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Search of human proteins with 167466272
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167466272 cytoskeleton associated protein 2-like [Homo
sapiens]
(745 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens] 1474 0.0
gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo s... 148 2e-35
gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo s... 148 2e-35
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 44 5e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 43 0.001
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 42 0.002
gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens] 42 0.003
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 42 0.003
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 40 0.010
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 40 0.010
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 40 0.010
gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens] 38 0.030
gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens] 38 0.030
gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens] 38 0.030
gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens] 38 0.030
gi|33457320 UBX domain containing 4 [Homo sapiens] 38 0.030
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 37 0.051
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 37 0.051
gi|4557719 DNA ligase I [Homo sapiens] 37 0.067
gi|56788356 tuftelin interacting protein 11 [Homo sapiens] 37 0.067
gi|8393259 tuftelin interacting protein 11 [Homo sapiens] 37 0.067
gi|23503243 Ras association (RalGDS/AF-6) domain family (N-termi... 37 0.067
gi|32528306 replication factor C large subunit [Homo sapiens] 37 0.087
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 36 0.11
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 36 0.11
gi|94536834 PAP associated domain containing 5 isoform a [Homo s... 36 0.11
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens] 35 0.19
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 35 0.19
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 35 0.19
gi|115527120 nebulin [Homo sapiens] 35 0.19
>gi|167466272 cytoskeleton associated protein 2-like [Homo sapiens]
Length = 745
Score = 1474 bits (3817), Expect = 0.0
Identities = 745/745 (100%), Positives = 745/745 (100%)
Query: 1 MVGPGPTAAAAVEERQRKLQEYLAAKGKLKSQNTKPYLKSKNNCQNQPPSKSTIRPKNDV 60
MVGPGPTAAAAVEERQRKLQEYLAAKGKLKSQNTKPYLKSKNNCQNQPPSKSTIRPKNDV
Sbjct: 1 MVGPGPTAAAAVEERQRKLQEYLAAKGKLKSQNTKPYLKSKNNCQNQPPSKSTIRPKNDV 60
Query: 61 TNHVVLPVKPKRSISIKLQPRPPNTAGSQKPKLEPPKLLGKRLTSECVSSNPYSKPSSKS 120
TNHVVLPVKPKRSISIKLQPRPPNTAGSQKPKLEPPKLLGKRLTSECVSSNPYSKPSSKS
Sbjct: 61 TNHVVLPVKPKRSISIKLQPRPPNTAGSQKPKLEPPKLLGKRLTSECVSSNPYSKPSSKS 120
Query: 121 FQQCEAGSSTTGELSRKPVGSLNIEQLKTTKQQLTDQGNGKCIDFMNNIHVENESLDNFL 180
FQQCEAGSSTTGELSRKPVGSLNIEQLKTTKQQLTDQGNGKCIDFMNNIHVENESLDNFL
Sbjct: 121 FQQCEAGSSTTGELSRKPVGSLNIEQLKTTKQQLTDQGNGKCIDFMNNIHVENESLDNFL 180
Query: 181 KETNKENLLDILTEPERKPDPKLYTRSKPKTDSYNQTKNSLVPKQALGKSSVNSAVLKDR 240
KETNKENLLDILTEPERKPDPKLYTRSKPKTDSYNQTKNSLVPKQALGKSSVNSAVLKDR
Sbjct: 181 KETNKENLLDILTEPERKPDPKLYTRSKPKTDSYNQTKNSLVPKQALGKSSVNSAVLKDR 240
Query: 241 VNKQFVGETQSRTFPVKSQQLSRGADLARPGVKPSRTVPSHFIRTLSKVQSSKKPVVKNI 300
VNKQFVGETQSRTFPVKSQQLSRGADLARPGVKPSRTVPSHFIRTLSKVQSSKKPVVKNI
Sbjct: 241 VNKQFVGETQSRTFPVKSQQLSRGADLARPGVKPSRTVPSHFIRTLSKVQSSKKPVVKNI 300
Query: 301 KDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQV 360
KDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQV
Sbjct: 301 KDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQV 360
Query: 361 CIPQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDS 420
CIPQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDS
Sbjct: 361 CIPQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDS 420
Query: 421 KLKKAVPQNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQLEEWQKSKGKTYK 480
KLKKAVPQNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQLEEWQKSKGKTYK
Sbjct: 421 KLKKAVPQNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQLEEWQKSKGKTYK 480
Query: 481 RPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLELSSKINNTLTECLNLIEGGVPSNE 540
RPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLELSSKINNTLTECLNLIEGGVPSNE
Sbjct: 481 RPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLELSSKINNTLTECLNLIEGGVPSNE 540
Query: 541 ILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIGLYEEAIKNGATPIQELRKVVLNILQ 600
ILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIGLYEEAIKNGATPIQELRKVVLNILQ
