Guide to the Human Genome
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Search of human proteins with 110349786

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110349786 Alstrom syndrome 1 [Homo sapiens]
         (4169 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110349786 Alstrom syndrome 1 [Homo sapiens]                       8319   0.0  
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       124   2e-27
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                       112   8e-24
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...   100   2e-20
gi|91982772 mucin 17 [Homo sapiens]                                    98   1e-19
gi|52145312 hypothetical protein LOC118611 [Homo sapiens]              97   4e-19
gi|83367077 mucin 16 [Homo sapiens]                                    87   3e-16
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        73   5e-12
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                        73   5e-12
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    72   1e-11
gi|151301154 mucin 6, gastric [Homo sapiens]                           70   3e-11
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             69   1e-10
gi|89026265 PREDICTED: mucin 12 [Homo sapiens]                         62   1e-08
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             58   2e-07
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]               57   3e-07
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]               57   3e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    55   1e-06
gi|150170670 piccolo isoform 2 [Homo sapiens]                          55   2e-06
gi|150378539 piccolo isoform 1 [Homo sapiens]                          55   2e-06
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]     53   6e-06
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]     53   7e-06
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]     53   7e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   52   9e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   52   9e-06
gi|161019170 mucin 5AC [Homo sapiens]                                  52   1e-05
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       52   1e-05
gi|30089948 protein phosphatase 1E [Homo sapiens]                      52   1e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    52   2e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                        51   2e-05
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...    50   4e-05

>gi|110349786 Alstrom syndrome 1 [Homo sapiens]
          Length = 4169

 Score = 8319 bits (21585), Expect = 0.0
 Identities = 4169/4169 (100%), Positives = 4169/4169 (100%)

Query: 1    MEPEDLPWPGELEEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSDSH 60
            MEPEDLPWPGELEEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSDSH
Sbjct: 1    MEPEDLPWPGELEEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSDSH 60

Query: 61   YGPQHLESIDDEEDEEAKAWLQAHPGRILPPLSPPQHRYSEGERTSLEKIVPLTCHVWQQ 120
            YGPQHLESIDDEEDEEAKAWLQAHPGRILPPLSPPQHRYSEGERTSLEKIVPLTCHVWQQ
Sbjct: 61   YGPQHLESIDDEEDEEAKAWLQAHPGRILPPLSPPQHRYSEGERTSLEKIVPLTCHVWQQ 120

Query: 121  IVYQGNSRTQISDTNVVCLETTAQRGSGDDQKTESWHCLPQEMDSSQTLDTSQTRFNVRT 180
            IVYQGNSRTQISDTNVVCLETTAQRGSGDDQKTESWHCLPQEMDSSQTLDTSQTRFNVRT
Sbjct: 121  IVYQGNSRTQISDTNVVCLETTAQRGSGDDQKTESWHCLPQEMDSSQTLDTSQTRFNVRT 180

Query: 181  EDTEVTDFPSLEEGILTQSENQVKEPNRDLFCSPLLVIQDSFASPDLPLLTCLTQDQEFA 240
            EDTEVTDFPSLEEGILTQSENQVKEPNRDLFCSPLLVIQDSFASPDLPLLTCLTQDQEFA
Sbjct: 181  EDTEVTDFPSLEEGILTQSENQVKEPNRDLFCSPLLVIQDSFASPDLPLLTCLTQDQEFA 240

Query: 241  PDSLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSRFSVSQHP 300
            PDSLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSRFSVSQHP
Sbjct: 241  PDSLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQATAEVASDLASSRFSVSQHP 300

Query: 301  LIGSTAVGSQCPFLPSEQGNNEETISSVDELKIPKDCDRYDDLCSYMSWKTRKDTQWPEN 360
            LIGSTAVGSQCPFLPSEQGNNEETISSVDELKIPKDCDRYDDLCSYMSWKTRKDTQWPEN
Sbjct: 301  LIGSTAVGSQCPFLPSEQGNNEETISSVDELKIPKDCDRYDDLCSYMSWKTRKDTQWPEN 360

Query: 361  NLADKDQVSVATSFDITDENIATKRSDHFDAARSYGQYWTQEDSSKQAETYLTKGLQGKV 420
            NLADKDQVSVATSFDITDENIATKRSDHFDAARSYGQYWTQEDSSKQAETYLTKGLQGKV
Sbjct: 361  NLADKDQVSVATSFDITDENIATKRSDHFDAARSYGQYWTQEDSSKQAETYLTKGLQGKV 420

Query: 421  ESDVITLDGLNENAVVCSERVAELQRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKAGD 480
            ESDVITLDGLNENAVVCSERVAELQRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKAGD
Sbjct: 421  ESDVITLDGLNENAVVCSERVAELQRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKAGD 480

Query: 481  TSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQ 540
            TSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQ
Sbjct: 481  TSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQ 540

Query: 541  KTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEAL 600
            KTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEAL
Sbjct: 541  KTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEAL 600

Query: 601  KVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKT 660
            KVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKT
Sbjct: 601  KVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKT 660

Query: 661  GIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHR 720
            GIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHR
Sbjct: 661  GIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHR 720

Query: 721  EKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLA 780
            EKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLA
Sbjct: 721  EKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLA 780

Query: 781  DSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSA 840
            DSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSA
Sbjct: 781  DSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSA 840

Query: 841  VSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTG 900
            VSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTG
Sbjct: 841  VSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTG 900

Query: 901  IPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSE 960
            IPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSE
Sbjct: 901  IPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSE 960

Query: 961  KSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPD 1020
            KSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPD
Sbjct: 961  KSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPD 1020

Query: 1021 SYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAF 1080
            SYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAF
Sbjct: 1021 SYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAF 1080

Query: 1081 PGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTV 1140
            PGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTV
Sbjct: 1081 PGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTV 1140

Query: 1141 TSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPG 1200
            TSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPG
Sbjct: 1141 TSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPG 1200

Query: 1201 IFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPT 1260
            IFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPT
Sbjct: 1201 IFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPT 1260

Query: 1261 EEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGP 1320
            EEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGP
Sbjct: 1261 EEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGP 1320

Query: 1321 ADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTST 1380
            ADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTST
Sbjct: 1321 ADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTST 1380

Query: 1381 SYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFY 1440
            SYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFY
Sbjct: 1381 SYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFY 1440

Query: 1441 QQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEES 1500
            QQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEES
Sbjct: 1441 QQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEES 1500

Query: 1501 LKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQ 1560
            LKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQ
Sbjct: 1501 LKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQ 1560

Query: 1561 TTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSA 1620
            TTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSA
Sbjct: 1561 TTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSA 1620

Query: 1621 LGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTL 1680
            LGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTL
Sbjct: 1621 LGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTL 1680

Query: 1681 SDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVS 1740
            SDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVS
Sbjct: 1681 SDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVS 1740

Query: 1741 AVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVS 1800
            AVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVS
Sbjct: 1741 AVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVS 1800

Query: 1801 TVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVI 1860
            TVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVI
Sbjct: 1801 TVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVI 1860

Query: 1861 SYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALN 1920
            SYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALN
Sbjct: 1861 SYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALN 1920

Query: 1921 VFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTG 1980
            VFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTG
Sbjct: 1921 VFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTG 1980

Query: 1981 IPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTP 2040
            IPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTP
Sbjct: 1981 IPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTP 2040

Query: 2041 SQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVNTGKPVSLSSSYFHRE 2100
            SQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVNTGKPVSLSSSYFHRE
Sbjct: 2041 SQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVNTGKPVSLSSSYFHRE 2100

Query: 2101 KSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDR 2160
            KSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDR
Sbjct: 2101 KSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDR 2160

Query: 2161 HLTEDALKISSALGQADQITGLQTVPSGTYSHGENHKLVSEHVQRLIDNLNSSDSSVSSN 2220
            HLTEDALKISSALGQADQITGLQTVPSGTYSHGENHKLVSEHVQRLIDNLNSSDSSVSSN
Sbjct: 2161 HLTEDALKISSALGQADQITGLQTVPSGTYSHGENHKLVSEHVQRLIDNLNSSDSSVSSN 2220

Query: 2221 NVLLNSQADDRVVINKPESAGFRDVGSEEIQDAENSAKTLKEIRTLLMEAENMALKRCNF 2280
            NVLLNSQADDRVVINKPESAGFRDVGSEEIQDAENSAKTLKEIRTLLMEAENMALKRCNF
Sbjct: 2221 NVLLNSQADDRVVINKPESAGFRDVGSEEIQDAENSAKTLKEIRTLLMEAENMALKRCNF 2280

Query: 2281 PAPLARFRDISDISFIQSKKVVCFKEPSSTGVSNGDLLHRQPFTEESPSSRCIQKDIGTQ 2340
            PAPLARFRDISDISFIQSKKVVCFKEPSSTGVSNGDLLHRQPFTEESPSSRCIQKDIGTQ
Sbjct: 2281 PAPLARFRDISDISFIQSKKVVCFKEPSSTGVSNGDLLHRQPFTEESPSSRCIQKDIGTQ 2340

