Search of human proteins with 16306576

Search of human proteins with 16306576

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1
[Homo sapiens]
         (539 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H...  1096   0.0  
gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [H...  1077   0.0  
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]      81   3e-15
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]     69   8e-12
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]    65   2e-10
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]    63   8e-10
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]     62   1e-09
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ...    52   1e-06
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ...    52   2e-06
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ...    51   2e-06
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ...    51   2e-06
gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens]     48   2e-05
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]    46   1e-04
gi|117938759 GNAS complex locus XLas [Homo sapiens]                    45   2e-04
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi...    45   2e-04
gi|116268109 nucleotide-binding oligomerization domains 27 [Homo...    42   0.001
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    41   0.002
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...    41   0.002
gi|24308207 leucine rich repeat containing 47 [Homo sapiens]           41   0.003
gi|157168349 F-box and leucine-rich repeat protein 19 [Homo sapi...    41   0.003
gi|239750101 PREDICTED: hypothetical protein [Homo sapiens]            40   0.004
gi|18699730 solute carrier family 16, member 10 [Homo sapiens]         40   0.004
gi|30520327 F-box protein 27 [Homo sapiens]                            40   0.004
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]            40   0.005
gi|4505101 microtubule-associated protein 7 [Homo sapiens]             40   0.005
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    40   0.007
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              40   0.007
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    40   0.007
gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]             40   0.007
gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]             40   0.007

>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
           sapiens]
          Length = 539

 Score = 1096 bits (2835), Expect = 0.0
 Identities = 539/539 (100%), Positives = 539/539 (100%)

Query: 1   MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
           MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ
Sbjct: 1   MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60

Query: 61  RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
           RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL
Sbjct: 61  RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120

Query: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
           VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK
Sbjct: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180

Query: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVM 240
           LLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVM
Sbjct: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVM 240

Query: 241 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 300
           LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL
Sbjct: 241 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 300

Query: 301 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 360
           QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE
Sbjct: 301 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 360

Query: 361 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 420
           LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT
Sbjct: 361 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 420

Query: 421 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 480
           SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL
Sbjct: 421 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 480

Query: 481 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 539
           RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS
Sbjct: 481 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 539


>gi|61742136 F-box and leucine-rich repeat protein 6 isoform 2 [Homo
           sapiens]
          Length = 533

 Score = 1077 bits (2786), Expect = 0.0
 Identities = 533/539 (98%), Positives = 533/539 (98%), Gaps = 6/539 (1%)

Query: 1   MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60
           MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ
Sbjct: 1   MAAPASRQVRRRARAAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQ 60

Query: 61  RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120
           RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL
Sbjct: 61  RRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEIL 120

Query: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180
           VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK
Sbjct: 121 VQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKK 180

Query: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVM 240
           LLASLEWLMPNRFSQLQRLTLIHWKSQ      LVGECCPRLTFLKLSGCHGVTADALVM
Sbjct: 181 LLASLEWLMPNRFSQLQRLTLIHWKSQ------LVGECCPRLTFLKLSGCHGVTADALVM 234

Query: 241 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 300
           LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL
Sbjct: 235 LAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQL 294

Query: 301 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 360
           QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE
Sbjct: 295 QVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEE 354

Query: 361 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 420
           LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT
Sbjct: 355 LCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT 414

Query: 421 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 480
           SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL
Sbjct: 415 SDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNL 474

Query: 481 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 539
           RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS
Sbjct: 475 RGTRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLKRAYRGLEEVQWCLEQLLTSPSPS 533


>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
          Length = 491

 Score = 80.9 bits (198), Expect = 3e-15
 Identities = 106/418 (25%), Positives = 164/418 (39%), Gaps = 74/418 (17%)

Query: 113 DRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAK 172
           DR+P   +VQIF  L     P   L R ARVCRRW   A  P LW T+ L+   +     
Sbjct: 115 DRLPDHSMVQIFSFL-----PTNQLCRCARVCRRWYNLAWDPRLWRTIRLTGETINVD-- 167

Query: 173 GGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHG 232
              +A K L   L    PN    L+ +T+   +      L  + +CCP L  L++SGC+ 
Sbjct: 168 ---RALKVLTRRLCQDTPNVCLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYN 224

Query: 233 VTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRM-----RKLWLTYSSQTTA 287
           ++ +A+  +   C  L  LD+  S       +S   EA  ++     +++ + Y   T  
Sbjct: 225 ISNEAVFDVVSLCPNLEHLDV--SGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDC 282

Query: 288 ILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGR 347
                         VLE   G++            +   C QL  L L   + L     R
Sbjct: 283 F-------------VLE-DEGLH-----------TIAAHCTQLTHLYLRRCVRLTDEGLR 317

Query: 348 GVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP- 406
            +       S++EL +  S C FVS+  L  +      LR L +  C R+T  G++ +  
Sbjct: 318 YLV--IYCASIKELSV--SDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAK 373

Query: 407 -CRELEQLHL-GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAF 464
            C +L  L+  G  G +D       G  +L  K C  L+ LD+                 
Sbjct: 374 YCSKLRYLNARGCEGITD------HGVEYLA-KNCTKLKSLDI------------GKCPL 414

Query: 465 LSTPGGSHPALCSLNLRG------TRVTPSTVSSVISSCPGLLYLNLESCRCLPRGLK 516
           +S  G    AL   NL+         +T   +  V ++C  L  LN++ C      L+
Sbjct: 415 VSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNVQDCEVSVEALR 472


>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
          Length = 621

 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 84/353 (23%), Positives = 142/353 (40%), Gaps = 39/353 (11%)

Query: 105 EGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSS 164
           EGP+ G+ D++P E++  I   L      +P L R A+ C+   +    P  +  + L  
Sbjct: 273 EGPNNGYFDKLPYELIQLILNHLT-----LPDLCRLAQTCKLLSQHCCDPLQYIHLNLQ- 326

Query: 165 PLVGRPAKGGVKAEKKLLASLEWLMPN--------------RF-----SQLQRLTLIHWK 205
           P   +     ++  +     ++WL  +              RF     S+L RL L    
Sbjct: 327 PYWAKLDDTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSH 386

