Guide to the Human Genome
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Search of human proteins with 159032020

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|159032020 gap junction protein, beta 6 [Homo sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|159032020 gap junction protein, beta 6 [Homo sapiens]              547   e-156
gi|158966714 gap junction protein, beta 6 [Homo sapiens]              547   e-156
gi|158966717 gap junction protein, beta 6 [Homo sapiens]              547   e-156
gi|40254837 gap junction protein, beta 6 [Homo sapiens]               547   e-156
gi|42558283 gap junction protein beta 2 [Homo sapiens]                381   e-106
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]       322   2e-88
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]         322   2e-88
gi|23397464 gap junction protein, beta 4 [Homo sapiens]               257   8e-69
gi|54607056 connexin 31 [Homo sapiens]                                255   3e-68
gi|13128960 connexin 31 [Homo sapiens]                                255   3e-68
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]      253   2e-67
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]        233   1e-61
gi|55953076 connexin 50 [Homo sapiens]                                229   1e-60
gi|62865885 connexin 37 [Homo sapiens]                                215   3e-56
gi|22779877 connexin 46 [Homo sapiens]                                214   5e-56
gi|4504001 connexin 43 [Homo sapiens]                                 206   1e-53
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]       205   3e-53
gi|32483412 connexin 40 [Homo sapiens]                                198   5e-51
gi|6631083 connexin 40 [Homo sapiens]                                 198   5e-51
gi|14211941 gap junction protein, alpha 10 [Homo sapiens]             196   2e-50
gi|122939172 connexin 45 [Homo sapiens]                               160   1e-39
gi|69122473 connexin 45 [Homo sapiens]                                160   1e-39
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]       153   2e-37
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]    147   9e-36
gi|145699105 connexin40.1 [Homo sapiens]                              135   5e-32
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]     127   1e-29
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]       112   3e-25
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]           83   2e-16
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]           83   2e-16
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]           83   2e-16

>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  547 bits (1409), Expect = e-156
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
           KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
           IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK 240
           FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK 240

Query: 241 QNEMNELISDSGQNAITGFPS 261
           QNEMNELISDSGQNAITGFPS
Sbjct: 241 QNEMNELISDSGQNAITGFPS 261


>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  547 bits (1409), Expect = e-156
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
           KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
           IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK 240
           FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK 240

Query: 241 QNEMNELISDSGQNAITGFPS 261
           QNEMNELISDSGQNAITGFPS
Sbjct: 241 QNEMNELISDSGQNAITGFPS 261


>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  547 bits (1409), Expect = e-156
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
           KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
           IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK 240
           FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK 240

Query: 241 QNEMNELISDSGQNAITGFPS 261
           QNEMNELISDSGQNAITGFPS
Sbjct: 241 QNEMNELISDSGQNAITGFPS 261


>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  547 bits (1409), Expect = e-156
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC
Sbjct: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
           KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED
Sbjct: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
           IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK 240
           FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKESK 240

Query: 241 QNEMNELISDSGQNAITGFPS 261
           QNEMNELISDSGQNAITGFPS
Sbjct: 241 QNEMNELISDSGQNAITGFPS 261


>gi|42558283 gap junction protein beta 2 [Homo sapiens]
          Length = 226

 Score =  381 bits (979), Expect = e-106
 Identities = 173/224 (77%), Positives = 201/224 (89%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           MDWGTL T +GGVNKHSTSIGK+W+TV+FIFR+MILVVAA+EVWGDEQ DFVCNTLQPGC
Sbjct: 1   MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
           KNVCYDH+FP+SHIRLWALQLIFVSTPALLVAMHVAY RHE  RKF +GE +++FKDIE+
Sbjct: 61  KNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEE 120

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
           IK QKVRIEGSLWWTYTSSIFFR+IFEAAFMYVFY +Y+G+ +  ++KC   PCPN VDC
Sbjct: 121 IKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDC 180

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKR 224
           F+SRPTEKTVFT+FMI+ S IC+LLNV ELCYLL++ C  +SK+
Sbjct: 181 FVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKK 224