Query: 2341 TNLKCRRGIENWEFISSTTVRSPLQEAESKVSMALEETLRQYQAAKSVMRSEPEGCSGTI 2400
            TNLKCRRGIENWEFISSTTVRSPLQEAESKVSMALEETLRQYQAAKSVMRSEPEGCSGTI
Sbjct: 2341 TNLKCRRGIENWEFISSTTVRSPLQEAESKVSMALEETLRQYQAAKSVMRSEPEGCSGTI 2400

Query: 2401 GNKIIIPMMTVIKSDSSSDASDGNGSCSWDSNLPESLESVSDVLLNFFPYVSPKTSITDS 2460
            GNKIIIPMMTVIKSDSSSDASDGNGSCSWDSNLPESLESVSDVLLNFFPYVSPKTSITDS
Sbjct: 2401 GNKIIIPMMTVIKSDSSSDASDGNGSCSWDSNLPESLESVSDVLLNFFPYVSPKTSITDS 2460

Query: 2461 REEEGVSESEDGGGSSVDSLAAHVKNLLQCESSLNHAKEILRNAEEEESRVRAHAWNMKF 2520
            REEEGVSESEDGGGSSVDSLAAHVKNLLQCESSLNHAKEILRNAEEEESRVRAHAWNMKF
Sbjct: 2461 REEEGVSESEDGGGSSVDSLAAHVKNLLQCESSLNHAKEILRNAEEEESRVRAHAWNMKF 2520

Query: 2521 NLAHDCGYSISELNEDDRRKVEEIKAELFGHGRTTDLSKGLQSPRGMGCKPEAVCSHIII 2580
            NLAHDCGYSISELNEDDRRKVEEIKAELFGHGRTTDLSKGLQSPRGMGCKPEAVCSHIII
Sbjct: 2521 NLAHDCGYSISELNEDDRRKVEEIKAELFGHGRTTDLSKGLQSPRGMGCKPEAVCSHIII 2580

Query: 2581 ESHEKGCFRTLTSEHPQLDRHPCAFRSAGPSEMTRGRQNPSSCRAKHVNLSASLDQNNSH 2640
            ESHEKGCFRTLTSEHPQLDRHPCAFRSAGPSEMTRGRQNPSSCRAKHVNLSASLDQNNSH
Sbjct: 2581 ESHEKGCFRTLTSEHPQLDRHPCAFRSAGPSEMTRGRQNPSSCRAKHVNLSASLDQNNSH 2640

Query: 2641 FKVWNSLQLKSHSPFQNFIPDEFKISKGLRMPFDEKMDPWLSELVEPAFVPPKEVDFHSS 2700
            FKVWNSLQLKSHSPFQNFIPDEFKISKGLRMPFDEKMDPWLSELVEPAFVPPKEVDFHSS
Sbjct: 2641 FKVWNSLQLKSHSPFQNFIPDEFKISKGLRMPFDEKMDPWLSELVEPAFVPPKEVDFHSS 2700

Query: 2701 SQMPSPEPMKKFTTSITFSSHRHSKCISNSSVVKVGVTEGSQCTGASVGVFNSHFTEEQN 2760
            SQMPSPEPMKKFTTSITFSSHRHSKCISNSSVVKVGVTEGSQCTGASVGVFNSHFTEEQN
Sbjct: 2701 SQMPSPEPMKKFTTSITFSSHRHSKCISNSSVVKVGVTEGSQCTGASVGVFNSHFTEEQN 2760

Query: 2761 PPRDLKQKTSSPSSFKMHSNSQDKEVTILAEGRRQSQKLPVDFERSFQEEKPLERSDFTG 2820
            PPRDLKQKTSSPSSFKMHSNSQDKEVTILAEGRRQSQKLPVDFERSFQEEKPLERSDFTG
Sbjct: 2761 PPRDLKQKTSSPSSFKMHSNSQDKEVTILAEGRRQSQKLPVDFERSFQEEKPLERSDFTG 2820

Query: 2821 SHSEPSTRANCSNFKEIQISDNHTLISMGRPSSTLGVNRSSSRLGVKEKNVTITPDLPSC 2880
            SHSEPSTRANCSNFKEIQISDNHTLISMGRPSSTLGVNRSSSRLGVKEKNVTITPDLPSC
Sbjct: 2821 SHSEPSTRANCSNFKEIQISDNHTLISMGRPSSTLGVNRSSSRLGVKEKNVTITPDLPSC 2880

Query: 2881 IFLEQRELFEQSKAPRADDHVRKHHSPSPQHQDYVAPDLPSCIFLEQRELFEQCKAPYVD 2940
            IFLEQRELFEQSKAPRADDHVRKHHSPSPQHQDYVAPDLPSCIFLEQRELFEQCKAPYVD
Sbjct: 2881 IFLEQRELFEQSKAPRADDHVRKHHSPSPQHQDYVAPDLPSCIFLEQRELFEQCKAPYVD 2940

Query: 2941 HQMRENHSPLPQGQDSIASDLPSPISLEQCQSKAPGVDDQMNKHHFPLPQGQDCVVEKNN 3000
            HQMRENHSPLPQGQDSIASDLPSPISLEQCQSKAPGVDDQMNKHHFPLPQGQDCVVEKNN
Sbjct: 2941 HQMRENHSPLPQGQDSIASDLPSPISLEQCQSKAPGVDDQMNKHHFPLPQGQDCVVEKNN 3000

Query: 3001 QHKPKSHISNINVEAKFNTVVSQSAPNHCTLAASASTPPSNRKALSCVHITLCPKTSSKL 3060
            QHKPKSHISNINVEAKFNTVVSQSAPNHCTLAASASTPPSNRKALSCVHITLCPKTSSKL
Sbjct: 3001 QHKPKSHISNINVEAKFNTVVSQSAPNHCTLAASASTPPSNRKALSCVHITLCPKTSSKL 3060

Query: 3061 DSGTLDERFHSLDAASKARMNSEFNFDLHTVSSRSLEPTSKLLTSKPVAQDQESLGFLGP 3120
            DSGTLDERFHSLDAASKARMNSEFNFDLHTVSSRSLEPTSKLLTSKPVAQDQESLGFLGP
Sbjct: 3061 DSGTLDERFHSLDAASKARMNSEFNFDLHTVSSRSLEPTSKLLTSKPVAQDQESLGFLGP 3120

Query: 3121 KSSLDFQVVQPSLPDSNTITQDLKTIPSQNSQIVTSRQIQVNISDFEGHSNPEGTPVFAD 3180
            KSSLDFQVVQPSLPDSNTITQDLKTIPSQNSQIVTSRQIQVNISDFEGHSNPEGTPVFAD
Sbjct: 3121 KSSLDFQVVQPSLPDSNTITQDLKTIPSQNSQIVTSRQIQVNISDFEGHSNPEGTPVFAD 3180

Query: 3181 RLPEKMKTPLSAFSEKLSSDAVTQITTESPEKTLFSSEIFINAEDRGHEIIEPGNQKLRK 3240
            RLPEKMKTPLSAFSEKLSSDAVTQITTESPEKTLFSSEIFINAEDRGHEIIEPGNQKLRK
Sbjct: 3181 RLPEKMKTPLSAFSEKLSSDAVTQITTESPEKTLFSSEIFINAEDRGHEIIEPGNQKLRK 3240

Query: 3241 APVKFASSSSVQQVTFSRGTDGQPLLLPYKPSGSTKMYYVPQLRQIPPSPDSKSDTTVES 3300
            APVKFASSSSVQQVTFSRGTDGQPLLLPYKPSGSTKMYYVPQLRQIPPSPDSKSDTTVES
Sbjct: 3241 APVKFASSSSVQQVTFSRGTDGQPLLLPYKPSGSTKMYYVPQLRQIPPSPDSKSDTTVES 3300

Query: 3301 SHSGSNDAIAPDFPAQVLGTRDDDLSATVNIKHKEGIYSKRVVTKASLPVGEKPLQNENA 3360
            SHSGSNDAIAPDFPAQVLGTRDDDLSATVNIKHKEGIYSKRVVTKASLPVGEKPLQNENA
Sbjct: 3301 SHSGSNDAIAPDFPAQVLGTRDDDLSATVNIKHKEGIYSKRVVTKASLPVGEKPLQNENA 3360

Query: 3361 DASVQVLITGDENLSDKKQQEIHSTRAVTEAAQAKEKESLQKDTADSSAAAAAEHSAQVG 3420
            DASVQVLITGDENLSDKKQQEIHSTRAVTEAAQAKEKESLQKDTADSSAAAAAEHSAQVG
Sbjct: 3361 DASVQVLITGDENLSDKKQQEIHSTRAVTEAAQAKEKESLQKDTADSSAAAAAEHSAQVG 3420

Query: 3421 DPEMKNLPDTKAITQKEEIHRKKTVPEEAWPNNKESLQINIEESECHSEFENTTRSVFRS 3480
            DPEMKNLPDTKAITQKEEIHRKKTVPEEAWPNNKESLQINIEESECHSEFENTTRSVFRS
Sbjct: 3421 DPEMKNLPDTKAITQKEEIHRKKTVPEEAWPNNKESLQINIEESECHSEFENTTRSVFRS 3480

