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Search of human proteins with 110815798
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110815798 ovochymase 1 [Homo sapiens]
(1134 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110815798 ovochymase 1 [Homo sapiens] 2325 0.0
gi|148231605 ovochymase 2 [Homo sapiens] 316 9e-86
gi|11415040 matriptase [Homo sapiens] 191 4e-48
gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens] 189 1e-47
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 189 1e-47
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 189 2e-47
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 189 2e-47
gi|40254871 transmembrane protease, serine 11E [Homo sapiens] 187 5e-47
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 182 2e-45
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 182 2e-45
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 180 8e-45
gi|4505881 plasminogen [Homo sapiens] 180 8e-45
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 180 8e-45
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 179 1e-44
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 178 2e-44
gi|223942069 enterokinase precursor [Homo sapiens] 177 7e-44
gi|4506153 prostasin preproprotein [Homo sapiens] 176 1e-43
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 175 2e-43
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 174 6e-43
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 173 7e-43
gi|33695155 hepsin [Homo sapiens] 172 2e-42
gi|4504481 hepsin [Homo sapiens] 172 2e-42
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 171 4e-42
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 171 4e-42
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 171 4e-42
gi|4503137 chymotrypsin-like [Homo sapiens] 169 1e-41
gi|148613878 acrosin precursor [Homo sapiens] 169 2e-41
gi|62526043 chymotrypsin C preproprotein [Homo sapiens] 167 7e-41
gi|58218970 protease, serine, 36 [Homo sapiens] 166 9e-41
gi|15559207 elastase 2A preproprotein [Homo sapiens] 166 2e-40
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 2325 bits (6024), Expect = 0.0
Identities = 1134/1134 (100%), Positives = 1134/1134 (100%)
Query: 1 MGLLASAGLLLLLVIGHPRSLGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPW 60
MGLLASAGLLLLLVIGHPRSLGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPW
Sbjct: 1 MGLLASAGLLLLLVIGHPRSLGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPW 60
Query: 61 QVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIP 120
QVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIP
Sbjct: 61 QVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIP 120
Query: 121 VSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGK 180
VSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGK
Sbjct: 121 VSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGK 180
Query: 181 ISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGP 240
ISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGP
Sbjct: 181 ISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGP 240
Query: 241 LVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNLFTGLD 300
LVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNLFTGLD
Sbjct: 241 LVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNLFTGLD 300
Query: 301 RGQPLSKVGSRYITKALSSVQEVNGSQRGKGILDMEKQVGCDHDYVSLRSSSGVLFNQRS 360
RGQPLSKVGSRYITKALSSVQEVNGSQRGKGILDMEKQVGCDHDYVSLRSSSGVLFNQRS
Sbjct: 301 RGQPLSKVGSRYITKALSSVQEVNGSQRGKGILDMEKQVGCDHDYVSLRSSSGVLFNQRS 360
Query: 361 LMEDDGKQNKRVCGKILPSPLLAETSEAMVPFVSDTEDSGSGFELTVTAVQKSEAGSGCG 420
LMEDDGKQNKRVCGKILPSPLLAETSEAMVPFVSDTEDSGSGFELTVTAVQKSEAGSGCG
Sbjct: 361 LMEDDGKQNKRVCGKILPSPLLAETSEAMVPFVSDTEDSGSGFELTVTAVQKSEAGSGCG 420
Query: 421 SLAILVEEGTNHSAKYPDLYPSNTRCHWFICAPEKHIIKLTFEDFAVKFSPNCIYDAVVI 480
SLAILVEEGTNHSAKYPDLYPSNTRCHWFICAPEKHIIKLTFEDFAVKFSPNCIYDAVVI
Sbjct: 421 SLAILVEEGTNHSAKYPDLYPSNTRCHWFICAPEKHIIKLTFEDFAVKFSPNCIYDAVVI 480
Query: 481 YGDSEEKHKLAKLCGMLTITSIFSSSNMTVIYFKSDGKNRLQGFKARFTILPSESLNKFE 540
YGDSEEKHKLAKLCGMLTITSIFSSSNMTVIYFKSDGKNRLQGFKARFTILPSESLNKFE
Sbjct: 481 YGDSEEKHKLAKLCGMLTITSIFSSSNMTVIYFKSDGKNRLQGFKARFTILPSESLNKFE 540
Query: 541 PKLPPQNNPVSTVKAILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQC 600
PKLPPQNNPVSTVKAILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQC
Sbjct: 541 PKLPPQNNPVSTVKAILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQC 600
Query: 601 GGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLS 660
GGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLS
Sbjct: 601 GGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLS 660
Query: 661 YDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQ 720
YDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQ
Sbjct: 661 YDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQ 720
Query: 721 VHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYG 780
VHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYG
Sbjct: 721 VHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYG 780
Query: 781 IVSWGAGCVQPWKPGVFARVMIFLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSA 840
IVSWGAGCVQPWKPGVFARVMIFLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSA
Sbjct: 781 IVSWGAGCVQPWKPGVFARVMIFLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSA 840
Query: 841 SWPGCCSEAELEKPRGFFPTPRYLLDYRGRLECSWVLRVSASSMAKFTIEYLSLLGSPVC 900
SWPGCCSEAELEKPRGFFPTPRYLLDYRGRLECSWVLRVSASSMAKFTIEYLSLLGSPVC
Sbjct: 841 SWPGCCSEAELEKPRGFFPTPRYLLDYRGRLECSWVLRVSASSMAKFTIEYLSLLGSPVC 900
Query: 901 QDSVLIIYEERHSKRKTAGGLHGRRLYSMTFMSPGPLVRVTFHALVRGAFGISYIVLKVL 960
QDSVLIIYEERHSKRKTAGGLHGRRLYSMTFMSPGPLVRVTFHALVRGAFGISYIVLKVL
Sbjct: 901 QDSVLIIYEERHSKRKTAGGLHGRRLYSMTFMSPGPLVRVTFHALVRGAFGISYIVLKVL 960
Query: 961 GPKDSKITRLSQSSNREHLVPCEDVLLTKPEGIMQIPRNSHRTTMGCQWRLVAPLNHIIQ 1020
GPKDSKITRLSQSSNREHLVPCEDVLLTKPEGIMQIPRNSHRTTMGCQWRLVAPLNHIIQ
Sbjct: 961 GPKDSKITRLSQSSNREHLVPCEDVLLTKPEGIMQIPRNSHRTTMGCQWRLVAPLNHIIQ 1020
Query: 1021 LNIINFPMKPTTFVCHGHLRVYEGFGPGKKLIASFAGTLAMILTKDILKREKLNFINTYI 1080
LNIINFPMKPTTFVCHGHLRVYEGFGPGKKLIASFAGTLAMILTKDILKREKLNFINTYI
Sbjct: 1021 LNIINFPMKPTTFVCHGHLRVYEGFGPGKKLIASFAGTLAMILTKDILKREKLNFINTYI 1080
Query: 1081 MHIWENSVYDNVRSVGKRKQKKFASNLSYSMEAEKSRIQVPADLVPAKGSLSGS 1134
MHIWENSVYDNVRSVGKRKQKKFASNLSYSMEAEKSRIQVPADLVPAKGSLSGS
Sbjct: 1081 MHIWENSVYDNVRSVGKRKQKKFASNLSYSMEAEKSRIQVPADLVPAKGSLSGS 1134
>gi|148231605 ovochymase 2 [Homo sapiens]
Length = 564
Score = 316 bits (809), Expect = 9e-86
Identities = 195/566 (34%), Positives = 296/566 (52%), Gaps = 59/566 (10%)
Query: 3 LLASAGLLLLLVI-----GHPRSLGL----KCGIRMVNMKSKEPAVGSRFFSRISSWRNS 53
L++ L+LLL I G +L L CG +V + +P FSRI
Sbjct: 2 LISRNKLILLLGIVFFERGKSATLSLPKAPSCGQSLVKV---QPWNYFNIFSRILGGSQV 58
Query: 54 TVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKD 113
+PWQVSLK + H CGGS++ V+TAAHC+ + + + VT+GEY L Q D
Sbjct: 59 EKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCI--ANRNIVSTLNVTAGEYDLSQTD 116
Query: 114 KQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILC 173
EQ + + +I HP +++++ M DIALL + +FG+ V PICLP+ ++ E G +C
Sbjct: 117 PGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFIC 176
Query: 174 LSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDAC 233
++GWG++++ S VLQE+ LPI+ C L ++ P G+T LC GFPD G DAC
Sbjct: 177 TTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDAC 236
Query: 234 QGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKA---SLGIFSKVSELMDF 290
QGDSGG L+CR G W LAG+TSW GC G RNN K+ S GIF+ +S+++ +
Sbjct: 237 QGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRG---WRNNVRKSDQGSPGIFTDISKVLPW 293
Query: 291 ITQNLFTGLDRGQPLS-----------KVGSRYITKALSSVQEVNGSQRGKGILDMEKQV 339
I +++ TG R + G + ++L E QR L + +++
Sbjct: 294 IHEHIQTGNRRKSSRAWCSEQDVIVSGAEGKLHFPESLHLYYE--SKQRCVWTLLVPEEM 351
Query: 340 ------------GCDHDYVSLRSSSGVLFNQRSLMEDDGKQNKRVCGKILPSPLLAETSE 387
C H Y+S+ S +ED + + CG+ LPS +L ++
Sbjct: 352 HVLLSFSHLDVESCHHSYLSMYS-----------LED--RPIGKFCGESLPSSILIGSNS 398
Query: 388 AMVPFVSDTEDSGSGFELTVTAVQKSE-AGSGCGSLAILVEEGTNHSAKYPDLYPSNTRC 446
+ FVSD D+ +GF LT A++ + SGC L +L EEG S YP+ Y C
Sbjct: 399 LRLKFVSDATDNAAGFNLTYKALKPNYIPDSGCSYLTVLFEEGLIQSLNYPENYSDKANC 458
Query: 447 HWFICAPEKHIIKLTFEDFAVKFSPNCIYDAVVIYGDSEEKHKLAKLCGMLTITSIFSSS 506
W A + H+IKL+F+ ++ S +C D V ++ D E K ++A+LCG T + S S
Sbjct: 459 DWIFQASKHHLIKLSFQSLEIEESGDCTSDYVTVHSDVERKKEIARLCGYDVPTPVLSPS 518
Query: 507 NMTVIYFKSDGKNRLQGFKARFTILP 532
++ +I F+SD +GF+A + +P
Sbjct: 519 SIMLISFQSDENGTCRGFQATVSFIP 544
Score = 178 bits (452), Expect = 2e-44
Identities = 137/504 (27%), Positives = 222/504 (44%), Gaps = 67/504 (13%)
Query: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDH 633
RI GG + +PWQV L+ + CGG+I++P W++TAAHC+ +N + + AG++
Sbjct: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEY 110
Query: 634 DRNLKESTEQVRRAKHIIVHEDFNTLS-YDSDIALIQLSSPLEYNSVVRPVCLPHSAEPL 692
D + + EQ + +I+H F+T D DIAL++++ ++ V P+CLP E
Sbjct: 111 DLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQF 170
Query: 693 FSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAA 752
+ IC GWG ++ G L+ LQ++ + +L E C + + +C GF
Sbjct: 171 EAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGF-P 229
Query: 753 SGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWK----------PGVFARVMI 802
G +D CQGDSGG L+CR++ G + L G+ SWG GC + W+ PG+F +
Sbjct: 230 DGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISK 289
Query: 803 FLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSASWPGCCSEAEL----EKPRGFF 858
L WI I QT N+ K+ S +W CSE ++ + + F
Sbjct: 290 VLPWIHEHI------QTGNRRKS-------------SRAW---CSEQDVIVSGAEGKLHF 327
Query: 859 PTPRYLLDYRGRLECSWVLRVSASSMAKFTIEYLSLLGSPVCQDSVLIIYEERHSKRKTA 918
P +L Y + C W L V + +L + C S L +Y + +
Sbjct: 328 PESLHLY-YESKQRCVWTLLVPEEMHVLLSFSHLDV---ESCHHSYLSMYS---LEDRPI 380
Query: 919 GGLHGRRLYSMTFMSPGPL-VRVTFHALVRGA-FGISYIVLKVLGPKDSKITRLSQSSNR 976
G G L S + L ++ A A F ++Y LK DS
Sbjct: 381 GKFCGESLPSSILIGSNSLRLKFVSDATDNAAGFNLTYKALKPNYIPDS----------- 429