Sbjct: 541 ILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIGLYEEAIKNGATPIQELRKVVLNILQ 600
Query: 601 DSNRTTEGITSDSLVAETSITSVEELAKKMESVKSCLSPKEREQVTATPRIAKAEQHNYP 660
DSNRTTEGITSDSLVAETSITSVEELAKKMESVKSCLSPKEREQVTATPRIAKAEQHNYP
Sbjct: 601 DSNRTTEGITSDSLVAETSITSVEELAKKMESVKSCLSPKEREQVTATPRIAKAEQHNYP 660
Query: 661 GIKLQIGPIPRINGMPEVQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVVASLDELLEV 720
GIKLQIGPIPRINGMPEVQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVVASLDELLEV
Sbjct: 661 GIKLQIGPIPRINGMPEVQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVVASLDELLEV 720
Query: 721 EETKCFIFRRNEALPVTLGFQTPES 745
EETKCFIFRRNEALPVTLGFQTPES
Sbjct: 721 EETKCFIFRRNEALPVTLGFQTPES 745
>gi|148664201 cytoskeleton associated protein 2 isoform 2 [Homo
sapiens]
Length = 683
Score = 148 bits (373), Expect = 2e-35
Identities = 130/504 (25%), Positives = 226/504 (44%), Gaps = 72/504 (14%)
Query: 287 SKVQSSKKPV-VKNIKDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPS------- 338
SK+ S +KP+ VK+ + P TK + + VK + +
Sbjct: 186 SKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVST 245
Query: 339 ------LLQGEYNNRHPNIKQDQKSSQVCIPQTSCVLQKSKAISQRPNLTVGRFNSAIPS 392
L++ + H N + K I +TS + K ++ L + +A+ S
Sbjct: 246 TSQNTQLVRPPIRSHHSNTRDTVKQG---ISRTSANVTIRKGPHEKELL---QSKTALSS 299
Query: 393 TPSIRPNGTSGNKHNNNGFQQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTN 452
+ G NK + + + L + + K+ P Q T +
Sbjct: 300 VKTSSSQGIIRNKTLSRSIASEVIARPASLSN----DKLMEKSEPVDQRRHTAGKAIVDS 355
Query: 453 PNIKKKATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNI---SFWKSIEKEEE 509
+ + K T+E+R+ +L EW+ KG+ KRPP + T+ + + SFW ++ +E+E
Sbjct: 356 RSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDE 415
Query: 510 EKKAQLELSSKINNTLTECLNLIEGGVPSNEIL----NILSSIPEAEKFAKFWICKAKLL 565
++ + K+NNT +ECLNLI G P +IL +++ +IP+A+K K+WIC A +
Sbjct: 416 QRL----FTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIE 471
Query: 566 ASKGTFD-VIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGI--------TSDSLVA 616
+ +I +YE+AI GA PI+E+R +++IL ++ + S V
Sbjct: 472 PITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVK 531
Query: 617 ETSI--TSVEELAKKMES---------VKSCLSPKEREQVTATP----RIAKAEQHNYPG 661
E SI T V+ +K+E + C KE++ T P + E
Sbjct: 532 EVSIEDTGVDVDPEKLEMESKLHRNLLFQDC--EKEQDNKTKDPTHDVKTPNTETRTSCL 589
Query: 662 IKLQIGPIPRINGMPE----------VQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVV 711
IK + P + + + +++KF+TPVRRS R++ S+ P+ML++H V
Sbjct: 590 IKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCV 649
Query: 712 ASLDELLEV-EETKCFIFRRNEAL 734
+SL++L E+ ET F+ R N AL
Sbjct: 650 SSLEQLTELGRETDAFVCRPNAAL 673
>gi|148664244 cytoskeleton associated protein 2 isoform 1 [Homo
sapiens]
Length = 682
Score = 148 bits (373), Expect = 2e-35
Identities = 130/504 (25%), Positives = 226/504 (44%), Gaps = 72/504 (14%)
Query: 287 SKVQSSKKPV-VKNIKDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPS------- 338
SK+ S +KP+ VK+ + P TK + + VK + +
Sbjct: 185 SKINSFRKPLQVKDESSAATKKLSATIPKATKPQPVNTSSVTVKSNRSSNMTATTKFVST 244
Query: 339 ------LLQGEYNNRHPNIKQDQKSSQVCIPQTSCVLQKSKAISQRPNLTVGRFNSAIPS 392
L++ + H N + K I +TS + K ++ L + +A+ S
Sbjct: 245 TSQNTQLVRPPIRSHHSNTRDTVKQG---ISRTSANVTIRKGPHEKELL---QSKTALSS 298
Query: 393 TPSIRPNGTSGNKHNNNGFQQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTN 452
+ G NK + + + L + + K+ P Q T +
Sbjct: 299 VKTSSSQGIIRNKTLSRSIASEVIARPASLSN----DKLMEKSEPVDQRRHTAGKAIVDS 354
Query: 453 PNIKKKATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNI---SFWKSIEKEEE 509
+ + K T+E+R+ +L EW+ KG+ KRPP + T+ + + SFW ++ +E+E
Sbjct: 355 RSAQPKETSEERKARLSEWKAGKGRVLKRPPNSVVTQHEPAGQNEKPVGSFWTTMAEEDE 414
Query: 510 EKKAQLELSSKINNTLTECLNLIEGGVPSNEIL----NILSSIPEAEKFAKFWICKAKLL 565
++ + K+NNT +ECLNLI G P +IL +++ +IP+A+K K+WIC A +
Sbjct: 415 QRL----FTEKVNNTFSECLNLINEGCPKEDILVTLNDLIKNIPDAKKLVKYWICLALIE 470
Query: 566 ASKGTFD-VIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGI--------TSDSLVA 616
+ +I +YE+AI GA PI+E+R +++IL ++ + S V
Sbjct: 471 PITSPIENIIAIYEKAILAGAQPIEEMRHTIVDILTMKSQEKANLGENMEKSCASKEEVK 530
Query: 617 ETSI--TSVEELAKKMES---------VKSCLSPKEREQVTATP----RIAKAEQHNYPG 661
E SI T V+ +K+E + C KE++ T P + E
Sbjct: 531 EVSIEDTGVDVDPEKLEMESKLHRNLLFQDC--EKEQDNKTKDPTHDVKTPNTETRTSCL 588
Query: 662 IKLQIGPIPRINGMPE----------VQDMKFITPVRRSSRIERAVSRYPEMLQEHDLVV 711
IK + P + + + +++KF+TPVRRS R++ S+ P+ML++H V
Sbjct: 589 IKYNVSTTPYLQSVKKKVQFDGTNSAFKELKFLTPVRRSRRLQEKTSKLPDMLKDHYPCV 648
Query: 712 ASLDELLEV-EETKCFIFRRNEAL 734
