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Search of human proteins with 167466175
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
(824 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 1658 0.0
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 1652 0.0
gi|239758107 PREDICTED: similar to Cell division cycle 27 homolo... 130 5e-30
gi|239750229 PREDICTED: similar to Cell division cycle 27 homolo... 130 5e-30
gi|118402596 cell division cycle protein 23 [Homo sapiens] 123 6e-28
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 82 2e-15
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 82 2e-15
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 82 2e-15
gi|118402578 anaphase-promoting complex, subunit 6 [Homo sapiens] 80 6e-15
gi|118402580 anaphase-promoting complex, subunit 6 [Homo sapiens] 80 6e-15
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 77 7e-14
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 77 7e-14
gi|212549736 anaphase-promoting complex subunit 7 isoform a [Hom... 68 3e-11
gi|83415184 transmembrane and tetratricopeptide repeat containin... 63 1e-09
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 58 4e-08
gi|118766328 transmembrane and tetratricopeptide repeat containi... 58 4e-08
gi|118766330 transmembrane and tetratricopeptide repeat containi... 58 4e-08
gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap... 55 2e-07
gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sap... 55 2e-07
gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sap... 55 2e-07
gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sap... 55 2e-07
gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapi... 55 2e-07
gi|224809432 transmembrane and tetratricopeptide repeat containi... 55 2e-07
gi|212549738 anaphase-promoting complex subunit 7 isoform b [Hom... 55 3e-07
gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 54 5e-07
gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 54 8e-07
gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo sa... 52 2e-06
gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo sa... 52 2e-06
gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo sa... 52 2e-06
gi|54607135 translocase of outer mitochondrial membrane 70 homol... 52 2e-06
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 1658 bits (4294), Expect = 0.0
Identities = 824/824 (100%), Positives = 824/824 (100%)
Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60
MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL
Sbjct: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60
Query: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120
LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL
Sbjct: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120
Query: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180
LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL
Sbjct: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180
Query: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240
PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI
Sbjct: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240
Query: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300
SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN
Sbjct: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300
Query: 301 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP 360
YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP
Sbjct: 301 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP 360
Query: 361 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ 420
QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ
Sbjct: 361 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ 420
Query: 421 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN 480
PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN
Sbjct: 421 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN 480
Query: 481 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540
CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS
Sbjct: 481 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540
Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600
TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY
Sbjct: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600
Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660
AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK
Sbjct: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660
Query: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720
ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK
Sbjct: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720
Query: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780
SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID
Sbjct: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780
Query: 781 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824
KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF
Sbjct: 781 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 1652 bits (4277), Expect = 0.0
Identities = 824/830 (99%), Positives = 824/830 (99%), Gaps = 6/830 (0%)
Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60
MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL
Sbjct: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60
Query: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120
LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL
Sbjct: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120
Query: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180
LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL
Sbjct: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180
Query: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240
PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI
Sbjct: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240
Query: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300
SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN
Sbjct: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300
Query: 301 YTNTPPVIDVPSTGAPSKK------SVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGP 354
YTNTPPVIDVPSTGAPSKK SVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGP
Sbjct: 301 YTNTPPVIDVPSTGAPSKKTFRVLQSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGP 360
Query: 355 QTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTN 414
QTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTN
Sbjct: 361 QTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTN 420
Query: 415 KGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYL 474
KGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYL
Sbjct: 421 KGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYL 480
Query: 475 ALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVE 534
ALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVE
Sbjct: 481 ALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVE 540
Query: 535 GMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAI 594
GMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAI
Sbjct: 541 GMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAI 600
Query: 595 QVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLA 654
QVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLA
Sbjct: 601 QVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLA 660
Query: 655 EMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLF 714
EMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLF
Sbjct: 661 EMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLF 720
Query: 715 ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQ 774
ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQ
Sbjct: 721 ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQ 780
Query: 775 IKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824
IKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF
Sbjct: 781 IKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 830
>gi|239758107 PREDICTED: similar to Cell division cycle 27 homolog
(S. cerevisiae) [Homo sapiens]
Length = 70
Score = 130 bits (327), Expect = 5e-30
Identities = 62/70 (88%), Positives = 64/70 (91%)
Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60
M VLQEPVQAAIWQALNHYAYRD VFLAE L+AEVHSEEA+FLLATC YR GKAYKAYRL
Sbjct: 1 MMVLQEPVQAAIWQALNHYAYRDGVFLAEHLHAEVHSEEAMFLLATCSYRPGKAYKAYRL 60
Query: 61 LKGHSCTTPQ 70
LKGHSC TPQ
Sbjct: 61 LKGHSCPTPQ 70
>gi|239750229 PREDICTED: similar to Cell division cycle 27 homolog
(S. cerevisiae) [Homo sapiens]
Length = 70
Score = 130 bits (327), Expect = 5e-30
Identities = 62/70 (88%), Positives = 64/70 (91%)
Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60
M VLQEPVQAAIWQALNHYAYRD VFLAE L+AEVHSEEA+FLLATC YR GKAYKAYRL
Sbjct: 1 MMVLQEPVQAAIWQALNHYAYRDGVFLAEHLHAEVHSEEAMFLLATCSYRPGKAYKAYRL 60
Query: 61 LKGHSCTTPQ 70
LKGHSC TPQ
Sbjct: 61 LKGHSCPTPQ 70
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 123 bits (309), Expect = 6e-28
Identities = 63/191 (32%), Positives = 109/191 (57%)
Query: 498 TGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSK 557
+ +++ QI AY + + +A IF+E+R+ + YR+E M+ +S L+ LS L+
Sbjct: 262 SSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAH 321
Query: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEEL 617
+L ++DK E C GN +SL+ +H+ A +FQRA++++P Y A+TL+GHE++ +
Sbjct: 322 NLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNT 381
Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677
A+ +R+AI VN R Y AWYGLG Y + ++++A + P S +L +G
Sbjct: 382 SAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGE 441
Query: 678 VQHALKKSEKA 688
L + +A
Sbjct: 442 CYEKLNQLVEA 452
Score = 38.5 bits (88), Expect = 0.026
Identities = 66/292 (22%), Positives = 107/292 (36%), Gaps = 44/292 (15%)
Query: 505 IGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDK 564
+ +AYF++ EY +A + Y + +YS L +K KD +D
Sbjct: 89 LAKAYFDVKEYDRAAHFLHGCNSKKAYF---LYMYSRYLSGEKK--------KDDETVDS 137
Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624
P N RE + + +A ++D Y Y ++ + L +E A+ F
Sbjct: 138 LGPLEKGQVKN--EALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKE---AIDVF 192
