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Search of human proteins with 157739936
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157739936 chromosome 10 open reading frame 68 [Homo sapiens]
(628 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157739936 chromosome 10 open reading frame 68 [Homo sapiens] 1235 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 55 3e-07
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 54 4e-07
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 54 4e-07
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 53 7e-07
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 53 7e-07
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 52 2e-06
gi|148746195 trichohyalin [Homo sapiens] 52 2e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 51 3e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 50 6e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 50 6e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 50 8e-06
gi|4758646 kinesin family member 3B [Homo sapiens] 49 2e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 2e-05
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 47 5e-05
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 46 9e-05
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 46 9e-05
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 46 9e-05
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 45 2e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 45 2e-04
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 45 2e-04
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof... 45 2e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 44 3e-04
gi|58530840 desmoplakin isoform I [Homo sapiens] 44 4e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 44 4e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 44 4e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 44 4e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 44 4e-04
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 44 4e-04
gi|229577000 ecotropic viral integration site 5-like isoform 1 [... 44 6e-04
>gi|157739936 chromosome 10 open reading frame 68 [Homo sapiens]
Length = 628
Score = 1235 bits (3195), Expect = 0.0
Identities = 628/628 (100%), Positives = 628/628 (100%)
Query: 1 MTEEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNEN 60
MTEEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNEN
Sbjct: 1 MTEEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNEN 60
Query: 61 LILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLP 120
LILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLP
Sbjct: 61 LILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLP 120
Query: 121 REKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKL 180
REKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKL
Sbjct: 121 REKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKL 180
Query: 181 QMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIK 240
QMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIK
Sbjct: 181 QMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIK 240
Query: 241 KKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSK 300
KKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSK
Sbjct: 241 KKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSK 300
Query: 301 SFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYP 360
SFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYP
Sbjct: 301 SFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYP 360
Query: 361 ETVLKHLKGVNGKDIIKHLINIQSKSHGETDKNFFAYATGRGLMKESTTTQLKSHPETDK 420
ETVLKHLKGVNGKDIIKHLINIQSKSHGETDKNFFAYATGRGLMKESTTTQLKSHPETDK
Sbjct: 361 ETVLKHLKGVNGKDIIKHLINIQSKSHGETDKNFFAYATGRGLMKESTTTQLKSHPETDK 420
Query: 421 EFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVEPLT 480
EFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVEPLT
Sbjct: 421 EFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVEPLT 480
Query: 481 NAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQRQEGIFTRSITPSKFPTKVINLSPFEN 540
NAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQRQEGIFTRSITPSKFPTKVINLSPFEN
Sbjct: 481 NAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQRQEGIFTRSITPSKFPTKVINLSPFEN 540
Query: 541 KEETYEYSSPYVTAPSKAIYRTYRAGPSFSKDIHLPLLNQLPSGHSKVVTLSQKTIEFTL 600
KEETYEYSSPYVTAPSKAIYRTYRAGPSFSKDIHLPLLNQLPSGHSKVVTLSQKTIEFTL
Sbjct: 541 KEETYEYSSPYVTAPSKAIYRTYRAGPSFSKDIHLPLLNQLPSGHSKVVTLSQKTIEFTL 600
Query: 601 PTVTNTVGKPTYKVLHAAARKSVPHPYF 628
PTVTNTVGKPTYKVLHAAARKSVPHPYF
Sbjct: 601 PTVTNTVGKPTYKVLHAAARKSVPHPYF 628
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 54.7 bits (130), Expect = 3e-07
Identities = 92/448 (20%), Positives = 183/448 (40%), Gaps = 52/448 (11%)
Query: 11 EKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMS 70
+K QAH + E+L +E ++ KLQ++K + K E L+L Q+S
Sbjct: 946 KKMQAHIQDLEEQL---DEEEGARQKLQLEKVTAEAKIK-----KMEEEILLLEDQNSKF 997
Query: 71 KSEMQVKEQRTLKGQRIITHDEEPGKNLVL---EHQDSVSKLEMQIEKTKKLPREKRHST 127
E ++ E R + + +EE KNL + + +S LE +++K +K R++
Sbjct: 998 IKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEK-TRQELEKA 1056
Query: 128 HDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKK 187
+ GE L QD ++++Q Q++ KLQ+ +K++
Sbjct: 1057 KRKLDGETTDL--QDQIAELQAQID------------------------ELKLQLAKKEE 1090
Query: 188 ITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDIS-- 245
G R + N + V ++ ++++ ++ + R+K E +K+D+S
Sbjct: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKA---EKQKRDLSEE 1147
Query: 246 LEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQS-KSFPG 304
LE L E + L T Q ++ ++++ ++ L+ AL N E + Q +
Sbjct: 1148 LEALKTELEDTL-----DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHA 1202
Query: 305 PDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVL 364
+E+L++ + ++K ETD + + + +++ KRK V
Sbjct: 1203 TALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQ 1262
Query: 365 K-HLKGVNGKDIIKHLINIQSKSHGETD--KNFFAYATGRGLMKESTTTQLKSHPETDKE 421
+ H K G + L SK E D A +G+ L+S + +E
Sbjct: 1263 ELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQE 1322
Query: 422 FLADAIGRGIIIGPITTQLKSHRETDKE 449
L + + + + QL+ + + +E
Sbjct: 1323 LLQEETRQKLNLSSRIRQLEEEKNSLQE 1350
Score = 47.8 bits (112), Expect = 3e-05
Identities = 79/380 (20%), Positives = 164/380 (43%), Gaps = 45/380 (11%)
Query: 8 QAAEKSQAHNEVPNERLVVEHQESLSKTKL--QIKKQETSTEQPLTTPDKEPNENLILRH 65
+ A++ +A+ E + L +++E + K+ Q+K + + L +E + +
Sbjct: 1213 EQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272
Query: 66 QDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRH 125
+ + +E K Q L + T EE K + +D+ S LE Q++ T++L +E+
Sbjct: 1273 RLRVELAEKASKLQNEL--DNVSTLLEEAEKKGIKFAKDAAS-LESQLQDTQELLQEETR 1329
Query: 126 STHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQ----------D 175
+ S + + ++S L+ Q+ E E R +K + + D
Sbjct: 1330 QKLNLSSRIRQLEEEKNS-------LQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDD 1382
Query: 176 SVSKLQMQE--KKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEK-KQINSGVERH 232
+ ++ E KKK+ E + R+ E ++ + K+K ++Q++ + ++
Sbjct: 1383 DLGTIESLEEAKKKLLKDAEALSQRL---EEKALAYDKLEKTKNRLQQELDDLTVDLDHQ 1439
Query: 233 KTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRL-L 291
+ ++KK + LL EEK + +R + + +A+ K+T SL AL L
Sbjct: 1440 RQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAE-AREKETKALSLARALEEALEA 1498
Query: 292 NDEFKTQSKSFPG--PDIEQLTDAFGRDI---------LKDEFKTRSKSLPETDERLHST 340
+EF+ Q+K D+ D G+++ L+ + + L E ++ L +T
Sbjct: 1499 KEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQAT 1558
Query: 341 TE---RGTIN-DAIKTQLKR 356
+ R +N A+K Q +R
Sbjct: 1559 EDAKLRLEVNMQAMKAQFER 1578
Score = 32.7 bits (73), Expect = 1.0
Identities = 30/126 (23%), Positives = 56/126 (44%), Gaps = 13/126 (10%)
Query: 152 EIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQ 211
E Q EGE + K+ + + ++ Q+Q + ++ E R+ + + +
Sbjct: 866 EKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILH 925
Query: 212 DSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQ-AK 270
D +S+++ +E ER++ E KK ++ L EE+ L E +KLQ K
Sbjct: 926 DLESRVEEEE--------ERNQILQNEKKKMQAHIQDL--EEQ--LDEEEGARQKLQLEK 973
Query: 271 VTSRKK 276
VT+ K
Sbjct: 974 VTAEAK 979
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 53.9 bits (128), Expect = 4e-07
Identities = 94/451 (20%), Positives = 180/451 (39%), Gaps = 60/451 (13%)
Query: 34 KTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRTLKGQRIITHDEE 93
K LQ + ++ E + + I + ++++ + LK + I E
Sbjct: 523 KCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAE--IVSASE 580
Query: 94 PGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDEESGENPMLK------HQDSVSKI 147
K L L+H+ V+ ++++E +K + + E L+ H++ +SK+
Sbjct: 581 SRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKL 640
Query: 148 QVQLEIQETSEGEGRSIPDKNSMFVH-QDSVSKLQMQEKKKITPGRERRNTRIVVPNENV 206
+ LEI+ E K+++ +H + + LQ + +KI + ++ I N+ +
Sbjct: 641 KEDLEIEHRINIEKL----KDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLI 696
Query: 207 ISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKK 266
+ + SKL+ ++ +NS E L+I + +E L EEK E + ++
Sbjct: 697 LEI-----SKLKDLQQSLVNSKSEE---MTLQINELQKEIEILRQEEKEK-GTLEQEVQE 747
Query: 267 LQAKVT------SRKKTDIESLRGALGRR--LLNDEFKTQSKSFPGPDIEQLTDAFGRDI 318
LQ K K+ D++ L +L DE KT I R I
Sbjct: 748 LQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLK---IHTPVSQEERLI 804
Query: 319 LKDEFKTRSKS---------LPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKG 369
D K++SK L E +E L + +N+ I+ Q S+ E +
Sbjct: 805 FLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQ--LNEEIEKQRNTFSFAEKNFE---- 858
Query: 370 VNGKDIIKH---LINIQSKSHGETDKNFFAYATGRGLMKES--------TTTQLKSHP-E 417
VN +++ + L+ ++ +K Y + + E TT ++KS +
Sbjct: 859 VNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFD 918
Query: 418 TDKEFLADAIGRGIIIGPITTQLKSHRETDK 448
DK F+A+ + G ++ TT+L E K
Sbjct: 919 EDKTFVAETLEMGEVVEKDTTELMEKLEVTK 949
Score = 42.0 bits (97), Expect = 0.002
Identities = 68/313 (21%), Positives = 136/313 (43%), Gaps = 42/313 (13%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQ--IKKQETSTEQPLTT---PDKEP 57
E+Q Q EK + E+L V+ Q + LQ +K E E+ ++ ++E
Sbjct: 1991 EQQLLQETEK------LMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEK 2044
Query: 58 NENLILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTK 117
N L+ Q + + + K ++ L Q I D E +++ Q + KLE Q++
Sbjct: 2045 NTELMDLRQQNQALEKQLEKMRKFLDEQAI---DREHERDVF---QQEIQKLEQQLKVVP 2098
Query: 118 KLPREKRHSTHDEESGENPMLKHQDS-----VSKIQVQLEIQETSEG----EGRSIPDKN 168
+ H T + E N + + D +SK Q+Q +IQE +E E R +
Sbjct: 2099 RFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQ 2158
Query: 169 SMFVHQDSVSKLQMQEKKKITPGRERRNTRIV-VPNENVISVHQDSKSKLQMQEKKQINS 227
++ V D+ K++ +R++ V E + V ++ +++K+I +
Sbjct: 2159 ALLVSADTFQKVE-----------DRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITN 2207
Query: 228 GVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALG 287
E+ + F E++ K+ ++ L + ++ S ++ ++L+ + K D+E L A+
Sbjct: 2208 LEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQE-NKLFKDDMEKLGLAIK 2266
Query: 288 RRLLNDEFKTQSK 300
+D TQ +
Sbjct: 2267 E---SDAMSTQDQ 2276
Score = 40.4 bits (93), Expect = 0.005
Identities = 58/278 (20%), Positives = 116/278 (41%), Gaps = 49/278 (17%)
Query: 27 EHQESLSKTKLQIKKQETSTEQPL--------TTPDKEPNENLILRHQDSM-SKSEMQVK 77
E Q +L K K ++ + E ++ L + + NL+L Q + ++S+ +++
Sbjct: 3219 ELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIE 3278
Query: 78 EQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKR-HSTHDEESG--- 133
QR L ++ EE G+NL L+ K+ ++ E + L RE+ H+ G
Sbjct: 3279 SQRMLYDAQL---SEEQGRNLELQVLLESEKVRIR-EMSSTLDRERELHAQLQSSDGTGQ 3334
Query: 134 ENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRE 193
P L +D + ++Q QLE + + E + +K + DS+ Q EK +
Sbjct: 3335 SRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKL----DSLQTRQQMEKDR------ 3384
Query: 194 RRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEE 253
Q + LQ +++ + H E++ K L+ L E+
Sbjct: 3385 -----------------QVHRKTLQTEQEANTEGQKKMH-----ELQSKVEDLQRQLEEK 3422
Query: 254 KVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLL 291
+ + + + + ++LQ + +K ++E RR+L
Sbjct: 3423 RQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRIL 3460
Score = 37.4 bits (85), Expect = 0.042
