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Search of human proteins with 162287219
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|162287219 prune homolog 2 [Homo sapiens]
(3088 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|162287219 prune homolog 2 [Homo sapiens] 6254 0.0
gi|29336043 caytaxin [Homo sapiens] 381 e-105
gi|168480080 BCL2/adenovirus E1B 19kD interacting protein 2 [Hom... 342 3e-93
gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like i... 251 8e-66
gi|228008343 BCL2/adenovirus E1B 19kD interacting protein like i... 245 6e-64
gi|24308263 prune [Homo sapiens] 212 4e-54
gi|4757766 Rho GTPase activating protein 1 [Homo sapiens] 111 1e-23
gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens] 105 9e-22
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 105 9e-22
gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapi... 105 9e-22
gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapi... 90 3e-17
gi|207450721 ganglioside induced differentiation associated prot... 60 3e-08
gi|8923143 ganglioside induced differentiation associated protei... 57 4e-07
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 52 1e-05
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 51 2e-05
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 47 4e-04
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 46 7e-04
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 45 0.001
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi... 44 0.002
gi|150170670 piccolo isoform 2 [Homo sapiens] 44 0.002
gi|150378539 piccolo isoform 1 [Homo sapiens] 44 0.002
gi|111607441 hypothetical protein LOC400506 [Homo sapiens] 44 0.003
gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens] 42 0.009
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 42 0.012
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 41 0.021
gi|16445033 ACRC protein [Homo sapiens] 40 0.027
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 40 0.036
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] 40 0.036
gi|63176611 modulator of estrogen induced transcription isoform ... 40 0.036
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 40 0.036
>gi|162287219 prune homolog 2 [Homo sapiens]
Length = 3088
Score = 6254 bits (16225), Expect = 0.0
Identities = 3088/3088 (100%), Positives = 3088/3088 (100%)
Query: 1 MEEFLQRAKSKLNRSKRLEKVHVVIGPKSCDLDSLISTFTYAYFLDKVSPPGVLCLPVLN 60
MEEFLQRAKSKLNRSKRLEKVHVVIGPKSCDLDSLISTFTYAYFLDKVSPPGVLCLPVLN
Sbjct: 1 MEEFLQRAKSKLNRSKRLEKVHVVIGPKSCDLDSLISTFTYAYFLDKVSPPGVLCLPVLN 60
Query: 61 IPRTEFNYFTETRFILEELNISESFHIFRDEINLHQLNDEGKLSITLVGSSVLASEDKTL 120
IPRTEFNYFTETRFILEELNISESFHIFRDEINLHQLNDEGKLSITLVGSSVLASEDKTL
Sbjct: 61 IPRTEFNYFTETRFILEELNISESFHIFRDEINLHQLNDEGKLSITLVGSSVLASEDKTL 120
Query: 121 ESAVVKVINPVEQSDANVEFRESSSSLVLKEILQEAPELITEQLAHRLRGSILFKWMTME 180
ESAVVKVINPVEQSDANVEFRESSSSLVLKEILQEAPELITEQLAHRLRGSILFKWMTME
Sbjct: 121 ESAVVKVINPVEQSDANVEFRESSSSLVLKEILQEAPELITEQLAHRLRGSILFKWMTME 180
Query: 181 SEKISEKQEEILSILEEKFPNLPPREDIINVLQETQFSAQGLSIEQTMLKDLKELSDGEI 240
SEKISEKQEEILSILEEKFPNLPPREDIINVLQETQFSAQGLSIEQTMLKDLKELSDGEI
Sbjct: 181 SEKISEKQEEILSILEEKFPNLPPREDIINVLQETQFSAQGLSIEQTMLKDLKELSDGEI 240
Query: 241 KVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFSSYLSEEQQPRRQIAVYSENM 300
KVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFSSYLSEEQQPRRQIAVYSENM
Sbjct: 241 KVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFSSYLSEEQQPRRQIAVYSENM 300
Query: 301 ELCSQICCELEECQNPCLELEPFDCGCDEILVYQQEDPSVTCDQVVLVVKEVINRRCPEM 360
ELCSQICCELEECQNPCLELEPFDCGCDEILVYQQEDPSVTCDQVVLVVKEVINRRCPEM
Sbjct: 301 ELCSQICCELEECQNPCLELEPFDCGCDEILVYQQEDPSVTCDQVVLVVKEVINRRCPEM 360
Query: 361 VSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPDLNDSNQAQVDAN 420
VSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPDLNDSNQAQVDAN
Sbjct: 361 VSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPDLNDSNQAQVDAN 420
Query: 421 VDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAVAEE 480
VDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAVAEE
Sbjct: 421 VDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAVAEE 480
Query: 481 HAWSGEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDFFPNSDLSEGQLPAGPEGLD 540
HAWSGEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDFFPNSDLSEGQLPAGPEGLD
Sbjct: 481 HAWSGEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDFFPNSDLSEGQLPAGPEGLD 540
Query: 541 GMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSPER 600
GMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSPER
Sbjct: 541 GMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSPER 600
Query: 601 LKNTGKRIPPTPMNSLVESSPSTEEPASLYTEDMTQKATDTGHMGPPQTHARCSSWWGGL 660
LKNTGKRIPPTPMNSLVESSPSTEEPASLYTEDMTQKATDTGHMGPPQTHARCSSWWGGL
Sbjct: 601 LKNTGKRIPPTPMNSLVESSPSTEEPASLYTEDMTQKATDTGHMGPPQTHARCSSWWGGL 660
Query: 661 EIDSKNIADAWSSSEQESVFQSPESWKEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEF 720
EIDSKNIADAWSSSEQESVFQSPESWKEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEF
Sbjct: 661 EIDSKNIADAWSSSEQESVFQSPESWKEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEF 720
Query: 721 GQPELGSNDIQDKNEESLPFQNLPMEKSPLPNTSPQGTNHLIEDFASLWHSGRSPTAMPE 780
GQPELGSNDIQDKNEESLPFQNLPMEKSPLPNTSPQGTNHLIEDFASLWHSGRSPTAMPE
Sbjct: 721 GQPELGSNDIQDKNEESLPFQNLPMEKSPLPNTSPQGTNHLIEDFASLWHSGRSPTAMPE 780
Query: 781 PWGNPTDDGEPAAVAPFPAWSAFGKEDHDEALKNTWNLHPTSSKTPSVRDPNEWAMAKSG 840
PWGNPTDDGEPAAVAPFPAWSAFGKEDHDEALKNTWNLHPTSSKTPSVRDPNEWAMAKSG
Sbjct: 781 PWGNPTDDGEPAAVAPFPAWSAFGKEDHDEALKNTWNLHPTSSKTPSVRDPNEWAMAKSG 840
Query: 841 FAFSSSELLDNSPSEINNEAAPEIWGKKNNDSRDHIFAPGNPSSDLDHTWTNSKPPKEDQ 900
FAFSSSELLDNSPSEINNEAAPEIWGKKNNDSRDHIFAPGNPSSDLDHTWTNSKPPKEDQ
Sbjct: 841 FAFSSSELLDNSPSEINNEAAPEIWGKKNNDSRDHIFAPGNPSSDLDHTWTNSKPPKEDQ 900
Query: 901 NGLVDPKTRGKVYEKVDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVP 960
NGLVDPKTRGKVYEKVDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVP
Sbjct: 901 NGLVDPKTRGKVYEKVDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVP 960
Query: 961 SPLDTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSR 1020
SPLDTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSR
Sbjct: 961 SPLDTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSR 1020
Query: 1021 NRISSGPGNLDMWASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYD 1080
NRISSGPGNLDMWASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYD
Sbjct: 1021 NRISSGPGNLDMWASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYD 1080
Query: 1081 DPSMMQLYNETNRQLTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDD 1140
DPSMMQLYNETNRQLTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDD
Sbjct: 1081 DPSMMQLYNETNRQLTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDD 1140
Query: 1141 CSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSA 1200
CSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSA
Sbjct: 1141 CSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSA 1200
Query: 1201 PSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVK 1260
PSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVK
Sbjct: 1201 PSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVK 1260
Query: 1261 DTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHG 1320
DTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHG
Sbjct: 1261 DTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHG 1320
Query: 1321 DGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEICIKS 1380
DGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEICIKS
Sbjct: 1321 DGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEICIKS 1380
Query: 1381 GKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEKHLMSQRNS 1440
GKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEKHLMSQRNS
Sbjct: 1381 GKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEKHLMSQRNS 1440
Query: 1441 GETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRVPRSLDFGDVPIDSDV 1500
GETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRVPRSLDFGDVPIDSDV
Sbjct: 1441 GETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRVPRSLDFGDVPIDSDV 1500
Query: 1501 HVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSSASSPELNDSSVALSSW 1560
HVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSSASSPELNDSSVALSSW
Sbjct: 1501 HVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSSASSPELNDSSVALSSW 1560
Query: 1561 GQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRINEFEKSFDRKTPT 1620
GQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRINEFEKSFDRKTPT
Sbjct: 1561 GQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRINEFEKSFDRKTPT 1620
Query: 1621 FLEIWNDSVDGDSFSSLSSPETGKYSEHSGTHQESNLIASYQEKNEHDISATVQPEDARV 1680
FLEIWNDSVDGDSFSSLSSPETGKYSEHSGTHQESNLIASYQEKNEHDISATVQPEDARV
Sbjct: 1621 FLEIWNDSVDGDSFSSLSSPETGKYSEHSGTHQESNLIASYQEKNEHDISATVQPEDARV 1680
Query: 1681 ISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPKSENIYDY 1740
ISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPKSENIYDY
Sbjct: 1681 ISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPKSENIYDY 1740
Query: 1741 LDSSEPAENENKSNPFCDNQQSSPDPWTFSPLTETEMQITAVEKEKRSSPETGTTGDVAW 1800
LDSSEPAENENKSNPFCDNQQSSPDPWTFSPLTETEMQITAVEKEKRSSPETGTTGDVAW
Sbjct: 1741 LDSSEPAENENKSNPFCDNQQSSPDPWTFSPLTETEMQITAVEKEKRSSPETGTTGDVAW 1800
Query: 1801 QISPKASFPKNEDNSQLEMLGFSADSTEWWKASPQEGRLIESPFERELSDSSGVLEINSS 1860
QISPKASFPKNEDNSQLEMLGFSADSTEWWKASPQEGRLIESPFERELSDSSGVLEINSS
Sbjct: 1801 QISPKASFPKNEDNSQLEMLGFSADSTEWWKASPQEGRLIESPFERELSDSSGVLEINSS 1860
Query: 1861 VHQNASPWGVPVQGDIEPVETHYTNPFSDNHQSPFLEGNGKNSHEQLWNIQPRQPDPDAD 1920
VHQNASPWGVPVQGDIEPVETHYTNPFSDNHQSPFLEGNGKNSHEQLWNIQPRQPDPDAD
Sbjct: 1861 VHQNASPWGVPVQGDIEPVETHYTNPFSDNHQSPFLEGNGKNSHEQLWNIQPRQPDPDAD 1920
Query: 1921 KFSQLVKLDQIKEKDSREQTFVSAAGDELTPETPTQEQCQDTMLPVCDHPDTAFTHAEEN 1980
KFSQLVKLDQIKEKDSREQTFVSAAGDELTPETPTQEQCQDTMLPVCDHPDTAFTHAEEN
Sbjct: 1921 KFSQLVKLDQIKEKDSREQTFVSAAGDELTPETPTQEQCQDTMLPVCDHPDTAFTHAEEN 1980
Query: 1981 SCVTSNVSTNEGQETNQWEQEKSYLGEMTNSSIATENFPAVSSPTQLIMKPGSEWDGSTP 2040
SCVTSNVSTNEGQETNQWEQEKSYLGEMTNSSIATENFPAVSSPTQLIMKPGSEWDGSTP
Sbjct: 1981 SCVTSNVSTNEGQETNQWEQEKSYLGEMTNSSIATENFPAVSSPTQLIMKPGSEWDGSTP 2040
Query: 2041 SEDSRGTFVPDILHGNFQEGGQLASAAPDLWIDAKKPFSLKADGENPDILTHCEHDSNSQ 2100
SEDSRGTFVPDILHGNFQEGGQLASAAPDLWIDAKKPFSLKADGENPDILTHCEHDSNSQ
Sbjct: 2041 SEDSRGTFVPDILHGNFQEGGQLASAAPDLWIDAKKPFSLKADGENPDILTHCEHDSNSQ 2100
Query: 2101 ASDSPDICHDSEAKQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGREFVPSNAEL 2160
ASDSPDICHDSEAKQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGREFVPSNAEL
Sbjct: 2101 ASDSPDICHDSEAKQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGREFVPSNAEL 2160
Query: 2161 DSENATVLPPIGYQADIKGSSQPASHKGSPEPSEINGDNSTGLQVSEKGASPDMAPILEP 2220
DSENATVLPPIGYQADIKGSSQPASHKGSPEPSEINGDNSTGLQVSEKGASPDMAPILEP
Sbjct: 2161 DSENATVLPPIGYQADIKGSSQPASHKGSPEPSEINGDNSTGLQVSEKGASPDMAPILEP 2220
Query: 2221 VDRRIPRIENVATSIFVTHQEPTPEGDGSWISDSFSPESQPGARALFDGDPHLSTENPAL 2280
VDRRIPRIENVATSIFVTHQEPTPEGDGSWISDSFSPESQPGARALFDGDPHLSTENPAL
Sbjct: 2221 VDRRIPRIENVATSIFVTHQEPTPEGDGSWISDSFSPESQPGARALFDGDPHLSTENPAL 2280
Query: 2281 VPDALLASDTCLDISEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDLGKQ 2340
VPDALLASDTCLDISEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDLGKQ
Sbjct: 2281 VPDALLASDTCLDISEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDLGKQ 2340
Query: 2341 DICSSEASWGDFEYDVMGQNIDEDLLREPEHFLYGGDPPLEEDSLKQSLAPYTPPFDLSY 2400
DICSSEASWGDFEYDVMGQNIDEDLLREPEHFLYGGDPPLEEDSLKQSLAPYTPPFDLSY
Sbjct: 2341 DICSSEASWGDFEYDVMGQNIDEDLLREPEHFLYGGDPPLEEDSLKQSLAPYTPPFDLSY 2400
Query: 2401 LTEPAQSAETIEEAGSPEDESLGCRAAEIVLSALPDRRSEGNQAETKNRLPGSQLAVLHI 2460
LTEPAQSAETIEEAGSPEDESLGCRAAEIVLSALPDRRSEGNQAETKNRLPGSQLAVLHI
Sbjct: 2401 LTEPAQSAETIEEAGSPEDESLGCRAAEIVLSALPDRRSEGNQAETKNRLPGSQLAVLHI 2460
Query: 2461 REDPESVYLPVGAGSNILSPSNVDWEVETDNSDLPAGGDIGPPNGASKEISELEEEKTIP 2520
REDPESVYLPVGAGSNILSPSNVDWEVETDNSDLPAGGDIGPPNGASKEISELEEEKTIP
Sbjct: 2461 REDPESVYLPVGAGSNILSPSNVDWEVETDNSDLPAGGDIGPPNGASKEISELEEEKTIP 2520
Query: 2521 TKEPEQIKSEYKEERCTEKNEDRHALHMDYILVNREENSHSKPETCEERESIAELELYVG 2580
TKEPEQIKSEYKEERCTEKNEDRHALHMDYILVNREENSHSKPETCEERESIAELELYVG
Sbjct: 2521 TKEPEQIKSEYKEERCTEKNEDRHALHMDYILVNREENSHSKPETCEERESIAELELYVG 2580
Query: 2581 SKETGLQGTQLASFPDTCQPASLNERKGLSAEKMSSKSDTRSSFESPAQDQSWMFLGHSE 2640
SKETGLQGTQLASFPDTCQPASLNERKGLSAEKMSSKSDTRSSFESPAQDQSWMFLGHSE
Sbjct: 2581 SKETGLQGTQLASFPDTCQPASLNERKGLSAEKMSSKSDTRSSFESPAQDQSWMFLGHSE 2640
Query: 2641 VGDPSLDARDSGPGWSGKTVEPFSELGLGEGPQLQILEEMKPLESLALEEASGPVSQSQK 2700
VGDPSLDARDSGPGWSGKTVEPFSELGLGEGPQLQILEEMKPLESLALEEASGPVSQSQK
Sbjct: 2641 VGDPSLDARDSGPGWSGKTVEPFSELGLGEGPQLQILEEMKPLESLALEEASGPVSQSQK 2700
Query: 2701 SKSRGRAGPDAVTLQAVTHDNEWEMLSPQPVQKNMIPDTEMEEETEFLELGTRISRPNGL 2760
SKSRGRAGPDAVTLQAVTHDNEWEMLSPQPVQKNMIPDTEMEEETEFLELGTRISRPNGL
Sbjct: 2701 SKSRGRAGPDAVTLQAVTHDNEWEMLSPQPVQKNMIPDTEMEEETEFLELGTRISRPNGL 2760
Query: 2761 LSEDVGMDIPFEEGVLSPSAADMRPEPPNSLDLNDTHPRRIKLTAPNINLSLDQSEGSIL 2820
LSEDVGMDIPFEEGVLSPSAADMRPEPPNSLDLNDTHPRRIKLTAPNINLSLDQSEGSIL
Sbjct: 2761 LSEDVGMDIPFEEGVLSPSAADMRPEPPNSLDLNDTHPRRIKLTAPNINLSLDQSEGSIL 2820
Query: 2821 SDDNLDSPDEIDINVDELDTPDEADSFEYTGHDPTANKDSGQESESIPEYTAEEEREDNR 2880
SDDNLDSPDEIDINVDELDTPDEADSFEYTGHDPTANKDSGQESESIPEYTAEEEREDNR
Sbjct: 2821 SDDNLDSPDEIDINVDELDTPDEADSFEYTGHDPTANKDSGQESESIPEYTAEEEREDNR 2880
Query: 2881 LWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVME 2940
LWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVME
Sbjct: 2881 LWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVME 2940
Query: 2941 NLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVH 3000
NLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVH
Sbjct: 2941 NLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVH 3000
Query: 3001 PSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREASE 3060
PSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREASE
Sbjct: 3001 PSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREASE 3060
Query: 3061 AAKTSCLYNDPEMSSMEKDIDLKLKEKP 3088
AAKTSCLYNDPEMSSMEKDIDLKLKEKP
Sbjct: 3061 AAKTSCLYNDPEMSSMEKDIDLKLKEKP 3088
>gi|29336043 caytaxin [Homo sapiens]
Length = 371
Score = 381 bits (979), Expect = e-105
Identities = 191/315 (60%), Positives = 240/315 (76%), Gaps = 14/315 (4%)
Query: 2763 EDVGMDIPFEEGV-LSPSAADMRPEPPNSLDLNDTHPRRIKLTAPNINLSLDQSEGSILS 2821
ED+ +P E GV L S + PPN+L+ N H +R L AP IN+SLDQSEGS+LS
Sbjct: 22 EDLPRPLPEETGVELLGSPVEDTSSPPNTLNFNGAHRKRKTLVAPEINISLDQSEGSLLS 81
