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Search of human proteins with 157384973
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157384973 tenascin R [Homo sapiens]
(1358 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157384973 tenascin R [Homo sapiens] 2772 0.0
gi|62988324 tenascin N [Homo sapiens] 843 0.0
gi|153946395 tenascin C precursor [Homo sapiens] 645 0.0
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 532 e-151
gi|20665034 tenascin XB isoform 2 [Homo sapiens] 466 e-131
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 356 1e-97
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 356 1e-97
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 353 6e-97
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 353 6e-97
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 329 1e-89
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 329 1e-89
gi|223029463 fibrinogen C domain containing 1 [Homo sapiens] 216 1e-55
gi|223029461 fibrinogen C domain containing 1 [Homo sapiens] 216 1e-55
gi|8051586 ficolin 2 isoform b precursor [Homo sapiens] 212 2e-54
gi|61744445 ficolin 2 isoform a precursor [Homo sapiens] 212 2e-54
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 210 7e-54
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 210 7e-54
gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens] 207 4e-53
gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens] 206 2e-52
gi|8051584 ficolin 1 precursor [Homo sapiens] 204 5e-52
gi|23111005 microfibrillar-associated protein 4 [Homo sapiens] 194 4e-49
gi|6912236 angiopoietin-like 2 precursor [Homo sapiens] 191 4e-48
gi|4757752 angiopoietin-like 1 precursor [Homo sapiens] 187 6e-47
gi|29893555 angiopoietin-like 6 [Homo sapiens] 185 2e-46
gi|10863949 angiopoietin-like 7 [Homo sapiens] 184 4e-46
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 177 5e-44
gi|42544202 fibrinogen-like 1 precursor [Homo sapiens] 173 9e-43
gi|42544200 fibrinogen-like 1 precursor [Homo sapiens] 173 9e-43
gi|42544198 fibrinogen-like 1 precursor [Homo sapiens] 173 9e-43
gi|42544189 fibrinogen-like 1 precursor [Homo sapiens] 173 9e-43
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 2772 bits (7186), Expect = 0.0
Identities = 1358/1358 (100%), Positives = 1358/1358 (100%)
Query: 1 MGADGETVVLKNMLIGINLILLGSMIKPSECQLEVTTERVQRQSVEEEGGIANYNTSSKE 60
MGADGETVVLKNMLIGINLILLGSMIKPSECQLEVTTERVQRQSVEEEGGIANYNTSSKE
Sbjct: 1 MGADGETVVLKNMLIGINLILLGSMIKPSECQLEVTTERVQRQSVEEEGGIANYNTSSKE 60
Query: 61 QPVVFNHVYNINVPLDNLCSSGLEASAEQEVSAEDETLAEYMGQTSDHESQVTFTHRINF 120
QPVVFNHVYNINVPLDNLCSSGLEASAEQEVSAEDETLAEYMGQTSDHESQVTFTHRINF
Sbjct: 61 QPVVFNHVYNINVPLDNLCSSGLEASAEQEVSAEDETLAEYMGQTSDHESQVTFTHRINF 120
Query: 121 PKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNANCCQESAATGQLDYIPHCSGHGN 180
PKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNANCCQESAATGQLDYIPHCSGHGN
Sbjct: 121 PKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNANCCQESAATGQLDYIPHCSGHGN 180
Query: 181 FSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCS 240
FSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCS
Sbjct: 181 FSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCS 240
Query: 241 SRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNA 300
SRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNA
Sbjct: 241 SRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNA 300
Query: 301 CSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQ 360
CSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQ
Sbjct: 301 CSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQ 360
Query: 361 PTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQG 420
PTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQG
Sbjct: 361 PTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQG 420
Query: 421 LQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEY 480
LQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEY
Sbjct: 421 LQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEY 480
Query: 481 IVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGL 540
IVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGL
Sbjct: 481 IVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGL 540
Query: 541 VGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNL 600
VGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNL
Sbjct: 541 VGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNL 600
Query: 601 RVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGT 660
RVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGT
Sbjct: 601 RVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGT 660
Query: 661 EYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF 720
EYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF
Sbjct: 661 EYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF 720
Query: 721 TPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL 780
TPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL
Sbjct: 721 TPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL 780
Query: 781 HFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEY 840
HFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEY
Sbjct: 781 HFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEY 840
Query: 841 IVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRP 900
IVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRP
Sbjct: 841 IVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRP 900
Query: 901 TQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLI 960
TQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLI
Sbjct: 901 TQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLI 960
Query: 961 ATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTAT 1020
ATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTAT
Sbjct: 961 ATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTAT 1020
Query: 1021 MYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDG 1080
MYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDG
Sbjct: 1021 MYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDG 1080
Query: 1081 SRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHPQDCAQ 1140
SRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHPQDCAQ
Sbjct: 1081 SRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHPQDCAQ 1140
Query: 1141 HLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVG 1200
HLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVG
Sbjct: 1141 HLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVG 1200
Query: 1201 FGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQEAAFASYDRFSVEDSRNLYKLRIGSY 1260
FGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQEAAFASYDRFSVEDSRNLYKLRIGSY
Sbjct: 1201 FGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQEAAFASYDRFSVEDSRNLYKLRIGSY 1260
Query: 1261 NGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQG 1320
NGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQG
Sbjct: 1261 NGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQG 1320
Query: 1321 INWYHWKGHEFSIPFVEMKMRPYNHRLMAGRKRQSLQF 1358
INWYHWKGHEFSIPFVEMKMRPYNHRLMAGRKRQSLQF
Sbjct: 1321 INWYHWKGHEFSIPFVEMKMRPYNHRLMAGRKRQSLQF 1358
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 843 bits (2179), Expect = 0.0
Identities = 480/1322 (36%), Positives = 699/1322 (52%), Gaps = 83/1322 (6%)
Query: 57 SSKEQPVVFNHVYNINVPLDNLCSSGLEASAEQEVSAEDETLAEYMGQTSDHESQVTFTH 116
S+KEQ V +H Y I+VP L ++ A+ + ++D +G+ + E + F H
Sbjct: 34 SNKEQQVTVSHTYKIDVPKSAL----VQVDADPQPLSDDGASLLALGEARE-EQNIIFRH 88
Query: 117 --RINFPKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNAN-CCQESAATGQLDYIP 173
R+ P+K C A S +Q+LL+R++ LE E+ +++QC+A CCQ G D
Sbjct: 89 NIRLQTPQKDCELAGS---VQDLLARVKKLEEEMVEMKEQCSAQRCCQ-----GVTDLSR 140
Query: 174 HCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSEL 233
HCSGHG FS E+C C C EG G C L
Sbjct: 141 HCSGHGTFSLETCSCHCEEG-------------------------------REGPACERL 169
Query: 234 RCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCG 293
CP CS G CVDG C+C EPY G DC CP +CSG G C G C C E ++ EDC
Sbjct: 170 ACPGACSGHGRCVDGRCLCHEPYVGADCGYPACPENCSGHGECVRGVCQCHEDFMSEDCS 229
Query: 294 QRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVT 353
+++C CSG G C+ G C CEEG+ G DC+ V P+ L++ ++ S+ + W+ V
Sbjct: 230 EKRCPGDCSGHGFCDTGECYCEEGFTGLDCAQVVTPQGLQLLKNTEDSLLVSWEPSSQVD 289
Query: 354 EYVISYQPTA--LGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
Y++SY P L G Q+Q VP + I L PG Y +++ V + + S P
Sbjct: 290 HYLLSYYPLGKELSGKQIQ--VPKEQHSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLA 347
Query: 412 ATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVP--SDVTS- 468
T L+ TE +++V+WE S D +++ + P + VP SD S
Sbjct: 348 TTDLAVLGTAWVTDETENSLDVEWENPSTEVDYYKLRYGPMTGQEVAEVTVPKSSDPKSR 407
Query: 469 FNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPR 528
++ TGL PG EY + VV ++ + P + T ID PT ++ V++ A V W P +
Sbjct: 408 YDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQ 467
Query: 529 AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATT 588
A +D +++Y +G + S + L+PG Y+V V A RG S A T
Sbjct: 468 AVIDKYVVRY--TSADGDTKEMAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADT 525
Query: 589 QFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPT 648
TEID+P NL T + + WD +A + +Y V Y++ ++ EVLV + T
Sbjct: 526 NALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSST 585
Query: 649 TRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTK 708
LT L PG EY V + A ++S A NA T++DSP++L+ +E ++ W
Sbjct: 586 V---LTGLRPGVEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDP 642
Query: 709 ASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTV 768
ID Y + +T + G EV V K+++S LT L PG EY++ V A++G Q+S ++
Sbjct: 643 VQAAIDKYVVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADT 702
Query: 769 DAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRH 828
A T +L VT + ++W DR ++ Y+ ++ E EV + +
Sbjct: 703 KAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTSA-KDGETREVPVGKEQSS 761
Query: 829 AVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPV 888
VL GL+P EY V++ A G S+ T ID P+++ VT+++ VSW P
Sbjct: 762 TVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQ 821
Query: 889 ASFDYYRVSY-------RPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREE 941
A+ D Y V Y R VG+ SS V +T L P EY + + + +G +E
Sbjct: 822 ATIDRYVVHYTSANGETREVPVGKEQSSTV--------LTGLRPGMEYTVHVWAQKGNQE 873
Query: 942 SERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDG 1001
S++ T T +D P +L+ +T A + W ++ Y++ T + GET V
Sbjct: 874 SKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPVQATIDKYMVRYT--SADGETREVPV 931
Query: 1002 VSEEFR--LVDLLPSTHYTATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALI 1059
E L L P Y ++A G S T T LDPP NL S VT+ ++
Sbjct: 932 GKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPPRNLRPSAVTQSGGIL 991
Query: 1060 SWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSS 1119
+W PP A+I Y+LTY+ DG+ KE+ + ED L+GL + Y V L A + S
Sbjct: 992 TWTPPSAQIHGYILTYQFPDGTVKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSR 1051
Query: 1120 ITSTAFTTGGRVFPHPQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIV 1179
ST +T G FPHP DC+Q N + SG+Y I+L+G+ S+ LQVYCDM TDGGGWIV
Sbjct: 1052 NVSTTLSTVGARFPHPSDCSQVQQNSNAASGLYTIYLHGDASRPLQVYCDMETDGGGWIV 1111
Query: 1180 FQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLDNIHRIT--SQGRYELRVDMRDGQEAA 1237
FQRR GQ DFF++W Y GFG+ EFWLGLD +H +T + RYE+RVD++ E+A
Sbjct: 1112 FQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTPARYEVRVDLQTANESA 1171
Query: 1238 FASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGA 1297
+A YD F V S+ YKL +G Y GTAGD+L+YH G F+T DRDND+A++NCA+++ G
Sbjct: 1172 YAIYDFFQVASSKERYKLTVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGG 1231
Query: 1298 WWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMRP--YNHRLMAGRKRQS 1355
WWYKNCH N NG+YGE++HS+G+NW WKGHEFSIP+VE+K+RP Y+ + GRK+++
Sbjct: 1232 WWYKNCHLANPNGRYGETKHSEGVNWEPWKGHEFSIPYVELKIRPHGYSREPVLGRKKRT 1291
Query: 1356 LQ 1357
L+
Sbjct: 1292 LR 1293
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 645 bits (1665), Expect = 0.0
Identities = 337/935 (36%), Positives = 529/935 (56%), Gaps = 19/935 (2%)
Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
C+C++G+ G++C + CP CS+RG+CVDGQC+C+ ++G DC+EL CP DC +G CV+
Sbjct: 485 CVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVN 544
Query: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
G+CVC E + G+DC+E RCP DC G+GRC +G C+C EG+ G DCGQ C + C+ GQC
Sbjct: 545 GQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC 604
Query: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGL 367
G C+C EGY G DCS V+PP+DL V +++ ++ L WD M VTEY++ Y PT GGL
Sbjct: 605 VSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGL 664
Query: 368 QLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTIT 427
++Q RVPGD + I ELEPG+ Y I V+A++ N S+P++A+VAT+L P+GL+FK+I
Sbjct: 665 EMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIK 724
Query: 428 ETTVEVQWEPFSFSFDGWEISF--IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVV 485
ET+VEV+W+P +F+ WEI F + K +EG + + TS+ QTGL PG+EY +++
Sbjct: 725 ETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLH 784
Query: 486 ALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEG 545
+K R P +T +D P+QI V+DV+DT A + W P A++D I L YG+ G
Sbjct: 785 IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPG 844
Query: 546 GRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSR 605
RTT L +QYS+ L+P + YEVS+ + RG S+ A FTT +DAP+NLR S+
Sbjct: 845 DRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQ 904
Query: 606 TATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVG 665
T S+ LEW N +A + Y++ Y+ ++G + EV VP+ TT+ TLT L PGTEYG+G
Sbjct: 905 TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIG 964
Query: 666 ISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSG 725
+SAV ++S PAT+NA TELD+P+DL V+ ++ETS++L+W D YR+ ++ +G
Sbjct: 965 VSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTG 1024
Query: 726 IASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRP-ISHLHFSH 784
V +P++ TSY L LEPG EY + +TAE+GR +S + V A T P + +L +
Sbjct: 1025 QWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTE 1084
Query: 785 VTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL 844
V + + W+ + I+ ++ E +++ + R + GL+ AT Y V++
Sbjct: 1085 VGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSI 1144
Query: 845 VAVHGTVTSEPIVGSITTGIDPP-KDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ- 902
V + + +TG P ++ ++ V D++ ++W+ P +++Y+ + +
Sbjct: 1145 YGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADT 1204
Query: 903 VGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHT-AMDNPVDLIA 961
V + VP + + L AT Y I++ V + + V T + + +L
Sbjct: 1205 VEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTV 1264
Query: 962 TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE--TILVDGVSEEFRLVDLLPSTHYTA 1019
T ++ L W P G + + I + E + V G + L T YT
Sbjct: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324
Query: 1020 TMYA-----TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLT 1074
T++ + PL ++ + L D L SEV ++W E++V+
Sbjct: 1325 TLHGEVRGHSTRPLAVEVVTEDLPQLGD----LAVSEVGWDGLRLNWTAADNAYEHFVIQ 1380
Query: 1075 YKSTD--GSRKELIVDAEDTWIRLEGLLENTDYTV 1107
+ + + + L + + + GL T Y V
Sbjct: 1381 VQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRV 1415
Score = 598 bits (1542), Expect = e-170
Identities = 354/1062 (33%), Positives = 550/1062 (51%), Gaps = 31/1062 (2%)
Query: 316 EGYQGPDCSAVAPPED------LRVAGISDRSIELEWDGPMAVTEYV-ISYQPTALGGLQ 368
+GY+ P SA A + + VA + +++L W P EY I Q
Sbjct: 1149 QGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAA 1208
Query: 369 LQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITE 428
VPG + L+ Y I++ V + + P++ +V T G
Sbjct: 1209 QNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMG------NL 1262
Query: 429 TTVEVQWEPFSFSF---DGWEISFIPKNNEGGVIAQ-----VPSDVTSFNQTGLKPGEEY 480
T EV W+ ++ DG F + E + + VP + S GL+ G Y
Sbjct: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPY 1322
Query: 481 IVNVVALKEQARSPPTSASVSTVIDGPT--QILVRDVSDTVAFVEWIPPRAKVDFILLKY 538
V + + P + V T D P + V +V + W + +++
Sbjct: 1323 TVTLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQV 1381
Query: 539 GLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSV-SAVRGTNESDSATTQFTTEIDAP 597
V L L + L + Y VS+ +RG + T +
Sbjct: 1382 QEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEI 1441
Query: 598 KNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLV 657
NL V T S +L W ++ + + + + + E + G A ++ L
Sbjct: 1442 GNLNVSDITPESFNLSWMATDGIFETFTI--EIIDSNRLLETVEYNISGAERTAHISGLP 1499
Query: 658 PGTEYGVGISAVMNSQQSVPATMNARTE-LDSPRDLMVTASSETSISLIWTKASGPIDHY 716
P T++ V +S + S ++ + A TE L +L ++ + ++ W + D +
Sbjct: 1500 PSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSF 1559
Query: 717 RITFTPSSGIAS--EVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGF 774
+T S + E T+ + L L G Y + V+ Q+ + T
Sbjct: 1560 LVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA 1619
Query: 775 RP-ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMG 833
P + +L S T ++W+ D +L ++ E +E++L A +R + G
Sbjct: 1620 EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITG 1679
Query: 834 LQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDY 893
L+ ATEY + L + S+ + TT + PK++ S++T++S VSW P A +
Sbjct: 1680 LREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVES 1739
Query: 894 YRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAM 953
+R++Y P G V T T+ + +L P EY +S+ +++G EESE + TA+
Sbjct: 1740 FRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTAL 1799
Query: 954 DNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLP 1013
D P L+ NIT +EAL +W+ + V++YVI T V T V G + E+ L DL P
Sbjct: 1800 DGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEP 1859
Query: 1014 STHYTATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVL 1073
+T YT ++A GP S TI+ F+T LD P +LTA+EV ++AL++W+PPRA + Y+L
Sbjct: 1860 ATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL 1919
Query: 1074 TYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
Y+S DG+ KE+IV + T L L +T YT +QA S++ T FTT G ++P
Sbjct: 1920 VYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979
Query: 1134 HPQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRK 1193
P+DC+Q ++NGDT SG+Y I+LNG+ ++ L+V+CDMT+DGGGWIVF RR+NG+ +F++
Sbjct: 1980 FPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQN 2039
Query: 1194 WADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQEAAFASYDRFSVEDSRNLY 1253
W Y GFG+ +EFWLGLDN+++IT+QG+YELRVD+RD E AFA YD+FSV D++ Y
Sbjct: 2040 WKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRY 2099
Query: 1254 KLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYG 1313
KL++ Y+GTAGDS++YH GR FST D+D D A+TNCA+SYKGA+WY+NCHR NL G+YG
Sbjct: 2100 KLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYG 2159
Query: 1314 ESRHSQGINWYHWKGHEFSIPFVEMKMRPYNHRLMAGRKRQS 1355
++ HSQG+NW+HWKGHE SI F EMK+RP N R + GR++++
Sbjct: 2160 DNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA 2201
Score = 414 bits (1064), Expect = e-115
Identities = 287/957 (29%), Positives = 441/957 (46%), Gaps = 57/957 (5%)
Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
C C++G+ G +C E CP GCS G CV+GQC+CD Y+G+DCS+LRCP DC SRG CV+
Sbjct: 392 CECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVE 451
Query: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
G+CVCE+ + G DC ++ CP DC GRC NG C+C++GY GEDC RQC CS RG C
Sbjct: 452 GKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLC 511
Query: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGL 367
+G CVCE+G+ GPDC+ ++ P D G V + ++ +G
Sbjct: 512 VDGQCVCEDGFTGPDCAELSCPNDCHGQG-------------RCVNGQCVCHE-GFMGKD 557
Query: 368 QLQQRVPGDWSG------------VTITELE------PGLTYNISVYAVISNILSLPITA 409
+QR P D G T L+ P N+ I + +
Sbjct: 558 CKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSG 617
Query: 410 KVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQ--VPSDVT 467
+ + +S P+ L +TE TV + W+ + + + P +EGG+ Q VP D T
Sbjct: 618 EDCSEVSPPKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTP-THEGGLEMQFRVPGDQT 675
Query: 468 SFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIP- 526
S L+PG EY + V A+ E +S P SA V+T + P + + + +T VEW P
Sbjct: 676 STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735
Query: 527 PRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSA 586
A + ++ + + G T L+ P + Y L PG YE+S+ V+
Sbjct: 736 DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795
Query: 587 TTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVY--STLAGEQYHEVLVPRG 644
TT +DAP + V T T+ + W AE+ ++ Y + G++ L
Sbjct: 796 KRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTE-- 853
Query: 645 IGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISL 704
+ ++ +L P TEY V + + S PA T LD+PR+L + ++ SI+L
Sbjct: 854 --DENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911
Query: 705 IWTKASGPIDHYRITFTP-SSGIASEVTVPKDR---TSYTLTDLEPGAEYIISVTAERGR 760
W ID YRI + P S G +EV VPK + T TLT L PG EY I V+A +
Sbjct: 912 EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971
Query: 761 QQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEV 820
++S +T++A T L S +S+ + W P DR LNYS + + V
Sbjct: 972 KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSL--PTGQWVGV 1029
Query: 821 SLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPP-KDITISNVTKDS 879
L VL GL+P EY V L A G S+P +T P +++T++ V D
Sbjct: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDG 1089
Query: 880 VMVSWSPPVASFDYYRVSYR-PTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRG 938
+ ++W+ +++++ + + +V + VP ++ I L AT Y +S+ V
Sbjct: 1090 LRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQ 1149
Query: 939 REESERICTLVHTA-MDNPVDLIATNITPTEALLQWKAPVGEVENYVIVL--THFAVAGE 995
+ + T N +++ + L W AP G E + I + A +
Sbjct: 1150 GYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209
Query: 996 TILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLLDPP-ANLTASEVTR 1054
+ V G L L +THYT T+ ++ +S T P NLT +EV+
Sbjct: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSW 1269
Query: 1055 QSALISWQPPRAEIENYVLTYKSTDGSRK--ELIVDAEDTWIRLEGLLENTDYTVLL 1109
+ ++W P + + + + D + L V + + GL T YTV L
Sbjct: 1270 DALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326
Score = 314 bits (805), Expect = 3e-85
Identities = 145/283 (51%), Positives = 187/283 (66%), Gaps = 6/283 (2%)
Query: 53 NYNTSSKEQPVVFNHVYNINVPLDNLCSSGLE-ASAEQEVSAEDETLAEYMGQTSDHESQ 111
N + QPVVFNHVYNI +P+ + CS LE AS E++++ E + T D E+Q
Sbjct: 38 NATLPEENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQ 97
Query: 112 VTFTHRINFPKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNAN--CCQESAATGQL 169
+ FTHRIN P++AC CA++ V +ELLSR+E LE VS LR+QC A CC + A TG+L
Sbjct: 98 IVFTHRINIPRRACGCAAAPDV-KELLSRLEELENLVSSLREQCTAGAGCCLQPA-TGRL 155
Query: 170 DYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDD 229
D P CSG GNFS E CGC+C GW G NCSEP CP C RG C+DGQCICD ++G+D
Sbjct: 156 DTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGED 215
Query: 230 CSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGK-GRCANGTCLCEEGYV 288
CS+L CP+DC+ +G CV+G C+C E Y G DC CP CS + G C +G C+C +G+
Sbjct: 216 CSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFA 275
Query: 289 GEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPED 331
G+DC + CLN C RG+C E CVC+EG+ G DCS + P D
Sbjct: 276 GDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPND 318
Score = 207 bits (526), Expect = 7e-53
Identities = 81/149 (54%), Positives = 105/149 (70%)
Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
C C EG+ G++C +P CP C ++G C +GQC+CD ++G DCSE RCP DC +RG CVD
Sbjct: 330 CYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVD 389
Query: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
G C C++ +TG DC EL+CP CSG GRC NG C+C+EGY GEDC Q +C N C RG+C
Sbjct: 390 GRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRC 449
Query: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
EG CVCE+G++G DCS ++ P D G
Sbjct: 450 VEGKCVCEQGFKGYDCSDMSCPNDCHQHG 478
Score = 188 bits (477), Expect = 3e-47
Identities = 71/149 (47%), Positives = 99/149 (66%)
Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
C+C+EG+ G++CSE CP C RG C++G C C+ ++G+DC + CP C ++G C +
Sbjct: 299 CVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEE 358
Query: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
G+CVC+E + G DC E RCP DC +GRC +G C C++G+ G DCG+ +C N CSG G+C
Sbjct: 359 GQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC 418
Query: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
G CVC+EGY G DCS + P D G
Sbjct: 419 VNGQCVCDEGYTGEDCSQLRCPNDCHSRG 447
Score = 152 bits (385), Expect = 2e-36
Identities = 120/438 (27%), Positives = 191/438 (43%), Gaps = 13/438 (2%)
Query: 684 TELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTSYTL 741
+E+ P+DL+VT +E +++L W + Y + +TP+ G+ + VP D+TS +
Sbjct: 621 SEVSPPKDLVVTEVTEETVNLAWDNEMR-VTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
Query: 742 TDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPA 801
+LEPG EY I V A ++S+ + T L F + +SV + W DP A
Sbjct: 680 QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEW-DPLDIA 738
Query: 802 DRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGS 859
I+ + E+E + SL + GL P EY ++L V +
Sbjct: 739 FETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRV 798
Query: 860 ITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEF 918
TT +D P I + +VT + +++W P+A D ++Y V G + + ++
Sbjct: 799 TTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
Query: 919 TITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVG 978
+I L P TEYE+SL S RG S T +D P +L + T L+W+
Sbjct: 859 SIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918
Query: 979 EVENYVIVLTHFAVAGETILVD-----GVSEEFRLVDLLPSTHYTATMYATNGPLTSGTI 1033
+++Y I + G+ VD + + L L P T Y + A S
Sbjct: 919 AIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPA 977
Query: 1034 STNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTW 1093
+ N +T LD P +L SE S + W+ P A+ + Y L Y G + + T
Sbjct: 978 TINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTS 1037
Query: 1094 IRLEGLLENTDYTVLLQA 1111
L GL +Y VLL A
Sbjct: 1038 YVLRGLEPGQEYNVLLTA 1055
Score = 95.9 bits (237), Expect = 2e-19
Identities = 71/284 (25%), Positives = 123/284 (43%), Gaps = 7/284 (2%)
Query: 851 VTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSV 910
+ +E G + + PPKD+ ++ VT+++V ++W + +Y V Y PT G L+
Sbjct: 610 ICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYL-VVYTPTHEGGLEMQF 668
Query: 911 -VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969
VP T I L P EY I + ++ ++S + V T + P L +I T
Sbjct: 669 RVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSV 728
Query: 970 LLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSE---EFRLVDLLPSTHYTATMYATNG 1026
++W E + I+ + E + + +R L P Y +++
Sbjct: 729 EVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKN 788
Query: 1027 PLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY--KSTDGSRKE 1084
+ +T LD P+ + +VT +ALI+W P AEI+ LTY K G R
Sbjct: 789 NTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTT 848
Query: 1085 LIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTG 1128
+ + ++ + L +T+Y V L + + S+ FTTG
Sbjct: 849 IDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTG 892
Score = 72.0 bits (175), Expect = 4e-12
Identities = 37/100 (37%), Positives = 52/100 (52%), Gaps = 8/100 (8%)
Query: 240 SSRGLCVDGECVCEEPYTGE-DCRELRCPGDCSGKGRCANGTC--LCEEGYVGEDCGQRQ 296
S R C G C +P TG D R CSG+G + C +CE G+ G +C + +
Sbjct: 135 SLREQCTAGAGCCLQPATGRLDTRPF-----CSGRGNFSTEGCGCVCEPGWKGPNCSEPE 189
Query: 297 CLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
C C RG+C +G C+C++G+ G DCS +A P D G
Sbjct: 190 CPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQG 229
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 532 bits (1371), Expect = e-151
Identities = 341/1096 (31%), Positives = 517/1096 (47%), Gaps = 75/1096 (6%)
Query: 321 PDCSAVAPPED-----LRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVP 374
P A PE+ L V G S S+ L W P + + Y+ G RV
Sbjct: 3154 PSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDR--DGQPQVVRVR 3211
Query: 375 GDWSGVTITELEPGLTYNISVYAV-----ISNILSLPITAKVATHLSTPQGL---QFKTI 426
G+ S VT+ LEPG Y + +Y + + + ++ ITA + T L L +
Sbjct: 3212 GEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAV 3271
Query: 427 TETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVA 486
T +V + W FD + + + + + V D+ + +GL P +Y +
Sbjct: 3272 TSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAVP-VSGDLRAVAVSGLDPARKYKFLLFG 3330
Query: 487 LKEQARSPPTSASVSTVIDGPT-----QILVRDVSDTVAFVEWIPPRAKVDFILLKYGLV 541
L+ R P T D ++ V D + + W P + D +++Y
Sbjct: 3331 LQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYK-- 3388
Query: 542 GGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPK 598
+G + + +VQ L P +Y + + G + TT E + P
Sbjct: 3389 DKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPP 3448
Query: 599 NL---RVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTD 655
+L V T++SL L W ++ + V Y G+ VP T T+ D
Sbjct: 3449 HLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPR---AVPVAADQRT-VTVED 3504
Query: 656 LVPGTEYGVGISAVMNSQQSVPATMNART--ELDSPRD-----------------LMVTA 696
L PG +Y + ++ ++ P + T E D+P L VT
Sbjct: 3505 LEPGKKYKFLLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTD 3564
Query: 697 SSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTA 756
++ S+ L W+ A GP D + + + ++G + V D++ ++ LEP Y +
Sbjct: 3565 TTPDSMRLSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYG 3624
Query: 757 ERGRQQSLESTVDAFTGFRP-----------ISHLHFSHVTSSSVNITWSDPSPPADRLI 805
++ + + TG P +S L + VT+SS+ + W P D +
Sbjct: 3625 LHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFL 3684
Query: 806 LNYS--------PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIV 857
L + P E+ + T+ AVL L+ T Y + L + G ++ I
Sbjct: 3685 LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQ 3744
Query: 858 GSITT---GIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNT 914
G+ T ++ P+D+ S + + S V+W PP + D ++VSY+ G S V
Sbjct: 3745 GTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQ 3804
Query: 915 VTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWK 974
+ L P YE+++ SVRG EESE + + T D P L A N+T A+L WK
Sbjct: 3805 ARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWK 3864
Query: 975 APVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTIS 1034
P V+ Y + +T G + ++ L DL+ T+YTAT+ GP + S
Sbjct: 3865 PPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPAS 3924
Query: 1035 TNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWI 1094
F+T L+ P +L A EVT ++AL++W P Y+L++ + G +E+++ T
Sbjct: 3925 ITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSH 3984
Query: 1095 RLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHPQDCAQHLMNGDTLSGVYPI 1154
+L GL +T Y LQA + ST+FTTGG P P+DC + + NG S I
Sbjct: 3985 QLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTI 4044
Query: 1155 FLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLDN 1214
FLNG + L V+CDM TDGGGW+VFQRR +GQTDF+R W DY GFGN+ EFWLG +
Sbjct: 4045 FLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEA 4104
Query: 1215 IHRITSQGRYELRVDMRDGQEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGR 1274
+H +T G Y +RVD+R G EA FA YD F V+ + Y+L + Y+GTAGDS+SYH G
Sbjct: 4105 LHSLTQAGDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGS 4164
Query: 1275 PFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIP 1334
FS DRD + + +CA+SY+GAWWY+NCH NLNG YG + QG++WYHWKG EFS+P
Sbjct: 4165 VFSARDRDPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVP 4224
Query: 1335 FVEMKMRPYNHRLMAG 1350
F EMK+RP N R AG
Sbjct: 4225 FTEMKLRPRNFRSPAG 4240
Score = 364 bits (935), Expect = e-100
Identities = 285/1060 (26%), Positives = 436/1060 (41%), Gaps = 157/1060 (14%)
Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
C+CN G+ G++C CP C G+C DG C+CD+ YSG+DCS CP C RG C+D
Sbjct: 512 CVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLD 571
Query: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
G CVCE+ Y+GEDC +CP DCS G C +G C+C EGYV EDC R C + C GRG+C