>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  322 bits (826), Expect = 2e-88
 Identities = 148/255 (58%), Positives = 197/255 (77%), Gaps = 6/255 (2%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           M+W  L+T + GVN+HST+IG+VW++VIFIFR+M+LVVAA+ VWGDE+  F+CNTLQPGC
Sbjct: 1   MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
            +VCYD FFP+SH+RLW+LQLI VSTPALLVAMHVA+ +H   +K  R E   D   +E+
Sbjct: 61  NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQH-IEKKMLRLEGHGDPLHLEE 119

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
           +K+ KV I G+LWWTY  S+ FR++FEA FMYVFY LY GY +  ++KC + PCPN VDC
Sbjct: 120 VKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDC 179

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHP----NHAL 236
           F+SRPTEKTVFT+FM++AS IC++LNVAE+ YL+++ C RR++R     +       H L
Sbjct: 180 FVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRL 239

Query: 237 K-ESKQNEMNELISD 250
             E KQNE+N+L+S+
Sbjct: 240 SPEYKQNEINKLLSE 254


>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  322 bits (826), Expect = 2e-88
 Identities = 148/255 (58%), Positives = 197/255 (77%), Gaps = 6/255 (2%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           M+W  L+T + GVN+HST+IG+VW++VIFIFR+M+LVVAA+ VWGDE+  F+CNTLQPGC
Sbjct: 1   MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
            +VCYD FFP+SH+RLW+LQLI VSTPALLVAMHVA+ +H   +K  R E   D   +E+
Sbjct: 61  NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQH-IEKKMLRLEGHGDPLHLEE 119

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
           +K+ KV I G+LWWTY  S+ FR++FEA FMYVFY LY GY +  ++KC + PCPN VDC
Sbjct: 120 VKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDC 179

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHP----NHAL 236
           F+SRPTEKTVFT+FM++AS IC++LNVAE+ YL+++ C RR++R     +       H L
Sbjct: 180 FVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRL 239

Query: 237 K-ESKQNEMNELISD 250
             E KQNE+N+L+S+
Sbjct: 240 SPEYKQNEINKLLSE 254


>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
          Length = 266

 Score =  257 bits (656), Expect = 8e-69
 Identities = 117/218 (53%), Positives = 158/218 (72%), Gaps = 5/218 (2%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           M+W  L   + GVNK+ST + ++W++V+FIFRV++ VVAA+EVW DEQ+DFVCNT QPGC
Sbjct: 1   MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
            NVCYD FFPVSH+RLWALQLI V+ P+LLV MHVA YR E  RK       N     ++
Sbjct: 61  PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREERERKHHLKHGPNAPSLYDN 119

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
           + K++    G LWWTY  S+ F+   +A F+Y+F+ LY  Y +P V+ C ++PCP+ VDC
Sbjct: 120 LSKKR----GGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDC 175

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVC 218
           +ISRPTEK VFT FM++ + IC+LLN++E+ YL+ K C
Sbjct: 176 YISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRC 213


>gi|54607056 connexin 31 [Homo sapiens]
          Length = 270

 Score =  255 bits (651), Expect = 3e-68
 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           MDW TL   + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC
Sbjct: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
            NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E  R+ R+       K  ++
Sbjct: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179
             K+     G LWWTY  S+ F++I E  F+Y+ + L++G+++P +++C  + PCPN+VD
Sbjct: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175

Query: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214
           C+I+RPTEK +FT FM+ AS +C++L + ELCYL+
Sbjct: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210


>gi|13128960 connexin 31 [Homo sapiens]
          Length = 270

 Score =  255 bits (651), Expect = 3e-68
 Identities = 112/215 (52%), Positives = 162/215 (75%), Gaps = 6/215 (2%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           MDW TL   + GVNK+ST+ G++W++V+F+FRV++ VVAA+ VWGDEQ+DF CNT QPGC
Sbjct: 1   MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
            NVCYD++FP+S+IRLWALQLIFV+ P+LLV +HVA YR E  R+ R+       K  ++
Sbjct: 61  TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVA-YREERERRHRQKHGDQCAKLYDN 119

