Guide to the Human Genome
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Search of human proteins with 166851840

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166851840 E74-like factor 3 (ets domain transcription
factor, epithelial-specific ) [Homo sapiens]
         (371 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166851840 E74-like factor 3 (ets domain transcription factor,...   767   0.0  
gi|167235023 E74-like factor 3 (ets domain transcription factor,...   767   0.0  
gi|27436883 ets homologous factor [Homo sapiens]                      179   5e-45
gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]                   141   1e-33
gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]                    141   1e-33
gi|27363484 E74-like factor 1 (ets domain transcription factor) ...    92   7e-19
gi|223941929 E74-like factor 1 (ets domain transcription factor)...    92   7e-19
gi|42544172 E74-like factor 2 (ets domain transcription factor) ...    91   2e-18
gi|6857816 E74-like factor 2 (ets domain transcription factor) i...    91   2e-18
gi|187608767 E74-like factor 4 [Homo sapiens]                          89   8e-18
gi|4503555 E74-like factor 4 [Homo sapiens]                            89   8e-18
gi|11496882 ELK4 protein isoform b [Homo sapiens]                      82   6e-16
gi|41872448 ELK4 protein isoform a [Homo sapiens]                      82   6e-16
gi|166362732 ELK1 protein [Homo sapiens]                               82   8e-16
gi|166362730 ELK1 protein [Homo sapiens]                               82   8e-16
gi|44955921 ELK3 protein [Homo sapiens]                                82   1e-15
gi|6912580 SAM pointed domain containing ets transcription facto...    80   2e-15
gi|8923789 FEV (ETS oncogene family) [Homo sapiens]                    77   2e-14
gi|4503611 ets variant 6 [Homo sapiens]                                76   6e-14
gi|4758300 ets-related isoform 2 [Homo sapiens]                        75   1e-13
gi|34452721 GA binding protein transcription factor, alpha subun...    74   2e-13
gi|7706731 ets variant 7 [Homo sapiens]                                74   2e-13
gi|223718207 ets variant gene 3 isoform 1 [Homo sapiens]               74   2e-13
gi|20270188 ets variant gene 3 isoform 2 [Homo sapiens]                74   2e-13
gi|209954808 ets-related isoform 4 [Homo sapiens]                      74   3e-13
gi|33667107 ets-related isoform 1 [Homo sapiens]                       74   3e-13
gi|209954797 ets-related isoform 3 [Homo sapiens]                      74   3e-13
gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]          74   3e-13
gi|51972258 ets variant 3-like [Homo sapiens]                          73   5e-13
gi|156104872 Ets2 repressor factor [Homo sapiens]                      72   6e-13

>gi|166851840 E74-like factor 3 (ets domain transcription factor,
           epithelial-specific ) [Homo sapiens]
          Length = 371

 Score =  767 bits (1980), Expect = 0.0
 Identities = 371/371 (100%), Positives = 371/371 (100%)

Query: 1   MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWL 60
           MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWL
Sbjct: 1   MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWL 60

Query: 61  GEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQ 120
           GEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQ
Sbjct: 61  GEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQ 120

Query: 121 LHAQLRDLTSSSSDELSWIIELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYH 180
           LHAQLRDLTSSSSDELSWIIELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYH
Sbjct: 121 LHAQLRDLTSSSSDELSWIIELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYH 180

Query: 181 PGSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDP 240
           PGSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDP
Sbjct: 181 PGSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDP 240

Query: 241 KHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHE 300
           KHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHE
Sbjct: 241 KHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHE 300

Query: 301 GVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSG 360
           GVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSG
Sbjct: 301 GVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSG 360

Query: 361 WKEEEVLQSRN 371
           WKEEEVLQSRN
Sbjct: 361 WKEEEVLQSRN 371


>gi|167235023 E74-like factor 3 (ets domain transcription factor,
           epithelial-specific ) [Homo sapiens]
          Length = 371

 Score =  767 bits (1980), Expect = 0.0
 Identities = 371/371 (100%), Positives = 371/371 (100%)

Query: 1   MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWL 60
           MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWL
Sbjct: 1   MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWL 60

Query: 61  GEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQ 120
           GEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQ
Sbjct: 61  GEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQ 120