Sbjct: 572 GRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRC 631
Query: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDG----PMAVTEYVISYQPTA 363
EEG C+C+ GY GP C+ P D R G + + L G E S P
Sbjct: 632 EEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGG 691
Query: 364 LGGLQL------------------QQRVPGDWSGVTITELEPGLTYNISVYAVISNILSL 405
G +L Q PGD G E G YA
Sbjct: 692 CGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRG--RGECHDGSCVCKDGYA-------- 741
Query: 406 PITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGG---VIAQV 462
+ T +G++ + ETTV +W P D +EI FIP EG A+V
Sbjct: 742 --GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIP-TTEGASPPFTARV 798
Query: 463 PSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFV 522
PS ++++Q GL PG+EY V V AL+ + P S +++T+IDGP + V V+ T +
Sbjct: 799 PSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLEL 858
Query: 523 EWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRG--- 579
W+ P+A+VD ++ Y G + R + P + L PG Y V+V+A RG
Sbjct: 859 GWLRPQAEVDRFVVSYVSAGNQ--RVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAV 916
Query: 580 --------------------TNESDSATTQFTTEIDAP---------KNLRVGSRTATS- 609
T+E + T AP LRV R T
Sbjct: 917 SYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGR 976
Query: 610 LDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGI--- 666
L + W +++ G HE ++P G +A + PGT Y + +
Sbjct: 977 LRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLP---GDVRQALVPPPPPGTPYELSLHGV 1033
Query: 667 ------------SAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPID 714
+M+ + P + L +L VT + S+ L WT G D
Sbjct: 1034 PPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLG---ELTVTDRTSDSLLLRWTVPEGEFD 1090
Query: 715 HYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQ--------SLES 766
+ I + G V V + S +T L+PG +Y + G+++ +
Sbjct: 1091 SFVIQYKDRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILP 1150
Query: 767 TVDAFTGFRP-ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDAT 825
D G P + +L + T S++++W+ P D ++ Y RD ++ V ++
Sbjct: 1151 QSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQV--VPVEGP 1208
Query: 826 KRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTG----IDPPK----------DIT 871
+R V+ L P +Y L + P+ TT +PP+ ++T
Sbjct: 1209 ERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELT 1268
Query: 872 ISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEI 931
++ VT DS+ +SW+ FD + V Y+ Q G+ + V E T+ L+P +Y++
Sbjct: 1269 VTGVTPDSLRLSWTVAQGPFDSFMVQYKDAQ-GQPQAVPVAGDENEVTVPGLDPDRKYKM 1327
Query: 932 SLNSVRGREESERICTLVHTAMDNPVD-----------------------LIATNITPTE 968
+L +RGR+ + TA VD L T +P
Sbjct: 1328 NLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDS 1387
Query: 969 ALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPL 1028
L W P G +++ + + V G E + L P Y +Y +
Sbjct: 1388 LSLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQ 1447
Query: 1029 TSGTISTNFSTLLD----PPA----------NLTASEVTRQSALISWQPPRAEIENYVLT 1074
G +S T PPA LT ++VT S +SW P + +++++
Sbjct: 1448 RVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQ 1507
Query: 1075 YKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
YK DG + + V A+ + + L Y + + D
Sbjct: 1508 YKDKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHD 1547
Score = 350 bits (898), Expect = 5e-96
Identities = 293/1150 (25%), Positives = 451/1150 (39%), Gaps = 209/1150 (18%)
Query: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
C GHG E C+C+ G+ G++CS CP GC RG C+DG+C+C+ YSG+DC +
Sbjct: 532 CRGHG--LCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQ 589
Query: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCR-------------------------------E 263
CP DCS G+C DG C+C E Y EDC
Sbjct: 590 CPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCAT 649
Query: 264 LRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQ--------------------------- 296
CP DC G+GRC G CLC GY GEDCGQ +
Sbjct: 650 RMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAGQCVCVEGF 709
Query: 297 ---------CLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPP-EDLRVAGISDRSIELEW 346
C C GRG+C +G CVC++GY G DC P E +R+ + + ++ EW
Sbjct: 710 RGPDCAIQTCPGDCRGRGECHDGSCVCKDGYAGEDCGEEVPTIEGMRMHLLEETTVRTEW 769
Query: 347 -DGPMAVTEYVISYQPTALGGL-QLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILS 404
P V Y I + PT G RVP S L PG Y ++V A+
Sbjct: 770 TPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWG 829
Query: 405 LPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
LP + + T + PQ L+ +T TT+E+ W D + +S++ N+ V +VP
Sbjct: 830 LPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGNQ-RVRLEVPP 888
Query: 465 DVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVID------------------- 505
+ T L PG EY+V V A + +A S P S +T
Sbjct: 889 EADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTT 948
Query: 506 ---------------GPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTF 550
G ++L RD + + V W + L+ + G G
Sbjct: 949 QGAQAPLLQQRPQELGELRVLGRDETGRLRVV-WTAQPDTFAYFQLRMRVPEGPGAHEEV 1007
Query: 551 RLQPPLSQYSVQALRPGSRYEVSVSAV-RGTNESDSATTQFTTEIDAPK----------- 598
L + Q V PG+ YE+S+ V G SD Q + D K
Sbjct: 1008 -LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLG 1066
Query: 599 NLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVP 658
L V RT+ SL L W E E + + Y G+ +VP GP A +T L P
Sbjct: 1067 ELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQ---VVPVE-GPQRSAVITSLDP 1122
Query: 659 GTEYGVGISAVMNSQQSVPATMNARTELDSP---------RDLMVTASSETSISLIWTKA 709
G +Y + + ++ P A+ S +L VT + S+ L WT
Sbjct: 1123 GRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVP 1182
Query: 710 SGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVD 769
G D + + + G V V S+ ++ L+P +Y ++ +++ T D
Sbjct: 1183 EGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGPLTAD 1242
Query: 770 AFTG-------FRP-------ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEE 815
T RP + L + VT S+ ++W+ P D ++ Y +D +
Sbjct: 1243 GTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQY--KDAQG 1300
Query: 816 EMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHG--TVTSEPIVGSIT------------ 861
+ V + + + GL P +Y +NL + G V E +V
Sbjct: 1301 QPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPT 1360
Query: 862 -TGIDPPK--------DITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVP 912
G + P+ ++T++ + DS+ + W+ P SFD + V Y+ GR + V
Sbjct: 1361 ELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRD-GRPRAVRVG 1419
Query: 913 NTVTEFTITRLNPATEYEISLNSVRGREESERICTL------------VHTAMDNPV--- 957
+E T+ L P +Y++ L G E +R+ + A ++P+
Sbjct: 1420 GKESEVTVGGLEPGHKYKMHL---YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPR 1476
Query: 958 --DLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPST 1015
+L T++TP L W P G+ +++++ + + V E + +L P
Sbjct: 1477 LGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTVYNLEPER 1536
Query: 1016 HYTATMYATNGPLTSGTISTNFSTLLDPPA---------------NLTASEVTRQSALIS 1060
Y MY + G +S T PPA LT +++T S +S
Sbjct: 1537 KYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLS 1596
Query: 1061 WQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSI 1120
W P E +++V+ YK DG + + V A+ + + L + Y LL QD S
Sbjct: 1597 WTVPEGEFDSFVVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSP 1656
Query: 1121 TSTAFTTGGR 1130
S T R
Sbjct: 1657 VSVEAKTVAR 1666
Score = 221 bits (563), Expect = 4e-57
Identities = 107/245 (43%), Positives = 127/245 (51%), Gaps = 24/245 (9%)
Query: 109 ESQVTFTHRINFPKKA---CPCASSAQVL----QELLSRIEMLEREVSVLRDQCNANCCQ 161
E QV FTHRIN P CP + VL Q L R+E+LE V L++QC CC
Sbjct: 68 EKQVVFTHRINLPPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCP 127
Query: 162 ESA--ATGQLDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPY---------------C 204
SA TGQ D CS HG F C C C GW G CS+P C
Sbjct: 128 ASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSC 187
Query: 205 PLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCREL 264
P C+ +G CV G+C+C Y+G C CP DC RG CV G CVC ++G DC +
Sbjct: 188 PDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQR 247
Query: 265 RCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCS 324
CP CS +GRC G C+C+ GY G+DCG R C CS RG+CE G CVC GY G DC
Sbjct: 248 SCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCG 307
Query: 325 AVAPP 329
+ P
Sbjct: 308 VRSCP 312
Score = 197 bits (501), Expect = 6e-50
Identities = 83/168 (49%), Positives = 103/168 (61%), Gaps = 2/168 (1%)
Query: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
CS G E+ C+CN G+ G++C CP GCS RG C DG+C+CD Y+G+DC
Sbjct: 284 CSQRGRC--ENGRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRS 341
Query: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQ 294
CP DC G CVDG CVC YTGEDC CP DC G+GRC +G C+C+ GY G+DCG
Sbjct: 342 CPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGV 401
Query: 295 RQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSI 342
R C C+ RG+CE+G CVC GY G DC + A P D R G + +
Sbjct: 402 RSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRCENGV 449
Score = 194 bits (493), Expect = 5e-49
Identities = 82/174 (47%), Positives = 100/174 (57%), Gaps = 2/174 (1%)
Query: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
C G G E+ C+CN G+ G++C CP C RG C G+C+C Y+G DC
Sbjct: 439 CRGRGRC--ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRA 496
Query: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQ 294
CP DC RG CVDG CVC +TGEDC RCPGDC G G C +G C+C+ GY GEDC
Sbjct: 497 CPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCST 556
Query: 295 RQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDG 348
R C C GRGQC +G CVCE+GY G DC P D G+ + + W+G
Sbjct: 557 RSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEG 610
Score = 192 bits (489), Expect = 1e-48
Identities = 81/149 (54%), Positives = 92/149 (61%)
Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
C+C G+ G++CS CP C RG C DG+CICD+ YSGDDC CP DC+ RG C D
Sbjct: 357 CVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCED 416
Query: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
G CVC YTG DC CP DC G+GRC NG C+C GY GEDCG R C C GRG+C
Sbjct: 417 GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRC 476
Query: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
E G C+C GY G DC A P D R G
Sbjct: 477 ESGRCMCWPGYTGRDCGTRACPGDCRGRG 505
Score = 192 bits (487), Expect = 2e-48
Identities = 84/188 (44%), Positives = 111/188 (59%), Gaps = 3/188 (1%)
Query: 152 RDQC-NANCCQESAATGQLDYIPHCSG--HGNFSFESCGCICNEGWFGKNCSEPYCPLGC 208
R +C N C + +G+ + C G G ES C+C G+ G++C CP C
Sbjct: 442 RGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDC 501
Query: 209 SSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPG 268
RG CVDG+C+C+ ++G+DC RCP DC GLC DG CVC+ Y+GEDC CPG
Sbjct: 502 RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPG 561
Query: 269 DCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAP 328
C G+G+C +G C+CE+GY GEDCG RQC N CS G C++G+C+C EGY DCS
Sbjct: 562 GCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTC 621
Query: 329 PEDLRVAG 336
P + G
Sbjct: 622 PSNCHGRG 629
Score = 189 bits (481), Expect = 1e-47
Identities = 76/161 (47%), Positives = 98/161 (60%)
Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
C+C+ G+ G++C CP C G CVDG+C+C Y+G+DCS CP DC RG C D
Sbjct: 326 CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCED 385
Query: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
GEC+C+ Y+G+DC CPGDC+ +GRC +G C+C GY G DCG R C C GRG+C
Sbjct: 386 GECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGRGRC 445
Query: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDG 348
E G+CVC GY G DC + P D R G + + W G
Sbjct: 446 ENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPG 486
Score = 186 bits (473), Expect = 1e-46
Identities = 83/191 (43%), Positives = 104/191 (54%), Gaps = 9/191 (4%)
Query: 158 NCCQESAATGQLDYIPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDG 217
+C Q S G CS G E C+C+ G+ G +C CP GCS RG C +G
Sbjct: 243 DCSQRSCPRG-------CSQRGRC--EGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENG 293
Query: 218 QCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCA 277
+C+C+ Y+G+DC CP CS RG C DG CVC+ YTGEDC CP DC GRC
Sbjct: 294 RCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRCV 353
Query: 278 NGTCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGI 337
+G C+C GY GEDC R C C GRG+CE+G C+C+ GY G DC + P D G
Sbjct: 354 DGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGR 413
Query: 338 SDRSIELEWDG 348
+ + W G
Sbjct: 414 CEDGRCVCWPG 424
Score = 186 bits (472), Expect = 1e-46
Identities = 211/900 (23%), Positives = 359/900 (39%), Gaps = 138/900 (15%)
Query: 331 DLRVAGISDRSIELEWDGPMAVTE-YVISY-----QPTALGGLQLQQRVPGDWSGVTITE 384
+L + + S+ L W P + +++ Y QP A+ RVPG GVTI+
Sbjct: 2633 ELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAV-------RVPGHEDGVTISG 2685
Query: 385 LEPGLTYNISVYAV-----ISNILSLPITAKVA-----THLST--PQGLQFKTITETTV- 431
LEP Y +++Y + I + +TA T LST P+ + + E TV
Sbjct: 2686 LEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVT 2745
Query: 432 -------EVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNV 484
+ W FD + + + ++ V+ +V + + GL+PG +Y +++
Sbjct: 2746 GSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVM-RVRGEESEVTVGGLEPGRKYKMHL 2804
Query: 485 VALKEQARSPP------------TSASVSTVIDGPT------QILVRDVSDTVAFVEWIP 526
L E R P T+ +V T P ++ V D + + W+
Sbjct: 2805 YGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMV 2864
Query: 527 PRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYE--------------V 572
P + D L++Y G+G R+ ++ L P +Y+ +
Sbjct: 2865 PEGQFDHFLVQYR--NGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPI 2922
Query: 573 SVSAVRGTNESDSATTQFTTEI-DAPKNLRVGSRTAT-----SLDLEWDNSEAEVQEYKV 626
SV V E A T+ +TE + P+ +G T T SL L W + + V
Sbjct: 2923 SVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTV 2982
Query: 627 VYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEY-----------------GVGISAV 669
Y G V R G + T+ L PG +Y VG++A
Sbjct: 2983 QYKDRDGRPQ----VVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAP 3038
Query: 670 MNSQQSVPATMNARTELD-SPR--DLMVTASSETSISLIWTKASGPIDHYRITFTPSSGI 726
+ ++ A E PR +L VT ++ S+SL W G DH+ + + G
Sbjct: 3039 KDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQ 3098
Query: 727 ASEVTVPKDRTSYTLTDLEPGAEY-----------------IISVTAERGRQQSLESTVD 769
V VP T++ LEP +Y I VT E + ST
Sbjct: 3099 PKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEA 3158
Query: 770 AFTGFRP-ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRH 828
P + L + + S++++W+ P D + Y RD + +++ V +
Sbjct: 3159 PEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVR--GEESE 3216
Query: 829 AVLMGLQPATEYIVNLVAVH-----GTVTSEPIVGSITTGID-PPK--DITISNVTKDSV 880
+ GL+P +Y ++L +H G V++ I + T + P+ ++ ++ VT DSV
Sbjct: 3217 VTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSV 3276
Query: 881 MVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGRE 940
+SW+ FD + V YR Q G+ + V + ++ L+PA +Y+ L ++ +
Sbjct: 3277 GLSWTVAQGPFDSFLVQYRDAQ-GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGK 3335
Query: 941 ESERICTLVHTAMDNPV-----DLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE 995
+ TA D +L T+ TP L W P GE +++V+ +
Sbjct: 3336 RHGPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGRLQ 3395
Query: 996 TILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTL-LD---PP--ANLTA 1049
+ V E + L PS Y +Y +G G IS + +T L+ PP LT
Sbjct: 3396 VVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTV 3455
Query: 1050 SEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLL 1109
+E T S +SW + +++V+ Y+ TDG + + V A+ + +E L Y LL
Sbjct: 3456 AEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLL 3515
Score = 182 bits (462), Expect = 2e-45
Identities = 76/149 (51%), Positives = 90/149 (60%)
Query: 188 CICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVD 247
C+C G+ G +CS+ CP GCS RG C G+C+CD Y+GDDC CP CS RG C +
Sbjct: 233 CVCRAGFSGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCEN 292
Query: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQC 307
G CVC YTGEDC CP CS +GRC +G C+C+ GY GEDCG R C C G+C
Sbjct: 293 GRCVCNPGYTGEDCGVRSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTRSCPWDCGEGGRC 352
Query: 308 EEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
+G CVC GY G DCS P D R G
Sbjct: 353 VDGRCVCWPGYTGEDCSTRTCPRDCRGRG 381
Score = 182 bits (462), Expect = 2e-45
Identities = 80/188 (42%), Positives = 104/188 (55%), Gaps = 3/188 (1%)
Query: 152 RDQC-NANCCQESAATGQLDYIPHCSGHGNFS--FESCGCICNEGWFGKNCSEPYCPLGC 208
R +C + C ++ +G + C G N E C+C G+ G +C CP C
Sbjct: 380 RGRCEDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDC 439
Query: 209 SSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPG 268
RG C +G C+C++ YSG+DC CP DC RG C G C+C YTG DC CPG
Sbjct: 440 RGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPG 499
Query: 269 DCSGKGRCANGTCLCEEGYVGEDCGQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAP 328
DC G+GRC +G C+C G+ GEDCG R+C C G G CE+G+CVC+ GY G DCS +
Sbjct: 500 DCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSC 559
Query: 329 PEDLRVAG 336
P R G
Sbjct: 560 PGGCRGRG 567
Score = 181 bits (460), Expect = 3e-45
Identities = 77/168 (45%), Positives = 96/168 (57%), Gaps = 2/168 (1%)
Query: 175 CSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELR 234
C G G E CIC+ G+ G +C CP C+ RG C DG+C+C Y+G DC
Sbjct: 377 CRGRGRC--EDGECICDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRA 434
Query: 235 CPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQ 294
CP DC RG C +G CVC Y+GEDC CPGDC G+GRC +G C+C GY G DCG
Sbjct: 435 CPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGT 494
Query: 295 RQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSI 342
R C C GRG+C +G CVC G+ G DC + P D R G+ + +
Sbjct: 495 RACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGV 542
Score = 159 bits (401), Expect = 2e-38
Identities = 200/939 (21%), Positives = 353/939 (37%), Gaps = 173/939 (18%)
Query: 332 LRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY 391
+ V I+ S+ L W P ++ + G RVPG GVTI+ LEP Y
Sbjct: 2200 MTVRDITSDSLSLSWTVPEGQFDHFLVQFKNG-DGQPKAVRVPGHEDGVTISGLEPDHKY 2258
Query: 392 NISVYAV-----ISNILSLPITAK--------VATHLSTPQG-----LQFKTITETT--- 430
+++Y + + ++ +TA +T TP+ L+ T+T+ T
Sbjct: 2259 KMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDS 2318
Query: 431 VEVQWEPFSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKE 489
+ + W FD + + + KN +G A +VP +GL+P +Y +N+
Sbjct: 2319 LSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHG 2376
Query: 490 QARSPPTSASVSTVIDGPT--------------------QILVRDVSDTVAFVEWIPPRA 529
R P SA T + T ++ V S + W P+
Sbjct: 2377 GQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQG 2436
Query: 530 KVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVS------------VSAV 577
+ D ++Y +G R+ S+ +V L PG +Y++ VS V
Sbjct: 2437 RFDSFTVQYK--DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2494
Query: 578 RGT------NESDSATTQFTTEIDAPKNLRVGSRTAT-----SLDLEWDNSEAEVQEYKV 626
T +E+ S T T P+ +G T T SL L W + + V
Sbjct: 2495 GVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTV 2554
Query: 627 VYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTEL 686
Y G R G ++ T+ L PG +Y + + + ++ P + TE
Sbjct: 2555 QYKDRDGRPQ----AVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTED 2610
Query: 687 DS----------------PR--DLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIAS 728
++ PR +L +T ++ S+SL WT G DH+ + + G
Sbjct: 2611 EAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPK 2670
Query: 729 EVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRP------------ 776
V VP T++ LEP +Y +++ G Q+ +V T
Sbjct: 2671 AVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEA 2730
Query: 777 --------ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRH 828
+ L + + S++++W+ P D + Y RD ++M V +
Sbjct: 2731 PEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMRVR--GEESE 2788
Query: 829 AVLMGLQPATEYIVNLVAVH-----GTVT--------SEPIVGSITTGIDPPK-----DI 870
+ GL+P +Y ++L +H G V+ +E TT +PP ++
Sbjct: 2789 VTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGEL 2848
Query: 871 TISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYE 930
T+++ T DS+ +SW P FD++ V YR G+ VP TI+ L P +Y+
Sbjct: 2849 TVTDATPDSLSLSWMVPEGQFDHFLVQYRNGD-GQPKVVRVPGHEDGVTISGLEPDHKYK 2907
Query: 931 ISLNSVRGREESERICTLVHTAMDNPV--------------------DLIATNITPTEAL 970
++L G + I + TA + +L T +P
Sbjct: 2908 MNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLS 2967
Query: 971 LQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATN----- 1025
L W P G +++ + + + V G E + L P Y +Y +
Sbjct: 2968 LSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRV 3027
Query: 1026 GPLT----------SGTISTNFSTLLDPP-----ANLTASEVTRQSALISWQPPRAEIEN 1070
GP++ + T + +PP LT ++ T S +SW P + ++
Sbjct: 3028 GPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDH 3087
Query: 1071 YVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLL 1109
+++ Y++ DG K + V + + + GL + Y + L
Sbjct: 3088 FLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNL 3126
Score = 157 bits (396), Expect = 9e-38
Identities = 193/926 (20%), Positives = 348/926 (37%), Gaps = 150/926 (16%)
Query: 321 PDCSAVAPP-----EDLRVAGISDRSIELEWDGPMAVTE-YVISYQPTALGGLQLQQRVP 374
P A PP +L V I+ S+ L W P + +V+ Y+ G V
Sbjct: 1567 PATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPVA 1624
Query: 375 GDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHL------STPQGLQFKTITE 428
D VTI +LEP Y ++ + P++ + T P L +T+
Sbjct: 1625 ADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTD 1684
Query: 429 TT---VEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVV 485
T + + W FD + + F K+ +G + V S T L G +Y +
Sbjct: 1685 PTPDSLRLSWTVPEGQFDSFVVQF--KDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLY 1742
Query: 486 ALKEQARSPPTSASVST-----VIDGPT----------QILVRDVSDTVAFVEWIPPRAK 530
L + R P +A +T + D T ++ V V+ + W P +
Sbjct: 1743 GLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQ 1802
Query: 531 VDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEV---------------SVS 575
D +++Y +G ++ L + SV L P RY++ +V+
Sbjct: 1803 FDSFVVQYK--DRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA 1860
Query: 576 AVRGTNESDSATTQFTTEIDAPK--NLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAG 633
G E+++ TT T P L V T+ +L L W +E E +++ Y+ G
Sbjct: 1861 ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG 1920
Query: 634 EQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNART--ELDSPRD 691
+ + + R G TL+ L Y V + + + P + A T E + P +
Sbjct: 1921 Q----LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSE 1976
Query: 692 ----------------LMVTASSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPKD 735
L VT ++ S+SL WT G DH+ + + G V VP
Sbjct: 1977 PPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGH 2036
Query: 736 RTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRP------------------- 776
T++ LEP +Y +++ G Q+ +V T
Sbjct: 2037 EEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEP 2096
Query: 777 -ISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQ 835
+ L + + S++++W+ P D + Y RD +++ V + + GL+
Sbjct: 2097 LLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVG--GEESEVTVGGLE 2154
Query: 836 PATEYIVNLVAVH-----GTVTSEPIVGSITTGIDPP------KDITISNVTKDSVMVSW 884
P +Y ++L +H G V++ + D P +T+ ++T DS+ +SW
Sbjct: 2155 PGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSW 2214
Query: 885 SPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESER 944
+ P FD++ V ++ G+ + VP TI+ L P +Y+++L G +
Sbjct: 2215 TVPEGQFDHFLVQFKNGD-GQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGP 2273
Query: 945 ICTLVHTA----------------MDNPV-----DLIATNITPTEALLQWKAPVGEVENY 983
+ + TA + P+ +L T+ TP L W P G+ +++
Sbjct: 2274 VSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHF 2333
Query: 984 VIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLL-- 1041
++ + + V G + + L P Y +Y +G G +S T
Sbjct: 2334 LVQYKNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEE 2393
Query: 1042 -------------DPP-----ANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRK 1083
+PP LT + + S +SW P+ +++ + YK DG +
Sbjct: 2394 ETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQ 2453
Query: 1084 ELIVDAEDTWIRLEGLLENTDYTVLL 1109
+ V E++ + + GL Y + L
Sbjct: 2454 VVRVGGEESEVTVGGLEPGRKYKMHL 2479
Score = 153 bits (387), Expect = 9e-37
Identities = 194/898 (21%), Positives = 328/898 (36%), Gaps = 143/898 (15%)
Query: 360 QPTALGGLQLQQRVP-----------GDWSGVTITELEPGLTYNISVYAVISN------I 402
QP QL+ RVP GD + PG Y +S++ V I
Sbjct: 984 QPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPI 1043
Query: 403 LSLPITAKVATH---LSTPQGLQFKTITETTVE---VQWEPFSFSFDGWEISFIPKNNEG 456
+ I K S P L T+T+ T + ++W FD + I + ++ +
Sbjct: 1044 IYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQP 1103
Query: 457 GVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQ------- 509
V+ V S T L PG +Y + + R P A +
Sbjct: 1104 QVVP-VEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHL 1162
Query: 510 --ILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPG 567
+ V D + + W P + D +++Y +G ++ P + V +L P
Sbjct: 1163 GNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR--DRDGRPQVVPVEGPERSFVVSSLDPD 1220
Query: 568 SRYEVSVSAVRGTNESDSATTQFTTEIDAPKN--------------LRVGSRTATSLDLE 613
+Y ++ + T TT + + L V T SL L
Sbjct: 1221 HKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLS 1280
Query: 614 WDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQ 673
W ++ + V Y G+ VP G T+ L P +Y + + + Q
Sbjct: 1281 WTVAQGPFDSFMVQYKDAQGQPQ---AVPVA-GDENEVTVPGLDPDRKYKMNLYGLRGRQ 1336
Query: 674 QSVPATMNART-------ELDSPRDL----------------MVTASSETSISLIWTKAS 710
+ P ++ A+T E SP +L VT SS S+SL WT
Sbjct: 1337 RVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQ 1396
Query: 711 GPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEY-----------------IIS 753
G D + + + G V V + T+ LEPG +Y +
Sbjct: 1397 GSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVG 1456
Query: 754 VTAERGRQQ--SLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPR 811
VTA + + + ES ++ G L + VT +SV ++W+ P D I+ Y +
Sbjct: 1457 VTAPQQEETPPATESPLEPRLG-----ELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDK 1511
Query: 812 DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPK--- 868
D + +++ V+ D +R + L+P +Y +N+ +H P+ I T PP
Sbjct: 1512 DGQPQVVPVAAD--QREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPAT 1569
Query: 869 ------------DITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVT 916
++T++++T DSV +SW+ P FD + V Y+ G+ V
Sbjct: 1570 EASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRD-GQPQVVPVAADQR 1628
Query: 917 EFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPV---------DLIATNITPT 967
E TI L P+ +Y+ L ++ + + T +L T+ TP
Sbjct: 1629 EVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPD 1688
Query: 968 EALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYAT--- 1024
L W P G+ +++V+ + + V+G + L Y +Y
Sbjct: 1689 SLRLSWTVPEGQFDSFVVQFKD-KDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGK 1747
Query: 1025 --NGPLTSGTISTNFSTLLD-----PPA-----NLTASEVTRQSALISWQPPRAEIENYV 1072
+GPLT+ + S + D PP L + VT+ S +SW P + +++V
Sbjct: 1748 KRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFV 1807
Query: 1073 LTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGR 1130
+ YK DG + + V+ + + GL Y +LL S T GR
Sbjct: 1808 VQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGR 1865
Score = 148 bits (373), Expect = 4e-35
Identities = 189/912 (20%), Positives = 346/912 (37%), Gaps = 144/912 (15%)
Query: 328 PPE--DLRVAGISDRSIELEWDGPMAVTE-YVISYQPTALGGLQLQQRVPGDWSGVTITE 384
PP +L V + S+ L W P + +VI Y+ G V G IT
Sbjct: 1062 PPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDR--DGQPQVVPVEGPQRSAVITS 1119
Query: 385 LEPGLTYNISVYAVISNILSLPITAKVAT------HLSTPQGLQFKTITETT---VEVQW 435
L+PG Y +Y + P+ A+ TP L +T+ T + + W
Sbjct: 1120 LDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSW 1179
Query: 436 EPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPP 495
FD + + + ++ V+ V SF + L P +Y + + + R P
Sbjct: 1180 TVPEGQFDTFMVQYRDRDGRPQVVP-VEGPERSFVVSSLDPDHKYRFTLFGIANKKRYGP 1238
Query: 496 TSASVSTV------------IDGPT--QILVRDVSDTVAFVEWIPPRAKVDFILLKYGLV 541
+A +T ++ P ++ V V+ + W + D +++Y
Sbjct: 1239 LTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTVAQGPFDSFMVQYK-- 1296
Query: 542 GGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRG------------------TNES 583
+G + ++ +V L P +Y++++ +RG +E+
Sbjct: 1297 DAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDET 1356
Query: 584 DSATTQFTTEIDAPKNLRVGSRTAT-----SLDLEWDNSEAEVQEYKVVYSTLAGEQYHE 638
S T T ++P+ +G T T SL L W + + V Y G
Sbjct: 1357 PSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDRDGR---- 1412
Query: 639 VLVPRGI---GPTTRATLTDLVPGTEYGVGISAVMNSQQSVPAT---MNARTELDSPR-- 690
PR + G + T+ L PG +Y + + + Q+ P + + A + ++P
Sbjct: 1413 ---PRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPAT 1469
Query: 691 ---------DLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTL 741
+L VT + S+ L WT G D + + + G V V D+ T+
Sbjct: 1470 ESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKDKDGQPQVVPVAADQREVTV 1529
Query: 742 TDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRP---------------ISHLHFSHVT 786
+LEP +Y +++ Q+ +V T P + L + +T
Sbjct: 1530 YNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDIT 1589
Query: 787 SSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVA 846
SV ++W+ P D ++ Y RD + +++ V+ D +R + L+P+ +Y L
Sbjct: 1590 PDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVVPVAAD--QREVTIPDLEPSRKYKFLLFG 1647
Query: 847 VHGTVTSEPIV--------GSITTGIDPPK--DITISNVTKDSVMVSWSPPVASFDYYRV 896
+ P+ G + G PP+ ++ +++ T DS+ +SW+ P FD + V
Sbjct: 1648 IQDGKRRSPVSVEAKTVARGDASPGA-PPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVV 1706
Query: 897 SYRPTQVGRLDSSVVPNTVTE--FTITRLNPATEYEISLNSVRGREESERIC----TLVH 950
++ VVP E T+T L+ +Y L + G++ + T
Sbjct: 1707 QFKDKD----GPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEAR 1762
Query: 951 TAMDNP-----------VDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILV 999
+AMD+ +L T +T L W P G+ +++V+ + + V
Sbjct: 1763 SAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQPQVVPV 1822
Query: 1000 DGVSEEFRLVDLLPSTHYTATMYATN-----GPLTSGTISTNF------STLLDPPA--- 1045
+G E + L P+ Y +Y + GP+++ I+ +T PPA
Sbjct: 1823 EGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEP 1882
Query: 1046 ---NLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLEN 1102
LT E T + +SW E +++ + Y DG + + + + I L GL +
Sbjct: 1883 HLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESD 1942
Query: 1103 TDYTVLLQAAQD 1114
Y V L D
Sbjct: 1943 HRYLVTLYGFSD 1954
Score = 45.8 bits (107), Expect = 3e-04
Identities = 28/104 (26%), Positives = 38/104 (36%), Gaps = 15/104 (14%)
Query: 248 GECVCEEPYTGEDCRELRCPGDCSGKGRCANGTCLCEEGYVGEDCGQR------------ 295
G C G ++R G + TC CE G+ G C
Sbjct: 123 GGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPS 182
Query: 296 ---QCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAG 336
C + C+ +G+C G CVC GY GP C + P D + G
Sbjct: 183 ASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGWPSCPGDCQGRG 226
>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
Length = 673
Score = 466 bits (1200), Expect = e-131
Identities = 248/669 (37%), Positives = 359/669 (53%), Gaps = 22/669 (3%)
Query: 704 LIWTKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS 763
L W+ A GP D + + + ++G + V D++ ++ LEP Y + ++
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRL 62
Query: 764 LESTVDAFTGFRP-----------ISHLHFSHVTSSSVNITWSDPSPPADRLILNYS--- 809
+ + TG P +S L + VT+SS+ + W P D +L +
Sbjct: 63 GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPS 122
Query: 810 -----PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITT-- 862
P E+ + T+ AVL L+ T Y + L + G ++ I G+ T
Sbjct: 123 PSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 182
Query: 863 -GIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTIT 921
++ P+D+ S + + S V+W PP + D ++VSY+ G S V +
Sbjct: 183 PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQ 242
Query: 922 RLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVE 981
