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Search of human proteins with 167614506
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167614506 L-plastin [Homo sapiens]
(627 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167614506 L-plastin [Homo sapiens] 1258 0.0
gi|209862851 plastin 3 [Homo sapiens] 1028 0.0
gi|7549809 plastin 3 [Homo sapiens] 1028 0.0
gi|223718250 plastin 1 [Homo sapiens] 962 0.0
gi|223718246 plastin 1 [Homo sapiens] 962 0.0
gi|221316624 dystonin isoform 4 [Homo sapiens] 76 1e-13
gi|221316622 dystonin isoform 3 [Homo sapiens] 76 1e-13
gi|221316618 dystonin isoform 2 [Homo sapiens] 76 1e-13
gi|34577047 dystonin isoform 1 [Homo sapiens] 76 1e-13
gi|33188445 microfilament and actin filament cross-linker protei... 72 2e-12
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 70 6e-12
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 68 2e-11
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 68 2e-11
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 68 2e-11
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 68 2e-11
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 68 2e-11
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 68 2e-11
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 68 2e-11
gi|67782321 spectrin beta isoform a [Homo sapiens] 66 1e-10
gi|67782319 spectrin beta isoform b [Homo sapiens] 66 1e-10
gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 65 2e-10
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 61 3e-09
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 61 3e-09
gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 60 6e-09
gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens] 60 6e-09
gi|5032283 dystrophin Dp427m isoform [Homo sapiens] 60 6e-09
gi|12025678 actinin, alpha 4 [Homo sapiens] 58 3e-08
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 57 5e-08
gi|110611228 utrophin [Homo sapiens] 57 7e-08
gi|105990514 filamin B, beta (actin binding protein 278) [Homo s... 56 1e-07
>gi|167614506 L-plastin [Homo sapiens]
Length = 627
Score = 1258 bits (3256), Expect = 0.0
Identities = 627/627 (100%), Positives = 627/627 (100%)
Query: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60
MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT
Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60
Query: 61 GDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSE 120
GDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSE
Sbjct: 61 GDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSE 120
Query: 121 EEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTI 180
EEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTI
Sbjct: 121 EEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTI 180
Query: 181 NKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADI 240
NKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADI
Sbjct: 181 NKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADI 240
Query: 241 ELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYY 300
ELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYY
Sbjct: 241 ELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYY 300
Query: 301 HLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP 360
HLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP
Sbjct: 301 HLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP 360
Query: 361 KLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDL 420
KLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDL
Sbjct: 361 KLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDL 420
Query: 421 SDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGG 480
SDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGG
Sbjct: 421 SDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGG 480
Query: 481 QDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISS 540
QDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISS
Sbjct: 481 QDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISS 540
Query: 541 FKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYAL 600
FKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYAL
Sbjct: 541 FKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYAL 600
Query: 601 PEDLVEVNPKMVMTVFACLMGKGMKRV 627
PEDLVEVNPKMVMTVFACLMGKGMKRV
Sbjct: 601 PEDLVEVNPKMVMTVFACLMGKGMKRV 627
>gi|209862851 plastin 3 [Homo sapiens]
Length = 630
Score = 1028 bits (2657), Expect = 0.0
Identities = 501/627 (79%), Positives = 562/627 (89%)
Query: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60
MA +S +E+ EL+EAFAKVD + NG+I EL++LFK A +PLPGY+VREI + LM
Sbjct: 4 MATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLD 63
Query: 61 GDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSE 120
GD ++DG+ISFDEF+ IF +KS+D+AKTFRKAIN+KEGICA+GGTSE SS GTQHSYSE
Sbjct: 64 GDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSE 123
Query: 121 EEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTI 180
EEKYAFVNWINKALENDPDCRHVIPMNPNT+DLF AVGDGIVLCKMINLSVPDTIDER I
Sbjct: 124 EEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAI 183
Query: 181 NKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADI 240
NKKKLTPF IQENLNLALNSASAIGCHVVNIGAEDL+ GKP+LVLGLLWQ+IKIGLFADI
Sbjct: 184 NKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADI 243
Query: 241 ELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYY 300
ELSRNEAL ALLR+GE+LE+LMKLSPEELLLRWAN+HLEN+G KI NFS DIKDSKAY+
Sbjct: 244 ELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYF 303
Query: 301 HLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP 360
HLL Q+APKG +EG P + I+MSG E DD++RAE MLQQA++LGCRQFVT DVV GNP
Sbjct: 304 HLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNP 363
Query: 361 KLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDL 420
KLNLAF+ANLFN+YPAL KPENQDIDW LEGETREERTFRNWMNSLGVNP VNHLY+DL
Sbjct: 364 KLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADL 423
Query: 421 SDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGG 480
DALVI QLYE+IKVPVDW++VNKPPYPKLG NMKKLENCNYAVELGK+ AKFSLVGIGG
Sbjct: 424 QDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGG 483
Query: 481 QDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISS 540
QDLN+GN+TLTLAL+WQLMRRYTLN+LE++G GQK NDDIIVNWVN TL EA KS+SI S
Sbjct: 484 QDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQS 543
Query: 541 FKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYAL 600
FKD IS+SL V+DLIDAIQPG INYDL+K+ NL +D+K NNAKYA+SMAR+IGARVYAL
Sbjct: 544 FKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYAL 603
Query: 601 PEDLVEVNPKMVMTVFACLMGKGMKRV 627
PEDLVEV PKMVMTVFACLMG+GMKRV
Sbjct: 604 PEDLVEVKPKMVMTVFACLMGRGMKRV 630
>gi|7549809 plastin 3 [Homo sapiens]
Length = 630
Score = 1028 bits (2657), Expect = 0.0
Identities = 501/627 (79%), Positives = 562/627 (89%)
Query: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60
MA +S +E+ EL+EAFAKVD + NG+I EL++LFK A +PLPGY+VREI + LM
Sbjct: 4 MATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLD 63
Query: 61 GDLDQDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSE 120
GD ++DG+ISFDEF+ IF +KS+D+AKTFRKAIN+KEGICA+GGTSE SS GTQHSYSE
Sbjct: 64 GDRNKDGKISFDEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSE 123
Query: 121 EEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTI 180
EEKYAFVNWINKALENDPDCRHVIPMNPNT+DLF AVGDGIVLCKMINLSVPDTIDER I
Sbjct: 124 EEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAI 183
Query: 181 NKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADI 240
NKKKLTPF IQENLNLALNSASAIGCHVVNIGAEDL+ GKP+LVLGLLWQ+IKIGLFADI
Sbjct: 184 NKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADI 243
Query: 241 ELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYY 300
ELSRNEAL ALLR+GE+LE+LMKLSPEELLLRWAN+HLEN+G KI NFS DIKDSKAY+
Sbjct: 244 ELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYF 303
Query: 301 HLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP 360
HLL Q+APKG +EG P + I+MSG E DD++RAE MLQQA++LGCRQFVT DVV GNP
Sbjct: 304 HLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNP 363
Query: 361 KLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDL 420
KLNLAF+ANLFN+YPAL KPENQDIDW LEGETREERTFRNWMNSLGVNP VNHLY+DL