Query: 2822 DDNLDSPDEIDINVDELDTPDEADSFEYTGHD-----------PTANKDSGQESESIPEY 2870
DD LD+PD++DINVD+++TPDE DS E+ G+ TA G ++ +
Sbjct: 82 DDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDG 141
Query: 2871 TAEEEREDN-RLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPD 2929
T E+ N RLWRTV+IGEQE RID+ +I PY +V++HGGYYG+GLNAIIVFAACFLPD
Sbjct: 142 TTEDGSAANGRLWRTVIIGEQEHRIDLHMIRPYMKVVTHGGYYGEGLNAIIVFAACFLPD 201
Query: 2930 SSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRL 2989
SS DYHY+MENLFLYVIS+LEL+VAEDYMIVYLNGATPRRRMPG+GW+KKCYQMIDRRL
Sbjct: 202 SSLPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRL 261
Query: 2990 RKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESII 3049
RKNLKS IIVHPSWFIRT+LA++RPFIS KF +KI+YV+SL +L LIPM+ + IP+ ++
Sbjct: 262 RKNLKSLIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVL 321
Query: 3050 KLDEE-LREASEAAK 3063
+ +EE L+ E+A+
Sbjct: 322 QYEEERLKARRESAR 336
>gi|168480080 BCL2/adenovirus E1B 19kD interacting protein 2 [Homo
sapiens]
Length = 435
Score = 342 bits (878), Expect = 3e-93
Identities = 178/303 (58%), Positives = 225/303 (74%), Gaps = 6/303 (1%)
Query: 2763 EDVGMDIPFEEGVLSPSAADMRPEP-PNSLDLNDTHPRRIKLTAPNINLSLDQSEGSILS 2821
ED + +P ++ + + A PE P SL++N R+ KL AP+I+L+LD S+GS+LS
Sbjct: 134 EDFPIPLPEDDSIEADILAITGPEDQPGSLEVNGNKVRK-KLMAPDISLTLDPSDGSVLS 192
Query: 2822 DDNLDSPDEIDINVDELDTPDE-ADSFEYTGHDPTANKDSGQESESIPEYTAEEEREDNR 2880
DD LD EID+ D LDTP E ++ FE+ P SI EYTA EE+ED R
Sbjct: 193 DD-LDESGEIDL--DGLDTPSENSNEFEWEDDLPKPKTTEVIRKGSITEYTAAEEKEDGR 249
Query: 2881 LWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVME 2940
WR IGEQ+ R+DMK IEPY++VISHGGYYGDGLNAI+VFA CF+P+SS+ +Y Y+M+
Sbjct: 250 RWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMPESSQPNYRYLMD 309
Query: 2941 NLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVH 3000
NLF YVI TLEL+VAE+YMIVYLNGAT RR+MP LGW++KCYQ IDRRLRKNLKS IIVH
Sbjct: 310 NLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVH 369
Query: 3001 PSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREASE 3060
PSWFIRT+LAVTRPFISSKFS KI+YV +L+EL+ L+PM+ + IPE I ++D+EL +
Sbjct: 370 PSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQVDQELNGKQD 429
Query: 3061 AAK 3063
K
Sbjct: 430 EPK 432
>gi|109715844 BCL2/adenovirus E1B 19kD interacting protein like
isoform a [Homo sapiens]
Length = 357
Score = 251 bits (641), Expect = 8e-66
Identities = 124/281 (44%), Positives = 194/281 (69%), Gaps = 14/281 (4%)
Query: 2788 PNSLDLNDTHPRRIKLTAPNINLSLDQ---SEGSILSDDNLDSPD-EIDINVDELDTPDE 2843
P++L L P R +L+AP + LSL + ++G+ + SPD D+ +DEL+TP +
Sbjct: 72 PSTLALCGQRPMRKRLSAPELRLSLTKGPGNDGASPTQSAPSSPDGSSDLEIDELETPSD 131
Query: 2844 ADSFEYTGHDPTANKDSGQESESIPEYTAEE---------EREDNRLWRTVVIGEQEQRI 2894
++ + +GH+ + + TAE ED WR +G +EQR+
Sbjct: 132 SEQLD-SGHEFEWEDELPRAEGLGTSETAERLGRGCMWDVTGEDGHHWRVFRMGPREQRV 190
Query: 2895 DMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMV 2954
DM VIEPY++V+SHGGY+GDGLNA+I+FA+C+LP SS +Y YVME+LF Y++ TLEL+V
Sbjct: 191 DMTVIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELLV 250
Query: 2955 AEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRP 3014
AE+Y++V+L+G T R ++P L W+++CY+ +DRRLRKNL++ ++VH +W+++ LA+ RP
Sbjct: 251 AENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLALLRP 310
Query: 3015 FISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEEL 3055
FISSKF+ KI++++SL EL+ LI +D +HIPE++ +LD +L
Sbjct: 311 FISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQLDRDL 351
>gi|228008343 BCL2/adenovirus E1B 19kD interacting protein like
isoform b [Homo sapiens]
Length = 275
Score = 245 bits (625), Expect = 6e-64
Identities = 120/269 (44%), Positives = 188/269 (69%), Gaps = 14/269 (5%)
Query: 2800 RIKLTAPNINLSLDQ---SEGSILSDDNLDSPD-EIDINVDELDTPDEADSFEYTGHDPT 2855
R +L+AP + LSL + ++G+ + SPD D+ +DEL+TP +++ + +GH+
Sbjct: 2 RKRLSAPELRLSLTKGPGNDGASPTQSAPSSPDGSSDLEIDELETPSDSEQLD-SGHEFE 60
Query: 2856 ANKDSGQESESIPEYTAEE---------EREDNRLWRTVVIGEQEQRIDMKVIEPYRRVI 2906
+ + TAE ED WR +G +EQR+DM VIEPY++V+
Sbjct: 61 WEDELPRAEGLGTSETAERLGRGCMWDVTGEDGHHWRVFRMGPREQRVDMTVIEPYKKVL 120
Query: 2907 SHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGA 2966
SHGGY+GDGLNA+I+FA+C+LP SS +Y YVME+LF Y++ TLEL+VAE+Y++V+L+G
Sbjct: 121 SHGGYHGDGLNAVILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGG 180
Query: 2967 TPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKY 3026
T R ++P L W+++CY+ +DRRLRKNL++ ++VH +W+++ LA+ RPFISSKF+ KI++
Sbjct: 181 TSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRF 240
Query: 3027 VNSLSELSGLIPMDCIHIPESIIKLDEEL 3055
++SL EL+ LI +D +HIPE++ +LD +L
Sbjct: 241 LDSLGELAQLISLDQVHIPEAVRQLDRDL 269
>gi|24308263 prune [Homo sapiens]
Length = 453
Score = 212 bits (540), Expect = 4e-54
Identities = 136/409 (33%), Positives = 222/409 (54%), Gaps = 15/409 (3%)
Query: 1 MEEFLQRAKSKLNRSKRLEKVHVVIGPKSCDLDSLISTFTYAYFLDKVSPPGVLCLPVLN 60
ME++LQ ++ L S+ L HVV+G ++CDLDS +S A++L K + + +PVLN
Sbjct: 1 MEDYLQGCRAALQESRPL---HVVLGNEACDLDSTVSALALAFYLAKTTEAEEVFVPVLN 57
Query: 61 IPRTEFNYFTETRFILEELNISESFHIFRDEINLHQLNDEGKLSITLVGSSVLASEDKTL 120
I R+E + F L++++I ES IFRDEI+LH L G+L++ LV +L+ D L
Sbjct: 58 IKRSELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQLTLILVDHHILSKSDTAL 117
Query: 121 ESAVVKVIN--PVEQSDA-----NVEFRESSSSLVLKEILQEAPELITEQLAHRLRGSIL 173
E AV +V++ P+E +VE S ++LV + ILQ APE++ Q A L G+I+
Sbjct: 118 EEAVAEVLDHRPIEPKHCPPCHVSVELVGSCATLVTERILQGAPEILDRQTAALLHGTII 177
Query: 174 FKWMTMESE--KISEKQEEILSILEEKFPNLPPREDIINVLQETQFSAQGLSIEQTMLKD 231
+ M+ + K + K + + LE FP+LP R DI + LQ+ +F GL+ EQ + KD
Sbjct: 178 LDCVNMDLKIGKATPKDSKYVEKLEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKD 237
Query: 232 LKELSDGEIKVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFSSYLSEEQQPRR 291
K + +KVAIS + M+LE L SN+ +DL AF +DVL+ + + + +P R
Sbjct: 238 QKTIYRQGVKVAISAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVR 297
Query: 292 QIAVYSENMELCSQICCELEECQNPCLELEPFDCGCDEILVYQQEDPSVTCDQVVLVVKE 351
Q+A++ ++ L + IC LE +P L+L P + Y Q + V+ +++ +++E
Sbjct: 298 QLAIFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKKLLPLLQE 357
Query: 352 VINRRCPEMVSNSRTSSTEAVAG---SAPLSQGSSGIMELYGSDIEPQP 397
++ M S T V+ L + S+ ++ D E P
Sbjct: 358 ALSAYFDSMKIPSGQPETADVSREQVDKELDRASNSLISGLSQDEEDPP 406
>gi|4757766 Rho GTPase activating protein 1 [Homo sapiens]
Length = 439
Score = 111 bits (277), Expect = 1e-23
Identities = 56/147 (38%), Positives = 88/147 (59%), Gaps = 4/147 (2%)
Query: 2919 IIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWM 2978
IIVF+AC +P S + D+ L Y+ TL+ V DY ++YL+ P L W+
Sbjct: 85 IIVFSACRMPPSHQLDH----SKLLGYLKHTLDQYVESDYTLLYLHHGLTSDNKPSLSWL 140
Query: 2979 KKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIP 3038
+ Y+ DR+ +KN+K+ IVHP+ FI+T+L + +P IS KF KI YVN LSELS +
Sbjct: 141 RDAYREFDRKYKKNIKALYIVHPTMFIKTLLILFKPLISFKFGQKIFYVNYLSELSEHVK 200
Query: 3039 MDCIHIPESIIKLDEELREASEAAKTS 3065
++ + IP ++K D+ L+ ++ T+
Sbjct: 201 LEQLGIPRQVLKYDDFLKSTQKSPATA 227
>gi|226423858 PRR5-ARHGAP8 fusion protein [Homo sapiens]
Length = 555
Score = 105 bits (261), Expect = 9e-22
Identities = 51/142 (35%), Positives = 81/142 (57%), Gaps = 4/142 (2%)
Query: 2919 IIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWM 2978
++ F+ C +P S D+ ++E Y+ TL+ V DY IVY + R P LGW+
Sbjct: 157 VVTFSCCRMPPSHELDHQRLLE----YLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWL 212
Query: 2979 KKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIP 3038
+ Y+ DR+ +KNLK+ +VHP+ FI+ + + +P IS KF K+ Y N LSEL +
Sbjct: 213 QSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLK 272
Query: 3039 MDCIHIPESIIKLDEELREASE 3060
D + IP +++ DE+L+ E
Sbjct: 273 YDQLVIPPEVLRYDEKLQSLHE 294
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 105 bits (261), Expect = 9e-22
Identities = 191/915 (20%), Positives = 342/915 (37%), Gaps = 115/915 (12%)
Query: 850 DNSPSEINNEAAPEIWGKKNND-SRDHIFAPGNPSSDLDHTWTNSKPPKEDQNGLVDPKT 908
D++ SE +N ++ N+D S+D+ + ++ D + + S D NG +
Sbjct: 475 DDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNG--NGNN 532
Query: 909 RGKVYEKVDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYS 968
+K DS KG SD DS SD S S+ DS S + S
Sbjct: 533 GNDDNDKSDSG--------KGKSDS----SDS----DSSDSSNSSDSSDSSDSDSSDSNS 576
Query: 969 TSDSYTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSRNRISSGPG 1028
+SDS +S + + D +++ + S D + +++ +D S SS ++ S
Sbjct: 577 SSDSDSSDSDSSDSSDSD-----SSDSSNSSDSSDSSDSSDSSDSS--DSSDSKSDSSKS 629
Query: 1029 NLDMWASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYDDPSMMQLY 1088
D S +SS+ N++ + D ++ +D N S D +SS SS D S
Sbjct: 630 ESDSSDSDSKSDSSDSNSSDSSDNSD----SSDSSNSSNSSDSSDSSDSS-DSSSSSDSS 684
Query: 1089 NETNRQLTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDDCSGGAAIP 1148
N ++ + S+++ + DS D + + + S ++ SD N D D S ++
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSD-SSNSSDS 743
Query: 1149 SDGQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSAPSEHHTLN 1208
SD ++ S+ S + + S S+ +
Sbjct: 744 SDSSDSSNSSDSSD-----------------------------SSDSSNSSDSSDSSDSS 774
Query: 1209 EKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPDAP 1268
+ S ++ DS S SS+ +DS S S++ ++S D+
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS-------SDSSDSDSSNSSDSS 827
Query: 1269 AASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHGDGQSESEK 1328
+S +S+S D D+ + SD+++ + + D S
Sbjct: 828 NSSDSSDSSNSSDSSDSSDSS-DGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN 886
Query: 1329 EAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEICIKSGKISSLAV 1388
E+ ++D D S ++S S+ S S +S + S +S
Sbjct: 887 ESSNSSDSS--DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 1389 TFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEKHLMSQRNSGETTETSD 1448
+ S + + + S + DS D + S+D+ D+ + +S +++++SD
Sbjct: 945 SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS-----DSSDSSDSSD 999
Query: 1449 GMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRVPRSLDFGDVPIDSDVHVSSTCSE 1508
N S + ++ N + N S D + SD SS S+
Sbjct: 1000 SSNS----SDSSDSSDSSDSSNSSDSSN-----------SSDSSNSSDSSDSSDSSDSSD 1044
Query: 1509 ITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSSASSPELNDSSVALSSWGQQPSSGY 1568
+ + D S NS + SS + D SS+ + SS SS E +DSS + +S SS
Sbjct: 1045 SSDSSDSSDSSNSSDSSDSSDSSDSSD-SSDSSDSSDSS-ESSDSSDSSNSSDSSDSSDS 1102
Query: 1569 QEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRINEFEKSFDRKTPTFLEIWNDS 1628
+ + + S + S+ N + S + + N S
Sbjct: 1103 SDSSDSSDSSDSSDSSD--------------------SSNSSDSSDSSDSSDSSDSSNSS 1142
Query: 1629 VDGDSFSSLSSPETGKYSEHSGTHQESNLIASYQEKNEHDISATVQPEDARVISTSSGSD 1688
DS S S ++ S+ S + S+ S N D S + D+ S SS S
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 1689 DDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPKSENIYDYLDSSEPAE 1748
D S + S + ++ + D S + DS S+ + S N D DSS+ ++
Sbjct: 1203 DSSDSSDSS--DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260
Query: 1749 NENKSNPFCDNQQSS 1763
+ + SN D+Q S
Sbjct: 1261 STSDSNDESDSQSKS 1275
Score = 102 bits (255), Expect = 4e-21
Identities = 210/1084 (19%), Positives = 408/1084 (37%), Gaps = 104/1084 (9%)
Query: 556 SGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSPERLKNTGKRIPPTPMNS 615
+G GKDS ++ + + QD +++ + +G S S E GK P ++
Sbjct: 267 AGNGKDS--SNNSKGQEGQDHGKEDDHDSS-----IGQNSDSKEYYDPEGKEDPHNEVDG 319
Query: 616 LVESSPSTEEPASLYTEDMTQKATDTGHMGPPQTHARCSSWWGGLEIDSKNIADAWSS-S 674
++S S E A + ++ +Q+ DT + +SK + + + S
Sbjct: 320 -DKTSKSEENSAGIPEDNGSQRIEDTQKLN---------------HRESKRVENRITKES 363
Query: 675 EQESVFQSPESWKEHK-PSSIDRRASDSVFQPKSLEFTKSGPWESEFGQPE--LGSNDIQ 731
E +V +S + E K PSS +R + V K + + GQ LG +++
Sbjct: 364 ETHAVGKSQDKGIEIKGPSSGNRNITKEV--------GKGNEGKEDKGQHGMILGKGNVK 415
Query: 732 DKNE----ESLPFQNLPMEKSPLPNTSPQGTNHLIE--DFASLWHSGRSPTAMPEPWGNP 785
+ E E ++ P K NT + + DF G P + E GN
Sbjct: 416 TQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGND 475
Query: 786 TDDGEPAAVAPFPAWSAF---------------GKEDHDEALKNTWNLHPTSSKTPSVRD 830
+ E + +++ G ED D + N ++ + D
Sbjct: 476 DANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND 535
Query: 831 PNEWAMAKSGFAFSSSELLDNSPSEINNEAAPEIWGKKNNDSRDHIFAPGNPSSDLDHTW 890
N+ KS S+ D+ S+ +N + ++DS D + N SSD D +
Sbjct: 536 DND----KSDSGKGKSDSSDSDSSDSSNSS-------DSSDSSDSDSSDSNSSSDSDSSD 584
Query: 891 TNSKPPKE-DQNGLVDPKTRGKVYEKVDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDY 949
++S + D + + + DS + + + K SD DS S SD
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK--SDSSKSESDSSDSDSKSDS 642
Query: 950 SASNLGEDSVPSPL-DTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEET 1008
S SN + S S D++ S++ S +S + + + + +S D ++++E +
Sbjct: 643 SDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESS 702
Query: 1009 DIPPQSLQQSSRNRISSGPGNLDMWASPHTDNSSEINTTHNLDENELK-----TEHTDGK 1063
D S SS + SS + D +S +D+S N++ + D ++ ++ +D
Sbjct: 703 DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 762
Query: 1064 NISMEDDVGESSQSS-------YDDPSMMQLYNETNRQLTLLHSSTNSRQTAPDSLDLWN 1116
N S D +SS SS +D S ++++ +SS +S + D N
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSN 822
Query: 1117 RVILEDTQSTATISDMDNDLDWDDCSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEPWG 1176
++ ++ S+ + D D S G+ S +++ + S + +
Sbjct: 823 SSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Query: 1177 LEYQEANQVDWELPASDEHTKDSAPSEHHT-----LNEKSGQLIANSIWDSVMRDKDMSS 1231
+ E++ +S+ DS+ S + + N +NS +S D SS
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS 942
Query: 1232 FMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERE 1291
S S+ S+S++ D++S D+ +S +S+S D D+
Sbjct: 943 DSSDSSDSSNSSDSSNSSDS--SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 1292 TLQSDAASLATRLENPGYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVEN 1351
+ SD++ + ++ + S ++ ++D + +S N
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD----SSDSSN 1056
Query: 1352 ASGISEKGQSDQELSSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLD 1411
+S S+ S S +S+ + S S + S + + + + + S + D
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116
Query: 1412 SRDVQTGM-SADNLQPKDTHEKHLMSQRN-------SGETTETSDGMNFTKYVSVPEKDL 1463
S D S+D+ D+ + S + S +++++SD + + +
Sbjct: 1117 SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176
Query: 1464 EKTEECNFLEPENVGGGPPHRVPRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLP 1523
+ ++ S D D SD SS S+ + + D S S
Sbjct: 1177 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSD 1236
Query: 1524 GAGSSGNFD--RDTISSEYTHSSASSPELNDSSVALSSWGQQPSSGYQEENQGNWSEQNH 1581