L P YE+++ SVRG EESE + + T D P L A N+T A+L WK P V+
Sbjct: 243 GLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVD 302
Query: 982 NYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLL 1041
Y + +T G + ++ L DL+ T+YTAT+ GP + S F+T L
Sbjct: 303 TYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGL 362
Query: 1042 DPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLE 1101
+ P +L A EVT ++AL++W P Y+L++ + G +E+++ T +L GL
Sbjct: 363 EAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLFP 422
Query: 1102 NTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHPQDCAQHLMNGDTLSGVYPIFLNGELS 1161
+T Y LQA + ST+FTTGG P P+DC + + NG S IFLNG
Sbjct: 423 STSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTSTIFLNGNRE 482
Query: 1162 QKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVEDEFWLGLDNIHRITSQ 1221
+ L V+CDM TDGGGW+VFQRR +GQTDF+R W DY GFGN+ EFWLG + +H +T
Sbjct: 483 RPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQA 542
Query: 1222 GRYELRVDMRDGQEAAFASYDRFSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDR 1281
G Y +RVD+R G EA FA YD F V+ + Y+L + Y+GTAGDS+SYH G FS DR
Sbjct: 543 GDYSMRVDLRAGDEAVFAQYDSFHVDSAAEYYRLHLEGYHGTAGDSMSYHSGSVFSARDR 602
Query: 1282 DNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMR 1341
D + + +CA+SY+GAWWY+NCH NLNG YG + QG++WYHWKG EFS+PF EMK+R
Sbjct: 603 DPNSLLISCAVSYRGAWWYRNCHYANLNGLYGSTVDHQGVSWYHWKGFEFSVPFTEMKLR 662
Query: 1342 PYNHRLMAG 1350
P N R AG
Sbjct: 663 PRNFRSPAG 671
Score = 121 bits (304), Expect = 4e-27
Identities = 99/377 (26%), Positives = 164/377 (43%), Gaps = 25/377 (6%)
Query: 332 LRVAGISDRSIELEWDGPMAVTEYVI---------SYQPTALGGLQLQQRVPGDWSGVTI 382
L V ++ S+ L W+ P + + + +P LQ + VPG +
Sbjct: 90 LSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVL 149
Query: 383 TELEPGLTYNISVYAVIS--NILSLPITAKVATH-LSTPQGLQFKTITETTVEVQWEPFS 439
+L G Y++++Y + S+ TA+ + L +P+ LQF I ET+ +V W P
Sbjct: 150 RDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPP 209
Query: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
D +++S+ + QV + GL PG Y V VV+++ S P +
Sbjct: 210 SRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGF 269
Query: 500 VSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLS-- 557
++TV DGPTQ+ ++++ A + W PP+ VD Y + G + + P S
Sbjct: 270 LTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVD----TYDVQVTAPGAPPLQAETPGSAV 325
Query: 558 QYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNS 617
Y + L + Y +V +RG N + A+ FTT ++AP++L T + L W
Sbjct: 326 DYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEP 385
Query: 618 EAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVP 677
Y + + T G Q E+L+P GI T L L P T Y + A+ P
Sbjct: 386 PVRPAGYLLSFHT-PGGQNQEILLPGGI---TSHQLLGLFPSTSYNARLQAMWGQSLLPP 441
Query: 678 ATMNART---ELDSPRD 691
+ + T + PRD
Sbjct: 442 VSTSFTTGGLRIPFPRD 458
Score = 120 bits (301), Expect = 9e-27
Identities = 111/456 (24%), Positives = 184/456 (40%), Gaps = 30/456 (6%)
Query: 431 VEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQ 490
+ + W FD + + + N + + V D + +GL+P Y + L E
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALL-VDGDQSKILISGLEPSTPYRFLLYGLHEG 59
Query: 491 ARSPPTSASVSTVID--GPT---------QILVRDVSDTVAFVEWIPPRAKVDFILLKYG 539
R P SA +T + G T Q+ V DV+ + + W P D LL++G
Sbjct: 60 KRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFG 119
Query: 540 LVGGEGGRTTFR------LQPPLSQYS--VQALRPGSRYEVSVSAVRGTNESDS---ATT 588
+ R L P +++S ++ LR G+ Y +++ +RG +++DS
Sbjct: 120 VPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTAR 179
Query: 589 QFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPT 648
+ +++P++L+ TS + W + +KV Y G + V V G
Sbjct: 180 TLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVD---GQA 236
Query: 649 TRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTK 708
L L+PG Y V + +V ++S P T T D P L +E L W
Sbjct: 237 RTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKP 296
Query: 709 ASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTV 768
P+D Y + T + P Y L DL Y +V RG + +++
Sbjct: 297 PQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI 356
Query: 769 DAFTGFRPISHLHFSHVTSSSVNITWSDPS-PPADRLILNYSPRDEEEEMMEVSLDATKR 827
TG L VT + +TW++P PA L+ ++P + +E++ L
Sbjct: 357 TFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL---LPGGIT 413
Query: 828 HAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTG 863
L+GL P+T Y L A+ G P+ S TTG
Sbjct: 414 SHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTG 449
Score = 119 bits (298), Expect = 2e-26
Identities = 120/458 (26%), Positives = 190/458 (41%), Gaps = 38/458 (8%)
Query: 342 IELEWD---GPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAV 398
+ L W GP +V+ Y+ T G V GD S + I+ LEP Y +Y +
Sbjct: 1 MRLSWSVAQGPF--DSFVVQYEDT--NGQPQALLVDGDQSKILISGLEPSTPYRFLLYGL 56
Query: 399 ISNILSLPITAKVATHLSTPQG------------LQFKTITETTVEVQWEPFSFSFDGWE 446
P++A+ T L+ P G L +T +++ + WE +FD +
Sbjct: 57 HEGKRLGPLSAEGTTGLA-PAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFL 115
Query: 447 ISF-IPKNN----EGGVIAQ----VPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPP-- 495
+ F +P + + Q VP S L+ G Y + + L+ ++
Sbjct: 116 LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQ 175
Query: 496 -TSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQP 554
T+ ++S V++ P + ++ +T A V W+PP ++ D + Y L G G + ++
Sbjct: 176 GTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADG-GEPQSVQVDG 234
Query: 555 PLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEW 614
+Q L PG+RYEV+V +VRG ES+ T TT D P LR + T L W
Sbjct: 235 QARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHW 294
Query: 615 DNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
+ V Y V T G + P G L DLV T Y + +
Sbjct: 295 KPPQNPVDTYD-VQVTAPGAPPLQAETP---GSAVDYPLHDLVLHTNYTATVRGLRGPNL 350
Query: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPK 734
+ PA++ T L++PRDL + + L WT+ Y ++F G E+ +P
Sbjct: 351 TSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPG 410
Query: 735 DRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFT 772
TS+ L L P Y + A G Q L +FT
Sbjct: 411 GITSHQLLGLFPSTSYNARLQAMWG-QSLLPPVSTSFT 447
Score = 71.6 bits (174), Expect = 5e-12
Identities = 60/265 (22%), Positives = 108/265 (40%), Gaps = 5/265 (1%)
Query: 329 PEDLRVAGISDRSIELEW-DGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEP 387
P DL+ + I + S ++ W P + +SYQ A GG +V G + L P
Sbjct: 188 PRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQ-LADGGEPQSVQVDGQARTQKLQGLIP 246
Query: 388 GLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEI 447
G Y ++V +V S P+T + T P L+ +TE + W+P D +++
Sbjct: 247 GARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDV 306
Query: 448 SFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGP 507
+ + A+ P + L Y V L+ + P S + +T ++ P
Sbjct: 307 Q-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAP 365
Query: 508 TQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPG 567
+ ++V+ A + W P + LL + GG+ L ++ + + L P
Sbjct: 366 RDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQ--NQEILLPGGITSHQLLGLFPS 423
Query: 568 SRYEVSVSAVRGTNESDSATTQFTT 592
+ Y + A+ G + +T FTT
Sbjct: 424 TSYNARLQAMWGQSLLPPVSTSFTT 448
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 356 bits (913), Expect = 1e-97
Identities = 266/878 (30%), Positives = 413/878 (47%), Gaps = 56/878 (6%)
Query: 293 GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351
G++ +N E+ L + PD APP D V + D SI + W P A
Sbjct: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
Query: 352 VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
+T Y I Y P+ G + +P + VT+++L+PG+ YNI++YAV N S P+ +
Sbjct: 838 ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
Query: 412 AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
T + +P+ LQF +T+ V + W P + G+ + IP N G ++P
Sbjct: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
Query: 465 DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523
+F + TGL PG Y V A+ S P +A +T +D PT + + +D+ V
Sbjct: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
Query: 524 WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
W PPRA++ L GL G + + P +S+Y ++ L+P S Y VS+ A++G ES
Sbjct: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
Query: 584 DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638
AT FTT P N V T T++ + W + A +K+ V + GE E
Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
Query: 639 VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697
V G ++ L PG EY I + + Q+ P T L P +L + A+
Sbjct: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
Query: 698 SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752
+T + ++ W +++ P I YRIT TP++ G + E V D++S T +L PG EY +
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
Query: 753 SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWS-DPSPPADRLILNYSPR 811
SV + ++S+ + P + L F+++ ++ +TW+ PS ++ YSP
Sbjct: 1246 SVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
Query: 812 DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDIT 871
EE++ E+S+ + VL L P TEY+V++ +V+ S P+ G TG+D P I
Sbjct: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
Query: 872 ISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEFTITRLNPATEYE 930
S++T +S V W P A+ YR+ + P GR VP++ T+T L P TEY
Sbjct: 1366 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
Query: 931 ISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHF 990
+S+ ++ GREES + T D P DL TPT L+ W AP V Y I T+
Sbjct: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRI--TYG 1483
Query: 991 AVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATNG----PLTSGTISTNFSTLLD 1042
G + V G + L P YT T+YA G P +S IS N+ T +D
Sbjct: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
Query: 1043 PPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSRKELIVDAEDTWIRLEGLL 1100
P+ + ++V S + W P + + Y T K+ G K + T + +EGL
Sbjct: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
Query: 1101 ENTDYTVLLQAAQDTTWSS-ITSTAFTTGGRVFPHPQD 1137
+Y V + A + S + TA TT P P D
Sbjct: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTT----IPAPTD 1637
Score = 298 bits (763), Expect = 2e-80
Identities = 210/717 (29%), Positives = 336/717 (46%), Gaps = 24/717 (3%)
Query: 326 VAPPEDLRVAGISDRSI-ELEWDGPMA--VTEYVISYQPT-ALGGLQLQQRVPGDWSGVT 381
++PP +L + D + + W+ +T Y I+ PT G L++ V D S T
Sbjct: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
Query: 382 ITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SF 440
L PGL YN+SVY V + S+PI+ + + P L+F I T+ V W P S
Sbjct: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
Query: 441 SFDGWEISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSA 498
+ + + P NE V ++ PSD + T L PG EY+V+V ++ EQ S P
Sbjct: 1294 DLTNFLVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
Query: 499 SVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQ 558
T +D PT I D++ V WI PRA + +++ G R+ +
Sbjct: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
Query: 559 YSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSE 618
++ L PG+ Y VS+ A+ G ES Q +T D P++L V + T TSL + WD
Sbjct: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 619 AEVQEYKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQ 673
V+ Y++ Y G E VP G + AT++ L PG +Y + + AV +
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
Query: 674 QSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVT 731
S P ++N RTE+D P + VT + SIS+ W +S P+ YR+T TP +G T
Sbjct: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
D+T T+ L+P EY++SV A+ +S A T + L F+ VT +S++
Sbjct: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLS 1649
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
W+ P+ + +P+++ M E++L V+ GL AT+Y V++ A+ T+
Sbjct: 1650 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1709
Query: 852 TSEPIVGSITT--GIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSS 909
TS P G +TT + PP+ +++ T+ ++ +SW + ++V P
Sbjct: 1710 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1769
Query: 910 VVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969
+ V +TIT L P T+Y+I L ++ S + TA+D P +L TP
Sbjct: 1770 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSL 1829
Query: 970 LLQWKAPVGEVENYVIVLTHFAVAGETILV---DGVSEEFRLVDLLPSTHYTATMYA 1023
L+ W+ P + Y+I ++ GV+E + L P T YT + A
Sbjct: 1830 LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA-TITGLEPGTEYTIYVIA 1885
Score = 271 bits (692), Expect = 4e-72
Identities = 211/831 (25%), Positives = 361/831 (43%), Gaps = 24/831 (2%)
Query: 321 PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379
P V P DL+ ++D + + W P AVT Y + P L G Q+ +
Sbjct: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
Query: 380 VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439
+T L PG+TY V+AV S P+TA+ T L P LQF T++TV V+W P
Sbjct: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
G+ ++ V V+ + L+P EY V++VA+K SP +
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 500 VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557
+T+ G + +V++T + W P PR I K G+ +GG +
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
Query: 558 QYSVQALRPGSRYEVSVSAVRGTNESDSA-TTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615
V L PG Y ++ +R E D+ + T + P NL + + T L + W+
Sbjct: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
Query: 616 NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
S ++ Y++ + G+Q + L + T +L PG EY V + V + ++
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWTKA-SGPIDHYRITFTP--SSGIASEVT 731
SVP + + P DL T ++ + W S + ++ + ++P + +E++
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
+ + LT+L PG EY++SV++ + +S TG + + FS +T++S
Sbjct: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
+ W P + + P E + ++ L L P TEY+V++VA++G
Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
Query: 852 TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGR-LDSSV 910
S ++G +T D P+D+ + T S+++SW P + YYR++Y T +
Sbjct: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1495
Query: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREE----SERICTLVHTAMDNPVDLIATNITP 966
VP + + TI+ L P +Y I++ +V GR + S+ I T +D P + T++
Sbjct: 1496 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1555
Query: 967 TEALLQWKAPVGEVENYVIVLTHFAVAG--ETILVDGVSEEFRLVDLLPSTHYTATMYAT 1024
++W V Y + T G +T E + L P+ Y ++YA
Sbjct: 1556 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1615
Query: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSR 1082
N S + T + P +L ++VT S W PP ++ Y +T K G
Sbjct: 1616 NPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
Query: 1083 KELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
KE+ + + + + + GL+ T Y V + A +DT S TT V P
Sbjct: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
Score = 267 bits (683), Expect = 4e-71
Identities = 212/802 (26%), Positives = 360/802 (44%), Gaps = 35/802 (4%)
Query: 337 ISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVY 396
+++ +I + W P + + +P+ G + + V D + ++ L PG+ Y ++
Sbjct: 1098 VTETTIVITWT-PAPRIGFKLGVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
Query: 397 AVISNI-LSLPITAKVATHLSTPQGLQFKTITETTV-EVQWEPFSF-SFDGWEISFIPKN 453
+ PI KV T LS P L + +T V V WE + G+ I+ P N
Sbjct: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
Query: 454 NEGGVIAQ--VPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQIL 511
+ G + V +D +S L PG EY V+V +K+ S P S ++ + PT +
Sbjct: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLR 1274
Query: 512 VRDVSDTVAFVEWIPPRAKVDF--ILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSR 569
++ V W PP + +D L++Y V E + P + + L PG+
Sbjct: 1275 FTNIGPDTMRVTWAPPPS-IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
Query: 570 YEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYS 629
Y VSVS+V +ES + T +D+P + TA S + W A + Y++ +
Sbjct: 1334 YVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH 1393
Query: 630 T--LAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELD 687
+G E VP TLT+L PGTEY V I A+ ++S T D
Sbjct: 1394 PEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD 1449
Query: 688 SPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVTVPKDRTSYTLTDLE 745
PRDL V A++ TS+ + W + + +YRIT+ + G + E TVP +++ T++ L+
Sbjct: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
Query: 746 PGAEYIISVTAERGRQQSLESTVDAFTGFRPI----SHLHFSHVTSSSVNITWSDPSPPA 801
PG +Y I+V A GR S S+ +R S + + V +S+++ W S P
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
Query: 802 DRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSIT 861
+ +P++ + + + GLQP EY+V++ A + + S+P+V +
Sbjct: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629
Query: 862 TGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTVTEFTI 920
T I P D+ + VT S+ W+PP YRV P + G + + + +
Sbjct: 1630 TTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1689
Query: 921 TRLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPTEALLQWKAPV 977
+ L AT+YE+S+ +++ S R V T ++N P T+ T T + W+
Sbjct: 1690 SGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1748
Query: 978 GEVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYATNGPLTSGTIS 1034
+ + + G+T + + + R + L P T Y +Y N S +
Sbjct: 1749 ETITGFQVDAV--PANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1806
Query: 1035 TNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAED--T 1092
+ ST +D P+NL T S L+SWQPPRA I Y++ Y+ +E++ T
Sbjct: 1807 IDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVT 1866
Query: 1093 WIRLEGLLENTDYTVLLQAAQD 1114
+ GL T+YT+ + A ++
Sbjct: 1867 EATITGLEPGTEYTIYVIALKN 1888
Score = 245 bits (626), Expect = 2e-64
Identities = 215/816 (26%), Positives = 355/816 (43%), Gaps = 61/816 (7%)
Query: 344 LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391
++W+ P +++Y++ ++P G + +PG + TI L+PG+ Y
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 392 ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442
++ + + S P+T+ T +TP T IT ++ V W S +
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 443 DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500
G+ + + + + + +PS TS N L PG +YIVNV + E +S S S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
+T D P V V DT V W P+A + + Y EG T L + +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
Query: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613
+ L+PG +Y +++ AV ES Q T + +P++L+ T + +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 614 WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
W E+ V Y+ V+ L GE + + R T A +T L PG Y + AV +
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
Query: 672 SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730
++S P T T+LD+P +L +++++ + WT I YR+T G +
Sbjct: 983 GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788
V + Y L +L+P +EY +S+ A +G Q+S ++T FT +P S + + + VT +
Sbjct: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
Query: 789 SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845
++ ITW+ PA R+ L P E EV+ D+ V+ GL P EY+ + V
Sbjct: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
Query: 846 AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901
G PIV + T + PP ++ + +N + VSW YR++ PT
Sbjct: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
Query: 902 QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961
Q G VV + T L+P EY +S+ +V+ +ES I + A+ P DL
Sbjct: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
Query: 962 TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE----TILVDGVSEEFRLVDLLPSTHY 1017
TNI P + W AP ++ ++ + V E + + L +LLP T Y
Sbjct: 1276 TNIGPDTMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1334
Query: 1018 TATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY-- 1075
++ + S + T LD P + S++T S + W PRA I Y + +
Sbjct: 1335 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1394
Query: 1076 KSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111
+ G +E V I L L T+Y V + A
Sbjct: 1395 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
Score = 245 bits (626), Expect = 2e-64
Identities = 220/851 (25%), Positives = 350/851 (41%), Gaps = 56/851 (6%)
Query: 325 AVAPPEDLRVAGISDRSIELEWDGPMAV--TEYVISYQPTALGGLQLQQRVPGDWSGVTI 382
AV PP DLR I ++ + W P ++ T +++ Y P + + + V +
Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
Query: 383 TELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSF 442
T L PG Y +SV +V S P+ + T L +P G+ F IT + V W +
Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI 1385
Query: 443 DGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVS 501
G+ I P++ G +VP S T L PG EY+V++VAL + SP S
Sbjct: 1386 TGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
Query: 502 TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSV 561
TV D P + V + T + W P V + + YG GG F + S ++
Sbjct: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
Query: 562 QALRPGSRYEVSVSAVRGTNESDSATT----QFTTEIDAPKNLRVGSRTATSLDLEWDNS 617
L+PG Y ++V AV G +S +++ + TEID P ++V S+ ++W S
Sbjct: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
Query: 618 EAEVQEYKVVYSTLAGEQYHEVLVPRGIGPT-TRATLTDLVPGTEYGVGISAVMNSQQSV 676
+ V Y+V + G + + GP T T+ L P EY V + A S +S
Sbjct: 1566 SSPVTGYRVTTTPKNGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
Query: 677 PATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPK 734
P A T + +P DL T + TS+S WT + + YR+ TP +G E+ +
Sbjct: 1623 PLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1682
Query: 735 DRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSSSVNI 792
D +S ++ L +Y +SV A + S + V P + T +++ I
Sbjct: 1683 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1742
Query: 793 TWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVT 852
+W + ++ P + + + ++ R + GLQP T+Y + L ++
Sbjct: 1743 SWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1801
Query: 853 SEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVP 912
S P+V +T ID P ++ T +S++VSW PP A Y + Y + G VVP
Sbjct: 1802 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPREVVP 1859
Query: 913 NT---VTEFTITRLNPATEYEISLNSVRGREESE------------RICTLVHTAMDNPV 957
VTE TIT L P TEY I + +++ ++SE ++ TL H + P
Sbjct: 1860 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 1919
Query: 958 DLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHY 1017
L ++ T + G I L + ++ + EE P T
Sbjct: 1920 IL---DVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTA 1976
Query: 1018 TATMYATN--GPLTSGTISTNFSTLLD---------PPANLTASEVTRQSAL----ISWQ 1062
T + P I D P N AS T Q AL ISW
Sbjct: 1977 TPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNAS--TGQEALSQTTISWA 2034
Query: 1063 PPRAEIENYVLTYK--STDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSI 1120
P + + Y+++ TD + V T L GL Y ++++A +D +
Sbjct: 2035 PFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKV 2093
Query: 1121 TSTAFTTGGRV 1131
T G V
Sbjct: 2094 REEVVTVGNSV 2104
Score = 194 bits (492), Expect = 6e-49
Identities = 142/551 (25%), Positives = 247/551 (44%), Gaps = 15/551 (2%)
Query: 319 QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377
+G + + P + + I+ S + W P A +T Y I + P G + RVP
Sbjct: 1351 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
Query: 378 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
+ +T+T L PG Y +S+ A+ S + + +T P+ L+ T T++ + W+
Sbjct: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
Query: 438 FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
+ + + I++ V VP ++ +GLKPG +Y + V A+ + SP +
Sbjct: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
Query: 497 SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
S +S T ID P+Q+ V DV D V+W+P + V + G G T
Sbjct: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
Query: 553 QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
P ++ +++ L+P Y VSV A + ES T I AP +L+ T TSL
Sbjct: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSA 1650
Query: 613 EWDNSEAEVQEYKVVYSTL--AGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM 670
+W ++ Y+V + G L P ++ ++ L+ T+Y V + A+
Sbjct: 1651 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP----DSSSVVVSGLMVATKYEVSVYALK 1706
Query: 671 NSQQSVPA--TMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIAS 728
++ S PA + + PR VT ++ET+I++ W + I +++ P++G
Sbjct: 1707 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTP 1766
Query: 729 -EVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTS 787
+ T+ D SYT+T L+PG +Y I + +S +DA T S+L F T
Sbjct: 1767 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTP 1826
Query: 788 SSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAV 847
+S+ ++W P I+ Y + A + GL+P TEY + ++A+
Sbjct: 1827 NSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1886
Query: 848 HGTVTSEPIVG 858
SEP++G
Sbjct: 1887 KNNQKSEPLIG 1897
Score = 134 bits (338), Expect = 5e-31
Identities = 121/467 (25%), Positives = 191/467 (40%), Gaps = 35/467 (7%)
Query: 695 TASSETSISLIWTKAS-GPIDHYRITFTPSSGIA--SEVTVPKDRTSYTLTDLEPGAEY- 750
T S S + W I Y + + P + + E T+P SYT+ L+PG Y
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYE 678
Query: 751 --IISVTAERGRQQ-----------SLESTVDAFTG----FRPI--SHLHFSHVTSSSVN 791
+IS+ + G Q+ S T + TG F P+ + + +T+SS
Sbjct: 679 GQLISIQ-QYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
++W S + Y +E +E + L +T + L P +YIVN+ +
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
Query: 852 TSEPIVG-SITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSV 910
I+ S TT D P D T+ V S++V WS P A YR+ Y P+ G
Sbjct: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
Query: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHT-------AMDNPVDLIATN 963
+P T T++ L P +Y I++ +V +ES + T + +P DL
Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
Query: 964 ITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEE--FRLVDLLPSTHYTATM 1021
+T + + W P V Y + + + GE +S + L P Y +
Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
Query: 1022 YATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKST-DG 1080
+A + S ++ +T LD P NL T + L+ W PPRA+I Y LT T G
Sbjct: 978 FAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRG 1037
Query: 1081 SRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTT 1127
++ V + L L ++YTV L A + S + FTT
Sbjct: 1038 QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 356 bits (913), Expect = 1e-97
Identities = 266/878 (30%), Positives = 413/878 (47%), Gaps = 56/878 (6%)
Query: 293 GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351
G++ +N E+ L + PD APP D V + D SI + W P A
Sbjct: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
Query: 352 VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
+T Y I Y P+ G + +P + VT+++L+PG+ YNI++YAV N S P+ +
Sbjct: 838 ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
Query: 412 AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
T + +P+ LQF +T+ V + W P + G+ + IP N G ++P
Sbjct: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
Query: 465 DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523
+F + TGL PG Y V A+ S P +A +T +D PT + + +D+ V
Sbjct: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
Query: 524 WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
W PPRA++ L GL G + + P +S+Y ++ L+P S Y VS+ A++G ES
Sbjct: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
Query: 584 DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638
AT FTT P N V T T++ + W + A +K+ V + GE E
Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
Query: 639 VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697
V G ++ L PG EY I + + Q+ P T L P +L + A+
Sbjct: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
Query: 698 SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752
+T + ++ W +++ P I YRIT TP++ G + E V D++S T +L PG EY +
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
Query: 753 SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWS-DPSPPADRLILNYSPR 811
SV + ++S+ + P + L F+++ ++ +TW+ PS ++ YSP
Sbjct: 1246 SVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
Query: 812 DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDIT 871
EE++ E+S+ + VL L P TEY+V++ +V+ S P+ G TG+D P I
Sbjct: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
Query: 872 ISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEFTITRLNPATEYE 930
S++T +S V W P A+ YR+ + P GR VP++ T+T L P TEY
Sbjct: 1366 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
Query: 931 ISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHF 990
+S+ ++ GREES + T D P DL TPT L+ W AP V Y I T+
Sbjct: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRI--TYG 1483
Query: 991 AVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATNG----PLTSGTISTNFSTLLD 1042
G + V G + L P YT T+YA G P +S IS N+ T +D
Sbjct: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
Query: 1043 PPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSRKELIVDAEDTWIRLEGLL 1100
P+ + ++V S + W P + + Y T K+ G K + T + +EGL
Sbjct: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
Query: 1101 ENTDYTVLLQAAQDTTWSS-ITSTAFTTGGRVFPHPQD 1137
+Y V + A + S + TA TT P P D
Sbjct: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTT----IPAPTD 1637
Score = 310 bits (794), Expect = 6e-84
Identities = 232/827 (28%), Positives = 372/827 (44%), Gaps = 37/827 (4%)
Query: 326 VAPPEDLRVAGISDRSI-ELEWDGPMA--VTEYVISYQPT-ALGGLQLQQRVPGDWSGVT 381
++PP +L + D + + W+ +T Y I+ PT G L++ V D S T
Sbjct: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
Query: 382 ITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SF 440
L PGL YN+SVY V + S+PI+ + + P L+F I T+ V W P S
Sbjct: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
Query: 441 SFDGWEISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSA 498
+ + + P NE V ++ PSD + T L PG EY+V+V ++ EQ S P
Sbjct: 1294 DLTNFLVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
Query: 499 SVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQ 558
T +D PT I D++ V WI PRA + +++ G R+ +
Sbjct: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
Query: 559 YSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSE 618
++ L PG+ Y VS+ A+ G ES Q +T D P++L V + T TSL + WD
Sbjct: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 619 AEVQEYKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQ 673
V+ Y++ Y G E VP G + AT++ L PG +Y + + AV +
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
Query: 674 QSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVT 731
S P ++N RTE+D P + VT + SIS+ W +S P+ YR+T TP +G T
Sbjct: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
D+T T+ L+P EY++SV A+ +S A T + L F+ VT +S++
Sbjct: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLS 1649
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
W+ P+ + +P+++ M E++L V+ GL AT+Y V++ A+ T+
Sbjct: 1650 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1709
Query: 852 TSEPIVGSITT--GIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSS 909
TS P G +TT + PP+ +++ T+ ++ +SW + ++V P
Sbjct: 1710 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1769
Query: 910 VVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969
+ V +TIT L P T+Y+I L ++ S + TA+D P +L TP
Sbjct: 1770 TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSL 1829
Query: 970 LLQWKAPVGEVENYVIVLTHFAVAGETILV---DGVSEEFRLVDLLPSTHYTATMYATNG 1026
L+ W+ P + Y+I ++ GV+E + L P T YT + A
Sbjct: 1830 LVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA-TITGLEPGTEYTIYVIALKN 1888
Query: 1027 PLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYK--STDGSRKE 1084
S + T E Q+ ISW P + + Y+++ TD +
Sbjct: 1889 NQKSEPLIGR---------KKTGQEALSQTT-ISWAPFQ-DTSEYIISCHPVGTDEEPLQ 1937
Query: 1085 LIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRV 1131
V T L GL Y ++++A +D + T G V
Sbjct: 1938 FRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 1984
Score = 271 bits (692), Expect = 4e-72
Identities = 211/831 (25%), Positives = 361/831 (43%), Gaps = 24/831 (2%)
Query: 321 PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379
P V P DL+ ++D + + W P AVT Y + P L G Q+ +
Sbjct: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
Query: 380 VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439
+T L PG+TY V+AV S P+TA+ T L P LQF T++TV V+W P
Sbjct: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
G+ ++ V V+ + L+P EY V++VA+K SP +
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 500 VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557
+T+ G + +V++T + W P PR I K G+ +GG +
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
