Search of human proteins with 157057545

Search of human proteins with 157057545

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
         (624 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157057545 sorting nexin 18 isoform a [Homo sapiens]               1286   0.0  
gi|224177511 sorting nexin 18 isoform c [Homo sapiens]               1122   0.0  
gi|157057543 sorting nexin 18 isoform b [Homo sapiens]               1122   0.0  
gi|23397574 sorting nexin 33 [Homo sapiens]                           587   e-168
gi|7706706 sorting nexin 9 [Homo sapiens]                             357   2e-98
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       93   8e-19
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]       93   8e-19
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]       85   2e-16
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]       85   2e-16
gi|153791707 sorting nexin family member 30 [Homo sapiens]             74   4e-13
gi|23111055 sorting nexin 7 isoform b [Homo sapiens]                   67   4e-11
gi|194294540 sorting nexin 7 isoform a [Homo sapiens]                  67   4e-11
gi|23943858 sorting nexin 8 [Homo sapiens]                             62   2e-09
gi|239745060 PREDICTED: similar to breast cancer anti-estrogen r...    60   8e-09
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]    57   5e-08
gi|239756225 PREDICTED: similar to breast cancer anti-estrogen r...    56   1e-07
gi|239750776 PREDICTED: similar to breast cancer anti-estrogen r...    56   1e-07
gi|239745044 PREDICTED: similar to breast cancer anti-estrogen r...    56   1e-07
gi|4507145 sorting nexin 4 [Homo sapiens]                              55   2e-07
gi|19224660 protein kinase C and casein kinase substrate in neur...    53   7e-07
gi|23111036 sorting nexin 1 isoform c [Homo sapiens]                   51   3e-06
gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]                     51   4e-06
gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]                       50   5e-06
gi|24308229 protein kinase C and casein kinase substrate in neur...    50   6e-06
gi|148747351 protein kinase C and casein kinase substrate in neu...    50   6e-06
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...    50   6e-06
gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens]                       50   6e-06
gi|23111034 sorting nexin 1 isoform a [Homo sapiens]                   50   8e-06
gi|23111026 sorting nexin 11 [Homo sapiens]                            50   8e-06
gi|23111028 sorting nexin 11 [Homo sapiens]                            50   8e-06

>gi|157057545 sorting nexin 18 isoform a [Homo sapiens]
          Length = 624

 Score = 1286 bits (3327), Expect = 0.0
 Identities = 624/624 (100%), Positives = 624/624 (100%)

Query: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60
           MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR
Sbjct: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60

Query: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120
           APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ
Sbjct: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120

Query: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180
           PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD
Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180

Query: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240
           GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG
Sbjct: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240

Query: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300
           EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL
Sbjct: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300

Query: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360
           VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM
Sbjct: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360

Query: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420
           NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD
Sbjct: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420

Query: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480
           LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL
Sbjct: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480

Query: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540
           DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK
Sbjct: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540

Query: 541 GALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFL 600
           GALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFL
Sbjct: 541 GALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFL 600

Query: 601 QQQIIFFQKVTQKLEEALHKYDSV 624
           QQQIIFFQKVTQKLEEALHKYDSV
Sbjct: 601 QQQIIFFQKVTQKLEEALHKYDSV 624


>gi|224177511 sorting nexin 18 isoform c [Homo sapiens]
          Length = 591

 Score = 1122 bits (2901), Expect = 0.0
 Identities = 541/541 (100%), Positives = 541/541 (100%)

Query: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60
           MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR
Sbjct: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60

Query: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120
           APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ
Sbjct: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120

Query: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180
           PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD
Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180

Query: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240
           GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG
Sbjct: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240

Query: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300
           EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL
Sbjct: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300

Query: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360
           VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM
Sbjct: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360

Query: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420
           NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD
Sbjct: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420

Query: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480
           LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL
Sbjct: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480

Query: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540
           DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK
Sbjct: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540

Query: 541 G 541
           G
Sbjct: 541 G 541


>gi|157057543 sorting nexin 18 isoform b [Homo sapiens]
          Length = 628

 Score = 1122 bits (2901), Expect = 0.0
 Identities = 541/541 (100%), Positives = 541/541 (100%)