Query: 206 SQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVS 265
                 L+++ E CP L  L LS C  +   A   +AK  C L  L L  + VE TA++S
Sbjct: 387 FLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAK-LCSLKRLVLYRTKVEQTALLS 445

Query: 266 FLEEAGSRMR-KLWLTYSSQTTAILGALLGSCCPQLQVLEV--STGINRNSIPLQLPVEA 322
            L          L      +   ++ +++G+ C +L+ L++     I  N I        
Sbjct: 446 ILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENGI------AE 499

Query: 323 LQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHG 382
           L  GCP L+ L L     L    G         P+L++L L ++    V +  +  L   
Sbjct: 500 LASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTAN--RSVCDTDIDELACN 557

Query: 383 SPNLRLLDLRGCARITPAGLQDL--PCRELEQLHLGLYGTSDRLTLAKEGSPF 433
              L+ LD+ G   ++PA L+ L   C++L  L +      D   + +  + F
Sbjct: 558 CTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAVLELNASF 610



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 70/308 (22%), Positives = 122/308 (39%), Gaps = 43/308 (13%)

Query: 218 CCPRLTFLKLS---GCHGVTADALVMLAKACCQLHSLDLQ----HSMVESTAVVSFLEEA 270
           CC  L ++ L+       +   +L  L   C  +  L+L        +       FL+  
Sbjct: 314 CCDPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLKVC 373

Query: 271 GSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL 330
           GS + +L L+ S         ++   CP LQ L +S+         +LP +A        
Sbjct: 374 GSELVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCD-------KLPPQAFNHIAKLC 426

Query: 331 QVLRLLNLMWLPKPPGRGVAPGPGFPS-LEELCLASSTCNFVSN-EVLGRLLHGS-PNLR 387
            + RL+  ++  K     +     F S L+ L L S  C  + + +V+  ++      LR
Sbjct: 427 SLKRLV--LYRTKVEQTALLSILNFCSELQHLSLGS--CVMIEDYDVIASMIGAKCKKLR 482

Query: 388 LLDLRGCARITPAGLQDLP--CRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLREL 445
            LDL  C  IT  G+ +L   C  LE+L LG   T        + S     +  H L  L
Sbjct: 483 TLDLWRCKNITENGIAELASGCPLLEELDLGWCPTL-------QSSTGCFTRLAHQLPNL 535

Query: 446 D----LSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNLRGTR-VTPSTVSSVISSCPGL 500
                 + +   + D+++           +   L  L++ GTR V+P+++  ++ SC  L
Sbjct: 536 QKLFLTANRSVCDTDIDELAC--------NCTRLQQLDILGTRMVSPASLRKLLESCKDL 587

Query: 501 LYLNLESC 508
             L++  C
Sbjct: 588 SLLDVSFC 595



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 33/107 (30%), Positives = 42/107 (39%), Gaps = 7/107 (6%)

Query: 407 CRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLS 466
           C  L+ +HL L     +L    + S    Q  C  ++ L+LS  G          + FL 
Sbjct: 315 CDPLQYIHLNLQPYWAKLD---DTSLEFLQSRCTLVQWLNLSWTGNRGFISVAGFSRFLK 371

Query: 467 TPGGSHPALCSLNLRGTRVTPSTVSSVISS-CPGLLYLNLESCRCLP 512
             G     L  L L  +     T   VIS  CP L  LNL SC  LP
Sbjct: 372 VCGSE---LVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLP 415


>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
          Length = 436

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 99/432 (22%), Positives = 163/432 (37%), Gaps = 43/432 (9%)

Query: 114 RIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
           ++P E+L++IF  L         L R A+V R W   A   + W  + L      R  +G
Sbjct: 27  KLPKELLLRIFSFLDVVT-----LCRCAQVSRAWNVLALDGSNWQRIDLFD--FQRDIEG 79

Query: 174 GVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGV 233
            V         +E +       L++L+L          L+   + C  +  L L+GC   
Sbjct: 80  RV---------VENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKT 130

Query: 234 TADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALL 293
           T      L+K C +L  LDL      +   +  L E    + +L +++  Q T      L
Sbjct: 131 TDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQAL 190

Query: 294 GSCCPQLQVLEVSTGINRNSIPLQLPVEALQ---KGCPQLQVLRLLNLMWLPKPPGRGVA 350
              C  L+ L +           QL  EAL+     CP+L  L L   + +       + 
Sbjct: 191 VRGCGGLKALFLKG-------CTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITIC 243

Query: 351 PGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CR 408
              G   L+ LC  +S C+ +++ +L  L    P LR+L++  C+++T  G   L   C 
Sbjct: 244 --RGCHKLQSLC--ASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCH 299

Query: 409 ELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTP 468
           ELE++ L      +      + +       C  L+ L LS       D        L   
Sbjct: 300 ELEKMDL------EECVQITDSTLIQLSIHCPRLQVLSLSHCELITDD----GIRHLGNG 349

Query: 469 GGSHPALCSLNLRGTRVTPSTVSSVISSCPGLLYLNLESCRCLPR-GLKRAYRGLEEVQW 527
             +H  L  + L    +        + SC  L  + L  C+ + R G+KR    L  ++ 
Sbjct: 350 ACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKV 409

Query: 528 CLEQLLTSPSPS 539
                  +P PS
Sbjct: 410 HAYFAPVTPPPS 421


>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
          Length = 418

 Score = 62.8 bits (151), Expect = 8e-10
 Identities = 101/404 (25%), Positives = 165/404 (40%), Gaps = 70/404 (17%)

Query: 118 EILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKA 177
           E+L  IFG L   D      GRAA+VC  W++AA   ++W                GV+A
Sbjct: 11  ELLAMIFGYLDVRDK-----GRAAQVCTAWRDAAYHKSVWR---------------GVEA 50