Query: 977 EHLVPCEDVLLTKPEGIMQ---IPRNSHRTTMGCQWRLVAPLNHIIQLNIINFPMKPTTF 1033
C + + EG++Q P N + C W A +H+I+L+ + ++ +
Sbjct: 430 ----GCSYLTVLFEEGLIQSLNYPEN-YSDKANCDWIFQASKHHLIKLSFQSLEIEESGD 484
Query: 1034 VCHGHLRVYEGFGPGKKLIASFAG 1057
++ V+ KK IA G
Sbjct: 485 CTSDYVTVHSDV-ERKKEIARLCG 507
Score = 41.6 bits (96), Expect = 0.004
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 11/81 (13%)
Query: 333 LDMEKQVGCDHDYVSLRSSSGVLFNQRSLMEDDGKQNKRVCGKILPSPLLAETSEAMVPF 392
L++E+ C DYV++ S + K+ R+CG +P+P+L+ +S ++ F
Sbjct: 477 LEIEESGDCTSDYVTVHSDV-----------ERKKEIARLCGYDVPTPVLSPSSIMLISF 525
Query: 393 VSDTEDSGSGFELTVTAVQKS 413
SD + GF+ TV+ + K+
Sbjct: 526 QSDENGTCRGFQATVSFIPKA 546
>gi|11415040 matriptase [Homo sapiens]
Length = 855
Score = 191 bits (484), Expect = 4e-48
Identities = 105/255 (41%), Positives = 147/255 (57%), Gaps = 15/255 (5%)
Query: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGD-YQCGGAIINPVWILTAAHCVQ- 618
CG+ F+ Q R+ GG +A WPWQV L LG + CG ++I+P W+++AAHC
Sbjct: 604 CGLRSFTRQ---ARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYID 660
Query: 619 ----LKNNPLSWTIIAGDHDRNLKESTE-QVRRAKHIIVHEDFNTLSYDSDIALIQLSSP 673
++P WT G HD++ + + Q RR K II H FN ++D DIAL++L P
Sbjct: 661 DRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDYDIALLELEKP 720
Query: 674 LEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTY 733
EY+S+VRP+CLP ++ + + VTGWG G A LQ+ ++ V+ + CE+
Sbjct: 721 AEYSSMVRPICLPDASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLL 780
Query: 734 YSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWK 793
P IT +M+C GF SG D CQGDSGGPL +G G+VSWG GC Q K
Sbjct: 781 ----PQQITPRMMCVGF-LSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNK 835
Query: 794 PGVFARVMIFLDWIQ 808
PGV+ R+ +F DWI+
Sbjct: 836 PGVYTRLPLFRDWIK 850
Score = 123 bits (308), Expect = 1e-27
Identities = 77/243 (31%), Positives = 122/243 (50%), Gaps = 24/243 (9%)
Query: 59 PWQVSLKS-DEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQ 117
PWQVSL + + H CG SLI + +V+AAHC + ++ + T L D+ ++
Sbjct: 627 PWQVSLHALGQGHICGASLISPNWLVSAAHCY--IDDRGFRYSDPTQWTAFLGLHDQSQR 684
Query: 118 NIP------VSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGI 171
+ P + +II+HP +N + DIALL L+ ++ + V+PICLPD+ G
Sbjct: 685 SAPGVQERRLKRIISHPFFNDFTF-DYDIALLELEKPAEYSSMVRPICLPDASHVFPAGK 743
Query: 172 LCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMD 231
+GWG + +LQ+ E+ +++ C +L P M+C GF G+D
Sbjct: 744 AIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQITP----RMMCVGFLSGGVD 799
Query: 232 ACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFI 291
+CQGDSGGPL G AG+ SW GCA + P G+++++ D+I
Sbjct: 800 SCQGDSGGPLSSVEADGRIFQAGVVSWGDGCAQRNKP----------GVYTRLPLFRDWI 849
Query: 292 TQN 294
+N
Sbjct: 850 KEN 852
Score = 52.8 bits (125), Expect = 2e-06
Identities = 47/165 (28%), Positives = 70/165 (42%), Gaps = 19/165 (11%)
Query: 371 RVCGKILPSPLLAETSEA---MVPFVSDTEDSGSGFELTVTAVQKSEAGSGCGSLAILVE 427
++CG PS L S ++ +++TE GFE T + + S CG +
Sbjct: 292 QLCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRM---SSCGG-RLRKA 347
Query: 428 EGTNHSAKYPDLYPSNTRCHWFICAPEKHIIKLTFEDFAVKF----SPNCIYDAVVIYGD 483
+GT +S YP YP N C W I P +K+ F+ F + + C D V I G+
Sbjct: 348 QGTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVEINGE 407
Query: 484 SEEKHKLAKLCGMLTITSIFSSSNMTVIYFKSDGKNRLQGFKARF 528
K CG + + S+SN + F SD GF A +
Sbjct: 408 --------KYCGERSQFVVTSNSNKITVRFHSDQSYTDTGFLAEY 444
Score = 47.4 bits (111), Expect = 8e-05
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 6/106 (5%)
Query: 436 YPDL-YPSNTRCHWFICAPEKHIIKLTFEDFAVKFSPNCIYDAVVIYG--DSEEKHKLAK 492
+PD YP++ RC W + ++ LTF F + D V +Y E H L +
Sbjct: 233 FPDSPYPAHARCQWALRGDADSVLSLTFRSFDLASCDERGSDLVTVYNTLSPMEPHALVQ 292
Query: 493 LCGMLTIT---SIFSSSNMTVIYFKSDGKNRLQGFKARFTILPSES 535
LCG + + SS N+ +I ++ + R GF+A F LP S
Sbjct: 293 LCGTYPPSYNLTFHSSQNVLLITLITNTERRHPGFEATFFQLPRMS 338
>gi|153791781 transmembrane protease, serine 11E2 [Homo sapiens]
Length = 423
Score = 189 bits (480), Expect = 1e-47
Identities = 106/275 (38%), Positives = 149/275 (54%), Gaps = 12/275 (4%)
Query: 541 PKLPPQNNPVSTVK-----AILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFL 595
PK+ PQ+ + + + L+ CG S RI GG E WPWQ L++
Sbjct: 153 PKVDPQSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWD 212
Query: 596 GDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHED 655
G ++CG +IN W+++AAHC NP WT G +K S + R + IIVHE
Sbjct: 213 GSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGV---TIKPS-KMKRGLRRIIVHEK 268
Query: 656 FNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASR 715
+ S+D DI+L +LSSP+ Y + V VCLP ++ ++ VTG+G++ DG +
Sbjct: 269 YKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNH 328
Query: 716 LQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGP 775
L+Q QV +++ C A+ IT +M+CAG + G+ D CQGDSGGPLV
Sbjct: 329 LRQAQVTLIDATTCNEP--QAYNDAITPRMLCAG-SLEGKTDACQGDSGGPLVSSDARDI 385
Query: 776 FVLYGIVSWGAGCVQPWKPGVFARVMIFLDWIQSK 810
+ L GIVSWG C +P KPGV+ RV DWI SK
Sbjct: 386 WYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK 420
Score = 124 bits (310), Expect = 7e-28
Identities = 81/236 (34%), Positives = 122/236 (51%), Gaps = 23/236 (9%)
Query: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
PWQ SL+ D H CG +LI +V+AAHC + KN + + + K + +
Sbjct: 204 PWQASLQWDGSHRCGATLINATWLVSAAHCFTTY-----KNPARWTASFGVTIKPSKMKR 258
Query: 119 IPVSKIITHPEYN--SREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSS 176
+ +II H +Y S +Y DI+L L V + NAV +CLPD+ + +PG + +
Sbjct: 259 -GLRRIIVHEKYKHPSHDY---DISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVT 314
Query: 177 GWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGD 236
G+G + N L++ ++ ++D CN ++ N + MLCAG + DACQGD
Sbjct: 315 GFGALKNDGYSQNHLRQAQVTLIDATTCNEP-QAYN-DAITPRMLCAGSLEGKTDACQGD 372
Query: 237 SGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFIT 292
SGGPLV IW LAGI SW CA + P G++++V+ L D+IT
Sbjct: 373 SGGPLVSSDARDIWYLAGIVSWGDECAKPNKP----------GVYTRVTALRDWIT 418
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 189 bits (480), Expect = 1e-47
Identities = 110/313 (35%), Positives = 163/313 (52%), Gaps = 20/313 (6%)
Query: 533 SESLNKFEPKLPPQNNPVSTVKAILHDVCGIPPFSPQW-LSRRIAGGEEACPHCWPWQVG 591
S+ + K P+ Q + S H CG+ P W ++ RI GG EA P +PWQ
Sbjct: 164 SQCVTKVNPECDDQED-CSDGSDEAHCECGL---QPAWRMAGRIVGGMEASPGEFPWQAS 219
Query: 592 LRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHII 651
LR ++ CG AIIN W+++AAHC +P W G + E++ + I+
Sbjct: 220 LRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIV 279
Query: 652 VHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGG 711
H +N + D D+A+++L+SPL + ++PVCLP + S+ C ++GWG + D
Sbjct: 280 KHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFL 339
Query: 712 LASR-LQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCR 770
+ LQ+ V +L++ +C Y H +T++M+CAG+ G+ D CQGDSGGPLVC
Sbjct: 340 VKPEVLQKATVELLDQALCASLY--GH--SLTDRMVCAGY-LDGKVDSCQGDSGGPLVCE 394
Query: 771 HENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWIQSKINGPASLQTNNKCKTLKQQL 830
+G F L GIVSWG GC + +PGV+ARV DWI L+ K
Sbjct: 395 EPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWI---------LEATTKASMPLAPT 445
Query: 831 PPPTPSPDSASWP 843
P P+ S +WP
Sbjct: 446 MAPAPAAPSTAWP 458
Score = 179 bits (455), Expect = 1e-44
Identities = 103/294 (35%), Positives = 150/294 (51%), Gaps = 15/294 (5%)
Query: 519 NRLQGFKARFTILPSESLNKFEPKLPPQNNPVSTVKAILHDVCGIPPFSPQWLSRRIAGG 578
+R+ G A T+ + + + P + P +T L D CG+ P + RI GG
Sbjct: 778 SRVTGQPANSTLSAVSTTARGQTPFP--DAPEATTHTQLPD-CGLAPAA----LTRIVGG 830
Query: 579 EEACPHCWPWQVGLRFLG-DYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNL 637
A WPWQV L +++CG ++ W+L+AAHC + +P W G L
Sbjct: 831 SAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPF--L 888
Query: 638 KESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEI 697
+ Q+ R I H +N + D D+AL++L+ P+ + +VRP+CLP A
Sbjct: 889 SGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTR 948
Query: 698 CAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKD 757
C +TGWGS+ G +A +LQ+ V +L + C Y P I+ +M+CAGF G D
Sbjct: 949 CVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFY----PVQISSRMLCAGFPQGG-VD 1003
Query: 758 FCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWIQSKI 811
C GD+GGPL CR +G +VL G+ SWG GC +P PGV+ RV WI I
Sbjct: 1004 SCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHI 1057
Score = 149 bits (375), Expect = 2e-35
Identities = 87/253 (34%), Positives = 128/253 (50%), Gaps = 19/253 (7%)
Query: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHC---- 616
CG P + R+ GG A PWQV L+ + CG ++ W+L+AAHC
Sbjct: 492 CGARPAMEK--PTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHT 549
Query: 617 -VQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLE 675
V+ L + G +K +V ++H +N D D+A+++L+SPL
Sbjct: 550 KVEQVRAHLGTASLLGLGGSPVKIGLRRV------VLHPLYNPGILDFDLAVLELASPLA 603
Query: 676 YNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRL-QQIQVHVLEREVCEHTYY 734
+N ++PVCLP + + C ++GWG+ L Q+ V +++++ C Y
Sbjct: 604 FNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYN 663
Query: 735 SAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKP 794
+ +T++MICAGF G+ D CQGDSGGPL C G F L GIVSWG GC Q KP
Sbjct: 664 FS----LTDRMICAGFL-EGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKP 718
Query: 795 GVFARVMIFLDWI 807
GV+ R+ WI
Sbjct: 719 GVYTRITRLKGWI 731
Score = 140 bits (352), Expect = 9e-33
Identities = 85/253 (33%), Positives = 127/253 (50%), Gaps = 18/253 (7%)
Query: 42 RFFSRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNIT 101
R RI ++ PWQ SL+ ++ HFCG ++I +V+AAHC + + K +
Sbjct: 198 RMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPT-KWVA 256
Query: 102 VTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLP 161
Y L + V +I+ HP YN+ + D+A+L L + FG +QP+CLP
Sbjct: 257 YVGATY-LSGSEASTVRAQVVQIVKHPLYNA-DTADFDVAVLELTSPLPFGRHIQPVCLP 314
Query: 162 DSDDKVEPGILCLSSGWGKISKTSEYS-NVLQEMELPIMDDRACNTVLKSMNLPPLGRTM 220
+ P CL SGWG + + VLQ+ + ++D C S+ L M
