Search of human proteins with 157674363

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157674363 protein phosphatase 1, regulatory subunit 15A
[Homo sapiens]
         (674 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo...  1391   0.0  
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom...    84   6e-16
gi|55956788 nucleolin [Homo sapiens]                                   77   7e-14
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              71   4e-12
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         70   5e-12
gi|21735415 centromere protein B [Homo sapiens]                        70   8e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     60   7e-09
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    60   7e-09
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    60   7e-09
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    60   7e-09
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [...    58   2e-08
gi|188219559 protein phosphatase 1, regulatory subunit 15B [Homo...    58   3e-08
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       57   6e-08
gi|157738619 smoothelin-like 1 [Homo sapiens]                          57   6e-08
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    57   7e-08
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    56   1e-07
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                55   2e-07
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 55   2e-07
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    55   2e-07
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    55   2e-07
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    55   2e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    54   4e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    54   4e-07
gi|55741677 SET domain containing 1A [Homo sapiens]                    54   5e-07
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]             54   5e-07
gi|119220598 apolipoprotein B48 receptor [Homo sapiens]                54   5e-07
gi|153791492 eukaryotic translation initiation factor 3, subunit...    54   6e-07
gi|209862789 microtubule associated monoxygenase, calponin and L...    54   6e-07
gi|83700233 eukaryotic translation initiation factor 3, subunit ...    54   6e-07
gi|4503525 eukaryotic translation initiation factor 3, subunit C...    54   6e-07

>gi|157674363 protein phosphatase 1, regulatory subunit 15A [Homo
           sapiens]
          Length = 674

 Score = 1391 bits (3601), Expect = 0.0
 Identities = 674/674 (100%), Positives = 674/674 (100%)

Query: 1   MAPGQAPHQATPWRDAHPFFLLSPVMGLLSRAWSRLRGLGPLEPWLVEAVKGAALVEAGL 60
           MAPGQAPHQATPWRDAHPFFLLSPVMGLLSRAWSRLRGLGPLEPWLVEAVKGAALVEAGL
Sbjct: 1   MAPGQAPHQATPWRDAHPFFLLSPVMGLLSRAWSRLRGLGPLEPWLVEAVKGAALVEAGL 60

Query: 61  EGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGE 120
           EGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGE
Sbjct: 61  EGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGE 120

Query: 121 REATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYP 180
           REATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYP
Sbjct: 121 REATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYP 180

Query: 181 PSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERS 240
           PSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERS
Sbjct: 181 PSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERS 240

Query: 241 KGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLK 300
           KGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLK
Sbjct: 241 KGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLK 300

Query: 301 SWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDE 360
           SWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDE
Sbjct: 301 SWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDE 360

Query: 361 DSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSA 420
           DSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSA
Sbjct: 361 DSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSA 420

Query: 421 STPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFR 480
           STPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFR
Sbjct: 421 STPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFR 480

Query: 481 GWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPET 540
           GWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPET
Sbjct: 481 GWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPET 540

Query: 541 PTHDPDPETPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQ 600
           PTHDPDPETPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQ
Sbjct: 541 PTHDPDPETPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQ 600

Query: 601 EELSPCLTPAARARAWARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVATPSRSS 660
           EELSPCLTPAARARAWARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVATPSRSS
Sbjct: 601 EELSPCLTPAARARAWARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVATPSRSS 660

Query: 661 AAAAAALDLSGRRG 674
           AAAAAALDLSGRRG
Sbjct: 661 AAAAAALDLSGRRG 674


>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
            sapiens]
          Length = 1152

 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 109/432 (25%), Positives = 154/432 (35%), Gaps = 77/432 (17%)

Query: 75   WGRRPEEEAEDSGGPGE-DRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQ 133
            W     E+ E   G GE +R   G K  +   E W   D ++    ERE       QG Q
Sbjct: 669  WQDEEREKGEKDKGRGEMERPGEGEKELAE-KEEWKKRDGEEQEQKERE-------QGHQ 720

Query: 134  FADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEE 193
                Q             +G ++  GE + EE    EEE            E      E+
Sbjct: 721  KERNQEME----------EGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREK 770

Query: 194  DDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSS 253
            ++ E  K+E           G +        GE E + TE +  E+ +G  +        
Sbjct: 771  EEGERKKEERAGKEEKGEEEGDQ--------GEGEEEETEGRGEEKEEGG-EVEGGEVEE 821

Query: 254  GSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGE 313
            G   R  E   GE  EE+E +  +E G+GE   G                 +   EEEGE
Sbjct: 822  GKGEREEEEEEGEG-EEEEGEGEEEEGEGEEEEG-----------------EGKGEEEGE 863

Query: 314  VKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEA 373
                G  E++GE                     GE  EEE + E +E+ +   +EEEGE 
Sbjct: 864  E---GEGEEEGEEG------------------EGEGEEEEGEGEGEEEGEGEGEEEEGEG 902

Query: 374  EASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWV 433
            E        G        + GE   EEE E+ +    E+E E E              W 
Sbjct: 903  EGEEEGEGEGE------EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE 956

Query: 434  YRPGE-DTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGK-ETE 491
                E + E EE+ + + E+ E + E   GE E +      ++     G G   G+ E E
Sbjct: 957  GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEG--EEEGEEEGEGEEEGEGEGE 1014

Query: 492  EEEAAEDWGEAE 503
            EEE  E  GE E
Sbjct: 1015 EEEEGEVEGEVE 1026



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 114/474 (24%), Positives = 163/474 (34%), Gaps = 93/474 (19%)

Query: 48   EAVKGAALVEAGLEGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEA 107
            E  KG   +E   EGE           W +R  EE E      ++RE    K  +   E 
Sbjct: 678  EKDKGRGEMERPGEGEKELA---EKEEWKKRDGEEQEQ-----KEREQGHQKERNQEMEE 729

Query: 108  WGLLDDDDGMY--GEREATSVPRGQGSQFADGQRAPLSPSLLIRTLQGS-DKNPGEEKAE 164
             G  +  +G    G+RE      G+G +  +G+            ++G  +K  GE K E
Sbjct: 730  GGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEE-----------VEGEREKEEGERKKE 778

Query: 165  EEGVAEEEGVNKFSYPPSHRECCPAVEEEDDE-------EAVKKEAHRTSTSALSPGSKP 217
            E    EE+G  +        E      EE +E       E  + +  R        G + 
Sbjct: 779  ERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEE 838

Query: 218  STWVSCPGEEENQATEDKRTE---RSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEK 274
                   GEEE    E++  E     +G           G      E   GE  EE E +
Sbjct: 839  EG----EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894

Query: 275  AHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPP 334
              +E G+GE     +     +  + K        EEEGE       E++GE E       
Sbjct: 895  GEEEEGEGEGEEEGEGEGEEEEGEGKG-------EEEGEEGEGEGEEEEGEGE------- 940

Query: 335  PSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPG 394
                        GED E E +EEE E      +EEEGE E        G        + G
Sbjct: 941  ------------GEDGEGEGEEEEGEWE---GEEEEGEGEGEEEGEGEG--------EEG 977

Query: 395  EDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKE 454
            E   EEE+ + +    E E E E                   GE+  E E E+ +  + E
Sbjct: 978  EGEGEEEEGEGEGEEEEGEEEGEEEGE---------------GEEEGEGEGEEEEEGEVE 1022

Query: 455  DDSEAALGEAESDPHPSH---PDQRAHFRGWGYRPGKETEEEEAA--EDWGEAE 503
             + E   GE E +         ++     G   R  +E EEEE    ++ GE E
Sbjct: 1023 GEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEE 1076



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 97/379 (25%), Positives = 135/379 (35%), Gaps = 50/379 (13%)

Query: 152 QGSDKNPGEEKAEEEGVAE---EEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTST 208
           +G  K+ GE +   EG  +   EEG +               E   DEE  K E  +   
Sbjct: 638 EGKAKSVGEAEDGPEGRGDGTCEEGSS-------------GAEHWQDEEREKGEKDKGRG 684

Query: 209 SALSPG------SKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEY 262
               PG      ++   W    GEE+ Q       ER +G +K        G +    E 
Sbjct: 685 EMERPGEGEKELAEKEEWKKRDGEEQEQK------EREQGHQKERNQEMEEGGEEEHGEG 738

Query: 263 RSGEASEEKEEKAH---KETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEG------- 312
              E   E+EE+     KE G+GE   G +     +R + +    +   EEEG       
Sbjct: 739 EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEE 798

Query: 313 -EVKALGAA-EKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEE---DEDSDSGSD 367
            E +  G   E+ GE E            +      GE+ E E +EEE   +E+   G  
Sbjct: 799 EETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKG 858

Query: 368 EEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEE---DEDSDTGSAEDEREAETSASTPP 424
           EEEGE          G          GE  EE E   +E+   G  E+E E E       
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918

Query: 425 ASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGY 484
                +      GE   EEE+ + + ED E + E   GE E +      +      G G 
Sbjct: 919 GKGEEEG---EEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEG- 974

Query: 485 RPGKETEEEEAAEDWGEAE 503
             G+   EEE  E  GE E
Sbjct: 975 EEGEGEGEEEEGEGEGEEE 993



 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 85/363 (23%), Positives = 138/363 (38%), Gaps = 40/363 (11%)

Query: 152 QGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSAL 211
           +G++ + G    E+E  A EE V         +E    + ++  ++A   E    S    
Sbjct: 591 EGAEDSKGNGIEEQEVEANEENVKVHG---GRKEKTEILSDDLTDKAEVSEGKAKSVGEA 647

Query: 212 SPGSKPSTWVSCP----GEEENQATEDKRTERSKGARKTSVSPRSSG--SDPRSWEYRSG 265
             G +     +C     G E  Q  E ++ E+ KG  +           ++   W+ R G
Sbjct: 648 EDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDG 707

Query: 266 EASEEKE-EKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEK-D 323
           E  E+KE E+ H++    E   G +        +      +  +E+EGE K  G  E+ +
Sbjct: 708 EEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDR--EEEEEKEGEGKEEGEGEEVE 765

Query: 324 GEAECPPCIPPPSAFLKAWVYWPGEDTEEE---EDEEEDEDSDSGSDEEEGEAEASSSTP 380
           GE E                   GE  +EE   ++E+ +E+ D G  EEE E E      
Sbjct: 766 GEREKEE----------------GERKKEERAGKEEKGEEEGDQGEGEEE-ETEGRGEEK 808

Query: 381 ATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDT 440
             G  ++    + G+   EEE+E+ +    E E E E                   GE+ 
Sbjct: 809 EEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE-------GKGEEE 861

Query: 441 EEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWG 500
            EE + + + E+ E + E   GE E +       +     G G   G+   EEE  E  G
Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKG 921

Query: 501 EAE 503
           E E
Sbjct: 922 EEE 924



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 92/380 (24%), Positives = 138/380 (36%), Gaps = 56/380 (14%)

Query: 78   RPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFADG 137
            + E E E+  G  E  E    K   +  E  G  + D G  GE E T    G+G +  +G
Sbjct: 756  KEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGE-GEEEETE---GRGEEKEEG 811

Query: 138  QRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDD-- 195
                         ++G +   G+ + EEE   EEEG  +        E     EEE +  
Sbjct: 812  GE-----------VEGGEVEEGKGEREEE---EEEGEGEEEEGEGEEEEGEGEEEEGEGK 857

Query: 196  --EEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSS 253
              EE  + E           G +        GE E +   +   E  +G  +        
Sbjct: 858  GEEEGEEGEGEEEGEEGEGEGEEEE------GEGEGEEEGEGEGEEEEGEGEGEEEGEGE 911

Query: 254  GSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGE 313
            G +    E +  E  EE E +  +E G+GE   G       +  + +  W    +E EGE
Sbjct: 912  GEEEEG-EGKGEEEGEEGEGEGEEEEGEGEGEDGE-----GEGEEEEGEWEGEEEEGEGE 965

Query: 314  VKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEA 373
                G  E +GE E                   GE+  EEE E E+E    G +EEEGE 
Sbjct: 966  ----GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV 1021

Query: 374  EAS-SSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAW 432
            E         G   +    + GE+ E+E + + +  + E+E E E               
Sbjct: 1022 EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKY------------ 1069

Query: 433  VYRPGEDTEEEEDEDVDSED 452
                 ++T EEE+E  D E+
Sbjct: 1070 -----QETGEEENERQDGEE 1084


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 71/281 (25%), Positives = 114/281 (40%), Gaps = 21/281 (7%)

Query: 226 EEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAA 285
           EE+++  E    E    + +  V P+  G    +   +    S  K+        K    
Sbjct: 25  EEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVT 84

Query: 286 PGPQSSAPAQRPQLKSWWCQPSDEEEGEV--KALGAAE-KDGEAECPPCIPPPSAFLKAW 342
           PG +++A   +  +       +  ++G    KAL A   K G A     IP   A     
Sbjct: 85  PGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAA-----IPAKGAKNGKN 139

Query: 343 VYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEED 402
                 D EE++D EEDE+ D   DE+E E E ++   A             ED E++ED
Sbjct: 140 AKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASE-----DEDDEDDED 194

Query: 403 EDSDTGSAEDEREAETSASTPP----ASAFLKAWVYRPGEDTEEEE-DEDVDSEDKEDDS 457
           ++ D    ED+ E E   +TP     A+  +        ED +EEE DED D +D EDD 
Sbjct: 195 DEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDE 254

Query: 458 EAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAED 498
           +    + E D      ++    +    +  KE  +++AA +
Sbjct: 255 D---DDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPE 292



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 80/310 (25%), Positives = 131/310 (42%), Gaps = 37/310 (11%)

Query: 176 KFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDK 235
           K + PP   E     E+ +DEE  + E   +S   +    K     +    ++   +  K
Sbjct: 16  KMAPPPKEVE-----EDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTK 70

Query: 236 RTERSKGARKTSVSP-RSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSA-P 293
           +   +  A+K +V+P + + + P        +A     +K         A PG + +A P
Sbjct: 71  KVAVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIP 130

Query: 294 AQRPQL-KSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEE 352
           A+  +  K+   + SDEEE +       + + E E    I P  A +KA    P  + E+
Sbjct: 131 AKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEP--AAMKAAAAAPASEDED 188

Query: 353 EEDEEEDEDSDSGSDEEEGEAEASSSTPATG------VFLKSWVYQPGEDTEEEEDEDSD 406
           +ED+E+DED D   +E++ E EA  +TPA G      V +K+      ED EEE+DED D
Sbjct: 189 DEDDEDDEDDDD-DEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDED-EEEDDEDED 246

Query: 407 TGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAES 466
               ED+ + +                    ED EEEE+E+ +   KE   +     A+ 
Sbjct: 247 DDDDEDDEDDDD-------------------EDDEEEEEEEEEEPVKEAPGKRKKEMAKQ 287

Query: 467 DPHPSHPDQR 476
              P    Q+
Sbjct: 288 KAAPEAKKQK 297



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 50/183 (27%), Positives = 73/183 (39%), Gaps = 39/183 (21%)

Query: 346 PGEDTEEEEDEE--EDEDSDSGSDE-----EEGEAEASSSTPATGV--FLKSWVYQPGED 396
           P E  E+ EDEE  EDE+ DS  +E     ++G+  A++S     V    K  V  P + 
Sbjct: 21  PKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKK 80