Query: 558 QYSVQALRPGSRYEVSVSAVRGTNESDSA-TTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615
V L PG Y ++ +R E D+ + T + P NL + + T L + W+
Sbjct: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
Query: 616 NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
S ++ Y++ + G+Q + L + T +L PG EY V + V + ++
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWTKA-SGPIDHYRITFTP--SSGIASEVT 731
SVP + + P DL T ++ + W S + ++ + ++P + +E++
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
+ + LT+L PG EY++SV++ + +S TG + + FS +T++S
Sbjct: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
+ W P + + P E + ++ L L P TEY+V++VA++G
Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
Query: 852 TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGR-LDSSV 910
S ++G +T D P+D+ + T S+++SW P + YYR++Y T +
Sbjct: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1495
Query: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREE----SERICTLVHTAMDNPVDLIATNITP 966
VP + + TI+ L P +Y I++ +V GR + S+ I T +D P + T++
Sbjct: 1496 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1555
Query: 967 TEALLQWKAPVGEVENYVIVLTHFAVAG--ETILVDGVSEEFRLVDLLPSTHYTATMYAT 1024
++W V Y + T G +T E + L P+ Y ++YA
Sbjct: 1556 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1615
Query: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSR 1082
N S + T + P +L ++VT S W PP ++ Y +T K G
Sbjct: 1616 NPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
Query: 1083 KELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
KE+ + + + + + GL+ T Y V + A +DT S TT V P
Sbjct: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1726
Score = 245 bits (626), Expect = 2e-64
Identities = 215/816 (26%), Positives = 355/816 (43%), Gaps = 61/816 (7%)
Query: 344 LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391
++W+ P +++Y++ ++P G + +PG + TI L+PG+ Y
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 392 ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442
++ + + S P+T+ T +TP T IT ++ V W S +
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 443 DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500
G+ + + + + + +PS TS N L PG +YIVNV + E +S S S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
+T D P V V DT V W P+A + + Y EG T L + +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
Query: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613
+ L+PG +Y +++ AV ES Q T + +P++L+ T + +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 614 WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
W E+ V Y+ V+ L GE + + R T A +T L PG Y + AV +
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
Query: 672 SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730
++S P T T+LD+P +L +++++ + WT I YR+T G +
Sbjct: 983 GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788
V + Y L +L+P +EY +S+ A +G Q+S ++T FT +P S + + + VT +
Sbjct: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
Query: 789 SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845
++ ITW+ PA R+ L P E EV+ D+ V+ GL P EY+ + V
Sbjct: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
Query: 846 AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901
G PIV + T + PP ++ + +N + VSW YR++ PT
Sbjct: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
Query: 902 QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961
Q G VV + T L+P EY +S+ +V+ +ES I + A+ P DL
Sbjct: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
Query: 962 TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE----TILVDGVSEEFRLVDLLPSTHY 1017
TNI P + W AP ++ ++ + V E + + L +LLP T Y
Sbjct: 1276 TNIGPDTMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1334
Query: 1018 TATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY-- 1075
++ + S + T LD P + S++T S + W PRA I Y + +
Sbjct: 1335 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1394
Query: 1076 KSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111
+ G +E V I L L T+Y V + A
Sbjct: 1395 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
Score = 139 bits (349), Expect = 2e-32
Identities = 89/354 (25%), Positives = 161/354 (45%), Gaps = 16/354 (4%)
Query: 324 SAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSGVTI 382
+ + P DL+ ++ S+ +W P + +T Y + P G + + D S V +
Sbjct: 1630 TTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1689
Query: 383 TELEPGLTYNISVYAVISNILSLPITAKVAT--HLSTPQGLQFKTITETTVEVQWEPFSF 440
+ L Y +SVYA+ + S P V T ++S P+ + TETT+ + W +
Sbjct: 1690 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE 1749
Query: 441 SFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASV 500
+ G+++ +P N + + + DV S+ TGL+PG +Y + + L + ARS P
Sbjct: 1750 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1809
Query: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
ST ID P+ + + V W PPRA++ ++KY G R +P +++ +
Sbjct: 1810 STAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 1869
Query: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAE 620
+ L PG+ Y + V A++ +S+ + T G + + W + +
Sbjct: 1870 ITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT----------GQEALSQTTISWAPFQ-D 1918
Query: 621 VQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
EY + + ++ E L R G +T ATLT L G Y + + A+ + Q+
Sbjct: 1919 TSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 1970
Score = 134 bits (338), Expect = 5e-31
Identities = 121/467 (25%), Positives = 191/467 (40%), Gaps = 35/467 (7%)
Query: 695 TASSETSISLIWTKAS-GPIDHYRITFTPSSGIA--SEVTVPKDRTSYTLTDLEPGAEY- 750
T S S + W I Y + + P + + E T+P SYT+ L+PG Y
Sbjct: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYE 678
Query: 751 --IISVTAERGRQQ-----------SLESTVDAFTG----FRPI--SHLHFSHVTSSSVN 791
+IS+ + G Q+ S T + TG F P+ + + +T+SS
Sbjct: 679 GQLISIQ-QYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
++W S + Y +E +E + L +T + L P +YIVN+ +
Sbjct: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
Query: 852 TSEPIVG-SITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSV 910
I+ S TT D P D T+ V S++V WS P A YR+ Y P+ G
Sbjct: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
Query: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHT-------AMDNPVDLIATN 963
+P T T++ L P +Y I++ +V +ES + T + +P DL
Sbjct: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
Query: 964 ITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEE--FRLVDLLPSTHYTATM 1021
+T + + W P V Y + + + GE +S + L P Y +
Sbjct: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
Query: 1022 YATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKST-DG 1080
+A + S ++ +T LD P NL T + L+ W PPRA+I Y LT T G
Sbjct: 978 FAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRG 1037
Query: 1081 SRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTT 1127
++ V + L L ++YTV L A + S + FTT
Sbjct: 1038 QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 353 bits (906), Expect = 6e-97
Identities = 262/867 (30%), Positives = 409/867 (47%), Gaps = 52/867 (5%)
Query: 293 GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351
G++ +N E+ L + PD APP D V + D SI + W P A
Sbjct: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
Query: 352 VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
+T Y I Y P+ G + +P + VT+++L+PG+ YNI++YAV N S P+ +
Sbjct: 838 ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
Query: 412 AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
T + +P+ LQF +T+ V + W P + G+ + IP N G ++P
Sbjct: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
Query: 465 DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523
+F + TGL PG Y V A+ S P +A +T +D PT + + +D+ V
Sbjct: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
Query: 524 WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
W PPRA++ L GL G + + P +S+Y ++ L+P S Y VS+ A++G ES
Sbjct: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
Query: 584 DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638
AT FTT P N V T T++ + W + A +K+ V + GE E
Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
Query: 639 VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697
V G ++ L PG EY I + + Q+ P T L P +L + A+
Sbjct: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
Query: 698 SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752
+T + ++ W +++ P I YRIT TP++ G + E V D++S T +L PG EY +
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
Query: 753 SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWS-DPSPPADRLILNYSPR 811
SV + ++S+ + P + L F+++ ++ +TW+ PS ++ YSP
Sbjct: 1246 SVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
Query: 812 DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDIT 871
EE++ E+S+ + VL L P TEY+V++ +V+ S P+ G TG+D P I
Sbjct: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
Query: 872 ISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEFTITRLNPATEYE 930
S++T +S V W P A+ YR+ + P GR VP++ T+T L P TEY
Sbjct: 1366 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
Query: 931 ISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHF 990
+S+ ++ GREES + T D P DL TPT L+ W AP V Y I T+
Sbjct: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRI--TYG 1483
Query: 991 AVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATNG----PLTSGTISTNFSTLLD 1042
G + V G + L P YT T+YA G P +S IS N+ T +D
Sbjct: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
Query: 1043 PPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSRKELIVDAEDTWIRLEGLL 1100
P+ + ++V S + W P + + Y T K+ G K + T + +EGL
Sbjct: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
Query: 1101 ENTDYTVLLQAAQDTTWSS-ITSTAFT 1126
+Y V + A + S + TA T
Sbjct: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVT 1630
Score = 335 bits (860), Expect = 1e-91
Identities = 238/812 (29%), Positives = 379/812 (46%), Gaps = 30/812 (3%)
Query: 326 VAPPEDLRVAGISDRSI-ELEWDGPMA--VTEYVISYQPT-ALGGLQLQQRVPGDWSGVT 381
++PP +L + D + + W+ +T Y I+ PT G L++ V D S T
Sbjct: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
Query: 382 ITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SF 440
L PGL YN+SVY V + S+PI+ + + P L+F I T+ V W P S
Sbjct: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
Query: 441 SFDGWEISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSA 498
+ + + P NE V ++ PSD + T L PG EY+V+V ++ EQ S P
Sbjct: 1294 DLTNFLVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
Query: 499 SVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQ 558
T +D PT I D++ V WI PRA + +++ G R+ +
Sbjct: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
Query: 559 YSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSE 618
++ L PG+ Y VS+ A+ G ES Q +T D P++L V + T TSL + WD
Sbjct: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 619 AEVQEYKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQ 673
V+ Y++ Y G E VP G + AT++ L PG +Y + + AV +
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
Query: 674 QSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVT 731
S P ++N RTE+D P + VT + SIS+ W +S P+ YR+T TP +G T
Sbjct: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
D+T T+ L+P EY++SV A+ +S A T L F+ V S+
Sbjct: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1649
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
I W P R + YS ++ + + D + A L GL+P +EY V++VA+H +
Sbjct: 1650 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1709
Query: 852 TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSV 910
S+P++G+ +T I P D+ + VT S+ W+PP YRV P + G +
Sbjct: 1710 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1769
Query: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPT 967
+ + ++ L AT+YE+S+ +++ S R V T ++N P T+ T T
Sbjct: 1770 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATET 1828
Query: 968 EALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYAT 1024
+ W+ + + + G+T + + + R + L P T Y +Y
Sbjct: 1829 TITISWRTKTETITGFQV--DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1886
Query: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKE 1084
N S + + ST +D P+NL T S L+SWQPPRA I Y++ Y+ +E
Sbjct: 1887 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1946
Query: 1085 LIVDAED--TWIRLEGLLENTDYTVLLQAAQD 1114
++ T + GL T+YT+ + A ++
Sbjct: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
Score = 274 bits (700), Expect = 5e-73
Identities = 208/812 (25%), Positives = 357/812 (43%), Gaps = 24/812 (2%)
Query: 321 PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379
P V P DL+ ++D + + W P AVT Y + P L G Q+ +
Sbjct: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
Query: 380 VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439
+T L PG+TY V+AV S P+TA+ T L P LQF T++TV V+W P
Sbjct: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
G+ ++ V V+ + L+P EY V++VA+K SP +
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 500 VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557
+T+ G + +V++T + W P PR I K G+ +GG +
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
Query: 558 QYSVQALRPGSRYEVSVSAVRGTNESDS-ATTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615
V L PG Y ++ +R E D+ + T + P NL + + T L + W+
Sbjct: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
Query: 616 NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
S ++ Y++ + G+Q + L + T +L PG EY V + V + ++
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWT-KASGPIDHYRITFTP--SSGIASEVT 731
SVP + + P DL T ++ + W S + ++ + ++P + +E++
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
+ + LT+L PG EY++SV++ + +S TG + + FS +T++S
Sbjct: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
+ W P + + P E + ++ L L P TEY+V++VA++G
Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
Query: 852 TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGR-LDSSV 910
S ++G +T D P+D+ + T S+++SW P + YYR++Y T +
Sbjct: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1495
Query: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREE----SERICTLVHTAMDNPVDLIATNITP 966
VP + + TI+ L P +Y I++ +V GR + S+ I T +D P + T++
Sbjct: 1496 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1555
Query: 967 TEALLQWKAPVGEVENYVIVLTHFAVAG--ETILVDGVSEEFRLVDLLPSTHYTATMYAT 1024
++W V Y + T G +T E + L P+ Y ++YA
Sbjct: 1556 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1615
Query: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKE 1084
N S + T +D P L ++V S I+W+ P+ ++ Y +TY S + E
Sbjct: 1616 NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
Query: 1085 LI--VDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
L D E+ L+GL ++YTV + A D
Sbjct: 1676 LFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707
Score = 254 bits (650), Expect = 3e-67
Identities = 219/824 (26%), Positives = 351/824 (42%), Gaps = 26/824 (3%)
Query: 329 PEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEP 387
P +L+ +D ++ + W P A +T Y ++ T G + Q V S + L+P
Sbjct: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQP 1058
Query: 388 GLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKT-ITETTVEVQWEPFSFSFDGWE 446
Y +S+ A+ N S T T + T +TETT+ + W P G++
Sbjct: 1059 ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFK 1116
Query: 447 ISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKE-QARSPPTSASVSTVID 505
+ P G +V SD S +GL PG EY+ + L++ Q R P V T +
Sbjct: 1117 LGVRPSQG-GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLS 1175
Query: 506 GPTQILVRDVSDT-VAFVEWIPPRAK--VDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562
PT + + DT V V W + + G +G + S +
Sbjct: 1176 PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
Query: 563 ALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEA-EV 621
L PG Y VSV V+ ES + + P +LR + ++ + W + ++
Sbjct: 1236 NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDL 1295
Query: 622 QEYKVVYSTLAGEQYHEVLVPRGIGPTTRAT-LTDLVPGTEYGVGISAVMNSQQSVPATM 680
+ V YS + E E + I P+ A LT+L+PGTEY V +S+V +S P
Sbjct: 1296 TNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
Query: 681 NARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTS 738
+T LDSP + + + S ++ W I YRI P SG E VP R S
Sbjct: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
Query: 739 YTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPS 798
TLT+L PG EY++S+ A GR++S T L T +S+ I+W P+
Sbjct: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 799 PPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT----VTSE 854
+ Y + E ++ +K A + GL+P +Y + + AV G +S+
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
Query: 855 PIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPN 913
PI + T ID P + +++V +S+ V W P + YRV+ P G +
Sbjct: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1592
Query: 914 TVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQW 973
TE TI L P EY +S+ + ES+ + T +D P L T++ + W
Sbjct: 1593 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAW 1652
Query: 974 KAPVGEVENYVIVLTHFAVAGETILV--DGVSEEFRLVDLLPSTHYTATMYATNGPLTSG 1031
++P G+V Y + + + DG + L L P + YT ++ A + + S
Sbjct: 1653 ESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQ 1712
Query: 1032 TISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVL--TYKSTDGSRKELIVDA 1089
+ ST + P +L ++VT S W PP ++ Y + T K G KE+ +
Sbjct: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
Query: 1090 EDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
+ + + + GL+ T Y V + A +DT S TT V P
Sbjct: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
Score = 245 bits (626), Expect = 2e-64
Identities = 215/816 (26%), Positives = 355/816 (43%), Gaps = 61/816 (7%)
Query: 344 LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391
++W+ P +++Y++ ++P G + +PG + TI L+PG+ Y
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 392 ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442
++ + + S P+T+ T +TP T IT ++ V W S +
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 443 DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500
G+ + + + + + +PS TS N L PG +YIVNV + E +S S S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
+T D P V V DT V W P+A + + Y EG T L + +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
Query: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613
+ L+PG +Y +++ AV ES Q T + +P++L+ T + +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 614 WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
W E+ V Y+ V+ L GE + + R T A +T L PG Y + AV +
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
Query: 672 SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730
++S P T T+LD+P +L +++++ + WT I YR+T G +
Sbjct: 983 GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788
V + Y L +L+P +EY +S+ A +G Q+S ++T FT +P S + + + VT +
Sbjct: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
Query: 789 SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845
++ ITW+ PA R+ L P E EV+ D+ V+ GL P EY+ + V
Sbjct: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
Query: 846 AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901
G PIV + T + PP ++ + +N + VSW YR++ PT
Sbjct: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
Query: 902 QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961
Q G VV + T L+P EY +S+ +V+ +ES I + A+ P DL
Sbjct: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
Query: 962 TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE----TILVDGVSEEFRLVDLLPSTHY 1017
TNI P + W AP ++ ++ + V E + + L +LLP T Y
Sbjct: 1276 TNIGPDTMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1334
Query: 1018 TATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY-- 1075
++ + S + T LD P + S++T S + W PRA I Y + +
Sbjct: 1335 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1394
Query: 1076 KSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111
+ G +E V I L L T+Y V + A
Sbjct: 1395 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
Score = 245 bits (625), Expect = 2e-64
Identities = 212/830 (25%), Positives = 350/830 (42%), Gaps = 34/830 (4%)
Query: 319 QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377
+G + + P + + I+ S + W P A +T Y I + P G + RVP
Sbjct: 1351 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
Query: 378 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
+ +T+T L PG Y +S+ A+ S + + +T P+ L+ T T++ + W+
Sbjct: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
Query: 438 FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
+ + + I++ V VP ++ +GLKPG +Y + V A+ + SP +
Sbjct: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
Query: 497 SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
S +S T ID P+Q+ V DV D V+W+P + V + G G T
Sbjct: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
Query: 553 QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
P ++ +++ L+P Y VSV A + ES T ID PK L S+ +
Sbjct: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1650
Query: 613 EWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNS 672
W++ + +V Y+V YS+ + HE L P G A L L PG+EY V + A+ +
Sbjct: 1651 AWESPQGQVSRYRVTYSS-PEDGIHE-LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD 1708
Query: 673 QQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEV 730
+S P T + +P DL T + TS+S WT + + YR+ TP +G E+
Sbjct: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1768
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSS 788
+ D +S ++ L +Y +SV A + S + V P + T +
Sbjct: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1828
Query: 789 SVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVH 848
++ I+W + ++ P + + + ++ R + GLQP T+Y + L ++
Sbjct: 1829 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
Query: 849 GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDS 908
S P+V +T ID P ++ T +S++VSW PP A Y + Y + G
Sbjct: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPR 1945
Query: 909 SVVPNT---VTEFTITRLNPATEYEISLNSVRGREESERICTLVHT-AMDNPVDLIATNI 964
VVP VTE TIT L P TEY I + +++ ++SE + T + V L N+
Sbjct: 1946 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNL 2005
Query: 965 TPTEALLQWKAPVGEVENYVIVLTHFAV-AGETILVDGVSEEFRLVDLLPSTHYTATMYA 1023
E L V +TH G I + G S + V + +
Sbjct: 2006 HGPEIL-----DVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVG--QQMIFEEHGFR 2058
Query: 1024 TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYK--STDGS 1081
P T+ T + P A T ISW P + + Y+++ TD
Sbjct: 2059 RTTPPTTATPIRHRPRPYPPNVGQEALSQT----TISWAPFQ-DTSEYIISCHPVGTDEE 2113
Query: 1082 RKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRV 1131
+ V T L GL Y ++++A +D + T G V
Sbjct: 2114 PLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2163
Score = 166 bits (421), Expect = 1e-40
Identities = 159/647 (24%), Positives = 273/647 (42%), Gaps = 42/647 (6%)
Query: 506 GPTQILVRDVSDTVAF--VEWIPPR-AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562
GP ++ + + ++W P+ + + +L++ G + L+ Y+++
Sbjct: 610 GPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIK 669
Query: 563 ALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPKNLRVGSRTATSLDLEWDNSEA 619
L+PG YE + +++ + FTT N G T S + S
Sbjct: 670 GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
Query: 620 EVQEYKVVYS------TLAGEQYHEVLVPRGIGP--------TTRATLTDLVPGTEYGVG 665
E+ V S T++G + L G P T + DL+PG +Y V
Sbjct: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
Query: 666 ISAVM-NSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS- 723
+ + + +QS+ + + T D+P D V +TSI + W++ PI YRI ++PS
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
Query: 724 SGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISH---- 779
G ++E+ +P+ S TL+DL+PG +Y I++ A Q+S + T P S
Sbjct: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
Query: 780 ---LHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQP 836
L F VT V I W+ P ++ P + E + + A + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 837 ATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896
Y + AV S+P+ TT +D P ++ N T +V+V W+PP A YR+
Sbjct: 970 GVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRL 1029
Query: 897 SYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMD-- 954
+ T+ G+ V +V+++ + L PA+EY +SL +++G +ES + T V T +
Sbjct: 1030 TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK-ATGVFTTLQPG 1088
Query: 955 NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETIL-VDGVSEEFRLVDLLP 1013
+ + T +T T ++ W P + + V + GE V S + L P
Sbjct: 1089 SSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRP--SQGGEAPREVTSDSGSIVVSGLTP 1145
Query: 1014 STHYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSAL-ISWQ-PPRAEIEN 1070
Y T+ +G I T L PP NL L +SW+ +I
Sbjct: 1146 GVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG 1205
Query: 1071 YVLTYKSTDGSR---KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
Y +T T+G + E +V A+ + + L +Y V + +D
Sbjct: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 353 bits (906), Expect = 6e-97
Identities = 262/867 (30%), Positives = 409/867 (47%), Gaps = 52/867 (5%)
Query: 293 GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351
G++ +N E+ L + PD APP D V + D SI + W P A
Sbjct: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
Query: 352 VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
+T Y I Y P+ G + +P + VT+++L+PG+ YNI++YAV N S P+ +
Sbjct: 838 ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
Query: 412 AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
T + +P+ LQF +T+ V + W P + G+ + IP N G ++P
Sbjct: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
Query: 465 DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523
+F + TGL PG Y V A+ S P +A +T +D PT + + +D+ V
Sbjct: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
Query: 524 WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
W PPRA++ L GL G + + P +S+Y ++ L+P S Y VS+ A++G ES
Sbjct: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
Query: 584 DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638
AT FTT P N V T T++ + W + A +K+ V + GE E
Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
Query: 639 VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697
V G ++ L PG EY I + + Q+ P T L P +L + A+
Sbjct: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
Query: 698 SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752
+T + ++ W +++ P I YRIT TP++ G + E V D++S T +L PG EY +
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
Query: 753 SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWS-DPSPPADRLILNYSPR 811
SV + ++S+ + P + L F+++ ++ +TW+ PS ++ YSP
Sbjct: 1246 SVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
Query: 812 DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDIT 871
EE++ E+S+ + VL L P TEY+V++ +V+ S P+ G TG+D P I
Sbjct: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
Query: 872 ISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEFTITRLNPATEYE 930
S++T +S V W P A+ YR+ + P GR VP++ T+T L P TEY
Sbjct: 1366 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
Query: 931 ISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHF 990
+S+ ++ GREES + T D P DL TPT L+ W AP V Y I T+
Sbjct: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRI--TYG 1483
Query: 991 AVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATNG----PLTSGTISTNFSTLLD 1042
G + V G + L P YT T+YA G P +S IS N+ T +D
Sbjct: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
Query: 1043 PPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSRKELIVDAEDTWIRLEGLL 1100
P+ + ++V S + W P + + Y T K+ G K + T + +EGL
Sbjct: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
Query: 1101 ENTDYTVLLQAAQDTTWSS-ITSTAFT 1126
+Y V + A + S + TA T
Sbjct: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVT 1630
Score = 335 bits (860), Expect = 1e-91
Identities = 238/812 (29%), Positives = 379/812 (46%), Gaps = 30/812 (3%)
Query: 326 VAPPEDLRVAGISDRSI-ELEWDGPMA--VTEYVISYQPT-ALGGLQLQQRVPGDWSGVT 381
++PP +L + D + + W+ +T Y I+ PT G L++ V D S T
Sbjct: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
Query: 382 ITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SF 440
L PGL YN+SVY V + S+PI+ + + P L+F I T+ V W P S
Sbjct: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
Query: 441 SFDGWEISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSA 498
+ + + P NE V ++ PSD + T L PG EY+V+V ++ EQ S P
Sbjct: 1294 DLTNFLVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
Query: 499 SVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQ 558
T +D PT I D++ V WI PRA + +++ G R+ +
Sbjct: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
Query: 559 YSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSE 618
++ L PG+ Y VS+ A+ G ES Q +T D P++L V + T TSL + WD
Sbjct: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 619 AEVQEYKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQ 673
V+ Y++ Y G E VP G + AT++ L PG +Y + + AV +
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
Query: 674 QSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVT 731
S P ++N RTE+D P + VT + SIS+ W +S P+ YR+T TP +G T
Sbjct: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
D+T T+ L+P EY++SV A+ +S A T L F+ V S+
Sbjct: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1649
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
I W P R + YS ++ + + D + A L GL+P +EY V++VA+H +
Sbjct: 1650 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1709
Query: 852 TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSV 910
S+P++G+ +T I P D+ + VT S+ W+PP YRV P + G +
Sbjct: 1710 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1769
Query: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPT 967
+ + ++ L AT+YE+S+ +++ S R V T ++N P T+ T T
Sbjct: 1770 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATET 1828
Query: 968 EALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYAT 1024
+ W+ + + + G+T + + + R + L P T Y +Y
Sbjct: 1829 TITISWRTKTETITGFQV--DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1886
Query: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKE 1084
N S + + ST +D P+NL T S L+SWQPPRA I Y++ Y+ +E
Sbjct: 1887 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1946
Query: 1085 LIVDAED--TWIRLEGLLENTDYTVLLQAAQD 1114
++ T + GL T+YT+ + A ++
Sbjct: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
Score = 274 bits (700), Expect = 5e-73
Identities = 208/812 (25%), Positives = 357/812 (43%), Gaps = 24/812 (2%)
Query: 321 PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379
P V P DL+ ++D + + W P AVT Y + P L G Q+ +
Sbjct: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
Query: 380 VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439
+T L PG+TY V+AV S P+TA+ T L P LQF T++TV V+W P
Sbjct: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
G+ ++ V V+ + L+P EY V++VA+K SP +
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 500 VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557
+T+ G + +V++T + W P PR I K G+ +GG +
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
Query: 558 QYSVQALRPGSRYEVSVSAVRGTNESDS-ATTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615
V L PG Y ++ +R E D+ + T + P NL + + T L + W+
Sbjct: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
Query: 616 NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
S ++ Y++ + G+Q + L + T +L PG EY V + V + ++
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWT-KASGPIDHYRITFTP--SSGIASEVT 731
SVP + + P DL T ++ + W S + ++ + ++P + +E++
Sbjct: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
+ + LT+L PG EY++SV++ + +S TG + + FS +T++S
Sbjct: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
Query: 792 ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851
+ W P + + P E + ++ L L P TEY+V++VA++G
Sbjct: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
Query: 852 TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGR-LDSSV 910
S ++G +T D P+D+ + T S+++SW P + YYR++Y T +
Sbjct: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1495
Query: 911 VPNTVTEFTITRLNPATEYEISLNSVRGREE----SERICTLVHTAMDNPVDLIATNITP 966
VP + + TI+ L P +Y I++ +V GR + S+ I T +D P + T++
Sbjct: 1496 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1555
Query: 967 TEALLQWKAPVGEVENYVIVLTHFAVAG--ETILVDGVSEEFRLVDLLPSTHYTATMYAT 1024
++W V Y + T G +T E + L P+ Y ++YA
Sbjct: 1556 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1615
Query: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKE 1084
N S + T +D P L ++V S I+W+ P+ ++ Y +TY S + E
Sbjct: 1616 NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