+ SS + D + SS+ + SS S+ + ND S + S G ++G ++ S+ NH
Sbjct: 1237 SSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNH 1296
Query: 1582 QESE 1585
S+
Sbjct: 1297 STSD 1300
Score = 80.9 bits (198), Expect = 2e-14
Identities = 211/1156 (18%), Positives = 415/1156 (35%), Gaps = 122/1156 (10%)
Query: 964 DTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSRNRI 1023
+TN +T D T GD E +E+G + N++ + D + ++ S RN
Sbjct: 153 NTNGNT-DKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNED---EIIENSCRNEG 208
Query: 1024 SSGP----------GNLDMWASPHT------DNSSEINTTHNLDENELKTEHTD------ 1061
++ G + +P T DNS + + DE+E + D
Sbjct: 209 NTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAG 268
Query: 1062 -------------GKNISMEDD----VGESSQSS--YDDPSMMQLYNETNRQLTLLHSST 1102
G++ EDD +G++S S YD +NE + T
Sbjct: 269 NGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEEN 328
Query: 1103 -------NSRQTAPDSLDLWNRV-------ILEDTQSTATISDMDNDLDWDDCSGG---- 1144
N Q D+ L +R I +++++ A D ++ S G
Sbjct: 329 SAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNI 388
Query: 1145 ---AAIPSDGQTE----GYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTK 1197
++G+ + G + +T+ V +E G + + N+V SD +
Sbjct: 389 TKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSN-- 446
Query: 1198 DSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSA 1257
S + + ++KS Q + D + D +S SS D+ + + +
Sbjct: 447 -SDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGS 505
Query: 1258 NVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWK 1317
+ K D+ + S T+ S++ + + D ++ S ++ ++ D
Sbjct: 506 DSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 1318 GHGDGQSESEKEAQG-ATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEI 1376
S+S + ++D D + +S N+S S+ S S +S+ +
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 1377 CIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGM-SADNLQPKDTHEKHLM 1435
KS SS + + S ++ + S N DS D S+D+ D+ +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSS-----DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 1436 SQR-NSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRVPRSLDFGDV 1494
S NS +++++SD N ++ S D ++ + + N S D D
Sbjct: 681 SDSSNSSDSSDSSDSSNSSE--SSDSSDSSDSDSSDSSDSSNSNSSDSDS-SNSSDSSDS 737
Query: 1495 PIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDR-DTISSEYTHSSASSPELNDS 1553
SD SS S + + D S NS + SS + D D+ +S ++ S++S + +DS
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 1554 SVALSSWGQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRINEFEKS 1613
S + S SS + + + S + + ++D N + S
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS---------------NSSDSS 842
Query: 1614 FDRKTPTFLEIWNDSVDGDSFSSLSSPETGKYSEHSGTHQESNLIASYQEKNEHDISATV 1673
+DS DG S + ++ S+ S + SN S + ++ S +
Sbjct: 843 DS----------SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 1674 QPEDARVISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPK 1733
D+ S+ SD DS S + +N + + S + D+ N S+ +
Sbjct: 893 DSSDS-----SNSSDSDSSDSSNSSDSS-DSSNSSDSSESSNSSDNSNSSDSSNSSDSSD 946
Query: 1734 SENIYDYLDSSEPAENENKSNPFCDNQQSSPDPWTFSPLTETEMQITAVEKEKRSSPETG 1793
S + + DSS +++ N S+ N S D S +++ + + S+
Sbjct: 947 SSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDS 1006
Query: 1794 TTGDVAWQISPKASFPKNEDNSQLEMLGFSADSTEWWKA-----SPQEGRLIESPFEREL 1848
+ + S + + D+S S+DS++ + S +S +
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066
Query: 1849 SDSSGVLEINSSVHQNASPWGVPVQGDIEPVETHYTNPFSDNHQSPFLEGNGKNSHEQLW 1908
SDSS + + S + S + ++ ++ SD+ S + +S+
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 1909 NIQPRQPDPDADKFSQLVKLDQIKEKDSREQTFVSAAGDELTPETPTQEQCQDTMLPVCD 1968
+ D +D + D + DS + + S + D + D
Sbjct: 1127 SDSSDSSD-SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Query: 1969 HPDTAFTHAEENSCVTSNVSTNEGQETNQWEQEKSYLGEMTNSSIATENFPAVSSPTQLI 2028
D++ + +S +S+ S + + + S + ++SS + E+ + S
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245
Query: 2029 MKPGSEWDGSTPSEDS 2044
S+ S+ S DS
Sbjct: 1246 SSNSSDSSDSSDSSDS 1261
Score = 77.8 bits (190), Expect = 2e-13
Identities = 168/849 (19%), Positives = 306/849 (36%), Gaps = 97/849 (11%)
Query: 497 DPAPMASGQSQQSSHSADYSPADDFFPNSDL-SEGQLPAGPEGLDGMGTNMSNYSSSSLL 555
D + S S SS S+D S +D NS S+ + D ++ SN S SS
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607
Query: 556 SGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSPERLKNTGKRIPPTPMNS 615
S + S + + + DS + S+ + S + +S S + N+ NS
Sbjct: 608 SDSSDSS--DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 616 LVESSPSTEEPASLYTEDMTQKATDTGHMGPPQTHARCSSWWGGLEIDSKNIADAWSSSE 675
+SS S++ S + D + + DS + +D+ +SSE
Sbjct: 666 S-DSSDSSDSSDSSSSSDSSNSS------------------------DSSDSSDSSNSSE 700
Query: 676 QESVFQSPESWKEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEFGQPELGSNDIQDKNE 735
S +S S + +SDS S S +S S+D D ++
Sbjct: 701 SSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 760
Query: 736 ESLPFQNLPMEKSPLPNTSPQGTNHLIEDFASLWHSGRSPTAMPEPWGNPTDDGEPAAVA 795
S N+S + D + +S S + + + D ++ +
Sbjct: 761 SS--------------NSSDSSDSSDSSDSSDSSNSSDSNDS------SNSSDSSDSSNS 800
Query: 796 PFPAWSAFGKEDHDEALKNTWNLHPTSSKTPSVRDPNEWAMAKSGFAFSSSELLDNSPSE 855
+ S+ + D + ++ N +S+ + S N S + SS+ D S S+
Sbjct: 801 SDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN------SSDSSDSSDSSDGSDSD 854
Query: 856 INNEAAPEIWGKKNNDSRDHIFAPGNPSSDLDHTWTNSKPPKEDQNGLVDPKTRGKVYEK 915
+N + ++ S + + SSD + + +S + D +
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914
Query: 916 VDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTS 975
DS N + + SD DS S SD S S+ DS S +N +SDS S
Sbjct: 915 SDSSNSSDSSESSNSSDNSNS-SDSSNSSDSSDSSDSSNSSDSSNSSDSSN--SSDSSDS 971
Query: 976 PTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSRNRISSGPGNLDMWAS 1035
+ + + +S D + ++ +D S S N SS N S
Sbjct: 972 NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN--SSDSSN-----S 1024
Query: 1036 PHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYDDPSMMQLYNETNRQL 1095
+ NSS+ + + + ++ ++ +D + S D +SS SS S + + +
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES 1084
Query: 1096 TLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDDCSGGAAIPSDGQTEG 1155
+ S+NS ++ DS D + D+ ++ SD N D D S ++ SD
Sbjct: 1085 SDSSDSSNSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD-SSDSSDSSDSSNSS 1142
Query: 1156 YMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSAPSEHHTLNEKSGQLI 1215
++ SE D + + DS+ S + + S
Sbjct: 1143 DSSDSSESS---------------------DSSDSSDSSDSSDSSDSSDSSDSSDS---- 1177
Query: 1216 ANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPDAPAASGTSE 1275
+NS S D SS SS +DS + S + + S D+ +S ++E
Sbjct: 1178 SNSSDSSDSSDSSDSS----DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233
Query: 1276 SEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHGDGQ-SESEKEAQGAT 1334
S D D+ + SD++ + + G+G+ S+S+ +++G +
Sbjct: 1234 SSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEG-S 1292
Query: 1335 DRGHLDEEE 1343
D H ++
Sbjct: 1293 DSNHSTSDD 1301
Score = 52.8 bits (125), Expect = 5e-06
Identities = 171/1025 (16%), Positives = 356/1025 (34%), Gaps = 140/1025 (13%)
Query: 1317 KGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEI 1376
+ + +G ++ + D GH ++ V+ +G + ++ E+ +
Sbjct: 151 RSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEII-------ENS 203
Query: 1377 CIKSGKISSLAVTFSPQTEEPEEVLEYEEGS---YNLDSRDVQ-TGMSADNLQPK---DT 1429
C G S + + + +E E G+ LD+ D +G AD + + D
Sbjct: 204 CRNEGNTSEITPQINSKRNGTKEA-EVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDD 262
Query: 1430 HEKHLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRVPRSL 1489
++ + ++S ++ +G + K + ++ + +PE G PH
Sbjct: 263 EDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPE--GKEDPHN----- 315
Query: 1490 DFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSSASSPE 1549
+D D +S E + + + + + + + T S +
Sbjct: 316 -----EVDGDK--TSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAV 368
Query: 1550 LNDSSVALSSWGQQPSSGYQ----EENQGNWSEQNHQESELITTDGQVEIVTKVKDLEK- 1604
+ G PSSG + E +GN +++ + +I G V+ +V ++E
Sbjct: 369 GKSQDKGIEIKG--PSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGP 426
Query: 1605 -------NRINEFEKSFDRKTPTFLEIWNDSVDGDSFSSLSSPETGKYSEHSGTHQESNL 1657
N++ D + + DS D D S S+ S + ++N
Sbjct: 427 GQKSEPGNKVGHSNTGSDSNSDGY-----DSYDFDDKSMQGDDPNS--SDESNGNDDANS 479
Query: 1658 IASYQEKNEHDISATV-QPEDARVISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRA 1716
+ + D S + +D S S G++DD N + D++
Sbjct: 480 ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDK 539
Query: 1717 WDSLNESNKFLVTADPKSENIYDYLDSSEPAENENKSNPFCDNQQSSPDPWTFSPLTETE 1776
DS + + S N D DSS+ +++ S+ D+ S S ++++
Sbjct: 540 SDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDS-----SDSSDSD 594
Query: 1777 MQITAVEKEKRSSPETGTTGDVAWQISPKASFPKNE-DNSQLEMLGFSADSTEWWKASPQ 1835
++ + S ++ + D + K+ K+E D+S + S+DS +
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654
Query: 1836 EGR-LIESPFERELSDSSGVLEINSSVHQNASPWGVPVQGDIEPVETHYTNPFSDNHQSP 1894
+ S + SDSS + +SS + S E+ ++ SD+ S
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714
Query: 1895 FLEGNGKNSHEQLWNIQPRQPDPDADKFSQLVKLDQIKEKDSREQTFVSAAGDELTPETP 1954
+ + NS D+D + D DS + + S + D
Sbjct: 715 SSDSSNSNSS-------------DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 761
Query: 1955 TQEQCQDTMLPVCDHPDTAFTHAEENSCVTSNVSTNEGQETNQWEQEKSYLGEMTNSSIA 2014
+ D++ + +S +SN S + + + S + +NSS +
Sbjct: 762 SNSS------------DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 2015 TENFPAVSSPTQLIMKPGSEWDGSTPSEDSRGTFVPDILHGNFQEGGQLASAAPDLWIDA 2074
+++ S+ D S S+ S + D +S + D
Sbjct: 810 SDS------------SDSSDSDSSNSSDSSNSSDSSD------------SSNSSD----- 840
Query: 2075 KKPFSLKADGENPDILTHCEHDSNSQASDSPDICHDSEAKQETEKHLSACMGPEVESSEL 2134
S +DG + D + ++S +SDS D + S++ ++ + S+ +SS
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900
Query: 2135 CLTEPEIDEEPIYEPGREFVPSNAELDSENATVLPPIGYQADIKGSSQPASHKGSPEPSE 2194
++ DS N++ +D SS + + S + S
Sbjct: 901 SDSDSS--------------------DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 2195 I--NGDNSTGLQVSEKGASPDMAPILEPVDRRIPRIENVATSIFVTHQEPTPEGDGSWIS 2252
+ D+S S+ S D + + D + + S + + D S S
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS-----SDSSDSSDSSDSS 995
Query: 2253 DSFSPESQPGARALFDGDPHLSTENPALVPDALLASDTCLDISEAAFDHSFSDASGLNTS 2312
DS + + D ++ + + D+ +SD+ D S+++ SD+S + S
Sbjct: 996 DSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS-DSSDSSDSSDSSDSSDSSDS 1054
Query: 2313 TGTID 2317
+ + D
Sbjct: 1055 SNSSD 1059
Score = 33.1 bits (74), Expect = 4.4
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 2/79 (2%)
Query: 2789 NSLDLNDTHPRRIKLTAPNINLSLDQSEGSILSD--DNLDSPDEIDINVDELDTPDEADS 2846
+S D +D+ + + N S D S+ S SD ++ DS D D + D+ DE+DS
Sbjct: 1212 DSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDS 1271
Query: 2847 FEYTGHDPTANKDSGQESE 2865
+G+ DS +SE
Sbjct: 1272 QSKSGNGNNNGSDSDSDSE 1290
>gi|66346660 Rho GTPase activating protein 8 isoform 2 [Homo sapiens]
Length = 433
Score = 105 bits (261), Expect = 9e-22
Identities = 51/142 (35%), Positives = 81/142 (57%), Gaps = 4/142 (2%)
Query: 2919 IIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWM 2978
++ F+ C +P S D+ ++E Y+ TL+ V DY IVY + R P LGW+
Sbjct: 35 VVTFSCCRMPPSHELDHQRLLE----YLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWL 90
Query: 2979 KKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIP 3038
+ Y+ DR+ +KNLK+ +VHP+ FI+ + + +P IS KF K+ Y N LSEL +
Sbjct: 91 QSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLK 150
Query: 3039 MDCIHIPESIIKLDEELREASE 3060
D + IP +++ DE+L+ E
Sbjct: 151 YDQLVIPPEVLRYDEKLQSLHE 172
>gi|66346662 Rho GTPase activating protein 8 isoform 1 [Homo sapiens]
Length = 464
Score = 90.1 bits (222), Expect = 3e-17
Identities = 52/173 (30%), Positives = 81/173 (46%), Gaps = 35/173 (20%)
Query: 2919 IIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWM 2978
++ F+ C +P S D+ ++E Y+ TL+ V DY IVY + R P LGW+
Sbjct: 35 VVTFSCCRMPPSHELDHQRLLE----YLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWL 90
Query: 2979 KKCYQMIDR-------------------------------RLRKNLKSFIIVHPSWFIRT 3007
+ Y+ DR R +KNLK+ +VHP+ FI+
Sbjct: 91 QSAYKEFDRKDGDLTMWPRLVSNSKLKRSSHLSLPKYWDYRYKKNLKALYVVHPTSFIKV 150
Query: 3008 ILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREASE 3060
+ + +P IS KF K+ Y N LSEL + D + IP +++ DE+L+ E
Sbjct: 151 LWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHE 203
>gi|207450721 ganglioside induced differentiation associated protein 2
isoform b [Homo sapiens]
Length = 496
Score = 60.5 bits (145), Expect = 3e-08
Identities = 32/130 (24%), Positives = 62/130 (47%)
Query: 2939 MENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFII 2998
M+ LY I ++ + ++Y++VY + T ++KK Y ++D + ++NLK+
Sbjct: 367 MDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYF 426
Query: 2999 VHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREA 3058
VHP++ + F S KI +V+SL +L I + I P +++ D +R
Sbjct: 427 VHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARVRST 486
Query: 3059 SEAAKTSCLY 3068
+ +Y
Sbjct: 487 RSSPSPGMVY 496
>gi|8923143 ganglioside induced differentiation associated protein 2
isoform a [Homo sapiens]
Length = 497
Score = 56.6 bits (135), Expect = 4e-07
Identities = 30/114 (26%), Positives = 57/114 (50%)
Query: 2939 MENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFII 2998
M+ LY I ++ + ++Y++VY + T ++KK Y ++D + ++NLK+
Sbjct: 367 MDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYF 426
Query: 2999 VHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLD 3052
VHP++ + F S KI +V+SL +L I + I P +++ D
Sbjct: 427 VHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYD 480
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 51.6 bits (122), Expect = 1e-05
Identities = 188/939 (20%), Positives = 338/939 (35%), Gaps = 161/939 (17%)
Query: 1321 DGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSD-QELSSLVASEHQEICIK 1379
+ S S+ +A + D +DE + SG E+ SG+ S+ +++SS SE + +K
Sbjct: 2619 ESSSSSDPDADCSVD---VDEPKHTGSG-EDESGVPVLVTSESRKVSSSSESEPELAQLK 2674
Query: 1380 SGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQP-----------KD 1428
G S L PE V+ + S S D + QP +D
Sbjct: 2675 KGADSGLL---------PEPVIRVQPPSPLPSSMDSNSSPEEVQFQPVVSKQYTFKMNED 2725
Query: 1429 THEK------------HLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPEN 1476
T E+ HL R++ +TE D ++ K +D ++ + C+
Sbjct: 2726 TQEEPGKSEEEKDSESHLAEDRHA-VSTEAED-RSYDKL----NRDTDQPKICD------ 2773
Query: 1477 VGGGPPHRVPRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTI 1536
G G P S P+ S + S T ++ + + +L G ++DT
