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Search of human proteins with 11068135
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
sapiens]
(423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo ... 875 0.0
gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo ... 287 1e-77
gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo ... 202 4e-52
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ... 190 2e-48
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo... 186 5e-47
gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo... 177 1e-44
gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo... 177 2e-44
gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo ... 142 7e-34
gi|212720861 tubulin tyrosine ligase-like family, member 11 a [H... 123 4e-28
gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo... 113 4e-25
gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo... 107 3e-23
gi|194239681 tubulin tyrosine ligase-like family, member 10 isof... 106 3e-23
gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Ho... 100 2e-21
gi|24308516 tubulin tyrosine ligase [Homo sapiens] 87 4e-17
gi|194239678 tubulin tyrosine ligase-like family, member 10 isof... 81 2e-15
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo... 63 6e-10
gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo... 49 9e-06
gi|163659918 sacsin [Homo sapiens] 30 5.4
gi|156071452 nardilysin isoform b [Homo sapiens] 30 5.4
gi|156071450 nardilysin isoform a [Homo sapiens] 30 5.4
gi|22749037 WD repeat domain 65 [Homo sapiens] 29 9.2
gi|38327558 guanylate binding protein 2, interferon-inducible [H... 29 9.2
>gi|11068135 tubulin tyrosine ligase-like family, member 1 [Homo
sapiens]
Length = 423
Score = 875 bits (2260), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ 60
MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ
Sbjct: 1 MAGKVKWVTDIEKSVLINNFEKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQ 60
Query: 61 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY 120
IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY
Sbjct: 61 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY 120
Query: 121 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI 180
NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI
Sbjct: 121 NLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI 180
Query: 181 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL 240
SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL
Sbjct: 181 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL 240
Query: 241 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM 300
TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM
Sbjct: 241 TNVAIQKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM 300
Query: 301 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE 360
NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE
Sbjct: 301 NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGE 360
Query: 361 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT 420
IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT
Sbjct: 361 IPDCKWNKSPPKEVLGNYEILYDEELAQGDGADRELRSRQGQSLGPRAGRSRDSGRAVLT 420