Sbjct: 315 AATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALC----ASLYGHSLTDRM 370
Query: 221 LCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGI 280
+CAG+ D +D+CQGDSGGPLVC G + LAGI SW GCA P G+
Sbjct: 371 VCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRP----------GV 420
Query: 281 FSKVSELMDFITQ 293
+++V+ L D+I +
Sbjct: 421 YARVTRLRDWILE 433
Score = 139 bits (349), Expect = 2e-32
Identities = 79/236 (33%), Positives = 126/236 (53%), Gaps = 19/236 (8%)
Query: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
PWQVSLK HFCG +++ + +++AAHC + +Q++ G SL
Sbjct: 516 PWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVR---AHLGTASLLGLGGSPVK 572
Query: 119 IPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGW 178
I + +++ HP YN + D+A+L L + F +QP+CLP + K G C+ SGW
Sbjct: 573 IGLRRVVLHPLYNPG-ILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGW 631
Query: 179 GKISK-TSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDS 237
G + + +LQ+ + I+D + C+ VL + +L M+CAGF + +D+CQGDS
Sbjct: 632 GNTQEGNATKPELLQKASVGIIDQKTCS-VLYNFSLTD---RMICAGFLEGKVDSCQGDS 687
Query: 238 GGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQ 293
GGPL C G++ LAGI SW GCA P G++++++ L +I +
Sbjct: 688 GGPLACEEAPGVFYLAGIVSWGIGCAQVKKP----------GVYTRITRLKGWILE 733
Score = 133 bits (335), Expect = 8e-31
Identities = 79/239 (33%), Positives = 119/239 (49%), Gaps = 22/239 (9%)
Query: 59 PWQVSL-KSDEHHFCGGSLIQEDRVVTAAHCLDSLSE-KQLKNITVTSGEYSLFQKDKQE 116
PWQVSL H CG L+ E +++AAHC D + KQ T F +
Sbjct: 839 PWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTP-----FLSGAEG 893
Query: 117 QNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSS 176
Q V++I HP YN + D+ALL L V+ V+PICLP+ + G C+ +
Sbjct: 894 QLERVARIYKHPFYNLYT-LDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVIT 952
Query: 177 GWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGD 236
GWG + + + LQ+ + ++ ++ C + MLCAGFP G+D+C GD
Sbjct: 953 GWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQ----ISSRMLCAGFPQGGVDSCSGD 1008
Query: 237 SGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNL 295
+GGPL CR G W+L G+TSW GC P G++++V+ + +I Q++
Sbjct: 1009 AGGPLACREPSGRWVLTGVTSWGYGCGRPHFP----------GVYTRVAAVRGWIGQHI 1057
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 189 bits (479), Expect = 2e-47
Identities = 100/237 (42%), Positives = 141/237 (59%), Gaps = 10/237 (4%)
Query: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLK-NNPLSWTIIAGD 632
RI GGE A P WPWQV L + CGG+II P WI+TAAHCV+ NNP WT AG
Sbjct: 292 RIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI 351
Query: 633 HDRNLK--ESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAE 690
++ + QV + +I H ++++ + ++DIAL++L PL +N +V+PVCLP+
Sbjct: 352 LRQSFMFYGAGYQVEK---VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGM 408
Query: 691 PLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGF 750
L ++C ++GWG+ G + L +V ++E + C Y + IT MICAGF
Sbjct: 409 MLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRY--VYDNLITPAMICAGF 466
Query: 751 AASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWI 807
G D CQGDSGGPLV +N + L G SWG+GC + ++PGV+ VM+F DWI
Sbjct: 467 -LQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
Score = 142 bits (358), Expect = 2e-33
Identities = 93/277 (33%), Positives = 140/277 (50%), Gaps = 27/277 (9%)
Query: 21 LGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQED 80
+ L+C VN+ S SRI ++ PWQVSL H CGGS+I +
Sbjct: 274 VSLRCIACGVNLNSSRQ-------SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPE 326
Query: 81 RVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQ--EQNIPVSKIITHPEYNSREYMSP 138
+VTAAHC+ EK L N + + ++ V K+I+HP Y+S+ +
Sbjct: 327 WIVTAAHCV----EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKT-KNN 381
Query: 139 DIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPI 198
DIAL+ L+ + F + V+P+CLP+ ++P LC SGWG + + S VL ++ +
Sbjct: 382 DIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLL 441
Query: 199 MDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSW 258
++ + CN+ NL + M+CAGF +D+CQGDSGGPLV + IW L G TSW
Sbjct: 442 IETQRCNSRYVYDNL--ITPAMICAGFLQGNVDSCQGDSGGPLVTSK-NNIWWLIGDTSW 498
Query: 259 VAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNL 295
+GCA P G++ V D+I + +
Sbjct: 499 GSGCAKAYRP----------GVYGNVMVFTDWIYRQM 525
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 189 bits (479), Expect = 2e-47
Identities = 100/237 (42%), Positives = 141/237 (59%), Gaps = 10/237 (4%)
Query: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLK-NNPLSWTIIAGD 632
RI GGE A P WPWQV L + CGG+II P WI+TAAHCV+ NNP WT AG
Sbjct: 255 RIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI 314
Query: 633 HDRNLK--ESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAE 690
++ + QV + +I H ++++ + ++DIAL++L PL +N +V+PVCLP+
Sbjct: 315 LRQSFMFYGAGYQVEK---VISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGM 371
Query: 691 PLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGF 750
L ++C ++GWG+ G + L +V ++E + C Y + IT MICAGF
Sbjct: 372 MLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRY--VYDNLITPAMICAGF 429
Query: 751 AASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWI 807
G D CQGDSGGPLV +N + L G SWG+GC + ++PGV+ VM+F DWI
Sbjct: 430 -LQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484
Score = 142 bits (358), Expect = 2e-33
Identities = 93/277 (33%), Positives = 140/277 (50%), Gaps = 27/277 (9%)
Query: 21 LGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQED 80
+ L+C VN+ S SRI ++ PWQVSL H CGGS+I +
Sbjct: 237 VSLRCIACGVNLNSSRQ-------SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPE 289
Query: 81 RVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQ--EQNIPVSKIITHPEYNSREYMSP 138
+VTAAHC+ EK L N + + ++ V K+I+HP Y+S+ +
Sbjct: 290 WIVTAAHCV----EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKT-KNN 344
Query: 139 DIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPI 198
DIAL+ L+ + F + V+P+CLP+ ++P LC SGWG + + S VL ++ +
Sbjct: 345 DIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLL 404
Query: 199 MDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSW 258
++ + CN+ NL + M+CAGF +D+CQGDSGGPLV + IW L G TSW
Sbjct: 405 IETQRCNSRYVYDNL--ITPAMICAGFLQGNVDSCQGDSGGPLVTSK-NNIWWLIGDTSW 461
Query: 259 VAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQNL 295
+GCA P G++ V D+I + +
Sbjct: 462 GSGCAKAYRP----------GVYGNVMVFTDWIYRQM 488
>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
Length = 423
Score = 187 bits (475), Expect = 5e-47
Identities = 105/275 (38%), Positives = 148/275 (53%), Gaps = 12/275 (4%)
Query: 541 PKLPPQNNPVSTVK-----AILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFL 595
PK+ P + + + + L+ CG S RI GG E WPWQ L++
Sbjct: 153 PKVDPHSVKIKKINKTETDSYLNHCCGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWD 212
Query: 596 GDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHED 655
G ++CG +IN W+++AAHC NP WT G +K S + R + IIVHE
Sbjct: 213 GSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGV---TIKPS-KMKRGLRRIIVHEK 268
Query: 656 FNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASR 715
+ S+D DI+L +LSSP+ Y + V VCLP ++ ++ VTG+G++ DG +
Sbjct: 269 YKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVTGFGALKNDGYSQNH 328
Query: 716 LQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGP 775
L+Q QV +++ C A+ IT +M+CAG + G+ D CQGDSGGPLV
Sbjct: 329 LRQAQVTLIDATTCNEP--QAYNDAITPRMLCAG-SLEGKTDACQGDSGGPLVSSDARDI 385
Query: 776 FVLYGIVSWGAGCVQPWKPGVFARVMIFLDWIQSK 810
+ L GIVSWG C +P KPGV+ RV DWI SK
Sbjct: 386 WYLAGIVSWGDECAKPNKPGVYTRVTALRDWITSK 420
Score = 124 bits (310), Expect = 7e-28
Identities = 81/236 (34%), Positives = 122/236 (51%), Gaps = 23/236 (9%)
Query: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
PWQ SL+ D H CG +LI +V+AAHC + KN + + + K + +
Sbjct: 204 PWQASLQWDGSHRCGATLINATWLVSAAHCFTTY-----KNPARWTASFGVTIKPSKMKR 258
Query: 119 IPVSKIITHPEYN--SREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSS 176
+ +II H +Y S +Y DI+L L V + NAV +CLPD+ + +PG + +
Sbjct: 259 -GLRRIIVHEKYKHPSHDY---DISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMFVT 314
Query: 177 GWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGD 236
G+G + N L++ ++ ++D CN ++ N + MLCAG + DACQGD
Sbjct: 315 GFGALKNDGYSQNHLRQAQVTLIDATTCNEP-QAYN-DAITPRMLCAGSLEGKTDACQGD 372
Query: 237 SGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFIT 292
SGGPLV IW LAGI SW CA + P G++++V+ L D+IT
Sbjct: 373 SGGPLVSSDARDIWYLAGIVSWGDECAKPNKP----------GVYTRVTALRDWIT 418
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 182 bits (462), Expect = 2e-45
Identities = 113/331 (34%), Positives = 166/331 (50%), Gaps = 15/331 (4%)
Query: 483 DSEEKHKLAKLCGMLTITSIFSSSNMTVIYFKSDGKNRLQGFKARFTILPSESLNKFEPK 542
D + H C L S SS N+ V + + F + +LP + +
Sbjct: 131 DDWKGHYANVACAQLGFPSYVSSDNLRVSSLEGQFREE---FVSIDHLLPDDKVTALHHS 187
Query: 543 LPPQNNPVST-VKAILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCG 601
+ + S V + CG + S RI GG + WPWQ L+F G + CG
Sbjct: 188 VYVREGCASGHVVTLQCTACG----HRRGYSSRIVGGNMSLLSQWPWQASLQFQGYHLCG 243
Query: 602 GAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSY 661
G++I P+WI+TAAHCV P SWTI G +L ++ + I+ H +
Sbjct: 244 GSVITPLWIITAAHCVYDLYLPKSWTIQVG--LVSLLDNPAPSHLVEKIVYHSKYKPKRL 301
Query: 662 DSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASR-LQQIQ 720
+DIAL++L+ PL +N +++PVCLP+S E ++C +GWG+ G AS L
Sbjct: 302 GNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAA 361
Query: 721 VHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYG 780
V ++ ++C H + G I+ M+CAG+ G D CQGDSGGPLVC+ E + L G
Sbjct: 362 VPLISNKICNHR--DVYGGIISPSMLCAGYLTGG-VDSCQGDSGGPLVCQ-ERRLWKLVG 417
Query: 781 IVSWGAGCVQPWKPGVFARVMIFLDWIQSKI 811
S+G GC + KPGV+ RV FLDWI ++
Sbjct: 418 ATSFGIGCAEVNKPGVYTRVTSFLDWIHEQM 448
Score = 144 bits (362), Expect = 6e-34
Identities = 87/254 (34%), Positives = 138/254 (54%), Gaps = 19/254 (7%)
Query: 43 FFSRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITV 102
+ SRI S ++ PWQ SL+ +H CGGS+I ++TAAHC+ L K+ T+
Sbjct: 213 YSSRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLP--KSWTI 270