Query: 625 RNAIRVNPRHYNAW-------------------------YGLGMIYYKQEKFSLAEMHFQ 659
A V P H+ AW + L IY + + A +Q
Sbjct: 193 VEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQ 252
Query: 660 KALDIN-PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEK 718
+D+ +SS ++ I V H ++ +KAL N+ DP + S L
Sbjct: 253 NLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYR-IENMDTFSNLLYVRS 311
Query: 719 YKSALQEL-EELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769
KS L L L +I +IG Y Q A + F A+ L+P+
Sbjct: 312 MKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPR 363
Score = 35.4 bits (80), Expect = 0.22
Identities = 33/177 (18%), Positives = 66/177 (37%), Gaps = 16/177 (9%)
Query: 503 CQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDM 562
C IG Y S++ +A F ++ + + ++ A + ++
Sbjct: 335 CVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV 394
Query: 563 DKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALA 622
+K AW G + + + + +++RA Q+ PN + LG + +L +A
Sbjct: 395 NKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKK 454
Query: 623 CFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQ 679
C+ A Y +G + K LA++H Q + C+I +Q
Sbjct: 455 CYWRA-----------YAVGDV-EKMALVKLAKLHEQ----LTESEQAAQCYIKYIQ 495
>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 82.0 bits (201), Expect = 2e-15
Identities = 52/194 (26%), Positives = 99/194 (51%), Gaps = 8/194 (4%)
Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633
GN F+ ++ + A+K A + N + +GH+ A+ +++AI +NP+
Sbjct: 1423 GNNFAAMQDINAAMKISTTA-EFLTNRGVIHEFMGHK-------QNAMKDYQDAITLNPK 1474
Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693
+ A++ G IY+ +FS A +F KAL +P++ +L + + LKK E+A +
Sbjct: 1475 YSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFA 1534
Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753
I P F+RA + ++Y+ A ++L + + P ++LVY KV K+G
Sbjct: 1535 NVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLI 1594
Query: 754 HLALMNFSWAMDLD 767
A+ +++ A+DL+
Sbjct: 1595 EEAMADYNQALDLE 1608
Score = 65.5 bits (158), Expect = 2e-10
Identities = 58/221 (26%), Positives = 93/221 (42%), Gaps = 4/221 (1%)
Query: 572 AAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH---EFVLTEELDKALACFRNAI 628
A C E + A+ FF A++++P + AY G+ E+ E +A F A+
Sbjct: 1309 ATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKAL 1368
Query: 629 RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688
+NP + A G Q KF A HF A+D +P++ + VV + + A
Sbjct: 1369 HINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAA 1428
Query: 689 LDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 748
+ +N A+ I F K ++A+++ ++ + PK SL YF G +Y
Sbjct: 1429 MQDINAAMKISTTAEFLTNRGVIHEFMGHK-QNAMKDYQDAITLNPKYSLAYFNAGNIYF 1487
Query: 749 KLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEE 789
Q A FS A+ DP+ + AI L EE
Sbjct: 1488 HHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEE 1528
Score = 59.7 bits (143), Expect = 1e-08
Identities = 71/315 (22%), Positives = 126/315 (40%), Gaps = 51/315 (16%)
Query: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556
N G + ++G+ F L ++ QA I R G ++T + H + + ++
Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALIS---------RTNGSLCHATAMCHHRINEFEEAVN 1325
Query: 557 KDLTDMDKNSP---EAWCAAGNCFSLQREHDIAIKF----FQRAIQVDPNYAYAYTLLGH 609
T K +P +A+ GN + ++ HD A K F +A+ ++P Y A G+
Sbjct: 1326 F-FTWALKINPCFLDAYVGRGNSY-MEYGHDEATKQAQKDFLKALHINPAYIKARISFGY 1383
Query: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGL---------------------------- 641
+ KA F AI +P++Y A+ G
Sbjct: 1384 NLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAE 1443
Query: 642 -----GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696
G+I+ A +Q A+ +NP+ S+ + G + ++ +A D +KA+
Sbjct: 1444 FLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKAL 1503
Query: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756
DP+N +RA +KY+ A ++ + + P + VYF Y L Q LA
Sbjct: 1504 KFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELA 1563
Query: 757 LMNFSWAMDLDPKGA 771
+ + A+ L P A
Sbjct: 1564 EEDLNKALSLKPNDA 1578
Score = 52.4 bits (124), Expect = 2e-06
Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 4/199 (2%)
Query: 552 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 611
+ +L++++ D K A+C G + + A+ QR I ++P + AY +
Sbjct: 902 VKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIY 961
Query: 612 VLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671
+ +++++AL + N + A+ IY ++ +LA +++ +A+ P + +
Sbjct: 962 LFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADI 1021
Query: 672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ 731
G + K A+D +K I DPK R NE + +A+++ L
Sbjct: 1022 YFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
Query: 732 IVPKESLV---YFLIGKVY 747
I + S Y L+ K Y
Sbjct: 1081 IDHQNSQARGQYLLMMKYY 1099
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 10/152 (6%)
Query: 557 KDLTDMDKNSPE---AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
KD D +P+ A+ AGN + R+ A +F +A++ DP Y +
Sbjct: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522
Query: 614 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL- 672
++ ++A F N I P ++ YY +++ LAE KAL + P +++
Sbjct: 1523 LKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN 1582
Query: 673 ------CHIGVVQHALKKSEKALDTLNKAIVI 698
IG+++ A+ +ALD + A VI
Sbjct: 1583 FRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 4/128 (3%)
Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704
YY+ E L E + D + C G + L K + A++ L + I+++P
Sbjct: 897 YYESEVKILTE----EINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLN 952
Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 764
+HR + +K AL +L + + + Y ++Y+ LA++N++ A+
Sbjct: 953 AYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAI 1012
Query: 765 DLDPKGAN 772
P A+
Sbjct: 1013 KSTPTDAD 1020
Score = 39.3 bits (90), Expect = 0.015
Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 21/194 (10%)
Query: 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT 542
E IN + P+ Y C+ G Y +L + A V +E ++
Sbjct: 907 EEINDKTKYPAFAY------CRRGAIYRKLGKLQSAMNDLQRVILLE-------PLFLNA 953
Query: 543 LWHLQKDVALS-VLSKDLTDMD------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595
WH +++ L D++ KN+ EA+ + + +++ +AI + +AI+
Sbjct: 954 YWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIK 1013
Query: 596 VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655
P A Y G + +T ++ A+ F I +P+ +A G+ Y + E + A
Sbjct: 1014 STPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAI 1072
Query: 656 MHFQKALDINPQSS 669
F L+I+ Q+S
Sbjct: 1073 EDFTALLNIDHQNS 1086
>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
sapiens]
Length = 1614
Score = 82.0 bits (201), Expect = 2e-15
Identities = 52/194 (26%), Positives = 99/194 (51%), Gaps = 8/194 (4%)
Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633
GN F+ ++ + A+K A + N + +GH+ A+ +++AI +NP+
Sbjct: 1423 GNNFAAMQDINAAMKISTTA-EFLTNRGVIHEFMGHK-------QNAMKDYQDAITLNPK 1474
Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693
+ A++ G IY+ +FS A +F KAL +P++ +L + + LKK E+A +
Sbjct: 1475 YSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFA 1534
Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753
I P F+RA + ++Y+ A ++L + + P ++LVY KV K+G
Sbjct: 1535 NVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLI 1594
Query: 754 HLALMNFSWAMDLD 767
A+ +++ A+DL+
Sbjct: 1595 EEAMADYNQALDLE 1608
Score = 65.5 bits (158), Expect = 2e-10
Identities = 58/221 (26%), Positives = 93/221 (42%), Gaps = 4/221 (1%)
Query: 572 AAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH---EFVLTEELDKALACFRNAI 628
A C E + A+ FF A++++P + AY G+ E+ E +A F A+
Sbjct: 1309 ATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKAL 1368
Query: 629 RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688
+NP + A G Q KF A HF A+D +P++ + VV + + A
Sbjct: 1369 HINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAA 1428
Query: 689 LDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 748
+ +N A+ I F K ++A+++ ++ + PK SL YF G +Y
Sbjct: 1429 MQDINAAMKISTTAEFLTNRGVIHEFMGHK-QNAMKDYQDAITLNPKYSLAYFNAGNIYF 1487
Query: 749 KLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEE 789
Q A FS A+ DP+ + AI L EE
Sbjct: 1488 HHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEE 1528
Score = 59.7 bits (143), Expect = 1e-08
Identities = 71/315 (22%), Positives = 126/315 (40%), Gaps = 51/315 (16%)
Query: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556
N G + ++G+ F L ++ QA I R G ++T + H + + ++
Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALIS---------RTNGSLCHATAMCHHRINEFEEAVN 1325
Query: 557 KDLTDMDKNSP---EAWCAAGNCFSLQREHDIAIKF----FQRAIQVDPNYAYAYTLLGH 609
T K +P +A+ GN + ++ HD A K F +A+ ++P Y A G+
Sbjct: 1326 F-FTWALKINPCFLDAYVGRGNSY-MEYGHDEATKQAQKDFLKALHINPAYIKARISFGY 1383
Query: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGL---------------------------- 641
+ KA F AI +P++Y A+ G
Sbjct: 1384 NLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAE 1443
Query: 642 -----GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696
G+I+ A +Q A+ +NP+ S+ + G + ++ +A D +KA+
Sbjct: 1444 FLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKAL 1503
Query: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756
DP+N +RA +KY+ A ++ + + P + VYF Y L Q LA
Sbjct: 1504 KFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELA 1563
Query: 757 LMNFSWAMDLDPKGA 771
+ + A+ L P A
Sbjct: 1564 EEDLNKALSLKPNDA 1578
Score = 52.4 bits (124), Expect = 2e-06
Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 4/199 (2%)
Query: 552 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 611
+ +L++++ D K A+C G + + A+ QR I ++P + AY +
Sbjct: 902 VKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIY 961
Query: 612 VLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671
+ +++++AL + N + A+ IY ++ +LA +++ +A+ P + +
Sbjct: 962 LFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADI 1021
Query: 672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ 731
G + K A+D +K I DPK R NE + +A+++ L
Sbjct: 1022 YFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
Query: 732 IVPKESLV---YFLIGKVY 747
I + S Y L+ K Y
Sbjct: 1081 IDHQNSQARGQYLLMMKYY 1099