Query: 421 TWK 423
TWK
Sbjct: 421 TWK 423
>gi|56606131 tubulin tyrosine ligase-like family, member 9 [Homo
sapiens]
Length = 439
Score = 287 bits (734), Expect = 1e-77
Identities = 164/374 (43%), Positives = 215/374 (57%), Gaps = 44/374 (11%)
Query: 13 KSVLINNF-----EKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQI-VNHFP 66
K+ L+N + GWV+V + +W+FYW V +R F + D+ + ++HF
Sbjct: 47 KTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVSWLRENFD----HTYMDEHVRISHFR 102
Query: 67 NHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEE 126
NHYELTRK+ MVKN+KR+RK+LE+E L E K DF P T+ +P +Y+LFVEE
Sbjct: 103 NHYELTRKNYMVKNLKRFRKQLEREAGKL----EAAK---CDFFPKTFEMPCEYHLFVEE 155
Query: 127 FRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNK-EAYVISLYIN 185
FRK+P TWIMKP ++QGKGIFL +L I W +D+++S E YV YI
Sbjct: 156 FRKNPGITWIMKPVARSQGKGIFLFRRLKDIVDWRKDTRSSDDQKDDIPVENYVAQRYIE 215
Query: 186 NPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAI 245
NP LIGGRKFDLR+YVLV + C ++ S VHLTNVA+
Sbjct: 216 NPYLIGGRKFDLRVYVLVMSVFA-ECLLW----------------SGHRRQDVHLTNVAV 258
Query: 246 QKHGEDYNHIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKH 305
QK DY+ G KWT+ R YL S G E LF +I I V+SL++V V+ +DKH
Sbjct: 259 QKTSPDYHPKKGCKWTLQRFRQYLASKHGPEAVETLFRDIDNIFVKSLQSVQKVIISDKH 318
Query: 306 CFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIP--- 362
CFE YGYDI+ID LKPWL+EVNASPSLT+S+ D LK L+ DTL++ +
Sbjct: 319 CFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGRE 378
Query: 363 ------DCKWNKSP 370
D WN P
Sbjct: 379 KRVGGFDLMWNDGP 392
>gi|99028883 tubulin tyrosine ligase-like family, member 2 [Homo
sapiens]
Length = 592
Score = 202 bits (515), Expect = 4e-52
Identities = 128/364 (35%), Positives = 194/364 (53%), Gaps = 57/364 (15%)
Query: 11 IEKSVLINNFEKRGW----VQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFP 66
+ +SVL+ +RGW Q EDWN YW + + F + + Q +NH P
Sbjct: 98 VVQSVLL----ERGWNKFDKQEQNAEDWNLYWRT-----SSFRMTEHNSVKPWQQLNHHP 148
Query: 67 NHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEE 126
+LTRKD + K++K R+ G LY F+P+T+++P DY FV E
Sbjct: 149 GTTKLTRKDCLAKHLKHMRRMY-------------GTSLY-QFIPLTFVMPNDYTKFVAE 194
Query: 127 FRK------SPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVI 180
+ + + S WI KP ++G+GI + + D K F + Y++
Sbjct: 195 YFQERQMLGTKHSYWICKPAELSRGRGILIFS----------DFKDFIF-----DDMYIV 239
Query: 181 SLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHL 240
YI+NPLLIG K DLR+YV V+ ++PL Y+Y+ G RF T K+ S L N + HL
Sbjct: 240 QKYISNPLLIGRYKCDLRIYVCVTGFKPLTIYVYQEGLVRFATEKF--DLSNLQNNYAHL 297
Query: 241 TNVAIQKHGEDYNHI-----HGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKA 295
TN +I K G Y I HG KWT+S YL S ++ L+ +IH +++ ++ A
Sbjct: 298 TNSSINKSGASYEKIKEVIGHGCKWTLSRFFSYLRSWDVDDLL--LWKKIHRMVILTILA 355
Query: 296 VAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIA 355
+AP + +CFE +G+DI+IDD LKPWL+EVN SP+LT + D ++K L++D +++
Sbjct: 356 IAPSVPFAANCFELFGFDILIDDNLKPWLLEVNYSPALTLDCSTDVLVKRKLVHDIIDLI 415
Query: 356 VPNG 359
NG
Sbjct: 416 YLNG 419
>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
sapiens]
Length = 1281
Score = 190 bits (483), Expect = 2e-48