Query: 121 LHAQLRDLTSSSSDELSWIIELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYH 180
           LHAQLRDLTSSSSDELSWIIELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYH
Sbjct: 121 LHAQLRDLTSSSSDELSWIIELLEKDGMAFQEALDPGPFDQGSPFAQELLDDGQQASPYH 180

Query: 181 PGSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDP 240
           PGSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDP
Sbjct: 181 PGSCGAGAPSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDP 240

Query: 241 KHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHE 300
           KHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHE
Sbjct: 241 KHGKRKRGRPRKLSKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHE 300

Query: 301 GVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSG 360
           GVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSG
Sbjct: 301 GVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSG 360

Query: 361 WKEEEVLQSRN 371
           WKEEEVLQSRN
Sbjct: 361 WKEEEVLQSRN 371


>gi|27436883 ets homologous factor [Homo sapiens]
          Length = 300

 Score =  179 bits (453), Expect = 5e-45
 Identities = 81/99 (81%), Positives = 92/99 (92%)

Query: 267 KHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTY 326
           KH PRGTHLWEFIRDIL++P+ N GL+KWE+R EGVF+FL+SEAVAQLWG+KK NS+MTY
Sbjct: 201 KHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTY 260

Query: 327 EKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEE 365
           EKLSRAMRYYYKREILERVDGRRLVYKFGKN+ GW+E E
Sbjct: 261 EKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENE 299



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 24/70 (34%), Positives = 41/70 (58%)

Query: 59  WLGEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLG 118
           W    PQ+W+K QV +W+ + ++ N+ DA+ I F   D++G  LC+ +L+E     G  G
Sbjct: 42  WHEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAG 101

Query: 119 DQLHAQLRDL 128
             L++ L+ L
Sbjct: 102 QLLYSNLQHL 111


>gi|38201717 E74-like factor 5 ESE-2a [Homo sapiens]
          Length = 265

 Score =  141 bits (355), Expect = 1e-33
 Identities = 61/101 (60%), Positives = 87/101 (86%), Gaps = 1/101 (0%)

Query: 266 SKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMT 325
           S+ + + +HLWEF+RD+L+ PE N G+++WE+R +G+F+ ++SEA+A++WGQ+KKN  MT
Sbjct: 166 SRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMT 225

Query: 326 YEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEV 366
           YEKLSRA+RYYYK  ILERVD RRLVYKFGKN+ GW+E+++
Sbjct: 226 YEKLSRALRYYYKTGILERVD-RRLVYKFGKNAHGWQEDKL 265



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 19/70 (27%), Positives = 36/70 (51%)

Query: 59  WLGEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLG 118
           W    P++W+K  V +W+ +  ++ K D + I F   ++ G  LC+   EE     G  G
Sbjct: 56  WTSVHPEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCG 115

Query: 119 DQLHAQLRDL 128
           + L+  L+++
Sbjct: 116 EYLYFILQNI 125


>gi|4557551 E74-like factor 5 ESE-2b [Homo sapiens]
          Length = 255

 Score =  141 bits (355), Expect = 1e-33
 Identities = 61/101 (60%), Positives = 87/101 (86%), Gaps = 1/101 (0%)

Query: 266 SKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMT 325
           S+ + + +HLWEF+RD+L+ PE N G+++WE+R +G+F+ ++SEA+A++WGQ+KKN  MT
Sbjct: 156 SRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMT 215

Query: 326 YEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEV 366
           YEKLSRA+RYYYK  ILERVD RRLVYKFGKN+ GW+E+++
Sbjct: 216 YEKLSRALRYYYKTGILERVD-RRLVYKFGKNAHGWQEDKL 255



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 19/70 (27%), Positives = 36/70 (51%)

Query: 59  WLGEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLG 118
           W    P++W+K  V +W+ +  ++ K D + I F   ++ G  LC+   EE     G  G
Sbjct: 46  WTSVHPEYWTKRHVWEWLQFCCDQYKLDTNCISFCNFNISGLQLCSMTQEEFVEAAGLCG 105

Query: 119 DQLHAQLRDL 128
           + L+  L+++
Sbjct: 106 EYLYFILQNI 115


>gi|27363484 E74-like factor 1 (ets domain transcription factor)
           isoform a [Homo sapiens]
          Length = 619

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 6/121 (4%)

Query: 240 PKHGKRKRGR----PRKLSKEYWDCLEGKKSKHAPRGT--HLWEFIRDILIHPELNEGLM 293
           P+  KRK+GR    PR  S      +  KK     +G   +LWEF+  +L         +
Sbjct: 169 PEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYI 228

