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Search of human proteins with 157785548
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157785548 PAS domain containing 1 [Homo sapiens]
(773 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157785548 PAS domain containing 1 [Homo sapiens] 1556 0.0
gi|4758010 clock [Homo sapiens] 102 2e-21
gi|22027471 neuronal PAS domain protein 2 [Homo sapiens] 101 3e-21
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 76 1e-13
gi|221139761 zinc finger protein 853 [Homo sapiens] 75 3e-13
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 73 1e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 72 1e-12
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 72 2e-12
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 69 1e-11
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 69 1e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 69 1e-11
gi|148746195 trichohyalin [Homo sapiens] 68 4e-11
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 67 6e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 67 6e-11
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 66 1e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 66 1e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 65 2e-10
gi|93141033 PAX interacting protein 1 [Homo sapiens] 64 5e-10
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 63 9e-10
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 63 9e-10
gi|110347429 mediator complex subunit 12 [Homo sapiens] 62 2e-09
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 61 3e-09
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 61 3e-09
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 61 5e-09
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 61 5e-09
gi|33286444 mastermind-like 2 [Homo sapiens] 59 1e-08
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 59 1e-08
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 59 1e-08
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 59 2e-08
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 59 2e-08
>gi|157785548 PAS domain containing 1 [Homo sapiens]
Length = 773
Score = 1556 bits (4028), Expect = 0.0
Identities = 773/773 (100%), Positives = 773/773 (100%)
Query: 1 MKMRGEKRRDKVNPKSSQRKLNWIPSFPTYDYFNQVTLQLLDGFMITLSTDGVIICVAEN 60
MKMRGEKRRDKVNPKSSQRKLNWIPSFPTYDYFNQVTLQLLDGFMITLSTDGVIICVAEN
Sbjct: 1 MKMRGEKRRDKVNPKSSQRKLNWIPSFPTYDYFNQVTLQLLDGFMITLSTDGVIICVAEN 60
Query: 61 ISSLLGHLPAEIVGKKLLSLLPDEEKDEVYQKIILKFPLLNSETHIEFCCHLKRGNVEHG 120
ISSLLGHLPAEIVGKKLLSLLPDEEKDEVYQKIILKFPLLNSETHIEFCCHLKRGNVEHG
Sbjct: 61 ISSLLGHLPAEIVGKKLLSLLPDEEKDEVYQKIILKFPLLNSETHIEFCCHLKRGNVEHG 120
Query: 121 DSSAYENVKFIVNVRDICNEFPVVFSGLFSSHLCADFAACVPQEDRLYLVGNVCILRTQL 180
DSSAYENVKFIVNVRDICNEFPVVFSGLFSSHLCADFAACVPQEDRLYLVGNVCILRTQL
Sbjct: 121 DSSAYENVKFIVNVRDICNEFPVVFSGLFSSHLCADFAACVPQEDRLYLVGNVCILRTQL 180
Query: 181 LQQLYTSKAVSDEAVLTQDSDEEPFVGELSSSQGQRGHTSMKAVYVEPAAAAAAAAISDD 240
LQQLYTSKAVSDEAVLTQDSDEEPFVGELSSSQGQRGHTSMKAVYVEPAAAAAAAAISDD
Sbjct: 181 LQQLYTSKAVSDEAVLTQDSDEEPFVGELSSSQGQRGHTSMKAVYVEPAAAAAAAAISDD 240
Query: 241 QIDIAEVEQYGPQENVHMFVDSDSTYCSSTVFLDTMPESPALSLQDFRGEPEVNPLYRAD 300
QIDIAEVEQYGPQENVHMFVDSDSTYCSSTVFLDTMPESPALSLQDFRGEPEVNPLYRAD
Sbjct: 241 QIDIAEVEQYGPQENVHMFVDSDSTYCSSTVFLDTMPESPALSLQDFRGEPEVNPLYRAD 300
Query: 301 PVDLEFSVDQVDSVDQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQ 360
PVDLEFSVDQVDSVDQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQ
Sbjct: 301 PVDLEFSVDQVDSVDQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQ 360
Query: 361 PSSPVAYDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVV 420
PSSPVAYDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVV
Sbjct: 361 PSSPVAYDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVV 420
Query: 421 IPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQ 480
IPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQ
Sbjct: 421 IPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQ 480
Query: 481 QLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKK 540
QLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKK
Sbjct: 481 QLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKK 540
Query: 541 KKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNH 600
KKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNH
Sbjct: 541 KKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNH 600
Query: 601 PVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPVNQLPLIDTSN 660
PVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPVNQLPLIDTSN
Sbjct: 601 PVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPVNQLPLIDTSN 660
Query: 661 SEAISSSSIPQFPITSDSTISTLETPQDYIRLWQELSDSLGPVVQVNTWSCDEQGTLHGQ 720
SEAISSSSIPQFPITSDSTISTLETPQDYIRLWQELSDSLGPVVQVNTWSCDEQGTLHGQ
Sbjct: 661 SEAISSSSIPQFPITSDSTISTLETPQDYIRLWQELSDSLGPVVQVNTWSCDEQGTLHGQ 720
Query: 721 PTYHQVQVSEVGVEGPPDPQAFQGPAAYQPDQMRSAEQTRLMPAEQRDSNKPC 773
PTYHQVQVSEVGVEGPPDPQAFQGPAAYQPDQMRSAEQTRLMPAEQRDSNKPC
Sbjct: 721 PTYHQVQVSEVGVEGPPDPQAFQGPAAYQPDQMRSAEQTRLMPAEQRDSNKPC 773
>gi|4758010 clock [Homo sapiens]
Length = 846
Score = 102 bits (253), Expect = 2e-21
Identities = 59/188 (31%), Positives = 104/188 (55%), Gaps = 15/188 (7%)
Query: 16 SSQRKLNWIPSFPTYDYFNQVTLQLLDGFMITLSTDGVIICVAENISSLLGHLPAEIVGK 75
+S+ + +W P+F + + F Q+ L+ LDGF + + TDG II V+E+++SLL HLP+++V +
Sbjct: 93 ASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQ 152
Query: 76 KLLSLLPDEEKDEVYQKIILKFPLLNSET----------HIEFCCHLKRGNVEHGDSSAY 125
+ + +P+ E EVY+ IL LL S++ +EFCCH+ RG ++ + S Y
Sbjct: 153 SIFNFIPEGEHSEVYK--ILSTHLLESDSLTPEYLKSKNQLEFCCHMLRGTIDPKEPSTY 210
Query: 126 ENVKFIVNVRDICNEFPVVFSGLFSSHLCADFAACVPQEDRLYLVGNVCILRTQLLQQLY 185
E VKFI N + + + +G + EDR+ V V + Q ++++
Sbjct: 211 EYVKFIGNFKSLNSVSSSAHNGFEGT---IQRTHRPSYEDRVCFVATVRLATPQFIKEMC 267
Query: 186 TSKAVSDE 193
T + ++E
Sbjct: 268 TVEEPNEE 275
Score = 32.3 bits (72), Expect = 1.7
Identities = 16/40 (40%), Positives = 24/40 (60%)
Query: 371 SQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQ 410
S +L M+ LK+QLE+RT ++ I QQ L + + LQ
Sbjct: 517 SAQLGAMQHLKDQLEQRTRMIEANIHRQQEELRKIQEQLQ 556
>gi|22027471 neuronal PAS domain protein 2 [Homo sapiens]
Length = 824
Score = 101 bits (251), Expect = 3e-21
Identities = 73/228 (32%), Positives = 116/228 (50%), Gaps = 39/228 (17%)
Query: 11 KVNPKSSQRKL-----NWIPSFPTYDYFNQVTLQLLDGFMITLSTDGVIICVAENISSLL 65
K N S+Q ++ +W PSF + + F Q+ L+ LDGF+I ++TDG II V+++I+ LL
Sbjct: 58 KHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTTDGSIIYVSDSITPLL 117
Query: 66 GHLPAEIVGKKLLSLLPDEEKDEVYQKIILKFPL---------LNSETHIEFCCHLKRGN 116
GHLP++++ + LL+ LP++E EVY KI+ L L S++ +EF CHL RG+
Sbjct: 118 GHLPSDVMDQNLLNFLPEQEHSEVY-KILSSHMLVTDSPSPEYLKSDSDLEFYCHLLRGS 176
Query: 117 VEHGDSSAYENVKFIVNVRDICNEFPVVFSGLFSSHLCADFAACVPQEDRLYLVGNVCIL 176
+ + YE +KF+ N R N S C F + + R+ L VC +
Sbjct: 177 LNPKEFPTYEYIKFVGNFRSYNN---------VPSPSCNGFDNTLSRPCRVPLGKEVCFI 227
Query: 177 RT------QLLQQL---------YTSKAVSDEAVLTQDSDEEPFVGEL 209
T Q L+++ +TS+ + L D P +G L
Sbjct: 228 ATVRLATPQFLKEMCIVDEPLEEFTSRHSLEWKFLFLDHRAPPIIGYL 275
Score = 35.4 bits (80), Expect = 0.20
Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%)
Query: 326 ENPVAPLDQAGLMD-PVDPEDSVDLGAAGASAQPLQPSSPVAYDIISQELELMKKLKEQL 384
E PV L QA M P+ S DL LQ S+P S + + + +K+QL
Sbjct: 451 ELPVPGLSQAATMPAPLPSPSSCDLTQQLLPQTVLQ-STPAPMAQFSAQFSMFQTIKDQL 509
Query: 385 EERTWLLHDAIQNQQNALELMMDHL 409
E+RT +L I+ QQ L + + L
Sbjct: 510 EQRTRILQANIRWQQEELHKIQEQL 534
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 75.9 bits (185), Expect = 1e-13
Identities = 43/115 (37%), Positives = 75/115 (65%), Gaps = 10/115 (8%)
Query: 477 FNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQE-KKKLQEQ 535
+ QQ+L +Q++ + EQ +LRE+ +++REQ+ Q+ +KM+EKKK QE+KMQE ++K+QEQ
Sbjct: 71 WEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQ 130
Query: 536 -----RRQKKKKLQERKKWQGQMLQKEPE----EEQQKQQLQEQPLKHNVIVGNE 581
+++K + QE K W+ + +E E E+++K Q QE+ ++ G E
Sbjct: 131 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGE 185
Score = 59.7 bits (143), Expect = 1e-08
Identities = 32/113 (28%), Positives = 73/113 (64%), Gaps = 13/113 (11%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK 530
+E + ++++ +QE+ ++EQ+ ++ EQ ++++EQ +K + +EK QE+KM E++
Sbjct: 17 EEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQE--EKMWEQEEKMWEQEEKMWEQQ 74
Query: 531 KLQEQR----------RQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
+L EQ+ R+K+++++E+K WQ Q+ + +++ Q++++QEQ K
Sbjct: 75 RLPEQKEKMWEQDERLREKEERMREQKMWQ-QVEKMREKKKTQEEKMQEQEEK 126
Score = 55.5 bits (132), Expect = 2e-07
Identities = 29/95 (30%), Positives = 66/95 (69%), Gaps = 9/95 (9%)
Query: 483 VQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKM-QEKKKLQEQ-----R 536
+++E+ ++E+++++RE+ + +REQ +K ++ +EK + QE+KM ++++K+QEQ
Sbjct: 1 MREEERMREREKKMREEEEMMREQE--EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 58
Query: 537 RQKKKKLQERKKWQGQMLQKEPEEE-QQKQQLQEQ 570
+++K QE K W+ Q L ++ E+ +Q ++L+E+
Sbjct: 59 QEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK 93
Score = 53.5 bits (127), Expect = 7e-07
Identities = 28/97 (28%), Positives = 65/97 (67%), Gaps = 7/97 (7%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKM---QEKKKLQEQ 535
++++ ++E+ ++EQ+ +++EQ +++REQ +K + +EK + QE+KM +EK QE+
Sbjct: 11 EKKMREEEEMMREQEEKMQEQEEKMREQE--EKMWEQEEKMQEQEEKMWEQEEKMWEQEE 68
Query: 536 RRQKKKKLQERKK--WQGQMLQKEPEEEQQKQQLQEQ 570
+ ++++L E+K+ W+ +E EE ++Q++ +Q
Sbjct: 69 KMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQ 105
Score = 52.0 bits (123), Expect = 2e-06
Identities = 34/181 (18%), Positives = 90/181 (49%), Gaps = 10/181 (5%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
+E E M++ ++++ E ++ + + Q E M + +K + + + E
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
K +++ ++ LP K+ + L+E +Q++ QQ + ++E
Sbjct: 62 KMWEQEEKMWEQQRLPEQKE----------KMWEQDERLREKEERMREQKMWQQVEKMRE 111
Query: 492 QQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQG 551
+++ E++Q+ E+ + Q++ ++++K+QEQ+ + ++ ++ R Q++K ++ +K QG
Sbjct: 112 KKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQG 171
Query: 552 Q 552
Q
Sbjct: 172 Q 172
Score = 48.1 bits (113), Expect = 3e-05
Identities = 37/197 (18%), Positives = 100/197 (50%), Gaps = 26/197 (13%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K++EQ EE+ W + +Q Q+ + + + +Q + + +P+++
Sbjct: 30 EQEEKMREQ-EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM--------WEQQRLPEQK 80
Query: 435 QK--QHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQ 492
+K + +++ ++ K + + K T E +++ +QE+ ++EQ
Sbjct: 81 EKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQE----------EKMQEQEEKMQEQ 130
Query: 493 QRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQ 552
+ + EQ ++++EQ +K + +EK + QE+KM+E+ +E+ + +++K+++ + G+
Sbjct: 131 EEMMWEQEEKMQEQE--EKMWEQEEKMREQEEKMREQ---EEKMQGQEEKMRDVEPAGGE 185
Query: 553 MLQKEPEEEQQKQQLQE 569
+ P++ Q++ +
Sbjct: 186 AGEGSPQDNPTAQEIMQ 202
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 74.7 bits (182), Expect = 3e-13
Identities = 71/288 (24%), Positives = 148/288 (51%), Gaps = 25/288 (8%)
Query: 312 DSVDQEGPMDQQD-PENPV--APLDQAGLMDPVDPEDSVDLGAAGASAQPLQPSSPVAYD 368
+S ++E P ++ P+ P AP+ + + + P +L QP +P ++
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQR-ELQLQQLEQQP-EPQQQPQHE 107
Query: 369 IISQ---ELELMKKLKE----QLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVI 421
+ Q LEL ++ ++ QL + H ++ +Q+ EL + H Q+Q L+ +
Sbjct: 108 QLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQ---LQPQQV 164
Query: 422 PDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQ 481
+ Q + ++ Q Q A Q ++ L + L ++ LQ+ QQQ
Sbjct: 165 QEQQRLQQQQEQLQTQQA-QEQQVLQQQEQ--------LQQQVQEQQLLQQQQEQLQQQQ 215
Query: 482 LVQQEQHLKEQQ-RQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKK 540
L+QQ++ L++QQ +Q +EQLQQ ++ +Q+Q ++Q++ Q+Q +++ L++Q+ Q +
Sbjct: 216 LLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQ 275
Query: 541 KKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQ 588
++L +++ Q Q Q++ +QQ++QLQ+Q L+ + E ++ L+
Sbjct: 276 QQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELE 323
Score = 73.2 bits (178), Expect = 9e-13
Identities = 68/242 (28%), Positives = 121/242 (50%), Gaps = 35/242 (14%)
Query: 424 LQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQ------EPCVAF 477
LQ E P+ QQ+ Q+++P PH L L + G+ Q E +
Sbjct: 91 LQQLEQQPEPQQQPQHEQLQQPQPH---------LELQQQPQQDGQQQLSQLQQEKHQSV 141
Query: 478 NQQ------QLVQQEQHLKEQQRQLREQLQQLREQ---RKVQKQKKMQEKKKLQEQKMQE 528
+ Q QL+ Q+Q L+ QQ Q +++LQQ +EQ ++ Q+Q+ +Q++++LQ+Q +QE
Sbjct: 142 HHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ-VQE 200
Query: 529 KKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQ 588
++ LQ+Q+ Q + Q++ Q + LQ++ ++QQ+Q Q+Q L G + Q+ Q
Sbjct: 201 QQLLQQQQEQLQ---QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQ 257
Query: 589 NPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGP 648
+ L LQ Q ++ Q +QQ Q + QQ+++ Q + Q P
Sbjct: 258 QQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQ----QQQQLLQQQQEQLQQ---QQLQPP 310
Query: 649 PV 650
P+
Sbjct: 311 PL 312
Score = 69.7 bits (169), Expect = 1e-11
Identities = 73/269 (27%), Positives = 132/269 (49%), Gaps = 50/269 (18%)
Query: 318 GPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQPSSPVAYDIISQELELM 377
G + Q+ E P Q P P S +GA+ A+ +P +EL+L
Sbjct: 47 GGSESQEEEEP-----QERNSSPQRPAVSAPVGASEI-AEETRPGQ--------RELQL- 91
Query: 378 KKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQ 437
++L++Q E + H+ +Q Q LEL Q+QP +QQ
Sbjct: 92 QQLEQQPEPQQQPQHEQLQQPQPHLEL-----QQQPQQ---------------DGQQQLS 131
Query: 438 HAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQ----QEQHLKEQQ 493
Q K H +++K L ++QE QQ+ +Q QEQ + +QQ
Sbjct: 132 QLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQ 191
Query: 494 RQLREQLQQLR----EQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKW 549
QL++Q+Q+ + +Q ++Q+Q+ +Q++++LQ+Q+ Q++++ Q Q++Q+ LQ++ +
Sbjct: 192 EQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQE-QLQQQQQLLLLQQQGQL 250
Query: 550 QGQMLQKEPEE------EQQKQQLQEQPL 572
Q Q+LQ++ + EQQ+ QLQ+Q L
Sbjct: 251 QQQLLQQQQAQLQQQLLEQQQAQLQQQLL 279
Score = 67.4 bits (163), Expect = 5e-11
Identities = 86/343 (25%), Positives = 154/343 (44%), Gaps = 69/343 (20%)
Query: 268 SSTVFLDTMPESPALSLQDFRGEPEVNPLYRADPVDLEFSVDQVDSVDQEGPMDQQDPEN 327
+S + +T P L LQ +PE + P + Q Q+ P QQD +
Sbjct: 75 ASEIAEETRPGQRELQLQQLEQQPEP----QQQPQHEQLQQPQPHLELQQQP--QQDGQQ 128
Query: 328 PVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQPSSPVAYDIISQELELMKKLKEQLEER 387
++ L Q E +L Q LQP QE + +++ +EQL+ +
Sbjct: 129 QLSQLQQEKHQSVHHQELKPELQLMHQQQQ-LQPQQV-------QEQQRLQQQQEQLQTQ 180
Query: 388 TWLLHDAIQNQQNALELMMDH--LQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRP 445
+Q Q+ + + + LQ+Q L+ + LQ E + ++Q +Q Q+++
Sbjct: 181 QAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQL--LQQQEQLQQQQFQQQQEQLQQQ 238
Query: 446 LPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLR-------- 497
L L L+ G+LQ+ + QQQ Q+Q L++QQ QL+
Sbjct: 239 QQ----------LLL---LQQQGQLQQQLL--QQQQAQLQQQLLEQQQAQLQQQLLLQQQ 283
Query: 498 EQLQQLREQRKVQKQKKMQEKKKLQ---------------------------EQKMQEKK 530
EQLQQ ++Q+ +Q+Q++ ++++LQ EQ+ QE +
Sbjct: 284 EQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELE 343
Query: 531 KLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
+ QE RQ++++ Q + K Q ++ Q E + EQQ+QQL++Q ++
Sbjct: 344 RQQELERQQEQR-QLQLKLQEELQQLEQQLEQQQQQLEQQEVQ 385
Score = 58.5 bits (140), Expect = 2e-08
Identities = 56/229 (24%), Positives = 114/229 (49%), Gaps = 46/229 (20%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
QE +L+++ +EQL+++ LL Q QQ + + LQ+Q L LQ +
Sbjct: 199 QEQQLLQQQQEQLQQQQ-LLQQQEQLQQQQFQQQQEQLQQQQQLLL------LQQQGQLQ 251
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
++ +Q Q+++ L + + L L+ +LQ+ QQQL+QQ+Q +
Sbjct: 252 QQLLQQQQAQLQQQLLEQQQAQ----LQQQLLLQQQEQLQQQ----QQQQLLQQQQEQLQ 303
Query: 492 QQR---------------------------QLREQLQQLREQRKVQKQKKMQEKKKLQEQ 524
QQ+ +L +Q Q+L Q+++++Q QE+++LQ +
Sbjct: 304 QQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQ---QEQRQLQLK 360
Query: 525 KMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
+E ++L++Q Q++++L E+++ Q ++ E +QQ+ QL+ P++
Sbjct: 361 LQEELQQLEQQLEQQQQQL-EQQEVQLELTPVELGAQQQEVQLELTPVQ 408
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 72.8 bits (177), Expect = 1e-12
Identities = 58/262 (22%), Positives = 135/262 (51%), Gaps = 43/262 (16%)
Query: 315 DQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQPSSPVAYDIISQEL 374
+QEG + +Q+ + +Q G M + + G + +Q + + ++
Sbjct: 175 EQEGQVREQEGQ----VREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQE----EQMGEQE 226
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E M+K +EQ+ E+ + +Q Q+ ++ + ++KQ +R E ++Q
Sbjct: 227 EQMRKQEEQMGEQ----EEQVQKQEEQVQKQEEQMRKQEEQMRE--------QEEQMREQ 274
Query: 435 QKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR 494
++Q Q ++ + + TGE QE + ++Q+ +QE+ ++EQ+
Sbjct: 275 EEQMLKQKEQ----------------TEQEEQTGE-QEEQMREQEEQMREQEEQMREQEE 317
Query: 495 QLREQLQQL--REQRKVQKQKKMQEKK----KLQEQKMQEKKKLQEQRRQKKKKLQERKK 548
Q+REQ +Q+ +E++ +++++M E+K K +EQ ++++++Q+Q Q +K+ ++ +K
Sbjct: 318 QMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRK 377
Query: 549 WQGQMLQKEPEEEQQKQQLQEQ 570
+ QM ++E + +Q++Q+ EQ
Sbjct: 378 QEEQMRKQEEQMRKQEEQMGEQ 399
Score = 64.3 bits (155), Expect = 4e-10
Identities = 40/169 (23%), Positives = 93/169 (55%), Gaps = 18/169 (10%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRK-VQKQKKMQEKKKLQEQKMQEK 529
QE + ++Q+ +QE+ +++Q+ Q+ EQ +Q+++Q + VQKQ++ K++ Q ++ +E+
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
Query: 530 KKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQN 589
+ QE++ K+K+ E+++ G+ ++ E+E+Q ++ +EQ + + + Q+ Q
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQ- 329
Query: 590 PRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQ 638
