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Search of human proteins with 163644267
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|163644267 neutrophil cytosolic factor 4 isoform 2 [Homo
sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|163644267 neutrophil cytosolic factor 4 isoform 2 [Homo sapiens] 709 0.0
gi|47519798 neutrophil cytosolic factor 4 isoform 1 [Homo sapiens] 508 e-144
gi|63055059 SH3 and PX domains 2B [Homo sapiens] 67 3e-11
gi|55749544 SH3 multiple domains 1 [Homo sapiens] 65 1e-10
gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens] 63 3e-10
gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens] 63 3e-10
gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens] 63 3e-10
gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens] 60 3e-09
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens] 59 6e-09
gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens] 59 8e-09
gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo ... 58 1e-08
gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo ... 58 1e-08
gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo ... 58 1e-08
gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo ... 58 1e-08
gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo ... 58 1e-08
gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo ... 58 1e-08
gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens] 58 1e-08
gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo s... 58 1e-08
gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo ... 58 1e-08
gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens] 58 1e-08
gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo s... 57 2e-08
gi|222446607 SH3 domain containing ring finger 2 [Homo sapiens] 57 3e-08
gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens] 56 5e-08
gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens] 56 5e-08
gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo ... 54 3e-07
gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo s... 54 3e-07
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 53 5e-07
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 53 5e-07
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 53 5e-07
gi|39930351 dynamin binding protein [Homo sapiens] 52 6e-07
>gi|163644267 neutrophil cytosolic factor 4 isoform 2 [Homo sapiens]
Length = 348
Score = 709 bits (1829), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MAVAQQLRAESDFEQLPDDVAISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRYR 60
MAVAQQLRAESDFEQLPDDVAISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRYR
Sbjct: 1 MAVAQQLRAESDFEQLPDDVAISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRYR 60
Query: 61 QFHALQSKLEERFGPDSKSSALACTLPTLPAKVYVGVKQEIAEMRIPALNAYMKSLLSLP 120
QFHALQSKLEERFGPDSKSSALACTLPTLPAKVYVGVKQEIAEMRIPALNAYMKSLLSLP
Sbjct: 61 QFHALQSKLEERFGPDSKSSALACTLPTLPAKVYVGVKQEIAEMRIPALNAYMKSLLSLP 120
Query: 121 VWVLMDEDVRIFFYQSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFD 180
VWVLMDEDVRIFFYQSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFD
Sbjct: 121 VWVLMDEDVRIFFYQSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFD 180
Query: 181 FTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDDPTNWL 240
FTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDDPTNWL
Sbjct: 181 FTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDDPTNWL 240
Query: 241 RCYYYEDTISTIKSVAWEGGACPAFLPSLRPLPLTSPSHGSLSHSKAPSGSQMSHNAVTS 300
RCYYYEDTISTIKSVAWEGGACPAFLPSLRPLPLTSPSHGSLSHSKAPSGSQMSHNAVTS
Sbjct: 241 RCYYYEDTISTIKSVAWEGGACPAFLPSLRPLPLTSPSHGSLSHSKAPSGSQMSHNAVTS 300
Query: 301 HQRPGWPGQPHSPFPHPTPHFQPDASLLQPVTPLGTSRWRKISAALPY 348
HQRPGWPGQPHSPFPHPTPHFQPDASLLQPVTPLGTSRWRKISAALPY
Sbjct: 301 HQRPGWPGQPHSPFPHPTPHFQPDASLLQPVTPLGTSRWRKISAALPY 348
>gi|47519798 neutrophil cytosolic factor 4 isoform 1 [Homo sapiens]
Length = 339
Score = 508 bits (1308), Expect = e-144
Identities = 255/258 (98%), Positives = 256/258 (99%)
Query: 1 MAVAQQLRAESDFEQLPDDVAISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRYR 60
MAVAQQLRAESDFEQLPDDVAISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRYR
Sbjct: 1 MAVAQQLRAESDFEQLPDDVAISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRYR 60