Query: 103 TSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPD 162
G SL D + V KI+ H +Y + + DIAL+ L + F +QP+CLP+
Sbjct: 271 QVGLVSLL--DNPAPSHLVEKIVYHSKYKPKR-LGNDIALMKLAGPLTFNEMIQPVCLPN 327
Query: 163 SDDKVEPGILCLSSGWGKISK-TSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTML 221
S++ G +C +SGWG + S VL +P++ ++ CN + + + +ML
Sbjct: 328 SEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNH--RDVYGGIISPSML 385
Query: 222 CAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIF 281
CAG+ G+D+CQGDSGGPLVC+ +W L G TS+ GCA + P G++
Sbjct: 386 CAGYLTGGVDSCQGDSGGPLVCQE-RRLWKLVGATSFGIGCAEVNKP----------GVY 434
Query: 282 SKVSELMDFITQNL 295
++V+ +D+I + +
Sbjct: 435 TRVTSFLDWIHEQM 448
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 182 bits (461), Expect = 2e-45
Identities = 94/251 (37%), Positives = 141/251 (56%), Gaps = 9/251 (3%)
Query: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLK 620
CG P +RI GG EA WPWQV LR + CGG++IN +WILTAAHC +
Sbjct: 173 CGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSN 232
Query: 621 NNPLSWTIIAGDHDRNLKESTEQVR-RAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSV 679
+NP W +G + + ++R R ++I++H ++ + ++++DIAL++L + + +
Sbjct: 233 SNPRDWIATSG-----ISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKD 287
Query: 680 VRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPG 739
+ VCLP + + + VTGWG+ G L+Q QV ++ +VC + ++ G
Sbjct: 288 IHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPH--SYNG 345
Query: 740 GITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFAR 799
I M+CAG G D CQGDSGGPLV + + GIVSWG C P KPGV+ R
Sbjct: 346 AILSGMLCAG-VPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTR 404
Query: 800 VMIFLDWIQSK 810
V +LDWI+ +
Sbjct: 405 VTAYLDWIRQQ 415
Score = 130 bits (327), Expect = 7e-30
Identities = 83/235 (35%), Positives = 118/235 (50%), Gaps = 19/235 (8%)
Query: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
PWQVSL+ + H CGGSLI ++TAAHC S S ++ TSG + F K +
Sbjct: 199 PWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNP--RDWIATSGISTTFPKLRMR-- 254
Query: 119 IPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGW 178
V I+ H Y S + + DIAL+ L++ V F + +CLP + + PG +GW
Sbjct: 255 --VRNILIHNNYKSATHEN-DIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGW 311
Query: 179 GKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSG 238
G L++ ++ I+ + CN S N L MLCAG P G+DACQGDSG
Sbjct: 312 GAQEYAGHTVPELRQGQVRIISNDVCNAP-HSYNGAILSG-MLCAGVPQGGVDACQGDSG 369
Query: 239 GPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFITQ 293
GPLV +W + GI SW C P G++++V+ +D+I Q
Sbjct: 370 GPLVQEDSRRLWFIVGIVSWGDQCGLPDKP----------GVYTRVTAYLDWIRQ 414
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 180 bits (456), Expect = 8e-45
Identities = 100/244 (40%), Positives = 146/244 (59%), Gaps = 15/244 (6%)
Query: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCV--QLKNNPLSWTIIAG 631
RI GG + WPWQV L F+G CG ++I+ W+L+AAHC ++P WT G
Sbjct: 479 RIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLG 538
Query: 632 DHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSS--PLEYNSVVRPVCLPHSA 689
+ + + VRR I+VHE +N+ ++D DIAL+QLS P +++P+C+P +
Sbjct: 539 MYVQGNAKFVSPVRR---IVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPTG 595
Query: 690 EPLFSSEICAVTGWG-SISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICA 748
+ + S E C VTGWG AD + LQQ +V ++++ +C TY G IT +M+CA
Sbjct: 596 QRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTY-----GIITSRMLCA 650
Query: 749 GFAASGEKDFCQGDSGGPLVCRHE-NGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWI 807
G SG++D C+GDSGGPL CR + +G ++L GIVSWG G +P PGV+ RV F+ WI
Sbjct: 651 GI-MSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWI 709
Query: 808 QSKI 811
+
Sbjct: 710 HKYV 713
Score = 123 bits (309), Expect = 9e-28
Identities = 82/250 (32%), Positives = 124/250 (49%), Gaps = 23/250 (9%)
Query: 46 RISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSG 105
RI ++ G PWQVSL +CG S+I + +++AAHC +L + T +
Sbjct: 479 RIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHG---NRLSDPTPWTA 535
Query: 106 EYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLK--HKVKFGNAVQPICLPDS 163
++ + + PV +I+ H YNS+ + DIALL L +QPIC+P +
Sbjct: 536 HLGMYVQGNAKFVSPVRRIVVHEYYNSQTF-DYDIALLQLSIAWPETLKQLIQPICIPPT 594
Query: 164 DDKVEPGILCLSSGWGKISKT-SEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLC 222
+V G C +GWG+ + ++ S VLQ+ E+ ++D C + + MLC
Sbjct: 595 GQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYGIIT-----SRMLC 649
Query: 223 AGFPDWGMDACQGDSGGPLVCRR-GGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIF 281
AG DAC+GDSGGPL CRR G WIL GI SW G + P G++
Sbjct: 650 AGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFP----------GVY 699
Query: 282 SKVSELMDFI 291
++VS + +I
Sbjct: 700 TRVSNFVPWI 709
Score = 43.9 bits (102), Expect = 9e-04
Identities = 25/92 (27%), Positives = 50/92 (54%), Gaps = 4/92 (4%)
Query: 446 CHWFICAPEKHIIKLTFEDFAVKFSPNCIYDAVVIYGD--SEEKHKLAKLCGML-TITSI 502
CH+ + A ++I+L+ + ++ + NC+ D++ IY L ++C T+ S
Sbjct: 147 CHFKLVAIVGYLIRLSIKSIQIE-ADNCVTDSLTIYDSLLPIRSSILYRICEPTRTLMSF 205
Query: 503 FSSSNMTVIYFKSDGKNRLQGFKARFTILPSE 534
S++N+ ++ FKS RL G +A F ++P +
Sbjct: 206 VSTNNLMLVTFKSPHIRRLSGIRAYFEVIPEQ 237
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 180 bits (456), Expect = 8e-45
Identities = 100/250 (40%), Positives = 135/250 (54%), Gaps = 14/250 (5%)
Query: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRF-LGDYQCGGAIINPVWILTAAHCVQL 619
CG P P+ R+ GG A PH WPWQV LR G + CGG +I+P W+LTAAHC++
Sbjct: 567 CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEK 626
Query: 620 KNNPLSWTIIAGDHDR-NLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNS 678
P S+ +I G H NL+ +++ ++ + DIAL++LSSP
Sbjct: 627 SPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPTR-------KDIALLKLSSPAVITD 679
Query: 679 VVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHP 738
V P CLP + C +TGWG G A L++ Q+ V+E +VC Y
Sbjct: 680 KVIPACLPSPNYVVADRTECFITGWGETQGTFG-AGLLKEAQLPVIENKVCNR--YEFLN 736
Query: 739 GGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFA 798
G + +CAG A G D CQGDSGGPLVC E ++L G+ SWG GC +P KPGV+
Sbjct: 737 GRVQSTELCAGHLAGGT-DSCQGDSGGPLVC-FEKDKYILQGVTSWGLGCARPNKPGVYV 794
Query: 799 RVMIFLDWIQ 808
RV F+ WI+
Sbjct: 795 RVSRFVTWIE 804
Score = 121 bits (304), Expect = 3e-27
Identities = 85/237 (35%), Positives = 121/237 (51%), Gaps = 30/237 (12%)
Query: 59 PWQVSLKSD-EHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQ 117
PWQVSL++ HFCGG+LI + V+TAAHCL+ + + V G + + Q
Sbjct: 593 PWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEK--SPRPSSYKVILGAHQEVNLEPHVQ 650
Query: 118 NIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSG 177
I VS++ P DIALL L + V P CLP + V C +G
Sbjct: 651 EIEVSRLFLEPTRK-------DIALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITG 703
Query: 178 WGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGR---TMLCAGFPDWGMDACQ 234
WG+ T + +L+E +LP+++++ CN + +N GR T LCAG G D+CQ
Sbjct: 704 WGETQGTFG-AGLLKEAQLPVIENKVCNRY-EFLN----GRVQSTELCAGHLAGGTDSCQ 757
Query: 235 GDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELMDFI 291
GDSGGPLVC +IL G+TSW GCA + P G++ +VS + +I
Sbjct: 758 GDSGGPLVCFEKDK-YILQGVTSWGLGCARPNKP----------GVYVRVSRFVTWI 803
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 180 bits (456), Expect = 8e-45
Identities = 89/255 (34%), Positives = 143/255 (56%), Gaps = 7/255 (2%)
Query: 556 ILHDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAH 615
+ ++ CG + +I G+ + WPWQ +++ G + CG ++I+ W+L+AAH
Sbjct: 166 LTNNCCGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAH 225
Query: 616 CVQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLE 675
C KNN WT+ G + R+ ++II HE++++ DIAL+QL+ +
Sbjct: 226 CFAKKNNSKDWTVNFGI----VVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVS 281
Query: 676 YNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYS 735
+ +R +CLP + L ++ VTGWG++ +G LQ+ + +++ ++C +Y
Sbjct: 282 FTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASY-- 339
Query: 736 AHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPG 795
A+ G +T+ M+CAGF SGE D CQ DSGGPL + L GIVSWG GC + KPG
Sbjct: 340 AYSGFVTDTMLCAGF-MSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPG 398
Query: 796 VFARVMIFLDWIQSK 810
V+ RV + +WI SK
Sbjct: 399 VYTRVTSYRNWITSK 413
Score = 127 bits (318), Expect = 8e-29
Identities = 84/255 (32%), Positives = 124/255 (48%), Gaps = 21/255 (8%)
Query: 45 SRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTS 104
++I + ++S PWQ S++ H+CG SLI +++AAHC + K+ TV
Sbjct: 183 NKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCF--AKKNNSKDWTVNF 240
Query: 105 GEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSD 164
G +K V II H Y+S + DIAL+ L +V F ++ ICLP++
Sbjct: 241 G----IVVNKPYMTRKVQNIIFHENYSSPG-LHDDIALVQLAEEVSFTEYIRKICLPEAK 295
Query: 165 DKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAG 224
K+ + +GWG + + +LQE L I+D++ CN + TMLCAG
Sbjct: 296 MKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAYSGF--VTDTMLCAG 353
Query: 225 FPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKV 284
F DACQ DSGGPL IW L GI SW GC + P G++++V
Sbjct: 354 FMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKP----------GVYTRV 403
Query: 285 SELMDFITQNLFTGL 299
+ ++IT TGL
Sbjct: 404 TSYRNWITSK--TGL 416
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 179 bits (455), Expect = 1e-44
Identities = 94/256 (36%), Positives = 145/256 (56%), Gaps = 12/256 (4%)
Query: 558 HDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCV 617
H CG+ Q S RI GG + WPWQ L+ G + CGGA+I W++TAAHC
Sbjct: 565 HCDCGL-----QGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCF 619
Query: 618 QLKN--NPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLE 675
Q + + + WT+ G +N + E + +++H S+D D+AL+QL P+
Sbjct: 620 QEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVV 679
Query: 676 YNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYS 735