Sbjct: 364 KLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYADL 423
Query: 421 SDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGG 480
DALVI QLYE+IKVPVDW++VNKPPYPKLG NMKKLENCNYAVELGK+ AKFSLVGIGG
Sbjct: 424 QDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKHPAKFSLVGIGG 483
Query: 481 QDLNEGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISS 540
QDLN+GN+TLTLAL+WQLMRRYTLN+LE++G GQK NDDIIVNWVN TL EA KS+SI S
Sbjct: 484 QDLNDGNQTLTLALVWQLMRRYTLNVLEDLGDGQKANDDIIVNWVNRTLSEAGKSTSIQS 543
Query: 541 FKDPKISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYAL 600
FKD IS+SL V+DLIDAIQPG INYDL+K+ NL +D+K NNAKYA+SMAR+IGARVYAL
Sbjct: 544 FKDKTISSSLAVVDLIDAIQPGCINYDLVKSGNLTEDDKHNNAKYAVSMARRIGARVYAL 603
Query: 601 PEDLVEVNPKMVMTVFACLMGKGMKRV 627
PEDLVEV PKMVMTVFACLMG+GMKRV
Sbjct: 604 PEDLVEVKPKMVMTVFACLMGRGMKRV 630
>gi|223718250 plastin 1 [Homo sapiens]
Length = 629
Score = 962 bits (2487), Expect = 0.0
Identities = 461/623 (73%), Positives = 541/623 (86%), Gaps = 1/623 (0%)
Query: 5 SVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLD 64
++S EE+ EL+EAF K+D D +GY+S EL DLFK A LPLPGY+VREI E +++ D +
Sbjct: 7 TISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILSVADSN 66
Query: 65 QDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKY 124
+DG+ISF+EF+ + LKS D++KTFRK INK+EGI AIGGTS SS GTQHSYSEEEK
Sbjct: 67 KDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSTISSEGTQHSYSEEEKV 126
Query: 125 AFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINKKK 184
AFVNWINKALENDPDC+H+IPMNPN + LF ++ DGI+LCKMINLS PDTIDER INKKK
Sbjct: 127 AFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERAINKKK 186
Query: 185 LTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSR 244
LTPFTI ENLNLALNSASAIGC VVNIGA DLKEGKP+LVLGLLWQ+IK+GLFADIE+SR
Sbjct: 187 LTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFADIEISR 246
Query: 245 NEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLE 304
NEALIALL EGE LE+LMKLSPEELLLRW NYHL NAG + I NFS DIKDS+AY+HLL
Sbjct: 247 NEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWHTISNFSQDIKDSRAYFHLLN 306
Query: 305 QVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNL 364
Q+APKG E+G PA+ ID+SG+ E +D++RA MLQ+A++LGC+QFVT DVV GNPKLNL
Sbjct: 307 QIAPKGGEDG-PAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNPKLNL 365
Query: 365 AFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDAL 424
AF+ANLFN YP LHKP N DID LEGE++EERTFRNWMNSLGVNP +NHLYSDL+DAL
Sbjct: 366 AFVANLFNTYPCLHKPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADAL 425
Query: 425 VIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLN 484
VIFQLYE I+VPV+W+ VNKPPYP LGGNMKK+ENCNYAVELGKN+AKFSLVGI GQDLN
Sbjct: 426 VIFQLYEMIRVPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLN 485
Query: 485 EGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDP 544
EGN TLTLAL+WQLMRRYTLN+L ++G G+KVND+II+ WVN+TL+ A K +SISSFKD
Sbjct: 486 EGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLKSANKKTSISSFKDK 545
Query: 545 KISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDL 604
ISTSLPVLDLIDAI P ++ ++++ ENL+D++KLNNAKYAIS+ARKIGAR+YALP+DL
Sbjct: 546 SISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDL 605
Query: 605 VEVNPKMVMTVFACLMGKGMKRV 627
VEV PKMVMTVFACLMGKG+ R+
Sbjct: 606 VEVKPKMVMTVFACLMGKGLNRI 628
>gi|223718246 plastin 1 [Homo sapiens]
Length = 629
Score = 962 bits (2487), Expect = 0.0
Identities = 461/623 (73%), Positives = 541/623 (86%), Gaps = 1/623 (0%)
Query: 5 SVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLD 64
++S EE+ EL+EAF K+D D +GY+S EL DLFK A LPLPGY+VREI E +++ D +
Sbjct: 7 TISREELEELQEAFNKIDIDNSGYVSDYELQDLFKEASLPLPGYKVREIVEKILSVADSN 66
Query: 65 QDGRISFDEFIKIFHGLKSTDVAKTFRKAINKKEGICAIGGTSEQSSVGTQHSYSEEEKY 124
+DG+ISF+EF+ + LKS D++KTFRK INK+EGI AIGGTS SS GTQHSYSEEEK
Sbjct: 67 KDGKISFEEFVSLMQELKSKDISKTFRKIINKREGITAIGGTSTISSEGTQHSYSEEEKV 126
Query: 125 AFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTINKKK 184
AFVNWINKALENDPDC+H+IPMNPN + LF ++ DGI+LCKMINLS PDTIDER INKKK
Sbjct: 127 AFVNWINKALENDPDCKHLIPMNPNDDSLFKSLADGILLCKMINLSEPDTIDERAINKKK 186
Query: 185 LTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIELSR 244
LTPFTI ENLNLALNSASAIGC VVNIGA DLKEGKP+LVLGLLWQ+IK+GLFADIE+SR
Sbjct: 187 LTPFTISENLNLALNSASAIGCTVVNIGASDLKEGKPHLVLGLLWQIIKVGLFADIEISR 246
Query: 245 NEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLE 304
NEALIALL EGE LE+LMKLSPEELLLRW NYHL NAG + I NFS DIKDS+AY+HLL
Sbjct: 247 NEALIALLNEGEELEELMKLSPEELLLRWVNYHLTNAGWHTISNFSQDIKDSRAYFHLLN 306
Query: 305 QVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNL 364
Q+APKG E+G PA+ ID+SG+ E +D++RA MLQ+A++LGC+QFVT DVV GNPKLNL
Sbjct: 307 QIAPKGGEDG-PAIAIDLSGINETNDLKRAGLMLQEADKLGCKQFVTPADVVSGNPKLNL 365
Query: 365 AFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPRVNHLYSDLSDAL 424
AF+ANLFN YP LHKP N DID LEGE++EERTFRNWMNSLGVNP +NHLYSDL+DAL
Sbjct: 366 AFVANLFNTYPCLHKPNNNDIDMNLLEGESKEERTFRNWMNSLGVNPYINHLYSDLADAL 425
Query: 425 VIFQLYEKIKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLN 484
VIFQLYE I+VPV+W+ VNKPPYP LGGNMKK+ENCNYAVELGKN+AKFSLVGI GQDLN
Sbjct: 426 VIFQLYEMIRVPVNWSHVNKPPYPALGGNMKKIENCNYAVELGKNKAKFSLVGIAGQDLN 485
Query: 485 EGNRTLTLALIWQLMRRYTLNILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDP 544
EGN TLTLAL+WQLMRRYTLN+L ++G G+KVND+II+ WVN+TL+ A K +SISSFKD
Sbjct: 486 EGNSTLTLALVWQLMRRYTLNVLSDLGEGEKVNDEIIIKWVNQTLKSANKKTSISSFKDK 545
Query: 545 KISTSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDL 604
ISTSLPVLDLIDAI P ++ ++++ ENL+D++KLNNAKYAIS+ARKIGAR+YALP+DL
Sbjct: 546 SISTSLPVLDLIDAIAPNAVRQEMIRRENLSDEDKLNNAKYAISVARKIGARIYALPDDL 605
Query: 605 VEVNPKMVMTVFACLMGKGMKRV 627
VEV PKMVMTVFACLMGKG+ R+
Sbjct: 606 VEVKPKMVMTVFACLMGKGLNRI 628
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 75.9 bits (185), Expect = 1e-13
Identities = 63/256 (24%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F WIN+ H++ + + NDL+ + DG L ++ + DT+
Sbjct: 66 QKKTFTKWINQ---------HLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR---- 112
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI
Sbjct: 113 EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 172
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
++ GES ED +S +E LL W E + NF+T +D K +
Sbjct: 173 VT-----------GES-ED---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA 217
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP- 360
++ + P +IDM+ + + ++ E AE++G + + DV +P
Sbjct: 218 IIHKYRPD---------LIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPD 268
Query: 361 -KLNLAFIANLFNRYP 375
K + ++++L++ +P
Sbjct: 269 EKSVITYVSSLYDAFP 284
Score = 58.2 bits (139), Expect = 2e-08
Identities = 58/239 (24%), Positives = 107/239 (44%), Gaps = 30/239 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + V VN LY DL D + L E + + P
Sbjct: 61 ERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVL---------SGDTLP 111
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ +L+N A++ K + + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 112 REKGRMRFHRLQNVQIALDYLKRR-QVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISD 170
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
+ G + ++ + ++ W E + + + ++D K+ + +I +P
Sbjct: 171 IHVTGESEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA-----IIHKYRP- 224
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNP--KMVMTVFACL 619
DL+ + L N ++A +A KIG PED+ +P K V+T + L
Sbjct: 225 ----DLIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSL 279
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 75.9 bits (185), Expect = 1e-13
Identities = 63/256 (24%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F WIN+ H++ + + NDL+ + DG L ++ + DT+
Sbjct: 77 QKKTFTKWINQ---------HLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR---- 123
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI
Sbjct: 124 EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 183
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
++ GES ED +S +E LL W E + NF+T +D K +
Sbjct: 184 VT-----------GES-ED---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA 228
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP- 360