Query: 397 TEEEEDEDSDTGSAEDEREAETSASTPPASAFL--KAWVYRPG----------------- 437
                 + +    A+       + +TP        KA V  PG                 
Sbjct: 81  AAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNA 140

Query: 438 --EDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEA 495
             ED++EEED+D   ED+EDD +    E E +P        A  +     P  E E++E 
Sbjct: 141 KKEDSDEEEDDD-SEEDEEDDEDEDEDEDEIEP--------AAMKAAAAAPASEDEDDED 191

Query: 496 AED 498
            ED
Sbjct: 192 DED 194



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 35/160 (21%), Positives = 60/160 (37%), Gaps = 19/160 (11%)

Query: 152 QGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECC---PAVEEEDDEEAVKKE------ 202
           + SD+   ++  E+E   E+E  ++    P+  +     PA E+EDDE+    E      
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202

Query: 203 ----AHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPR 258
                     +  + G K +  V  P + +N A ++   E  +              D  
Sbjct: 203 EDDSEEEAMETTPAKGKKAAKVV--PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDED 260

Query: 259 SWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQ 298
             E    E  EE+EE   +  GK +     Q +AP  + Q
Sbjct: 261 DEE----EEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQ 296



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 28/122 (22%), Positives = 50/122 (40%), Gaps = 3/122 (2%)

Query: 80  EEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFADGQR 139
           EE+ ED     ++ E   +K +++ P +    D+DD    + E         S+    + 
Sbjct: 157 EEDDEDEDEDEDEIEPAAMKAAAAAPAS---EDEDDEDDEDDEDDDDDEEDDSEEEAMET 213

Query: 140 APLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAV 199
            P       + +    KN  E++ EEE   +E+  +         E     EEE++EE V
Sbjct: 214 TPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPV 273

Query: 200 KK 201
           K+
Sbjct: 274 KE 275


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 135/550 (24%), Positives = 205/550 (37%), Gaps = 97/550 (17%)

Query: 29   LSRAWSRLRGLGPL------EPWLVEAVKGAALVEAGLEGEARTPLAIPHTPWGRRPEEE 82
            LS    R  GLGPL      EP L  A+ G+ L E   EGE   P            E  
Sbjct: 1616 LSAFSERTLGLGPLSFTLEDEPALSTAL-GSQLGEEA-EGEEFCPC-----------EAC 1662

Query: 83   AEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFADGQRAPL 142
                  P   + T+G  T   + EA+ L        GE        G+ ++ A G+    
Sbjct: 1663 VRKKVSPMSPKATMGA-TRGPIKEAFDLQQILQRKRGEHTD-----GEAAEVAPGKTHTD 1716

Query: 143  SPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKE 202
              S   RT+QG++   G   ++  GV  +EG +       +R+  P + E + +   ++ 
Sbjct: 1717 PTST--RTVQGAEGGLGPGLSQGPGV--DEGEDGEGSQRLNRDKDPKLGEAEGDAMAQER 1772

Query: 203  AHRTSTSALSPGS--------------KPSTWVSCPGEEENQATE-----DKRTERSKGA 243
              +T  S  S GS              +  T     G E+N   E     D+   +S GA
Sbjct: 1773 EGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGA 1832

Query: 244  RKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKS-- 301
                       + P S    + EA  + +E   +   + E    P++   AQ P+ +   
Sbjct: 1833 EGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQ-PESEDVE 1891

Query: 302  -----WWCQPSDE----------EEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWP 346
                 W  QP  E           + E +++ A E +GE E      P S   +A     
Sbjct: 1892 TPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDE------PESEGAEAQEAEE 1945

Query: 347  GEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSD 406
                 E + + E E  +S   EEE + E S    A  V +++   Q  E   + E ED +
Sbjct: 1946 AAQEAEGQTQPESEVIESQEAEEEAQPE-SEDVEALEVEVET---QEAEGEAQPESEDVE 2001

Query: 407  TGSAEDE-REAETSASTPPASAFLKAWVYRPGEDTEEEEDEDV----------------D 449
               AE E +EAE  A   P S  ++A     GE+ +E E E                  +
Sbjct: 2002 APEAEGEMQEAEEEAQ--PESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPE 2059

Query: 450  SEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCPFRV 509
            +E++  ++E  + EAE + HP   D  A       +P  E+E  EA E  GEA+      
Sbjct: 2060 AEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQP--ESEGVEAPEAEGEAQKAEGIE 2117

Query: 510  AIYVPGEKPP 519
            A    GE  P
Sbjct: 2118 APETEGEAQP 2127



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 106/428 (24%), Positives = 156/428 (36%), Gaps = 48/428 (11%)

Query: 81   EEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGS-QFADGQR 139
            +EAE+   P E  +   L+      EA G          E E    P  +G  Q A+ + 
Sbjct: 1964 QEAEEEAQP-ESEDVEALEVEVETQEAEGEAQP------ESEDVEAPEAEGEMQEAEEEA 2016

Query: 140  APLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDE--- 196
             P S  +     +   K+ GEE  E EG  E +     + P S     P  EEE  E   
Sbjct: 2017 QPESDGV-----EAQPKSEGEEAQEVEG--ETQKTEGDAQPESDGVEAPEAEEEAQEAEG 2069

Query: 197  --EAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTS--VSPRS 252
              +  + EAH  S    +  ++        G E  +A  + +      A +T     P S
Sbjct: 2070 EVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPES 2129

Query: 253  SGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEG 312
             G +    E   GEA  E E     +  +GEA P  +    AQ  +         +E + 
Sbjct: 2130 EGIEAPEAE---GEAQPESEG-VEAQDAEGEAQPESEG-IEAQEAE---------EEAQP 2175

Query: 313  EVKALGAAEKDGEAECPP-CIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEG 371
            E++ + A E +GEA+     I  P A  +A     G +  E E+E + E     + E EG
Sbjct: 2176 ELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEG 2235

Query: 372  EAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKA 431
            EA+  S     G    S     G D + EE  +S +   ED         TPP S     
Sbjct: 2236 EAQPESEGETQGEKKGSPQVSLG-DGQSEEASESSSPVPEDR-------PTPPPSPGGDT 2287

Query: 432  WVYRPGEDTEEEEDEDV---DSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGK 488
               RPG  T           +   K+ +++  LG+  S    S     A  +     P  
Sbjct: 2288 PHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRMYPES 2347

Query: 489  ETEEEEAA 496
             T E+E A
Sbjct: 2348 STSEQEEA 2355



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 108/463 (23%), Positives = 169/463 (36%), Gaps = 71/463 (15%)

Query: 85   DSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATS--VPRGQGSQFAD------ 136
            D G  GE  + L       L EA G     D M  ERE  +       GS+  +      
Sbjct: 1741 DEGEDGEGSQRLNRDKDPKLGEAEG-----DAMAQEREGKTHNSETSAGSELGEAEQEGE 1795

Query: 137  ---------GQRAPLSPSLLIRTLQGSDKNPGEE---------KAEEEGVAEEEGVNKFS 178
                     GQ +    +L      G D++PG+          +AE E   E EGV    
Sbjct: 1796 GISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPE 1855

Query: 179  YPPSHREC-CPAVEEEDDEEA--VKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDK 235
                 +E    A  E +D EA   + EA   S    +P ++        G E  +A ++ 
Sbjct: 1856 AEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEA 1915

Query: 236  RTE-RSKGARKTSVS--PRSSGSDPRSWEYRSGEA---SEEKEEKAHKETGKGEAAPGPQ 289
            + E  S  A +T     P S G++ +  E  + EA   ++ + E    +  + EA P   
Sbjct: 1916 QPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQP--- 1972

Query: 290  SSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEA-ECPPCIPPPSAFLKAWVYWPGE 348
             S   +  +++    +   E + E + + A E +GE  E      P S  ++A     GE
Sbjct: 1973 ESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGE 2032

Query: 349  DTEEEEDEEEDEDSDS-----GSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDE 403
            + +E E E +  + D+     G +  E E EA  +             Q  E     E E
Sbjct: 2033 EAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEV---------QEAEGEAHPESE 2083

Query: 404  DSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEE--EDEDVDSEDKEDDSEAAL 461
            D D   AE E + E+     P +          GE  + E  E  + + E + +      
Sbjct: 2084 DVDAQEAEGEAQPESEGVEAPEAE---------GEAQKAEGIEAPETEGEAQPESEGIEA 2134

Query: 462  GEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEP 504
             EAE +  P      A       +P  E  E + AE+  EA+P
Sbjct: 2135 PEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEE--EAQP 2175



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 44/161 (27%), Positives = 59/161 (36%), Gaps = 30/161 (18%)

Query: 347  GEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSD 406
            GE  +EE  + E+  ++ G  EE  + E +  T   G        Q  E   EE +E   
Sbjct: 1312 GEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEG-------QQEEEAQLEEIEETGG 1364

Query: 407  TGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEE-EDEDVDSEDKEDDSEAALGEAE 465
             G  E+  + E     P             GE  EE  ++E +  E      E  L EA 
Sbjct: 1365 EGLQEEGVQLEEVKEGPEGGL--------QGEALEEGLKEEGLPEEGSVHGQE--LSEAS 1414

Query: 466  SDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCP 506
            S      PD      G G +     +EEEA      AEPCP
Sbjct: 1415 S------PD------GKGSQEDDPVQEEEAGRASASAEPCP 1443



 Score = 33.5 bits (75), Expect = 0.66
 Identities = 50/189 (26%), Positives = 73/189 (38%), Gaps = 48/189 (25%)

Query: 81   EEAEDSGGPGEDRETLGLKTSSSLPEAWGL-------------LDDDDGMYG-EREATSV 126
            EE E++GG G   E + L+     PE  GL             L ++  ++G E    S 
Sbjct: 1357 EEIEETGGEGLQEEGVQLEEVKEGPEG-GLQGEALEEGLKEEGLPEEGSVHGQELSEASS 1415

Query: 127  PRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHREC 186
            P G+GSQ  D    P+            ++  G   A  E     EG  + + PPSH   
Sbjct: 1416 PDGKGSQEDD----PV-----------QEEEAGRASASAE-PCPAEGTEEPTEPPSHL-- 1457

Query: 187  CPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKT 246
                  E D  A    + R S S L PG +     +  G+E  QA      + ++GA + 
Sbjct: 1458 -----SETDPSA----SERQSGSQLEPGLEKPPGATMMGQEHTQA------QPTQGAAER 1502

Query: 247  SVSPRSSGS 255
            S S   S +
Sbjct: 1503 SSSVACSAA 1511


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 75/301 (24%), Positives = 117/301 (38%), Gaps = 40/301 (13%)

Query: 246 TSVSPRSSGSDPRSWEYRSGEASEEKEEKAHK--ETGKGEAAPGPQSSAPAQR------- 296
           +S  P +S  D    +++  E  EE +E+  +  E  +G  A   +      R       
Sbjct: 273 SSPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPL 332

Query: 297 --------PQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCI----PPPSAFLKA--W 342
                   PQL      PS              ++G  E PP +    PPPSA  +    
Sbjct: 333 EELLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQ 392

Query: 343 VYWPGEDTEE----EEDEEEDEDSDSGSDEEEGEAE--------ASSSTPATGVFLKSWV 390
            + P ED EE    EE+ E++ED+ +  ++ EGE +        A     +    L+ + 
Sbjct: 393 PWHPDEDDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQYA 452

Query: 391 --YQPGEDTEEEEDEDS-DTGSAEDEREAETSASTPPA--SAFLKAWVYRPGEDTEEEED 445
             Y PG  + E+EDED  D  S++ E E    A  PP   S+     V    ED E+E  
Sbjct: 453 GAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHS 512

Query: 446 EDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPC 505
           E+ ++       E+   E+E     S  D+      +G       +EE++  D G   P 
Sbjct: 513 EEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSEADAGSGPPT 572

Query: 506 P 506
           P
Sbjct: 573 P 573



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 87/318 (27%), Positives = 116/318 (36%), Gaps = 73/318 (22%)

Query: 191 EEEDDEEAVKKEAHRTSTSALSPGSKPSTWV---SCPGEEENQATEDKRTERSKGARKTS 247
           EEEDDEE ++ E  +    A +   +          P EE  ++   +  E   G    S
Sbjct: 295 EEEDDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLLE---GPSSPS 351

Query: 248 VSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKG-EAAPGPQSSAPAQRPQLKSWWCQP 306
            +P S  SD R          +  EE A +E  +  E  P P  SA  QR + + W    
Sbjct: 352 QTPSSHDSDTR----------DGPEEGAEEEPPQVLEIKPPP--SAVTQRNK-QPWHPDE 398

Query: 307 SDEE---------------------EGEVK---ALGAAEKDGEAECPPCIPPPSAFLKAW 342
            DEE                     EGEV     L    ++GE      +        A 
Sbjct: 399 DDEEFTANEEEAEDEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQ-----YAG 453

Query: 343 VYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEED 402
            Y PG  + E+EDE+E  D++S   E EG  EA              V    ED   EED
Sbjct: 454 AYAPGSGSSEDEDEDE-VDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSED---EED 509

Query: 403 EDSDT-----GSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSE----DK 453
           E S+       SA +E E+E S      S           +  EEEED+D   E      
Sbjct: 510 EHSEEEETSGSSASEESESEESEDAQSQS-----------QADEEEEDDDFGVEYLLARD 558

Query: 454 EDDSEAALGEAESDPHPS 471
           E+ SEA  G     P P+
Sbjct: 559 EEQSEADAGSGPPTPGPT 576



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 77/327 (23%), Positives = 121/327 (37%), Gaps = 63/327 (19%)

Query: 78  RPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMY--GEREATSVPRGQGSQFA 135
           +P+E+ E+     +D ET+ ++      +A     + + +   GE     + R    Q  
Sbjct: 290 QPQEDEEE-----DDEETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLL 344

Query: 136 DGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPS---HRECCPAVEE 192
           +G   P SPS    +     ++  EE AEEE       V +   PPS    R   P   +
Sbjct: 345 EG---PSSPSQTPSSHDSDTRDGPEEGAEEE----PPQVLEIKPPPSAVTQRNKQPWHPD 397

Query: 193 EDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRS 252
           EDDEE    E                   +   EE+ +   D   E S+ AR+  +S   
Sbjct: 398 EDDEEFTANEEEAEDEED-----------TIAAEEQLEGEVDHAMELSELAREGELSMEE 446

Query: 253 SGSDPRSWEYRSGEASEEKEEKAHKET--------GKGEAAPGPQSSAPAQRPQLKSWWC 304
                 +  Y  G  S E E++   +         G  EA   PQ  + +Q   ++    
Sbjct: 447 L-LQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSE 505

Query: 305 QPSDEEEGEVKALGA-AEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEED-EEEDEDS 362
              DE   E +  G+ A ++ E+E                    ED + +   +EE+ED 
Sbjct: 506 DEEDEHSEEEETSGSSASEESESE------------------ESEDAQSQSQADEEEEDD 547

Query: 363 DSG------SDEEEGEAEASSSTPATG 383
           D G       DEE+ EA+A S  P  G
Sbjct: 548 DFGVEYLLARDEEQSEADAGSGPPTPG 574



 Score = 33.5 bits (75), Expect = 0.66
 Identities = 40/159 (25%), Positives = 64/159 (40%), Gaps = 20/159 (12%)