++ VRPVCLP + C +TGWG++ G +++ LQ++ V ++ +++C Y
Sbjct: 680 RSAAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRY 739
Query: 736 AHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPG 795
+T +M+CAG+ G+KD CQGDSGGPLVC+ +G + L G+VSWG GC +P G
Sbjct: 740 Q----VTPRMLCAGYR-KGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFG 794
Query: 796 VFARVMIFLDWIQSKI 811
V+ R+ + WIQ +
Sbjct: 795 VYTRITGVISWIQQVV 810
Score = 154 bits (388), Expect = 6e-37
Identities = 90/249 (36%), Positives = 131/249 (52%), Gaps = 15/249 (6%)
Query: 45 SRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTS 104
SRI S+ PWQ SL+ H CGG+LI + V+TAAHC S TV
Sbjct: 575 SRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFL 634
Query: 105 GEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSD 164
G+ + E + VS+++ HP Y+ + D+ALL L H V AV+P+CLP
Sbjct: 635 GKVWQNSRWPGEVSFKVSRLLLHP-YHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARS 693
Query: 165 DKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAG 224
EPG+ C +GWG + + SN LQ++++ ++ C+ V + P MLCAG
Sbjct: 694 HFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVTP----RMLCAG 749
Query: 225 FPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKV 284
+ DACQGDSGGPLVC+ G W LAG+ SW GC R N+ G+++++
Sbjct: 750 YRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCG------RPNY----FGVYTRI 799
Query: 285 SELMDFITQ 293
+ ++ +I Q
Sbjct: 800 TGVISWIQQ 808
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 178 bits (452), Expect = 2e-44
Identities = 101/249 (40%), Positives = 130/249 (52%), Gaps = 21/249 (8%)
Query: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRF-LGDYQCGGAIINPVWILTAAHCVQL 619
CG P P+ I GG A PH WPWQV LR G + CGG +I+P W+LTAAHC++
Sbjct: 1806 CGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKK 1865
Query: 620 KNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSV 679
+ P S+ +I G H ES Q + + +DIAL++LS P
Sbjct: 1866 SSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPT------QADIALLKLSRPAVITDK 1919
Query: 680 VRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPG 739
V P CLP + + C +TGWG G L++ Q+ V+E EVC H Y
Sbjct: 1920 VMPACLPSPDYMVTARTECYITGWGETQGTFG-TGLLKEAQLLVIENEVCNHYKY----- 1973
Query: 740 GITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFAR 799
ICA A G D CQGDSGGPLVC E ++L G+ SWG GC +P KPGV+AR
Sbjct: 1974 ------ICAEHLARGT-DSCQGDSGGPLVC-FEKDKYILQGVTSWGLGCARPNKPGVYAR 2025
Query: 800 VMIFLDWIQ 808
V F+ WI+
Sbjct: 2026 VSRFVTWIE 2034
Score = 117 bits (293), Expect = 6e-26
Identities = 87/273 (31%), Positives = 122/273 (44%), Gaps = 41/273 (15%)
Query: 20 SLGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPWQVSLKSD-EHHFCGGSLIQ 78
S CG V K ++ + SW PWQVSL++ HFCGG+LI
Sbjct: 1801 SSSFDCGKPQVEPKKCPGSIVGGCVAHPHSW--------PWQVSLRTRFGKHFCGGTLIS 1852
Query: 79 EDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSP 138
+ V+TAAHCL S + V G + + Q I VS++ P
Sbjct: 1853 PEWVLTAAHCLKKSSRP--SSYKVILGAHQEVNLESHVQEIEVSRLFLEP-------TQA 1903
Query: 139 DIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPI 198
DIALL L + V P CLP D V C +GWG+ T + +L+E +L +
Sbjct: 1904 DIALLKLSRPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTFG-TGLLKEAQLLV 1962
Query: 199 MDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSW 258
+++ CN +CA G D+CQGDSGGPLVC +IL G+TSW
Sbjct: 1963 IENEVCNHY-----------KYICAEHLARGTDSCQGDSGGPLVCFEKDK-YILQGVTSW 2010
Query: 259 VAGCAGGSVPVRNNHVKASLGIFSKVSELMDFI 291
GCA + P G++++VS + +I
Sbjct: 2011 GLGCARPNKP----------GVYARVSRFVTWI 2033
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 177 bits (448), Expect = 7e-44
Identities = 96/254 (37%), Positives = 142/254 (55%), Gaps = 8/254 (3%)
Query: 558 HDVCGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCV 617
H CG + Q ++ +I GG A WPW VGL + G CG ++++ W+++AAHCV
Sbjct: 769 HKSCG-KKLAAQDITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCV 827
Query: 618 QLKN-NPLSWTIIAGDHDRNLKESTEQVRRA-KHIIVHEDFNTLSYDSDIALIQLSSPLE 675
+N P WT I G H ++ S + V R I+++ +N D+DIA++ L +
Sbjct: 828 YGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVN 887
Query: 676 YNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYS 735
Y ++P+CLP + C++ GWG++ G A+ LQ+ V +L E C+
Sbjct: 888 YTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPE 947
Query: 736 AHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPG 795
+ ITE MICAG+ G D CQGDSGGPL+C+ EN + L G+ S+G C P +PG
Sbjct: 948 YN---ITENMICAGYEEGG-IDSCQGDSGGPLMCQ-ENNRWFLAGVTSFGYKCALPNRPG 1002
Query: 796 VFARVMIFLDWIQS 809
V+ARV F +WIQS
Sbjct: 1003 VYARVSRFTEWIQS 1016
Score = 139 bits (350), Expect = 2e-32
Identities = 80/250 (32%), Positives = 130/250 (52%), Gaps = 23/250 (9%)
Query: 46 RISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSG 105
+I N+ PW V L CG SL+ D +V+AAHC+ + + K +
Sbjct: 784 KIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILG- 842
Query: 106 EYSLFQKDK--QEQNIP--VSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLP 161
L K Q +P + +I+ +P YN R DIA+++L+ KV + + +QPICLP
Sbjct: 843 ---LHMKSNLTSPQTVPRLIDEIVINPHYNRRR-KDNDIAMMHLEFKVNYTDYIQPICLP 898
Query: 162 DSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTML 221
+ + PG C +GWG + +N+LQE ++P++ + C + N+ M+
Sbjct: 899 EENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNIT---ENMI 955
Query: 222 CAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIF 281
CAG+ + G+D+CQGDSGGPL+C+ W LAG+TS+ CA + P G++
Sbjct: 956 CAGYEEGGIDSCQGDSGGPLMCQENNR-WFLAGVTSFGYKCALPNRP----------GVY 1004
Query: 282 SKVSELMDFI 291
++VS ++I
Sbjct: 1005 ARVSRFTEWI 1014
Score = 45.8 bits (107), Expect = 2e-04
Identities = 41/129 (31%), Positives = 62/129 (48%), Gaps = 8/129 (6%)
Query: 404 ELTVTAVQKSEAGSGCGSLAILVEEGTNHSA-KYPDLYPSNTRCHWFICAPEKHIIKLTF 462
E T+ E + CG L E T S+ +P+ YP+ C W + A + I+L F
Sbjct: 509 EPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHF 568
Query: 463 EDFAVKFSPNCIYDAVVIY-GDSEEKHKLAKLCGMLTITSIFSSSN-MTVIYFKSDGKNR 520
++F ++ I D V I G+ + LA G + +FS++N MTV+ +D R
Sbjct: 569 QEFDLE----NINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLAR 624
Query: 521 LQGFKARFT 529
GFKA FT
Sbjct: 625 -GGFKANFT 632
Score = 37.7 bits (86), Expect = 0.062
Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 6/122 (4%)
Query: 420 GSLAILVEEGTNHSAKYPDLYPSNTRCHWFICAPEKHIIKLTFEDFAVKFSPNCIYDAVV 479
G + G+ + YP ++ C W I + IKL+F+DF ++ D +
Sbjct: 227 GRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYT-----DILD 281
Query: 480 IY-GDSEEKHKLAKLCGMLTITSIFSSSNMTVIYFKSDGKNRLQGFKARFTILPSESLNK 538
IY G K A + T S+ +T + ++ GF A +T S LN
Sbjct: 282 IYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNN 341
Query: 539 FE 540
+E
Sbjct: 342 YE 343
Score = 31.2 bits (69), Expect = 5.8
Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 11/98 (11%)
Query: 999 NSHRTTMGCQWRLVAPLNHIIQLNIINFPMKPTTFVCHGH---------LRVYEGFGPGK 1049
NS+ C W L A IQL+ F ++ V L VY G GP K
Sbjct: 544 NSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVK 603
Query: 1050 KLIASFAGTLAMILTKDILKRE--KLNFINTYIMHIWE 1085
+ ++ +++T D+L R K NF Y + I E
Sbjct: 604 DVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPE 641
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 176 bits (446), Expect = 1e-43
Identities = 95/257 (36%), Positives = 137/257 (53%), Gaps = 14/257 (5%)
Query: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLK 620
CG+ P RI GG A WPWQV + + G + CGG++++ W+L+AAHC +
Sbjct: 37 CGVAP------QARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSE 90
Query: 621 NNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVV 680
++ ++ + G H + +V K II H + DIAL+QLS P+ ++ +
Sbjct: 91 HHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSRYI 150
Query: 681 RPVCLPHSAEPLFSSEICAVTGWGSISADGGLAS--RLQQIQVHVLEREVCEHTY----Y 734
RP+CLP + + C VTGWG ++ L + LQQ++V ++ RE C Y
Sbjct: 151 RPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAK 210
Query: 735 SAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKP 794
P + E M+CAG+ G KD CQGDSGGPL C E G + L GIVSWG C +P
Sbjct: 211 PEEPHFVQEDMVCAGYVEGG-KDACQGDSGGPLSCPVE-GLWYLTGIVSWGDACGARNRP 268
Query: 795 GVFARVMIFLDWIQSKI 811
GV+ + WIQSK+
Sbjct: 269 GVYTLASSYASWIQSKV 285
Score = 140 bits (353), Expect = 7e-33
Identities = 86/251 (34%), Positives = 131/251 (52%), Gaps = 13/251 (5%)
Query: 45 SRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTS 104
+RI+ ++ PWQVS+ + H CGGSL+ E V++AAHC S K+ + + +
Sbjct: 43 ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA 102
Query: 105 GEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSD 164
+ + +D + + II HP Y +E DIALL L + F ++PICLP ++
Sbjct: 103 HQLDSYSEDAKVSTL--KDIIPHPSY-LQEGSQGDIALLQLSRPITFSRYIRPICLPAAN 159
Query: 165 DKVEPGILCLSSGWGKISKTSEY--SNVLQEMELPIMDDRACNTVLKSMNLPP-----LG 217
G+ C +GWG ++ + LQ++E+P++ CN L +++ P +
Sbjct: 160 ASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCN-CLYNIDAKPEEPHFVQ 218
Query: 218 RTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVP-VRNNHVKA 276
M+CAG+ + G DACQGDSGGPL C G+W L GI SW C + P V
Sbjct: 219 EDMVCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGARNRPGVYTLASSY 277
Query: 277 SLGIFSKVSEL 287
+ I SKV+EL
Sbjct: 278 ASWIQSKVTEL 288
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 175 bits (444), Expect = 2e-43
Identities = 99/256 (38%), Positives = 142/256 (55%), Gaps = 15/256 (5%)
Query: 572 SRRIAGGEEACPHCWPWQVGLRFLGDYQ---CGGAIINPVWILTAAHCVQLKNNPLSWTI 628
S RI GG + WPWQV L+ Q CGG++I W+LTAAHC W I
Sbjct: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447
Query: 629 IAGDHDRNLKESTEQV--RRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLP 686
+G NL + T+ + K II+H+++ + DIALI+L +PL Y +P+CLP
Sbjct: 448 YSGI--LNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP 505
Query: 687 HSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMI 746
+ C VTGWG G + + LQ++ + ++ E C+ Y IT++M+
Sbjct: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK---ITQRMV 562
Query: 747 CAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDW 806
CAG+ G KD C+GDSGGPLVC+H NG + L GI SWG GC + +PGV+ +V ++DW