Query: 61 QFHALQSKLEERFGPDSKSSALACTLPTLPAKVYVGVKQEIAEMRIPALNAYMKSLLSLP 120
QFHALQSKLEERFGPDSKSSALACTLPTLPAKVYVGVKQEIAEMRIPALNAYMKSLLSLP
Sbjct: 61 QFHALQSKLEERFGPDSKSSALACTLPTLPAKVYVGVKQEIAEMRIPALNAYMKSLLSLP 120
Query: 121 VWVLMDEDVRIFFYQSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFD 180
VWVLMDEDVRIFFYQSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFD
Sbjct: 121 VWVLMDEDVRIFFYQSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFD 180
Query: 181 FTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDDPTNWL 240
FTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDDPTNWL
Sbjct: 181 FTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDDPTNWL 240
Query: 241 RCYYYEDTISTIKSVAWE 258
RCYYYEDTISTIK +A E
Sbjct: 241 RCYYYEDTISTIKDIAVE 258
>gi|63055059 SH3 and PX domains 2B [Homo sapiens]
Length = 911
Score = 66.6 bits (161), Expect = 3e-11
Identities = 45/189 (23%), Positives = 86/189 (45%), Gaps = 10/189 (5%)
Query: 22 ISANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRYRQFHALQSKLEERFGPD-SKSS 80
+ + D++++R H+V++I V GS IYRRY +F LQ ++ ++F + +
Sbjct: 8 VEVKVLDVQKRRVPNKHYVYIIRVTWSSGSTEAIYRRYSKFFDLQMQMLDKFPMEGGQKD 67
Query: 81 ALACTLPTLPAKVYVGVK--QEIAEMRIPALNAYMKSLLSLPVWVLMDEDVRIFFYQSPY 138
+P LP K+ +++A R+ ++ Y K+L+ LP ++ ++V FF P
Sbjct: 68 PKQRIIPFLPGKILFRRSHIRDVAVKRLIPIDEYCKALIQLPPYISQCDEVLQFFETRPE 127
Query: 139 DSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIF 198
D + K KS Q SVD M + + ++ E++ G V+
Sbjct: 128 DLNPPKE------EHIGKKKSGGDQ-TSVDPMVLEQYVVVANYQKQESSEISLSVGQVVD 180
Query: 199 LLSRINKDW 207
++ + W
Sbjct: 181 IIEKNESGW 189
>gi|55749544 SH3 multiple domains 1 [Homo sapiens]
Length = 1105
Score = 64.7 bits (156), Expect = 1e-10
Identities = 50/223 (22%), Positives = 98/223 (43%), Gaps = 11/223 (4%)
Query: 24 ANIADIEEKRGFTSHFVFVIEVKTKGGSKYLIYRRYRQFHALQSKLEERFGPD-SKSSAL 82
A + D+E++R + H+V++I V + IYRRY +F LQ +L ++F + +
Sbjct: 9 ATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQKDPK 68
Query: 83 ACTLPTLPAKVYVGVK--QEIAEMRIPALNAYMKSLLSLPVWVLMDEDVRIFFYQSPYD- 139
+P LP K+ +++A R+ ++ Y ++L+ LP + ++V FF P D
Sbjct: 69 QRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDV 128
Query: 140 ---SEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAEALFDFTGNSK----LELNFK 192
E + R+ + +S D A P + N K EL+ +
Sbjct: 129 NPPKEDYGSSKRKSVWLSSWAESPKKDVTGADATAEPMILEQYVVVSNYKKQENSELSLQ 188
Query: 193 AGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDD 235
AG+V+ ++ + W + G P ++++ ++ D
Sbjct: 189 AGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSD 231
>gi|193083145 SH3 domain containing 19 isoform c [Homo sapiens]
Length = 731
Score = 63.2 bits (152), Expect = 3e-10
Identities = 27/58 (46%), Positives = 40/58 (68%)
Query: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFP 231
R A F++ G K EL+F G++I L +N++W G VRG TGIFPL+FV+ ++D+P
Sbjct: 516 RCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPVEDYP 573
Score = 59.7 bits (143), Expect = 4e-09
Identities = 25/61 (40%), Positives = 37/61 (60%)
Query: 172 APRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFP 231
AP A L DF +LN +G++++LL +I+ DW G R GIFP ++VK++ D P
Sbjct: 438 APHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYVKVIIDIP 497
Query: 232 E 232
E
Sbjct: 498 E 498
Score = 59.3 bits (142), Expect = 5e-09
Identities = 24/55 (43%), Positives = 41/55 (74%)
Query: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILK 228
+A+AL+DF G ++ EL+FKAGD+I L ++ DW+ G + G +GIFP ++++ L+
Sbjct: 675 KAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQFLQ 729
Score = 52.0 bits (123), Expect = 8e-07
Identities = 26/68 (38%), Positives = 38/68 (55%)
Query: 158 KSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATG 217
K S + V+ + A EAL FT + +L+FK GD I +L R++ DW G ++ G
Sbjct: 590 KEDSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREG 649
Query: 218 IFPLSFVK 225
IFP FV+
Sbjct: 650 IFPAVFVR 657
>gi|193083143 SH3 domain containing 19 isoform b [Homo sapiens]
Length = 767
Score = 63.2 bits (152), Expect = 3e-10
Identities = 27/58 (46%), Positives = 40/58 (68%)
Query: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFP 231
R A F++ G K EL+F G++I L +N++W G VRG TGIFPL+FV+ ++D+P