Query: 362 SDSGSDEEEGEAEASSSTPATGVFL--KSWVYQPGEDTEEEEDEDSDTGSAEDEREAETS 419
           S +GS    G + A+SS P     L  +   +QP ED EE+++E  +    ++  +AE  
Sbjct: 258 SKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQ 317

Query: 420 ---------ASTPPASAFLKA----WVYRPGEDTEEEEDEDVDSED--KEDDSEAALGEA 464
                        P    L++     +  P   ++     D D+ D  +E   E      
Sbjct: 318 RREIELLRREGELPLEELLRSLPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVL 377

Query: 465 ESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAE 503
           E  P PS   QR + + W   P ++ EE  A E+  E E
Sbjct: 378 EIKPPPSAVTQR-NKQPW--HPDEDDEEFTANEEEAEDE 413



 Score = 33.5 bits (75), Expect = 0.66
 Identities = 35/145 (24%), Positives = 51/145 (35%), Gaps = 28/145 (19%)

Query: 153 GSDKNPGEEKAEEEGV-AEEEGVNKFSYPPSHRECCPAVEEED---DEEAVKKEAHRTST 208
           GS ++  E++ +      E EG  +   PP       +   ED   DEE    E   TS 
Sbjct: 460 GSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEETSG 519

Query: 209 SALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEAS 268
           S+                    A+E+  +E S+ A+  S +      D    EY      
Sbjct: 520 SS--------------------ASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARDE 559

Query: 269 EEKEEKAHKETGKGEAAPGPQSSAP 293
           E+ E  A    G G   PGP +  P
Sbjct: 560 EQSEADA----GSGPPTPGPTTLGP 580



 Score = 30.4 bits (67), Expect = 5.6
 Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 597  TQAQEELSPCLTPAARARA--WARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVA 654
            + A + L+  L P A  +    A    PPLAP+P L  +  ++ V +S     P+    +
Sbjct: 1577 SSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSS 1636

Query: 655  TPSRSSAAAA 664
            TP  S A+A+
Sbjct: 1637 TPGTSLASAS 1646



 Score = 29.6 bits (65), Expect = 9.5
 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 5/64 (7%)

Query: 607  LTPAAR-----ARAWARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVATPSRSSA 661
            LTPA+      A+  +    PPL P   L+        P+SPV   P       P+ SSA
Sbjct: 1718 LTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSA 1777

Query: 662  AAAA 665
            +  A
Sbjct: 1778 SLLA 1781


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 69.7 bits (169), Expect = 8e-12
 Identities = 50/162 (30%), Positives = 81/162 (50%), Gaps = 20/162 (12%)

Query: 335 PSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPG 394
           P+A +   +   GE+ EEEE+EEE+E+ +   +EEEGE E         +  +  V + G
Sbjct: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEG 452

Query: 395 E-DTEEEEDEDSDTGS----AEDEREAETSA------------STPPASAFLKAWVYRPG 437
           + D++EEE+ED ++ S    AED  +    A            +  P   FL+       
Sbjct: 453 DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGG-EDSD 511

Query: 438 EDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHF 479
            D+EEE+DE+ D ED++DD +    + +  P PS  +  A+F
Sbjct: 512 SDSEEEDDEEEDDEDEDDDDDEE--DGDEVPVPSFGEAMAYF 551



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 44/161 (27%), Positives = 69/161 (42%), Gaps = 17/161 (10%)

Query: 213 PGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKE 272
           P +  +T +   GEEE +  E++  E  +G  +               E   GE  E  E
Sbjct: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE--------EEEGGEGEELGE 444

Query: 273 EKAHKETGKGEAAPGPQSSAPAQRPQLKSW-WCQPSDEEEGEVKALGAAEKDGEAECPPC 331
           E+  +E G  ++    +    +    L++  W Q   E  G   A GA E   EA+CP  
Sbjct: 445 EEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQE---EAQCPTL 501

Query: 332 IPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGE 372
                 FL+       +  EE+++EE+DED D   DEE+G+
Sbjct: 502 -----HFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGD 537


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 81/435 (18%), Positives = 152/435 (34%), Gaps = 38/435 (8%)

Query: 48   EAVKGAALVEAGLEGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEA 107
            E  K  A  ++ ++ EA++P  +      + P +E   S    +  E    K+       
Sbjct: 610  EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP 669

Query: 108  WGLLDDDDGMYGEREATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEG 167
                        + EA S  + +    A+ +    + S +    +  +K     K E + 
Sbjct: 670  V-----------KAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS 718

Query: 168  VAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEE 227
              + +   K       +   P  EE    E  K      +    SP +K       P +E
Sbjct: 719  PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKT------PAKE 772

Query: 228  ENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPG 287
            E ++  DK  E++K   K  V        P   + ++ E    K+E+      + E    
Sbjct: 773  EARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE 832

Query: 288  PQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPG 347
             +   P ++ + +     P  EE+ + K   A +K+         P      +  V  P 
Sbjct: 833  VKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPK------PKVEEKKEPAVEKPK 886

Query: 348  EDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDT 407
            E   E + EE ++     + E+E  A+      A          +P E TE  + E  D 
Sbjct: 887  ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDA----------KPKEKTEVAKKEPDDA 936

Query: 408  GSAEDEREAETSASTPPASAFLKAWVYRPGEDTE-----EEEDEDVDSEDKEDDSEAALG 462
             + E  + AE   + P      +    +P E  +     +E+D+ +  E  +  +E A  
Sbjct: 937  KAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEK 996

Query: 463  EAESDPHPSHPDQRA 477
             + +D   S P ++A
Sbjct: 997  SSSTDQKDSKPPEKA 1011



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 114/520 (21%), Positives = 180/520 (34%), Gaps = 63/520 (12%)

Query: 78  RPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFADG 137
           + EE  E+ GG  E+ E  G + + S P       + +     +E    P    S   + 
Sbjct: 479 KEEEGKEEEGGEEEEAEG-GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537

Query: 138 QRAPL---SPSLLIRTLQGSDKNPGE----EKAEEEGVAEEEGVNKFSYPPSHRECCPAV 190
            ++P    SP       +   K+P E    EK E +  AE +   K   P       PA 
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA- 596

Query: 191 EEEDDEEA---VKKEAHRTSTSALSP---GSKPSTWVSCPGEEENQATED-KRTERSKGA 243
           E +  E+A   VK+EA ++   A SP    +K    V  P + ++   E+ K  E++K  
Sbjct: 597 EAKSPEKAKSPVKEEA-KSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655

Query: 244 RKTSVSPRSSGSDPRSWEYRSGEAS------EEKEEKAHKETGKGEAAPGPQSSAPAQRP 297
            K           P   E +S E +      E K  +  K   K EA    ++ +P +  
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715

Query: 298 QLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEE 357
                  +   +EE +      +    EA+ P     P       V  P   T  +E+  
Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775

Query: 358 EDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAE 417
              D      +   + E  S   A    LK     P ++  ++E+  S     E+E+  E
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEKAKSP-LKEDAKAPEKEIPKKEEVKSPV--KEEEKPQE 832

Query: 418 TSASTPPASAFLKAWVYRPGEDTE------------------EEEDEDVDSEDKEDDSEA 459
                PP  A  +     P  + +                  EE+ E    + KE   EA
Sbjct: 833 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEA 892

Query: 460 ALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAA----EDWGEAEPCPFRVAIYVPG 515
              EAE       P++ A  +       K  E+ E A    +D    EP         P 
Sbjct: 893 KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK-------PA 945

Query: 516 EKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARK 555
           EK     A P      + + K+PE       P+T  KA++
Sbjct: 946 EKKE---AAPEKKDTKEEKAKKPE-----EKPKTEAKAKE 977



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 61/322 (18%), Positives = 113/322 (35%), Gaps = 27/322 (8%)

Query: 348 EDTEEEEDEEEDEDSDSGSDEE-EGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSD 406
           E+ E+E  EEE ++ + G +EE EG  E + S PA              + E +     +
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEA--------ASPEKEAKSPVKEE 523

Query: 407 TGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAES 466
             S  + +  E   +  PA          P ++  +   E    E +E  S A +   E 
Sbjct: 524 AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK 583

Query: 467 DPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPPPWAPPR 526
              P+  + ++          K   +EEA        P           + P    +P +
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK 643

Query: 527 LPLRLQRRLKRPE-TPTHDPD-PETPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQ 584
              +   + K PE      P+  ++P+KA + +  EK      A    P +A  + P ++
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKA-EAKSPEKAKSPVKAEAKSPEKA--KSPVKE 700

Query: 585 LARDRSRFARRITQAQEELSPCLTPA---------ARARAWARLRNPPLAPIPALTQTLP 635
            A+   +    + +  +      +P          A++      ++P  A  P   +TL 
Sbjct: 701 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD 760

Query: 636 SSSVPSSPVQTTPLSQAVATPS 657
                 SP   TP  +   +P+
Sbjct: 761 ----VKSPEAKTPAKEEARSPA 778



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 64/338 (18%), Positives = 115/338 (34%), Gaps = 40/338 (11%)

Query: 227 EENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKG---E 283
           EE Q TE+   E  K A++               E +  E  EE+E +  +E  K    E
Sbjct: 462 EETQVTEEVTEEEEKEAKEE--------------EGKEEEGGEEEEAEGGEEETKSPPAE 507

Query: 284 AAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECP---PCIPPPSAFLK 340
            A  P+  A +   +      +    E+ E K+    +   +A+ P       PP A   
Sbjct: 508 EAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA--- 564

Query: 341 AWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEE 400
                P ++  +   E +  +      +EE ++ A + +P      KS V +  +   E 
Sbjct: 565 ---KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKA---KSPVKEEAKSPAEA 618

Query: 401 EDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAA 460
           +    +   +  E ++   A +P      K     P +    E++E    E  +   +A 
Sbjct: 619 KSPVKEEAKSPAEVKSPEKAKSP-----TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAE 673

Query: 461 LGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPP 520
               E    P   + ++  +       +    E+A     E    P +    V  E   P
Sbjct: 674 AKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733

Query: 521 PWA--PPRLPLRLQRRLKRPE----TPTHDPDPETPLK 552
             A  P +   +   + K PE         P+ +TP K
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAK 771


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 11/123 (8%)

Query: 339 LKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTE 398
           L+   Y  G D E+ E  + +E+ D   DE++ E E + + P  G       Y+  E+ E
Sbjct: 139 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG-------YEEEEEEE 191

Query: 399 EEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSE 458
           EEEDED D    EDE EA +          L   +    +D E+++D   + E++E++ E
Sbjct: 192 EEEDEDED----EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 247

Query: 459 AAL 461
             L
Sbjct: 248 GGL 250



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 35/106 (33%), Positives = 53/106 (50%), Gaps = 25/106 (23%)

Query: 396 DTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKED 455
           D+EEE+DED D    ED+ E E + + PP             E+ EEEE+ED D ++ ED
Sbjct: 157 DSEEEDDEDGD----EDDEEEEENEAGPPEGY---------EEEEEEEEEEDEDEDEDED 203

Query: 456 DSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGE 501
           ++ + LGE E +             G  Y   +E ++EE  +D+ E
Sbjct: 204 EAGSELGEGEEEV------------GLSYLMKEEIQDEEDDDDYVE 237



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 10/70 (14%)

Query: 429 LKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGK 488
           L+   Y  G D E+ E  D + ED ED  E    E E++  P            GY   +
Sbjct: 139 LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE----------GYEEEE 188

Query: 489 ETEEEEAAED 498
           E EEEE  ++
Sbjct: 189 EEEEEEDEDE 198


>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 2 [Homo sapiens]
          Length = 227

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 11/123 (8%)

Query: 339 LKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTE 398
           L+   Y  G D E+ E  + +E+ D   DE++ E E + + P  G       Y+  E+ E
Sbjct: 98  LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG-------YEEEEEEE 150

Query: 399 EEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSE 458
           EEEDED D    EDE EA +          L   +    +D E+++D   + E++E++ E
Sbjct: 151 EEEDEDED----EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 206

Query: 459 AAL 461
             L
Sbjct: 207 GGL 209



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 35/106 (33%), Positives = 53/106 (50%), Gaps = 25/106 (23%)

Query: 396 DTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKED 455
           D+EEE+DED D    ED+ E E + + PP             E+ EEEE+ED D ++ ED
Sbjct: 116 DSEEEDDEDGD----EDDEEEEENEAGPPEGY---------EEEEEEEEEEDEDEDEDED 162

Query: 456 DSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGE 501
           ++ + LGE E +             G  Y   +E ++EE  +D+ E
Sbjct: 163 EAGSELGEGEEEV------------GLSYLMKEEIQDEEDDDDYVE 196



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 10/70 (14%)

Query: 429 LKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGK 488
           L+   Y  G D E+ E  D + ED ED  E    E E++  P            GY   +
Sbjct: 98  LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE----------GYEEEE 147

Query: 489 ETEEEEAAED 498
           E EEEE  ++
Sbjct: 148 EEEEEEDEDE 157


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 60.1 bits (144), Expect = 7e-09
 Identities = 37/123 (30%), Positives = 59/123 (47%), Gaps = 11/123 (8%)

Query: 339 LKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTE 398
           L+   Y  G D E+ E  + +E+ D   DE++ E E + + P  G       Y+  E+ E
Sbjct: 91  LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEG-------YEEEEEEE 143

Query: 399 EEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSE 458
           EEEDED D    EDE EA +          L   +    +D E+++D   + E++E++ E
Sbjct: 144 EEEDEDED----EDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEE 199

Query: 459 AAL 461
             L
Sbjct: 200 GGL 202



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 35/106 (33%), Positives = 53/106 (50%), Gaps = 25/106 (23%)

Query: 396 DTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKED 455
           D+EEE+DED D    ED+ E E + + PP             E+ EEEE+ED D ++ ED
Sbjct: 109 DSEEEDDEDGD----EDDEEEEENEAGPPEGY---------EEEEEEEEEEDEDEDEDED 155

Query: 456 DSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGE 501
           ++ + LGE E +             G  Y   +E ++EE  +D+ E
Sbjct: 156 EAGSELGEGEEEV------------GLSYLMKEEIQDEEDDDDYVE 189



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 22/70 (31%), Positives = 30/70 (42%), Gaps = 10/70 (14%)

Query: 429 LKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGK 488
           L+   Y  G D E+ E  D + ED ED  E    E E++  P            GY   +
Sbjct: 91  LQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE----------GYEEEE 140

Query: 489 ETEEEEAAED 498
           E EEEE  ++
Sbjct: 141 EEEEEEDEDE 150


>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
           [Homo sapiens]
          Length = 531

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 51/160 (31%), Positives = 70/160 (43%), Gaps = 21/160 (13%)

Query: 348 EDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEE---DED 404
           E  EEEE+E E E+ ++G  +EE E  +SS          S     G ++E EE   DE 
Sbjct: 375 EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEG------SEDEHSGSESEREEGDRDEA 428

Query: 405 SD-TGSAEDE-REAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALG 462
           SD +GS EDE  E E  A+      F        G D + E+D D D ED+      +  
Sbjct: 429 SDKSGSGEDESSEDEARAARDKEEIF--------GSDADSEDDADSDDEDRGQAQGGSDN 480

Query: 463 EAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEA 502
           +++S  +      R+H R     P     E  A ED  EA
Sbjct: 481 DSDSGSNGGGQRSRSHSR--SASPFPSGSEHSAQEDGSEA 518