++ + P +IDM+ + + ++ E AE++G + + DV +P
Sbjct: 229 IIHKYRPD---------LIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPD 279
Query: 361 -KLNLAFIANLFNRYP 375
K + ++++L++ +P
Sbjct: 280 EKSVITYVSSLYDAFP 295
Score = 58.2 bits (139), Expect = 2e-08
Identities = 58/239 (24%), Positives = 107/239 (44%), Gaps = 30/239 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + V VN LY DL D + L E + + P
Sbjct: 72 ERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVL---------SGDTLP 122
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ +L+N A++ K + + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 123 REKGRMRFHRLQNVQIALDYLKRR-QVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISD 181
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
+ G + ++ + ++ W E + + + ++D K+ + +I +P
Sbjct: 182 IHVTGESEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA-----IIHKYRP- 235
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNP--KMVMTVFACL 619
DL+ + L N ++A +A KIG PED+ +P K V+T + L
Sbjct: 236 ----DLIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSL 290
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 75.9 bits (185), Expect = 1e-13
Identities = 63/256 (24%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F WIN+ H++ + + NDL+ + DG L ++ + DT+
Sbjct: 215 QKKTFTKWINQ---------HLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR---- 261
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI
Sbjct: 262 EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 321
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
++ GES ED +S +E LL W E + NF+T +D K +
Sbjct: 322 VT-----------GES-ED---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA 366
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP- 360
++ + P +IDM+ + + ++ E AE++G + + DV +P
Sbjct: 367 IIHKYRPD---------LIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPD 417
Query: 361 -KLNLAFIANLFNRYP 375
K + ++++L++ +P
Sbjct: 418 EKSVITYVSSLYDAFP 433
Score = 58.2 bits (139), Expect = 2e-08
Identities = 58/239 (24%), Positives = 107/239 (44%), Gaps = 30/239 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + V VN LY DL D + L E + + P
Sbjct: 210 ERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVL---------SGDTLP 260
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ +L+N A++ K + + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 261 REKGRMRFHRLQNVQIALDYLKRR-QVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISD 319
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
+ G + ++ + ++ W E + + + ++D K+ + +I +P
Sbjct: 320 IHVTGESEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA-----IIHKYRP- 373
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNP--KMVMTVFACL 619
DL+ + L N ++A +A KIG PED+ +P K V+T + L
Sbjct: 374 ----DLIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSL 428
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 75.9 bits (185), Expect = 1e-13
Identities = 63/256 (24%), Positives = 117/256 (45%), Gaps = 39/256 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F WIN+ H++ + + NDL+ + DG L ++ + DT+
Sbjct: 37 QKKTFTKWINQ---------HLMKVRKHVNDLYEDLRDGHNLISLLEVLSGDTLPR---- 83
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI
Sbjct: 84 EKGRMRFHRLQNVQIALDYLKRRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISDIH 143
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
++ GES ED +S +E LL W E + NF+T +D K +
Sbjct: 144 VT-----------GES-ED---MSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA 188
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNP- 360
++ + P +IDM+ + + ++ E AE++G + + DV +P
Sbjct: 189 IIHKYRPD---------LIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPD 239
Query: 361 -KLNLAFIANLFNRYP 375
K + ++++L++ +P
Sbjct: 240 EKSVITYVSSLYDAFP 255
Score = 58.2 bits (139), Expect = 2e-08
Identities = 58/239 (24%), Positives = 107/239 (44%), Gaps = 30/239 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + V VN LY DL D + L E + + P
Sbjct: 32 ERDKVQKKTFTKWINQHLMKVRKHVNDLYEDLRDGHNLISLLEVL---------SGDTLP 82
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ +L+N A++ K + + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 83 REKGRMRFHRLQNVQIALDYLKRR-QVKLVNIRNDDITDGNPKLTLGLIWTIILHFQISD 141
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
+ G + ++ + ++ W E + + + ++D K+ + +I +P
Sbjct: 142 IHVTGESEDMSAKERLLLWTQQATEGYAGIRCENFTTCWRDGKLFNA-----IIHKYRP- 195
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNP--KMVMTVFACL 619
DL+ + L N ++A +A KIG PED+ +P K V+T + L
Sbjct: 196 ----DLIDMNTVAVQSNLANLEHAFYVAEKIGVIRLLDPEDVDVSSPDEKSVITYVSSL 250
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 71.6 bits (174), Expect = 2e-12
Identities = 64/271 (23%), Positives = 119/271 (43%), Gaps = 39/271 (14%)
Query: 107 SEQSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKM 166
+E++ V +K F W+NK H++ + + NDL+ + DG L +
Sbjct: 65 AERAVVRVADERDRVQKKTFTKWVNK---------HLMKVRKHINDLYEDLRDGHNLISL 115
Query: 167 INLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLG 226
+ + + +K F +N+ +AL+ +VNI +D+ +G P L LG
Sbjct: 116 LEVLSGIKLPR----EKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDDITDGNPKLTLG 171
Query: 227 LLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKI 286
L+W +I +DI +S GES + +S +E LL W K
Sbjct: 172 LIWTIILHFQISDIYIS-----------GESGD----MSAKEKLLLWTQKVTAGYTGIKC 216
Query: 287 GNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGC 346
NFS+ D K + L+ + P ++DM ++ + + + E + AERLG
Sbjct: 217 TNFSSCWSDGKMFNALIHRYRPD---------LVDMERVQIQSNRENLEQAFEVAERLGV 267
Query: 347 RQFVTATDVVRGNP--KLNLAFIANLFNRYP 375
+ + A DV +P K + +++++++ +P
Sbjct: 268 TRLLDAEDVDVPSPDEKSVITYVSSIYDAFP 298
Score = 54.7 bits (130), Expect = 3e-07
Identities = 59/235 (25%), Positives = 101/235 (42%), Gaps = 32/235 (13%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEK---IKVPVDWNRVNKP 445
E + +++TF W+N + V +N LY DL D + L E IK+P + R+
Sbjct: 75 ERDRVQKKTFTKWVNKHLMKVRKHINDLYEDLRDGHNLISLLEVLSGIKLPREKGRMR-- 132
Query: 446 PYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLN 505
+L+N A++ K Q + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 133 --------FHRLQNVQIALDFLK-QRQVKLVNIRNDDITDGNPKLTLGLIWTIILHFQIS 183
Query: 506 ILEEIG-GGQKVNDDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQP 561
+ G G + ++ W V K ++ S + D K+ + LI +P
Sbjct: 184 DIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTNFSSCWSDGKMFNA-----LIHRYRP 238
Query: 562 GSINYDLLKTENLNDDEKLNNAKYAISMARKIGARVYALPEDLVEVNP--KMVMT 614
DL+ E + N + A +A ++G ED+ +P K V+T
Sbjct: 239 -----DLVDMERVQIQSNRENLEQAFEVAERLGVTRLLDAEDVDVPSPDEKSVIT 288
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 70.1 bits (170), Expect = 6e-12
Identities = 65/279 (23%), Positives = 129/279 (46%), Gaps = 42/279 (15%)
Query: 109 QSSVGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMIN 168
++S G + +K F W+NK H+I + +DL+ + DG L ++
Sbjct: 31 RASEGKKDERDRVQKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLE 81
Query: 169 LSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLL 228
+ D++ +K F +N+ +AL+ +VNI +D+ +G P L LGL+
Sbjct: 82 VLSGDSLPR----EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLI 137
Query: 229 WQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGN 288
W +I +DI++S G+S ED ++ +E LL W+ +E + N
Sbjct: 138 WTIILHFQISDIQVS-----------GQS-ED---MTAKEKLLLWSQRMVEGYQGLRCDN 182
Query: 289 FSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCR 347
F++ +D + + ++ + P ++IDM+ + + +++ + AER LG
Sbjct: 183 FTSSWRDGRLFNAIIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVT 233
Query: 348 QFVTATDVVRGNP--KLNLAFIANLFNRYPALHKPENQD 384
+ + DV P K + ++++L++ P + P+ QD
Sbjct: 234 RLLDPEDVDVPQPDEKSIITYVSSLYDAMPRV--PDVQD 270
Score = 46.6 bits (109), Expect = 7e-05
Identities = 54/240 (22%), Positives = 109/240 (45%), Gaps = 31/240 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + ++ LY DL D + L E + + P
Sbjct: 39 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL---------SGDSLP 89
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ KL+N A++ +++ + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 90 REKGRMRFHKLQNVQIALDYLRHR-QVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 148
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