+SL++L E+ ET F+ R N AL
Sbjct: 649 SSLEQLTELGRETDAFVCRPNAAL 672
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 43.9 bits (102), Expect = 5e-04
Identities = 53/205 (25%), Positives = 94/205 (45%), Gaps = 22/205 (10%)
Query: 458 KATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLEL 517
K AEDR KQLEE +K K + E + +V++E++ + + EE KA+ ++
Sbjct: 29 KKAAEDRSKQLEEDIAAKEKLLRVSEDE---RDRVLEELHKAEDSLLAAEEAAAKAEADV 85
Query: 518 SSKINNTLTECLNLIEGGV--PSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIG 575
+S L + L+E + + L + EAEK A K++ S+ D
Sbjct: 86 AS-----LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKD--- 137
Query: 576 LYEEAIKNGATPIQELR-KVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKMESVK 634
EE ++ IQE++ K +I +D++R E + ++ E+ + EE A+ E K
Sbjct: 138 --EEKME-----IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEG-K 189
Query: 635 SCLSPKEREQVTATPRIAKAEQHNY 659
+E + VT + +A+ Y
Sbjct: 190 CAELEEELKTVTNNLKSLEAQAEKY 214
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 43.1 bits (100), Expect = 0.001
Identities = 102/519 (19%), Positives = 180/519 (34%), Gaps = 88/519 (16%)
Query: 13 EERQRKLQEYLAAKGKLKSQNTKPYLKSKNNCQNQPPSKSTIRPKNDVTNHVVLPVKPKR 72
EE Q+K K + K+ P K+K++ + S PKN KPK
Sbjct: 138 EEDQKKQPVQKGVKPQAKAAKAPPK-KAKSSDSDSDSSSEDEPPKNQ---------KPKI 187
Query: 73 S-ISIKLQPRPPNTAGSQKPKLEPPKLLGKRLTSECVSSNPYSKPSSKSFQQCEAGSSTT 131
+ +++K Q + P KP PK+ + S SS+ S SS ++ +A ++
Sbjct: 188 TPVTVKAQTKAP-----PKPARAAPKIANGKAASSSSSSS--SSSSSDDSEEEKAAATPK 240
Query: 132 GELSRKPVGSLNIEQLKTTKQQLTDQGNGKCIDFMNNIHVENESLDNFLKETNKENLLDI 191
+ +K V + + TT + K ++ E+
Sbjct: 241 KTVPKKQVVAKAPVKAATTPTR---------------------------KSSSSEDSSSD 273
Query: 192 LTEPERKPDPKLYTRSKPKTDSYNQTKNSLVPKQALGKSSVNSAVLKDRVNKQFVGETQS 251
E ++KP ++KP S ++ PK++LG AV K +
Sbjct: 274 EEEEQKKP-----MKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQ----------- 317
Query: 252 RTFPVKSQQLSRGADLARPGVKPSRTVPSHFIRTLSKVQSSKKPVVKNIKDIKVNRSQYE 311
PV+S + S +D + + + P+ + +SK ++K P K + + S +
Sbjct: 318 ---PVESSEDS--SDESDSSSEEEKKPPTKAV--VSKA-TTKPPPAKKAAESSSDSSDSD 369
Query: 312 RPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQVCIPQTSCVLQK 371
+ + S P + KP + P +K Q + +K
Sbjct: 370 SSEDDEAPSKPAGTTKNSSNKPAV---------TTKSPAVKPAAAPKQPVGGGQKLLTRK 420
Query: 372 SKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQ----QKAQTLDSKLKKAVP 427
+ + S + + +P T+ + Q + + DS +
Sbjct: 421 ADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEE 480
Query: 428 QNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQL------EEWQKSKGKTYKR 481
+ +K+A K + + P KK AE EE +K KGK R
Sbjct: 481 EEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPR 540
Query: 482 PPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLELSSK 520
P + N K+ E+EEEEKK + SK
Sbjct: 541 PQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSK 579
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 42.0 bits (97), Expect = 0.002
Identities = 51/202 (25%), Positives = 89/202 (44%), Gaps = 21/202 (10%)
Query: 458 KATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLEL 517
K AEDR KQLEE Q++ K K E++ + +KE EK E+ +K +
Sbjct: 29 KKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQ-------EKLEQAEKKATDA 81
Query: 518 SSKINNTLTECLNLIEGGV--PSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIG 575
+ + +L + L+E + + L + EAEK A K++ ++ D
Sbjct: 82 EADV-ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKD--- 137
Query: 576 LYEEAIKNGATPIQELR-KVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKMESVK 634
EE ++ +QE++ K +I +DS+R E + ++ E + EE A+ ES
Sbjct: 138 --EEKME-----LQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRA 190
Query: 635 SCLSPKEREQVTATPRIAKAEQ 656
L + R A + +E+
Sbjct: 191 RQLEEELRTMDQALKSLMASEE 212
>gi|63252906 tropomyosin 1 alpha chain isoform 7 [Homo sapiens]
Length = 284
Score = 41.6 bits (96), Expect = 0.003
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 21/177 (11%)
Query: 458 KATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLEL 517
K AEDR KQLEE +K K + E + +V++E++ + + EE KA+ ++
Sbjct: 29 KKAAEDRSKQLEEDIAAKEKLLRVSEDE---RDRVLEELHKAEDSLLAAEEAAAKAEADV 85
Query: 518 SSKINNTLTECLNLIEGGV--PSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIG 575
+S L + L+E + + L + EAEK A K++ S+ D
Sbjct: 86 AS-----LNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKD--- 137
Query: 576 LYEEAIKNGATPIQELR-KVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKME 631
EE ++ IQE++ K +I +D++R E + ++ E+ + EE A+ E
Sbjct: 138 --EEKME-----IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSE 187