Identities = 65/298 (21%), Positives = 124/298 (41%), Gaps = 40/298 (13%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI 62
E+Q A E+ V E +Q L++ +K++ S E+ + P E + N+
Sbjct: 2399 EQQVETANEEMTFMKNVLKETNFKMNQ--LTQELFSLKRERESVEKIQSIP--ENSVNVA 2454
Query: 63 LRHQDSMSKSEMQV----KEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIE-KTK 117
+ H S K E++V ++L+ Q EE GK ++ + + +LE + K
Sbjct: 2455 IDHL-SKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDL 2513
Query: 118 KLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSV 177
+L + + +E G+ Q + +Q +E + + V Q +
Sbjct: 2514 ELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAA------------LVSQIQL 2561
Query: 178 SKLQ-----MQEKKKITPGRERRNTRIVVPNENVISVHQDSK----SKLQMQEKKQINSG 228
+Q Q+ + I+ ER N +N+ + +D S L ++ + +
Sbjct: 2562 EAVQEYAKFCQDNQTISSEPERTNI------QNLNQLREDELGSDISALTLRISELESQV 2615
Query: 229 VERHKTFPLEIKKKDISLEHLLPEEKVLLSRS---ESQTKKLQAKVTSRKKTDIESLR 283
VE H + LE ++ +I+ +++L +EK LL E KK + K R D+E L+
Sbjct: 2616 VEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLK 2673
Score = 35.0 bits (79), Expect = 0.21
Identities = 74/387 (19%), Positives = 150/387 (38%), Gaps = 45/387 (11%)
Query: 10 AEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSM 69
AE +A E +L+ H+E LSK K++ E + + N + + Q
Sbjct: 615 AESQEAELERLRTQLLFSHEEELSKL-----KEDLEIEHRINIEKLKDNLGIHYKQQIDG 669
Query: 70 SKSEMQVK-EQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTH 128
++EM K E + +IT + L+LE +SKL+ + E+
Sbjct: 670 LQNEMSQKIETMQFEKDNLITKQNQ----LILE----ISKLKDLQQSLVNSKSEEMTLQI 721
Query: 129 DEESGENPMLKHQD--------SVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKL 180
+E E +L+ ++ V ++Q++ E+ E E + D F ++ + +
Sbjct: 722 NELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN--DLQEKFAQLEAENSI 779
Query: 181 QMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKK----------------Q 224
++++KK + +T + + SKSK + EK+ Q
Sbjct: 780 -LKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQ 838
Query: 225 INSGVERHK-TFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLR 283
+N +E+ + TF K +++ + L EE L + + + + K K+ +++L
Sbjct: 839 LNEEIEKQRNTFSFAEKNFEVNYQE-LQEEYACLLKVKDDLEDSKNKQELEYKSKLKALN 897
Query: 284 GALGRRLLNDEFKTQSKSFPGPDIEQLTDA--FGRDILKDEFKTRSKSLPETDERLHSTT 341
L + +N S D + + G + KD + K E+L +
Sbjct: 898 EELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQ 957
Query: 342 ERGTINDAIKTQLKRKSYPETVLKHLK 368
+++ +K + S+ +K LK
Sbjct: 958 RLSDLSEQLKQKHGEISFLNEEVKSLK 984
Score = 29.6 bits (65), Expect = 8.8
Identities = 78/415 (18%), Positives = 157/415 (37%), Gaps = 73/415 (17%)
Query: 12 KSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSK 71
K+Q+ + P+++ K K K + S L + NE I Q S
Sbjct: 24 KAQSDGQSPSKK-------QKKKRKTSSSKHDVSAHHDLNIDQSQCNEMYINSSQRVEST 76
Query: 72 SEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVS-----------KLEMQIEKTKKLP 120
+ RTL I +H E G ++ LE + S + M+ K L
Sbjct: 77 VIPESTIMRTLHSGEITSH--EQGFSVELESEISTTADDCSSEVNGCSFVMRTGKPTNLL 134
Query: 121 REKRHSTHDE-------------ESGENPMLKHQDSVSKIQVQLEIQETSEG-EG-RSIP 165
RE+ D E E+ + Q + ++ +LE + G EG + +
Sbjct: 135 REEEFGVDDSYSEQGAQDSPTHLEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQ 194
Query: 166 DKNSMFVHQDSV-----SKLQMQEKKKITPGRE-----RRNTRIVVPNENV-------IS 208
+ + +D + + LQ ++K RE ++ ++ + + + S
Sbjct: 195 EFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNS 254
Query: 209 VHQDSKSKLQMQEKKQINSGVER-----HKTFPLEIKKKDISLEHLLPEEKVLLSRSESQ 263
H + + L +Q K+QI + ++ H + KK+D +++ +EK+ + E Q
Sbjct: 255 THSSTAADL-LQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEME-Q 312
Query: 264 TKKLQ---AKVTSRKKTDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLTDAFGRDILK 320
KK++ + K+T IE L +++ +E KT ++L I++
Sbjct: 313 DKKVENSNKEEIQEKETIIEE----LNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 368
Query: 321 --DEFKTRSKSLPETDERLHSTTER-----GTINDAIKTQLKRKSYPETVLKHLK 368
E K L + ++ ++E GT+ + K K + +++ ++
Sbjct: 369 KNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 53.9 bits (128), Expect = 4e-07
Identities = 94/451 (20%), Positives = 180/451 (39%), Gaps = 60/451 (13%)
Query: 34 KTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRTLKGQRIITHDEE 93
K LQ + ++ E + + I + ++++ + LK + I E
Sbjct: 523 KCALQRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAE--IVSASE 580
Query: 94 PGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDEESGENPMLK------HQDSVSKI 147
K L L+H+ V+ ++++E +K + + E L+ H++ +SK+
Sbjct: 581 SRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKL 640
Query: 148 QVQLEIQETSEGEGRSIPDKNSMFVH-QDSVSKLQMQEKKKITPGRERRNTRIVVPNENV 206
+ LEI+ E K+++ +H + + LQ + +KI + ++ I N+ +
Sbjct: 641 KEDLEIEHRINIEKL----KDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLI 696
Query: 207 ISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKK 266
+ + SKL+ ++ +NS E L+I + +E L EEK E + ++
Sbjct: 697 LEI-----SKLKDLQQSLVNSKSEE---MTLQINELQKEIEILRQEEKEK-GTLEQEVQE 747
Query: 267 LQAKVT------SRKKTDIESLRGALGRR--LLNDEFKTQSKSFPGPDIEQLTDAFGRDI 318
LQ K K+ D++ L +L DE KT I R I
Sbjct: 748 LQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLK---IHTPVSQEERLI 804
Query: 319 LKDEFKTRSKS---------LPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKG 369
D K++SK L E +E L + +N+ I+ Q S+ E +
Sbjct: 805 FLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQ--LNEEIEKQRNTFSFAEKNFE---- 858
Query: 370 VNGKDIIKH---LINIQSKSHGETDKNFFAYATGRGLMKES--------TTTQLKSHP-E 417
VN +++ + L+ ++ +K Y + + E TT ++KS +
Sbjct: 859 VNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFD 918
Query: 418 TDKEFLADAIGRGIIIGPITTQLKSHRETDK 448
DK F+A+ + G ++ TT+L E K
Sbjct: 919 EDKTFVAETLEMGEVVEKDTTELMEKLEVTK 949
Score = 40.4 bits (93), Expect = 0.005
Identities = 58/278 (20%), Positives = 116/278 (41%), Gaps = 49/278 (17%)
Query: 27 EHQESLSKTKLQIKKQETSTEQPL--------TTPDKEPNENLILRHQDSM-SKSEMQVK 77
E Q +L K K ++ + E ++ L + + NL+L Q + ++S+ +++
Sbjct: 3211 ELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIE 3270
Query: 78 EQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKR-HSTHDEESG--- 133
QR L ++ EE G+NL L+ K+ ++ E + L RE+ H+ G
Sbjct: 3271 SQRMLYDAQL---SEEQGRNLELQVLLESEKVRIR-EMSSTLDRERELHAQLQSSDGTGQ 3326
Query: 134 ENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRE 193
P L +D + ++Q QLE + + E + +K + DS+ Q EK +
Sbjct: 3327 SRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKL----DSLQTRQQMEKDR------ 3376
Query: 194 RRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEE 253
Q + LQ +++ + H E++ K L+ L E+
Sbjct: 3377 -----------------QVHRKTLQTEQEANTEGQKKMH-----ELQSKVEDLQRQLEEK 3414
Query: 254 KVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLL 291
+ + + + + ++LQ + +K ++E RR+L
Sbjct: 3415 RQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRIL 3452
Score = 40.0 bits (92), Expect = 0.006
Identities = 67/318 (21%), Positives = 132/318 (41%), Gaps = 60/318 (18%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQ--IKKQETSTEQPLTT---PDKEP 57
E+Q Q EK + E+L V+ Q + LQ +K E E+ ++ ++E
Sbjct: 1991 EQQLLQETEK------LMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEK 2044
Query: 58 NENLILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTK 117
N L+ Q + + + K ++ L Q I D E +++ Q + KLE Q++
Sbjct: 2045 NTELMDLRQQNQALEKQLEKMRKFLDEQAI---DREHERDVF---QQEIQKLEQQLKVVP 2098
Query: 118 KLPREKRHSTHDEESGENPMLKHQDS-----VSKIQVQLEIQETSEGEGRSIPDKNSMFV 172
+ H T + E N + + D +SK Q+Q +IQE +E
Sbjct: 2099 RFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNE-------------- 2144
Query: 173 HQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQ----------EK 222
+ KL+ + RE +V ++ +V + L++Q ++
Sbjct: 2145 ---EIEKLEFRV-------RELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKE 2194
Query: 223 KQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESL 282
K+I + E+ + F E++ K+ ++ L + ++ S ++ ++L+ + K D+E L
Sbjct: 2195 KEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQE-NKLFKDDMEKL 2253
Query: 283 RGALGRRLLNDEFKTQSK 300
A+ +D TQ +
Sbjct: 2254 GLAIKE---SDAMSTQDQ 2268
Score = 37.4 bits (85), Expect = 0.042
Identities = 65/298 (21%), Positives = 124/298 (41%), Gaps = 40/298 (13%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI 62
E+Q A E+ V E +Q L++ +K++ S E+ + P E + N+
Sbjct: 2391 EQQVETANEEMTFMKNVLKETNFKMNQ--LTQELFSLKRERESVEKIQSIP--ENSVNVA 2446
Query: 63 LRHQDSMSKSEMQV----KEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIE-KTK 117
+ H S K E++V ++L+ Q EE GK ++ + + +LE + K
Sbjct: 2447 IDHL-SKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDL 2505
Query: 118 KLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSV 177
+L + + +E G+ Q + +Q +E + + V Q +
Sbjct: 2506 ELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAA------------LVSQIQL 2553
Query: 178 SKLQ-----MQEKKKITPGRERRNTRIVVPNENVISVHQDSK----SKLQMQEKKQINSG 228
+Q Q+ + I+ ER N +N+ + +D S L ++ + +
Sbjct: 2554 EAVQEYAKFCQDNQTISSEPERTNI------QNLNQLREDELGSDISALTLRISELESQV 2607
Query: 229 VERHKTFPLEIKKKDISLEHLLPEEKVLLSRS---ESQTKKLQAKVTSRKKTDIESLR 283
VE H + LE ++ +I+ +++L +EK LL E KK + K R D+E L+
Sbjct: 2608 VEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLK 2665
Score = 35.0 bits (79), Expect = 0.21
Identities = 74/387 (19%), Positives = 150/387 (38%), Gaps = 45/387 (11%)
Query: 10 AEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSM 69
AE +A E +L+ H+E LSK K++ E + + N + + Q
Sbjct: 615 AESQEAELERLRTQLLFSHEEELSKL-----KEDLEIEHRINIEKLKDNLGIHYKQQIDG 669
Query: 70 SKSEMQVK-EQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTH 128
++EM K E + +IT + L+LE +SKL+ + E+
Sbjct: 670 LQNEMSQKIETMQFEKDNLITKQNQ----LILE----ISKLKDLQQSLVNSKSEEMTLQI 721
Query: 129 DEESGENPMLKHQD--------SVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKL 180
+E E +L+ ++ V ++Q++ E+ E E + D F ++ + +
Sbjct: 722 NELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN--DLQEKFAQLEAENSI 779
Query: 181 QMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKK----------------Q 224
++++KK + +T + + SKSK + EK+ Q
Sbjct: 780 -LKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQ 838
Query: 225 INSGVERHK-TFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLR 283
+N +E+ + TF K +++ + L EE L + + + + K K+ +++L
Sbjct: 839 LNEEIEKQRNTFSFAEKNFEVNYQE-LQEEYACLLKVKDDLEDSKNKQELEYKSKLKALN 897
Query: 284 GALGRRLLNDEFKTQSKSFPGPDIEQLTDA--FGRDILKDEFKTRSKSLPETDERLHSTT 341
L + +N S D + + G + KD + K E+L +
Sbjct: 898 EELHLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEKLEVTKREKLELSQ 957
Query: 342 ERGTINDAIKTQLKRKSYPETVLKHLK 368
+++ +K + S+ +K LK
Sbjct: 958 RLSDLSEQLKQKHGEISFLNEEVKSLK 984
Score = 29.6 bits (65), Expect = 8.8
Identities = 78/415 (18%), Positives = 157/415 (37%), Gaps = 73/415 (17%)
Query: 12 KSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSK 71
K+Q+ + P+++ K K K + S L + NE I Q S
Sbjct: 24 KAQSDGQSPSKK-------QKKKRKTSSSKHDVSAHHDLNIDQSQCNEMYINSSQRVEST 76
Query: 72 SEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVS-----------KLEMQIEKTKKLP 120
+ RTL I +H E G ++ LE + S + M+ K L
Sbjct: 77 VIPESTIMRTLHSGEITSH--EQGFSVELESEISTTADDCSSEVNGCSFVMRTGKPTNLL 134
Query: 121 REKRHSTHDE-------------ESGENPMLKHQDSVSKIQVQLEIQETSEG-EG-RSIP 165
RE+ D E E+ + Q + ++ +LE + G EG + +
Sbjct: 135 REEEFGVDDSYSEQGAQDSPTHLEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQ 194
Query: 166 DKNSMFVHQDSV-----SKLQMQEKKKITPGRE-----RRNTRIVVPNENV-------IS 208
+ + +D + + LQ ++K RE ++ ++ + + + S
Sbjct: 195 EFEAAIKQRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNS 254
Query: 209 VHQDSKSKLQMQEKKQINSGVER-----HKTFPLEIKKKDISLEHLLPEEKVLLSRSESQ 263
H + + L +Q K+QI + ++ H + KK+D +++ +EK+ + E Q
Sbjct: 255 THSSTAADL-LQAKQQILTHQQQLEEQDHLLEDYQKKKEDFTMQISFLQEKIKVYEME-Q 312
Query: 264 TKKLQ---AKVTSRKKTDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLTDAFGRDILK 320
KK++ + K+T IE L +++ +E KT ++L I++
Sbjct: 313 DKKVENSNKEEIQEKETIIEE----LNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQ 368
Query: 321 --DEFKTRSKSLPETDERLHSTTER-----GTINDAIKTQLKRKSYPETVLKHLK 368
E K L + ++ ++E GT+ + K K + +++ ++
Sbjct: 369 KNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 53.1 bits (126), Expect = 7e-07
Identities = 79/373 (21%), Positives = 159/373 (42%), Gaps = 41/373 (10%)
Query: 3 EEQTYQAAEKSQA-HNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENL 61
E++ + ++K + NE+ E+ +++ ++LSK ++ K Q T + L + E +