Query: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60
           MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR
Sbjct: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60

Query: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120
           APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ
Sbjct: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120

Query: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180
           PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD
Sbjct: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVADEPGALGSGAYPDLD 180

Query: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240
           GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG
Sbjct: 181 GSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFSTFVKSGG 240

Query: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300
           EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL
Sbjct: 241 EAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMKSYISYKL 300

Query: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360
           VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM
Sbjct: 301 VPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWM 360

Query: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420
           NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD
Sbjct: 361 NHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALD 420

Query: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480
           LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL
Sbjct: 421 LQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFEL 480

Query: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540
           DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK
Sbjct: 481 DQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQK 540

Query: 541 G 541
           G
Sbjct: 541 G 541


>gi|23397574 sorting nexin 33 [Homo sapiens]
          Length = 574

 Score =  587 bits (1514), Expect = e-168
 Identities = 318/631 (50%), Positives = 412/631 (65%), Gaps = 64/631 (10%)

Query: 1   MALRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60
           MAL+ RALYDF SEN  EIS+++ E L + SE  ++GWL+G NSRG+ GLFPASYV+++R
Sbjct: 1   MALKGRALYDFHSENKEEISIQQDEDLVIFSETSLDGWLQGQNSRGETGLFPASYVEIVR 60

Query: 61  APEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQ 120
           +        G     A Y++ P G                P A  +L        PS   
Sbjct: 61  S--------GISTNHADYSSSPAGS---------------PGAQVSLYNS-----PSVAS 92

Query: 121 PPGAGFPYGGGALQPSPQQLYGGYQASQGS-----DDDWDDEWDDSSTVADEP--GALGS 173
           P  +G    GG+          G+ ++QGS     DDDWDD WDD  TV +EP  G LG+
Sbjct: 93  PARSG----GGS----------GFLSNQGSFEEDDDDDWDD-WDDGCTVVEEPRAGGLGT 137

Query: 174 GAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATVSRNLNRFS 233
             +P L+ S     GA     ++ R    L         Q   +  K  + V RNLNRFS
Sbjct: 138 NGHPPLNLSYP---GAYPSQHMAFRPKPPLER-------QDSLASAKRGSVVGRNLNRFS 187

Query: 234 TFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTKQTKFKGMK 293
            FV+SG EAF+LG+     K  +   + +GP GP+W+ NP+PF C+++DPTKQTKFKG+K
Sbjct: 188 CFVRSGVEAFILGDVPMMAKIAETYSIEMGPRGPQWKANPHPFACSVEDPTKQTKFKGIK 247

Query: 294 SYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRR 353
           SYISYKL PTH   PV+RRYKHFDWLY RL  KF VISVPHLPEKQATGRFEEDFI KR+
Sbjct: 248 SYISYKLTPTHAASPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIEKRK 307

Query: 354 KGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLST 413
           + LI WM+HM SHPVL+Q + FQHFL+C    D+K WK GKR+AEKDEMVGA+F LT   
Sbjct: 308 RRLILWMDHMTSHPVLSQYEGFQHFLSC---LDDKQWKMGKRRAEKDEMVGASFLLTFQI 364

Query: 414 PPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEYQKVGQSFRG 473
            P    DLQ+VE ++D FK F+KKMDDS LQL+  A+E  RK V GF+KE+QK+G +F+ 
Sbjct: 365 -PTEHQDLQDVEDRVDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQA 423

Query: 474 LSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFP 533
           +S +F++D    S  LN AI+ TG  Y+AIGE+FAEQP+ DL  ++D L+LYQG L+NFP
Sbjct: 424 ISHSFQMDPPFCSEALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFP 483

Query: 534 DIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFK 593
           DIIH+QKGA  KVKES+R  +EG+M   +ADGI+ RC  + FA  AE++HFHQ R  DFK
Sbjct: 484 DIIHLQKGAFAKVKESQRMSDEGRMVQDEADGIRRRCRVVGFALQAEMNHFHQRRELDFK 543

Query: 594 SQMQHFLQQQIIFFQKVTQKLEEALHKYDSV 624
             MQ++L+QQI+F+Q+V Q+LE+ L  YD++
Sbjct: 544 HMMQNYLRQQILFYQRVGQQLEKTLRMYDNL 574