Query: 294 KWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYK 353
           KW  R +G+FK + S+AV++LWG+ K   +M YE + RA+RYYY+R IL +V+G+RLVY+
Sbjct: 229 KWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQ 288

Query: 354 F 354
           F
Sbjct: 289 F 289


>gi|223941929 E74-like factor 1 (ets domain transcription factor)
           isoform b [Homo sapiens]
          Length = 595

 Score = 92.0 bits (227), Expect = 7e-19
 Identities = 49/121 (40%), Positives = 72/121 (59%), Gaps = 6/121 (4%)

Query: 240 PKHGKRKRGR----PRKLSKEYWDCLEGKKSKHAPRGT--HLWEFIRDILIHPELNEGLM 293
           P+  KRK+GR    PR  S      +  KK     +G   +LWEF+  +L         +
Sbjct: 145 PEQPKRKKGRKTKPPRPDSPATTPNISVKKKNKDGKGNTIYLWEFLLALLQDKATCPKYI 204

Query: 294 KWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYK 353
           KW  R +G+FK + S+AV++LWG+ K   +M YE + RA+RYYY+R IL +V+G+RLVY+
Sbjct: 205 KWTQREKGIFKLVDSKAVSRLWGKHKNKPDMNYETMGRALRYYYQRGILAKVEGQRLVYQ 264

Query: 354 F 354
           F
Sbjct: 265 F 265


>gi|42544172 E74-like factor 2 (ets domain transcription factor)
           isoform 1 [Homo sapiens]
          Length = 581

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 42/93 (45%), Positives = 62/93 (66%), Gaps = 2/93 (2%)

Query: 264 KKSKHAPRG--THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKN 321
           KK     +G  T+LWEF+ D+L         +KW  R +G+FK + S+AV++LWG+ K  
Sbjct: 185 KKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNK 244

Query: 322 SNMTYEKLSRAMRYYYKREILERVDGRRLVYKF 354
            +M YE + RA+RYYY+R IL +V+G+RLVY+F
Sbjct: 245 PDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 277


>gi|6857816 E74-like factor 2 (ets domain transcription factor)
           isoform 2 [Homo sapiens]
          Length = 533

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 42/93 (45%), Positives = 62/93 (66%), Gaps = 2/93 (2%)

Query: 264 KKSKHAPRG--THLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKN 321
           KK     +G  T+LWEF+ D+L         +KW  R +G+FK + S+AV++LWG+ K  
Sbjct: 137 KKKPREGKGNTTYLWEFLLDLLQDKNTCPRYIKWTQREKGIFKLVDSKAVSKLWGKHKNK 196

Query: 322 SNMTYEKLSRAMRYYYKREILERVDGRRLVYKF 354
            +M YE + RA+RYYY+R IL +V+G+RLVY+F
Sbjct: 197 PDMNYETMGRALRYYYQRGILAKVEGQRLVYQF 229


>gi|187608767 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 42/92 (45%), Positives = 62/92 (67%), Gaps = 1/92 (1%)

Query: 264 KKSKHAPRGT-HLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNS 322
           KKSK     T +LWEF+  +L         +KW  R +G+FK + S+AV++LWG++K   
Sbjct: 199 KKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKP 258

Query: 323 NMTYEKLSRAMRYYYKREILERVDGRRLVYKF 354
           +M YE + RA+RYYY+R IL +V+G+RLVY+F
Sbjct: 259 DMNYETMGRALRYYYQRGILAKVEGQRLVYQF 290


>gi|4503555 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 88.6 bits (218), Expect = 8e-18
 Identities = 42/92 (45%), Positives = 62/92 (67%), Gaps = 1/92 (1%)

Query: 264 KKSKHAPRGT-HLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNS 322
           KKSK     T +LWEF+  +L         +KW  R +G+FK + S+AV++LWG++K   
Sbjct: 199 KKSKDGKGSTIYLWEFLLALLQDRNTCPKYIKWTQREKGIFKLVDSKAVSKLWGKQKNKP 258

Query: 323 NMTYEKLSRAMRYYYKREILERVDGRRLVYKF 354
           +M YE + RA+RYYY+R IL +V+G+RLVY+F
Sbjct: 259 DMNYETMGRALRYYYQRGILAKVEGQRLVYQF 290