Sbjct: 563 CAGYKEGG-KDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620
Query: 807 IQSKI---NGPASLQT 819
I K +G A +Q+
Sbjct: 621 ILEKTQSSDGKAQMQS 636
Score = 151 bits (381), Expect = 4e-36
Identities = 92/252 (36%), Positives = 133/252 (52%), Gaps = 20/252 (7%)
Query: 45 SRISSWRNSTVTGHPWQVSLK---SDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNIT 101
+RI NS+ PWQVSL+ + + H CGGSLI V+TAAHC D L + + I
Sbjct: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 448
Query: 102 VTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLP 161
SG +L K + +II H Y E + DIAL+ L+ + + +PICLP
Sbjct: 449 --SGILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLP 505
Query: 162 DSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTML 221
D C +GWG + E N+LQ++ +P++ + C + + + M+
Sbjct: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKIT---QRMV 562
Query: 222 CAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIF 281
CAG+ + G DAC+GDSGGPLVC+ G+W L GITSW GCA P G++
Sbjct: 563 CAGYKEGGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQP----------GVY 611
Query: 282 SKVSELMDFITQ 293
+KV+E MD+I +
Sbjct: 612 TKVAEYMDWILE 623
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 174 bits (440), Expect = 6e-43
Identities = 100/247 (40%), Positives = 140/247 (56%), Gaps = 24/247 (9%)
Query: 575 IAGGEEACPHCWPWQVGLRFLGDYQ---CGGAIINPVWILTAAHCVQLKNNPLSWTIIAG 631
I GG+EA WPWQV LR G Y CGG++I+P W+LTAAHCV L+ +
Sbjct: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV-- 88
Query: 632 DHDRNLKES----TEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPH 687
L+E +Q+ IIVH F T +DIAL++L P+ +S V V LP
Sbjct: 89 ----QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144
Query: 688 SAEPLFSSEICAVTGWGSISADGGLAS--RLQQIQVHVLEREVCEHTYY-SAHPGG---- 740
++E C VTGWG + D L L+Q++V ++E +C+ Y+ A+ G
Sbjct: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204
Query: 741 ITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARV 800
+ + M+CAG + +D CQGDSGGPLVC+ NG ++ G+VSWG GC QP +PG++ RV
Sbjct: 205 VRDDMLCAG---NTRRDSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260
Query: 801 MIFLDWI 807
+LDWI
Sbjct: 261 TYYLDWI 267
Score = 134 bits (338), Expect = 4e-31
Identities = 87/243 (35%), Positives = 131/243 (53%), Gaps = 28/243 (11%)
Query: 59 PWQVSLKSDEH---HFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQ 115
PWQVSL+ HFCGGSLI V+TAAHC+ K L + V E L+ +D
Sbjct: 43 PWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGP-DVKDLAALRVQLREQHLYYQD-- 99
Query: 116 EQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLS 175
Q +PVS+II HP++ + + + DIALL L+ V + V + LP + + PG+ C
Sbjct: 100 -QLLPVSRIIVHPQFYTAQ-IGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWV 157
Query: 176 SGWGKISKTSEYSN--VLQEMELPIMDDRACNT-----VLKSMNLPPLGRTMLCAGFPDW 228
+GWG + L+++++PIM++ C+ ++ + MLCAG +
Sbjct: 158 TGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NT 215
Query: 229 GMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELM 288
D+CQGDSGGPLVC + G W+ AG+ SW GCA + P GI+++V+ +
Sbjct: 216 RRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCAQPNRP----------GIYTRVTYYL 264
Query: 289 DFI 291
D+I
Sbjct: 265 DWI 267
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 173 bits (439), Expect = 7e-43
Identities = 105/286 (36%), Positives = 159/286 (55%), Gaps = 18/286 (6%)
Query: 533 SESLNKFEPKLPPQNNPVSTVKAILHDVCGI-------PPFSPQWLSRRIAGGEEACPHC 585
S ++NK +L P ++ ++ +L+ CGI P + R + G E A
Sbjct: 160 SLTINKPSFRLTPIDS--KKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGE 217
Query: 586 WPWQVGLRFLGD-YQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQV 644
WPWQ L+ +G +QCG ++I+ W+LTAAHC +P W G
Sbjct: 218 WPWQASLQLIGSGHQCGASLISNTWLLTAAHCFWKNKDPTQWIATFGA----TITPPAVK 273
Query: 645 RRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWG 704
R + II+HE+++ + ++DIAL+QLS+ +E++++V+ VCLP S+ L VTG+G
Sbjct: 274 RNVRKIILHENYHRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFG 333
Query: 705 SISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSG 764
SI DG + + L+Q +V + +VC + G IT M+CAGF G+ D C+GDSG
Sbjct: 334 SIVDDGPIQNTLRQARVETISTDVCNRK--DVYDGLITPGMLCAGF-MEGKIDACKGDSG 390
Query: 765 GPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWIQSK 810
GPLV + + +++ GIVSWG C P KPGV+ RV + DWI SK
Sbjct: 391 GPLVYDNHDIWYIV-GIVSWGQSCALPKKPGVYTRVTKYRDWIASK 435
Score = 126 bits (317), Expect = 1e-28
Identities = 96/273 (35%), Positives = 128/273 (46%), Gaps = 24/273 (8%)
Query: 21 LGLKCGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGH-PWQVSLKS-DEHHFCGGSLIQ 78
L +CGIRM + PA S RI R + + G PWQ SL+ H CG SLI
Sbjct: 182 LNSRCGIRMTSSNMPLPASSST--QRIVQGRETAMEGEWPWQASLQLIGSGHQCGASLIS 239
Query: 79 EDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSP 138
++TAAHC K T G K+ V KII H Y+ RE
Sbjct: 240 NTWLLTAAHCF--WKNKDPTQWIATFGATITPPAVKRN----VRKIILHENYH-RETNEN 292
Query: 139 DIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPI 198
DIAL+ L V+F N VQ +CLPDS K+ P +G+G I N L++ +
Sbjct: 293 DIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVET 352
Query: 199 MDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSW 258
+ CN K + + MLCAGF + +DAC+GDSGGPLV IW + GI SW
Sbjct: 353 ISTDVCNR--KDVYDGLITPGMLCAGFMEGKIDACKGDSGGPLV-YDNHDIWYIVGIVSW 409
Query: 259 VAGCAGGSVPVRNNHVKASLGIFSKVSELMDFI 291
CA P G++++V++ D+I
Sbjct: 410 GQSCALPKKP----------GVYTRVTKYRDWI 432
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 172 bits (436), Expect = 2e-42
Identities = 96/242 (39%), Positives = 130/242 (53%), Gaps = 11/242 (4%)
Query: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLS-WTIIAGD 632
RI GG + WPWQV LR+ G + CGG++++ W+LTAAHC +N LS W + AG
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA 221
Query: 633 ----HDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHS 688
L+ + V + D N+ +DIAL+ LSSPL ++PVCLP +
Sbjct: 222 VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAA 281
Query: 689 AEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICA 748
+ L +IC VTGWG+ G A LQ+ +V ++ +VC + + I KM CA
Sbjct: 282 GQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADF--YGNQIKPKMFCA 339
Query: 749 GFAASGEKDFCQGDSGGPLVCR---HENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLD 805
G+ G D CQGDSGGP VC + L GIVSWG GC KPGV+ +V F +
Sbjct: 340 GYPEGG-IDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE 398
Query: 806 WI 807
WI
Sbjct: 399 WI 400
Score = 147 bits (370), Expect = 7e-35
Identities = 93/261 (35%), Positives = 133/261 (50%), Gaps = 25/261 (9%)
Query: 46 RISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSG 105
RI R++++ PWQVSL+ D H CGGSL+ D V+TAAHC + + L V +G
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN-RVLSRWRVFAG 220
Query: 106 EYSLFQKDKQEQNIPVSKIITHPEY------NSREYMSPDIALLYLKHKVKFGNAVQPIC 159
++ Q + V ++ H Y NS E S DIAL++L + +QP+C
Sbjct: 221 --AVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN-SNDIALVHLSSPLPLTEYIQPVC 277
Query: 160 LPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRT 219
LP + + G +C +GWG + + VLQE +PI+ + CN N +
Sbjct: 278 LPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGN--QIKPK 335
Query: 220 MLCAGFPDWGMDACQGDSGGPLVCRRG---GGIWILAGITSWVAGCAGGSVPVRNNHVKA 276
M CAG+P+ G+DACQGDSGGP VC W L GI SW GCA P
Sbjct: 336 MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKP-------- 387
Query: 277 SLGIFSKVSELMDFITQNLFT 297
G+++KVS+ ++I Q + T
Sbjct: 388 --GVYTKVSDFREWIFQAIKT 406
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 172 bits (436), Expect = 2e-42
Identities = 96/242 (39%), Positives = 130/242 (53%), Gaps = 11/242 (4%)
Query: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLS-WTIIAGD 632
RI GG + WPWQV LR+ G + CGG++++ W+LTAAHC +N LS W + AG
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA 221
Query: 633 ----HDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHS 688
L+ + V + D N+ +DIAL+ LSSPL ++PVCLP +
Sbjct: 222 VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAA 281
Query: 689 AEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICA 748
+ L +IC VTGWG+ G A LQ+ +V ++ +VC + + I KM CA
Sbjct: 282 GQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADF--YGNQIKPKMFCA 339
Query: 749 GFAASGEKDFCQGDSGGPLVCR---HENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLD 805
G+ G D CQGDSGGP VC + L GIVSWG GC KPGV+ +V F +
Sbjct: 340 GYPEGG-IDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFRE 398
Query: 806 WI 807
WI
Sbjct: 399 WI 400
Score = 147 bits (370), Expect = 7e-35
Identities = 93/261 (35%), Positives = 133/261 (50%), Gaps = 25/261 (9%)
Query: 46 RISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSG 105
RI R++++ PWQVSL+ D H CGGSL+ D V+TAAHC + + L V +G
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN-RVLSRWRVFAG 220
Query: 106 EYSLFQKDKQEQNIPVSKIITHPEY------NSREYMSPDIALLYLKHKVKFGNAVQPIC 159
++ Q + V ++ H Y NS E S DIAL++L + +QP+C
Sbjct: 221 --AVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN-SNDIALVHLSSPLPLTEYIQPVC 277
Query: 160 LPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRT 219
LP + + G +C +GWG + + VLQE +PI+ + CN N +
Sbjct: 278 LPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGN--QIKPK 335
Query: 220 MLCAGFPDWGMDACQGDSGGPLVCRRG---GGIWILAGITSWVAGCAGGSVPVRNNHVKA 276
M CAG+P+ G+DACQGDSGGP VC W L GI SW GCA P
Sbjct: 336 MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKP-------- 387
Query: 277 SLGIFSKVSELMDFITQNLFT 297
G+++KVS+ ++I Q + T
Sbjct: 388 --GVYTKVSDFREWIFQAIKT 406
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 171 bits (433), Expect = 4e-42
Identities = 95/236 (40%), Positives = 138/236 (58%), Gaps = 12/236 (5%)
Query: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDH 633
R+ GGEEA WPWQV +++ + CGG+I++P W+LTAAHC + + +W + AG
Sbjct: 199 RVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSD 258
Query: 634 DRNLKESTEQVRRAKHIIVHEDFNTL-SYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPL 692
S + AK II+ +FN + D+DIAL++L PL ++ VRP+CLP E L
Sbjct: 259 KLG---SFPSLAVAKIIII--EFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEEL 313