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKC-GIDPCPNLVD 179
             K+     G LWWTY  S+ F++I E  F+Y+ + L++G+++P +++C  + PCPN+VD
Sbjct: 120 AGKK----HGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVD 175

Query: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLL 214
           C+I+RPTEK +FT FM+ AS +C++L + ELCYL+
Sbjct: 176 CYIARPTEKKIFTYFMVGASAVCIVLTICELCYLI 210


>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
          Length = 273

 Score =  253 bits (645), Expect = 2e-67
 Identities = 116/248 (46%), Positives = 165/248 (66%), Gaps = 9/248 (3%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           M+W      + GVNK+ST+ G++W++++FIFRV++ +V A+ VW D+ +DF CNT QPGC
Sbjct: 1   MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
            NVC+D FFPVSH+RLWALQLI V+ P+LLV MHVA YR    ++ R     N  +   +
Sbjct: 61  SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVA-YREVQEKRHREAHGENSGRLYLN 119

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
             K++    G LWWTY  S+ F+   + AF+YVF+  Y  Y LP V+KC  DPCPN+VDC
Sbjct: 120 PGKKR----GGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDC 175

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR----RSKRAQTQKNHPNHAL 236
           FIS+P+EK +FT+FM++ + IC+LLN+ EL YL+ K C      R  +A    +HP+   
Sbjct: 176 FISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQAMCTGHHPHGTT 235

Query: 237 KESKQNEM 244
              KQ+++
Sbjct: 236 SSCKQDDL 243


>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
          Length = 223

 Score =  233 bits (594), Expect = 1e-61
 Identities = 106/219 (48%), Positives = 151/219 (68%), Gaps = 13/219 (5%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           M W  L   + GVNK+ST  G +W+ V+F+FR+++ +VAA+ VW DEQ++F CN+ QPGC
Sbjct: 1   MSWMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
           KNVC+D FFP+S +RLWALQLI VSTP+LLV +HVAY  HE   K  R          + 
Sbjct: 61  KNVCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAY--HEGREKRHR----------KK 108

Query: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
           +      ++G LW+ Y  S+  +  FE  F+ +FY LY+G+ +P+++KC + PCPN VDC
Sbjct: 109 LYVSPGTMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKCDLKPCPNTVDC 168

Query: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCF 219
           FIS+PTEKT+F +F++  S +C++LN  EL +L+LK CF
Sbjct: 169 FISKPTEKTIFILFLVITSCLCIVLNFIELSFLVLK-CF 206


>gi|55953076 connexin 50 [Homo sapiens]
          Length = 433

 Score =  229 bits (585), Expect = 1e-60
 Identities = 117/229 (51%), Positives = 152/229 (66%), Gaps = 15/229 (6%)

Query: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
           DW  L   +  VN+HST IG+VW+TV+FIFR++IL  AA+ VWGDEQ DFVCNT QPGC+
Sbjct: 3   DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62

Query: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEK------RND 114
           NVCYD  FP+SHIRLW LQ+IFVSTP+L+   H  +Y R E  RK R  E+       N 
Sbjct: 63  NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122

Query: 115 FKDIEDIKK-------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVL 167
             D   +KK       +K R+EG+L  TY   I F+ +FE  F+   YFLY G+ +  + 
Sbjct: 123 GPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPLY 181

Query: 168 KCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLK 216
           +C   PCPN+VDCF+SRPTEKT+F +FM+S + + + LNV EL +L LK
Sbjct: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLK 230


>gi|62865885 connexin 37 [Homo sapiens]
          Length = 333

 Score =  215 bits (548), Expect = 3e-56
 Identities = 111/249 (44%), Positives = 150/249 (60%), Gaps = 20/249 (8%)

Query: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
           DWG L   +  V +HST +GK+W+TV+FIFR++IL +A + VWGDEQ DF CNT QPGC 
Sbjct: 3   DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62