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 26/142 (18%)

Query: 367 DEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEE-EDEDSDTGSAEDEREAETSASTPPA 425
           D  E E EA  +  A    L++  ++P E+ EEE E E+ + G +++E+E  +S+     
Sbjct: 355 DMNEKELEAQEARKAQ---LEN--HEPEEEEEEEMETEEKEAGGSDEEQEKGSSSE---- 405

Query: 426 SAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYR 485
                       ++  E+E    +SE +E D + A  ++ S    S  D+    R     
Sbjct: 406 ------------KEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEI 453

Query: 486 PGKETEEEEAA----EDWGEAE 503
            G + + E+ A    ED G+A+
Sbjct: 454 FGSDADSEDDADSDDEDRGQAQ 475



 Score = 33.1 bits (74), Expect = 0.86
 Identities = 51/234 (21%), Positives = 78/234 (33%), Gaps = 85/234 (36%)

Query: 226 EEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKE---EKAHKETGKG 282
           EEE   TE+K    S   ++   S    GS+    +  SG  SE +E   ++A  ++G G
Sbjct: 380 EEEEMETEEKEAGGSDEEQEKGSSSEKEGSE----DEHSGSESEREEGDRDEASDKSGSG 435

Query: 283 EAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAW 342
           E                         +E  E +A  A +K+                   
Sbjct: 436 E-------------------------DESSEDEARAARDKE------------------- 451

Query: 343 VYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEED 402
                E    + D E+D DSD   DE+ G+A+  S                        D
Sbjct: 452 -----EIFGSDADSEDDADSD---DEDRGQAQGGS------------------------D 479

Query: 403 EDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDD 456
            DSD+GS    + + + + +  AS F     +   ED  E    D    D + D
Sbjct: 480 NDSDSGSNGGGQRSRSHSRS--ASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531


>gi|188219559 protein phosphatase 1, regulatory subunit 15B [Homo
           sapiens]
          Length = 713

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 82/389 (21%), Positives = 142/389 (36%), Gaps = 57/389 (14%)

Query: 266 EASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGE 325
           E++EEK E    E         P    P+    ++       +  EG +  +  +  +G+
Sbjct: 359 ESTEEKIELLTTEVPLALEEESPSEGCPSSEIPMEK------EPGEGRISVVDYSYLEGD 412

Query: 326 AEC---PPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDS-DSGSDEEEGEAEASSSTPA 381
                 P C      ++        E + + E E+ DE++ D G D +   +++      
Sbjct: 413 LPISARPACSNKLIDYILGGASSDLETSSDPEGEDWDEEAEDDGFDSDSSLSDSDLEQDP 472

Query: 382 TGVFLKSWV-----YQPGEDT-----------EEEEDEDSDTGSAEDEREAETSASTPPA 425
            G+ L +       Y P   T           EE  D + D     D   +  S S P  
Sbjct: 473 EGLHLWNSFCSVDPYNPQNFTATIQTAARIVPEEPSDSEKDLSGKSDLENSSQSGSLPET 532

Query: 426 SAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYR 485
                       E +  EED+   S D+ +  +       SD   +  + +A F+  G  
Sbjct: 533 P-----------EHSSGEEDDWESSADEAESLKLWNSFCNSDDPYNPLNFKAPFQTSGEN 581

Query: 486 PGKETEEEEAAEDWGEAEPCPFRVAIYVP--GEKPPPPWAPPRLPLRLQRRLKRPETPTH 543
                + +  +E       C   ++  V   G +          P  +QR +      TH
Sbjct: 582 EKGCRDSKTPSESIVAISECHTLLSCKVQLLGSQES------ECPDSVQRDVLSGGRHTH 635

Query: 544 DPDPETPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQEEL 603
                  +K +KV F E+VT ++++         R+GPWE+ ARD  RF +RI + ++ +
Sbjct: 636 -------VKRKKVTFLEEVTEYYIS-----GDEDRKGPWEEFARDGCRFQKRIQETEDAI 683

Query: 604 SPCLTPAARARAWARLRNPPLAPIPALTQ 632
             CLT   R R + RL+      +  L Q
Sbjct: 684 GYCLTFEHRERMFNRLQGTCFKGLNVLKQ 712


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 89/370 (24%), Positives = 135/370 (36%), Gaps = 68/370 (18%)

Query: 164  EEEGVAEEEGVNKFSYPPSHRECCPAV----EEEDDEEAVKKEAHRTSTSALSPGSKPST 219
            E  G+ E EG+   S    + E         +E+D E+   K   +   +A+   S+   
Sbjct: 4676 EGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEM-SEDFD 4734

Query: 220  WVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGS----DPRSWEYRSGEASEEKEEKA 275
                 GE E Q  +D++++   G     +   +       D R W     E  EE+E+  
Sbjct: 4735 GKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNK 4794

Query: 276  HKETGKG------EAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKD------ 323
             +ETG G      E      +       + KS   +  ++EE E    G  E        
Sbjct: 4795 TEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQID 4854

Query: 324  ----GEAECPPC------IPPPSAF-------LKAWVYWPGEDTEEEEDEEEDEDSDSGS 366
                 E E  P       +P P A        L +     GEDT+ EE EEE+       
Sbjct: 4855 ERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEK 4914

Query: 367  DEEEG-EAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPA 425
             EE G EAE    T               +  +E E+  S+   AE E E +T A     
Sbjct: 4915 PEEAGHEAEERGETETD--------QNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDG 4966

Query: 426  SAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYR 485
             A       +  E+  EE+ + V+ +DKE D E      E+ P     DQ       G++
Sbjct: 4967 DAA------QHPEEHSEEQQQSVEEKDKEADEEG----GENGP----ADQ-------GFQ 5005

Query: 486  PGKETEEEEA 495
            P +E E E++
Sbjct: 5006 PQEEEEREDS 5015



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 113/484 (23%), Positives = 158/484 (32%), Gaps = 136/484 (28%)

Query: 77   RRPEEEAE-DSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFA 135
            +  +EEAE D GG GED      K +  + E     ++ D  +G +E   VP  +     
Sbjct: 4831 KEEKEEAEADDGGQGED------KINEQIDERDYDENEVDPYHGNQE--KVPEPEALDLP 4882

Query: 136  DGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDD 195
            D              L   DKN GE+   EEG  EEE   +    P   E     EE  +
Sbjct: 4883 DDLN-----------LDSEDKNGGEDTDNEEG--EEENPLEIKEKPE--EAGHEAEERGE 4927

Query: 196  EEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEE-----------------------NQAT 232
             E  + E    S S   P   PS      GEEE                        Q+ 
Sbjct: 4928 TETDQNE----SQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSV 4983

Query: 233  EDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEK-----EEKAH----------- 276
            E+K  E  +   +    P   G  P+  E R    +EE+     E K H           
Sbjct: 4984 EEKDKEADEEGGENG--PADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENM 5041

Query: 277  --------------KETGKGE---------AAPGPQSSAPAQ-------RPQLKSWWCQP 306
                          KE GK E          A G +S+  AQ       R   +S+  +P
Sbjct: 5042 QNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKP 5101

Query: 307  S---------DEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVY---------WPGE 348
                      D  E   K L   + D  AE  P   P +    A  +         +  +
Sbjct: 5102 GQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQ 5161

Query: 349  DTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTG 408
              +    E++    DSG D+EE E E +                   DTEE+  E+    
Sbjct: 5162 TYDVASKEQQQSAKDSGKDQEEEEIEDTLM-----------------DTEEQ--EEFKAA 5202

Query: 409  SAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDP 468
              E  +  E  + T     F +  V      TEE++D   D   KE ++E      ES  
Sbjct: 5203 DVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTI 5262

Query: 469  HPSH 472
            H +H
Sbjct: 5263 HTAH 5266



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 56/189 (29%), Positives = 75/189 (39%), Gaps = 46/189 (24%)

Query: 347  GEDTEEEEDEEED---EDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDE 403
            G+D EEE++EEED   E++  G DEE+ E  A      +G   K    Q  ++ E+EE E
Sbjct: 4780 GDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKE-EKEEAE 4838

Query: 404  DSDTGSAED-----------------------EREAETSASTPPASAFLKAWVYRPGEDT 440
              D G  ED                       E+  E  A   P    L +     GEDT
Sbjct: 4839 ADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDT 4898

Query: 441  EEEEDEDVDS-EDKEDDSEAA-----LGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEE 494
            + EE E+ +  E KE   EA       GE E+D + S   Q             E EE  
Sbjct: 4899 DNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQ-------------EPEEGP 4945

Query: 495  AAEDWGEAE 503
            + +D  E E
Sbjct: 4946 SEDDKAEGE 4954



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 81/394 (20%), Positives = 145/394 (36%), Gaps = 89/394 (22%)

Query: 80   EEEAEDSGGPGEDRETLGLKTSSSLP---EAWGLLDDDDGMYGEREATSVPRGQGSQFAD 136
            EE+ ED+   G++++     + S +     A  + +D DG   + E     + +  + +D
Sbjct: 4696 EEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEE--QEEDDEKSD 4753

Query: 137  GQRAPLSPSLLIRTLQGSDKNPGEEKA---EEEGVAEEEGVNKFSYPPSHRECCPAVEEE 193
             +   L   +    L G + +  +E+    ++E   EEE  NK        E  P ++EE
Sbjct: 4754 SEGGDLDKHM--GDLNGEEADKLDERLWGDDDEEEDEEEEDNKTE------ETGPGMDEE 4805

Query: 194  DDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSS 253
            D E   K +   +  S                  ++++ +DK+ E+ +            
Sbjct: 4806 DSELVAKDDNLDSGNS-----------------NKDKSQQDKKEEKEEA----EADDGGQ 4844

Query: 254  GSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSW---WCQPSDEE 310
            G D  + +    +  E + +  H   G  E  P P++        L S      + +D E
Sbjct: 4845 GEDKINEQIDERDYDENEVDPYH---GNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNE 4901

Query: 311  EGEVK-----------ALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEED 359
            EGE +           A   AE+ GE E                  P E   E++  E +
Sbjct: 4902 EGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQE-------PEEGPSEDDKAEGE 4954

Query: 360  EDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETS 419
            E+ D+G+D+++G+A                   P E +EE++    +     DE   E  
Sbjct: 4955 EEMDTGADDQDGDA----------------AQHPEEHSEEQQQSVEEKDKEADEEGGENG 4998

Query: 420  ASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDK 453
               P    F         +  EEEE ED D+E++
Sbjct: 4999 ---PADQGF---------QPQEEEEREDSDTEEQ 5020



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 88/424 (20%), Positives = 149/424 (35%), Gaps = 84/424 (19%)

Query: 61   EGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGE 120
            EGE   PL I       +PEE   ++   GE         S   PE      +DD   GE
Sbjct: 4902 EGEEENPLEIKE-----KPEEAGHEAEERGETETDQNESQSPQEPEEGP--SEDDKAEGE 4954

Query: 121  REATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYP 180
             E  +   G   Q  D  + P   S      Q       +++A+EEG  E    ++   P
Sbjct: 4955 EEMDT---GADDQDGDAAQHPEEHS----EEQQQSVEEKDKEADEEG-GENGPADQGFQP 5006

Query: 181  PSHRECCPAVEEEDDEEAVKKEAHRT--STSALSPGSKPSTWVSCPGEEENQATEDKRT- 237
                E   +  EE   EA++++ H +   T   +  +  +  ++    E+ Q  E+  + 
Sbjct: 5007 QEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSG 5066

Query: 238  ----ERSKGARKTSVSPRSSGSDPR----SWEYRSGEASEEKE-----EKAHKET----- 279
                 +++G     ++  +S    R    S++ + G+A  E+      E+ HK       
Sbjct: 5067 AADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDT 5126

Query: 280  -GKGEAAPGPQSSAP------------------------AQRPQLKSWWCQPSDEEEGEV 314
                E  P  Q  A                         A + Q +S      D+EE E+
Sbjct: 5127 DSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEI 5186

Query: 315  K-ALGAAEKDGE-----------AECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDS 362
            +  L   E+  E            E       P  F +  V      TEE++D   D+ +
Sbjct: 5187 EDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDK-A 5245

Query: 363  DSGSDEEEGEAEASSSTPATGVFLKSWVYQPG-EDTEEEEDE---------DSDTGSAED 412
               ++ E+ E    S+      FL   ++QP  +D  E   E           ++G+ E+
Sbjct: 5246 HKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEE 5305

Query: 413  EREA 416
            E+ A
Sbjct: 5306 EKVA 5309


>gi|157738619 smoothelin-like 1 [Homo sapiens]
          Length = 512

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 65/292 (22%), Positives = 112/292 (38%), Gaps = 30/292 (10%)

Query: 213 PGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKE 272
           PG+   +  S    E+ +  E K +E        + +P  SG    + E + G A +   
Sbjct: 3   PGAVGESDCSAEAREKMEQKEGKLSEDGTTVSPAADNPEMSGGGAPAEETK-GTAGKAIN 61

Query: 273 EKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCI 332
           E    E+GK E AP     +   + +         DE + E +     ++D EAE     
Sbjct: 62  EGPPTESGKQEKAPAEDGMSAELQGEANGL-----DEVKVESQREAGGKEDAEAELKKED 116

Query: 333 PPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQ 392
                         G   E + + +E E+ +S    E+ +AE   + P +G    +    
Sbjct: 117 GEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRD 176

Query: 393 PGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSED 452
             E     E+ED+ T S E+  + +  ++ P                 E+  DE+  +E 
Sbjct: 177 KPEPKATVEEEDAKTASQEETGQRKECSTEPK----------------EKATDEEAKAE- 219

Query: 453 KEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEP 504
               S+ A+ E E+   P  PD +   +   +   +E + +E AED  EAEP
Sbjct: 220 ----SQKAVVEDEAKAEPKEPDGKEEAK---HGAKEEADAKEEAEDAEEAEP 264



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 67/279 (24%), Positives = 110/279 (39%), Gaps = 30/279 (10%)

Query: 155 DKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKE----AHRTSTSA 210
           +K P E+    E   E  G+++     S RE   A  +ED E  +KKE       T  S 
Sbjct: 72  EKAPAEDGMSAELQGEANGLDEVKVE-SQRE---AGGKEDAEAELKKEDGEKEETTVGSQ 127

Query: 211 LSPGSKPSTWVSCPGEEENQAT--EDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEAS 268
              G K  T       EE ++T   +K+    K A+  S   ++  +D    E ++    
Sbjct: 128 EMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPES-GQKADANDRDKPEPKATVEE 186

Query: 269 EEKEEKAHKETG-KGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAE 327
           E+ +  + +ETG + E +  P+  A  +  + +S      DE + E K     E DG+ E
Sbjct: 187 EDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPK-----EPDGKEE 241

Query: 328 CPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLK 387
                   +            D +EE ++ E+ +  S S+E+E + E      A GV   
Sbjct: 242 AKHGAKEEA------------DAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGA-GVIPS 288

Query: 388 SWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPAS 426
           S    P   T E  +  +D    +     +TS S   +S
Sbjct: 289 SPEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESS 327



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 61/242 (25%), Positives = 90/242 (37%), Gaps = 24/242 (9%)

