Search of human proteins with 16757970

Search of human proteins with 16757970

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16757970 niban protein isoform 2 [Homo sapiens]
         (928 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16757970 niban protein isoform 2 [Homo sapiens]                   1853   0.0  
gi|51093863 hypothetical protein LOC64855 isoform 1 [Homo sapiens]    444   e-124
gi|79750824 hypothetical protein LOC64855 isoform 2 [Homo sapiens]    434   e-121
gi|148664236 B-cell novel protein 1 isoform b [Homo sapiens]          237   3e-62
gi|31542207 B-cell novel protein 1 isoform a [Homo sapiens]           237   3e-62
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             50   1e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    48   4e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    47   1e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    47   1e-04
gi|31542634 filamin A interacting protein 1 [Homo sapiens]             46   1e-04
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        46   2e-04
gi|30795231 brain abundant, membrane attached signal protein 1 [...    44   5e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           44   5e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    44   7e-04
gi|6912246 CD3E antigen, epsilon polypeptide associated protein ...    44   7e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    44   7e-04
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              44   7e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    43   0.001
gi|7662058 tectonin beta-propeller repeat containing 2 [Homo sap...    43   0.001
gi|4559408 colony stimulating factor 2 receptor, beta precursor ...    42   0.002
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       42   0.002
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi...    42   0.003
gi|117676384 splicing factor, arginine/serine-rich 2, interactin...    42   0.003
gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a ...    42   0.003
gi|31543148 hypothetical protein LOC79173 [Homo sapiens]               42   0.003
gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin prote...    42   0.003
gi|4502805 chromogranin A precursor [Homo sapiens]                     41   0.006
gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b ...    41   0.006
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         41   0.006
gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [H...    41   0.006

>gi|16757970 niban protein isoform 2 [Homo sapiens]
          Length = 928

 Score = 1853 bits (4800), Expect = 0.0
 Identities = 928/928 (100%), Positives = 928/928 (100%)

Query: 1   MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLK 60
           MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLK
Sbjct: 1   MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLK 60

Query: 61  TKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILP 120
           TKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILP
Sbjct: 61  TKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILP 120

Query: 121 AGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHE 180
           AGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHE
Sbjct: 121 AGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHE 180

Query: 181 AADQKRFSALLSDCVRHLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQI 240
           AADQKRFSALLSDCVRHLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQI
Sbjct: 181 AADQKRFSALLSDCVRHLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQI 240

Query: 241 LSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRA 300
           LSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRA
Sbjct: 241 LSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRA 300

Query: 301 LTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSS 360
           LTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSS
Sbjct: 301 LTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSS 360

Query: 361 GFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERL 420
           GFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERL
Sbjct: 361 GFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERL 420

Query: 421 QDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQGEASKTAVAIEKVKLRV 480
           QDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQGEASKTAVAIEKVKLRV
Sbjct: 421 QDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQGEASKTAVAIEKVKLRV 480

Query: 481 LKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENV 540
           LKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENV
Sbjct: 481 LKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENV 540

Query: 541 YEEILHQILLDETLKVIKEAAILKKHNLFEDNMALPSESVSSLTDLKPPTGSNQASPARR 600
           YEEILHQILLDETLKVIKEAAILKKHNLFEDNMALPSESVSSLTDLKPPTGSNQASPARR
Sbjct: 541 YEEILHQILLDETLKVIKEAAILKKHNLFEDNMALPSESVSSLTDLKPPTGSNQASPARR 600

Query: 601 ASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRV 660
           ASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRV
Sbjct: 601 ASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRV 660

Query: 661 DDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASV 720
           DDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASV
Sbjct: 661 DDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASV 720

Query: 721 EVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEA 780
           EVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEA
Sbjct: 721 EVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEA 780

Query: 781 HGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQ 840
           HGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQ
Sbjct: 781 HGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQ 840

Query: 841 QEGCTLGSDPICLSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPN 900
           QEGCTLGSDPICLSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPN
Sbjct: 841 QEGCTLGSDPICLSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPN 900

Query: 901 PDVLLSHKDDVKEGEGGQESFPELPSEE 928
           PDVLLSHKDDVKEGEGGQESFPELPSEE
Sbjct: 901 PDVLLSHKDDVKEGEGGQESFPELPSEE 928


>gi|51093863 hypothetical protein LOC64855 isoform 1 [Homo sapiens]
          Length = 746

 Score =  444 bits (1142), Expect = e-124
 Identities = 273/769 (35%), Positives = 409/769 (53%), Gaps = 46/769 (5%)

Query: 1   MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLK 60
           MG   S+ LD+ +  +I  KT   +  F  +Y  QY VA  N +R E+E      +Q L 
Sbjct: 1   MGDVLSTHLDDARRQHIAEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLW 60

Query: 61  TKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILP 120
            K PL    I++   L Q  ED KKW+ R+ +V ++Y +  YENK AY+R   P+  I  
Sbjct: 61  RKVPLDE-RIVFSGNLFQHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINS 119

Query: 121 AGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHE 180
           AG K+LTS D+Y  L     P   A   K  + P +  P +FP+ LW P+ RH YFC   
Sbjct: 120 AGYKILTSVDQYLELIGNSLPGTTA---KSGSAPILKCPTQFPLILWHPYARHYYFCMMT 176

Query: 181 AADQKRFSALLSDCVRHLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQI 240
            A+Q ++ A+L DC+RH N+   +    E  AF +A++ +RQ K  YG+WEM+ G+E+QI
Sbjct: 177 EAEQDKWQAVLQDCIRHCNNGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQI 236

Query: 241 LSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRA 300
           LSNLVMEEL P L+ +L P++KGK  +R+R W+ + +  Y +V  Q       +  + + 
Sbjct: 237 LSNLVMEELGPELKAELGPRLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQ 296

Query: 301 LTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSS 360
           +   ++  IR+DMDQI+ SK +L  KI+A +   AE      VQP++ SILE LM P S 
Sbjct: 297 VQPAMQAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQ 356

Query: 361 GFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERL 420
           GF+EVR +F KEV +++ N        +L E++++L  L  H +KM+ CY K+  L  RL
Sbjct: 357 GFTEVRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESL--RL 414

Query: 421 QDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQGEASKTAV--AIEKVKL 478
             L+ RF      +  QR Q +M+E M+NAV+TFE LL   L    +K  +  +I++V  
Sbjct: 415 DGLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLE 474

Query: 479 RVLKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVE 538
           RVLK+YDYDSS++RK+ F+EAL+QI++P + K LA TCK EL ++++ IF D    I VE
Sbjct: 475 RVLKKYDYDSSSVRKRFFREALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVE 534

Query: 539 NVYEEILHQILLDETLKVIKEAAILKKHNLFEDNMALPSE--SVSSLTDLKPPTGSNQAS 596
           N YEE++ Q ++ + L+ +KEAA+ +KHNL+ D+M + +   ++  L +  P     + S
Sbjct: 535 NTYEEVVLQTVMKDILQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYS 594

Query: 597 PARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVI 656
            +    +  P    S TL       SE+ ++ +   S+ + E + LP  + P        
Sbjct: 595 NSGGGGSPSPSTPESATL-------SEKRRRAKQVVSVVQDEEVGLPFEASPE------- 640

Query: 657 ISRVDDPVVNPVATEDTAGL--PGTCSSELEFGGTLEDEEPAQEEPEPITA----SGSLK 710
                 P  +P    +  GL   G         G L +  PA E P+P  A    S    
Sbjct: 641 ----SPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPAS 696

Query: 711 ALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIH 759
            L+ LL       VD  P    D         +   E+   PS   A+H
Sbjct: 697 PLQHLLPGKA---VDLGPPKPSD---------QETGEQVSSPSSHPALH 733



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 6/103 (5%)

Query: 725 DSAPVMEEDTNGESHVPQENEEEE----EKEPSQAAAIHPDNCEESE-VSEREAQPPCPE 779
           +SA + E+    +  V    +EE     E  P       PD   E   +  +  +P  P 
Sbjct: 608 ESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPP 667

Query: 780 AHGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTL 822
             G  L G P   SP  P A+   +  P  P++  LPG+A  L
Sbjct: 668 PAGPLLNGAPAGESP-QPKAAPEASSPPASPLQHLLPGKAVDL 709


>gi|79750824 hypothetical protein LOC64855 isoform 2 [Homo sapiens]
          Length = 733

 Score =  434 bits (1117), Expect = e-121
 Identities = 267/750 (35%), Positives = 399/750 (53%), Gaps = 46/750 (6%)

Query: 20  KTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLKTKPPLAPGTILYEAELSQF 79
           KT   +  F  +Y  QY VA  N +R E+E      +Q L  K PL    I++   L Q 
Sbjct: 7   KTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLWRKVPLDE-RIVFSGNLFQH 65

Query: 80  SEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILPAGGKVLTSEDEYNLLSDRH 139
            ED KKW+ R+ +V ++Y +  YENK AY+R   P+  I  AG K+LTS D+Y  L    
Sbjct: 66  QEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSAGYKILTSVDQYLELIGNS 125

Query: 140 FPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHEAADQKRFSALLSDCVRHLN 199
            P   A   K  + P +  P +FP+ LW P+ RH YFC    A+Q ++ A+L DC+RH N
Sbjct: 126 LPGTTA---KSGSAPILKCPTQFPLILWHPYARHYYFCMMTEAEQDKWQAVLQDCIRHCN 182

Query: 200 HDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQILSNLVMEELLPTLQTDLLP 259
           +   +    E  AF +A++ +RQ K  YG+WEM+ G+E+QILSNLVMEEL P L+ +L P
Sbjct: 183 NGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQILSNLVMEELGPELKAELGP 242

Query: 260 KMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRALTKGLEGTIRSDMDQIVNS 319
           ++KGK  +R+R W+ + +  Y +V  Q       +  + + +   ++  IR+DMDQI+ S
Sbjct: 243 RLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQVQPAMQAVIRTDMDQIITS 302

Query: 320 KNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSSGFSEVRVLFEKEVNEVSQN 379
           K +L  KI+A +   AE      VQP++ SILE LM P S GF+EVR +F KEV +++ N
Sbjct: 303 KEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLN 362

Query: 380 FQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERLQDLKSRFRFPHIDLVVQRT 439
                   +L E++++L  L  H +KM+ CY K+  L  RL  L+ RF      +  QR 
Sbjct: 363 VINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESL--RLDGLQQRFDVSSTSVFKQRA 420

Query: 440 QNYMQELMENAVFTFEQLLSPHLQGEASKTAV--AIEKVKLRVLKQYDYDSSTIRKKIFQ 497
           Q +M+E M+NAV+TFE LL   L    +K  +  +I++V  RVLK+YDYDSS++RK+ F+
Sbjct: 421 QIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLERVLKKYDYDSSSVRKRFFR 480

Query: 498 EALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVENVYEEILHQILLDETLKVI 557
           EAL+QI++P + K LA TCK EL ++++ IF D    I VEN YEE++ Q ++ + L+ +
Sbjct: 481 EALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAV 540

Query: 558 KEAAILKKHNLFEDNMALPSE--SVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLS 615
           KEAA+ +KHNL+ D+M + +   ++  L +  P     + S +    +  P    S TL 
Sbjct: 541 KEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATL- 599

Query: 616 NEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAG 675
                 SE+ ++ +   S+ + E + LP  + P              P  +P    +  G
Sbjct: 600 ------SEKRRRAKQVVSVVQDEEVGLPFEASPE-----------SPPPASPDGVTEIRG 642

Query: 676 L--PGTCSSELEFGGTLEDEEPAQEEPEPITA----SGSLKALRKLLTASVEVPVDSAPV 729
           L   G         G L +  PA E P+P  A    S     L+ LL       VD  P 
Sbjct: 643 LLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKA---VDLGPP 699

Query: 730 MEEDTNGESHVPQENEEEEEKEPSQAAAIH 759
              D         +   E+   PS   A+H
Sbjct: 700 KPSD---------QETGEQVSSPSSHPALH 720



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 6/103 (5%)

Query: 725 DSAPVMEEDTNGESHVPQENEEEE----EKEPSQAAAIHPDNCEESE-VSEREAQPPCPE 779
           +SA + E+    +  V    +EE     E  P       PD   E   +  +  +P  P 
Sbjct: 595 ESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPP 654

Query: 780 AHGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTL 822
             G  L G P   SP  P A+   +  P  P++  LPG+A  L
Sbjct: 655 PAGPLLNGAPAGESP-QPKAAPEASSPPASPLQHLLPGKAVDL 696


>gi|148664236 B-cell novel protein 1 isoform b [Homo sapiens]
          Length = 651

 Score =  237 bits (605), Expect = 3e-62
 Identities = 156/560 (27%), Positives = 265/560 (47%), Gaps = 7/560 (1%)

Query: 1   MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLK 60
           MGG  SS LD+ +  ++RG+ +  ++NF P Y  Q + +    +  E+  Q    SQ L+
Sbjct: 32  MGGRPSSPLDKQQRQHLRGQVDTLLRNFLPCYRGQLAASVLRQISRELGPQEPTGSQLLR 91

Query: 61  TKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILP 120
           +K    P    +   L+Q      +W+  + V++ D  +E + +KE Y+ G         
Sbjct: 92  SKK--LPRVREHRGPLTQLRGHPPRWQPIFCVLRGDGRLEWFSHKEEYENGGHCLGSTAL 149

Query: 121 AGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHE 180
            G  +LTS+ EY  L D   P+ L    +E     + +P  FP++L  PF RH  F    
Sbjct: 150 TGYTLLTSQREYLRLLDALCPESLGDHTQEEPDSLLEVPVSFPLFLQHPFRRHLCFSAAT 209

Query: 181 AADQKRFSALLSDCVRHLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQI 240
              Q  +   L   +R       +     A+AFL+AV+ +RQ +GH+G  ++  G + ++
Sbjct: 210 REAQHAWRLALQGGIRLQGTVLQRSQAPAARAFLDAVRLYRQHQGHFGDDDVTLGSDAEV 269

Query: 241 LSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRA 300
           L+ ++M E LP L+   LP ++G    R   W  LL+  +  V    S GL A + E   
Sbjct: 270 LTAVLMREQLPALRAQTLPGLRGAGRARAWAWTELLDAVHAAVLAGASAGLCAFQPEKDE 329

Query: 301 LTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSS 360
           L   LE TIR D+DQ++  +  + G+++  +  P E      V P L  +++ L+  V +
Sbjct: 330 LLASLEKTIRPDVDQLLRQRARVAGRLRTDIRGPLESCLRREVDPQLPRVVQTLLRTVEA 389

Query: 361 GFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERL 420
               VR L  + ++ +S   + +    +L+  +     +P     M+ CY +      RL
Sbjct: 390 SLEAVRTLLAQGMDRLSHRLRQSPSGTRLRREVYSFGEMPWDLALMQTCYREAERSRGRL 449

Query: 421 QDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQG--EASKTAVAIEKVKL 478
             L + F F  +  +V   Q+  Q+LM +AV TF QL    L       + A  +E+V+ 
Sbjct: 450 GQLAAPFGFLGMQSLVFGAQDLAQQLMADAVATFLQLADQCLTTALNCDQAAQRLERVRG 509

Query: 479 RVLKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVE 538
           RVLK++  DS   +++  +   + I LP V   L   CK EL ++E  + A  +  +  E
Sbjct: 510 RVLKKFKSDSGLAQRRFIRGWGLCIFLPFVLSQLEPGCKKELPEFEGDVLAVGSQALTTE 569

Query: 539 NVYEEILHQILL---DETLK 555
            +YE+++   LL   D+ LK
Sbjct: 570 GIYEDVIRGCLLQRIDQELK 589


>gi|31542207 B-cell novel protein 1 isoform a [Homo sapiens]
          Length = 697

 Score =  237 bits (605), Expect = 3e-62
 Identities = 156/560 (27%), Positives = 265/560 (47%), Gaps = 7/560 (1%)

Query: 1   MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLK 60
           MGG  SS LD+ +  ++RG+ +  ++NF P Y  Q + +    +  E+  Q    SQ L+
Sbjct: 32  MGGRPSSPLDKQQRQHLRGQVDTLLRNFLPCYRGQLAASVLRQISRELGPQEPTGSQLLR 91

Query: 61  TKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILP 120
           +K    P    +   L+Q      +W+  + V++ D  +E + +KE Y+ G         
Sbjct: 92  SKK--LPRVREHRGPLTQLRGHPPRWQPIFCVLRGDGRLEWFSHKEEYENGGHCLGSTAL 149

Query: 121 AGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHE 180
            G  +LTS+ EY  L D   P+ L    +E     + +P  FP++L  PF RH  F    
Sbjct: 150 TGYTLLTSQREYLRLLDALCPESLGDHTQEEPDSLLEVPVSFPLFLQHPFRRHLCFSAAT 209

Query: 181 AADQKRFSALLSDCVRHLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQI 240
              Q  +   L   +R       +     A+AFL+AV+ +RQ +GH+G  ++  G + ++
Sbjct: 210 REAQHAWRLALQGGIRLQGTVLQRSQAPAARAFLDAVRLYRQHQGHFGDDDVTLGSDAEV 269

Query: 241 LSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRA 300
           L+ ++M E LP L+   LP ++G    R   W  LL+  +  V    S GL A + E   
Sbjct: 270 LTAVLMREQLPALRAQTLPGLRGAGRARAWAWTELLDAVHAAVLAGASAGLCAFQPEKDE 329

Query: 301 LTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSS 360
           L   LE TIR D+DQ++  +  + G+++  +  P E      V P L  +++ L+  V +
Sbjct: 330 LLASLEKTIRPDVDQLLRQRARVAGRLRTDIRGPLESCLRREVDPQLPRVVQTLLRTVEA 389

Query: 361 GFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERL 420
               VR L  + ++ +S   + +    +L+  +     +P     M+ CY +      RL
Sbjct: 390 SLEAVRTLLAQGMDRLSHRLRQSPSGTRLRREVYSFGEMPWDLALMQTCYREAERSRGRL 449

