Search of human proteins with 157426875

Search of human proteins with 157426875

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157426875 F-box and leucine-rich repeat protein 18 [Homo
sapiens]
         (718 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157426875 F-box and leucine-rich repeat protein 18 [Homo sapi...  1425   0.0  
gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]     48   3e-05
gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]     48   3e-05
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]     39   0.017
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]    38   0.029
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    34   0.54 
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    34   0.54 
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ...    33   0.92 
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ...    33   0.92 
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    33   0.92 
gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]        33   1.2  
gi|30520327 F-box protein 27 [Homo sapiens]                            33   1.2  
gi|148746189 multiple PDZ domain protein [Homo sapiens]                32   2.1  
gi|119508433 melanocortin 4 receptor [Homo sapiens]                    32   2.7  
gi|169164474 PREDICTED: hypothetical protein [Homo sapiens]            32   2.7  
gi|239747958 PREDICTED: hypothetical protein isoform 4 [Homo sap...    32   2.7  
gi|239741853 PREDICTED: hypothetical protein isoform 2 [Homo sap...    32   2.7  
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    32   2.7  
gi|223029410 talin 1 [Homo sapiens]                                    31   3.5  
gi|94536788 THAP domain containing 9 [Homo sapiens]                    31   4.6  
gi|63003903 leucine rich repeat containing 10 [Homo sapiens]           31   4.6  
gi|4505763 phosphoglycerate kinase 1 [Homo sapiens]                    31   4.6  
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof...    31   4.6  
gi|120953243 leucine-rich repeats and IQ motif containing 1 isof...    31   4.6  
gi|17975763 myelin transcription factor 1 [Homo sapiens]               30   6.0  
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi...    30   6.0  
gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo ...    30   7.8  
gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo ...    30   7.8  
gi|190194355 p90 autoantigen [Homo sapiens]                            30   7.8  
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    30   7.8  

>gi|157426875 F-box and leucine-rich repeat protein 18 [Homo
           sapiens]
          Length = 718

 Score = 1425 bits (3690), Expect = 0.0
 Identities = 718/718 (100%), Positives = 718/718 (100%)

Query: 1   MASSGEDISNDDDDMHPAAAGMADGVHLLGFSDEILLHILSHVPSTDLILNVRRTCRKLA 60
           MASSGEDISNDDDDMHPAAAGMADGVHLLGFSDEILLHILSHVPSTDLILNVRRTCRKLA
Sbjct: 1   MASSGEDISNDDDDMHPAAAGMADGVHLLGFSDEILLHILSHVPSTDLILNVRRTCRKLA 60

Query: 61  ALCLDKSLIHTVLLQKDYQASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARCRS 120
           ALCLDKSLIHTVLLQKDYQASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARCRS
Sbjct: 61  ALCLDKSLIHTVLLQKDYQASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARCRS 120

Query: 121 LVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTL 180
           LVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTL
Sbjct: 121 LVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQTL 180

Query: 181 FTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSGQLMVGQSNVPHYQNLRVFYARLAPG 240
           FTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSGQLMVGQSNVPHYQNLRVFYARLAPG
Sbjct: 181 FTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSGQLMVGQSNVPHYQNLRVFYARLAPG 240

Query: 241 YINQEVVRLYLAVLSDRTPQNLHAFLISVPGSFAESGATKNLLDSMARNVVLDALQLPKS 300
           YINQEVVRLYLAVLSDRTPQNLHAFLISVPGSFAESGATKNLLDSMARNVVLDALQLPKS
Sbjct: 241 YINQEVVRLYLAVLSDRTPQNLHAFLISVPGSFAESGATKNLLDSMARNVVLDALQLPKS 300

Query: 301 WLNGSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPD 360
           WLNGSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPD
Sbjct: 301 WLNGSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPD 360

Query: 361 SLLRKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRHLCQLLARLRHLRSLSL 420
           SLLRKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRHLCQLLARLRHLRSLSL
Sbjct: 361 SLLRKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRHLCQLLARLRHLRSLSL 420

Query: 421 PVCSVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQSCPSPFSGQACPQPSSVFWSLLK 480
           PVCSVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQSCPSPFSGQACPQPSSVFWSLLK
Sbjct: 421 PVCSVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQSCPSPFSGQACPQPSSVFWSLLK 480

Query: 481 NLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQ 540
           NLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQ
Sbjct: 481 NLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQ 540