Sbjct: 2774 -GHGCEAMSPSS---SAAPVSSGLQ-SPTGDDVDEQPVIYKESLAL-----QGTHEKDTE 2823
Query: 1537 SSEYTHSSASSPELNDSSVALSSWGQQPS---SGYQEENQGNWSEQNHQESELITTDGQV 1593
E S A SP+ + S + SS P S +E ++ + + Q++E+ TD
Sbjct: 2824 GEELDVSRAESPQADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEVTKTDETF 2883
Query: 1594 EIVTKVKDLEKNRINEFEKSFDRKTPTFLEIWNDSVDGDSFSSL--SSPETGKYS-EHSG 1650
E + K + + I F P ND + +S + P +S E S
Sbjct: 2884 ENLPKDCPSQDSSITTQTDRFSMDVPVSDLAENDEIYDPQITSPYENVPSQSFFSSEESK 2943
Query: 1651 THQESNLIASYQEKNEHDISATVQPEDARVISTSSG---SDDDSVGGEESIEEEIQVANC 1707
T ++N S+ + ++ T ED V S+SSG S + + G++ E
Sbjct: 2944 TQTDANHTTSFHSSEVYSVTITSPVEDVVVASSSSGTVLSKESNFEGQDIKME------- 2996
Query: 1708 HVAEDESRAWDSLNESNKFLVTADPKSENIYDYLDSSEPAENENKSNPFCDNQQSSPDPW 1767
++ ES W+ + +D S + + ++ E S D W
Sbjct: 2997 --SQQESTLWE---------MQSDSVSSSFEPTMSATTTVVGEQISKVIITKTDVDSDSW 3045
Query: 1768 TFSPLTETEMQITAVEKEKR------SSPETGTTGDVAWQISP-KASFPKNEDNSQLEML 1820
+ + + E+E++ GTT D +P + P +E N L
Sbjct: 3046 SEIREDDEAFEARVKEEEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQE 3105
Query: 1821 GFSADSTEWWKASPQEGRLIESPFE-RELSDSSGVLEINSSVHQNASPWGVPVQGDIEPV 1879
G + T + + F ++ S ++ V + A+ D P+
Sbjct: 3106 GKLFEMTRSGAIDMTKRSYADESFHFFQIGQESREETLSEDVKEGAT------GADPLPL 3159
Query: 1880 ETHYTNPFSDNHQSPFLEGNGKNSHEQLWNIQPRQP-DPDADKFSQLVKLDQIKEKDSRE 1938
ET S E L + ++ D +AD V ++++E + +
Sbjct: 3160 ET---------------------SAESLALSESKETVDDEADLLPDDVS-EEVEEIPASD 3197
Query: 1939 QTFVSAAGDELTPETPTQE------------QCQD-------TMLPVCDHPDTAFTHAEE 1979
S G + ETPT+E Q D + D + A +
Sbjct: 3198 AQLNSQMGISASTETPTKEAVSVGTKDLPTVQTGDIPPLSGVKQISCPDSSEPAVQVQLD 3257
Query: 1980 NSCVTSNVSTNEGQET--NQWEQEKSYLGEMTNSSIATENFPAVSSPTQLIMKPGSEWDG 2037
S +T +V ++ G ++ + E++KS + T EN P S +++ ++
Sbjct: 3258 FSTLTRSVYSDRGDDSPDSSPEEQKSVIEIPT---APMENVPFTESKSKIPVRTMPTSTP 3314
Query: 2038 STPSEDSRGTFVPDILHGNFQEGGQLASAAPDLWIDAKKPFSLKADGENPDILTHCEHDS 2097
+ PS + + D L + E + A P + K P + + + D+ T +
Sbjct: 3315 APPSAEYESSVSEDFL-SSVDEENKADEAKPKSKLPVKVPLQ-RVEQQLSDLDTSVQKTV 3372
Query: 2098 NSQASDSPDICHDSEAKQETE-KHLSACMGPEVESSELCLTEPEIDEEPIYEPGREFVPS 2156
Q D I D+ +K E++ L + V++ TE E E
Sbjct: 3373 APQGQDMASIAPDNRSKSESDASSLDSKTKCPVKTRSYTETETESRER----------AE 3422
Query: 2157 NAELDSENATVLPPI-GYQADIKGSSQPASHKGSPEPSE 2194
EL+SE P I + +K S +S +G P++
Sbjct: 3423 ELELESEEGATRPKILTSRLPVKSRSTTSSCRGGTSPTK 3461
Score = 37.0 bits (84), Expect = 0.30
Identities = 53/244 (21%), Positives = 91/244 (37%), Gaps = 38/244 (15%)
Query: 524 NSDLSEGQLPAGPEGLDGMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSER 583
+ D+ EG A P L+ +++ S + D L + E V+ + P +++
Sbjct: 3144 SEDVKEGATGADPLPLETSAESLALSESKETVDDEA-DLLPDDVSEEVE--EIPASDAQL 3200
Query: 584 NLSLTDFVGDESPSPERLKNTGKRIPPT------PMNSLVE-SSPSTEEPASLYTEDMTQ 636
N + E+P+ E + K +P P++ + + S P + EPA D +
Sbjct: 3201 NSQMGISASTETPTKEAVSVGTKDLPTVQTGDIPPLSGVKQISCPDSSEPAVQVQLDFST 3260
Query: 637 KA----TDTGHMGPPQTHARCSSWWGGLEIDSKNIADAWSSSEQESVFQSPESWKEHKPS 692
+D G P S EQ+SV + P + E+ P
Sbjct: 3261 LTRSVYSDRGDDSPDS-----------------------SPEEQKSVIEIPTAPMENVPF 3297
Query: 693 SIDRRASDSVFQPKSLEFTKSGPWESEFGQPELGSNDIQDKNEESLPFQNLPMEKSPLPN 752
+ + P S S +ES + L S D ++K +E+ P LP+ K PL
Sbjct: 3298 TESKSKIPVRTMPTSTPAPPSAEYESSVSEDFLSSVDEENKADEAKPKSKLPV-KVPLQR 3356
Query: 753 TSPQ 756
Q
Sbjct: 3357 VEQQ 3360
Score = 33.1 bits (74), Expect = 4.4
Identities = 53/211 (25%), Positives = 78/211 (36%), Gaps = 25/211 (11%)
Query: 1999 EQEKSYLGEMTNSSIATENFPAVSSPTQLIMKPGSEWDGSTPSEDSRGTFVPDILHGNFQ 2058
E++ E T + TE PT + GSE G+T +EDS + +FQ
Sbjct: 2255 EEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEERGATVTEDS------ETSTESFQ 2308
Query: 2059 EGGQLAS---AAPDLWIDAKKPFSLKADGENPDILTH---CEHDSNSQASDSPDICHDSE 2112
+ L S +P D S+ E P LT C+ + S + DSE
Sbjct: 2309 KEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDEGQRTFGSSAHKTQTDSE 2368
Query: 2113 AKQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGREFVPSNAE--LDSENATVLPP 2170
++ T P E+S T E + + P E L S ++ VL
Sbjct: 2369 VQESTATSDETKALPLPEASVKTDTGTESKPQGVIRS-----PQGLELALPSRDSEVL-- 2421
Query: 2171 IGYQADIKGSSQPASHKGSPEPSEINGDNST 2201
+ + S SHK S E S + DNS+
Sbjct: 2422 ----SAVADDSLAVSHKDSLEASPVLEDNSS 2448
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 51.2 bits (121), Expect = 2e-05
Identities = 306/1540 (19%), Positives = 514/1540 (33%), Gaps = 284/1540 (18%)
Query: 432 TIRSSRSSKESSVFLSDDSPVG--EGAGPHHTLLPGLDSYSPIP-----EGAVAEEHAWS 484
T SS SS ++ F + + +G E + P H+ P + +P P G V E A+
Sbjct: 447 TYHSSPSSTPTTHFSASSTTLGHSEESTPVHSS-PVATATTPPPARSATSGHVEESTAYH 505
Query: 485 GEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDFFPNSDLSEGQLPAGPEGLDGMG- 543
G +F + SG S++S A + + +S S A +G
Sbjct: 506 RSPGST-QTMHFPESSTTSGHSEES---ATFHGSTTHTKSSTPSTTAALAHTSYHSSLGS 561
Query: 544 TNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSP----- 598
T +++ SS +SG ++S H S ++ VGD +PSP
Sbjct: 562 TETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSV----LVGDSTPSPISSGS 617
Query: 599 -ERLKNTGKRIPP------TPMNSLVESSPSTEEPASLYTEDMTQKATDTGHMGPPQTHA 651
E G P T S S +T PAS+ + +++++T T H P TH
Sbjct: 618 METTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEEST-TSHSRPGSTHT 676
Query: 652 RC---SSWWGGLEIDSKNIADAWSSSEQESVFQSPESWKEHKPSSIDRRASDSVFQPKSL 708
S+ GL S ES H +D+ P S
Sbjct: 677 TAFPGSTTMPGL---------------------SQESTASHSSPG----PTDTTLSPGST 711
Query: 709 EFTKSGPWESEFGQPELGSNDIQDKNEESLPFQNLP--MEKSPLP-NTSPQGTNHLIEDF 765
+ GP E F + P E + LP NT+ G L+E
Sbjct: 712 TASSLGP--------------------EYTTFHSRPGSTETTLLPDNTTASG---LLEAS 748
Query: 766 ASLWHSGRSPTAMPEPWGNPTDDGEPAAVAPFPAWSAFGKEDHDEALKNTWNLHPTSSKT 825
+ S RSP P G+ T GE +P+ +D A T + S T
Sbjct: 749 MPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPS-----SKDTRPAPPTTTSAFVEPS-T 802
Query: 826 PSVRDPNEWAMAKSGFAFSSSELLDNSPSEINNEAAPEIWGKKNNDSRDHIFAPGNPS-S 884
S P+ ++S L++ S + ++ + + +D+ S S
Sbjct: 803 TSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 862
Query: 885 DLDHTWTNSKPPKEDQNGLVDPKTRGKVYEKVDSWNLFEENMKKGGSDVLVPWED-SFLS 943
HT +++ P T + E+ S++ GS + D S S
Sbjct: 863 STTHTISSA------------PSTTSALVEEPTSYH------SSPGSTATTHFPDSSTTS 904
Query: 944 YKCSDYSASNLGEDS-----VPSPLDTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFES 998
+ + +AS+ +D+ +P+ T+ +S TSP +G + T G
Sbjct: 905 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 964
Query: 999 KD----GNSTAEETDIPPQSLQQS--------SRNR------------------------ 1022
+ + + T + P S S SR+R
Sbjct: 965 RSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTT 1024
Query: 1023 ISSGPGNLD---MWASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSY 1079
S PG+ D + AS T S+ +TT + T + G ++ G+ S + +
Sbjct: 1025 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTAL--SFGQESTTFH 1082
Query: 1080 DDPSMMQ--LYNETN------RQLTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISD 1131
+P L+ ++ T +HSST S +T + + +STA +
Sbjct: 1083 SNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL--QGESTAFQTH 1140
Query: 1132 MDNDLDWDDCSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPA 1191
+ A P + T + + GS P T F PA
Sbjct: 1141 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF----------------------PA 1178
Query: 1192 SDEHTKDSAPSE-HHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPP 1250
S + S S H+ + SG +++ + R + +S + PGS+ IT LP
Sbjct: 1179 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT-----TLPG 1233
Query: 1251 EIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYF 1310
+ + T +P + T+ S A ++ L + E T +S S + +
Sbjct: 1234 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGE-ESTTSRSQPGSTHSTVS----- 1287
Query: 1311 PHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVA 1370
P G + + ++G+T+ + +++ S G+ S A
Sbjct: 1288 PASTTTPGLSEESTTVYSSSRGSTE----------TTVFPHSTTTSVHGEEPTTFHSRPA 1337
Query: 1371 SEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTH 1430
S H + + S L TE E ++ QTG+ A L D
Sbjct: 1338 STHTTLFTEDSTTSGL-------TE--------ESTAFPGSPASTQTGLPA-TLTTADLG 1381
Query: 1431 EKHLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGP--PHRVPRS 1488
E+ +SG T T V E + + E + G P P +S
Sbjct: 1382 EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSS-TETTTLPGSPTTPSLSEKS 1440
Query: 1489 LDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSSASSP 1548
F P D +S + + + + +S PG+ + F T +S+ + +S
Sbjct: 1441 TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSH 1500
Query: 1549 ELNDSSVALSSWGQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRIN 1608
S+ A S G +S +++ S E+ L+ D T L
Sbjct: 1501 SSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDD------TITSGL------ 1548
Query: 1609 EFEKSFDRKTPTFLEIWNDSVDGDSFSSLSSPETGKYSEHSGTHQESNLIASYQEKNEH- 1667
+ TPT S SL + T S +G +ES S+ ++
Sbjct: 1549 -----VEASTPTH----------SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTT 1593
Query: 1668 -----------DISATVQPEDARVISTSSGSDDDSVG-GEESIEEEIQVANCHVAEDESR 1715
++S T + +T + ++G EES A +R
Sbjct: 1594 PSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTR 1653
Query: 1716 AWDSLNESNKFLVTADPKSENIYDYLDSSEPAENENKSNPFCDNQQSSPDPWTFSPLTET 1775
+ S+ S S+ A KS F + + SPD T SP + T
Sbjct: 1654 SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR-SPDT-TLSPASTT 1711
Query: 1776 EMQITAVEKEKRSSPETGTTGDVAWQISPKASFPKNEDNSQLEMLG-----FSADSTEWW 1830
++ E+ S G+T A+ S E + G S ST
Sbjct: 1712 SSGVS--EESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 1769
Query: 1831 KASPQEGRLIESPFEREL------SDSSGVLEINSSVHQN 1864
P+ SP E + +SG+LE ++ VH +
Sbjct: 1770 SLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSS 1809
Score = 49.3 bits (116), Expect = 6e-05
Identities = 207/1016 (20%), Positives = 330/1016 (32%), Gaps = 125/1016 (12%)
Query: 366 TSSTEAVAGSAPLSQGSSGIMELYGSDIEP--QPSSVNFIENPPDLNDSNQAQVDANVDL 423
T+S + ++ +S GS+ I L GS P +S F +P +
Sbjct: 3849 TTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTT----------- 3897
Query: 424 VSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDS-----YSPIP---EG 475
+SP A++ S +ES+ S P T PGL YS P E
Sbjct: 3898 LSP----ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTET 3953
Query: 476 AVAEEHAWSGEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDFFPNSDLS-EGQLPA 534
V + E F+ PA + + S ++ + FP S S + LPA
Sbjct: 3954 TVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA 4013
Query: 535 G-------------PEGLDGMGTNMS--NYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRD 579
P GT +S ++S L+ + L E SP
Sbjct: 4014 TLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT 4073
Query: 580 NSERNLSLTDFVGDESPSPERLKNTGKRIPPTPMNSLV--ESSPSTEEPASLYTEDMTQK 637
S S T + SP P T +S V ESS S +P S +T
Sbjct: 4074 PSLSEKSTTFYTSPRSPD-------ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDS 4126
Query: 638 ATDTGHMGPPQT-HARCSSWWGGLEIDSKNIADAWSSSEQESVFQSPESWKEHKPSSIDR 696
T +G P T H+ S L S A S +Q + F S E D
Sbjct: 4127 TTTSGLSQEPTTSHSSQGSTEATL---SPGSTTASSLGQQSTTFHSSPGDTETTLLPDDT 4183
Query: 697 RASDSVFQPKSLEFTKSGPWESEFGQPELGSNDIQDKNEESLPFQNLPMEKSPLPNTSPQ 756
S V + + + +G + S +Q EES FQ+ P P SP
Sbjct: 4184 ITSGLV-EASTPTHSSTGSLHTTLTPASSTSTGLQ---EESTTFQSWPSSSDTTP--SPP 4237
Query: 757 GTNHLIEDFASLWHSGRSPTAMPEPWGNPTDDG---EPAAVAPFP---AWSAFGKEDHDE 810
T + + ++ +HS S T + T G E V P + F
Sbjct: 4238 STTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATS 4297
Query: 811 ALKNTWNLHPTSS-KTPSVRDPNEWAMAKSGFAFSSSELLDNSPSEINNEAAPEIWGKKN 869
L P SS T + P A ++ SP + A+ G
Sbjct: 4298 VLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSE 4357
Query: 870 NDSRDHIFAPGN------------PSSDLDHTWTNSKPPKEDQNGLVDPKTRGKVYEKVD 917
+ H PG+ P + T ++S P D T + +
Sbjct: 4358 ESTTSH-SRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPEST 4416
Query: 918 SWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPT 977
++ + G ++ + +++ S + + S + L ST+ S T
Sbjct: 4417 TF-----HSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTT 4471
Query: 978 FAG--DEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSS--------RNRISSGP 1027
F + K+T P F S + P SS + S P
Sbjct: 4472 FQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 4531
Query: 1028 GNLDMWASPHTDNSS---EINTTHNLDENELKTEHTDGKNISM---EDDVGESSQSSYDD 1081
SP +S E +TT++ +T H N + E+ S +++
Sbjct: 4532 VATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTI 4591
Query: 1082 PSMMQLYNETNRQLTLLHSSTNSRQTA--PDSLDLWNRVILEDTQSTATISDMDNDLDWD 1139
S + + T HSS S T PDS R +STA+ S
Sbjct: 4592 SSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR----SEESTASHSS-------Q 4640
Query: 1140 DCSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDS 1199
D +G +P+ T + E + + + +E L E + + S
Sbjct: 4641 DATGTIVLPARSTTSVLLGEST--TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSS 4698
Query: 1200 APSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANV 1259
P+ H + S + S + + +++ P + T S E S +
Sbjct: 4699 TPTTHFS---ASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 4755
Query: 1260 KDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDP 1315
+ H P++ ASG SE E+ SH + T+ S ++ + +E P + H P
Sbjct: 4756 QTMHFPESSTASGRSE-ESRTSH----SSTTHTISSPPSTTSALVEEPTSY-HSSP 4805
Score = 44.3 bits (103), Expect = 0.002
Identities = 253/1310 (19%), Positives = 425/1310 (32%), Gaps = 194/1310 (14%)
Query: 362 SNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPDLNDSNQAQVDANV 421
S SR ST A P S + G+ + + P S + P S +Q
Sbjct: 997 SRSRPGSTHTTA--FPDSTTTPGLSR-HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTS 1053
Query: 422 DLVSPDSGLATIRSSRSS----KESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAV 477
S + A S ++ +ES+ F S+ H TL P + S I E A
Sbjct: 1054 HSSSGSTDTALSPGSTTALSFGQESTTFHSNPGST------HTTLFPDSTTSSGIVE-AS 1106
Query: 478 AEEHAWSGEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDFFPNSDLSEGQLPAGPE 537
H+ +G PA S Q S + PA S S P
Sbjct: 1107 TRVHSSTGSPRT-----TLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES 1161
Query: 538 GL---DGMGTNMSNYSSSSLLSGAGKDSLVEH---DEEFVQRQDSPRDNSERNLSLTDFV 591
T +++ +SS SG + S + H D + S R S T +
Sbjct: 1162 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI 1221
Query: 592 GDESPS----PERLKNTGKRIPPTPMNSLVESSPSTEEPASLYTEDMTQKATDTGHMGPP 647
S P G T S S +T PAS+ + + +++T T P
Sbjct: 1222 SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST-TSRSQPG 1280
Query: 648 QTHAR---CSSWWGGLEIDSKNIADAWSSSEQESVFQSPESWKEH--KPSSIDRRASDSV 702
TH+ S+ GL +S + + S + +VF + H +P++ R + +
Sbjct: 1281 STHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTH 1340
Query: 703 FQPKSLEFTKSG-----------PWESEFGQPELGSNDIQDKNEESLPFQNLPMEKSPLP 751
+ + T SG P ++ G P + D EES F +
Sbjct: 1341 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLP--ATLTTADLGEESTTFPSSSGSTGTKL 1398