++ G + + + ++ W + E + + + SS++D ++ + +I +P
Sbjct: 149 IQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA-----IIHRHKPL 203
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP--KMVMTVFACL 619
I+ + + + L N A S+A R +G PED+ P K ++T + L
Sbjct: 204 LIDMNKVYRQT-----NLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSL 258
Score = 29.6 bits (65), Expect = 8.7
Identities = 30/126 (23%), Positives = 48/126 (38%), Gaps = 10/126 (7%)
Query: 243 SRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHL 302
S + +A+LR E +D ++ +W N HL A I + D++D L
Sbjct: 21 SEDNLYLAVLRASEGKKDERDRVQKKTFTKWVNKHLIKAQ-RHISDLYEDLRDGHNLISL 79
Query: 303 LEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAERLGCRQF-VTATDVVRGNPK 361
LE ++ GD + G +Q + L + + D+ GNPK
Sbjct: 80 LEVLS--GDS------LPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPK 131
Query: 362 LNLAFI 367
L L I
Sbjct: 132 LTLGLI 137
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/266 (23%), Positives = 124/266 (46%), Gaps = 42/266 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+NK H+I + +DL+ + DG L ++ + D++
Sbjct: 48 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 94
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI+
Sbjct: 95 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 154
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+S G+S ED ++ +E LL W+ +E + NF++ +D + +
Sbjct: 155 VS-----------GQS-ED---MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 199
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
++ + P ++IDM+ + + +++ + AER LG + + DV P
Sbjct: 200 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 250
Query: 361 --KLNLAFIANLFNRYPALHKPENQD 384
K + ++++L++ P + P+ QD
Sbjct: 251 DEKSIITYVSSLYDAMPRV--PDVQD 274
Score = 46.6 bits (109), Expect = 7e-05
Identities = 54/240 (22%), Positives = 109/240 (45%), Gaps = 31/240 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + ++ LY DL D + L E + + P
Sbjct: 43 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL---------SGDSLP 93
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ KL+N A++ +++ + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 94 REKGRMRFHKLQNVQIALDYLRHR-QVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 152
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
++ G + + + ++ W + E + + + SS++D ++ + +I +P
Sbjct: 153 IQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA-----IIHRHKPL 207
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP--KMVMTVFACL 619
I+ + + + L N A S+A R +G PED+ P K ++T + L
Sbjct: 208 LIDMNKVYRQT-----NLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSL 262
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/266 (23%), Positives = 124/266 (46%), Gaps = 42/266 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+NK H+I + +DL+ + DG L ++ + D++
Sbjct: 44 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 90
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI+
Sbjct: 91 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 150
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+S G+S ED ++ +E LL W+ +E + NF++ +D + +
Sbjct: 151 VS-----------GQS-ED---MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 195
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
++ + P ++IDM+ + + +++ + AER LG + + DV P
Sbjct: 196 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 246
Query: 361 --KLNLAFIANLFNRYPALHKPENQD 384
K + ++++L++ P + P+ QD
Sbjct: 247 DEKSIITYVSSLYDAMPRV--PDVQD 270
Score = 46.6 bits (109), Expect = 7e-05
Identities = 54/240 (22%), Positives = 109/240 (45%), Gaps = 31/240 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + ++ LY DL D + L E + + P
Sbjct: 39 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL---------SGDSLP 89
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ KL+N A++ +++ + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 90 REKGRMRFHKLQNVQIALDYLRHR-QVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 148
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
++ G + + + ++ W + E + + + SS++D ++ + +I +P
Sbjct: 149 IQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA-----IIHRHKPL 203
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP--KMVMTVFACL 619
I+ + + + L N A S+A R +G PED+ P K ++T + L
Sbjct: 204 LIDMNKVYRQT-----NLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSL 258
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/266 (23%), Positives = 124/266 (46%), Gaps = 42/266 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+NK H+I + +DL+ + DG L ++ + D++
Sbjct: 12 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 58
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI+
Sbjct: 59 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 118
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+S G+S ED ++ +E LL W+ +E + NF++ +D + +
Sbjct: 119 VS-----------GQS-ED---MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 163
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
++ + P ++IDM+ + + +++ + AER LG + + DV P
Sbjct: 164 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 214
Query: 361 --KLNLAFIANLFNRYPALHKPENQD 384
K + ++++L++ P + P+ QD
Sbjct: 215 DEKSIITYVSSLYDAMPRV--PDVQD 238
Score = 46.6 bits (109), Expect = 7e-05
Identities = 54/240 (22%), Positives = 109/240 (45%), Gaps = 31/240 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + ++ LY DL D + L E + + P
Sbjct: 7 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL---------SGDSLP 57
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ KL+N A++ +++ + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 58 REKGRMRFHKLQNVQIALDYLRHR-QVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 116
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
++ G + + + ++ W + E + + + SS++D ++ + +I +P
Sbjct: 117 IQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA-----IIHRHKPL 171
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP--KMVMTVFACL 619
I+ + + + L N A S+A R +G PED+ P K ++T + L
Sbjct: 172 LIDMNKVYRQT-----NLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSL 226
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/266 (23%), Positives = 124/266 (46%), Gaps = 42/266 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+NK H+I + +DL+ + DG L ++ + D++
Sbjct: 181 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 227
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI+
Sbjct: 228 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 287
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+S G+S ED ++ +E LL W+ +E + NF++ +D + +
Sbjct: 288 VS-----------GQS-ED---MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 332
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
++ + P ++IDM+ + + +++ + AER LG + + DV P
Sbjct: 333 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 383
Query: 361 --KLNLAFIANLFNRYPALHKPENQD 384
K + ++++L++ P + P+ QD
Sbjct: 384 DEKSIITYVSSLYDAMPRV--PDVQD 407
Score = 46.6 bits (109), Expect = 7e-05
Identities = 54/240 (22%), Positives = 109/240 (45%), Gaps = 31/240 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + ++ LY DL D + L E + + P
Sbjct: 176 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL---------SGDSLP 226
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ KL+N A++ +++ + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 227 REKGRMRFHKLQNVQIALDYLRHR-QVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 285
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
++ G + + + ++ W + E + + + SS++D ++ + +I +P
Sbjct: 286 IQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA-----IIHRHKPL 340
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP--KMVMTVFACL 619
I+ + + + L N A S+A R +G PED+ P K ++T + L
Sbjct: 341 LIDMNKVYRQT-----NLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSL 395
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/266 (23%), Positives = 124/266 (46%), Gaps = 42/266 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+NK H+I + +DL+ + DG L ++ + D++
Sbjct: 22 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 68
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI+
Sbjct: 69 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 128