Query: 541 LPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRLRDLRLEQPYF 600
           LPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRLRDLRLEQPYF
Sbjct: 541 LPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRLRDLRLEQPYF 600

Query: 601 SANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFTGESLATCKSL 660
           SANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFTGESLATCKSL
Sbjct: 601 SANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFTGESLATCKSL 660

Query: 661 QQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPLVHLDEITLFKSRVAEEPPNLWW 718
           QQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPLVHLDEITLFKSRVAEEPPNLWW
Sbjct: 661 QQSLLRSFQAERPALNVVIFPLLHEGLTDVIRDVPLVHLDEITLFKSRVAEEPPNLWW 718


>gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 57/208 (27%), Positives = 87/208 (41%), Gaps = 48/208 (23%)

Query: 477 SLLKNLPFLEHLELIGSNFSSAMPRNEPAI------RNSLPPCSRAQSVGDSEVAAIGQL 530
           S LK+ P LEH +  G+  +   P+    +         L  CS+   + D+ +A + Q 
Sbjct: 44  SSLKSRPELEH-QASGTKDACPEPQGPSLLTLRALQELDLTACSK---LTDASLAKVLQF 99

Query: 531 AFLRHLTLAQLPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRL 590
             LR L+L+ LP  LT +GLV +   C  L  L+L+                   HC RL
Sbjct: 100 LQLRQLSLSLLPE-LTDNGLVAVARGCPSLEHLALS-------------------HCSRL 139

Query: 591 RDLRLEQPYFSANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFT 650
            D             + QA S  P LQ L L S S  ++   + A    C Q+ +     
Sbjct: 140 SD-----------KGWAQAASSWPRLQHLNLSSCSQLIE-QTLDAIGQACRQLRVL---- 183

Query: 651 GESLATCKSLQQSLLRSFQAERPALNVV 678
              +ATC  +  + +R FQA+ P ++ V
Sbjct: 184 --DVATCPGINMAAVRRFQAQLPQVSCV 209


>gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 57/208 (27%), Positives = 87/208 (41%), Gaps = 48/208 (23%)

Query: 477 SLLKNLPFLEHLELIGSNFSSAMPRNEPAI------RNSLPPCSRAQSVGDSEVAAIGQL 530
           S LK+ P LEH +  G+  +   P+    +         L  CS+   + D+ +A + Q 
Sbjct: 44  SSLKSRPELEH-QASGTKDACPEPQGPSLLTLRALQELDLTACSK---LTDASLAKVLQF 99

Query: 531 AFLRHLTLAQLPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRL 590
             LR L+L+ LP  LT +GLV +   C  L  L+L+                   HC RL
Sbjct: 100 LQLRQLSLSLLPE-LTDNGLVAVARGCPSLEHLALS-------------------HCSRL 139

Query: 591 RDLRLEQPYFSANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLFT 650
            D             + QA S  P LQ L L S S  ++   + A    C Q+ +     
Sbjct: 140 SD-----------KGWAQAASSWPRLQHLNLSSCSQLIE-QTLDAIGQACRQLRVL---- 183

Query: 651 GESLATCKSLQQSLLRSFQAERPALNVV 678
              +ATC  +  + +R FQA+ P ++ V
Sbjct: 184 --DVATCPGINMAAVRRFQAQLPQVSCV 209


>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
          Length = 423

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 71/337 (21%), Positives = 121/337 (35%), Gaps = 65/337 (19%)

Query: 345 LASLNLSGCVHCLSPDSLLRKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRH 404
           L  L+L GC+               +  S L+T   +C N+ HLNL+     +       
Sbjct: 80  LRKLSLRGCI--------------GVGDSSLKTFAQNCRNIEHLNLNGCTKITDS----- 120

Query: 405 LCQLLARL-RHLRSLSLPVC-SVADSAPRADRAPAQPAMHAVPRGFGKKVRVGVQSCPSP 462
            C  L+R    L+ L L  C S+ +S+ +      +   +       +  + G+++    
Sbjct: 121 TCYSLSRFCSKLKHLDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRG 180

Query: 463 FSG------QACPQPSSVFWSLLKNLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRA 516
             G      + C Q        LK++    H EL+  N  S     +  +      C R 
Sbjct: 181 CRGLKALLLRGCTQLED---EALKHIQNYCH-ELVSLNLQSCSRITDEGVVQICRGCHRL 236

