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Search of human proteins with 11056038
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]
(365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11056038 visual system homeobox 1 isoform a [Homo sapiens] 745 0.0
gi|40806216 visual system homeobox 1 isoform b [Homo sapiens] 427 e-119
gi|34365783 visual system homeobox 2 [Homo sapiens] 236 2e-62
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 107 1e-23
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 107 2e-23
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 107 2e-23
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 106 4e-23
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 103 2e-22
gi|14149760 orthopedia homeobox [Homo sapiens] 103 2e-22
gi|24497589 aristaless related homeobox [Homo sapiens] 103 3e-22
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 102 5e-22
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 102 5e-22
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 102 5e-22
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap... 101 1e-21
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 100 2e-21
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 100 2e-21
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 100 2e-21
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 100 2e-21
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 100 2e-21
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 100 2e-21
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 100 3e-21
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 100 3e-21
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 100 3e-21
gi|12707580 paired-like homeobox 2b [Homo sapiens] 97 3e-20
gi|122937321 UNC homeobox [Homo sapiens] 95 9e-20
gi|46249382 paired-like homeobox 2a [Homo sapiens] 95 1e-19
gi|57232759 intestine-specific homeobox [Homo sapiens] 93 3e-19
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 92 7e-19
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 92 1e-18
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 91 2e-18
>gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]
Length = 365
Score = 745 bits (1923), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAV 60
MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAV
Sbjct: 1 MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAV 60
Query: 61 APCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPL 120
APCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPL
Sbjct: 61 APCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPL 120
Query: 121 APSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELE 180
APSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELE
Sbjct: 121 APSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELE 180
Query: 181 KAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGA 240
KAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGA
Sbjct: 181 KAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVMAEYGLYGA 240
Query: 241 MVRHCIPLPDSVLNSAEGGLLGSCAPWLLGMHKKSMGMIRKPGSEDKLAGLWGSDHFKEG 300
MVRHCIPLPDSVLNSAEGGLLGSCAPWLLGMHKKSMGMIRKPGSEDKLAGLWGSDHFKEG
Sbjct: 241 MVRHCIPLPDSVLNSAEGGLLGSCAPWLLGMHKKSMGMIRKPGSEDKLAGLWGSDHFKEG 300
Query: 301 SSQSESGSQRGSDKVSPENGLEDVAIDLSSSARQETKKVHPGAGAQGGSNSTALEGPQPG 360
SSQSESGSQRGSDKVSPENGLEDVAIDLSSSARQETKKVHPGAGAQGGSNSTALEGPQPG
Sbjct: 301 SSQSESGSQRGSDKVSPENGLEDVAIDLSSSARQETKKVHPGAGAQGGSNSTALEGPQPG 360
Query: 361 KVGAT 365
KVGAT
Sbjct: 361 KVGAT 365
>gi|40806216 visual system homeobox 1 isoform b [Homo sapiens]
Length = 239
Score = 427 bits (1097), Expect = e-119
Identities = 210/210 (100%), Positives = 210/210 (100%)
Query: 1 MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAV 60
MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAV
Sbjct: 1 MTGRDSLSDGRTSSRALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAV 60
Query: 61 APCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPL 120
APCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPL
Sbjct: 61 APCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPL 120
Query: 121 APSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELE 180
APSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELE
Sbjct: 121 APSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELE 180
Query: 181 KAFSEAHYPDVYAREMLAVKTELPEDRIQV 210
KAFSEAHYPDVYAREMLAVKTELPEDRIQV
Sbjct: 181 KAFSEAHYPDVYAREMLAVKTELPEDRIQV 210
>gi|34365783 visual system homeobox 2 [Homo sapiens]
Length = 361
Score = 236 bits (602), Expect = 2e-62
Identities = 166/372 (44%), Positives = 208/372 (55%), Gaps = 48/372 (12%)
Query: 1 MTGR--DSLSDGRTSSRAL-VPGGSPRGSRPRGFAITDLLGLEAELPAP----AGPGQGS 53
MTG+ ++LS ++ + A GG+P +R GF I ++LGL E P+ A G
Sbjct: 1 MTGKAGEALSKPKSETVAKSTSGGAP--ARCTGFGIQEILGLNKEPPSSHPRAALDGLAP 58
Query: 54 GCEGPAVAPCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRG 113
G A + G+ G L LG G L GF TQP FL
Sbjct: 59 GHLLAARSVLSPAGVGGMGL------LGPGGLPGFYTQPT--------------FLEVLS 98
Query: 114 PEPAAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPT-LGKRKKRRHRTVFT 172
+ L P A G S + S+ ED S DR K++ KRKKRRHRT+FT
Sbjct: 99 DPQSVHLQPLGR--ASGPLDTSQTASSDSEDVSSSDRKMSKSALNQTKKRKKRRHRTIFT 156
Query: 173 AHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGGSSVM 232
++QLEELEKAF+EAHYPDVYAREMLA+KTELPEDRIQVWFQNRRAKWRKREK WG SSVM
Sbjct: 157 SYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRAKWRKREKCWGRSSVM 216
Query: 233 AEYGLYGAMVRHCIPLPDSVLNSAEGGLLGSCAPWLLGMHKKSMGMIRKPG--SEDKLAG 290
AEYGLYGAMVRH IPLP+S+L SA+ G++ SCAPWLLGMHKKS+ + G E +
Sbjct: 217 AEYGLYGAMVRHSIPLPESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGERQA 276
Query: 291 LWGSDHFKEGSSQSESGSQRGSD---KVSPENGLEDVAIDLSSSARQETKKVHPGAGAQG 347
L D ++ +RG D +S E E+ L + A++ + KV G
Sbjct: 277 LPKLDKMEQ--------DERGPDAQAAISQEELRENSIAVLRAKAQEHSTKV---LGTVS 325
Query: 348 GSNSTALEGPQP 359
G +S A +P
Sbjct: 326 GPDSLARSTEKP 337
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 107 bits (268), Expect = 1e-23
Identities = 52/91 (57%), Positives = 62/91 (68%), Gaps = 1/91 (1%)
Query: 134 RSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYA 193
R V E + ++ D K + KKRRHRT FT+ QLEELEK F + HYPDVY
Sbjct: 103 RMSPVKGMQEKGELDELGD-KCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYV 161
Query: 194 REMLAVKTELPEDRIQVWFQNRRAKWRKREK 224
RE LA++TEL E R+QVWFQNRRAKWRKRE+
Sbjct: 162 REQLALRTELTEARVQVWFQNRRAKWRKRER 192
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 107 bits (267), Expect = 2e-23
Identities = 49/71 (69%), Positives = 58/71 (81%)
Query: 154 KASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQ 213
KA K KKRR+RT FT++QLEELEK F + HYPDVYARE LA++T+L E R+QVWFQ
Sbjct: 204 KADSESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQ 263
Query: 214 NRRAKWRKREK 224
NRRAKWRKRE+
Sbjct: 264 NRRAKWRKRER 274
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 107 bits (266), Expect = 2e-23
Identities = 82/209 (39%), Positives = 93/209 (44%), Gaps = 45/209 (21%)
Query: 23 PRGSRPRGFAITDLLGLEAELPAPAGPG----QGSGCEGPAVAPCPGPGLDGSSLARGAL 78
PRG R F LE LP PA P Q G PGP L+G G
Sbjct: 43 PRGPRLTRFPACG--PLEPYLPEPAKPPAKYLQDLG---------PGPALNGGHFYEG-- 89
Query: 79 PLGLGLLCGFGTQPPAAARAPCLLLADVPFLP---PRGPEPAAPLAPSRPPPALGRQKRS 135
PA A A P LP GP P P L
Sbjct: 90 --------------PAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLP 135
Query: 136 DSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYARE 195
+S DS +N K KKRR+RT F+ QLEELEK F + HYPDVYARE
Sbjct: 136 --LSPGLPDSMELAKN---------KSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYARE 184
Query: 196 MLAVKTELPEDRIQVWFQNRRAKWRKREK 224
LA++T+L E R+QVWFQNRRAKWRKRE+
Sbjct: 185 QLALRTDLTEARVQVWFQNRRAKWRKRER 213