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+S G+S ED ++ +E LL W+ +E + NF++ +D + +
Sbjct: 129 VS-----------GQS-ED---MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 173
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
++ + P ++IDM+ + + +++ + AER LG + + DV P
Sbjct: 174 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 224
Query: 361 --KLNLAFIANLFNRYPALHKPENQD 384
K + ++++L++ P + P+ QD
Sbjct: 225 DEKSIITYVSSLYDAMPRV--PDVQD 248
Score = 46.6 bits (109), Expect = 7e-05
Identities = 54/240 (22%), Positives = 109/240 (45%), Gaps = 31/240 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + ++ LY DL D + L E + + P
Sbjct: 17 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL---------SGDSLP 67
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ KL+N A++ +++ + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 68 REKGRMRFHKLQNVQIALDYLRHR-QVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 126
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
++ G + + + ++ W + E + + + SS++D ++ + +I +P
Sbjct: 127 IQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA-----IIHRHKPL 181
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP--KMVMTVFACL 619
I+ + + + L N A S+A R +G PED+ P K ++T + L
Sbjct: 182 LIDMNKVYRQT-----NLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSL 236
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/266 (23%), Positives = 124/266 (46%), Gaps = 42/266 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+NK H+I + +DL+ + DG L ++ + D++
Sbjct: 30 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 76
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI+
Sbjct: 77 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 136
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+S G+S ED ++ +E LL W+ +E + NF++ +D + +
Sbjct: 137 VS-----------GQS-ED---MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 181
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
++ + P ++IDM+ + + +++ + AER LG + + DV P
Sbjct: 182 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 232
Query: 361 --KLNLAFIANLFNRYPALHKPENQD 384
K + ++++L++ P + P+ QD
Sbjct: 233 DEKSIITYVSSLYDAMPRV--PDVQD 256
Score = 46.6 bits (109), Expect = 7e-05
Identities = 54/240 (22%), Positives = 109/240 (45%), Gaps = 31/240 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + ++ LY DL D + L E + + P
Sbjct: 25 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL---------SGDSLP 75
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ KL+N A++ +++ + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 76 REKGRMRFHKLQNVQIALDYLRHR-QVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 134
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
++ G + + + ++ W + E + + + SS++D ++ + +I +P
Sbjct: 135 IQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA-----IIHRHKPL 189
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP--KMVMTVFACL 619
I+ + + + L N A S+A R +G PED+ P K ++T + L
Sbjct: 190 LIDMNKVYRQT-----NLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSL 244
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 68.2 bits (165), Expect = 2e-11
Identities = 63/266 (23%), Positives = 124/266 (46%), Gaps = 42/266 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+NK H+I + +DL+ + DG L ++ + D++
Sbjct: 71 QKKTFTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 117
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI+
Sbjct: 118 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 177
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+S G+S ED ++ +E LL W+ +E + NF++ +D + +
Sbjct: 178 VS-----------GQS-ED---MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 222
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
++ + P ++IDM+ + + +++ + AER LG + + DV P
Sbjct: 223 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 273
Query: 361 --KLNLAFIANLFNRYPALHKPENQD 384
K + ++++L++ P + P+ QD
Sbjct: 274 DEKSIITYVSSLYDAMPRV--PDVQD 297
Score = 46.6 bits (109), Expect = 7e-05
Identities = 54/240 (22%), Positives = 109/240 (45%), Gaps = 31/240 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++TF W+N + ++ LY DL D + L E + + P
Sbjct: 66 ERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL---------SGDSLP 116
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ KL+N A++ +++ + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 117 REKGRMRFHKLQNVQIALDYLRHR-QVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 175
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
++ G + + + ++ W + E + + + SS++D ++ + +I +P
Sbjct: 176 IQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA-----IIHRHKPL 230
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP--KMVMTVFACL 619
I+ + + + L N A S+A R +G PED+ P K ++T + L
Sbjct: 231 LIDMNKVYRQT-----NLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSL 285
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 65.9 bits (159), Expect = 1e-10
Identities = 63/228 (27%), Positives = 109/228 (47%), Gaps = 26/228 (11%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E E +++TF W+NS V+ R+ LY DL D ++ +L E + + + KP
Sbjct: 51 EREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEM----LPKPTKG 106
Query: 449 KLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTL-NIL 507
K+ + LEN + A++ K Q + L +G D+ +GN L L LIW ++ R+ + +I+
Sbjct: 107 KM--RIHCLENVDKALQFLKEQ-RVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
Query: 508 EEIGGGQKVND--DIIVNWVNETLR---EAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
+ G++ D ++ W ++ SS+KD L LI +P
Sbjct: 164 VQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKD-----GLAFNALIHKHRPD 218
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP 609
I++D LK N +N ++A ++A R++G PED+ NP
Sbjct: 219 LIDFDKLKDSNAR-----HNLEHAFNVAERQLGIIPLLDPEDVFTENP 261
Score = 62.4 bits (150), Expect = 1e-09
Identities = 59/240 (24%), Positives = 97/240 (40%), Gaps = 35/240 (14%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+N H+ ++ DL+ + DG +L K++ + + + + T
Sbjct: 56 QKKTFTKWVNS---------HLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKG 106
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
K ++ EN++ AL H+ N+G+ D+ +G LVLGL+W +I DI
Sbjct: 107 KMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+ E RE S +D LL W + NF++ KD A+
Sbjct: 164 VQTQEG-----RETRSAKD--------ALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNA 210
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
L+ + P +ID L++ + E AER LG + DV NP
Sbjct: 211 LIHKHRPD---------LIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENP 261
Score = 32.3 bits (72), Expect = 1.3
Identities = 42/188 (22%), Positives = 79/188 (42%), Gaps = 22/188 (11%)
Query: 214 EDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREG--ESLEDLMKLSPEELLL 271
E++ PY + W D EL + + L ++L D ++ ++
Sbjct: 8 ENVGNQPPYSRINARWDA------PDDELDNDNSSARLFERSRIKALADEREVVQKKTFT 61
Query: 272 RWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDI 331
+W N HL C +I + D++D + LLE ++ E +P + +++
Sbjct: 62 KWVNSHLARVSC-RITDLYKDLRDGRMLIKLLEVLS----GEMLPKPTKGKMRIHCLENV 116
Query: 332 QRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALHKPENQDIDWGALE 391
+A L++ +R+ + + D+V GN +L L I + R+ + QDI E
Sbjct: 117 DKALQFLKE-QRVHLEN-MGSHDIVDGNHRLVLGLIWTIILRF------QIQDIVVQTQE 168
Query: 392 G-ETREER 398
G ETR +
Sbjct: 169 GRETRSAK 176
>gi|67782319 spectrin beta isoform b [Homo sapiens]
Length = 2137
Score = 65.9 bits (159), Expect = 1e-10
Identities = 63/228 (27%), Positives = 109/228 (47%), Gaps = 26/228 (11%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E E +++TF W+NS V+ R+ LY DL D ++ +L E + + + KP
Sbjct: 51 EREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEM----LPKPTKG 106
Query: 449 KLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTL-NIL 507
K+ + LEN + A++ K Q + L +G D+ +GN L L LIW ++ R+ + +I+
Sbjct: 107 KM--RIHCLENVDKALQFLKEQ-RVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
Query: 508 EEIGGGQKVND--DIIVNWVNETLR---EAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
+ G++ D ++ W ++ SS+KD L LI +P
Sbjct: 164 VQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKD-----GLAFNALIHKHRPD 218
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP 609