Query: 178 EKKLLASLEWLMPNRFSQ-LQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTAD 236
           +  L  +   L P+  ++ ++R+ ++  +  +  V++ +      +  L LSGC+ +T +
Sbjct: 51  KLHLRRANPSLFPSLQARGIRRVQILSLRRSLSYVIQGMA----NIESLNLSGCYNLTDN 106

Query: 237 ALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSC 296
            L                          +F++E GS +R L L+   Q T      +   
Sbjct: 107 GLGH------------------------AFVQEIGS-LRALNLSLCKQITDSSLGRIAQY 141

Query: 297 CPQLQVLEVSTGINRNSIPLQLPVEALQK-GCPQLQVLRLLNLMWLPKPPGRGVAPGPGF 355
              L+VLE+    N  +  L L    LQ+     L+  R L+ + +    G   +   G 
Sbjct: 142 LKGLEVLELGGCSNITNTGLLLIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGC 201

Query: 356 PSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHL 415
             LE+L L    C  +++  L  +  G   LRLL+L  C  I+ AGL          LHL
Sbjct: 202 LGLEQLTL--QDCQKLTDLSLKHISRGLTGLRLLNLSFCGGISDAGL----------LHL 249

Query: 416 GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSG--QGFSEKDLEQALAAFLSTPGGSHP 473
              G+   L L    +   T      +  L LSG    F +K  +Q+LA       G   
Sbjct: 250 SHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLSGLDVSFCDKVGDQSLAYIAQGLDG--- 306

Query: 474 ALCSLNLRGTRVTPSTVSSVISSCPGLLYLNLESC-RCLPRGLK 516
            L SL+L    ++   ++ ++    GL  LN+  C R   +GL+
Sbjct: 307 -LKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVRITDKGLE 349


>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
          Length = 423

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 101/417 (24%), Positives = 162/417 (38%), Gaps = 39/417 (9%)

Query: 114 RIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
           ++P E+L++IF  L      +  L R A++ + W   A   + W  + L +  +    +G
Sbjct: 14  KLPKELLLRIFSFL-----DIVTLCRCAQISKAWNILALDGSNWQRIDLFNFQID--VEG 66

Query: 174 GVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGV 233
            V         +E +       L++L+L          LK   + C  +  L L+GC  +
Sbjct: 67  RV---------VENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKI 117

Query: 234 TADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALL 293
           T      L++ C +L  LDL   +  + + +  + E    +  L L++  Q T      L
Sbjct: 118 TDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEAL 177

Query: 294 GSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVAP-G 352
              C  L+ L +  G        QL  EAL+        L  LNL    +    GV    
Sbjct: 178 VRGCRGLKAL-LLRGCT------QLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQIC 230

Query: 353 PGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CREL 410
            G   L+ LCL  S C+ +++  L  L    P L++L+   C+ +T AG   L   C EL
Sbjct: 231 RGCHRLQALCL--SGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHEL 288

Query: 411 EQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGG 470
           E++ L      +   L  + +       C  L+ L LS       D        LS    
Sbjct: 289 EKMDL------EECILITDSTLIQLSIHCPKLQALSLSHCELITDD----GILHLSNSTC 338

Query: 471 SHPALCSLNLRGTRVTPSTVSSVISSCPGLLYLNLESCRCLPR-GLKRAYRGLEEVQ 526
            H  L  L L    +        + +C GL  L L  C+ + R G+KR    L  V+
Sbjct: 339 GHERLRVLELDNCLLITDVALEHLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395


>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 72/317 (22%), Positives = 115/317 (36%), Gaps = 65/317 (20%)

Query: 188 LMPNRFSQLQRLTLIHWKSQVHPVLKLV--GECCPRLTFLKLSGCHGVTADALVMLAKAC 245
           L+P  F  LQ L+L + +      L+ +  G  C +L +L LSGC  ++      +A +C
Sbjct: 290 LLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSC 349

Query: 246 CQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSC--------- 296
             +  L +      +   V  L E  SR+  L  T +   +      L +C         
Sbjct: 350 TGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEG 409

Query: 297 ---------------CPQLQVLEVST--GINRNSIPLQLPVEALQKGCPQLQVLRLLNLM 339
                           P L  + ++   GI  +S+    P++       QL VL L N +
Sbjct: 410 NKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLK-------QLTVLNLANCV 462

Query: 340 WLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITP 399
            +     +    GP    + EL L  S C  +S+  + +L    PNL  L LR C  +T 
Sbjct: 463 RIGDMGLKQFLDGPASMRIRELNL--SNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTA 520

Query: 400 AGLQ-----------DLPCRELEQLHLGLYG----------------TSDRLTLAKEGSP 432
            G+            DL   ++    L +                  T D + +      
Sbjct: 521 QGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQITDSAME 580

Query: 433 FLTQKWCHTLRELDLSG 449
            L+ K CH L  LD+SG
Sbjct: 581 MLSAK-CHYLHILDISG 596


>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
           [Homo sapiens]
          Length = 735

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 58/243 (23%), Positives = 94/243 (38%), Gaps = 37/243 (15%)

Query: 188 LMPNRFSQLQRLTLIHWKSQVHPVLKLV--GECCPRLTFLKLSGCHGVTADALVMLAKAC 245
           L+P  F  LQ L+L + +      L+ +  G  C +L +L LSGC  ++      +A +C
Sbjct: 290 LLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSC 349

Query: 246 CQLHSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSC--------- 296
             +  L +      +   V  L E  SR+  L  T +   +      L +C         
Sbjct: 350 TGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEG 409

Query: 297 ---------------CPQLQVLEVST--GINRNSIPLQLPVEALQKGCPQLQVLRLLNLM 339
                           P L  + ++   GI  +S+    P++       QL VL L N +
Sbjct: 410 NKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLK-------QLTVLNLANCV 462

Query: 340 WLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITP 399
            +     +    GP    + EL L  S C  +S+  + +L    PNL  L LR C  +T 
Sbjct: 463 RIGDMGLKQFLDGPASMRIRELNL--SNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTA 520