Query: 1085 LI--VDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
L D E+ L+GL ++YTV + A D
Sbjct: 1676 LFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707
Score = 254 bits (650), Expect = 3e-67
Identities = 219/824 (26%), Positives = 351/824 (42%), Gaps = 26/824 (3%)
Query: 329 PEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEP 387
P +L+ +D ++ + W P A +T Y ++ T G + Q V S + L+P
Sbjct: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQP 1058
Query: 388 GLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKT-ITETTVEVQWEPFSFSFDGWE 446
Y +S+ A+ N S T T + T +TETT+ + W P G++
Sbjct: 1059 ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFK 1116
Query: 447 ISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKE-QARSPPTSASVSTVID 505
+ P G +V SD S +GL PG EY+ + L++ Q R P V T +
Sbjct: 1117 LGVRPSQG-GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLS 1175
Query: 506 GPTQILVRDVSDT-VAFVEWIPPRAK--VDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562
PT + + DT V V W + + G +G + S +
Sbjct: 1176 PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
Query: 563 ALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEA-EV 621
L PG Y VSV V+ ES + + P +LR + ++ + W + ++
Sbjct: 1236 NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDL 1295
Query: 622 QEYKVVYSTLAGEQYHEVLVPRGIGPTTRAT-LTDLVPGTEYGVGISAVMNSQQSVPATM 680
+ V YS + E E + I P+ A LT+L+PGTEY V +S+V +S P
Sbjct: 1296 TNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
Query: 681 NARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTS 738
+T LDSP + + + S ++ W I YRI P SG E VP R S
Sbjct: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
Query: 739 YTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPS 798
TLT+L PG EY++S+ A GR++S T L T +S+ I+W P+
Sbjct: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
Query: 799 PPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT----VTSE 854
+ Y + E ++ +K A + GL+P +Y + + AV G +S+
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
Query: 855 PIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPN 913
PI + T ID P + +++V +S+ V W P + YRV+ P G +
Sbjct: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1592
Query: 914 TVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQW 973
TE TI L P EY +S+ + ES+ + T +D P L T++ + W
Sbjct: 1593 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAW 1652
Query: 974 KAPVGEVENYVIVLTHFAVAGETILV--DGVSEEFRLVDLLPSTHYTATMYATNGPLTSG 1031
++P G+V Y + + + DG + L L P + YT ++ A + + S
Sbjct: 1653 ESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQ 1712
Query: 1032 TISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVL--TYKSTDGSRKELIVDA 1089
+ ST + P +L ++VT S W PP ++ Y + T K G KE+ +
Sbjct: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
Query: 1090 EDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
+ + + + GL+ T Y V + A +DT S TT V P
Sbjct: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
Score = 245 bits (626), Expect = 2e-64
Identities = 215/816 (26%), Positives = 355/816 (43%), Gaps = 61/816 (7%)
Query: 344 LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391
++W+ P +++Y++ ++P G + +PG + TI L+PG+ Y
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 392 ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442
++ + + S P+T+ T +TP T IT ++ V W S +
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 443 DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500
G+ + + + + + +PS TS N L PG +YIVNV + E +S S S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
+T D P V V DT V W P+A + + Y EG T L + +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
Query: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613
+ L+PG +Y +++ AV ES Q T + +P++L+ T + +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 614 WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
W E+ V Y+ V+ L GE + + R T A +T L PG Y + AV +
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
Query: 672 SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730
++S P T T+LD+P +L +++++ + WT I YR+T G +
Sbjct: 983 GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788
V + Y L +L+P +EY +S+ A +G Q+S ++T FT +P S + + + VT +
Sbjct: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
Query: 789 SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845
++ ITW+ PA R+ L P E EV+ D+ V+ GL P EY+ + V
Sbjct: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
Query: 846 AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901
G PIV + T + PP ++ + +N + VSW YR++ PT
Sbjct: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
Query: 902 QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961
Q G VV + T L+P EY +S+ +V+ +ES I + A+ P DL
Sbjct: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
Query: 962 TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE----TILVDGVSEEFRLVDLLPSTHY 1017
TNI P + W AP ++ ++ + V E + + L +LLP T Y
Sbjct: 1276 TNIGPDTMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1334
Query: 1018 TATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY-- 1075
++ + S + T LD P + S++T S + W PRA I Y + +
Sbjct: 1335 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1394
Query: 1076 KSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111
+ G +E V I L L T+Y V + A
Sbjct: 1395 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
Score = 244 bits (622), Expect = 5e-64
Identities = 176/651 (27%), Positives = 293/651 (45%), Gaps = 18/651 (2%)
Query: 319 QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377
+G + + P + + I+ S + W P A +T Y I + P G + RVP
Sbjct: 1351 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
Query: 378 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
+ +T+T L PG Y +S+ A+ S + + +T P+ L+ T T++ + W+
Sbjct: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
Query: 438 FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
+ + + I++ V VP ++ +GLKPG +Y + V A+ + SP +
Sbjct: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
Query: 497 SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
S +S T ID P+Q+ V DV D V+W+P + V + G G T
Sbjct: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
Query: 553 QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
P ++ +++ L+P Y VSV A + ES T ID PK L S+ +
Sbjct: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1650
Query: 613 EWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNS 672
W++ + +V Y+V YS+ + HE L P G A L L PG+EY V + A+ +
Sbjct: 1651 AWESPQGQVSRYRVTYSS-PEDGIHE-LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD 1708
Query: 673 QQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEV 730
+S P T + +P DL T + TS+S WT + + YR+ TP +G E+
Sbjct: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1768
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSS 788
+ D +S ++ L +Y +SV A + S + V P + T +
Sbjct: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1828
Query: 789 SVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVH 848
++ I+W + ++ P + + + ++ R + GLQP T+Y + L ++
Sbjct: 1829 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
Query: 849 GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDS 908
S P+V +T ID P ++ T +S++VSW PP A Y + Y + G
Sbjct: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPR 1945
Query: 909 SVVPNT---VTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNP 956
VVP VTE TIT L P TEY I + +++ ++SE + T P
Sbjct: 1946 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
Score = 166 bits (421), Expect = 1e-40
Identities = 159/647 (24%), Positives = 273/647 (42%), Gaps = 42/647 (6%)
Query: 506 GPTQILVRDVSDTVAF--VEWIPPR-AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562
GP ++ + + ++W P+ + + +L++ G + L+ Y+++
Sbjct: 610 GPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIK 669
Query: 563 ALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPKNLRVGSRTATSLDLEWDNSEA 619
L+PG YE + +++ + FTT N G T S + S
Sbjct: 670 GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
Query: 620 EVQEYKVVYS------TLAGEQYHEVLVPRGIGP--------TTRATLTDLVPGTEYGVG 665
E+ V S T++G + L G P T + DL+PG +Y V
Sbjct: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
Query: 666 ISAVM-NSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS- 723
+ + + +QS+ + + T D+P D V +TSI + W++ PI YRI ++PS
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
Query: 724 SGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISH---- 779
G ++E+ +P+ S TL+DL+PG +Y I++ A Q+S + T P S
Sbjct: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
Query: 780 ---LHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQP 836
L F VT V I W+ P ++ P + E + + A + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 837 ATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896
Y + AV S+P+ TT +D P ++ N T +V+V W+PP A YR+
Sbjct: 970 GVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRL 1029
Query: 897 SYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMD-- 954
+ T+ G+ V +V+++ + L PA+EY +SL +++G +ES + T V T +
Sbjct: 1030 TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK-ATGVFTTLQPG 1088
Query: 955 NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETIL-VDGVSEEFRLVDLLP 1013
+ + T +T T ++ W P + + V + GE V S + L P
Sbjct: 1089 SSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRP--SQGGEAPREVTSDSGSIVVSGLTP 1145
Query: 1014 STHYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSAL-ISWQ-PPRAEIEN 1070
Y T+ +G I T L PP NL L +SW+ +I
Sbjct: 1146 GVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG 1205
Query: 1071 YVLTYKSTDGSR---KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
Y +T T+G + E +V A+ + + L +Y V + +D
Sbjct: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
Score = 131 bits (330), Expect = 4e-30
Identities = 77/296 (26%), Positives = 136/296 (45%), Gaps = 3/296 (1%)
Query: 320 GPDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWS 378
G +A+ P DL+ ++ S+ +W P + +T Y + P G + + D S
Sbjct: 1716 GTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSS 1775
Query: 379 GVTITELEPGLTYNISVYAVISNILSLPITAKVAT--HLSTPQGLQFKTITETTVEVQWE 436
V ++ L Y +SVYA+ + S P V T ++S P+ + TETT+ + W
Sbjct: 1776 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1835
Query: 437 PFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
+ + G+++ +P N + + + DV S+ TGL+PG +Y + + L + ARS P
Sbjct: 1836 TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1895
Query: 497 SASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPL 556
ST ID P+ + + V W PPRA++ ++KY G R +P +
Sbjct: 1896 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1955
Query: 557 SQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
++ ++ L PG+ Y + V A++ +S+ + T P G T + L
Sbjct: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQL 2011
Score = 48.9 bits (115), Expect = 3e-05
Identities = 57/225 (25%), Positives = 84/225 (37%), Gaps = 57/225 (25%)
Query: 324 SAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTI 382
+A+ P +LR + S+ + W P A +T Y+I Y+ ++ R + TI
Sbjct: 1901 TAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1960
Query: 383 TELEPGLTYNISVYAVISNILSLPITAKVATHLSTP----------QGLQF--------- 423
T LEPG Y I V A+ +N S P+ + T TP G+Q
Sbjct: 1961 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 2020
Query: 424 -------------KTITETTVE----------------------VQWEPFSFSFDGWEIS 448
+T TT + W PF + + + IS
Sbjct: 2021 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE-YIIS 2079
Query: 449 FIPKN-NEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQAR 492
P +E + +VP TS TGL G Y + V ALK+Q R
Sbjct: 2080 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2124
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 329 bits (844), Expect = 1e-89
Identities = 237/807 (29%), Positives = 374/807 (46%), Gaps = 32/807 (3%)
Query: 331 DLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGLQ----LQQRVPGDWSGVTITELE 386
DL I+D SI L W + T +I Y+ T + + + V T+T LE
Sbjct: 1272 DLSFVDITDSSIGLRWTPLNSST--IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE 1329
Query: 387 PGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SFSFDGW 445
PG+ Y+ISV +I+ S P T T + P L+F I T+ V W P S +
Sbjct: 1330 PGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNF 1389
Query: 446 EISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTV 503
+ + P NE V ++ PSD + T L PG EY+V+V ++ EQ S P T
Sbjct: 1390 LVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1448
Query: 504 IDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQA 563
+D PT I D++ V WI PRA + +++ G R+ + ++
Sbjct: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
Query: 564 LRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQE 623
L PG+ Y VS+ A+ G ES Q +T D P++L V + T TSL + WD V+
Sbjct: 1509 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1568
Query: 624 YKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQQSVPA 678
Y++ Y G E VP G + AT++ L PG +Y + + AV + S P
Sbjct: 1569 YRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625
Query: 679 TMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVTVPKDR 736
++N RTE+D P + VT + SIS+ W +S P+ YR+T TP +G T D+
Sbjct: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
Query: 737 TSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSD 796
T T+ L+P EY++SV A+ +S A T L F+ V S+ I W
Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1745
Query: 797 PSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPI 856
P R + YS ++ + + D + A L GL+P +EY V++VA+H + S+P+
Sbjct: 1746 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1805
Query: 857 VGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTV 915
+G+ +T I P D+ + VT S+ W+PP YRV P + G + +
Sbjct: 1806 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
Query: 916 TEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPTEALLQ 972
+ ++ L AT+YE+S+ +++ S R V T ++N P T+ T T +
Sbjct: 1866 SSVVVSGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
Query: 973 WKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYATNGPLT 1029
W+ + + + G+T + + + R + L P T Y +Y N
Sbjct: 1925 WRTKTETITGFQV--DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1982
Query: 1030 SGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDA 1089
S + + ST +D P+NL T S L+SWQPPRA I Y++ Y+ +E++
Sbjct: 1983 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRP 2042
Query: 1090 ED--TWIRLEGLLENTDYTVLLQAAQD 1114
T + GL T+YT+ + A ++
Sbjct: 2043 RPGVTEATITGLEPGTEYTIYVIALKN 2069
Score = 315 bits (807), Expect = 2e-85
Identities = 243/828 (29%), Positives = 372/828 (44%), Gaps = 30/828 (3%)
Query: 321 PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379
P V P DL+ ++D + + W P AVT Y + P L G Q+ +
Sbjct: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
Query: 380 VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439
+T L PG+TY V+AV S P+TA+ T L P LQF T++TV V+W P
Sbjct: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
G+ ++ V V+ + L+P EY V++VA+K SP +
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 500 VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557
+T+ G + +V++T + W P PR I K G+ +GG +
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
Query: 558 QYSVQALRPGSRYEVSVSAVRGTNESDS-ATTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615
V L PG Y ++ +R E D+ + T + P NL + + T L + W+
Sbjct: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
Query: 616 NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
S ++ Y++ + G+Q + L + T +L PG EY V + V + ++
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWTKA-SGPIDHYRITFTPS-SGI-ASEVT 731
SVP + E+ DL +++SI L WT S I YRIT + GI E
Sbjct: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDF 1315
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
V YT+T LEPG +Y ISV +S +T+ T P + L F+++ ++
Sbjct: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMR 1375
Query: 792 ITWS-DPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT 850
+TW+ PS ++ YSP EE++ E+S+ + VL L P TEY+V++ +V+
Sbjct: 1376 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1435
Query: 851 VTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSS 909
S P+ G TG+D P I S++T +S V W P A+ YR+ + P GR
Sbjct: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1495
Query: 910 VVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969
VP++ T+T L P TEY +S+ ++ GREES + T D P DL TPT
Sbjct: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
Query: 970 LLQWKAPVGEVENYVIVLTHFAVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATN 1025
L+ W AP V Y I T+ G + V G + L P YT T+YA
Sbjct: 1556 LISWDAPAVTVRYYRI--TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT 1613
Query: 1026 G----PLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTD 1079
G P +S IS N+ T +D P+ + ++V S + W P + + Y T K+
Sbjct: 1614 GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGP 1673
Query: 1080 GSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSS-ITSTAFT 1126
G K + T + +EGL +Y V + A + S + TA T
Sbjct: 1674 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
Score = 308 bits (788), Expect = 3e-83
Identities = 243/852 (28%), Positives = 391/852 (45%), Gaps = 56/852 (6%)
Query: 293 GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351
G++ +N E+ L + PD APP D V + D SI + W P A
Sbjct: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
Query: 352 VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
+T Y I Y P+ G + +P + VT+++L+PG+ YNI++YAV N S P+ +
Sbjct: 838 ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
Query: 412 AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
T + +P+ LQF +T+ V + W P + G+ + IP N G ++P
Sbjct: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
Query: 465 DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523
+F + TGL PG Y V A+ S P +A +T +D PT + + +D+ V
Sbjct: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
Query: 524 WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
W PPRA++ L GL G + + P +S+Y ++ L+P S Y VS+ A++G ES
Sbjct: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
Query: 584 DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638
AT FTT P N V T T++ + W + A +K+ V + GE E
Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
Query: 639 VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697
V G ++ L PG EY I + + Q+ P T L P +L + A+
Sbjct: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
Query: 698 SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752
+T + ++ W +++ P I YRIT TP++ G + E V D++S T +L PG EY +
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
Query: 753 SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYS--- 809
SV + ++S+ + ++ L F +T SS+ + W +P I+ Y
Sbjct: 1246 SVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW---TPLNSSTIIGYRITV 1302
Query: 810 -PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPK 868
E + E +D++ + + GL+P +Y ++++ + S P + T + PP
Sbjct: 1303 VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT 1362
Query: 869 DITISNVTKDSVMVSWSPPVA-SFDYYRVSYRPTQ----VGRLDSSVVPNTVTEFTITRL 923
D+ +N+ D++ V+W+PP + + V Y P + V L S N V +T L
Sbjct: 1363 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV---VLTNL 1419
Query: 924 NPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENY 983
P TEY +S++SV + ES + T +D+P + ++IT + W AP + Y
Sbjct: 1420 LPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY 1479
Query: 984 VI--VLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLL 1041
I HF+ V L +L P T Y ++ A NG S + ST+
Sbjct: 1480 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS 1539
Query: 1042 DPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSR--KELIVDAEDTWIRLEGL 1099
D P +L T S LISW P + Y +TY T G+ +E V + + GL
Sbjct: 1540 DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1599
Query: 1100 LENTDYTVLLQA 1111
DYT+ + A
Sbjct: 1600 KPGVDYTITVYA 1611
Score = 265 bits (676), Expect = 3e-70
Identities = 216/817 (26%), Positives = 357/817 (43%), Gaps = 27/817 (3%)
Query: 337 ISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVY 396
+++ +I + W P + + +P+ G + + V D + ++ L PG+ Y ++
Sbjct: 1098 VTETTIVITWT-PAPRIGFKLGVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
Query: 397 AVISNI-LSLPITAKVATHLSTPQGLQFKTITETTV-EVQWEPFSF-SFDGWEISFIPKN 453
+ PI KV T LS P L + +T V V WE + G+ I+ P N
Sbjct: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
Query: 454 NEGGVIAQ--VPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQIL 511
+ G + V +D +S L PG EY V+V +K+ S P S ++ + T +
Sbjct: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLS 1274
Query: 512 VRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFR--LQPPLSQYSVQALRPGSR 569
D++D+ + W P + I + +V G F + + Y+V L PG
Sbjct: 1275 FVDITDSSIGLRWTPLNSST-IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGID 1333
Query: 570 YEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEA-EVQEYKVVY 628
Y++SV + ES T T + P +LR + ++ + W + ++ + V Y
Sbjct: 1334 YDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRY 1393
Query: 629 STLAGEQYHEVLVPRGIGPTTRAT-LTDLVPGTEYGVGISAVMNSQQSVPATMNARTELD 687
S + E E + I P+ A LT+L+PGTEY V +S+V +S P +T LD
Sbjct: 1394 SPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
Query: 688 SPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTSYTLTDLE 745
SP + + + S ++ W I YRI P SG E VP R S TLT+L
Sbjct: 1451 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
Query: 746 PGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLI 805
PG EY++S+ A GR++S T L T +S+ I+W P+
Sbjct: 1511 PGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYR 1570
Query: 806 LNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT----VTSEPIVGSIT 861
+ Y + E ++ +K A + GL+P +Y + + AV G +S+PI +
Sbjct: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYR 1630
Query: 862 TGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTVTEFTI 920
T ID P + +++V +S+ V W P + YRV+ P G + TE TI
Sbjct: 1631 TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
Query: 921 TRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEV 980
L P EY +S+ + ES+ + T +D P L T++ + W++P G+V
Sbjct: 1691 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
Query: 981 ENYVIVLTHFAVAGETILV--DGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFS 1038
Y + + + DG + L L P + YT ++ A + + S + S
Sbjct: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
Query: 1039 TLLDPPANLTASEVTRQSALISWQPPRAEIENYVL--TYKSTDGSRKELIVDAEDTWIRL 1096
T + P +L ++VT S W PP ++ Y + T K G KE+ + + + + +
Sbjct: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
Query: 1097 EGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
GL+ T Y V + A +DT S TT V P
Sbjct: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1907
Score = 243 bits (620), Expect = 9e-64
Identities = 217/855 (25%), Positives = 356/855 (41%), Gaps = 53/855 (6%)
Query: 319 QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377
+G + + P + + I+ S + W P A +T Y I + P G + RVP
Sbjct: 1442 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1501
Query: 378 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
+ +T+T L PG Y +S+ A+ S + + +T P+ L+ T T++ + W+
Sbjct: 1502 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
Query: 438 FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
+ + + I++ V VP ++ +GLKPG +Y + V A+ + SP +
Sbjct: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
Query: 497 SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
S +S T ID P+Q+ V DV D V+W+P + V + G G T
Sbjct: 1622 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
Query: 553 QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
P ++ +++ L+P Y VSV A + ES T ID PK L S+ +
Sbjct: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1741
Query: 613 EWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNS 672
W++ + +V Y+V YS+ + HE L P G A L L PG+EY V + A+ +
Sbjct: 1742 AWESPQGQVSRYRVTYSS-PEDGIHE-LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD 1799
Query: 673 QQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEV 730
+S P T + +P DL T + TS+S WT + + YR+ TP +G E+
Sbjct: 1800 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSS 788
+ D +S ++ L +Y +SV A + S + V P + T +
Sbjct: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1919
Query: 789 SVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVH 848
++ I+W + ++ P + + + ++ R + GLQP T+Y + L ++
Sbjct: 1920 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
Query: 849 GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDS 908
S P+V +T ID P ++ T +S++VSW PP A Y + Y + G
Sbjct: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPR 2036
Query: 909 SVVPNT---VTEFTITRLNPATEYEISLNSVRGREESE------------RICTLVHTAM 953
VVP VTE TIT L P TEY I + +++ ++SE ++ TL H +
Sbjct: 2037 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNL 2096
Query: 954 DNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLP 1013
P L ++ T + G I L + ++ + EE P
Sbjct: 2097 HGPEIL---DVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTP 2153
Query: 1014 STHYTATMYATN--GPLTSGTISTNFSTLLD---------PPANLTASEVTRQSAL---- 1058
T T + P I D P N AS T Q AL
Sbjct: 2154 PTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNAS--TGQEALSQTT 2211
Query: 1059 ISWQPPRAEIENYVLTYK--STDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTT 1116
ISW P + + Y+++ TD + V T L GL Y ++++A +D
Sbjct: 2212 ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 2270
Query: 1117 WSSITSTAFTTGGRV 1131
+ T G V
Sbjct: 2271 RHKVREEVVTVGNSV 2285
Score = 237 bits (604), Expect = 6e-62
Identities = 228/901 (25%), Positives = 383/901 (42%), Gaps = 108/901 (11%)
Query: 344 LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391
++W+ P +++Y++ ++P G + +PG + TI L+PG+ Y
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 392 ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442
++ + + S P+T+ T +TP T IT ++ V W S +
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 443 DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500
G+ + + + + + +PS TS N L PG +YIVNV + E +S S S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
+T D P V V DT V W P+A + + Y EG T L + +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
Query: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613
+ L+PG +Y +++ AV ES Q T + +P++L+ T + +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 614 WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
W E+ V Y+ V+ L GE + + R T A +T L PG Y + AV +
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
Query: 672 SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730
++S P T T+LD+P +L +++++ + WT I YR+T G +
Sbjct: 983 GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788
V + Y L +L+P +EY +S+ A +G Q+S ++T FT +P S + + + VT +
Sbjct: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
Query: 789 SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845
++ ITW+ PA R+ L P E EV+ D+ V+ GL P EY+ + V
Sbjct: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
Query: 846 AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901
G PIV + T + PP ++ + +N + VSW YR++ PT
Sbjct: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
Query: 902 QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961
Q G VV + T L+P EY +S+ +V+ +ES I + + DL
Sbjct: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
Query: 962 TNITPTEALLQWKAPVGE--VENYVIVLTHFAVAGETI-----LVDGVSEEFRLVDLLPS 1014
+IT + L+W P+ + Y I + AGE I VD + + L P
Sbjct: 1276 VDITDSSIGLRW-TPLNSSTIIGYRITV---VAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
Query: 1015 THYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRA-EIENYV 1072
Y ++ NG ++ T T T + PP +L + + + ++W PP + ++ N++
Sbjct: 1332 IDYDISVITLINGGESAPTTLTQ-QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1390
Query: 1073 LTYKSTDGSR--KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD---------------- 1114
+ Y EL + D + L LL T+Y V + + +
Sbjct: 1391 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
Query: 1115 ----TTWSSITSTAFT----------TGGRVFPHP--------QDCAQHLMNGDTLSGVY 1152
+S IT+ +FT TG R+ HP +D H N TL+ +
Sbjct: 1451 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
Query: 1153 P 1153
P
Sbjct: 1511 P 1511
Score = 166 bits (421), Expect = 1e-40
Identities = 159/647 (24%), Positives = 273/647 (42%), Gaps = 42/647 (6%)
Query: 506 GPTQILVRDVSDTVAF--VEWIPPR-AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562
GP ++ + + ++W P+ + + +L++ G + L+ Y+++
Sbjct: 610 GPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIK 669
Query: 563 ALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPKNLRVGSRTATSLDLEWDNSEA 619
L+PG YE + +++ + FTT N G T S + S
Sbjct: 670 GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
Query: 620 EVQEYKVVYS------TLAGEQYHEVLVPRGIGP--------TTRATLTDLVPGTEYGVG 665
E+ V S T++G + L G P T + DL+PG +Y V
Sbjct: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
Query: 666 ISAVM-NSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS- 723
+ + + +QS+ + + T D+P D V +TSI + W++ PI YRI ++PS
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
Query: 724 SGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISH---- 779
G ++E+ +P+ S TL+DL+PG +Y I++ A Q+S + T P S
Sbjct: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
Query: 780 ---LHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQP 836
L F VT V I W+ P ++ P + E + + A + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 837 ATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896
Y + AV S+P+ TT +D P ++ N T +V+V W+PP A YR+
Sbjct: 970 GVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRL 1029
Query: 897 SYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMD-- 954
+ T+ G+ V +V+++ + L PA+EY +SL +++G +ES + T V T +
Sbjct: 1030 TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK-ATGVFTTLQPG 1088
Query: 955 NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETIL-VDGVSEEFRLVDLLP 1013
+ + T +T T ++ W P + + V + GE V S + L P
Sbjct: 1089 SSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRP--SQGGEAPREVTSDSGSIVVSGLTP 1145
Query: 1014 STHYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSAL-ISWQ-PPRAEIEN 1070
Y T+ +G I T L PP NL L +SW+ +I
Sbjct: 1146 GVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG 1205
Query: 1071 YVLTYKSTDGSR---KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
Y +T T+G + E +V A+ + + L +Y V + +D
Sbjct: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 329 bits (844), Expect = 1e-89
Identities = 237/807 (29%), Positives = 374/807 (46%), Gaps = 32/807 (3%)
Query: 331 DLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGLQ----LQQRVPGDWSGVTITELE 386
DL I+D SI L W + T +I Y+ T + + + V T+T LE
Sbjct: 1272 DLSFVDITDSSIGLRWTPLNSST--IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE 1329
Query: 387 PGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SFSFDGW 445
PG+ Y+ISV +I+ S P T T + P L+F I T+ V W P S +
Sbjct: 1330 PGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNF 1389
Query: 446 EISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTV 503
+ + P NE V ++ PSD + T L PG EY+V+V ++ EQ S P T
Sbjct: 1390 LVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1448
Query: 504 IDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQA 563
+D PT I D++ V WI PRA + +++ G R+ + ++
Sbjct: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
Query: 564 LRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQE 623
L PG+ Y VS+ A+ G ES Q +T D P++L V + T TSL + WD V+
Sbjct: 1509 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1568
Query: 624 YKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQQSVPA 678
Y++ Y G E VP G + AT++ L PG +Y + + AV + S P
Sbjct: 1569 YRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625
Query: 679 TMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVTVPKDR 736
++N RTE+D P + VT + SIS+ W +S P+ YR+T TP +G T D+
Sbjct: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
Query: 737 TSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSD 796
T T+ L+P EY++SV A+ +S A T L F+ V S+ I W
Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1745
Query: 797 PSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPI 856
P R + YS ++ + + D + A L GL+P +EY V++VA+H + S+P+
Sbjct: 1746 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1805
Query: 857 VGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTV 915
+G+ +T I P D+ + VT S+ W+PP YRV P + G + +
Sbjct: 1806 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