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 106 bits (264), Expect = 4e-23
Identities = 57/128 (44%), Positives = 73/128 (57%), Gaps = 15/128 (11%)
Query: 107 PFLPPRGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLG------ 160
P P G EP+ P AP+ P + + E ++ L P G
Sbjct: 74 PKAPEEGSEPSPPPAPAPAP-----EYEAPRPYCPKEPGEARPSPGLPVGPATGEAKLSE 128
Query: 161 ----KRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRR 216
K+K RR+RT FT +QL ELE+AF ++HYPDVY+RE LA K LPE R+QVWFQNRR
Sbjct: 129 EEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQVWFQNRR 188
Query: 217 AKWRKREK 224
AKWR++EK
Sbjct: 189 AKWRRQEK 196
Score = 34.7 bits (78), Expect = 0.14
Identities = 31/93 (33%), Positives = 34/93 (36%), Gaps = 22/93 (23%)
Query: 44 PAPAGPGQGSGCEGPAV-------APCPGPGLDGSSLARGALPLGLGLLCGFGTQPPAAA 96
P AGPG G G G A+ P PG G G P L + PP
Sbjct: 223 PLGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPPP- 281
Query: 97 RAPCLLLADVPFL--PPRGP--EPAAPLAPSRP 125
PFL PP GP +P AP PS P
Sbjct: 282 ----------PFLNSPPLGPGLQPLAPPPPSYP 304
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 103 bits (258), Expect = 2e-22
Identities = 53/118 (44%), Positives = 72/118 (61%), Gaps = 3/118 (2%)
Query: 110 PPRGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDR---NDLKASPTLGKRKKRR 166
P P A L P +G S +VS D D Q + N +A G++K++R
Sbjct: 47 PNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKR 106
Query: 167 HRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK 224
HRT FT QL ELE++F++ HYPD++ RE LA++ L E R+QVWFQNRRAKW+KR+K
Sbjct: 107 HRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKK 164
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 103 bits (258), Expect = 2e-22
Identities = 53/118 (44%), Positives = 72/118 (61%), Gaps = 3/118 (2%)
Query: 110 PPRGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDSQSEDR---NDLKASPTLGKRKKRR 166
P P A L P +G S +VS D D Q + N +A G++K++R
Sbjct: 47 PNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQPGPQGGPNPSQAGQQQGQQKQKR 106
Query: 167 HRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK 224
HRT FT QL ELE++F++ HYPD++ RE LA++ L E R+QVWFQNRRAKW+KR+K
Sbjct: 107 HRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAKWKKRKK 164
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 103 bits (256), Expect = 3e-22
Identities = 50/89 (56%), Positives = 65/89 (73%), Gaps = 7/89 (7%)
Query: 143 EDSQSEDRNDL-------KASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYARE 195
ED++ +D D + L KRK+RR+RT FT++QLEELE+AF + HYPDV+ RE
Sbjct: 300 EDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTRE 359
Query: 196 MLAVKTELPEDRIQVWFQNRRAKWRKREK 224
LA++ +L E R+QVWFQNRRAKWRKREK
Sbjct: 360 ELAMRLDLTEARVQVWFQNRRAKWRKREK 388
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 102 bits (254), Expect = 5e-22
Identities = 50/96 (52%), Positives = 68/96 (70%), Gaps = 3/96 (3%)
Query: 130 GRQKRSDSVS--TSDEDSQSEDRNDLKASPTLG-KRKKRRHRTVFTAHQLEELEKAFSEA 186
G +K S+ D+ ++ ++ +D+++ P L KRK+RR RT FTA QLEELEKAF
Sbjct: 180 GEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERT 239
Query: 187 HYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKR 222
HYPD+Y RE LA +T+L E R+QVWF NRRA+WRK+
Sbjct: 240 HYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 275
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 102 bits (254), Expect = 5e-22
Identities = 50/96 (52%), Positives = 68/96 (70%), Gaps = 3/96 (3%)
Query: 130 GRQKRSDSVS--TSDEDSQSEDRNDLKASPTLG-KRKKRRHRTVFTAHQLEELEKAFSEA 186
G +K S+ D+ ++ ++ +D+++ P L KRK+RR RT FTA QLEELEKAF
Sbjct: 178 GEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERT 237
Query: 187 HYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKR 222
HYPD+Y RE LA +T+L E R+QVWF NRRA+WRK+
Sbjct: 238 HYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 273
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 102 bits (254), Expect = 5e-22