Query: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYY-RHETTRKFRRGEKR-------- 112
           NVCYD  FP+SHIR W LQ +FVSTP L+   HV Y  R E   + + GE R        
Sbjct: 63  NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122

Query: 113 ---------NDFKDIEDIKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHL 163
                         I   +  ++RI G+L  TY +S+  + + EA F+Y  + LY G+ +
Sbjct: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181

Query: 164 PWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSK 223
             V  C   PCP LVDCF+SRPTEKT+F IFM+   +I ++LN+ EL +LL + C  R  
Sbjct: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCR-CLSRGM 240

Query: 224 RAQTQKNHP 232
           RA+  ++ P
Sbjct: 241 RARQGQDAP 249


>gi|22779877 connexin 46 [Homo sapiens]
          Length = 435

 Score =  214 bits (546), Expect = 5e-56
 Identities = 107/231 (46%), Positives = 146/231 (63%), Gaps = 27/231 (11%)

Query: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
           DW  L   +    +HST IGKVW+TV+FIFR+++L  AA++VWGDEQ DF CNT QPGC+
Sbjct: 3   DWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPGCE 62

Query: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIEDI 121
           NVCYD  FP+SHIR WALQ+IFVSTP L+   HV +         R  EK+ + ++ E +
Sbjct: 63  NVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHI-------VRMEEKKKEREEEEQL 115

Query: 122 KKQ-------------------KVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYH 162
           K++                   +VR+ G+L  TY  +I F+ +FE  F+   YFLY G+ 
Sbjct: 116 KRESPSPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLY-GFE 174

Query: 163 LPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
           L  + +C   PCPN VDCFISRPTEKT+F IFM++ +   +LLN+ E+ +L
Sbjct: 175 LKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHL 225


>gi|4504001 connexin 43 [Homo sapiens]
          Length = 382

 Score =  206 bits (525), Expect = 1e-53
 Identities = 109/252 (43%), Positives = 152/252 (60%), Gaps = 23/252 (9%)

Query: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
           DW  L   +  V  +ST+ GKVW++V+FIFR+++L  A +  WGDEQ  F CNT QPGC+
Sbjct: 3   DWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCE 62

Query: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEK----RNDFKD 117
           NVCYD  FP+SH+R W LQ+IFVS P LL   HV Y   +  +  ++ E+    + D  +
Sbjct: 63  NVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVN 122

Query: 118 IE------DIKK--------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHL 163
           ++      +IKK         KV++ G L  TY  SI F+ IFE AF+ + +++Y G+ L
Sbjct: 123 VDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIY-GFSL 181

Query: 164 PWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSK 223
             V  C  DPCP+ VDCF+SRPTEKT+F IFM+  S++ + LN+ EL Y    V F+  K
Sbjct: 182 SAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFY----VFFKGVK 237

Query: 224 RAQTQKNHPNHA 235
                K+ P HA
Sbjct: 238 DRVKGKSDPYHA 249


>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
          Length = 515

 Score =  205 bits (522), Expect = 3e-53
 Identities = 109/266 (40%), Positives = 159/266 (59%), Gaps = 30/266 (11%)

Query: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
           DW  L   +  V+ HST IGK+W+T++FIFR+++L VAA++VW DEQ  F+CNT QPGC+
Sbjct: 3   DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62

Query: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRH--ETTRKFRRGEKRNDFKDIE 119
           NVCYD  FP+S IR W LQ+IFVS+P+L+   H  Y     E  R+  + + R + +++E
Sbjct: 63  NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122

Query: 120 ---------------DIKKQKVR---IEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
                           ++K+K+    + G+L  TY   IF R + E  FM   Y LY G+
Sbjct: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181

Query: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
           HL  + KC   PCPN++DCF+SRPTEKT+F +FM S + I + LN+ E+ +L     F++
Sbjct: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHL----GFKK 237

Query: 222 SKRA-----QTQKNHPNHALKESKQN 242
            KR      + +K H      ++KQN
Sbjct: 238 IKRGLWGKYKLKKEHNEFHANKAKQN 263