>gi|7706706 sorting nexin 9 [Homo sapiens]
          Length = 595

 Score =  357 bits (915), Expect = 2e-98
 Identities = 228/637 (35%), Positives = 325/637 (51%), Gaps = 61/637 (9%)

Query: 1   MALRARALYDFRSENPG--EISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQV 58
           MA +AR +YDF +E PG  E+++ E E++++ +     GWLEG N +G+RGL P  YV++
Sbjct: 1   MATKARVMYDFAAE-PGNNELTVNEGEIITITNPDVGGGWLEGRNIKGERGLVPTDYVEI 59

Query: 59  IRAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPA------SFKPPPDAFQALLQPQ- 111
           + +        G   A   + +           +  +      S   P  A+ A      
Sbjct: 60  LPSDGKDQFSCGNSVADQAFLDSLSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNW 119

Query: 112 QAPPPSTFQPPGAGF------PYGGGALQPSPQQLYGGYQASQGSDDDWDDEWDDSSTVA 165
           ++      QP GAG       P         PQ   G    + G DDDWD++WD      
Sbjct: 120 ESSEGWGAQPEGAGAQRNTNTPNNWDTAFGHPQAYQG---PATGDDDDWDEDWD------ 170

Query: 166 DEPGALGSGAYPDLDGSSSAGVGAAGRYRLSTRSDLSLGSRGGSVPPQHHPSGPKSSATV 225
              G   S  + D   S SA  G A               RG S           SS+++
Sbjct: 171 ---GPKSSSYFKD---SESADAGGA--------------QRGNS---------RASSSSM 201

Query: 226 SRNLNRFSTFVKSGGEAFVLGEASGFVKDGDKLCVVLGPYGPEWQENPYPFQCTIDDPTK 285
              LN+F  F K G E ++L  A    K  +K+ +++G YGP W      F C + DP K
Sbjct: 202 KIPLNKFPGFAKPGTEQYLL--AKQLAKPKEKIPIIVGDYGPMWVYPTSTFDCVVADPRK 259

Query: 286 QTKFKGMKSYISYKLVPTHTQVPVHRRYKHFDWLYARLAEKF-PVISVPHLPEKQATGRF 344
            +K  G+KSYI Y+L PT+T   V+ RYKHFDWLY RL  KF   I +P LP+KQ TGRF
Sbjct: 260 GSKMYGLKSYIEYQLTPTNTNRSVNHRYKHFDWLYERLLVKFGSAIPIPSLPDKQVTGRF 319

Query: 345 EEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVG 404
           EE+FI  R + L  WM  M  HPV+++ +VFQ FL   +  DEK WK GKRKAE+DE+ G
Sbjct: 320 EEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFL---NFRDEKEWKTGKRKAERDELAG 376

Query: 405 ANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTGFKKEY 464
              F T+  P A  LDL E+E K +    FTK MDD   +L     E  ++      KEY
Sbjct: 377 VMIFSTME-PEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQEHWKRCTGPLPKEY 435

Query: 465 QKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLAL 524
           QK+G++ + L+  F          LN AI   G  Y+ I  L AEQP++DL  +M+    
Sbjct: 436 QKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPKKDLHFLMECNHE 495

Query: 525 YQGHLANFPDIIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHF 584
           Y+G L  FPDII   KGA+ KVKES + V   K+ +Q    +  R + +S+A  AE++HF
Sbjct: 496 YKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYALQAEMNHF 555

Query: 585 HQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEALHKY 621
           H  R+ D+ S ++ +L+QQ+ F++ + +KL +AL ++
Sbjct: 556 HSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRF 592


>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1363

 Score = 92.8 bits (229), Expect = 8e-19
 Identities = 44/65 (67%), Positives = 51/65 (78%)

Query: 498  DAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGK 557
            DA++ +GEL A QP Q+LDPVMDLL L QGH  N PDIIH+ K ALTKV ESR+HV EGK
Sbjct: 1283 DAFNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGK 1342

Query: 558  MEVQK 562
             EVQ+
Sbjct: 1343 TEVQR 1347


>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
          Length = 1366

 Score = 92.8 bits (229), Expect = 8e-19
 Identities = 44/65 (67%), Positives = 51/65 (78%)