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 41.6 bits (96), Expect = 0.003
Identities = 53/205 (25%), Positives = 92/205 (44%), Gaps = 22/205 (10%)
Query: 458 KATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLEL 517
K AEDR KQLEE Q++ K K E++ + +KE EK E+ +K +
Sbjct: 29 KKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQ-------EKLEQAEKKATDA 81
Query: 518 SSKINNTLTECLNLIEGGV--PSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIG 575
+ + +L + L+E + + L + EAEK A K++ ++ D
Sbjct: 82 EADV-ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKD--- 137
Query: 576 LYEEAIKNGATPIQELR-KVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKMESVK 634
EE ++ +QE++ K +I +DS+R E + ++ E + EE A+ ES
Sbjct: 138 --EEKME-----LQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKC 190
Query: 635 SCLSPKEREQVTATPRIAKAEQHNY 659
L +E + VT + +A+ Y
Sbjct: 191 GDLE-EELKIVTNNLKSLEAQADKY 214
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 39.7 bits (91), Expect = 0.010
Identities = 67/305 (21%), Positives = 130/305 (42%), Gaps = 30/305 (9%)
Query: 449 TQTNPNIKKKATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEE 508
T+ + A ++ R + E+ KT + E KT I+EM +++E+
Sbjct: 1146 TELEDTLDSTAAQQELRSKREQEVNILKKTLEE---EAKTHEAQIQEMRQKHSQAVEELA 1202
Query: 509 EEKKAQLELSSKINNTLTECLNLIEG--GVPSNEILNILSSIPEAEKFAKFWICKAKLLA 566
E QLE + ++ L + +E G +NE+ +L ++E K +A+L
Sbjct: 1203 E----QLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKK--VEAQLQE 1256
Query: 567 SKGTFDVIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGITSDSLVAETSITSVEEL 626
+ F+ + + T +Q V +L S+ + +T D E+ + +EL
Sbjct: 1257 LQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQEL 1316
Query: 627 AKKMESVKSCLSPK----EREQVTATPRIAKAEQHNYPGIKLQIGPIPRINGMPEVQDMK 682
++ K LS K E E+ + ++ + E+ + ++ QI + +V DMK
Sbjct: 1317 LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKH-NLEKQIATL-----HAQVADMK 1370
Query: 683 -----FITPVRRSSRIERAVSRYPEML-QEHDLVVASLDELLEVEETKCFIFRRNEALPV 736
+ + + ++R + + E L Q H+ VA+ D+L E+TK + + + L V
Sbjct: 1371 KKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKL---EKTKTRLQQELDDLLV 1427
Query: 737 TLGFQ 741
L Q
Sbjct: 1428 DLDHQ 1432
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 39.7 bits (91), Expect = 0.010
Identities = 52/205 (25%), Positives = 88/205 (42%), Gaps = 22/205 (10%)
Query: 458 KATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLEL 517
K AEDR KQLE+ S K K EL + +K+ EK E +K +
Sbjct: 29 KKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ-------EKLELAEKKATDA 81
Query: 518 SSKINNTLTECLNLIEGGV--PSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIG 575
+ + +L + L+E + + L + EAEK A K++ S+ D
Sbjct: 82 EADV-ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKD--- 137
Query: 576 LYEEAIKNGATPIQELR-KVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKMESVK 634
EE ++ IQE++ K +I +D++R E + ++ E+ + EE A+ E K
Sbjct: 138 --EEKME-----IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEG-K 189
Query: 635 SCLSPKEREQVTATPRIAKAEQHNY 659
+E + VT + +A+ Y
Sbjct: 190 CAELEEELKTVTNNLKSLEAQAEKY 214
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 39.7 bits (91), Expect = 0.010
Identities = 52/205 (25%), Positives = 88/205 (42%), Gaps = 22/205 (10%)
Query: 458 KATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLEL 517
K AEDR KQLE+ S K K EL + +K+ EK E +K +
Sbjct: 29 KKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ-------EKLELAEKKATDA 81
Query: 518 SSKINNTLTECLNLIEGGV--PSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIG 575
+ + +L + L+E + + L + EAEK A K++ S+ D
Sbjct: 82 EADV-ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKD--- 137
Query: 576 LYEEAIKNGATPIQELR-KVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKMESVK 634
EE ++ IQE++ K +I +D++R E + ++ E+ + EE A+ E K
Sbjct: 138 --EEKME-----IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEG-K 189
Query: 635 SCLSPKEREQVTATPRIAKAEQHNY 659
+E + VT + +A+ Y
Sbjct: 190 CAELEEELKTVTNNLKSLEAQAEKY 214
>gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens]
Length = 1721
Score = 38.1 bits (87), Expect = 0.030
Identities = 59/271 (21%), Positives = 107/271 (39%), Gaps = 53/271 (19%)
Query: 191 ILTEPERKPDPKLYTRSKPKTDSYNQ-----TKNSLVPKQALGKSSVNSAVLKDRVNKQF 245
+L P +P P+++ ++P D+Y++ + S P AL K +
Sbjct: 331 LLLPPSPRPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYM------------- 377
Query: 246 VGETQSRTFPVKSQQLSRGADLARP-GVKPSRTVPSHFIRTL--SKVQSSKKPVVKNIKD 302
T S FP + +LS G P G + ++ VP H +T + S P+ ++
