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Search of human proteins with 167860120
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167860120 phospholipase A2, group IVB [Homo sapiens]
(781 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167860120 phospholipase A2, group IVB [Homo sapiens] 1596 0.0
gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens] 1592 0.0
gi|116174754 phospholipase A2, group IVD [Homo sapiens] 766 0.0
gi|122937428 phospholipase A2, group 4E [Homo sapiens] 628 e-180
gi|67972429 phospholipase A2, group IVF [Homo sapiens] 584 e-167
gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens] 241 2e-63
gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens] 165 1e-40
gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Ho... 165 1e-40
gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Ho... 165 1e-40
gi|38570146 synaptotagmin VII [Homo sapiens] 57 9e-08
gi|222352090 neural precursor cell expressed, developmentally do... 54 7e-07
gi|222352088 neural precursor cell expressed, developmentally do... 54 7e-07
gi|45504376 synaptotagmin VI [Homo sapiens] 54 7e-07
gi|21361472 neural precursor cell expressed, developmentally dow... 53 9e-07
gi|222352086 neural precursor cell expressed, developmentally do... 53 9e-07
gi|114520609 neural precursor cell expressed, developmentally do... 52 2e-06
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva... 51 5e-06
gi|239743307 PREDICTED: similar to calcium-promoted Ras inactiva... 51 5e-06
gi|239508992 PREDICTED: similar to calcium-promoted Ras inactiva... 51 5e-06
gi|239508990 PREDICTED: similar to calcium-promoted Ras inactiva... 51 5e-06
gi|121114292 RAS p21 protein activator 4 isoform 2 [Homo sapiens] 51 5e-06
gi|121114294 RAS p21 protein activator 4 isoform 1 [Homo sapiens] 51 5e-06
gi|122937247 unc-13 homolog A [Homo sapiens] 50 6e-06
gi|110611226 UNC13 (C. elegans)-like [Homo sapiens] 49 2e-05
gi|122937514 unc-13 homolog C [Homo sapiens] 48 3e-05
gi|39752671 synaptotagmin X [Homo sapiens] 48 3e-05
gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Hom... 47 5e-05
gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Hom... 47 5e-05
gi|227496504 multiple C2 domains, transmembrane 2 isoform 3 [Hom... 47 5e-05
gi|238550198 synaptotagmin III [Homo sapiens] 45 2e-04
>gi|167860120 phospholipase A2, group IVB [Homo sapiens]
Length = 781
Score = 1596 bits (4132), Expect = 0.0
Identities = 781/781 (100%), Positives = 781/781 (100%)
Query: 1 MAVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW 60
MAVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW
Sbjct: 1 MAVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW 60
Query: 61 NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG 120
NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG
Sbjct: 61 NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG 120
Query: 121 RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP 180
RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP
Sbjct: 121 RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP 180
Query: 181 QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR 240
QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR
Sbjct: 181 QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR 240
Query: 241 VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM 300
VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM
Sbjct: 241 VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM 300
Query: 301 ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE 360
ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE
Sbjct: 301 ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE 360
Query: 361 LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS 420
LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS
Sbjct: 361 LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS 420
Query: 421 DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF 480
DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF
Sbjct: 421 DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF 480
Query: 481 FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL 540
FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL
Sbjct: 481 FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL 540
Query: 541 LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL 600
LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL
Sbjct: 541 LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL 600
Query: 601 PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE 660
PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE
Sbjct: 601 PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE 660
Query: 661 QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA 720
QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA
Sbjct: 661 QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA 720
Query: 721 AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP 780
AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP
Sbjct: 721 AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP 780
Query: 781 H 781
H
Sbjct: 781 H 781
>gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]
Length = 1012
Score = 1592 bits (4121), Expect = 0.0
Identities = 779/781 (99%), Positives = 779/781 (99%)
Query: 1 MAVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW 60
M AEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW
Sbjct: 232 MEKAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW 291
Query: 61 NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG 120
NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG
Sbjct: 292 NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG 351
Query: 121 RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP 180
RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP
Sbjct: 352 RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP 411
Query: 181 QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR 240
QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR
Sbjct: 412 QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR 471
Query: 241 VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM 300
VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM
Sbjct: 472 VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM 531
Query: 301 ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE 360
ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE
Sbjct: 532 ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE 591
Query: 361 LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS 420
LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS
Sbjct: 592 LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS 651
Query: 421 DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF 480
DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF
Sbjct: 652 DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF 711
Query: 481 FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL 540
FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL
Sbjct: 712 FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL 771
Query: 541 LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL 600
LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL
Sbjct: 772 LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL 831
Query: 601 PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE 660
PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE
Sbjct: 832 PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE 891
Query: 661 QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA 720
QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA
Sbjct: 892 QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA 951
Query: 721 AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP 780
AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP
Sbjct: 952 AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP 1011
Query: 781 H 781
H
Sbjct: 1012 H 1012
>gi|116174754 phospholipase A2, group IVD [Homo sapiens]
Length = 818
Score = 766 bits (1978), Expect = 0.0
Identities = 403/795 (50%), Positives = 531/795 (66%), Gaps = 28/795 (3%)
Query: 5 EVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSF 64
E S LTVRVL+A L DL++ +D YV L L TA + +T+T+ ++S PVWN++F
Sbjct: 17 EASTCWQLTVRVLEARNLRWADLLSEADPYVILQLSTAPGMKFKTKTLTDTSHPVWNEAF 76
Query: 65 HFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEV 124
F I Q+KNV+EL ++D+D VT DD VL+D + G+ R++FS SPQGE L+V
Sbjct: 77 RFLIQSQVKNVLELSIYDEDSVTEDDICFKVLYDISEVLPGKLLRKTFSQSPQGEEELDV 136
Query: 125 EFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETG------DQKSSEHRVQLVVPGSCE 178
EF ++ +DR E L++N V+VARELSCL V L+ TG DQ E ++LV+ GS E
Sbjct: 137 EFLMEETSDRPENLITNKVIVARELSCLDVHLDSTGSTAVVADQDKLE--LELVLKGSYE 194
Query: 179 GPQEASVGTGT-FRFHCPACWEQELSIRLQ---------DAPEEQLKAPLSALPSGQVVR 228
Q + +GT + FRFH A E ELS RL+ D L PL L G+ V
Sbjct: 195 DTQTSFLGTASAFRFHYMAALETELSGRLRSSRSNGWNGDNSAGYLTVPLRPLTIGKEVT 254
Query: 229 LVFPTSQEPLMRVELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGD 288
+ P P +R++LK E ELAV LGF CAEEQAFLSRRKQVVA AL+QALQLD D
Sbjct: 255 MDVPAPNAPGVRLQLKAEGCPEELAVHLGFNLCAEEQAFLSRRKQVVAKALKQALQLDRD 314
Query: 289 LQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDP 348
LQEDE+PVV IMATGGG RAMTSLYG L L++LGLLDCV+Y +G SGSTW +A+LY DP
Sbjct: 315 LQEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYGDP 374
Query: 349 EWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEA 408
EWSQ+DL GP + + K+KL V +P +L YR+EL RA G+P+ F +LWAL+ E+
Sbjct: 375 EWSQRDLEGPIRYAREHLAKSKLEVFSPERLASYRRELELRAEQGHPTTFVDLWALVLES 434
Query: 409 LLHDEPHDHKLSDQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYG 468
+LH + D KLS QR AL GQNPLP+Y +LN K +L T +F EW EFSPYEVGF KYG
Sbjct: 435 MLHGQVMDQKLSGQRAALERGQNPLPLYLSLNVKENNLETLDFKEWVEFSPYEVGFLKYG 494
Query: 469 AFIPSELFGSEFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVR 528
AF+P ELFGSEFFMG+LM+R+PE RICFLE IWSN+++ NL D+ Y + + W + ++
Sbjct: 495 AFVPPELFGSEFFMGRLMRRIPEPRICFLEAIWSNIFSLNLLDAWYDLTSSGESWKQHIK 554
Query: 529 NQA-NLDKEQVPLLKIEE-------PPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFH 580
++ +L+KE + P TA +A+ F LT RPL Q + NFL+GL H
Sbjct: 555 DKTRSLEKEPLTTSGTSSRLEASWLQPGTA--LAQAFKGFLTGRPLHQRSPNFLQGLQLH 612
Query: 581 KDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSL 640
+DY H FSTW LD +P+QLTP EP LCL+D Y INTS + +P R +DLILS
Sbjct: 613 QDYCSHKDFSTWADYQLDSMPSQLTPKEPRLCLVDAAYFINTSSPSMFRPGRRLDLILSF 672
Query: 641 DYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPL 700
DY+L F+ LQ +C+ +G+PFP + PSP++Q QPRECH FSDP CP AP +LHFPL
Sbjct: 673 DYSLSAPFEALQQTELYCRARGLPFPRVEPSPQDQHQPRECHLFSDPACPEAPILLHFPL 732