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 10/152 (6%)
Query: 557 KDLTDMDKNSPE---AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
KD D +P+ A+ AGN + R+ A +F +A++ DP Y +
Sbjct: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522
Query: 614 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL- 672
++ ++A F N I P ++ YY +++ LAE KAL + P +++
Sbjct: 1523 LKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN 1582
Query: 673 ------CHIGVVQHALKKSEKALDTLNKAIVI 698
IG+++ A+ +ALD + A VI
Sbjct: 1583 FRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 4/128 (3%)
Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704
YY+ E L E + D + C G + L K + A++ L + I+++P
Sbjct: 897 YYESEVKILTE----EINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLN 952
Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 764
+HR + +K AL +L + + + Y ++Y+ LA++N++ A+
Sbjct: 953 AYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAI 1012
Query: 765 DLDPKGAN 772
P A+
Sbjct: 1013 KSTPTDAD 1020
Score = 39.3 bits (90), Expect = 0.015
Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 21/194 (10%)
Query: 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT 542
E IN + P+ Y C+ G Y +L + A V +E ++
Sbjct: 907 EEINDKTKYPAFAY------CRRGAIYRKLGKLQSAMNDLQRVILLE-------PLFLNA 953
Query: 543 LWHLQKDVALS-VLSKDLTDMD------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595
WH +++ L D++ KN+ EA+ + + +++ +AI + +AI+
Sbjct: 954 YWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIK 1013
Query: 596 VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655
P A Y G + +T ++ A+ F I +P+ +A G+ Y + E + A
Sbjct: 1014 STPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAI 1072
Query: 656 MHFQKALDINPQSS 669
F L+I+ Q+S
Sbjct: 1073 EDFTALLNIDHQNS 1086
>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
sapiens]
Length = 1614
Score = 82.0 bits (201), Expect = 2e-15
Identities = 52/194 (26%), Positives = 99/194 (51%), Gaps = 8/194 (4%)
Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633
GN F+ ++ + A+K A + N + +GH+ A+ +++AI +NP+
Sbjct: 1423 GNNFAAMQDINAAMKISTTA-EFLTNRGVIHEFMGHK-------QNAMKDYQDAITLNPK 1474
Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693
+ A++ G IY+ +FS A +F KAL +P++ +L + + LKK E+A +
Sbjct: 1475 YSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFA 1534
Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753
I P F+RA + ++Y+ A ++L + + P ++LVY KV K+G
Sbjct: 1535 NVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLI 1594
Query: 754 HLALMNFSWAMDLD 767
A+ +++ A+DL+
Sbjct: 1595 EEAMADYNQALDLE 1608
Score = 65.5 bits (158), Expect = 2e-10
Identities = 58/221 (26%), Positives = 93/221 (42%), Gaps = 4/221 (1%)
Query: 572 AAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH---EFVLTEELDKALACFRNAI 628
A C E + A+ FF A++++P + AY G+ E+ E +A F A+
Sbjct: 1309 ATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKAL 1368
Query: 629 RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688
+NP + A G Q KF A HF A+D +P++ + VV + + A
Sbjct: 1369 HINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAA 1428
Query: 689 LDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 748
+ +N A+ I F K ++A+++ ++ + PK SL YF G +Y
Sbjct: 1429 MQDINAAMKISTTAEFLTNRGVIHEFMGHK-QNAMKDYQDAITLNPKYSLAYFNAGNIYF 1487
Query: 749 KLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEE 789
Q A FS A+ DP+ + AI L EE
Sbjct: 1488 HHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEE 1528
Score = 59.7 bits (143), Expect = 1e-08
Identities = 71/315 (22%), Positives = 126/315 (40%), Gaps = 51/315 (16%)
Query: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556
N G + ++G+ F L ++ QA I R G ++T + H + + ++
Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALIS---------RTNGSLCHATAMCHHRINEFEEAVN 1325
Query: 557 KDLTDMDKNSP---EAWCAAGNCFSLQREHDIAIKF----FQRAIQVDPNYAYAYTLLGH 609
T K +P +A+ GN + ++ HD A K F +A+ ++P Y A G+
Sbjct: 1326 F-FTWALKINPCFLDAYVGRGNSY-MEYGHDEATKQAQKDFLKALHINPAYIKARISFGY 1383
Query: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGL---------------------------- 641
+ KA F AI +P++Y A+ G
Sbjct: 1384 NLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAE 1443
Query: 642 -----GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696
G+I+ A +Q A+ +NP+ S+ + G + ++ +A D +KA+
Sbjct: 1444 FLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKAL 1503
Query: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756
DP+N +RA +KY+ A ++ + + P + VYF Y L Q LA
Sbjct: 1504 KFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELA 1563
Query: 757 LMNFSWAMDLDPKGA 771
+ + A+ L P A
Sbjct: 1564 EEDLNKALSLKPNDA 1578
Score = 52.4 bits (124), Expect = 2e-06
Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 4/199 (2%)
Query: 552 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 611
+ +L++++ D K A+C G + + A+ QR I ++P + AY +
Sbjct: 902 VKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIY 961
Query: 612 VLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671
+ +++++AL + N + A+ IY ++ +LA +++ +A+ P + +
Sbjct: 962 LFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADI 1021
Query: 672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ 731
G + K A+D +K I DPK R NE + +A+++ L
Sbjct: 1022 YFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080
Query: 732 IVPKESLV---YFLIGKVY 747
I + S Y L+ K Y
Sbjct: 1081 IDHQNSQARGQYLLMMKYY 1099
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 10/152 (6%)
Query: 557 KDLTDMDKNSPE---AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
KD D +P+ A+ AGN + R+ A +F +A++ DP Y +
Sbjct: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522
Query: 614 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL- 672
++ ++A F N I P ++ YY +++ LAE KAL + P +++
Sbjct: 1523 LKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN 1582
Query: 673 ------CHIGVVQHALKKSEKALDTLNKAIVI 698
IG+++ A+ +ALD + A VI
Sbjct: 1583 FRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 4/128 (3%)
Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704
YY+ E L E + D + C G + L K + A++ L + I+++P
Sbjct: 897 YYESEVKILTE----EINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLN 952
Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 764
+HR + +K AL +L + + + Y ++Y+ LA++N++ A+
Sbjct: 953 AYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAI 1012
Query: 765 DLDPKGAN 772
P A+
Sbjct: 1013 KSTPTDAD 1020
Score = 39.3 bits (90), Expect = 0.015
Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 21/194 (10%)
Query: 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT 542
E IN + P+ Y C+ G Y +L + A V +E ++
Sbjct: 907 EEINDKTKYPAFAY------CRRGAIYRKLGKLQSAMNDLQRVILLE-------PLFLNA 953
Query: 543 LWHLQKDVALS-VLSKDLTDMD------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595
WH +++ L D++ KN+ EA+ + + +++ +AI + +AI+
Sbjct: 954 YWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIK 1013
Query: 596 VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655
P A Y G + +T ++ A+ F I +P+ +A G+ Y + E + A
Sbjct: 1014 STPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAI 1072
Query: 656 MHFQKALDINPQSS 669
F L+I+ Q+S
Sbjct: 1073 EDFTALLNIDHQNS 1086
>gi|118402578 anaphase-promoting complex, subunit 6 [Homo sapiens]
Length = 620
Score = 80.5 bits (197), Expect = 6e-15
Identities = 68/278 (24%), Positives = 122/278 (43%), Gaps = 14/278 (5%)
Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560
V+ + ++ ++ ++ S V + + + ++ TL L K L LS L
Sbjct: 233 VVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLV 292
Query: 561 DMDKNSPEAWCAAGNCFSLQREH--DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD 618
D+ ++P +W A G C+ L H + A ++ +A ++ Y A+ GH F + E D
Sbjct: 293 DLYPSNPVSWFAVG-CYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHD 351
Query: 619 KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVV 678
+A+A + A ++ + +G+ Y LAE F +AL I P+ ++ +GVV
Sbjct: 352 QAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVV 411
Query: 679 ---QHALKKSEK-ALDTLNK------AIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728
K +EK LD L K + +D PL + V +KY AL +
Sbjct: 412 AFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLN-NLGHVCRKLKKYAEALDYHRQ 470
Query: 729 LKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766
++P+ + Y IG ++ +G A+ F A+ L
Sbjct: 471 ALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL 508
>gi|118402580 anaphase-promoting complex, subunit 6 [Homo sapiens]
Length = 620
Score = 80.5 bits (197), Expect = 6e-15
Identities = 68/278 (24%), Positives = 122/278 (43%), Gaps = 14/278 (5%)
Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560
V+ + ++ ++ ++ S V + + + ++ TL L K L LS L
Sbjct: 233 VVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLV 292
Query: 561 DMDKNSPEAWCAAGNCFSLQREH--DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD 618
D+ ++P +W A G C+ L H + A ++ +A ++ Y A+ GH F + E D
Sbjct: 293 DLYPSNPVSWFAVG-CYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHD 351
Query: 619 KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVV 678
+A+A + A ++ + +G+ Y LAE F +AL I P+ ++ +GVV
Sbjct: 352 QAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVV 411
Query: 679 ---QHALKKSEK-ALDTLNK------AIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728
K +EK LD L K + +D PL + V +KY AL +
Sbjct: 412 AFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLN-NLGHVCRKLKKYAEALDYHRQ 470
Query: 729 LKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766
++P+ + Y IG ++ +G A+ F A+ L
Sbjct: 471 ALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL 508
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 77.0 bits (188), Expect = 7e-14
Identities = 53/222 (23%), Positives = 103/222 (46%), Gaps = 6/222 (2%)
Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624
N AW G F+ Q E +AI F++A+ +DPN+ AY LG+ D+A+A +
Sbjct: 179 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 238
Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 684
A+ ++P H L +YY+Q LA +++A+++ P C++
Sbjct: 239 LRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGS 298
Query: 685 SEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744
+A D N A+ + P + + A++ + A++ + ++ P+ + + +