Query: 517 QSVGDSEVAAIGQLAFLRHLTLAQLPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVY 576
           Q++  S                    S LT + L  +GL C +L+ L  A    +    +
Sbjct: 237 QALCLSGC------------------SNLTDASLTALGLNCPRLQILEAARCSHLTDAGF 278

Query: 577 MPALSDMLKHCKRLRDLRLEQPYFSANAQFFQALSQCPSLQRLCLVSRSGTLQPDAVLAF 636
               + + ++C  L  + LE+     ++   Q    CP LQ L L S    +  D +L  
Sbjct: 279 ----TLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSL-SHCELITDDGILHL 333

Query: 637 --------MARCLQVVMCHLFTG---ESLATCKSLQQ 662
                     R L++  C L T    E L  C+ L++
Sbjct: 334 SNSTCGHERLRVLELDNCLLITDVALEHLENCRGLER 370



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 22/67 (32%), Positives = 38/67 (56%), Gaps = 5/67 (7%)

Query: 85  VRQLVKEIGREIQQLSMAGCYWLPGSTVEHVAR-CRSLVKVNLSGC----HLTSLRLSKM 139
           V  + K  G  +++LS+ GC  +  S+++  A+ CR++  +NL+GC      T   LS+ 
Sbjct: 69  VENISKRCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRF 128

Query: 140 LSALQHL 146
            S L+HL
Sbjct: 129 CSKLKHL 135



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 26/95 (27%), Positives = 44/95 (46%), Gaps = 13/95 (13%)

Query: 56  CRKLAALCLDKSLIHTVLLQKDYQASEDKVRQLVKEI-GRE-IQQLSMAGCYWLPGSTVE 113
           C KL AL    SL H  L+      ++D +  L     G E ++ L +  C  +    +E
Sbjct: 311 CPKLQAL----SLSHCELI------TDDGILHLSNSTCGHERLRVLELDNCLLITDVALE 360

Query: 114 HVARCRSLVKVNLSGC-HLTSLRLSKMLSALQHLR 147
           H+  CR L ++ L  C  +T   + +M + L H++
Sbjct: 361 HLENCRGLERLELYDCQQVTRAGIKRMRAQLPHVK 395


>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
          Length = 436

 Score = 38.1 bits (87), Expect = 0.029
 Identities = 39/141 (27%), Positives = 60/141 (42%), Gaps = 11/141 (7%)

Query: 34  EILLHILSHVPSTDLILNVRRTCRKLAALCLDKSLIHTVLL---QKDYQASEDKVRQLVK 90
           E+LL I S +    L     +  R    L LD S    + L   Q+D +     V  + K
Sbjct: 31  ELLLRIFSFLDVVTLC-RCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRV--VENISK 87

Query: 91  EIGREIQQLSMAGCYWLPGSTVEHVAR-CRSLVKVNLSGC----HLTSLRLSKMLSALQH 145
             G  +++LS+ GC  +  + +   A+ CR++  +NL+GC      T   LSK  S L+H
Sbjct: 88  RCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRH 147

Query: 146 LRSLAIDVSPGFDASQLSSEC 166
           L   +           LS  C
Sbjct: 148 LDLASCTSITNMSLKALSEGC 168



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 55/296 (18%), Positives = 105/296 (35%), Gaps = 75/296 (25%)

Query: 345 LASLNLSGCVHCLSPDSLLRKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRH 404
           L  L+L GC+               +  + L T   +C N+  LNL+     +++     
Sbjct: 93  LRKLSLRGCL--------------GVGDNALRTFAQNCRNIEVLNLNGCTK-TTDATCTS 137

Query: 405 LCQLLARLRHLRSLS------LPVCSVADSAPRADRAP-------AQPAMHAVPRGFGKK 451
           L +  ++LRHL   S      + + ++++  P  ++          +  + A+ RG G  
Sbjct: 138 LSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGL 197

Query: 452 VRVGVQSCPS------PFSGQACPQPSSVFWSLLKNLPFLEHLELIGSNFSSAMPRNEPA 505
             + ++ C         + G  CP                   EL+  N  + +   +  
Sbjct: 198 KALFLKGCTQLEDEALKYIGAHCP-------------------ELVTLNLQTCLQITDEG 238

Query: 506 IRNSLPPCSRAQSVGDSEVAAIGQLAFLRHLTLAQLPSVLTGSGLVNIGLQCQQLRSLSL 565
           +      C + QS+  S  + I                  T + L  +G  C +LR L +
Sbjct: 239 LITICRGCHKLQSLCASGCSNI------------------TDAILNALGQNCPRLRILEV 280