Query: 693 FSSEICAVTGWGSISADGG-LASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFA 751
+ + GWG +GG ++ L Q V V++ C A+ G +TEKM+CAG
Sbjct: 314 TPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNAD--DAYQGEVTEKMMCAGIP 371
Query: 752 ASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWI 807
G D CQGDSGGPL+ +++ + + GIVSWG GC P PGV+ +V +L+WI
Sbjct: 372 EGG-VDTCQGDSGGPLM--YQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424
Score = 131 bits (329), Expect = 4e-30
Identities = 80/247 (32%), Positives = 125/247 (50%), Gaps = 22/247 (8%)
Query: 46 RISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSG 105
R+ ++V PWQVS++ D+ H CGGS++ V+TAAHC ++ + S
Sbjct: 199 RVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSD 258
Query: 106 EYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDD 165
+ F ++ V+KII E+N DIAL+ L+ + F V+PICLP D+
Sbjct: 259 KLGSF------PSLAVAKIII-IEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDE 311
Query: 166 KVEPGILCLSSGWGKISKT-SEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAG 224
++ P GWG + + S++L + + ++D CN + M+CAG
Sbjct: 312 ELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNA--DDAYQGEVTEKMMCAG 369
Query: 225 FPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKV 284
P+ G+D CQGDSGGPL+ + W + GI SW GC G S P G+++KV
Sbjct: 370 IPEGGVDTCQGDSGGPLMYQ--SDQWHVVGIVSWGYGCGGPSTP----------GVYTKV 417
Query: 285 SELMDFI 291
S +++I
Sbjct: 418 SAYLNWI 424
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 171 bits (433), Expect = 4e-42
Identities = 95/236 (40%), Positives = 138/236 (58%), Gaps = 12/236 (5%)
Query: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDH 633
R+ GGEEA WPWQV +++ + CGG+I++P W+LTAAHC + + +W + AG
Sbjct: 204 RVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSD 263
Query: 634 DRNLKESTEQVRRAKHIIVHEDFNTL-SYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPL 692
S + AK II+ +FN + D+DIAL++L PL ++ VRP+CLP E L
Sbjct: 264 KLG---SFPSLAVAKIIII--EFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEEL 318
Query: 693 FSSEICAVTGWGSISADGG-LASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFA 751
+ + GWG +GG ++ L Q V V++ C A+ G +TEKM+CAG
Sbjct: 319 TPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNAD--DAYQGEVTEKMMCAGIP 376
Query: 752 ASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDWI 807
G D CQGDSGGPL+ +++ + + GIVSWG GC P PGV+ +V +L+WI
Sbjct: 377 EGG-VDTCQGDSGGPLM--YQSDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429
Score = 131 bits (329), Expect = 4e-30
Identities = 80/247 (32%), Positives = 125/247 (50%), Gaps = 22/247 (8%)
Query: 46 RISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSG 105
R+ ++V PWQVS++ D+ H CGGS++ V+TAAHC ++ + S
Sbjct: 204 RVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSD 263
Query: 106 EYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDD 165
+ F ++ V+KII E+N DIAL+ L+ + F V+PICLP D+
Sbjct: 264 KLGSF------PSLAVAKIII-IEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDE 316
Query: 166 KVEPGILCLSSGWGKISKT-SEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAG 224
++ P GWG + + S++L + + ++D CN + M+CAG
Sbjct: 317 ELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNA--DDAYQGEVTEKMMCAG 374
Query: 225 FPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKV 284
P+ G+D CQGDSGGPL+ + W + GI SW GC G S P G+++KV
Sbjct: 375 IPEGGVDTCQGDSGGPLMYQ--SDQWHVVGIVSWGYGCGGPSTP----------GVYTKV 422
Query: 285 SELMDFI 291
S +++I
Sbjct: 423 SAYLNWI 429
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 171 bits (433), Expect = 4e-42
Identities = 99/247 (40%), Positives = 139/247 (56%), Gaps = 24/247 (9%)
Query: 575 IAGGEEACPHCWPWQVGLRFLGDYQ---CGGAIINPVWILTAAHCVQLKNNPLSWTIIAG 631
I GG+EA WPWQV LR Y CGG++I+P W+LTAAHCV L+ +
Sbjct: 31 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRV-- 88
Query: 632 DHDRNLKES----TEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPH 687
L+E +Q+ IIVH F T +DIAL++L P+ +S V V LP
Sbjct: 89 ----QLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVNVSSHVHTVTLPP 144
Query: 688 SAEPLFSSEICAVTGWGSISADGGLAS--RLQQIQVHVLEREVCEHTYY-SAHPGG---- 740
++E C VTGWG + D L L+Q++V ++E +C+ Y+ A+ G
Sbjct: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204
Query: 741 ITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARV 800
+ + M+CAG + +D CQGDSGGPLVC+ NG ++ G+VSWG GC QP +PG++ RV
Sbjct: 205 VRDDMLCAG---NTRRDSCQGDSGGPLVCK-VNGTWLQAGVVSWGEGCAQPNRPGIYTRV 260
Query: 801 MIFLDWI 807
+LDWI
Sbjct: 261 TYYLDWI 267
Score = 136 bits (343), Expect = 1e-31
Identities = 87/243 (35%), Positives = 132/243 (54%), Gaps = 28/243 (11%)
Query: 59 PWQVSLKSDEH---HFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQ 115
PWQVSL+ + HFCGGSLI V+TAAHC+ K L + V E L+ +D
Sbjct: 43 PWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGP-DVKDLAALRVQLREQHLYYQD-- 99
Query: 116 EQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLS 175
Q +PVS+II HP++ + + + DIALL L+ V + V + LP + + PG+ C
Sbjct: 100 -QLLPVSRIIVHPQFYTAQ-IGADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWV 157
Query: 176 SGWGKISKTSEYSN--VLQEMELPIMDDRACNT-----VLKSMNLPPLGRTMLCAGFPDW 228
+GWG + L+++++PIM++ C+ ++ + MLCAG +
Sbjct: 158 TGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAG--NT 215
Query: 229 GMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKASLGIFSKVSELM 288
D+CQGDSGGPLVC + G W+ AG+ SW GCA + P GI+++V+ +
Sbjct: 216 RRDSCQGDSGGPLVC-KVNGTWLQAGVVSWGEGCAQPNRP----------GIYTRVTYYL 264
Query: 289 DFI 291
D+I
Sbjct: 265 DWI 267
>gi|4503137 chymotrypsin-like [Homo sapiens]
Length = 264
Score = 169 bits (428), Expect = 1e-41
Identities = 98/254 (38%), Positives = 138/254 (54%), Gaps = 14/254 (5%)
Query: 561 CGIPPFSPQW-LSRRIAGGEEACPHCWPWQVGLR-FLGDYQCGGAIINPVWILTAAHCVQ 618
CGIP P S+RI GE A WPWQV L+ G + CGG++I+ W++TAAHC
Sbjct: 19 CGIPAIKPALSFSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVVTAAHC-- 76
Query: 619 LKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNS 678
+P ++ G++DR+ QV I H +N+ + ++D+ L++L+SP +Y +
Sbjct: 77 -NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLLKLASPAQYTT 135
Query: 679 VVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLA-SRLQQIQVHVLEREVCEHTYYSAH 737
+ PVCL S E L C TGWG +S G + + LQQ+ + ++ C + S+
Sbjct: 136 RISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCRQYWGSS- 194
Query: 738 PGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVF 797
IT+ MICAG A + CQGDSGGPLVC+ N +VL GIVSWG P V+
Sbjct: 195 ---ITDSMICAGGAGASS---CQGDSGGPLVCQKGN-TWVLIGIVSWGTKNCNVRAPAVY 247
Query: 798 ARVMIFLDWIQSKI 811
RV F WI I
Sbjct: 248 TRVSKFSTWINQVI 261
Score = 146 bits (368), Expect = 1e-34
Identities = 96/271 (35%), Positives = 144/271 (53%), Gaps = 32/271 (11%)
Query: 25 CGIRMVNMKSKEPAVGSRFFSRISSWRNSTVTGHPWQVSLK-SDEHHFCGGSLIQEDRVV 83
CGI + +PA+ F RI + N+ + PWQVSL+ S HFCGGSLI + VV
Sbjct: 19 CGIPAI-----KPALS--FSQRIVNGENAVLGSWPWQVSLQDSSGFHFCGGSLISQSWVV 71
Query: 84 TAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALL 143
TAAHC S V GEY + Q + VS+ ITHP +NS M+ D+ LL
Sbjct: 72 TAAHCNVSPGRH-----FVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTT-MNNDVTLL 125
Query: 144 YLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNV-LQEMELPIMDDR 202
L ++ + P+CL S++ + G+ C+++GWG++S + LQ++ LP++
Sbjct: 126 KLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVN 185
Query: 203 ACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGC 262
C S + +M+CAG G +CQGDSGGPLVC++ G W+L GI SW
Sbjct: 186 QCRQYWGS----SITDSMICAG--GAGASSCQGDSGGPLVCQK-GNTWVLIGIVSW---- 234
Query: 263 AGGSVPVRNNHVKASLGIFSKVSELMDFITQ 293
+N +V+A ++++VS+ +I Q
Sbjct: 235 -----GTKNCNVRAP-AVYTRVSKFSTWINQ 259
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 169 bits (427), Expect = 2e-41
Identities = 99/304 (32%), Positives = 152/304 (50%), Gaps = 23/304 (7%)
Query: 574 RIAGGEEACPHCWPWQVGLRFLGD-----YQCGGAIINPVWILTAAHCVQLKNNPLSWTI 628
RI GG+ A WPW V L+ + CGG+++N W+LTAAHC KNN W +
Sbjct: 42 RIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRL 101
Query: 629 IAGDHDRNLKESTE-----QVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPV 683
+ G + + Q R + II+HE +N+ + +DIAL++++ P+ + P
Sbjct: 102 VFGAKEITYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPG 161
Query: 684 CLPHSAEPL-FSSEICAVTGWGSISADGGLASR-LQQIQVHVLEREVCEHTYYSAHPGGI 741
CLPH L S+ C V GWG I S L + +V +++ ++C T + + G +
Sbjct: 162 CLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQW--YNGRV 219
Query: 742 TEKMICAGFAASGEKDFCQGDSGGPLVCRH-ENGPFVLYGIVSWGAGCVQPWKPGVFARV 800
+CAG+ G+ D CQGDSGGPL+C+ + +V+ GI SWG GC + +PG++
Sbjct: 220 QPTNVCAGYPV-GKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTAT 278
Query: 801 MIFLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSASWPGCCSEAELEKPRGFFPT 860
+L+WI SKI +N + ++ PPP + P P F P
Sbjct: 279 WPYLNWIASKIG-------SNALRMIQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPP 331
Query: 861 PRYL 864
PR L
Sbjct: 332 PRPL 335
Score = 110 bits (274), Expect = 1e-23
Identities = 77/224 (34%), Positives = 112/224 (50%), Gaps = 20/224 (8%)
Query: 59 PWQVSLK-----SDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKD 113
PW VSL+ S +H CGGSL+ V+TAAHC + + + + + G + +
Sbjct: 55 PWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCF--VGKNNVHDWRLVFGAKEITYGN 112
Query: 114 KQEQNIP-----VSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVE 168
+ P V KII H +YNS + DIAL+ + + G + P CLP +
Sbjct: 113 NKPVKAPLQERYVEKIIIHEKYNSATEGN-DIALVEITPPISCGRFIGPGCLPHFKAGLP 171
Query: 169 PGIL-CLSSGWGKIS-KTSEYSNVLQEMELPIMDDRACN-TVLKSMNLPPLGRTMLCAGF 225
G C +GWG I K S++L E + ++D CN T + + P T +CAG+
Sbjct: 172 RGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQP---TNVCAGY 228
Query: 226 PDWGMDACQGDSGGPLVCRRG-GGIWILAGITSWVAGCAGGSVP 268
P +D CQGDSGGPL+C+ +++ GITSW GCA P
Sbjct: 229 PVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRP 272
>gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
Length = 268
Score = 167 bits (422), Expect = 7e-41
Identities = 94/258 (36%), Positives = 145/258 (56%), Gaps = 15/258 (5%)
Query: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGD----YQCGGAIINPVWILTAAHC 616