Query: 498  DAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGK 557
            DA++ +GEL A QP Q+LDPVMDLL L QGH  N PDIIH+ K ALTKV ESR+HV EGK
Sbjct: 1286 DAFNTVGELXANQPIQELDPVMDLLVLSQGHQVNIPDIIHIHKEALTKVMESRQHVAEGK 1345

Query: 558  MEVQK 562
             EVQ+
Sbjct: 1346 TEVQR 1350


>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1415

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 41/65 (63%), Positives = 49/65 (75%)

Query: 498  DAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGK 557
            DA++ +GELFA QP Q+LDPVMDLL L  GH     DIIH+ K ALTKV ESR+HV EGK
Sbjct: 1335 DAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHKEALTKVMESRQHVAEGK 1394

Query: 558  MEVQK 562
             E+Q+
Sbjct: 1395 TEMQR 1399


>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
          Length = 1415

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 41/65 (63%), Positives = 49/65 (75%)

Query: 498  DAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPDIIHVQKGALTKVKESRRHVEEGK 557
            DA++ +GELFA QP Q+LDPVMDLL L  GH     DIIH+ K ALTKV ESR+HV EGK
Sbjct: 1335 DAFNTVGELFANQPSQELDPVMDLLVLSLGHQVIILDIIHIHKEALTKVMESRQHVAEGK 1394

Query: 558  MEVQK 562
             E+Q+
Sbjct: 1395 TEMQR 1399


>gi|153791707 sorting nexin family member 30 [Homo sapiens]
          Length = 437

 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 86/355 (24%), Positives = 143/355 (40%), Gaps = 38/355 (10%)

Query: 280 IDDPTKQTKFKGMKSYISYKLVPTHTQVP-------VHRRYKHFDWLYARLAEKFPVISV 332
           +DDP K      M++YI+Y++    T+V        V RRY+ FDWL ++L E  P   +
Sbjct: 95  VDDPKKHVCT--METYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLI 152

Query: 333 PHLPE----KQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEK 388
           P LPE    K    RF E+F+  RRK L  ++  +  HPVL+  + F  FLT       K
Sbjct: 153 PPLPEKFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAKDLNAYK 212

Query: 389 AWKQG----KRKAEKDEMVGANFFLTLSTPPAAALDLQEVESKIDGFKCFTKKMDDSALQ 444
             KQG     R  E  + V   +   L T P   L+   +   +D F      +D  A +
Sbjct: 213 --KQGIALLTRMGESVKHVTGGY--KLRTRP---LEFAAIGDYLDTFALKLGTIDRIAQR 265

Query: 445 LNHTANEFARKQVTGFKKEYQKVGQSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIG 504
           +     E+  +      +EY  V  ++  L       +   +  L    A  G+   A+ 
Sbjct: 266 IIKEEIEYLVE-----LREYGPVYSTWSAL-------EGELAEPLEGVSACIGNCSTALE 313

Query: 505 ELFAEQPRQDLDPVMDLLALYQGHLAN-FPDIIHVQKGALTKVKESRRHVEEGKMEVQKA 563
           EL  +   +D  PV+    LY   + +       VQ     K++      E+        
Sbjct: 314 EL-TDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYEAKLEAVALRKEDRPKVPADV 372

Query: 564 DGIQDRCNTISFATLAEIHHFHQIRVRDFKSQMQHFLQQQIIFFQKVTQKLEEAL 618
           +  QDR    +    A++  +   + +DF+  +     + I +++K     E  +
Sbjct: 373 EKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMAWESII 427


>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
          Length = 336

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 19/131 (14%)

Query: 279 TIDDPTKQTKFKGMKSYISYKLVPT-------HTQVPVHRRYKHFDWLYARLAEKFPVIS 331
           T+D+P  ++    ++++I+Y+++          ++  V RRY+ F WL  +L E  P + 
Sbjct: 35  TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 92

Query: 332 VPHLPEK----QATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDE 387
           +P LPEK        RF +DFI  RRK L  ++N +A HP L   + F+ FLT       
Sbjct: 93  IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA------ 146