Sbjct: 299 VAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLA 358
Query: 745 KVYKKLGQTHLALMNFSWAMDLDPKGAN------NQIKEAID 780
V ++ G+ ALM++ A+ + P A+ N +KE D
Sbjct: 359 SVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD 400
Score = 65.9 bits (159), Expect = 2e-10
Identities = 51/211 (24%), Positives = 96/211 (45%)
Query: 562 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL 621
+D N +A+ GN R D A+ + RA+ + PN+A + L + +D A+
Sbjct: 210 LDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAI 269
Query: 622 ACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHA 681
+R AI + P +A+ L ++ + AE + AL + P + L ++ ++
Sbjct: 270 DTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKRE 329
Query: 682 LKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYF 741
E+A+ KA+ + P+ + ASVL K + AL +E +I P + Y
Sbjct: 330 QGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYS 389
Query: 742 LIGKVYKKLGQTHLALMNFSWAMDLDPKGAN 772
+G K++ AL ++ A+ ++P A+
Sbjct: 390 NMGNTLKEMQDVQGALQCYTRAIQINPAFAD 420
Score = 60.8 bits (146), Expect = 5e-09
Identities = 44/201 (21%), Positives = 92/201 (45%)
Query: 568 EAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNA 627
EA+ GN + + + AI+ ++ A+++ P++ Y L V +++ A+ + +A
Sbjct: 80 EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 139
Query: 628 IRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687
++ NP Y LG + + A+ + KA++ P +V ++G V +A +
Sbjct: 140 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWL 199
Query: 688 ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVY 747
A+ KA+ +DP + +VL + A+ + P ++V+ + VY
Sbjct: 200 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 259
Query: 748 KKLGQTHLALMNFSWAMDLDP 768
+ G LA+ + A++L P
Sbjct: 260 YEQGLIDLAIDTYRRAIELQP 280
Score = 60.1 bits (144), Expect = 8e-09
Identities = 55/237 (23%), Positives = 100/237 (42%), Gaps = 7/237 (2%)
Query: 555 LSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLT 614
L D D N A AAG+ + A++ + A+Q +P+ + LG+
Sbjct: 108 LKPDFIDGYINLAAALVAAGDM-------EGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 160
Query: 615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCH 674
L++A AC+ AI P AW LG ++ Q + LA HF+KA+ ++P +
Sbjct: 161 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN 220
Query: 675 IGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVP 734
+G V + ++A+ +A+ + P + + + A V + A+ ++ P
Sbjct: 221 LGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP 280
Query: 735 KESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI 791
Y + K+ G A ++ A+ L P A++ A KR + EE +
Sbjct: 281 HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAV 337
Score = 59.3 bits (142), Expect = 1e-08
Identities = 45/185 (24%), Positives = 85/185 (45%)
Query: 584 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 643
D+AI ++RAI++ P++ AY L + + +A C+ A+R+ P H ++ L
Sbjct: 266 DLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLAN 325
Query: 644 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNP 703
I +Q A ++KAL++ P+ + ++ V K ++AL +AI I P
Sbjct: 326 IKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA 385
Query: 704 LCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWA 763
+ + L + + ALQ QI P + + + ++K G A+ ++ A
Sbjct: 386 DAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTA 445
Query: 764 MDLDP 768
+ L P
Sbjct: 446 LKLKP 450
Score = 50.4 bits (119), Expect = 7e-06
Identities = 46/191 (24%), Positives = 78/191 (40%)
Query: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640
R D + F AI+ +P A AY+ LG+ + +L +A+ +R+A+R+ P + +
Sbjct: 59 RRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYIN 118
Query: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700
L A + AL NP + +G + AL + E+A KAI P
Sbjct: 119 LAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQP 178
Query: 701 KNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNF 760
+ + V A + A+ E+ + P Y +G V K+ A+ +
Sbjct: 179 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 238
Query: 761 SWAMDLDPKGA 771
A+ L P A
Sbjct: 239 LRALSLSPNHA 249
Score = 47.0 bits (110), Expect = 7e-05
Identities = 49/216 (22%), Positives = 93/216 (43%), Gaps = 25/216 (11%)
Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRR 527
E G LA+ +Y + AI + H P + C + A E +AE ++ R
Sbjct: 261 EQGLIDLAIDTY--RRAIELQPHFPDAY-------CNLANALKEKGSVAEAEDCYNTALR 311
Query: 528 IENYRVEGMEIYSTTLWHLQKDV-----ALSVLSKDLTDMDKNSPEAWCAAGNCFS-LQR 581
+ + + L +++++ A+ + K L PE A N S LQ+
Sbjct: 312 LCPTHADSLN----NLANIKREQGNIEEAVRLYRKALEVF----PEFAAAHSNLASVLQQ 363
Query: 582 EHDI--AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWY 639
+ + A+ ++ AI++ P +A AY+ +G+ +++ AL C+ AI++NP +A
Sbjct: 364 QGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHS 423
Query: 640 GLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
L I+ A ++ AL + P C++
Sbjct: 424 NLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNL 459
Score = 40.4 bits (93), Expect = 0.007
Identities = 41/188 (21%), Positives = 76/188 (40%), Gaps = 6/188 (3%)
Query: 597 DPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM 656
+P+ LL LD++ AI+ NP A+ LG +Y ++ + A
Sbjct: 41 EPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIE 100
Query: 657 HFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFAN 716
H++ AL + P ++ A E A+ A+ +P + ++L A
Sbjct: 101 HYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 160
Query: 717 EKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK------G 770
+ + A + + P ++ + +G V+ G+ LA+ +F A+ LDP
Sbjct: 161 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN 220
Query: 771 ANNQIKEA 778
N +KEA
Sbjct: 221 LGNVLKEA 228
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 77.0 bits (188), Expect = 7e-14
Identities = 53/222 (23%), Positives = 103/222 (46%), Gaps = 6/222 (2%)
Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624
N AW G F+ Q E +AI F++A+ +DPN+ AY LG+ D+A+A +
Sbjct: 189 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 248
Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 684
A+ ++P H L +YY+Q LA +++A+++ P C++
Sbjct: 249 LRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGS 308
Query: 685 SEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744
+A D N A+ + P + + A++ + A++ + ++ P+ + + +
Sbjct: 309 VAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLA 368
Query: 745 KVYKKLGQTHLALMNFSWAMDLDPKGAN------NQIKEAID 780
V ++ G+ ALM++ A+ + P A+ N +KE D
Sbjct: 369 SVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD 410
Score = 65.9 bits (159), Expect = 2e-10
Identities = 51/211 (24%), Positives = 96/211 (45%)
Query: 562 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL 621
+D N +A+ GN R D A+ + RA+ + PN+A + L + +D A+
Sbjct: 220 LDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAI 279
Query: 622 ACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHA 681
+R AI + P +A+ L ++ + AE + AL + P + L ++ ++
Sbjct: 280 DTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKRE 339
Query: 682 LKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYF 741
E+A+ KA+ + P+ + ASVL K + AL +E +I P + Y
Sbjct: 340 QGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYS 399
Query: 742 LIGKVYKKLGQTHLALMNFSWAMDLDPKGAN 772
+G K++ AL ++ A+ ++P A+
Sbjct: 400 NMGNTLKEMQDVQGALQCYTRAIQINPAFAD 430
Score = 60.8 bits (146), Expect = 5e-09
Identities = 44/201 (21%), Positives = 92/201 (45%)
Query: 568 EAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNA 627
EA+ GN + + + AI+ ++ A+++ P++ Y L V +++ A+ + +A
Sbjct: 90 EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 149
Query: 628 IRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687
++ NP Y LG + + A+ + KA++ P +V ++G V +A +
Sbjct: 150 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWL 209
Query: 688 ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVY 747
A+ KA+ +DP + +VL + A+ + P ++V+ + VY
Sbjct: 210 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 269
Query: 748 KKLGQTHLALMNFSWAMDLDP 768
+ G LA+ + A++L P
Sbjct: 270 YEQGLIDLAIDTYRRAIELQP 290
Score = 60.1 bits (144), Expect = 8e-09
Identities = 55/237 (23%), Positives = 100/237 (42%), Gaps = 7/237 (2%)
Query: 555 LSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLT 614
L D D N A AAG+ + A++ + A+Q +P+ + LG+
Sbjct: 118 LKPDFIDGYINLAAALVAAGDM-------EGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 170
Query: 615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCH 674
L++A AC+ AI P AW LG ++ Q + LA HF+KA+ ++P +
Sbjct: 171 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN 230
Query: 675 IGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVP 734
+G V + ++A+ +A+ + P + + + A V + A+ ++ P
Sbjct: 231 LGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP 290
Query: 735 KESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI 791
Y + K+ G A ++ A+ L P A++ A KR + EE +
Sbjct: 291 HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAV 347
Score = 59.3 bits (142), Expect = 1e-08
Identities = 45/185 (24%), Positives = 85/185 (45%)
Query: 584 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 643
D+AI ++RAI++ P++ AY L + + +A C+ A+R+ P H ++ L
Sbjct: 276 DLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLAN 335
Query: 644 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNP 703
I +Q A ++KAL++ P+ + ++ V K ++AL +AI I P
Sbjct: 336 IKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA 395
Query: 704 LCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWA 763
+ + L + + ALQ QI P + + + ++K G A+ ++ A
Sbjct: 396 DAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTA 455
Query: 764 MDLDP 768
+ L P
Sbjct: 456 LKLKP 460
Score = 50.4 bits (119), Expect = 7e-06
Identities = 46/191 (24%), Positives = 78/191 (40%)
Query: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640
R D + F AI+ +P A AY+ LG+ + +L +A+ +R+A+R+ P + +
Sbjct: 69 RRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYIN 128
Query: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700
L A + AL NP + +G + AL + E+A KAI P
Sbjct: 129 LAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQP 188
Query: 701 KNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNF 760
+ + V A + A+ E+ + P Y +G V K+ A+ +