CG+P F P LS R+ GGE+A PH WPWQ+ L++L + + CGG +I ++LTAAHC
Sbjct: 17 CGVPSFPPN-LSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHC 75
Query: 617 VQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHII-VHEDFNTLSYDSDIALIQLSSPLE 675
+ +N ++ + G ++ +++ + I VH+ +N L +DIALI+L+ +E
Sbjct: 76 I---SNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVE 132
Query: 676 YNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYS 735
+ ++ CLP L C VTGWG + +G +A +LQQ V++ C +
Sbjct: 133 LSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWW 192
Query: 736 AHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGA--GCVQPWK 793
+ + M+CAG G C GDSGGPL C+ ENG + ++GIVS+G+ GC K
Sbjct: 193 GF--RVKKTMVCAG--GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKK 248
Query: 794 PGVFARVMIFLDWIQSKI 811
P V+ RV ++DWI K+
Sbjct: 249 PVVYTRVSAYIDWINEKM 266
Score = 111 bits (278), Expect = 3e-24
Identities = 80/269 (29%), Positives = 131/269 (48%), Gaps = 32/269 (11%)
Query: 37 PAVGSRFFSRISSWRNSTVTGHPWQVSL---KSDE-HHFCGGSLIQEDRVVTAAHCLDSL 92
P+ +R+ ++ PWQ+SL K+D H CGG+LI + V+TAAHC+ +
Sbjct: 20 PSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNT 79
Query: 93 SEKQL----KNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHK 148
++ N+ V E SLF + V I H +N+ + DIAL+ L
Sbjct: 80 RTYRVAVGKNNLEVEDEEGSLF--------VGVDTIHVHKRWNAL-LLRNDIALIKLAEH 130
Query: 149 VKFGNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVL 208
V+ + +Q CLP+ D + C +GWG++ ++ LQ+ P++D C+ +
Sbjct: 131 VELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRI- 189
Query: 209 KSMNLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVA--GCAGGS 266
+ +TM+CAG D + AC GDSGGPL C+ G W + GI S+ + GC
Sbjct: 190 -DWWGFRVKKTMVCAG-GDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRK 247
Query: 267 VPVRNNHVKASLGIFSKVSELMDFITQNL 295
PV ++++VS +D+I + +
Sbjct: 248 KPV----------VYTRVSAYIDWINEKM 266
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 166 bits (421), Expect = 9e-41
Identities = 98/294 (33%), Positives = 145/294 (49%), Gaps = 24/294 (8%)
Query: 572 SRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNN---PLSWTI 628
S RI GG A P WPWQV L G + CGG++I P W+L+AAHC W++
Sbjct: 44 SARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSV 103
Query: 629 IAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHS 688
+ G H ++ R I+V +++ + +D+AL++L+SP V PVCLP +
Sbjct: 104 LLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCLPRA 163
Query: 689 AEPLFSSEICAVTGWGSISADGGLASR--LQQIQVHVLEREVCEHTYYSAHPGGITEK-- 744
+ C TGWG + L LQ++++ +L C+ Y P +T +
Sbjct: 164 SHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTLQIL 223
Query: 745 --MICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMI 802
M+CAG+ G +D CQGDSGGPLVC E G + GI S+G GC + +PGVF V
Sbjct: 224 PGMLCAGY-PEGRRDTCQGDSGGPLVC-EEGGRWFQAGITSFGFGCGRRNRPGVFTAVAT 281
Query: 803 FLDWIQSKI----NGPASLQTNNKCKTLKQQ---------LPPPTPSPDSASWP 843
+ WI+ ++ GPA K ++ Q+ LP +P +WP
Sbjct: 282 YEAWIREQVMGSEPGPAFPTQPQKTQSDPQEPREENCTIALPECGKAPRPGAWP 335
Score = 125 bits (315), Expect = 2e-28
Identities = 83/233 (35%), Positives = 114/233 (48%), Gaps = 13/233 (5%)
Query: 45 SRISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHC-LDSLSEKQLKNITVT 103
+RI N+ PWQVSL H CGGSLI V++AAHC + + + + +V
Sbjct: 45 ARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVL 104
Query: 104 SGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDS 163
G +S V+ I+ Y+ E + D+ALL L G AV P+CLP +
Sbjct: 105 LGVHSQDGPLDGAHTRAVAAIVVPANYSQVE-LGADLALLRLASPASLGPAVWPVCLPRA 163
Query: 164 DDKVEPGILCLSSGWGKISKTSEYSN--VLQEMELPIMDDRACNTVLKSMNLPPLGRT-- 219
+ G C ++GWG + + VLQE+EL ++ + C + P T
Sbjct: 164 SHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPG--PFNLTLQ 221
Query: 220 ----MLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVP 268
MLCAG+P+ D CQGDSGGPLVC GG W AGITS+ GC + P
Sbjct: 222 ILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGR-WFQAGITSFGFGCGRRNRP 273
Score = 82.4 bits (202), Expect = 2e-15
Identities = 64/223 (28%), Positives = 96/223 (43%), Gaps = 20/223 (8%)
Query: 578 GEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHD--R 635
G+ P WPW+ + G C GA+++ W+L A C +P S D D R
Sbjct: 326 GKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFL---DPNSSDSPPRDLDAWR 382
Query: 636 NLKESTEQVRRAKHIIVHEDFNTLSYD--SDIALIQLSSPLEYNSVVRPVCLPHSAEPLF 693
L S + R ++ HE+ S+D SD+AL+QL +P+ ++ RPVCLPH
Sbjct: 383 VLLPSRPRAERVARLVQHEN---ASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFL 439
Query: 694 SSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPG-----GITEKMICA 748
C + WG G + L + +L C H Y G +C
Sbjct: 440 PGSRCRLARWGRGEPALGPGALL---EAELLGGWWC-HCLYGRQGAAVPLPGDPPHALCP 495
Query: 749 GFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQP 791
+ E C DS L+C+ E G + L GI + +GC++P
Sbjct: 496 AYQEKEEVGSCWNDSRWSLLCQ-EEGTWFLAGIRDFPSGCLRP 537
Score = 70.9 bits (172), Expect = 7e-12
Identities = 54/202 (26%), Positives = 90/202 (44%), Gaps = 14/202 (6%)
Query: 586 WPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKESTEQVR 645
WPW + GD C G ++ P W+L A HCV L+ + I R S Q
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCV-LRPGSTTVPYIEVYLGRAGASSLPQGH 659
Query: 646 RAKHIIVHEDF-NTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPLFSSEICAVTGWG 704
+ +++ L +AL++LSS +E + P+CL + P +S C V GW
Sbjct: 660 QVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPGAS--CWVLGWK 717
Query: 705 SISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASGEKDFCQGDSG 764
+A+ V +L + +C+ Y P G +C + A G+++ C+ S
Sbjct: 718 EPQDRVPVAA-----AVSILTQRICDCLYQGILPPG----TLCVLY-AEGQENRCEMTSA 767
Query: 765 GPLVCRHENGPFVLYGIVSWGA 786
PL+C+ G ++L G+ G+
Sbjct: 768 PPLLCQMTEGSWILVGMAVQGS 789
Score = 58.2 bits (139), Expect = 4e-08
Identities = 52/209 (24%), Positives = 91/209 (43%), Gaps = 14/209 (6%)
Query: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
PW+ + C G+L+ E V+ A C + + + L + + E+
Sbjct: 335 PWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLLPSRPRAER- 393
Query: 119 IPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGW 178
V++++ H N+ + D+ALL L+ V A +P+CLP + PG C + W
Sbjct: 394 --VARLVQHE--NASWDNASDLALLQLRTPVNLSAASRPVCLPHPEHYFLPGSRCRLARW 449
Query: 179 GKISKTSEYSNVLQEMELPIMDDRACNTVL----KSMNLPPLGRTMLCAGFPD-WGMDAC 233
G+ + + L E EL + C+ + ++ LP LC + + + +C
Sbjct: 450 GR-GEPALGPGALLEAEL--LGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQEKEEVGSC 506
Query: 234 QGDSGGPLVCRRGGGIWILAGITSWVAGC 262
DS L+C+ G W LAGI + +GC
Sbjct: 507 WNDSRWSLLCQE-EGTWFLAGIRDFPSGC 534
Score = 57.4 bits (137), Expect = 8e-08
Identities = 49/197 (24%), Positives = 79/197 (40%), Gaps = 14/197 (7%)
Query: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
PW + C G L+ V+ A HC+ + I V G + Q
Sbjct: 602 PWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQ- 660
Query: 119 IPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILCLSSGW 178
VS+++ + P +ALL L +V+ + PICL + + PG C GW
Sbjct: 661 --VSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAG--IPPGASCWVLGW 716
Query: 179 GKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDACQGDSG 238
+ V + I+ R C+ + + + LPP LC + + + C+ S
Sbjct: 717 KE-----PQDRVPVAAAVSILTQRICDCLYQGI-LPP---GTLCVLYAEGQENRCEMTSA 767
Query: 239 GPLVCRRGGGIWILAGI 255
PL+C+ G WIL G+
Sbjct: 768 PPLLCQMTEGSWILVGM 784
>gi|15559207 elastase 2A preproprotein [Homo sapiens]
Length = 269
Score = 166 bits (419), Expect = 2e-40
Identities = 94/259 (36%), Positives = 147/259 (56%), Gaps = 17/259 (6%)
Query: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGD----YQCGGAIINPVWILTAAHC 616
CG P + P R+ GGEEA P+ WPWQV L++ + + CGG++I W+LTAAHC
Sbjct: 17 CGDPTYPPY--VTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHC 74
Query: 617 VQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNT--LSYDSDIALIQLSSPL 674
+ ++ ++ + G H+ + ES I+VH+D+N+ +S +DIAL++L++P+
Sbjct: 75 I---SSSRTYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPV 131
Query: 675 EYNSVVRPVCLPHSAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYY 734
++ CLP + L ++ C VTGWG + +G + LQQ ++ V++ C + +
Sbjct: 132 SLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAW 191
Query: 735 SAHPGGITEKMICAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGA--GCVQPW 792
+ MICAG G C GDSGGPL C+ +G + ++GIVS+G+ GC
Sbjct: 192 WG--SSVKTSMICAG--GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYH 247
Query: 793 KPGVFARVMIFLDWIQSKI 811
KP VF RV ++DWI S I
Sbjct: 248 KPSVFTRVSNYIDWINSVI 266
Score = 119 bits (298), Expect = 2e-26
Identities = 81/254 (31%), Positives = 128/254 (50%), Gaps = 21/254 (8%)
Query: 43 FFSRISSWRNSTVTGHPWQVSLKSDE----HHFCGGSLIQEDRVVTAAHCLDSLSEKQLK 98
+ +R+ + PWQVSL+ +H CGGSLI V+TAAHC+ S +
Sbjct: 25 YVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSS-----R 79
Query: 99 NITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSP-DIALLYLKHKVKFGNAVQP 157
V G ++L+ + + VSKI+ H ++NS + DIALL L + V + +Q
Sbjct: 80 TYRVGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQL 139
Query: 158 ICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLG 217
CLP + + C +GWG++ +VLQ+ L ++D C++ + +
Sbjct: 140 ACLPPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSS--SAWWGSSVK 197
Query: 218 RTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKAS 277
+M+CAG D + +C GDSGGPL C+ G W + GI S+ GS N + K S
Sbjct: 198 TSMICAG-GDGVISSCNGDSGGPLNCQASDGRWQVHGIVSF------GSRLGCNYYHKPS 250
Query: 278 LGIFSKVSELMDFI 291
+F++VS +D+I
Sbjct: 251 --VFTRVSNYIDWI 262
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,517,128
Number of Sequences: 37866
Number of extensions: 2237352
Number of successful extensions: 7333
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 214
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 5337
Number of HSP's gapped (non-prelim): 862
length of query: 1134
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1021
effective length of database: 13,968,660
effective search space: 14262001860
effective search space used: 14262001860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.