Query: 3481 AKFYIHHPVHLPSDQDICHESLGKSVFMRHSWKDFFQHHPDKHREHMCLPLPYQNMDKTK 3540
            AKFYIHHPVHLPSDQDICHESLGKSVFMRHSWKDFFQHHPDKHREHMCLPLPYQNMDKTK
Sbjct: 3481 AKFYIHHPVHLPSDQDICHESLGKSVFMRHSWKDFFQHHPDKHREHMCLPLPYQNMDKTK 3540

Query: 3541 TDYTRIKSLSINVNLGNKEVMDTTKSQVRDYPKHNGQISDPQRDQKVTPEQTTQHTVSLN 3600
            TDYTRIKSLSINVNLGNKEVMDTTKSQVRDYPKHNGQISDPQRDQKVTPEQTTQHTVSLN
Sbjct: 3541 TDYTRIKSLSINVNLGNKEVMDTTKSQVRDYPKHNGQISDPQRDQKVTPEQTTQHTVSLN 3600

Query: 3601 ELWNKYRERQRQQRQPELGDRKELSLVDRLDRLAKILQNPITHSLQVSESTHDDSRGERS 3660
            ELWNKYRERQRQQRQPELGDRKELSLVDRLDRLAKILQNPITHSLQVSESTHDDSRGERS
Sbjct: 3601 ELWNKYRERQRQQRQPELGDRKELSLVDRLDRLAKILQNPITHSLQVSESTHDDSRGERS 3660

Query: 3661 VKEWSGRQQQRNKLQKKKRFKSLEKSHKNTGELKKSKVLSHHRAGRSNQIKIEQIKFDKY 3720
            VKEWSGRQQQRNKLQKKKRFKSLEKSHKNTGELKKSKVLSHHRAGRSNQIKIEQIKFDKY
Sbjct: 3661 VKEWSGRQQQRNKLQKKKRFKSLEKSHKNTGELKKSKVLSHHRAGRSNQIKIEQIKFDKY 3720

Query: 3721 ILSKQPGFNYISNTSSDCRPSEESELLTDTTTNILSGTTSTVESDILTQTDREVALHERS 3780
            ILSKQPGFNYISNTSSDCRPSEESELLTDTTTNILSGTTSTVESDILTQTDREVALHERS
Sbjct: 3721 ILSKQPGFNYISNTSSDCRPSEESELLTDTTTNILSGTTSTVESDILTQTDREVALHERS 3780

Query: 3781 SSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKRSKHSKKVLNTGHPLVT 3840
            SSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKRSKHSKKVLNTGHPLVT
Sbjct: 3781 SSVSTIDTARLIQAFGHERVCLSPRRIKLYSSITNQQRRYLEKRSKHSKKVLNTGHPLVT 3840

Query: 3841 SEHTRRRHIQVANHVISSDSISSSASSFLSSNSTFCNKQNVHMLNKGIQAGNLEIVNGAK 3900
            SEHTRRRHIQVANHVISSDSISSSASSFLSSNSTFCNKQNVHMLNKGIQAGNLEIVNGAK
Sbjct: 3841 SEHTRRRHIQVANHVISSDSISSSASSFLSSNSTFCNKQNVHMLNKGIQAGNLEIVNGAK 3900

Query: 3901 KHTRDVGITFPTPSSSEAKLEENSDVTSWSEEKREEKMLFTGYPEDRKLKKNKKNSHEGV 3960
            KHTRDVGITFPTPSSSEAKLEENSDVTSWSEEKREEKMLFTGYPEDRKLKKNKKNSHEGV
Sbjct: 3901 KHTRDVGITFPTPSSSEAKLEENSDVTSWSEEKREEKMLFTGYPEDRKLKKNKKNSHEGV 3960

Query: 3961 SWFVPVENVESRSKKENVPNTCGPGISWFEPITKTRPWREPLREQNCQGQHLDGRGYLAG 4020
            SWFVPVENVESRSKKENVPNTCGPGISWFEPITKTRPWREPLREQNCQGQHLDGRGYLAG
Sbjct: 3961 SWFVPVENVESRSKKENVPNTCGPGISWFEPITKTRPWREPLREQNCQGQHLDGRGYLAG 4020

Query: 4021 PGREAGRDLLRPFVRATLQESLQFHRPDFISRSGERIKRLKLIVQERKLQSMLQTERDAL 4080
            PGREAGRDLLRPFVRATLQESLQFHRPDFISRSGERIKRLKLIVQERKLQSMLQTERDAL
Sbjct: 4021 PGREAGRDLLRPFVRATLQESLQFHRPDFISRSGERIKRLKLIVQERKLQSMLQTERDAL 4080

Query: 4081 FNIDRERQGHQNRMCPLPKRVFLAIQKNKPISKKEMIQRSKRIYEQLPEVQKKREEEKRK 4140
            FNIDRERQGHQNRMCPLPKRVFLAIQKNKPISKKEMIQRSKRIYEQLPEVQKKREEEKRK
Sbjct: 4081 FNIDRERQGHQNRMCPLPKRVFLAIQKNKPISKKEMIQRSKRIYEQLPEVQKKREEEKRK 4140

Query: 4141 SEYKSYRLRAQLYKKRVTNQLLGRKVPWD 4169
            SEYKSYRLRAQLYKKRVTNQLLGRKVPWD
Sbjct: 4141 SEYKSYRLRAQLYKKRVTNQLLGRKVPWD 4169


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score =  124 bits (311), Expect = 2e-27
 Identities = 400/1817 (22%), Positives = 625/1817 (34%), Gaps = 321/1817 (17%)

Query: 466  PDTVPKAPKHLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSS 525
            P + P    H  A  T+ G   + T  +   G T T +     +   L  E  +    S 
Sbjct: 1614 PSSTPTT--HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG 1671

Query: 526  PLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIF 585
              ETT    + T    +   T              PA   T +  V   S +   +P   
Sbjct: 1672 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS--TTSSGVSEESTTSHSRPGST 1729

Query: 586  YQQGLPDSH----LTEEALKVSAAPGLADQT-----TGMSTLTSTSYSHREKPGTFYQQE 636
            +    P S     +++E+    ++PG  D T     T  S+L   S +    PG+     
Sbjct: 1730 HTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL 1789

Query: 637  LPESNLTEEPLEVSAAPGPVEQKTGIP-TVSSTSHSHVEDLLFFYRQTLPDGHLTDQALK 695
            LP++      LE S    PV   TG P T  S + S           T      T Q+  
Sbjct: 1790 LPDNTTASGLLEAST---PVHSSTGSPHTTLSPAGS----------TTRQGESTTFQSWP 1836

Query: 696  VSAVSGPADQKTGTATVLSTPHSH---REKPGIFYQQEFADSHQTEETLTKVSA------ 746
             S  + PA   T +A V  +  SH      P   +        ++EE+ T  S+      
Sbjct: 1837 SSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATAT 1896

Query: 747  TPGPADQKTEIPAVQSSSY--SQREKPSILYPQDLADSHLPEEGLK-----VSAVAGPAD 799
            TP PA   T     +S++Y  S     ++ +P+    S   EE           ++ P  
Sbjct: 1897 TPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPS 1956

Query: 800  QKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSS 859
              + L   P+S +S        +     DS       + S  S  +   TGT  + + S+
Sbjct: 1957 TTSALVEEPTSYHSSPGSTATTH---FPDSSTTSGRSEESTASHSSQDATGTIVLPARST 2013

Query: 860  ASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFS 919
             S  LGE  +         S ++  +++ + +PG      G+    ++F+S    P    
Sbjct: 2014 TSVLLGESTT---------SPISSGSMETTALPG-STTTPGLSEKSTTFHSSPRSP---- 2059

Query: 920  QQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSD----L 975
                             A ++  A  T +     ++ SHS   S  +    PDS     L
Sbjct: 2060 -----------------ATTLSPASTTSSGVSEESTTSHSRPGST-HTTAFPDSTTTPGL 2101

Query: 976  PRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPG 1035
             R S    + PG TD   +P  T  SG       PS    QE   S+++  +   +  PG
Sbjct: 2102 SRHSTTSHSSPGSTDTTLLPASTTTSG-------PS----QESTTSHSSPGSTDTALSPG 2150

Query: 1036 PADQKTEIPAVQSSSYPQREKPSV---LYPQVLSDSHLPEESLKVSAFPGPADQMTDTPA 1092
                 T +   Q S+       S    L+P   + S + E S +V +  G + + T +PA
Sbjct: 2151 ST---TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSPA 2206

Query: 1093 VPSTFYSQREKPGIFYQQTLPES-HLPKEALKISVAPGLADQKT-------GTPTV---T 1141
              ++   Q E       QT P S H        + AP   ++ T        TPT     
Sbjct: 2207 SSTSPGLQGESTAF---QTHPASTHTTPSPPSTATAP--VEESTTYHRSPGSTPTTHFPA 2261