Query: 566 ANLGMMGKVVYMPALSDMLKHCKRLRDLRLEQPYFSANAQFFQALSQCPSLQRLCL 621
           A    +  V +    + + ++C  L  + LE+     ++   Q    CP LQ L L
Sbjct: 281 ARCSQLTDVGF----TTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSL 332


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 53/202 (26%), Positives = 77/202 (38%), Gaps = 50/202 (24%)

Query: 485  LEHLELIGSNFSSAMP---RNEPAIRNSL---PPCSRAQSVGDSEVAAIGQLAFLRHLTL 538
            LE L ++ S F   M      +P I  +L   PP   AQ++    +A   +L   + L  
Sbjct: 4272 LEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQML-- 4329

Query: 539  AQLPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRLRDL----- 593
              L S++  +  V             +A+LG+  + V   ALSD   H   L DL     
Sbjct: 4330 --LKSLIKDADRV-------------MADLGLNERQVIQKALSDAQSHVNCLSDLVGQRR 4374

Query: 594  RLEQPYFSANAQF----FQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLF 649
            +      S   QF    FQA SQ    +R  +      L PD V                
Sbjct: 4375 KYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDV---------------- 4418

Query: 650  TGESLATCKSLQQSLLRSFQAE 671
              + + TCKS Q S L+++Q E
Sbjct: 4419 -SKQVKTCKSAQAS-LKTYQNE 4438


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 53/202 (26%), Positives = 77/202 (38%), Gaps = 50/202 (24%)

Query: 485  LEHLELIGSNFSSAMP---RNEPAIRNSL---PPCSRAQSVGDSEVAAIGQLAFLRHLTL 538
            LE L ++ S F   M      +P I  +L   PP   AQ++    +A   +L   + L  
Sbjct: 4343 LEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQML-- 4400

Query: 539  AQLPSVLTGSGLVNIGLQCQQLRSLSLANLGMMGKVVYMPALSDMLKHCKRLRDL----- 593
              L S++  +  V             +A+LG+  + V   ALSD   H   L DL     
Sbjct: 4401 --LKSLIKDADRV-------------MADLGLNERQVIQKALSDAQSHVNCLSDLVGQRR 4445

Query: 594  RLEQPYFSANAQF----FQALSQCPSLQRLCLVSRSGTLQPDAVLAFMARCLQVVMCHLF 649
            +      S   QF    FQA SQ    +R  +      L PD V                
Sbjct: 4446 KYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDV---------------- 4489

Query: 650  TGESLATCKSLQQSLLRSFQAE 671
              + + TCKS Q S L+++Q E
Sbjct: 4490 -SKQVKTCKSAQAS-LKTYQNE 4509


>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 33.1 bits (74), Expect = 0.92
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 15/83 (18%)

Query: 320 SFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPDSLLRKAEDDIDSSILETLV 379
           + + C   G   ++Q ++G   +R +  LNLS CV  LS  S+++ +E            
Sbjct: 457 NLANCVRIGDMGLKQFLDGPASMR-IRELNLSNCVR-LSDASVMKLSE------------ 502

Query: 380 ASCCNLRHLNLSAAHHHSSEGLG 402
             C NL +L+L    H +++G+G
Sbjct: 503 -RCPNLNYLSLRNCEHLTAQGIG 524


>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
           [Homo sapiens]
          Length = 735

 Score = 33.1 bits (74), Expect = 0.92
 Identities = 23/83 (27%), Positives = 41/83 (49%), Gaps = 15/83 (18%)

Query: 320 SFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPDSLLRKAEDDIDSSILETLV 379
           + + C   G   ++Q ++G   +R +  LNLS CV  LS  S+++ +E            
Sbjct: 457 NLANCVRIGDMGLKQFLDGPASMR-IRELNLSNCVR-LSDASVMKLSE------------ 502

Query: 380 ASCCNLRHLNLSAAHHHSSEGLG 402
             C NL +L+L    H +++G+G
Sbjct: 503 -RCPNLNYLSLRNCEHLTAQGIG 524


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 33.1 bits (74), Expect = 0.92
 Identities = 29/86 (33%), Positives = 43/86 (50%), Gaps = 8/86 (9%)