Query: 400 AGL 402
            G+
Sbjct: 521 QGI 523



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 22/86 (25%), Positives = 43/86 (50%)

Query: 196 LQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQH 255
           L+ L + +       ++K +   C  LT L ++GC  +T  A+ ML+  C  LH LD+  
Sbjct: 582 LEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISG 641

Query: 256 SMVESTAVVSFLEEAGSRMRKLWLTY 281
            ++ +  ++  L+    ++R L + Y
Sbjct: 642 CVLLTDQILEDLQIGCKQLRILKMQY 667



 Score = 31.6 bits (70), Expect = 1.9
 Identities = 51/217 (23%), Positives = 85/217 (39%), Gaps = 26/217 (11%)

Query: 211 VLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEA 270
           V+KL  E CP L +L L  C  +TA  +  +      L S+DL  + + +  +       
Sbjct: 497 VMKL-SERCPNLNYLSLRNCEHLTAQGIGYIVNIF-SLVSIDLSGTDISNEGL-----NV 549

Query: 271 GSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL 330
            SR +KL     S+   I    + + C    +LE    ++  S    + ++AL   C  L
Sbjct: 550 LSRHKKLKELSVSECYRITDDGIQAFCKSSLILE-HLDVSYCSQLSDMIIKALAIYCINL 608

Query: 331 QVLRLLNLMWLPKPPGRGVAPGPGFPSLEELC-----LASSTCNFVSNEVLGRLLHGSPN 385
             L +      PK              L   C     L  S C  +++++L  L  G   
Sbjct: 609 TSLSIAGC---PK------ITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQ 659

Query: 386 LRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGTSD 422
           LR+L ++ C  I+    Q +  +  +Q     Y T+D
Sbjct: 660 LRILKMQYCTNISKKAAQRMSSKVQQQ----EYNTND 692


>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 424

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 48/185 (25%), Positives = 77/185 (41%), Gaps = 36/185 (19%)

Query: 99  PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158
           P    E  P   W D +P E+L+ IF  L      +P L + + VC+RW   AS  +LW 
Sbjct: 85  PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138

Query: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRFS--QLQRLTLIHWKSQVHPV 211
           T+ L+       + GR    GV A +   + ++  +   FS  ++Q + L +   +V  +
Sbjct: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198

Query: 212 LKLVGECC-----------------------PRLTFLKLSGCHGVTADALVMLAKACCQL 248
             ++ +C                          L  L LSGC G +  AL  L  +C +L
Sbjct: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258

Query: 249 HSLDL 253
             L+L
Sbjct: 259 DELNL 263


>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 410

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 48/185 (25%), Positives = 77/185 (41%), Gaps = 36/185 (19%)

Query: 99  PTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH 158
           P    E  P   W D +P E+L+ IF  L      +P L + + VC+RW   AS  +LW 
Sbjct: 85  PKLNRENFPGVSW-DSLPDELLLGIFSCLC-----LPELLKVSGVCKRWYRLASDESLWQ 138

Query: 159 TVTLSS-----PLVGRPAKGGVKAEKKLLASLEWLMPNRFS--QLQRLTLIHWKSQVHPV 211
           T+ L+       + GR    GV A +   + ++  +   FS  ++Q + L +   +V  +
Sbjct: 139 TLDLTGKNLHPDVTGRLLSQGVIAFRCPRSFMDQPLAEHFSPFRVQHMDLSNSVIEVSTL 198

Query: 212 LKLVGECC-----------------------PRLTFLKLSGCHGVTADALVMLAKACCQL 248
             ++ +C                          L  L LSGC G +  AL  L  +C +L
Sbjct: 199 HGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGCSGFSEFALQTLLSSCSRL 258

Query: 249 HSLDL 253
             L+L
Sbjct: 259 DELNL 263


>gi|22547146 F-box and leucine-rich repeat protein 8 [Homo sapiens]
          Length = 374

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 70/245 (28%), Positives = 99/245 (40%), Gaps = 42/245 (17%)

Query: 112 GDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSP------ 165
           G+ +P E+L  IF  L   D        AARVCR W  AA+  A+WH   +S        
Sbjct: 5   GEGLPEEVLALIFRHLSLRDR-----AAAARVCRAWAAAATCSAVWHDTKISCECELEGM 59

Query: 166 ----------------LVGRPAKGGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQV- 208
                           L   P++   K  ++    L  ++  R   L+ L L     +  
Sbjct: 60  LPPYLSACLDHIHNLRLEFEPSR---KPSRRAAIELLMVLAGRAPGLRGLRLECRGEKPL 116

Query: 209 ----HPVLKLVGECC---PRLTFLKLSGCHGVTADALVM-LAKACCQLHSLDLQHS-MVE 259
                 VL+ V   C    +L  L L        DALV+  A++C +LHSL L +S +V 
Sbjct: 117 FDAGRDVLEAVHAVCGAASQLRHLDLRRLSFTLDDALVLQAARSCPELHSLFLDNSTLVG 176

Query: 260 STAVVSFLE--EAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQ 317
           S    S LE  EA  R+R L L  +S + AIL AL         +L +      ++    
Sbjct: 177 SVGPGSVLELLEACPRLRALGLHLASLSHAILEALAAPDRAPFALLALRCACPEDARASP 236

Query: 318 LPVEA 322
           LP EA
Sbjct: 237 LPNEA 241


>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
          Length = 479

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 97/398 (24%), Positives = 140/398 (35%), Gaps = 75/398 (18%)

Query: 63  ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLE---- 118
           A++  P QPP  P+      A   S AA A  P      TP  GP +      P E    
Sbjct: 41  ATKNRPCQPPPPPTLPPPSLAAPLSRAALAGGPC-----TPAGGPASALAPGHPAERPPL 95

Query: 119 -----ILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWH--TVTLSSPLVGRPA 171
                IL  +F    A +  +      A+VC+ W+    QP  W   T  L +  +    
Sbjct: 96  ATDEKILNGLFWYFSACEKCV-----LAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVL 150