Query: 421 QDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQG--EASKTAVAIEKVKL 478
             L + F F  +  +V   Q+  Q+LM +AV TF QL    L       + A  +E+V+ 
Sbjct: 450 GQLAAPFGFLGMQSLVFGAQDLAQQLMADAVATFLQLADQCLTTALNCDQAAQRLERVRG 509

Query: 479 RVLKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVE 538
           RVLK++  DS   +++  +   + I LP V   L   CK EL ++E  + A  +  +  E
Sbjct: 510 RVLKKFKSDSGLAQRRFIRGWGLCIFLPFVLSQLEPGCKKELPEFEGDVLAVGSQALTTE 569

Query: 539 NVYEEILHQILL---DETLK 555
            +YE+++   LL   D+ LK
Sbjct: 570 GIYEDVIRGCLLQRIDQELK 589


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 61/247 (24%), Positives = 89/247 (36%), Gaps = 24/247 (9%)

Query: 586 LKPPTGSN------QASPARRASAILPGVLGSETLSNEVFQE-SEEEKQPEV---PSSLA 635
           L PP G+       Q S A  AS    GV G +  S     E +E E  P +   P S  
Sbjct: 299 LPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPP 358

Query: 636 KGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTCSSE---LEFGGTLED 692
           +G       P+P PDG +Q      + P   P A          C+ E     F   + +
Sbjct: 359 EGP------PNPGPDGGKQ----DGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPE 408

Query: 693 EEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEP 752
            +    E +P   S +  A      +  +    + PV+ ++  G      E E E E EP
Sbjct: 409 GDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEP 468

Query: 753 SQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPASGGLTEEPLGPME 812
            + A   P+       +     PP P++  +        G  ASPP +      P+ P  
Sbjct: 469 ERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAA-ESPPVEPGP 527

Query: 813 GELPGEA 819
           G L  EA
Sbjct: 528 GSLDAEA 534


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 64/304 (21%), Positives = 106/304 (34%), Gaps = 35/304 (11%)

Query: 588 PPTGSNQASPARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLP---- 643
           PP  S    P ++A      V  SE  S+E    SEEEK+P   + ++K  +   P    
Sbjct: 299 PPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKA 358

Query: 644 -----------------GPSPPPDGTEQVI---ISRVDDPVVNPVAT--EDTAGLPGTCS 681
                             PS P   T+            P V P A   +   G     +
Sbjct: 359 AESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLT 418

Query: 682 SELEFGGTLEDEEPAQEE-PEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHV 740
            + +   + E+   ++EE  + + A+   KA  K   A++ +P   AP    D++ +S  
Sbjct: 419 RKADSSSSEEESSSSEEEKTKKMVATTKPKATAK---AALSLPAKQAPQGSRDSSSDSD- 474

Query: 741 PQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPAS 800
              +EEEEEK    A    P          + A     +A         +          
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLK 534

Query: 801 GGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPICLSESQVSE 860
           G  +  P  P           LTA  G+  K +EE +  +++   + S    L + + +E
Sbjct: 535 GKGSPRPQAPK----ANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNE 590

Query: 861 EQEE 864
             +E
Sbjct: 591 AAKE 594



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 55/301 (18%), Positives = 103/301 (34%), Gaps = 40/301 (13%)

Query: 622 SEEEKQPEVPSSLAKGESLSLPGPSPPPD----GT---------EQVIISRVDD------ 662
           S+EE++ + P     G   S+P PS PP     GT         +Q + S  D       
Sbjct: 272 SDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDS 331

Query: 663 -------PVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKL 715
                  P    V ++ T   P       E      D + ++++  P   +G+ K     
Sbjct: 332 SSEEEKKPPTKAVVSKATT-KPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNK 390

Query: 716 LTASVEVP-VDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQ 774
              + + P V  A   ++   G   +     +    E   +++       E E +++   
Sbjct: 391 PAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSS-------EEEKTKKMVA 443

Query: 775 PPCPEAHGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTE 834
              P+A  +     P   +P     S   ++      E E   ++      +   G    
Sbjct: 444 TTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAP 503

Query: 835 EGDASQQEGCTLGSDPICLSESQVSEEQEEMG-----GQSSAAQATASVNAEEIKVARIH 889
              AS ++G    S+     +S   EE++  G      Q+  A  T+++ A+  K A+  
Sbjct: 504 SKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNS 563

Query: 890 E 890
           E
Sbjct: 564 E 564


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 68/312 (21%), Positives = 116/312 (37%), Gaps = 26/312 (8%)

Query: 617 EVFQESEEEKQPEVPSSLAKGESLSLPGPS-PPPDGTEQVIISRVDDPVVNPVATEDTAG 675
           E  +E EEE + E     AK   +    P     +G ++    + ++   +  A  D A 
Sbjct: 490 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 549

Query: 676 LPGT---CSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEE 732
             G+    SSE E G   E E  A+ E E   A    K   K    + +  + +   +E+
Sbjct: 550 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 609

Query: 733 DTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVG 792
               +S VP+   EE+ K P   + +           E + + P P++  EE G  P   
Sbjct: 610 PEKAKSPVPKSPVEEKGKSPVPKSPV-----------EEKGKSPVPKSPVEEKGKSP--- 655

Query: 793 SPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPIC 852
            P SP    G +     P+E +           E +      +G+  ++E   +   P  
Sbjct: 656 VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP-- 713

Query: 853 LSESQVSEEQEEMGGQSSAAQATASVN----AEEIKVARIHECQWVVEDAPNPDVLLSHK 908
             E +V +++E+        +A + V     AE + + +  +     E       L   K
Sbjct: 714 -KEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEK 772

Query: 909 DDVKE-GEGGQE 919
           +  K  GEGG E
Sbjct: 773 EKEKAGGEGGSE 784


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 68/312 (21%), Positives = 116/312 (37%), Gaps = 26/312 (8%)

Query: 617 EVFQESEEEKQPEVPSSLAKGESLSLPGPS-PPPDGTEQVIISRVDDPVVNPVATEDTAG 675
           E  +E EEE + E     AK   +    P     +G ++    + ++   +  A  D A 
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAE 173

Query: 676 LPGT---CSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEE 732
             G+    SSE E G   E E  A+ E E   A    K   K    + +  + +   +E+
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEK 233

Query: 733 DTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVG 792
               +S VP+   EE+ K P   + +           E + + P P++  EE G  P   
Sbjct: 234 PEKAKSPVPKSPVEEKGKSPVPKSPV-----------EEKGKSPVPKSPVEEKGKSP--- 279

Query: 793 SPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPIC 852
            P SP    G +     P+E +           E +      +G+  ++E   +   P  
Sbjct: 280 VPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP-- 337

Query: 853 LSESQVSEEQEEMGGQSSAAQATASVN----AEEIKVARIHECQWVVEDAPNPDVLLSHK 908
             E +V +++E+        +A + V     AE + + +  +     E       L   K
Sbjct: 338 -KEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEK 396

Query: 909 DDVKE-GEGGQE 919
           +  K  GEGG E
Sbjct: 397 EKEKAGGEGGSE 408


>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
          Length = 1213

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 72/329 (21%), Positives = 138/329 (41%), Gaps = 23/329 (6%)

Query: 184 QKRFSALLSDCVR-HLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQILS 242
           ++ FS   S+C + HLN +  K +T +    LE V+   + K    S   +   E+ +  
Sbjct: 439 EEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVK--SRVKELECSESRLEKAELSLKD 496

Query: 243 NLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRALT 302
           +L   +    +  D    M  K    +R   GL  + + + Q +V +    L EE + L 
Sbjct: 497 DLTKLKSFTVMLVDERKNMMEKIKQEERKVDGL-NKNFKVEQGKVMDVTEKLIEESKKLL 555

Query: 303 KGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSSGF 362
           K L+  +   +  +   ++ LIGK+K+   + +E SC   +       +EE+   ++ G 
Sbjct: 556 K-LKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGR 614

Query: 363 SEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCY-----------T 411
           S  R   E    E ++  + T +  +LK+ L +L  +    +K E  Y            
Sbjct: 615 S--RKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQD 672

Query: 412 KVNLLHERLQDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQGEASKTAV 471
           K N L ++L+++K +      +  +++ +   QE      F  E+  S  L+ E      
Sbjct: 673 KANFLSQQLEEIKHQIA---KNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKE 729

Query: 472 AIEKV--KLRVLKQYDYDSSTIRKKIFQE 498
            I ++  K   L Q   D S ++++  +E
Sbjct: 730 KIHELMNKEDQLSQLQVDYSVLQQRFMEE 758


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 61/228 (26%), Positives = 83/228 (36%), Gaps = 31/228 (13%)

Query: 624 EEKQPEVPSSLAKGESLSLPGP---SPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTC 680
           E  QP  P S +     S P P      P G ++ + S      VN        GLP   
Sbjct: 628 ETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVN--------GLPRAV 679

Query: 681 SSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNG--ES 738
              L +     D    +E    +     +     LLT   +VP+  APV  +  NG  E 
Sbjct: 680 PLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTP-QVPL--APVQPQ-ANGKEEE 735