+ Q ++ EQ+ + Q+E G+QE++ Q
Sbjct: 330 ----------------EEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQ 362
Score = 57.4 bits (137), Expect = 5e-08
Identities = 43/168 (25%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK 530
QE V + Q+ +QE ++EQ+ Q+REQ Q+REQ ++++ Q +++ + Q +++
Sbjct: 50 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEG 108
Query: 531 KLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNP 590
+++EQ Q +++ + ++ +GQ+ ++E + +Q+ Q++EQ + G R Q
Sbjct: 109 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 168
Query: 591 RDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQ 638
++ V VR + Q + EQ+ Q+E G+QE++ Q
Sbjct: 169 QEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ 216
Score = 56.6 bits (135), Expect = 8e-08
Identities = 42/167 (25%), Positives = 91/167 (54%), Gaps = 11/167 (6%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQ-EK 529
QE V + Q+ +QE + EQ+ Q+ EQ +Q+ EQ ++ +K +E+ QE++M+ ++
Sbjct: 176 QEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE--EQMQKQEEQMGEQEEQMRKQE 233
Query: 530 KKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQN 589
+++ EQ Q +K+ ++ +K + QM ++E + +Q++Q++EQ + ++ E Q
Sbjct: 234 EQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQ--EEQMLKQKE------QT 285
Query: 590 PRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDE 636
++ +R + Q ++ EQ+ Q+E G+QE++
Sbjct: 286 EQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQ 332
Score = 56.2 bits (134), Expect = 1e-07
Identities = 38/180 (21%), Positives = 97/180 (53%), Gaps = 16/180 (8%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK 530
QE + ++Q+ +QE+ +++Q+ Q+++Q +Q+R+Q ++ ++ +E+ + QE++M ++K
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE--EQMREQEEQMREQEEQMLKQK 282
Query: 531 KLQEQRRQKKKKLQERKKWQGQMLQKEP---EEEQQKQQLQEQPLKHNVIVGNERVQICL 587
+ EQ Q ++ ++ ++ + QM ++E E+E+Q ++ +EQ K + ++ Q+
Sbjct: 283 EQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWE 342
Query: 588 Q-----------NPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDE 636
Q ++ + VR + Q ++ +Q+ Q+E G+Q+++
Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ 402
Score = 54.7 bits (130), Expect = 3e-07
Identities = 33/106 (31%), Positives = 72/106 (67%), Gaps = 6/106 (5%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQR-KVQKQK-KMQEKK----KLQEQ 524
QE V + Q+ +QE ++EQ+ Q+REQ Q+REQ +V++Q+ +M E++ + +EQ
Sbjct: 148 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ 207
Query: 525 KMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
++++++Q+Q Q ++ ++ +K + QM ++E + ++Q++Q+Q+Q
Sbjct: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ 253
Score = 52.8 bits (125), Expect = 1e-06
Identities = 47/173 (27%), Positives = 92/173 (53%), Gaps = 9/173 (5%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQ----RKVQKQKKMQE-KKKLQEQK 525
QE V + Q+ +QE ++EQ+ Q+REQ Q+REQ R+ + Q + QE + + QE +
Sbjct: 134 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 193
Query: 526 MQEKK-KLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQ 584
M E++ ++ EQ Q ++ ++ +K + QM ++E + +Q++Q+ EQ + V E+VQ
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQ--EEQVQKQEEQVQ 251
Query: 585 ICLQNPRDVSVPLCNHPVRFL-QAQPIVPVQRAAEQQPSGFYQDENCGQQEDE 636
+ R + + Q + ++ + EQ+ Q+E +QE++
Sbjct: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ 304
Score = 52.4 bits (124), Expect = 2e-06
Identities = 39/168 (23%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK 530
QE V + Q+ +QE ++EQ+ Q+REQ Q+REQ ++++ Q +++ + Q +++
Sbjct: 120 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEG 178
Query: 531 KLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNP 590
+++EQ Q +++ + + +GQM ++E + +Q++Q+Q+Q + R Q
Sbjct: 179 QVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE 238
Query: 591 RDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQ 638
++ V V+ + Q ++ EQ+ Q+E +Q+++++
Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286
Score = 51.6 bits (122), Expect = 3e-06
Identities = 39/171 (22%), Positives = 89/171 (52%), Gaps = 7/171 (4%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQR---KVQKQKKMQEKKKLQEQKMQ 527
QE V + Q+ +QE ++EQ+ Q+REQ Q+REQ + Q+ + +++ +++EQ+ Q
Sbjct: 127 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 186
Query: 528 EKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICL 587
+++ + Q +++ ++ E+++ G+ ++ ++E+Q + +EQ K +G + Q+
Sbjct: 187 VREQ-EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV-- 243
Query: 588 QNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQ 638
++ V +R + Q ++ EQ+ Q E Q+E +
Sbjct: 244 -QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGE 293
Score = 41.6 bits (96), Expect = 0.003
Identities = 26/87 (29%), Positives = 57/87 (65%), Gaps = 4/87 (4%)
Query: 487 QHLKEQQRQLREQLQQLREQRKVQKQKKMQE-KKKLQEQK--MQEKKKLQEQRRQKKKKL 543
+ LKE+ +L+E+LQ L E K + Q ++E K+KL+ K + ++ +++EQ Q +++
Sbjct: 7 EELKEKNAELQEELQ-LVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65
Query: 544 QERKKWQGQMLQKEPEEEQQKQQLQEQ 570
+ ++ +GQ+ ++E + +Q+ Q++EQ
Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQ 92
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 72.4 bits (176), Expect = 1e-12
Identities = 64/244 (26%), Positives = 122/244 (50%), Gaps = 42/244 (17%)
Query: 370 ISQELELMKKLKEQ-----LEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDL 424
+ ++LE K L Q L+E W + ++ Q+ + + + +Q LR +
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQE-GKM 271
Query: 425 QSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGEL----QEPCVAFNQQ 480
+ E ++Q+K+ Q K K+++ L E QE + ++
Sbjct: 272 REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEE 331
Query: 481 QLVQQEQHLKEQQRQLREQLQQLREQ---------RKVQKQKKMQEKKKL--QEQKMQEK 529
++ +QE+ L EQ++Q+REQ Q++R+Q R +K+++M+E++K+ QE+KMQE+
Sbjct: 332 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 530 KKLQEQR----------RQKKKKL---------QERKKWQGQML--QKEPEEEQQKQQLQ 568
++++E+ R++++K+ QE K+WQ Q L QKE EQ+K Q Q
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 569 EQPL 572
E+ +
Sbjct: 452 EEKI 455
Score = 68.2 bits (165), Expect = 3e-11
Identities = 34/106 (32%), Positives = 73/106 (68%), Gaps = 6/106 (5%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKV-QKQKKMQEKKKLQEQK---- 525
QE + +Q++ QE+ + EQ +LRE+ +++REQ+K+ Q+++KM+E+KK QEQ+
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
Query: 526 -MQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
+EK + +E+ R+++KK++E ++ + +K E+E++ ++ +E+
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596
Score = 63.9 bits (154), Expect = 5e-10
Identities = 44/177 (24%), Positives = 98/177 (55%), Gaps = 15/177 (8%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK 530
QE + ++++ +QE+ L+EQ+ ++REQ +++R Q K + ++ +++ + QE++++E+K
Sbjct: 246 QEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEK--RLREQEKELREQEKELREQK 303
Query: 531 KLQEQRRQKKKKLQERKKWQGQMLQKEPEEE---------QQKQQLQEQPLKHNVIVGNE 581
KL+EQ Q ++ QE K W+ + +E EE+ +Q++Q++EQ K + E
Sbjct: 304 KLREQEEQMQE--QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK--MRDQEE 359
Query: 582 RVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQ 638
R+ + R+ + + Q + + +R E++ ++E +QE++ Q
Sbjct: 360 RMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQ 416
Score = 61.6 bits (148), Expect = 3e-09
Identities = 62/294 (21%), Positives = 139/294 (47%), Gaps = 61/294 (20%)
Query: 372 QELELMKKLKEQ------LEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQ 425
+EL KKL+EQ EE+ W + ++ Q+ + + L +Q +R
Sbjct: 297 KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR-------- 348
Query: 426 SSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQ 485
+Q+++ Q +R + ++ + ++E + Q++ +Q+
Sbjct: 349 -------EQEQKMRDQEERMWEQDERLR-----------EKEERMREQEKMWEQEEKMQE 390
Query: 486 EQHLKEQQRQLREQLQQLREQ-RKVQKQKK---MQEKKKLQEQKMQEKK-------KLQE 534
E+ ++E+++++RE+ + +REQ K+QKQ++ QE+K+ Q+Q++ E+K K+QE
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQE 450
Query: 535 Q-----------RRQKKKKLQERKKWQGQMLQKEPE---EEQQKQQLQEQPLKHNVIVGN 580
Q R Q++ QE+K W+ + ++++ + E+++K + QEQ +
Sbjct: 451 QEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ----E 506
Query: 581 ERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQE 634
ER+ + R+ + + Q + + ++ EQ+ + Q+E ++E
Sbjct: 507 ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Score = 60.8 bits (146), Expect = 5e-09
Identities = 48/220 (21%), Positives = 116/220 (52%), Gaps = 27/220 (12%)
Query: 378 KKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQ 437
+K++EQ E++ W + +++Q+ + + + +Q LR + + E QQ++
Sbjct: 479 EKMREQ-EDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE---KEERMREQKKMWQQEE 534
Query: 438 HAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLR 497
+ K+ K ++ ++E ++++ ++E+ ++EQ+ +++
Sbjct: 535 KMREEKKTQEQEKKT-----WDQEEKMREEERMRE-----REKKMREEEEMMREQEEKMQ 584
Query: 498 EQLQQLREQRKV--QKQKKMQEKKKL---QEQKM---QEKKKLQEQ-----RRQKKKKLQ 544
EQ +++REQ + ++++KMQE+++ QE+KM +E+ K+QEQ +++K + Q
Sbjct: 585 EQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQ 644
Query: 545 ERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQ 584
E K W+ + +E EE+ ++Q+ + Q + + E++Q
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Score = 60.5 bits (145), Expect = 6e-09
Identities = 34/116 (29%), Positives = 76/116 (65%), Gaps = 19/116 (16%)
Query: 477 FNQQQLVQQEQHLKEQQRQLREQLQQL---------REQRKVQKQKKMQEKKKL--QEQK 525
+ Q+++ +QE + EQ+ ++R+Q Q++ +++R +K+++M+E+KK+ QE+K
Sbjct: 476 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEK 535
Query: 526 MQEKKKLQEQRR-----QKKKKLQERKKWQGQMLQKEPE---EEQQKQQLQEQPLK 573
M+E+KK QEQ + ++K + +ER + + + +++E E E+++K Q QE+ ++
Sbjct: 536 MREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Score = 59.3 bits (142), Expect = 1e-08
Identities = 46/208 (22%), Positives = 107/208 (51%), Gaps = 9/208 (4%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVV-IPDLQSSEAV 430
Q E +K+++Q E++ W + + Q L + +++Q + + + + ++
Sbjct: 487 QMWEQEEKMRDQ-EQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Query: 431 PKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLK 490
KK Q + ++ K + + + QE + ++++ +QE+ ++
Sbjct: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ 605
Query: 491 EQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQE-KKKLQEQ----RRQKKKKLQE 545
EQ+ ++ EQ +++ EQ + K ++ +E QE+KMQE ++K+ EQ R Q++K ++
Sbjct: 606 EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665
Query: 546 RKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
+K QGQ +++ E+++K Q QE+ ++
Sbjct: 666 EEKMQGQ--EEKMREQEEKMQGQEEKMR 691
Score = 58.2 bits (139), Expect = 3e-08
Identities = 35/104 (33%), Positives = 76/104 (73%), Gaps = 13/104 (12%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQL--REQRKVQKQKKMQEKKKLQEQKM-QEKKKLQEQ 535
Q+++ +QE+ L+EQ++++R+Q +++ +E+R +++ KM+E QE+KM +++K+L+EQ
Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE----QEEKMRRQEKRLREQ 288
Query: 536 R---RQKKKKLQERKKWQGQMLQKEPEEE---QQKQQLQEQPLK 573
R+++K+L+E+KK + Q Q + +EE +Q+++++EQ K
Sbjct: 289 EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Score = 56.6 bits (135), Expect = 8e-08
Identities = 48/218 (22%), Positives = 108/218 (49%), Gaps = 33/218 (15%)
Query: 378 KKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQ 437
KK +EQ E++TW + ++ ++ E ++++ +R + E + ++++K
Sbjct: 540 KKTQEQ-EKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 438 HAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLR 497
+ K K K + +E + ++ + +QE+ ++EQ+ ++
Sbjct: 598 WEQEEKMQEQEEK--------MWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649
Query: 498 EQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKK----LQEQRRQKKKKL--QERKKW-- 549
EQ +++REQ +K ++ +EK + QE+KM+E+++ +E+ R++++K+ QE K W
Sbjct: 650 EQEEKMREQE--EKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQ 707
Query: 550 -------------QGQMLQKEPEEEQQKQQLQEQPLKH 574
Q +M +KE QK+++QE+ +H
Sbjct: 708 EEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEH 745
Score = 53.1 bits (126), Expect = 9e-07
Identities = 39/175 (22%), Positives = 97/175 (55%), Gaps = 22/175 (12%)
Query: 477 FNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKM----------QEKKKLQEQKM 526
+ Q+++ +QE+ + EQ+ ++R+Q + +++K+ +Q+KM +EK + QEQKM
Sbjct: 443 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
Query: 527 QEKKKLQ----EQRRQKKKKLQERKK-WQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNE 581
++++ E+ R+K+++++E+KK WQ + +K EE++ ++Q ++ + + E
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQE--EKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 582 RVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDE 636
R++ + R+ + + + + ++ EQ+ + Q+E +QE++
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQE-----EKMREQEEKMWEQEEKMQEQEEK 610
Score = 51.2 bits (121), Expect = 4e-06
Identities = 42/192 (21%), Positives = 100/192 (52%), Gaps = 31/192 (16%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K++EQ EE+ W + +Q Q+ + + + +Q + +Q E + +Q
Sbjct: 585 EQEEKMREQ-EEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK------MQEQEEMMWEQ 637
Query: 435 QKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR 494
+++ Q ++ + ++ QE + ++++ QE+ ++EQ+
Sbjct: 638 EEKMQEQEEKMWEQEEKMR----------------EQEEKMREQEEKMQGQEEKMREQEE 681
Query: 495 QLREQLQQLREQRKVQKQKKMQEKKKLQEQKM---QEKKKLQEQRRQKKKKLQERKKWQG 551
+++ Q +++REQ +K + +EK QE+KM +EK QE+ R+K+++++++K+
Sbjct: 682 KMQGQEEKMREQE--EKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE--- 736
Query: 552 QMLQKEPEEEQQ 563
+M ++ PE E++
Sbjct: 737 KMQERLPEHEER 748
Score = 39.3 bits (90), Expect = 0.014
Identities = 30/119 (25%), Positives = 70/119 (58%), Gaps = 16/119 (13%)
Query: 465 KNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLRE--------QLQQLREQRKVQKQKKMQ 516
K ELQE + + + + + ++KE +R+L Q L+E+ Q+++ +
Sbjct: 187 KKNAELQEK-LRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELRE 245
Query: 517 EKKKLQEQKMQEKKKLQEQR-RQKKKKLQER----KKWQGQMLQKEPEEEQQKQQLQEQ 570
++KK+++Q +EK QE+R R+++ K++E+ ++ + ++ ++E E +Q+++L+EQ
Sbjct: 246 QEKKIRKQ--EEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
Score = 32.7 bits (73), Expect = 1.3
Identities = 29/107 (27%), Positives = 56/107 (52%), Gaps = 24/107 (22%)
Query: 487 QHLKEQQRQLREQLQQLREQRKVQKQKKMQE-KKKLQEQK-----MQEKKKLQEQRRQKK 540
+ LK++ +L+E+L+ L E K + Q ++E K+KL+ K +Q +E RQ++
Sbjct: 183 EELKKKNAELQEKLR-LAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEE 241
Query: 541 KK--------LQERKKW---------QGQMLQKEPEEEQQKQQLQEQ 570
+ QE K W +G+M ++E + +Q+++L+EQ
Sbjct: 242 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQ 288
Score = 32.3 bits (72), Expect = 1.7
Identities = 32/156 (20%), Positives = 74/156 (47%), Gaps = 24/156 (15%)
Query: 373 ELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPK 432
E E K++EQ EE W + +Q Q+ + + +++Q +R +Q E +
Sbjct: 620 EQEEEDKMQEQ-EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQE-EKMQGQEEKMR 677
Query: 433 KQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQ 492
+Q+++ GQ ++ + ++ QE + ++++ QE+ + Q
Sbjct: 678 EQEEKMQGQEEKMREQEEKMRG----------------QEEKMWGQEEKMWGQEEKMWGQ 721
Query: 493 QRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQE 528
+ ++RE+ +++R+Q+ +KMQE+ E++ E
Sbjct: 722 E-EMREKEERIRDQK-----EKMQERLPEHEERCSE 751
Score = 30.4 bits (67), Expect = 6.5
Identities = 29/122 (23%), Positives = 62/122 (50%), Gaps = 11/122 (9%)
Query: 460 LSNSLKNTGELQEPCVAFN--QQQLVQQEQHLKEQQRQLREQLQQ--LREQRKVQKQKKM 515
L +S GELQ A + ++ + + L +++ L +L + + + +K ++
Sbjct: 133 LHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL 192
Query: 516 QEKKKLQEQKMQEKKKLQEQRRQKKKKLQERK----KWQGQMLQKEPEEEQQKQQLQEQP 571
QEK +L E EK ++Q ++ K+KL+ K + Q LQ+E ++++ + QE+
Sbjct: 193 QEKLRLAES---EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKK 249
Query: 572 LK 573
++
Sbjct: 250 IR 251
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 72.0 bits (175), Expect = 2e-12
Identities = 50/191 (26%), Positives = 104/191 (54%), Gaps = 10/191 (5%)
Query: 397 NQQNALELMMDHLQKQP--NTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKC 454
++ + +EL+ HLQ+Q R +++ S PK KQ RPL P V
Sbjct: 42 SEVSTVELL--HLQQQQALQAARQLLLQQQTSGLKSPKSSDKQ------RPLQVPVSVAM 93
Query: 455 FCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKK 514
++ Q+ Q L+QQ+Q + QQ+QL+E ++ +EQ +Q ++
Sbjct: 94 MTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQ 153
Query: 515 MQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKH 574
Q++++ Q+Q+ Q++++ Q+Q++Q++++ Q++++ Q Q K+ +E+QQ+QQ Q+Q
Sbjct: 154 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 213
Query: 575 NVIVGNERVQI 585
++ + +Q+
Sbjct: 214 QLVFQQQLLQM 224
Score = 59.7 bits (143), Expect = 1e-08
Identities = 30/93 (32%), Positives = 65/93 (69%), Gaps = 1/93 (1%)
Query: 481 QLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKK 540
QL+QQ+Q ++QQ+Q ++Q QQ ++Q++ Q+Q++ Q++++ Q+ ++ K+ Q+Q++Q++
Sbjct: 149 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 208
Query: 541 KKLQERKKWQGQMLQKEPEEEQQK-QQLQEQPL 572
+ ++ +Q Q+LQ + ++QQ LQ Q L
Sbjct: 209 QLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGL 241
Score = 56.2 bits (134), Expect = 1e-07
Identities = 34/108 (31%), Positives = 70/108 (64%), Gaps = 9/108 (8%)
Query: 471 QEPCVAFNQQQLV-----QQEQ---HLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQ 522
Q+ V QQQL QQEQ L +QQ+Q ++Q QQ ++Q++ Q+Q++ Q++++ Q
Sbjct: 124 QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 183
Query: 523 EQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
+Q+ Q+++ +Q ++++++ Q++++ Q L + ++ Q QQLQ+Q
Sbjct: 184 QQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQ-QQLLQMQQLQQQ 230
Score = 37.7 bits (86), Expect = 0.041
Identities = 37/182 (20%), Positives = 78/182 (42%), Gaps = 44/182 (24%)
Query: 358 PLQPSSPVAYDIIS-QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTL 416
P Q + ++S Q+L+ + + ++ + + L + + QQ L L + Q+Q
Sbjct: 101 PQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ-- 158
Query: 417 RHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVA 476