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE-NSERQIKI 555
Query: 62 ILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNL---VLEHQDSVSKLEM---QIEK 115
+ + + ++++ ++++ + + + E+ K L + E +SK+E QI+K
Sbjct: 556 LEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615
Query: 116 TKKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEI---------QETSEGEGRSIPD 166
+ +EK + E+ + + K + + K L+I QE SE E +
Sbjct: 616 ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKL 675
Query: 167 KNSMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQ------ 220
K ++ ++ +L+ EK+ E R NV S+ S Q+Q
Sbjct: 676 KKTLDSFKNLTFQLESLEKENSQLDEENLELR-----RNVESLKCASMKMAQLQLENKEL 730
Query: 221 --EKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTD 278
EK+Q+ G+E K + ++ ++S + L E + L E+ KK+Q + D
Sbjct: 731 ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ--LESELQD 788
Query: 279 IESLRGALGRRLLNDEFKTQSKSF-----PGPDIEQLTDAFGRDILKDEFKTRSKSLPET 333
+E L + L +E K SK +EQ T +D K + + +K L +
Sbjct: 789 LEMENQTLQKNL--EELKISSKRLEQLEKENKSLEQETSQLEKD--KKQLEKENKRLRQQ 844
Query: 334 DERLHSTTERGTI 346
E +T E +
Sbjct: 845 AEIKDTTLEENNV 857
Score = 37.7 bits (86), Expect = 0.032
Identities = 58/291 (19%), Positives = 127/291 (43%), Gaps = 30/291 (10%)
Query: 13 SQAHNEVPNERLVVEHQES-LSKTKLQIKKQETSTEQPLTTPDKEPNENLI----LRHQD 67
S+ ++ E +E + S L K K Q++K+ Q D EN + L ++
Sbjct: 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN 866
Query: 68 SMSKSEMQVKEQRTLKGQRIITHDEE-------PGKNLVLEHQDSVSK----------LE 110
E+ + ++ ++ + + ++E K LV +D VS+ LE
Sbjct: 867 KTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Query: 111 MQIEKTKKLPREKRHSTHDEESGENPMLKHQDS--VSKIQVQLEIQETSEGEGRSIPDKN 168
+ +K+ K HDE+S ++ K +S S ++ LEI+E + +++
Sbjct: 927 KLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEES 986
Query: 169 SMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSG 228
+ + Q + + KK ++R++ +V + IS +D+K + + QE +
Sbjct: 987 TNYNQQ--LRQELKTVKKNYEALKQRQDEERMVQSSPPIS-GEDNKWERESQETTR---E 1040
Query: 229 VERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDI 279
+ + K +E+++ + +L+ K L + E+Q LQA++ + ++ +
Sbjct: 1041 LLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTV 1091
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 53.1 bits (126), Expect = 7e-07
Identities = 79/373 (21%), Positives = 159/373 (42%), Gaps = 41/373 (10%)
Query: 3 EEQTYQAAEKSQA-HNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENL 61
E++ + ++K + NE+ E+ +++ ++LSK ++ K Q T + L + E +
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE-NSERQIKI 555
Query: 62 ILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNL---VLEHQDSVSKLEM---QIEK 115
+ + + ++++ ++++ + + + E+ K L + E +SK+E QI+K
Sbjct: 556 LEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615
Query: 116 TKKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEI---------QETSEGEGRSIPD 166
+ +EK + E+ + + K + + K L+I QE SE E +
Sbjct: 616 ELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKL 675
Query: 167 KNSMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQ------ 220
K ++ ++ +L+ EK+ E R NV S+ S Q+Q
Sbjct: 676 KKTLDSFKNLTFQLESLEKENSQLDEENLELR-----RNVESLKCASMKMAQLQLENKEL 730
Query: 221 --EKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTD 278
EK+Q+ G+E K + ++ ++S + L E + L E+ KK+Q + D
Sbjct: 731 ESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ--LESELQD 788
Query: 279 IESLRGALGRRLLNDEFKTQSKSF-----PGPDIEQLTDAFGRDILKDEFKTRSKSLPET 333
+E L + L +E K SK +EQ T +D K + + +K L +
Sbjct: 789 LEMENQTLQKNL--EELKISSKRLEQLEKENKSLEQETSQLEKD--KKQLEKENKRLRQQ 844
Query: 334 DERLHSTTERGTI 346
E +T E +
Sbjct: 845 AEIKDTTLEENNV 857
Score = 35.8 bits (81), Expect = 0.12
Identities = 53/302 (17%), Positives = 124/302 (41%), Gaps = 53/302 (17%)
Query: 13 SQAHNEVPNERLVVEHQES-LSKTKLQIKKQETSTEQPLTTPDKEPNENLI----LRHQD 67
S+ ++ E +E + S L K K Q++K+ Q D EN + L ++
Sbjct: 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN 866
Query: 68 SMSKSEMQVKEQRTLKGQRIITHDEE-------PGKNLVLEHQDSVSK----------LE 110
E+ + ++ ++ + + ++E K LV +D VS+ LE
Sbjct: 867 KTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Query: 111 MQIEKTKKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSM 170
+ +K+ K HDE+S ++ +++ SK++ L K S+
Sbjct: 927 KLTHELEKIGLNKERLLHDEQSTDD---RYKLLESKLESTL---------------KKSL 968
Query: 171 FVHQDSVSKLQMQEKKKITPGRE-RRNTRIVVPNENVISVHQDSKSKLQM---------- 219
+ ++ ++ L+ + ++ ++ R+ + V N + QD + +Q
Sbjct: 969 EIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNK 1028
Query: 220 --QEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKT 277
+E ++ + + K +E+++ + +L+ K L + E+Q LQA++ + ++
Sbjct: 1029 WERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Query: 278 DI 279
+
Sbjct: 1089 TV 1090
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 52.0 bits (123), Expect = 2e-06
Identities = 76/351 (21%), Positives = 136/351 (38%), Gaps = 37/351 (10%)
Query: 10 AEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSM 69
AEK Q E E V +E+ + + K+Q++ E+ + + N ++ Q+ M
Sbjct: 349 AEKEQEEEEQKQEMEVKMEEET--EVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVM 406
Query: 70 SKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHD 129
+ ++ E + + + EP +E L E L EK +
Sbjct: 407 ETNRVESVEPSENEASKEL----EPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKE 462
Query: 130 EESGE---NPMLKHQ-DSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQ-- 183
E+ E P+ + Q S ++Q+Q + Q + + S P+ S+ V Q + Q Q
Sbjct: 463 EKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGH 522
Query: 184 --EKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKK 241
++K P + T VP E V++VH +SKSK + + + + G R+KT +
Sbjct: 523 LLPERKDFPVESVKLTE--VPVEPVLTVHPESKSKTKTRSRSR---GRARNKTSKSRSRS 577
Query: 242 KDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSKS 301
S S S S + ++ +S T S R + + E +++S+
Sbjct: 578 SSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSR- 636
Query: 302 FPGPDIEQLTDAFGRDILKDEFKTRSKSLPETD----ERLHSTTERGTIND 348
GR +D RS D ER H +++ G+ D
Sbjct: 637 -------------GRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRD 674
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 51.6 bits (122), Expect = 2e-06
Identities = 47/265 (17%), Positives = 118/265 (44%), Gaps = 9/265 (3%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI 62
E+Q + + Q + ER E QE + + + ++QE EQ L +E E +
Sbjct: 294 EQQQQRLRREQQLRRKQEEERR--EQQEERREQQERREQQEERREQQLRREQEERREQQL 351
Query: 63 LRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPRE 122
R Q+ + + +EQ + ++ + +++ + L + + + E Q+ + ++L RE
Sbjct: 352 RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR-EQQLRREQQLRRE 410
Query: 123 KRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQM 182
++ + E + + Q+ + Q QE E + ++ ++ ++ ++
Sbjct: 411 QQLRREQQLRREQQLRREQE--EERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
Query: 183 QEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKK 242
QE++K R++ R E + + ++ + + Q + ++Q+ E + L+ +++
Sbjct: 469 QERRKQQLKRDQEEER----RERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524
Query: 243 DISLEHLLPEEKVLLSRSESQTKKL 267
+ L+ L E+ L E + ++L
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQL 549
Score = 47.0 bits (110), Expect = 5e-05
Identities = 63/284 (22%), Positives = 125/284 (44%), Gaps = 37/284 (13%)
Query: 7 YQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQ 66
+QA EKS+ + + R + Q + Q++ +E + P++E E R Q
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQR-----ERQLRAEERQQREQRFLPEEEEKEQR--RRQ 823
Query: 67 DSMSKSEMQVKE-----QRTLKGQRIITHDEEPGKNLVLEHQDSVS-----KLEMQIEKT 116
+ E+Q E QR + Q++ +EE G E + S K Q+E+
Sbjct: 824 RREREKELQFLEEEEQLQRRERAQQL--QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEE 881
Query: 117 KKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDS 176
+K +RH+ + + + + + K Q + + + +L+ +E E R ++ + ++
Sbjct: 882 RK---RRRHTLYAKPALQEQLRKEQQLLQEEEEELQREER---EKRRRQEQERQYREEE- 934
Query: 177 VSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFP 236
+LQ +E++ + RE+R + E +D K +Q+K++ G E K
Sbjct: 935 --QLQQEEEQLLREEREKRRRQ-----ERERQYRKDKK----LQQKEEQLLGEEPEKRRR 983
Query: 237 LEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIE 280
E +KK E L EE+ LL + ++ + + RKK +++
Sbjct: 984 QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQ 1027
Score = 43.5 bits (101), Expect = 6e-04
Identities = 52/289 (17%), Positives = 122/289 (42%), Gaps = 25/289 (8%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI 62
EE+ Q E+ E R ++ KLQ K+++ E+P +E +
Sbjct: 932 EEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY- 990
Query: 63 LRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPRE 122
R ++ + + E Q+ + K +R + K+ + + ++ + + E EK + RE
Sbjct: 991 -REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER--EKRRLQERE 1047
Query: 123 KRHSTHDEESGENPML--------KHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQ 174
+++ +E E L + Q+ + + + E+Q+ E R P+K +
Sbjct: 1048 RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE 1107
Query: 175 DSV---SKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVER 231
+LQ +E++ + RE+R + + ++Q +E++ + E+
Sbjct: 1108 RQCREEEELQQEEEQLLREEREKR-------RRQELERQYREEEEVQQEEEQLLREEPEK 1160
Query: 232 HKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIE 280
+ LE + ++ E L +E+ L R E + ++ + + R++ +++
Sbjct: 1161 RRRQELERQYRE---EEELQQEEEQLLREEQEKRRQERERQYREEEELQ 1206
Score = 43.1 bits (100), Expect = 8e-04
Identities = 59/288 (20%), Positives = 115/288 (39%), Gaps = 22/288 (7%)
Query: 1 MTEEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNEN 60
+ EE+ QA E+ ++ +L E SK + +KQE + + E+
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 61 LILRHQDSMSKSEMQVKEQ-RTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKL 119
+ ++ + + Q +EQ R Q E G+ + + E Q+ ++
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ 804
Query: 120 PREKRHSTHDEE-----------SGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKN 168
RE+R +EE E L+ ++ + + + ++QE +G +
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 169 SMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSG 228
S +D + Q++E++K RR+T P Q K + +QE+++
Sbjct: 865 SQEQRRDQKWRWQLEEERK-----RRRHTLYAKP----ALQEQLRKEQQLLQEEEEELQR 915
Query: 229 VERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKK 276
ER K E +++ E L EE+ LL R E + ++ Q + +K
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLL-REEREKRRRQERERQYRK 962
Score = 42.7 bits (99), Expect = 0.001
Identities = 51/294 (17%), Positives = 123/294 (41%), Gaps = 16/294 (5%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTK-LQIKKQETSTEQPLTTPDKEPNENL 61
EEQ Q E+ Q H + + + + E Q+ + + + ++QE +++P +E +
Sbjct: 1466 EEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525
Query: 62 ILRHQDSMSKSEMQVK-----EQRTLKGQRIITHDE---EPGKNLVLEHQDSVSKLEMQI 113
+ Q + E Q++ +QR R +E + + L Q+ K ++
Sbjct: 1526 RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Query: 114 EKTKKLPREKRHSTHDE----ESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNS 169
+K ++ +E++ ++ + G+ + + +D + QL +QE E +
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL-LQEREEQQLHRQERDRK 1644
Query: 170 MFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGV 229
+ + + + +++ + R+ R ++ + + + + +E++Q+
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQE 1704
Query: 230 ERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLR 283
K E + + LE EE+ L R E++ ++L+ + RK + E LR
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQL--RQETEQEQLRRQERYRKILEEEQLR 1756
Score = 38.5 bits (88), Expect = 0.019
Identities = 52/298 (17%), Positives = 119/298 (39%), Gaps = 35/298 (11%)
Query: 1 MTEEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNEN 60
+ EEQ + E+ Q + + + E Q + + Q+ +QE + L E
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRL--------EE 1585
Query: 61 LILRHQDSMSKSEMQVKEQRTLKGQRIITHDEE----PGKNLVLEHQDSVSKLEMQIEKT 116
+R Q+ K ++ R +GQ+ + + + + L+ E ++ +L Q
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREE--QQLHRQERDR 1643
Query: 117 KKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDS 176
K L E + + E L+H D K + + ++ + E + +++ F ++
Sbjct: 1644 KFLEEEPQLRRQEREQ----QLRH-DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 177 VSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFP 236
+ Q +E+K + ++ R + + + +E++Q+ E+ +