Query: 388 KAWKQGKRKAE 398
           +AW+    K +
Sbjct: 147 QAWELSSHKKQ 157


>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
          Length = 451

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 41/131 (31%), Positives = 68/131 (51%), Gaps = 19/131 (14%)

Query: 279 TIDDPTKQTKFKGMKSYISYKLVPT-------HTQVPVHRRYKHFDWLYARLAEKFPVIS 331
           T+D+P  ++    ++++I+Y+++          ++  V RRY+ F WL  +L E  P + 
Sbjct: 99  TVDEP--ESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLI 156

Query: 332 VPHLPEK----QATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDE 387
           +P LPEK        RF +DFI  RRK L  ++N +A HP L   + F+ FLT       
Sbjct: 157 IPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTA------ 210

Query: 388 KAWKQGKRKAE 398
           +AW+    K +
Sbjct: 211 QAWELSSHKKQ 221


>gi|23943858 sorting nexin 8 [Homo sapiens]
          Length = 465

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 61/287 (21%), Positives = 120/287 (41%), Gaps = 22/287 (7%)

Query: 295 YISYKLVPTHTQVPVHRRYKHFDWLYARLAEKFPVISVPHLPEKQATGRFEEDFISKRRK 354
           ++ Y++     +  V+RRY  F      L  KFP   VP LP K+  G  + +FI  RR+
Sbjct: 92  HVEYEVSSQRFKSSVYRRYNDFVVFQEMLLHKFPYRMVPALPPKRMLGA-DREFIEARRR 150

Query: 355 GLIWWMNHMASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTP 414
            L  ++N +A HP+ ++  V + FL+   S  +   K      E  + VG  F       
Sbjct: 151 ALKRFVNLVARHPLFSEDVVLKLFLSFSGSDVQNKLK------ESAQCVGDEFLNCKLAT 204

Query: 415 PAAALDLQEVESKIDGFKCFTKKMDDSALQLNHTANEFARKQVTG------FKKEYQKVG 468
            A      +++++    +   + + +S  +L   A   A + +        F KE   +G
Sbjct: 205 RAKDFLPADIQAQFAISRELIRNIYNSFHKLRDRAERIASRAIDNAADLLIFGKELSAIG 264

Query: 469 QSFRGLSQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGH 528
                L     L+   +   L QA+      +  + +  A+Q +Q+ + V++ L L+   
Sbjct: 265 SDTTPLPSWAALNSSTWG-SLKQALKGLSVEFALLADKAAQQGKQEENDVVEKLNLFLDL 323

Query: 529 LANFPD--------IIHVQKGALTKVKESRRHVEEGKMEVQKADGIQ 567
           L ++ D        ++H  + AL K    +R +     + ++ + ++
Sbjct: 324 LQSYKDLCERHEKGVLHKHQRALHKYSLMKRQMMSATAQNREPESVE 370



 Score = 30.0 bits (66), Expect = 6.7
 Identities = 22/63 (34%), Positives = 24/63 (38%), Gaps = 9/63 (14%)

Query: 60  RAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTF 119
           RA +P PA   G  A A                PPAS  P P A +     QQ P PS  
Sbjct: 4   RAMDPLPAAAVGAAAEAEADE---------EADPPASDLPTPQAIEPQAIVQQVPAPSRM 54

Query: 120 QPP 122
           Q P
Sbjct: 55  QMP 57


>gi|239745060 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 353

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 46/145 (31%), Positives = 76/145 (52%), Gaps = 27/145 (18%)

Query: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60
           A+ALYD  +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 8   AKALYDNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIMPGNHLKILV 64

Query: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123

Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138
                +Q PG           PSPQ
Sbjct: 124 -QQGLYQVPG-----------PSPQ 136


>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
          Length = 870

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 27/145 (18%)

Query: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQV-I 59
           A+ALYD  +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P + +++ +
Sbjct: 8   AKALYDNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNRLKILV 64

Query: 60  RAPEPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113
              +  PAG  GPG PA  A   PG   P P A       P +++P PD+   +  P +A
Sbjct: 65  GMYDKKPAGP-GPGPPATPAQPQPGLHAPAPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123

Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138
                +Q PG           PSPQ
Sbjct: 124 -QQGLYQVPG-----------PSPQ 136