Q + ++QQ+Q Q ++
Sbjct: 159 --------QQQQQQQQQQQQQQQQQQQQ-------------------------------- 178
Query: 477 FNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQR 536
QQQ QQ+Q + +Q +EQ QQ ++Q+++ Q+ + +++ LQ Q++Q+++ L +
Sbjct: 179 -QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ 237
Query: 537 RQ 538
RQ
Sbjct: 238 RQ 239
Score = 37.0 bits (84), Expect = 0.070
Identities = 49/229 (21%), Positives = 94/229 (41%), Gaps = 64/229 (27%)
Query: 483 VQQEQHLKE-QQRQLREQLQQLREQRKVQKQKKMQ------------------------- 516
+QQ+Q L+ +Q L++Q L+ + KQ+ +Q
Sbjct: 52 LQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQ 111
Query: 517 -------------------EKKKLQE--QKMQEKKKLQ--EQRRQKKKKLQERKKWQGQM 553
++++LQE +K QE+ LQ +Q++Q++++ Q++++ Q Q
Sbjct: 112 VLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQ 171
Query: 554 LQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPV 613
Q++ +++QQ+QQ Q+Q +H E+ Q Q + L AQ +V
Sbjct: 172 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ-------------LAAQQLVFQ 218
Query: 614 QRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPVNQLPLIDTSNSE 662
Q+ + Q Q ++ + + P PV LP S +E
Sbjct: 219 QQLLQMQQ--LQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLSPAE 265
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 69.3 bits (168), Expect = 1e-11
Identities = 55/216 (25%), Positives = 112/216 (51%), Gaps = 35/216 (16%)
Query: 397 NQQNALELMMDHLQKQP--NTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPH--PKDV 452
++ + +EL+ HLQ+Q R +++ S PK KQ RPL P+
Sbjct: 42 SEVSTVELL--HLQQQQALQAARQLLLQQQTSGLKSPKSSDKQ------RPLQELLPETK 93
Query: 453 KCFCGLSLSN-------SLKNTGELQEPCVAFNQQQ----------------LVQQEQHL 489
C CG S + ++ + + P V QQ L+QQ+Q +
Sbjct: 94 LCICGHSSGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAV 153
Query: 490 KEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKW 549
QQ+QL+E ++ +EQ +Q ++ Q++++ Q+Q+ Q++++ Q+Q++Q++++ Q++++
Sbjct: 154 MLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 213
Query: 550 QGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQI 585
Q Q K+ +E+QQ+QQ Q+Q ++ + +Q+
Sbjct: 214 QQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 249
Score = 59.7 bits (143), Expect = 1e-08
Identities = 30/93 (32%), Positives = 65/93 (69%), Gaps = 1/93 (1%)
Query: 481 QLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKK 540
QL+QQ+Q ++QQ+Q ++Q QQ ++Q++ Q+Q++ Q++++ Q+ ++ K+ Q+Q++Q++
Sbjct: 174 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 233
Query: 541 KKLQERKKWQGQMLQKEPEEEQQK-QQLQEQPL 572
+ ++ +Q Q+LQ + ++QQ LQ Q L
Sbjct: 234 QLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGL 266
Score = 37.7 bits (86), Expect = 0.041
Identities = 37/182 (20%), Positives = 78/182 (42%), Gaps = 44/182 (24%)
Query: 358 PLQPSSPVAYDIIS-QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTL 416
P Q + ++S Q+L+ + + ++ + + L + + QQ L L + Q+Q
Sbjct: 126 PQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ-- 183
Query: 417 RHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVA 476
Q + ++QQ+Q Q ++
Sbjct: 184 --------QQQQQQQQQQQQQQQQQQQQ-------------------------------- 203
Query: 477 FNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQR 536
QQQ QQ+Q + +Q +EQ QQ ++Q+++ Q+ + +++ LQ Q++Q+++ L +
Sbjct: 204 -QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ 262
Query: 537 RQ 538
RQ
Sbjct: 263 RQ 264
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 69.3 bits (168), Expect = 1e-11
Identities = 54/216 (25%), Positives = 116/216 (53%), Gaps = 42/216 (19%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E KK+++Q EE+ W + ++ Q+ + + + +Q LR +
Sbjct: 283 EQEKKIRKQ-EEKMWRQEERLREQEGKMREQEEKMWRQEKRLR----------------E 325
Query: 435 QKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGEL---QEPCVAFNQQQLVQQEQHLKE 491
Q++ + ++ L K+++ ++ E QE + ++++ +QE+ L E
Sbjct: 326 QEKELREQEKELREQKELR-----EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE 380
Query: 492 QQRQLREQLQQLREQ---------RKVQKQKKMQEKKKLQEQ--KMQEKKKLQEQR---R 537
Q++Q+REQ Q++R+Q R +K+++M+E++K+ EQ KM+E+KK+QEQ R
Sbjct: 381 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTR 440
Query: 538 QKKKKLQERKKWQGQMLQKEPEEE---QQKQQLQEQ 570
+++K+QE ++ + + + EEE +Q++++Q+Q
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQ 476
Score = 62.0 bits (149), Expect = 2e-09
Identities = 58/213 (27%), Positives = 114/213 (53%), Gaps = 46/213 (21%)
Query: 359 LQPSSPVAYDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRH 418
LQ P+A S+ +K+LK +LE +LL Q Q N L+ + + +Q LR
Sbjct: 230 LQEKLPLAESEKSEIQLNVKELKRKLERAKFLLP---QVQTNTLQ---EEMWRQEEELRE 283
Query: 419 VVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFN 478
E +KQ+++ Q +R + G+++E
Sbjct: 284 --------QEKKIRKQEEKMWRQEER------------------LREQEGKMRE-----Q 312
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKM-QEKKKLQEQRR 537
++++ +QE+ L+EQ+++LREQ ++LREQ+++++Q +E+ + QE+KM ++++K++EQ
Sbjct: 313 EEKMWRQEKRLREQEKELREQEKELREQKELREQ---EEQMQEQEEKMWEQEEKMREQ-- 367
Query: 538 QKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
++K QE + W+ +K+ E++QK + QE+
Sbjct: 368 EEKMWRQEERLWE---QEKQMREQEQKMRDQEE 397
Score = 61.6 bits (148), Expect = 3e-09
Identities = 47/204 (23%), Positives = 106/204 (51%), Gaps = 22/204 (10%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
QE + KK +EQ E++TW + ++ ++ E ++++ +R + E +
Sbjct: 563 QEERMEKKTQEQ-EKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
++++K + K K + + E +E + QQ+L +Q++ L E
Sbjct: 621 EQEEKMWEQEEKMQEQEEK---------MWEQEEKMWEQEEKM--WEQQRLPEQKEKLWE 669
Query: 492 -----QQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQER 546
+Q +++EQ +++ EQ K++K+ + QEKK ++KM+E +E R+++KK++E
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE----EESMREREKKMREE 725
Query: 547 KKWQGQMLQKEPEEEQQKQQLQEQ 570
++ + +K E+E++ Q+ +E+
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEE 749
Score = 59.7 bits (143), Expect = 1e-08
Identities = 30/104 (28%), Positives = 71/104 (68%), Gaps = 8/104 (7%)
Query: 477 FNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL---QEQKMQEKKKL- 532
+ Q+++ +QE+ + EQ+ ++R+Q + +++K+ +Q+KM+E++ QE+KM+++++
Sbjct: 501 WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 533 --QEQRRQKKKKLQERKKW--QGQMLQKEPEEEQQKQQLQEQPL 572
QE+R +KK + QE+K W + +M ++E E++K+ +E+ +
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 604
Score = 57.8 bits (138), Expect = 4e-08
Identities = 48/191 (25%), Positives = 107/191 (56%), Gaps = 18/191 (9%)
Query: 394 AIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVK 453
A+ + + ++ L K+ + L + + ++E + KK + Q K PL + +
Sbjct: 187 AVSTRHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAEL---QEKLPLAESEKSE 243
Query: 454 CFCGLSLSNSLKNTGELQEPCVAFN--QQQLVQQEQHLKEQQRQLREQLQQL--REQRKV 509
+ + P V N Q+++ +QE+ L+EQ++++R+Q +++ +E+R
Sbjct: 244 IQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLR 303
Query: 510 QKQKKMQEKKKLQEQKM-QEKKKLQEQR---RQKKKKLQERKKWQGQMLQKEPEEE---Q 562
+++ KM+E QE+KM +++K+L+EQ R+++K+L+E+K+ + Q Q + +EE +
Sbjct: 304 EQEGKMRE----QEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWE 359
Query: 563 QKQQLQEQPLK 573
Q+++++EQ K
Sbjct: 360 QEEKMREQEEK 370
Score = 56.2 bits (134), Expect = 1e-07
Identities = 28/108 (25%), Positives = 69/108 (63%), Gaps = 7/108 (6%)
Query: 477 FNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQR 536
+ Q+++ +QE + EQ+ ++R+Q Q++ +Q + ++K +++KK +Q +EK + +E+
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQ--EEKMREEERM 591
Query: 537 RQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQ 584
R+++KK++E ++ + +E EE+ Q+Q+ + Q + + E++Q
Sbjct: 592 REREKKMREEEE-----MMREQEEKMQEQEEKMQEQEEKMWEQEEKMQ 634
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/292 (18%), Positives = 139/292 (47%), Gaps = 38/292 (13%)
Query: 372 QELELMKKLKEQL---EERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVV--IPDLQS 426
++ E M++ +E++ EER W ++ Q+ + + + +Q LR + + +
Sbjct: 359 EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK 418
Query: 427 SEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQE 486
+K +++ Q + ++ K + K E +E + ++++ +QE
Sbjct: 419 MWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMRE-EEETMREQEEKMQKQE 477
Query: 487 QHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL----------------QEQKMQEKK 530
+++ EQ+ + +Q + ++ K+ +Q+KMQE+++ QE+KM ++
Sbjct: 478 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 537
Query: 531 KLQEQ-----RRQKKKKLQERKKW-QGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQ 584
K++EQ +++K + QE+K W Q + ++K+ +E+++K QE+ ++ ER++
Sbjct: 538 KMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMRE-----EERMR 592
Query: 585 ICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDE 636
+ R+ + + + + ++ EQ+ + Q+E +QE++
Sbjct: 593 EREKKMREEEEMMREQEEKMQEQE-----EKMQEQEEKMWEQEEKMQEQEEK 639
Score = 52.4 bits (124), Expect = 2e-06
Identities = 56/235 (23%), Positives = 111/235 (47%), Gaps = 41/235 (17%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNA---LELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
E +K+ EQ EE+ W + + QQ E + +H + Q + E +
Sbjct: 635 EQEEKMWEQ-EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGEL---QEPCVAFNQQQLVQQEQH 488
KK Q+Q K+ K + ++ E+ QE + ++++ +QE+
Sbjct: 694 KKTQEQE----KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Query: 489 LKEQQRQLREQLQQLREQRKVQKQK-------KMQEKKKL--QEQKM---QEKKKLQEQR 536
+ EQ+ ++ EQ +++ EQ+++ +QK KMQE++K+ QE+KM +EK + QE++
Sbjct: 750 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEK 809
Query: 537 ---RQKKKKLQERKKW---------------QGQMLQKEPEEEQQKQQLQEQPLK 573
+++K + QE K W Q + + + E+ ++K Q QE+ ++
Sbjct: 810 MRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMR 864
Score = 52.4 bits (124), Expect = 2e-06
Identities = 47/229 (20%), Positives = 106/229 (46%), Gaps = 30/229 (13%)
Query: 373 ELELMKKLKEQLEERTW---------LLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPD 423
E E M+K ++ E++TW + + + + E+M + +K + +
Sbjct: 688 EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747
Query: 424 LQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLV 483
+ E K +++ ++ LP K+ L ++QE Q+++
Sbjct: 748 EEMWEQEEKMWEQEEKMWEQQRLPEQKE-----------KLWEHEKMQE------QEKIW 790
Query: 484 QQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKM--QEKKKLQEQRRQKKK 541
+QE+ +++Q+ ++R Q +++R Q +K + +EK QE+KM QE+K ++ + +
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQE--EKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQ 848
Query: 542 KLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNP 590
+ + +K QGQ + +EE+ + Q ++ + + G E C+ +P
Sbjct: 849 EEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYCVGSP 897
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 69.3 bits (168), Expect = 1e-11
Identities = 47/158 (29%), Positives = 92/158 (58%), Gaps = 16/158 (10%)
Query: 429 AVPKKQQKQHAGQVKRP-LPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQ 487
A ++QQ+QH Q L H + S + G LQ+ QQQ +QQ+Q
Sbjct: 3855 AQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQ----LQQQQQLQQQQ 3910
Query: 488 HLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERK 547
L++QQ+Q +Q QQL++Q+ Q+Q++ Q +++ Q+Q Q++++LQ+Q++Q++++ Q+++
Sbjct: 3911 QLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQ 3970
Query: 548 KWQGQMLQKE------PEEEQQKQ-----QLQEQPLKH 574
+ Q L + P+++QQ+Q + +PL+H
Sbjct: 3971 QQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQH 4008
Score = 62.0 bits (149), Expect = 2e-09
Identities = 115/514 (22%), Positives = 205/514 (39%), Gaps = 94/514 (18%)
Query: 325 PENPVAPLDQAGLMDPVDPEDSVDLGAAGASAQPLQPSSP--VAYDIISQELELMKKLKE 382
P P P L + S G AG+ A P P +A + + L+++ +
Sbjct: 3665 PGQPGGPFLNTALAQQQQQQHS---GGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQL 3721
Query: 383 QLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVI-------PDLQSSEAV-PKKQ 434
QL+++ L +Q QQ Q+Q + L V I P +Q+++A+ PK Q
Sbjct: 3722 QLQQQRMQLAQKLQQQQQ-------QQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQ 3774
Query: 435 ------------------------------------QKQHAGQVKRPLPHPKDVKCFCGL 458
Q+QH G + PH + + +
Sbjct: 3775 GLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRV 3834
Query: 459 SLSNSLKNTGE--LQEPCVAFNQQQLVQQEQ---------HLKEQ------QRQLREQ-- 499
S L G+ + V QQQ QQ Q HL++ Q +L Q
Sbjct: 3835 LSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPM 3894
Query: 500 --LQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKE 557
LQQL++Q+++Q+Q+++Q++++ Q Q+ Q+ ++ Q Q++Q++++LQ++++ Q Q Q++
Sbjct: 3895 GSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQ 3954
Query: 558 ---PEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQ 614
+++QQ+Q Q+Q + ++ R + Q + V L P P+Q
Sbjct: 3955 LQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALG-------PGMPAKPLQ 4007
Query: 615 RAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPVNQ-LPLIDTSNSEAISSSSIPQFP 673
+ G +Q + EA +GP +Q PL + E++++ P
Sbjct: 4008 HFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKP 4067
Query: 674 ITSDSTISTLETPQDYIRLWQELSDSLGPVVQVNTWSCDEQGTLH--GQPTYHQVQVSEV 731
S + L PQ Q S L P +++ + LH G ++ Q+ S
Sbjct: 4068 SLSGDSQLLLVQPQPQP---QPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLG-SGS 4123
Query: 732 GVEGPPDPQAFQGPAAYQPDQMRSAEQTRLMPAE 765
E P P+ DQ S Q L P +
Sbjct: 4124 SSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQ 4157
Score = 52.8 bits (125), Expect = 1e-06
Identities = 99/463 (21%), Positives = 173/463 (37%), Gaps = 73/463 (15%)
Query: 319 PMDQQDPENPVAPLD---QAGLMDPVDPEDSVDLGAAGASAQPLQPSSPVAYDIISQELE 375
PM P + P Q L + P+ +D AA P+ + VA
Sbjct: 3381 PMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVA--------- 3431
Query: 376 LMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQ 435
+K +K+ + + + + + QQ + L+ L P++ DLQ+ A Q+
Sbjct: 3432 -LKGIKKVMAQGSIGVAPGMNRQQ--VSLLAQRLSGGPSS-------DLQNHVAAGSGQE 3481
Query: 436 KQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQ 495
+ AG +P P+P G + E ++ L +Q L+ Q +
Sbjct: 3482 RS-AGDPSQPRPNPPTFA-------------QGVINEADQRQYEEWLFHTQQLLQMQLKV 3527
Query: 496 LREQLQQLREQRKVQKQKKMQEKKKLQE------QKM----QEKKKLQEQRRQKKKKLQE 545
L EQ+ R+ RK K+ KK +E +K+ +++ K+Q+Q Q +K+ +E
Sbjct: 3528 LEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKE 3587
Query: 546 RKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRFL 605
+ K+ +++QQ+QQ Q+Q + ++ ++ + P + L H ++
Sbjct: 3588 HTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQL---LPGHGLQPP 3644
Query: 606 QAQP--------IVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPP----VNQL 653
Q P + P A QP G + + QQ+ + S + GP L
Sbjct: 3645 QGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNL 3704
Query: 654 PLIDTSNSEAISSSSIPQFPITSDSTISTLETPQDYIRLWQEL--------SDSLGPVVQ 705
L + Q L+ Q + Q L GP VQ
Sbjct: 3705 ALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQ 3764
Query: 706 VN-TWSCDEQGTLHGQPTYHQ-VQVSEVGVEGPPDPQAFQGPA 746
N QG + P+ HQ + V ++ + P PQ GPA
Sbjct: 3765 TNQALGPKPQGLM--PPSSHQGLLVQQLSPQPPQGPQGMLGPA 3805
Score = 32.3 bits (72), Expect = 1.7
Identities = 59/294 (20%), Positives = 113/294 (38%), Gaps = 17/294 (5%)
Query: 481 QLVQQEQHLKEQQR-QLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQK 539
+L+Q+ Q +QQR QL ++LQQ ++Q++ Q+Q + + Q+Q+ + + K
Sbjct: 3714 RLLQERQLQLQQQRMQLAQKLQQ-QQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPK 3772
Query: 540 KKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCN 599
+ L QG ++Q+ + Q Q P + V+ + Q P +
Sbjct: 3773 PQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGP--------H 3824
Query: 600 HPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPVNQLPLIDTS 659
V Q++ + Q A + Q ++ QQ+ + Q + G Q L+ S
Sbjct: 3825 RQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHS 3884
Query: 660 NSEAISSSSIPQFPITSDSTISTLETPQDYIRLWQELSDSLGPVVQVNTWSCDEQGTLH- 718
+S+ P+ S + + Q +L Q+ L Q+ +Q
Sbjct: 3885 GQPKLSAQ-----PMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQ 3939
Query: 719 -GQPTYHQVQVSEVGVEGPPDPQAFQGPAAYQPDQMRSAEQTRLMPAEQRDSNK 771
Q Q+Q + ++ Q Q Q QM Q+R + + Q+ +
Sbjct: 3940 LQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQ 3993
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 67.8 bits (164), Expect = 4e-11
Identities = 51/214 (23%), Positives = 107/214 (50%), Gaps = 20/214 (9%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
QE + +EQ E R WL + + +++ E L++ R L+ E
Sbjct: 440 QERREQRLKREQEERRDWLKREE-ETERHEQERRKQQLKRDQEEERRERWLKLEEEER-- 496
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
++QQ++ Q++R ++ + LK E + QQ ++ EQ L+
Sbjct: 497 REQQERREQQLRREQEERREQR----------LKRQEEEER------LQQRLRSEQQLRR 540
Query: 492 QQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQG 551
+Q + REQL + E+++++++++ Q K+ QE++ + K +E+RRQ++ K ++ ++ +
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE- 599
Query: 552 QMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQI 585
Q L++E E ++++ +EQ LK R Q+
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Score = 61.6 bits (148), Expect = 3e-09
Identities = 29/96 (30%), Positives = 72/96 (75%), Gaps = 2/96 (2%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ 538
+Q+ QQ+Q L+ +Q+ R+Q ++ REQ++ +++++ + +++ +E++ Q+ ++ QE+RR+
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQE-ERREQQERREQQEERREQQLRREQEERRE 348
Query: 539 KKKKLQERKKWQGQMLQKEPEEEQQKQQL-QEQPLK 573
++ + ++ ++ + Q L++E EEE+++QQL +EQ L+
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Score = 61.6 bits (148), Expect = 3e-09
Identities = 32/98 (32%), Positives = 67/98 (68%), Gaps = 5/98 (5%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ 538
+QQL +++Q +EQQ + +QL++ ++ R+ Q+ ++ Q+ ++ QE++ E+K QE+R Q
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQ 445
Query: 539 K-KKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHN 575
+ K++ +ER+ W L++E E E+ +Q+ ++Q LK +
Sbjct: 446 RLKREQEERRDW----LKREEETERHEQERRKQQLKRD 479
Score = 60.8 bits (146), Expect = 5e-09
Identities = 27/95 (28%), Positives = 73/95 (76%), Gaps = 3/95 (3%)
Query: 479 QQQLVQQEQHLKEQQRQLRE-QLQQLREQRKV--QKQKKMQEKKKLQEQKMQEKKKLQEQ 535