Identities = 113/314 (35%), Positives = 167/314 (53%), Gaps = 47/314 (14%)
Query: 56 LSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYM 115
LS+ Q VNHFP YELTRKD + KNI R + + +P T++
Sbjct: 113 LSEAQKVNHFPRSYELTRKDRLYKNIIRMQ--------------HTHGFKAFHILPQTFL 158
Query: 116 LPADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNK 175
LPA+Y F + K WI+KP ++G+G++LIN +QI S +
Sbjct: 159 LPAEYAEFCNSYSKD-RGPWIVKPVASSRGRGVYLINNPNQI---------------SLE 202
Query: 176 EAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDN 235
E ++S YINNPLLI KFD+RLYVLV++Y PL Y+Y+ G RF TV+Y + N
Sbjct: 203 ENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRN 262
Query: 236 MFVHLTNVAIQKHGEDYNHI-------HGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWI 288
F+HLTN ++ K DY +G KW++S + YL+ G++ T+ L + +
Sbjct: 263 QFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQ-EGRDTTA-LMAHVEDL 320
Query: 289 IVQSL--------KAVAPVMNNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTAND 340
I++++ A + + CFE YG+D++ID LKPWL+EVN SPSL D
Sbjct: 321 IIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLD 380
Query: 341 RILKYNLINDTLNI 354
+K ++I+D +
Sbjct: 381 LKIKASMISDMFTV 394
>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
1 [Homo sapiens]
Length = 891
Score = 186 bits (471), Expect = 5e-47
Identities = 114/346 (32%), Positives = 175/346 (50%), Gaps = 51/346 (14%)
Query: 21 EKRGWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKN 80
++ G+ + E++DW YW S+E + Q +NHFP E+ RKDL+ +N
Sbjct: 126 QQYGFREGGEDDDWTLYWTDYSV-----SLERVMEMKSYQKINHFPGMSEICRKDLLARN 180
Query: 81 IKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPC 140
+ R K K+ F P T+ LPAD+ R + T+I KP
Sbjct: 181 MSRMLKMFPKD---------------FRFFPRTWCLPADWGDLQTYSRSRKNKTYICKPD 225
Query: 141 GKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLY 200
QGKGIF+ + +IK E + LYI+ P +I G KFDLR+Y
Sbjct: 226 SGCQGKGIFITRTVKEIKPG---------------EDMICQLYISKPFIIDGFKFDLRIY 270
Query: 201 VLVSTYRPLRCYMYKLGFCRFCTVKYT-PSTSELDNMFVHLTNVAIQKHGEDYNHI--HG 257
VLV++ PLR ++Y G RF T Y+ P T LD++ +HLTN +I KH +++ G
Sbjct: 271 VLVTSCDPLRIFVYNEGLARFATTSYSRPCTDNLDDICMHLTNYSINKHSSNFSRDAHSG 330
Query: 258 GKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKH-----------C 306
K +S YLE +++ +I +I+++L + P++ ++ H C
Sbjct: 331 SKRKLSTFSAYLEDHSYN--VEQIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSAC 388
Query: 307 FECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTL 352
FE G+DI++D KLKPWL+EVN SPS ++ + D+ +K L+ DTL
Sbjct: 389 FEILGFDILLDHKLKPWLLEVNHSPSFSTDSRLDKEVKDGLLYDTL 434
>gi|217330594 tubulin tyrosine ligase-like family, member 4 [Homo
sapiens]
Length = 1199
Score = 177 bits (450), Expect = 1e-44
Identities = 111/350 (31%), Positives = 178/350 (50%), Gaps = 60/350 (17%)
Query: 31 NEDWNFYW---MSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKE 87
N+DW W M + R++ + Q +NHFP +++ RKD + +N+ R +
Sbjct: 634 NDDWLGCWGHHMKSPSFRSI---------REHQKLNHFPGSFQIGRKDRLWRNLSRMQSR 684
Query: 88 LEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKAQGKG 147
K+ F P +++LP D L + + S WI+KP A+G G
Sbjct: 685 FGKKE--------------FSFFPQSFILPQDAKLLRKAWESSSRQKWIVKPPASARGIG 730