>gi|239756225 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 232

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%)

Query: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60
           A+ALY   +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 8   AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64

Query: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123

Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138
                +Q PG           PSPQ
Sbjct: 124 -QQGLYQVPG-----------PSPQ 136


>gi|239750776 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 224

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%)

Query: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60
           A+ALY   +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 8   AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64

Query: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123

Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138
                +Q PG           PSPQ
Sbjct: 124 -QQGLYQVPG-----------PSPQ 136


>gi|239745044 PREDICTED: similar to breast cancer anti-estrogen
           resistance 1 [Homo sapiens]
          Length = 368

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 27/145 (18%)

Query: 5   ARALYDFRSENPGEISLREHEVLSLCSEQDIEG----WLEGVNSRGDRGLFPASYVQVIR 60
           A+ALY   +E+P E+S R+ +++++  EQD +G    WL  ++ R  +G+ P ++++++ 
Sbjct: 8   AKALYVNVAESPDELSFRKGDIMTVL-EQDTQGLDGWWLCSLHGR--QGIVPGNHLKILV 64

Query: 61  AP-EPGPAGDGGPGAPARYANVPPGGFEPLPVAP------PASFKPPPDAFQALLQPQQA 113
              +  PAG G PG PA  A   PG   P+P A       P +++P PD+   +  P +A
Sbjct: 65  GMYDKKPAGPG-PGPPATPAQPQPGLHAPVPPASQYTPMLPNTYQPQPDSVYLVPTPSKA 123

Query: 114 PPPSTFQPPGAGFPYGGGALQPSPQ 138
                +Q PG           PSPQ
Sbjct: 124 -QQGLYQVPG-----------PSPQ 136


>gi|4507145 sorting nexin 4 [Homo sapiens]
          Length = 450

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 8/126 (6%)

Query: 311 RRYKHFDWLYARLAEKFPVISVPHLPEKQA--------TGRFEEDFISKRRKGLIWWMNH 362
           RRY  F+ L + L   +P I VP LPEK+A            + DF+ +RR GL  ++  
Sbjct: 105 RRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSADNMDPDFVERRRIGLENFLLR 164

Query: 363 MASHPVLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQ 422
           +ASHP+L +  +F  FLT   +  E   + G +      +   N    +  P     DL+
Sbjct: 165 IASHPILCRDKIFYLFLTQEGNWKETVNETGFQLKADSRLKALNATFRVKNPDKRFTDLK 224

Query: 423 EVESKI 428
               ++
Sbjct: 225 HYSDEL 230


>gi|19224660 protein kinase C and casein kinase substrate in neurons
           3 [Homo sapiens]
          Length = 424

 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 25/59 (42%), Positives = 36/59 (61%)

Query: 3   LRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRA 61
           +R RALYD+  +   E+S R  E L   SE+D +GW +G    G  GL+PA+YV+ + A
Sbjct: 366 VRVRALYDYAGQEADELSFRAGEELLKMSEEDEQGWCQGQLQSGRIGLYPANYVECVGA 424


>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
          Length = 474

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 90/383 (23%), Positives = 148/383 (38%), Gaps = 87/383 (22%)

Query: 268 EWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWL 319
           E QE+ +     I DP K     GM +Y++YK V T T +P        V RR+  F  L
Sbjct: 137 EEQEDQFDLTVGITDPEKIGD--GMNAYVAYK-VTTQTSLPLFRSKQFAVKRRFSDFLGL 193

Query: 320 YARLAEKFPV--ISVPHLPEKQATGRFE----------EDFISKRRKGLIWWMNHMASHP 367
           Y +L+EK       VP  PEK   G  +           +F+ KRR  L  ++  + +HP
Sbjct: 194 YEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHP 253

Query: 368 VLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESK 427
            + Q    + FL                  EK+E+  A    TLS    A L L+     
Sbjct: 254 TMLQDPDVREFL------------------EKEELPRAVGTQTLS---GAGL-LKMFNKA 291

Query: 428 IDGFKCFTKKMDDSALQLNHTANEFARKQ------------VTGFKKEYQ-KVGQSFRGL 474
            D     T KM++S +       E   ++            +   +KE      Q  + L
Sbjct: 292 TDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSL 351