Query: 344 SLASLNLSGCVHCLSPDSLLRKAE--DDIDSSILETLVASCCNLRHLNLSAAHHHSSEGL 401
           S+A++ LS      S + L RK E  D+I S  LE L   C NL +LNLS      ++  
Sbjct: 48  SMANVELSSLARLPSLNKL-RKLELSDNIISGGLEVLAEKCPNLTYLNLS-----GNKIK 101

Query: 402 GRHLCQLLARLRHLRSLSLPVCSVAD 427
                + L  L++L+SL L  C + +
Sbjct: 102 DLSTVEALQNLKNLKSLDLFNCEITN 127


>gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]
          Length = 1378

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 58/246 (23%), Positives = 89/246 (36%), Gaps = 17/246 (6%)

Query: 176  LKQTLFTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSGQLMVGQSNVPHYQNLRVFYA 235
            L Q   TP    +   T+L +L L        R G     +L+     +P    L +   
Sbjct: 1054 LDQAQLTPLLRALKLHTALRELRLA-----GNRLGDKCVAELVAALGTMPSLALLDLSSN 1108

Query: 236  RLAPGYINQEVVRLYLAVLSDRTPQNLHAFLISVPGSFAESGATKNLLDSMARNVVLDAL 295
             L P  + Q    L + +    T Q+L    +S+  +    G  ++L   +    +L  L
Sbjct: 1109 HLGPEGLRQ----LAMGLPGQATLQSLEELDLSM--NPLGDGCGQSLASLLHACPLLSTL 1162

Query: 296  QLPKSWLNGSSLLQHMK-FNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCV 354
            +L       S  L H     + F  +    TLS   L    +      R+L SL     +
Sbjct: 1163 RLQACGFGPSFFLSHQTALGSAFQDAEHLKTLS---LSYNALGAPALARTLQSLPAGTLL 1219

Query: 355  HCLSPDSLLRKAEDDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLGRHLCQLLARLRH 414
            H         K + D+   +   L    C L HL LSA  +H  +   R LC+ L+    
Sbjct: 1220 HLELSSVAAGKGDSDLMEPVFRYLAKEGCALAHLTLSA--NHLGDKAVRDLCRCLSLCPS 1277

Query: 415  LRSLSL 420
            L SL L
Sbjct: 1278 LISLDL 1283


>gi|30520327 F-box protein 27 [Homo sapiens]
          Length = 283

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 18/48 (37%), Positives = 29/48 (60%), Gaps = 1/48 (2%)

Query: 34 EILLHILSHVPSTDLILNVRRTCRKLAALCLDKSLIHTVLLQKDYQAS 81
          E+LL +LSHVP   L+   R+ CR   AL +D   +  ++L +D+ A+
Sbjct: 32 ELLLVVLSHVPPRTLLGRCRQVCRGWRAL-VDGQALWLLILARDHGAT 78


>gi|148746189 multiple PDZ domain protein [Homo sapiens]
          Length = 2041

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 8/68 (11%)

Query: 24  DGVHLLGFSDEILLHILSHVPSTDLILNVRRTCRKLAALC--------LDKSLIHTVLLQ 75
           DG +L GF+++  + +L H   T L+  +RR  ++ A L          D S ++  +++
Sbjct: 432 DGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRGMKQEAELMSREDVTKDADLSPVNASIIK 491

Query: 76  KDYQASED 83
           ++Y+  ED
Sbjct: 492 ENYEKDED 499


>gi|119508433 melanocortin 4 receptor [Homo sapiens]
          Length = 332

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 8/133 (6%)

Query: 254 LSDRTPQNLHAFLISVPGS-FAESGATKNLLDSMARNVVLDALQLPKSWLNGSSLLQHMK 312
           L +R+   LH+      G  +++ G  + L  S    V L  + L ++ L   ++ ++  
Sbjct: 15  LWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKN 74

Query: 313 FNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASLNLSGCVHCLSPDSLLRKAEDDIDS 372
            ++P YF    C+L+   ++  V NG + +  +  LN +         S     ++ IDS
Sbjct: 75  LHSPMYFFI--CSLAVADMLVSVSNGSETI-VITLLNSTDT----DAQSFTVNIDNVIDS 127

Query: 373 SILETLVASCCNL 385
            I  +L+AS C+L
Sbjct: 128 VICSSLLASICSL 140


>gi|169164474 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 259

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 3/40 (7%)