Sbjct: 378 ---TVSSEFP--AARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSPPL---LEK 429
Query: 303 IKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQVCI 362
V + ++P + + V + H K L+ + + +
Sbjct: 430 QTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSP 489
Query: 363 PQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDSK- 421
P C + +S+ IS P+ V +P G S N+ NN K+ +L +K
Sbjct: 490 PGNGCAIYRSEIISTAPSSWV------VP--------GPSPNEENNG----KSMSLKNKA 531
Query: 422 LKKAVPQNHFLNKTAPK---TQADVTTVNGT 449
L A+PQ + + P+ T A +T V+G+
Sbjct: 532 LDWAIPQQR--SSSCPRMGGTDAVITNVSGS 560
>gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens]
Length = 1755
Score = 38.1 bits (87), Expect = 0.030
Identities = 59/271 (21%), Positives = 107/271 (39%), Gaps = 53/271 (19%)
Query: 191 ILTEPERKPDPKLYTRSKPKTDSYNQ-----TKNSLVPKQALGKSSVNSAVLKDRVNKQF 245
+L P +P P+++ ++P D+Y++ + S P AL K +
Sbjct: 331 LLLPPSPRPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYM------------- 377
Query: 246 VGETQSRTFPVKSQQLSRGADLARP-GVKPSRTVPSHFIRTL--SKVQSSKKPVVKNIKD 302
T S FP + +LS G P G + ++ VP H +T + S P+ ++
Sbjct: 378 ---TVSSEFP--AARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSPPL---LEK 429
Query: 303 IKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQVCI 362
V + ++P + + V + H K L+ + + +
Sbjct: 430 QTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSP 489
Query: 363 PQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDSK- 421
P C + +S+ IS P+ V +P G S N+ NN K+ +L +K
Sbjct: 490 PGNGCAIYRSEIISTAPSSWV------VP--------GPSPNEENNG----KSMSLKNKA 531
Query: 422 LKKAVPQNHFLNKTAPK---TQADVTTVNGT 449
L A+PQ + + P+ T A +T V+G+
Sbjct: 532 LDWAIPQQR--SSSCPRMGGTDAVITNVSGS 560
>gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens]
Length = 1703
Score = 38.1 bits (87), Expect = 0.030
Identities = 59/271 (21%), Positives = 107/271 (39%), Gaps = 53/271 (19%)
Query: 191 ILTEPERKPDPKLYTRSKPKTDSYNQ-----TKNSLVPKQALGKSSVNSAVLKDRVNKQF 245
+L P +P P+++ ++P D+Y++ + S P AL K +
Sbjct: 331 LLLPPSPRPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYM------------- 377
Query: 246 VGETQSRTFPVKSQQLSRGADLARP-GVKPSRTVPSHFIRTL--SKVQSSKKPVVKNIKD 302
T S FP + +LS G P G + ++ VP H +T + S P+ ++
Sbjct: 378 ---TVSSEFP--AARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSPPL---LEK 429
Query: 303 IKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQVCI 362
V + ++P + + V + H K L+ + + +
Sbjct: 430 QTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSP 489
Query: 363 PQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDSK- 421
P C + +S+ IS P+ V +P G S N+ NN K+ +L +K
Sbjct: 490 PGNGCAIYRSEIISTAPSSWV------VP--------GPSPNEENNG----KSMSLKNKA 531
Query: 422 LKKAVPQNHFLNKTAPK---TQADVTTVNGT 449
L A+PQ + + P+ T A +T V+G+
Sbjct: 532 LDWAIPQQR--SSSCPRMGGTDAVITNVSGS 560
>gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens]
Length = 1721
Score = 38.1 bits (87), Expect = 0.030
Identities = 59/271 (21%), Positives = 107/271 (39%), Gaps = 53/271 (19%)
Query: 191 ILTEPERKPDPKLYTRSKPKTDSYNQ-----TKNSLVPKQALGKSSVNSAVLKDRVNKQF 245
+L P +P P+++ ++P D+Y++ + S P AL K +
Sbjct: 331 LLLPPSPRPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYM------------- 377
Query: 246 VGETQSRTFPVKSQQLSRGADLARP-GVKPSRTVPSHFIRTL--SKVQSSKKPVVKNIKD 302
T S FP + +LS G P G + ++ VP H +T + S P+ ++
Sbjct: 378 ---TVSSEFP--AARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSPPL---LEK 429
Query: 303 IKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQVCI 362
V + ++P + + V + H K L+ + + +
Sbjct: 430 QTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSGSEIPKETLSP 489
Query: 363 PQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDSK- 421
P C + +S+ IS P+ V +P G S N+ NN K+ +L +K
Sbjct: 490 PGNGCAIYRSEIISTAPSSWV------VP--------GPSPNEENNG----KSMSLKNKA 531
Query: 422 LKKAVPQNHFLNKTAPK---TQADVTTVNGT 449
L A+PQ + + P+ T A +T V+G+
Sbjct: 532 LDWAIPQQR--SSSCPRMGGTDAVITNVSGS 560
>gi|33457320 UBX domain containing 4 [Homo sapiens]
Length = 259
Score = 38.1 bits (87), Expect = 0.030
Identities = 53/254 (20%), Positives = 102/254 (40%), Gaps = 38/254 (14%)
Query: 241 VNKQFVGETQSRTFPVKSQQLSRGADLARPGVKPSRTVPSHFIRTLSKVQSSKKPVVKNI 300
+ +++V ET S P+ + Q S + ++ V S + +S + K+ V
Sbjct: 10 IKEEWVCETGSDNQPLGNNQQSNCEYFVDSLFEEAQKVSS---KCVSPAEQKKQVDV--- 63
Query: 301 KDIKVNRSQYERPNETKIRSYPVTEQRVKHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQV 360
+IK+ ++ + ++ + S ++Q + K PS LQG ++ ++K + K +++
Sbjct: 64 -NIKLWKNGFTVNDDFRSYSDGASQQFLNSIKKGELPSELQGIFDKEEVDVKVEDKKNEI 122