Query: 172 KGGVKAEKKL------------------LASLEWLMPNRFSQ-------LQRLTLIH--- 203
            GG K    L                  L   E++     S+       L+R T+     
Sbjct: 151 PGGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGL 210

Query: 204 --WKSQVHPVLKLVGECC-------------PRLTFLKLSGCHGVTADALVMLAKACCQL 248
                Q+  V++L    C              R+T L +S C  V  DA+  +++    L
Sbjct: 211 EVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNL 270

Query: 249 HSLDLQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTG 308
             L LQ   V  TA+  F    G     L L    + T      +    P L  L +S  
Sbjct: 271 AELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGC 330

Query: 309 INRNSIPLQLPVEALQKGCPQLQVLRLLNLMWLPKPPGRGVA-PGPGFPSLEELCLASST 367
                  ++L  E L+K       LR L+L W P+     +         LEEL L    
Sbjct: 331 SKVTDDGVELVAENLRK-------LRSLDLSWCPRITDMALEYVACDLHRLEELVL--DR 381

Query: 368 CNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDL 405
           C  +++  L  L   S +LR L LR C ++   GL+ L
Sbjct: 382 CVRITDTGLSYLSTMS-SLRSLYLRWCCQVQDFGLKHL 418



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 40/149 (26%), Positives = 64/149 (42%), Gaps = 18/149 (12%)

Query: 204 WKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLD----------- 252
           W+   H V+ +V    P LT L LSGC  VT D + ++A+   +L SLD           
Sbjct: 305 WEITNHGVVNVV-HSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMA 363

Query: 253 LQHSMVESTAVVSFLEEAGSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRN 312
           L++   +   +   + +   R+    L+Y S  +++    L  CC Q+Q   +   +   
Sbjct: 364 LEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCC-QVQDFGLKHLLALG 422

Query: 313 SIPLQLPVEALQKGCPQLQVLRLLNLMWL 341
           S+ L  P      GCP L    L  L+ L
Sbjct: 423 SLRLLSPA-----GCPLLTTTGLSGLVQL 446



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 47/169 (27%), Positives = 69/169 (40%), Gaps = 25/169 (14%)

Query: 356 PSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLPC--RELEQL 413
           P+L  L L  S C+ V+++ +  +      LR LDL  C RIT   L+ + C    LE+L
Sbjct: 320 PNLTALSL--SGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEEL 377

Query: 414 HLGL------YGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLST 467
            L         G S   T++   S +L  +WC  +       Q F  K L    +  L +
Sbjct: 378 VLDRCVRITDTGLSYLSTMSSLRSLYL--RWCCQV-------QDFGLKHLLALGSLRLLS 428

Query: 468 PGGSHPALCSLNLRGTRVTPSTVSSVISSCPG-----LLYLNLESCRCL 511
           P G  P L +  L G           +++CPG       Y +    RCL
Sbjct: 429 PAGC-PLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCL 476


>gi|117938759 GNAS complex locus XLas [Homo sapiens]
          Length = 1037

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 48/173 (27%), Positives = 64/173 (36%), Gaps = 25/173 (14%)

Query: 16  APRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQRRASRRTPRQPPRGP 75
           +P P  A  + +D+ A RG    LLQ   +        P  P A        P  PP  P
Sbjct: 155 SPPPEEAMPFEFDQPAQRGCSQLLLQVPDL-------APGGPGAAG-----VPGAPPEEP 202

Query: 76  SAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMP 135
            A    KAG R       +P P  T  P E    G+GD  P   L ++   +   DG   
Sbjct: 203 QALRPAKAGSRG----GYSPPPEET-MPFELDGEGFGDDSPPPGLSRV---IAQVDGSSQ 254

Query: 136 FLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKGGVKAEKKLLASLEWL 188
           F   AA    R   AA+ P LW         +G P++  V+       S  W+
Sbjct: 255 FAAVAASSAVRLTPAANAPPLW-----VPGAIGSPSQEAVRPPSNFTGSSPWM 302



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 25/65 (38%), Positives = 26/65 (40%), Gaps = 4/65 (6%)

Query: 50  SEPGPARPR-AQRRASRRTPRQPPRG--PSAAAKPKAGLRSEAAAAPAPAPA-PTPTPEE 105
           S   PA P      A+   P  P  G  P A A P AG   EA AAPA A          
Sbjct: 431 SGAAPAAPADPDSGAAPDAPADPDSGAAPDAPADPDAGAAPEAPAAPAAAETRAAHVAPA 490

Query: 106 GPDAG 110
            PDAG
Sbjct: 491 APDAG 495



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 26/78 (33%), Positives = 34/78 (43%), Gaps = 20/78 (25%)

Query: 54  PARPRA-QRRASRRTPRQP----PRGPSAAAKPKAGLRSEAAAAPA-----------PAP 97
           PA P A + RA+   P  P    P  P+A+A   A +R  A+AAPA           P+P
Sbjct: 474 PAAPAAAETRAAHVAPAAPDAGAPTAPAASATRAAQVRRAASAAPASGARRKIHLRPPSP 533

Query: 98  ----APTPTPEEGPDAGW 111
               A  PTP     + W
Sbjct: 534 EIQAADPPTPRPTRASAW 551


>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
           sapiens]
          Length = 300

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 38/125 (30%), Positives = 56/125 (44%), Gaps = 5/125 (4%)

Query: 212 LKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQH-SMVESTAVVSFLEEA 270
           L  + E CPRL  L L+ C  V   AL  LA  C  L  LDL     ++  A+V   +  
Sbjct: 132 LGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRR 191

Query: 271 GSRMRKLWLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL 330
           G+ +R L L  ++         L   CP+L  L+++  +   S      V  L + CP L
Sbjct: 192 GAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSD----GVRTLAEYCPVL 247

Query: 331 QVLRL 335
           + LR+
Sbjct: 248 RSLRV 252



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 45/135 (33%), Positives = 61/135 (45%), Gaps = 12/135 (8%)