Query: 701 VSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNN 760
V+ SF+++SAPGV+R+P E G+V+L+ + PY + +TY +ED ++LL L+ YNV +
Sbjct: 733 VNASFKDHSAPGVQRSPAELQGGQVDLTGATCPYTLSNMTYKEEDFERLLRLSDYNVQTS 792
Query: 761 QEQLLEALRQAVQRR 775
Q +L+ALR A++ R
Sbjct: 793 QGAILQALRTALKHR 807
>gi|122937428 phospholipase A2, group 4E [Homo sapiens]
Length = 839
Score = 628 bits (1619), Expect = e-180
Identities = 346/786 (44%), Positives = 476/786 (60%), Gaps = 46/786 (5%)
Query: 28 VTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVT 87
V+ +DC+V+LWLPTA +L+TRT+ N +P WN+SF+F+I ++KNV+EL V D+D VT
Sbjct: 57 VSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVT 116
Query: 88 GDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSLADRGEWLVSNGVLVAR 147
DD +L+VL+D L + F L+PQG LEVEF L+ E LV+NGVLV+R
Sbjct: 117 PDDHLLTVLYDLTKLCFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSR 176
Query: 148 ELSCLHVQLEETGDQKSSEHRVQLV-VPGSCEG------------PQEASVGTGTFRFHC 194
++SCL V + +K + + LV V S E P A T FH
Sbjct: 177 QVSCLEVHAQSRRRRKREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTAAC-FHY 235
Query: 195 PACWEQELSIRL-----------QDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVEL 243
P ++ ++ + + + + + PL L GQV+ L S E + +
Sbjct: 236 PKYFQSQVHVEVPKSHWSCGLCCRSRKKGPISQPLDCLSDGQVMTLPVGESYE----LHM 291
Query: 244 KKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATG 303
K L VRLGF C E FL +RK VVA AL+Q LQL+ DLQEDE+P++AIMATG
Sbjct: 292 KSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATG 351
Query: 304 GGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLK 363
GG R+MTS+YG L GL++L LLDC SYITG SG+TW +A LY DP+WS K+L +
Sbjct: 352 GGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEAR 411
Query: 364 TQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQR 423
V K+KL L P QL+++++EL +R++ GY FT+ W L+ E L DE ++ KLSDQR
Sbjct: 412 RHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQR 471
Query: 424 EALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMG 483
ALS GQNPLPIY +N K ++ +F EW EFSPYEVG KYGAFIPSELFGSEFFMG
Sbjct: 472 AALSCGQNPLPIYLTINVK-DDVSNQDFREWFEFSPYEVGLQKYGAFIPSELFGSEFFMG 530
Query: 484 QLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKI 543
+L+KR+PESRIC++ G+WS++++ NL D+ + +F+ RW R + D E P+L
Sbjct: 531 RLVKRIPESRICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTREKVQ-DIEDEPIL-- 587
Query: 544 EEPPSTAGRIAE------------FFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFST 591
E P I E F ++LT R HNFL GL H +Y Q+ FS
Sbjct: 588 PEIPKCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQFSR 647
Query: 592 WKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQL 651
WK T LDG PNQLT S HLCLLD + +N+S PLL+P R DLI+ L+Y + L
Sbjct: 648 WKDTVLDGFPNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGSQTKPL 707
Query: 652 QLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAP 711
+ +C Q IPFP P+E +EC+ +P P AP V FPL++D+FR+Y AP
Sbjct: 708 KQTCEYCTVQNIPFPKYE-LPDENENLKECYLMENPQEPDAPIVTFFPLINDTFRKYKAP 766
Query: 712 GVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQA 771
GV R+PEE G+V++ +PY ++TY++ DKL+ L+ YN+ NN++ LL+ALR A
Sbjct: 767 GVERSPEELEQGQVDIYGPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTLLQALRLA 826
Query: 772 VQRRRQ 777
V+++++
Sbjct: 827 VEKKKR 832
>gi|67972429 phospholipase A2, group IVF [Homo sapiens]
Length = 849
Score = 584 bits (1506), Expect = e-167
Identities = 336/803 (41%), Positives = 465/803 (57%), Gaps = 40/803 (4%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 71
L V+VL+A + DL++ +DCYV LWLPTA QTR V N S P WN++FH++IH
Sbjct: 46 LQVKVLRATNIRGTDLLSKADCYVQLWLPTASPSPAQTRIVANCSDPEWNETFHYQIHGA 105
Query: 72 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSL 131
+KNV+EL ++D+D++ G D + +LFD +L+ G+ + +F L+ Q L+VEF L+
Sbjct: 106 VKNVLELTLYDKDIL-GSDQLSLLLFDLRSLKCGQPHKHTFPLNHQDSQELQVEFVLEKS 164
Query: 132 ADRGEWLVSNGVLVARELSCLHVQLEETGD-----QKSSEHRVQLVVPGSCEGPQ----E 182
+++NGVLVA CL +Q GD ++ ++QL VPG+ E PQ +
Sbjct: 165 QVPASEVITNGVLVAHP--CLRIQGTLRGDGTAPREEYGSRQLQLAVPGAYEKPQLLPLQ 222
Query: 183 ASVGTG---TFRFHCPACWEQELSIRL-------QDAPEEQLKAPLSALPSGQVVRLVFP 232
G TF FH L + L Q P +L+A S L G ++ P
Sbjct: 223 PPTEPGLPPTFTFHVNPVLSSRLHVELMELLAAVQSGPSAELEAQTSKLGEGGILLSSLP 282
Query: 233 TSQEPLMRVEL----------KKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQA 282
QE V L K E +L +RLGF EQ FL RRKQVV+ AL+Q
Sbjct: 283 LGQEEQCSVALGEGQEVALSMKVEMSSGDLDLRLGFDLSDGEQEFLDRRKQVVSKALQQV 342
Query: 283 LQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALA 342
L L L ++PVVA++ +GGG RAM+SLYG LAGL+ELGLLD V+Y++G SGSTW ++
Sbjct: 343 LGLSEALDSGQVPVVAVLGSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCIS 402
Query: 343 NLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLW 402
LY DP WSQ L GP E + V +K+G L+ +LQ Y QEL R R G+ +LW
Sbjct: 403 TLYRDPAWSQVALQGPIERAQVHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLW 462
Query: 403 ALINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEV 462
L+ E LL+ E + KLSDQ+EA+ GQNP PIY ++N + +L+ +F EWCEF+PYEV
Sbjct: 463 GLLVEYLLYQEENPAKLSDQQEAVRQGQNPYPIYTSVNVR-TNLSGEDFAEWCEFTPYEV 521
Query: 463 GFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQF 522
GFPKYGA++P+ELFGSE FMG+L++ PE RIC+L+G+W + +A +L + +
Sbjct: 522 GFPKYGAYVPTELFGSELFMGRLLQLQPEPRICYLQGMWGSAFATSLDEIFLKTAGSGLS 581
Query: 523 WDRWVRNQANL-DKEQVPLLKIEEPPST-----AGRIAEFFTDLLTWRPLAQATHNFLRG 576