Query: 1142 STSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGI 1201
            S++ S H EK +IFH         P  A   S  +G G   T            R  PG 
Sbjct: 2262 SSTTSGHSEKSTIFHSSPDASGTTPSSAH--STTSGRGESTT-----------SRISPGS 2308

Query: 1202 FYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTE 1261
                TLPGS                   T TP  + AS +    P            PT 
Sbjct: 2309 TEITTLPGS-------------------TTTPGLSEASTTFYSSP----------RSPTT 2339

Query: 1262 EALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPA 1321
                 S+ S       G    ++TS SQ     S     S  +  L+EE+  V +    +
Sbjct: 2340 TLSPASMTS------LGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGS 2393

Query: 1322 DQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTS 1381
             + TV P  P+T     E+P  F      HS P      +       D TT   T  ST+
Sbjct: 2394 TETTVFPRTPTTSV-RGEEPTTF------HSRPASTHTTLFTE----DSTTSGLTEESTA 2442

Query: 1382 YSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQ 1441
            +             +L  + L EE+    +  G     TG    P+              
Sbjct: 2443 FPGSPASTQTGLPATLTTADLGEESTTFPSSSG----STGTTLSPA-----RSTTSGLVG 2493

Query: 1442 QVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKP----IVIYKQAFPEGHLP 1497
            +  P S L   + E +  PG    +  TP+++  S++F   P      +         + 
Sbjct: 2494 ESTP-SRLSPSSTETTTLPG----SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVS 2548

Query: 1498 EESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGS--------FYQLALLGSQIPEEAL 1549
            EES      PG    T    + T+P  S+H   S S            +   S   +E+ 
Sbjct: 2549 EESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 2608

Query: 1550 RVSSAPGPADQTTGIPTITSTSYSFGEK-------PIVNYKQAFPDGHLPEEALKVSIVS 1602
               S+PG  D  T +   ++T+ SFG++       P   +   FPD          +  S
Sbjct: 2609 TSHSSPGSTD--TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---------TTSS 2657

Query: 1603 GPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPV- 1661
            G  E  T + +   GS      P +     L       +    S    P+   T T PV 
Sbjct: 2658 GIVEASTRVHSS-TGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVE 2716

Query: 1662 HSTSY--SNRGKPVIFYQQTLSDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKP 1719
             ST+Y  S    P   +  + + S   E++        PDA  T TPS + S  S R + 
Sbjct: 2717 ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH--SSPDASGT-TPSSAHSTTSGRGES 2773

Query: 1720 IVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQ-QELPDSH 1778
                      S ++  + +++ +P  +    GLS  +++FYS    P  +     +    
Sbjct: 2774 TT--------SRISPGSTEITTLP-GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLG 2824

Query: 1779 LTEEALKVSNVPG-------PADQKT-GVSTVTSTSYSHREKPIVSYQRELPHFTEAGLK 1830
            + EE+    + PG       PA   T G+S  ++T YS    P  +     P  T   ++
Sbjct: 2825 VGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYS--SSPGSTETTVFPRSTTTSVR 2882

Query: 1831 ILRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPG-PADQKTGI 1889
                    ++ T  +  P++++     ++ + +     LTE   ++   PG PA  +TG+
Sbjct: 2883 -------GEEPTTFHSRPASTHT----TLFTEDSTTSGLTE---ESTAFPGSPASTQTGL 2928

Query: 1890 QIASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPS 1949
                +++    E  +          T              R T    V  S  SR   PS
Sbjct: 2929 PATLTTADLGEESTTFPSSSGSTGTTLSPA----------RSTTSGLVGESTPSRL-SPS 2977

Query: 1950 VISQQELPDSHLT------EEALKVSPVSIPA--EQKTGIPIGLSSSYSHSHKEKLKIST 2001
                  LP S  T            SP S  A     T    G+S   S SH +     T
Sbjct: 2978 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 3037

Query: 2002 VHIPDDQKT----EFPAATLSSYSQIE---KPKISTVIGPNDQKTPSQTAFHSSYSQTVK 2054
               PD   T    + P A+ SS    E    P  +T      Q     T FHSS      
Sbjct: 3038 TAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQ----STTFHSS------ 3087

Query: 2055 PNILFQQQLPDRDQSKGILKISAVPELT--DVNTGKPVSLSSSYFHREKSNIFSPQELPG 2112
            P       LPD   + G+++ S     +   ++T    + S+S   +E+S  F  Q  P 
Sbjct: 3088 PGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTF--QSWPS 3145

Query: 2113 SHVTEDVLKVSTIPGPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSA 2172
            S          T P P G  T  P  + +++  R           P  H +      S+ 
Sbjct: 3146 SS--------DTTPSPPG-TTAAPVEVSTTYHSR-------PSSTPTTHFSAS----STT 3185

Query: 2173 LGQADQITGLQTVPSGT 2189
            LG++++ T + + P  T
Sbjct: 3186 LGRSEESTTVHSSPGAT 3202



 Score =  120 bits (300), Expect = 4e-26
 Identities = 382/1855 (20%), Positives = 626/1855 (33%), Gaps = 304/1855 (16%)

Query: 472  APKHLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSL---EDLSQLAVSSPLE 528
            A KH     T+ G   + T S+   G T T +     SH + S+   E  +    S+ +E
Sbjct: 207  ATKHFLDSSTNSGHSEESTVSHSGPGATGTTL---FPSHSATSVFVGEPKTSPITSASME 263

Query: 529  TTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQ-----KTATPTVLSSSHSHRGKPS 583
            TT    + T          L+E++    + P   D+     +T +  V   S +   +P 
Sbjct: 264  TTALPGSTTT-------AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPG 316

Query: 584  IFYQQGLPDSH----LTEEALKVSAAPGLADQTTGMSTLTSTSY-----SHREKPGTFYQ 634
              +    PDS     +++E+    + PG  D T    T T +S      +    PG    
Sbjct: 317  PTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKT 376

Query: 635  QELPESNLTEEPLEVSAAPGPVEQKTGIPTVS---STSHSHVEDLLFFYRQTLPDGHLTD 691
              LP++  T   LE S    PV   TG P  +   S+S +H  +   F  Q+ P    T 
Sbjct: 377  TRLPDNTTTSGLLEAST---PVHSSTGSPHTTLSPSSSTTHEGEPTTF--QSWPSSKDTS 431

Query: 692  QALKVSAVSGPADQKTGTATVLSTPHSH--REKPGIFYQQEFADSHQTEETLTKVSATPG 749
             A   +  +      T  ++  STP +H       + + +E    H +       + TP 
Sbjct: 432  PAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSP---VATATTPP 488

Query: 750  PADQKTEIPAVQSSSY--SQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTV 807
            PA   T     +S++Y  S     ++ +P+    S   EE              T   T 
Sbjct: 489  PARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTA 548

Query: 808  PSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPA-DGKTGTPAVTSTSSASSSLGE 866
              +  S+   L         DS         S +SG + + K    +  + ++     G 
Sbjct: 549  ALAHTSYHSSLGSTETTHFRDS---------STISGRSEESKASHSSPDAMATTVLPAGS 599

Query: 867  KPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDF 926
             PS     + P S ++  +++ + +PG    K G+    ++FYS    P           
Sbjct: 600  TPSVLVGDSTP-SPISSGSMETTALPG-STTKPGLSEKSTTFYSSPRSP----------- 646

Query: 927  LFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDS----DLPRESLKM 982
                        + L A  T +     ++ SHS   S  +    P S     L +ES   
Sbjct: 647  ----------DTTHLPASMTSSGVSEESTTSHSRPGST-HTTAFPGSTTMPGLSQESTAS 695

Query: 983  SAIPGLTDQKTVPTPTVPSG----SFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPAD 1038
             + PG TD    P  T  S       +   +P        PD+      L+ S     + 
Sbjct: 696  HSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSST 755

Query: 1039 QKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTP-AVPSTF 1097
            +        + S  ++ + +  +    S    P      SAF  P+     +P ++P+T 
Sbjct: 756  RSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTH 815

Query: 1098 YSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHR-------- 1149
             S R       +++      P     +           G  + TS S + H         
Sbjct: 816  ISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTT 875

Query: 1150 ----EKPSIFHQQALPG----THIPEEA----------------QKVSAVTGPGNQKTWI 1185
                E+P+ +H    PG    TH P+ +                     +  P    T +
Sbjct: 876  SALVEEPTSYHSS--PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 933

Query: 1186 PRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGT---PTPTSASYSH 1242
              +L    +     G      LPGS       + S     + +   T   P  T++S   
Sbjct: 934  --LLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVS 991

Query: 1243 TE------KPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGT---PAVTSTSYSQYREK 1293
             E      +PG  +    PD+  T    + S  S     +T T   PA T+TS       
Sbjct: 992  EESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS------G 1045

Query: 1294 PSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSH 1353
            PS    Q   +SH +  + + +  PG     +      +TF+S+   PG  +  + P S 
Sbjct: 1046 PS----QESTTSHSSSGSTDTALSPGSTTALS-FGQESTTFHSN---PGSTHTTLFPDST 1097