Query: 752 NTSPQGTNHLIEDF--ASLWHSGRSPTAMPEPWGNPTDDGEPAAVAPFPAWSAFGKEDHD 809
+ + T+ L+ + + L S T +P G+PT P+ S +
Sbjct: 1399 SPARSTTSGLVGESTPSRLSPSSTETTTLP---GSPTT----------PSLSEKSTTFYT 1445
Query: 810 EALKNTWNLHPTSSKTPSVRDPNEWAMAKSGFAFSSSELLDNSPSEINNEAAPEIWGKKN 869
L P ++ + V + + + ++ G +++ + S+++ E +
Sbjct: 1446 SPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTS---HSS 1502
Query: 870 NDSRDHIFAPGNPS------------SDLDHTWTNSKPPKEDQNGLVDPKT-----RGKV 912
S + +PG+ + S T T P +GLV+ T G +
Sbjct: 1503 QGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL 1562
Query: 913 YEKVDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDS 972
+ + + +++ S W S SD + S G + P + T Y + S
Sbjct: 1563 HTTLTPASSTSAGLQEE-STTFQSWPSS------SDTTPSPPGTTAAPVEVSTTYHSRPS 1615
Query: 973 YTSPTF---------AGDEKETEHK-PFAKE---------------EGFESKDGNSTAEE 1007
T T +E T H P A E S + + E
Sbjct: 1616 STPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTET 1675
Query: 1008 TDIPPQS----LQQSSRNRISSGPGNLDMWASPHTDNSSEINTTHNLDENELKTEHTDG- 1062
T +P + L + S SS P + D SP + SS ++ + + HT
Sbjct: 1676 TALPGSTTTAGLSEKSTTFYSS-PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAF 1734
Query: 1063 ------KNISMEDDVGESSQSSYDDPSM--MQLYNETNRQLTLLHSSTNSRQTAPDSLDL 1114
+S E SS S D + + T HSS S +T
Sbjct: 1735 PGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETT------ 1788
Query: 1115 WNRVILEDTQSTATISDMDNDLDWDDCSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEP 1174
+L D + + + + + S + G T + T Q P
Sbjct: 1789 ----LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTR--------QGESTTFQSWP 1836
Query: 1175 WGLEYQEANQVDW----ELPASDEHTKDSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMS 1230
+ A EL + + S P+ H + S + S + + ++
Sbjct: 1837 SSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA---SSTTLGRSEESTTVHSSPVA 1893
Query: 1231 SFMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTER 1290
+ P + T S E S + + H P++ ASG SE E+ SH +
Sbjct: 1894 TATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE-ESRTSH----SSTT 1948
Query: 1291 ETLQSDAASLATRLENPGYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVE 1350
T+ S ++ + +E P + H P G + + +T G +E S +
Sbjct: 1949 HTISSPPSTTSALVEEPTSY-HSSP------GSTATTHFPDSSTTSGRSEESTASHSSQD 2001
Query: 1351 NASGISEKGQSDQELSSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNL 1410
I +S +S++ E I SG + + A+ S T L + +++
Sbjct: 2002 ATGTIVLPARS---TTSVLLGESTTSPISSGSMETTALPGSTTTPG----LSEKSTTFHS 2054
Query: 1411 DSRDVQTGMSADNLQPKDTHEKHLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKT---- 1466
R T +S + E+ S G T T+ F + P T
Sbjct: 2055 SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA----FPDSTTTPGLSRHSTTSHS 2110
Query: 1467 ----EECNFLEPENVGGGPPHRVPRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSL 1522
+ L GP S P +D +S + + +S
Sbjct: 2111 SPGSTDTTLLPASTTTSGPSQ---ESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS 2167
Query: 1523 PGAGSSGNFDRDTIS------SEYTHSSASSPELNDSSVALSSWGQQPSS 1566
PG+ + F T S S HSS SP S + +S G Q S
Sbjct: 2168 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 2217
Score = 39.7 bits (91), Expect = 0.047
Identities = 386/2066 (18%), Positives = 663/2066 (32%), Gaps = 345/2066 (16%)
Query: 376 APLSQGSSGIM-ELYGSDIEPQPSSVNFIENPPDLNDSNQAQVDANVDLVSPDSGL--AT 432
+P +SG++ E S + P + + P ++ SPD+ L AT
Sbjct: 2482 SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPAT 2541
Query: 433 IRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGA--------VAEEHAWS 484
SS S+ESS S A P T PGL +S + + S
Sbjct: 2542 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 2601
Query: 485 GEHGE----HFDLFNFDPA-------PMASGQSQQSSHSADYSPADDFFPNSDLSEGQLP 533
G E H + D A ++ GQ + HS+ S FP+S S G +
Sbjct: 2602 GPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 2661
Query: 534 AGPE--------------------GLDGMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQR 573
A GL G T + +S+ + + + EE
Sbjct: 2662 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTY 2721
Query: 574 QDSPRD----------------------NSERNLSLTDFVGDESPSPERLKNTGKRIPP- 610
SP +S + S T S + R ++T RI P
Sbjct: 2722 HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 2781
Query: 611 --------------------TPMNSLVESSPSTEEPASLYTEDMTQKATDTGHMGPPQTH 650
T S S +T PAS+ + + +++T T P TH
Sbjct: 2782 STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST-TSRSQPGSTH 2840
Query: 651 AR---CSSWWGGLEIDSKNIADAWSSSEQESVF--QSPESWKEHKPSSIDRRASDSVFQP 705
+ S+ GL +S + + S + +VF + S + +P++ R + +
Sbjct: 2841 STVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTL 2900
Query: 706 KSLEFTKSG-----------PWESEFGQPELGSNDIQDKNEESLPFQNLPMEKSPLPNTS 754
+ + T SG P ++ G P + D EES F + + +
Sbjct: 2901 FTEDSTTSGLTEESTAFPGSPASTQTGLP--ATLTTADLGEESTTFPSSSGSTGTTLSPA 2958
Query: 755 PQGTNHLIEDF--ASLWHSGRSPTAMPEPWGNPTDDGEPAAVAPFPAWSAFGKEDHDEAL 812
T+ L+ + + L S T +P G+PT P+ S +
Sbjct: 2959 RSTTSGLVGESTPSRLSPSSTETTTLP---GSPTT----------PSLSEKSTTFYTSPR 3005
Query: 813 KNTWNLHPTSSKTPSVRDPNEWAMAKSGFAFSSSELLDNSPSEINNEAAPEIWGKKNNDS 872
L P ++ + V + + + ++ G +++ + S ++ E + S
Sbjct: 3006 SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA---SHSSQGS 3062
Query: 873 RDHIFAPGNPS------------SDLDHTWTNSKPPKEDQNGLVDPKT-----RGKVYEK 915
+ +PG+ + S T T P +GLV+ T G ++
Sbjct: 3063 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 3122
Query: 916 VDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTS 975
+ + +++ S W S SD + S G + P + T Y + S T
Sbjct: 3123 LTPASSTSAGLQE-ESTTFQSWPSS------SDTTPSPPGTTAAPVEVSTTYHSRPSSTP 3175
Query: 976 PTF---------AGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSRNRISSG 1026
T +E T H ++T+ P S S ++
Sbjct: 3176 TTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTAL 3235
Query: 1027 PG----------NLDMWASPHTDNS--SEINTTHNLDENELKTEHTDGKNISMEDDVGES 1074
PG + ++SP + ++ S +TT + E T H+ + G +
Sbjct: 3236 PGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGST 3295
Query: 1075 SQSSYDDPSMMQLYNETNRQLTLLHSSTNSRQTAPDSLDLWN------RVILEDTQSTAT 1128
+ S + + TL ST + P+S + +L D + +
Sbjct: 3296 TMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASG 3355
Query: 1129 ISDMDNDLDWDDCSGGAAIPSDGQT--EGYMAE-GSEPETRFTVRQLEPWGLEYQEANQV 1185
+ + + S + G T +G S P ++ T + E +
Sbjct: 3356 LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTT 3415
Query: 1186 DWELPASDEHTKDSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQ 1245
P+S T SA S +E+S + + +++ P + T S
Sbjct: 3416 SHGSPSSTPTTHFSASSTTLGRSEES----------TTVHSSPVATATTPSPARSTTSGL 3465
Query: 1246 RELPPEIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLE 1305
E S + + H P++ SG E E+ SH + T+ S ++ + +E
Sbjct: 3466 VEESTTYHSSPGSTQTMHFPESDTTSGRGE-ESTTSH----SSTTHTISSAPSTTSALVE 3520
Query: 1306 NPGYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQEL 1365
P + H P G + + +T G +E S + I +S
Sbjct: 3521 EPTSY-HSSP------GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARS---T 3570
Query: 1366 SSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQ 1425
+S++ E I SG + + A+ S T L + +++ R T +S +
Sbjct: 3571 TSVLLGESTTSPISSGSMETTALPGSTTTPG----LSEKSTTFHSSPRSPATTLSPASTT 3626
Query: 1426 PKDTHEKHLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRV 1485
E+ S G T T+ F + P T H
Sbjct: 3627 SSGVSEESTTSHSRPGSTHTTA----FPDSTTTPGLSRHSTTS--------------HSS 3668
Query: 1486 PRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSL--PGAGSSGNFDRD--------- 1534
P S D +P + S + E T + GS ++ PG+ ++ +F ++
Sbjct: 3669 PGSTDTTLLP--ASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPG 3726
Query: 1535 -TISSEYTHSSASSPELNDSSVALSSWGQ-----QPSSGYQEENQG-NWSEQNHQESELI 1587
T ++ + S+ SS + S+ SS G P+S QG + + Q H S
Sbjct: 3727 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHT 3786
Query: 1588 TTDGQVEIVTKVKDLEKNRINEFEKSFDRKTPTFLEIWNDSVDGDSFSSL---SSPE--- 1641
T V++ + +S TPT + + G S S SSP+
Sbjct: 3787 TPSPPSTATAPVEE-----STTYHRS-PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 3840
Query: 1642 TGKYSEHS---------------GTHQESNLIASYQEKNEHDISATVQPEDARVISTSSG 1686
T S HS G+ + + L S + S T +T S
Sbjct: 3841 TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSP 3900
Query: 1687 SDDDSVG-GEESIEEEIQVANCH-VAEDESRAWDSLNESNKFLVTADPKSENIYDYLDSS 1744
+ S+G GEES Q + H S L+E + + ++ P S + S+
Sbjct: 3901 ASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRST 3960
Query: 1745 EPAENENKSNPFCDNQQSS-----PDPWTFSPLTETEMQITAVEKEKRSS-PETGTTGDV 1798
+ + F S+ + T S LTE ++ P T TT D+
Sbjct: 3961 TTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADL 4020
Query: 1799 AWQISPKASFPKNEDNSQLEM-------LGFSADST--EWWKASPQEGRLIESPFERELS 1849
+FP + ++ ++ G +ST +S + L SP LS
Sbjct: 4021 G---EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLS 4077
Query: 1850 DSSGVLEIN-SSVHQNASPWGVPVQGDIEPVETHYTNP-------FSDNHQSPFLEGNGK 1901
+ S + S SP G E T ++ P F D+ + L
Sbjct: 4078 EKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPT 4137
Query: 1902 NSHEQLWNIQPRQPDPDADKFSQLVKLDQIKEKDSREQTFVSAAGDELT----------- 1950
SH + + P + S L + TF S+ GD T
Sbjct: 4138 TSHSSQGSTEATL-SPGSTTASSL---------GQQSTTFHSSPGDTETTLLPDDTITSG 4187
Query: 1951 ---PETPTQEQCQDTMLPVCDHPDTAFTHAEEN----SCVTSNVSTNEGQETNQWEQEKS 2003
TPT + T+ EE+ S +S+ +T T E S
Sbjct: 4188 LVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVS 4247
Query: 2004 YLGEMTNSSIATENFPAVSS-------PTQLIMKPGSEWDGSTPSEDSRGTFVPDILHGN 2056
SS T +F A S+ T + PG+ P+ + V +
Sbjct: 4248 TTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSP 4307
Query: 2057 FQEGGQLASAAPDLWIDA---KKPFSLKADGENPDILTHCEHDSNSQASDSPDICHDSEA 2113
G +A P A +K + + +PD ++S S+ H
Sbjct: 4308 ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 4367
Query: 2114 KQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGR--------EFVPSNAELDSENA 2165
T S+ P V + PG E ++ S
Sbjct: 4368 SMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTET 4427
Query: 2166 TVLPPIGYQADIKGSSQPA-SHKGSP 2190
T+LP + + +S P S GSP
Sbjct: 4428 TLLPDNTTASGLLEASTPVHSSTGSP 4453
Score = 38.9 bits (89), Expect = 0.080
Identities = 259/1263 (20%), Positives = 418/1263 (33%), Gaps = 247/1263 (19%)
Query: 362 SNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPS--SVNFIENPPDLNDSNQAQVDA 419
+ S TS + ++P+S GS L GS P S S F +P +
Sbjct: 2010 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR-----------S 2058
Query: 420 NVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAVAE 479
+SP A+ SS S+ES+ S A P T PGL +S
Sbjct: 2059 PATTLSP----ASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS-------TT 2107
Query: 480 EHAWSGEHGEHFDLFNFDPAPMASGQSQQS--SHSADYSPADDFFPNSD--LSEGQLPAG 535
H+ G D + SG SQ+S SHS+ S P S LS GQ
Sbjct: 2108 SHSSPGST----DTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTT 2163
Query: 536 PEGLDGMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDES 595
G T+ + + S+ SG +VE SPR S + + ES
Sbjct: 2164 FHSSPG-STHTTLFPDSTTSSG-----IVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 2217
Query: 596 PS----PERLKNTGKRIPPTPMNSLVE----------SSPSTEEPASLYTEDMTQKATDT 641
+ P T PP+ + VE S+P+T PAS +T +
Sbjct: 2218 TAFQTHPASTHTTPS--PPSTATAPVEESTTYHRSPGSTPTTHFPAS---------STTS 2266
Query: 642 GHMGPPQTHARCSSWWGGLEIDSKNIADAWSSSEQESVF-QSPESWKEHKPSSIDRRASD 700
GH SE+ ++F SP++
Sbjct: 2267 GH------------------------------SEKSTIFHSSPDA--------------- 2281
Query: 701 SVFQPKSLEFTKSGPWESEFGQPELGSNDIQDKNEESLPFQNLPMEKSPLPNTSPQGTNH 760
S P S T SG ES + GS +I + LP ++ T
Sbjct: 2282 SGTTPSSAHSTTSGRGESTTSRISPGSTEI-----------------TTLPGSTT--TPG 2322
Query: 761 LIEDFASLWHSGRSPTAMPEPWG-NPTDDGEPAAVAPFPAWSAFGKEDHDEALKNTWNLH 819
L E + + S RSPT P GE + + S +
Sbjct: 2323 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS------------TVS 2370
Query: 820 PTSSKTPSVRDPNEWAMAKSGFAFSSSELLDNSPSEINNEAAPEIWGKKNNDSRDHIFAP 879
P S+ TP + + + + S + + + +P+ P + + + +F
Sbjct: 2371 PASTTTPGLSEESTTVYSSSP-GSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTE 2429
Query: 880 GNPSSDL-DHTWTNSKPPKEDQNGLVDPKTRGKVYEKVDSWNLFEENMKKGGSDVLVPWE 938
+ +S L + + P Q GL T + E+ ++ G + +
Sbjct: 2430 DSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTF-----PSSSGSTGTTLSPA 2484
Query: 939 DSFLSYKCSDYSASNLGEDSV--------PSPLDTNYSTSDSYTSPTF--AGDEKETEHK 988
S S + + S L S P+ + ++ YTSP A T
Sbjct: 2485 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTS 2544
Query: 989 PFAKEEGFESKDGNSTAEETDIPPQSLQQS-SRNRISS--GPGNLD---MWASPHTDNSS 1042
EE S + T P + SR+ +S PG+ D + AS T S
Sbjct: 2545 SGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPS 2604
Query: 1043 EINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYDDPSMMQ--LYNETN------RQ 1094
+ +TT + T + G ++ G+ S + + P L+ ++
Sbjct: 2605 QESTTSHSSPGSTDTALSPGSTTAL--SFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEA 2662
Query: 1095 LTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDDCSGGAAIPSDGQTE 1154
T +HSST S +T + + +ST + + A P + T
Sbjct: 2663 STRVHSSTGSPRTTLSPASSTSPGL--QGESTTFQTHPASTHTTPSPPSTATAPVEESTT 2720
Query: 1155 GYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSAPSE-HHTLNEKSGQ 1213
+ + GS P T F PAS + S S H+ + SG
Sbjct: 2721 YHRSPGSTPTTHF----------------------PASSTTSGHSEKSTIFHSSPDASGT 2758
Query: 1214 LIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPDAPAASGT 1273
+++ + R + +S + PGS+ IT LP + + T +P + T
Sbjct: 2759 TPSSAHSTTSGRGESTTSRISPGSTEIT-----TLPGSTTTPGLSEASTTFYSSPRSPTT 2813
Query: 1274 SESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHGDGQSESEKEAQGA 1333
+ S A ++ L + E T +S S + + P G + + + G+
Sbjct: 2814 TLSPASMTSLGVGE-ESTTSRSQPGSTHSTVS-----PASTTTPGLSEESTTVYSSSPGS 2867
Query: 1334 TDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEICIKSGKISSLAVTFSPQ 1393
T+ + ++ S +G+ S AS H + + S L
Sbjct: 2868 TE----------TTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGL------- 2910
Query: 1394 TEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEKHLMSQRNSGETTETSDGMNFT 1453
TE E ++ QTG+ A L D E+ +SG T T T
Sbjct: 2911 TE--------ESTAFPGSPASTQTGLPA-TLTTADLGEESTTFPSSSGSTGTTLSPARST 2961
Query: 1454 KYVSVPEKDLEKTEECNFLEPENVGGGP--PHRVPRSLDFGDVPIDSDVHVSSTCSEITK 1511
V E + + E + G P P +S F P D +S + +
Sbjct: 2962 TSGLVGESTPSRLSPSS-TETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSG 3020
Query: 1512 NLDVKGSENSLPGAGSSGNFDRDTISS------EYTHSSASSPE--LNDSSVALSSWGQQ 1563
+ + +S PG+ + F T +S +HSS S E L+ S SS GQQ
Sbjct: 3021 VSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQ 3080
Query: 1564 PSS 1566
++
Sbjct: 3081 STT 3083
Score = 37.4 bits (85), Expect = 0.23
Identities = 355/1779 (19%), Positives = 568/1779 (31%), Gaps = 309/1779 (17%)
Query: 362 SNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPS--SVNFIENPPDLNDSNQAQVDA 419