Sbjct: 552 RCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPVEDYP 609
Score = 59.7 bits (143), Expect = 4e-09
Identities = 25/61 (40%), Positives = 37/61 (60%)
Query: 172 APRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFP 231
AP A L DF +LN +G++++LL +I+ DW G R GIFP ++VK++ D P
Sbjct: 474 APHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYVKVIIDIP 533
Query: 232 E 232
E
Sbjct: 534 E 534
Score = 59.3 bits (142), Expect = 5e-09
Identities = 24/55 (43%), Positives = 41/55 (74%)
Query: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILK 228
+A+AL+DF G ++ EL+FKAGD+I L ++ DW+ G + G +GIFP ++++ L+
Sbjct: 711 KAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQFLQ 765
Score = 52.0 bits (123), Expect = 8e-07
Identities = 26/68 (38%), Positives = 38/68 (55%)
Query: 158 KSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATG 217
K S + V+ + A EAL FT + +L+FK GD I +L R++ DW G ++ G
Sbjct: 626 KEDSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREG 685
Query: 218 IFPLSFVK 225
IFP FV+
Sbjct: 686 IFPAVFVR 693
>gi|193083141 SH3 domain containing 19 isoform a [Homo sapiens]
Length = 790
Score = 63.2 bits (152), Expect = 3e-10
Identities = 27/58 (46%), Positives = 40/58 (68%)
Query: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFP 231
R A F++ G K EL+F G++I L +N++W G VRG TGIFPL+FV+ ++D+P
Sbjct: 575 RCVARFEYIGEQKDELSFSEGEIIILKEYVNEEWARGEVRGRTGIFPLNFVEPVEDYP 632
Score = 59.7 bits (143), Expect = 4e-09
Identities = 25/61 (40%), Positives = 37/61 (60%)
Query: 172 APRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFP 231
AP A L DF +LN +G++++LL +I+ DW G R GIFP ++VK++ D P
Sbjct: 497 APHAVVLHDFPAEQVDDLNLTSGEIVYLLEKIDTDWYRGNCRNQIGIFPANYVKVIIDIP 556
Query: 232 E 232
E
Sbjct: 557 E 557
Score = 59.3 bits (142), Expect = 5e-09
Identities = 24/55 (43%), Positives = 41/55 (74%)
Query: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILK 228
+A+AL+DF G ++ EL+FKAGD+I L ++ DW+ G + G +GIFP ++++ L+
Sbjct: 734 KAKALYDFRGENEDELSFKAGDIITELESVDDDWMSGELMGKSGIFPKNYIQFLQ 788
Score = 52.0 bits (123), Expect = 8e-07
Identities = 26/68 (38%), Positives = 38/68 (55%)
Query: 158 KSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATG 217
K S + V+ + A EAL FT + +L+FK GD I +L R++ DW G ++ G
Sbjct: 649 KEDSGSNSQVNSLPAEWCEALHSFTAETSDDLSFKRGDRIQILERLDSDWCRGRLQDREG 708
Query: 218 IFPLSFVK 225
IFP FV+
Sbjct: 709 IFPAVFVR 716
Score = 30.0 bits (66), Expect = 3.2
Identities = 19/63 (30%), Positives = 30/63 (47%)
Query: 170 MAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKD 229
++ P A D + EL+ K GDV+ +L + ++LE TG LS +KI+
Sbjct: 415 LSVPHGIANEDIVSQNPGELSCKRGDVLVMLKQTENNYLECQKGEDTGRVHLSQMKIITP 474
Query: 230 FPE 232
E
Sbjct: 475 LDE 477
>gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens]
Length = 368
Score = 60.1 bits (144), Expect = 3e-09
Identities = 28/75 (37%), Positives = 45/75 (60%)
Query: 158 KSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATG 217
K + S+ + P +AL+DF + EL F GDVI L ++I+++W EG + G +G
Sbjct: 294 KPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSG 353
Query: 218 IFPLSFVKILKDFPE 232
FPLS+V++L P+
Sbjct: 354 FFPLSYVEVLVPLPQ 368
>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
Length = 352
Score = 58.9 bits (141), Expect = 6e-09
Identities = 28/70 (40%), Positives = 45/70 (64%), Gaps = 3/70 (4%)
Query: 162 PQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPL 221
P G +D+ P AL+DF ++ EL FK GD+I L ++I+++W EG + G +G FP+
Sbjct: 285 PSGVQMDQ---PCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPI 341
Query: 222 SFVKILKDFP 231
++V+IL P
Sbjct: 342 NYVEILVALP 351
>gi|51988887 SH3 domain containing ring finger 1 [Homo sapiens]
Length = 888
Score = 58.5 bits (140), Expect = 8e-09
Identities = 27/77 (35%), Positives = 47/77 (61%), Gaps = 2/77 (2%)
Query: 156 KVKSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGA 215
+V+S SP + ++ P A+AL+++ G +L F GD+I L +++++W G V G
Sbjct: 122 RVQSWSPPVRGIPQL--PCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGI 179
Query: 216 TGIFPLSFVKILKDFPE 232
G FP +FV+I+K P+
Sbjct: 180 HGFFPTNFVQIIKPLPQ 196
Score = 43.9 bits (102), Expect = 2e-04
Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 152 PRTRKVKSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGT 211