Q++ Q+++ L+E++ QLR+ + Q+LR +R+ Q+Q++++ +++L+ ++ +E+++ QE+
Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE 320
Query: 536 RRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
RR+++++ +++++ + Q L++E EE +++Q +EQ
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQ 355
Score = 59.7 bits (143), Expect = 1e-08
Identities = 29/102 (28%), Positives = 72/102 (70%), Gaps = 7/102 (6%)
Query: 469 ELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQE 528
E +E +Q+L ++ Q ++QQ++LR + QQLR +++ +++++ +E+++ QE++ Q+
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRRE-QQLRRKQEEERREQQEERREQQERREQQ 331
Query: 529 KKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
+++ ++Q R+++++ +E Q L++E EEE+++QQL+ +
Sbjct: 332 EERREQQLRREQEERRE------QQLRREQEEERREQQLRRE 367
Score = 58.5 bits (140), Expect = 2e-08
Identities = 48/179 (26%), Positives = 98/179 (54%), Gaps = 17/179 (9%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLR--EQLQQLREQRKVQKQKKMQEKKKLQEQKM-- 526
QEP +++ +++EQ L QQRQ + ++ QQLR Q + Q++++ +++K +E+++
Sbjct: 1511 QEP-----ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Query: 527 -QEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQ--KQQLQEQPLKHNVIVGNERV 583
+E+++L Q R +K +L+E+K + + +K E+EQQ +Q+ Q+Q + E
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625
Query: 584 QICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQ----QPSGFYQDENCGQQEDESQ 638
Q+ LQ + + +FL+ +P + Q +Q + F ++E Q+ +E Q
Sbjct: 1626 QL-LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Score = 56.2 bits (134), Expect = 1e-07
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 29/173 (16%)
Query: 479 QQQLVQQ--EQHLKEQQR--QLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQE 534
++QL+Q+ EQ L+ Q+R + RE+ QQLR Q + ++K +QE+++L+ Q+++ K + +E
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER--ERKFLQEEQQLRRQELERKFREEE 1729
Query: 535 QRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVS 594
Q RQ+ ++ Q R++ + +K EEEQ + + +EQ L+ R + L+ R+
Sbjct: 1730 QLRQETEQEQLRRQ---ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE-- 1784
Query: 595 VPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQG 647
Q+ Q+ +++E +QE E Q P+ G
Sbjct: 1785 ------------------EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDG 1819
Score = 55.8 bits (133), Expect = 1e-07
Identities = 50/205 (24%), Positives = 108/205 (52%), Gaps = 32/205 (15%)
Query: 372 QELELMKKLK-EQLEERTWLLHDAIQNQQNAL---ELMMDHLQKQPNTLRHVVIPDLQSS 427
Q+L ++L+ EQ EER H+ + +Q E D L+++ T RH
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH--------- 467
Query: 428 EAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQ 487
+Q++ Q+KR + + L + E QE ++Q +++EQ
Sbjct: 468 ------EQERRKQQLKRDQEEERRERW-----LKLEEEERREQQE-----RREQQLRREQ 511
Query: 488 HLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQ--KMQEKKKLQEQRRQKKKKLQE 545
+ +QR R++ ++ +QR +Q+ +E+++ +EQ K +E+K+L+++RR+++ K +E
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK-RE 570
Query: 546 RKKWQGQMLQKEPEEEQQKQQLQEQ 570
+++ + Q+L++E E QQ+ + +++
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQE 595
Score = 55.8 bits (133), Expect = 1e-07
Identities = 27/103 (26%), Positives = 69/103 (66%), Gaps = 11/103 (10%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQL-----------REQRKVQKQKKMQEKKKLQEQKMQ 527
+QQ +++EQ + +QR RE++++L RE+ + ++++++ + ++ +E++ Q
Sbjct: 586 RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQ 645
Query: 528 EKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
+ ++ Q++RR+++ K +E ++ Q L++E EEE+++Q+L E+
Sbjct: 646 QLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688
Score = 55.8 bits (133), Expect = 1e-07
Identities = 49/213 (23%), Positives = 110/213 (51%), Gaps = 26/213 (12%)
Query: 378 KKLKEQLEERTWLLHDA-IQNQQNALELMMDH----------LQKQPNTLRHVVIPDLQS 426
+K++ Q +ER ++ + ++ Q+ +L + LQ++ H D +
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF 1645
Query: 427 SEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQE 486
E P+ ++++ Q++ H +D K L GE Q+ ++ ++E
Sbjct: 1646 LEEEPQLRRQEREQQLR----HDRDRK----FREEEQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 487 QHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQER 546
Q L+ Q+R+ R+ LQ+ ++ R+ + ++K +E+++L+++ QE+ + QE+ R+ ++ Q R
Sbjct: 1698 QQLRRQERE-RKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 547 KKWQGQMLQKEP------EEEQQKQQLQEQPLK 573
+ + Q L+++ EEEQ +Q+ +EQ L+
Sbjct: 1757 PEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789
Score = 55.5 bits (132), Expect = 2e-07
Identities = 24/90 (26%), Positives = 68/90 (75%), Gaps = 1/90 (1%)
Query: 482 LVQQEQHLKEQQRQLREQLQQLREQ-RKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKK 540
L ++E+ L+E++ Q + +LQ+ EQ RK+++Q+ +E+++ ++Q+ + +++ Q +R+Q++
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 541 KKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
++ +++++ + Q ++E +EE+++QQL+ +
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRRE 342
Score = 55.1 bits (131), Expect = 2e-07
Identities = 41/201 (20%), Positives = 107/201 (53%), Gaps = 10/201 (4%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E ++ +EQ E R Q ++ +L + +++ LR + + + +++
Sbjct: 316 EQQEERREQQERREQ------QEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 435 QKQHAGQVKRP--LPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQ 492
+++ Q++R L + ++ L L+ +L+ +QQL ++EQ L+ +
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL-RREQQLRRE 428
Query: 493 QRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQ 552
Q + R + Q+ ++R+ Q+ K+ QE+++ ++ +E ++ +++RR+++ K + ++ + +
Sbjct: 429 QEEERHE-QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 553 MLQKEPEEEQQKQQLQEQPLK 573
L+ E EE +++Q+ +EQ L+
Sbjct: 488 WLKLEEEERREQQERREQQLR 508
Score = 54.7 bits (130), Expect = 3e-07
Identities = 29/109 (26%), Positives = 71/109 (65%), Gaps = 4/109 (3%)
Query: 469 ELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKM-- 526
E Q+ + QQ +QE+ +EQQ + REQ ++ +Q + ++Q+ +E+++ +EQ++
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 527 --QEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
+E+++ Q+ RR+++++ +E++ + Q L++E + +++Q +EQ L+
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Score = 54.3 bits (129), Expect = 4e-07
Identities = 46/195 (23%), Positives = 104/195 (53%), Gaps = 17/195 (8%)
Query: 396 QNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCF 455
+ Q+ E + L+++ R LQ E ++ Q++ Q +R +D K
Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR-----RDQKWR 875
Query: 456 CGLSLSNSLKNTGELQEPCVAFN---QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQ 512
L + +P + +QQL+Q+E+ +E QR+ RE+ ++ ++R+ +++
Sbjct: 876 WQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE--EELQREEREKRRRQEQERQYREE 933
Query: 513 KKMQEKKKLQEQKMQEKKKLQEQRRQ--KKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
+++Q++++ ++ +EK++ QE+ RQ K KKLQ++++ Q+L +EPE+ +++Q +E+
Sbjct: 934 EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE---QLLGEEPEK--RRRQEREK 988
Query: 571 PLKHNVIVGNERVQI 585
+ + E Q+
Sbjct: 989 KYREEEELQQEEEQL 1003
Score = 53.5 bits (127), Expect = 7e-07
Identities = 37/117 (31%), Positives = 70/117 (59%), Gaps = 12/117 (10%)
Query: 469 ELQEPCVAFNQQQLVQQEQ----HLKEQQRQLREQLQQLREQR--KVQKQKKMQEKKKLQ 522
E + C ++ +EQ L E +R+ RE+ QQ R +R +V ++++ +E +K +
Sbjct: 191 EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE 250
Query: 523 EQKMQEKKKLQEQRRQKKKKLQER----KKWQGQMLQKEPEEEQQKQQ--LQEQPLK 573
+E++KLQE+ Q++++LQE +K + Q L++E +EE+Q+QQ +EQ L+
Sbjct: 251 TVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Score = 52.8 bits (125), Expect = 1e-06
Identities = 32/102 (31%), Positives = 65/102 (63%), Gaps = 9/102 (8%)
Query: 480 QQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQK-MQEKKKLQEQRRQ 538
Q+ +Q+ H +E+ R+ E+ QQLR Q + +K ++ + + + E+K ++E+++L Q+RQ
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530
Query: 539 KK---KKLQERKKWQGQMLQKE-----PEEEQQKQQLQEQPL 572
+K ++ Q R++ +GQ +++ EEEQ +Q+ +EQ L
Sbjct: 1531 RKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
Score = 52.4 bits (124), Expect = 2e-06
Identities = 44/203 (21%), Positives = 103/203 (50%), Gaps = 16/203 (7%)
Query: 370 ISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEA 429
+ +E +L +K +E+ E+ + + ++ E L+++ R + Q E
Sbjct: 300 LRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEER 359
Query: 430 VPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHL 489
++QQ + + +R L L+ +L+ +QQL +++Q
Sbjct: 360 --REQQLRREQEEERREQQ---------LRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Query: 490 KEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKW 549
+EQQ + +QL++ ++ R+ Q++++ ++K + QE++ Q K+ QE+RR K+ +E ++
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHE-QERREQRLKREQEERRDWLKREEETERH 467
Query: 550 Q----GQMLQKEPEEEQQKQQLQ 568
+ Q L+++ EEE++++ L+
Sbjct: 468 EQERRKQQLKRDQEEERRERWLK 490
Score = 52.4 bits (124), Expect = 2e-06
Identities = 57/213 (26%), Positives = 103/213 (48%), Gaps = 33/213 (15%)
Query: 372 QELELMKKLKEQLE-ERTWLLHDAIQNQQNALELMM---DHLQKQPNTLRHVVIPDLQSS 427
QELE + +E+L+ E LL + + ++ E + LQ+Q R+ D +S
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRD-EDQRSD 1222
Query: 428 EAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQ 487
+ +K++A +D K +C + + + Q +Q Q Q
Sbjct: 1223 LKWQWEPEKENA---------VRDNKVYCKGRENEQFRQLEDSQ-----LRDRQSQQDLQ 1268
Query: 488 HLK-EQQRQLREQLQQLREQR------KVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKK 540
HL EQQ + REQ ++ +QR + Q +++ Q++ K +++K QE+K+L + R++K
Sbjct: 1269 HLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEK 1328
Query: 541 KKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
++ QE + K EEEQ Q+ +EQPL+
Sbjct: 1329 RRRQETDR-------KFREEEQLLQEREEQPLR 1354
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/120 (29%), Positives = 72/120 (60%), Gaps = 28/120 (23%)
Query: 479 QQQLVQQEQHLKEQQRQLRE---QLQQLREQRKVQKQKKMQEKKKLQE--QKMQEKKKLQ 533
+Q+ + +E+ ++++RQ RE +LQ L E+ ++Q++++ Q+ ++ ++ Q+ QE+++ Q
Sbjct: 807 EQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQ 866
Query: 534 EQRRQKKKK-------------------LQERKKWQGQMLQKEPE----EEQQKQQLQEQ 570
EQRR +K + LQE+ + + Q+LQ+E E EE++K++ QEQ
Sbjct: 867 EQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926
Score = 51.2 bits (121), Expect = 4e-06
Identities = 60/268 (22%), Positives = 124/268 (46%), Gaps = 22/268 (8%)
Query: 380 LKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHA 439
L+EQL + LL + + Q E Q+Q R LQ E +++++
Sbjct: 895 LQEQLRKEQQLLQEEEEELQRE-EREKRRRQEQERQYREE--EQLQQEEEQLLREEREKR 951
Query: 440 GQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQL-RE 498
+ +R + KD K + GE E +++ ++E+ L++++ QL RE
Sbjct: 952 RRQERERQYRKDKKL-----QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE 1006
Query: 499 QLQQLREQ---RKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQ 555
+ ++ R Q R+ +K+ ++Q++++ ++ +EK++LQE+ RQ ++ +E + + + L
Sbjct: 1007 EREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE--EEELQQEEEQLL 1064
Query: 556 KEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNP----RDVSVPLCNHPVRFLQAQPIV 611
E E +++Q+L+ Q K + E Q+ + P R C Q + +
Sbjct: 1065 GEERETRRRQELERQYRKEEEL-QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Query: 612 ---PVQRAAEQQPSGFYQDENCGQQEDE 636
++ Q+ Y++E QQE+E
Sbjct: 1124 LREEREKRRRQELERQYREEEEVQQEEE 1151
Score = 51.2 bits (121), Expect = 4e-06
Identities = 29/91 (31%), Positives = 59/91 (64%), Gaps = 6/91 (6%)
Query: 479 QQQLVQQEQHLK----EQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQE 534
+QQL Q++ K E+Q QL EQ Q+LR++R +Q + +E+ QE+ +E+++L +
Sbjct: 1809 EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER--DRQYRAEEQFATQEKSRREEQELWQ 1866
Query: 535 QRRQKKKKLQERKKWQGQMLQKEPEEEQQKQ 565
+ QK+++ +ERK + + +++ EE++ +Q
Sbjct: 1867 EEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
Score = 50.8 bits (120), Expect = 5e-06
Identities = 41/209 (19%), Positives = 110/209 (52%), Gaps = 21/209 (10%)
Query: 368 DIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSS 427
++ +E +L+++ +E+ + W + +++ L+ + L ++ R + + Q
Sbjct: 995 ELQQEEEQLLREEREKRRRQEW---ERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 428 EAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQE- 486
E +Q+++ +R ++ L + ELQ+ ++QL+++E
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQE--------LERQYRKEEELQQ-----EEEQLLREEP 1098
Query: 487 --QHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQ 544
+ +E++RQ RE+ + +E+ ++ ++++ EK++ QE + Q +++ + Q+ +++ +
Sbjct: 1099 EKRRRQERERQCREEEELQQEEEQLLREER--EKRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 545 ERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
E +K + Q L+++ EE++ QQ +EQ L+
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLR 1185
Score = 50.4 bits (119), Expect = 6e-06
Identities = 35/161 (21%), Positives = 88/161 (54%), Gaps = 12/161 (7%)
Query: 480 QQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQK 539
++ +++EQ L+ Q+R + + Q+LR Q ++K ++E+++L Q+ Q K +EQ+ ++
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQELRSQE--PERKFLEEEQQLHRQQRQRKFLQEEQQLRR 1542
Query: 540 KKKLQERKKWQGQMLQKEPE--EEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPL 597
+++ Q+R++ + + ++E + +E+++QQL Q + ++V+ + ++
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVR---RQEQERKFME 1599
Query: 598 CNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQ 638
+R + Q Q+ +++ F +DE Q+ +E Q
Sbjct: 1600 DEQQLRRQEGQ-----QQLRQERDRKFREDEQLLQEREEQQ 1635
Score = 50.1 bits (118), Expect = 8e-06
Identities = 47/210 (22%), Positives = 107/210 (50%), Gaps = 18/210 (8%)
Query: 370 ISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIP--DLQSS 427
+ Q L ++L+ + EER L + ++ E L+++ R ++ + +
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587
Query: 428 EAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQ 487
+ + ++Q+++ ++KR ++V+ L + + +EP QQ L +EQ
Sbjct: 588 QRLKREQEERLEQRLKR-----EEVE---RLEQEERREQRLKREEPEEERRQQLLKSEEQ 639
Query: 488 HLKEQQRQLREQLQQLREQ---RKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQ 544
+ QQ+ REQ Q+ REQ R+ ++++ Q K+ E++ +E++ +E++ Q +++++
Sbjct: 640 EERRQQQLRREQ-QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK 698
Query: 545 ER-KKWQGQMLQKEPEEEQQKQQLQEQPLK 573
R KWQ Q+ E E + ++ ++ +P K
Sbjct: 699 SRIPKWQWQL---ESEADARQSKVYSRPRK 725
Score = 50.1 bits (118), Expect = 8e-06
Identities = 29/108 (26%), Positives = 70/108 (64%), Gaps = 16/108 (14%)
Query: 479 QQQLVQQEQH---LKEQQRQLREQLQQLREQ---RKVQKQKKMQEKKKLQ-------EQK 525
Q+QL +QE++ L+E+Q + + QQLR Q RK +++++++++++ Q ++K
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRK 1796
Query: 526 MQEKKKLQEQRRQKKKKLQERK---KWQGQMLQKEPEEEQQKQQLQEQ 570
+E+++L+++R +++ + Q+R +W+ + LQ E +E++ +Q+ Q
Sbjct: 1797 FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/233 (21%), Positives = 117/233 (50%), Gaps = 24/233 (10%)
Query: 424 LQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQL- 482
LQ E P ++Q++ + L H + + F L + + +E +QQL
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKF----LEEEQRLRRQERERKFLKEEQQLR 1400
Query: 483 -VQQEQHLKEQQ-RQLREQLQQLREQRKVQKQKKMQEKKKLQEQK---MQEKKKLQEQR- 536
++EQ L++ + R+ RE+ QQL Q + +K ++ +++ + QE++ ++E+++L+++R
Sbjct: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERH 1460
Query: 537 ---RQKKKKLQERKKWQGQMLQKE----PEEEQQKQQLQEQPLKHNVIVGNERVQICLQN 589
R++++ LQER++ Q +++ EE+Q ++Q +++ + + E + L+
Sbjct: 1461 RKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 590 PRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSG----FYQDENCGQQEDESQ 638
+ + +FLQ + + Q +Q+ F ++E Q+ +E Q
Sbjct: 1521 EQQLHRQ--QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Score = 48.9 bits (115), Expect = 2e-05
Identities = 29/118 (24%), Positives = 67/118 (56%), Gaps = 23/118 (19%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQR---KVQKQKKMQEKKKLQEQKMQEKKKLQEQ 535
+QQL++ E+ + +Q+QLR + Q+ REQR + ++++ Q K+ E++ +E++ +E+
Sbjct: 630 RQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE 689
Query: 536 RRQKKKKLQER-KKWQGQML-------------------QKEPEEEQQKQQLQEQPLK 573
+ Q +++++ R KWQ Q+ Q+ +E+++K++ +E L+
Sbjct: 690 QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQ 747
Score = 48.9 bits (115), Expect = 2e-05
Identities = 37/110 (33%), Positives = 62/110 (56%), Gaps = 20/110 (18%)
Query: 479 QQQLVQQEQHLK----EQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQE 534
+QQL QE K EQ RQ RE+ QQLR Q++ K + +E+ +L+EQ+ + +++
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREE-QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDR 1843
Query: 535 QRR-------QKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVI 577
Q R Q+K + +E++ WQ EEEQ+++Q +E+ L+ I
Sbjct: 1844 QYRAEEQFATQEKSRREEQELWQ--------EEEQKRRQERERKLREEHI 1885
Score = 48.5 bits (114), Expect = 2e-05
Identities = 43/171 (25%), Positives = 90/171 (52%), Gaps = 12/171 (7%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ 538
++Q ++E+ +E+++ LRE+ ++ R Q + +++ +E+++LQ+++ Q ++ QE+RRQ
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQ---ELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 539 -KKKKLQERKKWQGQMLQKEPEEEQQKQQL--QEQPLKHNVIVGNERVQICLQNPRDVSV 595
++++ +E ++ Q Q ++ +E Q+ L Q +P K N + N+ C +
Sbjct: 1194 ERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK--VYCKGRENEQFR 1251
Query: 596 PLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQ 646
L + +R Q+Q + EQQ Q+ QQ D +PE Q
Sbjct: 1252 QLEDSQLRDRQSQQDLQ-HLLGEQQERDREQERRRWQQRDR---HFPEEEQ 1298
Score = 48.1 bits (113), Expect = 3e-05
Identities = 39/183 (21%), Positives = 92/183 (50%), Gaps = 23/183 (12%)
Query: 479 QQQLVQQEQHLKEQQRQLR----EQLQQLREQRKVQKQKKMQ------------EKKKLQ 522
+++ +Q+EQ L+ Q+ + + EQL+Q EQ ++++Q++ + E+++L+
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 523 EQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPE--EEQQKQQLQEQPLKHNVIVGN 580
Q+ K + +EQ RQ++++ Q R + + ++E + +E+++QQL+ Q
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825