Query: 916 TEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPTEALLQ 972
+ ++ L AT+YE+S+ +++ S R V T ++N P T+ T T +
Sbjct: 1866 SSVVVSGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
Query: 973 WKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYATNGPLT 1029
W+ + + + G+T + + + R + L P T Y +Y N
Sbjct: 1925 WRTKTETITGFQV--DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1982
Query: 1030 SGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDA 1089
S + + ST +D P+NL T S L+SWQPPRA I Y++ Y+ +E++
Sbjct: 1983 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRP 2042
Query: 1090 ED--TWIRLEGLLENTDYTVLLQAAQD 1114
T + GL T+YT+ + A ++
Sbjct: 2043 RPGVTEATITGLEPGTEYTIYVIALKN 2069
Score = 315 bits (807), Expect = 2e-85
Identities = 243/828 (29%), Positives = 372/828 (44%), Gaps = 30/828 (3%)
Query: 321 PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379
P V P DL+ ++D + + W P AVT Y + P L G Q+ +
Sbjct: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
Query: 380 VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439
+T L PG+TY V+AV S P+TA+ T L P LQF T++TV V+W P
Sbjct: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
Query: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
G+ ++ V V+ + L+P EY V++VA+K SP +
Sbjct: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
Query: 500 VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557
+T+ G + +V++T + W P PR I K G+ +GG +
Sbjct: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
Query: 558 QYSVQALRPGSRYEVSVSAVRGTNESDS-ATTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615
V L PG Y ++ +R E D+ + T + P NL + + T L + W+
Sbjct: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
Query: 616 NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
S ++ Y++ + G+Q + L + T +L PG EY V + V + ++
Sbjct: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
Query: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWTKA-SGPIDHYRITFTPS-SGI-ASEVT 731
SVP + E+ DL +++SI L WT S I YRIT + GI E
Sbjct: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDF 1315
Query: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
V YT+T LEPG +Y ISV +S +T+ T P + L F+++ ++
Sbjct: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMR 1375
Query: 792 ITWS-DPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT 850
+TW+ PS ++ YSP EE++ E+S+ + VL L P TEY+V++ +V+
Sbjct: 1376 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1435
Query: 851 VTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSS 909
S P+ G TG+D P I S++T +S V W P A+ YR+ + P GR
Sbjct: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1495
Query: 910 VVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969
VP++ T+T L P TEY +S+ ++ GREES + T D P DL TPT
Sbjct: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
Query: 970 LLQWKAPVGEVENYVIVLTHFAVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATN 1025
L+ W AP V Y I T+ G + V G + L P YT T+YA
Sbjct: 1556 LISWDAPAVTVRYYRI--TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT 1613
Query: 1026 G----PLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTD 1079
G P +S IS N+ T +D P+ + ++V S + W P + + Y T K+
Sbjct: 1614 GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGP 1673
Query: 1080 GSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSS-ITSTAFT 1126
G K + T + +EGL +Y V + A + S + TA T
Sbjct: 1674 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
Score = 308 bits (788), Expect = 3e-83
Identities = 243/852 (28%), Positives = 391/852 (45%), Gaps = 56/852 (6%)
Query: 293 GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351
G++ +N E+ L + PD APP D V + D SI + W P A
Sbjct: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
Query: 352 VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
+T Y I Y P+ G + +P + VT+++L+PG+ YNI++YAV N S P+ +
Sbjct: 838 ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
Query: 412 AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
T + +P+ LQF +T+ V + W P + G+ + IP N G ++P
Sbjct: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
Query: 465 DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523
+F + TGL PG Y V A+ S P +A +T +D PT + + +D+ V
Sbjct: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
Query: 524 WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
W PPRA++ L GL G + + P +S+Y ++ L+P S Y VS+ A++G ES
Sbjct: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
Query: 584 DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638
AT FTT P N V T T++ + W + A +K+ V + GE E
Sbjct: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
Query: 639 VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697
V G ++ L PG EY I + + Q+ P T L P +L + A+
Sbjct: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
Query: 698 SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752
+T + ++ W +++ P I YRIT TP++ G + E V D++S T +L PG EY +
Sbjct: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
Query: 753 SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYS--- 809
SV + ++S+ + ++ L F +T SS+ + W +P I+ Y
Sbjct: 1246 SVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW---TPLNSSTIIGYRITV 1302
Query: 810 -PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPK 868
E + E +D++ + + GL+P +Y ++++ + S P + T + PP
Sbjct: 1303 VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT 1362
Query: 869 DITISNVTKDSVMVSWSPPVA-SFDYYRVSYRPTQ----VGRLDSSVVPNTVTEFTITRL 923
D+ +N+ D++ V+W+PP + + V Y P + V L S N V +T L
Sbjct: 1363 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV---VLTNL 1419
Query: 924 NPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENY 983
P TEY +S++SV + ES + T +D+P + ++IT + W AP + Y
Sbjct: 1420 LPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY 1479
Query: 984 VI--VLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLL 1041
I HF+ V L +L P T Y ++ A NG S + ST+
Sbjct: 1480 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS 1539
Query: 1042 DPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSR--KELIVDAEDTWIRLEGL 1099
D P +L T S LISW P + Y +TY T G+ +E V + + GL
Sbjct: 1540 DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1599
Query: 1100 LENTDYTVLLQA 1111
DYT+ + A
Sbjct: 1600 KPGVDYTITVYA 1611
Score = 265 bits (676), Expect = 3e-70
Identities = 216/817 (26%), Positives = 357/817 (43%), Gaps = 27/817 (3%)
Query: 337 ISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVY 396
+++ +I + W P + + +P+ G + + V D + ++ L PG+ Y ++
Sbjct: 1098 VTETTIVITWT-PAPRIGFKLGVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
Query: 397 AVISNI-LSLPITAKVATHLSTPQGLQFKTITETTV-EVQWEPFSF-SFDGWEISFIPKN 453
+ PI KV T LS P L + +T V V WE + G+ I+ P N
Sbjct: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
Query: 454 NEGGVIAQ--VPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQIL 511
+ G + V +D +S L PG EY V+V +K+ S P S ++ + T +
Sbjct: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLS 1274
Query: 512 VRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFR--LQPPLSQYSVQALRPGSR 569
D++D+ + W P + I + +V G F + + Y+V L PG
Sbjct: 1275 FVDITDSSIGLRWTPLNSST-IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGID 1333
Query: 570 YEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEA-EVQEYKVVY 628
Y++SV + ES T T + P +LR + ++ + W + ++ + V Y
Sbjct: 1334 YDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRY 1393
Query: 629 STLAGEQYHEVLVPRGIGPTTRAT-LTDLVPGTEYGVGISAVMNSQQSVPATMNARTELD 687
S + E E + I P+ A LT+L+PGTEY V +S+V +S P +T LD
Sbjct: 1394 SPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
Query: 688 SPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTSYTLTDLE 745
SP + + + S ++ W I YRI P SG E VP R S TLT+L
Sbjct: 1451 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
Query: 746 PGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLI 805
PG EY++S+ A GR++S T L T +S+ I+W P+
Sbjct: 1511 PGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYR 1570
Query: 806 LNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT----VTSEPIVGSIT 861
+ Y + E ++ +K A + GL+P +Y + + AV G +S+PI +
Sbjct: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYR 1630
Query: 862 TGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTVTEFTI 920
T ID P + +++V +S+ V W P + YRV+ P G + TE TI
Sbjct: 1631 TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
Query: 921 TRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEV 980
L P EY +S+ + ES+ + T +D P L T++ + W++P G+V
Sbjct: 1691 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
Query: 981 ENYVIVLTHFAVAGETILV--DGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFS 1038
Y + + + DG + L L P + YT ++ A + + S + S
Sbjct: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
Query: 1039 TLLDPPANLTASEVTRQSALISWQPPRAEIENYVL--TYKSTDGSRKELIVDAEDTWIRL 1096
T + P +L ++VT S W PP ++ Y + T K G KE+ + + + + +
Sbjct: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
Query: 1097 EGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
GL+ T Y V + A +DT S TT V P
Sbjct: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1907
Score = 244 bits (622), Expect = 5e-64
Identities = 176/651 (27%), Positives = 293/651 (45%), Gaps = 18/651 (2%)
Query: 319 QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377
+G + + P + + I+ S + W P A +T Y I + P G + RVP
Sbjct: 1442 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1501
Query: 378 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
+ +T+T L PG Y +S+ A+ S + + +T P+ L+ T T++ + W+
Sbjct: 1502 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
Query: 438 FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
+ + + I++ V VP ++ +GLKPG +Y + V A+ + SP +
Sbjct: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
Query: 497 SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
S +S T ID P+Q+ V DV D V+W+P + V + G G T
Sbjct: 1622 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
Query: 553 QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
P ++ +++ L+P Y VSV A + ES T ID PK L S+ +
Sbjct: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1741
Query: 613 EWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNS 672
W++ + +V Y+V YS+ + HE L P G A L L PG+EY V + A+ +
Sbjct: 1742 AWESPQGQVSRYRVTYSS-PEDGIHE-LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD 1799
Query: 673 QQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEV 730
+S P T + +P DL T + TS+S WT + + YR+ TP +G E+
Sbjct: 1800 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSS 788
+ D +S ++ L +Y +SV A + S + V P + T +
Sbjct: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1919
Query: 789 SVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVH 848
++ I+W + ++ P + + + ++ R + GLQP T+Y + L ++
Sbjct: 1920 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
Query: 849 GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDS 908
S P+V +T ID P ++ T +S++VSW PP A Y + Y + G
Sbjct: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPR 2036
Query: 909 SVVPNT---VTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNP 956
VVP VTE TIT L P TEY I + +++ ++SE + T P
Sbjct: 2037 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
Score = 237 bits (604), Expect = 6e-62
Identities = 228/901 (25%), Positives = 383/901 (42%), Gaps = 108/901 (11%)
Query: 344 LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391
++W+ P +++Y++ ++P G + +PG + TI L+PG+ Y
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 392 ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442
++ + + S P+T+ T +TP T IT ++ V W S +
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 443 DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500
G+ + + + + + +PS TS N L PG +YIVNV + E +S S S
Sbjct: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
Query: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
+T D P V V DT V W P+A + + Y EG T L + +
Sbjct: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
Query: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613
+ L+PG +Y +++ AV ES Q T + +P++L+ T + +
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 614 WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
W E+ V Y+ V+ L GE + + R T A +T L PG Y + AV +
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
Query: 672 SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730
++S P T T+LD+P +L +++++ + WT I YR+T G +
Sbjct: 983 GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788
V + Y L +L+P +EY +S+ A +G Q+S ++T FT +P S + + + VT +
Sbjct: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
Query: 789 SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845
++ ITW+ PA R+ L P E EV+ D+ V+ GL P EY+ + V
Sbjct: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
Query: 846 AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901
G PIV + T + PP ++ + +N + VSW YR++ PT
Sbjct: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
Query: 902 QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961
Q G VV + T L+P EY +S+ +V+ +ES I + + DL
Sbjct: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
Query: 962 TNITPTEALLQWKAPVGE--VENYVIVLTHFAVAGETI-----LVDGVSEEFRLVDLLPS 1014
+IT + L+W P+ + Y I + AGE I VD + + L P
Sbjct: 1276 VDITDSSIGLRW-TPLNSSTIIGYRITV---VAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
Query: 1015 THYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRA-EIENYV 1072
Y ++ NG ++ T T T + PP +L + + + ++W PP + ++ N++
Sbjct: 1332 IDYDISVITLINGGESAPTTLTQ-QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1390
Query: 1073 LTYKSTDGSR--KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD---------------- 1114
+ Y EL + D + L LL T+Y V + + +
Sbjct: 1391 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
Query: 1115 ----TTWSSITSTAFT----------TGGRVFPHP--------QDCAQHLMNGDTLSGVY 1152
+S IT+ +FT TG R+ HP +D H N TL+ +
Sbjct: 1451 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
Query: 1153 P 1153
P
Sbjct: 1511 P 1511
Score = 166 bits (421), Expect = 1e-40
Identities = 159/647 (24%), Positives = 273/647 (42%), Gaps = 42/647 (6%)
Query: 506 GPTQILVRDVSDTVAF--VEWIPPR-AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562
GP ++ + + ++W P+ + + +L++ G + L+ Y+++
Sbjct: 610 GPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIK 669
Query: 563 ALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPKNLRVGSRTATSLDLEWDNSEA 619
L+PG YE + +++ + FTT N G T S + S
Sbjct: 670 GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
Query: 620 EVQEYKVVYS------TLAGEQYHEVLVPRGIGP--------TTRATLTDLVPGTEYGVG 665
E+ V S T++G + L G P T + DL+PG +Y V
Sbjct: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
Query: 666 ISAVM-NSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS- 723
+ + + +QS+ + + T D+P D V +TSI + W++ PI YRI ++PS
Sbjct: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
Query: 724 SGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISH---- 779
G ++E+ +P+ S TL+DL+PG +Y I++ A Q+S + T P S
Sbjct: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
Query: 780 ---LHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQP 836
L F VT V I W+ P ++ P + E + + A + GL P
Sbjct: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
Query: 837 ATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896
Y + AV S+P+ TT +D P ++ N T +V+V W+PP A YR+
Sbjct: 970 GVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRL 1029
Query: 897 SYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMD-- 954
+ T+ G+ V +V+++ + L PA+EY +SL +++G +ES + T V T +
Sbjct: 1030 TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK-ATGVFTTLQPG 1088
Query: 955 NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETIL-VDGVSEEFRLVDLLP 1013
+ + T +T T ++ W P + + V + GE V S + L P
Sbjct: 1089 SSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRP--SQGGEAPREVTSDSGSIVVSGLTP 1145
Query: 1014 STHYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSAL-ISWQ-PPRAEIEN 1070
Y T+ +G I T L PP NL L +SW+ +I
Sbjct: 1146 GVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG 1205
Query: 1071 YVLTYKSTDGSR---KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
Y +T T+G + E +V A+ + + L +Y V + +D
Sbjct: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
Score = 131 bits (330), Expect = 4e-30
Identities = 77/296 (26%), Positives = 136/296 (45%), Gaps = 3/296 (1%)
Query: 320 GPDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWS 378
G +A+ P DL+ ++ S+ +W P + +T Y + P G + + D S
Sbjct: 1807 GTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSS 1866
Query: 379 GVTITELEPGLTYNISVYAVISNILSLPITAKVAT--HLSTPQGLQFKTITETTVEVQWE 436
V ++ L Y +SVYA+ + S P V T ++S P+ + TETT+ + W
Sbjct: 1867 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1926
Query: 437 PFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
+ + G+++ +P N + + + DV S+ TGL+PG +Y + + L + ARS P
Sbjct: 1927 TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1986
Query: 497 SASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPL 556
ST ID P+ + + V W PPRA++ ++KY G R +P +
Sbjct: 1987 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 2046
Query: 557 SQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
++ ++ L PG+ Y + V A++ +S+ + T P G T + L
Sbjct: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQL 2102
Score = 48.9 bits (115), Expect = 3e-05
Identities = 57/225 (25%), Positives = 84/225 (37%), Gaps = 57/225 (25%)
Query: 324 SAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTI 382
+A+ P +LR + S+ + W P A +T Y+I Y+ ++ R + TI
Sbjct: 1992 TAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
Query: 383 TELEPGLTYNISVYAVISNILSLPITAKVATHLSTP----------QGLQF--------- 423
T LEPG Y I V A+ +N S P+ + T TP G+Q
Sbjct: 2052 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 2111
Query: 424 -------------KTITETTVE----------------------VQWEPFSFSFDGWEIS 448
+T TT + W PF + + + IS
Sbjct: 2112 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE-YIIS 2170
Query: 449 FIPKN-NEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQAR 492
P +E + +VP TS TGL G Y + V ALK+Q R
Sbjct: 2171 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2215
>gi|223029463 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 216 bits (550), Expect = 1e-55
Identities = 107/225 (47%), Positives = 138/225 (61%), Gaps = 14/225 (6%)
Query: 1127 TGGRVFPHPQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNG 1186
TG R P+DC L++G GVY +F QVYCDM TDGGGW VFQRR++G
Sbjct: 237 TGSR----PRDCLDVLLSGQQDDGVYSVFPT-HYPAGFQVYCDMRTDGGGWTVFQRREDG 291
Query: 1187 QTDFFRKWADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQE-AAFASYDR-- 1243
+FFR W YR GFG + E WLGL IH +T+Q YEL VD+ D + A+A Y
Sbjct: 292 SVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFG 351
Query: 1244 ---FSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWY 1300
FSV+ + Y L + Y+GTAGDSL H G F+T+DRD+D + NCA Y+GAWWY
Sbjct: 352 VGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWY 411
Query: 1301 KNCHRTNLNGKYGESRH---SQGINWYHWKGHEFSIPFVEMKMRP 1342
+NCH +NLNG+Y H + G+ W W G ++S+ F EMK+RP
Sbjct: 412 RNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRP 456
>gi|223029461 fibrinogen C domain containing 1 [Homo sapiens]
Length = 461
Score = 216 bits (550), Expect = 1e-55
Identities = 107/225 (47%), Positives = 138/225 (61%), Gaps = 14/225 (6%)
Query: 1127 TGGRVFPHPQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNG 1186
TG R P+DC L++G GVY +F QVYCDM TDGGGW VFQRR++G
Sbjct: 237 TGSR----PRDCLDVLLSGQQDDGVYSVFPT-HYPAGFQVYCDMRTDGGGWTVFQRREDG 291
Query: 1187 QTDFFRKWADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQE-AAFASYDR-- 1243
+FFR W YR GFG + E WLGL IH +T+Q YEL VD+ D + A+A Y
Sbjct: 292 SVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFG 351
Query: 1244 ---FSVEDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWY 1300
FSV+ + Y L + Y+GTAGDSL H G F+T+DRD+D + NCA Y+GAWWY
Sbjct: 352 VGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWY 411
Query: 1301 KNCHRTNLNGKYGESRH---SQGINWYHWKGHEFSIPFVEMKMRP 1342
+NCH +NLNG+Y H + G+ W W G ++S+ F EMK+RP
Sbjct: 412 RNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRP 456
>gi|8051586 ficolin 2 isoform b precursor [Homo sapiens]
Length = 275
Score = 212 bits (540), Expect = 2e-54
Identities = 106/213 (49%), Positives = 138/213 (64%), Gaps = 7/213 (3%)
Query: 1135 PQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKW 1194
P+ C L G LSG + I+L + L V CDM TDGGGW VFQRR +G DF+R W
Sbjct: 64 PRTCKDLLDRGHFLSGWHTIYLPD--CRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDW 121
Query: 1195 ADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQE-AAFASYDRFSVEDSRNLY 1253
A Y+ GFG+ EFWLG DNIH +T+QG ELRVD+ D ++ FA Y F V D Y
Sbjct: 122 ATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKY 181
Query: 1254 KLRIGSY-NGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKY 1312
L +G++ G+AGDSL++H + FST+D+DND+ NCA+ ++GAWWYKNCH +NLNG+Y
Sbjct: 182 NLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRY 241
Query: 1313 GESRH---SQGINWYHWKGHEFSIPFVEMKMRP 1342
H + GINW KG+ +S EMK+RP
Sbjct: 242 LRGTHGSFANGINWKSGKGYNYSYKVSEMKVRP 274
>gi|61744445 ficolin 2 isoform a precursor [Homo sapiens]
Length = 313
Score = 212 bits (540), Expect = 2e-54
Identities = 106/213 (49%), Positives = 138/213 (64%), Gaps = 7/213 (3%)
Query: 1135 PQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKW 1194
P+ C L G LSG + I+L + L V CDM TDGGGW VFQRR +G DF+R W
Sbjct: 102 PRTCKDLLDRGHFLSGWHTIYLPD--CRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDW 159
Query: 1195 ADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQE-AAFASYDRFSVEDSRNLY 1253
A Y+ GFG+ EFWLG DNIH +T+QG ELRVD+ D ++ FA Y F V D Y
Sbjct: 160 ATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKY 219
Query: 1254 KLRIGSY-NGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKY 1312
L +G++ G+AGDSL++H + FST+D+DND+ NCA+ ++GAWWYKNCH +NLNG+Y
Sbjct: 220 NLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRY 279
Query: 1313 GESRH---SQGINWYHWKGHEFSIPFVEMKMRP 1342
H + GINW KG+ +S EMK+RP
Sbjct: 280 LRGTHGSFANGINWKSGKGYNYSYKVSEMKVRP 312
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 210 bits (535), Expect = 7e-54
Identities = 216/833 (25%), Positives = 350/833 (42%), Gaps = 58/833 (6%)
Query: 323 CSAVAPPEDLR------VAGISDRSIELEWDGPM-AVTEYVISYQPTALGGLQLQQRVPG 375
C++V P DL ++ + RS + W P +V Y + Y P + GG + + V
Sbjct: 212 CNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS-GGKRQEFYVSR 270
Query: 376 DWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQW 435
+ + +L+P Y ++VY+V+ + S P+ T L + TT+ VQW
Sbjct: 271 METSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW 330
Query: 436 EPFSFSFDGWEISFIP-KNNEGGVIAQV--PSDVTSFNQTGLKPGEEYIVNVVA-LKEQA 491
+P G+ +S+ P K+ E +V V T L P EY V V A L +
Sbjct: 331 QPVG-GATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLT 389
Query: 492 RSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFR 551
P T V+ + P + +RDV+ + V W P KV +++Y E
Sbjct: 390 SEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKT--PEEDVKEVE 447
Query: 552 LQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTE-IDAPKNLRVGSRTATSL 610
+ + S++ L + Y VSVSAV ES T Q TT + AP NL++ T+
Sbjct: 448 VDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGF 507
Query: 611 DLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAV- 669
WD+ ++V Y++ ++ E ++ G +L P T Y V I+A+
Sbjct: 508 RGTWDHGASDVSLYRITWAPFGSSDKMETILN---GDENTLVFENLNPNTIYEVSITAIY 564
Query: 670 ---------MNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF 720
+ S++++P + + PR+L V ++ S+++ W ASG + YRIT+
Sbjct: 565 PDESESDDLIGSERTLP-ILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITY 623
Query: 721 TPSSGIASE--VTVPKDRTSYTLTDLEPGAEYIISVTA-----ERGRQQSLESTVDAFTG 773
PS+G +E T+ + S L L+P Y I+V++ E GR T T
Sbjct: 624 QPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT- 682
Query: 774 FRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMG 833
+ +L ++S++N+ W + L Y+P E + V + +A+L
Sbjct: 683 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRN 738
Query: 834 LQPATEYIVNLVAVH----GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVA 889
LQP T Y V +V V+ G TS+ ++ G+ +++ + N T +S+ V W P
Sbjct: 739 LQPDTSYTVTVVPVYTEGDGGRTSD-TGRTLMRGL--ARNVQVYNPTPNSLDVRWDPAPG 795
Query: 890 SFDYYRVSYRPTQVGR-LDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTL 948
YRV Y P R +S VVP + RL P T Y ++L ++ E
Sbjct: 796 PVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQ 855
Query: 949 VHT-AMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETI----LVDGVS 1003
T P +L T + W G V+ Y I+ + G+ I V G
Sbjct: 856 GRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRII--YSPTVGDPIDEYTTVPGRR 913
Query: 1004 EEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTL-LDPPANLTASEVTRQSALISWQ 1062
L L P T Y T+ A G ++ N T+ L PP N+ S+ +SW
Sbjct: 914 NNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWD 973
Query: 1063 PPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDT 1115
P + + Y + YK + E T L L +T Y V + A D+
Sbjct: 974 PSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDS 1026
Score = 196 bits (498), Expect = 1e-49
Identities = 194/814 (23%), Positives = 348/814 (42%), Gaps = 29/814 (3%)
Query: 316 EGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPT--ALGGLQLQQRV 373
E +G + + P L + + ++ ++W T Y++SY+P + R+
Sbjct: 300 EPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRL 359
Query: 374 PGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVAT-HLSTPQGLQFKTITETTVE 432
+ + +T+L P Y ++V AV+ ++ S P+T + T L PQ L+ + +T +T+
Sbjct: 360 GPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMN 419
Query: 433 VQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQAR 492
V WEP + + + + + +V TS + L Y V+V A+ ++
Sbjct: 420 VFWEPVPGKVRKYIVRYKTPEEDVKEV-EVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE 478
Query: 493 SPPTSASVST-VIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFR 551
SPP +A +T + PT + + +V+ W + V + + G T
Sbjct: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETI- 537
Query: 552 LQPPLSQYSVQALRPGSRYEVSVSAVR-GTNESDSATTQ------FTTEI--DAPKNLRV 602
L + + L P + YEVS++A+ +ESD TT+ P+NL+V
Sbjct: 538 LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQV 597
Query: 603 GSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEY 662
+ T+ SL ++WD + VQ+Y++ Y GE + G L L P T Y
Sbjct: 598 YNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGG--RQNSVVLQKLKPDTPY 655
Query: 663 GVGISAVMNSQQSVPATMNARTE-LDSPRDLMVTASSETSISLIWTKASGPIDHYRITFT 721
+ +S++ + T +T+ L++ R+L V S +++++ W A G Y++ +
Sbjct: 656 TITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYA 715
Query: 722 PSSGIASEVTVPKDRTSYT-LTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPIS-H 779
P++G E+ T+Y L +L+P Y ++V ++ T R ++ +
Sbjct: 716 PAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARN 775
Query: 780 LHFSHVTSSSVNITWSDPSP-PADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPAT 838
+ + T +S+++ W DP+P P + + YSP D + + R L L P T
Sbjct: 776 VQVYNPTPNSLDVRW-DPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDT 834
Query: 839 EYIVNLVAVH--GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896
Y VNLVA++ G P G T P+++ + T +S+ V+W YR+
Sbjct: 835 LYSVNLVALYSDGEGNPSPAQGR-TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRI 893
Query: 897 SYRPTQVGRLDS-SVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTA-MD 954
Y PT +D + VP + L P T Y+I++ +V + + T +
Sbjct: 894 IYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLL 953
Query: 955 NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPS 1014
P ++ ++ T + W V Y IV G + L +L PS
Sbjct: 954 PPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPS 1013
Query: 1015 THYTATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLT 1074
T Y +YA S ++ +TL +L ++ + + W P RA +Y L
Sbjct: 1014 TTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLK 1072
Query: 1075 YKSTDGSR-KELIVDAEDTWIRLEGLLENTDYTV 1107
DG+R +E+ V +T GL +TDY V
Sbjct: 1073 LSPADGTRGQEITVRGSETSHCFTGLSPDTDYGV 1106
Score = 178 bits (452), Expect = 3e-44
Identities = 182/762 (23%), Positives = 302/762 (39%), Gaps = 38/762 (4%)
Query: 391 YNISVYAVISNI-----LSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGW 445
YN++ + +S I ++L + K L P L T + V W P S S D +
Sbjct: 192 YNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRY 251
Query: 446 EISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVID 505
++ + P + V TS LKP EY+VNV ++ E S P + T+
Sbjct: 252 KVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPV 311
Query: 506 GPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGR-TTFRLQPPLSQYSVQAL 564
+ + DV T V+W P +IL + E R RL P ++ + L
Sbjct: 312 PVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDL 371
Query: 565 RPGSRYEVSVSAVRGTNESDSATT-QFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQE 623
P + Y V+V AV S+ T + T + P++L++ T +++++ W+ +V++
Sbjct: 372 VPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRK 431
Query: 624 YKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNAR 683
Y V Y T E EV V R T +L DL T Y V +SAV + +S P T
Sbjct: 432 YIVRYKT-PEEDVKEVEVDRS---ETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQET 487
Query: 684 TE-LDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTP-SSGIASEVTVPKDRTSYTL 741
T + +P +L +T + W + + YRIT+ P S E + D +
Sbjct: 488 TRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVF 547
Query: 742 TDLEPGAEYIISVTA---ERGRQQSL---ESTVDAFTGFRPIS---HLHFSHVTSSSVNI 792
+L P Y +S+TA + L E T+ T P S +L + TS+S+ +
Sbjct: 548 ENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTV 607
Query: 793 TWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVT 852
W S + + Y P E ++ + VL L+P T Y + + +++
Sbjct: 608 KWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGE 667
Query: 853 SEPIVG-SITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVV 911
+ G T ++ +++ + + + ++ V W + Y++ Y P G + +
Sbjct: 668 GGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPI 727
Query: 912 PNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPV-DLIATNITPTEAL 970
P + L P T Y +++ V + R T M ++ N TP
Sbjct: 728 PGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLD 787
Query: 971 LQWKAPVGEVENYVIVLTHF--AVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPL 1028
++W G V Y +V + E+I+V G + L L+P T Y+ + A
Sbjct: 788 VRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDG 847
Query: 1029 TSGTISTNFSTL-LDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIV 1087
TL P NL T S ++W ++ Y + Y T G
Sbjct: 848 EGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVG------- 900
Query: 1088 DAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGG 1129
D D + + G N V+LQ Q T IT A G
Sbjct: 901 DPIDEYTTVPGRRNN----VILQPLQPDTPYKITVIAVYEDG 938
Score = 169 bits (427), Expect = 2e-41
Identities = 171/651 (26%), Positives = 268/651 (41%), Gaps = 36/651 (5%)
Query: 326 VAPPEDLRVAGISDRSIELEWD-GPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITE 384
V P +L++ ++ WD G V+ Y I++ P +++ + GD + +
Sbjct: 491 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSD-KMETILNGDENTLVFEN 549
Query: 385 LEPGLTYNISVYAV----------ISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQ 434
L P Y +S+ A+ I + +LPI A S P+ LQ T ++ V+
Sbjct: 550 LNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPK-SGPRNLQVYNATSNSLTVK 608
Query: 435 WEPFSFSFDGWEISFIPKNNEGGV-IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARS 493
W+P S + I++ P EG + S LKP Y + V +L
Sbjct: 609 WDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEG 668
Query: 494 PP-TSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
T + ++ + V D S + V W L Y G G
Sbjct: 669 GRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG--GPEELVP 726
Query: 553 QPPLSQYSV-QALRPGSRYEVSVSAVRGTNESDSATTQFTTEI---DAPKNLRVGSRTAT 608
P + Y++ + L+P + Y V+V V E D T T +N++V + T
Sbjct: 727 IPGNTNYAILRNLQPDTSYTVTVVPVY--TEGDGGRTSDTGRTLMRGLARNVQVYNPTPN 784
Query: 609 SLDLEWDNSEAEVQEYKVVYSTLAGEQYHE-VLVPRGIGPTTRATLTDLVPGTEYGVGIS 667
SLD+ WD + V +Y+VVYS + G + E ++VP G T L L+P T Y V +
Sbjct: 785 SLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVP---GNTRMVHLERLIPDTLYSVNLV 841
Query: 668 AVMNSQQSVPATMNART-ELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSG- 725
A+ + + P+ RT PR+L V + S+S+ W A GP+ YRI ++P+ G
Sbjct: 842 ALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD 901