Query: 361 CIPQTSCVLQKSKAISQRPNLTVGRFNSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDS 420
C+ +K + Q + R SA P S N NK+N
Sbjct: 123 CL--------STKPVFQPFSGQGHRLGSATPKIVSKAKNIEVENKNN------------- 161
Query: 421 KLKKAVPQNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQLEEWQKSKGKTYK 480
AVP LN P T + NG + I +K R ++++ + + +
Sbjct: 162 --LSAVP----LNNLEPITNIQIWLANGKR----IVQKFNITHRVSHIKDFIEKYQGSQR 211
Query: 481 RPPMELKTKRKVIK 494
PP L T V++
Sbjct: 212 SPPFSLATALPVLR 225
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 37.4 bits (85), Expect = 0.051
Identities = 46/177 (25%), Positives = 77/177 (43%), Gaps = 21/177 (11%)
Query: 458 KATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLEL 517
K AEDR KQLE+ S K K EL + +K+ EK E +K +
Sbjct: 29 KKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ-------EKLELAEKKATDA 81
Query: 518 SSKINNTLTECLNLIEGGV--PSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIG 575
+ + +L + L+E + + L + EAEK A K++ S+ D
Sbjct: 82 EADV-ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKD--- 137
Query: 576 LYEEAIKNGATPIQELR-KVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKME 631
EE ++ IQE++ K +I +D++R E + ++ E+ + EE A+ E
Sbjct: 138 --EEKME-----IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSE 187
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 37.4 bits (85), Expect = 0.051
Identities = 46/177 (25%), Positives = 77/177 (43%), Gaps = 21/177 (11%)
Query: 458 KATAEDRRKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLEL 517
K AEDR KQLE+ S K K EL + +K+ EK E +K +
Sbjct: 29 KKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQ-------EKLELAEKKATDA 81
Query: 518 SSKINNTLTECLNLIEGGV--PSNEILNILSSIPEAEKFAKFWICKAKLLASKGTFDVIG 575
+ + +L + L+E + + L + EAEK A K++ S+ D
Sbjct: 82 EADV-ASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKD--- 137
Query: 576 LYEEAIKNGATPIQELR-KVVLNILQDSNRTTEGITSDSLVAETSITSVEELAKKME 631
EE ++ IQE++ K +I +D++R E + ++ E+ + EE A+ E
Sbjct: 138 --EEKME-----IQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSE 187
>gi|4557719 DNA ligase I [Homo sapiens]
Length = 919
Score = 37.0 bits (84), Expect = 0.067
Identities = 70/302 (23%), Positives = 122/302 (40%), Gaps = 72/302 (23%)
Query: 16 QRKLQEYLAAKGKLKSQNTKPYLKSKNNC-QNQPPSKSTIRPKNDVTNHVVLPVK-PKRS 73
QR + + K + K++ KP ++ N+ + +PP K+ ++ N V + PVK P R
Sbjct: 2 QRSIMSFFHPKKEGKAK--KPEKEASNSSRETEPPPKAALKEWNGVVSESDSPVKRPGRK 59
Query: 74 ISIKLQPRPPNTAGSQKPK-LEPPKLLGKRLTSECVSSNPYSKPSSKSFQQCEAGSSTTG 132
+ R + G ++ + L P K G++ +C +P P + + A S T
Sbjct: 60 AA-----RVLGSEGEEEDEALSPAK--GQKPALDCSQVSP---PRPATSPENNASLSDTS 109
Query: 133 ELSRKPVGSLNIEQLKTTKQQLTDQGNGKCIDFMNNIHVENESLDNFLK--------ETN 184
+ P G I + +T ++QL + + ++E D K ET
Sbjct: 110 PMDSSPSG---IPKRRTARKQLPKR------TIQEVLEEQSEDEDREAKRKKEEEEEETP 160
Query: 185 KENL--LDILTEPERKPDPKLYTRSKPKTDSYNQTKNSLVPKQALGKSSVNSAVLKDRVN 242
KE+L ++ TE E + + T KP S +T P +++ + V
Sbjct: 161 KESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAET-----PTESVSEPEV--------AT 207
Query: 243 KQFVGETQSRTFPVKSQQLSRGADLARPGVKPSRTVPSHFIRTLSKVQSSKKPVVKNIKD 302
KQ + E + +T KP R P +TLS + +KP VK K+
Sbjct: 208 KQELQEEEEQT-------------------KPPRRAP----KTLSSFFTPRKPAVK--KE 242
Query: 303 IK 304
+K
Sbjct: 243 VK 244
>gi|56788356 tuftelin interacting protein 11 [Homo sapiens]
Length = 837
Score = 37.0 bits (84), Expect = 0.067
Identities = 46/204 (22%), Positives = 84/204 (41%), Gaps = 30/204 (14%)
Query: 445 TVNGTQTNPNIKKKATAEDR-RKQLEEWQKSKGKTYKRPPM------ELKTKRKVIKEM- 496
T Q P + + AE+ +K+L +W+K + K+P ELK K ++ K++
Sbjct: 198 TTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLT 257
Query: 497 ----NISFWKSIEKEEEEKKAQLELSSKINNTLTECLNLIEGGVPSNEILNILSSIPEAE 552
+S K I+ E+K S ++ N+ + G+P +P++
Sbjct: 258 APQKELSQVKVIDMTGREQKVYYSYSQ-----ISHKHNVPDDGLPLQS-----QQLPQSG 307
Query: 553 KFAKFWICKAKLLASKGTFDVIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGITSD 612
K AK L +I L E+ I +Q R +V+N+ + + TE + +
Sbjct: 308 KEAKAPGFALPELEHNLQL-LIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMTEVLDHE 366
Query: 613 SLVAETSITSVEELAKKMESVKSC 636
V + L+K +E V+ C
Sbjct: 367 ERV-------ISNLSKVLEMVEEC 383
>gi|8393259 tuftelin interacting protein 11 [Homo sapiens]
Length = 837
Score = 37.0 bits (84), Expect = 0.067
Identities = 46/204 (22%), Positives = 84/204 (41%), Gaps = 30/204 (14%)
Query: 445 TVNGTQTNPNIKKKATAEDR-RKQLEEWQKSKGKTYKRPPM------ELKTKRKVIKEM- 496
T Q P + + AE+ +K+L +W+K + K+P ELK K ++ K++
Sbjct: 198 TTQSMQDFPVVDSEEEAEEEFQKELSQWRKDPSGSKKKPKYSYKTVEELKAKGRISKKLT 257