Query: 581 ERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSF 640
E++Q+ Q R L R +A+ Q + ++ +Q+E ++++ +
Sbjct: 1826 EQLQLEEQEQR-----LRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKL 1880
Query: 641 YPE 643
E
Sbjct: 1881 REE 1883
Score = 47.8 bits (112), Expect = 4e-05
Identities = 42/207 (20%), Positives = 106/207 (51%), Gaps = 13/207 (6%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNAL---ELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
E +K + Q ER + D +Q ++ L E LQ++ R + + +
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHL-- 489
++++ + +++R ++++ L + + +++L Q+E+ L
Sbjct: 1066 EERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLR 1125
Query: 490 KEQQRQLREQLQ-QLREQRKVQKQKKM-----QEKKKLQEQKMQ--EKKKLQEQRRQKKK 541
+E++++ R++L+ Q RE+ +VQ++++ EK++ QE + Q E+++LQ++ Q +
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLR 1185
Query: 542 KLQERKKWQGQMLQKEPEEEQQKQQLQ 568
+ QE+++ + + +E EE Q++++ Q
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQ 1212
Score = 47.0 bits (110), Expect = 7e-05
Identities = 25/96 (26%), Positives = 62/96 (64%), Gaps = 1/96 (1%)
Query: 479 QQQLVQQEQ-HLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRR 537
++QL ++EQ K + R+ +E+ Q LRE+R+ +++++ ++K +E+++ ++++ Q RR
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 538 QKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
Q++ + ++ + Q ++ EE+Q+ + QE+ K
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/166 (19%), Positives = 90/166 (54%), Gaps = 15/166 (9%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQK----KMQEKKKLQEQKMQEKKKLQE 534
Q++L Q+++ ++++ + Q Q RE+R+ ++++ K E ++ +++ +++L E
Sbjct: 158 QERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLE 217
Query: 535 QRRQ-KKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNP-RD 592
RR+ +++K Q+R++ Q ++ Q+E E+E +K++ ++ E ++ + P R
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE---------TVLRKEEEKLQEEEPQRQ 268
Query: 593 VSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQ 638
+ +R L+ Q + ++ EQQ +++ ++++E +
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Score = 45.8 bits (107), Expect = 1e-04
Identities = 22/95 (23%), Positives = 66/95 (69%), Gaps = 3/95 (3%)
Query: 479 QQQLVQQEQHL--KEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK-KLQEQ 535
QQQ +++ + +E++++ R++ LR++ + ++++ Q +++LQE++ Q +K + QE
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 536 RRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
RR+++++ Q++++ + + + +EE++++Q +E+
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Score = 45.8 bits (107), Expect = 1e-04
Identities = 36/213 (16%), Positives = 106/213 (49%), Gaps = 14/213 (6%)
Query: 372 QELELMKKLKEQLEERTWLLHDAI-----QNQQNALELMMDHLQKQPNTLRHVVIPDLQS 426
Q E ++ ++ EE+ W + + + Q LQ++ LR + +L+
Sbjct: 229 QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR 288
Query: 427 SEAVPKKQQKQ--HAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQ 484
++QQ++ Q++R + + + E +E + Q++ +
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 485 QEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKL- 543
Q+ ++++ + +QL++ +E+ + ++Q + +++ + ++Q +E++ +EQ+ +++++L
Sbjct: 349 QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Query: 544 ------QERKKWQGQMLQKEPEEEQQKQQLQEQ 570
+E++ + Q L++E EEE+ +Q+ +++
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQE 441
Score = 45.8 bits (107), Expect = 1e-04
Identities = 25/96 (26%), Positives = 62/96 (64%), Gaps = 8/96 (8%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQE---- 534
+Q+L + ++++RQLR + +Q REQR + ++++ +++++ + ++ +E + L+E
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
Query: 535 QRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
QRR++ ++LQE + LQ++ E + ++Q ++Q
Sbjct: 841 QRRERAQQLQEEE----DGLQEDQERRRSQEQRRDQ 872
Score = 45.4 bits (106), Expect = 2e-04
Identities = 27/102 (26%), Positives = 61/102 (59%), Gaps = 2/102 (1%)
Query: 484 QQEQHLKEQQRQLREQLQQLREQRK-VQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKK 542
++E L+ Q+ + + QQ EQR+ Q + +EK + Q++ + L+EQR +++ +
Sbjct: 741 RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQR-ERQLR 799
Query: 543 LQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQ 584
+ER++ + + L +E E+EQ+++Q +E+ + + E++Q
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ 841
Score = 45.1 bits (105), Expect = 3e-04
Identities = 40/205 (19%), Positives = 106/205 (51%), Gaps = 26/205 (12%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
+E +L ++ +E+ E+ ++ +Q +L + ++ LR L+ + +
Sbjct: 360 REQQLRREQEEERREQQLRREQQLRREQ---QLRREQQLRREQQLRRE--QQLRREQQLR 414
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQ----LVQQEQ 487
++QQ + Q++R + + K+ E +E + Q++ L ++E+
Sbjct: 415 REQQLRREQQLRREQEEER-----------HEQKHEQERREQRLKREQEERRDWLKREEE 463
Query: 488 HLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERK 547
+ +Q + ++QL++ +E+ + ++ K++E+++ ++Q+ +E Q+ RR+++++ ++R
Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE----QQLRREQEERREQRL 519
Query: 548 KWQ--GQMLQKEPEEEQQKQQLQEQ 570
K Q + LQ+ EQQ ++ QE+
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEE 544
Score = 45.1 bits (105), Expect = 3e-04
Identities = 42/213 (19%), Positives = 99/213 (46%), Gaps = 35/213 (16%)
Query: 370 ISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEA 429
+ QE + +EQ E R LL + +Q L+ + +Q L+ E
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR----------LKREEV 607
Query: 430 VPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHL 489
+Q+++ ++KR P + L + E +E QQQL +++Q
Sbjct: 608 ERLEQEERREQRLKREEPEEER---------RQQLLKSEEQEER----RQQQLRREQQER 654
Query: 490 KEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQ------------EQRR 537
+EQ+ + E+ ++L ++ K + +++ +E++ +E++ Q +++++ E
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 538 QKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
++ K +K +GQ ++E EE++++++ + Q
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQ 747
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/219 (22%), Positives = 98/219 (44%), Gaps = 34/219 (15%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
+E L ++LK + EE A + Q+ A E + + K L + P
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRP 723
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHL-- 489
+KQ+ Q Q + ++ + + QE A QQQ +Q +
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESEL--------------QWQEEERAHRQQQEEEQRRDFTW 769
Query: 490 -------KEQQRQLREQLQQLREQRKVQ---KQKKMQEKKKLQEQKMQEKKKLQEQRRQK 539
E+ RQ LREQR+ Q ++++ +E++ L E++ +E+++ Q + R+K
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
Query: 540 KKKLQE-----RKKWQGQMLQKEP---EEEQQKQQLQEQ 570
+ + E +++ + Q LQ+E +E+Q++++ QEQ
Sbjct: 830 ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/86 (26%), Positives = 59/86 (68%), Gaps = 10/86 (11%)
Query: 484 QQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKL 543
+++ L+EQ+++LR Q+ Q + ++Q QEK + +EQ++ ++++ Q++R+++++KL
Sbjct: 1825 EEQLQLEEQEQRLR---QERDRQYRAEEQFATQEKSRREEQELWQEEE-QKRRQERERKL 1880
Query: 544 QERKKWQGQMLQKEPEEEQQKQQLQE 569
+E + ++++ +EEQ+ +Q+ E
Sbjct: 1881 RE------EHIRRQQKEEQRHRQVGE 1900
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/104 (25%), Positives = 61/104 (58%), Gaps = 4/104 (3%)
Query: 467 TGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQ-RKVQKQKKMQEKKKLQEQK 525
TG +E + ++ + Q++ +E QR+ + +QL E+ + ++QK+ +++++L E +
Sbjct: 93 TGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE 152
Query: 526 MQEKKKLQEQRRQKKKKLQERKKW-QGQMLQKEPEEEQQKQQLQ 568
Q +K QE+ Q+ ++ ++ + W Q Q Q+ E +++QLQ
Sbjct: 153 EQSEK--QERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQ 194
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/97 (30%), Positives = 62/97 (63%), Gaps = 8/97 (8%)
Query: 479 QQQLVQQ--EQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQR 536
++QL+Q+ EQ L+ Q+R + + ++LR Q Q +K ++E+++L+ Q+ +E+K L+E
Sbjct: 1341 EEQLLQEREEQPLRRQERDRKFREEELRHQE--QGRKFLEEEQRLRRQE-RERKFLKE-- 1395
Query: 537 RQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
+++ + QER++ Q ++ EE+Q+ QE+ K
Sbjct: 1396 -EQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK 1431
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/99 (30%), Positives = 62/99 (62%), Gaps = 16/99 (16%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQ---RQLREQ--LQQLREQRKVQKQKKMQEKKKLQEQK 525
+E V ++QL+++E + +Q RQ RE+ LQQ EQ ++Q+K ++++ E++
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER---ERQ 1198
Query: 526 MQEKKKLQEQRRQKKKKLQERK---KWQGQMLQKEPEEE 561
+E+++LQ Q+R+++ + ++++ KWQ EPE+E
Sbjct: 1199 YREEEELQRQKRKQRYRDEDQRSDLKWQW-----EPEKE 1232
Score = 42.0 bits (97), Expect = 0.002
Identities = 23/113 (20%), Positives = 64/113 (56%), Gaps = 4/113 (3%)
Query: 480 QQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQK 539
+QL + ++ Q+ L+ L + +E+ + Q++++ Q++ + ++ Q +++ Q++ +++
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310
Query: 540 KKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRD 592
+K QE K Q+L++E EE++++Q+ + + ++ Q + RD
Sbjct: 1311 DRKSQEEK----QLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
Score = 39.7 bits (91), Expect = 0.011
Identities = 24/110 (21%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Query: 478 NQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRR 537
+Q++ +++ L+E+ Q R Q +Q +E+ + +++ +++++L+++ Q + + ++R
Sbjct: 118 DQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQR 177
Query: 538 QKKKKLQERKKWQGQMLQ---KEPEEEQQKQQLQEQPLKHNVIVGNERVQ 584
Q+ ++ +ER+ + Q+ E EE ++QL+ + L G E Q
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ 227
Score = 38.9 bits (89), Expect = 0.018
Identities = 24/88 (27%), Positives = 53/88 (60%), Gaps = 11/88 (12%)
Query: 479 QQQLVQQEQHLKEQ-------QRQLREQLQQLREQRKV---QKQKKMQEK-KKLQEQKMQ 527
Q QL +QEQ L+++ + Q Q + RE++++ ++QK+ QE+ +KL+E+ ++
Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886
Query: 528 EKKKLQEQRRQKKKKLQERKKWQGQMLQ 555
++K +++ RQ + + K G++L+
Sbjct: 1887 RQQKEEQRHRQVGEIKSQEGKGHGRLLE 1914
Score = 36.2 bits (82), Expect = 0.12
Identities = 39/207 (18%), Positives = 99/207 (47%), Gaps = 11/207 (5%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
++ L ++ +E+LE+R L + ++ + +++P R + L+S E
Sbjct: 586 RQQRLKREQEERLEQR--LKREEVERLEQEERREQRLKREEPEEERRQQL--LKSEEQEE 641
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQ--EQHL 489
++QQ+ Q +R K + L ++ E +E +A +Q+ ++ + +
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 490 KEQQRQLREQLQQLREQ-----RKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQ 544
+ Q QL + + + RK + Q++ QE+++ + ++ E + +E+R ++++ +
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Query: 545 ERKKWQGQMLQKEPEEEQQKQQLQEQP 571
E+++ Q E + E+ +Q+L +P
Sbjct: 762 EQRRDFTWQWQAEEKSERGRQRLSARP 788
Score = 33.1 bits (74), Expect = 1.0
Identities = 26/153 (16%), Positives = 71/153 (46%), Gaps = 49/153 (32%)
Query: 479 QQQLVQQEQHL--KEQQRQLREQLQQLREQRKVQKQKKMQ-------------------- 516
+++L Q+E+ L +EQ+++ +E+ +Q RE+ ++Q+QK+ Q
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232
Query: 517 ----------------EKKKLQEQKMQEKKKLQE-----------QRRQKKKKLQERKKW 549
+ ++L++ ++++++ Q+ R Q++++ Q+R +
Sbjct: 1233 NAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRH 1292
Query: 550 QGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNER 582
+ Q E EE+++ ++ + + ++ ER
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREER 1325
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 67.0 bits (162), Expect = 6e-11
Identities = 32/106 (30%), Positives = 74/106 (69%)
Query: 480 QQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQK 539
Q L+QQ+Q + QQ+QL+E ++ +EQ +Q ++ Q++++ Q+Q+ Q++++ Q+Q++Q+
Sbjct: 27 QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 86
Query: 540 KKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQI 585
+++ Q++++ Q Q K+ +E+QQ+QQ Q+Q ++ + +Q+
Sbjct: 87 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQM 132
Score = 60.5 bits (145), Expect = 6e-09
Identities = 30/95 (31%), Positives = 69/95 (72%), Gaps = 5/95 (5%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQ-QLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRR 537
QQ ++ Q+Q L+E ++ +EQL QL +Q++ Q+Q++ Q+ Q+Q+ Q++++ Q+Q++
Sbjct: 33 QQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQ----QQQQQQQQQQQQQQQQ 88
Query: 538 QKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPL 572
Q++++ Q++++ G+ +++ +++QQ+QQL Q L
Sbjct: 89 QQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123
Score = 59.7 bits (143), Expect = 1e-08
Identities = 30/93 (32%), Positives = 65/93 (69%), Gaps = 1/93 (1%)
Query: 481 QLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKK 540
QL+QQ+Q ++QQ+Q ++Q QQ ++Q++ Q+Q++ Q++++ Q+ ++ K+ Q+Q++Q++
Sbjct: 57 QLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 116
Query: 541 KKLQERKKWQGQMLQKEPEEEQQK-QQLQEQPL 572
+ ++ +Q Q+LQ + ++QQ LQ Q L
Sbjct: 117 QLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGL 149
Score = 58.5 bits (140), Expect = 2e-08
Identities = 40/131 (30%), Positives = 78/131 (59%), Gaps = 14/131 (10%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQL--QQLREQRKVQKQKKMQEKKKLQEQKMQE 528
Q+ V QQQL ++ K+QQ QL QL QQ ++Q++ Q+Q++ Q++++ Q+Q+ Q+
Sbjct: 32 QQQAVMLQQQQL---QEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 88
Query: 529 KKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQ---QKQQLQEQPLKHNVIVGNERVQI 585
+++ Q+Q++Q+ Q +++ Q Q Q++ +Q Q+Q LQ Q L+ ++ +
Sbjct: 89 QQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQ------QQQHLL 142
Query: 586 CLQNPRDVSVP 596
LQ +S+P
Sbjct: 143 SLQRQGLISIP 153
Score = 56.6 bits (135), Expect = 8e-08
Identities = 37/115 (32%), Positives = 73/115 (63%), Gaps = 12/115 (10%)
Query: 479 QQQLV--QQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQR 536
QQQ++ QQ Q L +QQ+ + Q QQL+E K KQ++ + LQ+Q+ Q++++ Q+Q+
Sbjct: 17 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYK--KQQEQLHLQLLQQQQQQQQQQQQQQQ 74
Query: 537 RQKKKKLQERKKWQGQMLQKEPEE--------EQQKQQLQEQPLKHNVIVGNERV 583
+Q++++ Q++++ Q Q Q++ ++ EQQ+QQ Q+Q L +V +++
Sbjct: 75 QQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 129
Score = 54.7 bits (130), Expect = 3e-07
Identities = 32/94 (34%), Positives = 63/94 (67%), Gaps = 4/94 (4%)
Query: 484 QQEQHLKEQQRQLREQLQQLREQRK---VQKQKKMQEKKKLQEQ-KMQEKKKLQEQRRQK 539
QQ Q + +QQ +QLQ L +Q++ +Q+Q+ + KK QEQ +Q ++ Q+Q++Q+
Sbjct: 10 QQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69
Query: 540 KKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
+++ Q++++ Q Q Q++ +++QQ+QQ Q+ P K
Sbjct: 70 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK 103
Score = 53.1 bits (126), Expect = 9e-07
Identities = 34/113 (30%), Positives = 67/113 (59%), Gaps = 5/113 (4%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQ---LREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQ 535
Q Q + Q+Q L QQ Q Q QQ L++Q+ + KK QE+ LQ +Q++++ Q+Q
Sbjct: 11 QMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQ--LLQQQQQQQQQ 68
Query: 536 RRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQ 588
++Q++++ Q++++ Q Q Q++ +++QQ+QQ + K ++ Q+ Q
Sbjct: 69 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQ 121
Score = 45.8 bits (107), Expect = 1e-04
Identities = 25/81 (30%), Positives = 54/81 (66%), Gaps = 3/81 (3%)
Query: 470 LQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQ---KQKKMQEKKKLQEQKM 526
LQ+ QQQ QQ+Q ++QQ+Q ++Q QQ ++Q++ Q KQ K Q++++ Q+Q++
Sbjct: 59 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQL 118
Query: 527 QEKKKLQEQRRQKKKKLQERK 547
++ + +Q+ + ++LQ+++
Sbjct: 119 AAQQLVFQQQLLQMQQLQQQQ 139
Score = 37.7 bits (86), Expect = 0.041
Identities = 37/182 (20%), Positives = 78/182 (42%), Gaps = 44/182 (24%)
Query: 358 PLQPSSPVAYDIIS-QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTL 416
P Q + ++S Q+L+ + + ++ + + L + + QQ L L + Q+Q
Sbjct: 9 PQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ-- 66
Query: 417 RHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVA 476
Q + ++QQ+Q Q ++
Sbjct: 67 --------QQQQQQQQQQQQQQQQQQQQ-------------------------------- 86
Query: 477 FNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQR 536
QQQ QQ+Q + +Q +EQ QQ ++Q+++ Q+ + +++ LQ Q++Q+++ L +
Sbjct: 87 -QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ 145
Query: 537 RQ 538
RQ
Sbjct: 146 RQ 147
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.0 bits (162), Expect = 6e-11
Identities = 43/193 (22%), Positives = 106/193 (54%), Gaps = 23/193 (11%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K+++Q EE+ W + + +Q+ + + + +Q +R + E + ++
Sbjct: 547 EQEEKIRKQ-EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI--RE 603
Query: 435 QKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR 494
Q++ + + + ++ C QE + ++++ +QE+ ++EQ++
Sbjct: 604 QEEMTQEQEEKMGEQEEKMCE---------------QEEKMQEQEEKMRRQEEKIREQEK 648
Query: 495 QLREQLQQLREQRKVQKQKKMQEKKKLQEQKM-QEKKKLQEQRRQKKKKLQERKKWQGQM 553
++REQ +++REQ ++ +++ +EK QE+KM ++++K+QEQ ++K + QE K W+ ++
Sbjct: 649 KIREQEEKIREQEEMMQEQ--EEKMWEQEEKMCEQEEKMQEQ--EEKMRRQEEKMWEQEV 704
Query: 554 LQKEPEEEQQKQQ 566
++ EE+ Q+ Q
Sbjct: 705 RLRQQEEKMQEHQ 717
Score = 64.3 bits (155), Expect = 4e-10
Identities = 44/217 (20%), Positives = 112/217 (51%), Gaps = 21/217 (9%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
+E EL +L +Q EE+ W + IQ + ++ + +++Q +R + E +
Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 406
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
+K++K + + K+ K QE + ++++ + E+ + E
Sbjct: 407 EKEEKMRR---QEEMMWEKEEKM--------------RRQEEMMWEKEEKIRELEEKMHE 449
Query: 492 QQRQLREQLQQLREQRKVQKQKKMQEKKKL---QEQKMQEKKKLQEQRRQKKKKLQERKK 548
Q++ +REQ ++ +E+ K+++Q+K QE++ QE+K++E+++ ++ +K + +E+
Sbjct: 450 QEK-IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIH 508
Query: 549 WQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQI 585
Q ++ ++E +EQ++ QE+ ++ + ++ +I
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI 545
Score = 62.8 bits (151), Expect = 1e-09