Query: 475 SQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALYQGHLANFPD 534
           +    L     +  L++A++   +  + I +L  EQ   D   + +LL+ Y   LA    
Sbjct: 352 AM---LGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLA---- 404

Query: 535 IIHVQKGALTKVKESRRHVEEGKMEVQKADGIQDRCNTISFATLAEIHHFHQIRVRDFKS 594
           I+  +    ++V +  R  E                  IS     E+  F + + +DFK+
Sbjct: 405 IVRWE----SRVTQYERDFER-----------------ISTVVRKEVIRFEKEKSKDFKN 443

Query: 595 QMQHFLQQQIIFFQKVTQKLEEA 617
            +  +L + +++ Q+   K  EA
Sbjct: 444 HVIKYL-ETLLYSQQQLAKYWEA 465


>gi|223468657 SH3-domain GRB2-like 3 [Homo sapiens]
          Length = 347

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 24/54 (44%), Positives = 36/54 (66%), Gaps = 2/54 (3%)

Query: 6   RALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVI 59
           R LYDF  EN GE+  +E ++++L ++ D E W EG+   G+ G FP +YV+VI
Sbjct: 291 RGLYDFEPENQGELGFKEGDIITLTNQID-ENWYEGM-IHGESGFFPINYVEVI 342


>gi|4506931 SH3-domain GRB2-like 2 [Homo sapiens]
          Length = 352

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 24/56 (42%), Positives = 37/56 (66%), Gaps = 2/56 (3%)

Query: 6   RALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIRA 61
           RALYDF  EN GE+  +E ++++L ++ D E W EG+   G  G FP +YV+++ A
Sbjct: 296 RALYDFEPENEGELGFKEGDIITLTNQID-ENWYEGM-LHGHSGFFPINYVEILVA 349


>gi|24308229 protein kinase C and casein kinase substrate in neurons
           1 [Homo sapiens]
          Length = 444

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 22/57 (38%), Positives = 34/57 (59%)

Query: 3   LRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVI 59
           +R RALYD+  +   E+S +  + L+   E+D +GW  G    G  GL+PA+YV+ I
Sbjct: 388 VRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEAI 444


>gi|148747351 protein kinase C and casein kinase substrate in
           neurons 2 [Homo sapiens]
          Length = 486

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 21/58 (36%), Positives = 36/58 (62%)

Query: 3   LRARALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVIR 60
           +R RALYD+  +   E+S +  + L+   ++D +GW +G    G  GL+PA+YV+ I+
Sbjct: 429 VRVRALYDYEGQEHDELSFKAGDELTKMEDEDEQGWCKGRLDNGQVGLYPANYVEAIQ 486


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 43/140 (30%), Positives = 62/140 (44%), Gaps = 24/140 (17%)

Query: 5   ARALYDFRSENPGEISLREHEVLSLCSEQ---DIEGWLEGVNSRGDRGLFPASYVQVIRA 61
           ARALYD  +E+P E+S R  +VL +   +    ++GW    +  G +G+ PA+ V+++ A
Sbjct: 10  ARALYDNTAESPQELSFRRGDVLRVLQREGAGGLDGWCL-CSLHGQQGIVPANRVKLLPA 68

Query: 62  PEPGPAGDGGPGAPARYANVPPGGFEPLPVAPPASFKPPPDAFQALLQPQQAPPPSTFQP 121
              GPA              P     P   A P S  P PD      +    PPP+    
Sbjct: 69  ---GPA--------------PKPSLSPASPAQPGSPYPAPDHSNEDQEVYVVPPPAR-PC 110

Query: 122 PGAGFPYGGGALQPSPQQLY 141
           P +G P   G   PSP  +Y
Sbjct: 111 PTSGPP--AGPCPPSPDLIY 128


>gi|4506929 SH3-domain GRB2-like 1 [Homo sapiens]
          Length = 368

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 25/54 (46%), Positives = 35/54 (64%), Gaps = 2/54 (3%)

