Sbjct: 522 QEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVW 581
Query: 56 -QERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEA 114
QE + + + + + ++M + + +G+ + E + + E
Sbjct: 582 RQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 115 SLK---RKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQ 171
++ +K E+ E R++ M + EEK EQ + ++ + E +RR + +
Sbjct: 642 KIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWE 701
Query: 172 LDVQKNIQVPREAWYWLRLEEETEEDEEE 200
+V+ LR +EE ++ +E
Sbjct: 702 QEVR------------LRQQEEKMQEHQE 718
Score = 31.2 bits (69), Expect = 0.94
Identities = 43/205 (20%), Positives = 78/205 (38%), Gaps = 42/205 (20%)
Query: 1 MAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRD 60
M +E+ M D ++E +IRE K +Q+E K R++ +EQE +
Sbjct: 559 MWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE---KIREQEEMTQEQEEK- 614
Query: 61 IGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKA 120
+G + CE + +KM + R+
Sbjct: 615 MGEQEEKMCEQE-----EKM------------------------------QEQEEKMRRQ 639
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQV 180
EEK+ KKI + EEK EQ M + ++ + E + + Q+ + + Q
Sbjct: 640 EEKIREQEKKI---REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Query: 181 PREAWYWLRLEEETEEDEEEKEQDE 205
+ +RL ++ E+ +E +E E
Sbjct: 697 EKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 29.3 bits (64), Expect = 3.6
Identities = 26/114 (22%), Positives = 53/114 (46%), Gaps = 8/114 (7%)
Query: 119 KAEEKL---ESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQ 175
K +EKL ES + +I + + ++ E+ ++ L +Q L+ + + Q + +
Sbjct: 286 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ----LQAEADHLGKELQSVSAK 341
Query: 176 KNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREE 229
QV E W RL ++ EE +E+ E++ + EK++ +RE+
Sbjct: 342 LQAQV-EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ 394
>gi|4502395 beclin 1 [Homo sapiens]
Length = 450
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/109 (28%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 121 EEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQL-DVQKNIQ 179
E + ++Y++ + + Q E +EQ +M LK E+ LE +R Q+L DV+KN +
Sbjct: 156 ENECQNYKRCLEILEQMNEDDSEQLQMELK----ELALE-----EERLIQELEDVEKNRK 206
Query: 180 VPREAWYWLRLEEETEEDEEEKEQDE-DEYKSEDLSVLEKLQILTSYLR 227
+ E ++ E E + EE + Q E E+K + L + ++L+ + + +R
Sbjct: 207 IVAENLEKVQAEAERLDQEEAQYQREYSEFKRQQLELDDELKSVENQMR 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,575,437
Number of Sequences: 37866
Number of extensions: 535742
Number of successful extensions: 14397
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 345
Number of HSP's successfully gapped in prelim test: 439
Number of HSP's that attempted gapping in prelim test: 6834
Number of HSP's gapped (non-prelim): 4721
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.