Query: 148 IFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYR 207
I +I+K SQ+ K + ++ Y++ P LI G KFDLR+YV V++Y
Sbjct: 731 IQVIHKWSQLPK---------------RRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYD 775
Query: 208 PLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYN------HIHGGKWT 261
PLR Y++ G RF + KY+PS L N F+HLTN ++ K +Y G KW
Sbjct: 776 PLRIYLFSDGLVRFASCKYSPSMKSLGNKFMHLTNYSVNKKNAEYQANADEMACQGHKWA 835
Query: 262 VSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNN--------DKHCFECYGYD 313
+ L YL S +G + ++++I ++V+++ + P + + C E +G+D
Sbjct: 836 LKALWNYL-SQKGVN-SDAIWEKIKDVVVKTIISSEPYVTSLLKMYVRRPYSCHELFGFD 893
Query: 314 IIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIA---VPNGE 360
I++D+ LKPW++EVN SPSL SS+ D +K +I D LN+A +PN E
Sbjct: 894 IMLDENLKPWVLEVNISPSLHSSSPLDISIKGQMIRDLLNLAGFVLPNAE 943
>gi|75677580 tubulin tyrosine ligase-like family, member 13 [Homo
sapiens]
Length = 459
Score = 177 bits (449), Expect = 2e-44
Identities = 115/347 (33%), Positives = 174/347 (50%), Gaps = 53/347 (15%)
Query: 24 GWVQVTENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKR 83
G +V E+E+W YW S+E + Q +NHFP E+ RKDL+ +N+ R
Sbjct: 108 GLKEVGEDEEWTLYWTDCAV-----SLERVMDMKRFQKINHFPGMTEICRKDLLARNLNR 162
Query: 84 YRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLFVEEFRKSPSSTWIMKPCGKA 143
K E + P T+ LPADY F R+ + T+I KP
Sbjct: 163 MYKLYPSE---------------YNIFPRTWCLPADYGDFQSYGRQRKARTYICKPDSGC 207
Query: 144 QGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLV 203
QG+GIF+ +IK E + YI+ PLLI G KFD+R+YVL+
Sbjct: 208 QGRGIFITRNPREIKPG---------------EHMICQQYISKPLLIDGFKFDMRVYVLI 252
Query: 204 STYRPLRCYMYKLGFCRFCTVKYT-PSTSELDNMFVHLTNVAIQKHGEDY--NHIHGGKW 260
++ PLR + Y+ G RF T Y PS + LDN+ +HLTN AI KH E++ + G K
Sbjct: 253 TSCDPLRIFTYEEGLARFATTPYMEPSHNNLDNVCMHLTNYAINKHNENFVRDGAVGSKR 312
Query: 261 TVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDKH-------------CF 307
+S L ++L+ +L+ +I II++++ + V+ ++ CF
Sbjct: 313 KLSTLNIWLQEHSYNP--GELWGDIEDIIIKTIISAHSVLRHNYRTCFPQYLNGGTCACF 370
Query: 308 ECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNI 354
E G+DI++D KLKPWL+EVN SPS T+ + D+ +K L+ D + +
Sbjct: 371 EILGFDILLDHKLKPWLLEVNHSPSFTTDSCLDQEVKDALLCDAMTL 417
>gi|94536793 tubulin tyrosine ligase-like family, member 7 [Homo
sapiens]
Length = 887
Score = 142 bits (357), Expect = 7e-34
Identities = 99/347 (28%), Positives = 165/347 (47%), Gaps = 59/347 (17%)
Query: 30 ENEDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELE 89
E+E N W + S L + Q +NHFP E+ RKD + +N+ + K
Sbjct: 68 EDETSNLIWCDSAVQQEKIS-----ELQNYQRINHFPGMGEICRKDFLARNMTKMIKS-- 120
Query: 90 KEGSPLAEKDENGKYLYLDFVPVTYMLPADYNLF---VEEFRKS-PSSTWIMKPCGKAQG 145
+ L FVP T++ PA+Y F V+E +K T+I+KP A G
Sbjct: 121 -------------RPLDYTFVPRTWIFPAEYTQFQNYVKELKKKRKQKTFIVKPANGAMG 167
Query: 146 KGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLYVLVST 205
GI LI ++ +++ ++ YI P L+ G KFDLR+Y+LV++
Sbjct: 168 HGISLIRNGDKLP---------------SQDHLIVQEYIEKPFLMEGYKFDLRIYILVTS 212
Query: 206 YRPLRCYMYKLGFCRFCTVKY-TPSTSELDNMFVHLTNVAIQKHGE----DYNHIHGGKW 260
PL+ ++Y G R T KY P+ S L +++HLTN ++ KH E D G K
Sbjct: 213 CDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVNKHNEHFERDETENKGSKR 272
Query: 261 TVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSLKAVAPVM-------------NNDKHCF 307
++ +L++ + +K + +I ++V++L P + ++ CF
Sbjct: 273 SIKWFTEFLQA--NQHDVAKFWSDISELVVKTLIVAEPHVLHAYRMCRPGQPPGSESVCF 330
Query: 308 ECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNI 354
E G+DI++D KLKPWL+E+N +PS + D +K ++ + L +
Sbjct: 331 EVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKL 377
>gi|212720861 tubulin tyrosine ligase-like family, member 11 a [Homo
sapiens]
Length = 800
Score = 123 bits (308), Expect = 4e-28
Identities = 96/332 (28%), Positives = 155/332 (46%), Gaps = 63/332 (18%)
Query: 62 VNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYN 121
VN FP E+ RK + + ++ + +E +F P +++LP ++
Sbjct: 272 VNKFPGMTEMVRKITLSRAVRTMQNLFPEE---------------YNFYPRSWILPDEFQ 316
Query: 122 LFVEEFRK------SPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNK 175
LFV + + S T+I+KP G QG GI+LI S I+
Sbjct: 317 LFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIR----------LAGTLQS 366
Query: 176 EAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKY-TPSTSELD 234
V+ YI PLLI KFD+RLYVL+ + PL Y+ K G RFCT Y P+ L
Sbjct: 367 RPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLH 426
Query: 235 NMFVHLTNVAIQKHGEDYNHIH----GGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIV 290
+F+HLTN ++ H ++ H G K T S++ L S++G ++ K++ +I +++
Sbjct: 427 RIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRL-SSKGVDI-KKVWSDIISVVI 484
Query: 291 QSLKAVAPVM-----------NNDKHCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTAN 339
+++ A+ P + CF+ G+DI++ LKP L+EVNA+PS+ +
Sbjct: 485 KTVIALTPELKVFYQSDIPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIEHEH 544
Query: 340 --------------DRILKYNLINDTLNIAVP 357
D +K +I DTL + P
Sbjct: 545 ELSPGVFENVPSLVDEEVKVAVIRDTLRLMDP 576
>gi|109134340 tubulin tyrosine ligase-like family, member 3 [Homo
sapiens]
Length = 772
Score = 113 bits (282), Expect = 4e-25
Identities = 74/228 (32%), Positives = 115/228 (50%), Gaps = 14/228 (6%)
Query: 135 WIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRK 194
WI+KP K++G+GI ++ L ++ K + V + K +V+ YI PLLI G K
Sbjct: 280 WIVKPGAKSRGRGIMCMDHLEEMLKLVNGNPV---VMKDGK--WVVQKYIERPLLIFGTK 334
Query: 195 FDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNH 254
FDLR + LV+ + PL + Y+ + RF T + S LDN VHL N +IQKH E+ H
Sbjct: 335 FDLRQWFLVTDWNPLTVWFYRDSYIRFSTQPF--SLKNLDNS-VHLCNNSIQKHLENSCH 391
Query: 255 IH-----GGKWTVSNLRLYLESTRGKEVTSKLF-DEIHWIIVQSLKAVAPVMNNDKHCFE 308
H W+ + +L+ S + + ++ +L+ + K FE
Sbjct: 392 RHPLLPPDNMWSSQRFQAHLQEMGAPNAWSTIIVPGMKDAVIHALQTSQDTVQCRKASFE 451
Query: 309 CYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAV 356
YG D + + +PWLIE+NASP++ STA L + DTL + +
Sbjct: 452 LYGADFVFGEDFQPWLIEINASPTMAPSTAVTARLCAGVQADTLRVVI 499
>gi|122937293 tubulin tyrosine ligase-like family, member 8 [Homo
sapiens]
Length = 834
Score = 107 bits (266), Expect = 3e-23
Identities = 77/264 (29%), Positives = 132/264 (50%), Gaps = 31/264 (11%)
Query: 135 WIMKPCGKAQGKG----IFLINKLSQIKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLI 190
WI+KP K++G+G I ++++ +I + + +S+ NK +V+ YI PLLI