Query: 1354 PTEEALKISVASEPVDQTTGTPTVT---STSYSQHTEKPSIFYQQSLPGSHLTEEAKNVS 1410
             +   ++   AS  V  +TG+P  T   ++S S   +  S  +Q     +H T    + +
Sbjct: 1098 TSSGIVE---ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 1154

Query: 1411 AVP---------GPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVS---- 1457
              P          PG   T      ST   H+EK   F+         P  A   +    
Sbjct: 1155 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 1214

Query: 1458 ------VAPGPVDQT-----IGTPTVTSPSSSFGEKP----IVIYKQAFPEGHLPEESLK 1502
                  ++PG  + T       TP ++  S++F   P      +   +     + EES  
Sbjct: 1215 ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTT 1274

Query: 1503 VSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTT 1562
                PG    T    + T+P  S                    EE+  V S+   + +TT
Sbjct: 1275 SRSQPGSTHSTVSPASTTTPGLS--------------------EESTTVYSSSRGSTETT 1314

Query: 1563 GIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALG 1622
              P  T+TS   GE+P   + +  P         + S  SG TE+ T  P  P  +    
Sbjct: 1315 VFPHSTTTSV-HGEEPTTFHSR--PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ--- 1368

Query: 1623 EKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSD 1682
                T     L  + L +E     ++ G     T+  P  ST+    G+         + 
Sbjct: 1369 ----TGLPATLTTADLGEESTTFPSSSGSTG--TKLSPARSTTSGLVGES--------TP 1414

Query: 1683 SHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFY-QQALPDSELTQEALKVSA 1741
            S L   + +   +PG       TPS+S       EK   FY     PD+ L+      S 
Sbjct: 1415 SRLSPSSTETTTLPG----SPTTPSLS-------EKSTTFYTSPRSPDATLSPATTTSSG 1463

Query: 1742 VPQPADQKTGL--STVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGV 1799
            V + +        ST T++F   T   ++S  QE   SH ++ + + +  PG     T  
Sbjct: 1464 VSEESSTSHSQPGSTHTTAFPDSTTTSDLS--QEPTTSHSSQGSTEATLSPG----STTA 1517

Query: 1800 STVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTG---INILPSNSYPQRE 1856
            S++   S +    P  +    LP  T     ++    P    TG     + P++S     
Sbjct: 1518 SSLGQQSTTFHSSPGDTETTLLPDDTITS-GLVEASTPTHSSTGSLHTTLTPASSTSAGL 1576

Query: 1857 HSVISYEQELPDLTEVTLKAIGVPG------------PADQKTGIQIASSSSYSNREKAS 1904
                +  Q  P  ++ T    G               P+   T    ASS++    E+++
Sbjct: 1577 QEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEEST 1636

Query: 1905 IFHQQELPDVTEEALNVFVVPGQGDRKT---EIPTVPLSYYSRREK--PSVISQQELPDS 1959
              H    P  T  AL     P +        E  T P+S  S      P   +   L + 
Sbjct: 1637 TVHSS--PGATGTAL----FPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEK 1690

Query: 1960 HLTEEALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSS 2019
              T  +   SP +  +   T    G+S   + SH       T   P    T  P  +  S
Sbjct: 1691 STTFYSSPRSPDTTLSPAST-TSSGVSEESTTSHSRPGSTHTTAFPG--STTMPGVSQES 1747

Query: 2020 YSQIEKP-KISTVIGPNDQKT----PSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILK 2074
             +    P    T + P         P  T FHSS      P       LPD   + G+L+
Sbjct: 1748 TASHSSPGSTDTTLSPGSTTASSLGPESTTFHSS------PGSTETTLLPDNTTASGLLE 1801

Query: 2075 ISAVPELTDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTV 2134
             S     +  +    +S + S   + +S  F  Q  P S          T+P P      
Sbjct: 1802 ASTPVHSSTGSPHTTLSPAGSTTRQGESTTF--QSWPSSK--------DTMPAP------ 1845

Query: 2135 LPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGT 2189
             PT   S+F              P  H +      S+ LG++++ T + + P  T
Sbjct: 1846 -PTT-TSAFVELSTTSHGSPSSTPTTHFSAS----STTLGRSEESTTVHSSPVAT 1894



 Score =  113 bits (282), Expect = 5e-24
 Identities = 383/1866 (20%), Positives = 629/1866 (33%), Gaps = 284/1866 (15%)

Query: 478  AGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPL--ETTTGQHT 535
            A  T+ G + + T S L    T T      GS  + SL + S    +SP   + T    T
Sbjct: 2484 ARSTTSGLVGESTPSRLSPSSTETTTLP--GSPTTPSLSEKSTTFYTSPRSPDATLSPAT 2541

Query: 536  DTLN--QKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDS 593
             T +   +  + +H    +   TA P+     T TP +   S +    P       LP S
Sbjct: 2542 TTSSGVSEESSTSHSQPGSTHTTAFPD----STTTPGLSRHSTTSHSSPGSTDTTLLPAS 2597

Query: 594  HLT----EEALKVSAAPGLADQTTGMSTLTSTSYSHRE-----KPGTFYQQELPESNLTE 644
              T    +E+    ++PG  D      + T+ S+          PG+ +    P+S  + 
Sbjct: 2598 TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS 2657

Query: 645  EPLEVSAAPGPVEQKTGIPTV-----SSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAV 699
              +E S     V   TG P       SSTS     +   F  QT P    T  +   +A 
Sbjct: 2658 GIVEASTR---VHSSTGSPRTTLSPASSTSPGLQGESTTF--QTHPASTHTTPSPPSTAT 2712

Query: 700  S----------GPADQKTGTATVLSTPHSHREKPGIFYQQEFAD------SHQT-----E 738
            +           P    T      ST   H EK  IF+    A       +H T     E
Sbjct: 2713 APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE 2772

Query: 739  ETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPA 798
             T +++S  PG  +  T   +  +   S+        P+    +  P     +    G  
Sbjct: 2773 STTSRIS--PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSL----GVG 2826

Query: 799  DQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTS 858
            ++ T   + P S +S           +     L EE+  V + S  +   T  P  T+TS
Sbjct: 2827 EESTTSRSQPGSTHS------TVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTS 2880

Query: 859  SASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIF 918
                  GE+P+ F+ +  P S  T    + S   G  ++ T  P +P+S  +     +  
Sbjct: 2881 VR----GEEPTTFHSR--PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 2934

Query: 919  SQQTLPDFLFPEEALKVSAVSVLAAQKT----GTPTVSSNSHSHSEKSSVFYQQELPDSD 974
            +        FP  +         A   T    G  T S  S S +E +++      P   
Sbjct: 2935 ADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS-- 2992

Query: 975  LPRESLKMSAIPGLTDQKTVPTPTVPSG----SFSHREKPSIFYQQEWPDSYATEKALKV 1030
            L  +S      P   D    P  T  SG    S +   +P   +   +PDS  T    + 
Sbjct: 2993 LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQE 3052

Query: 1031 STGPGPADQKTEIP----AVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQ 1086
             T    +   TE      +  +SS  Q+       P     + LP++++           
Sbjct: 3053 PTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 3112

Query: 1087 MTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYS 1146
             + T ++ +T            +++      P  +      PG     T  P   ST+Y 
Sbjct: 3113 HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGT----TAAPVEVSTTY- 3167

Query: 1147 QHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQT 1206
                +PS     + P TH        S   G   + T       T +S     G     T
Sbjct: 3168 --HSRPS-----STPTTHFSAS----STTLGRSEEST-------TVHSSPGATGTALFPT 3209

Query: 1207 LPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVL-PDNHPTEEALK 1265
               + +       SP+   + + T  P  T+ +   +EK   FY     PD   +  +  
Sbjct: 3210 RSATSVLVGEPTTSPISSGSTETTALPGSTTTA-GLSEKSTTFYSSPRSPDTTLSPASTT 3268

Query: 1266 ISVASEPVDQTTGTPAVT-STSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQK 1324
             S  SE    +   P  T +T++      P +   Q   +SH +  + + +  PG     
Sbjct: 3269 SSGVSEESTTSHSRPGSTHTTAFPGSTTMPGV--SQESTASHSSPGSTDTTLSPGSTTAS 3326

Query: 1325 TVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQ 1384
            ++ P   +TF+S    PG     +LP +      L+   AS PV  +TG+P  T +    
Sbjct: 3327 SLGPE-STTFHSG---PGSTETTLLPDNTTASGLLE---ASTPVHSSTGSPHTTLSPAGS 3379

Query: 1385 HTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFY-SHTEKPGSFYQQV 1443
             T +      QS P S  T         P P    +    L +T + S +  P + +   
Sbjct: 3380 TTRQGESTTFQSWPNSKDT--------TPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS 3431

Query: 1444 LPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKV 1503
                   EE+  V  +P      + T T  SP+ S                 L EES   
Sbjct: 3432 STTLGRSEESTTVHSSP------VATATTPSPARS-------------TTSGLVEESTTY 3472