Query: 79  QASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARC 118
           Q +E + R LV+E+GR     + AGC  LPG+T     RC
Sbjct: 126 QTAERQARPLVRELGRGS---AAAGCPSLPGATTPRPRRC 162


>gi|239747958 PREDICTED: hypothetical protein isoform 4 [Homo
           sapiens]
          Length = 259

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 3/40 (7%)

Query: 79  QASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARC 118
           Q +E + R LV+E+GR     + AGC  LPG+T     RC
Sbjct: 126 QTAERQARPLVRELGRGS---AAAGCPSLPGATTPRPRRC 162


>gi|239741853 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 259

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 3/40 (7%)

Query: 79  QASEDKVRQLVKEIGREIQQLSMAGCYWLPGSTVEHVARC 118
           Q +E + R LV+E+GR     + AGC  LPG+T     RC
Sbjct: 126 QTAERQARPLVRELGRGS---AAAGCPSLPGATTPRPRRC 162


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 28/85 (32%), Positives = 42/85 (49%), Gaps = 8/85 (9%)

Query: 345 LASLNLSGCVHCLSPDSLLRKAE--DDIDSSILETLVASCCNLRHLNLSAAHHHSSEGLG 402
           +A++ LS      S + L RK E  D+I S  LE L   C NL +LNLS      ++   
Sbjct: 1   MANVELSSLARLPSLNKL-RKLELSDNIISGGLEVLAEKCPNLTYLNLS-----GNKIKD 54

Query: 403 RHLCQLLARLRHLRSLSLPVCSVAD 427
               + L  L++L+SL L  C + +
Sbjct: 55  LSTVEALQNLKNLKSLDLFNCEITN 79


>gi|223029410 talin 1 [Homo sapiens]
          Length = 2541

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 42/180 (23%), Positives = 71/180 (39%), Gaps = 29/180 (16%)

Query: 119  RSLVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSPGFDASQLSSECKATLSRVRELKQ 178
            R+ V  NL G  ++S   SK+L A    ++L+ D +     SQL++  +A    + +L  
Sbjct: 1298 RAQVVSNLKGISMSS---SKLLLAA---KALSTDPAAPNLKSQLAAAARAVTDSINQLIT 1351

Query: 179  TLFTPSYGVVPCCTSLEKL----------------LLYFEILDRTREGAILSGQLMVGQS 222
                 + G   C  +L +L                + YF  LD   E + + G+ M G S
Sbjct: 1352 MCTQQAPGQKECDNALRELETVRELLENPVQPINDMSYFGCLDSVMENSKVLGEAMTGIS 1411

Query: 223  ------NVPHYQNLRVFYARLAPGYINQEVVRLYLAVLSDRTPQNLHAFLISVPGSFAES 276
                  N+P + +     ++   G+        YL  +SD   Q     L+  P  FA +
Sbjct: 1412 QNAKNGNLPEFGDAISTASKALCGFTEAAAQAAYLVGVSDPNSQAGQQGLVE-PTQFARA 1470


>gi|94536788 THAP domain containing 9 [Homo sapiens]
          Length = 903

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 46/195 (23%), Positives = 86/195 (44%), Gaps = 35/195 (17%)

Query: 230 LRVFYARLAPGYINQEVVRLYLAVLSDRTPQNLHAFLISVPGSFAESGATKNLLD-SMAR 288
           L  F+   A GY+  +++RL +  LSD          I +      S AT + +  + A 
Sbjct: 337 LGYFFVNRASGYLQAQLLRLTIGKLSD----------IGITVLAVTSDATAHSVQMAKAL 386

Query: 289 NVVLDALQLPKSWLNGSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQVINGGKDLRSLASL 348
            + +D   +  ++ + SS  Q +      YF F  C     HL++ + N  ++ +S+  +
Sbjct: 387 GIHIDGDDMKCTFQHPSSSSQQIA-----YF-FDSC-----HLLRLIRNAFQNFQSIQFI 435

Query: 349 NLSGCVHCLSPDSLLRKAEDDIDSSILETLVASCCNLRH--LNLSAAHHHSSEGLGRHLC 406
           N  G  H      L+   E ++  S +E + ++  NL++  L +++A    SE +     
Sbjct: 436 N--GIAHWQHLVELVALEEQEL--SNMERIPSTLANLKNHVLKVNSATQLFSESVA---- 487

Query: 407 QLLARLRHLRSLSLP 421
              + L +L SL LP
Sbjct: 488 ---SALEYLLSLDLP 499


>gi|63003903 leucine rich repeat containing 10 [Homo sapiens]
          Length = 277