Query: 71  PHTPWGRRPEEEAEDSGGPGEDRETLGLKTSS--SLPEAWGLLDDDDGMY---GEREATS 125
           P T  G++ +  AED        E  GL      S  EA G  D +  +    GE+E T+
Sbjct: 64  PPTESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAGGKEDAEAELKKEDGEKEETT 123

Query: 126 VPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRE 185
           V    GSQ   G++            + S     ++KAEE+    E G    +      E
Sbjct: 124 V----GSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKPE 179

Query: 186 CCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKR--------- 236
               VEEED + A ++E  +    +  P  K +T      E +    ED+          
Sbjct: 180 PKATVEEEDAKTASQEETGQRKECSTEPKEK-ATDEEAKAESQKAVVEDEAKAEPKEPDG 238

Query: 237 TERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQR 296
            E +K   K     +    D    E   G  SEE+E+   KE    E   G   S+P + 
Sbjct: 239 KEEAKHGAKEEADAKEEAEDAE--EAEPGSPSEEQEQDVEKEP---EGGAGVIPSSPEEW 293

Query: 297 PQ 298
           P+
Sbjct: 294 PE 295



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 53/220 (24%), Positives = 91/220 (41%), Gaps = 23/220 (10%)

Query: 80  EEEAEDSGGP---GEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQF-- 134
           E+EA+   G      DR+    K +    +A     ++ G    +E ++ P+ + +    
Sbjct: 159 EKEAKPESGQKADANDRDKPEPKATVEEEDAKTASQEETGQ--RKECSTEPKEKATDEEA 216

Query: 135 -ADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEE 193
            A+ Q+A +         +   K   +  A+EE  A+EE  +         E  P    E
Sbjct: 217 KAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDA-------EEAEPGSPSE 269

Query: 194 DDEEAVKKEAHRTSTSALSPGSKPSTWVSCP-GEEENQATEDKRTERSKGARKTSVSPRS 252
           + E+ V+KE      + + P S P  W   P GE  N +T+    +     + +  +  S
Sbjct: 270 EQEQDVEKEPE--GGAGVIPSS-PEEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASES 326

Query: 253 SGSD-PRSWEYRSGEASEEKEEKAHKETGKGEAAP-GPQS 290
           S SD P+S       +S EK+EKA +      A P GP++
Sbjct: 327 SPSDVPQSPP--ESPSSGEKKEKAPERRVSAPARPRGPRA 364


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 97/426 (22%), Positives = 148/426 (34%), Gaps = 44/426 (10%)

Query: 263 RSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEK 322
           +S   SEEK +   ++  KGE        A A +    S   QP++EEE +         
Sbjct: 205 KSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGS---QPAEEEEDQ--------- 252

Query: 323 DGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPAT 382
                       PS  L+         TEEEE+EEE+E+ D   +E + E + S   P  
Sbjct: 253 ----------ETPSRNLRVRAD-RNLKTEEEEEEEEEEEEDDEEEEGDDEGQKSREAPIL 301

Query: 383 GVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEE 442
             F +     P    EE  DE   T S E E        T       K+ + R  ++ E 
Sbjct: 302 KEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEM 361

Query: 443 EEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAED--WG 500
           +    ++ E++E  S   L E    P P    +          P +   EEE        
Sbjct: 362 KTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTK 421

Query: 501 EAEPCPFRVAIY-----VPGEKPPPP----WAPPRLPLRLQRRLKRPETP--THDPDP-E 548
           EA   P    ++      P E P PP     +PP      +  L    T        P  
Sbjct: 422 EASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLS 481

Query: 549 TPLKARKVRFSEKVTVHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQEELS---- 604
           +P   +    +EKV    +      +  A     + L  +  R A+ +    EEL+    
Sbjct: 482 SPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKG 541

Query: 605 ---PCLTPAARARAWARLRNPPLAPIPALTQTLPSSSVPSSPVQTTPLSQAVATPSRSSA 661
               CL   +  +   R  +  L P   L Q+  SSS  SS   ++       +P  S +
Sbjct: 542 ITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGS 601

Query: 662 AAAAAL 667
            + + L
Sbjct: 602 RSHSPL 607



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 71/292 (24%), Positives = 113/292 (38%), Gaps = 50/292 (17%)

Query: 48  EAVKGAALVEAGLEGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEA 107
           EA + A L EA  E E    +  P       P +       P  +      + SSS+ E 
Sbjct: 155 EAREAAELEEASAESEDE--MIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEE 212

Query: 108 WGLLDDDDGMYGEREATSVPR------GQGSQFADGQRAPLSPSLLIR--------TLQG 153
            G  DD+    GER ++ V +       +GSQ A+ +    +PS  +R        T + 
Sbjct: 213 KGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEE 272

Query: 154 SDKNPGEEKAEEEGVAEEEGVNKFSYP-----PSHRECCPAVEEED----------DEEA 198
            ++   EE+ +EE   ++EG      P         E  P V+ E+           E+ 
Sbjct: 273 EEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQE 332

Query: 199 VKKEAHRTSTSALSPGSKPSTWVSCPGEEENQAT-----EDKRTERSKGARKTSVSPRSS 253
           V +   R + S     ++ S       E+E + T     E++  + S+G ++ S SP   
Sbjct: 333 VLERGGRFTRS--QEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSP--- 387

Query: 254 GSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGP----QSSAPAQRPQLKS 301
            S PR  E R   +     E    +T   E  P P    ++S+P   PQL S
Sbjct: 388 -SPPRLTEDRKKASLVALPE----QTASEEETPPPLLTKEASSPPPHPQLHS 434



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 66/313 (21%), Positives = 106/313 (33%), Gaps = 84/313 (26%)

Query: 117  MYGEREATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNK 176
            ++G +   S P+   + +A+         LL+         P E K EE+G+     ++ 
Sbjct: 1069 LHGVKWPQSNPKFLCADYAEQDELDYHRGLLV-------DRPSETKTEEQGIPRP--LHP 1119

Query: 177  FSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKR 236
               PP      P  E+ + E AV+++                 W     E E +  E  R
Sbjct: 1120 PPPPPVQPPQHPRAEQREQERAVREQ-----------------WAE--REREMERRERTR 1160

Query: 237  TERSKGARKTSVSPRS---SGSDPRSWEYRSGEASEEKEEKAHKET---------GKGEA 284
            +ER     K    PRS   S    R    +S E   EK+EKA +E           K +A
Sbjct: 1161 SEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKA 1220

Query: 285  APGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVY 344
            AP               +W   +D +  + K    AE+  E E                 
Sbjct: 1221 AP-------------CIYWLPLTDSQIVQ-KEAERAERAKERE----------------- 1249

Query: 345  WPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDED 404
               +  +E+E+EE+ E       E   + E            K   +    D E E + +
Sbjct: 1250 ---KRRKEQEEEEQKEREKEAERERNRQLERE----------KRREHSRERDRERERERE 1296

Query: 405  SDTGSAEDEREAE 417
             D G  + +RE +
Sbjct: 1297 RDRGDRDRDRERD 1309


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 77/320 (24%), Positives = 118/320 (36%), Gaps = 78/320 (24%)

Query: 158  PGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKP 217
            PG+++  EE    EEG +   +    +   P     +D+ +  KE  + +   L      
Sbjct: 1197 PGKKRQTEE----EEGKDNHCF----KNADPCRNNMNDDSSNLKEGSKDNPEPLKC---K 1245

Query: 218  STWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHK 277
              W    G +   +   +  ER  G +    +P  +  +P           E+   +  K
Sbjct: 1246 QVWPK--GTKRGLSKWRQNKERKTGFKLNLYTPPETPMEP----------DEQVTVEEQK 1293

Query: 278  ETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAA-----EKDGEAECPPCI 332
            ET +G+ +P P                      E EVK  G A     E   E  C P  
Sbjct: 1294 ETSEGKTSPSPIRI-------------------EEEVKETGEALLPQEENRREETCAPVS 1334

Query: 333  PPPSAFLKAW--VYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWV 390
            P  S   K    +  P E+ EEEE+EEE+E+ + G +EEEG                   
Sbjct: 1335 PNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEG-EEEEG------------------- 1374

Query: 391  YQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDS 450
               G + E++ D     G+   E+E    ++    SA L        ED E   +ED D+
Sbjct: 1375 ---GGNVEKDPD-----GAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDA 1426

Query: 451  EDKEDDSEAALGEAESDPHP 470
            +D EDDS     E E +  P
Sbjct: 1427 DD-EDDSHMESAEVEKEELP 1445



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 75/364 (20%), Positives = 131/364 (35%), Gaps = 49/364 (13%)

Query: 156  KNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTST--SALSP 213
            K   EE+ EEE   EEE   +        E     EEE++EE ++    R +   S    
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEE---EEEEEEEEENIQSSPPRLTKPQSVAIK 1122

Query: 214  GSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEE 273
              +P       G +  +      TE      +    P  +  + R           E EE
Sbjct: 1123 RKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEE 1182

Query: 274  KAHKETGKGEAAPGPQSSAPAQRPQLKSWWC-QPSDEEEGEVKALGAAEKDGEAECPPCI 332
               K   +      P      +  + K   C + +D     +    +  K+G  + P  +
Sbjct: 1183 DGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLKEGSKDNPEPL 1242

Query: 333  PPPSAF-------LKAW-------------VYWPGEDTEEEEDEEEDEDSDSGSDEEEGE 372
                 +       L  W             +Y P E T  E DE+        + EE+ E
Sbjct: 1243 KCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPE-TPMEPDEQV-------TVEEQKE 1294

Query: 373  AEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAW 432
                 ++P+  + ++  V + GE    +E+      +  +E  A  S +T P     +  
Sbjct: 1295 TSEGKTSPSP-IRIEEEVKETGEALLPQEE------NRREETCAPVSPNTSPGEK-PEDD 1346

Query: 433  VYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEE 492
            + +P E+ EEEE+E+ + E++E + E   G  E DP  +   ++         P   TE+
Sbjct: 1347 LIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKE-------EPEISTEK 1399

Query: 493  EEAA 496
            E++A
Sbjct: 1400 EDSA 1403



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 44/177 (24%), Positives = 72/177 (40%), Gaps = 42/177 (23%)

Query: 348  EDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDT 407
            E +EEEE+EE++E+ +   +EEE E E                    E+ EEEE+E+ + 
Sbjct: 1067 ESSEEEEEEEDEEEEEEEEEEEEDEEE--------------------EEEEEEEEEEENI 1106

Query: 408  GSAEDEREAETSASTPPASAFL-------------KAWVYRPGEDTEEEEDEDVDSEDKE 454
             S+        S +      F+              +       +T E  +E  D+ D+E
Sbjct: 1107 QSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEE 1166

Query: 455  DDSE--AALGEAESDPHPSHPDQRAHFRGWGYRPGK--ETEEEEAAED--WGEAEPC 505
                      E E +     P  R  F+   ++PGK  +TEEEE  ++  +  A+PC
Sbjct: 1167 RPMPQLEPTCEIEVEEDGRKPVLRKAFQ---HQPGKKRQTEEEEGKDNHCFKNADPC 1220


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 68/308 (22%), Positives = 113/308 (36%), Gaps = 39/308 (12%)

Query: 160 EEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPST 219
           E+  E E  A E    + S      E CP  E+E +E   K+    + +   S    P  
Sbjct: 435 EDGGEFEEGASENNAKESSPEKEAEEGCP--EKESEEGCPKRGFEGSCSQKESEEGNPVR 492

Query: 220 WVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKET 279
                 EE++   E K+        +  ++  S     +  E   G   E +E+ + KE+
Sbjct: 493 G----SEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES 548

Query: 280 GKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFL 339
              E     QS   ++R + +    +   +EEG  K L     D E E            
Sbjct: 549 D--EDCSEKQSEDGSER-EFEENGLEKDLDEEGSEKELHENVLDKELE------------ 593

Query: 340 KAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEE 399
                    + + E  E ED+ S+   DEE  E E    +       +   Y+   D E 
Sbjct: 594 ---------ENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEE--EEDTYEKVFDDES 642

Query: 400 EEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEA 459
           +E ED +    +    A+  A    A   L        E+++++EDED D ++ ED  E 
Sbjct: 643 DEKEDEEYADEKGLEAADKKAEEGDADEKLF-------EESDDKEDEDADGKEVEDADEK 695

Query: 460 ALGEAESD 467
              + +S+
Sbjct: 696 LFEDDDSN 703



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 52/265 (19%), Positives = 103/265 (38%), Gaps = 42/265 (15%)

Query: 215 SKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEK 274
           SK +   +  G    +  ++K+ E+++   +       + +   S E  + E   EKE +
Sbjct: 409 SKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESE 468

Query: 275 ------------AHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEK 322
                       + KE+ +G    G +  +P +  + K+   +   EE G  K    +E 
Sbjct: 469 EGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKT--LKNDCEENGLAKE---SED 523

Query: 323 DGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPAT 382
           D   E    + P             E  E++ ++E DED      E+  E E   +    
Sbjct: 524 DLNKESEEEVGPTK-----------ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEK 572

Query: 383 GVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEE 442
            +  +    +  E+  ++E E++D+ ++E E +                      E +E 
Sbjct: 573 DLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDE--------------EGSER 618

Query: 443 EEDEDVDSEDKEDDSEAALGEAESD 467
           E DED D +++E+D+   + + ESD
Sbjct: 619 EFDEDSDEKEEEEDTYEKVFDDESD 643



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 69/287 (24%), Positives = 112/287 (39%), Gaps = 40/287 (13%)

Query: 237 TERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEK--EEKAHKETGKGEAAPGPQSSAPA 294
           +ER+  +R    S   S S   + E  +G A EE   E+K  K    GE   G   +   
Sbjct: 391 SERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAK 450

Query: 295 QRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYW-PGEDTEEE 353
           +           S E+E E    G  EK+ E  CP      S   K      P   +EE+
Sbjct: 451 ES----------SPEKEAEE---GCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEED 497

Query: 354 EDEEEDEDSDSGSD-EEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAED 412
             ++E +     +D EE G A+ S         L     +    T+E E++DS+  S ED
Sbjct: 498 SPKKESKKKTLKNDCEENGLAKESEDD------LNKESEEEVGPTKESEEDDSEKESDED 551

Query: 413 --EREAETSASTPPASAFLKAWVYRPGEDTE------EEEDEDVDSEDKE---------D 455
             E+++E  +        L+  +   G + E      ++E E+ DSE+ E          
Sbjct: 552 CSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVL 611

Query: 456 DSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEA 502
           D E +  E + D      ++  + + +     ++ +EE A E   EA
Sbjct: 612 DEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEA 658



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 54/235 (22%), Positives = 92/235 (39%), Gaps = 42/235 (17%)

Query: 261 EYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAA 320
           +Y+  E S E+EE+     G       P+++   +R    S     + E  G  +A   +
Sbjct: 352 DYQVEETSREREERLR---GWEAFLNAPEANRGLRRSDSVS-----ASERAGPSRARHFS 403

Query: 321 EKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAE--ASSS 378
           E            P ++ + A     G   EE  DE++ E ++ G + EEG +E  A  S
Sbjct: 404 EH-----------PSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKES 452

Query: 379 TPATGVFLKSWVYQPGEDTEE-------------EEDEDSD--TGSAEDEREAETSASTP 423
           +P      ++    P +++EE             +E E+ +   GS ED  + E+   T 
Sbjct: 453 SPEK----EAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTL 508