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQEL----------------ERKFREEEQLRQETEQEQLRR 1742
Query: 237 LEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDE 294
E +K + E L PE + R + + +K + + R++ + + LR R +E
Sbjct: 1743 QERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Score = 35.8 bits (81), Expect = 0.12
Identities = 53/337 (15%), Positives = 135/337 (40%), Gaps = 38/337 (11%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI 62
EE+ Q ++ + E + L E QE + +L+ ++QE ++ ++E E +
Sbjct: 613 EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRL 672
Query: 63 LRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPRE 122
R + + + +E++ +RI + + K + Q+E +
Sbjct: 673 KREHEEERREQELAEEEQEQARERI---------------KSRIPKWQWQLESEADARQS 717
Query: 123 KRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQM 182
K +S ++ G+ + ++ + + +L+ QE E R+ + +D + Q
Sbjct: 718 KVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE----EERAHRQQQEEEQRRDFTWQWQA 773
Query: 183 QEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKK 242
+EK + GR+R + R + + + + + + + + + +R + + +++
Sbjct: 774 EEKSE--RGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR----QRRER 827
Query: 243 DISLEHLLPEEKVLLSRSESQTKKLQ--AKVTSRKKTDIESLRGALGRRLLNDEFKTQSK 300
+ L+ L EE++ Q ++ + + ++ E R R L +E K +
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 301 SFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERL 337
+ + + L+++ + + L E +E L
Sbjct: 888 TL-----------YAKPALQEQLRKEQQLLQEEEEEL 913
Score = 35.4 bits (80), Expect = 0.16
Identities = 39/208 (18%), Positives = 92/208 (44%), Gaps = 22/208 (10%)
Query: 27 EHQESLSKTKLQIKK-QETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRTLKGQ 85
E +E + + Q+++ QE EQ L ++E LR SE Q++ ++ + +
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR-------SEQQLRREQEERRE 547
Query: 86 RIITHDEEPGKNLVLEHQDSVSKLEM-----QIEKTKKLPREKRHSTHDEESGENPMLKH 140
+++ +EE K L E ++ K E Q+ K ++ R++R EE E + +
Sbjct: 548 QLLKREEE--KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605
Query: 141 Q----DSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRERRN 196
+ + + + +L+ +E E + + + + + QE+++ RE
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 197 TRIVVPNENVISVHQDSKSKLQMQEKKQ 224
R+ + + H++ + + ++ E++Q
Sbjct: 666 ERL---EQRLKREHEEERREQELAEEEQ 690
Score = 34.3 bits (77), Expect = 0.36
Identities = 47/280 (16%), Positives = 118/280 (42%), Gaps = 22/280 (7%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI 62
EEQ+ + Q + +E L + QE + + + ++++ + + T ++ P+E +
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET-EEFPDEEQL 210
Query: 63 LRHQ--DSMSKSEMQVKEQRTLKGQRIITHDEE------------PGKNLVLEHQDSVSK 108
R + + K + ++QR + R+ +EE + L E +
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 109 LEMQIEKTKKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKN 168
L+ + E+ +KL R++ EE + L+ + + + Q + E +E E +
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE-ERREQQEERREQQERRE 329
Query: 169 SMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSG 228
++ + + +E+++ RE+ R + + ++ + + Q++ ++Q+
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEER---REQQLRREQEEERREQQLRREQQLRRE 386
Query: 229 VERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQ 268
+ + L +++ + E L E+ L R E Q ++ Q
Sbjct: 387 QQLRREQQLR-REQQLRREQQLRREQQL--RREQQLRREQ 423
Score = 33.9 bits (76), Expect = 0.46
Identities = 31/150 (20%), Positives = 68/150 (45%), Gaps = 7/150 (4%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI 62
EEQ Q E+ Q + +++ E Q + + Q+++QE + ++ E
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 63 LRHQDSMSK--SEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQI--EKTKK 118
LR Q+S K E Q++++R ++ + + GK E Q + + E ++ E+ ++
Sbjct: 1788 LRSQESDRKFREEEQLRQERE---EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Query: 119 LPREKRHSTHDEESGENPMLKHQDSVSKIQ 148
E++ +T ++ E L ++ + Q
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQ 1874
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 51.2 bits (121), Expect = 3e-06
Identities = 108/545 (19%), Positives = 218/545 (40%), Gaps = 103/545 (18%)
Query: 11 EKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMS 70
EKS+ E+ + + + E+LSK+K I++ + E + + + L H +M
Sbjct: 1224 EKSELKMEIDD---MASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQ 1280
Query: 71 KSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDE 130
K+ +Q T G+ ++H E ++L+ + S L Q+E+ K R+ T +
Sbjct: 1281 KARLQ-----TQNGE--LSHRVEEKESLISQLTKSKQALTQQLEELK---RQMEEETKAK 1330
Query: 131 ESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQ-------DSVSKLQMQ 183
+ + + + ++ Q E ++ ++ E + K + V Q D++ + +
Sbjct: 1331 NAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEEL 1390
Query: 184 E--KKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKK 241
E KKK+ + N S+ + +K +LQ E + + +ER T + K
Sbjct: 1391 EEAKKKLAQRLQEAEENTETANSKCASL-EKTKQRLQ-GEVEDLMRDLERSHTACATLDK 1448
Query: 242 KDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSKS 301
K + + +L E K L S+++ + Q K + T++ +R A
Sbjct: 1449 KQRNFDKVLAEWKQKLDESQAELEAAQ-KESRSLSTELFKMRNA---------------- 1491
Query: 302 FPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQL---KRKS 358
E++ D + L+ E K + + + E++ T + + +A KT+ + KS
Sbjct: 1492 -----YEEVVDQL--ETLRRENKNLQEEISDLTEQIAETGK--NLQEAEKTKKLVEQEKS 1542
Query: 359 YPETVLKHLKGVNGKDIIKHLINIQSKSHGETDKNFFAYATGRGLMKESTTTQLKSHPET 418
+ L+ ++G S H E+ + L + +Q+KS E
Sbjct: 1543 DLQVALEEVEG--------------SLEHEES----------KILRVQLELSQVKS--EL 1576
Query: 419 DKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVEP 478
D++ + QLK + + E L+ + +I + +LK E D+
Sbjct: 1577 DRKVIEK--------DEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNE 1628
Query: 479 LTNAIG-SSKTIGEIKTQLRT----------HYDVNLFKNKDMS-----VQRQEGIFTRS 522
+ +G S++ + E + LRT H D L N+D+ V+R+ G+
Sbjct: 1629 MEIQLGHSNRQMAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEE 1688
Query: 523 ITPSK 527
+ K
Sbjct: 1689 LEEMK 1693
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 50.1 bits (118), Expect = 6e-06
Identities = 65/279 (23%), Positives = 123/279 (44%), Gaps = 31/279 (11%)
Query: 25 VVEHQESLSKTKLQIKKQETSTEQPLTTPDKEP----NENLILRHQDSMSKSEMQVKEQR 80
V E + S+ ++KL IK+ + S ++ T D++ L + + ++K E +E+
Sbjct: 2106 VKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEES 2165
Query: 81 TL--KGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKL-----PREKRHSTHDEESG 133
L K +I DEE G +E ++ + L+ + K K+ P+EK S DE
Sbjct: 2166 KLARKHSEVILDDEEEGG---IEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVES 2222
Query: 134 ENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRE 193
E + +S+ +LE QE+ E ++ ++ + + +E+K+ G E
Sbjct: 2223 EEHFSEEMESLLD---ELEKQESLSSEEEE--EREEEEEREEEEVREEEEERKEEEEGEE 2277
Query: 194 RRNTRIVVPNENVISVHQDSKSKLQMQEKKQ-------INSGVERHKTFPLEIKKKDISL 246
++ V E + K K ++QEK++ I S E E +++ SL
Sbjct: 2278 KQ----VEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSL 2333
Query: 247 EHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIES-LRG 284
E + EK +L + + + Q + + R + + S LRG
Sbjct: 2334 EEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSILRG 2372
Score = 42.4 bits (98), Expect = 0.001
Identities = 77/401 (19%), Positives = 170/401 (42%), Gaps = 59/401 (14%)
Query: 10 AEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQP---LTTPDKE---------- 56
AEK +A E R + + +E L++ + Q+ ++E Q +T D+E
Sbjct: 1584 AEKKRAQEE----RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQ 1639
Query: 57 PNENLILRHQDSMSKSEMQVKEQRTL--KGQRIITHDEEPGKNLVLEHQDSVSKLEMQIE 114
E L R + ++E ++++ L K +++ +E+ K + + +
Sbjct: 1640 KEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAK----KGGKLAEVKNILAQ 1695
Query: 115 KTKKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQ 174
K ++LP+ +++ E+ + + + + ++ + E E ++ EG+ + +K + +
Sbjct: 1696 KVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEE--ELNQEEGKLVEEKKKLAEEE 1753
Query: 175 DSVS-----------------KLQMQEKKKITPGRER---RNTRIVVPNENVISVHQDSK 214
++++ +L +QEK+K+ +E+ R+ E +I + K
Sbjct: 1754 EALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLI----EKK 1809
Query: 215 SKLQMQEKKQINSGVERHKTFPLEIKKKDISLE--HLLPEEKVLLSRSESQTKKLQAKVT 272
KL + ++ INS E K + +KK+++ E +L E++ L R E+ +
Sbjct: 1810 MKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKERLTH 1869
Query: 273 SRKK-TDIESLRGALGRRLLNDEFK-TQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSL 330
S+K+ +++ G + L E K TQ K E+L + + + ++ SL
Sbjct: 1870 SKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVED------SL 1923
Query: 331 PETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKGVN 371
+ E+L + + A+ KR + K K +N
Sbjct: 1924 AKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALN 1964
Score = 39.7 bits (91), Expect = 0.008
Identities = 48/232 (20%), Positives = 102/232 (43%), Gaps = 34/232 (14%)
Query: 17 NEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQV 76
+EV +E E ESL +++KQE+ L++ ++E E R ++ + + E +
Sbjct: 2218 DEVESEEHFSEEMESLLD---ELEKQES-----LSSEEEEEREEEEEREEEEVREEEEER 2269
Query: 77 KEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDEESGENP 136
KE+ + +++ +EE K + ++ V + E E+ +++ E+ + +E E
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEE 2329
Query: 137 MLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRERRN 196
++ V D+ + ++ KLQ Q +K + GRER
Sbjct: 2330 SCSLEEEV---------------------DREKEILKKEKQFKLQEQRRKSLR-GRERVL 2367
Query: 197 TRI-VVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLE 247
+ + VP+ ++ L+ KK +++ +E + P+ + +K IS E
Sbjct: 2368 SILRGVPHGKGRAIR---LGVLKSPLKKLMSTALEMKEKTPVPVPEKQISWE 2416
Score = 31.6 bits (70), Expect = 2.3
Identities = 45/263 (17%), Positives = 100/263 (38%), Gaps = 36/263 (13%)
Query: 40 KKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLV 99
+KQET E +EP ++L+ M +++Q+ + ++ +NL
Sbjct: 994 QKQETFREMQQQMIGEEPLDHLL-----GMRATDLQILSTQV---------EQRLNENLT 1039
Query: 100 LEHQDSVSKLEMQIEKTKKLPREKRHSTHDEES------------GENPMLKHQDSVSKI 147
L H+D + + +L + T EES G+ + KH +
Sbjct: 1040 LSHRDEKPAFSLDVSMPSELKSSLKPPTVSEESEVAIKPSKGQRRGQAGVKKHSQKWLR- 1098
Query: 148 QVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVI 207
+++T E + + + + + + ++ ++ + +T ++ +++V
Sbjct: 1099 ----GLKKTKERDSKQMSTEPGLLEDESGTEAAPIEMEEASVYSQWSSSTSVIKLSKDVD 1154
Query: 208 SVHQD-SKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKK 266
S +D SK + + K+ +R K + KK +H ++ + E+
Sbjct: 1155 SQEKDISKDHIALTLKRLQKIRDKRDKKATAQKLKK----KHKKKGKEAKVINEETTPPV 1210
Query: 267 LQAKVTSRKKTDIESLRGALGRR 289
++ VT + K G GRR
Sbjct: 1211 MEQPVTKKVKIQGRGASGISGRR 1233
Score = 31.6 bits (70), Expect = 2.3
Identities = 28/129 (21%), Positives = 53/129 (41%), Gaps = 22/129 (17%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI 62
EE+ + E+ + E E+ V + +E K K + KK+E + E +
Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEV-----------QEKEEVF 2306
Query: 63 LRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPRE 122
++ MS+ E + ++ +EE ++ LE + K ++ EK KL +
Sbjct: 2307 EEKEEIMSEEETE-----------SLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ 2355
Query: 123 KRHSTHDEE 131
+R S E
Sbjct: 2356 RRKSLRGRE 2364
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 50.1 bits (118), Expect = 6e-06
Identities = 96/522 (18%), Positives = 213/522 (40%), Gaps = 78/522 (14%)
Query: 3 EEQTYQAA--EKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNEN 60
E +T++A E Q H++ E + E E + K ++K + + E + NE
Sbjct: 1179 EAKTHEAQIQEMRQKHSQAVEE--LAEQLEQTKRVKANLEKAKQTLENER---GELANEV 1233
Query: 61 LIL-------RHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQI 113
+L H+ ++++Q + + +G+R+ T + L +E + L
Sbjct: 1234 KVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSD 1293
Query: 114 EKTKKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETS------------EGEG 161
K+ KL ++ S + + + L +++ K+ + ++++ E E
Sbjct: 1294 SKSSKLTKD--FSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEA 1351
Query: 162 RSIPDKNSMFVH----------QDSVSKLQMQE--KKKITPGRERRNTRIVVPNENVISV 209
+ +K +H +DSV L+ E K+K+ E + R E V +
Sbjct: 1352 KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQR---HEEKVAAY 1408
Query: 210 HQDSKSKLQMQEK-KQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLS-------RSE 261
+ K+K ++Q++ + ++ + ++KK + LL EEK + + R+E
Sbjct: 1409 DKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAE 1468