Query: 739 HVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPP 798
              +E+EEEEE++  +      +  EE E  E E +     A GE LG           P
Sbjct: 736 EEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLG-----------P 784

Query: 799 ASGGLTEEPLGPMEGELPGEACTLTA---HEGRGGKCTEEGDASQQEG 843
            SG  +E      +    G   TL A    E RG     +GD   +EG
Sbjct: 785 RSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEG 832


>gi|30795231 brain abundant, membrane attached signal protein 1
           [Homo sapiens]
          Length = 227

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 22/222 (9%)

Query: 688 GTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEE 747
           G   +EE   +E EP  A+   +A         E P   A    E+  GE       EE 
Sbjct: 28  GAATEEEGTPKESEPQAAAEPAEAKE-----GKEKPDQDAEGKAEEKEGEKDAAAAKEEA 82

Query: 748 EEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPASGGLTEEP 807
            + EP +         E  +  E+E   P P A GE     P+    A+ PA      E 
Sbjct: 83  PKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEA----PKAAEAAAAPA------ES 132

Query: 808 LGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPICLSESQVSEEQEEMGG 867
             P  GE P +       EG   K       + QE  + G+ P   S+   SE       
Sbjct: 133 AAPAAGEEPSK------EEGEPKKTEAPAAPAAQETKSDGA-PASDSKPGSSEAAPSSKE 185

Query: 868 QSSAAQATASVNAEEIKVARIHECQWVVEDAPNPDVLLSHKD 909
             +A +A +S    +   A   E + V   A N D  ++ K+
Sbjct: 186 TPAATEAPSSTPKAQGPAASAEEPKPVEAPAANSDQTVTVKE 227



 Score = 36.2 bits (82), Expect = 0.15
 Identities = 39/162 (24%), Positives = 58/162 (35%), Gaps = 13/162 (8%)

Query: 724 VDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGE 783
           V+     E+D   E    +E    +E EP QAAA   +  E  E  +++A+    E  GE
Sbjct: 14  VNDEKAKEKDKKAEGAATEEEGTPKESEP-QAAAEPAEAKEGKEKPDQDAEGKAEEKEGE 72

Query: 784 -ELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQE 842
            +     E    A P  + G  E    P +     +A    A  G   K  E   A    
Sbjct: 73  KDAAAAKEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAA---- 128

Query: 843 GCTLGSDPICLSESQVSEEQEEMGGQSSAAQATASVNAEEIK 884
                  P   +     EE  +  G+    +A A+  A+E K
Sbjct: 129 -------PAESAAPAAGEEPSKEEGEPKKTEAPAAPAAQETK 163


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 65/303 (21%), Positives = 110/303 (36%), Gaps = 64/303 (21%)

Query: 616 NEVFQESEEEKQPEVPSSLAKGESLSLP-------------------GPSPPPDGTEQVI 656
           NE +Q SE  K+ +    +    S S                       SP PDG+E++ 
Sbjct: 97  NEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIG 156

Query: 657 ISRVDDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLL 716
           +       V+  A+  +       +SE E+G   E       + +        + + + +
Sbjct: 157 LE------VDRRASRSSQSSKEEVNSE-EYGSDHETGSSGSSDEQGNNTENEEEGVEEDV 209

Query: 717 TASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPP 776
               EV  D+    E D +GE    +E EEEEE+E  +         EE E  ER+    
Sbjct: 210 EEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEE---------EEYEQDERDQ--- 257

Query: 777 CPEAHGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEG 836
                 +E G   +  S AS   S                 E+ + T    R G  T+  
Sbjct: 258 ------KEEGNDYDTRSEASDSGS-----------------ESVSFTDGSVRSGSGTDGS 294

Query: 837 DASQQE-GCTLGSDPICLSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVV 895
           D  ++E     G  PI    S  S  +   G +    + ++SV A  ++  +  + ++V+
Sbjct: 295 DEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRA--VRKDQTSKLKYVL 352

Query: 896 EDA 898
           +DA
Sbjct: 353 QDA 355


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 65/255 (25%), Positives = 97/255 (38%), Gaps = 31/255 (12%)

Query: 576 PSESVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLA 635
           P+      + L PP   +  SP    S   P     ++L +   +ES     PE P    
Sbjct: 679 PTSPPPEASRLSPPPEDSPTSPPPEDSPASPPP--EDSLMSLPLEESPLLPLPEEPQLCP 736

Query: 636 KGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGL----PGTCSSELEFGGTLE 691
           + E     GP   P   E  +  R ++P ++P A E         P  C+   E   + +
Sbjct: 737 RSE-----GPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791

Query: 692 DEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKE 751
            E P    P+P     S +     L+     PV   P +      ESH+  ++EE     
Sbjct: 792 AEGP-HLSPQPEELHLSPQTEEPHLS-----PVPEEPCLSPQPE-ESHLSPQSEEPCLSP 844

Query: 752 PSQAAAIHPDNCEESEVSEREAQPP-----CPEAHGEELGGFPEVGSPASPPASGGLT-- 804
             + + + P+  E+  +S R  +PP     CP    EEL  FP  G P+  P  G     
Sbjct: 845 RPEESHLSPE-LEKPPLSPRPEKPPEEPGQCPAP--EELPLFPPPGEPSLSPLLGEPALS 901

Query: 805 ---EEPLGPMEGELP 816
              E PL P+  ELP
Sbjct: 902 EPGEPPLSPLPEELP 916



 Score = 37.4 bits (85), Expect = 0.065
 Identities = 51/189 (26%), Positives = 77/189 (40%), Gaps = 24/189 (12%)

Query: 621  ESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPV-ATEDTAGLPGT 679
            E+E+  +PE P   A   S + P PSP  D         +  P  +P  A +D +GL   
Sbjct: 1074 ETEKVSEPECP---ALEPSATSPLPSPMGD---------LSCPAPSPAPALDDFSGLG-- 1119

Query: 680  CSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPV--MEEDTNGE 737
                 E    L+  +    +PEP    GSL +  K     ++ P + APV  ME     +
Sbjct: 1120 -----EDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLD-PEELAPVTPMEVYPECK 1173

Query: 738  SHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASP 797
                Q +  EE++EP    A  P    +S++    +     +A     G  P +GSP  P
Sbjct: 1174 QTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSP-DP 1232

Query: 798  PASGGLTEE 806
               G L+ E
Sbjct: 1233 EGGGSLSME 1241



 Score = 35.8 bits (81), Expect = 0.19
 Identities = 41/127 (32%), Positives = 50/127 (39%), Gaps = 11/127 (8%)

Query: 692 DEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNG--ESHVPQENEEEEE 749
           +E P    PE    S   +A R L     E+P    P     +    ES +    EE   
Sbjct: 445 EESPLSPPPEESPTSPPPEASR-LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503

Query: 750 KEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPASGGLTEEPLG 809
             P +++   P   EES +S  E  PP P A    L   PE  SP SPP      E PL 
Sbjct: 504 SPPPESSPFSP--LEESPLSPPEESPPSP-ALETPLSPPPEA-SPLSPP----FEESPLS 555

Query: 810 PMEGELP 816
           P   ELP
Sbjct: 556 PPPEELP 562


>gi|6912246 CD3E antigen, epsilon polypeptide associated protein
           [Homo sapiens]
          Length = 510

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 52/192 (27%), Positives = 75/192 (39%), Gaps = 28/192 (14%)

Query: 648 PPDGT---EQVIISRVDDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEP---- 700
           P D T   EQ+    ++D V++P  T+      GT   E E G T+E +   + EP    
Sbjct: 264 PEDKTVKQEQINTEPLEDTVLSP--TKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEA 321

Query: 701 ---EPITASGSLKALRKLLTASVEVPVDSAPVMEE-DTNGESHVPQENEEEEEKEPSQAA 756
               P       K    ++    E      P M+  ++ G +  PQ+   E  K  +QAA
Sbjct: 322 IPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQ--PEGAKPQAQAA 379

Query: 757 AIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPAS----------GGLTEE 806
              P    + E  +     P  E  G EL   P+   P + P S          G    E
Sbjct: 380 LAAPKKKTKKEKQQDATVEPETEVVGPEL---PDDLEPQAAPTSTKKKKKKKERGHTVTE 436

Query: 807 PLGPMEGELPGE 818
           P+ P+E ELPGE
Sbjct: 437 PIQPLEPELPGE 448


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 53/200 (26%), Positives = 72/200 (36%), Gaps = 15/200 (7%)

Query: 731  EEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELG---G 787
            EE+  GE     E EEEE +   +      +  EE E  E E +    E  GEE G   G
Sbjct: 837  EEEGEGEEE-EGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEG 895

Query: 788  FPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLG 847
              E G         G  EE  G  +GE  GE       EG G    EEG+   ++G   G
Sbjct: 896  EEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE-------EGEGEGEEEEGEGEGEDGEGEG 948

Query: 848  SDPICLSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPNPDVLLSH 907
             +     E +   E+EE  G+            E        E +   E+          
Sbjct: 949  EE----EEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGE 1004

