BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapiens] (824 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 1658 0.0 gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 1652 0.0 gi|239758107 PREDICTED: similar to Cell division cycle 27 homolo... 130 5e-30 gi|239750229 PREDICTED: similar to Cell division cycle 27 homolo... 130 5e-30 gi|118402596 cell division cycle protein 23 [Homo sapiens] 123 6e-28 gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 82 2e-15 gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ... 82 2e-15 gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom... 82 2e-15 gi|118402578 anaphase-promoting complex, subunit 6 [Homo sapiens] 80 6e-15 gi|118402580 anaphase-promoting complex, subunit 6 [Homo sapiens] 80 6e-15 gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 77 7e-14 gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 77 7e-14 gi|212549736 anaphase-promoting complex subunit 7 isoform a [Hom... 68 3e-11 gi|83415184 transmembrane and tetratricopeptide repeat containin... 63 1e-09 gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 58 4e-08 gi|118766328 transmembrane and tetratricopeptide repeat containi... 58 4e-08 gi|118766330 transmembrane and tetratricopeptide repeat containi... 58 4e-08 gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sap... 55 2e-07 gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sap... 55 2e-07 gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sap... 55 2e-07 gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sap... 55 2e-07 gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapi... 55 2e-07 gi|224809432 transmembrane and tetratricopeptide repeat containi... 55 2e-07 gi|212549738 anaphase-promoting complex subunit 7 isoform b [Hom... 55 3e-07 gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo ... 54 5e-07 gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo ... 54 8e-07 gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo sa... 52 2e-06 gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo sa... 52 2e-06 gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo sa... 52 2e-06 gi|54607135 translocase of outer mitochondrial membrane 70 homol... 52 2e-06 >gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapiens] Length = 824 Score = 1658 bits (4294), Expect = 0.0 Identities = 824/824 (100%), Positives = 824/824 (100%) Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL Sbjct: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 Query: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL Sbjct: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120 Query: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL Sbjct: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180 Query: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI Sbjct: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240 Query: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN Sbjct: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300 Query: 301 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP 360 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP Sbjct: 301 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP 360 Query: 361 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ 420 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ Sbjct: 361 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ 420 Query: 421 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN 480 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN Sbjct: 421 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN 480 Query: 481 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS Sbjct: 481 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY Sbjct: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK Sbjct: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 Query: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK Sbjct: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 Query: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID Sbjct: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 Query: 781 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF Sbjct: 781 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824 >gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapiens] Length = 830 Score = 1652 bits (4277), Expect = 0.0 Identities = 824/830 (99%), Positives = 824/830 (99%), Gaps = 6/830 (0%) Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL Sbjct: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 Query: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL Sbjct: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120 Query: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL Sbjct: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180 Query: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI Sbjct: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240 Query: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN Sbjct: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300 Query: 301 YTNTPPVIDVPSTGAPSKK------SVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGP 354 YTNTPPVIDVPSTGAPSKK SVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGP Sbjct: 301 YTNTPPVIDVPSTGAPSKKTFRVLQSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGP 360 Query: 355 QTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTN 414 QTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTN Sbjct: 361 QTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTN 420 Query: 415 KGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYL 474 KGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYL Sbjct: 421 KGGITQPNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYL 480 Query: 475 ALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVE 534 ALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVE Sbjct: 481 ALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVE 540 Query: 535 GMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAI 594 GMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAI Sbjct: 541 GMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAI 600 Query: 595 QVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLA 654 QVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLA Sbjct: 601 QVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLA 660 Query: 655 EMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLF 714 EMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLF Sbjct: 661 EMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLF 720 Query: 715 ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQ 774 ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQ Sbjct: 721 ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQ 780 Query: 775 IKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824 IKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF Sbjct: 781 IKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 830 >gi|239758107 PREDICTED: similar to Cell division cycle 27 homolog (S. cerevisiae) [Homo sapiens] Length = 70 Score = 130 bits (327), Expect = 5e-30 Identities = 62/70 (88%), Positives = 64/70 (91%) Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 M VLQEPVQAAIWQALNHYAYRD VFLAE L+AEVHSEEA+FLLATC YR GKAYKAYRL Sbjct: 1 MMVLQEPVQAAIWQALNHYAYRDGVFLAEHLHAEVHSEEAMFLLATCSYRPGKAYKAYRL 60 Query: 61 LKGHSCTTPQ 70 LKGHSC TPQ Sbjct: 61 LKGHSCPTPQ 70 >gi|239750229 PREDICTED: similar to Cell division cycle 27 homolog (S. cerevisiae) [Homo sapiens] Length = 70 Score = 130 bits (327), Expect = 5e-30 Identities = 62/70 (88%), Positives = 64/70 (91%) Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 M VLQEPVQAAIWQALNHYAYRD VFLAE L+AEVHSEEA+FLLATC YR GKAYKAYRL Sbjct: 1 MMVLQEPVQAAIWQALNHYAYRDGVFLAEHLHAEVHSEEAMFLLATCSYRPGKAYKAYRL 60 Query: 61 LKGHSCTTPQ 70 LKGHSC TPQ Sbjct: 61 LKGHSCPTPQ 70 >gi|118402596 cell division cycle protein 23 [Homo sapiens] Length = 597 Score = 123 bits (309), Expect = 6e-28 Identities = 63/191 (32%), Positives = 109/191 (57%) Query: 498 TGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSK 557 + +++ QI AY + + +A IF+E+R+ + YR+E M+ +S L+ LS L+ Sbjct: 262 SSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAH 321 Query: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEEL 617 +L ++DK E C GN +SL+ +H+ A +FQRA++++P Y A+TL+GHE++ + Sbjct: 322 NLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNT 381 Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 A+ +R+AI VN R Y AWYGLG Y + ++++A + P S +L +G Sbjct: 382 SAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGE 441 Query: 678 VQHALKKSEKA 688 L + +A Sbjct: 442 CYEKLNQLVEA 452 Score = 38.5 bits (88), Expect = 0.026 Identities = 66/292 (22%), Positives = 107/292 (36%), Gaps = 44/292 (15%) Query: 505 IGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDK 564 + +AYF++ EY +A + Y + +YS L +K KD +D Sbjct: 89 LAKAYFDVKEYDRAAHFLHGCNSKKAYF---LYMYSRYLSGEKK--------KDDETVDS 137 Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 P N RE + + +A ++D Y Y ++ + L +E A+ F Sbjct: 138 LGPLEKGQVKN--EALRELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKE---AIDVF 192 Query: 625 RNAIRVNPRHYNAW-------------------------YGLGMIYYKQEKFSLAEMHFQ 659 A V P H+ AW + L IY + + A +Q Sbjct: 193 VEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQ 252 Query: 660 KALDIN-PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEK 718 +D+ +SS ++ I V H ++ +KAL N+ DP + S L Sbjct: 253 NLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYR-IENMDTFSNLLYVRS 311 Query: 719 YKSALQEL-EELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769 KS L L L +I +IG Y Q A + F A+ L+P+ Sbjct: 312 MKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPR 363 Score = 35.4 bits (80), Expect = 0.22 Identities = 33/177 (18%), Positives = 66/177 (37%), Gaps = 16/177 (9%) Query: 503 CQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDM 562 C IG Y S++ +A F ++ + + ++ A + ++ Sbjct: 335 CVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV 394 Query: 563 DKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALA 622 +K AW G + + + + +++RA Q+ PN + LG + +L +A