Query: 262 SQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQ------SKSFPGPDIEQLTDAFG 315
++ ++ + K S + E++ LN +F+T+ SK G + +L +
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKS-- 1526
Query: 316 RDILKDEFKTRSKSLPETDERLHSTTE---RGTIN-DAIKTQLKRKSYPETVLKHLKGVN 371
+ L+ + + L E ++ L +T + R +N A+K Q +R K
Sbjct: 1527 KRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEK--- 1583
Query: 372 GKDIIKHLINIQSKSHGETDKNFFAYATGRGLMKESTTTQLKSHPETDKEFLADAIGRGI 431
K +++ + ++++ E + A A + L E L++H ++ + +AI
Sbjct: 1584 KKQLVRQVREMEAELEDERKQRSMAVAARKKL--EMDLKDLEAHIDSANKNRDEAI---- 1637
Query: 432 IIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQE 473
QL+ + K+ +++ + I AQ K +++
Sbjct: 1638 ------KQLRKLQAQMKDCMRELDDTRASREEILAQAKENEK 1673
Score = 43.1 bits (100), Expect = 8e-04
Identities = 63/273 (23%), Positives = 122/273 (44%), Gaps = 20/273 (7%)
Query: 3 EEQTYQAAEKSQAHNEVPNERL---VVEHQESLSKTKLQIKKQETSTEQPLTTPDKE-PN 58
EE+ Q EK++ E + L + E Q +++ K+Q+ K+E + L ++E
Sbjct: 1039 EEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ 1098
Query: 59 ENLILRHQDSMSKSEMQVKE-QRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTK 117
+N+ L+ + + E Q+ E Q L+ +R + E K + + + L+ ++E T
Sbjct: 1099 KNMALK---KIRELESQISELQEDLESERASRNKAEKQKR---DLGEELEALKTELEDTL 1152
Query: 118 KLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSV 177
++ E N + K + +K + +IQE + +++ + + Q
Sbjct: 1153 DSTAAQQELRSKREQEVNILKKTLEEEAKTH-EAQIQEMRQKHSQAVEELAEQ-LEQTKR 1210
Query: 178 SKLQMQEKKKITPGR--ERRNTRIVVPNENVISVHQDSKSKLQMQE-KKQINSGVERHKT 234
K +++ K+ E N V+ S H+ K + Q+QE + + N G ER +T
Sbjct: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEG-ERVRT 1269
Query: 235 FPLEIKKKDISLEHLLPEEKVLLSRSESQTKKL 267
E+ K L+ L LLS+S+S++ KL
Sbjct: 1270 ---ELADKVTKLQVELDNVTGLLSQSDSKSSKL 1299
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 49.7 bits (117), Expect = 8e-06
Identities = 105/471 (22%), Positives = 185/471 (39%), Gaps = 80/471 (16%)
Query: 14 QAHNEVPNERLVVEHQ-ESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKS 72
Q++ V NE ++H E++ + K ++ + STE +K+ E + + M +
Sbjct: 1620 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA-----NKKETEKQLQEAEQEMEEM 1674
Query: 73 EMQVKEQRTLKGQRIITHDEEPGKNLVLEH--------------------QDSVSKLEMQ 112
+ ++++ K Q+I+ +EE + H ++ + +++M+
Sbjct: 1675 KEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKME 1734
Query: 113 IEKTKKLPREKRHSTHDEESGENPMLKHQ--DSVSKIQVQLEIQE--------TSEGEGR 162
E K + S D S E LKHQ +VSK Q LE E T EG +
Sbjct: 1735 YETLSK-KFQSLMSEKDSLSEEVQDLKHQIEGNVSK-QANLEATEKHDNQTNVTEEGT-Q 1791
Query: 163 SIPDKNSMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQM--- 219
SIP + QDS+S + P + N + S H + + LQ
Sbjct: 1792 SIPGETE---EQDSLSMSTRPTCSESVPSAKSANPAV----SKDFSSHDEINNYLQQIDQ 1844
Query: 220 ------------QEKKQINSGVERHK-TFPLEIKKKDISLEHLLPEEKVLLSRSESQTKK 266
Q+ K+ + +E K T +I KD L+ +L EE ++ Q ++
Sbjct: 1845 LKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELK-MLQEEVTKMNLLNQQIQE 1903
Query: 267 LQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLTDA-FGRDILKDEFKT 325
++VT K+T E + L RL+N + G + +TDA ++L+ E K
Sbjct: 1904 ELSRVTKLKET-AEEEKDDLEERLMNQ--LAELNGSIGNYCQDVTDAQIKNELLESEMKN 1960
Query: 326 RSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKGVNGKDIIKHLINIQSK 385
K + E +E + T +++++ RK Y E + K K K L + +
Sbjct: 1961 LKKCVSELEEEKQQLVKEKT---KVESEI-RKEYLEKIQGAQKEPGNKSHAKELQELLKE 2016
Query: 386 SHGET---DKNFFAYATGRGLMK------ESTTTQLKSHPETDKEFLADAI 427
E K+ Y ++ E T+ + E KE LA A+
Sbjct: 2017 KQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAV 2067
Score = 45.8 bits (107), Expect = 1e-04
Identities = 81/404 (20%), Positives = 171/404 (42%), Gaps = 82/404 (20%)
Query: 22 ERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRT 81
E+LVVE ++ + + +Q+++++ + ++ D + + L L + ++ ++E +
Sbjct: 58 EQLVVELKDIIRQKDVQLQQKDEALQEERKAADNKIKK-LKLHAKAKLTSLNKYIEEMKA 116
Query: 82 LKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRH---------------- 125
G + T E + + +H S ++ EM+IEK K +EK
Sbjct: 117 QGGTVLPT--EPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQ 174
Query: 126 -STHDEESGENPMLKHQ-----DSVSKIQVQLEIQETSEGEGRSIPDKNSMF-----VHQ 174
+ E E M+K Q + +S +Q QL + + + + +K++ F +H+
Sbjct: 175 PAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHE 234
Query: 175 DSVSKL--------QMQEKKKITPGRERRNTRIVVPNENVISVHQ------DSKSKLQMQ 220
D + +L +MQ+K ++ + + +V V+ + Q + ++++ Q
Sbjct: 235 DELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQ 294
Query: 221 EKKQINS---------GVERHKT------FPLEIKKKDISLEHLLPEEKVLLSRSESQTK 265
+ +Q+ + ER ++ LE+ ++ +S +L E LL + E Q
Sbjct: 295 QLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFE-QAG 353
Query: 266 KLQAKVTSR--------------KKTDIESLRGALGRRLLN--DEFKTQ-SKSFPGPDIE 308
+ QA++ SR K + I SL+ G+ L + D K Q SK + +
Sbjct: 354 QAQAELESRYSALEQKHKAEMEEKTSHILSLQ-KTGQELQSACDALKDQNSKLLQDKNEQ 412
Query: 309 QLTDAFGRDILKDEFKTRSKSLPETDERL----HSTTERGTIND 348
+ A L+D+ + +SK + + RL H T + + D
Sbjct: 413 AVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPD 456
Score = 39.3 bits (90), Expect = 0.011
Identities = 57/275 (20%), Positives = 116/275 (42%), Gaps = 48/275 (17%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSK-TKLQIKKQETSTEQPLTTPDKEPNENL 61
E Q E AH+ + E++ E+ SK K+++ + E Q + +L
Sbjct: 777 ERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSL 836
Query: 62 ILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPR 121
+S++Q KE L+G + H V E ++S+ E++I K +L
Sbjct: 837 ---------QSQLQNKESEVLEGAERVRHISSK----VEELSQALSQKELEITKMDQLLL 883
Query: 122 EKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQ 181
EK+ +Q+T E + + + + + K+
Sbjct: 884 EKKRDVET-----------------------LQQTIEEKDQQVTE-----ISFSMTEKMV 915
Query: 182 MQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKK 241
++K + G E + + + N++S +++K K Q++E +++SG++++ +
Sbjct: 916 QLNEEKFSLGVEIKTLKEQL---NLLSRAEEAK-KEQVEEDNEVSSGLKQN--YDEMSPA 969
Query: 242 KDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKK 276
IS E L E +L +E + +KLQA + +RK+
Sbjct: 970 GQISKEELQHEFDLLKKENEQRKRKLQAALINRKE 1004
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 48.5 bits (114), Expect = 2e-05
Identities = 47/201 (23%), Positives = 93/201 (46%), Gaps = 28/201 (13%)
Query: 91 DEEPGKNLVLEHQDSVSKLEMQIEKT---KKLPREKRH--------STHDEESGENPMLK 139
+E+P L+ E Q+ +++L+ Q+EK ++ REKR +EE GE
Sbjct: 347 NEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEE---G 403
Query: 140 HQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRER----- 194
++ K E QE E E R+I + +S+ V ++ + L+ +EKK RE+
Sbjct: 404 EEEGDDKDDYWREQQEKLEIEKRAIVEDHSL-VAEEKMRLLKEKEKKMEDLRREKDAAEM 462
Query: 195 -------RNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLE 247
++++V +N++ H + + K+ Q++++I R + +++ +D
Sbjct: 463 LGAKIKAMESKLLVGGKNIVD-HTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETL 521
Query: 248 HLLPEEKVLLSRSESQTKKLQ 268
L L + +TKKL+
Sbjct: 522 ELKETYSSLQQEVDIKTKKLK 542
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/281 (18%), Positives = 119/281 (42%), Gaps = 9/281 (3%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETST---EQPLTTPDKEPNE 59
EE ++ EK +P ++ + QE + + + +I +QE E+ K +
Sbjct: 477 EENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ 536
Query: 60 NLILRHQDSMSKSE--MQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTK 117
+ +D M + E M+ +EQ+ + + + + + ++ + + E E+ K
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596
Query: 118 KLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSV 177
K+ E+ EE + K Q+ K+ Q E + E E + + M+ ++ +
Sbjct: 597 KMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEE--KMQEQEEKMWEQEEKMWEQEEKM 654
Query: 178 SKLQM--QEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTF 235
+ Q ++K+K+ + + + E I + + K Q QEKK + R +
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714
Query: 236 PLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKK 276
E +KK E ++ E++ + E + ++ + ++ +++
Sbjct: 715 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE 755
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 47.0 bits (110), Expect = 5e-05
Identities = 107/534 (20%), Positives = 219/534 (41%), Gaps = 90/534 (16%)
Query: 22 ERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQ-- 79
E VE + L + + ++E T +K + LR ++ + E++VK+Q
Sbjct: 778 EHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQ---LRRKEEQYRKEVEVKQQLE 834
Query: 80 ----------RTLKGQ--RIITHDEEPGKNLVLEH-----QDSVSKLEMQIEKTKKLPRE 122
RT+K +++ + + L E QD + + +K ++ ++
Sbjct: 835 LSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMAQK 894
Query: 123 KRHSTHDEESGENPMLKHQDSVSKIQV---QLEI----QETSEGEGRSIPDKNSMFVHQD 175
K +S + E L H++S+ + ++ +LEI + E E + D + +
Sbjct: 895 KMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNE 954
Query: 176 SVSKLQMQEKKKITPGRERRNTRI-VVPNENVISVHQDSKSKLQMQEKKQINSGVER-HK 233
+ K Q ++ +T + N R+ V+ EN + +SK + + Q K+++ + VE H
Sbjct: 955 DLQKTIKQNEETLTQTISQYNGRLSVLTAENAM---LNSKLENEKQSKERLEAEVESYHS 1011
Query: 234 TFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLND 293
I +D S E E ++ R+ + +LQ K+ D+ +L+ +L+
Sbjct: 1012 RLAAAIHDRDQS-ETSKRELELAFQRARDECSRLQDKM----NFDVSNLKD--NNEILSQ 1064
Query: 294 E-FKTQSKSFPGPDIEQLTDAF--GRDILKDE---FKTRSKSLPETDERLHSTTERGTIN 347
+ FKT+SK + L F RD L+++ + K L +T ++ E+ N
Sbjct: 1065 QLFKTESK------LNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQM-KEMEQKYQN 1117
Query: 348 DAIKTQLKRKSYPETVLKHLKGVNGKDII----------------KHLINIQSKSHGETD 391
+ +K K E+V + L + ++++ K +INIQ + H
Sbjct: 1118 EQVKVN-KYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQFHAIVQ 1176
Query: 392 KNFFAYATGRGLMKESTTTQLKSH----PETDKEFLADAIGRGIIIGPITTQLKSHRETD 447
K A + + L+ E +L S E ++ + R +++ + +L
Sbjct: 1177 K-LQAESEKQSLLLEERNKELISECNHLKERQYQYENEKAEREVVVRQLQQELAD--TLK 1233
Query: 448 KELLKDAIGRDIIKGPISAQLKSHQETDVEPLTNAIGSSKTIGEIKTQLRTHYD 501
K+ + +A S ++ S ++E T + K +G+I+ QL+ D
Sbjct: 1234 KQSMSEA----------SLEVTSRYRINLEDETQDL--KKKLGQIRNQLQEAQD 1275
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 46.2 bits (108), Expect = 9e-05
Identities = 79/413 (19%), Positives = 172/413 (41%), Gaps = 38/413 (9%)
Query: 8 QAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNE-NLILRHQ 66
+ ++A N E + E ++ KL+I E +Q P + + N+ L+ +
Sbjct: 50 ETVSPTRARNMKDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVE 109
Query: 67 DSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEK--TKKLPREKR 124
K E+Q +EQ +K + + E G + + ++ K Q+E TK++ ++
Sbjct: 110 VESLKRELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEK 169
Query: 125 HSTHDEESGENPMLKHQDSVS---KIQVQL-EIQETSEGE--GRSIPDKNSMFVHQDSVS 178
T + E + + +++ +L E+++ EG+ + D+ + +
Sbjct: 170 DVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEE---L 226
Query: 179 KLQMQEKKKITPGRERRNTRIVVPNENVIS--------VHQDSKSK----LQMQEKKQIN 226
KL ++ K+ + + +++ P+ENV S ++ K + QM+ +K+ N
Sbjct: 227 KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERN 286
Query: 227 SGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSE-----SQTKKLQAKVTSRKKTDIES 281
S ER + ++++K+ + E+K L R + + K + K ++IE
Sbjct: 287 SFEERIQALEEDLREKE---REIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEK 343
Query: 282 LRGAL--GRRLLNDEFKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHS 339
L A R L K Q++ F G + + T G++ L ++++ + + RL
Sbjct: 344 LSAAFAKAREALQ---KAQTQEFQGSE-DYETALSGKEALSAALRSQNLTKSTENHRLRR 399
Query: 340 TTERGTINDAIKTQLKRKSYPETVLKHLKGVNGKDIIKHLINIQSKSHGETDK 392
+ ++ T + Q + + + H + G I+ L N K E ++
Sbjct: 400 SIKKITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNE 452
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 46.2 bits (108), Expect = 9e-05
Identities = 79/413 (19%), Positives = 172/413 (41%), Gaps = 38/413 (9%)
Query: 8 QAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNE-NLILRHQ 66
+ ++A N E + E ++ KL+I E +Q P + + N+ L+ +
Sbjct: 50 ETVSPTRARNMKDFENQITELKKENFNLKLRIYFLEERMQQEFHGPTEHIYKTNIELKVE 109
Query: 67 DSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEK--TKKLPREKR 124
K E+Q +EQ +K + + E G + + ++ K Q+E TK++ ++
Sbjct: 110 VESLKRELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEK 169
Query: 125 HSTHDEESGENPMLKHQDSVS---KIQVQL-EIQETSEGE--GRSIPDKNSMFVHQDSVS 178
T + E + + +++ +L E+++ EG+ + D+ + +
Sbjct: 170 DVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEE---L 226
Query: 179 KLQMQEKKKITPGRERRNTRIVVPNENVIS--------VHQDSKSK----LQMQEKKQIN 226