Query: 497 ----NISFWKSIEKEEEEKKAQLELSSKINNTLTECLNLIEGGVPSNEILNILSSIPEAE 552
+S K I+ E+K S ++ N+ + G+P +P++
Sbjct: 258 APQKELSQVKVIDMTGREQKVYYSYSQ-----ISHKHNVPDDGLPLQS-----QQLPQSG 307
Query: 553 KFAKFWICKAKLLASKGTFDVIGLYEEAIKNGATPIQELRKVVLNILQDSNRTTEGITSD 612
K AK L +I L E+ I +Q R +V+N+ + + TE + +
Sbjct: 308 KEAKAPGFALPELEHNLQL-LIDLTEQEIIQNDRQLQYERDMVVNLFHELEKMTEVLDHE 366
Query: 613 SLVAETSITSVEELAKKMESVKSC 636
V + L+K +E V+ C
Sbjct: 367 ERV-------ISNLSKVLEMVEEC 383
>gi|23503243 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 8 [Homo sapiens]
Length = 392
Score = 37.0 bits (84), Expect = 0.067
Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 12/138 (8%)
Query: 484 MELKTKRKVIKEMNISFWKS-IEKEEEEKKAQLELSSKINNTLTECLNLIEGGVPSNEIL 542
+E K KR ++ FW++ ++ E+E +K + +I +TEC N ++ + +
Sbjct: 209 LEQKIKRNDVEIEEEEFWENELQIEQENEKQLKDQLQEIRQKITECENKLKDYLAQ---I 265
Query: 543 NILSSIPEAEKFAKFWI--------CKAKLLASKGTFDVIGLYEEAIKNGATPIQELRKV 594
+ S EAEK + K K+ KG D+ G ++NG ++
Sbjct: 266 RTMESGLEAEKLQREVQEAQVNEEEVKGKIGKVKGEIDIQGQQSLRLENGIKAVERSLGQ 325
Query: 595 VLNILQDSNRTTEGITSD 612
LQD + E +T +
Sbjct: 326 ATKRLQDKEQELEQLTKE 343
>gi|32528306 replication factor C large subunit [Homo sapiens]
Length = 1147
Score = 36.6 bits (83), Expect = 0.087
Identities = 105/548 (19%), Positives = 195/548 (35%), Gaps = 66/548 (12%)
Query: 14 ERQRKLQEYLAAKGKLKSQNTKPYLKSKNNCQNQPPSKSTIRPKNDVTNHVVLPVK---- 69
E+ + +E L AK +K K + Q QP K I +D + L VK
Sbjct: 25 EKTKSDEETLKAKKGIKEIKVNSSRKEDDFKQKQPSKKKRIIYDSDSESEETLQVKNAKK 84
Query: 70 -----PKRSISIKLQPRPPNTAGSQ---------KPKLEPPKLLGKRLTSECVSSN---- 111
P S K+ + P T S+ K K G+ S +SN
Sbjct: 85 PPEKLPVSSKPGKISRQDPVTYISETDEEDDFMCKKAASKSKENGRSTNSHLGTSNMKKN 144
Query: 112 -PYSKPSSKSFQQCEA---------GSSTTGELSRKPVGSLNIEQLKTTKQQ-LTDQGNG 160
+K +K + G+ + ++K V S E + T + L D+
Sbjct: 145 EENTKTKNKPLSPIKLTPTSVLDYFGTGSVQRSNKKMVASKRKELSQNTDESGLNDEAIA 204
Query: 161 KCIDFMNNIHVENESLDNFLKETNKENLLDILTEPERKPDPKLYTRSKPKTDSYNQTKNS 220
K + + +E + ++ E L + +P K + ++++ + +
Sbjct: 205 KQLQLDEDAELERQLHED-------EEFARTLAMLDEEPKTKKARKDTEAGETFSSVQAN 257
Query: 221 LVPKQALG-KSSVNSAVLKDRVNKQFVGETQSRTFPVKSQQLSRGADLARPGVKPSRTVP 279
L + V +A + D K + QS+ K Q + + G S
Sbjct: 258 LSKAEKHKYPHKVKTAQVSDE-RKSYSPRKQSKYESSKESQQHSKSSADKIGEVSSPKAS 316
Query: 280 SHFIRTLSKVQSSKK---PVVKNIKDIKVN-RSQYERPNETKIRSYPVTEQRV------- 328
S K +SS K PV K+ + + + + P +TK S P ++ V
Sbjct: 317 SKLAIMKRKEESSYKEIEPVASKRKENAIKLKGETKTPKKTK--SSPAKKESVSPEDSEK 374
Query: 329 KHTKPRTYPSLLQGEYNNRHPNIKQDQKSSQVCIPQTSCVLQKSKAISQRPNLT--VGRF 386
K T + Y S L E + K+ K ++ C+ V+ +R + R+
Sbjct: 375 KRTNYQAYRSYLNRE-GPKALGSKEIPKGAENCLEGLIFVITGVLESIERDEAKSLIERY 433
Query: 387 NSAIPSTPSIRPNGTSGNKHNNNGFQQKAQTLDSKLKKAVPQNHFLN--KTAPKTQADVT 444
+ S + N + + KA L +K+ + ++ LN +T P ++
Sbjct: 434 GGKVTGNVSKKTNYLVMGRDSGQSKSDKAAALGTKI---IDEDGLLNLIRTMPGKKSKYE 490
Query: 445 TVNGTQTNPNIKKKATAEDR---RKQLEEWQKSKGKTYKRPPMELKTKRKVIKEMNISFW 501
T+ K + T + ++++ +K RP + + K IK+ FW
Sbjct: 491 IAVETEMKKESKLERTPQKNVQGKRKISPSKKESESKKSRPTSKRDSLAKTIKKETDVFW 550
Query: 502 KSIEKEEE 509
KS++ +E+
Sbjct: 551 KSLDFKEQ 558
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 36.2 bits (82), Expect = 0.11
Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Query: 412 QQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQLEEW 471
++K ++K K + +K PK +T P KKK +D+RK+ ++
Sbjct: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
Query: 472 QKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLE 516
+K K + ++ E ++K+K +E + +K+EE+ K Q E
Sbjct: 72 RKKKDE--EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 36.2 bits (82), Expect = 0.11
Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Query: 412 QQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAEDRRKQLEEW 471
++K ++K K + +K PK +T P KKK +D+RK+ ++
Sbjct: 12 EEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKE 71
Query: 472 QKSKGKTYKRPPMELKTKRKVIKEMNISFWKSIEKEEEEKKAQLE 516
+K K + ++ E ++K+K +E + +K+EE+ K Q E
Sbjct: 72 RKKKDE--EKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQE 114
>gi|94536834 PAP associated domain containing 5 isoform a [Homo
sapiens]
Length = 489
Score = 36.2 bits (82), Expect = 0.11
Identities = 36/147 (24%), Positives = 62/147 (42%), Gaps = 9/147 (6%)
Query: 12 VEERQRKLQEYLAAKGKLKSQNTKPYLKSKNNCQNQPPSKS--TIRPKNDVTNHVVLPVK 69
+++ L E A GK +S+ ++ K +N + P S S T +DV +
Sbjct: 326 LDKCNNNLSEENEALGKCRSKTSESLSKHSSNSSSGPVSSSSATQSSSSDVDSDATPCKT 385
Query: 70 PKRSISIKLQPRPPNTAGSQKPKLEPPKLLGK----RLTSECVSSNPYSKPSSKSFQQCE 125
PK+ + +P N GSQ LE + +GK + T+ S+N S++ F+