Query: 424 PASAFLKAWVYRPGEDTEEEEDEDV--DSEDKEDDSEAALGEAESDPHPSHPDQR 476
                         +D  +E +E+V    E +EDDSE    E  S+       +R
Sbjct: 509 KNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSER 563


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 68/308 (22%), Positives = 113/308 (36%), Gaps = 39/308 (12%)

Query: 160 EEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPST 219
           E+  E E  A E    + S      E CP  E+E +E   K+    + +   S    P  
Sbjct: 435 EDGGEFEEGASENNAKESSPEKEAEEGCP--EKESEEGCPKRGFEGSCSQKESEEGNPVR 492

Query: 220 WVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKET 279
                 EE++   E K+        +  ++  S     +  E   G   E +E+ + KE+
Sbjct: 493 G----SEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES 548

Query: 280 GKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFL 339
              E     QS   ++R + +    +   +EEG  K L     D E E            
Sbjct: 549 D--EDCSEKQSEDGSER-EFEENGLEKDLDEEGSEKELHENVLDKELE------------ 593

Query: 340 KAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEE 399
                    + + E  E ED+ S+   DEE  E E    +       +   Y+   D E 
Sbjct: 594 ---------ENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEE--EEDTYEKVFDDES 642

Query: 400 EEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEA 459
           +E ED +    +    A+  A    A   L        E+++++EDED D ++ ED  E 
Sbjct: 643 DEKEDEEYADEKGLEAADKKAEEGDADEKLF-------EESDDKEDEDADGKEVEDADEK 695

Query: 460 ALGEAESD 467
              + +S+
Sbjct: 696 LFEDDDSN 703



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 52/265 (19%), Positives = 103/265 (38%), Gaps = 42/265 (15%)

Query: 215 SKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEK 274
           SK +   +  G    +  ++K+ E+++   +       + +   S E  + E   EKE +
Sbjct: 409 SKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESE 468

Query: 275 ------------AHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEK 322
                       + KE+ +G    G +  +P +  + K+   +   EE G  K    +E 
Sbjct: 469 EGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKT--LKNDCEENGLAKE---SED 523

Query: 323 DGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPAT 382
           D   E    + P             E  E++ ++E DED      E+  E E   +    
Sbjct: 524 DLNKESEEEVGPTK-----------ESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEK 572

Query: 383 GVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEE 442
            +  +    +  E+  ++E E++D+ ++E E +                      E +E 
Sbjct: 573 DLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDE--------------EGSER 618

Query: 443 EEDEDVDSEDKEDDSEAALGEAESD 467
           E DED D +++E+D+   + + ESD
Sbjct: 619 EFDEDSDEKEEEEDTYEKVFDDESD 643



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 69/287 (24%), Positives = 112/287 (39%), Gaps = 40/287 (13%)

Query: 237 TERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEK--EEKAHKETGKGEAAPGPQSSAPA 294
           +ER+  +R    S   S S   + E  +G A EE   E+K  K    GE   G   +   
Sbjct: 391 SERAGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAK 450

Query: 295 QRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYW-PGEDTEEE 353
           +           S E+E E    G  EK+ E  CP      S   K      P   +EE+
Sbjct: 451 ES----------SPEKEAEE---GCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEED 497

Query: 354 EDEEEDEDSDSGSD-EEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAED 412
             ++E +     +D EE G A+ S         L     +    T+E E++DS+  S ED
Sbjct: 498 SPKKESKKKTLKNDCEENGLAKESEDD------LNKESEEEVGPTKESEEDDSEKESDED 551

Query: 413 --EREAETSASTPPASAFLKAWVYRPGEDTE------EEEDEDVDSEDKE---------D 455
             E+++E  +        L+  +   G + E      ++E E+ DSE+ E          
Sbjct: 552 CSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVL 611

Query: 456 DSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEA 502
           D E +  E + D      ++  + + +     ++ +EE A E   EA
Sbjct: 612 DEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEA 658



 Score = 34.7 bits (78), Expect = 0.30
 Identities = 54/235 (22%), Positives = 92/235 (39%), Gaps = 42/235 (17%)

Query: 261 EYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAA 320
           +Y+  E S E+EE+     G       P+++   +R    S     + E  G  +A   +
Sbjct: 352 DYQVEETSREREERLR---GWEAFLNAPEANRGLRRSDSVS-----ASERAGPSRARHFS 403

Query: 321 EKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAE--ASSS 378
           E            P ++ + A     G   EE  DE++ E ++ G + EEG +E  A  S
Sbjct: 404 EH-----------PSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKES 452

Query: 379 TPATGVFLKSWVYQPGEDTEE-------------EEDEDSD--TGSAEDEREAETSASTP 423
           +P      ++    P +++EE             +E E+ +   GS ED  + E+   T 
Sbjct: 453 SPEK----EAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTL 508

Query: 424 PASAFLKAWVYRPGEDTEEEEDEDV--DSEDKEDDSEAALGEAESDPHPSHPDQR 476
                         +D  +E +E+V    E +EDDSE    E  S+       +R
Sbjct: 509 KNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSER 563


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 66/314 (21%), Positives = 119/314 (37%), Gaps = 51/314 (16%)

Query: 191  EEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSP 250
            EEED+ E   +E  R  +S           + C    + ++ +++  E S  A  T +  
Sbjct: 1072 EEEDENELFPREYFRRLSS--------QDVLRCQSSSKRKSKDEEEDEESDDADDTPILK 1123

Query: 251  RSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAA-PGPQSSAPAQRPQLK-SWWCQPSD 308
              S    R  +    E       K  K   KG++  P      P ++P  K S    P  
Sbjct: 1124 PVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVS 1183

Query: 309  EEEGEVKALGAAEKDGEA----ECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDS 364
             +   ++ + +  K G      E    + P     K  +  P E  EEEE + E E+++ 
Sbjct: 1184 TQACVIEPIVSIPKAGRKPKIQESEETVEP-----KEDMPLPEERKEEEEMQAEAEEAEE 1238

Query: 365  GSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPP 424
            G +E+   +E  +++PA           P  +T+E E E+ +      E + ++      
Sbjct: 1239 GEEEDAASSEVPAASPADS------SNSPETETKEPEVEEEEEKPRVSEEQRQS------ 1286

Query: 425  ASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGY 484
                             EEE ++++  + E++ +AA   A++D H +  +   H      
Sbjct: 1287 -----------------EEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLES--- 1326

Query: 485  RPGKETEEEEAAED 498
               KE EE+   ED
Sbjct: 1327 TKKKELEEQPTRED 1340


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 66/314 (21%), Positives = 119/314 (37%), Gaps = 51/314 (16%)

Query: 191  EEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSP 250
            EEED+ E   +E  R  +S           + C    + ++ +++  E S  A  T +  
Sbjct: 1072 EEEDENELFPREYFRRLSS--------QDVLRCQSSSKRKSKDEEEDEESDDADDTPILK 1123

Query: 251  RSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAA-PGPQSSAPAQRPQLK-SWWCQPSD 308
              S    R  +    E       K  K   KG++  P      P ++P  K S    P  
Sbjct: 1124 PVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVS 1183

Query: 309  EEEGEVKALGAAEKDGEA----ECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDS 364
             +   ++ + +  K G      E    + P     K  +  P E  EEEE + E E+++ 
Sbjct: 1184 TQACVIEPIVSIPKAGRKPKIQESEETVEP-----KEDMPLPEERKEEEEMQAEAEEAEE 1238

Query: 365  GSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPP 424
            G +E+   +E  +++PA           P  +T+E E E+ +      E + ++      
Sbjct: 1239 GEEEDAASSEVPAASPADS------SNSPETETKEPEVEEEEEKPRVSEEQRQS------ 1286

Query: 425  ASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGY 484
                             EEE ++++  + E++ +AA   A++D H +  +   H      
Sbjct: 1287 -----------------EEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLES--- 1326

Query: 485  RPGKETEEEEAAED 498
               KE EE+   ED
Sbjct: 1327 TKKKELEEQPTRED 1340


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 66/314 (21%), Positives = 119/314 (37%), Gaps = 51/314 (16%)

Query: 191  EEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSP 250
            EEED+ E   +E  R  +S           + C    + ++ +++  E S  A  T +  
Sbjct: 1072 EEEDENELFPREYFRRLSS--------QDVLRCQSSSKRKSKDEEEDEESDDADDTPILK 1123

Query: 251  RSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAA-PGPQSSAPAQRPQLK-SWWCQPSD 308
              S    R  +    E       K  K   KG++  P      P ++P  K S    P  
Sbjct: 1124 PVSLLRKRDVKNSPLEPDTSTPLKKKKGWPKGKSRKPIHWKKRPGRKPGFKLSREIMPVS 1183

Query: 309  EEEGEVKALGAAEKDGEA----ECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDS 364
             +   ++ + +  K G      E    + P     K  +  P E  EEEE + E E+++ 
Sbjct: 1184 TQACVIEPIVSIPKAGRKPKIQESEETVEP-----KEDMPLPEERKEEEEMQAEAEEAEE 1238

Query: 365  GSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPP 424
            G +E+   +E  +++PA           P  +T+E E E+ +      E + ++      
Sbjct: 1239 GEEEDAASSEVPAASPADS------SNSPETETKEPEVEEEEEKPRVSEEQRQS------ 1286

Query: 425  ASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGY 484
                             EEE ++++  + E++ +AA   A++D H +  +   H      
Sbjct: 1287 -----------------EEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLES--- 1326

Query: 485  RPGKETEEEEAAED 498
               KE EE+   ED
Sbjct: 1327 TKKKELEEQPTRED 1340


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 83/351 (23%), Positives = 130/351 (37%), Gaps = 44/351 (12%)

Query: 142 LSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKK 201
           L+ S+     + +++   E +AEEE VA ++   K + P    E     EEE  EE  ++
Sbjct: 480 LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEE 539

Query: 202 EAHRTSTSALSPGS-KPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSW 260
           +    S  A   GS K  +     GE+E   TE    E  +   K          +  + 
Sbjct: 540 DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE-AEAEGEEAEAKEEKKVEEKSEEVATK 598

Query: 261 EYRSGEASEEKEEKAH--------KETGKGEAAPGP---QSSAPAQRPQLKSWWCQPSDE 309
           E    +A  EK EKA         +E GK      P   +  +P  +  ++     P  +
Sbjct: 599 EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 658

Query: 310 EEGEVKALGAAEK---DGEAECP-PCIPPPSAFLKAWVYWPGEDTEEEEDE--------- 356
              E K      K   + +A+ P P  P   A  KA V   GE  EEEE E         
Sbjct: 659 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV-GKGEQKEEEEKEVKEAPKEEK 717

Query: 357 -EEDEDSDSGSDE---------EEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSD 406
            E+ E+      E         EE  AE  + T +  V L+    + G+  ++E++++  
Sbjct: 718 VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKA 777

Query: 407 TGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDS 457
            G    E E     +       +         + E E  E+V+ E KE  S
Sbjct: 778 GGEGGSEEEGSDKGAKGSRKEDIAV-------NGEVEGKEEVEQETKEKGS 821



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 53/234 (22%), Positives = 88/234 (37%), Gaps = 19/234 (8%)

Query: 330 PCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSW 389
           P I   S   K  V  P    + +  EE  E++    ++ E E   ++ T    V +K  
Sbjct: 428 PPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEE 487

Query: 390 VYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEE---EDE 446
             +  E+ EEE + +          E E +A   P  A         GE  EEE   E+E
Sbjct: 488 KKEAAEEKEEEPEAE----------EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE 537

Query: 447 DVDSEDKEDDSEAALGEAESDPHPSHPDQ-RAHFRGWGYRPGKETEEEEAAEDWGEAEPC 505
           + D   K D +E    E E        +Q              E +EE+  E+  E    
Sbjct: 538 EEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 597

Query: 506 PFRVAIYVPGEKPPPPWAP-PRLPLRLQRRLKRPETPTHD----PDPETPLKAR 554
              +      EKP    +P P+ P+  + +   P++P  +    P P++P++ +
Sbjct: 598 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 81/358 (22%), Positives = 134/358 (37%), Gaps = 50/358 (13%)

Query: 160 EEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPST 219
           EE  EE  V +E+   + +      E   +++EE  E A +KE    +        K   
Sbjct: 454 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 513

Query: 220 WVSCP------GEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEE 273
             + P      GE+E +  +++  E  +GA+  S      GS+         E S EKEE
Sbjct: 514 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAK--SDQAEEGGSEK--------EGSSEKEE 563

Query: 274 KAHKETGKGEA-APGPQSSAPAQRPQLKSWWCQPSDEE---EGEVKALGAAEKDGEAECP 329
              +E G+ EA A G ++ A  ++        +   EE   + E+ A    EK  +A+ P
Sbjct: 564 -GEQEEGETEAEAEGEEAEAKEEKK------VEEKSEEVATKEELVADAKVEKPEKAKSP 616

Query: 330 PCIPP-----PSAFLKAWVYWPGEDTEEEEDEEEDEDS--DSGSDEEEGEAEASSSTPAT 382
               P      S   K+ V   G+    +   EE   S       EE+G++  S S    
Sbjct: 617 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP--- 673

Query: 383 GVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEE 442
            V  K+    P    EE + + ++ G  E + E E      P             E  E+
Sbjct: 674 -VEEKAKSPVPKSPVEEAKSK-AEVGKGEQKEEEEKEVKEAPKE-----------EKVEK 720

Query: 443 EEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWG 500
           +E++  D  +K+        EA ++        + H        GK  ++E+  E  G
Sbjct: 721 KEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAG 778



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 74/331 (22%), Positives = 108/331 (32%), Gaps = 76/331 (22%)

Query: 80  EEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFADGQR 139
           EEE ED G   +  E  G +   S                E+E      G+    A+G+ 
Sbjct: 535 EEEEEDEGAKSDQAEEGGSEKEGS---------------SEKEEGEQEEGETEAEAEGEE 579

Query: 140 APLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVN-KFSYPPSHRECCPA--VEEEDDE 196
           A           +  ++   EEK+EE    EE   + K   P   +   P   VEE+   
Sbjct: 580 A-----------EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 628

Query: 197 EAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSP---RSS 253
              K        S +            P EE+ ++   K     KG    S SP   ++ 
Sbjct: 629 PVPKSPVEEKGKSPVPKS---------PVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAK 679

Query: 254 GSDPRS--------WEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQ 305
              P+S         E   GE  EE EEK  KE  K E     +   P   P+ K     
Sbjct: 680 SPVPKSPVEEAKSKAEVGKGEQKEE-EEKEVKEAPKEEKVEKKEEK-PKDVPEKKKAESP 737

Query: 306 PSDEEEGEVKALGAAEK-------------------------DGEAECPPCIPPPSAFLK 340
             +E   EV  +  + K                         +G +E            K
Sbjct: 738 VKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRK 797

Query: 341 AWVYWPGEDTEEEEDEEEDEDSDSGSDEEEG 371
             +   GE   +EE E+E ++  SG +EE+G
Sbjct: 798 EDIAVNGEVEGKEEVEQETKEKGSGREEEKG 828


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 83/351 (23%), Positives = 130/351 (37%), Gaps = 44/351 (12%)

Query: 142 LSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKK 201
           L+ S+     + +++   E +AEEE VA ++   K + P    E     EEE  EE  ++
Sbjct: 104 LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEE 163