>gi|11496882 ELK4 protein isoform b [Homo sapiens]
          Length = 405

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 37/80 (46%), Positives = 60/80 (75%), Gaps = 2/80 (2%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+  +L  P+ N+ ++ W + ++G FK L++E VA+LWG +K   NM Y+KLSRA+R
Sbjct: 7   LWQFLLQLLQKPQ-NKHMICWTS-NDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALR 64

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+++V+G++ VYKF
Sbjct: 65  YYYVKNIIKKVNGQKFVYKF 84


>gi|41872448 ELK4 protein isoform a [Homo sapiens]
          Length = 431

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 37/80 (46%), Positives = 60/80 (75%), Gaps = 2/80 (2%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+  +L  P+ N+ ++ W + ++G FK L++E VA+LWG +K   NM Y+KLSRA+R
Sbjct: 7   LWQFLLQLLQKPQ-NKHMICWTS-NDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRALR 64

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+++V+G++ VYKF
Sbjct: 65  YYYVKNIIKKVNGQKFVYKF 84


>gi|166362732 ELK1 protein [Homo sapiens]
          Length = 428

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 36/80 (45%), Positives = 55/80 (68%), Gaps = 1/80 (1%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+  +L   + N  ++ W +R  G FK + +E VA+LWG +K  +NM Y+KLSRA+R
Sbjct: 7   LWQFLLQLL-REQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALR 65

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+ +V G++ VYKF
Sbjct: 66  YYYDKNIIRKVSGQKFVYKF 85


>gi|166362730 ELK1 protein [Homo sapiens]
          Length = 428

 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 36/80 (45%), Positives = 55/80 (68%), Gaps = 1/80 (1%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+  +L   + N  ++ W +R  G FK + +E VA+LWG +K  +NM Y+KLSRA+R
Sbjct: 7   LWQFLLQLL-REQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALR 65

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+ +V G++ VYKF
Sbjct: 66  YYYDKNIIRKVSGQKFVYKF 85


>gi|44955921 ELK3 protein [Homo sapiens]
          Length = 407

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 37/80 (46%), Positives = 60/80 (75%), Gaps = 2/80 (2%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+  +L+  + +E L+ W + ++G FK L++E VA+LWG +K  +NM Y+KLSRA+R
Sbjct: 7   LWQFLLQLLLDQK-HEHLICWTS-NDGEFKLLKAEEVAKLWGLRKNKTNMNYDKLSRALR 64

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+++V G++ VYKF
Sbjct: 65  YYYDKNIIKKVIGQKFVYKF 84


>gi|6912580 SAM pointed domain containing ets transcription factor
           [Homo sapiens]
          Length = 335

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 40/102 (39%), Positives = 64/102 (62%), Gaps = 2/102 (1%)

Query: 254 SKEYWDCLEGKKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQ 313
           S+E W   E   S  + +  HLW+F++++L+ P      ++W N+ +G+FK   S  VA+
Sbjct: 231 SEESWTDSE-VDSSCSGQPIHLWQFLKELLLKPHSYGRFIRWLNKEKGIFKIEDSAQVAR 289

Query: 314 LWGQKKKNSNMTYEKLSRAMRYYYKREILERVD-GRRLVYKF 354
           LWG +K    M Y+KLSR++R YYK+ I+ + D  +RLVY+F
Sbjct: 290 LWGIRKNRPAMNYDKLSRSIRQYYKKGIIRKPDISQRLVYQF 331


>gi|8923789 FEV (ETS oncogene family) [Homo sapiens]
          Length = 238

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 35/80 (43%), Positives = 51/80 (63%), Gaps = 2/80 (2%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+ ++L     N G + WE  H G FK    + VA+ WG++K   NM Y+KLSRA+R
Sbjct: 49  LWQFLLELLAD-RANAGCIAWEGGH-GEFKLTDPDEVARRWGERKSKPNMNYDKLSRALR 106

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+ +V G+R  Y+F
Sbjct: 107 YYYDKNIMSKVHGKRYAYRF 126


>gi|4503611 ets variant 6 [Homo sapiens]
          Length = 452

 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 31/82 (37%), Positives = 54/82 (65%), Gaps = 1/82 (1%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+++  +L      E  ++WE++   +F+ +    +A+LWG  K  +NMTYEK+SRA+R
Sbjct: 341 LWDYVYQLLSDSRY-ENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALR 399