KL ++ K+ + + +++ P+ENV S ++ K + QM+ +K+ N
Sbjct: 227 KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERN 286
Query: 227 SGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSE-----SQTKKLQAKVTSRKKTDIES 281
S ER + ++++K+ + E+K L R + + K + K ++IE
Sbjct: 287 SFEERIQALEEDLREKE---REIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEK 343
Query: 282 LRGAL--GRRLLNDEFKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHS 339
L A R L K Q++ F G + + T G++ L ++++ + + RL
Sbjct: 344 LSAAFAKAREALQ---KAQTQEFQGSE-DYETALSGKEALSAALRSQNLTKSTENHRLRR 399
Query: 340 TTERGTINDAIKTQLKRKSYPETVLKHLKGVNGKDIIKHLINIQSKSHGETDK 392
+ ++ T + Q + + + H + G I+ L N K E ++
Sbjct: 400 SIKKITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNE 452
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 46.2 bits (108), Expect = 9e-05
Identities = 83/395 (21%), Positives = 160/395 (40%), Gaps = 47/395 (11%)
Query: 8 QAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQD 67
Q E+ ++V RL +HQ + + + E ++ +K N + + Q
Sbjct: 682 QRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQC 741
Query: 68 SMSKSEMQVKEQRT--LKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIE-KTKKLPREKR 124
SM +++ +Q+ L G + DE L LE Q+S +L +Q E KT+ +
Sbjct: 742 SMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLE-QESNKRLLLQNELKTQAFEADNL 800
Query: 125 HSTHDEESGE-NPMLKHQDSVSKIQVQLEIQ-ETSEGEGRSIPDKNSMFVHQDSVSKLQM 182
+ E N +L+ + + QL Q +EG+ R + D+ + ++ K Q+
Sbjct: 801 KGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQV 860
Query: 183 QEKKKITPGRERRNTRIV--VPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPL--- 237
+E K+ + R N + + + NE Q ++ + E +Q+ G+ + F L
Sbjct: 861 KELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETK-AESEQLARGLLEEQYFELTQE 919
Query: 238 ----------EIKKKDISLEHL------LPEEKVLLSRSESQ----TKKLQAKVTSRKKT 277
EI KD ++ L L ++ +L R + KK + + K+
Sbjct: 920 SKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEE 979
Query: 278 DIESLRGALGRRLLNDE-FKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDER 336
+I +L+ A + + + KTQ+ + +L + R +FK K D R
Sbjct: 980 EISNLKAAFEKNINTERTLKTQA-------VNKLAEIMNR----KDFKIDRKKANTQDLR 1028
Query: 337 LHSTTERGTINDAIKTQLKRKSYPETVLKHLKGVN 371
R ++ +R+ + + V+KH K +N
Sbjct: 1029 KKEKENRKL---QLELNQEREKFNQMVVKHQKELN 1060
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 45.1 bits (105), Expect = 2e-04
Identities = 73/360 (20%), Positives = 151/360 (41%), Gaps = 35/360 (9%)
Query: 3 EEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI 62
E+ E+ Q E R+ E + LS + Q++ + E + + + L
Sbjct: 641 EQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLR 700
Query: 63 --LRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLE--HQDSVSKLEMQIEKTKK 118
L Q ++ ++ K ++ L+ + E + L + ++ +L Q+E +K
Sbjct: 701 EELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERK 760
Query: 119 ---LPREKRHSTHDEESGENPMLKHQDSVSKIQVQL-EIQETSEGEGRSIPDKNSMFVHQ 174
EK HS E + KH++ VS +Q ++ E Q+ E + + + VHQ
Sbjct: 761 EAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQLQKCLGQVEHRVHQ 820
Query: 175 DS---------VSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQI 225
S +S L ++++++ ERR ++ ++ V++ ++ + + +E+KQ
Sbjct: 821 KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMA---KAREQYEAEERKQ- 876
Query: 226 NSGVERHKTFPLEIKKK--DISLEHLLPEE----KVLLSRSESQTKKLQAKVTSRKKTDI 279
+ + H T LE ++ + LE + E+ + L R Q +KLQ + +T
Sbjct: 877 RAELLGHLTGELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQ-DLELDLETRA 935
Query: 280 ESLRGALGRRLLNDEFKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHS 339
+ ++ L + +E + K +QL D + LK E T + E ++ H+
Sbjct: 936 KDVKARLALLEVQEETARREK-------QQLLDVQRQVALKSEEATATHQQLEEAQKEHT 988
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 45.1 bits (105), Expect = 2e-04
Identities = 72/366 (19%), Positives = 151/366 (41%), Gaps = 43/366 (11%)
Query: 1 MTEEQTYQAAEKSQAHNEVP-NERLVVEHQESLSKTKLQIKKQE---TSTEQPLTTPDK- 55
++ E+ Q E+ Q +E+ +E++ E +E + +++ +E EQ D+
Sbjct: 233 ISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADER 292
Query: 56 ---EPNENLILRHQDSMSKSE---MQVKEQRTLKGQRIITHDEEPG---KNLVLEHQDSV 106
E E + ++ E M+ +E+R + ++ I +E+ + + E +
Sbjct: 293 ARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRA 352
Query: 107 SKLEMQIEKTKKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPD 166
++ +I++ +K E+R EE E ++ Q +++ + + ++ +G +
Sbjct: 353 AEERQRIKEEEKRAAEERQRARAEEE-EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQ 411
Query: 167 K------NSMFVHQD----SVSKLQMQEK-KKITPGRER-RNTRIVVPNENVISVHQDSK 214
K N +D +V K Q +EK K+ RE+ + + E + +D K
Sbjct: 412 KIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEI----KDEK 467
Query: 215 SKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLS----RSESQTKKLQAK 270
K + K+++ S ++R K F + + H L + S R+ TK+ +
Sbjct: 468 IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGA 527
Query: 271 VTSRKKTDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSL 330
+E LR G +T+S+ F +Q A + LK + + R K L
Sbjct: 528 PQVEAGKRLEELRRRRG--------ETESEEFEKLKQKQQEAALELEELKKKREERRKVL 579
Query: 331 PETDER 336
E ++R
Sbjct: 580 EEEEQR 585
Score = 35.4 bits (80), Expect = 0.16
Identities = 56/287 (19%), Positives = 111/287 (38%), Gaps = 49/287 (17%)
Query: 3 EEQTYQAAEKSQAH-NEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENL 61
E Q +A E+ +A E + + E + ++ +TK++ +K E E K + L
Sbjct: 369 ERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKL 428
Query: 62 ---ILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKK 118
+L+ Q +++Q K ++ + E + + K E++ EK KK
Sbjct: 429 QTAVLKKQGEEKGTKVQAKREK------------------LQEDKPTFKKEEIKDEKIKK 470
Query: 119 --LPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDS 176
P+E+ S D + G + +++ S GR+ D +++
Sbjct: 471 DKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDT------KEA 524
Query: 177 VSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFP 236
Q++ K++ R RR + + + ++KQ + +E
Sbjct: 525 EGAPQVEAGKRLEELRRRRG--------------ETESEEFEKLKQKQQEAALELE---- 566
Query: 237 LEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLR 283
E+KKK +L EE+ + E+ K + + R K +IE R
Sbjct: 567 -ELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRR 612
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
1 [Homo sapiens]
Length = 1722
Score = 45.1 bits (105), Expect = 2e-04
Identities = 82/460 (17%), Positives = 189/460 (41%), Gaps = 56/460 (12%)
Query: 71 KSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDE 130
+ E++ KE++TLK QR +E+ + + + + +++ +K + + ++++ +DE
Sbjct: 178 QKELEDKEKQTLKAQR--DREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDE 235
Query: 131 ESGENPMLK-----HQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEK 185
E + K H++ + + +Q+E +E + + + +KNS+ Q++ + +++Q K
Sbjct: 236 LYKEEKIWKEKFKQHEEYIRNLHLQME-EERTRFKDQQEKEKNSLLKQQNNAA-VKIQAK 293
Query: 186 KKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDIS 245
K + I Q K + QE K+ + + + + E +K +
Sbjct: 294 YK---------AFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKE----EENRKRLE 340
Query: 246 LEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLR-------------GALGRRLLN 292
E + EE+ + + + +K + K KK ++ R A + +++
Sbjct: 341 EEQRIKEER---KKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQQLIIS 397
Query: 293 DEFKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPET------DERLHSTTERGTI 346
K + +E +++ G DI K+ SK + + + +R TI
Sbjct: 398 SALKKSGYNNKHLSLEDISNDKG-DIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTI 456
Query: 347 -NDAIKTQLKRKSYPETVLKHLK------GVNGKDIIKHLINIQSKSHGETDKNFFAYAT 399
++I+ +LK +T+L K + K + L+ + K +K +
Sbjct: 457 LKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSD 516
Query: 400 GRGLMKESTTTQ-LKSHPETDKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRD 458
+G +KE Q LKS + +++ + I G T + H + E +K +
Sbjct: 517 LKGNLKEQFPLQELKSDAQKEEKIMKHVINEN--TGQKTQIILGHNQEISE-VKTNEEQK 573
Query: 459 IIKGPISAQLKSHQETDVEPLTNAIGSSKTIGEIKTQLRT 498
IIK +++ ++ +++ + K I + R+
Sbjct: 574 IIKDNQQKKIQKVEKEEIQEQNGLLYKDKDTLVISVKQRS 613
>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
2 [Homo sapiens]
Length = 1336
Score = 45.1 bits (105), Expect = 2e-04
Identities = 82/460 (17%), Positives = 189/460 (41%), Gaps = 56/460 (12%)
Query: 71 KSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDE 130
+ E++ KE++TLK QR +E+ + + + + +++ +K + + ++++ +DE
Sbjct: 178 QKELEDKEKQTLKAQR--DREEKQFQEEEEKRHCWMKQFKVEKKKLENIQKQEQDKMNDE 235
Query: 131 ESGENPMLK-----HQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEK 185
E + K H++ + + +Q+E +E + + + +KNS+ Q++ + +++Q K
Sbjct: 236 LYKEEKIWKEKFKQHEEYIRNLHLQME-EERTRFKDQQEKEKNSLLKQQNNAA-VKIQAK 293
Query: 186 KKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDIS 245
K + I Q K + QE K+ + + + + E +K +
Sbjct: 294 YK---------AFVAYQKYGPIIKEQIESKKRKAQEWKEKEAKIRQKE----EENRKRLE 340
Query: 246 LEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLR-------------GALGRRLLN 292
E + EE+ + + + +K + K KK ++ R A + +++
Sbjct: 341 EEQRIKEER---KKQKEEERKRREKEYEEKKNIVKQEREQLISKEKIILREDASQQLIIS 397
Query: 293 DEFKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPET------DERLHSTTERGTI 346
K + +E +++ G DI K+ SK + + + +R TI
Sbjct: 398 SALKKSGYNNKHLSLEDISNDKG-DIAKNLVDENSKKQEDVLLWLVEESNMKENVDRQTI 456
Query: 347 -NDAIKTQLKRKSYPETVLKHLK------GVNGKDIIKHLINIQSKSHGETDKNFFAYAT 399
++I+ +LK +T+L K + K + L+ + K +K +
Sbjct: 457 LKESIQVKLKESISSQTILADFKMEEKNENLAKKRCSEELVKQERKYENTDNKTELGNSD 516
Query: 400 GRGLMKESTTTQ-LKSHPETDKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRD 458
+G +KE Q LKS + +++ + I G T + H + E +K +
Sbjct: 517 LKGNLKEQFPLQELKSDAQKEEKIMKHVINEN--TGQKTQIILGHNQEISE-VKTNEEQK 573
Query: 459 IIKGPISAQLKSHQETDVEPLTNAIGSSKTIGEIKTQLRT 498
IIK +++ ++ +++ + K I + R+
Sbjct: 574 IIKDNQQKKIQKVEKEEIQEQNGLLYKDKDTLVISVKQRS 613
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 44.3 bits (103), Expect = 3e-04
Identities = 102/536 (19%), Positives = 215/536 (40%), Gaps = 89/536 (16%)
Query: 11 EKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMS 70
++ + H++ + ++ EH+ S+ +T+ +K Q E L DK E HQ +
Sbjct: 726 DEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKE-----HQAHVE 780
Query: 71 KSEMQVKEQR-----------TLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQI--EKTK 117
E +K + + TH++ +++ +++L+ ++ +T+
Sbjct: 781 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKA------YEEQLAQLQQKLLDLETE 834
Query: 118 KLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSV 177
++ K+ + E+ + + D+ KIQVQ +Q+ +K + + Q
Sbjct: 835 RILLTKQ--VAEVEAQKKDVCTELDA-HKIQVQDLMQQL---------EKQNSEMEQKVK 882
Query: 178 SKLQMQEKKKITPGRERRNTR-IVVPNENVISVHQDSKSKLQMQE--KKQINSGVERHKT 234
S Q+ E K +E+ T+ I+V EN+I LQM+E KK+I
Sbjct: 883 SLTQVYESKLEDGNKEQEQTKQILVEKENMI---------LQMREGQKKEI--------- 924
Query: 235 FPLEIKKKDISLEHLLPEEKVLLSRSESQTK-KLQAKVTSRKKTDIESLRGALGRRLLND 293
EI + +S + E+ + + E +TK K Q K + K + ++ L ++LL+
Sbjct: 925 ---EILTQKLSAK----EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQ 977
Query: 294 EFKTQSK-SFPGPDIEQLTDAFGRDILKDEFKTRSKSLPET--------DERLHSTTE-- 342
E K + + ++ Q F +L + + S + + E++ S TE
Sbjct: 978 EAKLKKELENTALELSQKEKQFNAKML-EMAQANSAGISDAVSRLETNQKEQIESLTEVH 1036
Query: 343 RGTINDAIKTQLKRKSYPETVLKHLKGVNGKDIIKHLINIQSK-----SHGETDKNFFAY 397
R +ND I K+ + L+ + + ++ + + ++ K E +
Sbjct: 1037 RRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITW 1096
Query: 398 ATGRGLMKESTTTQLKSHPETDKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGR 457
G+ +++T +L +E L + T+LK+H E + L ++
Sbjct: 1097 LKEEGVKQDTTLNEL-------QEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKE 1149
Query: 458 DIIKGPISAQLKSHQETDVEPLTNAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQ 513
+ +LK E D ++ KT E L++ ++ + +D S++
Sbjct: 1150 NTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLE 1205
Score = 43.5 bits (101), Expect = 6e-04
Identities = 92/510 (18%), Positives = 212/510 (41%), Gaps = 50/510 (9%)
Query: 29 QESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRTL-----K 83
Q++L KLQ+ KQ+ TE E + +L+ ++ + ++ ++ ++TL K
Sbjct: 623 QDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVK 682
Query: 84 GQRIITHDEEPGKNLVLEH--QDSVSKLEMQIEKTKKLPREK--RHSTHDEESGENPMLK 139
+ + E + L H ++ +S L+ Q +K K+ K H ++ ++ + +
Sbjct: 683 QTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKE 742