Query: 202 EAHRTSTSALSPGS-KPSTWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSW 260
           +    S  A   GS K  +     GE+E   TE    E  +   K          +  + 
Sbjct: 164 DEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETE-AEAEGEEAEAKEEKKVEEKSEEVATK 222

Query: 261 EYRSGEASEEKEEKAH--------KETGKGEAAPGP---QSSAPAQRPQLKSWWCQPSDE 309
           E    +A  EK EKA         +E GK      P   +  +P  +  ++     P  +
Sbjct: 223 EELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 282

Query: 310 EEGEVKALGAAEK---DGEAECP-PCIPPPSAFLKAWVYWPGEDTEEEEDE--------- 356
              E K      K   + +A+ P P  P   A  KA V   GE  EEEE E         
Sbjct: 283 SPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEV-GKGEQKEEEEKEVKEAPKEEK 341

Query: 357 -EEDEDSDSGSDE---------EEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSD 406
            E+ E+      E         EE  AE  + T +  V L+    + G+  ++E++++  
Sbjct: 342 VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKA 401

Query: 407 TGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDS 457
            G    E E     +       +         + E E  E+V+ E KE  S
Sbjct: 402 GGEGGSEEEGSDKGAKGSRKEDIAV-------NGEVEGKEEVEQETKEKGS 445



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 53/234 (22%), Positives = 88/234 (37%), Gaps = 19/234 (8%)

Query: 330 PCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSW 389
           P I   S   K  V  P    + +  EE  E++    ++ E E   ++ T    V +K  
Sbjct: 52  PPITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEE 111

Query: 390 VYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEE---EDE 446
             +  E+ EEE + +          E E +A   P  A         GE  EEE   E+E
Sbjct: 112 KKEAAEEKEEEPEAE----------EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE 161

Query: 447 DVDSEDKEDDSEAALGEAESDPHPSHPDQ-RAHFRGWGYRPGKETEEEEAAEDWGEAEPC 505
           + D   K D +E    E E        +Q              E +EE+  E+  E    
Sbjct: 162 EEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 221

Query: 506 PFRVAIYVPGEKPPPPWAP-PRLPLRLQRRLKRPETPTHD----PDPETPLKAR 554
              +      EKP    +P P+ P+  + +   P++P  +    P P++P++ +
Sbjct: 222 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 275



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 81/358 (22%), Positives = 134/358 (37%), Gaps = 50/358 (13%)

Query: 160 EEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPST 219
           EE  EE  V +E+   + +      E   +++EE  E A +KE    +        K   
Sbjct: 78  EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 137

Query: 220 WVSCP------GEEENQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEE 273
             + P      GE+E +  +++  E  +GA+  S      GS+         E S EKEE
Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAK--SDQAEEGGSEK--------EGSSEKEE 187

Query: 274 KAHKETGKGEA-APGPQSSAPAQRPQLKSWWCQPSDEE---EGEVKALGAAEKDGEAECP 329
              +E G+ EA A G ++ A  ++        +   EE   + E+ A    EK  +A+ P
Sbjct: 188 -GEQEEGETEAEAEGEEAEAKEEKK------VEEKSEEVATKEELVADAKVEKPEKAKSP 240

Query: 330 PCIPP-----PSAFLKAWVYWPGEDTEEEEDEEEDEDS--DSGSDEEEGEAEASSSTPAT 382
               P      S   K+ V   G+    +   EE   S       EE+G++  S S    
Sbjct: 241 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSP--- 297

Query: 383 GVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEE 442
            V  K+    P    EE + + ++ G  E + E E      P             E  E+
Sbjct: 298 -VEEKAKSPVPKSPVEEAKSK-AEVGKGEQKEEEEKEVKEAPKE-----------EKVEK 344

Query: 443 EEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWG 500
           +E++  D  +K+        EA ++        + H        GK  ++E+  E  G
Sbjct: 345 KEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAG 402



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 74/331 (22%), Positives = 108/331 (32%), Gaps = 76/331 (22%)

Query: 80  EEEAEDSGGPGEDRETLGLKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFADGQR 139
           EEE ED G   +  E  G +   S                E+E      G+    A+G+ 
Sbjct: 159 EEEEEDEGAKSDQAEEGGSEKEGS---------------SEKEEGEQEEGETEAEAEGEE 203

Query: 140 APLSPSLLIRTLQGSDKNPGEEKAEEEGVAEEEGVN-KFSYPPSHRECCPA--VEEEDDE 196
           A           +  ++   EEK+EE    EE   + K   P   +   P   VEE+   
Sbjct: 204 A-----------EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 252

Query: 197 EAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATEDKRTERSKGARKTSVSP---RSS 253
              K        S +            P EE+ ++   K     KG    S SP   ++ 
Sbjct: 253 PVPKSPVEEKGKSPVPKS---------PVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAK 303

Query: 254 GSDPRS--------WEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQ 305
              P+S         E   GE  EE EEK  KE  K E     +   P   P+ K     
Sbjct: 304 SPVPKSPVEEAKSKAEVGKGEQKEE-EEKEVKEAPKEEKVEKKEEK-PKDVPEKKKAESP 361

Query: 306 PSDEEEGEVKALGAAEK-------------------------DGEAECPPCIPPPSAFLK 340
             +E   EV  +  + K                         +G +E            K
Sbjct: 362 VKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRK 421

Query: 341 AWVYWPGEDTEEEEDEEEDEDSDSGSDEEEG 371
             +   GE   +EE E+E ++  SG +EE+G
Sbjct: 422 EDIAVNGEVEGKEEVEQETKEKGSGREEEKG 452


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 98/444 (22%), Positives = 151/444 (34%), Gaps = 80/444 (18%)

Query: 241  KGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAPAQRPQLK 300
            K    + +S  S    PR       +  + ++EK   E G+    P P+      + Q K
Sbjct: 896  KRKEPSEISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKP-PKRDEERGKTQGK 954

Query: 301  SWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDE 360
                   D E  E     ++EKD E +                    ED E+E+ EE  +
Sbjct: 955  HRKSFALDSEGEEASQESSSEKDEEDD-------------------EEDEEDEDREEAVD 995

Query: 361  DSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSA 420
             +   ++  +GE E S S+    ++          D++ E D  SD+ S+     + +S+
Sbjct: 996  TTKKETEVSDGEDEESDSSSKCSLY---------ADSDGENDSTSDSESSSSSSSSSSSS 1046

Query: 421  STPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFR 480
            S+  +S+            + E   ED    ++E++  AAL  A   P        A   
Sbjct: 1047 SSSSSSS---------SSSSSESSSED----EEEEERPAALPSASPPPREVPVPTPAPVE 1093

Query: 481  GWGYRPGKETEEEEAAEDWGEAEPCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPET 540
                 P  E           E E  P R A        P   +PP  PLR       P  
Sbjct: 1094 ----VPVPERVAGSPVTPLPEQEASPARPA-------GPTEESPPSAPLRPPEPPAGPPA 1142

Query: 541  PTHDPD--PETPLKARKVRFSEKVTVHFLAVW---------AGPAQAARQGPWEQLA-RD 588
            P   PD  P +P+         + TV F A+          A P QA   GP  + A R 
Sbjct: 1143 PAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRG 1202

Query: 589  RSRFARRITQAQEELSPC----LTPAARARAWARLRNPPLAPIPALTQTLPSSSVPSSPV 644
              R  R +      L       ++   R+RA  R R            T    + P + V
Sbjct: 1203 VERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGR-----------LTEEEEAEPGTEV 1251

Query: 645  QTTPLSQAVATPSRSSAAAAAALD 668
                L+    TP+R    A  A++
Sbjct: 1252 DLAVLADLALTPARRGLPALPAVE 1275



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 89/395 (22%), Positives = 131/395 (33%), Gaps = 113/395 (28%)

Query: 170  EEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEEN 229
            E   +++ S     R   PA E+EDD E  +KEA         PG+KP            
Sbjct: 899  EPSEISEASEEKRPRPSTPAEEDEDDPEQ-EKEAGEPG----RPGTKP------------ 941

Query: 230  QATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQ 289
                D+   +++G  + S +  S G      E  S E+S EK+E+  +E           
Sbjct: 942  -PKRDEERGKTQGKHRKSFALDSEG------EEASQESSSEKDEEDDEE----------- 983

Query: 290  SSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYWPGED 349
                              +E+E   +A+   +K+ E                     GED
Sbjct: 984  -----------------DEEDEDREEAVDTTKKETEVS------------------DGED 1008

Query: 350  TEEEEDE------EEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDE 403
             E +         + D ++DS SD E   + +SSS+ ++              +      
Sbjct: 1009 EESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSS-------------SSSSSSSS 1055

Query: 404  DSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKEDDSEAALGE 463
             S   S+EDE E E  A+ P AS         P  +        V+    E         
Sbjct: 1056 SSSESSSEDEEEEERPAALPSASP--------PPREVPVPTPAPVEVPVPE--------R 1099

Query: 464  AESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCPFRVA-IYVPGEKP--PP 520
                P    P+Q A       RP   TEE   +      EP     A    P E+P  P 
Sbjct: 1100 VAGSPVTPLPEQEAS----PARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPI 1155

Query: 521  PWAPPRLPLRLQRRLKRPE-TPTHDPDPETPLKAR 554
            P  PP    R        E  P  +P P TP +A+
Sbjct: 1156 PLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAK 1190



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 59/238 (24%), Positives = 87/238 (36%), Gaps = 37/238 (15%)

Query: 112  DDDDGMYGEREATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGVAEE 171
            +D+D    E+EA       G     G + P       +T QG  +      +E E  ++E
Sbjct: 920  EDEDDPEQEKEA-------GEPGRPGTKPPKRDEERGKT-QGKHRKSFALDSEGEEASQE 971

Query: 172  EGVNKFSYPPSHRECCPAVEEEDDEEAV---KKEAHRTSTSALSPGSKPSTWVSCPGEEE 228
                K        E     E+ED EEAV   KKE   +        S     +    + E
Sbjct: 972  SSSEKDEEDDEEDE-----EDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGE 1026

Query: 229  NQATEDKRTERSKGARKTSVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGP 288
            N +T D  +  S  +  +S S  SS S        S E+S E EE+  +      A+P P
Sbjct: 1027 NDSTSDSESSSSSSSSSSSSSSSSSSSSS-----SSSESSSEDEEEEERPAALPSASPPP 1081

Query: 289  Q-----SSAPAQRPQLKSWWCQP----SDEEEGEVKALGAAEKDGEAECPPCIP--PP 335
            +     + AP + P  +     P     ++E    +  G  E     E PP  P  PP
Sbjct: 1082 REVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTE-----ESPPSAPLRPP 1134



 Score = 33.9 bits (76), Expect = 0.50
 Identities = 42/168 (25%), Positives = 52/168 (30%), Gaps = 42/168 (25%)

Query: 396 DTEEEEDEDS------DTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVD 449
           DTEEEE+  S      DTGS           + PPA A                     +
Sbjct: 509 DTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPA---------------------N 547

Query: 450 SEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAEPCPFRV 509
            ED         G     P  +  +Q +        P    ++ E ++D     P P   
Sbjct: 548 FEDVAPTGSGEPGATRESPKANGQNQAS--------PCSSGDDMEISDDDRGGSPPPAPT 599

Query: 510 AIYVPGEKPPPPWAPP----RLPLRL---QRRLKRPETPTHDPDPETP 550
               P   PPPP  PP     LPL     Q     P  P   P PE P
Sbjct: 600 PPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRPDGPPPPEYP 647



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 15/89 (16%)

Query: 286  PGPQSSAPAQRPQLKSWWCQPSDE--EEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWV 343
            P P    P   P   + +  P+DE  E  EV    A E           P P    +   
Sbjct: 1311 PAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEE-----------PKPQQLQQQRE 1359

Query: 344  YWPGEDTEEEEDEEEDEDSDSGSDEEEGE 372
               GE+  EEE EEE+E+S   S   +GE
Sbjct: 1360 --EGEEEGEEEGEEEEEESSDSSSSSDGE 1386



 Score = 30.4 bits (67), Expect = 5.6
 Identities = 11/36 (30%), Positives = 23/36 (63%)

Query: 348  EDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATG 383
            +  +++ +E E+E  + G +EEE  +++SSS+   G
Sbjct: 1352 QQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEG 1387


>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
          Length = 352

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 72/277 (25%), Positives = 103/277 (37%), Gaps = 31/277 (11%)

Query: 58  AGLEGEARTPLAIPHTP--WGRRP--EEEAEDSGGPGEDRETLGLKTSSSLP--EAWGLL 111
           AG EG AR    +P  P  W  R   E  A + G    D    G       P   + G  
Sbjct: 7   AGEEGGAREGRLLPRAPGAWVLRACAERAALEVGAASADTGVRGCGARGPAPLLASAGGG 66

Query: 112 DDDDGMYGER---EATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGEEKAEEEGV 168
              DG +G R      ++P    S+ A    A  SP L +   +G    P   +A   G 
Sbjct: 67  RARDGTWGVRTKGSGAALPSRPASRAAPRPEAS-SPPLPLEKARGGLSGPQGGRAR--GA 123

Query: 169 AEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEE 228
               G  K S   S          E  ++  +K+  R  +++ S G K ST    PG EE
Sbjct: 124 MAHVGSRKRSRSRSRSR---GRGSEKRKKKSRKDTSRNCSASTSQGRKAST---APGAEE 177

Query: 229 NQATEDKRTERSKGARKTSVSPRSSGSDPRS-----------WEYRSGEASEEKEEKAHK 277
               + +R  RS  +  +S S  SS S   S            +Y+     ++K+ K  K
Sbjct: 178 RSKQKARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLK 237

Query: 278 ETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEV 314
           + GK +A      + P   P L  W     +EE+G V
Sbjct: 238 KKGKEKAEAQQVEALPG--PSLDQWHRSAGEEEDGPV 272


>gi|119220598 apolipoprotein B48 receptor [Homo sapiens]
          Length = 1088

 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 111/505 (21%), Positives = 172/505 (34%), Gaps = 98/505 (19%)

Query: 55  LVEAGLEGEARTPLAIPHTPWGRRPEEEAEDSGGPGEDRETLGLKTSSSLPEA-WGLLDD 113
           + E   +GEA     +  TP  R PEEE       GE+ E    +TS  L    WG L  
Sbjct: 496 VAELPSDGEAEGTADLEATPEAR-PEEELT-----GEESEAA--QTSCGLLGVEWGGLTH 547

Query: 114 DDGMYGEREATSVPRGQGSQFADGQRAPLSPSLLIRTLQGSDKNPGE---------EKAE 164
                      SV +GQG +   G + P        T Q  ++  GE          K E
Sbjct: 548 -----------SVTKGQGPELMGGAQTP--------TKQPEEREAGEVELMGVLALSKEE 588

Query: 165 EEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCP 224
           +E   E    +  S  P   E  P   E       +K+  R +T   +   +        
Sbjct: 589 QERSLEAGPRHAGSVKPEASEAFPGAWEN----RTRKDMERGNTQEDAADGEQR------ 638

Query: 225 GEEENQATEDKRTERSKGARKTSVS--PRSSGSDPRSWEY----RSGEASEEKEEKAHKE 278
            EEE  A        ++G R++ +S  P + G    + +       GEAS  + ++    
Sbjct: 639 -EEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEASVSENQELDGS 697