+ S TS + ++P+S GS L GS P S S F +P +
Sbjct: 3567 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR-----------S 3615
Query: 420 NVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAVAE 479
+SP A+ SS S+ES+ S A P T PGL +S
Sbjct: 3616 PATTLSP----ASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS-------TT 3664
Query: 480 EHAWSGEHGEHFDLFNFDPAPMASGQSQQS--SHSADYSPADDFFPNSD--LSEGQLPAG 535
H+ G D + SG SQ+S SHS+ S P S LS GQ
Sbjct: 3665 SHSSPGST----DTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTT 3720
Query: 536 PEGLDGMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDES 595
G T+ + + S+ SG +VE SPR S + + ES
Sbjct: 3721 FHSSPG-STHTTLFPDSTTSSG-----IVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 3774
Query: 596 PS----PERLKNTGKRIPPTPMNSLVE----------SSPSTEEPASLYTEDMTQKAT-- 639
+ P T PP+ + VE S+P+T PAS T ++K+T
Sbjct: 3775 TAFQTHPASTHTTPS--PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 3832
Query: 640 ----DTGHMGPPQTHARCSSWW---------GGLEID-----------SKNIADAWSSSE 675
D P H+ S G EI S+ +SS
Sbjct: 3833 HSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 3892
Query: 676 QESVFQSPESW-----------KEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEFGQPE 724
+ SP S +P S S + L + + S G E
Sbjct: 3893 SPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTE 3952
Query: 725 L----GSNDIQDKNEESLPFQNLPMEKSPLPNTSPQGTNHLIEDFASLWHSGRS-PTAMP 779
S + EE F + P T T+ L E+ + S S T +P
Sbjct: 3953 TTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP 4012
Query: 780 EPWGNPTDDGEPAAVAPFPAWSAFGKEDHDEAL-------KNTWNLHPTSSKTPSV-RDP 831
D GE + P + S K + L P+S++T ++ P
Sbjct: 4013 ATL-TTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP 4071
Query: 832 NEWAMAKSGFAFSSSELLDNSPSEINNEAAPEIWGKKNNDSRDHIFAPGNPSSDLDHTWT 891
++++ F +S SP + A G S H PG+ T T
Sbjct: 4072 TTPSLSEKSTTFYTS---PRSPDATLSPATTTSSGVSEESSTSH-SQPGS-------THT 4120
Query: 892 NSKPPKEDQNGLVDPKTRGKVYEKVDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSA 951
+ P +GL T S E + G + +A
Sbjct: 4121 TAFPDSTTTSGLSQEPTTSH-----SSQGSTEATLSPGST------------------TA 4157
Query: 952 SNLGEDSVPSPLDTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFESKDG-NSTAEETDI 1010
S+LG+ S T + +S T T D+ T A S ++T
Sbjct: 4158 SSLGQQS------TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASS 4211
Query: 1011 PPQSLQQSSRNRISSGPGNLDMWASPHTDNS--SEINTTHNLDENELKTEHTDGKNISME 1068
LQ+ S S P + D SP + + E++TT++ + T H + ++
Sbjct: 4212 TSTGLQEES-TTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTL- 4269
Query: 1069 DDVGESSQSSYDDPSMMQLYNETNRQLTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTAT 1128
G S +S T +HSS + TA V++ + +T+
Sbjct: 4270 ---GRSEES------------------TTVHSSPGATGTALFPTRSATSVLVGE-PTTSP 4307
Query: 1129 ISDMDNDLDWDDCSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWE 1188
IS + A+P T G SE T F Y D
Sbjct: 4308 ISSGSTET--------TALPGSTTTAGL----SEKSTTF-----------YSSPRSPDTT 4344
Query: 1189 L-PASDEHTKDSAPSEHHTLNEKSGQLIANSIWDSV----MRDKDMSSFMLPGSSHIT-- 1241
L PAS T E T + + G + + S + + +S PGS+ T
Sbjct: 4345 LSPAST--TSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLS 4402
Query: 1242 --DSEQRELPPE---IPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSD 1296
+ L PE S + + T PD ASG E+ + + T S
Sbjct: 4403 PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEAS---TPVHSSTGSPHTTLSP 4459
Query: 1297 AASLATRLENPGYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGIS 1356
A S + E+ + P+ S+ A T ++ S + S S
Sbjct: 4460 AGSTTRQGESTTFQSWPN---------SKDTTPAPPTTTSAFVE-----LSTTSHGSPSS 4505
Query: 1357 EKGQSDQELSSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQ 1416
S+ + + + S +++ A T SP ++E E +Y+ Q
Sbjct: 4506 TPTTHFSASSTTLGRSEESTTVHSSPVAT-ATTPSPARSTTSGLVE-ESTTYHSSPGSTQ 4563
Query: 1417 TGMSADNLQPKDTHEKHLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPEN 1476
T H + GE + TS S P EE +
Sbjct: 4564 T-----------MHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH-SS 4611
Query: 1477 VGGGPPHRVPRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTI 1536
G P S +S SS + T L + + + L G ++ ++
Sbjct: 4612 PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 4671
Query: 1537 SSEYTHSSASSPELNDSSVALSSWGQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIV 1596
+ S ++P L++ S S PSS + + E V
Sbjct: 4672 ETTALPGSTTTPGLSEKSTTFHS---SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 4728
Query: 1597 TKVKDLEKNRINEFEK-----SFDRKTPTFLEIWNDSVDGDSFSSLSSPETGKYSEHSGT 1651
T E+ S T T + + G S S +S + ++ S
Sbjct: 4729 TTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP 4788
Query: 1652 HQESNLI---ASYQEKNEHDISATVQPEDARVISTSSGSDDDSVGGEESIEEE-IQVANC 1707
S L+ SY + I+ T PE ST+SG ++S S + I
Sbjct: 4789 STTSALVEEPTSY-HSSPGSIATTHFPES----STTSGRSEESTASHSSPDTNGITPLPA 4843
Query: 1708 HVAEDESRAWDSLNESNKFLVTADPKSENIYDYLDSSEPAENENKSNPFCDNQQSSPDPW 1767
H + ES F ++ ++ L S+ + + + SPD
Sbjct: 4844 HFTTS-----GRIAESTTFYISPG----SMETTLASTATTPGLSAKSTILYSSSRSPDQ- 4893
Query: 1768 TFSPLTETEMQITAVEKEKRSSPETGTTGDVAWQISPKASFPKNEDNSQLEMLGFSADST 1827
T SP + T I+ S E+ T +FP + S G S +ST
Sbjct: 4894 TLSPASMTSSSISGEPTSLYSQAESTHT----------TAFPASTTTS-----GLSQEST 4938
Query: 1828 EW------WKASPQEGRLIESPFERELSDSSGVLEINSSVHQNASPWGVPVQGDIEPVET 1881
+ + + G + S F +E + S SP V G E T
Sbjct: 4939 TFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQ---PGSALSTVSPASTTVPGLSEESTT 4995
Query: 1882 HYTNPFSDNHQSPFLEGNGKNSHEQLWNIQPRQPDPDADKFSQLVKLDQIKEKDSREQTF 1941
Y++P S + F N + H Q P PD+ F+ V + D +++
Sbjct: 4996 FYSSPGS-TETTAFSHSNTMSIHS-----QQSTPFPDSPGFTHTVLPATLTTTDIGQEST 5049
Query: 1942 VSAAGDELTPETPTQEQCQDTMLPVCDHPDTAFTHAEENSCV---TSNVSTNEGQETNQW 1998
+ + T TP + T + P T + S+ ++ +E+ +
Sbjct: 5050 AFHSSSDATGTTPL--PARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTF 5107
Query: 1999 EQEKSYLGEMTNSSIATENFPAVSSPTQLIMKPGSEWDG 2037
S+ T++ ++TE+ ++ + + G W+G
Sbjct: 5108 HTSPSF----TSTIVSTESLETLAPG---LCQEGQIWNG 5139
Score = 33.5 bits (75), Expect = 3.3
Identities = 81/319 (25%), Positives = 113/319 (35%), Gaps = 60/319 (18%)
Query: 362 SNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPS--SVNFIENPPDLNDSNQAQVDA 419
+ S TS + ++P+S GS L GS P S S F +P +
Sbjct: 927 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPR-----------S 975
Query: 420 NVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAVAE 479
+SP A+ SS S+ES+ S A P T PGL +S
Sbjct: 976 PATTLSP----ASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHS-------TT 1024
Query: 480 EHAWSGEHGEHFDLFNFDPAPMASGQSQQS--SHSADYSPADDFFPNSD--LSEGQLPAG 535
H+ G D + SG SQ+S SHS+ S P S LS GQ
Sbjct: 1025 SHSSPGST----DTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTT 1080
Query: 536 PEGLDGMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDES 595
G T+ + + S+ SG +VE SPR S + + ES
Sbjct: 1081 FHSNPG-STHTTLFPDSTTSSG-----IVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 1134
Query: 596 PS----PERLKNTGKRIPPTPMNSLVE----------SSPSTEEPASLYTEDMTQKAT-- 639
+ P T PP+ + VE S+P+T PAS T ++K+T
Sbjct: 1135 TAFQTHPASTHTTPS--PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 1192
Query: 640 ----DTGHMGPPQTHARCS 654
D P H+ S
Sbjct: 1193 HSSPDASGTTPSSAHSTTS 1211
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 46.6 bits (109), Expect = 4e-04
Identities = 67/319 (21%), Positives = 120/319 (37%), Gaps = 51/319 (15%)
Query: 1052 ENELKTEHTDGKNISMEDDVGESSQSSYDDPSMMQLYNETNRQLTLLHSSTNSRQTAPDS 1111
EN + G S +D+ G+S Q PS +L+ + + H S + +
Sbjct: 32 ENAASGSNASGSE-SDQDERGDSGQ-----PSNKELFGDDSEDEGASHHSGSDNHSERSD 85
Query: 1112 LDLWNRVILEDTQSTATISDMDNDLDWDDCSGGAAIPSDGQTEGYMAEGSEPETRFTVRQ 1171
NR ++++ DND D G+ P+D + EG+ ++G + +
Sbjct: 86 ----NR-----SEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSE 136
Query: 1172 L-----EPWGLEYQEANQVDWELPASDEHTKDSAPSEHHTLNEKSGQLIANSIWDSVMRD 1226
E WG E + D ++ SD+ + E N + + N+ D R
Sbjct: 137 KAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNT--DDEERP 194
Query: 1227 KDMSSFMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQ 1286
+ ++D E+++L E AN D + P AS + + +
Sbjct: 195 Q------------LSDDERQQLSEE---EKANSDD----ERPVASDNDDEKQ-----NSD 230
Query: 1287 DTERETLQSDAASLATRLENPGYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIA 1346
D E+ L + + E P D H D + E + +++ A RG E+EV+
Sbjct: 231 DEEQPQLSDEEKMQNSDDERP---QASDEEHRHSDDEEEQDHKSESA--RGSDSEDEVLR 285
Query: 1347 SGVENASGISEKGQSDQEL 1365
+NA + SD E+
Sbjct: 286 MKRKNAIASDSEADSDTEV 304
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor
[Homo sapiens]
Length = 513
Score = 45.8 bits (107), Expect = 7e-04
Identities = 112/525 (21%), Positives = 204/525 (38%), Gaps = 99/525 (18%)
Query: 868 KNNDSRD------HIFAPGNPSSDLDHTWTNSKPPKEDQNGLVDPKTRGKVYEKVDS--- 918
+NN+S D H+ P + + SK E+Q DP + E + S
Sbjct: 23 QNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQAN-EDPSDSTQSEEGLGSDDH 81
Query: 919 ---WNL---FEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDS 972
+ L F + KGG D +DS D + + +DS P P D +
Sbjct: 82 QYIYRLAGGFSRSTGKGGDDKDDDEDDS------GDDTFGD--DDSGPGPKDRQEGGNSR 133
Query: 973 YTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSRNRISSGPGNLDM 1032
G +++++ A EE + G +A++T +S + + +R+ S P D
Sbjct: 134 L------GSDEDSDDTIQASEES--APQGQDSAQDTT--SESRELDNEDRVDSKPEGGDS 183
Query: 1033 WASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYDDPSMMQLYNETN 1092
++ SE + + E + H DG + DD G S DDP ++ +
Sbjct: 184 TQ----ESESEEHWVGGGSDGE--SSHGDGSEL---DDEGMQS----DDPESIRSERGNS 230
Query: 1093 RQ----LTLLHSSTNSRQTAPDSLDLWNRVILEDTQST----ATISDMDNDLDWDDCSGG 1144
R + S NS Q ++ D +LE + IS+ D+ + DD +
Sbjct: 231 RMNSAGMKSKESGENSEQA--NTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTM 288
Query: 1145 AAIPSDGQTEGYMAEG--SEP--ETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSA 1200
+ SD + S+P +++ ++ L +E+ VD S E ++++
Sbjct: 289 EEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGP---SSESSQEAN 345
Query: 1201 PSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVK 1260
S +E ++++ S D+ P +S++ D E + E SH+ +
Sbjct: 346 LSSQENSSESQEEVVSESRGDNPD----------PTTSYVEDQEDSDSSEEDSSHTLSHS 395
Query: 1261 DTHSPDAPAASGTSES-----EALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDP 1315
+ S + A S +SES E+ S D+ + +E LQS ++S ++ E
Sbjct: 396 KSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSE---------- 445
Query: 1316 WKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQ 1360
+S SE++ + D E+ ++ E+ S E GQ
Sbjct: 446 -------ESHSEEDDSDSQDSSRSKED---SNSTESKSSSEEDGQ 480
Score = 35.8 bits (81), Expect = 0.67
Identities = 85/388 (21%), Positives = 143/388 (36%), Gaps = 40/388 (10%)
Query: 1198 DSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEI----- 1252
DS P + +L ++ D ++ + S+ S+ T SE REL E
Sbjct: 118 DSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSK 177
Query: 1253 PSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPH 1312
P + +++ S + G S+ SH D + + E +QSD + R E +
Sbjct: 178 PEGGDSTQESESEEHWVGGG---SDGESSHGDGSELDDEGMQSDDPE-SIRSERGNSRMN 233
Query: 1313 PDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASE 1372
K G++ + Q D G E + + S ISE+ + + +
Sbjct: 234 SAGMKSKESGENSEQANTQ---DSGGSQLLEHPSRKIFRKSRISEEDDRSELDDN---NT 287
Query: 1373 HQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEK 1432
+E+ S + S+ T Q + E+ NL + Q + D + + E
Sbjct: 288 MEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQ---NVDGPSSESSQEA 344
Query: 1433 HLMSQRNSGETTET----SDGMN---FTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRV 1485
+L SQ NS E+ E S G N T YV ++D + +EE + H +
Sbjct: 345 NLSSQENSSESQEEVVSESRGDNPDPTTSYVE-DQEDSDSSEEDS-----------SHTL 392
Query: 1486 PRSL-DFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSS 1544
S + + DS+ S SE ++ + ENS G + SE +HS
Sbjct: 393 SHSKSESREEQADSESSESLNFSE--ESPESPEDENSSSQEGLQSHSSSAESQSEESHSE 450
Query: 1545 ASSPELNDSSVALSSWGQQPSSGYQEEN 1572
+ DSS + S EE+
Sbjct: 451 EDDSDSQDSSRSKEDSNSTESKSSSEED 478
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 45.1 bits (105), Expect = 0.001
Identities = 89/422 (21%), Positives = 168/422 (39%), Gaps = 75/422 (17%)
Query: 956 EDSVPSPLDTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSL 1015
+DS P P D + G +++++ A EE + G +A++T +S
Sbjct: 101 DDSGPGPKDRQEGGNSRL------GSDEDSDDTIQASEES--APQGQDSAQDTT--SESR 150
Query: 1016 QQSSRNRISSGPGNLDMWASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESS 1075
+ + +R+ S P D ++ SE + + E + H DG + DD G S
Sbjct: 151 ELDNEDRVDSKPEGGDSTQ----ESESEEHWVGGGSDGE--SSHGDGSEL---DDEGMQS 201
Query: 1076 QSSYDDPSMMQLYNETNRQ----LTLLHSSTNSRQTAPDSLDLWNRVILEDTQST----A 1127
DDP ++ +R + S NS Q ++ D +LE +
Sbjct: 202 ----DDPESIRSERGNSRMNSAGMKSKESGENSEQA--NTQDSGGSQLLEHPSRKIFRKS 255
Query: 1128 TISDMDNDLDWDDCSGGAAIPSDGQTEGYMAEG--SEP--ETRFTVRQLEPWGLEYQEAN 1183
IS+ D+ + DD + + SD + S+P +++ ++ L +E+
Sbjct: 256 RISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQ 315
Query: 1184 QVDWELPASDEHTKDSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDS 1243
VD S E ++++ S +E ++++ S D+ P +S++ D
Sbjct: 316 NVDGP---SSESSQEANLSSQENSSESQEEVVSESRGDNPD----------PTTSYVEDQ 362
Query: 1244 EQRELPPEIPSHSANVKDTHSPDAPAASGTSES-----EALISHLDKQDTERETLQSDAA 1298
E + E SH+ + + S + A S +SES E+ S D+ + +E LQS ++
Sbjct: 363 EDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSS 422
Query: 1299 SLATRLENPGYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEK 1358
S ++ E +S SE++ + D E+ ++ E+ S E
Sbjct: 423 SAESQSE-----------------ESHSEEDDSDSQDSSRSKED---SNSTESKSSSEED 462
Query: 1359 GQ 1360
GQ
Sbjct: 463 GQ 464
Score = 35.8 bits (81), Expect = 0.67
Identities = 85/388 (21%), Positives = 143/388 (36%), Gaps = 40/388 (10%)
Query: 1198 DSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEI----- 1252
DS P + +L ++ D ++ + S+ S+ T SE REL E
Sbjct: 102 DSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSK 161
Query: 1253 PSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPH 1312
P + +++ S + G S+ SH D + + E +QSD + R E +
Sbjct: 162 PEGGDSTQESESEEHWVGGG---SDGESSHGDGSELDDEGMQSDDPE-SIRSERGNSRMN 217
Query: 1313 PDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASE 1372
K G++ + Q D G E + + S ISE+ + + +
Sbjct: 218 SAGMKSKESGENSEQANTQ---DSGGSQLLEHPSRKIFRKSRISEEDDRSELDDN---NT 271
Query: 1373 HQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEK 1432
+E+ S + S+ T Q + E+ NL + Q + D + + E
Sbjct: 272 MEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQ---NVDGPSSESSQEA 328
Query: 1433 HLMSQRNSGETTET----SDGMN---FTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRV 1485
+L SQ NS E+ E S G N T YV ++D + +EE + H +
Sbjct: 329 NLSSQENSSESQEEVVSESRGDNPDPTTSYVE-DQEDSDSSEEDS-----------SHTL 376