Query: 726 -IASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFT-GFRPISHLHFS 783
I TVP R + L L+P Y I+V A T + T G P ++H S
Sbjct: 902 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHIS 961
Query: 784 HVTSSSVNITWSDPSP-PADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIV 842
+ ++W DPSP P + Y P E M + T L L P+T Y V
Sbjct: 962 DEWYTRFRVSW-DPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSY--TLHNLNPSTTYDV 1018
Query: 843 NLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ 902
N+ A + + S P+ TT D+ + D+ V WSP A+ YR+ P
Sbjct: 1019 NVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATS-YRLKLSPAD 1077
Query: 903 VGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAM 953
R V + T T L+P T+Y +++ E + HT +
Sbjct: 1078 GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTV 1128
Score = 116 bits (291), Expect = 1e-25
Identities = 86/280 (30%), Positives = 130/280 (46%), Gaps = 14/280 (5%)
Query: 864 IDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRL 923
++ P ++ IS T S VSW+PP S D Y+V Y P G+ V T + L
Sbjct: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280
Query: 924 NPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNI---TPTEALLQWKAPVGEV 980
P TEY +++ SV E SE L T PV +++ NI PT +QW+ PVG
Sbjct: 281 KPETEYVVNVYSVVEDEYSE---PLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ-PVGGA 336
Query: 981 ENYVI----VLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTN 1036
Y++ V + + + + +L DL+P+T Y T+ A LTS ++
Sbjct: 337 TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVR 396
Query: 1037 FSTL-LDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIR 1095
TL L P +L +VT + + W+P ++ Y++ YK+ + KE+ VD +T
Sbjct: 397 EVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTS 456
Query: 1096 LEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFPHP 1135
L+ L T YTV + A D S + TT R P P
Sbjct: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETT--RPVPAP 494
Score = 110 bits (276), Expect = 7e-24
Identities = 102/387 (26%), Positives = 170/387 (43%), Gaps = 14/387 (3%)
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSV 790
T P D +Y + D E + + +T +L ++V S+L S T S
Sbjct: 184 TDPDDTHAYNVADFESLSRIVDDLTI------NLCNSVKGPGDLEAPSNLVISERTHRSF 237
Query: 791 NITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT 850
++W+ PS DR + Y P + E + + VL L+P TEY+VN+ +V
Sbjct: 238 RVSWTPPSDSVDRYKVEYYPVSGGKRQ-EFYVSRMETSTVLKDLKPETEYVVNVYSVVED 296
Query: 851 VTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRP---TQVGRLD 907
SEP+ G+ T P + I +V ++ V W PV Y +SY+P T+ R
Sbjct: 297 EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ-PVGGATGYILSYKPVKDTEPTRPK 355
Query: 908 SSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTL-VHTAMDNPVDLIATNITP 966
+ TV + +T L P TEY +++ +V SE + V + P DL ++T
Sbjct: 356 EVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTH 415
Query: 967 TEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNG 1026
+ + W+ G+V Y++ + + VD L DL T YT ++ A +
Sbjct: 416 STMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHD 475
Query: 1027 PLTSGTISTNFSTLLDP-PANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRK-E 1084
S ++ +T P P NL +EVT + +W +++ Y +T+ S K E
Sbjct: 476 EGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKME 535
Query: 1085 LIVDAEDTWIRLEGLLENTDYTVLLQA 1111
I++ ++ + E L NT Y V + A
Sbjct: 536 TILNGDENTLVFENLNPNTIYEVSITA 562
Score = 100 bits (250), Expect = 7e-21
Identities = 105/452 (23%), Positives = 180/452 (39%), Gaps = 12/452 (2%)
Query: 331 DLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGL 389
+LRV S ++ + WD +Y + Y P A GG + +PG+ + + L+P
Sbjct: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAA-GGPEELVPIPGNTNYAILRNLQPDT 743
Query: 390 TYNISVYAVISNILSLPITAKVATHL-STPQGLQFKTITETTVEVQWEPFSFSFDGWEIS 448
+Y ++V V + + T + + +Q T +++V+W+P + +
Sbjct: 744 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803
Query: 449 FIPKNN-EGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVI-DG 506
+ P + VP + + L P Y VN+VAL P+ A T+ G
Sbjct: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 863
Query: 507 PTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRP 566
P + V + V W V + Y G+ + + +Q L+P
Sbjct: 864 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQP 923
Query: 567 GSRYEVSVSAVRGTNESDSATTQF-TTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYK 625
+ Y+++V AV + T T + P+N+ + T + WD S + V YK
Sbjct: 924 DTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYK 983
Query: 626 VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTE 685
+VY + + E V G T TL +L P T Y V + A +S SVP T T
Sbjct: 984 IVYKPVGSNEPMEAFV----GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 1039
Query: 686 LDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGI-ASEVTVPKDRTSYTLTDL 744
+ DL + + W+ YR+ +P+ G E+TV TS+ T L
Sbjct: 1040 YLNVTDLKTYQIGWDTFCVKWSPHRAATS-YRLKLSPADGTRGQEITVRGSETSHCFTGL 1098
Query: 745 EPGAEYIISVTAERGRQQSLESTVDAFTGFRP 776
P +Y ++V + + +V T +P
Sbjct: 1099 SPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 1130
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 210 bits (535), Expect = 7e-54
Identities = 216/833 (25%), Positives = 350/833 (42%), Gaps = 58/833 (6%)
Query: 323 CSAVAPPEDLR------VAGISDRSIELEWDGPM-AVTEYVISYQPTALGGLQLQQRVPG 375
C++V P DL ++ + RS + W P +V Y + Y P + GG + + V
Sbjct: 1376 CNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVS-GGKRQEFYVSR 1434
Query: 376 DWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQW 435
+ + +L+P Y ++VY+V+ + S P+ T L + TT+ VQW
Sbjct: 1435 METSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW 1494
Query: 436 EPFSFSFDGWEISFIP-KNNEGGVIAQV--PSDVTSFNQTGLKPGEEYIVNVVA-LKEQA 491
+P G+ +S+ P K+ E +V V T L P EY V V A L +
Sbjct: 1495 QPVG-GATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLT 1553
Query: 492 RSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFR 551
P T V+ + P + +RDV+ + V W P KV +++Y E
Sbjct: 1554 SEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKT--PEEDVKEVE 1611
Query: 552 LQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTE-IDAPKNLRVGSRTATSL 610
+ + S++ L + Y VSVSAV ES T Q TT + AP NL++ T+
Sbjct: 1612 VDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGF 1671
Query: 611 DLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAV- 669
WD+ ++V Y++ ++ E ++ G +L P T Y V I+A+
Sbjct: 1672 RGTWDHGASDVSLYRITWAPFGSSDKMETILN---GDENTLVFENLNPNTIYEVSITAIY 1728
Query: 670 ---------MNSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF 720
+ S++++P + + PR+L V ++ S+++ W ASG + YRIT+
Sbjct: 1729 PDESESDDLIGSERTLP-ILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITY 1787
Query: 721 TPSSGIASE--VTVPKDRTSYTLTDLEPGAEYIISVTA-----ERGRQQSLESTVDAFTG 773
PS+G +E T+ + S L L+P Y I+V++ E GR T T
Sbjct: 1788 QPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT- 1846
Query: 774 FRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMG 833
+ +L ++S++N+ W + L Y+P E + V + +A+L
Sbjct: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRN 1902
Query: 834 LQPATEYIVNLVAVH----GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVA 889
LQP T Y V +V V+ G TS+ ++ G+ +++ + N T +S+ V W P
Sbjct: 1903 LQPDTSYTVTVVPVYTEGDGGRTSD-TGRTLMRGL--ARNVQVYNPTPNSLDVRWDPAPG 1959
Query: 890 SFDYYRVSYRPTQVGR-LDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTL 948
YRV Y P R +S VVP + RL P T Y ++L ++ E
Sbjct: 1960 PVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQ 2019
Query: 949 VHT-AMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETI----LVDGVS 1003
T P +L T + W G V+ Y I+ + G+ I V G
Sbjct: 2020 GRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRII--YSPTVGDPIDEYTTVPGRR 2077
Query: 1004 EEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTL-LDPPANLTASEVTRQSALISWQ 1062
L L P T Y T+ A G ++ N T+ L PP N+ S+ +SW
Sbjct: 2078 NNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWD 2137
Query: 1063 PPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDT 1115
P + + Y + YK + E T L L +T Y V + A D+
Sbjct: 2138 PSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDS 2190
Score = 196 bits (498), Expect = 1e-49
Identities = 203/862 (23%), Positives = 359/862 (41%), Gaps = 75/862 (8%)
Query: 329 PEDLRVAGISDRSIELEWDG-PMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEP 387
P DLRV+ + +++L W G P V +Y+++Y P A GG + V GD + + L+
Sbjct: 817 PRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA-GGETQEVTVRGDTTNTVLQGLKE 875
Query: 388 GLTYNISVYAVISNILSLPITAKVAT--HLSTPQGLQFKTITETTVEVQWEPFSFSFDGW 445
G Y +SV A+ ++ + + T +PQ L K IT+T++ W G+
Sbjct: 876 GTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGY 935
Query: 446 EISFIPKNNEGGVIAQ-VPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVI 504
+S+ ++ + +P D L+P +Y ++V A P + +T +
Sbjct: 936 RVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTEL 995
Query: 505 DGPTQIL-VRDVSDTVAFVEWIPPRAKVDFILLKYGLV---GGEGGRTTFRLQPPLSQYS 560
++ L V + ++ V W P KV + Y +V G G + ++ P ++
Sbjct: 996 SQDSKTLKVDEETENTMRVTWKPAPGKV----VNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
Query: 561 VQALRPGSRYEVSVSAV----RGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDN 616
++ L+P + Y+++V + G S TT + +P+NL+ T +S + W+
Sbjct: 1052 LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTT--ASRFKSPRNLKTSDPTMSSFRVTWEP 1109
Query: 617 SEAEVQEYKVVYSTLAGEQYHEVLVPRGIGP-TTRATLTDLVPGTEYGVGISAVMNSQQS 675
+ EV+ YKV + ++ LV +GP L +L GT Y V + + + +S
Sbjct: 1110 APGEVKGYKVTFHPTGDDRRLGELV---VGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
Query: 676 VPATMNARTELDSPRDLMVTAS-------SETSISLI----WTKASGPIDHYRITFTPSS 724
P T L + + +S +E I L+ W+ ++R + S
Sbjct: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRA---NFRTVRSFIS 1223
Query: 725 GIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDA-FTGFRPISHLHFS 783
I + R L + A R ++ L++ + + G ++ + +
Sbjct: 1224 RIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALN 1283
Query: 784 HVTSSSVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYI 841
+ + T + P A ++ ++ ++ E L +G++ A E
Sbjct: 1284 FIRQQNFR-TQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVE 1342
Query: 842 VNLVAVHGTVTS----------EPIVGSITTGI----------DPPKDITISNVTKDSVM 881
+ ++A T IV +T + + P ++ IS T S
Sbjct: 1343 LKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFR 1402
Query: 882 VSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREE 941
VSW+PP S D Y+V Y P G+ V T + L P TEY +++ SV E
Sbjct: 1403 VSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEY 1462
Query: 942 SERICTLVHTAMDNPVDLIATNI---TPTEALLQWKAPVGEVENYVI----VLTHFAVAG 994
SE L T PV +++ NI PT +QW+ PVG Y++ V
Sbjct: 1463 SE---PLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ-PVGGATGYILSYKPVKDTEPTRP 1518
Query: 995 ETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTL-LDPPANLTASEVT 1053
+ + + + +L DL+P+T Y T+ A LTS ++ TL L P +L +VT
Sbjct: 1519 KEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVT 1578
Query: 1054 RQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQ 1113
+ + W+P ++ Y++ YK+ + KE+ VD +T L+ L T YTV + A
Sbjct: 1579 HSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVH 1638
Query: 1114 DTTWSSITSTAFTTGGRVFPHP 1135
D S + TT R P P
Sbjct: 1639 DEGESPPVTAQETT--RPVPAP 1658
Score = 196 bits (498), Expect = 1e-49
Identities = 194/814 (23%), Positives = 348/814 (42%), Gaps = 29/814 (3%)
Query: 316 EGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPT--ALGGLQLQQRV 373
E +G + + P L + + ++ ++W T Y++SY+P + R+
Sbjct: 1464 EPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRL 1523
Query: 374 PGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVAT-HLSTPQGLQFKTITETTVE 432
+ + +T+L P Y ++V AV+ ++ S P+T + T L PQ L+ + +T +T+
Sbjct: 1524 GPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMN 1583
Query: 433 VQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQAR 492
V WEP + + + + + +V TS + L Y V+V A+ ++
Sbjct: 1584 VFWEPVPGKVRKYIVRYKTPEEDVKEV-EVDRSETSTSLKDLFSQTLYTVSVSAVHDEGE 1642
Query: 493 SPPTSASVST-VIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFR 551
SPP +A +T + PT + + +V+ W + V + + G T
Sbjct: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETI- 1701
Query: 552 LQPPLSQYSVQALRPGSRYEVSVSAVR-GTNESDSATTQ------FTTEI--DAPKNLRV 602
L + + L P + YEVS++A+ +ESD TT+ P+NL+V
Sbjct: 1702 LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQV 1761
Query: 603 GSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEY 662
+ T+ SL ++WD + VQ+Y++ Y GE + G L L P T Y
Sbjct: 1762 YNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGG--RQNSVVLQKLKPDTPY 1819
Query: 663 GVGISAVMNSQQSVPATMNARTE-LDSPRDLMVTASSETSISLIWTKASGPIDHYRITFT 721
+ +S++ + T +T+ L++ R+L V S +++++ W A G Y++ +
Sbjct: 1820 TITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYA 1879
Query: 722 PSSGIASEVTVPKDRTSYT-LTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPIS-H 779
P++G E+ T+Y L +L+P Y ++V ++ T R ++ +
Sbjct: 1880 PAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARN 1939
Query: 780 LHFSHVTSSSVNITWSDPSP-PADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPAT 838
+ + T +S+++ W DP+P P + + YSP D + + R L L P T
Sbjct: 1940 VQVYNPTPNSLDVRW-DPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDT 1998
Query: 839 EYIVNLVAVH--GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896
Y VNLVA++ G P G T P+++ + T +S+ V+W YR+
Sbjct: 1999 LYSVNLVALYSDGEGNPSPAQGR-TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRI 2057
Query: 897 SYRPTQVGRLDS-SVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTA-MD 954
Y PT +D + VP + L P T Y+I++ +V + + T +
Sbjct: 2058 IYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLL 2117
Query: 955 NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPS 1014
P ++ ++ T + W V Y IV G + L +L PS
Sbjct: 2118 PPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPS 2177
Query: 1015 THYTATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLT 1074
T Y +YA S ++ +TL +L ++ + + W P RA +Y L
Sbjct: 2178 TTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLK 2236
Query: 1075 YKSTDGSR-KELIVDAEDTWIRLEGLLENTDYTV 1107
DG+R +E+ V +T GL +TDY V
Sbjct: 2237 LSPADGTRGQEITVRGSETSHCFTGLSPDTDYGV 2270
Score = 178 bits (452), Expect = 3e-44
Identities = 182/762 (23%), Positives = 302/762 (39%), Gaps = 38/762 (4%)
Query: 391 YNISVYAVISNI-----LSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGW 445
YN++ + +S I ++L + K L P L T + V W P S S D +
Sbjct: 1356 YNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRY 1415
Query: 446 EISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVID 505
++ + P + V TS LKP EY+VNV ++ E S P + T+
Sbjct: 1416 KVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPV 1475
Query: 506 GPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGR-TTFRLQPPLSQYSVQAL 564
+ + DV T V+W P +IL + E R RL P ++ + L
Sbjct: 1476 PVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDL 1535
Query: 565 RPGSRYEVSVSAVRGTNESDSATT-QFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQE 623
P + Y V+V AV S+ T + T + P++L++ T +++++ W+ +V++
Sbjct: 1536 VPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRK 1595
Query: 624 YKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNAR 683
Y V Y T E EV V R T +L DL T Y V +SAV + +S P T
Sbjct: 1596 YIVRYKT-PEEDVKEVEVDRS---ETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQET 1651
Query: 684 TE-LDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTP-SSGIASEVTVPKDRTSYTL 741
T + +P +L +T + W + + YRIT+ P S E + D +
Sbjct: 1652 TRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVF 1711
Query: 742 TDLEPGAEYIISVTA---ERGRQQSL---ESTVDAFTGFRPIS---HLHFSHVTSSSVNI 792
+L P Y +S+TA + L E T+ T P S +L + TS+S+ +
Sbjct: 1712 ENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTV 1771
Query: 793 TWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVT 852
W S + + Y P E ++ + VL L+P T Y + + +++
Sbjct: 1772 KWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGE 1831
Query: 853 SEPIVG-SITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVV 911
+ G T ++ +++ + + + ++ V W + Y++ Y P G + +
Sbjct: 1832 GGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPI 1891
Query: 912 PNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPV-DLIATNITPTEAL 970
P + L P T Y +++ V + R T M ++ N TP
Sbjct: 1892 PGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLD 1951
Query: 971 LQWKAPVGEVENYVIVLTHF--AVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPL 1028
++W G V Y +V + E+I+V G + L L+P T Y+ + A
Sbjct: 1952 VRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDG 2011
Query: 1029 TSGTISTNFSTL-LDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIV 1087
TL P NL T S ++W ++ Y + Y T G
Sbjct: 2012 EGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVG------- 2064
Query: 1088 DAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGG 1129
D D + + G N V+LQ Q T IT A G
Sbjct: 2065 DPIDEYTTVPGRRNN----VILQPLQPDTPYKITVIAVYEDG 2102
Score = 174 bits (440), Expect = 7e-43
Identities = 151/577 (26%), Positives = 251/577 (43%), Gaps = 39/577 (6%)
Query: 484 VVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGG 543
+ A+K++A PP S S +V+ W P V + Y G
Sbjct: 624 LAAIKKKAYVPPKDLSFS------------EVTSYGFKTNWSPAGENVFSYHITYKEAAG 671
Query: 544 EGGRTTFRLQPPLSQYSV--QALRPGSRYEVSVSAVRGTNESDSATTQFTTEI--DAPKN 599
+ T P S SV +L+P + Y V+V+A S + TTE AP+N
Sbjct: 672 DDEVTVVE---PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
Query: 600 LRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPG 659
L+V T S + W + V Y+++Y +AG + EV P R TL +L+P
Sbjct: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPN---QRRRTLENLIPD 785
Query: 660 TEYGVGISAVMNSQQSVPATMNARTE--LDSPRDLMVTASSETSISLIWTKASGPIDHYR 717
T+Y V + S P T NA TE +PRDL V+ + +++ L W+ A G + Y
Sbjct: 786 TKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYL 845
Query: 718 ITFTP-SSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTA--ERGRQQSLESTVDAFTGF 774
+T+TP + G EVTV D T+ L L+ G +Y +SVTA G +L
Sbjct: 846 VTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEER 905
Query: 775 RPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGL 834
L +T +S+ W+ +++ ++ + E +L H ++ L
Sbjct: 906 GSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENL 965
Query: 835 QPATEYIVNLVAVHGTVTSEPIVGSITTGIDPP-KDITISNVTKDSVMVSWSPPVASFDY 893
QP T+Y +++ A + + EP+ G TT + K + + T++++ V+W P
Sbjct: 966 QPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVN 1025
Query: 894 YRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSV--RGREESERICTLVHT 951
YRV YRP G+ + VP TVT + RL P T Y+I++ + G + + +
Sbjct: 1026 YRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTAS 1085
Query: 952 AMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE-----TILVDGVSEEF 1006
+P +L ++ T + + W+ GEV+ Y + F G+ ++V
Sbjct: 1086 RFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVT---FHPTGDDRRLGELVVGPYDNTV 1142
Query: 1007 RLVDLLPSTHYTATMYAT-NGPLTSGTISTNFSTLLD 1042
L +L T Y ++ +G +S + +TL D
Sbjct: 1143 VLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179
Score = 169 bits (427), Expect = 2e-41
Identities = 171/651 (26%), Positives = 268/651 (41%), Gaps = 36/651 (5%)
Query: 326 VAPPEDLRVAGISDRSIELEWD-GPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITE 384
V P +L++ ++ WD G V+ Y I++ P +++ + GD + +
Sbjct: 1655 VPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSD-KMETILNGDENTLVFEN 1713
Query: 385 LEPGLTYNISVYAV----------ISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQ 434
L P Y +S+ A+ I + +LPI A S P+ LQ T ++ V+
Sbjct: 1714 LNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPK-SGPRNLQVYNATSNSLTVK 1772
Query: 435 WEPFSFSFDGWEISFIPKNNEGGV-IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARS 493
W+P S + I++ P EG + S LKP Y + V +L
Sbjct: 1773 WDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEG 1832
Query: 494 PP-TSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
T + ++ + V D S + V W L Y G G
Sbjct: 1833 GRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG--GPEELVP 1890
Query: 553 QPPLSQYSV-QALRPGSRYEVSVSAVRGTNESDSATTQFTTEI---DAPKNLRVGSRTAT 608
P + Y++ + L+P + Y V+V V E D T T +N++V + T
Sbjct: 1891 IPGNTNYAILRNLQPDTSYTVTVVPVY--TEGDGGRTSDTGRTLMRGLARNVQVYNPTPN 1948
Query: 609 SLDLEWDNSEAEVQEYKVVYSTLAGEQYHE-VLVPRGIGPTTRATLTDLVPGTEYGVGIS 667
SLD+ WD + V +Y+VVYS + G + E ++VP G T L L+P T Y V +
Sbjct: 1949 SLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVP---GNTRMVHLERLIPDTLYSVNLV 2005
Query: 668 AVMNSQQSVPATMNART-ELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSG- 725
A+ + + P+ RT PR+L V + S+S+ W A GP+ YRI ++P+ G
Sbjct: 2006 ALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD 2065
Query: 726 -IASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFT-GFRPISHLHFS 783
I TVP R + L L+P Y I+V A T + T G P ++H S
Sbjct: 2066 PIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHIS 2125
Query: 784 HVTSSSVNITWSDPSP-PADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIV 842
+ ++W DPSP P + Y P E M + T L L P+T Y V
Sbjct: 2126 DEWYTRFRVSW-DPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSY--TLHNLNPSTTYDV 2182
Query: 843 NLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ 902
N+ A + + S P+ TT D+ + D+ V WSP A+ YR+ P
Sbjct: 2183 NVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATS-YRLKLSPAD 2241
Query: 903 VGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAM 953
R V + T T L+P T+Y +++ E + HT +
Sbjct: 2242 GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292
Score = 164 bits (414), Expect = 7e-40
Identities = 195/835 (23%), Positives = 328/835 (39%), Gaps = 66/835 (7%)
Query: 326 VAPPEDLRVAGISDRSIELEWD-GPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITE 384
V PP +L +S + ++L W+ P VT Y + P G Q V + +++ +
Sbjct: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393
Query: 385 LEPGLTYNISVYAVISNILSLPI-----TAKVATHLSTPQGLQFKTI------------- 426
L Y ISV A+ S PI T + + +G+ K
Sbjct: 394 LSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGI 453
Query: 427 -----TETTVEVQWEPFSFSFDGWEISFIPKNNEGGV------IAQVPSDVTSFNQTGLK 475
+EV + F S + +IS + + + +V + + N +
Sbjct: 454 ANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYR 513
Query: 476 PGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFIL 535
G + + P+ S S V IL+ D + AF + D +
Sbjct: 514 GGSTNTGKAMTYVREKIFVPSKGSRSNV--PKVMILITDGKSSDAFRDPAIKLRNSDVEI 571
Query: 536 LKYGLVGGEGGRTTFRLQPPLSQ--YSVQALRPGSRYEVSVS-AVRGTNESDSATTQFTT 592
G+ PP ++V+ R ++ ++ E + A +
Sbjct: 572 FAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKA 631
Query: 593 EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRAT 652
+ PK+L T+ W + V Y + Y AG+ V+ P +T
Sbjct: 632 YVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPAS---STSVV 687
Query: 653 LTDLVPGTEYGVGISAVMNSQQSVPATMNARTE--LDSPRDLMVTASSETSISLIWTKAS 710
L+ L P T Y V ++A S+P TE +PR+L VT + S + WT+A
Sbjct: 688 LSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAP 747
Query: 711 GPIDHYRITFTPSSGIAS-EVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVD 769
G + YRI + P +G S EVT P ++ TL +L P +Y +SV E T +
Sbjct: 748 GRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807
Query: 770 AFTGF---RPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATK 826
A T P L S T+S++ ++WS + ++ Y+P E EV++
Sbjct: 808 AATEEVRGNP-RDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGETQEVTVRGDT 865
Query: 827 RHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGID--PPKDITISNVTKDSVMVSW 884
+ VL GL+ T+Y +++ A++ + + + G TT + P+D+ ++T S+ W
Sbjct: 866 TNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYW 925
Query: 885 SPPVASFDYYRVSYRPTQVGRLDSSV--VPNTVTEFTITRLNPATEYEISLNSVRGREES 942
+ YRVS++ + +D+ +P I L P T+Y IS+ + E
Sbjct: 926 TSAPGMVRGYRVSWK-SLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEG 984
Query: 943 ERICTLVHTAMDNPVDLIATNI-TPTEALLQWKAPVGEVENYVIVLTHFAVAGETIL-VD 1000
E + T + + + T + WK G+V NY +V + + V
Sbjct: 985 EPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVP 1044
Query: 1001 GVSEEFRLVDLLPSTHYTATMYAT----NGPLT--SGTISTNFSTLLDPPANLTASEVTR 1054
L L P T Y T+ G L SGT ++ F + P NL S+ T
Sbjct: 1045 PTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKS----PRNLKTSDPTM 1100
Query: 1055 QSALISWQPPRAEIENYVLTYKSTDGSRK--ELIVDAEDTWIRLEGLLENTDYTV 1107
S ++W+P E++ Y +T+ T R+ EL+V D + LE L T Y V
Sbjct: 1101 SSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKV 1155
Score = 159 bits (402), Expect = 2e-38
Identities = 147/561 (26%), Positives = 240/561 (42%), Gaps = 34/561 (6%)
Query: 418 PQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPG 477
P+ L F +T + W P + + I++ + V P+ TS + LKP
Sbjct: 635 PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPE 694
Query: 478 EEYIVNVVALKEQARSPPTSASVST--VIDGPTQILVRDVSDTVAFVEWI-PPRAKVDFI 534
Y+VNV A E S P + +T V P + V D + + W P + +
Sbjct: 695 TLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYR 754
Query: 535 LLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTE- 593
++ + GGE T P + +++ L P ++YEVSV + T TE
Sbjct: 755 IIYRPVAGGESREVT--TPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEE 812
Query: 594 -IDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRAT 652
P++LRV T +++ L W + +V++Y V Y+ +AG + EV V G TT
Sbjct: 813 VRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVR---GDTTNTV 869
Query: 653 LTDLVPGTEYGVGISAVMNSQQSVPATMNART--ELDSPRDLMVTASSETSISLIWTKAS 710
L L GT+Y + ++A+ S T E SP+DL+ ++TSI WT A
Sbjct: 870 LQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAP 929
Query: 711 GPIDHYRITFTP--SSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTV 768
G + YR+++ E +P+D + +L+P +Y ISV A + T
Sbjct: 930 GMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTG 989
Query: 769 DAFTGFRPISH-LHFSHVTSSSVNITWSDPSPPADRLILN----YSPRDEEEEMMEVSLD 823
DA T S L T +++ +TW PA ++N Y P ++M+ +
Sbjct: 990 DATTELSQDSKTLKVDEETENTMRVTWK----PAPGKVVNYRVVYRPHGRGKQMV-AKVP 1044
Query: 824 ATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTG--IDPPKDITISNVTKDSVM 881
T VL LQP T Y + ++ ++ + GS TT P+++ S+ T S
Sbjct: 1045 PTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFR 1104
Query: 882 VSWSPPVASFDYYRVSYRPT----QVGRLDSSVVPNTVTEFTITRLNPATEYEISL-NSV 936
V+W P Y+V++ PT ++G L NTV + L T Y++++
Sbjct: 1105 VTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTV---VLEELRAGTTYKVNVFGMF 1161
Query: 937 RGREESERICTLVHTAMDNPV 957
G E S + + T D V
Sbjct: 1162 DGGESSPLVGQEMTTLSDTTV 1182
Score = 139 bits (350), Expect = 2e-32
Identities = 188/854 (22%), Positives = 341/854 (39%), Gaps = 81/854 (9%)
Query: 325 AVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPT---ALGGLQLQQRVPGDWSGVT 381
A PP+DL + ++ + W E V SY T A G ++ P + V
Sbjct: 631 AYVPPKDLSFSEVTSYGFKTNWS---PAGENVFSYHITYKEAAGDDEVTVVEPASSTSVV 687
Query: 382 ITELEPGLTYNISVYAVISNILSLPITAKVATH--LSTPQGLQFKTITETTVEVQWEPFS 439
++ L+P Y ++V A + S+P+ + T P+ L+ T + ++ W
Sbjct: 688 LSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAP 747
Query: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQT--GLKPGEEYIVNVVALKEQARSPPTS 497
+ I + P GG +V + +T L P +Y V+V+ P +
Sbjct: 748 GRVLRYRIIYRPV--AGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLT 805
Query: 498 ASVST--VIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKY-GLVGGEGGRTTFRLQP 554
+ +T V P + V D + + + W KV L+ Y + GGE T R
Sbjct: 806 GNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVR--G 863
Query: 555 PLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTT--EIDAPKNLRVGSRTATSLDL 612
+ +Q L+ G++Y +SV+A+ + D+ + TT E +P++L T TS+
Sbjct: 864 DTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGA 923
Query: 613 EWDNSEAEVQEYKVVYSTLAGE-QYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
W ++ V+ Y+V + +L + E +P + +L P T+Y + + A +
Sbjct: 924 YWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPE---DAIHTMIENLQPETKYRISVFATYS 980
Query: 672 SQQSVPATMNARTEL-DSPRDLMVTASSETSISLIWTKASGPIDHYRITFTP-SSGIASE 729
S + P T +A TEL + L V +E ++ + W A G + +YR+ + P G
Sbjct: 981 SGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMV 1040
Query: 730 VTVPKDRTSYTLTDLEPGAEYIISVTA--ERGRQQSLESTVDAFTGFRPISHLHFSHVTS 787
VP TS L L+P Y I+V + G + + + + F+ +L S T
Sbjct: 1041 AKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTM 1100
Query: 788 SSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAV 847
SS +TW + + P ++ + E+ + VL L+ T Y VN+ +
Sbjct: 1101 SSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGM 1160
Query: 848 HGTVTSEPIVGSITTGIDPPKDITI--------SNVTKDSVMV---SWSPPVASF----- 891
S P+VG T + + I + D V++ SWS A+F
Sbjct: 1161 FDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRS 1220
Query: 892 ------DYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRG------- 938
+ + + + Q+ S P T + R + ++ +G
Sbjct: 1221 FISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGM 1280
Query: 939 -----REESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVA 993
R+++ R M I IT ++ +AP ++++ + L FA+
Sbjct: 1281 ALNFIRQQNFR----TQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL--FAIG 1334
Query: 994 GETILVDGVSEEFRLVDLLP-STH-YTATMYATNGPLTSGTISTNFSTLLDPPANLTA-- 1049
+ + E +++ P TH Y + + + ++ N + P +L A
Sbjct: 1335 ----IKNADEVELKMIATDPDDTHAYNVADFESLSRIVD-DLTINLCNSVKGPGDLEAPS 1389
Query: 1050 ----SEVTRQSALISWQPPRAEIENY-VLTYKSTDGSRKELIVDAEDTWIRLEGLLENTD 1104
SE T +S +SW PP ++ Y V Y + G R+E V +T L+ L T+
Sbjct: 1390 NLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETE 1449
Query: 1105 YTVLLQAAQDTTWS 1118
Y V + + + +S
Sbjct: 1450 YVVNVYSVVEDEYS 1463
Score = 110 bits (276), Expect = 7e-24
Identities = 102/387 (26%), Positives = 170/387 (43%), Gaps = 14/387 (3%)
Query: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSV 790
T P D +Y + D E + + +T +L ++V S+L S T S
Sbjct: 1348 TDPDDTHAYNVADFESLSRIVDDLTI------NLCNSVKGPGDLEAPSNLVISERTHRSF 1401
Query: 791 NITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT 850
++W+ PS DR + Y P + E + + VL L+P TEY+VN+ +V
Sbjct: 1402 RVSWTPPSDSVDRYKVEYYPVSGGKRQ-EFYVSRMETSTVLKDLKPETEYVVNVYSVVED 1460
Query: 851 VTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRP---TQVGRLD 907
SEP+ G+ T P + I +V ++ V W PV Y +SY+P T+ R
Sbjct: 1461 EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ-PVGGATGYILSYKPVKDTEPTRPK 1519
Query: 908 SSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTL-VHTAMDNPVDLIATNITP 966
+ TV + +T L P TEY +++ +V SE + V + P DL ++T
Sbjct: 1520 EVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTH 1579
Query: 967 TEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNG 1026
+ + W+ G+V Y++ + + VD L DL T YT ++ A +
Sbjct: 1580 STMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHD 1639
Query: 1027 PLTSGTISTNFSTLLDP-PANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRK-E 1084
S ++ +T P P NL +EVT + +W +++ Y +T+ S K E
Sbjct: 1640 EGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKME 1699
Query: 1085 LIVDAEDTWIRLEGLLENTDYTVLLQA 1111
I++ ++ + E L NT Y V + A
Sbjct: 1700 TILNGDENTLVFENLNPNTIYEVSITA 1726
Score = 100 bits (250), Expect = 7e-21
Identities = 105/452 (23%), Positives = 180/452 (39%), Gaps = 12/452 (2%)
Query: 331 DLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGL 389
+LRV S ++ + WD +Y + Y P A GG + +PG+ + + L+P
Sbjct: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAA-GGPEELVPIPGNTNYAILRNLQPDT 1907
Query: 390 TYNISVYAVISNILSLPITAKVATHL-STPQGLQFKTITETTVEVQWEPFSFSFDGWEIS 448
+Y ++V V + + T + + +Q T +++V+W+P + +
Sbjct: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967
Query: 449 FIPKNN-EGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVI-DG 506
+ P + VP + + L P Y VN+VAL P+ A T+ G
Sbjct: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027
Query: 507 PTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRP 566
P + V + V W V + Y G+ + + +Q L+P
Sbjct: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQP 2087
Query: 567 GSRYEVSVSAVRGTNESDSATTQF-TTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYK 625
+ Y+++V AV + T T + P+N+ + T + WD S + V YK
Sbjct: 2088 DTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYK 2147
Query: 626 VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTE 685
+VY + + E V G T TL +L P T Y V + A +S SVP T T
Sbjct: 2148 IVYKPVGSNEPMEAFV----GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203
Query: 686 LDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGI-ASEVTVPKDRTSYTLTDL 744
+ DL + + W+ YR+ +P+ G E+TV TS+ T L
Sbjct: 2204 YLNVTDLKTYQIGWDTFCVKWSPHRAATS-YRLKLSPADGTRGQEITVRGSETSHCFTGL 2262