Sbjct: 395 NKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKK 454 Query: 623 CFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQ 679 C+ A Y +G + K LA++H Q + C+I +Q Sbjct: 455 CYWRA-----------YAVGDV-EKMALVKLAKLHEQ----LTESEQAAQCYIKYIQ 495 >gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo sapiens] Length = 1614 Score = 82.0 bits (201), Expect = 2e-15 Identities = 52/194 (26%), Positives = 99/194 (51%), Gaps = 8/194 (4%) Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633 GN F+ ++ + A+K A + N + +GH+ A+ +++AI +NP+ Sbjct: 1423 GNNFAAMQDINAAMKISTTA-EFLTNRGVIHEFMGHK-------QNAMKDYQDAITLNPK 1474 Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 + A++ G IY+ +FS A +F KAL +P++ +L + + LKK E+A + Sbjct: 1475 YSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFA 1534 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753 I P F+RA + ++Y+ A ++L + + P ++LVY KV K+G Sbjct: 1535 NVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLI 1594 Query: 754 HLALMNFSWAMDLD 767 A+ +++ A+DL+ Sbjct: 1595 EEAMADYNQALDLE 1608 Score = 65.5 bits (158), Expect = 2e-10 Identities = 58/221 (26%), Positives = 93/221 (42%), Gaps = 4/221 (1%) Query: 572 AAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH---EFVLTEELDKALACFRNAI 628 A C E + A+ FF A++++P + AY G+ E+ E +A F A+ Sbjct: 1309 ATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKAL 1368 Query: 629 RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688 +NP + A G Q KF A HF A+D +P++ + VV + + A Sbjct: 1369 HINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAA 1428 Query: 689 LDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 748 + +N A+ I F K ++A+++ ++ + PK SL YF G +Y Sbjct: 1429 MQDINAAMKISTTAEFLTNRGVIHEFMGHK-QNAMKDYQDAITLNPKYSLAYFNAGNIYF 1487 Query: 749 KLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEE 789 Q A FS A+ DP+ + AI L EE Sbjct: 1488 HHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEE 1528 Score = 59.7 bits (143), Expect = 1e-08 Identities = 71/315 (22%), Positives = 126/315 (40%), Gaps = 51/315 (16%) Query: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556 N G + ++G+ F L ++ QA I R G ++T + H + + ++ Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALIS---------RTNGSLCHATAMCHHRINEFEEAVN 1325 Query: 557 KDLTDMDKNSP---EAWCAAGNCFSLQREHDIAIKF----FQRAIQVDPNYAYAYTLLGH 609 T K +P +A+ GN + ++ HD A K F +A+ ++P Y A G+ Sbjct: 1326 F-FTWALKINPCFLDAYVGRGNSY-MEYGHDEATKQAQKDFLKALHINPAYIKARISFGY 1383 Query: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGL---------------------------- 641 + KA F AI +P++Y A+ G Sbjct: 1384 NLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAE 1443 Query: 642 -----GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696 G+I+ A +Q A+ +NP+ S+ + G + ++ +A D +KA+ Sbjct: 1444 FLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKAL 1503 Query: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756 DP+N +RA +KY+ A ++ + + P + VYF Y L Q LA Sbjct: 1504 KFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELA 1563 Query: 757 LMNFSWAMDLDPKGA 771 + + A+ L P A Sbjct: 1564 EEDLNKALSLKPNDA 1578 Score = 52.4 bits (124), Expect = 2e-06 Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 4/199 (2%) Query: 552 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 611 + +L++++ D K A+C G + + A+ QR I ++P + AY + Sbjct: 902 VKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIY 961 Query: 612 VLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671 + +++++AL + N + A+ IY ++ +LA +++ +A+ P + + Sbjct: 962 LFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADI 1021 Query: 672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ 731 G + K A+D +K I DPK R NE + +A+++ L Sbjct: 1022 YFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080 Query: 732 IVPKESLV---YFLIGKVY 747 I + S Y L+ K Y Sbjct: 1081 IDHQNSQARGQYLLMMKYY 1099 Score = 49.7 bits (117), Expect = 1e-05 Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 10/152 (6%) Query: 557 KDLTDMDKNSPE---AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 KD D +P+ A+ AGN + R+ A +F +A++ DP Y + Sbjct: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522 Query: 614 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL- 672 ++ ++A F N I P ++ YY +++ LAE KAL + P +++ Sbjct: 1523 LKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN 1582 Query: 673 ------CHIGVVQHALKKSEKALDTLNKAIVI 698 IG+++ A+ +ALD + A VI Sbjct: 1583 FRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 4/128 (3%) Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704 YY+ E L E + D + C G + L K + A++ L + I+++P Sbjct: 897 YYESEVKILTE----EINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLN 952 Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 764 +HR + +K AL +L + + + Y ++Y+ LA++N++ A+ Sbjct: 953 AYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAI 1012 Query: 765 DLDPKGAN 772 P A+ Sbjct: 1013 KSTPTDAD 1020 Score = 39.3 bits (90), Expect = 0.015 Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 21/194 (10%) Query: 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT 542 E IN + P+ Y C+ G Y +L + A V +E ++ Sbjct: 907 EEINDKTKYPAFAY------CRRGAIYRKLGKLQSAMNDLQRVILLE-------PLFLNA 953 Query: 543 LWHLQKDVALS-VLSKDLTDMD------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595 WH +++ L D++ KN+ EA+ + + +++ +AI + +AI+ Sbjct: 954 YWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIK 1013 Query: 596 VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655 P A Y G + +T ++ A+ F I +P+ +A G+ Y + E + A Sbjct: 1014 STPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAI 1072 Query: 656 MHFQKALDINPQSS 669 F L+I+ Q+S Sbjct: 1073 EDFTALLNIDHQNS 1086 >gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo sapiens] Length = 1614 Score = 82.0 bits (201), Expect = 2e-15 Identities = 52/194 (26%), Positives = 99/194 (51%), Gaps = 8/194 (4%) Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633 GN F+ ++ + A+K A + N + +GH+ A+ +++AI +NP+ Sbjct: 1423 GNNFAAMQDINAAMKISTTA-EFLTNRGVIHEFMGHK-------QNAMKDYQDAITLNPK 1474 Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 + A++ G IY+ +FS A +F KAL +P++ +L + + LKK E+A + Sbjct: 1475 YSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFA 1534 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753 I P F+RA + ++Y+ A ++L + + P ++LVY KV K+G Sbjct: 1535 NVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLI 1594 Query: 754 HLALMNFSWAMDLD 767 A+ +++ A+DL+ Sbjct: 1595 EEAMADYNQALDLE 1608 Score = 65.5 bits (158), Expect = 2e-10 Identities = 58/221 (26%), Positives = 93/221 (42%), Gaps = 4/221 (1%) Query: 572 AAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH---EFVLTEELDKALACFRNAI 628 A C E + A+ FF A++++P + AY G+ E+ E +A F A+ Sbjct: 1309 ATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKAL 1368 Query: 629 RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688 +NP + A G Q KF A HF A+D +P++ + VV + + A Sbjct: 1369 HINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAA 1428 Query: 689 LDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 748 + +N A+ I F K ++A+++ ++ + PK SL YF G +Y Sbjct: 1429 MQDINAAMKISTTAEFLTNRGVIHEFMGHK-QNAMKDYQDAITLNPKYSLAYFNAGNIYF 1487 Query: 749 KLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEE 789 Q A FS A+ DP+ + AI L EE Sbjct: 1488 HHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEE 1528 Score = 59.7 bits (143), Expect = 1e-08 Identities = 71/315 (22%), Positives = 126/315 (40%), Gaps = 51/315 (16%) Query: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556 N G + ++G+ F L ++ QA I R G ++T + H + + ++ Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALIS---------RTNGSLCHATAMCHHRINEFEEAVN 1325 Query: 557 KDLTDMDKNSP---EAWCAAGNCFSLQREHDIAIKF----FQRAIQVDPNYAYAYTLLGH 609 T K +P +A+ GN + ++ HD A K F +A+ ++P Y A G+ Sbjct: 1326 F-FTWALKINPCFLDAYVGRGNSY-MEYGHDEATKQAQKDFLKALHINPAYIKARISFGY 1383 Query: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGL---------------------------- 641 + KA F AI +P++Y A+ G Sbjct: 1384 NLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAE 1443 Query: 642 -----GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696 G+I+ A +Q A+ +NP+ S+ + G + ++ +A D +KA+ Sbjct: 1444 FLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKAL 1503 Query: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756 DP+N +RA +KY+ A ++ + + P + VYF Y L Q LA Sbjct: 1504 KFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELA 1563 Query: 757 LMNFSWAMDLDPKGA 771 + + A+ L P A Sbjct: 1564 EEDLNKALSLKPNDA 1578 Score = 52.4 bits (124), Expect = 2e-06 Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 4/199 (2%) Query: 552 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 611 + +L++++ D K A+C G + + A+ QR I ++P + AY + Sbjct: 902 VKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIY 961 Query: 612 VLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671 + +++++AL + N + A+ IY ++ +LA +++ +A+ P + + Sbjct: 962 LFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADI 1021 Query: 672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ 731 G + K A+D +K I DPK R NE + +A+++ L Sbjct: 1022 YFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080 Query: 732 IVPKESLV---YFLIGKVY 747 I + S Y L+ K Y Sbjct: 1081 IDHQNSQARGQYLLMMKYY 1099 Score = 49.7 bits (117), Expect = 1e-05 Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 10/152 (6%) Query: 557 KDLTDMDKNSPE---AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 KD D +P+ A+ AGN + R+ A +F +A++ DP Y + Sbjct: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522 Query: 614 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL- 672 ++ ++A F N I P ++ YY +++ LAE KAL + P +++ Sbjct: 1523 LKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN 1582 Query: 673 ------CHIGVVQHALKKSEKALDTLNKAIVI 698 IG+++ A+ +ALD + A VI Sbjct: 1583 FRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 4/128 (3%) Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704 YY+ E L E + D + C G + L K + A++ L + I+++P Sbjct: 897 YYESEVKILTE----EINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLN 952 Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 764 +HR + +K AL +L + + + Y ++Y+ LA++N++ A+ Sbjct: 953 AYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAI 1012 Query: 765 DLDPKGAN 772 P A+ Sbjct: 1013 KSTPTDAD 1020 Score = 39.3 bits (90), Expect = 0.015 Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 21/194 (10%) Query: 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT 542 E IN + P+ Y C+ G Y +L + A V +E ++ Sbjct: 907 EEINDKTKYPAFAY------CRRGAIYRKLGKLQSAMNDLQRVILLE-------PLFLNA 953 Query: 543 LWHLQKDVALS-VLSKDLTDMD------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595 WH +++ L D++ KN+ EA+ + + +++ +AI + +AI+ Sbjct: 954 YWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIK 1013 Query: 596 VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655 P A Y G + +T ++ A+ F I +P+ +A G+ Y + E + A Sbjct: 1014 STPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAI 1072 Query: 656 MHFQKALDINPQSS 669 F L+I+ Q+S Sbjct: 1073 EDFTALLNIDHQNS 1086 >gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo sapiens] Length = 1614 Score = 82.0 bits (201), Expect = 2e-15 Identities = 52/194 (26%), Positives = 99/194 (51%), Gaps = 8/194 (4%) Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633 GN F+ ++ + A+K A + N + +GH+ A+ +++AI +NP+ Sbjct: 1423 GNNFAAMQDINAAMKISTTA-EFLTNRGVIHEFMGHK-------QNAMKDYQDAITLNPK 1474 Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 + A++ G IY+ +FS A +F KAL +P++ +L + + LKK E+A + Sbjct: 1475 YSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFA 1534 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753 I P F+RA + ++Y+ A ++L + + P ++LVY KV K+G Sbjct: 1535 NVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYNFRAKVRGKIGLI 1594 Query: 754 HLALMNFSWAMDLD 767 A+ +++ A+DL+ Sbjct: 1595 EEAMADYNQALDLE 1608 Score = 65.5 bits (158), Expect = 2e-10 Identities = 58/221 (26%), Positives = 93/221 (42%), Gaps = 4/221 (1%) Query: 572 AAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH---EFVLTEELDKALACFRNAI 628 A C E + A+ FF A++++P + AY G+ E+ E +A F A+ Sbjct: 1309 ATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKAL 1368 Query: 629 RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688 +NP + A G Q KF A HF A+D +P++ + VV + + A Sbjct: 1369 HINPAYIKARISFGYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAA 1428 Query: 689 LDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK 748 + +N A+ I F K ++A+++ ++ + PK SL YF G +Y Sbjct: 1429 MQDINAAMKISTTAEFLTNRGVIHEFMGHK-QNAMKDYQDAITLNPKYSLAYFNAGNIYF 1487 Query: 749 KLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEE 789 Q A FS A+ DP+ + AI L EE Sbjct: 1488 HHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEE 1528 Score = 59.7 bits (143), Expect = 1e-08 Identities = 71/315 (22%), Positives = 126/315 (40%), Gaps = 51/315 (16%) Query: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556 N G + ++G+ F L ++ QA I R G ++T + H + + ++ Sbjct: 1275 NRGLIYVELGQYGFALEDFKQAALIS---------RTNGSLCHATAMCHHRINEFEEAVN 1325 Query: 557 KDLTDMDKNSP---EAWCAAGNCFSLQREHDIAIKF----FQRAIQVDPNYAYAYTLLGH 609 T K +P +A+ GN + ++ HD A K F +A+ ++P Y A G+ Sbjct: 1326 F-FTWALKINPCFLDAYVGRGNSY-MEYGHDEATKQAQKDFLKALHINPAYIKARISFGY 1383 Query: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGL---------------------------- 641 + KA F AI +P++Y A+ G Sbjct: 1384 NLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAE 1443 Query: 642 -----GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696 G+I+ A +Q A+ +NP+ S+ + G + ++ +A D +KA+ Sbjct: 1444 FLTNRGVIHEFMGHKQNAMKDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKAL 1503 Query: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756 DP+N +RA +KY+ A ++ + + P + VYF Y L Q LA Sbjct: 1504 KFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELA 1563 Query: 757 LMNFSWAMDLDPKGA 771 + + A+ L P A Sbjct: 1564 EEDLNKALSLKPNDA 1578 Score = 52.4 bits (124), Expect = 2e-06 Identities = 43/199 (21%), Positives = 86/199 (43%), Gaps = 4/199 (2%) Query: 552 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 611 + +L++++ D K A+C G + + A+ QR I ++P + AY + Sbjct: 902 VKILTEEINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLNAYWHRHLIY 961 Query: 612 VLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671 + +++++AL + N + A+ IY ++ +LA +++ +A+ P + + Sbjct: 962 LFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIKSTPTDADI 1021 Query: 672 LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ 731 G + K A+D +K I DPK R NE + +A+++ L Sbjct: 1022 YFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAIEDFTALLN 1080 Query: 732 IVPKESLV---YFLIGKVY 747 I + S Y L+ K Y Sbjct: 1081 IDHQNSQARGQYLLMMKYY 1099 Score = 49.7 bits (117), Expect = 1e-05 Identities = 38/152 (25%), Positives = 67/152 (44%), Gaps = 10/152 (6%) Query: 557 KDLTDMDKNSPE---AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 KD D +P+ A+ AGN + R+ A +F +A++ DP Y + Sbjct: 1463 KDYQDAITLNPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTI 1522 Query: 614 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL- 672 ++ ++A F N I P ++ YY +++ LAE KAL + P +++ Sbjct: 1523 LKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN 1582 Query: 673 ------CHIGVVQHALKKSEKALDTLNKAIVI 698 IG+++ A+ +ALD + A VI Sbjct: 1583 FRAKVRGKIGLIEEAMADYNQALDLEDYASVI 1614 Score = 42.0 bits (97), Expect = 0.002 Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 4/128 (3%) Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704 YY+ E L E + D + C G + L K + A++ L + I+++P Sbjct: 897 YYESEVKILTE----EINDKTKYPAFAYCRRGAIYRKLGKLQSAMNDLQRVILLEPLFLN 952 Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 764 +HR + +K AL +L + + + Y ++Y+ LA++N++ A+ Sbjct: 953 AYWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAI 1012 Query: 765 DLDPKGAN 772 P A+ Sbjct: 1013 KSTPTDAD 1020 Score = 39.3 bits (90), Expect = 0.015 Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 21/194 (10%) Query: 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT 542 E IN + P+ Y C+ G Y +L + A V +E ++ Sbjct: 907 EEINDKTKYPAFAY------CRRGAIYRKLGKLQSAMNDLQRVILLE-------PLFLNA 953 Query: 543 LWHLQKDVALS-VLSKDLTDMD------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595 WH +++ L D++ KN+ EA+ + + +++ +AI + +AI+ Sbjct: 954 YWHRHLIYLFQDKINEALDDLNYIHKYNKNNTEAYLSKAEIYRGKKDITLAILNYTQAIK 1013 Query: 596 VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655 P A Y G + +T ++ A+ F I +P+ +A G+ Y + E + A Sbjct: 1014 STPTDADIYFRRGEMYEITNKV-LAIDDFSKCIFYDPKRTDALLKRGLFYCENENWFAAI 1072 Query: 656 MHFQKALDINPQSS 669 F L+I+ Q+S Sbjct: 1073 EDFTALLNIDHQNS 1086 >gi|118402578 anaphase-promoting complex, subunit 6 [Homo sapiens] Length = 620 Score = 80.5 bits (197), Expect = 6e-15 Identities = 68/278 (24%), Positives = 122/278 (43%), Gaps = 14/278 (5%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 V+ + ++ ++ ++ S V + + + ++ TL L K L LS L Sbjct: 233 VVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLV 292 Query: 561 DMDKNSPEAWCAAGNCFSLQREH--DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD 618 D+ ++P +W A G C+ L H + A ++ +A ++ Y A+ GH F + E D Sbjct: 293 DLYPSNPVSWFAVG-CYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHD 351 Query: 619 KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVV 678 +A+A + A ++ + +G+ Y LAE F +AL I P+ ++ +GVV Sbjct: 352 QAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVV 411 Query: 679 ---QHALKKSEK-ALDTLNK------AIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728 K +EK LD L K + +D PL + V +KY AL + Sbjct: 412 AFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLN-NLGHVCRKLKKYAEALDYHRQ 470 Query: 729 LKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766 ++P+ + Y IG ++ +G A+ F A+ L Sbjct: 471 ALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL 508 >gi|118402580 anaphase-promoting complex, subunit 6 [Homo sapiens] Length = 620 Score = 80.5 bits (197), Expect = 6e-15 Identities = 68/278 (24%), Positives = 122/278 (43%), Gaps = 14/278 (5%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 V+ + ++ ++ ++ S V + + + ++ TL L K L LS L Sbjct: 233 VVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVELNKANELFYLSHKLV 292 Query: 561 DMDKNSPEAWCAAGNCFSLQREH--DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD 618 D+ ++P +W A G C+ L H + A ++ +A ++ Y A+ GH F + E D Sbjct: 293 DLYPSNPVSWFAVG-CYYLMVGHKNEHARRYLSKATTLEKTYGPAWIAYGHSFAVESEHD 351 Query: 619 KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVV 678 +A+A + A ++ + +G+ Y LAE F +AL I P+ ++ +GVV Sbjct: 352 QAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVV 411 Query: 679 ---QHALKKSEK-ALDTLNK------AIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728 K +EK LD L K + +D PL + V +KY AL + Sbjct: 412 AFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLN-NLGHVCRKLKKYAEALDYHRQ 470 Query: 729 LKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766 ++P+ + Y IG ++ +G A+ F A+ L Sbjct: 471 ALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL 508 >gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] Length = 1036 Score = 77.0 bits (188), Expect = 7e-14 Identities = 53/222 (23%), Positives = 103/222 (46%), Gaps = 6/222 (2%) Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 N AW G F+ Q E +AI F++A+ +DPN+ AY LG+ D+A+A + Sbjct: 179 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 238 Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 684 A+ ++P H L +YY+Q LA +++A+++ P C++ Sbjct: 239 LRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGS 298 Query: 685 SEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744 +A D N A+ + P + + A++ + A++ + ++ P+ + + + Sbjct: 299 VAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLA 358 Query: 745 KVYKKLGQTHLALMNFSWAMDLDPKGAN------NQIKEAID 780 V ++ G+ ALM++ A+ + P A+ N +KE D Sbjct: 359 SVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD 400 Score = 65.9 bits (159), Expect = 2e-10 Identities = 51/211 (24%), Positives = 96/211 (45%) Query: 562 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL 621 +D N +A+ GN R D A+ + RA+ + PN+A + L + +D A+ Sbjct: 210 LDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAI 269 Query: 622 ACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHA 681 +R AI + P +A+ L ++ + AE + AL + P + L ++ ++ Sbjct: 270 DTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKRE 329 Query: 682 LKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYF 741 E+A+ KA+ + P+ + ASVL K + AL +E +I P + Y Sbjct: 330 QGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYS 389 Query: 742 LIGKVYKKLGQTHLALMNFSWAMDLDPKGAN 772 +G K++ AL ++ A+ ++P A+ Sbjct: 390 NMGNTLKEMQDVQGALQCYTRAIQINPAFAD 420 Score = 60.8 bits (146), Expect = 5e-09 Identities = 44/201 (21%), Positives = 92/201 (45%) Query: 568 EAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNA 627 EA+ GN + + + AI+ ++ A+++ P++ Y L V +++ A+ + +A Sbjct: 80 EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 139 Query: 628 IRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687 ++ NP Y LG + + A+ + KA++ P +V ++G V +A + Sbjct: 140 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWL 199 Query: 688 ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVY 747 A+ KA+ +DP + +VL + A+ + P ++V+ + VY Sbjct: 200 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 259 Query: 748 KKLGQTHLALMNFSWAMDLDP 768 + G LA+ + A++L P Sbjct: 260 YEQGLIDLAIDTYRRAIELQP 280 Score = 60.1 bits (144), Expect = 8e-09 Identities = 55/237 (23%), Positives = 100/237 (42%), Gaps = 7/237 (2%) Query: 555 LSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLT 614 L D D N A AAG+ + A++ + A+Q +P+ + LG+ Sbjct: 108 LKPDFIDGYINLAAALVAAGDM-------EGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 160 Query: 615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCH 674 L++A AC+ AI P AW LG ++ Q + LA HF+KA+ ++P + Sbjct: 161 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN 220 Query: 675 IGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVP 734 +G V + ++A+ +A+ + P + + + A V + A+ ++ P Sbjct: 221 LGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP 280 Query: 735 KESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI 791 Y + K+ G A ++ A+ L P A++ A KR + EE + Sbjct: 281 HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAV 337 Score = 59.3 bits (142), Expect = 1e-08 Identities = 45/185 (24%), Positives = 85/185 (45%) Query: 584 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 643 D+AI ++RAI++ P++ AY L + + +A C+ A+R+ P H ++ L Sbjct: 266 DLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLAN 325 Query: 644 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNP 703 I +Q A ++KAL++ P+ + ++ V K ++AL +AI I P Sbjct: 326 IKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA 385 Query: 704 LCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWA 763 + + L + + ALQ QI P + + + ++K G A+ ++ A Sbjct: 386 DAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTA 445 Query: 764 MDLDP 768 + L P Sbjct: 446 LKLKP 450 Score = 50.4 bits (119), Expect = 7e-06 Identities = 46/191 (24%), Positives = 78/191 (40%) Query: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640 R D + F AI+ +P A AY+ LG+ + +L +A+ +R+A+R+ P + + Sbjct: 59 RRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYIN 118 Query: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700 L A + AL NP + +G + AL + E+A KAI P Sbjct: 119 LAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQP 178 Query: 701 KNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNF 760 + + V A + A+ E+ + P Y +G V K+ A+ + Sbjct: 179 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 238 Query: 761 SWAMDLDPKGA 771 A+ L P A Sbjct: 239 LRALSLSPNHA 249 Score = 47.0 bits (110), Expect = 7e-05 Identities = 49/216 (22%), Positives = 93/216 (43%), Gaps = 25/216 (11%) Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRR 527 E G LA+ +Y + AI + H P + C + A E +AE ++ R Sbjct: 261 EQGLIDLAIDTY--RRAIELQPHFPDAY-------CNLANALKEKGSVAEAEDCYNTALR 311 Query: 528 IENYRVEGMEIYSTTLWHLQKDV-----ALSVLSKDLTDMDKNSPEAWCAAGNCFS-LQR 581 + + + L +++++ A+ + K L PE A N S LQ+ Sbjct: 312 LCPTHADSLN----NLANIKREQGNIEEAVRLYRKALEVF----PEFAAAHSNLASVLQQ 363 Query: 582 EHDI--AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWY 639 + + A+ ++ AI++ P +A AY+ +G+ +++ AL C+ AI++NP +A Sbjct: 364 QGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHS 423 Query: 640 GLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 L I+ A ++ AL + P C++ Sbjct: 424 NLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNL 459 Score = 40.4 bits (93), Expect = 0.007 Identities = 41/188 (21%), Positives = 76/188 (40%), Gaps = 6/188 (3%) Query: 597 DPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM 656 +P+ LL LD++ AI+ NP A+ LG +Y ++ + A Sbjct: 41 EPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIE 100 Query: 657 HFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFAN 716 H++ AL + P ++ A E A+ A+ +P + ++L A Sbjct: 101 HYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 160 Query: 717 EKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK------G 770 + + A + + P ++ + +G V+ G+ LA+ +F A+ LDP Sbjct: 161 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN 220 Query: 771 ANNQIKEA 778 N +KEA Sbjct: 221 LGNVLKEA 228 >gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] Length = 1046 Score = 77.0 bits (188), Expect = 7e-14 Identities = 53/222 (23%), Positives = 103/222 (46%), Gaps = 6/222 (2%) Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 N AW G F+ Q E +AI F++A+ +DPN+ AY LG+ D+A+A + Sbjct: 189 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 248 Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 684 A+ ++P H L +YY+Q LA +++A+++ P C++ Sbjct: 249 LRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGS 308 Query: 685 SEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744 +A D N A+ + P + + A++ + A++ + ++ P+ + + + Sbjct: 309 VAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLA 368 Query: 745 KVYKKLGQTHLALMNFSWAMDLDPKGAN------NQIKEAID 780 V ++ G+ ALM++ A+ + P A+ N +KE D Sbjct: 369 SVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD 410 Score = 65.9 bits (159), Expect = 2e-10 Identities = 51/211 (24%), Positives = 96/211 (45%) Query: 562 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL 621 +D N +A+ GN R D A+ + RA+ + PN+A + L + +D A+ Sbjct: 220 LDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAI 279 Query: 622 ACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHA 681 +R AI + P +A+ L ++ + AE + AL + P + L ++ ++ Sbjct: 280 DTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKRE 339 Query: 682 LKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYF 741 E+A+ KA+ + P+ + ASVL K + AL +E +I P + Y Sbjct: 340 QGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYS 399 Query: 742 LIGKVYKKLGQTHLALMNFSWAMDLDPKGAN 772 +G K++ AL ++ A+ ++P A+ Sbjct: 400 NMGNTLKEMQDVQGALQCYTRAIQINPAFAD 430 Score = 60.8 bits (146), Expect = 5e-09 Identities = 44/201 (21%), Positives = 92/201 (45%) Query: 568 EAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNA 627 EA+ GN + + + AI+ ++ A+++ P++ Y L V +++ A+ + +A Sbjct: 90 EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 149 Query: 628 IRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687 ++ NP Y LG + + A+ + KA++ P +V ++G V +A + Sbjct: 150 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWL 209 Query: 688 ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVY 747 A+ KA+ +DP + +VL + A+ + P ++V+ + VY Sbjct: 210 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 269 Query: 748 KKLGQTHLALMNFSWAMDLDP 768 + G LA+ + A++L P Sbjct: 270 YEQGLIDLAIDTYRRAIELQP 290 Score = 60.1 bits (144), Expect = 8e-09 Identities = 55/237 (23%), Positives = 100/237 (42%), Gaps = 7/237 (2%) Query: 555 LSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLT 614 L D D N A AAG+ + A++ + A+Q +P+ + LG+ Sbjct: 118 LKPDFIDGYINLAAALVAAGDM-------EGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 170 Query: 615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCH 674 L++A AC+ AI P AW LG ++ Q + LA HF+KA+ ++P + Sbjct: 171 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN 230 Query: 675 IGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVP 734 +G V + ++A+ +A+ + P + + + A V + A+ ++ P Sbjct: 231 LGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP 290 Query: 735 KESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI 791 Y + K+ G A ++ A+ L P A++ A KR + EE + Sbjct: 291 HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAV 347 Score = 59.3 bits (142), Expect = 1e-08 Identities = 45/185 (24%), Positives = 85/185 (45%) Query: 584 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 643 D+AI ++RAI++ P++ AY L + + +A C+ A+R+ P H ++ L Sbjct: 276 DLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLAN 335 Query: 644 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNP 703 I +Q A ++KAL++ P+ + ++ V K ++AL +AI I P Sbjct: 336 IKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFA 395 Query: 704 LCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWA 763 + + L + + ALQ QI P + + + ++K G A+ ++ A Sbjct: 396 DAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTA 455 Query: 764 MDLDP 768 + L P Sbjct: 456 LKLKP 460 Score = 50.4 bits (119), Expect = 7e-06 Identities = 46/191 (24%), Positives = 78/191 (40%) Query: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640 R D + F AI+ +P A AY+ LG+ + +L +A+ +R+A+R+ P + + Sbjct: 69 RRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYIN 128 Query: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700 L A + AL NP + +G + AL + E+A KAI P Sbjct: 129 LAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQP 188 Query: 701 KNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNF 760 + + V A + A+ E+ + P Y +G V K+ A+ + Sbjct: 189 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 248 Query: 761 SWAMDLDPKGA 771 A+ L P A Sbjct: 249 LRALSLSPNHA 259 Score = 47.0 bits (110), Expect = 7e-05 Identities = 49/216 (22%), Positives = 93/216 (43%), Gaps = 25/216 (11%) Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRR 527 E G LA+ +Y + AI + H P + C + A E +AE ++ R Sbjct: 271 EQGLIDLAIDTY--RRAIELQPHFPDAY-------CNLANALKEKGSVAEAEDCYNTALR 321 Query: 528 IENYRVEGMEIYSTTLWHLQKDV-----ALSVLSKDLTDMDKNSPEAWCAAGNCFS-LQR 581 + + + L +++++ A+ + K L PE A N S LQ+ Sbjct: 322 LCPTHADSLN----NLANIKREQGNIEEAVRLYRKALEVF----PEFAAAHSNLASVLQQ 373 Query: 582 