Query: 322 ALQKGCPQLQVLRLLNLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLL- 380
           AL +GCP+LQ L L +  W+     RG+A     P+LEEL L  + C  + +E +  L  
Sbjct: 134 ALAEGCPRLQRLSLAHCDWVDGLALRGLA--DRCPALEELDL--TACRQLKDEAIVYLAQ 189

Query: 381 HGSPNLRLLDLRGCARITPAGLQDLPCRELEQLHLGLYGT----SDRLTLAKEGSPFLTQ 436
                LR L L   A +  A +Q+L     E  HL L G     SD +    E  P L  
Sbjct: 190 RRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYCPVLRS 249

Query: 437 ---KWCHTLRELDLS 448
              + CH + E  LS
Sbjct: 250 LRVRHCHHVAESSLS 264



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 16/154 (10%)

Query: 358 LEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITPAGLQDLP--CRELEQLHL 415
           L+EL LA     ++S+E L  +L  +P LR + L GC +++   L  L   C  L++L L
Sbjct: 89  LQELALAPCH-EWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSL 147

Query: 416 GLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGFSEKDLEQALAAFLSTPGGSHPAL 475
                 D L L            C  L ELDL+    + + L+     +L+   G+   L
Sbjct: 148 AHCDWVDGLALRGLADR------CPALEELDLT----ACRQLKDEAIVYLAQRRGA--GL 195

Query: 476 CSLNLR-GTRVTPSTVSSVISSCPGLLYLNLESC 508
            SL+L     V  + V  +  +CP L +L+L  C
Sbjct: 196 RSLSLAVNANVGDAAVQELARNCPELHHLDLTGC 229



 Score = 33.9 bits (76), Expect = 0.39
 Identities = 24/88 (27%), Positives = 44/88 (50%)

Query: 184 SLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAK 243
           ++ +L   R + L+ L+L    +     ++ +   CP L  L L+GC  V +D +  LA+
Sbjct: 183 AIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAE 242

Query: 244 ACCQLHSLDLQHSMVESTAVVSFLEEAG 271
            C  L SL ++H    + + +S L + G
Sbjct: 243 YCPVLRSLRVRHCHHVAESSLSRLRKRG 270


>gi|116268109 nucleotide-binding oligomerization domains 27 [Homo
            sapiens]
          Length = 1866

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 82/300 (27%), Positives = 116/300 (38%), Gaps = 59/300 (19%)

Query: 223  TFLKLSGCHGVTADALVMLAKA---CCQLHSLDLQHSMVESTAVVSFLE--EAGSRMRKL 277
            TF   S C  V+ + L  LA     C  L  LDL ++  +     + +   E    +++L
Sbjct: 1498 TFRLTSSC--VSTEGLAHLASGLGHCHHLEELDLSNNQFDEEGTKALMRALEGKWMLKRL 1555

Query: 278  WLTYSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQL-QVLRLL 336
             L++    ++ L ALL     Q+  L+ S  +NRNSI           GC  L + LR  
Sbjct: 1556 DLSHLLLNSSTL-ALLTHRLSQMTCLQ-SLRLNRNSIG--------DVGCCHLSEALRAA 1605

Query: 337  NLMWLPKPPGRGVAPGPGFPSLEELCLASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCAR 396
                                SLEEL L+ +       + L  +L G P LR +DL G + 
Sbjct: 1606 T-------------------SLEELDLSHNQIGDAGVQHLATILPGLPELRKIDLSGNSI 1646

Query: 397  ITPAGLQ----DLPCRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCHTLRELDLSGQGF 452
             +  G+Q     + CR LE+L LG     D   L       L Q+    LR L L    F
Sbjct: 1647 SSAGGVQLAESLVLCRRLEELMLGCNALGDPTALG------LAQELPQHLRVLHLP---F 1697

Query: 453  SEKDLEQALAAFLSTPGGSHPALCSL---NLRGTRVTPSTVSSVISSCPGLLYLNLESCR 509
            S      AL+   +  G  H    SL   NL G       V       P L  ++L SC+
Sbjct: 1698 SHLGPGGALSLAQALDGSPHLEEISLAENNLAG------GVLRFCMELPLLRQIDLVSCK 1751


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 73/280 (26%), Positives = 109/280 (38%), Gaps = 53/280 (18%)

Query: 14  RAAPRPRSAED-WWWDRLAPRGSGYHLLQSDSMLLVLSEPGPA----RPRAQRRASRRTP 68
           RA+PRP + ED W     +P G G      DS LL LS PGP     RP +     R + 
Sbjct: 282 RASPRPWTPEDPWSLYGPSPGGRG----PEDSWLL-LSAPGPTPASPRPASPCGKRRYSS 336

Query: 69  RQPPRGPSAAAKPKAGLRSEAAAAPAPAPAP------TPTPEEGPDAGWGDRIPLEILVQ 122
              P   S A   +  L  E +  P P P P      +P P +   A   + IP +    
Sbjct: 337 SGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRT 396

Query: 123 IFGLLVA---------ADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
                VA          +G +P LG    V      +  + A    + + SPL    A+ 
Sbjct: 397 SSEQAVALPRSEEPASCNGKLP-LGAEESVAPP-GGSRKEVAGMDYLAVPSPLAWSKARI 454

Query: 174 GVKA---EKKLLASLEWLMPNRFSQLQ-RLTL-------IHWKSQ-----------VHPV 211
           G  +       L  L+W +P+++ QL+ R+ +        H++++            HPV
Sbjct: 455 GGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPV 514

Query: 212 LKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSL 251
           +KL+G     LT     G    TAD   +   A  Q+H +
Sbjct: 515 VKLLGYSEKPLTLQMFIG----TADERNLRPHAFYQVHRI 550


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 73/280 (26%), Positives = 109/280 (38%), Gaps = 53/280 (18%)

Query: 14  RAAPRPRSAED-WWWDRLAPRGSGYHLLQSDSMLLVLSEPGPA----RPRAQRRASRRTP 68
           RA+PRP + ED W     +P G G      DS LL LS PGP     RP +     R + 
Sbjct: 219 RASPRPWTPEDPWSLYGPSPGGRG----PEDSWLL-LSAPGPTPASPRPASPCGKRRYSS 273