I++D LK N +N ++A ++A R++G PED+ NP
Sbjct: 219 LIDFDKLKDSNAR-----HNLEHAFNVAERQLGIIPLLDPEDVFTENP 261
Score = 62.4 bits (150), Expect = 1e-09
Identities = 59/240 (24%), Positives = 97/240 (40%), Gaps = 35/240 (14%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+N H+ ++ DL+ + DG +L K++ + + + + T
Sbjct: 56 QKKTFTKWVNS---------HLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKG 106
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
K ++ EN++ AL H+ N+G+ D+ +G LVLGL+W +I DI
Sbjct: 107 KMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIV 163
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+ E RE S +D LL W + NF++ KD A+
Sbjct: 164 VQTQEG-----RETRSAKD--------ALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNA 210
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
L+ + P +ID L++ + E AER LG + DV NP
Sbjct: 211 LIHKHRPD---------LIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENP 261
Score = 32.3 bits (72), Expect = 1.3
Identities = 42/188 (22%), Positives = 79/188 (42%), Gaps = 22/188 (11%)
Query: 214 EDLKEGKPYLVLGLLWQVIKIGLFADIELSRNEALIALLREG--ESLEDLMKLSPEELLL 271
E++ PY + W D EL + + L ++L D ++ ++
Sbjct: 8 ENVGNQPPYSRINARWDA------PDDELDNDNSSARLFERSRIKALADEREVVQKKTFT 61
Query: 272 RWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDI 331
+W N HL C +I + D++D + LLE ++ E +P + +++
Sbjct: 62 KWVNSHLARVSC-RITDLYKDLRDGRMLIKLLEVLS----GEMLPKPTKGKMRIHCLENV 116
Query: 332 QRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRYPALHKPENQDIDWGALE 391
+A L++ +R+ + + D+V GN +L L I + R+ + QDI E
Sbjct: 117 DKALQFLKE-QRVHLEN-MGSHDIVDGNHRLVLGLIWTIILRF------QIQDIVVQTQE 168
Query: 392 G-ETREER 398
G ETR +
Sbjct: 169 GRETRSAK 176
>gi|169218211 PREDICTED: similar to plectin 1, partial [Homo
sapiens]
Length = 1369
Score = 65.1 bits (157), Expect = 2e-10
Identities = 62/266 (23%), Positives = 123/266 (46%), Gaps = 42/266 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K W+NK H+I + +DL+ + DG L ++ + D++
Sbjct: 177 QKKTSTKWVNK---------HLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPR---- 223
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K F +N+ +AL+ +VNI +D+ +G P L LGL+W +I +DI+
Sbjct: 224 EKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQ 283
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+S G+S ED ++ +E LL W+ +E + NF++ +D + +
Sbjct: 284 VS-----------GQS-ED---MTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA 328
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
++ + P ++IDM+ + + +++ + AER LG + + DV P
Sbjct: 329 IIHRHKP---------LLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQP 379
Query: 361 --KLNLAFIANLFNRYPALHKPENQD 384
K + ++++L++ P + P+ QD
Sbjct: 380 DEKSIITYVSSLYDAMPRV--PDVQD 403
Score = 43.5 bits (101), Expect = 6e-04
Identities = 53/240 (22%), Positives = 108/240 (45%), Gaps = 31/240 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E + +++T W+N + ++ LY DL D + L E + + P
Sbjct: 172 ERDRVQKKTSTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVL---------SGDSLP 222
Query: 449 KLGGNMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNI 506
+ G M+ KL+N A++ +++ + LV I D+ +GN LTL LIW ++ + ++
Sbjct: 223 REKGRMRFHKLQNVQIALDYLRHR-QVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISD 281
Query: 507 LEEIGGGQKVN-DDIIVNW---VNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPG 562
++ G + + + ++ W + E + + + SS++D ++ + +I +P
Sbjct: 282 IQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNA-----IIHRHKPL 336
Query: 563 SINYDLLKTENLNDDEKLNNAKYAISMA-RKIGARVYALPEDLVEVNP--KMVMTVFACL 619
I+ + + + L N A S+A R +G PED+ P K ++T + L
Sbjct: 337 LIDMNKVYRQT-----NLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSL 391
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 61.2 bits (147), Expect = 3e-09
Identities = 60/229 (26%), Positives = 107/229 (46%), Gaps = 28/229 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E E +++TF W+NS V+ R+ LY+DL D ++ +L E + R+ KP
Sbjct: 38 EREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLS----GERLPKPTKG 93
Query: 449 KLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRY---TLN 505
++ + LEN + A++ K Q + L +G D+ +GN LTL LIW ++ R+ ++
Sbjct: 94 RM--RIHCLENVDKALQFLKEQ-RVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDIS 150
Query: 506 ILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTS----LPVLDLIDAIQP 561
+ E +K D ++ W K++ + +TS + LI +P
Sbjct: 151 VETEDNKEKKSAKDALLLWCQ------MKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRP 204
Query: 562 GSINYDLLKTENLNDDEKLNNAKYAISMARK-IGARVYALPEDLVEVNP 609
I++D LK N + N + A ++A + +G PED+ +P
Sbjct: 205 DLIDFDKLKKSNAH-----YNLQNAFNLAEQHLGLTKLLDPEDISVDHP 248
Score = 56.6 bits (135), Expect = 7e-08
Identities = 53/242 (21%), Positives = 102/242 (42%), Gaps = 39/242 (16%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+N H+ ++ DL+ + DG +L K++ + + + + T
Sbjct: 43 QKKTFTKWVNS---------HLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKG 93
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+ ++ EN++ AL H+ N+G+ D+ +G L LGL+W +I DI
Sbjct: 94 RMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDIS 150
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+ E+ ++ K S ++ LL W I NF+T +D A+
Sbjct: 151 V-------------ETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNA 197
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKD---DIQRAECMLQQAERLGCRQFVTATDVVRG 358
L+ + P +ID L++ + ++Q A + +Q LG + + D+
Sbjct: 198 LIHKHRPD---------LIDFDKLKKSNAHYNLQNAFNLAEQ--HLGLTKLLDPEDISVD 246
Query: 359 NP 360
+P
Sbjct: 247 HP 248
Score = 33.9 bits (76), Expect = 0.46
Identities = 27/119 (22%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 256 ESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGV 315
+ L+D + ++ +W N HL C +I + TD++D + LLE ++ E +
Sbjct: 33 KQLQDEREAVQKKTFTKWVNSHLARVSC-RITDLYTDLRDGRMLIKLLEVLS----GERL 87
Query: 316 PAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRY 374
P + +++ +A L++ +R+ + + D+V GN +L L I + R+
Sbjct: 88 PKPTKGRMRIHCLENVDKALQFLKE-QRVHLEN-MGSHDIVDGNHRLTLGLIWTIILRF 144
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 61.2 bits (147), Expect = 3e-09
Identities = 60/229 (26%), Positives = 107/229 (46%), Gaps = 28/229 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E E +++TF W+NS V+ R+ LY+DL D ++ +L E + R+ KP
Sbjct: 51 EREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLS----GERLPKPTKG 106
Query: 449 KLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRY---TLN 505
++ + LEN + A++ K Q + L +G D+ +GN LTL LIW ++ R+ ++
Sbjct: 107 RM--RIHCLENVDKALQFLKEQ-RVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDIS 163
Query: 506 ILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTS----LPVLDLIDAIQP 561
+ E +K D ++ W K++ + +TS + LI +P
Sbjct: 164 VETEDNKEKKSAKDALLLWCQ------MKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRP 217
Query: 562 GSINYDLLKTENLNDDEKLNNAKYAISMARK-IGARVYALPEDLVEVNP 609
I++D LK N + N + A ++A + +G PED+ +P
Sbjct: 218 DLIDFDKLKKSNAH-----YNLQNAFNLAEQHLGLTKLLDPEDISVDHP 261
Score = 56.6 bits (135), Expect = 7e-08
Identities = 53/242 (21%), Positives = 102/242 (42%), Gaps = 39/242 (16%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+N H+ ++ DL+ + DG +L K++ + + + + T
Sbjct: 56 QKKTFTKWVNS---------HLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKG 106
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+ ++ EN++ AL H+ N+G+ D+ +G L LGL+W +I DI
Sbjct: 107 RMRIHCL---ENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDIS 163
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+ E+ ++ K S ++ LL W I NF+T +D A+
Sbjct: 164 V-------------ETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNA 210
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKD---DIQRAECMLQQAERLGCRQFVTATDVVRG 358
L+ + P +ID L++ + ++Q A + +Q LG + + D+
Sbjct: 211 LIHKHRPD---------LIDFDKLKKSNAHYNLQNAFNLAEQ--HLGLTKLLDPEDISVD 259
Query: 359 NP 360
+P
Sbjct: 260 HP 261
Score = 33.1 bits (74), Expect = 0.79
Identities = 27/119 (22%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 256 ESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGV 315
++L D + ++ +W N HL C +I + TD++D + LLE ++ E +
Sbjct: 46 KALADEREAVQKKTFTKWVNSHLARVSC-RITDLYTDLRDGRMLIKLLEVLS----GERL 100