Query: 908  KDDVKEGEGGQESFPELPSE 927
             ++  EGEG +E   E+  E
Sbjct: 1005 GEEEGEGEGEEEEEGEVEGE 1024



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 44/151 (29%), Positives = 58/151 (38%), Gaps = 9/151 (5%)

Query: 731 EEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEE---LGG 787
           EE+T G     +E  E E  E  +      +  EE E  E E +    E  GEE    G 
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGK 857

Query: 788 FPEVGSPASPPASG----GLTEEPLGPMEGELPGEACTLTAHEGRG-GKCTEEGDASQQE 842
             E G        G    G  EE  G  EGE  GE       EG G G+   EG+  ++E
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEG-EGEEEEGEGEGEEEGEGEGEEEE 916

Query: 843 GCTLGSDPICLSESQVSEEQEEMGGQSSAAQ 873
           G   G +     E +  EE+ E  G+    +
Sbjct: 917 GEGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 43/152 (28%), Positives = 56/152 (36%), Gaps = 19/152 (12%)

Query: 731  EEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPE 790
            EE+  GE     E E EEE+   +      +   E E  E E +    E  GEE  G  E
Sbjct: 897  EEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE 956

Query: 791  VGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDP 850
                          EE  G  EGE  GE       EG G +   EG+  ++EG   G + 
Sbjct: 957  -------------GEEEEGEGEGEEEGEG-EGEEGEGEGEEEEGEGEGEEEEGEEEGEE- 1001

Query: 851  ICLSESQVSEEQEEMGGQSSAAQATASVNAEE 882
                E +  EE E  G +    +    V  EE
Sbjct: 1002 ----EGEGEEEGEGEGEEEEEGEVEGEVEGEE 1029



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 43/153 (28%), Positives = 62/153 (40%), Gaps = 15/153 (9%)

Query: 732  EDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEV 791
            E+  GE    +E  E E +E  +      +   E E  E E +    E  GEE G   E 
Sbjct: 949  EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008

Query: 792  GSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPI 851
            G        G   EE  G +EGE+ GE       EG   +  EEG+  ++EG   G +  
Sbjct: 1009 G-------EGEGEEEEEGEVEGEVEGEE---GEGEGEEEEGEEEGEEREKEG--EGEEN- 1055

Query: 852  CLSESQVSEEQEEMGGQSSAAQATASVNAEEIK 884
                ++  EE+EE   Q +  +     + EE K
Sbjct: 1056 --RRNREEEEEEEGKYQETGEEENERQDGEEYK 1086



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 41/152 (26%), Positives = 57/152 (37%), Gaps = 25/152 (16%)

Query: 731 EEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPE 790
           +E+  GE    +  +EE E++  + A       EE +  E E +    E  GEE     E
Sbjct: 756 KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEE--TEGRGEEKEEGGE 813

Query: 791 VGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDP 850
           V         GG  EE  G  E E   E       EG G +  EEG+  ++EG       
Sbjct: 814 V--------EGGEVEEGKGEREEE--EEEGEGEEEEGEGEE--EEGEGEEEEG------- 854

Query: 851 ICLSESQVSEEQEEMGGQSSAAQATASVNAEE 882
               E +  EE EE  G+    +       EE
Sbjct: 855 ----EGKGEEEGEEGEGEEEGEEGEGEGEEEE 882



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 38/151 (25%), Positives = 53/151 (35%), Gaps = 5/151 (3%)

Query: 732 EDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEV 791
           E+   E H   E EE + +E  +      +  E  EV E E +    E   EE  G  E 
Sbjct: 728 EEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEV-EGEREKEEGERKKEERAGKEEK 786

Query: 792 GSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPI 851
           G        G   E      E E  GE       EG+G +  EE +   +E    G +  
Sbjct: 787 GEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEE-- 844

Query: 852 CLSESQVSEEQEEMGGQSSAAQATASVNAEE 882
              E +  EE+ E  G+    +       EE
Sbjct: 845 --EEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 86/368 (23%), Positives = 134/368 (36%), Gaps = 53/368 (14%)

Query: 577  SESVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLSNEVF--QESEEEKQPEVPSSL 634
            +ESV +L         ++ + A+ A        G     +EV   QE+EEE QPE     
Sbjct: 1919 TESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDV- 1977

Query: 635  AKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEE 694
               E+L +   +   +G  Q     V+ P                       G   E EE
Sbjct: 1978 ---EALEVEVETQEAEGEAQPESEDVEAPEAE--------------------GEMQEAEE 2014

Query: 695  PAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQ 754
             AQ E + + A    +   +      E          E    E+   +E  +E E E  +
Sbjct: 2015 EAQPESDGVEAQPKSEG-EEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQE 2073

Query: 755  AAA-IHPDNCE-ESEVSEREAQPP-----CPEAHGEELGG----FPEVGSPASPPASGGL 803
            A    HP++ + +++ +E EAQP       PEA GE         PE    A P + G  
Sbjct: 2074 AEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEG-- 2131

Query: 804  TEEPLGPMEGELPGEACTLTAHEGRGGKCTE-EGDASQ--QEGCTLGSDPICLSESQVSE 860
             E P    EGE   E+  + A +  G    E EG  +Q  +E      + +   E++   
Sbjct: 2132 IEAP--EAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEA 2189

Query: 861  EQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPNPDVLLSHKDDVKEGEGGQES 920
            + E  G ++  A+  A    E ++     E     E  P P+ +   +    EGE   ES
Sbjct: 2190 QPESEGIEAPEAEGEAQPELEGVEAPEAEE-----EAQPEPEGV---ETPEAEGEAQPES 2241

Query: 921  FPELPSEE 928
              E   E+
Sbjct: 2242 EGETQGEK 2249



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 55/204 (26%), Positives = 77/204 (37%), Gaps = 23/204 (11%)

Query: 620  QESEEEKQPE---VPSSLAKGESLSLPG-PSPPPDGTEQVIISRVDDPVVNPVATEDTAG 675
            QE+E E QPE   V +  A+GE+    G  +P  +G  Q     ++ P     A  ++ G
Sbjct: 2088 QEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEG 2147

Query: 676  LP-----GTCSSELEFGGTLEDEEPAQEEPEPITA----------SGSLKALRKLLTASV 720
            +      G    E E     E EE AQ E E + A          S  ++A      A  
Sbjct: 2148 VEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQP 2207

Query: 721  EVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEA 780
            E+    AP  EE+   E    +  E E E +P        +     +VS  + Q    E 
Sbjct: 2208 ELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQ---SEE 2264

Query: 781  HGEELGGFPEVGSPASPPASGGLT 804
              E     PE   P  PP+ GG T
Sbjct: 2265 ASESSSPVPE-DRPTPPPSPGGDT 2287



 Score = 37.0 bits (84), Expect = 0.085
 Identities = 67/299 (22%), Positives = 101/299 (33%), Gaps = 45/299 (15%)

Query: 643  PGPSPPPDGTEQVIISRVDDP----VVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQE 698
            PG S   +G E         P    V  P A  D     G    E E     E E  AQ 
Sbjct: 1826 PGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQP 1885

Query: 699  EPEPITASGSLKALR------KLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEP 752
            E E +    +   ++      +   A  E   ++  V   +T GE     E  E +E E 
Sbjct: 1886 ESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE 1945

Query: 753  SQAAAIHPDNCE----ESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPASGGLTEEPL 808
            +   A      E    ES+ +E EAQP   +    E+                   E   
Sbjct: 1946 AAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEV-------------------EVET 1986

Query: 809  GPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPICLSESQVSEEQEEMGGQ 868
               EGE   E+  + A E  G     E +A  +      SD +        EE +E+ G+
Sbjct: 1987 QEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPE------SDGVEAQPKSEGEEAQEVEGE 2040

Query: 869  SSAAQATASVNAEEIKV----ARIHECQWVVEDAPNPDVLLSHKDDVKEGEGGQESFPE 923
            +   +  A   ++ ++         E +  V++A       S   D +E EG  E+ PE
Sbjct: 2041 TQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEG--EAQPE 2097



 Score = 31.6 bits (70), Expect = 3.6
 Identities = 42/196 (21%), Positives = 67/196 (34%), Gaps = 34/196 (17%)

Query: 733  DTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVG 792
            +  G++   +   +    E S  + +     E   +SER         H + L G    G
Sbjct: 1762 EAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAG 1821

Query: 793  SPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPIC 852
                P  S G         EGE   E+  + A E        EGDA + EG         
Sbjct: 1822 GDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEA-------EGDAQEAEG--------- 1865

Query: 853  LSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPNPDVLLSHKDDVK 912
              E+Q   E  E    +  A+  A   +E+++     E +W V+            +  +
Sbjct: 1866 --EAQPESEDVE----APEAEGEAQPESEDVETP---EAEWEVQ---------PESEGAE 1907

Query: 913  EGEGGQESFPELPSEE 928
              E  +E+ PE  S E
Sbjct: 1908 APEAEKEAQPETESVE 1923


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 85/380 (22%), Positives = 122/380 (32%), Gaps = 68/380 (17%)

Query: 591  GSNQASPARRASAILPGVLGSETLSNEV----FQESEEEKQPEVPSSLAKGESLSL---- 642
            GSN+      +    P +   ET    V    F   ++E+  +V  SL      S+    
Sbjct: 733  GSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVP 792