EHDI--AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWY 639 + + A+ ++ AI++ P +A AY+ +G+ +++ AL C+ AI++NP +A Sbjct: 374 QGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHS 433 Query: 640 GLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 L I+ A ++ AL + P C++ Sbjct: 434 NLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNL 469 Score = 40.4 bits (93), Expect = 0.007 Identities = 41/188 (21%), Positives = 76/188 (40%), Gaps = 6/188 (3%) Query: 597 DPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM 656 +P+ LL LD++ AI+ NP A+ LG +Y ++ + A Sbjct: 51 EPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIE 110 Query: 657 HFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFAN 716 H++ AL + P ++ A E A+ A+ +P + ++L A Sbjct: 111 HYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 170 Query: 717 EKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK------G 770 + + A + + P ++ + +G V+ G+ LA+ +F A+ LDP Sbjct: 171 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN 230 Query: 771 ANNQIKEA 778 N +KEA Sbjct: 231 LGNVLKEA 238 >gi|212549736 anaphase-promoting complex subunit 7 isoform a [Homo sapiens] Length = 599 Score = 68.2 bits (165), Expect = 3e-11 Identities = 67/318 (21%), Positives = 129/318 (40%), Gaps = 8/318 (2%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 +L + YF + + F + + ++ Y ++GM++Y L + + L L Sbjct: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332 Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620 ++ E W +G + + A+ +AIQ++ N A L G + +A Sbjct: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392 Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIGV 677 + FR AIR+ P + + GL Y A + + K L N Q+ LL + + Sbjct: 393 IIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCL 452 Query: 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKES 737 + EKA L+KA+ P +A +L +KY+ + L + Sbjct: 453 EDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRN-ALANQSDC 509 Query: 738 LVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQI 797 +++ ++G + + A+ +S A+ LDP + + E + K + TQEE + Sbjct: 510 VLHRILGDFLVAVNEYQEAMDQYSIALSLDPN--DQKSLEGMQKMEKEESPTDATQEEDV 567 Query: 798 MGTDESQESSMTDADDTQ 815 + S E + D++ Sbjct: 568 DDMEGSGEEGDLEGSDSE 585 >gi|83415184 transmembrane and tetratricopeptide repeat containing 1 [Homo sapiens] Length = 774 Score = 62.8 bits (151), Expect = 1e-09 Identities = 54/209 (25%), Positives = 92/209 (44%), Gaps = 15/209 (7%) Query: 567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRN 626 P A N +L R+ A ++QRA+Q+ P + A LG+ E+ ++A+ ++ Sbjct: 406 PRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKD 465 Query: 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSE 686 +I+ P +A+ L + +QE+F AE +Q + P SS L + GV E Sbjct: 466 SIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDTGLPE 525 Query: 687 KALDTLNKAIVIDPKNPLCKFHRASVL-------FANEKYKSALQELEELKQIVPKESLV 739 KA+ +AI + P + + + + A E YK ALQ + + + P Sbjct: 526 KAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAHKAEILSP----- 580 Query: 740 YFLIGKVYKKLGQTHLALMNFSWAMDLDP 768 +G +Y G+ AL + A L P Sbjct: 581 ---LGALYYNTGRYEEALQIYQEAAALQP 606 Score = 60.1 bits (144), Expect = 8e-09 Identities = 39/175 (22%), Positives = 78/175 (44%), Gaps = 4/175 (2%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 +L +G Y+ Y +A +I+ E ++ + E + L + + ++ + Sbjct: 577 ILSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIV 636 Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLL----GHEFVLTEE 616 + E + +S Q HD A+ +A+Q+ P + L G++ Sbjct: 637 SEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNL 696 Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671 LDKA +R A+++NP AW +G I + + K+ A ++++AL + P S +L Sbjct: 697 LDKAFESYRVAVQLNPDQAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLL 751 Score = 58.5 bits (140), Expect = 2e-08 Identities = 54/227 (23%), Positives = 103/227 (45%), Gaps = 10/227 (4%) Query: 547 QKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL 606 +K+ A+++L KD +A+ + + + Q A + +Q I+ P+ + + Sbjct: 455 KKEEAITLL-KDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNN 513 Query: 607 LGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666 G V T +KA+A ++ AI+++P H+ A LG +Y + S+AE +++AL + Sbjct: 514 YGVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAH 573 Query: 667 QSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQEL 726 ++ + L +G + + + E+AL +A + P + A VL + K E Sbjct: 574 KAEI-LSPLGALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTK----EA 628 Query: 727 EELKQIVPKESL----VYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769 E++ + E Y L+ +Y K AL A+ L PK Sbjct: 629 EKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKALQLKPK 675 Score = 44.3 bits (103), Expect = 5e-04 Identities = 47/244 (19%), Positives = 94/244 (38%), Gaps = 13/244 (5%) Query: 492 PSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVA 551 PSHH + +GR Y L E AE + ++ ++ E + ++ + Sbjct: 539 PSHHV----AMVNLGRLYRSLGENSMAEEWYKRALQVA-HKAEILSPLGALYYNTGRYEE 593 Query: 552 LSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEF 611 + ++ + + E A ++ + A K + + Y LL + Sbjct: 594 ALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIY 653 Query: 612 VLTEELDKALACFRNAIRVNPRHYNA----WYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667 E DKAL A+++ P+ ++ G +Q A ++ A+ +NP Sbjct: 654 SKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPD 713 Query: 668 SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELE 727 + ++G +QH K A +A+ + P + L K + A + ++ + LQE+ Sbjct: 714 QAQAWMNMGGIQHIKGKYVSARAYYERALQLVPDSKLLKENLAKL----DRLEKRLQEVR 769 Query: 728 ELKQ 731 E Q Sbjct: 770 EKDQ 773 Score = 38.9 bits (89), Expect = 0.020 Identities = 46/214 (21%), Positives = 89/214 (41%), Gaps = 12/214 (5%) Query: 564 KNSPEAWCAAGNCFSLQR---EHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620 K SP A N L R E+ +A ++++RA+QV + A + LG + T ++A Sbjct: 536 KLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQV-AHKAEILSPLGALYYNTGRYEEA 594 Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCH--IGVV 678 L ++ A + P L + + AE ++ ++ L C+ + + Sbjct: 595 LQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHI--VSEETGCLECYRLLSAI 652 Query: 679 QHALKKSEKALDTLNKAIVIDPKNPL----CKFHRASVLFANEKYKSALQELEELKQIVP 734 + +KALD ++KA+ + PK+P F + + L A + Q+ P Sbjct: 653 YSKQENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNP 712 Query: 735 KESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP 768 ++ + +G + G+ A + A+ L P Sbjct: 713 DQAQAWMNMGGIQHIKGKYVSARAYYERALQLVP 746 Score = 32.0 bits (71), Expect = 2.4 Identities = 23/117 (19%), Positives = 55/117 (47%), Gaps = 3/117 (2%) Query: 624 FRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALK 683 FR+ ++ P + Y Q + A H++ AL + P+ + L ++G + + Sbjct: 364 FRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHYRTALKLYPRHASALNNLGTL---TR 420 Query: 684 KSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVY 740 + +A +A+ + P++ F+ ++L + EK + A+ L++ + P+ + Y Sbjct: 421 DTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAITLLKDSIKYGPEFADAY 477 >gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] Length = 519 Score = 57.8 bits (138), Expect = 4e-08 Identities = 71/337 (21%), Positives = 140/337 (41%), Gaps = 41/337 (12%) Query: 422 NINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYNC 481 NI +SLE+ + + ++PQ A NL++ A + +GK A+ YN Sbjct: 82 NIQESLELFQT---------CAVLSPQ-SADNLKQVARSLFL-----LGKHKAAIEVYNE 126 Query: 482 KEAINILSHLPSHHYNTGWV-LCQIGRAYFELSEYMQAER------IFSEVRRIENYRVE 534 +N SH+ ++ L Q +A +L + R + ++ +E + Sbjct: 127 AAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIMLGKIHLLEGDLDK 186 Query: 535 GMEIYSTT---------------LWHLQKDV---ALSVLSKDLTDMDKNSPEAWCAAGNC 576 +E+Y L +LQ + A L LT D + +A AAG+ Sbjct: 187 AIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALT-YDPTNYKAILAAGSM 245 Query: 577 FSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYN 636 + D+A+ ++ P + +G F ++ A++C + A + P + Sbjct: 246 MQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGKKKYVAAISCLKRANYLAPFDWK 305 Query: 637 AWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696 Y LG+++ ++++ A A++ P+ L + V L+ E A +A+ Sbjct: 306 ILYNLGLVHLTMQQYASAFHFLSAAINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAV 365 Query: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIV 733 +D NPL + A +L+ + K+AL + +E+++ V Sbjct: 366 HLDKCNPLVNLNYAVLLYNQGEKKNALAQYQEMEKKV 402 Score = 56.6 bits (135), Expect = 9e-08 Identities = 60/274 (21%), Positives = 109/274 (39%), Gaps = 17/274 (6%) Query: 502 LCQIGRAYFELSEYMQAERIFSEVRRIE------NYRVEGMEIYSTTLWHLQKDV--ALS 553 L Q+ R+ F L ++ A +++E ++ ++ + IY Q + AL+ Sbjct: 104 LKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNALN 163 Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 + DLT + G L+ + D AI+ +++A++ P T LG ++ Sbjct: 164 LNRHDLT---------YIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQ 214 Query: 614 TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLC 673 KA NA+ +P +Y A G + F +A ++ P+S L Sbjct: 215 LGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWN 274 Query: 674 HIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIV 733 +IG+ KK A+ L +A + P + ++ V ++Y SA L Sbjct: 275 NIGMCFFGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQ 334 Query: 734 PKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD 767 PK +Y L+ L A ++ A+ LD Sbjct: 335 PKMGELYMLLAVALTNLEDIENAKRAYAEAVHLD 368 Score = 53.9 bits (128), Expect = 6e-07 Identities = 46/236 (19%), Positives = 99/236 (41%), Gaps = 1/236 (0%) Query: 534 EGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRA 593 + ++ + +L+ L K A + + +++ E G C+ ++ + A A Sbjct: 102 DNLKQVARSLFLLGKHKAAIEVYNEAAKLNQKDWEISHNLGVCYIYLKQFNKAQDQLHNA 161 Query: 594 IQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSL 653 + ++ + Y +LG +L +LDKA+ ++ A+ +P + LG++Y + + Sbjct: 162 LNLN-RHDLTYIMLGKIHLLEGDLDKAIEVYKKAVEFSPENTELLTTLGLLYLQLGIYQK 220 Query: 654 AEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVL 713 A H AL +P + + G + + AL P++P + Sbjct: 221 AFEHLGNALTYDPTNYKAILAAGSMMQTHGDFDVALTKYRVVACAVPESPPLWNNIGMCF 280 Query: 714 FANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769 F +KY +A+ L+ + P + + + +G V+ + Q A S A++ PK Sbjct: 281 FGKKKYVAAISCLKRANYLAPFDWKILYNLGLVHLTMQQYASAFHFLSAAINFQPK 336 >gi|118766328 transmembrane and tetratricopeptide repeat containing 4 isoform 2 [Homo sapiens] Length = 741 Score = 57.8 bits (138), Expect = 4e-08 Identities = 38/153 (24%), Positives = 70/153 (45%) Query: 588 KFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYK 647 + F+ A+ V P A + +G A+ +R A+R+NP++ +A LG I + Sbjct: 469 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 528 Query: 648 QEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKF 707 + + AE A+ I P + ++G+VQ++LK+ E A + AI K P C + Sbjct: 529 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYY 588 Query: 708 HRASVLFANEKYKSALQELEELKQIVPKESLVY 740 + + ++ AL + P+ SL + Sbjct: 589 NLGRLYADLNRHVDALNAWRNATVLKPEHSLAW 621 Score = 57.0 bits (136), Expect = 7e-08 Identities = 46/233 (19%), Positives = 95/233 (40%), Gaps = 34/233 (14%) Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645 AI++++ A++++P Y +A LG+ EL +A A+++ P AW LG++ Sbjct: 501 AIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQ 560 Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705 ++F AE ++ A+ + ++G + L + AL+ A V+ P++ L Sbjct: 561 NSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLA 620 Query: 706 ----------------------------------KFHRASVLFANEKYKSALQELEELKQ 731 F A+VL ++KYK + + + Sbjct: 621 WNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIK 680 Query: 732 IVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYL 784 P + + + +Y + G LA ++ ++ LDP + + + +R L Sbjct: 681 ANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGLLRRKL 733 Score = 42.4 bits (98), Expect = 0.002 Identities = 50/255 (19%), Positives = 100/255 (39%), Gaps = 28/255 (10%) Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFEL----SEYMQAERIFS 523 ++ + L++C N K NI +L T + R Y E +Y+ A Sbjct: 469 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAI-----RYYREAVRLNPKYVHAMNNLG 523 Query: 524 EVRRIENYRVEGMEIYSTTLWHLQKDVA-----LSVLSKDLTDMD-------------KN 565 + + N E E+ S + +Q D A L ++ L + + Sbjct: 524 NILKERNELQEAEELLSLAV-QIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRK 582 Query: 566 SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFR 625 P+ + G ++ H A+ ++ A + P ++ A+ + T L +A A R Sbjct: 583 YPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGR 642 Query: 626 NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKS 685 A+ + P ++ + L + K +K+ +E F KA+ NP ++ ++ V+ H Sbjct: 643 EALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHL 702 Query: 686 EKALDTLNKAIVIDP 700 + A ++ +DP Sbjct: 703 DLAKKHYEISLQLDP 717 Score = 36.6 bits (83), Expect = 0.097 Identities = 21/97 (21%), Positives = 50/97 (51%) Query: 591 QRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEK 650 + A+++ PN L + +++ ++ A F AI+ NP + L ++Y++ Sbjct: 642 REALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGH 701 Query: 651 FSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687 LA+ H++ +L ++P +S + G+++ L+ +K Sbjct: 702 LDLAKKHYEISLQLDPTASGTKENYGLLRRKLELMQK 738 >gi|118766330 transmembrane and tetratricopeptide repeat containing 4 isoform 1 [Homo sapiens] Length = 760 Score = 57.8 bits (138), Expect = 4e-08 Identities = 38/153 (24%), Positives = 70/153 (45%) Query: 588 KFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYK 647 + F+ A+ V P A + +G A+ +R A+R+NP++ +A LG I + Sbjct: 488 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 547 Query: 648 QEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKF 707 + + AE A+ I P + ++G+VQ++LK+ E A + AI K P C + Sbjct: 548 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYY 607 Query: 708 HRASVLFANEKYKSALQELEELKQIVPKESLVY 740 + + ++ AL + P+ SL + Sbjct: 608 NLGRLYADLNRHVDALNAWRNATVLKPEHSLAW 640 Score = 57.0 bits (136), Expect = 7e-08 Identities = 46/233 (19%), Positives = 95/233 (40%), Gaps = 34/233 (14%) Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645 AI++++ A++++P Y +A LG+ EL +A A+++ P AW LG++ Sbjct: 520 AIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQ 579 Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705 ++F AE ++ A+ + ++G + L + AL+ A V+ P++ L Sbjct: 580 NSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLA 639 Query: 706 ----------------------------------KFHRASVLFANEKYKSALQELEELKQ 731 F A+VL ++KYK + + + Sbjct: 640 WNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIK 699 Query: 732 IVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYL 784 P + + + +Y + G LA ++ ++ LDP + + + +R L Sbjct: 700 ANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGLLRRKL 752 Score = 42.4 bits (98), Expect = 0.002 Identities = 50/255 (19%), Positives = 100/255 (39%), Gaps = 28/255 (10%) Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFEL----SEYMQAERIFS 523 ++ + L++C N K NI +L T + R Y E +Y+ A Sbjct: 488 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAI-----RYYREAVRLNPKYVHAMNNLG 542 Query: 524 EVRRIENYRVEGMEIYSTTLWHLQKDVA-----LSVLSKDLTDMD-------------KN 565 + + N E E+ S + +Q D A L ++ L + + Sbjct: 543 NILKERNELQEAEELLSLAV-QIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRK 601 Query: 566 SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFR 625 P+ + G ++ H A+ ++ A + P ++ A+ + T L +A A R Sbjct: 602 YPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGR 661 Query: 626 NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKS 685 A+ + P ++ + L + K +K+ +E F KA+ NP ++ ++ V+ H Sbjct: 662 EALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHL 721 Query: 686 EKALDTLNKAIVIDP 700 + A ++ +DP Sbjct: 722 DLAKKHYEISLQLDP 736 Score = 36.6 bits (83), Expect = 0.097 Identities = 21/97 (21%), Positives = 50/97 (51%) Query: 591 QRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEK 650 + A+++ PN L + +++ ++ A F AI+ NP + L ++Y++ Sbjct: 661 REALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGH 720 Query: 651 FSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687 LA+ H++ +L ++P +S + G+++ L+ +K Sbjct: 721 LDLAKKHYEISLQLDPTASGTKENYGLLRRKLELMQK 757 >gi|196259776 peroxisomal biogenesis factor 5 isoform d [Homo sapiens] Length = 639 Score = 55.5 bits (132), Expect = 2e-07 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%) Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597 + S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V Sbjct: 462 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 518 Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657 PN + LG + ++A+A +R A+ + P + + Y LG+ A H Sbjct: 519 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 578 Query: 658 FQKALDINPQS 668 F +AL++ +S Sbjct: 579 FLEALNMQRKS 589 Score = 35.8 bits (81), Expect = 0.17 Identities = 20/77 (25%), Positives = 36/77 (46%) Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 +L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L + Sbjct: 350 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 409 Query: 676 GVVQHALKKSEKALDTL 692 V +A +TL Sbjct: 410 AVSFTNESLQRQACETL 426 Score = 30.4 bits (67), Expect = 7.0 Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%) Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 +L + D EAW G + + +AI +R +++ P+ A L F Sbjct: 356 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 415 Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657 +A R+ +R P + + A G LG + + E+ Sbjct: 416 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 474 Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715 F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L Sbjct: 475 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 534 Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770 + + A+ ++ P + +G LG A+ +F A+++ P+G Sbjct: 535 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 594 Query: 771 ANNQIKEAI 779 + E I Sbjct: 595 EGGAMSENI 603 >gi|196259774 peroxisomal biogenesis factor 5 isoform d [Homo sapiens] Length = 639 Score = 55.5 bits (132), Expect = 2e-07 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%) Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597 + S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V Sbjct: 462 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 518 Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657 PN + LG + ++A+A +R A+ + P + + Y LG+ A H Sbjct: 519 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 578 Query: 658 FQKALDINPQS 668 F +AL++ +S Sbjct: 579 FLEALNMQRKS 589 Score = 35.8 bits (81), Expect = 0.17 Identities = 20/77 (25%), Positives = 36/77 (46%) Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 +L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L + Sbjct: 350 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 409 Query: 676 GVVQHALKKSEKALDTL 692 V +A +TL Sbjct: 410 AVSFTNESLQRQACETL 426 Score = 30.4 bits (67), Expect = 7.0 Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%) Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 +L + D EAW G + + +AI +R +++ P+ A L F Sbjct: 356 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 415 Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657 +A R+ +R P + + A G LG + + E+ Sbjct: 416 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 474 Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715 F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L Sbjct: 475 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 534 Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770 + + A+ ++ P + +G LG A+ +F A+++ P+G Sbjct: 535 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 594 Query: 771 ANNQIKEAI 779 + E I Sbjct: 595 EGGAMSENI 603 >gi|196259772 peroxisomal biogenesis factor 5 isoform c [Homo sapiens] Length = 602 Score = 55.5 bits (132), Expect = 2e-07 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%) Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597 + S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V Sbjct: 425 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 481 Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657 PN + LG + ++A+A +R A+ + P + + Y LG+ A H Sbjct: 482 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 541 Query: 658 FQKALDINPQS 668 F +AL++ +S Sbjct: 542 FLEALNMQRKS 552 