Identities = 50/96 (52%), Positives = 68/96 (70%), Gaps = 3/96 (3%)
Query: 130 GRQKRSDSVS--TSDEDSQSEDRNDLKASPTLG-KRKKRRHRTVFTAHQLEELEKAFSEA 186
G +K S+ D+ ++ ++ +D+++ P L KRK+RR RT FTA QLEELEKAF
Sbjct: 180 GEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERT 239
Query: 187 HYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKR 222
HYPD+Y RE LA +T+L E R+QVWF NRRA+WRK+
Sbjct: 240 HYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ 275
>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
sapiens]
Length = 184
Score = 101 bits (251), Expect = 1e-21
Identities = 45/73 (61%), Positives = 57/73 (78%)
Query: 161 KRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWR 220
K+K RR+RT FT +QL +LE+AF +HYPDVY+RE LA K LPE R+QVWFQNRRAKWR
Sbjct: 24 KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
Query: 221 KREKRWGGSSVMA 233
++E+ GS +A
Sbjct: 84 RQERLESGSGAVA 96
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 100 bits (250), Expect = 2e-21
Identities = 57/125 (45%), Positives = 76/125 (60%), Gaps = 6/125 (4%)
Query: 112 RGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDS--QSEDRNDLKASPTLG-KRKKRRHR 168
+G E A L + + K S S+ S QS++ +D+ + P L KRK+RR R
Sbjct: 163 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 222
Query: 169 TVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGG 228
T FTA QLEELE+AF HYPD+Y RE LA + +L E R+QVWF NRRA+WRK+ G
Sbjct: 223 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA---GA 279
Query: 229 SSVMA 233
+ +MA
Sbjct: 280 NQLMA 284
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 100 bits (250), Expect = 2e-21
Identities = 57/125 (45%), Positives = 76/125 (60%), Gaps = 6/125 (4%)
Query: 112 RGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDS--QSEDRNDLKASPTLG-KRKKRRHR 168
+G E A L + + K S S+ S QS++ +D+ + P L KRK+RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223
Query: 169 TVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGG 228
T FTA QLEELE+AF HYPD+Y RE LA + +L E R+QVWF NRRA+WRK+ G
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA---GA 280
Query: 229 SSVMA 233
+ +MA
Sbjct: 281 NQLMA 285
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 100 bits (250), Expect = 2e-21
Identities = 57/125 (45%), Positives = 76/125 (60%), Gaps = 6/125 (4%)
Query: 112 RGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDS--QSEDRNDLKASPTLG-KRKKRRHR 168
+G E A L + + K S S+ S QS++ +D+ + P L KRK+RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223
Query: 169 TVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGG 228
T FTA QLEELE+AF HYPD+Y RE LA + +L E R+QVWF NRRA+WRK+ G
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA---GA 280
Query: 229 SSVMA 233
+ +MA
Sbjct: 281 NQLMA 285
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 100 bits (250), Expect = 2e-21
Identities = 57/125 (45%), Positives = 76/125 (60%), Gaps = 6/125 (4%)
Query: 112 RGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDS--QSEDRNDLKASPTLG-KRKKRRHR 168
+G E A L + + K S S+ S QS++ +D+ + P L KRK+RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223
Query: 169 TVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGG 228
T FTA QLEELE+AF HYPD+Y RE LA + +L E R+QVWF NRRA+WRK+ G
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA---GA 280
Query: 229 SSVMA 233
+ +MA
Sbjct: 281 NQLMA 285
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 100 bits (250), Expect = 2e-21
Identities = 57/125 (45%), Positives = 76/125 (60%), Gaps = 6/125 (4%)
Query: 112 RGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDS--QSEDRNDLKASPTLG-KRKKRRHR 168
+G E A L + + K S S+ S QS++ +D+ + P L KRK+RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223
Query: 169 TVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGG 228
T FTA QLEELE+AF HYPD+Y RE LA + +L E R+QVWF NRRA+WRK+ G