Query: 69  RQPPRGPSAAAKPKAGLRSEAAAAPAPAPAP------TPTPEEGPDAGWGDRIPLEILVQ 122
              P   S A   +  L  E +  P P P P      +P P +   A   + IP +    
Sbjct: 274 SGTPSSASPALSRRGSLGEEGSEPPPPPPLPLARDPGSPGPFDYVGAPPAESIPQKTRRT 333

Query: 123 IFGLLVA---------ADGPMPFLGRAARVCRRWQEAASQPALWHTVTLSSPLVGRPAKG 173
                VA          +G +P LG    V      +  + A    + + SPL    A+ 
Sbjct: 334 SSEQAVALPRSEEPASCNGKLP-LGAEESVAPP-GGSRKEVAGMDYLAVPSPLAWSKARI 391

Query: 174 GVKA---EKKLLASLEWLMPNRFSQLQ-RLTL-------IHWKSQ-----------VHPV 211
           G  +       L  L+W +P+++ QL+ R+ +        H++++            HPV
Sbjct: 392 GGHSPIFRTSALPPLDWPLPSQYEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPV 451

Query: 212 LKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSL 251
           +KL+G     LT     G    TAD   +   A  Q+H +
Sbjct: 452 VKLLGYSEKPLTLQMFIG----TADERNLRPHAFYQVHRI 487


>gi|24308207 leucine rich repeat containing 47 [Homo sapiens]
          Length = 583

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 48/175 (27%), Positives = 67/175 (38%), Gaps = 29/175 (16%)

Query: 328 PQLQVLRLLNLMWLPKPPGRGVAPG--PGFPSLEELCLASSTCNFVSNEVLGRLLHGSPN 385
           P L+VL L        PPG+G+ P   PG P L+ L L+ +       E+   L   +P 
Sbjct: 99  PALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRL----RELPADLARCAPR 154

Query: 386 LRLLDLRG-CARITPAGLQDLPCRELEQLHLGLYGTSDRLTLAKEGSPFLTQKWCH--TL 442
           L+ L+L G C    PA          E    G       L  A      L+    H  +L
Sbjct: 155 LQSLNLTGNCLDSFPA----------ELFRPGALPLLSELAAADNCLRELSPDIAHLASL 204

Query: 443 RELDLSGQGFSEKDLEQALAAFLSTPGGSHPALCSLNLRGTRVTPSTVSSVISSC 497
           + LDLS    SE   E A            P L  +N RG ++    +  ++S C
Sbjct: 205 KTLDLSNNQLSEIPAELA----------DCPKLKEINFRGNKLRDKRLEKMVSGC 249


>gi|157168349 F-box and leucine-rich repeat protein 19 [Homo
           sapiens]
          Length = 694

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 94/360 (26%), Positives = 135/360 (37%), Gaps = 81/360 (22%)

Query: 48  VLSEP-GPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEG 106
           +LS P GPA P    +  R   R PPR P            E    P  A +  P P   
Sbjct: 381 LLSWPLGPAPPPRPPQLERHVVRPPPRSP------------EPDTLPLAAGSDHPLPR-- 426

Query: 107 PDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVTLS-SP 165
             A W         +++F  L    GP   L    RVCR W        LW  + LS   
Sbjct: 427 --AAW---------LRVFQHL----GPRE-LCICMRVCRTWSRWCYDKRLWPRMDLSRRK 470

Query: 166 LVGRPAKGGVKAEKKLLASLEWLMPNRFSQLQRLTLIHWKSQVHPVLKLVGECCPRLTFL 225
            +  P   GV   +     L W      S+ Q + L++         +L G     L  L
Sbjct: 471 SLTPPMLSGVVRRQPRALDLSW---TGVSKKQLMWLLN---------RLQG-----LQEL 513

Query: 226 KLSGCHGVTADALVMLAKACCQLHSLDLQHSMVESTAVVSFLEEA-GSRMRKLWL----T 280
            LSGC  ++  AL        +L  LDL+           ++E+   S++R+L L    T
Sbjct: 514 VLSGCSWLSVSALGSAPLPALRL--LDLR-----------WIEDVKDSQLRELLLPPPDT 560

Query: 281 YSSQTTAILGALLGSCCPQLQVLEVSTGINRNSIPLQLPVEALQKGCPQLQVLRLLNLMW 340
              QT +  G L G    +L  LE++             +  L +  PQL  L L +   
Sbjct: 561 KPGQTES-RGRLQGVAELRLAGLELT----------DASLRLLLRHAPQLSALDLSHCAH 609

Query: 341 LPKPPGRGVAPGPGFPSLEELC-LASSTCNFVSNEVLGRLLHGSPNLRLLDLRGCARITP 399
           +  P    +   P  P  E L  L  + C+ +++  L  L    P LR LDLR C +++P
Sbjct: 610 VGDPSVH-LLTAPTSPLRETLVHLNLAGCHRLTDHCL-PLFRRCPRLRRLDLRSCRQLSP 667


>gi|239750101 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 365

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 27/60 (45%), Positives = 29/60 (48%), Gaps = 8/60 (13%)

Query: 51  EPGPARPRAQRR---ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGP 107
           EP PA PRA  R   A+RR P  PP  P A A+P  G RS     PA  P   PT    P
Sbjct: 306 EPRPAEPRAPPRPPPAARRPP--PPPAPGAPARPLRGRRSH---GPAARPRAVPTTSLAP 360


>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
          Length = 515

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 2/70 (2%)

Query: 45  MLLVLSEPGPAR--PRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPT 102
           M+L   EP  AR    AQ      T   PP GP  +  P+A +         PA A    
Sbjct: 1   MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHE 60

Query: 103 PEEGPDAGWG 112
           P E P+ GWG
Sbjct: 61  PPEPPEGGWG 70


>gi|30520327 F-box protein 27 [Homo sapiens]
          Length = 283

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 7/64 (10%)