Score = 35.8 bits (81), Expect = 0.17 Identities = 20/77 (25%), Positives = 36/77 (46%) Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 +L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L + Sbjct: 313 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 372 Query: 676 GVVQHALKKSEKALDTL 692 V +A +TL Sbjct: 373 AVSFTNESLQRQACETL 389 Score = 30.4 bits (67), Expect = 7.0 Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%) Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 +L + D EAW G + + +AI +R +++ P+ A L F Sbjct: 319 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 378 Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657 +A R+ +R P + + A G LG + + E+ Sbjct: 379 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 437 Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715 F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L Sbjct: 438 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 497 Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770 + + A+ ++ P + +G LG A+ +F A+++ P+G Sbjct: 498 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 557 Query: 771 ANNQIKEAI 779 + E I Sbjct: 558 EGGAMSENI 566 >gi|196259770 peroxisomal biogenesis factor 5 isoform a [Homo sapiens] Length = 654 Score = 55.5 bits (132), Expect = 2e-07 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%) Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597 + S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V Sbjct: 477 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 533 Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657 PN + LG + ++A+A +R A+ + P + + Y LG+ A H Sbjct: 534 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 593 Query: 658 FQKALDINPQS 668 F +AL++ +S Sbjct: 594 FLEALNMQRKS 604 Score = 35.8 bits (81), Expect = 0.17 Identities = 20/77 (25%), Positives = 36/77 (46%) Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 +L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L + Sbjct: 365 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 424 Query: 676 GVVQHALKKSEKALDTL 692 V +A +TL Sbjct: 425 AVSFTNESLQRQACETL 441 Score = 30.4 bits (67), Expect = 7.0 Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%) Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 +L + D EAW G + + +AI +R +++ P+ A L F Sbjct: 371 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 430 Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657 +A R+ +R P + + A G LG + + E+ Sbjct: 431 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 489 Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715 F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L Sbjct: 490 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 549 Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770 + + A+ ++ P + +G LG A+ +F A+++ P+G Sbjct: 550 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 609 Query: 771 ANNQIKEAI 779 + E I Sbjct: 610 EGGAMSENI 618 >gi|21361204 peroxisomal biogenesis factor 5 isoform b [Homo sapiens] Length = 631 Score = 55.5 bits (132), Expect = 2e-07 Identities = 36/131 (27%), Positives = 64/131 (48%), Gaps = 3/131 (2%) Query: 538 IYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597 + S +L+ K++ L+ + D T +D P+ C G F+L E+D A+ F A+ V Sbjct: 454 LLSDSLFLEVKELFLAAVRLDPTSID---PDVQCGLGVLFNLSGEYDKAVDCFTAALSVR 510 Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657 PN + LG + ++A+A +R A+ + P + + Y LG+ A H Sbjct: 511 PNDYLLWNKLGATLANGNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEH 570 Query: 658 FQKALDINPQS 668 F +AL++ +S Sbjct: 571 FLEALNMQRKS 581 Score = 35.8 bits (81), Expect = 0.17 Identities = 20/77 (25%), Positives = 36/77 (46%) Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 +L A+ F A++ +P+H AW LG + E+ LA ++ L++ P + L + Sbjct: 342 DLPNAVLLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMAL 401 Query: 676 GVVQHALKKSEKALDTL 692 V +A +TL Sbjct: 402 AVSFTNESLQRQACETL 418 Score = 30.4 bits (67), Expect = 7.0 Identities = 48/249 (19%), Positives = 94/249 (37%), Gaps = 24/249 (9%) Query: 554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 +L + D EAW G + + +AI +R +++ P+ A L F Sbjct: 348 LLFEAAVQQDPKHMEAWQYLGTTQAENEQELLAISALRRCLELKPDNQTALMALAVSFTN 407 Query: 614 TEELDKALACFRNAIRVNPRHYN-----------AWYG-----LGMIYYKQEKFSLAEMH 657 +A R+ +R P + + A G LG + + E+ Sbjct: 408 ESLQRQACETLRDWLRYTPAYAHLVTPAEEGAGGAGLGPSKRILGSLLSDSLFLEVKEL- 466 Query: 658 FQKALDINPQS--SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715 F A+ ++P S + C +GV+ + + +KA+D A+ + P + L + L Sbjct: 467 FLAAVRLDPTSIDPDVQCGLGVLFNLSGEYDKAVDCFTAALSVRPNDYLLWNKLGATLAN 526 Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD-----PKG 770 + + A+ ++ P + +G LG A+ +F A+++ P+G Sbjct: 527 GNQSEEAVAAYRRALELQPGYIRSRYNLGISCINLGAHREAVEHFLEALNMQRKSRGPRG 586 Query: 771 ANNQIKEAI 779 + E I Sbjct: 587 EGGAMSENI 595 >gi|224809432 transmembrane and tetratricopeptide repeat containing 3 [Homo sapiens] Length = 914 Score = 55.5 bits (132), Expect = 2e-07 Identities = 41/156 (26%), Positives = 77/156 (49%), Gaps = 4/156 (2%) Query: 593 AIQVDPNYAYAYTLLGHEFVLTEE-LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKF 651 A ++ PN+ Y L + E L++A +R AI + P A+ G + K K Sbjct: 520 AARIAPNHLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKP 579 Query: 652 SLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRAS 711 A+ + KAL+++ ++ L ++ +V LK+ +AL N+A+ ++PK+ L F+ A Sbjct: 580 LKAKEAYLKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAI 639 Query: 712 VLFANEKYKSALQELEELKQIVPKESL---VYFLIG 744 V+ + + K + + L + +E L YF +G Sbjct: 640 VMQESGEVKLRPEARKRLLSYINEEPLDANGYFNLG 675 Score = 53.9 bits (128), Expect = 6e-07 Identities = 57/275 (20%), Positives = 115/275 (41%), Gaps = 28/275 (10%) Query: 544 WHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYA 603 W + + +S L ++KN+ + W G+ ++ + A+K+F +A V P+ A Sbjct: 428 WESEYTLFMSALK-----VNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQPDDIGA 482 Query: 604 YTLLGHEFV---LTEELDKALACFRN-----------AIRVNPRHYNAWYGL-GMIYYKQ 648 + +G + T+E +++ ++ A R+ P H N + L +I + Sbjct: 483 HMNVGRTYKNLNRTKEAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYINLANLIRANE 542 Query: 649 EKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFH 708 + A+ +++A+ + P G + + K KA + KA+ +D N ++ Sbjct: 543 SRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYN 602 Query: 709 RASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHL------ALMNFSW 762 A V ++ AL+ ++ PK L F V ++ G+ L L+++ Sbjct: 603 LAIVHIELKEPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYIN 662 Query: 763 AMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQI 797 LD G N A+D + D+E I ++ I Sbjct: 663 EEPLDANGYFNLGMLAMDDK--KDNEAEIWMKKAI 695 Score = 42.0 bits (97), Expect = 0.002 Identities = 32/141 (22%), Positives = 64/141 (45%), Gaps = 7/141 (4%) Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD-- 618 ++D+N+ + W +E + A+K F RA++++P + A L V+ E + Sbjct: 591 ELDRNNADLWYNLAIVHIELKEPNEALKNFNRALELNPKHKLA--LFNSAIVMQESGEVK 648 Query: 619 ---KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 +A + I P N ++ LGM+ +K + AE+ +KA+ + L ++ Sbjct: 649 LRPEARKRLLSYINEEPLDANGYFNLGMLAMDDKKDNEAEIWMKKAIKLQADFRSALFNL 708 Query: 676 GVVQHALKKSEKALDTLNKAI 696 ++ K KAL L + + Sbjct: 709 ALLYSQTAKELKALPILEELL 729 Score = 40.4 bits (93), Expect = 0.007 Identities = 44/227 (19%), Positives = 86/227 (37%), Gaps = 38/227 (16%) Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645 A + +++AI + P++ AY G + + KA + A+ ++ + + WY L +++ Sbjct: 548 ADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLWYNLAIVH 607 Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHAL----------------------- 682 + ++ + A +F +AL++NP+ + L + +V Sbjct: 608 IELKEPNEALKNFNRALELNPKHKLALFNSAIVMQESGEVKLRPEARKRLLSYINEEPLD 667 Query: 683 --------------KKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728 KK +A + KAI + F+ A + K AL LEE Sbjct: 668 ANGYFNLGMLAMDDKKDNEAEIWMKKAIKLQADFRSALFNLALLYSQTAKELKALPILEE 727 Query: 729 LKQIVPKESLVYFLIGKVYKKLGQTHL-ALMNFSWAMDLDPKGANNQ 774 L + P L G + + L A F +++DP + Sbjct: 728 LLRYYPDHIKGLILKGDILMNQKKDILGAKKCFERILEMDPSNVQGK 774 Score = 32.3 bits (72), Expect = 1.8 Identities = 18/102 (17%), Positives = 47/102 (46%), Gaps = 3/102 (2%) Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD--KALACFRNAIRVNPRHYNAWYGLGM 643 A+ + ++ P++ L G + ++ ++ D A CF + ++P + + L + Sbjct: 721 ALPILEELLRYYPDHIKGLILKG-DILMNQKKDILGAKKCFERILEMDPSNVQGKHNLCV 779 Query: 644 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKS 685 +Y++++ AE + L + P + H+ +V+ + S Sbjct: 780 VYFEEKDLLKAERCLLETLALAPHEEYIQRHLNIVRDKISSS 821 >gi|212549738 anaphase-promoting complex subunit 7 isoform b [Homo sapiens] Length = 537 Score = 55.1 bits (131), Expect = 3e-07 Identities = 50/226 (22%), Positives = 92/226 (40%), Gaps = 5/226 (2%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 +L + YF + + F + + ++ Y ++GM++Y L + + L L Sbjct: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332 Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620 ++ E W +G + + A+ +AIQ++ N A L G + +A Sbjct: 333 NISDQHAEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEA 392 Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIGV 677 + FR AIR+ P + + GL Y A + + K L N Q+ LL + + Sbjct: 393 IIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCL 452 Query: 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSAL 723 + EKA L+KA+ P +A +L +KY+ + Sbjct: 453 EDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGI 496 >gi|170784867 tetratricopeptide repeat domain 13 isoform a [Homo sapiens] Length = 860 Score = 54.3 bits (129), Expect = 5e-07 Identities = 57/251 (22%), Positives = 104/251 (41%), Gaps = 18/251 (7%) Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFE--LSEYMQAERIFSEV 525 E+ Y+ + S EAI S + + + G AY + L + AE E+ Sbjct: 146 ELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFEL 205 Query: 526 RRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEA--WCAAGNCFSLQREH 583 R+ + E++ L ++ DLT + P A + G + + ++ Sbjct: 206 SRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDY 265 Query: 584 DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGM 643 