Query: 335 YYYKREILERVDGRRLVYKFGK 356
           +YYK  I+ +  G+RL+++F K
Sbjct: 400 HYYKLNIIRKEPGQRLLFRFMK 421



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 63  QPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQLH 122
           QP +WS+  V  W+ +   +N++    ID +  +M+G  L     E+ R      GD L+
Sbjct: 57  QPIYWSRDDVAQWLKW--AENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLY 114

Query: 123 AQLRDL 128
             L+ +
Sbjct: 115 ELLQHI 120


>gi|4758300 ets-related isoform 2 [Homo sapiens]
          Length = 462

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 50/171 (29%), Positives = 80/171 (46%), Gaps = 10/171 (5%)

Query: 189 PSPGSSDVSTAGTGASRSSHSSDSGGSDVDLDPTDGKLFPSDGFR--DCKKGDPKHGKRK 246
           P   S DV  A   + R  H+ ++   D+  +P     +   G      K   P      
Sbjct: 208 PHLTSDDVDKALQNSPRLMHARNT---DLPYEPPRRSAWTGHGHPTPQSKAAQPSPSTVP 264

Query: 247 RGRPRKLSKEYWDCLEGKKSKHAPRGT---HLWEFIRDILIHPELNEGLMKWENRHEGVF 303
           +   ++   + +  L    S+ A  G+    LW+F+ ++L     N   + WE  + G F
Sbjct: 265 KTEDQRPQLDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSS-NSSCITWEGTN-GEF 322

Query: 304 KFLRSEAVAQLWGQKKKNSNMTYEKLSRAMRYYYKREILERVDGRRLVYKF 354
           K    + VA+ WG++K   NM Y+KLSRA+RYYY + I+ +V G+R  YKF
Sbjct: 323 KMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 373


>gi|34452721 GA binding protein transcription factor, alpha subunit
           [Homo sapiens]
          Length = 454

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 36/80 (45%), Positives = 51/80 (63%), Gaps = 2/80 (2%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+ ++L   +  +  + W    EG FK  + E VAQ WGQ+K    M YEKLSRA+R
Sbjct: 322 LWQFLLELLTDKDARD-CISWVG-DEGEFKLNQPELVAQKWGQRKNKPTMNYEKLSRALR 379

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY  +++ +V G+R VYKF
Sbjct: 380 YYYDGDMICKVQGKRFVYKF 399


>gi|7706731 ets variant 7 [Homo sapiens]
          Length = 341

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 31/82 (37%), Positives = 55/82 (67%), Gaps = 1/82 (1%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+++  +L+     E  +KWE++   +F+ +    +A+LWG  K   NMTYEK+SRA+R
Sbjct: 226 LWDYVYQLLLDTRY-EPYIKWEDKDAKIFRVVDPNGLARLWGNHKNRVNMTYEKMSRALR 284

Query: 335 YYYKREILERVDGRRLVYKFGK 356
           +YYK  I+++  G++L+++F K
Sbjct: 285 HYYKLNIIKKEPGQKLLFRFLK 306


>gi|223718207 ets variant gene 3 isoform 1 [Homo sapiens]
          Length = 512

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 36/93 (38%), Positives = 51/93 (54%), Gaps = 1/93 (1%)

Query: 265 KSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNM 324
           +S    R   LW FI ++L   E    ++ W+    G F     + VA+LWG++K    M
Sbjct: 27  ESSPGSRQIQLWHFILELLQKEEFRH-VIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQM 85

Query: 325 TYEKLSRAMRYYYKREILERVDGRRLVYKFGKN 357
            Y+KLSRA+RYYY + IL +  G+R  YKF  N
Sbjct: 86  NYDKLSRALRYYYNKRILHKTKGKRFTYKFNFN 118


>gi|20270188 ets variant gene 3 isoform 2 [Homo sapiens]
          Length = 143

 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 36/93 (38%), Positives = 51/93 (54%), Gaps = 1/93 (1%)

Query: 265 KSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNM 324
           +S    R   LW FI ++L   E    ++ W+    G F     + VA+LWG++K    M
Sbjct: 27  ESSPGSRQIQLWHFILELLQKEEFRH-VIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQM 85

Query: 325 TYEKLSRAMRYYYKREILERVDGRRLVYKFGKN 357
            Y+KLSRA+RYYY + IL +  G+R  YKF  N
Sbjct: 86  NYDKLSRALRYYYNKRILHKTKGKRFTYKFNFN 118