Query: 1504 SVAPG-------PVGQTT---GAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSS 1553
              +PG       P   TT   G  + TS S + H   S      AL+     EE     S
Sbjct: 3473 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALV-----EEPTSYHS 3527

Query: 1554 APGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPA 1613
            +PG +  TT  P  +ST+    E+   ++      G +   A   + V       + I +
Sbjct: 3528 SPG-STATTHFPD-SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 3585

Query: 1614 GPLGSSA---------LGEKPITFYRQ-----------ALLDSPLNKEVVKVSAAPG--- 1650
            G + ++A         L EK  TF+             +   S +++E     + PG   
Sbjct: 3586 GSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTH 3645

Query: 1651 ----PADQKTETLPVHS-TSYSNRGK----------PVIFYQQTLSDSHLPEEALKVPPV 1695
                P    T  L  HS TS+S+ G                 Q  + SH    +      
Sbjct: 3646 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALS 3705

Query: 1696 PGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTV 1755
            PG     T   S      ++   P   +    PDS  +   ++ S         TG    
Sbjct: 3706 PG----STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAST---RVHSSTGSPRT 3758

Query: 1756 TSSFYSHT----EKPNISYQQELPDSHLTEEALKVSNVP---------GPADQKTGVSTV 1802
            T S  S T    +  + ++Q     +H T      +  P          P    T     
Sbjct: 3759 TLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPA 3818

Query: 1803 TSTSYSHREKPIVSYQR--------ELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQ 1854
            +ST+  H EK  + +             H T +G         +   T I  LP ++   
Sbjct: 3819 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP 3878

Query: 1855 --REHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELP 1912
               E S   Y       T ++  ++   G  ++ T  +    S++S    AS       P
Sbjct: 3879 GLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS----TTTP 3934

Query: 1913 DVTEEALNVFVVPGQGDRKTEIPTVPLSYYS--RREKP-----------SVISQQELPDS 1959
             ++EE+  V+         TE    P S  +  RRE+P           + +  ++   S
Sbjct: 3935 GLSEESTTVY---SSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTS 3991

Query: 1960 HLTEEALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSS 2019
             LTEE+        PA  +TG+P  L+++                  ++ T FP+++ S+
Sbjct: 3992 GLTEESTAFP--GSPASTQTGLPATLTTADL---------------GEESTTFPSSSGST 4034

Query: 2020 YSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTV------------KPNILFQQQLPDRD 2067
             +++  P  ST  G   + TPS+ +  S+ + T+                    + PD  
Sbjct: 4035 GTKL-SPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 4093

Query: 2068 QSKGILKISAVPELTDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPG 2127
             S      S V E +  +  +P S  ++ F    +     QE   SH ++   + +  PG
Sbjct: 4094 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPG 4153

Query: 2128 PAGQKTVLPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPS 2187
                 T   +    S +    P       LPD  +T   ++ S+    +         P+
Sbjct: 4154 ----STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPA 4209

Query: 2188 GTYSHG 2193
             + S G
Sbjct: 4210 SSTSTG 4215



 Score =  112 bits (281), Expect = 6e-24
 Identities = 388/1805 (21%), Positives = 627/1805 (34%), Gaps = 314/1805 (17%)

Query: 475  HLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQH 534
            H    DT+ G   + T S+     +TT   S   S  S  +E+ +    SSP  T T   
Sbjct: 3483 HFPESDTTSGRGEESTTSHS----STTHTISSAPSTTSALVEEPTSYH-SSPGSTATTHF 3537

Query: 535  TDTLNQKTLAD----THLTEETLKVTAIPEPADQ-----KTATPTVLSSSHSHRGKPSIF 585
             D+      ++    +H +++      +P  +       ++ T  + S S      P   
Sbjct: 3538 PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST 3597

Query: 586  YQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEE 645
               GL +   T  +   S A  L+  +T  S ++  S +   +PG+ +    P+S  T  
Sbjct: 3598 TTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTT-- 3655

Query: 646  PLEVSAAPGPVEQKTGIPTVSSTSHSH--VEDLLFFYRQTLPDGHLTDQALKVSAVSGPA 703
                           G+   S+TSHS     D       T   G   +     S+ SG  
Sbjct: 3656 --------------PGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSS-SGST 3700

Query: 704  DQ--KTGTATVLS---TPHSHREKPGIFYQQEFADSHQTE---ETLTKVSATPGPADQKT 755
            D     G+ T LS      +    PG  +   F DS  +    E  T+V ++ G + + T
Sbjct: 3701 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTT 3759

Query: 756  EIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHR 815
              PA  +S   Q E  S  +    A +H        S    P ++ T     P S  +  
Sbjct: 3760 LSPASSTSPGLQGE--STAFQTHPASTHTTPS--PPSTATAPVEESTTYHRSPGSTPTTH 3815

Query: 816  EKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEK--PSAFYQ 873
                 F   +    H   E   +   S  A G T + A ++TS    S   +  P +   
Sbjct: 3816 -----FPASSTTSGH--SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 3868

Query: 874  QTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEAL 933
             TLP S  T         PG  +  T   S+P S                     P   L
Sbjct: 3869 TTLPGSTTT---------PGLSEASTTFYSSPRS---------------------PTTTL 3898

Query: 934  KVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKM-SAIPGLTDQK 992
              ++++ L   +  T + S    +HS  S            L  ES  + S+ PG T+  
Sbjct: 3899 SPASMTSLGVGEESTTSRSQPGSTHSTVSPA----STTTPGLSEESTTVYSSSPGSTETT 3954

Query: 993  TVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYP 1052
              P  T  S     RE+P+ F+ +  P S  T    + ST  G  ++ T  P   +S+  
Sbjct: 3955 VFPRSTTTS---VRREEPTTFHSR--PASTHTTLFTEDSTTSGLTEESTAFPGSPAST-- 4007

Query: 1053 QREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTL 1112
                     P  L+ + L EES   + FP  +   T T   P    ++    G+  + T 
Sbjct: 4008 -----QTGLPATLTTADLGEES---TTFPSSSGS-TGTKLSP----ARSTTSGLVGEST- 4053

Query: 1113 PESHLPKEALKISVAPGLADQKTGTPTV---TSTSYSQHREKPSIFHQQALPGTHIPEEA 1169
              S L   + + +  PG       TP++   ++T Y+  R   +         + + EE+
Sbjct: 4054 -PSRLSPSSTETTTLPG----SPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 4108

Query: 1170 QKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQK 1229
               ++ + PG+  T      + F       G+  + T   S        +SP        
Sbjct: 4109 S--TSHSQPGSTHT------TAFPDSTTTSGLSQEPTTSHSSQGSTEATLSP-------- 4152

Query: 1230 TGTPTPTSASYSHT---EKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTS 1286
             G+ T +S     T     PG     +LPD+  T   ++   AS P   +TG+   T T 
Sbjct: 4153 -GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVE---ASTPTHSSTGSLHTTLTP 4208

Query: 1287 YSQ----YREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPG 1342
             S      +E+ + F  QS PSS  T         P P    T +P+  ST Y H+    
Sbjct: 4209 ASSTSTGLQEESTTF--QSWPSSSDT--------TPSP-PSTTAVPVEVSTTY-HSR--- 4253

Query: 1343 VFYQQVLPHSHPTEEALKISVA---SEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPG 1399
                   P S PT      S     SE       +P  T T+        S+   +    
Sbjct: 4254 -------PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT- 4305

Query: 1400 SHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQV-LPHSHLPEEALEVSV 1458
            S ++  +   +A+PG      G+    +TFYS    P +         S + EE+     
Sbjct: 4306 SPISSGSTETTALPG-STTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 4364

Query: 1459 APGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPT 1518
             PG +  T    + T P  S          Q     H    S   +++PG    +T A +
Sbjct: 4365 RPGSMHTTAFPSSTTMPGVS----------QESTASHSSPGSTDTTLSPG----STTASS 4410

Query: 1519 ITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEKP 1578
            +   S + H +   +  +  LL        L  +S   P   +TG P  T +        
Sbjct: 4411 LGPESTTFHSSPGST--ETTLLPDNTTASGLLEAST--PVHSSTGSPHTTLS-------- 4458

Query: 1579 IVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPL 1638
                    P G    +    +  S P  K T  PA P  +SA  E   T +      SP 
Sbjct: 4459 --------PAGSTTRQGESTTFQSWPNSKDT-TPAPPTTTSAFVELSTTSH-----GSPS 4504

Query: 1639 NKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPG- 1697
            +      SA+     +  E+  VHS+  +    P      T   S L EE+      PG 
Sbjct: 4505 STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT---SGLVEESTTYHSSPGS 4561

Query: 1698 ------PDAQKT------ETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQP 1745
                  P++  T       T S SS+ ++    P          S L +E     + P  
Sbjct: 4562 TQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPST-------TSALVEEPTSYHSSPG- 4613