Query: 279 TGKGEAAPGPQ-----------SSAPAQRPQLKSWWCQP-----SDEEEGEVKALGAAEK 322
           TG  +A P P              A A R   + W  Q       D E+ +  ++ A   
Sbjct: 698 TG-ADAGPCPSLGEAYARETEDEEAEADRTSRRGWRLQAVAVGLPDREDAQTGSVAAGIM 756

Query: 323 DGEAECPPCIPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPAT 382
            G+   P      +      V   G D++E+E+    E +  G  E   E  A       
Sbjct: 757 GGDV-VPHISAAGAGEALEGVLGQGWDSKEKEEAAAGEHA--GGQEFGLEGSAEEEVTGR 813

Query: 383 GVFLKSWVYQPG---------EDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWV 433
           G  ++++  + G         E++   ED      +      AE   +   A   L+ W 
Sbjct: 814 GSQVEAFESREGGPWGGRVEAEESAGAEDSCGLDPAGSQTARAEGMGAMVEAGGLLEKWT 873

Query: 434 YRPGE-----DTEEEEDEDVDSEDKEDDSEA----------ALGEAESDPHPSHPDQRAH 478
               E     + E+ ED +    D   + EA            G   ++   + P+   H
Sbjct: 874 LLEEEAVGWQEREQREDSEGRCGDYHPEGEAPRLLDAEGLMVTGGRRAEAKETEPESLEH 933

Query: 479 FRGWGYRPGKETEEEEAAEDWGEAE 503
            RG   +P  +   E A E  GEAE
Sbjct: 934 VRGQEEQPTHQAPAEAAPESVGEAE 958



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 110/467 (23%), Positives = 155/467 (33%), Gaps = 99/467 (21%)

Query: 81  EEAEDSGGPGEDRETLG----LKTSSSLPEAWGLLDDDDGMYGEREATSVPRGQGSQFAD 136
           EEAE + G GE+ ET        T+S   EA      + G     E      G    +  
Sbjct: 308 EEAETASG-GEEAETASGGEEAGTASGGEEAGIASGGEAGTASGGEEAGTASGGDEAWTT 366

Query: 137 GQRAPLSPSLLIRTLQGSDKNPGEEKAEEEG---VAEEEGVNKFSYPPSHRECCPAV--E 191
             +       + +T  G+   PGE   E  G   V EEEG  +     S     P V   
Sbjct: 367 SGKEEADLLGVRQTEYGAV--PGERLLEATGKVWVLEEEGDEEREAEVSPFPKQPQVLGT 424

Query: 192 EEDDEEAVKKEAHRTSTSALSPGSKPSTWVSCPGEEENQATE-----DKRTERSKGARKT 246
           E  +E A  + A R +      G      V   G+E     +     D+         + 
Sbjct: 425 ERTEEAAESQTAGREAVGGQEAGESFEGQVDLRGKEAEMRQDLGIRADRARMEELVQAEE 484

Query: 247 SVSPRSSGSDPRSWEYRSGEASEEKEEKAHKETGKGEAAPGPQSSAP------------- 293
           +   R S  DP +     GEA    + +A  E    E   G +S A              
Sbjct: 485 AQEERGSSRDPVAELPSDGEAEGTADLEATPEARPEEELTGEESEAAQTSCGLLGVEWGG 544

Query: 294 -------AQRPQL----KSWWCQPSDEEEGEVKALGAA-----EKDGEAECPP----CIP 333
                   Q P+L    ++   QP + E GEV+ +G       E++   E  P     + 
Sbjct: 545 LTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVLALSKEEQERSLEAGPRHAGSVK 604

Query: 334 PPS--AFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVY 391
           P +  AF  AW     +D E    +E+  D                              
Sbjct: 605 PEASEAFPGAWENRTRKDMERGNTQEDAAD------------------------------ 634

Query: 392 QPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSE 451
             GE  EEEE     T +AE E + E+  S  P +          G  TEE E     SE
Sbjct: 635 --GEQREEEETAGGQTLAAEAEGDRESELSEVPEAGGEGLTTQDAGCGTEEGEAS--VSE 690

Query: 452 DKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAED 498
           ++E D       A++ P PS           G    +ETE+EEA  D
Sbjct: 691 NQELDGSTG---ADAGPCPS----------LGEAYARETEDEEAEAD 724


>gi|153791492 eukaryotic translation initiation factor 3, subunit
           C-like [Homo sapiens]
          Length = 914

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 12/132 (9%)

Query: 348 EDTEEEEDEEEDEDSDSGSDEEEGEAEASSST----------PATGVFLKSWVYQPGEDT 397
           E + +E+ E+ +EDS+  SDE+E E   S++T            +  FLK    +  +  
Sbjct: 164 EQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSE 223

Query: 398 EEEEDEDSDTG--SAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDSEDKED 455
           + E+DED DTG  S++ + E E    T  AS FLK       +    E+  +  ++ K D
Sbjct: 224 DSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHD 283

Query: 456 DSEAALGEAESD 467
                L E E +
Sbjct: 284 RKSKRLDEEEEE 295



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 45/164 (27%), Positives = 66/164 (40%), Gaps = 32/164 (19%)

Query: 288 PQSSAP--AQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYW 345
           P+ SA   A++ +  S      DE+E  V A    +K  EA        PS   + ++  
Sbjct: 163 PEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEA--------PSGESRKFLKK 214

Query: 346 PGEDTEEEEDEEEDEDSDSG--SDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDE 403
             ++ E+ ED E+DED D+G  S + + E E    T     FLK           +    
Sbjct: 215 MDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLK-----------KAPTT 263

Query: 404 DSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDED 447
           D D  +AE +RE +        S  L         D EEEED +
Sbjct: 264 DEDKKAAEKKREDKAKKKHDRKSKRL---------DEEEEEDNE 298


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 73/338 (21%), Positives = 121/338 (35%), Gaps = 57/338 (16%)

Query: 344  YWPGEDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKS----------WVYQP 393
            + PG + EEEE+EE +E+ +   DEEE E+  + +     V   +          W +  
Sbjct: 987  FGPGNEEEEEEEEEYEEEEEEDYDEEEEESSEAGNQRLQQVMHAADPLEIQADVHWTHIR 1046

Query: 394  GEDTEEE---EDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDS 450
              + EE      E S +G+  DE + E    + PA    +A       DT  E D+D   
Sbjct: 1047 EREEEERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQHW 1106

Query: 451  EDKEDDSEAAL-------GEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEAE 503
             D   D++  L       GEAE +   S  +++         P     +E          
Sbjct: 1107 SDSPSDADRELRLPCPAEGEAELELRVSEDEEKL--------PASPKHQERGPSQATSPI 1158

Query: 504  PCPFRVAIYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKVRFSEKVT 563
              P   A+       P    P   P+    + K PE     P+P  P +  K      + 
Sbjct: 1159 RSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLF-PEPLLPKEKPKADAPSDLK 1217

Query: 564  VHFLAVWAGPAQAARQGPWEQLARDRSRFARRITQAQEELSPCLTPAARARAWARLRNPP 623
                 + + P                      + +A+  +SP    + + +       PP
Sbjct: 1218 AVHSPIRSQPV--------------------TLPEARTPVSP---GSPQPQPPVAASTPP 1254

Query: 624  LAPIPALTQTLPS--SSVPS---SPVQTTPLSQAVATP 656
             +P+P  +Q  PS  ++VPS   SP++  P     +TP
Sbjct: 1255 PSPLPICSQPQPSTEATVPSPTQSPIRFQPAPAKTSTP 1292



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 114/515 (22%), Positives = 174/515 (33%), Gaps = 110/515 (21%)

Query: 160  EEKAEEEGVAEEEGVNKFSYPPSHRECCPAVEEEDDEEAVK--KEAHRTSTSALSPGSKP 217
            E + EEEG  EEE       PPS     P  E       +K   E    ++ +  PG++ 
Sbjct: 937  ESEMEEEGEEEEEEPR---LPPSDLGGVPWKEAVRIHALLKGKSEEELEASKSFGPGNEE 993

Query: 218  STWVSCPGEEENQATEDKRTERSKGARKTSVSPRSSGSDPRS------WEYRSGEASEEK 271
                    EEE +   D+  E S  A    +      +DP        W +      EE+
Sbjct: 994  EEEEEEEYEEEEEEDYDEEEEESSEAGNQRLQQVMHAADPLEIQADVHWTHIREREEEER 1053

Query: 272  EEKAHKETGKGEAAPGPQSSAPAQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPC 331
               A + +  G         AP     L+    +  D E  E++  G A +DG+      
Sbjct: 1054 MAPASESSASG---------APLDENDLE----EDVDSEPAEIE--GEAAEDGD------ 1092

Query: 332  IPPPSAFLKAWVYWPGEDTEEEEDEEEDEDSDSGSDEE-------EGEAEASSSTPATGV 384
                          PG+   E +D++   DS S +D E       EGEAE          
Sbjct: 1093 --------------PGDTGAELDDDQHWSDSPSDADRELRLPCPAEGEAEL--------- 1129

Query: 385  FLKSWVYQPGEDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRP--GEDTEE 442
                       +    EDE+    S + +    + A++P  S    A ++ P     TE 
Sbjct: 1130 -----------ELRVSEDEEKLPASPKHQERGPSQATSPIRSPQESALLFIPVHSPSTEG 1178

Query: 443  EEDEDVDSEDKEDDSEAALGEAESDPHPSHPDQRAHFRGWGYRPGKETEEEEAAEDWGEA 502
             +   V +  +E   E  L      P P  P ++               + +A      +
Sbjct: 1179 PQLPPVPAATQEKSPEERL-----FPEPLLPKEKP--------KADAPSDLKAVHSPIRS 1225

Query: 503  EPCPF---RVAIYVPGEKPPPPWA---PPRLPLRLQRRLKRPETPTHDPDP-ETPLKARK 555
            +P      R  +     +P PP A   PP  PL +  +  +P T    P P ++P++ + 
Sbjct: 1226 QPVTLPEARTPVSPGSPQPQPPVAASTPPPSPLPICSQ-PQPSTEATVPSPTQSPIRFQP 1284

Query: 556  VRFSEKVTVHFLAVWAGPAQAARQGPWEQLARD----RSRFARRITQAQEEL--SPCLTP 609
                    +  L V +      R G    LA D    RS           E+  S  LTP
Sbjct: 1285 APAKTSTPLAPLPVQSQSDTKDRLG--SPLAVDEALRRSDLVEEFWMKSAEIRRSLGLTP 1342

Query: 610  AARARAWARLRNPPLAPIPALTQ-TLPSSSVPSSP 643
              R++        P  P PA    +L S SV  SP
Sbjct: 1343 VDRSKG-----PEPSFPTPAFRPVSLKSYSVEKSP 1372



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 40/183 (21%), Positives = 59/183 (32%), Gaps = 36/183 (19%)

Query: 510  AIYVPGEKPPPPWAPPRLPLRLQRRLKRPETPTHDPDPETPLKARKVRFSEKVTVHFLAV 569
            A+  P   PPPP  P   P  L+R+L+  E       P  P                 A 
Sbjct: 1451 AMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLP-----------------AT 1493

Query: 570  WAGPAQAARQGPWEQLARDRSRFARRI-------------TQAQEELSPCLTPAARARAW 616
            W  P +   Q P E++ +        I             T+         TP +     
Sbjct: 1494 WMRPPREPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWPRP 1553

Query: 617  ARLRNPPLAP----IPALTQTL--PSSSVPSSPVQTTPLSQAVATPSRSSAAAAAALDLS 670
             + R+PPLA     +PAL  TL      +P    +   L++        S  + A  D  
Sbjct: 1554 EKPRHPPLAKENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAM 1613

Query: 671  GRR 673
             R+
Sbjct: 1614 ARQ 1616


>gi|83700233 eukaryotic translation initiation factor 3, subunit C
           [Homo sapiens]
          Length = 913

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 22/137 (16%)

Query: 348 EDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPG------------- 394
           E + +E+ E+ +EDS+  SDE+E E   S++T     FLK     P              
Sbjct: 164 EQSADEDAEKNEEDSEGSSDEDEDEDGVSAAT-----FLKKKSEAPSGESRKFLKKMDDE 218

Query: 395 ----EDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDS 450
               ED+E++ED D+ + S++ + E E    T  AS FLK       +    E+  +  +
Sbjct: 219 DEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKA 278

Query: 451 EDKEDDSEAALGEAESD 467
           + K D     L E E D
Sbjct: 279 KKKHDRKSKRLDEEEED 295



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 13/134 (9%)

Query: 288 PQSSAP--AQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYW 345
           P+ SA   A++ +  S      DE+E  V A    +K  EA        PS   + ++  
Sbjct: 163 PEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEA--------PSGESRKFLKK 214

Query: 346 PGEDTEEEEDEEEDEDSDSG--SDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDE 403
             ++ E+ ED E+DED D+G  S + + E E    T     FLK       ED +  E +
Sbjct: 215 MDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKK-APTTDEDKKAAEKK 273

Query: 404 DSDTGSAEDEREAE 417
             D    + +R+++
Sbjct: 274 REDKAKKKHDRKSK 287


>gi|4503525 eukaryotic translation initiation factor 3, subunit C
           [Homo sapiens]
          Length = 913

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 22/137 (16%)

Query: 348 EDTEEEEDEEEDEDSDSGSDEEEGEAEASSSTPATGVFLKSWVYQPG------------- 394
           E + +E+ E+ +EDS+  SDE+E E   S++T     FLK     P              
Sbjct: 164 EQSADEDAEKNEEDSEGSSDEDEDEDGVSAAT-----FLKKKSEAPSGESRKFLKKMDDE 218

Query: 395 ----EDTEEEEDEDSDTGSAEDEREAETSASTPPASAFLKAWVYRPGEDTEEEEDEDVDS 450
               ED+E++ED D+ + S++ + E E    T  AS FLK       +    E+  +  +
Sbjct: 219 DEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKA 278

Query: 451 EDKEDDSEAALGEAESD 467
           + K D     L E E D
Sbjct: 279 KKKHDRKSKRLDEEEED 295



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 13/134 (9%)

Query: 288 PQSSAP--AQRPQLKSWWCQPSDEEEGEVKALGAAEKDGEAECPPCIPPPSAFLKAWVYW 345
           P+ SA   A++ +  S      DE+E  V A    +K  EA        PS   + ++  
Sbjct: 163 PEQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEA--------PSGESRKFLKK 214

Query: 346 PGEDTEEEEDEEEDEDSDSG--SDEEEGEAEASSSTPATGVFLKSWVYQPGEDTEEEEDE 403
             ++ E+ ED E+DED D+G  S + + E E    T     FLK       ED +  E +
Sbjct: 215 MDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKK-APTTDEDKKAAEKK 273

Query: 404 DSDTGSAEDEREAE 417
             D    + +R+++
Sbjct: 274 REDKAKKKHDRKSK 287


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.126    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,593,636
Number of Sequences: 37866
Number of extensions: 2211685
Number of successful extensions: 32713
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 425
Number of HSP's successfully gapped in prelim test: 911
Number of HSP's that attempted gapping in prelim test: 13174
Number of HSP's gapped (non-prelim): 9071
length of query: 674
length of database: 18,247,518
effective HSP length: 109
effective length of query: 565
effective length of database: 14,120,124
effective search space: 7977870060
effective search space used: 7977870060
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.