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 23/63 (36%), Positives = 34/63 (53%), Gaps = 6/63 (9%)

Query: 94  REIQQLSMAGCYWLPGSTVE----HVARCRSLVKVNLSGCHLTSLRLSKMLSALQHLRSL 149
           R+++++ +     L GS +     HV   R LVK+ LS  HL S  L   L  LQ+L+ L
Sbjct: 23  RDLREMPLDKMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNS--LPPELGQLQNLQIL 80

Query: 150 AID 152
           A+D
Sbjct: 81  ALD 83


>gi|4505763 phosphoglycerate kinase 1 [Homo sapiens]
          Length = 417

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 1/79 (1%)

Query: 427 DSAPRADRAPAQPAMHAVPRGFGKKVRVGVQSCPSPFSGQACPQPSSVFWSLLKNLPFLE 486
           D  P  D+   +P    +    GK V + ++ C  P   +AC  P++    LL+NL F  
Sbjct: 68  DGVPMPDKYSLEPVAVELKSLLGKDV-LFLKDCVGPEVEKACANPAAGSVILLENLRFHV 126

Query: 487 HLELIGSNFSSAMPRNEPA 505
             E  G + S    + EPA
Sbjct: 127 EEEGKGKDASGNKVKAEPA 145


>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform
           1 [Homo sapiens]
          Length = 1722

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 9/147 (6%)

Query: 96  IQQLSMAGCYWLPGSTVEHVARCRSLVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSP 155
           +QQ++      LPG  +  +A C +L  ++L  C LTSL        L+++ +    +  
Sbjct: 795 LQQVTTVTFQDLPGCVLSTLAECTNLQFLSLRRCGLTSLHSLSNCKKLKYIDAQENHIE- 853

Query: 156 GFDASQLSSECKATLSRVRELKQTLFTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSG 215
             +   L + C   L++         T  +G +  CT+++ L L +  + R      L  
Sbjct: 854 AIECENLENLCVVLLNK------NQLTSLHG-LDGCTNIQCLELSYNKITRIGYSFFLEE 906

Query: 216 QLMVGQSNVPHYQNLRVFYARLAPGYI 242
           +L V  +   H+      Y  LA  +I
Sbjct: 907 KL-VDNAGFCHHLGTSTSYLSLAQVWI 932


>gi|120953243 leucine-rich repeats and IQ motif containing 1 isoform
           2 [Homo sapiens]
          Length = 1336

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 33/147 (22%), Positives = 61/147 (41%), Gaps = 9/147 (6%)

Query: 96  IQQLSMAGCYWLPGSTVEHVARCRSLVKVNLSGCHLTSLRLSKMLSALQHLRSLAIDVSP 155
           +QQ++      LPG  +  +A C +L  ++L  C LTSL        L+++ +    +  
Sbjct: 795 LQQVTTVTFQDLPGCVLSTLAECTNLQFLSLRRCGLTSLHSLSNCKKLKYIDAQENHIE- 853

Query: 156 GFDASQLSSECKATLSRVRELKQTLFTPSYGVVPCCTSLEKLLLYFEILDRTREGAILSG 215
             +   L + C   L++         T  +G +  CT+++ L L +  + R      L  
Sbjct: 854 AIECENLENLCVVLLNK------NQLTSLHG-LDGCTNIQCLELSYNKITRIGYSFFLEE 906

Query: 216 QLMVGQSNVPHYQNLRVFYARLAPGYI 242
           +L V  +   H+      Y  LA  +I
Sbjct: 907 KL-VDNAGFCHHLGTSTSYLSLAQVWI 932


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 35/153 (22%), Positives = 59/153 (38%), Gaps = 24/153 (15%)

Query: 283 LDSMARNVVLDALQLPKSWLNGSSLLQHMKFNNPFYFSFSRCTLSGGHLIQQVINGGKDL 342
           L  +++++  + L  P    +GS    H+  N   + S S C L+   L   +     DL
Sbjct: 786 LKFLSKDIKKELLTCPTPGCDGSG---HITGNYASHRSLSGCPLADKSLRNLMAAHSADL 842

Query: 343 RS---------------LASLNLSGCVHCLSPDSLLRKAEDDI-DSSILETLVASCCNLR 386
           +                 +  +LSGC         +   +DD  D  +++  V  C  L 
Sbjct: 843 KCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGLG 902