Sbjct: 386 PKQLLC---RPSTGNRVGSQDVSLESSQAVGKMQSTQTTNTSNSTNKSQHGSARLFRSSS 442
Query: 126 AGSSTTGELSRKPVGSLNIEQLKTTKQ 152
G T + S + + Q K+ Q
Sbjct: 443 KGFQGTTQTSHGSLMTNKQHQGKSNNQ 469
>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
Length = 248
Score = 35.4 bits (80), Expect = 0.19
Identities = 28/106 (26%), Positives = 47/106 (44%), Gaps = 7/106 (6%)
Query: 403 GNKHNNNGFQQKAQTLDSKLKKAVPQNHFLNKTAPKTQADVTTVNGTQTNPNIKKKATAE 462
G K ++K +T K KK + KT +T TT T T K+K +
Sbjct: 26 GRKKKTTKKKKKKKTTMKKKKKTTTKKKTTTKTKKRT---TTTKKTTTTTTKEKEKEKEK 82
Query: 463 DRRKQLE-EWQKSKGKTYKRPPMELKTKRKV---IKEMNISFWKSI 504
++ K+ E E +K K K K+ + K K+K+ + + I+ W +
Sbjct: 83 EKEKEKEKEKEKEKEKKKKKKKKKKKKKKKLNAKVCGLEIASWSEM 128
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 35.4 bits (80), Expect = 0.19
Identities = 20/102 (19%), Positives = 52/102 (50%), Gaps = 18/102 (17%)
Query: 438 KTQADVTTVNGTQTNPNIKKKATAEDRRKQLEE-----WQKSKGKTYKRPPMELKTKRKV 492
++ + ++ ++ T + + ++ ED ++QLE+ ++ K + ++R +EL+ +R+
Sbjct: 312 RSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQA 371
Query: 493 IKEMNISFWKSI-------------EKEEEEKKAQLELSSKI 521
+ E + + E++E+E+K QLEL ++
Sbjct: 372 LLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQL 413
Score = 30.4 bits (67), Expect = 6.2
Identities = 23/91 (25%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 432 LNKTAPKTQADVTTVNGTQTNPNIKKKATA--EDRRKQLE---EWQKSKGKTYKRPPMEL 486
L K P T D N + N ++K+ A E +RK+ E + ++++ + +R E
Sbjct: 342 LEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQ 401
Query: 487 KTKRKVIKEMNISFWKSIEKE-EEEKKAQLE 516
+ KR++ E + + +E++ EEE++ ++E
Sbjct: 402 ERKRQLELEKQLEKQRELERQREEERRKEIE 432
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 35.4 bits (80), Expect = 0.19
Identities = 20/102 (19%), Positives = 52/102 (50%), Gaps = 18/102 (17%)
Query: 438 KTQADVTTVNGTQTNPNIKKKATAEDRRKQLEE-----WQKSKGKTYKRPPMELKTKRKV 492
++ + ++ ++ T + + ++ ED ++QLE+ ++ K + ++R +EL+ +R+
Sbjct: 312 RSGSGISVISSTSVDQRLPEEPVLEDEQQQLEKKLPVTFEDKKRENFERGNLELEKRRQA 371
Query: 493 IKEMNISFWKSI-------------EKEEEEKKAQLELSSKI 521
+ E + + E++E+E+K QLEL ++
Sbjct: 372 LLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQL 413
Score = 30.4 bits (67), Expect = 6.2
Identities = 23/91 (25%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 432 LNKTAPKTQADVTTVNGTQTNPNIKKKATA--EDRRKQLE---EWQKSKGKTYKRPPMEL 486
L K P T D N + N ++K+ A E +RK+ E + ++++ + +R E
Sbjct: 342 LEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQ 401
Query: 487 KTKRKVIKEMNISFWKSIEKE-EEEKKAQLE 516
+ KR++ E + + +E++ EEE++ ++E
Sbjct: 402 ERKRQLELEKQLEKQRELERQREEERRKEIE 432
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 35.4 bits (80), Expect = 0.19
Identities = 73/352 (20%), Positives = 137/352 (38%), Gaps = 42/352 (11%)
Query: 7 TAAAAVEERQRKLQEYLAAKGKLKSQNTKPYLKSKNNCQ--NQPPSKSTI------RPKN 58
T A+ +E ++ L+E + KG + ++T L++KN Q N+ K + R N
Sbjct: 5966 TKIASEKEYRKDLEESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLN 6025
Query: 59 DVTNHVVLPVKPKRSISIKLQPRPPNTAGSQKPK----LEPPKLLGKRLTSECVSSNPYS 114
+ N ++ + + I Q + +A +K ++ P+++ + S Y
Sbjct: 6026 AMANETPDFMRARNATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYK 6085
Query: 115 KPSSKSFQQCEAGSSTTGELSRKPVGSLNIEQLKTTKQQLTDQGNGKCIDFMNNIHVENE 174
+ + KS E T E+ R N L Q D N K I V +
Sbjct: 6086 EDAEKSMSYYETVLDTP-EIQRVRENQKNFSLL----QYQCDLKNSK-----GKITVVQD 6135
Query: 175 SLDNFLKETNKENLLDILTEPERKPDPKLYTRSKPKTDSYNQTK---NSLVPKQALGKSS 231
+ + + N++N +L + + P + P+ QT+ +S+ K+A+G+ +
Sbjct: 6136 TPEILRVKENQKNFSSVLYKEDVSPGTAI--GKTPEMMRVKQTQDHISSVKYKEAIGQGT 6193
Query: 232 VNSAVLKDRVNKQFVGETQSRTFPVK-SQQLSRG-ADLARPGVKPSRTVPSHFIRTLSKV 289
+ D + V ETQ V + L G P ++ + +F L K
Sbjct: 6194 ----PIPDLPEVKRVKETQKHISSVMYKENLGTGIPTTVTPEIERVKRNQENFSSVLYKE 6249
Query: 290 QSSK---KPVVKNIKDIKVNRSQYE----RPNETKIRSYPVTE--QRVKHTK 332
K P+ ++ +K N+ + + N K VT +RVKH +
Sbjct: 6250 NLGKGIPTPITPEMERVKRNQENFSSVLYKENMGKGTPLAVTPEMERVKHNQ 6301
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,197,940
Number of Sequences: 37866
Number of extensions: 1356126
Number of successful extensions: 5265
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 199
Number of HSP's that attempted gapping in prelim test: 5037
Number of HSP's gapped (non-prelim): 404
length of query: 745
length of database: 18,247,518
effective HSP length: 110
effective length of query: 635
effective length of database: 14,082,258
effective search space: 8942233830
effective search space used: 8942233830
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.