A + FQ++++++ N A G F L +A+ F+ A++ +A+ LG Sbjct: 266 ATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQ 325 Query: 644 IYYKQEKFSLAEMHFQKALDINPQ-------SSVLLCHIGVVQHALKKSEKALDTLNKAI 696 Y + F A FQKAL +N ++L H G +Q ALK ++ L Sbjct: 326 AYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQ------ 379 Query: 697 VIDPKNPLCKF 707 ++P N +C++ Sbjct: 380 -LEPYNEVCQY 389 Score = 45.8 bits (107), Expect = 2e-04 Identities = 47/236 (19%), Positives = 99/236 (41%), Gaps = 2/236 (0%) Query: 549 DVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG 608 ++AL LS+ +T ++ + PE + S + A+ +AIQ+ P+ A Y G Sbjct: 199 ELALFELSRVIT-LEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPS-ARLYRHRG 256 Query: 609 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 668 + ++E+ A F+ ++ +N A G+ ++ + A F++AL Sbjct: 257 TLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDF 316 Query: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728 +G L E A ++ KA++++ + R +L+ + + AL+ + Sbjct: 317 IDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKR 376 Query: 729 LKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYL 784 Q+ P + ++ G + +GQ + + + M DP E + +YL Sbjct: 377 CLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKYL 432 >gi|170784869 tetratricopeptide repeat domain 13 isoform b [Homo sapiens] Length = 807 Score = 53.5 bits (127), Expect = 8e-07 Identities = 45/183 (24%), Positives = 81/183 (44%), Gaps = 16/183 (8%) Query: 534 EGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEA--WCAAGNCFSLQREHDIAIKFFQ 591 E + +ST L L ++ DLT + P A + G + + ++ A + FQ Sbjct: 161 EAIRHFSTMLQILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQ 220 Query: 592 RAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKF 651 ++++++ N A G F L +A+ F+ A++ +A+ LG Y + F Sbjct: 221 QSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNF 280 Query: 652 SLAEMHFQKALDINPQ-------SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704 A FQKAL +N ++L H G +Q ALK ++ L ++P N + Sbjct: 281 EAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQ-------LEPYNEV 333 Query: 705 CKF 707 C++ Sbjct: 334 CQY 336 Score = 42.0 bits (97), Expect = 0.002 Identities = 39/199 (19%), Positives = 82/199 (41%), Gaps = 1/199 (0%) Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645 A+ +AIQ+ P+ A Y G + ++E+ A F+ ++ +N A G+ + Sbjct: 182 AVNDLTKAIQLQPS-ARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTF 240 Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705 + + A F++AL +G L E A ++ KA++++ + Sbjct: 241 FHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQT 300 Query: 706 KFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMD 765 R +L+ + + AL+ + Q+ P + ++ G + +GQ + + + M Sbjct: 301 LQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVML 360 Query: 766 LDPKGANNQIKEAIDKRYL 784 DP E + +YL Sbjct: 361 NDPLPGQKASPEYLKVKYL 379 >gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo sapiens] Length = 515 Score = 52.0 bits (123), Expect = 2e-06 Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 5/170 (2%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGME-IYSTTLWHLQKDVALSVLSKDL 559 +LC I R Y E++ A + EV + +N VE + I S + Q ++AL + L Sbjct: 294 LLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRR-L 352 Query: 560 TDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL---LGHEFVLTEE 616 M + + + G C +++D+ + F+RA+ + N A + LGH V + Sbjct: 353 LQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGD 412 Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666 + A CFR A+ N H A+ L ++ ++ A Q A + P Sbjct: 413 TNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 462 Score = 46.2 bits (108), Expect = 1e-04 Identities = 33/184 (17%), Positives = 74/184 (40%), Gaps = 2/184 (1%) Query: 482 KEAINILSHLPSH-HYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 K A+++ + H Y W QIG+ Y+ L Y +AE+ F + + V+ + Sbjct: 207 KTALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLA 265 Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 L + V L K D C + A ++++ ++ D + Sbjct: 266 KVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTH 325 Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 A +G +++ + AL +R +++ + + LG+ + +++ + F++ Sbjct: 326 VEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFER 385 Query: 661 ALDI 664 AL + Sbjct: 386 ALSL 389 >gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo sapiens] Length = 475 Score = 52.0 bits (123), Expect = 2e-06 Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 5/170 (2%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGME-IYSTTLWHLQKDVALSVLSKDL 559 +LC I R Y E++ A + EV + +N VE + I S + Q ++AL + L Sbjct: 254 LLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRR-L 312 Query: 560 TDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL---LGHEFVLTEE 616 M + + + G C +++D+ + F+RA+ + N A + LGH V + Sbjct: 313 LQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGD 372 Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666 + A CFR A+ N H A+ L ++ ++ A Q A + P Sbjct: 373 TNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 422 Score = 46.2 bits (108), Expect = 1e-04 Identities = 33/184 (17%), Positives = 74/184 (40%), Gaps = 2/184 (1%) Query: 482 KEAINILSHLPSH-HYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 K A+++ + H Y W QIG+ Y+ L Y +AE+ F + + V+ + Sbjct: 167 KTALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLA 225 Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 L + V L K D C + A ++++ ++ D + Sbjct: 226 KVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTH 285 Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 A +G +++ + AL +R +++ + + LG+ + +++ + F++ Sbjct: 286 VEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFER 345 Query: 661 ALDI 664 AL + Sbjct: 346 ALSL 349 >gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo sapiens] Length = 505 Score = 52.0 bits (123), Expect = 2e-06 Identities = 44/170 (25%), Positives = 76/170 (44%), Gaps = 5/170 (2%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGME-IYSTTLWHLQKDVALSVLSKDL 559 +LC I R Y E++ A + EV + +N VE + I S + Q ++AL + L Sbjct: 284 LLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRR-L 342 Query: 560 TDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL---LGHEFVLTEE 616 M + + + G C +++D+ + F+RA+ + N A + LGH V + Sbjct: 343 LQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGD 402 Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666 + A CFR A+ N H A+ L ++ ++ A Q A + P Sbjct: 403 TNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQARALLQTASSLAP 452 Score = 46.2 bits (108), Expect = 1e-04 Identities = 33/184 (17%), Positives = 74/184 (40%), Gaps = 2/184 (1%) Query: 482 KEAINILSHLPSH-HYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 K A+++ + H Y W QIG+ Y+ L Y +AE+ F + + V+ + Sbjct: 197 KTALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLA 255 Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 L + V L K D C + A ++++ ++ D + Sbjct: 256 KVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTH 315 Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 A +G +++ + AL +R +++ + + LG+ + +++ + F++ Sbjct: 316 VEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFER 375 Query: 661 ALDI 664 AL + Sbjct: 376 ALSL 379 >gi|54607135 translocase of outer mitochondrial membrane 70 homolog A [Homo sapiens] Length = 608 Score = 52.0 bits (123), Expect = 2e-06 Identities = 56/254 (22%), Positives = 113/254 (44%), Gaps = 27/254 (10%) Query: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640 +E D K+ A+ + + Y L+G+ +LDK ++ +++ NA Sbjct: 319 KEIDAEGKYMAEALLLRATF---YLLIGNANAAKPDLDKVISLKEANVKLRA---NALIK 372 Query: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700 G +Y +Q++ L+ F A DI+PQ++ + H G ++ L + E+A+ ++ I + P Sbjct: 373 RGSMYMQQQQPLLSTQDFNMAADIDPQNADVYHHRGQLKILLDQVEEAVADFDECIRLRP 432 Query: 701 KNPLCKFHRASVLFA-------NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753 ++ L + + L+ + + ++A++ EE+ + P+ + Y L + Q Sbjct: 433 ESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQF 492 Query: 754 HLALMNFSWAMDLDPKGANNQIKEAI----DKRYLPDDEEPITQEEQI----------MG 799 A + +DL+P A + + + K+ L E I++ +I MG Sbjct: 493 GKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMG 552 Query: 800 TDESQESSMTDADD 813 T E Q +M A D Sbjct: 553 TIEVQRGNMEKAID 566 Score = 40.0 bits (92), Expect = 0.009 Identities = 39/165 (23%), Positives = 67/165 (40%), Gaps = 16/165 (9%) Query: 547 QKDVALSVLSKDLTDMDK----NSPEAWCAAGNCFSLQREH---------DIAIKFFQRA 593 Q + L + + + D D+ A A CF+L R+ A+K F+ Sbjct: 409 QLKILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQAAMKGFEEV 468 Query: 594 IQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWY--GLGMIYYKQEKF 651 I+ P A Y L ++ KA + I + P + + GL + +KQ+ Sbjct: 469 IKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLD 528 Query: 652 SLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696 E+ KA++I+ + +G ++ EKA+D NKAI Sbjct: 529 RGLEL-ISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAI 572 Score = 32.3 bits (72), Expect = 1.8 Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 3/120 (2%) Query: 513 SEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCA 572 S+ A + F EV + EG +Y+ L Q+ + D++ ++ + Sbjct: 456 SQIQAAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVH 515 Query: 573 AGNCFSLQREHDI--AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV 630 G LQ + D+ ++ +AI++D +AY +G V ++KA+ F AI + Sbjct: 516 KG-LLQLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINL 574 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.130 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,917,031 Number of Sequences: 37866 Number of extensions: 1521477 Number of successful extensions: 7049 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 198 Number of HSP's that attempted gapping in prelim test: 5691 Number of HSP's gapped (non-prelim): 1048 length of query: 824 length of database: 18,247,518 effective HSP length: 111 effective length of query: 713 effective length of database: 14,044,392 effective search space: 10013651496 effective search space used: 10013651496 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.