Sbjct: 331 WIIKPAAKSRGRGESPDIVCMDRVEEILELAAADHP---LSRDNK--WVVQKYIETPLLI 385
Query: 191 GGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKH-- 248
KFD+R + LV+ + PL + YK + RF T ++ S +LD+ +HL N A+QK+
Sbjct: 386 CDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRF--SLDKLDSA-IHLCNNAVQKYLK 442
Query: 249 ---GEDYNHIHGGKWTVSNLRLYLEST-RGKEVTSKLFDEIHWIIVQSLKAVAPVMNNDK 304
G WT + + YL+ RG S ++ + I ++K + K
Sbjct: 443 NDVGRSPLLPAHNMWTSTRFQEYLQRQGRGAVWGSVIYPSMKKAIAHAMKVAQDHVEPRK 502
Query: 305 HCFECYGYDIIIDDKLKPWLIEVNASPSLTSSTANDRILKYNLINDTLNIAVPNGEIPDC 364
+ FE YG D ++ +PWLIE+N+SP++ ST L + DT+ +AV C
Sbjct: 503 NSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVAVDR----SC 558
Query: 365 KWNKSPPKEVLGNYEILYDEELAQ 388
+GN+E+L+ + + +
Sbjct: 559 D---------IGNFELLWRQPVVE 573
>gi|194239681 tubulin tyrosine ligase-like family, member 10 isoform
1 [Homo sapiens]
Length = 673
Score = 106 bits (265), Expect = 3e-23
Identities = 98/391 (25%), Positives = 171/391 (43%), Gaps = 65/391 (16%)
Query: 14 SVLINNFEKRGWVQVTEN--EDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYEL 71
+++ + + +GW ++ ++ +D+ W V++ + S G +Q++ PN+ L
Sbjct: 168 TIISSYCKSKGWQRIHDSRRDDYTLKWCEVKSRDSYGSFREG-----EQLLYQLPNNKLL 222
Query: 72 TRKDLMVKNIKRYRKELEKEGS------PLAEKDENGKYL---------YL--------- 107
T K ++ ++ + + K EKD L YL
Sbjct: 223 TTKIGLLSTLRGRARAMSKASKVPGGVQARLEKDAAAPALEDLPWTSPGYLRPQRVLRME 282
Query: 108 DFVPVTYMLP------ADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWS 161
+F P TY L A + LF E + WI KP QGKGIFL+ ++ +
Sbjct: 283 EFFPETYRLDLKHEREAFFTLFDE------TQIWICKPTASNQGKGIFLLRNQEEVA--A 334
Query: 162 RDSKTSSFVSQS--------NKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYM 213
+KT S +A V+ YI NPLL+ GRKFD+R Y+L++ P +
Sbjct: 335 LQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIF- 393
Query: 214 YKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHI-HGGKWTVSNLRLYLEST 272
+ G+ R Y P +S+L HLTN +QK Y + W++ +L Y+ T
Sbjct: 394 FGHGYARLTLSLYDPHSSDLGG---HLTNQFMQKKSPLYMLLKEHTVWSMEHLNRYISDT 450
Query: 273 RGKE-------VTSKLFDEIHWIIVQSLKAVAPVMNNDKHCFECYGYDIIIDDKLKPWLI 325
K V + L + I+ A P ++ F+ G D +IDD K WL+
Sbjct: 451 FWKARGLAKDWVFTTLKKRMQQIMAHCFLAAKPKLDCKLGYFDLIGCDFLIDDNFKVWLL 510
Query: 326 EVNASPSLTSSTANDRILKYNLINDTLNIAV 356
E+N++P+L ++ + + ++ +TL++ +
Sbjct: 511 EMNSNPALHTNCEVLKEVIPGVVIETLDLVL 541
>gi|89363028 tubulin tyrosine ligase-like family, member 11 b [Homo
sapiens]
Length = 538
Score = 100 bits (249), Expect = 2e-21
Identities = 74/248 (29%), Positives = 121/248 (48%), Gaps = 38/248 (15%)
Query: 62 VNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADYN 121
VN FP E+ RK + + ++ + +E +F P +++LP ++
Sbjct: 272 VNKFPGMTEMVRKITLSRAVRTMQNLFPEE---------------YNFYPRSWILPDEFQ 316
Query: 122 LFVEEFRK------SPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNK 175
LFV + + S T+I+KP G QG GI+LI S I+
Sbjct: 317 LFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKDPSDIR----------LAGTLQS 366
Query: 176 EAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKY-TPSTSELD 234
V+ YI PLLI KFD+RLYVL+ + PL Y+ K G RFCT Y P+ L
Sbjct: 367 RPAVVQEYICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLH 426