P + S+ P N + R + + S+ EL K GD++F+ + W +GT
Sbjct: 811 PPRQACSSLGPVLNESRPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGT 870
Query: 212 VR--GATGIFPLSFVK 225
++ G TG+FP SFV+
Sbjct: 871 LQRNGKTGLFPGSFVE 886
Score = 42.0 bits (97), Expect = 8e-04
Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 7/71 (9%)
Query: 173 PRAEALFDFTGNSKLE----LNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKI-- 226
P+ +AL+DF K L F DV+ ++ R++++W EG + GIFP+S+V+
Sbjct: 199 PQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNS 258
Query: 227 -LKDFPEEDDP 236
K E D P
Sbjct: 259 AAKQLIEWDKP 269
>gi|224586855 sorbin and SH3 domain containing 2 isoform 8 [Homo
sapiens]
Length = 492
Score = 58.2 bits (139), Expect = 1e-08
Identities = 26/62 (41%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEED 234
A+A++DF + EL+FK GD +++L +I+++W EG G GIFP+S+V+ L PE+
Sbjct: 260 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTP-PEKA 318
Query: 235 DP 236
P
Sbjct: 319 QP 320
Score = 52.0 bits (123), Expect = 8e-07
Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKILKDFPE 232
A A ++F ++ +EL+ + GD + LL R++++W EG + G GIFP+S+V+++K +
Sbjct: 335 AIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTK 394
Query: 233 --EDDPTNWLRCYYYEDTISTIKS 254
ED P + Y D I ++ S
Sbjct: 395 GAEDYPDPPIPHSYSSDRIHSLSS 418
Score = 34.3 bits (77), Expect = 0.17
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKIL 227
+AL+++T ++ EL + DVI ++ + + W GT R G FP ++VK L
Sbjct: 439 QALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 492
>gi|224586853 sorbin and SH3 domain containing 2 isoform 7 [Homo
sapiens]
Length = 1004
Score = 58.2 bits (139), Expect = 1e-08
Identities = 26/62 (41%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEED 234
A+A++DF + EL+FK GD +++L +I+++W EG G GIFP+S+V+ L PE+
Sbjct: 772 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTP-PEKA 830
Query: 235 DP 236
P
Sbjct: 831 QP 832
Score = 52.0 bits (123), Expect = 8e-07
Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKILKDFPE 232
A A ++F ++ +EL+ + GD + LL R++++W EG + G GIFP+S+V+++K +
Sbjct: 847 AIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTK 906
Query: 233 --EDDPTNWLRCYYYEDTISTIKS 254
ED P + Y D I ++ S
Sbjct: 907 GAEDYPDPPIPHSYSSDRIHSLSS 930
Score = 34.3 bits (77), Expect = 0.17
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKIL 227
+AL+++T ++ EL + DVI ++ + + W GT R G FP ++VK L
Sbjct: 951 QALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1004
>gi|224586851 sorbin and SH3 domain containing 2 isoform 6 [Homo
sapiens]
Length = 824
Score = 58.2 bits (139), Expect = 1e-08
Identities = 26/62 (41%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEED 234
A+A++DF + EL+FK GD +++L +I+++W EG G GIFP+S+V+ L PE+
Sbjct: 592 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTP-PEKA 650
Query: 235 DP 236
P
Sbjct: 651 QP 652
Score = 52.0 bits (123), Expect = 8e-07
Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKILKDFPE 232
A A ++F ++ +EL+ + GD + LL R++++W EG + G GIFP+S+V+++K +
Sbjct: 667 AIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTK 726
Query: 233 --EDDPTNWLRCYYYEDTISTIKS 254
ED P + Y D I ++ S
Sbjct: 727 GAEDYPDPPIPHSYSSDRIHSLSS 750
Score = 34.3 bits (77), Expect = 0.17
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKIL 227
+AL+++T ++ EL + DVI ++ + + W GT R G FP ++VK L
Sbjct: 771 QALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 824
>gi|224586849 sorbin and SH3 domain containing 2 isoform 5 [Homo
sapiens]
Length = 661
Score = 58.2 bits (139), Expect = 1e-08
Identities = 26/62 (41%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEED 234
A+A++DF + EL+FK GD +++L +I+++W EG G GIFP+S+V+ L PE+
Sbjct: 429 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTP-PEKA 487
Query: 235 DP 236
P
Sbjct: 488 QP 489
Score = 52.0 bits (123), Expect = 8e-07
Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKILKDFPE 232
A A ++F ++ +EL+ + GD + LL R++++W EG + G GIFP+S+V+++K +
Sbjct: 504 AIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTK 563
Query: 233 --EDDPTNWLRCYYYEDTISTIKS 254
ED P + Y D I ++ S
Sbjct: 564 GAEDYPDPPIPHSYSSDRIHSLSS 587
Score = 34.3 bits (77), Expect = 0.17
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKIL 227