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA---GA 280
Query: 229 SSVMA 233
+ +MA
Sbjct: 281 NQLMA 285
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 100 bits (250), Expect = 2e-21
Identities = 57/125 (45%), Positives = 76/125 (60%), Gaps = 6/125 (4%)
Query: 112 RGPEPAAPLAPSRPPPALGRQKRSDSVSTSDEDS--QSEDRNDLKASPTLG-KRKKRRHR 168
+G E A L + + K S S+ S QS++ +D+ + P L KRK+RR R
Sbjct: 164 KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDLPLKRKQRRSR 223
Query: 169 TVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREKRWGG 228
T FTA QLEELE+AF HYPD+Y RE LA + +L E R+QVWF NRRA+WRK+ G
Sbjct: 224 TTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA---GA 280
Query: 229 SSVMA 233
+ +MA
Sbjct: 281 NQLMA 285
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 100 bits (248), Expect = 3e-21
Identities = 61/149 (40%), Positives = 83/149 (55%), Gaps = 9/149 (6%)
Query: 122 PSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEK 181
P +P +Q+ +T+ S ED ++ + L KRK +R+RT FT Q+E LEK
Sbjct: 169 PGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQL-KRKLQRNRTSFTQEQIEALEK 227
Query: 182 AFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK----RWGGSSVMAEYGL 237
F HYPDV+ARE LA K +LPE RIQVWF NRRAKWR+ EK R S+ + +
Sbjct: 228 EFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPI 287
Query: 238 ---YGAMVRHCIPLPDSVLNS-AEGGLLG 262
+ V IP P + ++S G +LG
Sbjct: 288 SSSFSTSVYQPIPQPTTPVSSFTSGSMLG 316
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 100 bits (248), Expect = 3e-21
Identities = 61/149 (40%), Positives = 83/149 (55%), Gaps = 9/149 (6%)
Query: 122 PSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEK 181
P +P +Q+ +T+ S ED ++ + L KRK +R+RT FT Q+E LEK
Sbjct: 183 PGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQL-KRKLQRNRTSFTQEQIEALEK 241
Query: 182 AFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK----RWGGSSVMAEYGL 237
F HYPDV+ARE LA K +LPE RIQVWF NRRAKWR+ EK R S+ + +
Sbjct: 242 EFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPI 301
Query: 238 ---YGAMVRHCIPLPDSVLNS-AEGGLLG 262
+ V IP P + ++S G +LG
Sbjct: 302 SSSFSTSVYQPIPQPTTPVSSFTSGSMLG 330
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 100 bits (248), Expect = 3e-21
Identities = 61/149 (40%), Positives = 83/149 (55%), Gaps = 9/149 (6%)
Query: 122 PSRPPPALGRQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFTAHQLEELEK 181
P +P +Q+ +T+ S ED ++ + L KRK +R+RT FT Q+E LEK
Sbjct: 169 PGQPTQDGCQQQEGGGENTNSISSNGEDSDEAQMRLQL-KRKLQRNRTSFTQEQIEALEK 227
Query: 182 AFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK----RWGGSSVMAEYGL 237
F HYPDV+ARE LA K +LPE RIQVWF NRRAKWR+ EK R S+ + +
Sbjct: 228 EFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPI 287
Query: 238 ---YGAMVRHCIPLPDSVLNS-AEGGLLG 262
+ V IP P + ++S G +LG
Sbjct: 288 SSSFSTSVYQPIPQPTTPVSSFTSGSMLG 316
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 96.7 bits (239), Expect = 3e-20
Identities = 45/79 (56%), Positives = 60/79 (75%)
Query: 161 KRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWR 220
KRK+RR RT FT+ QL+ELE+ F+E HYPD+Y RE LA+K +L E R+QVWFQNRRAK+R
Sbjct: 95 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 154
Query: 221 KREKRWGGSSVMAEYGLYG 239
K+E+ ++ A+ G G
Sbjct: 155 KQERAAAAAAAAAKNGSSG 173
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 95.1 bits (235), Expect = 9e-20
Identities = 43/61 (70%), Positives = 52/61 (85%)
Query: 163 KKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKR 222
K+RR RT FT QLEELEKAF+E+HYPDV+ RE LA++ +L E R+QVWFQNRRAKWRK+
Sbjct: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
Query: 223 E 223
E
Sbjct: 164 E 164
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 94.7 bits (234), Expect = 1e-19
Identities = 52/119 (43%), Positives = 66/119 (55%), Gaps = 11/119 (9%)
Query: 161 KRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWR 220