Query: 745 EPGAEYIISVTAERGRQQSLESTVDAFTGFRP 776
P +Y ++V + + +V T +P
Sbjct: 2263 SPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294
Score = 89.7 bits (221), Expect = 2e-17
Identities = 134/594 (22%), Positives = 233/594 (39%), Gaps = 72/594 (12%)
Query: 571 EVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYST 630
E+ G +E ++ P NL ++ + L W+ S + V YKV+ +
Sbjct: 311 EIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370
Query: 631 L-AGEQYHEVLVPRGIGP-TTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTE--- 685
+ AG + H + +GP TT ++ DL TEY + +SA+ S P ++ +T+
Sbjct: 371 MTAGSRQHAL----SVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMK 426
Query: 686 --------LDSPRDLMVTASSETSISL---IWTKASGPIDHYRITFTPSSGIASEVTVPK 734
+D D++ SI + + +A + +P+ S V +
Sbjct: 427 VQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSR 486
Query: 735 D-RTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRP----ISHLHFSHVTSSS 789
D T +TL + I ++ R S +T A T R S S+V
Sbjct: 487 DPHTEFTLKKFTKVEDIIEAINTFPYRGGS-TNTGKAMTYVREKIFVPSKGSRSNVPKVM 545
Query: 790 VNITWSDPS----PPADRLILNYSPRDEEEEMMEVSL-DATKRHAVLMGLQPATEYIVNL 844
+ IT S PA +L R+ + E+ V + DA + + PA ++ +
Sbjct: 546 ILITDGKSSDAFRDPAIKL------RNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTV 599
Query: 845 VAVHG-TVTSEPIVGSITTGID------------PPKDITISNVTKDSVMVSWSPPVASF 891
S + SI I+ PPKD++ S VT +WSP +
Sbjct: 600 EDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENV 659
Query: 892 DYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNS---------VRGREES 942
Y ++Y+ + V P + T ++ L P T Y +++ + + G E +
Sbjct: 660 FSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT 719
Query: 943 ERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGV 1002
E + P +L T+ T + W G V Y I+ A GE+ V
Sbjct: 720 EEV-------KGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVA-GGESREVTTP 771
Query: 1003 SEEFR--LVDLLPSTHYTATMYAT--NGPLTSGTISTNFSTLLDPPANLTASEVTRQSAL 1058
+ R L +L+P T Y ++ +GP T T + + P +L S+ T +
Sbjct: 772 PNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMK 831
Query: 1059 ISWQPPRAEIENYVLTYKS-TDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111
+SW +++ Y++TY G +E+ V + T L+GL E T Y + + A
Sbjct: 832 LSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTA 885
Score = 58.5 bits (140), Expect = 4e-08
Identities = 87/411 (21%), Positives = 160/411 (38%), Gaps = 72/411 (17%)
Query: 763 SLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSL 822
S+E+ VD P S L+F + ++V+++W+ P P + P + E +L
Sbjct: 20 SIEAEVD------PPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTK-EFTL 72
Query: 823 DATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSIT--TGIDP---PKDITISNVTK 877
A+ +L L P TEY+V + + S P++G +T TG K + + K
Sbjct: 73 SASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQK 132
Query: 878 DSVMV----------SWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPAT 927
SV SWS +F Y + + V D + T + + + T
Sbjct: 133 CSVSAWTDLVFLVDGSWSVGRNNFKYI-LDFIAALVSAFD---IGEEKTRVGVVQYSSDT 188
Query: 928 EYEISLNSVRGREESERICTLV-----HTAMDNPVDLIATN------------------I 964
E +LN R+E + +T + +D + N I
Sbjct: 189 RTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIII 248
Query: 965 TPTEALLQWKAPVGEVENYVIVLTHFAV-AGETILVDGVSEEFRLVDLLPSTHYTATMYA 1023
T ++ + + P E+ N + + + A + + ++ L + ++ A +
Sbjct: 249 TDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDI 308
Query: 1024 TN--------------GPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIE 1069
N G L SG +++PP+NL A EV+ + ++W P + +
Sbjct: 309 QNEIISQVCSGVDEQLGELVSG------EEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVT 362
Query: 1070 NY-VLTYKSTDGSRKE-LIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWS 1118
Y V+ T GSR+ L V + T + + L +T+Y + + A + T S
Sbjct: 363 GYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSS 413
Score = 54.3 bits (129), Expect = 8e-07
Identities = 27/87 (31%), Positives = 46/87 (52%)
Query: 856 IVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTV 915
++ SI +DPP D+ + +++V +SW+ PV YR++ PT G + +
Sbjct: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76
Query: 916 TEFTITRLNPATEYEISLNSVRGREES 942
TE ++ L P TEY +++ S EES
Sbjct: 77 TETLLSELVPETEYVVTITSYDEVEES 103
Score = 53.9 bits (128), Expect = 1e-06
Identities = 144/781 (18%), Positives = 274/781 (35%), Gaps = 87/781 (11%)
Query: 407 ITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDV 466
+ + + + P L FK I E TV + W G+ I+ P + + +
Sbjct: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76
Query: 467 TSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWIP 526
T + L P EY+V + + E S P ++ T+ + + T ++
Sbjct: 77 TETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTE--IQKCS 134
Query: 527 PRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPG-SRYEVSVSAVRGTNESDS 585
A D + L G GR F+ V A G + V V ++
Sbjct: 135 VSAWTDLVFLVDG--SWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEF 192
Query: 586 ATTQFTTEIDAPKNLR----VGSRTATSLDLEW-------DNSEAEVQEYKVVYSTLAGE 634
Q+ + ++ G T T +++ +++ A V KV G+
Sbjct: 193 NLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGK 252
Query: 635 QYHEVLVPR-------------GIGPTTRATLTDL--VPGTEYGVGIS---AVMNSQQSV 676
EV +P GI L + P + ++ A+++ Q +
Sbjct: 253 SQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEI 312
Query: 677 PA------------TMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSS 724
+ ++ ++ P +L+ S + L W + P+ Y++ TP +
Sbjct: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
Query: 725 GIASE--VTVPKDRTSYTLTDLEPGAEYIISVTAERG-----------RQQSLESTVDAF 771
+ + ++V T+ ++ DL EY ISV+A +G + Q ++ V+
Sbjct: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECS 432
Query: 772 TGFRPISHLHFSHVTSSSVNI-TWSDPSPPADRLILNY--SPRDEEEEMMEVSLDATKRH 828
G + + F S S+ I + + L+ ++ SP + +++ S D
Sbjct: 433 RGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEF 492
Query: 829 AV--LMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSP 886
+ ++ E I G+ + + + I P + SNV K ++++
Sbjct: 493 TLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGK 552
Query: 887 PVASF------------DYYRVSYRPTQVGRLDSSVVPNTVTE-FTITRLNPATEYEISL 933
+F + + V + L++ P T FT+ + L
Sbjct: 553 SSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFEL 612
Query: 934 NSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGE-VENYVIVLTHFAV 992
+ + + A P DL + +T W +P GE V +Y I T+
Sbjct: 613 TQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNW-SPAGENVFSYHI--TYKEA 669
Query: 993 AGE---TILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFST--LLDPPANL 1047
AG+ T++ S L L P T Y + A S ++ +T + P NL
Sbjct: 670 AGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNL 729
Query: 1048 TASEVTRQSALISWQPPRAEIENYVLTYKS-TDGSRKELIVDAEDTWIRLEGLLENTDYT 1106
++ T S I+W + Y + Y+ G +E+ LE L+ +T Y
Sbjct: 730 KVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYE 789
Query: 1107 V 1107
V
Sbjct: 790 V 790
Score = 39.3 bits (90), Expect = 0.026
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 1028 LTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY-KSTDGSRKELI 1086
L + + ++ +DPP++L + + +SW P I Y +T +TDG KE
Sbjct: 12 LGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFT 71
Query: 1087 VDAEDTWIRLEGLLENTDYTVLL 1109
+ A T L L+ T+Y V +
Sbjct: 72 LSASTTETLLSELVPETEYVVTI 94
>gi|27754778 ficolin 3 isoform 2 precursor [Homo sapiens]
Length = 288
Score = 207 bits (528), Expect = 4e-53
Identities = 103/214 (48%), Positives = 138/214 (64%), Gaps = 7/214 (3%)
Query: 1133 PHPQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFR 1192
P P++C + L G TLSG Y + L + L V+CDM T+GGGW+VFQRRQ+G DFFR
Sbjct: 77 PGPRNCRELLSQGATLSGWYHLCLPE--GRALPVFCDMDTEGGGWLVFQRRQDGSVDFFR 134
Query: 1193 KWADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRD-GQEAAFASYDRFSVEDSRN 1251
W+ YR GFGN E EFWLG +N+H++T QG +ELRV++ D FA Y F + +
Sbjct: 135 SWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVD 194
Query: 1252 LYKLRIGSYN-GTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNG 1310
Y+L +G ++ GTAGDSLS H GRPF+T D D+D + +NCA+ GAWWY +C+R+NLNG
Sbjct: 195 HYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNG 254
Query: 1311 KYGESR---HSQGINWYHWKGHEFSIPFVEMKMR 1341
+Y S H GI+W +G V M +R
Sbjct: 255 RYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR 288
>gi|27754776 ficolin 3 isoform 1 precursor [Homo sapiens]
Length = 299
Score = 206 bits (523), Expect = 2e-52
Identities = 102/212 (48%), Positives = 137/212 (64%), Gaps = 7/212 (3%)
Query: 1135 PQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKW 1194
P++C + L G TLSG Y + L + L V+CDM T+GGGW+VFQRRQ+G DFFR W
Sbjct: 90 PRNCRELLSQGATLSGWYHLCLPE--GRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSW 147
Query: 1195 ADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRD-GQEAAFASYDRFSVEDSRNLY 1253
+ YR GFGN E EFWLG +N+H++T QG +ELRV++ D FA Y F + + Y
Sbjct: 148 SSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHY 207
Query: 1254 KLRIGSYN-GTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKY 1312
+L +G ++ GTAGDSLS H GRPF+T D D+D + +NCA+ GAWWY +C+R+NLNG+Y
Sbjct: 208 QLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRY 267
Query: 1313 GESR---HSQGINWYHWKGHEFSIPFVEMKMR 1341
S H GI+W +G V M +R
Sbjct: 268 AVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR 299
>gi|8051584 ficolin 1 precursor [Homo sapiens]
Length = 326
Score = 204 bits (519), Expect = 5e-52
Identities = 105/213 (49%), Positives = 137/213 (64%), Gaps = 7/213 (3%)
Query: 1135 PQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKW 1194
P++C L G LSG + I+L + L V CDM TDGGGW VFQRR +G DF+R W
Sbjct: 115 PRNCKDLLDRGYFLSGWHTIYLPD--CRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDW 172
Query: 1195 ADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQ-EAAFASYDRFSVEDSRNLY 1253
A Y+ GFG+ EFWLG DNIH +T+QG ELRVD+ D + FA Y F V D Y
Sbjct: 173 AAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKY 232
Query: 1254 KLRIGSY-NGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKY 1312
KL +G++ G+AG+SL+ H FST+D+DNDV+ +NCA ++GAWWY +CH +NLNG Y
Sbjct: 233 KLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLY 292
Query: 1313 GESRH---SQGINWYHWKGHEFSIPFVEMKMRP 1342
H + GINW KG+++S EMK+RP
Sbjct: 293 LMGPHESYANGINWSAAKGYKYSYKVSEMKVRP 325
>gi|23111005 microfibrillar-associated protein 4 [Homo sapiens]
Length = 255
Score = 194 bits (494), Expect = 4e-49
Identities = 102/219 (46%), Positives = 132/219 (60%), Gaps = 15/219 (6%)
Query: 1135 PQDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKW 1194
P DC G GVY I+ +G S + V+CDMTT+GG W VFQ+R NG FFR W
Sbjct: 38 PLDCDDIYAQGYQSDGVYLIYPSGP-SVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGW 96
Query: 1195 ADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQ-EAAFASYDRFSV------- 1246
DY++GFG + E+WLGL N+H +T + +YELRVD+ D + A+A Y FS+
Sbjct: 97 NDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSA 156
Query: 1247 -EDSRNLYKLRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHR 1305
ED L+ G +G AGDSLSYH G+ FST DRD D+ V NCA GA+W+++CH
Sbjct: 157 EEDGYTLFV--AGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHF 214
Query: 1306 TNLNGKYGESRH---SQGINWYHWKGHEFSIPFVEMKMR 1341
NLNG Y H + GINW WKG +S+ EMK+R
Sbjct: 215 ANLNGFYLGGSHLSYANGINWAQWKGFYYSLKRTEMKIR 253
>gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
Length = 493
Score = 191 bits (485), Expect = 4e-48
Identities = 92/213 (43%), Positives = 128/213 (60%), Gaps = 7/213 (3%)
Query: 1136 QDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWA 1195
+DC Q L +G S +Y + ++ +QV+CD D GGW V QRR +G +FFR W
Sbjct: 276 RDCLQALEDGHDTSSIY-LVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWE 334
Query: 1196 DYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRD-GQEAAFASYDRFSVEDSRNLYK 1254
Y+ GFGN++ E+WLGL+NI+ +T+QG Y+L V M D FA Y F +E YK
Sbjct: 335 TYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTMEDWSGRKVFAEYASFRLEPESEYYK 394
Query: 1255 LRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLN----- 1309
LR+G Y+G AGDS ++H G+ F+T DRD+DV NCA KG WWY C +NLN
Sbjct: 395 LRLGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYR 454
Query: 1310 GKYGESRHSQGINWYHWKGHEFSIPFVEMKMRP 1342
G + SR+ G+ W ++G +S+ V M +RP
Sbjct: 455 GGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRP 487
>gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]
Length = 491
Score = 187 bits (475), Expect = 6e-47
Identities = 83/213 (38%), Positives = 132/213 (61%), Gaps = 7/213 (3%)
Query: 1136 QDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWA 1195
+DC Q G ++SG+Y I + +Q++C+ + D GGW V Q+R +G +FFR W
Sbjct: 278 KDCQQAKEAGHSVSGIYMIKPENS-NGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWE 336
Query: 1196 DYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRD-GQEAAFASYDRFSVEDSRNLYK 1254
+Y+ GFGN++ E+WLGL+NI+ +++Q Y+L +++ D + +A Y F +E Y+
Sbjct: 337 NYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYR 396
Query: 1255 LRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLN----- 1309
LR+G+Y G AGDS+ +H G+ F+T DRD D+ NCA +KG WWY C +NLN
Sbjct: 397 LRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYR 456
Query: 1310 GKYGESRHSQGINWYHWKGHEFSIPFVEMKMRP 1342
G + S+H GI W ++G +S+ V+M ++P
Sbjct: 457 GGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKP 489
>gi|29893555 angiopoietin-like 6 [Homo sapiens]
Length = 470
Score = 185 bits (470), Expect = 2e-46
Identities = 90/213 (42%), Positives = 129/213 (60%), Gaps = 9/213 (4%)
Query: 1136 QDCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWA 1195
QDCA+ G SGVY + + + + V+C+ +GGGW V QRRQ+G +FF W
Sbjct: 258 QDCAEARQAGHEQSGVYELRVGRHV---VSVWCEQQLEGGGWTVIQRRQDGSVNFFTTWQ 314
Query: 1196 DYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRD-GQEAAFASYDRFSVEDSRNLYK 1254
Y+ GFG + E+WLGL+ ++++TS+G +EL V + D G A A YD FS+E + Y+
Sbjct: 315 HYKAGFGRPDGEYWLGLEPVYQLTSRGDHELLVLLEDWGGRGARAHYDGFSLEPESDHYR 374
Query: 1255 LRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYG- 1313
LR+G Y+G AGDSLS+H +PFST DRD D NCA+ +G WWY C +NLNG +
Sbjct: 375 LRLGQYHGDAGDSLSWHNDKPFSTVDRDRDSYSGNCALYQRGGWWYHACAHSNLNGVWHH 434
Query: 1314 ----ESRHSQGINWYHWKGHEFSIPFVEMKMRP 1342
SR+ G+ W ++G +S+ M +RP
Sbjct: 435 GGHYRSRYQDGVYWAEFRGGAYSLRKAAMLIRP 467
>gi|10863949 angiopoietin-like 7 [Homo sapiens]
Length = 346
Score = 184 bits (468), Expect = 4e-46
Identities = 103/278 (37%), Positives = 152/278 (54%), Gaps = 24/278 (8%)
Query: 1072 VLTYKSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRV 1131
V+ +S + + DAE + + ++ + LQAAQ T +S +
Sbjct: 81 VMELESNSKRMESRLTDAESKYSEMNNQID----IMQLQAAQTVTQTSADAI-------- 128
Query: 1132 FPHPQDCAQHLMNGDTLSGVYPIFLNGEL-SQKLQVYCDMTTDGGGWIVFQRRQNGQTDF 1190
DC+ +SGVY + + L S +L+V+CDM T GGGW + QRR++G F
Sbjct: 129 ----YDCSSLYQKNYRISGVYKLPPDDFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSF 184
Query: 1191 FRKWADYRVGFGNVEDEFWLGLDNIHRITSQGRYELRVDMRDGQ-EAAFASYDRFSVEDS 1249
+R W Y+ GFG++ +FWLG ++IHR++ Q LRV+M D + +A Y F + +
Sbjct: 185 YRDWKQYKQGFGSIRGDFWLGNEHIHRLSRQPT-RLRVEMEDWEGNLRYAEYSHFVLGNE 243
Query: 1250 RNLYKLRIGSYNGTAG-DSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNL 1308
N Y+L +G+Y G G D+L YH FST+D+DND + CA KG +WY C +NL
Sbjct: 244 LNSYRLFLGNYTGNVGNDALQYHNNTAFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNL 303
Query: 1309 NGKY---GE-SRHSQGINWYHWKGHEFSIPFVEMKMRP 1342
NG Y GE ++H GI WY W G +S+ VEMK+RP
Sbjct: 304 NGVYYRLGEHNKHLDGITWYGWHGSTYSLKRVEMKIRP 341
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 177 bits (450), Expect = 5e-44
Identities = 171/675 (25%), Positives = 292/675 (43%), Gaps = 62/675 (9%)
Query: 316 EGYQGPDCSAVAP-PEDLRVAGISDRSIELEWDGPMAVTEYVISYQPTA--LGGLQLQQR 372
EG +G + + P DL + +++ S+ ++WD + Y+I Y P L G + + +
Sbjct: 432 EGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDEKEMK 491
Query: 373 VPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVAT-HLSTPQGLQFKTITETTV 431
+ + + ++ L P Y ++VYA+ S P+T + T LS P+ L+ + +
Sbjct: 492 IGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSA 551
Query: 432 EVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSD-VTSFNQTGLKPGEEYIVNVVALKEQ 490
+ W+P S +G+ I + N +G I +V D +T+F GL P EY + + ++ ++
Sbjct: 552 RLTWDPTSRQINGYRIVY--NNADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDE 609
Query: 491 ARSPPTSASVSTVIDGPTQILVRDVSDTVAF-VEWIPPRAKVDFILLKYGLVGGEGGRT- 548
+S P + +T Q L D T +F V W P A D L K + GG+T
Sbjct: 610 GQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSA--DEGLHKLMWIPVYGGKTE 667
Query: 549 TFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDA------------ 596
L+ + ++ L PG+ YEVS+ AV T T +D+
Sbjct: 668 EVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPT 727
Query: 597 ----------PKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHE----VLVP 642
+NL VG T +SL ++WD S+++VQ+++V Y T G+ E V+VP
Sbjct: 728 TSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVP 787
Query: 643 RGIGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPATMNARTELDS-PRDLMVTASSETS 701
G L L+P TEY V ++ + + V + +T S P++L V+
Sbjct: 788 ---GSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNR 844
Query: 702 ISLIWTKASGPIDHYRITFTPSS--GIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERG 759
+ + W S P+ YRI + P S G E V D + +T+L G +Y + + A +
Sbjct: 845 LRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQA 904
Query: 760 RQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMME 819
S T T F +++L HV +S+ W ++ S +D +++
Sbjct: 905 SGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHATAYRVVIESLQDRQKQEST 964
Query: 820 VSLDATKRHAVLMGLQPATEYIVNL-----------VAVHGTVTSEPIVGSITTGIDPPK 868
V T RH GLQP +EY +++ V++ S P PP
Sbjct: 965 VG-GGTTRHC-FYGLQPDSEYKISVYTKLQEIEGPSVSIMEKTQSLPTRPPTFPPTIPPA 1022
Query: 869 DITISNVTKDSVMV---SWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNP 925
D V + SWS +F+ +S+ + VG L+ T +P
Sbjct: 1023 KEVCKAAKADLVFMVDGSWSIGDENFNKI-ISFLYSTVGALNKIGTDGTQVAMVQFTDDP 1081
Query: 926 ATEYEISLNSVRGRE 940
TE++ LN+ + +E
Sbjct: 1082 RTEFK--LNAYKTKE 1094
Score = 167 bits (424), Expect = 5e-41
Identities = 157/564 (27%), Positives = 241/564 (42%), Gaps = 53/564 (9%)
Query: 597 PKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDL 656
P L TA S + W ++ V++Y+VVY G + EV+V G + L +L
Sbjct: 356 PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVD---GTVSSTVLKNL 412
Query: 657 VPGTEYGVGISAVMNSQQSVPATMNARTELDSPR--DLMVTASSETSISLIWTKASGPID 714
+ TEY + + A+ S T L P DL++ +E S+ + W G
Sbjct: 413 MSLTEYQIAVFAIYAHTAS-EGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-S 470
Query: 715 HYRITFTP-SSGIAS---EVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDA 770
Y I + P + G+A E+ + + T L+ L P EY ++V A G + S T
Sbjct: 471 GYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQE 530
Query: 771 FT-GFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHA 829
T P +L S+V S+S +TW S + + Y+ D E + EV +D
Sbjct: 531 TTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTE-INEVEVDPITTFP 589
Query: 830 VLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKD-ITISNVTKDSVMVSWSPPV 888
L GL P TEY + + +++ SEP+ G TT P + + I VT DS V+W P
Sbjct: 590 -LKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLS 648
Query: 889 ASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTL 948
A +++ + P G+ + V+ I L P TEYE+SL +V + T
Sbjct: 649 ADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTA 708
Query: 949 VHTAMDNPVDLIATNITPTEAL----------------------LQWKAPVGEVENYVIV 986
V T +D+ AT I PT ++ ++W +V+ + +
Sbjct: 709 VGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRV- 767
Query: 987 LTHFAVAGE-------TILVDGVSEEFRLVDLLPSTHY--TATMYATNGPLTSGTISTNF 1037
T+ G+ T++V G L LLP T Y T T T+G S +S
Sbjct: 768 -TYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVS--VSAPG 824
Query: 1038 STL-LDPPANLTASEVTRQSALISWQPPRAEIENYVLTYK--STDGSRKELIVDAEDTWI 1094
TL P NL SE I+W PP + ++ Y + YK S G E V A+ I
Sbjct: 825 KTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTI 884
Query: 1095 RLEGLLENTDYTVLLQAAQDTTWS 1118
+ LL DY V + A+Q + +S
Sbjct: 885 LITNLLSGMDYNVKIFASQASGFS 908
Score = 143 bits (360), Expect = 1e-33
Identities = 147/650 (22%), Positives = 269/650 (41%), Gaps = 44/650 (6%)
Query: 410 KVATHLST--PQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVT 467
K + H T P L +T + V W + + + + + P V V+
Sbjct: 346 KASAHAITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVS 405
Query: 468 SFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTV-IDGPTQILVRDVSDTVAFVEWIP 526
S L EY + V A+ S + +T+ + + +L+ DV++ V+W
Sbjct: 406 STVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDA 465
Query: 527 PRAKVDFILLKYGLVGG-EGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNESDS 585
+++L L G G ++ + + L P + Y V+V A+ G SD
Sbjct: 466 VPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDP 525
Query: 586 ATTQFTT-EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRG 644
T Q TT + P+NLR+ + + S L WD + ++ Y++VY+ G + +EV
Sbjct: 526 VTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEV----E 581
Query: 645 IGPTTRATLTDLVPGTEYGVGISAVMNSQQSVPAT-MNARTELDSPRDLMVTASSETSIS 703
+ P T L L P TEY + I ++ + QS P T + E+ + + L + + S
Sbjct: 582 VDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFR 641
Query: 704 LIWTKASGPIDHYRITFTP-SSGIASEVTVPKDRTSYTLTDLEPGAEYIISVTA------ 756
+ W S +++ + P G EV + +++ S+ + LEPG EY +S+ A
Sbjct: 642 VTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGS 701
Query: 757 ERGRQQSLESTVDAF-----TGFRP-----------ISHLHFSHVTSSSVNITW--SDPS 798
E ++ +T+D+F T P I +L T+SS+ + W SD
Sbjct: 702 ESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSD 761
Query: 799 PPADRLILNYSPRDEEEEMM-EVSLDATKRHAVLMGLQPATEYIVNLVAVH----GTVTS 853
R+ + D EEE++ V + ++ + +L L P TEY V + ++ G S
Sbjct: 762 VQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVS 821
Query: 854 EPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVP 912
P T P+++ +S + + ++W PP + YR+ Y+P V G + V
Sbjct: 822 AP---GKTLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVG 878
Query: 913 NTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQ 972
+ IT L +Y + + + + S+ + +V T +L A ++ T
Sbjct: 879 ADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAH 938
Query: 973 WKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMY 1022
W+ V++ + + V G + L P + Y ++Y
Sbjct: 939 WQVHRHATAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVY 988
Score = 119 bits (298), Expect = 2e-26
Identities = 87/269 (32%), Positives = 133/269 (49%), Gaps = 9/269 (3%)
Query: 866 PPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSVVPNTVTEFTITRLNP 925
PP ++ S VT S MV+W+ + + YRV Y PT+ G+ D VV TV+ + L
Sbjct: 355 PPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMS 414
Query: 926 ATEYEISLNSVRGREESERI-CTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYV 984
TEY+I++ ++ SE + T A+ DL+ ++T ++W A G Y+
Sbjct: 415 LTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG-ASGYL 473
Query: 985 IV---LTHFAVAGETILVDGVSE-EFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTL 1040
I+ LT E + G + + L LLP+T YT T+YA G S ++ +TL
Sbjct: 474 ILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL 533
Query: 1041 -LDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSR-KELIVDAEDTWIRLEG 1098
L PP NL S V SA ++W P +I Y + Y + DG+ E+ VD T+ L+G
Sbjct: 534 ALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTEINEVEVDPITTF-PLKG 592
Query: 1099 LLENTDYTVLLQAAQDTTWSSITSTAFTT 1127
L T+YT+ + + D S + FTT
Sbjct: 593 LTPLTEYTIAIFSIYDEGQSEPLTGVFTT 621
Score = 110 bits (274), Expect = 1e-23
Identities = 171/750 (22%), Positives = 294/750 (39%), Gaps = 97/750 (12%)
Query: 411 VATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFN 470
V ++ P L++ I+ ++++ W+ F G+++ P + + + T
Sbjct: 26 VQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAI 85
Query: 471 QTGLKPGEEYIVNVVALKEQARSPPTSAS-----VSTVIDGPTQILVRDVS--------D 517
GL P + Y V ++A + S P + D ++ V D +
Sbjct: 86 IQGLMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPE 145
Query: 518 TVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGS-RYEVSVSA 576
V FV P A D ++L G GR FRL + V A GS + + ++
Sbjct: 146 EVKFVCQTP--AIADIVILVDG--SWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQ 201
Query: 577 VRGTNESDSATTQFTTE---IDAPKNLRV-GSRTATSLDLEW--DNSEAEVQEYKVVYST 630
G + F+T+ I+A +NL G T T L L + +NS +K +
Sbjct: 202 YSGDPRIEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENS------FKPEAGS 255
Query: 631 LAGEQYHEVLVPRGIGPTTRATLTDLVPGT----EYGVGISAVMNSQQSVPATMNARTEL 686
G +L+ G + D++P + E GV + A+ V +E
Sbjct: 256 RTGVSKIGILITDG------KSQDDIIPPSRNLRESGVELFAIGVKNADVNELQEIASEP 309
Query: 687 DSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIASEVTVPKDRTSYTLTDLEP 746
DS ++ A + H T +E
Sbjct: 310 DSTH--------------VYNVAEFDLMH--------------------------TVVES 329
Query: 747 GAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLIL 806
+ S E+ R+ ++++ A TG P + L S VT+ S + W+ ++ +
Sbjct: 330 LTRTLCSRVEEQDRE--IKASAHAITG--PPTELITSEVTARSFMVNWTHAPGNVEKYRV 385
Query: 807 NYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITT-GID 865
Y P + EV +D T VL L TEY + + A++ SE + G+ TT +
Sbjct: 386 VYYPT-RGGKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALP 444
Query: 866 PPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDSSV---VPNTVTEFTITR 922
D+ + +VT++S+ V W V Y + Y P G + T T+ ++
Sbjct: 445 MASDLLLYDVTENSMRVKWDA-VPGASGYLILYAPLTEGLAGDEKEMKIGETHTDIELSG 503
Query: 923 LNPATEYEISLNSVRGREESERICTLVHT-AMDNPVDLIATNITPTEALLQWKAPVGEVE 981
L P TEY +++ ++ G E S+ + T A+ P +L +N+ A L W ++
Sbjct: 504 LLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQIN 563
Query: 982 NYVIVLTHF-AVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTL 1040
Y IV + + VD ++ F L L P T YT +++ S ++ F+T
Sbjct: 564 GYRIVYNNADGTEINEVEVDPITT-FPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTE 622
Query: 1041 LDPPAN-LTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIV--DAEDTWIRLE 1097
P L EVT S ++W P A+ + L + G + E +V + +D+ + +E
Sbjct: 623 EVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHV-IE 681
Query: 1098 GLLENTDYTVLLQAAQDTTWSSITSTAFTT 1127
GL T+Y V L A D S TA T
Sbjct: 682 GLEPGTEYEVSLLAVLDDGSESEVVTAVGT 711
Score = 56.2 bits (134), Expect = 2e-07
Identities = 48/195 (24%), Positives = 82/195 (42%), Gaps = 6/195 (3%)
Query: 309 EGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGL 367
EG+ V G P P++LRV+ + + WD P + V Y I Y+P ++ G
Sbjct: 816 EGVSVSAPGKTLPSSG----PQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGP 871
Query: 368 QLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTIT 427
L+ V D + + IT L G+ YN+ ++A ++ S +T V T LQ K +
Sbjct: 872 TLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVE 931
Query: 428 ETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVAL 487
T++ W+ + + + + + V T GL+P EY ++V
Sbjct: 932 MTSLCAHWQVHRHA-TAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTK 990
Query: 488 KEQARSPPTSASVST 502
++ P S T
Sbjct: 991 LQEIEGPSVSIMEKT 1005
Score = 31.2 bits (69), Expect = 7.1
Identities = 21/82 (25%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 946 CTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGET--ILVDGVS 1003
CT+V + P L I+ + WKAP G+ Y +++T + G+T + + +
Sbjct: 23 CTIVQGQVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTS-GGKTNQLNLQNTA 81
Query: 1004 EEFRLVDLLPSTHYTATMYATN 1025
+ + L+P +YT + A N
Sbjct: 82 TKAIIQGLMPDQNYTVQIIAYN 103
Score = 30.8 bits (68), Expect = 9.2
Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 2/73 (2%)
Query: 326 VAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTITE 384
VAPP LR IS SI++ W P Y + PT+ GG Q + + I
Sbjct: 30 VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTS-GGKTNQLNLQNTATKAIIQG 88
Query: 385 LEPGLTYNISVYA 397
L P Y + + A
Sbjct: 89 LMPDQNYTVQIIA 101
>gi|42544202 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 173 bits (439), Expect = 9e-43
Identities = 95/225 (42%), Positives = 126/225 (56%), Gaps = 21/225 (9%)
Query: 1137 DCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWAD 1196
DC++ +G LSG Y I + + VYCDM+ DGGGW V QRR +G +F R W D
Sbjct: 82 DCSEIFNDGYKLSGFYKI-KPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKD 139
Query: 1197 YRVGFGNV---EDEFWLGLDNIHRITSQGRYELRVDMRDGQE-AAFASYDRFSVEDSRNL 1252
Y GFGN E+WLG N+H +T+Q Y L++D+ D ++ + +A Y F V D +N
Sbjct: 140 YENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNF 199
Query: 1253 YKLRIGSYNGTAGDSLS-----------YHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYK 1301
Y+L IG Y+GTAGDSL+ HQ FST DRD+D NCA + WW+
Sbjct: 200 YELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFN 259
Query: 1302 NCHRTNLNGKYGE----SRHSQGINWYHWKGHEFSIPFVEMKMRP 1342
CH NLNG Y ++ GI WY W G +S+ V MK+RP
Sbjct: 260 RCHSANLNGVYYSGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRP 304
>gi|42544200 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 173 bits (439), Expect = 9e-43
Identities = 95/225 (42%), Positives = 126/225 (56%), Gaps = 21/225 (9%)
Query: 1137 DCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWAD 1196
DC++ +G LSG Y I + + VYCDM+ DGGGW V QRR +G +F R W D
Sbjct: 82 DCSEIFNDGYKLSGFYKI-KPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKD 139
Query: 1197 YRVGFGNV---EDEFWLGLDNIHRITSQGRYELRVDMRDGQE-AAFASYDRFSVEDSRNL 1252
Y GFGN E+WLG N+H +T+Q Y L++D+ D ++ + +A Y F V D +N
Sbjct: 140 YENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNF 199
Query: 1253 YKLRIGSYNGTAGDSLS-----------YHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYK 1301
Y+L IG Y+GTAGDSL+ HQ FST DRD+D NCA + WW+
Sbjct: 200 YELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFN 259
Query: 1302 NCHRTNLNGKYGE----SRHSQGINWYHWKGHEFSIPFVEMKMRP 1342
CH NLNG Y ++ GI WY W G +S+ V MK+RP
Sbjct: 260 RCHSANLNGVYYSGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRP 304
>gi|42544198 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 173 bits (439), Expect = 9e-43
Identities = 95/225 (42%), Positives = 126/225 (56%), Gaps = 21/225 (9%)
Query: 1137 DCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWAD 1196
DC++ +G LSG Y I + + VYCDM+ DGGGW V QRR +G +F R W D
Sbjct: 82 DCSEIFNDGYKLSGFYKI-KPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKD 139
Query: 1197 YRVGFGNV---EDEFWLGLDNIHRITSQGRYELRVDMRDGQE-AAFASYDRFSVEDSRNL 1252
Y GFGN E+WLG N+H +T+Q Y L++D+ D ++ + +A Y F V D +N
Sbjct: 140 YENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNF 199
Query: 1253 YKLRIGSYNGTAGDSLS-----------YHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYK 1301
Y+L IG Y+GTAGDSL+ HQ FST DRD+D NCA + WW+
Sbjct: 200 YELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFN 259
Query: 1302 NCHRTNLNGKYGE----SRHSQGINWYHWKGHEFSIPFVEMKMRP 1342
CH NLNG Y ++ GI WY W G +S+ V MK+RP
Sbjct: 260 RCHSANLNGVYYSGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRP 304
>gi|42544189 fibrinogen-like 1 precursor [Homo sapiens]
Length = 312
Score = 173 bits (439), Expect = 9e-43
Identities = 95/225 (42%), Positives = 126/225 (56%), Gaps = 21/225 (9%)
Query: 1137 DCAQHLMNGDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWAD 1196
DC++ +G LSG Y I + + VYCDM+ DGGGW V QRR +G +F R W D
Sbjct: 82 DCSEIFNDGYKLSGFYKI-KPLQSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKD 139
Query: 1197 YRVGFGNV---EDEFWLGLDNIHRITSQGRYELRVDMRDGQE-AAFASYDRFSVEDSRNL 1252
Y GFGN E+WLG N+H +T+Q Y L++D+ D ++ + +A Y F V D +N
Sbjct: 140 YENGFGNFVQKHGEYWLGNKNLHFLTTQEDYTLKIDLADFEKNSRYAQYKNFKVGDEKNF 199
Query: 1253 YKLRIGSYNGTAGDSLS-----------YHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYK 1301
Y+L IG Y+GTAGDSL+ HQ FST DRD+D NCA + WW+
Sbjct: 200 YELNIGEYSGTAGDSLAGNFHPEVQWWASHQRMKFSTWDRDHDNYEGNCAEEDQSGWWFN 259
Query: 1302 NCHRTNLNGKYGE----SRHSQGINWYHWKGHEFSIPFVEMKMRP 1342
CH NLNG Y ++ GI WY W G +S+ V MK+RP
Sbjct: 260 RCHSANLNGVYYSGPYTAKTDNGIVWYTWHGWWYSLKSVVMKIRP 304
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,462,304
Number of Sequences: 37866
Number of extensions: 2650551
Number of successful extensions: 15081
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 383
Number of HSP's that attempted gapping in prelim test: 6452
Number of HSP's gapped (non-prelim): 3707
length of query: 1358
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1243
effective length of database: 13,892,928
effective search space: 17268909504
effective search space used: 17268909504
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.