+AL+++T ++ EL + DVI ++ + + W GT R G FP ++VK L
Sbjct: 608 QALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 661
>gi|224586846 sorbin and SH3 domain containing 2 isoform 4 [Homo
sapiens]
Length = 731
Score = 58.2 bits (139), Expect = 1e-08
Identities = 26/62 (41%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEED 234
A+A++DF + EL+FK GD +++L +I+++W EG G GIFP+S+V+ L PE+
Sbjct: 499 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTP-PEKA 557
Query: 235 DP 236
P
Sbjct: 558 QP 559
Score = 52.0 bits (123), Expect = 8e-07
Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKILKDFPE 232
A A ++F ++ +EL+ + GD + LL R++++W EG + G GIFP+S+V+++K +
Sbjct: 574 AIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTK 633
Query: 233 --EDDPTNWLRCYYYEDTISTIKS 254
ED P + Y D I ++ S
Sbjct: 634 GAEDYPDPPIPHSYSSDRIHSLSS 657
Score = 34.3 bits (77), Expect = 0.17
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKIL 227
+AL+++T ++ EL + DVI ++ + + W GT R G FP ++VK L
Sbjct: 678 QALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 731
>gi|224586844 sorbin and SH3 domain containing 2 isoform 3 [Homo
sapiens]
Length = 644
Score = 58.2 bits (139), Expect = 1e-08
Identities = 26/62 (41%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEED 234
A+A++DF + EL+FK GD +++L +I+++W EG G GIFP+S+V+ L PE+
Sbjct: 412 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTP-PEKA 470
Query: 235 DP 236
P
Sbjct: 471 QP 472
Score = 52.0 bits (123), Expect = 8e-07
Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKILKDFPE 232
A A ++F ++ +EL+ + GD + LL R++++W EG + G GIFP+S+V+++K +
Sbjct: 487 AIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTK 546
Query: 233 --EDDPTNWLRCYYYEDTISTIKS 254
ED P + Y D I ++ S
Sbjct: 547 GAEDYPDPPIPHSYSSDRIHSLSS 570
Score = 34.3 bits (77), Expect = 0.17
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKIL 227
+AL+++T ++ EL + DVI ++ + + W GT R G FP ++VK L
Sbjct: 591 QALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 644
>gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]
Length = 347
Score = 58.2 bits (139), Expect = 1e-08
Identities = 29/95 (30%), Positives = 54/95 (56%), Gaps = 4/95 (4%)
Query: 141 EQVPQALRRLRPRTRKVKSVS---PQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVI 197
E P+ ++R V + S G+++ M P L+DF ++ EL FK GD+I
Sbjct: 254 EYKPRPVKRSSSELNGVSTTSVVKTTGSNIP-MDQPCCRGLYDFEPENQGELGFKEGDII 312
Query: 198 FLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPE 232
L ++I+++W EG + G +G FP+++V+++ P+
Sbjct: 313 TLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ 347
>gi|10947118 sorbin and SH3 domain containing 2 isoform 2 [Homo
sapiens]
Length = 1100
Score = 58.2 bits (139), Expect = 1e-08
Identities = 26/62 (41%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEED 234
A+A++DF + EL+FK GD +++L +I+++W EG G GIFP+S+V+ L PE+
Sbjct: 868 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTP-PEKA 926
Query: 235 DP 236
P
Sbjct: 927 QP 928
Score = 52.0 bits (123), Expect = 8e-07
Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKILKDFPE 232
A A ++F ++ +EL+ + GD + LL R++++W EG + G GIFP+S+V+++K +
Sbjct: 943 AIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTK 1002
Query: 233 --EDDPTNWLRCYYYEDTISTIKS 254
ED P + Y D I ++ S
Sbjct: 1003 GAEDYPDPPIPHSYSSDRIHSLSS 1026
Score = 34.3 bits (77), Expect = 0.17
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKIL 227
+AL+++T ++ EL + DVI ++ + + W GT R G FP ++VK L
Sbjct: 1047 QALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 1100
>gi|194733749 sorbin and SH3 domain containing 2 isoform 1 [Homo
sapiens]
Length = 666
Score = 58.2 bits (139), Expect = 1e-08
Identities = 26/62 (41%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEED 234
A+A++DF + EL+FK GD +++L +I+++W EG G GIFP+S+V+ L PE+
Sbjct: 434 AKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTP-PEKA 492
Query: 235 DP 236
P
Sbjct: 493 QP 494
Score = 52.0 bits (123), Expect = 8e-07
Identities = 28/84 (33%), Positives = 50/84 (59%), Gaps = 4/84 (4%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKILKDFPE 232
A A ++F ++ +EL+ + GD + LL R++++W EG + G GIFP+S+V+++K +
Sbjct: 509 AIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTK 568
Query: 233 --EDDPTNWLRCYYYEDTISTIKS 254