+ W R N+ D Q P L T G ++ D+ T R + + NF RG
Sbjct: 582 FLEWYRGSVNITDDCQKPQLHNPSRLRTRLLTPQGPFSQAVLDIFTSRFTSAQSFNFTRG 641
Query: 577 LHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDL 636
L HKDY F WK T D PNQLTP L L+D G+ IN+ L P R VDL
Sbjct: 642 LCLHKDYVAGREFVAWKDTHPDAFPNQLTPMRDCLYLVDGGFAINSPFPLALLPQRAVDL 701
Query: 637 ILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVL 696
ILS DY+L F+ L++ ++C ++GIPFP I PE+ + REC+ F+ P +P VL
Sbjct: 702 ILSFDYSLEAPFEVLKMTEKYCLDRGIPFPSIEVGPEDVEEARECYLFAKAEDPRSPIVL 761
Query: 697 HFPLVSDSFREYSAPGV-RRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHY 755
HFPLV+ +FR + APGV R+T EE A G+ ++ D+PY TY +D +L+ L+ Y
Sbjct: 762 HFPLVNRTFRTHLAPGVERQTAEEKAFGDFVINRPDTPYGMMNFTYEPQDFYRLVALSRY 821
Query: 756 NVCNNQEQLLEALRQAVQRRRQR 778
NV NN E L AL+ A+ R + R
Sbjct: 822 NVLNNVETLKCALQLALDRHQAR 844
>gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens]
Length = 749
Score = 241 bits (615), Expect = 2e-63
Identities = 187/656 (28%), Positives = 313/656 (47%), Gaps = 75/656 (11%)
Query: 189 TFRFHCPACWEQELSIRLQDAP---EEQLKAP---LSALPSGQVVRLVFPTSQEPLMRVE 242
TF F E L I L DA +E L +S++ G+ + F +Q M +E
Sbjct: 74 TFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLE 133
Query: 243 LKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQAL---QLDGDLQEDEIPVVAI 299
+ E +R C +E+ F +RK+ + ++++ L +G ++PVVAI
Sbjct: 134 MSLEVCSCP-DLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAI 192
Query: 300 MATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPT 359
+ +GGG RAM G + L E G+LDC +Y+ G SGSTW ++ LY P++ +K
Sbjct: 193 LGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEIN 252
Query: 360 ELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHK 418
E L V+ N L +L P +++RY + L ++ G P FT+++ LI E L+H+ +
Sbjct: 253 EELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNT-T 311
Query: 419 LSDQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGS 478
LS +E ++ Q PLP++ L+ K ++ F +W EFSPYE+G KYG F+ +LFGS
Sbjct: 312 LSSLKEKVNTAQCPLPLFTCLHVK-PDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGS 370
Query: 479 EFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQ----------FWDRWVR 528
+FFMG ++K+ E+ + FL G+W + ++ L + S+ + +
Sbjct: 371 KFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHIV 430
Query: 529 NQANLDKEQVPLLKIEEPPSTAGRIA--EFFTD-------------------LLTWRPLA 567
+ + D + + EP T A ++ +D T A
Sbjct: 431 SNDSSDSDD----ESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRA 486
Query: 568 QATHNFLRGLHFHKDYFQHP--HFSTWKATTLDGL------PNQ-------LTPSEPHLC 612
HNF+ GL+ + Y P F+T + D L P++ L +
Sbjct: 487 GKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIH 546
Query: 613 LLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGA-----FQQLQLLGRFCQEQGIPFPP 667
++D G N +L+P R VDLI+S D++ + F++L L ++ + +PFP
Sbjct: 547 VVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPK 606
Query: 668 ISPSPEEQLQPRECHTFSDPTCP----GAPAVLHFPLVSDSFREYSAPGV-RRTPEEAAA 722
I P ++ +EC+ F P P P ++HF L + +FR+Y APGV R T EE
Sbjct: 607 IDPYVFDREGLKECYVFK-PKNPDMEKDCPTIIHFVLANINFRKYKAPGVPRETEEEKEI 665
Query: 723 GEVNL-SSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQ 777
+ ++ +SP+ Y + +L L H+N NN + + EA+ ++++ RRQ
Sbjct: 666 ADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRRQ 721
Score = 56.2 bits (134), Expect = 1e-07
Identities = 36/124 (29%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Query: 13 TVRVLQAHRLPSK---DLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIH 69
TV VL+A ++ D++ D YV L++ T R +TR N +PVWN++F F +
Sbjct: 21 TVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILD 80
Query: 70 RQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQ 129
+NV+E+ + D + V D+ + + F +++ GE + F + E LE+ +
Sbjct: 81 PNQENVLEITLMDANYVM-DETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLEMSLEVC 139
Query: 130 SLAD 133
S D
Sbjct: 140 SCPD 143
>gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens]
Length = 527
Score = 165 bits (418), Expect = 1e-40
Identities = 153/569 (26%), Positives = 241/569 (42%), Gaps = 124/569 (21%)
Query: 263 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 322
EE+A + RR+ V AL++ ++ DE PVVA++ +GGG+RA + G L+ +KE
Sbjct: 15 EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 69
Query: 323 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 382
GLLD V+Y+ G SGSTWA+++LY + D+ LK + T+ + L +
Sbjct: 70 GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 119
Query: 383 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 441
Q+ + AR S T+ WA ++ + P H LS+ ++ + G P PI+ A++
Sbjct: 120 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 177
Query: 442 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 499
Q S E W EF+P+ GF GAF+ FGS+F G+L++ PE + FL G
Sbjct: 178 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 237
Query: 500 IWSNLYA-------------ANLQDSLYW------------------------------- 515
+W + NL W
Sbjct: 238 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 297
Query: 516 ----ASEPSQFW-----DRWVRNQANLDKEQVPLLKIEEPPSTAGRIAEFF-----TDLL 561
EP W + W R +L+K++ P E P G ++ T +
Sbjct: 298 PEDEGGEPEHTWLTEMLENWTR--TSLEKQEQP----HEDPERKGSLSNLMDFVKKTGIC 351
Query: 562 TWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLIN 621
+ THNFL ++H G+ +++ S HL L+D G IN
Sbjct: 352 ASKWEWGTTHNFL---------YKH-----------GGIRDKIMSSRKHLHLVDAGLAIN 391