Sbjct: 189 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 248
Query: 761 SWAMDLDPKGA 771
A+ L P A
Sbjct: 249 LRALSLSPNHA 259
Score = 47.0 bits (110), Expect = 7e-05
Identities = 49/216 (22%), Positives = 93/216 (43%), Gaps = 25/216 (11%)
Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRR 527
E G LA+ +Y + AI + H P + C + A E +AE ++ R
Sbjct: 271 EQGLIDLAIDTY--RRAIELQPHFPDAY-------CNLANALKEKGSVAEAEDCYNTALR 321
Query: 528 IENYRVEGMEIYSTTLWHLQKDV-----ALSVLSKDLTDMDKNSPEAWCAAGNCFS-LQR 581
+ + + L +++++ A+ + K L PE A N S LQ+
Sbjct: 322 LCPTHADSLN----NLANIKREQGNIEEAVRLYRKALEVF----PEFAAAHSNLASVLQQ 373
Query: 582 EHDI--AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWY 639
+ + A+ ++ AI++ P +A AY+ +G+ +++ AL C+ AI++NP +A
Sbjct: 374 QGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHS 433
Query: 640 GLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
L I+ A ++ AL + P C++
Sbjct: 434 NLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNL 469
Score = 40.4 bits (93), Expect = 0.007
Identities = 41/188 (21%), Positives = 76/188 (40%), Gaps = 6/188 (3%)
Query: 597 DPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM 656
+P+ LL LD++ AI+ NP A+ LG +Y ++ + A
Sbjct: 51 EPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIE 110
Query: 657 HFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFAN 716
H++ AL + P ++ A E A+ A+ +P + ++L A
Sbjct: 111 HYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 170
Query: 717 EKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK------G 770
+ + A + + P ++ + +G V+ G+ LA+ +F A+ LDP
Sbjct: 171 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN 230
Query: 771 ANNQIKEA 778
N +KEA
Sbjct: 231 LGNVLKEA 238
>gi|212549736 anaphase-promoting complex subunit 7 isoform a [Homo
sapiens]
Length = 599
Score = 68.2 bits (165), Expect = 3e-11
Identities = 67/318 (21%), Positives = 129/318 (40%), Gaps = 8/318 (2%)
Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560
+L + YF + + F + + ++ Y ++GM++Y L + + L L
Sbjct: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332
Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620
++ E W +G + + A+ +AIQ++ N A L G + +A
Sbjct: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392
Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIGV 677
+ FR AIR+ P + + GL Y A + + K L N Q+ LL + +
Sbjct: 393 IIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCL 452
Query: 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKES 737
+ EKA L+KA+ P +A +L +KY+ + L +
Sbjct: 453 EDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRN-ALANQSDC 509
Query: 738 LVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQI 797
+++ ++G + + A+ +S A+ LDP + + E + K + TQEE +
Sbjct: 510 VLHRILGDFLVAVNEYQEAMDQYSIALSLDPN--DQKSLEGMQKMEKEESPTDATQEEDV 567
Query: 798 MGTDESQESSMTDADDTQ 815
+ S E + D++
Sbjct: 568 DDMEGSGEEGDLEGSDSE 585
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 62.8 bits (151), Expect = 1e-09
Identities = 54/209 (25%), Positives = 92/209 (44%), Gaps = 15/209 (7%)
Query: 567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRN 626
P A N +L R+ A ++QRA+Q+ P + A LG+ E+ ++A+ ++
Sbjct: 406 PRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKD 465
Query: 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSE 686
+I+ P +A+ L + +QE+F AE +Q + P SS L + GV E
Sbjct: 466 SIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPE 525
Query: 687 KALDTLNKAIVIDPKNPLCKFHRASVL-------FANEKYKSALQELEELKQIVPKESLV 739
KA+ +AI + P + + + + A E YK ALQ + + + P
Sbjct: 526 KAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSP----- 580
Query: 740 YFLIGKVYKKLGQTHLALMNFSWAMDLDP 768
+G +Y G+ AL + A L P
Sbjct: 581 ---LGALYYNTGRYEEALQIYQEAAALQP 606
Score = 60.1 bits (144), Expect = 8e-09
Identities = 39/175 (22%), Positives = 78/175 (44%), Gaps = 4/175 (2%)
Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560
+L +G Y+ Y +A +I+ E ++ + E + L + + ++ +
Sbjct: 577 ILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIV 636
Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLL----GHEFVLTEE 616
+ E + +S Q HD A+ +A+Q+ P + L G++
Sbjct: 637 SEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNL 696
Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671
LDKA +R A+++NP AW +G I + + K+ A ++++AL + P S +L
Sbjct: 697 LDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLL 751
Score = 58.5 bits (140), Expect = 2e-08
Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 10/227 (4%)
Query: 547 QKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL 606
+K+ A+++L KD +A+ + + + Q A + +Q I+ P+ + +
Sbjct: 455 KKEEAITLL-KDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNN 513
Query: 607 LGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666
G V T +KA+A ++ AI+++P H+ A LG +Y + S+AE +++AL +
Sbjct: 514 YGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAH 573
Query: 667 QSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQEL 726
++ + L +G + + + E+AL +A + P + A VL + K E
Sbjct: 574 KAEI-LSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTK----EA 628
Query: 727 EELKQIVPKESL----VYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769
E++ + E Y L+ +Y K AL A+ L PK
Sbjct: 629 EKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPK 675
Score = 44.3 bits (103), Expect = 5e-04
Identities = 47/244 (19%), Positives = 94/244 (38%), Gaps = 13/244 (5%)
Query: 492 PSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVA 551
PSHH + +GR Y L E AE + ++ ++ E + ++ +
Sbjct: 539 PSHHV----AMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGRYEE 593
Query: 552 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 611
+ ++ + + E A ++ + A K + + Y LL +
Sbjct: 594 ALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIY 653
Query: 612 VLTEELDKALACFRNAIRVNPRHYNA----WYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667
E DKAL A+++ P+ ++ G +Q A ++ A+ +NP
Sbjct: 654 SKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPD 713
Query: 668 SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELE 727
+ ++G +QH K A +A+ + P + L K + A + ++ + LQE+
Sbjct: 714 QAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKL----DRLEKRLQEVR 769
Query: 728 ELKQ 731
E Q
Sbjct: 770 EKDQ 773
Score = 38.9 bits (89), Expect = 0.020
Identities = 46/214 (21%), Positives = 89/214 (41%), Gaps = 12/214 (5%)
Query: 564 KNSPEAWCAAGNCFSLQR---EHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620
K SP A N L R E+ +A ++++RA+QV + A + LG + T ++A
Sbjct: 536 KLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQV-AHKAEILSPLGALYYNTGRYEEA 594
Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCH--IGVV 678
L ++ A + P L + + AE ++ ++ L C+ + +
Sbjct: 595 LQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHI--VSEETGCLECYRLLSAI 652
Query: 679 QHALKKSEKALDTLNKAIVIDPKNPL----CKFHRASVLFANEKYKSALQELEELKQIVP 734
+ +KALD ++KA+ + PK+P F + + L A + Q+ P
Sbjct: 653 YSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNP 712
Query: 735 KESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP 768
++ + +G + G+ A + A+ L P
Sbjct: 713 DQAQAWMNMGGIQHIKGKYVSARAYYERALQLVP 746
Score = 32.0 bits (71), Expect = 2.4
Identities = 23/117 (19%), Positives = 55/117 (47%), Gaps = 3/117 (2%)
Query: 624 FRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALK 683
FR+ ++ P + Y Q + A H++ AL + P+ + L ++G + +
Sbjct: 364 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TR 420
Query: 684 KSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVY 740
+ +A +A+ + P++ F+ ++L + EK + A+ L++ + P+ + Y
Sbjct: 421 DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAY 477
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 57.8 bits (138), Expect = 4e-08
Identities = 71/337 (21%), Positives = 140/337 (41%), Gaps = 41/337 (12%)
Query: 422 NINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYNC 481
NI +SLE+ + + ++PQ A NL++ A + +GK A+ YN
Sbjct: 82 NIQESLELFQT---------CAVLSPQ-SADNLKQVARSLFL-----LGKHKAAIEVYNE 126
Query: 482 KEAINILSHLPSHHYNTGWV-LCQIGRAYFELSEYMQAER------IFSEVRRIENYRVE 534
+N SH+ ++ L Q +A +L + R + ++ +E +
Sbjct: 127 AAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDK 186
Query: 535 GMEIYSTT---------------LWHLQKDV---ALSVLSKDLTDMDKNSPEAWCAAGNC 576
+E+Y L +LQ + A L LT D + +A AAG+
Sbjct: 187 AIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALT-YDPTNYKAILAAGSM 245
Query: 577 FSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYN 636
+ D+A+ ++ P + +G F ++ A++C + A + P +
Sbjct: 246 MQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWK 305
Query: 637 AWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696
Y LG+++ ++++ A A++ P+ L + V L+ E A +A+
Sbjct: 306 ILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAV 365
Query: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIV 733
+D NPL + A +L+ + K+AL + +E+++ V
Sbjct: 366 HLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKV 402
Score = 56.6 bits (135), Expect = 9e-08
Identities = 60/274 (21%), Positives = 109/274 (39%), Gaps = 17/274 (6%)
Query: 502 LCQIGRAYFELSEYMQAERIFSEVRRIE------NYRVEGMEIYSTTLWHLQKDV--ALS 553
L Q+ R+ F L ++ A +++E ++ ++ + IY Q + AL+
Sbjct: 104 LKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALN 163
Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
+ DLT + G L+ + D AI+ +++A++ P T LG ++
Sbjct: 164 LNRHDLT---------YIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQ 214
Query: 614 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLC 673
KA NA+ +P +Y A G + F +A ++ P+S L
Sbjct: 215 LGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWN 274
Query: 674 HIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIV 733
+IG+ KK A+ L +A + P + ++ V ++Y SA L
Sbjct: 275 NIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQ 334
Query: 734 PKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD 767
PK +Y L+ L A ++ A+ LD
Sbjct: 335 PKMGELYMLLAVALTNLEDIENAKRAYAEAVHLD 368
Score = 53.9 bits (128), Expect = 6e-07
Identities = 46/236 (19%), Positives = 99/236 (41%), Gaps = 1/236 (0%)
Query: 534 EGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRA 593
+ ++ + +L+ L K A + + +++ E G C+ ++ + A A
Sbjct: 102 DNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNA 161