ED P + Y D I ++ S
Sbjct: 569 GAEDYPDPPIPHSYSSDRIHSLSS 592
Score = 34.3 bits (77), Expect = 0.17
Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Query: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKIL 227
+AL+++T ++ EL + DVI ++ + + W GT R G FP ++VK L
Sbjct: 613 QALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL 666
>gi|115298672 neutrophil cytosolic factor 1 [Homo sapiens]
Length = 390
Score = 57.8 bits (138), Expect = 1e-08
Identities = 56/212 (26%), Positives = 98/212 (46%), Gaps = 10/212 (4%)
Query: 31 EKRGFTS-HFVFVIEVKTKGGSKYLIYRRYRQFHALQSKLEERFGPDSKS-SALACTLPT 88
EKR S H+V++ VK + S+ ++YRR+ + + L+E F ++ + + +P
Sbjct: 15 EKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPH 74
Query: 89 LPAKVYVGVKQEIAEMRIPALNAYMKSLLSLPVWVLMDEDVRIFFYQSPYDSEQVPQALR 148
LPA + Q AE R L Y +L+SLP + + FF P D ++P +
Sbjct: 75 LPAPKWFD-GQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRP-DDLKLPTDNQ 132
Query: 149 RLRPRT----RKVKSVSPQGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRIN 204
+P T + KS + + RA A ++ T S++ L+ GDV+ ++ +
Sbjct: 133 TKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALS--TGDVVEVVEKSE 190
Query: 205 KDWLEGTVRGATGIFPLSFVKILKDFPEEDDP 236
W ++ G P SF++ L E +DP
Sbjct: 191 SGWWFCQMKAKRGWIPASFLEPLDSPDETEDP 222
>gi|78000163 sorbin and SH3 domain containing 1 isoform 3 [Homo
sapiens]
Length = 1292
Score = 57.4 bits (137), Expect = 2e-08
Identities = 46/158 (29%), Positives = 82/158 (51%), Gaps = 19/158 (12%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKILKDFPE 232
A A F+F G++++E++F+ G+ I LL +++++W EG + G + GIFP+++V ++K P
Sbjct: 872 AIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVIKR-PL 930
Query: 233 EDDPTNWLRCYYYEDTISTIKSVAWEGGACPAFLPSLRPLPLTSPSHGSLSHSKAPSGSQ 292
+P +++ + S + A P F + L +P+ SL HS+ +
Sbjct: 931 VKNPVDYM-------DLPFSSSPSRSATASPQFSSHSK---LITPAPSSLPHSRRALSPE 980
Query: 293 MSHNAVTSH---QRPGWPGQPHSPFPHPTPHFQPDASL 327
M +AVTS G PG+ P P P+AS+
Sbjct: 981 M--HAVTSEWISLTVGVPGRRSLALTPPLPPL-PEASI 1015
Score = 49.7 bits (117), Expect = 4e-06
Identities = 49/208 (23%), Positives = 80/208 (38%), Gaps = 44/208 (21%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKIL----KDF 230
A A FDF + EL + GD++++ +I+++W EG G GIFP +++++L K
Sbjct: 798 ARAKFDFKAQTLKELPLQKGDIVYIYKQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQ 857
Query: 231 PEEDDPTNWLR------------------CYYYEDTISTIKSV--AWEGGACP-----AF 265
P++ P L + + I+ ++ V W G P
Sbjct: 858 PKKLTPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGI 917
Query: 266 LPSL------RPLPLTSPSHGSLSHSKAPSGSQMSHNAVTSHQRPGWPGQPHSPFPHPTP 319
P RPL + L S +PS S + +SH + +P P P
Sbjct: 918 FPITYVDVIKRPLVKNPVDYMDLPFSSSPSRSATASPQFSSHSK------LITPAPSSLP 971
Query: 320 HFQPDASLLQPVTPLGTSRWRKISAALP 347
H L P TS W ++ +P
Sbjct: 972 H---SRRALSPEMHAVTSEWISLTVGVP 996
Score = 32.0 bits (71), Expect = 0.84
Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 2/54 (3%)
Query: 176 EALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGAT--GIFPLSFVKIL 227
+AL+ + + EL + GD++ ++ + + W GT R G FP ++VK L
Sbjct: 1237 QALYSYIPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTKQFGTFPGNYVKPL 1290
>gi|222446607 SH3 domain containing ring finger 2 [Homo sapiens]
Length = 729
Score = 56.6 bits (135), Expect = 3e-08
Identities = 32/94 (34%), Positives = 50/94 (53%), Gaps = 6/94 (6%)
Query: 173 PRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPE 232
PRA+AL ++ G + +L F GD+I L +++++W +G + G +G FP S V+++K P+
Sbjct: 128 PRAKALCNYRGQNPGDLRFNKGDIILLRRQLDENWYQGEINGISGNFPASSVEVIKQLPQ 187
Query: 233 EDDPTNWLRCYYYEDTISTIKSVAWEGGACPAFL 266
P R Y D KS E C FL
Sbjct: 188 ---PPPLCRALYNFDLRGKDKS---ENQDCLTFL 215
Score = 42.0 bits (97), Expect = 8e-04
Identities = 22/56 (39%), Positives = 32/56 (57%), Gaps = 4/56 (7%)
Query: 174 RAEALFDFTGNSKLE----LNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
RA FD G K E L F D+I ++SR++++W EG + GIFP+ FV+
Sbjct: 193 RALYNFDLRGKDKSENQDCLTFLKDDIITVISRVDENWAEGKLGDKVGIFPILFVE 248
>gi|189083742 neutrophil cytosolic factor 2 [Homo sapiens]
Length = 526
Score = 55.8 bits (133), Expect = 5e-08
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
+ EALF + +L F+ GD+I +LS++N++WLEG +G GIFP FV+
Sbjct: 461 QVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