>gi|32483412 connexin 40 [Homo sapiens]
          Length = 358

 Score =  198 bits (503), Expect = 5e-51
 Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)

Query: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
           DW  L  F+  V+KHST +GKVW+TV+FIFR+++L  AA+  WGDEQ DF C+T+QPGC+
Sbjct: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62

Query: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120
           NVCYD  FP+SHIR W LQ+IFVSTP+L+   H  +  R +  RK R  E+  + +    
Sbjct: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122

Query: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165
            +                 ++ ++G+L  TY  SI  R   E  F+   YF+Y G  L  
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181

Query: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
           +  C   PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229


>gi|6631083 connexin 40 [Homo sapiens]
          Length = 358

 Score =  198 bits (503), Expect = 5e-51
 Identities = 98/228 (42%), Positives = 141/228 (61%), Gaps = 17/228 (7%)

Query: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
           DW  L  F+  V+KHST +GKVW+TV+FIFR+++L  AA+  WGDEQ DF C+T+QPGC+
Sbjct: 3   DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62

Query: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY-YRHETTRKFRRGEKRNDFKDIED 120
           NVCYD  FP+SHIR W LQ+IFVSTP+L+   H  +  R +  RK R  E+  + +    
Sbjct: 63  NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122

Query: 121 IK---------------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPW 165
            +                 ++ ++G+L  TY  SI  R   E  F+   YF+Y G  L  
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181

Query: 166 VLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
           +  C   PCP+ V+C++SRPTEK VF +FM++ + + +LL++AEL +L
Sbjct: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229


>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
          Length = 543

 Score =  196 bits (498), Expect = 2e-50
 Identities = 101/239 (42%), Positives = 142/239 (59%), Gaps = 21/239 (8%)

Query: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
           DW  L   +  V+ HST +GK+W+T++FIFR+++L VAA++VW DEQ  F CNT QPGC 
Sbjct: 3   DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62

Query: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY----YRHETTRK--FRRGEKRNDF 115
           N+CYD  FP+S IR W LQ+IFVS+P+L+   H  Y    +  +  RK    R +  N  
Sbjct: 63  NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122

Query: 116 KDIEDIKK--------------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
            D+E+ ++               KV ++G L  TY   I  R + E  FM   Y LY G+
Sbjct: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181

Query: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR 220
            +  + KC   PCPN VDCF+SRPTEKT+F +FM S + I +LLN+ E+ +L ++   R
Sbjct: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240


>gi|122939172 connexin 45 [Homo sapiens]
          Length = 396

 Score =  160 bits (405), Expect = 1e-39
 Identities = 89/254 (35%), Positives = 135/254 (53%), Gaps = 42/254 (16%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           M W  L   +  ++ HST +GK+W+TV+ +FR+++  V  + ++ DEQ  FVCNT QPGC
Sbjct: 1   MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALL---VAMH-VAYYRH-ETTRKFRRG------ 109
           +NVCYD F P+SH+R W  Q+I V+TP+++    A+H +A   H E  +K  R       
Sbjct: 61  ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120

Query: 110 ----------EKRND-------FKDIEDIKKQKVRI-------------EGSLWWTYTSS 139
                     E+ N+         ++E  K+ K +              E  L   Y   
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180

Query: 140 IFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISAS 199
           +  R +FE  F+   YFLY G+ +     C   PCP+ +DCFISRPTEKT+F + M   +
Sbjct: 181 LLARTVFEVGFLIGQYFLY-GFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVT 239

Query: 200 VICMLLNVAELCYL 213
            +C+LLN+ E+ +L
Sbjct: 240 GLCLLLNIWEMLHL 253


>gi|69122473 connexin 45 [Homo sapiens]
          Length = 396

 Score =  160 bits (405), Expect = 1e-39
 Identities = 89/254 (35%), Positives = 135/254 (53%), Gaps = 42/254 (16%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           M W  L   +  ++ HST +GK+W+TV+ +FR+++  V  + ++ DEQ  FVCNT QPGC
Sbjct: 1   MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALL---VAMH-VAYYRH-ETTRKFRRG------ 109
           +NVCYD F P+SH+R W  Q+I V+TP+++    A+H +A   H E  +K  R       
Sbjct: 61  ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120