Query: 1746 ADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTST 1805
                   ST T+ F   +     S  +E   SH +++A     +  PA   T V    ST
Sbjct: 4614 -------STATTHFPDSSTTSGRS--EESTASHSSQDA--TGTIVLPARSTTSVLLGEST 4662

Query: 1806 SYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSN---SYPQREHSVISY 1862
            +      PI S   E    T A       PG +++ T  +  PS+   ++     + +  
Sbjct: 4663 T-----SPISSGSME----TTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGR 4713

Query: 1863 EQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSY-SNREKASIFHQQELPDV------- 1914
             +E   +    +     P PA   T   +  S++Y S+       H  E           
Sbjct: 4714 SEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEES 4773

Query: 1915 -TEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSI 1973
             T  +     +       + +   P SY+S    P  I+    P+S  T    + S  S 
Sbjct: 4774 RTSHSSTTHTISSPPSTTSALVEEPTSYHS---SPGSIATTHFPESSTTSGRSEESTASH 4830

Query: 1974 PAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIG 2033
             +    GI   L + ++ S +     +    P   +T     TL+S +        + I 
Sbjct: 4831 SSPDTNGI-TPLPAHFTTSGRIAESTTFYISPGSMET-----TLASTATTPGLSAKSTIL 4884

Query: 2034 PNDQKTPSQT---AFHSSYSQTVKPNILFQQ-------QLPDRDQSKGILKISAV----P 2079
             +  ++P QT   A  +S S + +P  L+ Q         P    + G+ + S      P
Sbjct: 4885 YSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKP 4944

Query: 2080 ELTDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTVLPTAL 2139
              T+  T  P S+++S F +E     +P   PGS ++      +T+PG + + T   ++ 
Sbjct: 4945 GSTE-TTLSPGSITTSSFAQE---FTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSP 5000

Query: 2140 PS----SFSHREKPDIFYQKD-------------LPDRHLTEDALKISSALGQADQITGL 2182
             S    +FSH     I  Q+              LP    T D  + S+A   +   TG 
Sbjct: 5001 GSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGT 5060

Query: 2183 QTVPS 2187
              +P+
Sbjct: 5061 TPLPA 5065



 Score =  106 bits (264), Expect = 6e-22
 Identities = 395/1862 (21%), Positives = 652/1862 (35%), Gaps = 286/1862 (15%)

Query: 475  HLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQH 534
            H    DT+ G   + T S+     +TT   S   S  S  +E+ +    SSP  T T   
Sbjct: 843  HFPESDTTSGRGEESTTSHS----STTHTISSAPSTTSALVEEPTSYH-SSPGSTATTHF 897

Query: 535  TDTLNQKTLAD----THLTEETLKVTAIPEPADQ-----KTATPTVLSSSHSHRGKPSIF 585
             D+      ++    +H +++      +P  +       ++ T  + S S      P   
Sbjct: 898  PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST 957

Query: 586  YQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEE 645
               GL +   T  +   S A  L+  +T  S ++  S + R +PG+ +    P+S  T  
Sbjct: 958  TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTT-- 1015

Query: 646  PLEVSAAPGPVEQKTGIPTVSSTSHSH--VEDLLFFYRQTLPDGHLTDQALKVSAVSGPA 703
                           G+   S+TSHS     D       T   G   +     S+ SG  
Sbjct: 1016 --------------PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS-SGST 1060

Query: 704  DQ--KTGTATVLS------TPHSHREKPGIFYQQEFADSHQTE---ETLTKVSATPGPAD 752
            D     G+ T LS      T HS+   PG  +   F DS  +    E  T+V ++ G + 
Sbjct: 1061 DTALSPGSTTALSFGQESTTFHSN---PGSTHTTLFPDSTTSSGIVEASTRVHSSTG-SP 1116

Query: 753  QKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKT-------GLP 805
            + T  PA  +S   Q E  S  +    A +H        S    P ++ T         P
Sbjct: 1117 RTTLSPASSTSPGLQGE--STAFQTHPASTHTTPS--PPSTATAPVEESTTYHRSPGSTP 1172

Query: 806  T----VPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTST---- 857
            T      S+   H EK  +F+         P  A   ++  G +     +P  T      
Sbjct: 1173 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 1232

Query: 858  -SSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPI 916
             S+ +  L E  + FY    P S  T  +       G G++ T   S P S +S     +
Sbjct: 1233 GSTTTPGLSEASTTFYSS--PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS----TV 1286

Query: 917  IFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLP 976
              +  T P     EE+  V + S  + + T  P  S+ +  H E+ + F+ +  P S   
Sbjct: 1287 SPASTTTPG--LSEESTTVYSSSRGSTETTVFPH-STTTSVHGEEPTTFHSR--PASTHT 1341

Query: 977  RESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGP 1036
                + S   GLT++ T   P  P+   +    P+     +  +   T  +   STG   
Sbjct: 1342 TLFTEDSTTSGLTEESTA-FPGSPAS--TQTGLPATLTTADLGEESTTFPSSSGSTGTKL 1398

Query: 1037 ADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPS- 1095
            +  ++    +   S P R  PS               S + +  PG       +P  PS 
Sbjct: 1399 SPARSTTSGLVGESTPSRLSPS---------------STETTTLPG-------SPTTPSL 1436

Query: 1096 -----TFY-SQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHR 1149
                 TFY S R         T   S + +E+      PG +   T  P  T+TS     
Sbjct: 1437 SEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG-STHTTAFPDSTTTSDLSQE 1495

Query: 1150 EKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPG 1209
               S   Q +   T  P      +  +  G Q T       TF+S    PG      LP 
Sbjct: 1496 PTTSHSSQGSTEATLSPGS----TTASSLGQQST-------TFHS---SPGDTETTLLPD 1541

Query: 1210 SHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTE-KPGIFYQQVLPDNHPTEEALKISV 1268
              I     + S           TPT +S    HT   P       L +   T ++   S 
Sbjct: 1542 DTITSGLVEAS-----------TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS 1590

Query: 1269 ASEPVDQ-TTGTPAVTSTSY-SQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTV 1326
             + P    TT  P   ST+Y S+    P+  +  S  +   +EE+  V + PG A    +
Sbjct: 1591 DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPG-ATGTAL 1649

Query: 1327 IPILPSTFY---SHTEKP---GVFYQQVLPHSHPT----EEALKISVASEPVDQTTGTPT 1376
             P   +T       T  P   G      LP S  T    E++     +    D T    +
Sbjct: 1650 FPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 1709

Query: 1377 VTSTSYSQHT----EKPSIFYQQSLPGS----HLTEEAKNVSAVPGPGDR--KTGIPTLP 1426
             TS+  S+ +     +P   +  + PGS     +++E+    + PG  D     G  T  
Sbjct: 1710 TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 1769

Query: 1427 S------TFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTP-TVTSPSSSF 1479
            S      TF+S    PGS    +LP +      LE S    PV  + G+P T  SP+ S 
Sbjct: 1770 SLGPESTTFHS---SPGSTETTLLPDNTTASGLLEAST---PVHSSTGSPHTTLSPAGST 1823

Query: 1480 GEKPIVIYKQAFPEGH--LPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQL 1537
              +      Q++P     +P      S        + G+P+ T    + H + S +    
Sbjct: 1824 TRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTP---TTHFSASSTTLGR 1880

Query: 1538 ALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALK 1597
            +   + +    +  ++ P PA  TT      ST+Y     P       FP+        +
Sbjct: 1881 SEESTTVHSSPVATATTPSPARSTTSGLVEESTAYH--SSPGSTQTMHFPESSTASGRSE 1938

Query: 1598 VSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTE 1657
             S  S  +   T I + P  +SAL E+P +++      SP +        +   + +  E
Sbjct: 1939 ESRTSHSSTTHT-ISSPPSTTSALVEEPTSYH-----SSPGSTATTHFPDSSTTSGRSEE 1992

Query: 1658 TLPVHSTSYSNRGKPVIFYQQTLS-------DSHLPEEALKVPPVPGPDAQKTETPSVSS 1710
            +   HS S    G  V+  + T S        S +   +++   +PG     T TP +S 
Sbjct: 1993 STASHS-SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG----STTTPGLSE 2047

Query: 1711 SLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISY 1770
               ++   P      A   S  +  +  VS     +  + G ST T++F   T  P +S 
Sbjct: 2048 KSTTFHSSP---RSPATTLSPASTTSSGVSEESTTSHSRPG-STHTTAFPDSTTTPGLSR 2103

Query: 1771 QQE-------------LPDSHLT----EEALKVSNVPGPADQKTGVSTVTSTSY-----S 1808
                            LP S  T    +E+    + PG  D      + T+ S+     +
Sbjct: 2104 HSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTT 2163

Query: 1809 HREKPIVSYQRELPHFTEAGLKILRVPGPADQKTG---INILPSNSYPQREHSVISYEQE 1865
                P  ++    P  T +   I+         TG     + P++S         +  Q 
Sbjct: 2164 FHSSPGSTHTTLFPDSTTSS-GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQT 2222