Query: 622 TSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPR 679
T +L PTR+V LILS D++ F+ ++ +C+ IPFP + + + P
Sbjct: 392 TPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPA 451
Query: 680 ECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKV 739
C+ T P V+HFPL + +A G++ S
Sbjct: 452 SCYILKGET---GPVVMHFPLFN---------------IDACGGDIEAWSDTYDTFKLAD 493
Query: 740 TYSQEDVDKLLHLTHYNVCNNQEQLLEAL 768
TY+ + V LL L NV N++++L L
Sbjct: 494 TYTLDVVVLLLALAKKNVRENKKKILREL 522
>gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Homo
sapiens]
Length = 551
Score = 165 bits (418), Expect = 1e-40
Identities = 153/569 (26%), Positives = 241/569 (42%), Gaps = 124/569 (21%)
Query: 263 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 322
EE+A + RR+ V AL++ ++ DE PVVA++ +GGG+RA + G L+ +KE
Sbjct: 25 EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 79
Query: 323 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 382
GLLD V+Y+ G SGSTWA+++LY + D+ LK + T+ + L +
Sbjct: 80 GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 129
Query: 383 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 441
Q+ + AR S T+ WA ++ + P H LS+ ++ + G P PI+ A++
Sbjct: 130 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 187
Query: 442 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 499
Q S E W EF+P+ GF GAF+ FGS+F G+L++ PE + FL G
Sbjct: 188 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 247
Query: 500 IWSNLYA-------------ANLQDSLYW------------------------------- 515
+W + NL W
Sbjct: 248 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 307
Query: 516 ----ASEPSQFW-----DRWVRNQANLDKEQVPLLKIEEPPSTAGRIAEFF-----TDLL 561
EP W + W R +L+K++ P E P G ++ T +
Sbjct: 308 PEDEGGEPEHTWLTEMLENWTR--TSLEKQEQP----HEDPERKGSLSNLMDFVKKTGIC 361
Query: 562 TWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLIN 621
+ THNFL ++H G+ +++ S HL L+D G IN
Sbjct: 362 ASKWEWGTTHNFL---------YKH-----------GGIRDKIMSSRKHLHLVDAGLAIN 401
Query: 622 TSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPR 679
T +L PTR+V LILS D++ F+ ++ +C+ IPFP + + + P
Sbjct: 402 TPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPA 461
Query: 680 ECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKV 739
C+ T P V+HFPL + +A G++ S
Sbjct: 462 SCYILKGET---GPVVMHFPLFN---------------IDACGGDIEAWSDTYDTFKLAD 503
Query: 740 TYSQEDVDKLLHLTHYNVCNNQEQLLEAL 768
TY+ + V LL L NV N++++L L
Sbjct: 504 TYTLDVVVLLLALAKKNVRENKKKILREL 532
>gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Homo
sapiens]
Length = 541
Score = 165 bits (418), Expect = 1e-40
Identities = 153/569 (26%), Positives = 241/569 (42%), Gaps = 124/569 (21%)
Query: 263 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 322
EE+A + RR+ V AL++ ++ DE PVVA++ +GGG+RA + G L+ +KE
Sbjct: 15 EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 69
Query: 323 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 382
GLLD V+Y+ G SGSTWA+++LY + D+ LK + T+ + L +
Sbjct: 70 GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 119
Query: 383 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 441
Q+ + AR S T+ WA ++ + P H LS+ ++ + G P PI+ A++
Sbjct: 120 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 177
Query: 442 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 499
Q S E W EF+P+ GF GAF+ FGS+F G+L++ PE + FL G
Sbjct: 178 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 237
Query: 500 IWSNLYA-------------ANLQDSLYW------------------------------- 515
+W + NL W
Sbjct: 238 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 297
Query: 516 ----ASEPSQFW-----DRWVRNQANLDKEQVPLLKIEEPPSTAGRIAEFF-----TDLL 561
EP W + W R +L+K++ P E P G ++ T +
Sbjct: 298 PEDEGGEPEHTWLTEMLENWTR--TSLEKQEQP----HEDPERKGSLSNLMDFVKKTGIC 351
Query: 562 TWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLIN 621
+ THNFL ++H G+ +++ S HL L+D G IN
Sbjct: 352 ASKWEWGTTHNFL---------YKH-----------GGIRDKIMSSRKHLHLVDAGLAIN 391
Query: 622 TSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPR 679
T +L PTR+V LILS D++ F+ ++ +C+ IPFP + + + P
Sbjct: 392 TPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPA 451
Query: 680 ECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKV 739
C+ T P V+HFPL + +A G++ S
Sbjct: 452 SCYILKGET---GPVVMHFPLFN---------------IDACGGDIEAWSDTYDTFKLAD 493
Query: 740 TYSQEDVDKLLHLTHYNVCNNQEQLLEAL 768
TY+ + V LL L NV N++++L L
Sbjct: 494 TYTLDVVVLLLALAKKNVRENKKKILREL 522
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 56.6 bits (135), Expect = 9e-08
Identities = 35/132 (26%), Positives = 65/132 (49%), Gaps = 13/132 (9%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFR---I 68
LTV++++A LP+KD SD +V ++L H+L+T+ + + +P WN++F F
Sbjct: 152 LTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPY 211
Query: 69 HRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRL 128
+ ++ ++ L+V D D + +DP+ V + + + L P +G
Sbjct: 212 EKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGS------- 264
Query: 129 QSLADRGEWLVS 140
RGE L+S
Sbjct: 265 ---GSRGELLLS 273
Score = 38.9 bits (89), Expect = 0.019
Identities = 23/85 (27%), Positives = 47/85 (55%), Gaps = 4/85 (4%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWL--PTACSHRLQTRTVKNSSSPVWNQSFHFRI- 68
+ V +++A L + D+ SD YV +WL + +T T+K + +P++N+SF F I
Sbjct: 283 IIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIP 342