Query: 643  ----PGPSPPPDGTEQVIISRVDDPVVNPVAT-----EDTAGLPGTCSSELEFGGTLEDE 693
                P P PPP G     I+    P  +P        E+    PG           +   
Sbjct: 793  EGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGP 852

Query: 694  ---EPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEK 750
                P Q  PE     G   AL + LT       D     EE+   E    +E EE+ E+
Sbjct: 853  VTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912

Query: 751  EPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEE---------------------LGGFP 789
            E         +  EE E  E E +    E   EE                      GG  
Sbjct: 913  EEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEV 972

Query: 790  EVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSD 849
            E G+P  P     L      P     P         E   G   E  +   +E     + 
Sbjct: 973  EEGAPPPPTLPPALPPPESPPKVQPEP---------EPEPGLLLEVEEPGTEEERGADTA 1023

Query: 850  PICLSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPN-PDVLLSHK 908
            P    E+  S+ + E  G+S AA                   Q +VE+ P+ P  LL  +
Sbjct: 1024 PTLAPEALPSQGEVEREGESPAAGPPP---------------QELVEEEPSAPPTLL--E 1066

Query: 909  DDVKEGEGGQESFPELPSEE 928
            ++ ++G    +  PE P+EE
Sbjct: 1067 EETEDGSDKVQPPPETPAEE 1086


>gi|7662058 tectonin beta-propeller repeat containing 2 [Homo
           sapiens]
          Length = 1411

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 73/287 (25%), Positives = 105/287 (36%), Gaps = 58/287 (20%)

Query: 576 PSESVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLA 635
           P    S++ D    +G ++    ++A   LPG   SET        S    +P   SS  
Sbjct: 355 PEGLTSTVRDGLEMSGCSERVHVQQAEK-LPGATVSETRLRGSSMASSVASEPRSRSSSL 413

Query: 636 K----GESLSLPGPSPPPD---GTEQV-----IISRVD---DPVVNPVATE-------DT 673
                G  L  PG    P+   G++ +      IS  D   + VV P+  +         
Sbjct: 414 NSTDSGSGLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTE 473

Query: 674 AGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEED 733
            G   TC S LE   T   E P  + P+ +     L     +L +SV+     +P  E  
Sbjct: 474 GGSRSTCHSSLE--STPCSEFPG-DSPQSLNTD-LLSMTSSVLGSSVDQLSAESPDQESS 529

Query: 734 TNGESH-VPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEEL--GGFPE 790
            NGE + VPQEN + E     + +   PD+  E +   R   P C  AHG EL  G   +
Sbjct: 530 FNGEVNGVPQENTDPETFNVLEVSGSMPDSLAEED-DIRTEMPHCHHAHGRELLNGARED 588

Query: 791 VGSP---------------------------ASPPASGGLTEEPLGP 810
           VG                             +SP A  G   +P+GP
Sbjct: 589 VGGSDVTGLGDEPCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGP 635


>gi|4559408 colony stimulating factor 2 receptor, beta precursor
           [Homo sapiens]
          Length = 897

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 65/275 (23%), Positives = 93/275 (33%), Gaps = 45/275 (16%)

Query: 565 KHNLFEDNMA--LPSESVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLSNEVFQES 622
           K +LF++  A   P  S+S+ T   PP      S       + P   G   +S    ++ 
Sbjct: 483 KSHLFQNGSAELWPPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDP 542

Query: 623 EEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTCSS 682
           +    P          S  LP   PP              P   P A   T   P   +S
Sbjct: 543 KHVCDPPSGPDTTPAAS-DLPTEQPP-------------SPQPGPPAASHT---PEKQAS 585

Query: 683 ELEFGGTLEDEEPAQE------EPEPITASGSLKA----LRKLLTASVEVPVDSAPVMEE 732
             +F G       ++       +PEP    GS K+      + L       V   P+ + 
Sbjct: 586 SFDFNGPYLGPPHSRSLPDILGQPEPPQEGGSQKSPPPGSLEYLCLPAGGQVQLVPLAQA 645

Query: 733 DTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVG 792
              G++        E E+ PSQ AA  P        S      P P A G  +GG  +  
Sbjct: 646 MGPGQA-------VEVERRPSQGAAGSP--------SLESGGGPAPPALGPRVGGQDQKD 690

Query: 793 SPASPPASGGLTEEPLGPMEGELPGEACTLTAHEG 827
           SP + P S G TE+P G   G +       T + G
Sbjct: 691 SPVAIPMSSGDTEDP-GVASGYVSSADLVFTPNSG 724


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 58/230 (25%), Positives = 87/230 (37%), Gaps = 26/230 (11%)

Query: 612 ETLSNEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGT---------EQVIISRVDD 662
           ET + E   E +     E  +  A  E   L    PP D T         E+        
Sbjct: 447 ETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHA 506

Query: 663 PVVNPVATEDTAGLPGTCSSELEFGGTLE---DEEPAQEEPEPITASGSLKALRKLLTAS 719
            V +P+A E TA      S+E++    +E   DE PA+ +      + + +A  ++ + S
Sbjct: 507 EVQSPLAEETTAE---EASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQSPS 563

Query: 720 VE-VPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCP 778
            + V ++ AP+  +  +GE     E   EE     Q  A    + EE+     E QPP  
Sbjct: 564 AKGVSIEEAPLELQPPSGE-----ETTAEEASAAIQLLAATEASAEEAPA---EVQPPPA 615

Query: 779 EAHGEELGGFPEVGSPA--SPPASGGLTEEPLGPMEGELPGEACTLTAHE 826
           E    E+   P   +PA   PP +     E   P   E P E     A E
Sbjct: 616 EEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE 665



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 68/278 (24%), Positives = 107/278 (38%), Gaps = 28/278 (10%)

Query: 558 KEAAILKKHNLFEDNMALPSESVSSLTDLKPPTGSNQASPARRASAILPGVLGSET--LS 615
           +EA +++     +   A  S SV  L ++ PP+     S    A  + P    S +  L 
Sbjct: 322 EEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELL 381

Query: 616 NEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAG 675
            E+   S ++   EV    A+G     P    PP   E +         V P+  E+   
Sbjct: 382 GEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLAD-------VQPLLPEEA-- 432

Query: 676 LPGTCSSELEFGGTLE---DEEPAQ-EEPEPITASGSLKALRKLLTASVEVPVDS----- 726
            P   + EL+    +E   +E P + + P P   +    +    L A+ E P D      
Sbjct: 433 -PREEARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEA 491

Query: 727 -APVMEEDTNGESHVPQENEEEEEKEPSQAAA-IHPDNCEESEVSEREAQPPCPEAHGEE 784
            +P+ EE +  E+H   ++   EE    +A+A I      E+   E  A+   P +  EE
Sbjct: 492 RSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLS--EE 549

Query: 785 LGGFPEVGSPASPPASGGLTEEPLGPMEGELP-GEACT 821
                      SP A G   EE   P+E + P GE  T
Sbjct: 550 TSAEEAPAEVQSPSAKGVSIEE--APLELQPPSGEETT 585



 Score = 37.0 bits (84), Expect = 0.085
 Identities = 46/211 (21%), Positives = 79/211 (37%), Gaps = 18/211 (8%)

Query: 585 DLKPPTGSNQASPARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLPG 644
           +L+PP+G  + + A  ASA +  +  +E  + E   E +     E P+ +    +   P 
Sbjct: 575 ELQPPSG--EETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 632

Query: 645 PSPPPDGTEQVIISRVDDPVVNPVATEDTAGL--PGTCSSELEFGGTLEDEEPAQEEPEP 702
              PP   E          V  P A E  A +  P    +  E      +E PA+ +  P
Sbjct: 633 EVQPPPAEE------APAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLP 686

Query: 703 ITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEP--SQAAAIHP 760
              +     + + L A    P D  P   E+ + + H P  +    E+ P    +A + P
Sbjct: 687 AEET----PIEETLAAVHSPPADDVPA--EEASVDKHSPPADLLLTEEFPIGEASAEVSP 740

Query: 761 DNCEESEVSEREAQPPCPEAHGEELGGFPEV 791
              E++   E   +    E    ++ G P V
Sbjct: 741 PPSEQTPEDEALVENVSTEFQSPQVAGIPAV 771


>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
          Length = 1790

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 59/246 (23%), Positives = 86/246 (34%), Gaps = 42/246 (17%)

Query: 576  PSESVSSLTDLKPPTGSNQASPARRASAILPGVL----------GSETLSNEVFQES-EE 624
            PSE    +  ++ P  +       + + I P +           G   L  E +Q   EE
Sbjct: 1522 PSEEEEVVVTIEKPPAAEPTYTTWKRARIFPMIFKKVRGLADKRGIVDLEGEEWQRRLEE 1581

Query: 625  EKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTCSSEL 684
            E +  +  +L + E+      S     ++    S  +        TE+ +       SE 
Sbjct: 1582 EDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEEES--ESETPSEE 1639

Query: 685  EFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEE--DTNGESHVPQ 742
            E   T E EE    E E   A  ++   R+             P++EE  +  G    PQ
Sbjct: 1640 EESSTPESEESESTESEGEKARKNIVLARR------------RPMVEEVKEVKGRKEEPQ 1687