Query: 140 HQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRERRNTRI 199
H+ S+ + + L+ Q DK+ + HQ V L+ + K+ ++ + ++
Sbjct: 743 HEVSIQRTEKALKDQINQLELLLKERDKH-LKEHQAHVENLE-ADIKRSEGELQQASAKL 800
Query: 200 VVPNENVISVHQDSKS---KLQMQEKKQINSGVER----HKTFPLEIKKKDISLEHLLPE 252
V + H+ +K+ +L ++K ++ ER + +E +KKD+ E L
Sbjct: 801 DVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTE--LDA 858
Query: 253 EKV----LLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSKSFPGPDIE 308
K+ L+ + E Q +++ KV S + L + + + ++ I
Sbjct: 859 HKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENM----IL 914
Query: 309 QLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLK 368
Q+ R+ K E + ++ L ++ +H +N+ +T+ K + +K
Sbjct: 915 QM-----REGQKKEIEILTQKLSAKEDSIH------ILNEEYETKFKNQEKKMEKVKQKA 963
Query: 369 GVNGKDIIKHLINIQSKSHGETDKNFFAYATGRGLMKESTTTQLKSHPETDKEFLADAIG 428
+ + K L++ ++K E + A ++ ++ + + ++DA+
Sbjct: 964 KEMQETLKKKLLDQEAKLKKELENT----ALELSQKEKQFNAKMLEMAQANSAGISDAVS 1019
Query: 429 RGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVEPLTNAIGSSKT 488
R + Q++S E + L D I I + ++ Q + QE L +
Sbjct: 1020 R--LETNQKEQIESLTEVHRRELNDVI--SIWEKKLNQQAEELQEIHEIQLQE---KEQE 1072
Query: 489 IGEIKTQLRTHYDVNLFKNKDMSVQRQEGI 518
+ E+K ++ NK+++ ++EG+
Sbjct: 1073 VAELKQKILLFGCEKEEMNKEITWLKEEGV 1102
Score = 33.9 bits (76), Expect = 0.46
Identities = 97/474 (20%), Positives = 178/474 (37%), Gaps = 95/474 (20%)
Query: 5 QTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILR 64
Q A+EK ++ E + +L K +L+ KK E S+ T + N+ L+
Sbjct: 1330 QQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLT-----DLNVQLQ 1384
Query: 65 HQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKR 124
+ S+S+ E + R +DEE + L D V L +++ K
Sbjct: 1385 NSISLSEKEAAISSLRK-------QYDEEKCELL-----DQVQDLSFKVDTLSKEKISAL 1432
Query: 125 HSTHD--------EESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDS 176
D ++ ++ +HQ++V ++Q+QLE+ K+ +D
Sbjct: 1433 EQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLEL-------------KSKEAYEKDE 1479
Query: 177 VSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQE---KKQINSGVERHK 233
L +E +++N R + + +D KSK++ +E + ++ S R
Sbjct: 1480 QINLLKEE-------LDQQNKRF----DCLKGEMEDDKSKMEKKESNLETELKSQTARIM 1528
Query: 234 TFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLND 293
I +K I +E L +VL ++ +Q K ++ K +K + L R+
Sbjct: 1529 ELEDHITQKTIEIESL---NEVL--KNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEA 1583
Query: 294 EFK--TQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTIN---- 347
E K T E T + + K++ + L ++RL S +
Sbjct: 1584 EEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRK 1643
Query: 348 -----DAIKTQL------KRKSYPETVLKHLKGVNGK--------DIIKHLINIQSKSHG 388
AIK QL K + Y + HL +N K I++ + S
Sbjct: 1644 AEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQS 1703
Query: 389 ET------DKNFFAY-----ATGRGLMKESTTTQLK--SHPETDKEFLADAIGR 429
ET KN AY A +G ++++ ++ T+KE L +G+
Sbjct: 1704 ETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQ 1757
Score = 33.1 bits (74), Expect = 0.79
Identities = 51/244 (20%), Positives = 103/244 (42%), Gaps = 16/244 (6%)
Query: 11 EKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLI---LRHQD 67
EK E + L +E+Q K +L+ KK+E L+ KE + L +
Sbjct: 1575 EKDNRVKEAEEKILTLENQVYSMKAELETKKKELE-HVNLSVKSKEEELKALEDRLESES 1633
Query: 68 SMSKSEMQVKEQRTLKG--QRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRH 125
+ +E++ K ++ + +++++ EE + + +S+L ++++ ++
Sbjct: 1634 AAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEE 1693
Query: 126 STHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEK 185
ES ++ L S + E QE ++ +G + + SV + + EK
Sbjct: 1694 KLKSVESSQSETLIVPRSAKNVAAYTE-QEEADSQG----CVQKTYEEKISVLQRNLTEK 1748
Query: 186 KKITP--GRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQ-INSGVERHKTFPLEIKKK 242
+K+ G+E+ T V + + +Q+ KL+ E KQ + + H LE K K
Sbjct: 1749 EKLLQRVGQEKEET--VSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNK 1806
Query: 243 DISL 246
SL
Sbjct: 1807 KYSL 1810
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 43.9 bits (102), Expect = 4e-04
Identities = 70/359 (19%), Positives = 150/359 (41%), Gaps = 41/359 (11%)
Query: 29 QESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRTLKGQRII 88
+ SL + ++I EQ + ++ LR Q + ++ K QRT + R +
Sbjct: 1602 RRSLKEQAIKITNLTQQLEQASIVKKRSEDD---LRQQRDVLDGHLREK-QRTQEELRRL 1657
Query: 89 THDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHD--------EESGENPMLKH 140
+ + E + +L+ Q+SV + ++ E +K +K S ++ + EN +H
Sbjct: 1658 SSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEH 1717
Query: 141 QDSVSKIQ-VQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKI-------TPGR 192
+++ ++LE + G + DKN+ + + S+LQ+ + + R
Sbjct: 1718 LMLEEELRNLRLEYDDLRRGRSEADSDKNATIL--ELRSQLQISNNRTLELQGLINDLQR 1775
Query: 193 ERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPE 252
ER N R + E ++ +++Q + K Q V+ ++ ++IK +L +
Sbjct: 1776 ERENLRQEI--EKFQKQALEASNRIQ-ESKNQCTQVVQERESLLVKIK--------VLEQ 1824
Query: 253 EKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLND--EFKTQ----SKSFPGPD 306
+K L R E + + AK T +T ++ +++ ND ++KTQ ++ +
Sbjct: 1825 DKARLQRLEDELNR--AKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIE 1882
Query: 307 IEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVLK 365
E+ ++ L+ E + + +ER E T + + +R Y + K
Sbjct: 1883 SEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQREIDK 1941
Score = 36.2 bits (82), Expect = 0.094
Identities = 74/378 (19%), Positives = 161/378 (42%), Gaps = 53/378 (14%)
Query: 11 EKSQAHNEVPNERLVVEHQESLSKTKLQIKK----QETSTEQPLTTPDKEPNENLILRHQ 66
E S+ N E + +++Q +T++ I K Q T ++ T+ + +NL R
Sbjct: 1347 ELSKVRNNYDEEIISLKNQ---FETEINITKTTIHQLTMQKEEDTSGYRAQIDNLT-REN 1402
Query: 67 DSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHS 126
S+S+ ++K T + + +E+ + + S K ++++E + S
Sbjct: 1403 RSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEES 1462
Query: 127 THDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVH------------Q 174
++S ++ QD +I+ ++ + + + + D+N+
Sbjct: 1463 VRYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSAT 1522
Query: 175 DSVSKLQMQEKK--KITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERH 232
++++KL++QE++ ++ ER + V +++ I+ Q+S +LQ+Q K+++ + R
Sbjct: 1523 ETINKLKVQEQELTRLRIDYERVSQERTVKDQD-ITRFQNSLKELQLQ-KQKVEEELNRL 1580
Query: 233 KTFPLEIKKKDISLEHLLP------EEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGAL 286
K E K LE L +E+ + + +Q + + V R + D+ R L
Sbjct: 1581 KRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVL 1640
Query: 287 GRRLLNDEFKTQSKSFPGPDIEQLTDAFGRDILKDE----------------FKTRSKSL 330
L ++ +TQ + + +A R +L+++ + +S+SL
Sbjct: 1641 DGH-LREKQRTQEEL---RRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSL 1696
Query: 331 PETD---ERLHSTTERGT 345
E+ ERL S TE T
Sbjct: 1697 NESKIEIERLQSLTENLT 1714
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 43.9 bits (102), Expect = 4e-04
Identities = 106/553 (19%), Positives = 220/553 (39%), Gaps = 86/553 (15%)
Query: 5 QTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILR 64
Q QA K A + E + E E ++ KLQ++K + K +E L++
Sbjct: 939 QQLQAERKKMAQQMLDLEEQLEE--EEAARQKLQLEKVTAEAKIK-----KLEDEILVMD 991
Query: 65 HQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVL---EHQDSVSKLEMQIEKTKKLPR 121
Q++ E ++ E+R + +EE KNL +H+ +S+LE++++K +K +
Sbjct: 992 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 122 EKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQ 181
E + K++ +L EG+ ++ + Q + K+Q
Sbjct: 1052 E---------------------LEKLKRKL------EGDASDFHEQIADLQAQIAELKMQ 1084
Query: 182 MQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKK 241
+ +K++ R + N + ++ + + ++ + R+K E +K
Sbjct: 1085 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA---EKQK 1141
Query: 242 KDI--SLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQS 299
+D+ LE L E + L + +Q ++L+AK ++ ++ L+ AL + E + Q
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQ-QELRAK----REQEVTVLKKALDEETRSHEAQVQE 1196
Query: 300 -KSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKS 358
+ +E+LT+ ++FK +L + + L N + +L+
Sbjct: 1197 MRQKHAQAVEELTEQL------EQFKRAKANLDKNKQTLEKE------NADLAGELRVLG 1244
Query: 359 YPETVLKHLKGVNGKDIIKHLINIQSK-SHGETDKNFFAYATGRGLMKESTTTQLKSHPE 417
+ ++H K K + + +QSK S GE R + + +L++ E
Sbjct: 1245 QAKQEVEHKK----KKLEAQVQELQSKCSDGE---------RARAELNDK-VHKLQNEVE 1290
Query: 418 TDKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVE 477
+ L +A G+ I + L S + +ELL++ + + QL+ + + +
Sbjct: 1291 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1350
Query: 478 PLTNAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQRQEGIFTRSIT---PSKFPTKVIN 534
L + E K L H + D + Q+ T +F ++ N
Sbjct: 1351 QLDEEM-------EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1403
Query: 535 LS-PFENKEETYE 546
L+ +E K Y+
Sbjct: 1404 LTQQYEEKAAAYD 1416
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/413 (19%), Positives = 161/413 (38%), Gaps = 58/413 (14%)
Query: 2 TEEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENL 61
T Q E Q H + E + E E + K + K + + E+ EN
Sbjct: 1187 TRSHEAQVQEMRQKHAQAVEE--LTEQLEQFKRAKANLDKNKQTLEK----------ENA 1234
Query: 62 ILRHQDSM---SKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKT-- 116
L + + +K E++ K+++ + + G+ E D V KL+ ++E
Sbjct: 1235 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTG 1294
Query: 117 -------KKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPD--- 166
K + K ++ + + L +++ K+ V ++++ E E S+ D
Sbjct: 1295 MLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE-ERNSLQDQLD 1353
Query: 167 -----KNSMFVH------QDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQD--- 212
K ++ H Q S SK ++Q+ E R EN+ +++
Sbjct: 1354 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1413
Query: 213 -------SKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTK 265
+K++LQ QE + ++ + ++KK + LL EEK + S+ +
Sbjct: 1414 AYDKLEKTKNRLQ-QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1472
Query: 266 KLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLT---DAFGRDILKDE 322
+ +A+ K+T SL AL L E ++ ++E L D G+++ E
Sbjct: 1473 RAEAE-AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV--HE 1529
Query: 323 FKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKGVNGKDI 375
+ ++L E + + E + D ++ K E ++ LKG +D+
Sbjct: 1530 LEKSKRALETQMEEMKTQLEE--LEDELQATEDAKLRLEVNMQALKGQFERDL 1580
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 43.9 bits (102), Expect = 4e-04
Identities = 106/553 (19%), Positives = 220/553 (39%), Gaps = 86/553 (15%)
Query: 5 QTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILR 64
Q QA K A + E + E E ++ KLQ++K + K +E L++
Sbjct: 946 QQLQAERKKMAQQMLDLEEQLEE--EEAARQKLQLEKVTAEAKIK-----KLEDEILVMD 998
Query: 65 HQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVL---EHQDSVSKLEMQIEKTKKLPR 121
Q++ E ++ E+R + +EE KNL +H+ +S+LE++++K +K +
Sbjct: 999 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 122 EKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQ 181
E + K++ +L EG+ ++ + Q + K+Q
Sbjct: 1059 E---------------------LEKLKRKL------EGDASDFHEQIADLQAQIAELKMQ 1091
Query: 182 MQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKK 241
+ +K++ R + N + ++ + + ++ + R+K E +K
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA---EKQK 1148
Query: 242 KDI--SLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQS 299
+D+ LE L E + L + +Q ++L+AK ++ ++ L+ AL + E + Q
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQ-QELRAK----REQEVTVLKKALDEETRSHEAQVQE 1203
Query: 300 -KSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKS 358
+ +E+LT+ ++FK +L + + L N + +L+
Sbjct: 1204 MRQKHAQAVEELTEQL------EQFKRAKANLDKNKQTLEKE------NADLAGELRVLG 1251
Query: 359 YPETVLKHLKGVNGKDIIKHLINIQSK-SHGETDKNFFAYATGRGLMKESTTTQLKSHPE 417
+ ++H K K + + +QSK S GE R + + +L++ E
Sbjct: 1252 QAKQEVEHKK----KKLEAQVQELQSKCSDGE---------RARAELNDK-VHKLQNEVE 1297
Query: 418 TDKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVE 477
+ L +A G+ I + L S + +ELL++ + + QL+ + + +
Sbjct: 1298 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1357
Query: 478 PLTNAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQRQEGIFTRSIT---PSKFPTKVIN 534
L + E K L H + D + Q+ T +F ++ N
Sbjct: 1358 QLDEEM-------EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1410
Query: 535 LS-PFENKEETYE 546
L+ +E K Y+