Query: 69 -HRQLKNVMELKVFDQDLVTGDDPV 92
+ + + + V D+D ++ +D +
Sbjct: 343 TEKLRETTIIITVMDKDKLSRNDVI 367
>gi|222352090 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 5 [Homo sapiens]
Length = 947
Score = 53.5 bits (127), Expect = 7e-07
Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Query: 5 EVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHR----LQTRTVKNSSSPVW 60
E + +L V+V+ L KD+ SD YV L L A +R +QT+T+K + +P W
Sbjct: 7 EQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKW 66
Query: 61 NQSFHFRIHRQLKNVMELKVFDQDLVTGDD 90
N+ F+FR++ ++ +VFD++ +T DD
Sbjct: 67 NEEFYFRVNPSNHRLL-FEVFDENRLTRDD 95
>gi|222352088 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 4 [Homo sapiens]
Length = 967
Score = 53.5 bits (127), Expect = 7e-07
Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Query: 5 EVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHR----LQTRTVKNSSSPVW 60
E + +L V+V+ L KD+ SD YV L L A +R +QT+T+K + +P W
Sbjct: 7 EQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKW 66
Query: 61 NQSFHFRIHRQLKNVMELKVFDQDLVTGDD 90
N+ F+FR++ ++ +VFD++ +T DD
Sbjct: 67 NEEFYFRVNPSNHRLL-FEVFDENRLTRDD 95
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 53.5 bits (127), Expect = 7e-07
Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 16/172 (9%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRI-HR 70
L VR+L+A LP+KD SD YV ++L +LQTR + + +P ++++FHF + +
Sbjct: 161 LIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYE 220
Query: 71 QLKN-VMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQ 129
+L + + L VFD D + D + V+ D A + RE+ ++++
Sbjct: 221 ELADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRETSIWK-------DIQYATS 272
Query: 130 SLADRGE------WLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPG 175
D GE +L + G L + C +++ + +V L+ G
Sbjct: 273 ESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDG 324
>gi|21361472 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 3 [Homo sapiens]
Length = 955
Score = 53.1 bits (126), Expect = 9e-07
Identities = 30/84 (35%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
Query: 11 LLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHR----LQTRTVKNSSSPVWNQSFHF 66
+L V+V+ L KD+ SD YV L L A +R +QT+T+K + +P WN+ F+F
Sbjct: 21 ILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF 80
Query: 67 RIHRQLKNVMELKVFDQDLVTGDD 90
R++ ++ +VFD++ +T DD
Sbjct: 81 RVNPSNHRLL-FEVFDENRLTRDD 103
>gi|222352086 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 1 [Homo sapiens]
Length = 975
Score = 53.1 bits (126), Expect = 9e-07
Identities = 30/84 (35%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
Query: 11 LLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHR----LQTRTVKNSSSPVWNQSFHF 66
+L V+V+ L KD+ SD YV L L A +R +QT+T+K + +P WN+ F+F
Sbjct: 21 ILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF 80
Query: 67 RIHRQLKNVMELKVFDQDLVTGDD 90
R++ ++ +VFD++ +T DD
Sbjct: 81 RVNPSNHRLL-FEVFDENRLTRDD 103
>gi|114520609 neural precursor cell expressed, developmentally
down-regulated 4 isoform 1 [Homo sapiens]
Length = 900
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/83 (37%), Positives = 49/83 (59%), Gaps = 4/83 (4%)
Query: 11 LLTVRVLQAHRLPSKDLVTPSDCYV--TLWLP-TACSHRLQTRTVKNSSSPVWNQSFHFR 67
++ VRV+ L KD++ SD YV TL+ P +QT+T+K S +P WN+ FR
Sbjct: 20 IVRVRVIAGIGLAKKDILGASDPYVRVTLYDPMNGVLTSVQTKTIKKSLNPKWNEEILFR 79
Query: 68 IHRQLKNVMELKVFDQDLVTGDD 90
+H Q ++ +VFD++ +T DD
Sbjct: 80 VHPQQHRLL-FEVFDENRLTRDD 101
>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 731
Score = 50.8 bits (120), Expect = 5e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 7 SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHF 66
+R C L VL+A L KD SD +V + +T VK S P WN++F F
Sbjct: 58 ARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK---GRTRETSIVKKSCYPRWNETFEF 114
Query: 67 RIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSP-QGEGRLEVE 125
+ + ++ +D DLV+ +D + V+ D LR + F L P Q + R E
Sbjct: 115 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDE 174
Query: 126 FRLQSL 131
L SL
Sbjct: 175 GNLGSL 180
>gi|239743307 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 1 [Homo sapiens]
Length = 757
Score = 50.8 bits (120), Expect = 5e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 7 SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHF 66
+R C L VL+A L KD SD +V + +T VK S P WN++F F
Sbjct: 130 ARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK---GRTRETSIVKKSCYPRWNETFEF 186
Query: 67 RIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSP-QGEGRLEVE 125
+ + ++ +D DLV+ +D + V+ D LR + F L P Q + R E
Sbjct: 187 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDE 246
Query: 126 FRLQSL 131
L SL
Sbjct: 247 GNLGSL 252
Score = 37.0 bits (84), Expect = 0.070
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 13/146 (8%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 71
L +R+++ LP+KD+ SD Y + + ++T TV + P W + + +
Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDN--EPIIRTATVWKTLCPFWGEEYQVHLPPT 64
Query: 72 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFS-------LSPQGEGRLEV 124
+ + V D+D ++ DD + V T+ + + FS + P E + E+
Sbjct: 65 F-HAVAFYVMDEDALSRDDVIGKVCLTRDTIAS---HPKGFSGWAHLTEVDPDEEVQGEI 120
Query: 125 EFRLQSLADRGEWLVSNGVLVARELS 150
RL+ + VL AR+L+
Sbjct: 121 HLRLEVWPGARACRLRCSVLEARDLA 146