Query: 743  ENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCP--EAHGEELGGFPEVGSPASPPAS 800
            E    E+KEP           EE E SE E   P P  E+   E    PE GS  S    
Sbjct: 1688 E----EQKEPKM---------EEEEHSEEEESGPAPVEESTDPEAQDIPEEGSAESASVE 1734

Query: 801  GGLTEE 806
            GG+  E
Sbjct: 1735 GGVESE 1740


>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
           protein [Homo sapiens]
          Length = 1463

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 61/280 (21%), Positives = 103/280 (36%), Gaps = 37/280 (13%)

Query: 620 QESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGT 679
           QE EE+KQ    S+  +G        +P    T             +P++       PG 
Sbjct: 293 QEGEEKKQTSGTSN-TRGSRRKPAMTTPTRRSTRNTRAETASQSQRSPISDNSGCDAPGN 351

Query: 680 CSSELEFGGTLEDEEPAQEEPEPITASGSLK--ALRKLLTASVEVPVDSA---PVMEEDT 734
            +  L    + E E+  ++ P+  +     K   L+K L +SV  P  S+    V EE  
Sbjct: 352 SNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEETA 411

Query: 735 NGESHVPQENEEEEEKEPSQAAAI--HPDNCEESEVSEREAQPPCPEAHGEELGGFPEVG 792
             ++    E E + + + S    +  H +N   + +     Q    E H         VG
Sbjct: 412 ESDTSPVLEKEHQPDVDSSNICTVQTHVENQSANCLKSCNEQIEESEKHTANYDTEERVG 471

Query: 793 SPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGSDPIC 852
           S +S   +     + L  + G                    EEG+  + E   + ++ +C
Sbjct: 472 SSSSESCA-----QDLPVLVG--------------------EEGEVKKLENTGIEANVLC 506

Query: 853 LSESQVSEEQEEMGGQSSAAQATAS-VNAEEIK--VARIH 889
           L ES++SE   E GG     Q   S ++  E+K  V  +H
Sbjct: 507 L-ESEISENILEKGGDPLEKQDQISGLSQSEVKTDVCTVH 545


>gi|74136883 heterogeneous nuclear ribonucleoprotein U isoform a
           [Homo sapiens]
          Length = 825

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 44/167 (26%), Positives = 67/167 (40%), Gaps = 14/167 (8%)

Query: 672 DTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITA-SGSLKALRK---LLTASVEVPVDSA 727
           D+AG  G    +    G  E+EE  +EE E I+A  G    L +      A+   P++  
Sbjct: 65  DSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEE 124

Query: 728 PVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAH--GEEL 785
               ED NG+    QE E+E   E   A        +E+   E++ QPP  +     ++ 
Sbjct: 125 EAASEDENGDDQGFQEGEDELGDEEEGAG-------DENGHGEQQPQPPATQQQQPQQQR 177

Query: 786 GGFPEVGSPASPPAS-GGLTEEPLGPMEGELPGEACTLTAHEGRGGK 831
           G   E    +S P S   +T  P G  +G+            G GG+
Sbjct: 178 GAAKEAAGKSSGPTSLFAVTVAPPGARQGQQQAGGKKKAEGGGGGGR 224


>gi|31543148 hypothetical protein LOC79173 [Homo sapiens]
          Length = 637

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 88/401 (21%), Positives = 141/401 (35%), Gaps = 60/401 (14%)

Query: 549 LLDETLKV-IKEAAILKKHNLFEDNMALPSESVSSLTDLKPPTGSNQAS-PARRASAILP 606
           LL ETL V ++EA  L      + + A P +S  S     P +G +Q   P  R + +  
Sbjct: 146 LLVETLGVPLQEATELGDPT--QADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSA 203

Query: 607 GVLGSETLSNEVFQESEEEKQPEVPSSLAKGE---SLSLPGPSPPPDGTEQVIISRVDDP 663
               S+   +E   +  + +   VP    + E   S+   G  P     ++    R    
Sbjct: 204 SQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSIDSEGEKPDRGAPQEGGAQRTAGA 263

Query: 664 VVNPVATEDTAGLPGTCSSELEFGGT---------LEDEEPAQEEPEPITASGSLKALRK 714
            +     E+  G+P T +S    G           LE    AQ  P+P      +    +
Sbjct: 264 GLPGGPQEEGDGVPCTPASAPTSGPAPGLGPASWCLEPGSVAQGSPDPQQTPSRMGREGE 323

Query: 715 LLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEE--SEVSERE 772
              +S+        V+  D + +    +E   E      QA+AI P +     ++   R 
Sbjct: 324 GTHSSLGCS-SLGMVVIADLSTDPTELEERALEVAGPDGQASAISPASPRRKAADGGHRR 382

Query: 773 AQPPCPEAHGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKC 832
           A P C    GE  G   E G    PP                L G   +L    G G   
Sbjct: 383 ALPGCTSLTGETTGESGEAGQDGKPPGD-------------VLVGPTASLALAPGSGESM 429

Query: 833 TEEGDASQQEGCTLGSDPICLSESQ---VSEEQEEMGGQSSAAQATASVNAEEIKVARIH 889
              GD+      T      C+++ Q    ++E+ E+GGQ+         + E  +V    
Sbjct: 430 MGAGDSGHASPDT----GPCVNQKQEPGPAQEEAELGGQN------LERDLEGFRV---- 475

Query: 890 ECQWVVEDAPNPDVLLSHK---DDVKEGEGGQESFPELPSE 927
                   +P   V+L H+   DD  +  G Q+  P+  SE
Sbjct: 476 --------SPQASVVLEHREIADDPLQEPGAQQGIPDTTSE 508



 Score = 31.2 bits (69), Expect = 4.7
 Identities = 40/167 (23%), Positives = 57/167 (34%), Gaps = 11/167 (6%)

Query: 691 EDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEK 750
           ED        E I  S +     +LL  ++ VP+  A  + + T  +S  P+++ +   +
Sbjct: 122 EDRGSGAFSLETIAESSAQSPGCQLLVETLGVPLQEATELGDPTQADSARPEQSSQSPVQ 181

Query: 751 EPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPASGGLTEE-PLG 809
               +    PD+  +       A     + H  E G           P  GG  E  P  
Sbjct: 182 AVPGSGDSQPDDPPDRGTG-LSASQRASQDHLSEQGADDSKPETDRVPGDGGQKEHLPSI 240

Query: 810 PMEGELPGE------ACTLTAHEGRGGKCTEEGDASQQEGCTLGSDP 850
             EGE P            TA  G  G   EEGD      CT  S P
Sbjct: 241 DSEGEKPDRGAPQEGGAQRTAGAGLPGGPQEEGDGVP---CTPASAP 284


>gi|55741473 HECT, C2 and WW domain containing E3 ubiquitin protein
           ligase 2 [Homo sapiens]
          Length = 1572

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 49/205 (23%), Positives = 85/205 (41%), Gaps = 18/205 (8%)

Query: 590 TGSNQASPARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPP 649
           TG++ AS   R +        SET S +   E  +      PS  A+ ES+S     P  
Sbjct: 582 TGTSDASGGSRRAV-------SETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEG 634

Query: 650 DGTEQVIISRVDDPVVNPVATEDT--AGLPGTCSSELEFGGTLEDEEPA-QEEPEPITAS 706
           +   +   S  ++ V   +++ DT  + L      E     + E+E+ A   EP   T+S
Sbjct: 635 ESDLECADSSCNESVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDGACAAEP---TSS 691

Query: 707 GSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEE-----EEKEPSQAAAIHPD 761
           G  +  ++ +  +  +PV   P  E++  G       ++EE     + +   + AA   +
Sbjct: 692 GPAEGSQESVCTAGSLPVVQVPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAAE 751

Query: 762 NCEESEVSEREAQPPCPEAHGEELG 786
           +  + E S  EAQ  C  A  +E G
Sbjct: 752 SPPQEEGSAGEAQGTCEGATAQEEG 776



 Score = 30.8 bits (68), Expect = 6.1
 Identities = 57/229 (24%), Positives = 82/229 (35%), Gaps = 26/229 (11%)

Query: 667 PVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDS 726
           P + E+  GL     +     G+L  +   ++ P     + + +A      AS E   ++
Sbjct: 479 PSSLEEEGGLIMFSRASRADDGSLTSQTKLEDNPVENEEASTHEA------ASFEDKPEN 532

Query: 727 APVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSE--REAQPPCPEAHGEE 784
            P + E +      P+E E   E +PS A     + C   EV +    A     +A G  
Sbjct: 533 LPELAESSLPAGPAPEEGEGGPEPQPS-ADQGSAELCGSQEVDQPTSGADTGTSDASGGS 591

Query: 785 LGGFPEVGS--PASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQE 842
                E  S    S P+      EP  P   E   EA T       G    E  D+S  E
Sbjct: 592 RRAVSETESLDQGSEPSQVSSETEPSDPARTESVSEAST----RPEGESDLECADSSCNE 647