Score = 34.3 bits (77), Expect = 0.17
Identities = 14/48 (29%), Positives = 26/48 (54%)
Query: 178 LFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
LF F +K EL G+++F+L + N +W G G+ P ++++
Sbjct: 248 LFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 295
>gi|67189970 neutrophil cytosolic factor 2 [Homo sapiens]
Length = 526
Score = 55.8 bits (133), Expect = 5e-08
Identities = 23/52 (44%), Positives = 35/52 (67%)
Query: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
+ EALF + +L F+ GD+I +LS++N++WLEG +G GIFP FV+
Sbjct: 461 QVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVE 512
Score = 34.3 bits (77), Expect = 0.17
Identities = 14/48 (29%), Positives = 26/48 (54%)
Query: 178 LFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
LF F +K EL G+++F+L + N +W G G+ P ++++
Sbjct: 248 LFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLE 295
>gi|155030230 sorbin and SH3 domain containing 3 isoform 1 [Homo
sapiens]
Length = 671
Score = 53.5 bits (127), Expect = 3e-07
Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 3/79 (3%)
Query: 152 PRTRKVKSVSPQGNSVDRMAAPRAEAL---FDFTGNSKLELNFKAGDVIFLLSRINKDWL 208
P + + S S G S R + +A FDF S EL + GD++++ ++K+WL
Sbjct: 359 PSSTRDPSASNGGGSPARREEKKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWL 418
Query: 209 EGTVRGATGIFPLSFVKIL 227
EG G GIFP ++V++L
Sbjct: 419 EGEHHGRLGIFPANYVEVL 437
Score = 48.1 bits (113), Expect = 1e-05
Identities = 21/57 (36%), Positives = 39/57 (68%), Gaps = 2/57 (3%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGA--TGIFPLSFVKILKD 229
A A + F G+ ++EL+F+ G+ I L+ ++N++W EG + G GIFP S+V++ ++
Sbjct: 459 AVAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQVSRE 515
>gi|65301112 sorbin and SH3 domain containing 3 isoform 2 [Homo
sapiens]
Length = 329
Score = 53.5 bits (127), Expect = 3e-07
Identities = 27/79 (34%), Positives = 43/79 (54%), Gaps = 3/79 (3%)
Query: 152 PRTRKVKSVSPQGNSVDRMAAPRAEAL---FDFTGNSKLELNFKAGDVIFLLSRINKDWL 208
P + + S S G S R + +A FDF S EL + GD++++ ++K+WL
Sbjct: 17 PSSTRDPSASNGGGSPARREEKKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWL 76
Query: 209 EGTVRGATGIFPLSFVKIL 227
EG G GIFP ++V++L
Sbjct: 77 EGEHHGRLGIFPANYVEVL 95
Score = 48.1 bits (113), Expect = 1e-05
Identities = 21/57 (36%), Positives = 39/57 (68%), Gaps = 2/57 (3%)
Query: 175 AEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGA--TGIFPLSFVKILKD 229
A A + F G+ ++EL+F+ G+ I L+ ++N++W EG + G GIFP S+V++ ++
Sbjct: 117 AVAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQVSRE 173
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 52.8 bits (125), Expect = 5e-07
Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 177 ALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDDP 236
A++D+ N++ EL+F G +I ++++ + DW +G + G TG+FP ++VK+ D D
Sbjct: 1107 AMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTD---SDPS 1163
Query: 237 TNWLRCYYYEDTISTIK 253
W DT+ I+
Sbjct: 1164 QQWCADLQTLDTMQPIE 1180
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 7/78 (8%)
Query: 153 RTRKVKSVSP---QGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLE 209
RT SVSP QG V+ + +A+AL +T LNF D+I +L + ++W
Sbjct: 854 RTVSPGSVSPIHGQGQVVENL---KAQALCSWTAKKDNHLNFSKHDIITVLEQ-QENWWF 909
Query: 210 GTVRGATGIFPLSFVKIL 227
G V G G FP S+VKI+
Sbjct: 910 GEVHGGRGWFPKSYVKII 927
Score = 32.7 bits (73), Expect = 0.49
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query: 135 QSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAE--ALFDFTGNSKLELNFK 192
Q E++ + R+ + RK K A+ AL+ F + E++F
Sbjct: 693 QEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFN 752
Query: 193 AGDVIFLLSRI--NKDWLEGTVRGATGIFPLSFVK 225
+GD+I + + WL G+ +G G FP ++V+
Sbjct: 753 SGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVE 787
Score = 30.8 bits (68), Expect = 1.9
Identities = 15/49 (30%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
Query: 177 ALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
AL+ ++ +L F G+ I L+++ + +W G++ +GIFP ++VK
Sbjct: 961 ALYPYSSVEPGDLTFTEGEEI-LVTQKDGEWWTGSIGDRSGIFPSNYVK 1008
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 52.8 bits (125), Expect = 5e-07
Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 177 ALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDDP 236