>gi|239508992 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 1 [Homo sapiens]
Length = 731
Score = 50.8 bits (120), Expect = 5e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 7 SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHF 66
+R C L VL+A L KD SD +V + +T VK S P WN++F F
Sbjct: 58 ARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK---GRTRETSIVKKSCYPRWNETFEF 114
Query: 67 RIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSP-QGEGRLEVE 125
+ + ++ +D DLV+ +D + V+ D LR + F L P Q + R E
Sbjct: 115 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDE 174
Query: 126 FRLQSL 131
L SL
Sbjct: 175 GNLGSL 180
>gi|239508990 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 757
Score = 50.8 bits (120), Expect = 5e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 7 SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHF 66
+R C L VL+A L KD SD +V + +T VK S P WN++F F
Sbjct: 130 ARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK---GRTRETSIVKKSCYPRWNETFEF 186
Query: 67 RIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSP-QGEGRLEVE 125
+ + ++ +D DLV+ +D + V+ D LR + F L P Q + R E
Sbjct: 187 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDE 246
Query: 126 FRLQSL 131
L SL
Sbjct: 247 GNLGSL 252
Score = 37.0 bits (84), Expect = 0.070
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 13/146 (8%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 71
L +R+++ LP+KD+ SD Y + + ++T TV + P W + + +
Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDN--EPIIRTATVWKTLCPFWGEEYQVHLPPT 64
Query: 72 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFS-------LSPQGEGRLEV 124
+ + V D+D ++ DD + V T+ + + FS + P E + E+
Sbjct: 65 F-HAVAFYVMDEDALSRDDVIGKVCLTRDTIAS---HPKGFSGWAHLTEVDPDEEVQGEI 120
Query: 125 EFRLQSLADRGEWLVSNGVLVARELS 150
RL+ + VL AR+L+
Sbjct: 121 HLRLEVWPGARACRLRCSVLEARDLA 146
>gi|121114292 RAS p21 protein activator 4 isoform 2 [Homo sapiens]
Length = 757
Score = 50.8 bits (120), Expect = 5e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 7 SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHF 66
+R C L VL+A L KD SD +V + +T VK S P WN++F F
Sbjct: 130 ARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK---GRTRETSIVKKSCYPRWNETFEF 186
Query: 67 RIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSP-QGEGRLEVE 125
+ + ++ +D DLV+ +D + V+ D LR + F L P Q + R E
Sbjct: 187 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDE 246
Query: 126 FRLQSL 131
L SL
Sbjct: 247 GNLGSL 252
Score = 37.0 bits (84), Expect = 0.070
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 13/146 (8%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 71
L +R+++ LP+KD+ SD Y + + ++T TV + P W + + +
Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDN--EPIIRTATVWKTLCPFWGEEYQVHLPPT 64
Query: 72 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFS-------LSPQGEGRLEV 124
+ + V D+D ++ DD + V T+ + + FS + P E + E+
Sbjct: 65 F-HAVAFYVMDEDALSRDDVIGKVCLTRDTIAS---HPKGFSGWAHLTEVDPDEEVQGEI 120
Query: 125 EFRLQSLADRGEWLVSNGVLVARELS 150
RL+ + VL AR+L+
Sbjct: 121 HLRLEVWPGARACRLRCSVLEARDLA 146
>gi|121114294 RAS p21 protein activator 4 isoform 1 [Homo sapiens]
Length = 803
Score = 50.8 bits (120), Expect = 5e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 7 SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHF 66
+R C L VL+A L KD SD +V + +T VK S P WN++F F
Sbjct: 130 ARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK---GRTRETSIVKKSCYPRWNETFEF 186
Query: 67 RIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSP-QGEGRLEVE 125
+ + ++ +D DLV+ +D + V+ D LR + F L P Q + R E
Sbjct: 187 ELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDE 246
Query: 126 FRLQSL 131
L SL
Sbjct: 247 GNLGSL 252
Score = 37.0 bits (84), Expect = 0.070
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 13/146 (8%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 71
L +R+++ LP+KD+ SD Y + + ++T TV + P W + + +
Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDN--EPIIRTATVWKTLCPFWGEEYQVHLPPT 64
Query: 72 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFS-------LSPQGEGRLEV 124
+ + V D+D ++ DD + V T+ + + FS + P E + E+
Sbjct: 65 F-HAVAFYVMDEDALSRDDVIGKVCLTRDTIAS---HPKGFSGWAHLTEVDPDEEVQGEI 120
Query: 125 EFRLQSLADRGEWLVSNGVLVARELS 150
RL+ + VL AR+L+
Sbjct: 121 HLRLEVWPGARACRLRCSVLEARDLA 146
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 50.4 bits (119), Expect = 6e-06
Identities = 38/159 (23%), Positives = 76/159 (47%), Gaps = 18/159 (11%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 71
+++ V+ A L +KD SD YVT+ + + +T+T+ + +PVW ++FHF H
Sbjct: 766 ISITVVCAQGLQAKDKTGSSDPYVTVQVGKT---KKRTKTIYGNLNPVWEENFHFECHNS 822
Query: 72 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSL 131
+ +++V+D+ DD + S + + +F ++ G ++V + L
Sbjct: 823 SDRI-KVRVWDE-----DDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMDVWYNLDKR 876
Query: 132 ADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQ 170
D+ VS + LH+ +E G++K + + VQ
Sbjct: 877 TDKS--AVSGAIR-------LHISVEIKGEEKVAPYHVQ 906
>gi|110611226 UNC13 (C. elegans)-like [Homo sapiens]
Length = 1591
Score = 48.9 bits (115), Expect = 2e-05
Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 18/159 (11%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 71
+T+ V+ A L +KD SD YVT+ + + +T+T+ + +PVW + FHF H
Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQVSKT---KKRTKTIFGNLNPVWEEKFHFECHNS 658
Query: 72 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSL 131
+ +++V+D+ DD + S + + +F ++ G ++V + L+
Sbjct: 659 SDRI-KVRVWDE-----DDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKR 712
Query: 132 ADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQ 170
D+ VS + L + +E G++K + + VQ
Sbjct: 713 TDKS--AVSGAIR-------LQISVEIKGEEKVAPYHVQ 742
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 48.1 bits (113), Expect = 3e-05
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 18/159 (11%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 71
+T+ V+ A L +KD SD YVT+ + ++ +T+T+ + +PVW++ F+F H
Sbjct: 1222 ITITVVSAQGLQAKDKTGSSDPYVTVQVG---KNKRRTKTIFGNLNPVWDEKFYFECHNS 1278
Query: 72 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSL 131
+ +++V+D+ DD + S + + +F ++ G ++V + L+
Sbjct: 1279 TDRI-KVRVWDE-----DDDIKSRVKQHFKKESDDFLGQTIVEVRTLSGEMDVWYNLEKR 1332
Query: 132 ADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQ 170
D+ VS + L + +E G++K + + +Q
Sbjct: 1333 TDKS--AVSGAIR-------LKINVEIKGEEKVAPYHIQ 1362
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 48.1 bits (113), Expect = 3e-05
Identities = 28/90 (31%), Positives = 51/90 (56%), Gaps = 2/90 (2%)
Query: 11 LLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRI-H 69
LL V++++A LP+KD SD YV ++L + QTR + + +P+++++F F + +
Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAY 306
Query: 70 RQLKN-VMELKVFDQDLVTGDDPVLSVLFD 98
QL N + V+D D + D + V+ D
Sbjct: 307 DQLSNRKLHFSVYDFDRFSRHDMIGEVILD 336
Score = 32.3 bits (72), Expect = 1.7
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRL----QTRTVKNSSSPVWNQSFHFR 67
+T+ V++ L + D+ SD YV + L C R +T T KN+ +PV+N++ F
Sbjct: 380 MTLTVIKCRNLKAMDITGSSDPYVKVSL--MCEGRRLKKRKTTTKKNTLNPVYNEAIIFD 437
Query: 68 IHRQLKNVMELK--VFDQDLVTGDDPVLSV 95
I + + + L V D D V G + V+ V
Sbjct: 438 IPPENVDQVSLSIAVMDYDRV-GHNEVIGV 466
>gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Homo
sapiens]
Length = 823
Score = 47.4 bits (111), Expect = 5e-05
Identities = 33/90 (36%), Positives = 51/90 (56%), Gaps = 7/90 (7%)
Query: 2 AVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWN 61
++ +V +L V+VL+A L + D SD + L L + RLQT TV + +P WN
Sbjct: 501 SLKDVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELG---NDRLQTHTVYKNLNPEWN 557
Query: 62 QSFHFRIHRQLKNVMELKVFDQDLVTGDDP 91
+ F F I + + +V+E+ VFD+D GD P
Sbjct: 558 KVFTFPI-KDIHDVLEVTVFDED---GDKP 583
Score = 34.7 bits (78), Expect = 0.35
Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 11 LLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHR 70
LLT+ + + L +D SD YV L ++ ++ + + +PVW++ I +
Sbjct: 195 LLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYK--SKVIYKNLNPVWDEIVVLPI-Q 251
Query: 71 QLKNVMELKVFDQDLVTGD 89
L + +KV+D+DL T D
Sbjct: 252 SLDQKLRVKVYDRDLTTSD 270
>gi|227496440 multiple C2 domains, transmembrane 2 isoform 1 [Homo
sapiens]
Length = 878
Score = 47.4 bits (111), Expect = 5e-05
Identities = 33/90 (36%), Positives = 51/90 (56%), Gaps = 7/90 (7%)
Query: 2 AVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWN 61
++ +V +L V+VL+A L + D SD + L L + RLQT TV + +P WN
Sbjct: 501 SLKDVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELG---NDRLQTHTVYKNLNPEWN 557
Query: 62 QSFHFRIHRQLKNVMELKVFDQDLVTGDDP 91
+ F F I + + +V+E+ VFD+D GD P
Sbjct: 558 KVFTFPI-KDIHDVLEVTVFDED---GDKP 583
Score = 34.7 bits (78), Expect = 0.35
Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 11 LLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHR 70
LLT+ + + L +D SD YV L ++ ++ + + +PVW++ I +
Sbjct: 195 LLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYK--SKVIYKNLNPVWDEIVVLPI-Q 251
Query: 71 QLKNVMELKVFDQDLVTGD 89
L + +KV+D+DL T D
Sbjct: 252 SLDQKLRVKVYDRDLTTSD 270
>gi|227496504 multiple C2 domains, transmembrane 2 isoform 3 [Homo
sapiens]
Length = 306
Score = 47.4 bits (111), Expect = 5e-05
Identities = 33/90 (36%), Positives = 51/90 (56%), Gaps = 7/90 (7%)
Query: 2 AVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWN 61
++ +V +L V+VL+A L + D SD + L L + RLQT TV + +P WN
Sbjct: 89 SLKDVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELG---NDRLQTHTVYKNLNPEWN 145
Query: 62 QSFHFRIHRQLKNVMELKVFDQDLVTGDDP 91
+ F F I + + +V+E+ VFD+D GD P
Sbjct: 146 KVFTFPI-KDIHDVLEVTVFDED---GDKP 171
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 45.4 bits (106), Expect = 2e-04
Identities = 28/89 (31%), Positives = 47/89 (52%), Gaps = 2/89 (2%)
Query: 12 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRI--H 69
L VR+LQA LP+KD SD YV ++L + QT+ + + +PV+N++F F +
Sbjct: 316 LVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPVFNETFQFSVPLA 375
Query: 70 RQLKNVMELKVFDQDLVTGDDPVLSVLFD 98
+ + V+D D + D + V+ D
Sbjct: 376 ELAQRKLHFSVYDFDRFSRHDLIGQVVLD 404
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,634,479
Number of Sequences: 37866
Number of extensions: 1616726
Number of successful extensions: 4207
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 4053
Number of HSP's gapped (non-prelim): 197
length of query: 781
length of database: 18,247,518
effective HSP length: 110
effective length of query: 671
effective length of database: 14,082,258
effective search space: 9449195118
effective search space used: 9449195118
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.