Query: 387 HLNLSAAHHHSSEGLGRHLCQLLARLRHLRSLS 419
           H++   A H S+ G     C L AR +   SL+
Sbjct: 903 HISGKYASHRSASG-----CPLAARRQKEGSLN 930


>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
           sapiens]
          Length = 300

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 96  IQQLSMAGCYWLPGSTVEHVA-RCRSLVKVNLSGCHLTS----LRLSKMLSALQHLRSLA 150
           +Q+LS+A C W+ G  +  +A RC +L +++L+ C        + L++   A     SLA
Sbjct: 142 LQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLA 201

Query: 151 IDVSPGFDASQ-LSSEC 166
           ++ + G  A Q L+  C
Sbjct: 202 VNANVGDAAVQELARNC 218


>gi|16306595 S-phase kinase-associated protein 2 isoform 1 [Homo
           sapiens]
          Length = 424

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 26/96 (27%)

Query: 308 LQHMKFNNP------FYFSFSRCT------LSGGHLIQQVINGGKDLRSLASLNLSGCVH 355
           +QHM  +N        +   S+C+      L G  L   ++N      +L  LNLSGC  
Sbjct: 183 VQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC-- 240

Query: 356 CLSPDSLLRKAEDDIDSSILETLVASCCNLRHLNLS 391
                              L+TL++SC  L  LNLS
Sbjct: 241 ------------SGFSEFALQTLLSSCSRLDELNLS 264


>gi|14249170 S-phase kinase-associated protein 2 isoform 2 [Homo
           sapiens]
          Length = 410

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 26/96 (27%)

Query: 308 LQHMKFNNP------FYFSFSRCT------LSGGHLIQQVINGGKDLRSLASLNLSGCVH 355
           +QHM  +N        +   S+C+      L G  L   ++N      +L  LNLSGC  
Sbjct: 183 VQHMDLSNSVIEVSTLHGILSQCSKLQNLSLEGLRLSDPIVNTLAKNSNLVRLNLSGC-- 240

Query: 356 CLSPDSLLRKAEDDIDSSILETLVASCCNLRHLNLS 391
                              L+TL++SC  L  LNLS
Sbjct: 241 ------------SGFSEFALQTLLSSCSRLDELNLS 264


>gi|190194355 p90 autoantigen [Homo sapiens]
          Length = 905

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 29/87 (33%), Positives = 38/87 (43%), Gaps = 12/87 (13%)

Query: 349 NLSGCVHCLSPDSLLRKAEDDIDSSILETLVASC--CNLRHLNLSAAHHHSSEG---LGR 403
           + S C+H +    LL   + D  S +LE L+A C    LRH+        S  G   LG 
Sbjct: 276 HFSSCLHQVL--GLLNGKDPDSSSKVLELLLAFCSVTQLRHMLTQMMFEQSPPGSATLGS 333

Query: 404 HLCQLLARLRHLRSLSLPV-----CSV 425
           H   L   +  LR LS P+     CSV
Sbjct: 334 HTKCLEPTVALLRWLSQPLDGSENCSV 360


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 32/129 (24%), Positives = 52/129 (40%), Gaps = 4/129 (3%)

Query: 415 LRSLSLPVCSVADSAPRADRAPAQPAMHAVPRGF--GKKVRVGVQSCPSPFSGQACPQPS 472
           L    LP    AD       A    A+ A P+    G    +G+Q  P+  + QA   P 
Sbjct: 126 LGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQ 185

Query: 473 SVFWSLLKNLPFLEHLELIGSNFSSAMPRNEPAIRNSLPPCSRAQSVGDSEVAAIGQLAF 532
            V    L   PFL+ + L G+     +P  +  + N  P  + A ++G + +  +GQ   
Sbjct: 186 DVVNKALSVQPFLQPVGL-GNVTLQPIPGLQ-GLPNGSPGGATAATLGLAPIQVVGQPVM 243

Query: 533 LRHLTLAQL 541
             +   +QL
Sbjct: 244 ALNTPTSQL 252


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,683,955
Number of Sequences: 37866
Number of extensions: 1162268
Number of successful extensions: 3390
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 3351
Number of HSP's gapped (non-prelim): 63
length of query: 718
length of database: 18,247,518
effective HSP length: 110
effective length of query: 608
effective length of database: 14,082,258
effective search space: 8562012864
effective search space used: 8562012864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.