Query: 316 PAVVIDMSGLREKDDIQRAECMLQQAERLGCRQFVTATDVVRGNPKLNLAFIANLFNRY 374
P + +++ +A L++ +R+ + + D+V GN +L L I + R+
Sbjct: 101 PKPTKGRMRIHCLENVDKALQFLKE-QRVHLEN-MGSHDIVDGNHRLTLGLIWTIILRF 157
>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
Length = 3677
Score = 60.1 bits (144), Expect = 6e-09
Identities = 57/226 (25%), Positives = 104/226 (46%), Gaps = 21/226 (9%)
Query: 391 EGETREERTFRNWMN---SLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPY 447
E E +++TF W+N S + +L+SDL D + L E + K P
Sbjct: 4 EREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTG-------QKLPK 56
Query: 448 PKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTL-NI 506
K + L N N A+ + +N LV IG D+ +GN LTL LIW ++ + + N+
Sbjct: 57 EKGSTRVHALNNVNKALRVLQNN-NVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNV 115
Query: 507 LEEIGGG--QKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSI 564
++ I G Q ++ I+++WV ++ R + + I+ S L + LI + +P
Sbjct: 116 MKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINF--TTSWSDGLALNALIHSHRPDLF 173
Query: 565 NYDLLKTENLNDDEKLNNAKYAISMAR-KIGARVYALPEDLVEVNP 609
+++ + + ++A ++AR ++G PED+ P
Sbjct: 174 DWNSVVCQ----QSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYP 215
Score = 43.1 bits (100), Expect = 8e-04
Identities = 60/257 (23%), Positives = 96/257 (37%), Gaps = 36/257 (14%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+N +H+ +LF+ + DG L ++ ++
Sbjct: 9 QKKTFTKWVNAQFSKFGK-QHI-------ENLFSDLQDGRRLLDLLE----GLTGQKLPK 56
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K T N+N AL +VNIG+ D+ +G L LGL+W +I ++
Sbjct: 57 EKGSTRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVM 116
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+ + L + + E++LL W N + NF+T D A
Sbjct: 117 KN-------------IMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNA 163
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAE-RLGCRQFVTATDVVRGNP 360
L+ P D +VV S QR E A +LG + + DV P
Sbjct: 164 LIHSHRP--DLFDWNSVVCQQSA------TQRLEHAFNIARYQLGIEKLLDPEDVDTTYP 215
Query: 361 --KLNLAFIANLFNRYP 375
K L +I +LF P
Sbjct: 216 DKKSILMYITSLFQVLP 232
Score = 37.0 bits (84), Expect = 0.055
Identities = 48/195 (24%), Positives = 83/195 (42%), Gaps = 27/195 (13%)
Query: 258 LEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYHLLE----QVAPKGDEE 313
+ED + ++ +W N G I N +D++D + LLE Q PK E+
Sbjct: 1 MEDEREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPK--EK 58
Query: 314 GVPAVVIDMSGLREKDDIQRAECMLQ--QAERLGCRQFVTATDVVRGNPKLNLAFIANLF 371
G V +++ +A +LQ + + + +TD+V GN KL L I N+
Sbjct: 59 GSTRV-------HALNNVNKALRVLQNNNVDLVN----IGSTDIVDGNHKLTLGLIWNII 107
Query: 372 NRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVN-PRVN--HLYSDLSDALVIFQ 428
+ + +N L+ +T E+ +W+ N P+VN + + SD L +
Sbjct: 108 LHWQVKNVMKN---IMAGLQ-QTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNA 163
Query: 429 LYEKIKVPV-DWNRV 442
L + + DWN V
Sbjct: 164 LIHSHRPDLFDWNSV 178
>gi|5032287 dystrophin Dp427p1 isoform [Homo sapiens]
Length = 3681
Score = 60.1 bits (144), Expect = 6e-09
Identities = 57/226 (25%), Positives = 104/226 (46%), Gaps = 21/226 (9%)
Query: 391 EGETREERTFRNWMN---SLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPY 447
E E +++TF W+N S + +L+SDL D + L E + K P
Sbjct: 8 EREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTG-------QKLPK 60
Query: 448 PKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTL-NI 506
K + L N N A+ + +N LV IG D+ +GN LTL LIW ++ + + N+
Sbjct: 61 EKGSTRVHALNNVNKALRVLQNN-NVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNV 119
Query: 507 LEEIGGG--QKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSI 564
++ I G Q ++ I+++WV ++ R + + I+ S L + LI + +P
Sbjct: 120 MKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINF--TTSWSDGLALNALIHSHRPDLF 177
Query: 565 NYDLLKTENLNDDEKLNNAKYAISMAR-KIGARVYALPEDLVEVNP 609
+++ + + ++A ++AR ++G PED+ P
Sbjct: 178 DWNSVVCQ----QSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYP 219
Score = 43.1 bits (100), Expect = 8e-04
Identities = 60/257 (23%), Positives = 96/257 (37%), Gaps = 36/257 (14%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+N +H+ +LF+ + DG L ++ ++
Sbjct: 13 QKKTFTKWVNAQFSKFGK-QHI-------ENLFSDLQDGRRLLDLLE----GLTGQKLPK 60
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K T N+N AL +VNIG+ D+ +G L LGL+W +I ++
Sbjct: 61 EKGSTRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVM 120
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+ + L + + E++LL W N + NF+T D A
Sbjct: 121 KN-------------IMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNA 167
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAE-RLGCRQFVTATDVVRGNP 360
L+ P D +VV S QR E A +LG + + DV P
Sbjct: 168 LIHSHRP--DLFDWNSVVCQQSA------TQRLEHAFNIARYQLGIEKLLDPEDVDTTYP 219
Query: 361 --KLNLAFIANLFNRYP 375
K L +I +LF P
Sbjct: 220 DKKSILMYITSLFQVLP 236
>gi|5032283 dystrophin Dp427m isoform [Homo sapiens]
Length = 3685
Score = 60.1 bits (144), Expect = 6e-09
Identities = 57/226 (25%), Positives = 104/226 (46%), Gaps = 21/226 (9%)
Query: 391 EGETREERTFRNWMN---SLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPY 447
E E +++TF W+N S + +L+SDL D + L E + K P
Sbjct: 12 EREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTG-------QKLPK 64
Query: 448 PKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTL-NI 506
K + L N N A+ + +N LV IG D+ +GN LTL LIW ++ + + N+
Sbjct: 65 EKGSTRVHALNNVNKALRVLQNN-NVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNV 123
Query: 507 LEEIGGG--QKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTSLPVLDLIDAIQPGSI 564
++ I G Q ++ I+++WV ++ R + + I+ S L + LI + +P
Sbjct: 124 MKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINF--TTSWSDGLALNALIHSHRPDLF 181
Query: 565 NYDLLKTENLNDDEKLNNAKYAISMAR-KIGARVYALPEDLVEVNP 609
+++ + + ++A ++AR ++G PED+ P
Sbjct: 182 DWNSVVCQ----QSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYP 223
Score = 43.1 bits (100), Expect = 8e-04
Identities = 60/257 (23%), Positives = 96/257 (37%), Gaps = 36/257 (14%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+N +H+ +LF+ + DG L ++ ++
Sbjct: 17 QKKTFTKWVNAQFSKFGK-QHI-------ENLFSDLQDGRRLLDLLE----GLTGQKLPK 64
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+K T N+N AL +VNIG+ D+ +G L LGL+W +I ++
Sbjct: 65 EKGSTRVHALNNVNKALRVLQNNNVDLVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVM 124
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+ + L + + E++LL W N + NF+T D A
Sbjct: 125 KN-------------IMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNA 171
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAE-RLGCRQFVTATDVVRGNP 360
L+ P D +VV S QR E A +LG + + DV P
Sbjct: 172 LIHSHRP--DLFDWNSVVCQQSA------TQRLEHAFNIARYQLGIEKLLDPEDVDTTYP 223
Query: 361 --KLNLAFIANLFNRYP 375
K L +I +LF P
Sbjct: 224 DKKSILMYITSLFQVLP 240
>gi|12025678 actinin, alpha 4 [Homo sapiens]
Length = 911
Score = 57.8 bits (138), Expect = 3e-08
Identities = 81/406 (19%), Positives = 149/406 (36%), Gaps = 89/406 (21%)
Query: 117 SYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTID 176
++ ++++ F W N H+ ++ DG+ L ++ + + +
Sbjct: 47 AWEKQQRKTFTAWCNS---------HLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLP 97
Query: 177 ERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGL 236
+ K ++ N+N AL+ ++ G +V+IGAE++ +G + LG++W +I
Sbjct: 98 KPERGKMRVHKIN---NVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFA 154
Query: 237 FADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDS 296
DI + A +E LL W + NF KD
Sbjct: 155 IQDISVEETSA-------------------KEGLLLWCQRKTAPYKNVNVQNFHISWKDG 195
Query: 297 KAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDV 355
A+ L+ + P+ +I+ LR+ D + + AE+ L + + A D+
Sbjct: 196 LAFNALIHRHRPE---------LIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDI 246
Query: 356 V---RGNPKLNLAFIANLFNRYPALHKPENQDIDWGALEGETREERTFRNWMNSLGVNPR 412
V R + K + ++++ ++ + GA + ET R + L VN
Sbjct: 247 VNTARPDEKAIMTYVSSFYHAFS------------GAQKAETAANRICK----VLAVNQE 290
Query: 413 VNHLYSD----LSDAL-----------------VIFQLYEKIKVPVDWNRVNKPPYPKLG 451
HL D SD L I ++ +K++ D+ RV+KPP
Sbjct: 291 NEHLMEDYEKLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPP----- 345
Query: 452 GNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQ 497