>gi|209954808 ets-related isoform 4 [Homo sapiens]
          Length = 387

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 34/80 (42%), Positives = 50/80 (62%), Gaps = 2/80 (2%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+ ++L     N   + WE  + G FK    + VA+ WG++K   NM Y+KLSRA+R
Sbjct: 221 LWQFLLELLSDSS-NSSCITWEGTN-GEFKMTDPDEVARRWGERKSKPNMNYDKLSRALR 278

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+ +V G+R  YKF
Sbjct: 279 YYYDKNIMTKVHGKRYAYKF 298


>gi|33667107 ets-related isoform 1 [Homo sapiens]
          Length = 479

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 34/80 (42%), Positives = 50/80 (62%), Gaps = 2/80 (2%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+ ++L     N   + WE  + G FK    + VA+ WG++K   NM Y+KLSRA+R
Sbjct: 313 LWQFLLELLSDSS-NSSCITWEGTN-GEFKMTDPDEVARRWGERKSKPNMNYDKLSRALR 370

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+ +V G+R  YKF
Sbjct: 371 YYYDKNIMTKVHGKRYAYKF 390


>gi|209954797 ets-related isoform 3 [Homo sapiens]
          Length = 486

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 34/80 (42%), Positives = 50/80 (62%), Gaps = 2/80 (2%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+ ++L     N   + WE  + G FK    + VA+ WG++K   NM Y+KLSRA+R
Sbjct: 320 LWQFLLELLSDSS-NSSCITWEGTN-GEFKMTDPDEVARRWGERKSKPNMNYDKLSRALR 377

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+ +V G+R  YKF
Sbjct: 378 YYYDKNIMTKVHGKRYAYKF 397


>gi|7110593 Friend leukemia virus integration 1 [Homo sapiens]
          Length = 452

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 34/80 (42%), Positives = 50/80 (62%), Gaps = 2/80 (2%)

Query: 275 LWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNMTYEKLSRAMR 334
           LW+F+ ++L     N   + WE  + G FK    + VA+ WG++K   NM Y+KLSRA+R
Sbjct: 283 LWQFLLELL-SDSANASCITWEGTN-GEFKMTDPDEVARRWGERKSKPNMNYDKLSRALR 340

Query: 335 YYYKREILERVDGRRLVYKF 354
           YYY + I+ +V G+R  YKF
Sbjct: 341 YYYDKNIMTKVHGKRYAYKF 360


>gi|51972258 ets variant 3-like [Homo sapiens]
          Length = 361

 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 35/90 (38%), Positives = 50/90 (55%), Gaps = 1/90 (1%)

Query: 265 KSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNM 324
           +S    R   LW FI ++L   E    ++ W+    G F     + VA+LWG++K    M
Sbjct: 31  ESSPGSRQIQLWHFILELLQKEEFRH-VIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQM 89

Query: 325 TYEKLSRAMRYYYKREILERVDGRRLVYKF 354
            Y+KLSRA+RYYY + IL +  G+R  YKF
Sbjct: 90  NYDKLSRALRYYYNKRILHKTKGKRFTYKF 119


>gi|156104872 Ets2 repressor factor [Homo sapiens]
          Length = 548

 Score = 72.4 bits (176), Expect = 6e-13
 Identities = 37/93 (39%), Positives = 53/93 (56%), Gaps = 2/93 (2%)

Query: 265 KSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSNM 324
           +S    R   LW FI ++L   E  +G++ W+  + G F     + VA+LWG +K    M
Sbjct: 19  ESSPGSRQIQLWHFILELLRKEEY-QGVIAWQGDY-GEFVIKDPDEVARLWGVRKCKPQM 76

Query: 325 TYEKLSRAMRYYYKREILERVDGRRLVYKFGKN 357
            Y+KLSRA+RYYY + IL +  G+R  YKF  N
Sbjct: 77  NYDKLSRALRYYYNKRILHKTKGKRFTYKFNFN 109


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,112,088
Number of Sequences: 37866
Number of extensions: 818836
Number of successful extensions: 2728
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 2554
Number of HSP's gapped (non-prelim): 225
length of query: 371
length of database: 18,247,518
effective HSP length: 104
effective length of query: 267
effective length of database: 14,309,454
effective search space: 3820624218
effective search space used: 3820624218
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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