Query: 594 IQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSL 653
+ ++ + Y +LG +L +LDKA+ ++ A+ +P + LG++Y + +
Sbjct: 162 LNLN-RHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQK 220
Query: 654 AEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVL 713
A H AL +P + + G + + AL P++P +
Sbjct: 221 AFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCF 280
Query: 714 FANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769
F +KY +A+ L+ + P + + + +G V+ + Q A S A++ PK
Sbjct: 281 FGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPK 336
>gi|118766328 transmembrane and tetratricopeptide repeat containing
4 isoform 2 [Homo sapiens]
Length = 741
Score = 57.8 bits (138), Expect = 4e-08
Identities = 38/153 (24%), Positives = 70/153 (45%)
Query: 588 KFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYK 647
+ F+ A+ V P A + +G A+ +R A+R+NP++ +A LG I +
Sbjct: 469 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 528
Query: 648 QEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKF 707
+ + AE A+ I P + ++G+VQ++LK+ E A + AI K P C +
Sbjct: 529 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYY 588
Query: 708 HRASVLFANEKYKSALQELEELKQIVPKESLVY 740
+ + ++ AL + P+ SL +
Sbjct: 589 NLGRLYADLNRHVDALNAWRNATVLKPEHSLAW 621
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/233 (19%), Positives = 95/233 (40%), Gaps = 34/233 (14%)
Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645
AI++++ A++++P Y +A LG+ EL +A A+++ P AW LG++
Sbjct: 501 AIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQ 560
Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705
++F AE ++ A+ + ++G + L + AL+ A V+ P++ L
Sbjct: 561 NSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLA 620
Query: 706 ----------------------------------KFHRASVLFANEKYKSALQELEELKQ 731
F A+VL ++KYK + + +
Sbjct: 621 WNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIK 680
Query: 732 IVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYL 784
P + + + +Y + G LA ++ ++ LDP + + + +R L
Sbjct: 681 ANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGLLRRKL 733
Score = 42.4 bits (98), Expect = 0.002
Identities = 50/255 (19%), Positives = 100/255 (39%), Gaps = 28/255 (10%)
Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFEL----SEYMQAERIFS 523
++ + L++C N K NI +L T + R Y E +Y+ A
Sbjct: 469 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAI-----RYYREAVRLNPKYVHAMNNLG 523
Query: 524 EVRRIENYRVEGMEIYSTTLWHLQKDVA-----LSVLSKDLTDMD-------------KN 565
+ + N E E+ S + +Q D A L ++ L + +
Sbjct: 524 NILKERNELQEAEELLSLAV-QIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRK 582
Query: 566 SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFR 625
P+ + G ++ H A+ ++ A + P ++ A+ + T L +A A R
Sbjct: 583 YPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGR 642
Query: 626 NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKS 685
A+ + P ++ + L + K +K+ +E F KA+ NP ++ ++ V+ H
Sbjct: 643 EALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHL 702
Query: 686 EKALDTLNKAIVIDP 700
+ A ++ +DP
Sbjct: 703 DLAKKHYEISLQLDP 717
Score = 36.6 bits (83), Expect = 0.097
Identities = 21/97 (21%), Positives = 50/97 (51%)
Query: 591 QRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEK 650
+ A+++ PN L + +++ ++ A F AI+ NP + L ++Y++
Sbjct: 642 REALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGH 701
Query: 651 FSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687
LA+ H++ +L ++P +S + G+++ L+ +K
Sbjct: 702 LDLAKKHYEISLQLDPTASGTKENYGLLRRKLELMQK 738
>gi|118766330 transmembrane and tetratricopeptide repeat containing
4 isoform 1 [Homo sapiens]
Length = 760
Score = 57.8 bits (138), Expect = 4e-08
Identities = 38/153 (24%), Positives = 70/153 (45%)
Query: 588 KFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYK 647
+ F+ A+ V P A + +G A+ +R A+R+NP++ +A LG I +
Sbjct: 488 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 547
Query: 648 QEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKF 707
+ + AE A+ I P + ++G+VQ++LK+ E A + AI K P C +
Sbjct: 548 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYY 607
Query: 708 HRASVLFANEKYKSALQELEELKQIVPKESLVY 740
+ + ++ AL + P+ SL +
Sbjct: 608 NLGRLYADLNRHVDALNAWRNATVLKPEHSLAW 640
Score = 57.0 bits (136), Expect = 7e-08
Identities = 46/233 (19%), Positives = 95/233 (40%), Gaps = 34/233 (14%)
Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645
AI++++ A++++P Y +A LG+ EL +A A+++ P AW LG++
Sbjct: 520 AIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQ 579
Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705
++F AE ++ A+ + ++G + L + AL+ A V+ P++ L
Sbjct: 580 NSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLA 639
Query: 706 ----------------------------------KFHRASVLFANEKYKSALQELEELKQ 731
F A+VL ++KYK + + +
Sbjct: 640 WNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIK 699
Query: 732 IVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYL 784
P + + + +Y + G LA ++ ++ LDP + + + +R L
Sbjct: 700 ANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGLLRRKL 752
Score = 42.4 bits (98), Expect = 0.002
Identities = 50/255 (19%), Positives = 100/255 (39%), Gaps = 28/255 (10%)
Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFEL----SEYMQAERIFS 523
++ + L++C N K NI +L T + R Y E +Y+ A
Sbjct: 488 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAI-----RYYREAVRLNPKYVHAMNNLG 542
Query: 524 EVRRIENYRVEGMEIYSTTLWHLQKDVA-----LSVLSKDLTDMD-------------KN 565
+ + N E E+ S + +Q D A L ++ L + +
Sbjct: 543 NILKERNELQEAEELLSLAV-QIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRK 601
Query: 566 SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFR 625
P+ + G ++ H A+ ++ A + P ++ A+ + T L +A A R
Sbjct: 602 YPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGR 661
Query: 626 NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKS 685
A+ + P ++ + L + K +K+ +E F KA+ NP ++ ++ V+ H
Sbjct: 662 EALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHL 721
Query: 686 EKALDTLNKAIVIDP 700
+ A ++ +DP
Sbjct: 722 DLAKKHYEISLQLDP 736
Score = 36.6 bits (83), Expect = 0.097
Identities = 21/97 (21%), Positives = 50/97 (51%)
Query: 591 QRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEK 650
+ A+++ PN L + +++ ++ A F AI+ NP + L ++Y++
Sbjct: 661 REALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGH 720
Query: 651 FSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687
LA+ H++ +L ++P +S + G+++ L+ +K
Sbjct: 721 LDLAKKHYEISLQLDPTASGTKENYGLLRRKLELMQK 757
>gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo
sapiens]
Length = 639
Score = 55.5 bits (132), Expect = 2e-07
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%)
Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597
+ S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V
Sbjct: 462 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 518
Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657
PN + LG + ++A+A +R A+ + P + + Y LG+ A H
Sbjct: 519 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 578
Query: 658 FQKALDINPQS 668
F +AL++ +S
Sbjct: 579 FLEALNMQRKS 589
Score = 35.8 bits (81), Expect = 0.17
Identities = 20/77 (25%), Positives = 36/77 (46%)
Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
+L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L +
Sbjct: 350 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 409
Query: 676 GVVQHALKKSEKALDTL 692
V +A +TL
Sbjct: 410 AVSFTNESLQRQACETL 426
Score = 30.4 bits (67), Expect = 7.0
Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%)
Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
+L + D EAW G + + +AI +R +++ P+ A L F
Sbjct: 356 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 415
Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657
+A R+ +R P + + A G LG + + E+
Sbjct: 416 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 474
Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715
F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L
Sbjct: 475 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 534
Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770
+ + A+ ++ P + +G LG A+ +F A+++ P+G
Sbjct: 535 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 594
Query: 771 ANNQIKEAI 779
+ E I
Sbjct: 595 EGGAMSENI 603
>gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo
sapiens]
Length = 639
Score = 55.5 bits (132), Expect = 2e-07
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%)
Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597
+ S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V
Sbjct: 462 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 518
Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657
PN + LG + ++A+A +R A+ + P + + Y LG+ A H
Sbjct: 519 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 578
Query: 658 FQKALDINPQS 668
F +AL++ +S
Sbjct: 579 FLEALNMQRKS 589
Score = 35.8 bits (81), Expect = 0.17
Identities = 20/77 (25%), Positives = 36/77 (46%)
Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
+L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L +
Sbjct: 350 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 409
Query: 676 GVVQHALKKSEKALDTL 692
V +A +TL
Sbjct: 410 AVSFTNESLQRQACETL 426
Score = 30.4 bits (67), Expect = 7.0
Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%)
Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
+L + D EAW G + + +AI +R +++ P+ A L F
Sbjct: 356 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 415
Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657
+A R+ +R P + + A G LG + + E+
Sbjct: 416 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 474
Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715
F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L
Sbjct: 475 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 534
Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770
+ + A+ ++ P + +G LG A+ +F A+++ P+G
Sbjct: 535 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 594
Query: 771 ANNQIKEAI 779
+ E I
Sbjct: 595 EGGAMSENI 603
>gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo
sapiens]
Length = 602
Score = 55.5 bits (132), Expect = 2e-07
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%)
Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597
+ S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V
Sbjct: 425 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 481
Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657
PN + LG + ++A+A +R A+ + P + + Y LG+ A H
Sbjct: 482 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 541
Query: 658 FQKALDINPQS 668
F +AL++ +S
Sbjct: 542 FLEALNMQRKS 552
Score = 35.8 bits (81), Expect = 0.17
Identities = 20/77 (25%), Positives = 36/77 (46%)
Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
+L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L +
Sbjct: 313 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 372
Query: 676 GVVQHALKKSEKALDTL 692
V +A +TL
Sbjct: 373 AVSFTNESLQRQACETL 389
Score = 30.4 bits (67), Expect = 7.0
Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%)
Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
+L + D EAW G + + +AI +R +++ P+ A L F
Sbjct: 319 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 378
Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657
+A R+ +R P + + A G LG + + E+
Sbjct: 379 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 437
Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715
F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L
Sbjct: 438 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 497
Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770
+ + A+ ++ P + +G LG A+ +F A+++ P+G
Sbjct: 498 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 557
Query: 771 ANNQIKEAI 779
+ E I
Sbjct: 558 EGGAMSENI 566
>gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo
sapiens]
Length = 654
Score = 55.5 bits (132), Expect = 2e-07
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%)
Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597
+ S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V
Sbjct: 477 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 533
Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657
PN + LG + ++A+A +R A+ + P + + Y LG+ A H
Sbjct: 534 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 593
Query: 658 FQKALDINPQS 668
F +AL++ +S
Sbjct: 594 FLEALNMQRKS 604
Score = 35.8 bits (81), Expect = 0.17
Identities = 20/77 (25%), Positives = 36/77 (46%)
Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
+L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L +
Sbjct: 365 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 424
Query: 676 GVVQHALKKSEKALDTL 692
V +A +TL
Sbjct: 425 AVSFTNESLQRQACETL 441
Score = 30.4 bits (67), Expect = 7.0
Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%)
Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
+L + D EAW G + + +AI +R +++ P+ A L F
Sbjct: 371 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 430
Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657
+A R+ +R P + + A G LG + + E+
Sbjct: 431 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 489
Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715
F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L
Sbjct: 490 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 549
Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770
+ + A+ ++ P + +G LG A+ +F A+++ P+G
Sbjct: 550 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 609
Query: 771 ANNQIKEAI 779
+ E I
Sbjct: 610 EGGAMSENI 618
>gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo
sapiens]
Length = 631
Score = 55.5 bits (132), Expect = 2e-07
Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%)
Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597
+ S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V
Sbjct: 454 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 510
Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657
PN + LG + ++A+A +R A+ + P + + Y LG+ A H
Sbjct: 511 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 570
Query: 658 FQKALDINPQS 668
F +AL++ +S
Sbjct: 571 FLEALNMQRKS 581
Score = 35.8 bits (81), Expect = 0.17
Identities = 20/77 (25%), Positives = 36/77 (46%)
Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
+L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L +
Sbjct: 342 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 401
Query: 676 GVVQHALKKSEKALDTL 692
V +A +TL
Sbjct: 402 AVSFTNESLQRQACETL 418
Score = 30.4 bits (67), Expect = 7.0
Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%)
Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613
+L + D EAW G + + +AI +R +++ P+ A L F
Sbjct: 348 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 407
Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657
+A R+ +R P + + A G LG + + E+
Sbjct: 408 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 466
Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715
F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L
Sbjct: 467 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 526
Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770
+ + A+ ++ P + +G LG A+ +F A+++ P+G
Sbjct: 527 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 586
Query: 771 ANNQIKEAI 779
+ E I
Sbjct: 587 EGGAMSENI 595
>gi|224809432 transmembrane and tetratricopeptide repeat containing
3 [Homo sapiens]
Length = 914
Score = 55.5 bits (132), Expect = 2e-07
Identities = 41/156 (26%), Positives = 77/156 (49%), Gaps = 4/156 (2%)
Query: 593 AIQVDPNYAYAYTLLGHEFVLTEE-LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKF 651
A ++ PN+ Y L + E L++A +R AI + P A+ G + K K
Sbjct: 520 AARIAPNHLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKP 579
Query: 652 SLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRAS 711
A+ + KAL+++ ++ L ++ +V LK+ +AL N+A+ ++PK+ L F+ A
Sbjct: 580 LKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAI 639
Query: 712 VLFANEKYKSALQELEELKQIVPKESL---VYFLIG 744
V+ + + K + + L + +E L YF +G
Sbjct: 640 VMQESGEVKLRPEARKRLLSYINEEPLDANGYFNLG 675
Score = 53.9 bits (128), Expect = 6e-07
Identities = 57/275 (20%), Positives = 115/275 (41%), Gaps = 28/275 (10%)
Query: 544 WHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYA 603
W + + +S L ++KN+ + W G+ ++ + A+K+F +A V P+ A
Sbjct: 428 WESEYTLFMSALK-----VNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGA 482
Query: 604 YTLLGHEFV---LTEELDKALACFRN-----------AIRVNPRHYNAWYGL-GMIYYKQ 648
+ +G + T+E +++ ++ A R+ P H N + L +I +
Sbjct: 483 HMNVGRTYKNLNRTKEAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYINLANLIRANE 542
Query: 649 EKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFH 708
+ A+ +++A+ + P G + + K KA + KA+ +D N ++
Sbjct: 543 SRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYN 602
Query: 709 RASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHL------ALMNFSW 762
A V ++ AL+ ++ PK L F V ++ G+ L L+++
Sbjct: 603 LAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYIN 662
Query: 763 AMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQI 797
LD G N A+D + D+E I ++ I
Sbjct: 663 EEPLDANGYFNLGMLAMDDK--KDNEAEIWMKKAI 695
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/141 (22%), Positives = 64/141 (45%), Gaps = 7/141 (4%)
Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD-- 618
++D+N+ + W +E + A+K F RA++++P + A L V+ E +
Sbjct: 591 ELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLA--LFNSAIVMQESGEVK 648
Query: 619 ---KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675
+A + I P N ++ LGM+ +K + AE+ +KA+ + L ++
Sbjct: 649 LRPEARKRLLSYINEEPLDANGYFNLGMLAMDDKKDNEAEIWMKKAIKLQADFRSALFNL 708
Query: 676 GVVQHALKKSEKALDTLNKAI 696
++ K KAL L + +
Sbjct: 709 ALLYSQTAKELKALPILEELL 729
Score = 40.4 bits (93), Expect = 0.007
Identities = 44/227 (19%), Positives = 86/227 (37%), Gaps = 38/227 (16%)
Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645
A + +++AI + P++ AY G + + KA + A+ ++ + + WY L +++
Sbjct: 548 ADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVH 607
Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHAL----------------------- 682
+ ++ + A +F +AL++NP+ + L + +V
Sbjct: 608 IELKEPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYINEEPLD 667
Query: 683 --------------KKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728
KK +A + KAI + F+ A + K AL LEE
Sbjct: 668 ANGYFNLGMLAMDDKKDNEAEIWMKKAIKLQADFRSALFNLALLYSQTAKELKALPILEE 727
Query: 729 LKQIVPKESLVYFLIGKVYKKLGQTHL-ALMNFSWAMDLDPKGANNQ 774
L + P L G + + L A F +++DP +
Sbjct: 728 LLRYYPDHIKGLILKGDILMNQKKDILGAKKCFERILEMDPSNVQGK 774
Score = 32.3 bits (72), Expect = 1.8
Identities = 18/102 (17%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD--KALACFRNAIRVNPRHYNAWYGLGM 643
A+ + ++ P++ L G + ++ ++ D A CF + ++P + + L +
Sbjct: 721 ALPILEELLRYYPDHIKGLILKG-DILMNQKKDILGAKKCFERILEMDPSNVQGKHNLCV 779
Query: 644 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKS 685
+Y++++ AE + L + P + H+ +V+ + S
Sbjct: 780 VYFEEKDLLKAERCLLETLALAPHEEYIQRHLNIVRDKISSS 821
>gi|212549738 anaphase-promoting complex subunit 7 isoform b [Homo
sapiens]
Length = 537
Score = 55.1 bits (131), Expect = 3e-07
Identities = 50/226 (22%), Positives = 92/226 (40%), Gaps = 5/226 (2%)
Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560
+L + YF + + F + + ++ Y ++GM++Y L + + L L
Sbjct: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332
Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620
++ E W +G + + A+ +AIQ++ N A L G + +A
Sbjct: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392
Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIGV 677
+ FR AIR+ P + + GL Y A + + K L N Q+ LL + +
Sbjct: 393 IIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCL 452
Query: 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSAL 723
+ EKA L+KA+ P +A +L +KY+ +
Sbjct: 453 EDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 496
>gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo
sapiens]
Length = 860
Score = 54.3 bits (129), Expect = 5e-07
Identities = 57/251 (22%), Positives = 104/251 (41%), Gaps = 18/251 (7%)
Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFE--LSEYMQAERIFSEV 525
E+ Y+ + S EAI S + + + G AY + L + AE E+
Sbjct: 146 ELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFEL 205
Query: 526 RRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEA--WCAAGNCFSLQREH 583