Query: 110 ----------EKRND-------FKDIEDIKKQKVRI-------------EGSLWWTYTSS 139
                     E+ N+         ++E  K+ K +              E  L   Y   
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQ 180

Query: 140 IFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISAS 199
           +  R +FE  F+   YFLY G+ +     C   PCP+ +DCFISRPTEKT+F + M   +
Sbjct: 181 LLARTVFEVGFLIGQYFLY-GFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVT 239

Query: 200 VICMLLNVAELCYL 213
            +C+LLN+ E+ +L
Sbjct: 240 GLCLLLNIWEMLHL 253


>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
          Length = 321

 Score =  153 bits (386), Expect = 2e-37
 Identities = 93/277 (33%), Positives = 134/277 (48%), Gaps = 69/277 (24%)

Query: 2   DWGTLHTFI-GGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           +W  L   +   V +HST IG++ +TV+ IFR++I+ +  + V+ DEQ  FVCNTLQPGC
Sbjct: 3   EWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGC 62

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRR------------ 108
              CYD  FP+SHIR W  Q+I V TP+L     + Y  H++ ++  R            
Sbjct: 63  NQACYDRAFPISHIRYWVFQIIMVCTPSL---CFITYSVHQSAKQRERRYSTVFLALDRD 119

Query: 109 -----------------GEKRNDFK----------------------DIEDIK------- 122
                            G KR D K                      D  ++K       
Sbjct: 120 PPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPS 179

Query: 123 ------KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPN 176
                 K K+R +  +   Y   + FR   E  F+   YFLY G+ +P + +C   PC  
Sbjct: 180 GLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIK 238

Query: 177 LVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYL 213
            V+C++SRPTEKTVF +FM + S IC++LN+AEL +L
Sbjct: 239 EVECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHL 275


>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
          Length = 294

 Score =  147 bits (371), Expect = 9e-36
 Identities = 83/242 (34%), Positives = 128/242 (52%), Gaps = 10/242 (4%)

Query: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
           +W  L + +  V   S  +G++W+ V+ IFR+++L      V+ DEQE+FVCNTLQPGC+
Sbjct: 3   EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62

Query: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRND-FKDIED 120
             CYD  FPVSH R W   ++ +S P +L    V Y  H   ++    E        + +
Sbjct: 63  QTCYDRAFPVSHYRFWLFHILLLSAPPVL---FVVYSMHRAGKEAGGAEAAAQCAPGLPE 119

Query: 121 IKKQKVRIEG-SLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVD 179
            +     +        Y  S+  R++ E  F+     LY G+ +     C   PCP+ VD
Sbjct: 120 AQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVD 178

Query: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKES 239
           CF+SRPTEKTVF +F  +  ++  LL+VAEL +LL    ++   RA  + N  N A +E+
Sbjct: 179 CFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLL----WKGRPRAGERDNRCNRAHEEA 234

Query: 240 KQ 241
           ++
Sbjct: 235 QK 236


>gi|145699105 connexin40.1 [Homo sapiens]
          Length = 370

 Score =  135 bits (339), Expect = 5e-32
 Identities = 77/218 (35%), Positives = 121/218 (55%), Gaps = 13/218 (5%)

Query: 13  VNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVS 72
           +N + T +GK+W  +  + R++++V+A + V+ DEQE FVCNTLQPGC NVCYD F PVS
Sbjct: 14  LNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVS 73

Query: 73  HIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKR-NDFKDIEDIKKQKVRIEGS 131
           H+R W +Q + V  P+ + +++V    H        G +R  D ++    +++  R  G 
Sbjct: 74  HLRFWLIQGVCVLLPSAVFSVYVL---HRGATLAALGPRRCPDPREPASGQRRCPRPFGE 130