Sbjct: 1411 LTQQYEEKAAAYD 1423
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/413 (19%), Positives = 161/413 (38%), Gaps = 58/413 (14%)
Query: 2 TEEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENL 61
T Q E Q H + E + E E + K + K + + E+ EN
Sbjct: 1194 TRSHEAQVQEMRQKHAQAVEE--LTEQLEQFKRAKANLDKNKQTLEK----------ENA 1241
Query: 62 ILRHQDSM---SKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKT-- 116
L + + +K E++ K+++ + + G+ E D V KL+ ++E
Sbjct: 1242 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTG 1301
Query: 117 -------KKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPD--- 166
K + K ++ + + L +++ K+ V ++++ E E S+ D
Sbjct: 1302 MLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE-ERNSLQDQLD 1360
Query: 167 -----KNSMFVH------QDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQD--- 212
K ++ H Q S SK ++Q+ E R EN+ +++
Sbjct: 1361 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1420
Query: 213 -------SKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTK 265
+K++LQ QE + ++ + ++KK + LL EEK + S+ +
Sbjct: 1421 AYDKLEKTKNRLQ-QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1479
Query: 266 KLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLT---DAFGRDILKDE 322
+ +A+ K+T SL AL L E ++ ++E L D G+++ E
Sbjct: 1480 RAEAE-AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV--HE 1536
Query: 323 FKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKGVNGKDI 375
+ ++L E + + E + D ++ K E ++ LKG +D+
Sbjct: 1537 LEKSKRALETQMEEMKTQLEE--LEDELQATEDAKLRLEVNMQALKGQFERDL 1587
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 43.9 bits (102), Expect = 4e-04
Identities = 106/553 (19%), Positives = 220/553 (39%), Gaps = 86/553 (15%)
Query: 5 QTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILR 64
Q QA K A + E + E E ++ KLQ++K + K +E L++
Sbjct: 946 QQLQAERKKMAQQMLDLEEQLEE--EEAARQKLQLEKVTAEAKIK-----KLEDEILVMD 998
Query: 65 HQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVL---EHQDSVSKLEMQIEKTKKLPR 121
Q++ E ++ E+R + +EE KNL +H+ +S+LE++++K +K +
Sbjct: 999 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1058
Query: 122 EKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQ 181
E + K++ +L EG+ ++ + Q + K+Q
Sbjct: 1059 E---------------------LEKLKRKL------EGDASDFHEQIADLQAQIAELKMQ 1091
Query: 182 MQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKK 241
+ +K++ R + N + ++ + + ++ + R+K E +K
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA---EKQK 1148
Query: 242 KDI--SLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQS 299
+D+ LE L E + L + +Q ++L+AK ++ ++ L+ AL + E + Q
Sbjct: 1149 RDLGEELEALKTELEDTLDSTATQ-QELRAK----REQEVTVLKKALDEETRSHEAQVQE 1203
Query: 300 -KSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKS 358
+ +E+LT+ ++FK +L + + L N + +L+
Sbjct: 1204 MRQKHAQAVEELTEQL------EQFKRAKANLDKNKQTLEKE------NADLAGELRVLG 1251
Query: 359 YPETVLKHLKGVNGKDIIKHLINIQSK-SHGETDKNFFAYATGRGLMKESTTTQLKSHPE 417
+ ++H K K + + +QSK S GE R + + +L++ E
Sbjct: 1252 QAKQEVEHKK----KKLEAQVQELQSKCSDGE---------RARAELNDK-VHKLQNEVE 1297
Query: 418 TDKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVE 477
+ L +A G+ I + L S + +ELL++ + + QL+ + + +
Sbjct: 1298 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1357
Query: 478 PLTNAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQRQEGIFTRSIT---PSKFPTKVIN 534
L + E K L H + D + Q+ T +F ++ N
Sbjct: 1358 QLDEEM-------EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1410
Query: 535 LS-PFENKEETYE 546
L+ +E K Y+
Sbjct: 1411 LTQQYEEKAAAYD 1423
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/413 (19%), Positives = 161/413 (38%), Gaps = 58/413 (14%)
Query: 2 TEEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENL 61
T Q E Q H + E + E E + K + K + + E+ EN
Sbjct: 1194 TRSHEAQVQEMRQKHAQAVEE--LTEQLEQFKRAKANLDKNKQTLEK----------ENA 1241
Query: 62 ILRHQDSM---SKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKT-- 116
L + + +K E++ K+++ + + G+ E D V KL+ ++E
Sbjct: 1242 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTG 1301
Query: 117 -------KKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPD--- 166
K + K ++ + + L +++ K+ V ++++ E E S+ D
Sbjct: 1302 MLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE-ERNSLQDQLD 1360
Query: 167 -----KNSMFVH------QDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQD--- 212
K ++ H Q S SK ++Q+ E R EN+ +++
Sbjct: 1361 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1420
Query: 213 -------SKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTK 265
+K++LQ QE + ++ + ++KK + LL EEK + S+ +
Sbjct: 1421 AYDKLEKTKNRLQ-QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1479
Query: 266 KLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLT---DAFGRDILKDE 322
+ +A+ K+T SL AL L E ++ ++E L D G+++ E
Sbjct: 1480 RAEAE-AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV--HE 1536
Query: 323 FKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKGVNGKDI 375
+ ++L E + + E + D ++ K E ++ LKG +D+
Sbjct: 1537 LEKSKRALETQMEEMKTQLEE--LEDELQATEDAKLRLEVNMQALKGQFERDL 1587
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 43.9 bits (102), Expect = 4e-04
Identities = 106/553 (19%), Positives = 220/553 (39%), Gaps = 86/553 (15%)
Query: 5 QTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILR 64
Q QA K A + E + E E ++ KLQ++K + K +E L++
Sbjct: 939 QQLQAERKKMAQQMLDLEEQLEE--EEAARQKLQLEKVTAEAKIK-----KLEDEILVMD 991
Query: 65 HQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVL---EHQDSVSKLEMQIEKTKKLPR 121
Q++ E ++ E+R + +EE KNL +H+ +S+LE++++K +K +
Sbjct: 992 DQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQ 1051
Query: 122 EKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQ 181
E + K++ +L EG+ ++ + Q + K+Q
Sbjct: 1052 E---------------------LEKLKRKL------EGDASDFHEQIADLQAQIAELKMQ 1084
Query: 182 MQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKK 241
+ +K++ R + N + ++ + + ++ + R+K E +K
Sbjct: 1085 LAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKA---EKQK 1141
Query: 242 KDI--SLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQS 299
+D+ LE L E + L + +Q ++L+AK ++ ++ L+ AL + E + Q
Sbjct: 1142 RDLGEELEALKTELEDTLDSTATQ-QELRAK----REQEVTVLKKALDEETRSHEAQVQE 1196
Query: 300 -KSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKS 358
+ +E+LT+ ++FK +L + + L N + +L+
Sbjct: 1197 MRQKHAQAVEELTEQL------EQFKRAKANLDKNKQTLEKE------NADLAGELRVLG 1244
Query: 359 YPETVLKHLKGVNGKDIIKHLINIQSK-SHGETDKNFFAYATGRGLMKESTTTQLKSHPE 417
+ ++H K K + + +QSK S GE R + + +L++ E
Sbjct: 1245 QAKQEVEHKK----KKLEAQVQELQSKCSDGE---------RARAELNDK-VHKLQNEVE 1290
Query: 418 TDKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVE 477
+ L +A G+ I + L S + +ELL++ + + QL+ + + +
Sbjct: 1291 SVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQD 1350
Query: 478 PLTNAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQRQEGIFTRSIT---PSKFPTKVIN 534
L + E K L H + D + Q+ T +F ++ N
Sbjct: 1351 QLDEEM-------EAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1403
Query: 535 LS-PFENKEETYE 546
L+ +E K Y+
Sbjct: 1404 LTQQYEEKAAAYD 1416
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/413 (19%), Positives = 161/413 (38%), Gaps = 58/413 (14%)
Query: 2 TEEQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENL 61
T Q E Q H + E + E E + K + K + + E+ EN
Sbjct: 1187 TRSHEAQVQEMRQKHAQAVEE--LTEQLEQFKRAKANLDKNKQTLEK----------ENA 1234
Query: 62 ILRHQDSM---SKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKT-- 116
L + + +K E++ K+++ + + G+ E D V KL+ ++E
Sbjct: 1235 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTG 1294
Query: 117 -------KKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPD--- 166
K + K ++ + + L +++ K+ V ++++ E E S+ D
Sbjct: 1295 MLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEE-ERNSLQDQLD 1353
Query: 167 -----KNSMFVH------QDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQD--- 212
K ++ H Q S SK ++Q+ E R EN+ +++
Sbjct: 1354 EEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1413
Query: 213 -------SKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTK 265
+K++LQ QE + ++ + ++KK + LL EEK + S+ +
Sbjct: 1414 AYDKLEKTKNRLQ-QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 1472
Query: 266 KLQAKVTSRKKTDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLT---DAFGRDILKDE 322
+ +A+ K+T SL AL L E ++ ++E L D G+++ E
Sbjct: 1473 RAEAE-AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNV--HE 1529
Query: 323 FKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKGVNGKDI 375
+ ++L E + + E + D ++ K E ++ LKG +D+
Sbjct: 1530 LEKSKRALETQMEEMKTQLEE--LEDELQATEDAKLRLEVNMQALKGQFERDL 1580
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 43.9 bits (102), Expect = 4e-04
Identities = 109/516 (21%), Positives = 206/516 (39%), Gaps = 69/516 (13%)
Query: 14 QAHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSE 73
Q + V +R + E + ++ K +IK+ ET E T E + + L QD + K
Sbjct: 1098 QIQHVVEGKRALSELTQGVTCYKAKIKELETILE----TQKVECSHSAKLE-QDILEKES 1152
Query: 74 MQVKEQRTLKGQRIITHDEEPGKNLV------LEHQDSVSKLEMQIEKTKKLPREKRHST 127
+ +K +R LK H ++ KN L+ ++ +++L ++ K L + K
Sbjct: 1153 IILKLERNLK--EFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEE 1210
Query: 128 HDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKK 187
E LK + S S + Q + E K + D+ +++ +K+
Sbjct: 1211 ETNRQ-ETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKL---TDAKKQIKQVQKEV 1266
Query: 188 ITPGRERRNTRIVV----PNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKD 243
E + RI + +N S D K + Q K+Q+N+ E KD
Sbjct: 1267 SVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKD 1326
Query: 244 ISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKKTDIESLRGALGR-RLLNDEFKTQSKSF 302
++++ + E+ + + QT+ Q +V K ++E L L + + ++ +T++
Sbjct: 1327 LNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQR 1386
Query: 303 PGPDIEQLTDAFGR-DILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPE 361
+ E TD G+ L+DE L E++++ ++ K L+ K
Sbjct: 1387 SNKEHENNTDVLGKLTNLQDE-------LQESEQKYNADR---------KKWLEEKMMLI 1430
Query: 362 TVLKHLKGVNGKDIIKHLINIQSKSHGETDKNFFAYATGRGLMKESTTTQLKSHPETDKE 421
T K + + K++ K + E + FF E T QL E D +
Sbjct: 1431 TQAKEAENIRNKEM---------KKYAEDRERFFKQQN----EMEILTAQL---TEKDSD 1474
Query: 422 FLADAIGRGIIIGPITTQLK----SHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVE 477
R ++ + QLK S+ + D E+ + +K IS K ET +
Sbjct: 1475 LQKWREERDQLVAALEIQLKALISSNVQKDNEI-------EQLKRIISETSKI--ETQIM 1525
Query: 478 PLTNAIGSSKTIGEIKTQ-LRTHYDVNLFKNKDMSV 512
+ SS +++T+ L T ++++ K +D SV
Sbjct: 1526 DIKPKRISSADPDKLQTEPLSTSFEISRNKIEDGSV 1561
>gi|229577000 ecotropic viral integration site 5-like isoform 1
[Homo sapiens]
Length = 805
Score = 43.5 bits (101), Expect = 6e-04
Identities = 54/290 (18%), Positives = 123/290 (42%), Gaps = 53/290 (18%)
Query: 4 EQTYQAAEKSQAHNEVPNERLVVEHQESLSKTKLQIKKQETSTE-----QPLTTPDKEPN 58
E+ Y A + + ++ +RL E++ L K +++ ++E++ Q T +E
Sbjct: 364 EKEYAAMKSKEMEEQIEIKRLRTENR--LLKQRIETLEKESAALADRLIQGQVTRAQEAE 421
Query: 59 ENLILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKK 118
EN +++ + ++ + + + K Q I +E +N L +D VS LE ++E+++
Sbjct: 422 ENYVIKRELAVVRQQCSSAAEDLQKAQSTIRQLQEQQENPRLT-EDFVSHLETELEQSR- 479
Query: 119 LPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVS 178
L+ +++ ++ + E S+PD+N++ Q+ +
Sbjct: 480 -------------------LRETETLGALREMQDKVLDMEKRNSSLPDENNVAQLQEELK 520
Query: 179 KLQMQEKKKITPGRE-----------------RRNTRIVVPNENVISVHQDSKSKLQMQE 221
L+++E + + RE R P + V+ QD ++++E
Sbjct: 521 ALKVREGQAVASTRELKLQLQELSDTWQAHLARGGRWKESPRKLVVGELQDELMSVRLRE 580
Query: 222 KKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKV 271
+ + G E++++ + LE + LL+R E++ LQ K+
Sbjct: 581 AQALAEG--------RELRQRVVELETQDHIHRNLLNRVEAERAALQEKL 622
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,130,287
Number of Sequences: 37866
Number of extensions: 1065340
Number of successful extensions: 4099
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 413
Number of HSP's that attempted gapping in prelim test: 3637
Number of HSP's gapped (non-prelim): 803
length of query: 628
length of database: 18,247,518
effective HSP length: 108
effective length of query: 520
effective length of database: 14,157,990
effective search space: 7362154800
effective search space used: 7362154800
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.