Identities = 53/216 (24%), Positives = 117/216 (54%), Gaps = 27/216 (12%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K++EQ EE+ W + I Q+ E + Q+Q R ++ E + +++
Sbjct: 488 EQEEKIREQ-EEKMWRQEEKIHEQEKIRE--EEKRQEQEEMWRQE--EKIREQEEIWRQK 542
Query: 435 QKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR 494
+K H + K ++ K + + + QE V ++++ +QE+ ++EQ+
Sbjct: 543 EKIHEQEEKI---RKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599
Query: 495 QLREQLQQLREQRK---VQKQKKMQEKKKLQEQKMQEKKKLQEQR-RQKKKKLQERK--- 547
++REQ + +EQ + Q++K ++++K+QEQ +EK + QE++ R+++KK++E++
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ--EEKMRRQEEKIREQEKKIREQEEKI 657
Query: 548 KWQGQMLQKEPE----------EEQQKQQLQEQPLK 573
+ Q +M+Q++ E E+++K Q QE+ ++
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 693
Score = 60.5 bits (145), Expect = 6e-09
Identities = 54/219 (24%), Positives = 116/219 (52%), Gaps = 37/219 (16%)
Query: 373 ELEL-MKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
E++L +K+LK +LE LL Q L+ DHL K+ LQS A
Sbjct: 300 EIQLNVKELKRKLERAKLLL------PQQQLQAEADHLGKE-----------LQSVSA-- 340
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
K Q + ++ L ++ K + + + QE + ++++ +QE+ ++
Sbjct: 341 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 400
Query: 492 QQRQLREQLQQLREQRKV--QKQKKMQEKKKLQ----------EQKMQEKKKL--QEQRR 537
Q+ + E+ +++R Q ++ +K++KM+ ++++ E+KM E++K+ QE++R
Sbjct: 401 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 460
Query: 538 QKKKKLQERKKWQGQ---MLQKEPEEEQQKQQLQEQPLK 573
Q+++K++E++K Q Q M ++E + +Q+++++EQ K
Sbjct: 461 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Score = 56.6 bits (135), Expect = 8e-08
Identities = 43/198 (21%), Positives = 100/198 (50%), Gaps = 16/198 (8%)
Query: 370 ISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEA 429
I ++ ++ ++ K Q +E W + I+ Q+ + + +Q +R + E
Sbjct: 507 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR-QKEKIHEQEEKIR-------KQEEK 558
Query: 430 VPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHL 489
+ ++++K H + K ++ K + + QE + ++ +QE+ +
Sbjct: 559 MWRQEEKMHDQEEKI---REQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 490 KEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQE-KKKLQEQRRQKKKKLQERKK 548
EQ+ ++ EQ ++++EQ +K ++ +EK + QE+K++E ++K++EQ ++ QE K
Sbjct: 616 GEQEEKMCEQEEKMQEQE--EKMRRQEEKIREQEKKIREQEEKIREQEEMMQE--QEEKM 671
Query: 549 WQGQMLQKEPEEEQQKQQ 566
W+ + E EE+ Q+Q+
Sbjct: 672 WEQEEKMCEQEEKMQEQE 689
Score = 55.5 bits (132), Expect = 2e-07
Identities = 53/219 (24%), Positives = 112/219 (51%), Gaps = 36/219 (16%)
Query: 368 DIISQELELMKKLKEQLEERTWLLHDAIQ---NQQNALELMMDHLQKQPNTLRHVVIPDL 424
D +S EL E+L+E+ L + +Q ++++ ++L + L+++ + ++
Sbjct: 264 DALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLL---- 319
Query: 425 QSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQ--- 481
P++Q + A + + L S+S L+ E E NQQQ
Sbjct: 320 ------PQQQLQAEADHLGKELQ-----------SVSAKLQAQVEENELWNRLNQQQEEK 362
Query: 482 LVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKM---QEKKKLQEQ--- 535
+ +QE+ ++E + +++EQ +++REQ +K ++ +EK + QE+ M +EK + QE+
Sbjct: 363 MWRQEEKIQEWEEKIQEQEEKIREQE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 420
Query: 536 RRQKKKKLQERKKWQGQMLQKEPEEEQQKQQ-LQEQPLK 573
+++K + QE W+ + +E EE+ +Q+ ++EQ K
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 459
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 66.2 bits (160), Expect = 1e-10
Identities = 48/200 (24%), Positives = 108/200 (54%), Gaps = 11/200 (5%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
+E EL +L +Q EE+ W + IQ + ++ + +++Q +R + E +
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
+K++K + + K+ K + + QE + ++++ + E+ + E
Sbjct: 346 EKEEKMRR---QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 402
Query: 492 QQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKM-QEKKKLQEQRRQKKKKLQERKKWQ 550
Q++ +REQ ++ +E+ K+++Q+K QE QE KM ++++K++EQ ++K + QE+K W+
Sbjct: 403 QEK-IREQEEKRQEEEKIREQEKRQE----QEAKMWRQEEKIREQ--EEKIREQEKKMWR 455
Query: 551 GQMLQKEPEEEQQKQQLQEQ 570
+ E E+ +++++ QEQ
Sbjct: 456 QEEKIHEQEKIREEEKRQEQ 475
Score = 63.9 bits (154), Expect = 5e-10
Identities = 48/193 (24%), Positives = 102/193 (52%), Gaps = 26/193 (13%)
Query: 378 KKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQ 437
+K++EQ EE+ W + I+ Q+ + + + KQ +R + E + ++++K
Sbjct: 577 EKIREQ-EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Query: 438 HAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLR 497
+ K GE QE + ++++ +QE+ + Q+ ++R
Sbjct: 636 REQEEMTQEQEEK----------------MGE-QEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 498 EQLQQLREQ-RKVQKQKKM----QEKKKLQEQKM-QEKKKLQEQRRQKKKKLQERKKWQG 551
EQ +++REQ K+++Q++M +EK QE+KM ++++K+QEQ ++K + QE K W+
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ--EEKMRRQEEKMWEQ 736
Query: 552 QMLQKEPEEEQQK 564
++ ++ EE+ Q+
Sbjct: 737 EVRLRQQEEKMQE 749
Score = 63.5 bits (153), Expect = 7e-10
Identities = 59/281 (20%), Positives = 128/281 (45%), Gaps = 39/281 (13%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K++EQ E++ W + I Q+ E + Q+Q R + E + +++
Sbjct: 441 EQEEKIREQ-EKKMWRQEEKIHEQEKIRE--EEKRQEQEEMWRQE--EKIHEQEEIWRQK 495
Query: 435 QKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR 494
+K H + K K + QE + ++++ +QE+ + Q+
Sbjct: 496 EKMHEQEEKIRKQEEKVWR-----------------QEEKIREQEEKIREQEEKMWRQEE 538
Query: 495 QLREQLQQLREQRKVQKQKKMQEKKKLQEQ-----KMQEKKKLQEQR----------RQK 539
++REQ + RE+ K+ +Q+K+ E++K QEQ + +EK + QE++ +++
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE 598
Query: 540 KKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCN 599
K++ QE K W+ + +E EE+ Q+Q+ + + + + E Q + + +C
Sbjct: 599 KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658
Query: 600 HPVRFLQAQPIV--PVQRAAEQQPSGFYQDENCGQQEDESQ 638
+ + + + ++ EQ+ Q+E +QE+ Q
Sbjct: 659 QEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQ 699
Score = 60.1 bits (144), Expect = 8e-09
Identities = 49/229 (21%), Positives = 118/229 (51%), Gaps = 31/229 (13%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVI-----PDLQSSEA 429
E +K+++Q EE+ W + I+ Q+ + + + +Q +R + E
Sbjct: 500 EQEEKIRKQ-EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEK 558
Query: 430 V---PKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQE 486
+ K+Q+++ + ++ K + + + QE + ++++ +QE
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 487 QHLKEQQRQLREQLQQLREQRKV-----QKQKKMQEKKKLQEQKMQEKK----KLQEQRR 537
+ ++EQ+ ++REQ +++REQ ++ +K + +EK QE+KMQE++ + +E+ R
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 538 QKKKKLQERK---KWQGQMLQKEPE----------EEQQKQQLQEQPLK 573
+++KK++E++ + Q +M+Q++ E E+++K Q QE+ ++
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727
Score = 57.0 bits (136), Expect = 6e-08
Identities = 46/207 (22%), Positives = 105/207 (50%), Gaps = 39/207 (18%)
Query: 373 ELEL-MKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
E++L +K+LK +LE LL Q L+ DHL K+ ++ + ++ +E
Sbjct: 239 EIQLNVKELKRKLERAKLLL------PQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 292
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
+ Q+Q + QE + ++++ +QE+ ++E
Sbjct: 293 RLNQQQEEKMWR---------------------------QEEKIQEWEEKIQEQEEKIRE 325
Query: 492 QQRQLREQLQQLREQRKV--QKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKL--QERK 547
Q+ ++REQ +++R Q ++ +K++KM+ ++++ +K ++ ++ +E +K++K+ QE
Sbjct: 326 QEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385
Query: 548 KWQGQMLQKEPEEEQQKQQ-LQEQPLK 573
W+ + +E EE+ +Q+ ++EQ K
Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEK 412
Score = 57.0 bits (136), Expect = 6e-08
Identities = 27/103 (26%), Positives = 70/103 (67%), Gaps = 7/103 (6%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL--QEQKMQE 528
QE + ++++ +QE+ ++EQ++++ Q +++ EQ K+++++K QE++++ QE+K+ E
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHE 487
Query: 529 KKKLQEQR-----RQKKKKLQERKKWQGQMLQKEPEEEQQKQQ 566
++++ Q+ +++K + QE K W+ + +E EE+ ++Q+
Sbjct: 488 QEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Score = 37.7 bits (86), Expect = 0.041
Identities = 22/96 (22%), Positives = 52/96 (54%), Gaps = 12/96 (12%)
Query: 486 EQHLKEQQRQLREQLQQLREQ------------RKVQKQKKMQEKKKLQEQKMQEKKKLQ 533
++ LKE+ +L+E+LQ + + RK+++ K + +++LQ + K+LQ
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 534 EQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQE 569
+ + +++E + W Q+E + +Q++++QE
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 65.9 bits (159), Expect = 1e-10
Identities = 46/232 (19%), Positives = 120/232 (51%), Gaps = 35/232 (15%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
+E EL +L +Q EE+ W + IQ ++ ++ + +++Q +R + E +
Sbjct: 274 EENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMR-------RQEEMMW 326
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
+K++K + + K+ K L + +++E Q++ Q+E+ ++E
Sbjct: 327 EKEEKMRR---QEEMMWEKEEKI---RELEEKMHEQEKIRE------QEEKRQEEEKIRE 374
Query: 492 QQRQLREQLQQLREQRKVQKQ-----------KKMQEKKKLQEQKMQEKKKLQEQRRQKK 540
Q+++ ++ + R++ K+++Q ++ +EK QE+KM E+++ +++ +K
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKM 434
Query: 541 KKLQERKKWQGQMLQKEPEE-EQQKQQLQEQPLKHNVIVGNERVQICLQNPR 591
++ +E+ + Q + ++++ E+ +Q++ +QEQ K +G + ++C Q +
Sbjct: 435 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK----MGEQEGKMCEQEAK 482
Score = 63.5 bits (153), Expect = 7e-10
Identities = 39/197 (19%), Positives = 105/197 (53%), Gaps = 29/197 (14%)
Query: 370 ISQELELMKKLKEQL---EERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQS 426
I ++ E+M++ +E++ EE+ W + +Q Q+ + + +++Q +R +
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Query: 427 SEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQE 486
E + ++++K G + ++QE ++++ +QE
Sbjct: 459 EEMMQEQEEKM-------------------GEQEGKMCEQEAKMQE-----QEEKMRRQE 494
Query: 487 QHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQER 546
+ ++EQ++++REQ +++REQ ++ +++ +EK QE+KM E+++ +++ +K ++ +E+
Sbjct: 495 EKIREQEKKIREQEEKIREQEEMMQEQ--EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 547 KKWQGQMLQKEPEEEQQ 563
+ Q L+++ E+ Q+
Sbjct: 553 MREQEVRLRQQEEKMQE 569
Score = 62.0 bits (149), Expect = 2e-09
Identities = 51/209 (24%), Positives = 111/209 (53%), Gaps = 44/209 (21%)
Query: 373 ELEL-MKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
E++L +K+LK +LE LL Q L+ DHL K+ ++ + ++ +E
Sbjct: 227 EIQLNVKELKRKLERAKLLL------PQQQLQAEADHLGKELQSVSAKLQAQVEENELWN 280
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
+ Q+Q + QE + ++++ +QE+ ++E
Sbjct: 281 RLNQQQEEKMWR---------------------------QEEKIQEREEKIQEQEEKIRE 313
Query: 492 QQRQLREQLQQLRE-QRKVQKQKKM----QEKKKLQEQKMQEKKKL--QEQRRQKKKKLQ 544
Q+ ++R Q + + E + K+++Q++M +EK + E+KM E++K+ QE++RQ+++K++
Sbjct: 314 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 373
Query: 545 ERKKWQGQ---MLQKEPEEEQQKQQLQEQ 570
E++K Q Q M ++E + +Q+++++EQ
Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEEKIREQ 402
Score = 59.3 bits (142), Expect = 1e-08
Identities = 46/210 (21%), Positives = 110/210 (52%), Gaps = 16/210 (7%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
+++ +K +EQ E + W + I+ Q+ + + +Q+Q + + E +
Sbjct: 370 EKIREQEKRQEQ-EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGEL---QEPCVAFNQQQLVQQEQH 488
++++K Q ++ K ++ ++ E+ QE + + ++ +QE
Sbjct: 429 EQEEKMRR-QEEKIREQEKKIR-----EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482
Query: 489 LKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQE-KKKLQEQRR---QKKKKLQ 544
++EQ+ ++R Q +++REQ K K ++ +EK + QE+ MQE ++K+ EQ ++++K+Q
Sbjct: 483 MQEQEEKMRRQEEKIREQEK--KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 540
Query: 545 ERKKWQGQMLQKEPEEEQQKQQLQEQPLKH 574
E+++ + +K E+E + +Q +E+ +H
Sbjct: 541 EQEEKMRRQEEKMREQEVRLRQQEEKMQEH 570
Score = 55.5 bits (132), Expect = 2e-07
Identities = 33/130 (25%), Positives = 81/130 (62%), Gaps = 9/130 (6%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQ--RKVQKQKKMQ---EKKKLQEQK 525
QE + ++++ +QE+ ++EQ+ ++EQ +++ EQ + +++ KMQ EK + QE+K
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Query: 526 MQE-KKKLQEQR---RQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNE 581
++E +KK++EQ R++++ +QE+++ + +K E+E++ Q+ +E+ + + +
Sbjct: 497 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQ 556
Query: 582 RVQICLQNPR 591
V++ Q +
Sbjct: 557 EVRLRQQEEK 566
Score = 47.4 bits (111), Expect = 5e-05
Identities = 42/182 (23%), Positives = 90/182 (49%), Gaps = 14/182 (7%)
Query: 469 ELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL--QEQKM 526
+L+ + QQQL + HL ++ + + +LQ E+ ++ + Q+++K+ QE+K+
Sbjct: 238 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI 297
Query: 527 QEKK-KLQEQR-----RQKKKKLQERKKWQGQMLQKEPEE-----EQQKQQLQEQPLKHN 575
QE++ K+QEQ +++K + QE W+ + + EE E++ ++L+E+ +
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 357
Query: 576 VIVGNERVQICLQNPRDVSVPLCNHPVRFLQAQPI-VPVQRAAEQQPSGFYQDENCGQQE 634
I E + + R+ + Q + I ++ EQ+ Q+E G+QE
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQE 417
Query: 635 DE 636
++
Sbjct: 418 EK 419
Score = 38.5 bits (88), Expect = 0.024
Identities = 23/100 (23%), Positives = 54/100 (54%), Gaps = 12/100 (12%)
Query: 486 EQHLKEQQRQLREQLQQLREQ------------RKVQKQKKMQEKKKLQEQKMQEKKKLQ 533
++ LKE+ +L+E+LQ + + RK+++ K + +++LQ + K+LQ
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 263
Query: 534 EQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
+ + +++E + W Q+E + +Q++++QE+ K
Sbjct: 264 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEK 303
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 65.1 bits (157), Expect = 2e-10
Identities = 62/293 (21%), Positives = 137/293 (46%), Gaps = 43/293 (14%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
+E EL +L +Q EE+ W + IQ + ++ + +++Q +R + E +
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMW 345
Query: 432 KKQQKQHAGQVK-----------RPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQ 480
+K++K + + K+ K L + +++E Q+
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI---RELEEKMHEQEKIRE------QE 396
Query: 481 QLVQQEQHLKEQQRQLREQLQQLREQRKVQKQ--------KKM--QEKKKLQEQKMQEKK 530
+ Q+E+ ++EQ+++ ++ + R++ K+++Q KKM QE+K +++K++E++
Sbjct: 397 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456
Query: 531 KLQEQR---RQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICL 587
K QEQ RQ++K ++ + W+ QKE EQ+K + QE+ + E++
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWR----QKEKMHEQEKIRKQEEKVWRQ----EEKMHDQE 508
Query: 588 QNPRDVSVPLCNHPVRFLQAQPIVPVQ--RAAEQQPSGFYQDENCGQQEDESQ 638
+ R+ + + + + + Q + EQ+ Q+E G+QE++ Q
Sbjct: 509 EKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQ 561
Score = 63.9 bits (154), Expect = 5e-10
Identities = 57/246 (23%), Positives = 121/246 (49%), Gaps = 30/246 (12%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K++EQ E++ W + I Q+ E + Q+Q R ++ E + +++
Sbjct: 427 EQEEKIREQ-EKKMWRQEEKIHEQEKIRE--EEKRQEQEEMWRQE--EKIREQEEIWRQK 481
Query: 435 QKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR 494
+K H + R ++ K + + QE + ++++ +QE+ ++EQ+
Sbjct: 482 EKMHEQEKIRK----QEEKVWRQEEKMHD-------QEEKIREQEEKMWRQEEKIREQEE 530
Query: 495 QLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQR----------RQKKKKL- 543
++REQ +++REQ ++ +++ +EK QE+KMQE++K++ Q R++K+K+
Sbjct: 531 KIREQEEKIREQEEMMQEQ--EEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIR 588
Query: 544 -QERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPV 602
QE K W+ + +E EE Q+Q+ + + + E++Q + R + V
Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 648
Query: 603 RFLQAQ 608
R Q +
Sbjct: 649 RLRQQE 654
Score = 63.9 bits (154), Expect = 5e-10
Identities = 46/208 (22%), Positives = 106/208 (50%), Gaps = 41/208 (19%)
Query: 372 QELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
+++ +K+++Q EE+ W + + +Q+ + + + +Q +R + E +
Sbjct: 482 EKMHEQEKIRKQ-EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
++++ + K GE +E Q+++ +QE+ ++E
Sbjct: 541 EQEEMMQEQEEKM-----------------------GEQEEKMQ--EQEKMRRQEEKIRE 575
Query: 492 QQRQLREQLQQLREQR--------KVQKQKKM----QEKKKLQEQKM-QEKKKLQEQRRQ 538
Q+ ++REQ +++REQ K+++Q++M +EK QE+KM ++++K+QEQ +
Sbjct: 576 QEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ--E 633
Query: 539 KKKKLQERKKWQGQMLQKEPEEEQQKQQ 566
+K + QE K W+ ++ ++ EE+ Q+ Q
Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Score = 60.8 bits (146), Expect = 5e-09
Identities = 56/219 (25%), Positives = 115/219 (52%), Gaps = 37/219 (16%)
Query: 373 ELEL-MKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVP 431
E++L +K+LK +LE LL Q L+ DHL K+ LQS A
Sbjct: 239 EIQLNVKELKRKLERAKLLL------PQQQLQAEADHLGKE-----------LQSVSA-- 279
Query: 432 KKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKE 491
K Q + ++ L ++ K + + + QE + ++++ +QE+ ++
Sbjct: 280 KLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR 339
Query: 492 QQRQLREQLQQLREQRKV--QKQKKM----------QEKKKLQEQKMQEKKKL--QEQRR 537
Q+ + E+ +++R Q ++ +K++KM +EK + E+KM E++K+ QE++R
Sbjct: 340 QEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 399
Query: 538 QKKKKLQERKKWQGQ---MLQKEPEEEQQKQQLQEQPLK 573
Q+++K++E++K Q Q M ++E + +Q+++++EQ K
Sbjct: 400 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 438
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/183 (20%), Positives = 89/183 (48%), Gaps = 16/183 (8%)
Query: 469 ELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL--QEQKM 526
+L+ + QQQL + HL ++ + + +LQ E+ ++ + Q+++K+ QE+K+
Sbjct: 250 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI 309
Query: 527 QE-KKKLQEQR------------RQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
QE ++K+QEQ +++K + QE W+ + + EE +++ + + L+
Sbjct: 310 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLE 369
Query: 574 HNVIVGNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQ 633
+ E+++ L+ + + + + I ++ EQ+ + Q+E +Q
Sbjct: 370 EMMWEKEEKIRE-LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 428
Query: 634 EDE 636
E++
Sbjct: 429 EEK 431
Score = 37.7 bits (86), Expect = 0.041
Identities = 22/96 (22%), Positives = 52/96 (54%), Gaps = 12/96 (12%)