Query: 235 NMFVHLTNVAIQKHGEDYNHIH----GGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIV 290
+F+HLTN ++ H ++ H G K T S++ L S++G ++ K++ +I +++
Sbjct: 427 RIFMHLTNYSLNIHSGNFIHSDSASTGSKRTFSSILCRL-SSKGVDI-KKVWSDIISVVI 484
Query: 291 QSLKAVAP 298
+++ A+ P
Sbjct: 485 KTVIALTP 492
>gi|24308516 tubulin tyrosine ligase [Homo sapiens]
Length = 377
Score = 86.7 bits (213), Expect = 4e-17
Identities = 67/223 (30%), Positives = 108/223 (48%), Gaps = 26/223 (11%)
Query: 118 ADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKEA 177
A YN E+ + WI K A+G+GI + ++ S++ F+ +
Sbjct: 133 ASYNRKKED---GEGNVWIAKSSAGAKGEGILISSEASELL---------DFIDNQG-QV 179
Query: 178 YVISLYINNPLLI--GGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTSELDN 235
+VI Y+ +PLL+ G RKFD+R +VLV Y+Y+ G R + Y +
Sbjct: 180 HVIQKYLEHPLLLEPGHRKFDIRSWVLVD--HQYNIYLYREGVLRTASEPY--HVDNFQD 235
Query: 236 MFVHLTNVAIQK-HGEDYN-HIHGGKWTVSNLRLYLESTRGKEVTSKLFDEIHWIIVQSL 293
HLTN IQK + ++Y + G + YL S + S + +I II L
Sbjct: 236 KTCHLTNHCIQKEYSKNYGKYEEGNEMFFKEFNQYLTSALNITLESSILLQIKHIIRNCL 295
Query: 294 KAVAPVMNNDKHC----FECYGYDIIIDDKLKPWLIEVNASPS 332
+V P ++ KH F+ +G+D ++D++LK WLIEVN +P+
Sbjct: 296 LSVEPAIST-KHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPA 337
>gi|194239678 tubulin tyrosine ligase-like family, member 10 isoform
2 [Homo sapiens]
Length = 404
Score = 81.3 bits (199), Expect = 2e-15
Identities = 77/300 (25%), Positives = 128/300 (42%), Gaps = 58/300 (19%)
Query: 14 SVLINNFEKRGWVQVTEN--EDWNFYWMSVQTIRNVFSVEAGYRLSDDQIVNHFPNHYEL 71
+++ + + +GW ++ ++ +D+ W V++ + S G +Q++ PN+ L
Sbjct: 95 TIISSYCKSKGWQRIHDSRRDDYTLKWCEVKSRDSYGSFREG-----EQLLYQLPNNKLL 149
Query: 72 TRKDLMVKNIKRYRKELEKEGS------PLAEKDENGKYL---------YL--------- 107
T K ++ ++ + + K EKD L YL
Sbjct: 150 TTKIGLLSTLRGRARAMSKASKVPGGVQARLEKDAAAPALEDLPWTSPGYLRPQRVLRME 209
Query: 108 DFVPVTYMLP------ADYNLFVEEFRKSPSSTWIMKPCGKAQGKGIFLINKLSQIKKWS 161
+F P TY L A + LF E + WI KP QGKGIFL+ ++ +
Sbjct: 210 EFFPETYRLDLKHEREAFFTLFDE------TQIWICKPTASNQGKGIFLLRNQEEVA--A 261
Query: 162 RDSKTSSFVSQS--------NKEAYVISLYINNPLLIGGRKFDLRLYVLVSTYRPLRCYM 213
+KT S +A V+ YI NPLL+ GRKFD+R Y+L++ P +
Sbjct: 262 LQAKTRSMEDDPIHHKTPFRGPQARVVQRYIQNPLLVDGRKFDVRSYLLIACTTPYMIF- 320
Query: 214 YKLGFCRFCTVKYTPSTSELDNMFVHLTNVAIQKHGEDYNHI-HGGKWTVSNLRLYLEST 272
+ G+ R Y P +S+L HLTN +QK Y + W++ +L Y+ T
Sbjct: 321 FGHGYARLTLSLYDPHSSDLGG---HLTNQFMQKKSPLYMLLKEHTVWSMEHLNRYISDT 377
>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
2 [Homo sapiens]
Length = 584
Score = 62.8 bits (151), Expect = 6e-10
Identities = 30/84 (35%), Positives = 53/84 (63%), Gaps = 11/84 (13%)
Query: 280 KLFDEIHWIIVQSLKAVAPVMNNDKH-----------CFECYGYDIIIDDKLKPWLIEVN 328
+++ +I +I+++L + P++ ++ H CFE G+DI++D KLKPWL+EVN
Sbjct: 44 QIWRDIEDVIIKTLISAHPIIRHNYHTCFPNHTLNSACFEILGFDILLDHKLKPWLLEVN 103
Query: 329 ASPSLTSSTANDRILKYNLINDTL 352
SPS ++ + D+ +K L+ DTL
Sbjct: 104 HSPSFSTDSRLDKEVKDGLLYDTL 127
>gi|11056036 tubulin tyrosine ligase-like family, member 12 [Homo
sapiens]
Length = 644
Score = 48.9 bits (115), Expect = 9e-06
Identities = 48/190 (25%), Positives = 78/190 (41%), Gaps = 40/190 (21%)