Query: 843 GCTL---GSDPICLS-------ESQVSEEQEEMGGQSSAAQATASVNAE 881
             T      D  C S       E+     QEE  G + AA+ T+S  AE
Sbjct: 648 SVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDG-ACAAEPTSSGPAE 695


>gi|4502805 chromogranin A precursor [Homo sapiens]
          Length = 457

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 60/247 (24%), Positives = 93/247 (37%), Gaps = 29/247 (11%)

Query: 538 ENVYEEILHQILLDE----TLKVIKEAAIL-KKHNLFEDNMALPSESVSSLTDLKPPT-- 590
           E +   + HQ LL E     L+  KE A   KKH+ FED ++   E+ SS  +LK     
Sbjct: 64  ERILSILRHQNLLKELQDLALQGAKERAHQQKKHSGFEDELSEVLENQSSQAELKEAVEE 123

Query: 591 -----------------GSNQASPARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSS 633
                             S +A+   R  A+   +  S+   N      EEE++ E  ++
Sbjct: 124 PSSKDVMEKREDSKEAEKSGEATDGARPQALPEPMQESKAEGNNQAPGEEEEEEEEATNT 183

Query: 634 LAKGESLSLPGPSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTCSSELEFGGTLEDE 693
                  S   P P  +G  + +   + D      A             E E     E+ 
Sbjct: 184 HPPASLPSQKYPGPQAEGDSEGLSQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEA 243

Query: 694 EPAQEEPEPIT---ASGSLKALRKLLTASVEVPVDSA--PVMEEDTNGESHVPQENEEEE 748
            P +E P  +     S   K +RK  + S  + VD A  P  EE  + E    QE+ +++
Sbjct: 244 VPEEEGPTVVLNPHPSLGYKEIRKGESRSEALAVDGAGKPGAEEAQDPEGKGEQEHSQQK 303

Query: 749 EKEPSQA 755
           E+E   A
Sbjct: 304 EEEEEMA 310



 Score = 34.7 bits (78), Expect = 0.42
 Identities = 47/163 (28%), Positives = 58/163 (35%), Gaps = 35/163 (21%)

Query: 728 PVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEELG- 786
           P+ E    G +  P E EEEEE    +A   HP     S+      + P P+A G+  G 
Sbjct: 157 PMQESKAEGNNQAPGEEEEEEE----EATNTHPPASLPSQ------KYPGPQAEGDSEGL 206

Query: 787 --GF--PEVGSPASPPASGGLTEEPLGPMEGELPGEA--------CTLTAHEGRGGKCTE 834
             G    E G  A P       EE     E E   EA          L  H   G K   
Sbjct: 207 SQGLVDREKGLSAEPGWQAKREEEEEEEEEAEAGEEAVPEEEGPTVVLNPHPSLGYKEIR 266

Query: 835 EG---------DASQQEGCTLGSDPICLSE---SQVSEEQEEM 865
           +G         D + + G     DP    E   SQ  EE+EEM
Sbjct: 267 KGESRSEALAVDGAGKPGAEEAQDPEGKGEQEHSQQKEEEEEM 309


>gi|14141161 heterogeneous nuclear ribonucleoprotein U isoform b
           [Homo sapiens]
          Length = 806

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 41/150 (27%), Positives = 63/150 (42%), Gaps = 14/150 (9%)

Query: 672 DTAGLPGTCSSELEFGGTLEDEEPAQEEPEPITA-SGSLKALRK---LLTASVEVPVDSA 727
           D+AG  G    +    G  E+EE  +EE E I+A  G    L +      A+   P++  
Sbjct: 65  DSAGRSGAGLEQEAAAGGDEEEEEEEEEEEGISALDGDQMELGEENGAAGAADSGPMEEE 124

Query: 728 PVMEEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAH--GEEL 785
               ED NG+    QE E+E   E   A        +E+   E++ QPP  +     ++ 
Sbjct: 125 EAASEDENGDDQGFQEGEDELGDEEEGAG-------DENGHGEQQPQPPATQQQQPQQQR 177

Query: 786 GGFPEVGSPASPPAS-GGLTEEPLGPMEGE 814
           G   E    +S P S   +T  P G  +G+
Sbjct: 178 GAAKEAAGKSSGPTSLFAVTVAPPGARQGQ 207


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 80/356 (22%), Positives = 128/356 (35%), Gaps = 50/356 (14%)

Query: 572  NMALPSESVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLSNEVFQESEE------E 625
            ++ LP++    L  L P     + SP++    +  G         EV  E E+      E
Sbjct: 1113 DVPLPADGPERLA-LSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTE 1171

Query: 626  KQP-EVPSSLAKGESLSLPGPSPPPDG----------TEQVII--SRVDDPVVNPVATED 672
              P E P  L   E+++ P P+    G          T Q     S   D V  P    D
Sbjct: 1172 LPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVD 1231

Query: 673  TAGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVE--VPVDSAPVM 730
            + G    C++ L+ G  L  E   + + EP+    ++  +  +    +    P +S P +
Sbjct: 1232 SPGRTEPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEGLAQVAPSESQPTL 1291

Query: 731  EEDTNGESHVPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPC--PEAHGEELGGF 788
            E     +  VP    +    EP +A  +    C   E S  +  P    P A    L   
Sbjct: 1292 E---MSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAA 1348

Query: 789  PEVGSPASPPASGGLTEEPLGPMEGELPGEACTLTAHEGRGGKCTEEGDASQQEGCTLGS 848
             E+      P+ G    + L  +E     E+  L              + S   G TL S
Sbjct: 1349 AELPQARPLPSPGAAGAQALEKLEA---AESLVL--------------EQSFLHGITLLS 1391

Query: 849  DPICLSESQVSEEQEEMGGQSSAAQATASVNAEEIKVARIHECQWVVEDAPNPDVL 904
            +   ++E ++    +EMGG   A  A  S+  E +  A  H  + V+ D P  D L
Sbjct: 1392 E---IAELELERRSQEMGGAERALVARPSL--ESLLAAGSHMLREVL-DGPVVDPL 1441


>gi|118601081 heterogeneous nuclear ribonucleoprotein U-like 2 [Homo
           sapiens]
          Length = 747

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 50/208 (24%), Positives = 78/208 (37%), Gaps = 32/208 (15%)

Query: 589 PTGSNQASPARRASAILPGVLGSETLSNEVFQESEE----EKQPEVPSSLAKGESLSLPG 644
           P G+ +A P R  +A   G  G E    E  +E EE    ++  E P + A G++     
Sbjct: 53  PGGACKAEP-RPVAASGGGPGGDEEEDEEEEEEDEEALLEDEDEEPPPAQALGQAAQ--- 108

Query: 645 PSPPPDGTEQVIISRVDDPVVNPVATEDTAGLPGTCSSELEFGGTLEDEEPAQEEPEPIT 704
             PPP+  E   +    +P  +    E TAG  G    E +  G  E++EP +   +   
Sbjct: 109 --PPPEPPEAAAMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKREEDEPEERSGDE-- 164

Query: 705 ASGSLKALRKLLTASVEVPVDSAPVME-EDTNGESHVPQENEEE-------EEKEPSQAA 756
                       T   EVP D A   + +D + E   P  ++ E        +++     
Sbjct: 165 ------------TPGSEVPGDKAAEEQGDDQDSEKSKPAGSDGERRGVKRQRDEKDEHGR 212

Query: 757 AIHPDNCEESEVSEREAQPPCPEAHGEE 784
           A +    E      +   PP  EA  EE
Sbjct: 213 AYYEFREEAYHSRSKSPLPPEEEAKDEE 240



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 49/191 (25%), Positives = 68/191 (35%), Gaps = 38/191 (19%)

Query: 687 GGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEEDTNGESHVPQEN-- 744
           GG        + EP P+ ASG                    P  +E+ + E     E   
Sbjct: 48  GGGAGPGGACKAEPRPVAASGG------------------GPGGDEEEDEEEEEEDEEAL 89

Query: 745 --EEEEEKEPSQA---AAIHPDNCEESEVSEREAQPPCPEAHGEELGGFPEVGSPASPPA 799
             +E+EE  P+QA   AA  P    E+   E  A+P   E   E   G        S   
Sbjct: 90  LEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAEATAG--------SGGV 141

Query: 800 SGGLTEEPLGPMEGELPGEAC--TLTAHEGRGGKCTEE--GDASQQEGCTLGSDPICLSE 855
           +GG  E+ LG  E + P E         E  G K  EE   D   ++    GSD      
Sbjct: 142 NGG-EEQGLGKREEDEPEERSGDETPGSEVPGDKAAEEQGDDQDSEKSKPAGSDGERRGV 200

Query: 856 SQVSEEQEEMG 866
            +  +E++E G
Sbjct: 201 KRQRDEKDEHG 211


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,043,747
Number of Sequences: 37866
Number of extensions: 2021048
Number of successful extensions: 10557
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 422
Number of HSP's that attempted gapping in prelim test: 8923
Number of HSP's gapped (non-prelim): 1461
length of query: 928
length of database: 18,247,518
effective HSP length: 112
effective length of query: 816
effective length of database: 14,006,526
effective search space: 11429325216
effective search space used: 11429325216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.