Query: 94  APAPAPTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQ 153
           A  PAP P PEE  D     ++P E+L+ +   +     P   LGR  +VCR W+     
Sbjct: 11  ARVPAPEPEPEEALDLS---QLPPELLLVVLSHVP----PRTLLGRCRQVCRGWRALVDG 63

Query: 154 PALW 157
            ALW
Sbjct: 64  QALW 67


>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 175

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 22/59 (37%), Positives = 25/59 (42%)

Query: 52  PGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAG 110
           PG A   A  R + R P  PP  P     P AGL    A +  P+PAP P     P  G
Sbjct: 114 PGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172


>gi|4505101 microtubule-associated protein 7 [Homo sapiens]
          Length = 749

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 21/45 (46%), Positives = 26/45 (57%), Gaps = 1/45 (2%)

Query: 66  RTPRQPPRGPSAAAKPKAGLRSEA-AAAPAPAPAPTPTPEEGPDA 109
           RTP +P  GP+A A   A   + A A+APAPAP PTP     P +
Sbjct: 415 RTPAEPEVGPAAPAMAPAPASAPAPASAPAPAPVPTPAMVSAPSS 459


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 37/115 (32%), Positives = 40/115 (34%), Gaps = 23/115 (20%)

Query: 15  AAPRPRSAEDWWWDRLAPRGSGYHLLQSDSMLLVLSEPGPARPRAQRR------------ 62
           AAP P  A      R  P G G       S    L   GPA P A+ R            
Sbjct: 85  AAPEPPPA-----GRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAP 139

Query: 63  -----ASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDAGWG 112
                A    P   P GP+  A P A L + A   P P P P P P  G  AG G
Sbjct: 140 VPAAAAVAAGPEPAPAGPAKPAGP-AALAARAGPGPGPGPGPGPGPGPGKPAGPG 193



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 36/124 (29%), Positives = 44/124 (35%), Gaps = 7/124 (5%)

Query: 48  VLSEPGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAP---APAPTPTP- 103
           +L  P PA P    +         P  P+A + P A   +  AAAP P   APA    P 
Sbjct: 225 LLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP 284

Query: 104 --EEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALWHTVT 161
               GP       +P     Q  G   AA  P P  G  A V  +    A+  A    V 
Sbjct: 285 GHPAGPPTA-APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343

Query: 162 LSSP 165
             SP
Sbjct: 344 AESP 347


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 20/41 (48%), Positives = 22/41 (53%), Gaps = 1/41 (2%)

Query: 68  PRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPD 108
           P  PP  PS  A P A +  E  A PAP PA  PTPE  P+
Sbjct: 508 PAAPPAAPSTPAPPPA-VPKELPAPPAPPPASAPTPETEPE 547



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 19/63 (30%), Positives = 21/63 (33%), Gaps = 1/63 (1%)

Query: 50  SEPGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAPTPTPEEGPDA 109
           S  G  RP         +P   P  P  A    +         PAP P P P P  GP  
Sbjct: 363 SASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKP-PLPPPHRGPAG 421

Query: 110 GWG 112
            WG
Sbjct: 422 NWG 424



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 27/85 (31%), Positives = 33/85 (38%), Gaps = 15/85 (17%)

Query: 49  LSEPGPAR----PRAQRRASRRTP---RQPPR-------GPSAAAKPKAGLRSEAAAAPA 94
           L EPGP      P +   A  +TP   ++PP+       GP A  KP  G+ S     P 
Sbjct: 856 LEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPP 915

Query: 95  PAPAPTPTPEEGPDAGWGDR-IPLE 118
           P          GP  G   R IP E
Sbjct: 916 PRRESRTETRWGPRPGSSRRGIPPE 940


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 23/68 (33%), Positives = 28/68 (41%)

Query: 40   LQSDSMLLVLSEPGPARPRAQRRASRRTPRQPPRGPSAAAKPKAGLRSEAAAAPAPAPAP 99
            L + S  L    PGP +P     A    P   P GP AA     G  S   + P+P   P
Sbjct: 1027 LPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVP 1086

Query: 100  TPTPEEGP 107
            +P P  GP
Sbjct: 1087 SPAPSPGP 1094


>gi|30089926 F-box only protein 11 isoform 1 [Homo sapiens]
          Length = 843

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 17/120 (14%)

Query: 47  LVLSEPGPARPRAQRRASRRT---------PRQPPRGPSAAAKPKAGLRSEAAAAPAPAP 97
           +V  E GP    +  +  R+T          +    G S +     G R++ A     + 
Sbjct: 1   MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60

Query: 98  APTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW 157
             +  P E       +++P E++++IF  L+  D     L RAA VC+R+ E A+ P LW
Sbjct: 61  DLSAAPAE---QYLQEKLPDEVVLKIFSYLLEQD-----LCRAACVCKRFSELANDPILW 112


>gi|30089924 F-box only protein 11 isoform 2 [Homo sapiens]
          Length = 686

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 17/120 (14%)

Query: 47  LVLSEPGPARPRAQRRASRRT---------PRQPPRGPSAAAKPKAGLRSEAAAAPAPAP 97
           +V  E GP    +  +  R+T          +    G S +     G R++ A     + 
Sbjct: 1   MVAEESGPGAQNSPYQLRRKTLLPKRTACPTKNSMEGASTSTTENFGHRAKRARVSGKSQ 60

Query: 98  APTPTPEEGPDAGWGDRIPLEILVQIFGLLVAADGPMPFLGRAARVCRRWQEAASQPALW 157
             +  P E       +++P E++++IF  L+  D     L RAA VC+R+ E A+ P LW
Sbjct: 61  DLSAAPAE---QYLQEKLPDEVVLKIFSYLLEQD-----LCRAACVCKRFSELANDPILW 112


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,743,815
Number of Sequences: 37866
Number of extensions: 1414369
Number of successful extensions: 15218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 187
Number of HSP's successfully gapped in prelim test: 534
Number of HSP's that attempted gapping in prelim test: 11601
Number of HSP's gapped (non-prelim): 3301
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.