Query: 486 EQHLKEQQRQLREQLQQLREQ------------RKVQKQKKMQEKKKLQEQKMQEKKKLQ 533
++ LKE+ +L+E+LQ + + RK+++ K + +++LQ + K+LQ
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQ 275
Query: 534 EQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQE 569
+ + +++E + W Q+E + +Q++++QE
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
>gi|93141033 PAX interacting protein 1 [Homo sapiens]
Length = 1069
Score = 63.9 bits (154), Expect = 5e-10
Identities = 51/200 (25%), Positives = 91/200 (45%), Gaps = 9/200 (4%)
Query: 395 IQNQQNALELMMDH--LQKQPNTLRHVVIPDLQSSEAVPKKQQKQHA---GQVKRPLPHP 449
+Q QQ A + H L QP + + Q P QQ H Q ++ HP
Sbjct: 401 LQQQQQAQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHP 460
Query: 450 KDVKCFCGLSLSNSLKNTGELQEP---CVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQ 506
L +L P F QQ +QQ+ H +Q + ++QL QL++Q
Sbjct: 461 HQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQ 520
Query: 507 RKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKL-QERKKWQGQMLQKEPEEEQQKQ 565
+ +Q++ Q+ ++ Q Q+M ++++ Q+ + Q L Q + Q Q+ ++P ++QQ+Q
Sbjct: 521 HSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQ 580
Query: 566 QLQEQPLKHNVIVGNERVQI 585
Q P +H + + V+I
Sbjct: 581 QPPPSPQQHQLFGHDPAVEI 600
Score = 37.0 bits (84), Expect = 0.070
Identities = 49/213 (23%), Positives = 88/213 (41%), Gaps = 24/213 (11%)
Query: 356 AQPLQPSSPVAYDIISQELELMKKLKEQLEERTWLL---HDAIQNQQNALELMMDHLQKQ 412
AQ Q PV + Q ++L ++ ++Q+ ++ + H Q QQ Q+Q
Sbjct: 407 AQQQQQQHPVLHLQPQQIMQLQQQQQQQISQQPYPQQPPHPFSQQQQQ---------QQQ 457
Query: 413 PNTLRHVVIPDLQSSEAVPKKQQKQHAGQ-VKRPLPHPKDVKCFCGLSLSNSLKNTGELQ 471
+ P S + + QQ+ H Q + RP + + L +LQ
Sbjct: 458 AH-------PHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPFQQQHALQQQFHQLQQHQLQ 510
Query: 472 EPCVAFNQQQ----LVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQ 527
+ +A QQQ QQ+Q +++QQ Q Q QQ ++ + Q + LQ Q
Sbjct: 511 QQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQQMQSQTAPHLSQTSQALQHQVPP 570
Query: 528 EKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEE 560
++ Q+Q++Q Q+ + + + PEE
Sbjct: 571 QQPPQQQQQQQPPPSPQQHQLFGHDPAVEIPEE 603
Score = 32.3 bits (72), Expect = 1.7
Identities = 47/226 (20%), Positives = 85/226 (37%), Gaps = 22/226 (9%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ 538
+QQ+ +Q L Q++ E +Q+Q++ Q Q+Q+ LQ Q+
Sbjct: 371 EQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQ-----QQQQQHPVLHLQPQQIM 425
Query: 539 KKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQN---PRDVSV 595
+ ++ Q+++ Q Q+ P Q+QQ Q+Q H +++Q Q P+ +
Sbjct: 426 QLQQQQQQQISQQPYPQQPPHPFSQQQQQQQQAHPHQ--FSQQQLQFPQQQLHPPQQLHR 483
Query: 596 P-----------LCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQ-QEDESQSFYPE 643
P LQ + Q A QQ Q + Q Q+ + Q + +
Sbjct: 484 PQQQLQPFQQQHALQQQFHQLQQHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQ 543
Query: 644 AYQGPPVNQLPLIDTSNSEAISSSSIPQFPITSDSTISTLETPQDY 689
Q +Q + S+A+ PQ P +PQ +
Sbjct: 544 QQQQQMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQH 589
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 63.2 bits (152), Expect = 9e-10
Identities = 52/202 (25%), Positives = 106/202 (52%), Gaps = 29/202 (14%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK 530
+E A +QQL QQ++ +E +RQL + Q+++++QK +++++L+EQ+ +EK+
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQLLAE-----RQKRIEEQK--EQRRRLEEQQRREKE 414
Query: 531 KLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNP 590
++Q R++++ +E+ + + + + E E+E +++QL+EQ ER+Q L+
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQA-------ERLQRQLKQE 467
Query: 591 RDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPV 650
RD V L + Q Q QR E++P Y++ G E ++ E + +
Sbjct: 468 RDYLVSLQH------QRQE----QRPVEKKPLYHYKE---GMSPSEKPAWAKEVEERSRL 514
Query: 651 NQ--LPLIDTSNSEAISSSSIP 670
N+ P + + IS ++P
Sbjct: 515 NRQSSPAMPHKVANRISDPNLP 536
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 63.2 bits (152), Expect = 9e-10
Identities = 52/202 (25%), Positives = 106/202 (52%), Gaps = 29/202 (14%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK 530
+E A +QQL QQ++ +E +RQL + Q+++++QK +++++L+EQ+ +EK+
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQLLAE-----RQKRIEEQK--EQRRRLEEQQRREKE 414
Query: 531 KLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNP 590
++Q R++++ +E+ + + + + E E+E +++QL+EQ ER+Q L+
Sbjct: 415 LRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQA-------ERLQRQLKQE 467
Query: 591 RDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPV 650
RD V L + Q Q QR E++P Y++ G E ++ E + +
Sbjct: 468 RDYLVSLQH------QRQE----QRPVEKKPLYHYKE---GMSPSEKPAWAKEVEERSRL 514
Query: 651 NQ--LPLIDTSNSEAISSSSIP 670
N+ P + + IS ++P
Sbjct: 515 NRQSSPAMPHKVANRISDPNLP 536
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 62.4 bits (150), Expect = 2e-09
Identities = 40/159 (25%), Positives = 87/159 (54%), Gaps = 9/159 (5%)
Query: 408 HLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNT 467
HLQ++P+ H P + Q+ H Q + P + + +++T
Sbjct: 1990 HLQQRPSGYVHQQAPTY--GHGLTSTQRFSH--QTLQQTPMISTMTPMSAQGVQAGVRST 2045
Query: 468 GELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQ 527
L E QQQ QQ+Q ++QQ+Q ++Q QQ R+ Q+Q+ ++++++ Q+Q+ Q
Sbjct: 2046 AILPE-----QQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ 2100
Query: 528 EKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQ 566
++++ Q+Q++Q++++ Q++++ Q Q +P+ + Q Q+
Sbjct: 2101 QQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQR 2139
Score = 57.4 bits (137), Expect = 5e-08
Identities = 30/95 (31%), Positives = 65/95 (68%), Gaps = 5/95 (5%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ 538
QQQ QQ+ H+++QQ+Q + L+Q ++Q++ Q+Q++ Q++++ Q+Q+ Q +++ Q+Q
Sbjct: 2069 QQQQQQQQYHIRQQQQQ--QILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAP 2126
Query: 539 KKKKLQERKKWQGQMLQKEPEEEQQK---QQLQEQ 570
+ + Q + ++Q Q LQ+ +++Q +QLQ+Q
Sbjct: 2127 PQPQPQSQPQFQRQGLQQTQQQQQTAALVRQLQQQ 2161
Score = 55.8 bits (133), Expect = 1e-07
Identities = 27/88 (30%), Positives = 59/88 (67%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ 538
QQQ QQ+Q ++Q ++Q QQ+ Q++ Q+Q++ Q++++ Q+Q+ Q++++ Q+Q++Q
Sbjct: 2063 QQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQ 2122
Query: 539 KKKKLQERKKWQGQMLQKEPEEEQQKQQ 566
+ Q + + Q Q ++ ++ QQ+QQ
Sbjct: 2123 QAAPPQPQPQSQPQFQRQGLQQTQQQQQ 2150
Score = 47.0 bits (110), Expect = 7e-05
Identities = 21/72 (29%), Positives = 53/72 (73%), Gaps = 3/72 (4%)
Query: 503 LREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQ 562
L EQ++ Q+Q++ Q++++ Q+Q+ Q++++ +++Q+++ L+++ Q Q Q++ +++Q
Sbjct: 2048 LPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQ---QQQQQQQQQQQQQ 2104
Query: 563 QKQQLQEQPLKH 574
Q+QQ Q+Q +H
Sbjct: 2105 QQQQQQQQQQQH 2116
Score = 47.0 bits (110), Expect = 7e-05
Identities = 26/93 (27%), Positives = 53/93 (56%), Gaps = 7/93 (7%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ 538
QQQ+++Q+Q ++QQ+Q ++Q QQ ++Q++ Q Q++ Q++ + + Q + + Q Q Q
Sbjct: 2084 QQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQ 2143
Query: 539 KKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQP 571
+ ++ Q+ Q+ +QQ Q QP
Sbjct: 2144 QTQQQQQTAALVRQL-------QQQLSNTQPQP 2169
Score = 44.3 bits (103), Expect = 4e-04
Identities = 32/148 (21%), Positives = 70/148 (47%), Gaps = 18/148 (12%)
Query: 467 TGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQ------------------LREQRK 508
T LQ+ + QQ L QR + LQQ +R
Sbjct: 1988 TRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPMSAQGVQAGVRSTAI 2047
Query: 509 VQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQ 568
+ +Q++ Q++++ Q+Q+ Q++++ Q+Q++ ++ Q+++ + Q Q++ +++QQ+QQ Q
Sbjct: 2048 LPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQ 2107
Query: 569 EQPLKHNVIVGNERVQICLQNPRDVSVP 596
+Q + ++ Q P+ S P
Sbjct: 2108 QQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
Score = 31.2 bits (69), Expect = 3.8
Identities = 25/112 (22%), Positives = 44/112 (39%), Gaps = 28/112 (25%)
Query: 543 LQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPV 602
L E+++ Q Q Q++ +++QQ+QQ Q+Q + +
Sbjct: 2048 LPEQQQQQQQQQQQQQQQQQQQQQQQQQ----------------------------QYHI 2079
Query: 603 RFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPEAYQGPPVNQLP 654
R Q Q I+ Q+ +QQ Q + QQ+ + Q + Q P P
Sbjct: 2080 RQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQP 2131
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 61.2 bits (147), Expect = 3e-09
Identities = 39/143 (27%), Positives = 83/143 (58%), Gaps = 17/143 (11%)
Query: 485 QEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQ 544
+ Q L++QQR+ E +QL +R+ + +++ +++++L+EQ+ +EK+ ++Q R++++ +
Sbjct: 369 RRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYE 428
Query: 545 ERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRF 604
E+ + + + + E E+E +++QL+EQ ER+Q L+ RD V L +
Sbjct: 429 EQMRREEERRRAEHEQEYKRKQLEEQRQA-------ERLQRQLKQERDYLVSLQH----- 476
Query: 605 LQAQPIVPVQRAAEQQPSGFYQD 627
Q Q QR E++P Y++
Sbjct: 477 -QRQE----QRPVEKKPLYHYKE 494
Score = 53.5 bits (127), Expect = 7e-07
Identities = 24/107 (22%), Positives = 67/107 (62%), Gaps = 11/107 (10%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ 538
+Q L ++++ ++EQ+ Q R +Q R +++++KQ++ ++++ +EQ +E+++ + + Q
Sbjct: 385 RQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQ 444
Query: 539 KKKKLQERKKWQGQMLQKEPEEE-----------QQKQQLQEQPLKH 574
+ K+ Q ++ Q + LQ++ ++E Q+++ ++++PL H
Sbjct: 445 EYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYH 491
Score = 41.6 bits (96), Expect = 0.003
Identities = 72/302 (23%), Positives = 127/302 (42%), Gaps = 71/302 (23%)
Query: 425 QSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQ 484
+ SEA+ ++Q +Q Q + H + + L+ K E +E +QQ +
Sbjct: 363 ERSEALRRQQLEQ---QQRENEEHKRQL-------LAERQKRIEEQKEQRRRLEEQQRRE 412
Query: 485 QE---QHLKEQQRQLREQLQQLREQRKVQ-----KQKKMQEKK---KLQEQKMQEKKKL- 532
+E Q +EQ+R EQ+++ E+R+ + K+K+++E++ +LQ Q QE+ L
Sbjct: 413 KELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLV 472
Query: 533 ------QEQRRQKKKKL---------QERKKWQGQM-----LQKEPEEEQQKQQLQEQPL 572
QEQR +KK L E+ W ++ ++ + Q + EQP
Sbjct: 473 SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPT 532
Query: 573 K------HNVIVGNERVQICLQN--PRDVSVPLCNHPVRFLQAQ---------PIVPVQR 615
K + V + RV++ QN P + PL +F ++ P VP QR
Sbjct: 533 KGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVP-QR 591
Query: 616 AAEQQP---------SGFYQDENCGQQEDESQSFYPEAYQGPPVNQLPLIDTSNSEAISS 666
P +G G Q + + P+ + P+ + PL TS+ + SS
Sbjct: 592 TTSISPALARKNSPGNGSALGPRLGSQPIRASN--PDLRRTEPILESPLQRTSSGSSSSS 649
Query: 667 SS 668
S+
Sbjct: 650 ST 651
Score = 40.0 bits (92), Expect = 0.008
Identities = 37/165 (22%), Positives = 79/165 (47%), Gaps = 13/165 (7%)
Query: 404 LMMDHLQKQPNT--LRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLS 461
L+ +H Q+ ++H I D Q +E + Q K H + K+ + + S S
Sbjct: 270 LVKNHSQRPATEQLMKHPFIRD-QPNERQVRIQLKDHIDRTKKKRGEKDETEY--EYSGS 326
Query: 462 NSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL 521
+ + EP N + Q +E+ + LR Q+ Q+Q++ +E K+
Sbjct: 327 EEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKR- 385
Query: 522 QEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQ 566
Q + E++K E++++++++L+E+ Q +KE ++Q+++Q
Sbjct: 386 --QLLAERQKRIEEQKEQRRRLEEQ-----QRREKELRKQQEREQ 423
Score = 34.3 bits (77), Expect = 0.45
Identities = 24/137 (17%), Positives = 68/137 (49%), Gaps = 6/137 (4%)
Query: 444 RPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR--QLREQLQ 501
R P+ + V+ + + K GE E ++ + ++E E L +
Sbjct: 290 RDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGEST 349
Query: 502 QLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ----KKKKLQERKKWQGQMLQKE 557
R+ ++Q K + + ++Q Q++++ +E +RQ ++K+++E+K+ + ++ +++
Sbjct: 350 LRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQ 409
Query: 558 PEEEQQKQQLQEQPLKH 574
E++ ++Q + + +H
Sbjct: 410 RREKELRKQQEREQRRH 426
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 61.2 bits (147), Expect = 3e-09
Identities = 39/143 (27%), Positives = 83/143 (58%), Gaps = 17/143 (11%)
Query: 485 QEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQ 544
+ Q L++QQR+ E +QL +R+ + +++ +++++L+EQ+ +EK+ ++Q R++++ +
Sbjct: 369 RRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYE 428
Query: 545 ERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRF 604
E+ + + + + E E+E +++QL+EQ ER+Q L+ RD V L +
Sbjct: 429 EQMRREEERRRAEHEQEYKRKQLEEQRQA-------ERLQRQLKQERDYLVSLQH----- 476
Query: 605 LQAQPIVPVQRAAEQQPSGFYQD 627
Q Q QR E++P Y++
Sbjct: 477 -QRQE----QRPVEKKPLYHYKE 494
Score = 53.5 bits (127), Expect = 7e-07
Identities = 24/107 (22%), Positives = 67/107 (62%), Gaps = 11/107 (10%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ 538
+Q L ++++ ++EQ+ Q R +Q R +++++KQ++ ++++ +EQ +E+++ + + Q
Sbjct: 385 RQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQ 444
Query: 539 KKKKLQERKKWQGQMLQKEPEEE-----------QQKQQLQEQPLKH 574
+ K+ Q ++ Q + LQ++ ++E Q+++ ++++PL H
Sbjct: 445 EYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYH 491
Score = 41.6 bits (96), Expect = 0.003
Identities = 72/302 (23%), Positives = 127/302 (42%), Gaps = 71/302 (23%)
Query: 425 QSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQ 484
+ SEA+ ++Q +Q Q + H + + L+ K E +E +QQ +
Sbjct: 363 ERSEALRRQQLEQ---QQRENEEHKRQL-------LAERQKRIEEQKEQRRRLEEQQRRE 412
Query: 485 QE---QHLKEQQRQLREQLQQLREQRKVQ-----KQKKMQEKK---KLQEQKMQEKKKL- 532
+E Q +EQ+R EQ+++ E+R+ + K+K+++E++ +LQ Q QE+ L
Sbjct: 413 KELRKQQEREQRRHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQERDYLV 472
Query: 533 ------QEQRRQKKKKL---------QERKKWQGQM-----LQKEPEEEQQKQQLQEQPL 572
QEQR +KK L E+ W ++ ++ + Q + EQP
Sbjct: 473 SLQHQRQEQRPVEKKPLYHYKEGMSPSEKPAWAKEIPHLVAVKSQGPALTASQSVHEQPT 532
Query: 573 K------HNVIVGNERVQICLQN--PRDVSVPLCNHPVRFLQAQ---------PIVPVQR 615
K + V + RV++ QN P + PL +F ++ P VP QR
Sbjct: 533 KGLSGFQEALNVTSHRVEMPRQNSDPTSENPPLPTRIEKFDRSSWLRQEEDIPPKVP-QR 591
Query: 616 AAEQQP---------SGFYQDENCGQQEDESQSFYPEAYQGPPVNQLPLIDTSNSEAISS 666
P +G G Q + + P+ + P+ + PL TS+ + SS
Sbjct: 592 TTSISPALARKNSPGNGSALGPRLGSQPIRASN--PDLRRTEPILESPLQRTSSGSSSSS 649
Query: 667 SS 668
S+
Sbjct: 650 ST 651
Score = 40.0 bits (92), Expect = 0.008
Identities = 37/165 (22%), Positives = 79/165 (47%), Gaps = 13/165 (7%)
Query: 404 LMMDHLQKQPNT--LRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLS 461
L+ +H Q+ ++H I D Q +E + Q K H + K+ + + S S
Sbjct: 270 LVKNHSQRPATEQLMKHPFIRD-QPNERQVRIQLKDHIDRTKKKRGEKDETEY--EYSGS 326
Query: 462 NSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL 521
+ + EP N + Q +E+ + LR Q+ Q+Q++ +E K+
Sbjct: 327 EEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKR- 385
Query: 522 QEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQ 566
Q + E++K E++++++++L+E+ Q +KE ++Q+++Q
Sbjct: 386 --QLLAERQKRIEEQKEQRRRLEEQ-----QRREKELRKQQEREQ 423
Score = 34.3 bits (77), Expect = 0.45
Identities = 24/137 (17%), Positives = 68/137 (49%), Gaps = 6/137 (4%)
Query: 444 RPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR--QLREQLQ 501
R P+ + V+ + + K GE E ++ + ++E E L +
Sbjct: 290 RDQPNERQVRIQLKDHIDRTKKKRGEKDETEYEYSGSEEEEEENDSGEPSSILNLPGEST 349
Query: 502 QLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQ----KKKKLQERKKWQGQMLQKE 557
R+ ++Q K + + ++Q Q++++ +E +RQ ++K+++E+K+ + ++ +++
Sbjct: 350 LRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQ 409
Query: 558 PEEEQQKQQLQEQPLKH 574
E++ ++Q + + +H
Sbjct: 410 RREKELRKQQEREQRRH 426
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 60.8 bits (146), Expect = 5e-09
Identities = 51/205 (24%), Positives = 106/205 (51%), Gaps = 18/205 (8%)
Query: 373 ELEL-MKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEA-- 429
E++L +K LK +LE LL Q L++ D L K+ ++ + ++ +E
Sbjct: 236 EIQLNVKDLKRKLERAQLLL------PQQQLQVEADRLGKELQSVSAKLQAQVEENELWN 289
Query: 430 VPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHL 489
+ +QQ++ + + + ++ C L + + QE + ++++ +QE +
Sbjct: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR-QEEKMHEQEEKIREQEDKM 348
Query: 490 KEQQRQLREQLQQLREQRKV---QKQKKMQEKKKLQEQ-----KMQEKKKLQEQRRQKKK 541
Q+ ++REQ +++REQ + Q++K ++ +K+QEQ + +EK + QE++RQ+K
Sbjct: 349 WRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKM 408
Query: 542 KLQERKKWQGQMLQKEPEEEQQKQQ 566
QE+K + +E EEE +Q+
Sbjct: 409 WRQEKKMREQDEKIREQEEEMWRQE 433
Score = 59.7 bits (143), Expect = 1e-08
Identities = 47/208 (22%), Positives = 107/208 (51%), Gaps = 27/208 (12%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K++EQ E++ W + I+ Q+ + + + +Q +R + E + +++
Sbjct: 336 EQEEKIREQ-EDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE 394
Query: 435 QKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR 494
+K + KR + K Q+ + ++++ +QE+ ++E +
Sbjct: 395 EKIREQEEKRQEKMWRQEKKM-------------REQDEKIREQEEEMWRQEEKIRELEE 441
Query: 495 QLREQLQQLREQRKVQKQKKMQEKKKLQEQK---MQEKKKLQEQR----RQKKKKLQERK 547
+++Q ++LRE ++K +E++K+QEQ+ ++++K+QEQ RQ+K QE K
Sbjct: 442 MMQDQEEKLREV----EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Query: 548 KWQGQ--MLQKEPEEEQQKQQLQEQPLK 573
W+ + M ++E + +Q++++QEQ K
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Score = 57.4 bits (137), Expect = 5e-08
Identities = 51/217 (23%), Positives = 111/217 (51%), Gaps = 34/217 (15%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K++EQ EE+ W + I+ Q ++ + + +Q +R E K+Q
Sbjct: 357 EQEEKIREQ-EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR----------EQEEKRQ 405
Query: 435 QKQHAGQVKRPLPHPK----DVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLK 490
+K + K K + + + L+ + QE + ++++ ++E+ ++
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 491 EQQRQLREQLQQLREQ-RKVQKQKKM----------QEKKKLQEQKM-QEKKKLQE---- 534
EQ+ +++ Q ++++EQ K +Q+K+ +EK QE+KM ++++K+QE
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Query: 535 -QRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
QR+++K + QE + WQ + +K E+E + Q+L+E+
Sbjct: 526 MQRQEEKMREQEVRLWQQE--EKMQEQEVRLQELEER 560
Score = 50.4 bits (119), Expect = 6e-06