KRK+RR RT FT+ QL+ELE+ F+E HYPD+Y RE LA+K +L E R+QVWFQNRRAK+R
Sbjct: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
Query: 221 KREKRWGGSSVMAEYGLYGAMVR-----------HCIPLPDSVLNSAEGGLLGSCAPWL 268
K+E+ G R C P PDS + G +P L
Sbjct: 147 KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRL 205
>gi|57232759 intestine-specific homeobox [Homo sapiens]
Length = 245
Score = 93.2 bits (230), Expect = 3e-19
Identities = 42/71 (59%), Positives = 50/71 (70%)
Query: 154 KASPTLGKRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQ 213
K P G++ KRR RT FT QL ELEK F HYPDV+ R LA + LPE R+Q+WFQ
Sbjct: 72 KDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQ 131
Query: 214 NRRAKWRKREK 224
N+RAKWRK+EK
Sbjct: 132 NQRAKWRKQEK 142
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 92.0 bits (227), Expect = 7e-19
Identities = 41/64 (64%), Positives = 50/64 (78%)
Query: 161 KRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWR 220
+RK+RR+RT FT QLE LE F++ HYPDV+ RE LA+K L E R+QVWFQNRRAKWR
Sbjct: 35 RRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWR 94
Query: 221 KREK 224
K E+
Sbjct: 95 KTER 98
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 91.7 bits (226), Expect = 1e-18
Identities = 49/112 (43%), Positives = 65/112 (58%), Gaps = 2/112 (1%)
Query: 114 PEPAAPLAPSRPPPALG-RQKRSDSVSTSDEDSQSEDRNDLKASPTLGKRKKRRHRTVFT 172
P P PP L +Q++ + T+ E Q + P +RK+RR RT FT
Sbjct: 89 PPLTKPEQQQEEPPLLELKQEQEEPPQTTVEGPQPAEGPQTAEGPQPPERKRRR-RTAFT 147
Query: 173 AHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRKREK 224
QL+ELE F E+ YPDV ARE LA + L EDR+QVWFQNRRAKW++ ++
Sbjct: 148 QFQLQELENFFDESQYPDVVARERLAARLNLTEDRVQVWFQNRRAKWKRNQR 199
Score = 33.5 bits (75), Expect = 0.31
Identities = 35/116 (30%), Positives = 43/116 (37%), Gaps = 17/116 (14%)
Query: 16 ALVPGGSPRGSRPRGFAITDLLGLEAELPAPAGPGQGSGCEGPAVAPCP-GPGL----DG 70
A VP GS P G + + P P P GP +AP P GP + G
Sbjct: 274 APVPPGSRMAPVPPGPRMAPVPPWPPMAPVPPWPPMAPVPTGPPMAPVPPGPPMARVPPG 333
Query: 71 SSLARGALPLGLGLLCGFGTQPPAAARAPCLLLADVPFLPPRGPEPAAPLAPSRPP 126
+AR +P G PP A P +A +P PP P P P PP
Sbjct: 334 PPMAR--VPPG----------PPMAPLPPGPPMAPLPPGPPMAPLPPGPPMAPLPP 377
Score = 29.3 bits (64), Expect = 5.8
Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 6/91 (6%)
Query: 44 PAPAGPGQGSGCEGPAVAPCP--GPGLDGSSLARGALPLGLGLLCGFGTQPPAAARAPCL 101
P P P P +AP P P GS +A +P G + PP A P
Sbjct: 251 PMPPRPPMVPMPPRPPIAPMPPMAPVPPGSRMA--PVPPG-PRMAPVPPWPPMAPVPPWP 307
Query: 102 LLADVPFLPPRGP-EPAAPLAPSRPPPALGR 131
+A VP PP P P P+A P P + R
Sbjct: 308 PMAPVPTGPPMAPVPPGPPMARVPPGPPMAR 338
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 90.5 bits (223), Expect = 2e-18
Identities = 71/200 (35%), Positives = 95/200 (47%), Gaps = 23/200 (11%)
Query: 162 RKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWRK 221
RK+RR RT FTA QLE LEK F + HYPDV RE LA+ T LPE R+QVWF+NRRAK+RK
Sbjct: 69 RKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRK 128
Query: 222 REKRWGGSSVMAEYGLYGA--MVRHCIPLPDSVLNSAEGGLL-GSCAPWLLGMH------ 272
+++ + + G+ + P PD+ L++ + L GS P L +
Sbjct: 129 KQRSLQKEQLQKQKEAEGSHGEGKAEAPTPDTQLDTEQPPRLPGSDPPAELHLSLSEQSA 188
Query: 273 KKSMGMIRKPGSEDKLAGLWGSDHFKEGSSQSES-GSQRGSDKVSPENGLEDVAIDLSSS 331
+S + ED AG K + S+ G +RGS K L
Sbjct: 189 SESAPEDQPDREEDPRAGAEDPKAEKSPGADSKGLGCKRGSPKADSPGSL---------- 238
Query: 332 ARQETKKVHPGAGAQGGSNS 351
V PG G G S+S
Sbjct: 239 ---TITPVAPGGGLLGPSHS 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.133 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,091,741
Number of Sequences: 37866
Number of extensions: 1118487
Number of successful extensions: 8622
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 374
Number of HSP's successfully gapped in prelim test: 489
Number of HSP's that attempted gapping in prelim test: 6725
Number of HSP's gapped (non-prelim): 2125
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.