A++D+ N++ EL+F G +I ++++ + DW +G + G TG+FP ++VK+ D D
Sbjct: 1134 AMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTD---SDPS 1190
Query: 237 TNWLRCYYYEDTISTIK 253
W DT+ I+
Sbjct: 1191 QQWCADLQTLDTMQPIE 1207
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 7/78 (8%)
Query: 153 RTRKVKSVSP---QGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLE 209
RT SVSP QG V+ + +A+AL +T LNF D+I +L + ++W
Sbjct: 881 RTVSPGSVSPIHGQGQVVENL---KAQALCSWTAKKDNHLNFSKHDIITVLEQ-QENWWF 936
Query: 210 GTVRGATGIFPLSFVKIL 227
G V G G FP S+VKI+
Sbjct: 937 GEVHGGRGWFPKSYVKII 954
Score = 32.7 bits (73), Expect = 0.49
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query: 135 QSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAE--ALFDFTGNSKLELNFK 192
Q E++ + R+ + RK K A+ AL+ F + E++F
Sbjct: 720 QEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFN 779
Query: 193 AGDVIFLLSRI--NKDWLEGTVRGATGIFPLSFVK 225
+GD+I + + WL G+ +G G FP ++V+
Sbjct: 780 SGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVE 814
Score = 30.8 bits (68), Expect = 1.9
Identities = 15/49 (30%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
Query: 177 ALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
AL+ ++ +L F G+ I L+++ + +W G++ +GIFP ++VK
Sbjct: 988 ALYPYSSVEPGDLTFTEGEEI-LVTQKDGEWWTGSIGDRSGIFPSNYVK 1035
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 52.8 bits (125), Expect = 5e-07
Identities = 24/77 (31%), Positives = 44/77 (57%), Gaps = 3/77 (3%)
Query: 177 ALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEEDDP 236
A++D+ N++ EL+F G +I ++++ + DW +G + G TG+FP ++VK+ D D
Sbjct: 1134 AMYDYAANNEDELSFSKGQLINVMNKDDPDWWQGEINGVTGLFPSNYVKMTTD---SDPS 1190
Query: 237 TNWLRCYYYEDTISTIK 253
W DT+ I+
Sbjct: 1191 QQWCADLQTLDTMQPIE 1207
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/78 (38%), Positives = 42/78 (53%), Gaps = 7/78 (8%)
Query: 153 RTRKVKSVSP---QGNSVDRMAAPRAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLE 209
RT SVSP QG V+ + +A+AL +T LNF D+I +L + ++W
Sbjct: 881 RTVSPGSVSPIHGQGQVVENL---KAQALCSWTAKKDNHLNFSKHDIITVLEQ-QENWWF 936
Query: 210 GTVRGATGIFPLSFVKIL 227
G V G G FP S+VKI+
Sbjct: 937 GEVHGGRGWFPKSYVKII 954
Score = 32.7 bits (73), Expect = 0.49
Identities = 23/95 (24%), Positives = 42/95 (44%), Gaps = 4/95 (4%)
Query: 135 QSPYDSEQVPQALRRLRPRTRKVKSVSPQGNSVDRMAAPRAE--ALFDFTGNSKLELNFK 192
Q E++ + R+ + RK K A+ AL+ F + E++F
Sbjct: 720 QEEKTQEKIQEEERKAEEKQRKDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFN 779
Query: 193 AGDVIFLLSRI--NKDWLEGTVRGATGIFPLSFVK 225
+GD+I + + WL G+ +G G FP ++V+
Sbjct: 780 SGDIIQVDEKTVGEPGWLYGSFQGNFGWFPCNYVE 814
Score = 30.8 bits (68), Expect = 1.9
Identities = 15/49 (30%), Positives = 30/49 (61%), Gaps = 1/49 (2%)
Query: 177 ALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVK 225
AL+ ++ +L F G+ I L+++ + +W G++ +GIFP ++VK
Sbjct: 988 ALYPYSSVEPGDLTFTEGEEI-LVTQKDGEWWTGSIGDRSGIFPSNYVK 1035
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 52.4 bits (124), Expect = 6e-07
Identities = 25/58 (43%), Positives = 36/58 (62%)
Query: 177 ALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKILKDFPEED 234
AL+ F EL+F+ GD I +L+ + WLEG+++G TGIFP FVK+ D E+
Sbjct: 250 ALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFVKLCPDTRVEE 307
Score = 43.5 bits (101), Expect = 3e-04
Identities = 21/54 (38%), Positives = 30/54 (55%)
Query: 174 RAEALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKIL 227
+A AL + EL+F+ GDVI ++ W EG + G GIFP FV++L
Sbjct: 149 QARALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVELL 202
Score = 41.2 bits (95), Expect = 0.001
Identities = 21/51 (41%), Positives = 31/51 (60%)
Query: 177 ALFDFTGNSKLELNFKAGDVIFLLSRINKDWLEGTVRGATGIFPLSFVKIL 227
A+FDF + EL GD+I +L+ +++ WL G TG FP SFV+I+
Sbjct: 9 AIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIV 59
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,493,438
Number of Sequences: 37866
Number of extensions: 749287
Number of successful extensions: 3783
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 163
Number of HSP's that attempted gapping in prelim test: 3383
Number of HSP's gapped (non-prelim): 508
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.