R+ + E++ L ++ DLT + P A + G + + ++
Sbjct: 206 SRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDY 265
Query: 584 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 643
A + FQ++++++ N A G F L +A+ F+ A++ +A+ LG
Sbjct: 266 ATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQ 325
Query: 644 IYYKQEKFSLAEMHFQKALDINPQ-------SSVLLCHIGVVQHALKKSEKALDTLNKAI 696
Y + F A FQKAL +N ++L H G +Q ALK ++ L
Sbjct: 326 AYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQ------ 379
Query: 697 VIDPKNPLCKF 707
++P N +C++
Sbjct: 380 -LEPYNEVCQY 389
Score = 45.8 bits (107), Expect = 2e-04
Identities = 47/236 (19%), Positives = 99/236 (41%), Gaps = 2/236 (0%)
Query: 549 DVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG 608
++AL LS+ +T ++ + PE + S + A+ +AIQ+ P+ A Y G
Sbjct: 199 ELALFELSRVIT-LEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRG 256
Query: 609 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 668
+ ++E+ A F+ ++ +N A G+ ++ + A F++AL
Sbjct: 257 TLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDF 316
Query: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728
+G L E A ++ KA++++ + R +L+ + + AL+ +
Sbjct: 317 IDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKR 376
Query: 729 LKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYL 784
Q+ P + ++ G + +GQ + + + M DP E + +YL
Sbjct: 377 CLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKYL 432
>gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo
sapiens]
Length = 807
Score = 53.5 bits (127), Expect = 8e-07
Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 16/183 (8%)
Query: 534 EGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEA--WCAAGNCFSLQREHDIAIKFFQ 591
E + +ST L L ++ DLT + P A + G + + ++ A + FQ
Sbjct: 161 EAIRHFSTMLQILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQ 220
Query: 592 RAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKF 651
++++++ N A G F L +A+ F+ A++ +A+ LG Y + F
Sbjct: 221 QSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNF 280
Query: 652 SLAEMHFQKALDINPQ-------SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704
A FQKAL +N ++L H G +Q ALK ++ L ++P N +
Sbjct: 281 EAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQ-------LEPYNEV 333
Query: 705 CKF 707
C++
Sbjct: 334 CQY 336
Score = 42.0 bits (97), Expect = 0.002
Identities = 39/199 (19%), Positives = 82/199 (41%), Gaps = 1/199 (0%)
Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645
A+ +AIQ+ P+ A Y G + ++E+ A F+ ++ +N A G+ +
Sbjct: 182 AVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTF 240
Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705
+ + A F++AL +G L E A ++ KA++++ +
Sbjct: 241 FHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQT 300
Query: 706 KFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMD 765
R +L+ + + AL+ + Q+ P + ++ G + +GQ + + + M
Sbjct: 301 LQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVML 360
Query: 766 LDPKGANNQIKEAIDKRYL 784
DP E + +YL
Sbjct: 361 NDPLPGQKASPEYLKVKYL 379
>gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo
sapiens]
Length = 515
Score = 52.0 bits (123), Expect = 2e-06
Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGME-IYSTTLWHLQKDVALSVLSKDL 559
+LC I R Y E++ A + EV + +N VE + I S + Q ++AL + L
Sbjct: 294 LLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRR-L 352
Query: 560 TDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL---LGHEFVLTEE 616
M + + + G C +++D+ + F+RA+ + N A + LGH V +
Sbjct: 353 LQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGD 412
Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666
+ A CFR A+ N H A+ L ++ ++ A Q A + P
Sbjct: 413 TNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 462
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/184 (17%), Positives = 74/184 (40%), Gaps = 2/184 (1%)
Query: 482 KEAINILSHLPSH-HYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540
K A+++ + H Y W QIG+ Y+ L Y +AE+ F + + V+ +
Sbjct: 207 KTALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLA 265
Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600
L + V L K D C + A ++++ ++ D +
Sbjct: 266 KVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTH 325
Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660
A +G +++ + AL +R +++ + + LG+ + +++ + F++
Sbjct: 326 VEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFER 385
Query: 661 ALDI 664
AL +
Sbjct: 386 ALSL 389
>gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo
sapiens]
Length = 475
Score = 52.0 bits (123), Expect = 2e-06
Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGME-IYSTTLWHLQKDVALSVLSKDL 559
+LC I R Y E++ A + EV + +N VE + I S + Q ++AL + L
Sbjct: 254 LLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRR-L 312
Query: 560 TDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL---LGHEFVLTEE 616
M + + + G C +++D+ + F+RA+ + N A + LGH V +
Sbjct: 313 LQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGD 372
Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666
+ A CFR A+ N H A+ L ++ ++ A Q A + P
Sbjct: 373 TNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 422
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/184 (17%), Positives = 74/184 (40%), Gaps = 2/184 (1%)
Query: 482 KEAINILSHLPSH-HYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540
K A+++ + H Y W QIG+ Y+ L Y +AE+ F + + V+ +
Sbjct: 167 KTALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLA 225
Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600
L + V L K D C + A ++++ ++ D +
Sbjct: 226 KVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTH 285
Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660
A +G +++ + AL +R +++ + + LG+ + +++ + F++
Sbjct: 286 VEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFER 345
Query: 661 ALDI 664
AL +
Sbjct: 346 ALSL 349
>gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo
sapiens]
Length = 505
Score = 52.0 bits (123), Expect = 2e-06
Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 5/170 (2%)
Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGME-IYSTTLWHLQKDVALSVLSKDL 559
+LC I R Y E++ A + EV + +N VE + I S + Q ++AL + L
Sbjct: 284 LLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRR-L 342
Query: 560 TDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL---LGHEFVLTEE 616
M + + + G C +++D+ + F+RA+ + N A + LGH V +
Sbjct: 343 LQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGD 402
Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666
+ A CFR A+ N H A+ L ++ ++ A Q A + P
Sbjct: 403 TNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 452
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/184 (17%), Positives = 74/184 (40%), Gaps = 2/184 (1%)
Query: 482 KEAINILSHLPSH-HYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540
K A+++ + H Y W QIG+ Y+ L Y +AE+ F + + V+ +
Sbjct: 197 KTALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLA 255
Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600
L + V L K D C + A ++++ ++ D +
Sbjct: 256 KVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTH 315
Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660
A +G +++ + AL +R +++ + + LG+ + +++ + F++
Sbjct: 316 VEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFER 375
Query: 661 ALDI 664
AL +
Sbjct: 376 ALSL 379
>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
A [Homo sapiens]
Length = 608
Score = 52.0 bits (123), Expect = 2e-06
Identities = 56/254 (22%), Positives = 113/254 (44%), Gaps = 27/254 (10%)
Query: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640
+E D K+ A+ + + Y L+G+ +LDK ++ +++ NA
Sbjct: 319 KEIDAEGKYMAEALLLRATF---YLLIGNANAAKPDLDKVISLKEANVKLRA---NALIK 372
Query: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700
G +Y +Q++ L+ F A DI+PQ++ + H G ++ L + E+A+ ++ I + P
Sbjct: 373 RGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRP 432
Query: 701 KNPLCKFHRASVLFA-------NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753
++ L + + L+ + + ++A++ EE+ + P+ + Y L + Q
Sbjct: 433 ESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQF 492
Query: 754 HLALMNFSWAMDLDPKGANNQIKEAI----DKRYLPDDEEPITQEEQI----------MG 799
A + +DL+P A + + + K+ L E I++ +I MG
Sbjct: 493 GKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMG 552
Query: 800 TDESQESSMTDADD 813
T E Q +M A D
Sbjct: 553 TIEVQRGNMEKAID 566
Score = 40.0 bits (92), Expect = 0.009
Identities = 39/165 (23%), Positives = 67/165 (40%), Gaps = 16/165 (9%)
Query: 547 QKDVALSVLSKDLTDMDK----NSPEAWCAAGNCFSLQREH---------DIAIKFFQRA 593
Q + L + + + D D+ A A CF+L R+ A+K F+
Sbjct: 409 QLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEV 468
Query: 594 IQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWY--GLGMIYYKQEKF 651
I+ P A Y L ++ KA + I + P + + GL + +KQ+
Sbjct: 469 IKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLD 528
Query: 652 SLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696
E+ KA++I+ + +G ++ EKA+D NKAI
Sbjct: 529 RGLEL-ISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAI 572
Score = 32.3 bits (72), Expect = 1.8
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 3/120 (2%)
Query: 513 SEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCA 572
S+ A + F EV + EG +Y+ L Q+ + D++ ++ +
Sbjct: 456 SQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVH 515
Query: 573 AGNCFSLQREHDI--AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV 630
G LQ + D+ ++ +AI++D +AY +G V ++KA+ F AI +
Sbjct: 516 KG-LLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINL 574
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,917,031
Number of Sequences: 37866
Number of extensions: 1521477
Number of successful extensions: 7049
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 88
Number of HSP's successfully gapped in prelim test: 198
Number of HSP's that attempted gapping in prelim test: 5691
Number of HSP's gapped (non-prelim): 1048
length of query: 824
length of database: 18,247,518
effective HSP length: 111
effective length of query: 713
effective length of database: 14,044,392
effective search space: 10013651496
effective search space used: 10013651496
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.