Query: 6   RALYDFRSENPGEISLREHEVLSLCSEQDIEGWLEGVNSRGDRGLFPASYVQVI 59
           +ALYDF  EN GE+   E +V++L ++ D E W EG+   G  G FP SYV+V+
Sbjct: 312 KALYDFEPENDGELGFHEGDVITLTNQID-ENWYEGMLD-GQSGFFPLSYVEVL 363


>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
          Length = 522

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 72/291 (24%), Positives = 113/291 (38%), Gaps = 61/291 (20%)

Query: 268 EWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWL 319
           E QE+ +     I DP K     GM +Y++YK V T T +P        V RR+  F  L
Sbjct: 137 EEQEDQFDLTVGITDPEKIGD--GMNAYVAYK-VTTQTSLPLFRSKQFAVKRRFSDFLGL 193

Query: 320 YARLAEKFPV--ISVPHLPEKQATGRFE----------EDFISKRRKGLIWWMNHMASHP 367
           Y +L+EK       VP  PEK   G  +           +F+ KRR  L  ++  + +HP
Sbjct: 194 YEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHP 253

Query: 368 VLAQCDVFQHFLTCPSSTDEKAWKQGKRKAEKDEMVGANFFLTLSTPPAAALDLQEVESK 427
            + Q    + FL                  EK+E+  A    TLS    A L L+     
Sbjct: 254 TMLQDPDVREFL------------------EKEELPRAVGTQTLS---GAGL-LKMFNKA 291

Query: 428 IDGFKCFTKKMDDSALQLNHTANEFARKQ------------VTGFKKEYQ-KVGQSFRGL 474
            D     T KM++S +       E   ++            +   +KE      Q  + L
Sbjct: 292 TDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSL 351

Query: 475 SQAFELDQQAFSVGLNQAIAFTGDAYDAIGELFAEQPRQDLDPVMDLLALY 525
           +    L     +  L++A++   +  + I +L  EQ   D   + +LL+ Y
Sbjct: 352 AM---LGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDY 399


>gi|23111026 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 41/136 (30%), Positives = 57/136 (41%), Gaps = 11/136 (8%)

Query: 268 EWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWL 319
           E QE        + DP  Q +     SY+ YK+   HT           V RRY+ F WL
Sbjct: 9   ENQEQEEVITVRVQDPRVQNE-GSWNSYVDYKIF-LHTNSKAFTAKTSCVRRRYREFVWL 66

Query: 320 YARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFL 379
             +L     ++ VP LP K       ++FI KRR+GL  ++  +    VL        FL
Sbjct: 67  RKQLQRNAGLVPVPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFL 126

Query: 380 TCPSSTDE-KAWKQGK 394
               S  E +A  QG+
Sbjct: 127 QSQLSVPEIEACVQGR 142


>gi|23111028 sorting nexin 11 [Homo sapiens]
          Length = 270

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 41/136 (30%), Positives = 57/136 (41%), Gaps = 11/136 (8%)

Query: 268 EWQENPYPFQCTIDDPTKQTKFKGMKSYISYKLVPTHTQVP--------VHRRYKHFDWL 319
           E QE        + DP  Q +     SY+ YK+   HT           V RRY+ F WL
Sbjct: 9   ENQEQEEVITVRVQDPRVQNE-GSWNSYVDYKIF-LHTNSKAFTAKTSCVRRRYREFVWL 66

Query: 320 YARLAEKFPVISVPHLPEKQATGRFEEDFISKRRKGLIWWMNHMASHPVLAQCDVFQHFL 379
             +L     ++ VP LP K       ++FI KRR+GL  ++  +    VL        FL
Sbjct: 67  RKQLQRNAGLVPVPELPGKSTFFGTSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFL 126

Query: 380 TCPSSTDE-KAWKQGK 394
               S  E +A  QG+
Sbjct: 127 QSQLSVPEIEACVQGR 142


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,613,266
Number of Sequences: 37866
Number of extensions: 1710495
Number of successful extensions: 12012
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 193
Number of HSP's successfully gapped in prelim test: 721
Number of HSP's that attempted gapping in prelim test: 8356
Number of HSP's gapped (non-prelim): 3263
length of query: 624
length of database: 18,247,518
effective HSP length: 108
effective length of query: 516
effective length of database: 14,157,990
effective search space: 7305522840
effective search space used: 7305522840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.