K E C + Q K L +EG + WQ
Sbjct: 346 ---KVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDINNGWQ 388
Score = 50.1 bits (118), Expect = 6e-06
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 25/205 (12%)
Query: 393 ETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKL 450
E ++ +TF W NS ++ ++ D D L + L E I R+ KP K+
Sbjct: 49 EKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVIS----GERLPKPERGKM 104
Query: 451 GGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNILEEI 510
+ K+ N N A++ ++ LV IG +++ +GN +TL +IW ++ R+ +++I
Sbjct: 105 --RVHKINNVNKALDFIASKG-VKLVSIGAEEIVDGNAKMTLGMIWTIILRFA---IQDI 158
Query: 511 GGGQKVNDDIIVNWVNETLREAKKSSSIS---SFKDPKISTSLPVLDLIDAIQPGSINYD 567
+ + ++ W K + + S+KD L LI +P I YD
Sbjct: 159 SVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKD-----GLAFNALIHRHRPELIEYD 213
Query: 568 LLKTENLNDDEKLNNAKYAISMARK 592
L D+ + N A +A K
Sbjct: 214 -----KLRKDDPVTNLNNAFEVAEK 233
Score = 31.2 bits (69), Expect = 3.0
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 12/86 (13%)
Query: 6 VSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITE------NLMA 59
+S E+M E R +F D D G + E ACL GY V + +M+
Sbjct: 762 ISQEQMQEFRASFNHFDKDHGGALGPEEFK-----ACLISLGYDVENDRQGEAEFNRIMS 816
Query: 60 TGDLDQDGRISFDEFIKIFHGLKSTD 85
D + G ++F FI F ++TD
Sbjct: 817 LVDPNHSGLVTFQAFID-FMSRETTD 841
>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
Length = 2390
Score = 57.0 bits (136), Expect = 5e-08
Identities = 64/239 (26%), Positives = 107/239 (44%), Gaps = 30/239 (12%)
Query: 391 EGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYP 448
E E +++TF W+NS V RV LYSDL D + +L E + + + KP
Sbjct: 54 EREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEI----LPKPTKG 109
Query: 449 KLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRY---TLN 505
++ + LEN + A++ K Q K L +G D+ +GN LTL L+W ++ R+ ++
Sbjct: 110 RM--RIHCLENVDKALQFLKEQ-KVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDIS 166
Query: 506 ILEEIGGGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKISTS----LPVLDLIDAIQP 561
+ E +K D ++ W K++ + +TS L ++ +P
Sbjct: 167 VETEDNKEKKSAKDALLLWCQ------MKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRP 220
Query: 562 GSINYDLLKTENLNDDEKLNNAKYAISMARK-IGARVYALPEDLVEVNP--KMVMTVFA 617
DLL E+L N + A ++A K +G PED+ P K ++T A
Sbjct: 221 -----DLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSIITYVA 274
Score = 52.4 bits (124), Expect = 1e-06
Identities = 82/409 (20%), Positives = 154/409 (37%), Gaps = 64/409 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
+K F W+N H+ + DL++ + DG L +++ + + + + T
Sbjct: 59 QKKTFTKWVNS---------HLARVTCRVGDLYSDLRDGRNLLRLLEVLSGEILPKPTKG 109
Query: 182 KKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFADIE 241
+ ++ EN++ AL H+ N+G+ D+ +G L LGL+W +I DI
Sbjct: 110 RMRIHCL---ENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDIS 166
Query: 242 LSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKAYYH 301
+ E+ ++ K S ++ LL W + NF+T +D A+
Sbjct: 167 V-------------ETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNA 213
Query: 302 LLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVRGNP 360
++ + P ++D L++ + + AE+ LG + + DV P
Sbjct: 214 IVHKHRPD---------LLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQP 264
Query: 361 --KLNLAFIANLFNRYPALH------KPENQDIDWGALEGETREER------TFRNWMNS 406
K + ++A ++ + + K + +D A+E E E+ W+
Sbjct: 265 DEKSIITYVATYYHYFSKMKALAVEGKRIGKVLD-HAMEAERLVEKYESLASELLQWIEQ 323
Query: 407 LGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKLGGNMK--------KLE 458
V L + LS Q + + V KPP GN++ KL
Sbjct: 324 TIVTLNDRQLANSLSGVQNQLQSFN------SYRTVEKPPKFTEKGNLEVLLFTIQSKLR 377
Query: 459 NCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTLNIL 507
N V + S + + L + LAL +L+R+ L L
Sbjct: 378 ANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLEQL 426
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 56.6 bits (135), Expect = 7e-08
Identities = 38/143 (26%), Positives = 73/143 (51%), Gaps = 18/143 (12%)
Query: 396 EERTFRNWMN---SLGVNPRVNHLYSDLSDALVIFQLYEKIKVPVDWNRVNKPPYPKLGG 452
+++TF W+N S P +N +++DL D + L E + PK G
Sbjct: 33 QKKTFTKWINARFSKSGKPPINDMFTDLKDGRKLLDLLEGL---------TGTSLPKERG 83
Query: 453 NMK--KLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTLALIWQLMRRYTL-NILEE 509
+ + L N N +++ +Q LV IGG D+ +GN LTL L+W ++ + + +++++
Sbjct: 84 STRVHALNNVNRVLQV-LHQNNVELVNIGGTDIVDGNHKLTLGLLWSIILHWQVKDVMKD 142
Query: 510 IGGG--QKVNDDIIVNWVNETLR 530
+ Q ++ I+++WV +T R
Sbjct: 143 VMSDLQQTNSEKILLSWVRQTTR 165
Score = 52.4 bits (124), Expect = 1e-06
Identities = 60/276 (21%), Positives = 104/276 (37%), Gaps = 39/276 (14%)
Query: 105 GTSEQSSVGTQHS--YSEEEKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIV 162
G +E S + S +++ +K F WIN P ND+F + DG
Sbjct: 14 GQNEFSDIIKSRSDEHNDVQKKTFTKWINARFSKSG--------KPPINDMFTDLKDGRK 65
Query: 163 LCKMINLSVPDTIDERTINKKKLTPFTIQENLNLALNSASAIGCHVVNIGAEDLKEGKPY 222
L ++ ++ + ++ T N+N L +VNIG D+ +G
Sbjct: 66 LLDLLEGLTGTSLPK----ERGSTRVHALNNVNRVLQVLHQNNVELVNIGGTDIVDGNHK 121
Query: 223 LVLGLLWQVIKIGLFADIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAG 282
L LGLLW +I D+ + + DL + + E++LL W
Sbjct: 122 LTLGLLWSIILHWQVKDV-------------MKDVMSDLQQTNSEKILLSWVRQTTRPYS 168
Query: 283 CNKIGNFSTDIKDSKAYYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAE 342
+ NF+T D A+ +L + P + + + I+R E +A+
Sbjct: 169 QVNVLNFTTSWTDGLAFNAVLHRHKPD---------LFSWDKVVKMSPIERLEHAFSKAQ 219
Query: 343 R-LGCRQFVTATDVVRGNP--KLNLAFIANLFNRYP 375
LG + + DV P K + ++ +LF P
Sbjct: 220 TYLGIEKLLDPEDVAVQLPDKKSIIMYLTSLFEVLP 255
>gi|105990514 filamin B, beta (actin binding protein 278) [Homo
sapiens]
Length = 2602
Score = 55.8 bits (133), Expect = 1e-07
Identities = 57/250 (22%), Positives = 113/250 (45%), Gaps = 29/250 (11%)
Query: 375 PALHKPENQDIDWGALEGETREERTFRNWMNS--LGVNPRVNHLYSDLSDALVIFQLYEK 432
P K +D W ++ + TF W N VN R+ +L +DLSD L + L E
Sbjct: 2 PVTEKDLAEDAPWKKIQ-----QNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEV 56
Query: 433 IKVPVDWNRVNKPPYPKLGGNMKKLENCNYAVELGKNQAKFSLVGIGGQDLNEGNRTLTL 492
+ + + ++ P + +LEN + A+E ++ LV I + + +GN L L
Sbjct: 57 LSQKRMYRKYHQRPTFR----QMQLENVSVALEF-LDRESIKLVSIDSKAIVDGNLKLIL 111
Query: 493 ALIWQLMRRYTLN--ILEEIG---GGQKVNDDIIVNWVNETLREAKKSSSISSFKDPKIS 547
L+W L+ Y+++ + E+ G ++ ++ W+ + ++ +++D K
Sbjct: 112 GLVWTLILHYSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKAL 171
Query: 548 TSLPVLDLIDAIQPGSINYDLLKTENLNDDEKLNNAKYAISMARK-IGARVYALPEDLV- 605
+ L+D+ PG E+ + + ++NA+ A+ A +G PE+++
Sbjct: 172 GA-----LVDSCAPGLCP----DWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIH 222
Query: 606 -EVNPKMVMT 614
+V+ VMT
Sbjct: 223 PDVDEHSVMT 232
Score = 46.2 bits (108), Expect = 9e-05
Identities = 56/258 (21%), Positives = 108/258 (41%), Gaps = 41/258 (15%)
Query: 122 EKYAFVNWINKALENDPDCRHVIPMNPNTNDLFNAVGDGIVLCKMINLSVPDTIDERTIN 181
++ F W N+ H+ +N +L + DG+ L ++ + +R
Sbjct: 18 QQNTFTRWCNE---------HLKCVNKRIGNLQTDLSDGLRLIALLEV----LSQKRMYR 64
Query: 182 KKKLTPFTIQ---ENLNLALNSASAIGCHVVNIGAEDLKEGKPYLVLGLLWQVIKIGLFA 238
K P Q EN+++AL +V+I ++ + +G L+LGL+W +I L
Sbjct: 65 KYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLI---LHY 121
Query: 239 DIELSRNEALIALLREGESLEDLMKLSPEELLLRWANYHLENAGCNKIGNFSTDIKDSKA 298
I + + E E +D K +P++ LL W + I NF+ + +D KA
Sbjct: 122 SISMP--------VWEDEGDDDAKKQTPKQRLLGWIQNKIPYL---PITNFNQNWQDGKA 170
Query: 299 YYHLLEQVAPKGDEEGVPAVVIDMSGLREKDDIQRAECMLQQAER-LGCRQFVTATDVVR 357
L++ A P + D + + A +QQA+ LG Q +T +++
Sbjct: 171 LGALVDSCA--------PGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEII- 221
Query: 358 GNPKLNLAFIANLFNRYP 375
+P ++ + +++P
Sbjct: 222 -HPDVDEHSVMTYLSQFP 238
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,177,292
Number of Sequences: 37866
Number of extensions: 1007617
Number of successful extensions: 2729
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 2318
Number of HSP's gapped (non-prelim): 369
length of query: 627
length of database: 18,247,518
effective HSP length: 108
effective length of query: 519
effective length of database: 14,157,990
effective search space: 7347996810
effective search space used: 7347996810
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.