Query: 1486 PRSL-DFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSS 1544
S + + DS+ S SE ++ + ENS G + SE +HS
Sbjct: 377 SHSKSESREEQADSESSESLNFSE--ESPESPEDENSSSQEGLQSHSSSAESQSEESHSE 434
Query: 1545 ASSPELNDSSVALSSWGQQPSSGYQEEN 1572
+ DSS + S EE+
Sbjct: 435 EDDSDSQDSSRSKEDSNSTESKSSSEED 462
>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapiens]
Length = 729
Score = 44.3 bits (103), Expect = 0.002
Identities = 100/432 (23%), Positives = 149/432 (34%), Gaps = 49/432 (11%)
Query: 2179 GSSQPASHKGSPEPSEINGDNSTGLQVSEKGASPDMAPILEPVDRR--IPRI--ENVATS 2234
GSS P + + +P+ S+ V A P A P RR I R+ + AT
Sbjct: 310 GSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATE 369
Query: 2235 IFVTHQEPTPEGDGSWISDS---FSPESQPGARALFDGDPHLSTENPALVPDALLASDTC 2291
EP P +G S F P+ + L D P A D
Sbjct: 370 AAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTP---------------ARDEK 414
Query: 2292 LDISEAAFDHSFSDASGLNTS---TGTIDDMSKLTLSEGHPETPVDGDLGKQDICSSEAS 2348
++AA S SD L + G DD+ G P P G + QDI S
Sbjct: 415 KVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPA-GPVPSQDITLSSEE 473
Query: 2349 WGDFEYDVMGQNIDEDLLREPE---HFLYGGDPPLEEDSLKQSLAPYTPPFDLSYLTEPA 2405
+ G EPE + P + + P+ P +S T P
Sbjct: 474 EAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPW--PGGVSVRTGPE 531
Query: 2406 QSAETI----------EEAGSPEDESLGCRAAEIVLSALPDRRSEGNQAETKNRLPGSQL 2455
+ + T E+A S E + G AA+++ + D E ++T+ R
Sbjct: 532 KRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADD--- 588
Query: 2456 AVLHIREDPESVYLPVGAGSNILSPSNVDWEVETDNSDLPAGGDIGPPNGASKEISELEE 2515
+R+DP V + P + +D G +G KE SE +
Sbjct: 589 --FPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFG-LGLEEAGPKESSEEGK 645
Query: 2516 EKTIPTKEPEQIKSEYK-EERCTEKNEDRHALHMDYILVNRE-ENSHSKPETCEERESIA 2573
E P+KE ++ K + K EE K + +H D E +P ER +
Sbjct: 646 EGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAAD 705
Query: 2574 ELELYVGSKETG 2585
ELE ++G G
Sbjct: 706 ELEAFLGGGAPG 717
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 43.9 bits (102), Expect = 0.002
Identities = 131/655 (20%), Positives = 236/655 (36%), Gaps = 99/655 (15%)
Query: 1197 KDSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSH--ITDSEQRELPPEIPS 1254
K SAP E KS IA + + K + P + + + LP E
Sbjct: 1253 KTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK 1312
Query: 1255 HSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPD 1314
+ +K+ P P + + E +K+D + +T S L + GY
Sbjct: 1313 TTKTIKE--QPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGY----- 1365
Query: 1315 PWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQ 1374
DG S S E +E+ I G++ S E S S L E
Sbjct: 1366 ----SSDGISSSLGEIPSLIPT----DEKDILKGLKKDSFSQESSPSSP--SDLAKLEST 1415
Query: 1375 EICIKSGKISSLAVTFSPQTEEPEEVL----EYEEGSYNLDSRDVQTGMSADNLQP---- 1426
+ I + S+LA S + +P EV + +E + +L S ++ +S + ++
Sbjct: 1416 VLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSL-SETLEITISEEEIKESQEE 1474
Query: 1427 -KDTHEKHLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRV 1485
KDT +K SQ++ + + + F ++ + + EE + E EN P +
Sbjct: 1475 RKDTFKKD--SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESS--ESEN---SPVPQR 1527
Query: 1486 PRSLDFGDVPIDSDVHVSSTCS------------EITKNLDVKGSE------NSLPGAGS 1527
R G D S S E++ + D GSE N L S
Sbjct: 1528 KRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISS 1587
Query: 1528 SGNFDRD---------TISSEYTHSSASSPELNDSSVALSSWGQQPSSGYQEENQGNWSE 1578
S + T + SS +++ + SW + + E + + E
Sbjct: 1588 STESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRE 1647
Query: 1579 QNHQES-ELITTDG-------QVEIVTKVKDLEKNRINEFEKS--FDRKTPTFLEIWNDS 1628
QES EL+ T G +E+ + + D ++ + S FD + +E DS
Sbjct: 1648 TKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDS 1707
Query: 1629 VD----GDSFSSLS----SPETGKYSEHSGTHQESNLIASYQEKNEHDISATVQPEDARV 1680
+ G+ SSL +P T S S + + + +++ A +P +
Sbjct: 1708 PEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLL 1767
Query: 1681 ISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPKSE----- 1735
+ S+++ + EE + +E Q + + + ++ ++ +K + A + E
Sbjct: 1768 PTIEDSSEEEELREEEELLKE-QEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP 1826
Query: 1736 --NIYDYLDSS------EPAENENKSNPFCDNQ----QSSPDPWTFSPLTETEMQ 1778
N+ D+S + AE E C +S P+ + SP E+Q
Sbjct: 1827 PSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQ 1881
Score = 36.6 bits (83), Expect = 0.39
Identities = 58/250 (23%), Positives = 89/250 (35%), Gaps = 48/250 (19%)
Query: 498 PAPMASGQSQQSSHSADYSPADDFFPNSDLSEGQLPAGPEGLDGMGTNMSNYSSSSLLSG 557
P P + + Q + + +D SD S Q P P+GL G YSS + S
Sbjct: 1321 PQPPCTAKPDQVEPGKEKTEKED--DKSDTSSSQQPKSPQGLSDTG-----YSSDGISSS 1373
Query: 558 AGK-DSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSPERLKNTGKRIPPTPMNSL 616
G+ SL+ DE+ + + L F + SPS P+ + L
Sbjct: 1374 LGEIPSLIPTDEKDIL----------KGLKKDSFSQESSPS-----------SPSDLAKL 1412
Query: 617 VESSPS-TEEPASLYTEDMTQKATDTGHMGPPQTHARCSSWWGGLEIDSKNIADAWSSSE 675
+ S E AS ++ ++K T + P Q K+ S SE
Sbjct: 1413 ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQ---------------PKDQEKTQSLSE 1457
Query: 676 QESVFQSPESWKEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEFGQPELGSNDIQDKNE 735
+ S E KE + D DS + + +K +SEF + D E
Sbjct: 1458 TLEITISEEEIKESQEERKDTFKKDS---QQDIPSSKDHKEKSEFVDDITTRREPYDSVE 1514
Query: 736 ESLPFQNLPM 745
ES +N P+
Sbjct: 1515 ESSESENSPV 1524
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 43.9 bits (102), Expect = 0.002
Identities = 131/655 (20%), Positives = 236/655 (36%), Gaps = 99/655 (15%)
Query: 1197 KDSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSH--ITDSEQRELPPEIPS 1254
K SAP E KS IA + + K + P + + + LP E
Sbjct: 1253 KTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK 1312
Query: 1255 HSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPD 1314
+ +K+ P P + + E +K+D + +T S L + GY
Sbjct: 1313 TTKTIKE--QPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGY----- 1365
Query: 1315 PWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQ 1374
DG S S E +E+ I G++ S E S S L E
Sbjct: 1366 ----SSDGISSSLGEIPSLIPT----DEKDILKGLKKDSFSQESSPSSP--SDLAKLEST 1415
Query: 1375 EICIKSGKISSLAVTFSPQTEEPEEVL----EYEEGSYNLDSRDVQTGMSADNLQP---- 1426
+ I + S+LA S + +P EV + +E + +L S ++ +S + ++
Sbjct: 1416 VLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSL-SETLEITISEEEIKESQEE 1474
Query: 1427 -KDTHEKHLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRV 1485
KDT +K SQ++ + + + F ++ + + EE + E EN P +
Sbjct: 1475 RKDTFKKD--SQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESS--ESEN---SPVPQR 1527
Query: 1486 PRSLDFGDVPIDSDVHVSSTCS------------EITKNLDVKGSE------NSLPGAGS 1527
R G D S S E++ + D GSE N L S
Sbjct: 1528 KRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISS 1587
Query: 1528 SGNFDRD---------TISSEYTHSSASSPELNDSSVALSSWGQQPSSGYQEENQGNWSE 1578
S + T + SS +++ + SW + + E + + E
Sbjct: 1588 STESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRE 1647
Query: 1579 QNHQES-ELITTDG-------QVEIVTKVKDLEKNRINEFEKS--FDRKTPTFLEIWNDS 1628
QES EL+ T G +E+ + + D ++ + S FD + +E DS
Sbjct: 1648 TKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDS 1707
Query: 1629 VD----GDSFSSLS----SPETGKYSEHSGTHQESNLIASYQEKNEHDISATVQPEDARV 1680
+ G+ SSL +P T S S + + + +++ A +P +
Sbjct: 1708 PEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLL 1767
Query: 1681 ISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPKSE----- 1735
+ S+++ + EE + +E Q + + + ++ ++ +K + A + E
Sbjct: 1768 PTIEDSSEEEELREEEELLKE-QEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTP 1826
Query: 1736 --NIYDYLDSS------EPAENENKSNPFCDNQ----QSSPDPWTFSPLTETEMQ 1778
N+ D+S + AE E C +S P+ + SP E+Q
Sbjct: 1827 PSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQ 1881
Score = 36.6 bits (83), Expect = 0.39
Identities = 58/250 (23%), Positives = 89/250 (35%), Gaps = 48/250 (19%)
Query: 498 PAPMASGQSQQSSHSADYSPADDFFPNSDLSEGQLPAGPEGLDGMGTNMSNYSSSSLLSG 557
P P + + Q + + +D SD S Q P P+GL G YSS + S
Sbjct: 1321 PQPPCTAKPDQVEPGKEKTEKED--DKSDTSSSQQPKSPQGLSDTG-----YSSDGISSS 1373
Query: 558 AGK-DSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSPERLKNTGKRIPPTPMNSL 616
G+ SL+ DE+ + + L F + SPS P+ + L
Sbjct: 1374 LGEIPSLIPTDEKDIL----------KGLKKDSFSQESSPS-----------SPSDLAKL 1412
Query: 617 VESSPS-TEEPASLYTEDMTQKATDTGHMGPPQTHARCSSWWGGLEIDSKNIADAWSSSE 675
+ S E AS ++ ++K T + P Q K+ S SE
Sbjct: 1413 ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQ---------------PKDQEKTQSLSE 1457
Query: 676 QESVFQSPESWKEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEFGQPELGSNDIQDKNE 735
+ S E KE + D DS + + +K +SEF + D E
Sbjct: 1458 TLEITISEEEIKESQEERKDTFKKDS---QQDIPSSKDHKEKSEFVDDITTRREPYDSVE 1514
Query: 736 ESLPFQNLPM 745
ES +N P+
Sbjct: 1515 ESSESENSPV 1524
>gi|111607441 hypothetical protein LOC400506 [Homo sapiens]
Length = 458
Score = 43.5 bits (101), Expect = 0.003
Identities = 48/214 (22%), Positives = 81/214 (37%), Gaps = 29/214 (13%)
Query: 1159 EGSEPETRFTVRQLEPWGLEYQEANQV---------DWELPASDEHTKDSAPSEHHTLNE 1209
+G++ T F+V+ +PW E +EA V D E A + K +P EH+ +
Sbjct: 156 KGAQDPTAFSVQ--DPWFCEAREARDVGDTCSVGKKDEEQAALGQKRKRKSPREHNGKVK 213
Query: 1210 KSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPDAPA 1269
K ++ LPG H S E P S VK +P+
Sbjct: 214 KKKKI-------------HQEGDALPG--HSKPSRSMESSPRKGSKKKPVK-VEAPEYIP 257
Query: 1270 ASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHGDGQSESEKE 1329
S ++ A K+ E+ ++ A + + DPWK D E E
Sbjct: 258 ISDDPKASAKKKMKSKKKVEQPVIEEPALKRKKKKKRKESGVAGDPWKEETDTDLEVVLE 317
Query: 1330 AQGATDRGHLDE--EEVIASGVENASGISEKGQS 1361
+G D H+D+ + + ++ SG +E ++
Sbjct: 318 KKGNMDEAHIDQVRRKALQEEIDRESGKTEASET 351
>gi|151301098 zinc finger, DBF-type containing 2 [Homo sapiens]
Length = 2354
Score = 42.0 bits (97), Expect = 0.009
Identities = 84/412 (20%), Positives = 146/412 (35%), Gaps = 93/412 (22%)
Query: 1251 EIPSHSANVKD-THSPDAPAASGTSESEALISHLDKQDTER------ETLQSDAASLATR 1303
E+ S+ + + T D P S T +S HLD + ER E+ +SD++ +
Sbjct: 739 EVRSYDCSSSELTFDSDPPLLSVTEQS-----HLDAEGKERHIDLEDESCESDSSEITFD 793
Query: 1304 LENPGYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQ 1363
+ P Y P + +EE V N S +SE D
Sbjct: 794 SDIPLYSVIDQP-------------------EVAVYEEETVDLESKSNESCVSEI-TFDS 833
Query: 1364 ELSSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADN 1423
++ ++H E+ +K + + +EP + L S ++
Sbjct: 834 DIPLHSGNDHPEVAVKEVIQKEEYIHLERKNDEPSGSEISSDSHAPLHSVTNSPEVAVKK 893
Query: 1424 LQPKDTHEKHLMSQRNSGETTETSDGMNF-----TKYVSVPEKDLE-KTEECNFLEPENV 1477
L P+ + HL ++ N +E S N T P K++ T+E +LE ++V
Sbjct: 894 LNPQKEEQVHLENKENEPIDSEVSLDYNIIFHSVTGRSEDPIKEISLHTKEHMYLENKSV 953
Query: 1478 GGGPPHRVPRSLDFGDVPIDSDVH-----VSSTCSEITKNLDVKGSENSLPGAGSSGNFD 1532
SLD DVP+ + H V T + K+ + +G G+ +S
Sbjct: 954 -------FETSLD-SDVPLQAATHKPEVIVKETWLQREKHAEFQGRSTEFSGSKTS---- 1001
Query: 1533 RDTISSEYTHSSASSPELN--------------------------DSSVALSSWGQQPSS 1566
+ S H S + P++ DS+V S QP
Sbjct: 1002 ---LDSGVPHYSVTEPQVAVNKINRKKQYVLENKNDKCSGSEIILDSNVPPQSMTDQPQL 1058
Query: 1567 GYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLE---------KNRINE 1609
+ +E N ++N + + T ++ VK ++ KN+INE
Sbjct: 1059 AFLKEKHVNLKDKNSKSGDSKITFDSEQLQEAVKKIDQWKEEVIGLKNKINE 1110
>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
Length = 935
Score = 41.6 bits (96), Expect = 0.012
Identities = 65/316 (20%), Positives = 120/316 (37%), Gaps = 29/316 (9%)
Query: 1248 LPPEIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENP 1307
LPPE+ ++ +P +P++S + + ++I D +E + S + +NP
Sbjct: 109 LPPELAGVVEEPEEDAAPASPSSSVVNPASSVI------DMSQENTRKPNVSPEKQRKNP 162
Query: 1308 GYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENAS----GISEKGQSDQ 1363
F +GH Q+++E+ G T +E+ ++ E ++ I + +S Q
Sbjct: 163 --FNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQ 220
Query: 1364 ELSSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADN 1423
L L S +I K + + ++ + + +L +R G+ N
Sbjct: 221 TLPGL--SNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTD-SLKARGAPRGILKRN 277
Query: 1424 LQPKDTHEKHLMSQRNSGETTE-TSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPP 1482
T + L N ++ S G+ + +S E LE N LEP
Sbjct: 278 SSSSSTDSETLRYNHNFEPKSKIVSPGLTIHERISEKEHSLEDNSSPNSLEPLK------ 331
Query: 1483 HRVPRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYT- 1541
V S ++P + E + L+ +N + AG + F D S+Y
Sbjct: 332 -HVRFSAVKDELPQSPGLIHGREVGEFSV-LESDRLKNGMEDAGDTEEFQSDPKPSQYRK 389
Query: 1542 ----HSSASSPELNDS 1553
H S SSP ++ S
Sbjct: 390 PSLFHQSTSSPYVSKS 405
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 40.8 bits (94), Expect = 0.021
Identities = 49/213 (23%), Positives = 86/213 (40%), Gaps = 20/213 (9%)
Query: 1600 KDLEKNRINEFEKSFDRKTPTFLEI--WNDSVDGDSFSSLSSPETGKYSEHSGTHQESNL 1657
KD + ++ + + K +LE+ W + S ++ E K +G ++ N
Sbjct: 612 KDRDHFQLGTLSHTLNIKATGYLELSNWPEVAPDPSVRNVEVIELAKEWTPAGKAKQENS 671
Query: 1658 IASYQEKNEHDISATVQPEDARVISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAW 1717
+ ++E + ED+ S+ S S+ S GE+ E +N +ED S
Sbjct: 672 AKKFYSESEEE-------EDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQ 724
Query: 1718 DSLNE-----SNKFLVTADPKSENIYDYLDSSEPAENENKSNPFCDNQQSSPDPWTFS-- 1770
DS + NK + K++ D D + E S+ D S D + S
Sbjct: 725 DSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSES 784
Query: 1771 ---PLTETEMQITAVEKEKRSSPE-TGTTGDVA 1799
P +E+E + EKEK++ + T T DV+
Sbjct: 785 ESEPESESESRRVTKEKEKKTKQDRTPLTKDVS 817
Score = 33.5 bits (75), Expect = 3.3
Identities = 42/235 (17%), Positives = 87/235 (37%), Gaps = 16/235 (6%)
Query: 925 NMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTFAGDEKE 984
N+K G L W + + L ++ P+ +++ + S + ++
Sbjct: 627 NIKATGYLELSNWPEVAPDPSVRNVEVIELAKEWTPAGKAKQENSAKKFYSESEEEEDSS 686
Query: 985 TEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSRNRISSGPGNLDMWASPHTDNSSEI 1044
E G ES + + EE D S + SS + S + S +
Sbjct: 687 DSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDS------------ESGRESGL 734
Query: 1045 NTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYDDPSMMQLYNETNRQLTLLHSSTNS 1104
N +D ++ E++ ++S SS D+ S ++ + + + S + S
Sbjct: 735 ENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESES 794
Query: 1105 RQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDDCSGGAAIPSDGQTEGYMAE 1159
R+ + + + T T +S +D D D++ S A+P+ + MA+
Sbjct: 795 RRVTKEK---EKKTKQDRTPLTKDVSLLDLD-DFNPVSTPVALPTPALSPSLMAD 845
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 40.4 bits (93), Expect = 0.027
Identities = 85/377 (22%), Positives = 129/377 (34%), Gaps = 54/377 (14%)
Query: 2102 SDSPDICHDSEAKQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGREFVPSNAELD 2161
SDS + CH E K+ +++ + ES E C +P I E PI V S+ + D
Sbjct: 81 SDSDEECHTHEEKKAKLLEINS----DDESPECCHVKPAIQEPPI-------VISDDDND 129
Query: 2162 SENATVLPPIGYQADIKGSSQPASHKGSPEPSEINGDNSTGLQVSEKGASPDMAPILEPV 2221
+N L + S + + + SE DNS + + + AP
Sbjct: 130 DDNGNDL-----EVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD 184
Query: 2222 DRRIPRIENVATSIFVTHQEPTPEGDGSWISDSFSPESQPGARALFDGDPHLSTENPALV 2281
D +P + +S + D S + D S +S + D D + + +
Sbjct: 185 DSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEA 244
Query: 2282 PDALL----ASDTCLDISEAAFDHS------FSDASGLNTSTGTIDDMSKLTLSEGHPET 2331
PD A D D SEA D S + S + DD S E
Sbjct: 245 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEA 304
Query: 2332 PVDGDLGKQDICSSEASWGDFEYDVMGQNIDEDLLREP-EHFLYGGDPPLEEDSLKQSLA 2390
P D K D D + DV N D+ + P E G +E+ L ++ A
Sbjct: 305 PDD----KSDDSDVPEDKSD-DSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAA 359
Query: 2391 PYT-------------------PPFDLSYLTEPAQSAETIEEAGSPEDESLGCRAAEIVL 2431
+ PP D E ++ EE +P E G R ++
Sbjct: 360 AVSQHDSSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKT 419
Query: 2432 SALPDRRSEGNQAETKN 2448
P R+ Q +TKN
Sbjct: 420 IVEPPRK---RQTKTKN 433
Score = 35.8 bits (81), Expect = 0.67
Identities = 39/189 (20%), Positives = 75/189 (39%), Gaps = 17/189 (8%)
Query: 2686 LALEEASGPVSQSQKSKSRGRAGPDAVTLQAVTHDNEWEMLSPQPVQKNMIPDTEMEEET 2745
L ++ SG S S S +R A ++ + D++ E + + + ++ +E
Sbjct: 50 LNVQSRSGDTSGS--SVARRAPKRQASSVVVIDSDSDEECHTHEEKKAKLLEINSDDESP 107
Query: 2746 EFLELGTRISRPNGLLSEDVGMDIPFEEGVLSPSAADMRPEPPNSLDLNDTHPRRIKLTA 2805
E + I P ++S+D D + D+ NS D A
Sbjct: 108 ECCHVKPAIQEPPIVISDDDNDD---------DNGNDLEVPDDNSDDSEAPDDNSDDSEA 158
Query: 2806 PNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHDPTANKDSGQESE 2865
P+ D S+ S DDN D + D N D+ D PD+ +S + + + + D +
Sbjct: 159 PD-----DNSDDSEAPDDNSDDSEAPDDNSDDSDVPDD-NSDDSSDDNSDDSSDDNSDDS 212
Query: 2866 SIPEYTAEE 2874
+P+ +++
Sbjct: 213 DVPDDKSDD 221
Score = 34.3 bits (77), Expect = 2.0
Identities = 46/214 (21%), Positives = 82/214 (38%), Gaps = 34/214 (15%)
Query: 2036 DGSTPSEDSRGTFVPDILHGNFQEGGQLASAAPDLWIDAKKPFSLKADGENPDIL---TH 2092
D P + S + VPD + + A D D++ P D E PD +
Sbjct: 221 DSDVPDDSSDDSDVPD-------DSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 273
Query: 2093 CEHDSNSQASDSPDICHDSEAKQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGRE 2152
DS+ + S D DSEA ++ A P+ +S + + E + D+ + + +
Sbjct: 274 APDDSSDDSEASDDSSDDSEASDDSSDDSEA---PDDKSDDSDVPEDKSDDSDVPDDNSD 330
Query: 2153 --FVPSNAELDSENATVLPPIGYQADIKGSSQPASHKGSPEPSEINGDNSTGLQVSEKGA 2210
VP AE + +D + + A+ + S+ G+ G +S+ +
Sbjct: 331 DLEVPVPAEDLCNEGQI------ASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPS 384
Query: 2211 SPDMAPILEPVDRRIPRIENVATSIFVTHQEPTP 2244
P+ P E +R++P T +EP P
Sbjct: 385 DPEANP--EVSERKLP-----------TEEEPAP 405
Score = 33.5 bits (75), Expect = 3.3
Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 2813 DQSEGSILSDDNLDSPDEIDINVDELDTP----DEADSFEYTGHDPTANKDSGQESESIP 2868
D S+ S SDDN D D D D+ D P D++D + + D A DS +SE+
Sbjct: 199 DNSDDS--SDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPD 256
Query: 2869 EYTAEEEREDN 2879
+ + + E D+
Sbjct: 257 DSSDDSEAPDD 267
Score = 33.1 bits (74), Expect = 4.4
Identities = 67/289 (23%), Positives = 113/289 (39%), Gaps = 33/289 (11%)
Query: 363 NSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPDLNDSNQAQVDANVD 422
NS SS + S+ + S + + D + S + + P D +D ++A D++ D
Sbjct: 192 NSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDD 251
Query: 423 LVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAVAEEHA 482
+PD S E+ SDDS + + DS + +E
Sbjct: 252 SEAPD-------DSSDDSEAPDDSSDDSEAPDDSSD--------DSEASDDSSDDSEASD 296
Query: 483 WSGEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDF---FPNSDL-SEGQLPAGPEG 538
S + E D D + + +S S D S DD P DL +EGQ+ + E
Sbjct: 297 DSSDDSEAPD-DKSDDSDVPEDKSDDSDVPDDNS--DDLEVPVPAEDLCNEGQIASDEEE 353
Query: 539 LDGMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSP 598
L +S + SS AG+ L E+ + ++ + SER L +E P+P
Sbjct: 354 LVEAAAAVSQHDSS---DDAGEQDLGENLSKPPSDPEANPEVSERKLPT-----EEEPAP 405
Query: 599 ERLKNTGKRIPPTPMNSLVESSPSTEEPASLYTEDMTQKATDTGHMGPP 647
++ +GKR T ++VE + E ++ T T ++ P
Sbjct: 406 V-VEQSGKRKSKT--KTIVEPPRKRQTKTKNIVEPPRKRQTKTKNIVEP 451
Score = 33.1 bits (74), Expect = 4.4
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 4/71 (5%)
Query: 2813 DQSEGSILSDDNLDSPDEIDINVDELDTP----DEADSFEYTGHDPTANKDSGQESESIP 2868
D+S+ S + DD+ D D D + D+ + P D++++ + + D A DS +SE+
Sbjct: 217 DKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 276
Query: 2869 EYTAEEEREDN 2879
+ + + E D+
Sbjct: 277 DSSDDSEASDD 287
Score = 32.7 bits (73), Expect = 5.7
Identities = 18/72 (25%), Positives = 38/72 (52%), Gaps = 4/72 (5%)
Query: 2813 DQSEGSILSDDNLDSPDEIDINVDELDTP----DEADSFEYTGHDPTANKDSGQESESIP 2868
D S+ S DD+ D + D + D+ + P D++++ + + D A+ DS +SE+
Sbjct: 237 DSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASD 296
Query: 2869 EYTAEEEREDNR 2880
+ + + E D++
Sbjct: 297 DSSDDSEAPDDK 308
Score = 32.0 bits (71), Expect = 9.7
Identities = 48/275 (17%), Positives = 101/275 (36%), Gaps = 19/275 (6%)
Query: 981 DEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSRNRISSGPGNLDMWASPHTDN 1040
D + P + E+ D NS ++++ P + S +S ++ ++D+
Sbjct: 141 DNSDDSEAPDDNSDDSEAPDDNS--DDSEAPDDNSDDSEAPDDNSDDSDVP---DDNSDD 195
Query: 1041 SSEINTTHNLDENELKTEHTDGK--NISMEDDVGESSQSSYDDPSMMQLYNETNRQLTLL 1098
SS+ N+ + D+N ++ D K + + DD + S D + ++++
Sbjct: 196 SSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAP 255
Query: 1099 HSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDDCSGGAAIPSDGQTEGYMA 1158
S++ + DS D S A+ D+ DD S + P D + +
Sbjct: 256 DDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVP 315
Query: 1159 EGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSAPSEHHTLNEKSGQLIANS 1218
E ++ + ++ ++ +PA D + S+ L E + + +
Sbjct: 316 EDKSDDS----------DVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHD 365
Query: 1219 IWDSVMRDKDMSSFMLPGSSHITDSE--QRELPPE 1251
D + P S + E +R+LP E
Sbjct: 366 SSDDAGEQDLGENLSKPPSDPEANPEVSERKLPTE 400
>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
Length = 910
Score = 40.0 bits (92), Expect = 0.036
Identities = 63/316 (19%), Positives = 123/316 (38%), Gaps = 30/316 (9%)
Query: 1248 LPPEIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENP 1307
LPPE+ ++ +P +P++S + + ++I + +++T + + + + +NP
Sbjct: 109 LPPELAGVVEEPEEDAAPASPSSSVVNPASSVID-MSQENTRKPNVSPE------KRKNP 161
Query: 1308 GYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENAS----GISEKGQSDQ 1363
F +GH Q+++E+ G T +E+ ++ E ++ I + +S Q
Sbjct: 162 --FNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQ 219
Query: 1364 ELSSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADN 1423
L L S +I K + + ++ + + +L +R G+ N
Sbjct: 220 TLPGL--SNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTD-SLKARGAPRGILKRN 276
Query: 1424 LQPKDTHEKHLMSQRNSGETTE-TSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPP 1482
T + L N ++ S G+ + +S E LE N LEP
Sbjct: 277 SSSSSTDSETLRYNHNFEPKSKIVSPGLTIHERISEKEHSLEDNSSPNSLEPLK------ 330
Query: 1483 HRVPRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYT- 1541
V S ++P + E + L+ +N + AG + F D S+Y
Sbjct: 331 -HVRFSAVKDELPQSPGLIHGREVGEFSV-LESDRLKNGMEDAGDTEEFQSDPKPSQYRK 388
Query: 1542 ----HSSASSPELNDS 1553
H S SSP ++ S
Sbjct: 389 PSLFHQSTSSPYVSKS 404
>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
Length = 934
Score = 40.0 bits (92), Expect = 0.036
Identities = 63/316 (19%), Positives = 123/316 (38%), Gaps = 30/316 (9%)
Query: 1248 LPPEIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENP 1307
LPPE+ ++ +P +P++S + + ++I + +++T + + + + +NP
Sbjct: 109 LPPELAGVVEEPEEDAAPASPSSSVVNPASSVID-MSQENTRKPNVSPE------KRKNP 161
Query: 1308 GYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENAS----GISEKGQSDQ 1363
F +GH Q+++E+ G T +E+ ++ E ++ I + +S Q
Sbjct: 162 --FNSSKLPEGHSSQQTKNEQSKNGRTGLFQTSKEDELSESKEKSTVADTSIQKLEKSKQ 219
Query: 1364 ELSSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADN 1423
L L S +I K + + ++ + + +L +R G+ N
Sbjct: 220 TLPGL--SNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTD-SLKARGAPRGILKRN 276
Query: 1424 LQPKDTHEKHLMSQRNSGETTE-TSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPP 1482
T + L N ++ S G+ + +S E LE N LEP
Sbjct: 277 SSSSSTDSETLRYNHNFEPKSKIVSPGLTIHERISEKEHSLEDNSSPNSLEPLK------ 330
Query: 1483 HRVPRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYT- 1541
V S ++P + E + L+ +N + AG + F D S+Y
Sbjct: 331 -HVRFSAVKDELPQSPGLIHGREVGEFSV-LESDRLKNGMEDAGDTEEFQSDPKPSQYRK 388
Query: 1542 ----HSSASSPELNDS 1553
H S SSP ++ S
Sbjct: 389 PSLFHQSTSSPYVSKS 404
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 40.0 bits (92), Expect = 0.036
Identities = 66/284 (23%), Positives = 116/284 (40%), Gaps = 43/284 (15%)
Query: 1496 IDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGN--FDRDT-ISSEYTHSSASSPELND 1552
I+ V + + TK K + L G S + F +D + ++ H + EL D
Sbjct: 66 IELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCELENQEAHEQDGNDELKD 125
Query: 1553 SSVALSSWGQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRINEFE- 1611
S +G+ + + +E+N + ELI +G ++D+EK I E
Sbjct: 126 SE----EFGENEEENVHSKELLS-AEENKRAHELIEAEG-------IEDIEKEDIESQEI 173
Query: 1612 KSFDRKTPTFLEIWND-----------SVDGDSFSSLSSPETGKYSEHSGT-HQESNLIA 1659
++ + + TFL + S DG S P G +E T H+E
Sbjct: 174 EAQEGEDDTFLTAQDGEEEENEKDIAGSGDGTQEVSKPLPSEGSLAEADHTAHEEMEAHT 233
Query: 1660 SYQEKNEHDISATVQPEDARVIS------TSSGSDDDSVGGEESIEEEIQVANCHVAEDE 1713
+ +E + +IS T+Q EDA + +G + E S ++ Q A E E
Sbjct: 234 TVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQSPEKE 293
Query: 1714 SRAWDSLNESNK-----FLVTADPKSENIYDYLDSSEPAENENK 1752
S+ ++ +N ++K V DP + + +SS+ AE+ +K
Sbjct: 294 SKDYE-MNANHKDGKKEDCVKGDPVEK---EARESSKKAESGDK 333
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 40.0 bits (92), Expect = 0.036
Identities = 87/400 (21%), Positives = 139/400 (34%), Gaps = 64/400 (16%)
Query: 2305 DASGLNTSTGTIDDMSKLTLSEGHPETPVDGDLGKQDICSSEASWGDFEYDVMGQNIDED 2364
+ +G S+ T D K E E P + G++ +C S + E + + +
Sbjct: 929 EGAGFEESSETGDYEEKAETEEA--EEPEED--GEEHVCVSASKHSPTEDEESAKAEADA 984
Query: 2365 LLREPEHFLYGGDPPLEEDSLKQSLAPYTPPFDLSYLTEPAQSAETIEEAGSPEDESLGC 2424
+RE + GD EED + + E A + E+A E E
Sbjct: 985 YIREKRESVASGDDRAEED-----MDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKM 1039
Query: 2425 RAAEIVLSALPDRRSEGNQAETKN---RLPGSQLAVLHIREDPESVY----LPVGAGSNI 2477
A + V+ A+ D+ +E AE + P QL +P S LP G+ S
Sbjct: 1040 EAEDYVM-AVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSESEA 1098
Query: 2478 LSPSNVDWEVETDNSDLPAGGDIGPPNGASKEISELEEEKTIPTKEPEQIKSEYKEERCT 2537
+ E + D P + +G ++ E+ E T P E + +E
Sbjct: 1099 TASD------EENREDQPE--EFTATSGYTQSTIEISSEPT-PMDEMSTPRDVMSDE--- 1146
Query: 2538 EKNEDRHALHMDYILVNREENS-----HSKPETCEERESIAELELYVGSKETGLQGTQLA 2592
NE+ + +++ + + E+S +SKP +E GSK G
Sbjct: 1147 TNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFSE-----GSKTDATDGKDYN 1201
Query: 2593 SFPDTCQPASLNERKGLSAEKMSSKSDTRSSFESPAQDQSWMFLGHSEVGDPSLDARDSG 2652
+ T P S E E S+S R ++ S + +LD +DS
Sbjct: 1202 ASASTISPPSSME------EDKFSRSALRDAYCSEVK------------ASTTLDIKDSI 1243
Query: 2653 PGWSGKTVEPFSELGLGEGPQLQILEEMKPLESLALEEAS 2692
S + V P L P PLE L E S
Sbjct: 1244 SAVSSEKVSPSKSPSLSPSPP-------SPLEKTPLGERS 1276
Score = 38.9 bits (89), Expect = 0.080
Identities = 97/418 (23%), Positives = 151/418 (36%), Gaps = 58/418 (13%)
Query: 2142 DEEPIYEPGREFVPSNAELDSENATVLPPIGYQADIKGSSQPASHKGSPEPSEINGDNST 2201
+E P E VP + +S VL P+ I S S + + + G S
Sbjct: 1372 NERASVSPMDEPVPDS---ESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGAESP 1428
Query: 2202 GLQVSEKGASPDMAPILEPVDRRIPRIENVATSIFVTHQEPTPEGDGSWISDSFSPESQP 2261
+ S K SPD P E +TS++ QE S F+P +
Sbjct: 1429 FEEKSGKQGSPDQVS---------PVSEMTSTSLYQDKQEGK--------STDFAPIKED 1471
Query: 2262 GARALFDGDPHLSTENPALVPDALLASD---TCLDISEAAFDHSFSDASGLNTSTGTIDD 2318
+ D + PAL D D T +D+S+ SF + + ++ S GT+ D
Sbjct: 1472 FGQEKKTDDVEAMSSQPALALDERKLGDVSPTQIDVSQFG---SFKEDTKMSISEGTVSD 1528
Query: 2319 MSKLTLSEGHPETPVDGDLGKQDICSSEASWGDFEYDVMGQNIDEDLLREPEHFLYGGDP 2378
S + EG E G + ++ + F + +D+ P G P
Sbjct: 1529 KSATPVDEGVAEDTYSHMEGVASVSTASVATSSFP-----EPTTDDV--SPSLHAEVGSP 1581
Query: 2379 PLEE--DSLKQSLAPYTPPFDLSYLTEPAQSAETIEEAGSPEDESLGCRAAEIVLSALPD 2436
E DSL S+ F TE + S E S + A+ + + D
Sbjct: 1582 HSTEVDDSLSVSVVQTPTTFQ---ETEMSPSKEECPRPMSISPPDFSPKTAK-SRTPVQD 1637
Query: 2437 RRSEGN--QAETKNRLPGSQLAVLHIREDPESVYLPVGAGSNILS---PSNVDWEVETDN 2491
RSE + E P LA+ R+ P+ + VGAG ++ P+ VD+ +D
Sbjct: 1638 HRSEQSSMSIEFGQESPEQSLAMDFSRQSPD--HPTVGAGVLHITENGPTEVDYS-PSDM 1694
Query: 2492 SDLPAGGDIGP--------PNGASKEISELEEEKTIPTKE---PEQIKSEYKEERCTE 2538
D I P N S+ IS + E + T P QI S +E+ ++
Sbjct: 1695 QDSSLSHKIPPMEEPSYTQDNDLSELISVSQVEASPSTSSAHTPSQIASPLQEDTLSD 1752
Score = 35.4 bits (80), Expect = 0.88
Identities = 49/251 (19%), Positives = 99/251 (39%), Gaps = 26/251 (10%)
Query: 2502 PPNGASKEISELEEEKTIPTKEPEQIKSEYKEERCTEKNEDRHALHMDYILVNREENSHS 2561
P KE E +K + +E +++K E KE + K + A L ++ +
Sbjct: 696 PKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAAL 755
Query: 2562 KPETCEERESIAELELYVGS-KETGLQGTQLASFPDTCQPASLNERKGLSAEKMSSKSDT 2620
KP+ ++ ES+ + + G KE G + +++G +AE +++ T
Sbjct: 756 KPKVPKKEESVKKDSVAAGKPKEKG--------------KIKVIKKEGKAAEAVAAAVGT 801
Query: 2621 RSSFESPAQDQSWMFLGHSEVGDPSLDARDSGPGWSGKTVEPFSELGLGE-------GPQ 2673
++ + +G ++ L+A S + F EL E PQ
Sbjct: 802 GATTAAVMAAAGIAAIGPAK----ELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQ 857
Query: 2674 LQILEEMKPLESLALEEASGPVSQSQKSKSRGRAGPDAVTLQAVTHDNEWEMLSPQPVQK 2733
L+++E+ + L+ EA + + +K + + +T + E +PV+K
Sbjct: 858 LELIEDEEKLKETEPVEAYVIQKEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEK 917
Query: 2734 NMIPDTEMEEE 2744
+ D E E+
Sbjct: 918 QGVDDIEKFED 928
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.127 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 135,546,234
Number of Sequences: 37866
Number of extensions: 7141526
Number of successful extensions: 21105
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 267
Number of HSP's that attempted gapping in prelim test: 19604
Number of HSP's gapped (non-prelim): 1650
length of query: 3088
length of database: 18,247,518
effective HSP length: 121
effective length of query: 2967
effective length of database: 13,665,732
effective search space: 40546226844
effective search space used: 40546226844
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.