Query: 132 LWWT--------YTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFIS 183
                       Y   +  R + EAAF  + YFL+ G+  P    C   PC  +VDC++S
Sbjct: 131 RGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCYVS 189

Query: 184 RPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
           RPTEK++  +F+ + S +  LL +A+L   L +   RR
Sbjct: 190 RPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRR 227


>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
          Length = 279

 Score =  127 bits (318), Expect = 1e-29
 Identities = 68/230 (29%), Positives = 119/230 (51%), Gaps = 8/230 (3%)

Query: 6   LHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCY 65
           L   +   ++ ST +G++ + V+  FR+++L  +   V+GDEQ +FVC+T QPGCK  C+
Sbjct: 6   LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65

Query: 66  DHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIEDIKKQK 125
           D F P+S +R W  Q+I V+ P+   A+++ +  +     +    K  + + +   ++  
Sbjct: 66  DAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQGREGN 122

Query: 126 VRIEGS----LWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCF 181
             + G+    L W Y + +  R++ E A + + Y LY G+ +P    C  +PC   + C 
Sbjct: 123 TDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181

Query: 182 ISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNH 231
           +SRP+EKT+F   M   S  C+L    EL  L L   +R  K   +   +
Sbjct: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKY 231


>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
          Length = 439

 Score =  112 bits (280), Expect = 3e-25
 Identities = 46/112 (41%), Positives = 70/112 (62%), Gaps = 3/112 (2%)

Query: 1   MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
           M W  L   +  ++ HST +GKVW+TV+ +FR+++  V  + ++ DEQ  F CNT QPGC
Sbjct: 4   MSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGC 63

Query: 61  KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKR 112
            NVCYD F P+SH+R W  Q++ +STP++   M++ Y  H   R   +  +R
Sbjct: 64  DNVCYDAFAPLSHVRFWVFQIVVISTPSV---MYLGYAVHRLARASEQERRR 112



 Score = 77.8 bits (190), Expect = 9e-15
 Identities = 38/91 (41%), Positives = 57/91 (62%), Gaps = 2/91 (2%)

Query: 123 KQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFI 182
           +++++ EG L   Y + +  R  FE AF+   Y LY G+ +     C   PCP++VDCF+
Sbjct: 201 RRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLY-GFEVRPFFPCSRQPCPHVVDCFV 258

Query: 183 SRPTEKTVFTIFMISASVICMLLNVAELCYL 213
           SRPTEKTVF + M   S +C+LLN+ E+ +L
Sbjct: 259 SRPTEKTVFLLVMYVVSCLCLLLNLCEMAHL 289


>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 34/75 (45%), Positives = 52/75 (69%)

Query: 16  HSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVSHIR 75
           HST +G++   V+  FR+++L  +   V+GDEQ +FVC+T QPGCK  C+D F P+S +R
Sbjct: 35  HSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLR 94

Query: 76  LWALQLIFVSTPALL 90
            W  Q+I V+ P++L
Sbjct: 95  FWVFQVILVAVPSVL 109


>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 34/75 (45%), Positives = 52/75 (69%)

Query: 16  HSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVSHIR 75
           HST +G++   V+  FR+++L  +   V+GDEQ +FVC+T QPGCK  C+D F P+S +R
Sbjct: 35  HSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLR 94

Query: 76  LWALQLIFVSTPALL 90
            W  Q+I V+ P++L
Sbjct: 95  FWVFQVILVAVPSVL 109


>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 34/75 (45%), Positives = 52/75 (69%)

Query: 16  HSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVSHIR 75
           HST +G++   V+  FR+++L  +   V+GDEQ +FVC+T QPGCK  C+D F P+S +R
Sbjct: 35  HSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLR 94

Query: 76  LWALQLIFVSTPALL 90
            W  Q+I V+ P++L
Sbjct: 95  FWVFQVILVAVPSVL 109


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.456 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,610,887
Number of Sequences: 37866
Number of extensions: 380165
Number of successful extensions: 1218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1137
Number of HSP's gapped (non-prelim): 58
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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