Query: 61 IVNHFPNHYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLYLDFVPVTYMLPADY 120
++N FP LT KD + +R EG P ++P T+ L +
Sbjct: 355 LLNQFPCENLLTVKDCLASIARRAGGP---EGPP--------------WLPRTFNLRTEL 397
Query: 121 NLFVEEFRK----SPSSTWIMKPCGKAQGKGIFLINKLSQIKKWSRDSKTSSFVSQSNKE 176
FV F++ + WI KP A+ + L I +
Sbjct: 398 PQFVSYFQQRERWGEDNHWICKPWNLARSLDTHVTKSLHSI------------IRHREST 445
Query: 177 AYVISLYINNPLL-----IGGRKFDLRLYVLVSTYRPLRCYMYKLGFCRFCTVKYTPSTS 231
V+S YI +P+L +G KFD+R VL+ + RPLR ++Y + + RF + + +
Sbjct: 446 PKVVSKYIESPVLFLREDVGKVKFDIRYIVLLRSVRPLRLFVYDVFWLRFSNRAF--ALN 503
Query: 232 ELDNMFVHLT 241
+LD+ H T
Sbjct: 504 DLDDYEKHFT 513
>gi|163659918 sacsin [Homo sapiens]
Length = 4579
Score = 29.6 bits (65), Expect = 5.4
Identities = 24/85 (28%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 62 VNHFPN-HYELTRKDLMVKNIKRYRKELEKEGSPLAEKDENGKYLY---LDF-VPVTYML 116
+ H N Y +T + + +N+ R + L + G L + LY +D +PV+Y+
Sbjct: 3035 LQHLKNADYNITTRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLIDADIPVSYVT 3094
Query: 117 PADYNLFVEEFRKSPSSTWIMK-PC 140
PAD F+ F ++ I K PC
Sbjct: 3095 PADIRSFLMTFSSPDTNCHIGKLPC 3119
>gi|156071452 nardilysin isoform b [Homo sapiens]
Length = 1151
Score = 29.6 bits (65), Expect = 5.4
Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 38 WMSVQTIRNVFS-----VEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEG 92
W V T + +F +EA S +VN F H K L V + + ELE++G
Sbjct: 1040 WNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYELEEDG 1099
Query: 93 SPLAEKDENG-KYLYLDFVPVTYML 116
+P +E + + + L ++P + +L
Sbjct: 1100 TPSSEDSNSSCEVMQLTYLPTSPLL 1124
>gi|156071450 nardilysin isoform a [Homo sapiens]
Length = 1219
Score = 29.6 bits (65), Expect = 5.4
Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 6/85 (7%)
Query: 38 WMSVQTIRNVFS-----VEAGYRLSDDQIVNHFPNHYELTRKDLMVKNIKRYRKELEKEG 92
W V T + +F +EA S +VN F H K L V + + ELE++G
Sbjct: 1108 WNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYELEEDG 1167
Query: 93 SPLAEKDENG-KYLYLDFVPVTYML 116
+P +E + + + L ++P + +L
Sbjct: 1168 TPSSEDSNSSCEVMQLTYLPTSPLL 1192
>gi|22749037 WD repeat domain 65 [Homo sapiens]
Length = 698
Score = 28.9 bits (63), Expect = 9.2
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 157 IKKWSRDSKTSSFVSQSNKEAYVISLYINNPLLIGGRKFDLRLY-VLVSTYRPLRCYMYK 215
I+ W+ ++ T + +EAY ISL+ + ++ G LRL +L+ R + Y +
Sbjct: 413 IRLWNYETNTLELFKEYQEEAYSISLHPSGHFIVVGFADKLRLMNLLIDDIRSFKEYSVR 472
Query: 216 -LGFCRF 221
G C F
Sbjct: 473 GCGECSF 479
>gi|38327558 guanylate binding protein 2, interferon-inducible [Homo
sapiens]
Length = 591
Score = 28.9 bits (63), Expect = 9.2
Identities = 15/58 (25%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 45 RNVFSVEAGYRLSDDQIVNHFPNHYELTRKDLMVKNI-KRYRKELEKEGSPLAEKDEN 101
+ FS GYRL ++ +Y++ RK + K + K+Y + E L + D++
Sbjct: 422 QGTFSKPGGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQS 479
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,343,848
Number of Sequences: 37866
Number of extensions: 730559
Number of successful extensions: 1708
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1639
Number of HSP's gapped (non-prelim): 24
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.