Identities = 29/110 (26%), Positives = 70/110 (63%), Gaps = 9/110 (8%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK 530
QE + + ++ +QE+ + Q+ ++ EQ +++REQ K + +EK + QE+K++E++
Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE--DKMWRQEEKIREQEEKIREQE 366
Query: 531 ----KLQEQRRQKKKKLQERKK--W-QGQMLQKEPEEEQQKQQLQEQPLK 573
+ +E+ R++ +K+QE+++ W Q + ++++ E+ Q+K QE+ ++
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Score = 43.5 bits (101), Expect = 7e-04
Identities = 37/174 (21%), Positives = 88/174 (50%), Gaps = 14/174 (8%)
Query: 378 KKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQ 437
KK++EQ +E+ + + Q+ + + + +Q Q LR V + + E K Q+++
Sbjct: 413 KKMREQ-DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV---EEKMQEEEEKMQEQE 468
Query: 438 HAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLR 497
Q + ++ K + L QE + ++++ +QE+ + EQ+ +++
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLK--------QEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
Query: 498 EQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQG 551
EQ +++ QR+ +K ++ + + QE+KMQE++ ++ ++ KL ++ + G
Sbjct: 521 EQEEKM--QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLG 572
Score = 37.7 bits (86), Expect = 0.041
Identities = 27/121 (22%), Positives = 62/121 (51%), Gaps = 14/121 (11%)
Query: 465 KNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQ------------RKVQKQ 512
K T E P + + + +E LKE+ +L+E+L+ + + RK+++
Sbjct: 194 KLTKERDAPSLELYRNTITDEE--LKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251
Query: 513 KKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPL 572
+ + +++LQ + + K+LQ + + +++E + W Q+E + +Q++++QEQ
Sbjct: 252 QLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEE 311
Query: 573 K 573
K
Sbjct: 312 K 312
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 60.8 bits (146), Expect = 5e-09
Identities = 48/201 (23%), Positives = 109/201 (54%), Gaps = 14/201 (6%)
Query: 373 ELEL-MKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEA-- 429
E++L +K LK +LE LL Q L++ D L K+ ++ + ++ +E
Sbjct: 236 EIQLNVKDLKRKLERAQLLL------PQQQLQVEADRLGKELQSVSAKLQAQVEENELWN 289
Query: 430 VPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHL 489
+ +QQ++ + + + ++ C L + + QE + ++++ +QE +
Sbjct: 290 LLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWR-QEEKMHEQEEKIREQEDKM 348
Query: 490 KEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKW 549
Q+ ++REQ +++REQ +K + +EK + Q++K+QE++ +E RQ++K ++ +K
Sbjct: 349 WRQEEKIREQEEKIREQE--EKMWRQEEKIREQDEKIQEQE--EEMWRQEEKIREQEEKR 404
Query: 550 QGQMLQKEPEEEQQKQQLQEQ 570
Q +M ++E + +Q ++++EQ
Sbjct: 405 QEKMWRQEKKMREQDEKIREQ 425
Score = 59.7 bits (143), Expect = 1e-08
Identities = 47/208 (22%), Positives = 107/208 (51%), Gaps = 27/208 (12%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K++EQ E++ W + I+ Q+ + + + +Q +R + E + +++
Sbjct: 336 EQEEKIREQ-EDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQE 394
Query: 435 QKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQR 494
+K + KR + K Q+ + ++++ +QE+ ++E +
Sbjct: 395 EKIREQEEKRQEKMWRQEKKM-------------REQDEKIREQEEEMWRQEEKIRELEE 441
Query: 495 QLREQLQQLREQRKVQKQKKMQEKKKLQEQK---MQEKKKLQEQR----RQKKKKLQERK 547
+++Q ++LRE ++K +E++K+QEQ+ ++++K+QEQ RQ+K QE K
Sbjct: 442 MMQDQEEKLREV----EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Query: 548 KWQGQ--MLQKEPEEEQQKQQLQEQPLK 573
W+ + M ++E + +Q++++QEQ K
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Score = 57.4 bits (137), Expect = 5e-08
Identities = 51/217 (23%), Positives = 111/217 (51%), Gaps = 34/217 (15%)
Query: 375 ELMKKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQ 434
E +K++EQ EE+ W + I+ Q ++ + + +Q +R E K+Q
Sbjct: 357 EQEEKIREQ-EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR----------EQEEKRQ 405
Query: 435 QKQHAGQVKRPLPHPK----DVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLK 490
+K + K K + + + L+ + QE + ++++ ++E+ ++
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 491 EQQRQLREQLQQLREQ-RKVQKQKKM----------QEKKKLQEQKM-QEKKKLQE---- 534
EQ+ +++ Q ++++EQ K +Q+K+ +EK QE+KM ++++K+QE
Sbjct: 466 EQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEK 525
Query: 535 -QRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
QR+++K + QE + WQ + +K E+E + Q+L+E+
Sbjct: 526 MQRQEEKMREQEVRLWQQE--EKMQEQEVRLQELEER 560
Score = 50.4 bits (119), Expect = 6e-06
Identities = 29/110 (26%), Positives = 70/110 (63%), Gaps = 9/110 (8%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKK 530
QE + + ++ +QE+ + Q+ ++ EQ +++REQ K + +EK + QE+K++E++
Sbjct: 309 QEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE--DKMWRQEEKIREQEEKIREQE 366
Query: 531 ----KLQEQRRQKKKKLQERKK--W-QGQMLQKEPEEEQQKQQLQEQPLK 573
+ +E+ R++ +K+QE+++ W Q + ++++ E+ Q+K QE+ ++
Sbjct: 367 EKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMR 416
Score = 43.5 bits (101), Expect = 7e-04
Identities = 37/174 (21%), Positives = 88/174 (50%), Gaps = 14/174 (8%)
Query: 378 KKLKEQLEERTWLLHDAIQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQ 437
KK++EQ +E+ + + Q+ + + + +Q Q LR V + + E K Q+++
Sbjct: 413 KKMREQ-DEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV---EEKMQEEEEKMQEQE 468
Query: 438 HAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLR 497
Q + ++ K + L QE + ++++ +QE+ + EQ+ +++
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLK--------QEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
Query: 498 EQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQG 551
EQ +++ QR+ +K ++ + + QE+KMQE++ ++ ++ KL ++ + G
Sbjct: 521 EQEEKM--QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLG 572
Score = 36.6 bits (83), Expect = 0.091
Identities = 22/100 (22%), Positives = 55/100 (55%), Gaps = 12/100 (12%)
Query: 486 EQHLKEQQRQLREQLQQLREQ------------RKVQKQKKMQEKKKLQEQKMQEKKKLQ 533
++ LKE+ +L+E+L+ + + RK+++ + + +++LQ + + K+LQ
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ 272
Query: 534 EQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLK 573
+ + +++E + W Q+E + +Q++++QEQ K
Sbjct: 273 SVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEK 312
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 59.3 bits (142), Expect = 1e-08
Identities = 31/101 (30%), Positives = 63/101 (62%), Gaps = 1/101 (0%)
Query: 472 EPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKLQEQKMQEKKK 531
+P + QQ QQ+Q ++QQ+Q ++Q QQ ++Q++ Q+Q+ ++ Q+Q+ +
Sbjct: 580 KPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQ 639
Query: 532 LQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPL 572
Q+Q++Q++++ Q++++ Q Q Q++P Q Q L QPL
Sbjct: 640 QQQQQQQQQQQQQQQQQQQQQQQQQQP-SSQPAQSLPSQPL 679
Score = 58.9 bits (141), Expect = 2e-08
Identities = 32/110 (29%), Positives = 63/110 (57%), Gaps = 10/110 (9%)
Query: 472 EPCVAFNQQQLVQQEQH----------LKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL 521
+P FN Q QQ L Q+Q ++Q QQ ++Q++ Q+Q++ Q++++
Sbjct: 557 KPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 616
Query: 522 QEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQP 571
Q+Q+ Q+Q++Q Q++++ Q Q Q++ +++QQ+QQ Q+QP
Sbjct: 617 QQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQP 666
Score = 58.2 bits (139), Expect = 3e-08
Identities = 34/108 (31%), Positives = 66/108 (61%), Gaps = 14/108 (12%)
Query: 479 QQQLVQQEQHLKEQQRQLREQLQQLREQR---KVQKQKKMQEKKKLQEQKMQEKKKLQEQ 535
QQQ QQ+Q ++QQ+Q ++Q QQ ++Q+ Q+Q++ Q Q+Q+ Q++++ Q+Q
Sbjct: 593 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQ 652
Query: 536 RRQKKKKLQERKKWQGQMLQKEPEEE--------QQK---QQLQEQPL 572
++Q++++ Q++++ Q Q P + QQK QQ+Q QP+
Sbjct: 653 QQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPI 700
Score = 43.1 bits (100), Expect = 0.001
Identities = 52/251 (20%), Positives = 103/251 (41%), Gaps = 36/251 (14%)
Query: 343 PEDSVDLGAAGASAQP------LQPSSPVAYDIISQELELMKKLKEQLEERTWLL--HDA 394
P+ S G AG S Q + + P A L+++ + K Q R+++ H A
Sbjct: 492 PQSSPMPGVAGGSGQSKVMANYMYKAGPSAQ---GGHLDVLMQQKPQDLSRSFINNPHPA 548
Query: 395 IQNQQNALELMMDHLQKQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKC 454
++ +Q + + Q N V+P + QQ+Q Q ++
Sbjct: 549 MEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQ--------- 599
Query: 455 FCGLSLSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLRE------QLQQLREQRK 508
+ + Q+ QQQ QQ+ + QQ+Q ++ Q QQ ++Q++
Sbjct: 600 ----------QQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQ 649
Query: 509 VQKQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQ 568
Q+Q++ Q++++ Q+Q + + + + L ++K Q +Q +P Q Q
Sbjct: 650 QQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGYQVSQ 709
Query: 569 EQPLKHNVIVG 579
+Q + +VG
Sbjct: 710 QQRQDQHSVVG 720
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 59.3 bits (142), Expect = 1e-08
Identities = 55/225 (24%), Positives = 108/225 (48%), Gaps = 38/225 (16%)
Query: 458 LSLSNSLKNTGELQEPCVAFNQQQLVQQEQH----LKEQQR---QLREQLQQLREQRKVQ 510
L L K E +QQL +QE++ L E+Q+ Q +EQ ++L EQ++ +
Sbjct: 357 LRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRE 416
Query: 511 KQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
++ + Q++++ + ++ +EK++L+E R++K++ +ER++ + + + E E+E ++QL+E+
Sbjct: 417 REARRQQEREQRRREQEEKRRLEELERRRKEE-EERRRAEEEKRRVEREQEYIRRQLEEE 475
Query: 571 PLKHNVIVGNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENC 630
+H ++ + +Q D P HP Q P
Sbjct: 476 Q-RHLEVLQQQLLQEQAMLLHDHRRP---HPQHSQQPPP--------------------- 510
Query: 631 GQQEDESQSFY---PEAYQGPP--VNQLPLIDTSNSEAISSSSIP 670
QQE SF+ P+A+ P ++P+ TS S +S P
Sbjct: 511 PQQERSKPSFHAPEPKAHYEPADRAREVPVRTTSRSPVLSRRDSP 555
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/180 (22%), Positives = 92/180 (51%), Gaps = 19/180 (10%)
Query: 405 MMDHLQKQPNT---LRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLS 461
++ + ++P+T L+H I D Q +E + Q K H + ++ + + S
Sbjct: 270 LVKNYMQRPSTEQLLKHPFIRD-QPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEE 328
Query: 462 NSLKNTGELQEPCVAFN-------QQQLVQQEQHLKEQQRQLREQL----QQLREQRKVQ 510
+ + EP N ++ ++ +Q KE+ LR Q QQLREQ + +
Sbjct: 329 EEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYK 388
Query: 511 KQKKMQEKKKLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQ 570
+Q + +K++++QK Q ++ ++QRR+++ + Q+ ++ + ++E EE+++ ++L+ +
Sbjct: 389 RQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQR----RREQEEKRRLEELERR 444
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 59.3 bits (142), Expect = 1e-08
Identities = 59/279 (21%), Positives = 129/279 (46%), Gaps = 25/279 (8%)
Query: 405 MMDHLQKQPNTLRHVVI--PDLQSSEAVPKKQQKQHAGQVKRPLPHP--KDVKCFC-GLS 459
+++ ++ + L H + P SS P KQH+ P P + K F G +
Sbjct: 271 VLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKFVKGST 330
Query: 460 LSNSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKK 519
N L+ + + + ++++ LKE+ ++ +E+ ++ +E+ K K+K+ +EK+
Sbjct: 331 EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR 390
Query: 520 KLQEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVG 579
+ E++ EK++L+E+RR+++++ E K + +K +EE+++ + +E+ +K
Sbjct: 391 EKDEKEKAEKQRLKEERRKERQEALEAK-----LEEKRKKEEEKRLREEEKRIK------ 439
Query: 580 NERVQIC--LQNPRDVSVP-----LCNHPVRF-LQAQPIVPVQRAAEQQPSGFYQDENCG 631
E+ +I Q P+ P C F ++ ++ +R P Q +
Sbjct: 440 AEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIKEHMVLAPRRRTAFHPDLCSQLDQLL 499
Query: 632 QQEDESQSFYPEAYQGPPVNQLPL-IDTSNSEAISSSSI 669
QQ+ SF + P+ P + T N++ +S +
Sbjct: 500 QQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVV 538
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/219 (23%), Positives = 113/219 (51%), Gaps = 34/219 (15%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQL----REQLQQLREQRKVQKQKKMQEKKKLQEQKM 526
+E A +QQL QQ++ +E +RQL ++++++ +EQR+ ++++ +EK+ ++Q+
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQER 421
Query: 527 QEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIV-------- 578
++++ +EQ R+++++ R + + + ++++ EEEQ++ ++ +Q L H +
Sbjct: 422 EQRRHYEEQMRREEER--RRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQ 479
Query: 579 -----GNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQ 633
ER+Q L+ RD V L + Q Q QR E++P Y++ G
Sbjct: 480 LEEQRQAERLQRQLKQERDYLVSLQH------QRQE----QRPVEKKPLYHYKE---GMS 526
Query: 634 EDESQSFYPEAYQGPPVNQ--LPLIDTSNSEAISSSSIP 670
E ++ E + +N+ P + + IS ++P
Sbjct: 527 PSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLP 565
Score = 40.0 bits (92), Expect = 0.008
Identities = 37/165 (22%), Positives = 79/165 (47%), Gaps = 13/165 (7%)
Query: 404 LMMDHLQKQPNT--LRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLS 461
L+ +H Q+ ++H I D Q +E + Q K H + K+ + + S S
Sbjct: 270 LVKNHSQRPATEQLMKHPFIRD-QPNERQVRIQLKDHIDRTKKKRGEKDETEY--EYSGS 326
Query: 462 NSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL 521
+ + EP N + Q +E+ + LR Q+ Q+Q++ +E K+
Sbjct: 327 EEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKR- 385
Query: 522 QEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQ 566
Q + E++K E++++++++L+E+ Q +KE ++Q+++Q
Sbjct: 386 --QLLAERQKRIEEQKEQRRRLEEQ-----QRREKELRKQQEREQ 423
Score = 39.3 bits (90), Expect = 0.014
Identities = 71/361 (19%), Positives = 138/361 (38%), Gaps = 31/361 (8%)
Query: 294 NPLYRADPVDLEFSVDQVDSVDQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAG 353
+P R P + + + D +D+ ++ E + +G + + DS +
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRT---KKKRGEKDETEYEYSGSEEEEEENDSGE----P 338
Query: 354 ASAQPLQPSSPVAYDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDH---LQ 410
+S L S + D + L+L K + + R L +N+++ +L+ + ++
Sbjct: 339 SSILNLPGESTLRRDFL--RLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIE 396
Query: 411 KQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGEL 470
+Q R + + Q E +KQQ++ + ++ + + E
Sbjct: 397 EQKEQRRR--LEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEE 454
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKK--MQEKKKLQEQKMQE 528
Q QQ L +Q L+ +++QL EQ Q R QR++++++ + + + QEQ+ E
Sbjct: 455 QRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVE 514
Query: 529 KKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQ 588
KK L + E+ W KE EE + + + H V R+
Sbjct: 515 KKPLYHYKEGMSP--SEKPAW-----AKEVEERSRLNRQSSPAMPHKVA---NRISDPNL 564
Query: 589 NPRDVS-----VPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPE 643
PR S V P P +P A + Q ++ +Q + S + E
Sbjct: 565 PPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQE 624
Query: 644 A 644
A
Sbjct: 625 A 625
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/219 (23%), Positives = 113/219 (51%), Gaps = 34/219 (15%)
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQL----REQLQQLREQRKVQKQKKMQEKKKLQEQKM 526
+E A +QQL QQ++ +E +RQL ++++++ +EQR+ ++++ +EK+ ++Q+
Sbjct: 362 KERSEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQER 421
Query: 527 QEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIV-------- 578
++++ +EQ R+++++ R + + + ++++ EEEQ++ ++ +Q L H +
Sbjct: 422 EQRRHYEEQMRREEER--RRAEHEQEYIRRQLEEEQRQLEILQQQLLHEQALLLEYKRKQ 479
Query: 579 -----GNERVQICLQNPRDVSVPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQ 633
ER+Q L+ RD V L + Q Q QR E++P Y++ G
Sbjct: 480 LEEQRQAERLQRQLKQERDYLVSLQH------QRQE----QRPVEKKPLYHYKE---GMS 526
Query: 634 EDESQSFYPEAYQGPPVNQ--LPLIDTSNSEAISSSSIP 670
E ++ E + +N+ P + + IS ++P
Sbjct: 527 PSEKPAWAKEVEERSRLNRQSSPAMPHKVANRISDPNLP 565
Score = 40.0 bits (92), Expect = 0.008
Identities = 37/165 (22%), Positives = 79/165 (47%), Gaps = 13/165 (7%)
Query: 404 LMMDHLQKQPNT--LRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLS 461
L+ +H Q+ ++H I D Q +E + Q K H + K+ + + S S
Sbjct: 270 LVKNHSQRPATEQLMKHPFIRD-QPNERQVRIQLKDHIDRTKKKRGEKDETEY--EYSGS 326
Query: 462 NSLKNTGELQEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKKMQEKKKL 521
+ + EP N + Q +E+ + LR Q+ Q+Q++ +E K+
Sbjct: 327 EEEEEENDSGEPSSILNLPGESTLRRDFLRLQLANKERSEALRRQQLEQQQRENEEHKR- 385
Query: 522 QEQKMQEKKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQ 566
Q + E++K E++++++++L+E+ Q +KE ++Q+++Q
Sbjct: 386 --QLLAERQKRIEEQKEQRRRLEEQ-----QRREKELRKQQEREQ 423
Score = 39.3 bits (90), Expect = 0.014
Identities = 71/361 (19%), Positives = 138/361 (38%), Gaps = 31/361 (8%)
Query: 294 NPLYRADPVDLEFSVDQVDSVDQEGPMDQQDPENPVAPLDQAGLMDPVDPEDSVDLGAAG 353
+P R P + + + D +D+ ++ E + +G + + DS +
Sbjct: 286 HPFIRDQPNERQVRIQLKDHIDRT---KKKRGEKDETEYEYSGSEEEEEENDSGE----P 338
Query: 354 ASAQPLQPSSPVAYDIISQELELMKKLKEQLEERTWLLHDAIQNQQNALELMMDH---LQ 410
+S L S + D + L+L K + + R L +N+++ +L+ + ++
Sbjct: 339 SSILNLPGESTLRRDFL--RLQLANKERSEALRRQQLEQQQRENEEHKRQLLAERQKRIE 396
Query: 411 KQPNTLRHVVIPDLQSSEAVPKKQQKQHAGQVKRPLPHPKDVKCFCGLSLSNSLKNTGEL 470
+Q R + + Q E +KQQ++ + ++ + + E
Sbjct: 397 EQKEQRRR--LEEQQRREKELRKQQEREQRRHYEEQMRREEERRRAEHEQEYIRRQLEEE 454
Query: 471 QEPCVAFNQQQLVQQEQHLKEQQRQLREQLQQLREQRKVQKQKK--MQEKKKLQEQKMQE 528
Q QQ L +Q L+ +++QL EQ Q R QR++++++ + + + QEQ+ E
Sbjct: 455 QRQLEILQQQLLHEQALLLEYKRKQLEEQRQAERLQRQLKQERDYLVSLQHQRQEQRPVE 514
Query: 529 KKKLQEQRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQ 588
KK L + E+ W KE EE + + + H V R+
Sbjct: 515 KKPLYHYKEGMSP--SEKPAW-----AKEVEERSRLNRQSSPAMPHKVA---NRISDPNL 564
Query: 589 NPRDVS-----VPLCNHPVRFLQAQPIVPVQRAAEQQPSGFYQDENCGQQEDESQSFYPE 643
PR S V P P +P A + Q ++ +Q + S + E
Sbjct: 565 PPRSESFSISGVQPARTPPMLRPVDPQIPHLVAVKSQGPALTASQSVHEQPTKGLSGFQE 624
Query: 644 A 644
A
Sbjct: 625 A 625
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,297,239
Number of Sequences: 37866
Number of extensions: 1682665
Number of successful extensions: 41934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 946
Number of HSP's successfully gapped in prelim test: 824
Number of HSP's that attempted gapping in prelim test: 11008
Number of HSP's gapped (non-prelim): 13140
length of query: 773
length of database: 18,247,518
effective HSP length: 110
effective length of query: 663
effective length of database: 14,082,258
effective search space: 9336537054
effective search space used: 9336537054
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.