Query: 1866 LPDLTEVTLKAIGVP------------GPADQKTGIQIASSSSYSNREKASIFHQQELPD 1913
             P  T  T                    P    T    ASS++  + EK++IFH      
Sbjct: 2223 HPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 2282

Query: 1914 VTEEALNVFVVPGQGDR--------KTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEA 1965
             T  +       G+G+          TEI T+P S  +     +  +    P S  T   
Sbjct: 2283 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTT--- 2339

Query: 1966 LKVSPVSIPAEQKTGIPIGLSSSYS-------HSHKEKLKISTVHIPDDQKTEFPAATLS 2018
              +SP S+     T + +G  S+ S       HS       +T  + ++  T + ++  S
Sbjct: 2340 -TLSPASM-----TSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGS 2393

Query: 2019 SYSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAV 2078
            + + +     +T +     +    T FHS  + T     LF +       ++        
Sbjct: 2394 TETTVFPRTPTTSV-----RGEEPTTFHSRPAST--HTTLFTEDSTTSGLTEESTAFPGS 2446

Query: 2079 PELTDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPG--------PAG 2130
            P  T   TG P +L+++    E +   S     G+ ++      S + G        P+ 
Sbjct: 2447 PAST--QTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSS 2504

Query: 2131 QKTVLPTALPSSFSHREKPDIFYQKD-LPDRHLTEDALKISSALGQADQITGLQTVPSGT 2189
             +T      P++ S  EK   FY     PD  L+      +++ G +++ +   + P  T
Sbjct: 2505 TETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP---ATTTSSGVSEESSTSHSQPGST 2561

Query: 2190 YS 2191
            ++
Sbjct: 2562 HT 2563


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score =  112 bits (280), Expect = 8e-24
 Identities = 291/1470 (19%), Positives = 509/1470 (34%), Gaps = 219/1470 (14%)

Query: 472  APKHLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSL---EDLSQLAVSSPLE 528
            A KH     T+ G   + T S+   G T T +     SH + S+   E  +    S+ +E
Sbjct: 128  ATKHFLDSSTNSGHSEESTVSHSGPGATGTTL---FPSHSATSVFVGEPKTSPITSASME 184

Query: 529  TTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQ-----KTATPTVLSSSHSHRGKPS 583
            TT    + T          L+E++    + P   D+     +T +  V   S +   +P 
Sbjct: 185  TTALPGSTTT-------AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPG 237

Query: 584  IFYQQGLPDSH----LTEEALKVSAAPGLADQTTGMSTLTSTSY-----SHREKPGTFYQ 634
              +    PDS     +++E+    + PG  D T    T T +S      +    PG    
Sbjct: 238  PTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKT 297

Query: 635  QELPESNLTEEPLEVSAAPGPVEQKTGIP-----TVSSTSHSHVEDLLFFYRQTLPDGHL 689
              LP++  T   LE S    PV   TG P       SST+H   E   F   Q+ P    
Sbjct: 298  TRLPDNTTTSGLLEAST---PVHSSTGSPHTTLSPASSTTHEG-EPTTF---QSWPSSKD 350

Query: 690  TDQALKVSAVSGPADQKTGTATVLSTPHSH--REKPGIFYQQEFADSHQTEETLTKVSAT 747
            T  A   +  +      T  ++  STP +H       + + +E    H +       + T
Sbjct: 351  TSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSP---VATATT 407

Query: 748  PGPADQKTEIPAVQSSSY--SQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLP 805
            P PA   T     +S++Y  S     ++ +P+    S   EE              T   
Sbjct: 408  PPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPST 467

Query: 806  TVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPA-DGKTGTPAVTSTSSASSSL 864
            T   +  S+   L         DS         S +SG + + K    +  + ++     
Sbjct: 468  TAALAHTSYHSSLGSTETTHFRDS---------STISGRSEESKASHSSPDAMATTVLPA 518

Query: 865  GEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLP 924
            G  PS     + P S ++  +++ + +PG    K G+    ++FYS    P         
Sbjct: 519  GSTPSVLVGDSTP-SPISSGSMETTALPG-STTKPGLSEKSTTFYSSPRSP--------- 567

Query: 925  DFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDS----DLPRESL 980
                          + L A  T +     ++ SHS   S  +    P S     L +ES 
Sbjct: 568  ------------DTTHLPASMTSSGVSEESTTSHSRPGST-HTTAFPGSTTMPGLSQEST 614

Query: 981  KMSAIPGLTDQKTVPTPTVPSG----SFSHREKPSIFYQQEWPDSYATEKALKVSTGPGP 1036
               + PG TD    P  T  S       +   +P        PD+      L+ S     
Sbjct: 615  ASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHS 674

Query: 1037 ADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTP-AVPS 1095
            + +        + S  ++ + +  +    S+   P      SAF  P+     +P ++P+
Sbjct: 675  STRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPT 734

Query: 1096 TFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHR------ 1149
            T  S R       +++      P     +           G  + TS S + H       
Sbjct: 735  THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPS 794

Query: 1150 ------EKPSIFHQQALPG----THIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKP 1199
                  E+P+ +H    PG    TH P+     S  +G   +           +S ++  
Sbjct: 795  TTSALVEEPTSYHSS--PGSTATTHFPDS----STTSGRSEESI-------ASHSSQDAT 841

Query: 1200 GIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHP 1259
            G         + +       SP+   + + T  P  T+        PG+  +     + P
Sbjct: 842  GTIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTT-------PGLSERSTTFHSSP 894

Query: 1260 TEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPG 1319
               A  +S AS     ++G    ++TS+S+     +  +  S  +  L+  +    + PG
Sbjct: 895  RSPATTLSPAS---TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 951

Query: 1320 PADQKTVIPILPSTFY--SHTEKP---GVFYQQVLPHSHPT----EEALKISVASEPVDQ 1370
              D  T++P   +T      T  P   G      LP S  T    E++     +    D 
Sbjct: 952  STD-TTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 1010

Query: 1371 TTGTPTVTSTSYSQHT----EKPSIFYQQSLPGS----HLTEEAKNVSAVPGPGD----- 1417
            T    + TS+  S+ +     +P   +  + PGS     +++E+    + PG  D     
Sbjct: 1011 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP 1070

Query: 1418 RKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTP-TVTSPS 1476
            R T   +L     +    PGS    +LP +      LE S    PV  + G+P T  SP+
Sbjct: 1071 RSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEAST---PVHSSTGSPRTTLSPA 1127

Query: 1477 SSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSY-------SQHRA 1529
             S   +      Q++P              P P   T+    +++ S+       + H +
Sbjct: 1128 GSTTRQGESTTFQSWPSSK--------DTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFS 1179

Query: 1530 KSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDG 1589
             S + +  +   + +    +  ++ P PA  TT      ST+Y     P       FP+ 
Sbjct: 1180 ASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYH--SSPGSTQTMHFPES 1237

Query: 1590 HLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAP 1649
                   + S  S  +   T I + P  +SAL E+P +++      S       + S   
Sbjct: 1238 STASGRSEESRTSHSSTTHT-ISSPPSTTSALVEEPTSYHSSP--GSIATTHFPESSTTS 1294

Query: 1650 GPADQKTET-----------LPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPGP 1698
            G +++ T +           LP H T+     +   FY   +S   +          PG 
Sbjct: 1295 GRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFY---ISPGSMETTLASTATTPGL 1351

Query: 1699 DAQKTETPSVS---------------------SSLYSYREKP-IVFYQQALPDSELTQEA 1736
             A+ T   S S                     +SLYS  E      +  +   S L+QE+
Sbjct: 1352 SAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQES 1411

Query: 1737 LKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQK 1796
                + P   +      ++T+S ++       +     P S L+  +   + VPG +++ 
Sbjct: 1412 TTFHSKPGSTETTLSPGSITTSSFAQ----EFTTPHSQPGSALSTVSPASTTVPGLSEES 1467

Query: 1797 T----GVSTVTSTSYSHREKPIVSYQRELP 1822
            T       +  +T++SH     +  Q+  P
Sbjct: 1468 TTFYSSPGSTETTAFSHSNTMSIHSQQSTP 1497



 Score =  100 bits (250), Expect = 2e-20
 Identities = 325/1475 (22%), Positives = 524/1475 (35%), Gaps = 307/1475 (20%)

Query: 418  GKVESDVITLDGLNENAVVCSERVAELQRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLK 477
            G+ ++  IT   +   A+  S   A L  K T    ++SS       SPD          
Sbjct: 171  GEPKTSPITSASMETTALPGSTTTAGLSEKSTT---FYSSP-----RSPDRTLSP----- 217

Query: 478  AGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDT 537
            A  TS G   K T S+ + G T T    D  +   +S E  +  ++    +TT    T T
Sbjct: 218  ARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTT 277

Query: 538  LNQKTLADT--HLTEETLKVTAIPE------------PADQKTATP-TVLS--SSHSHRG 580
             +      T  H +    K T +P+            P    T +P T LS  SS +H G
Sbjct: 278  PSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEG 337

Query: 581  KPSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPES 640
            +P+ F  Q  P S  T  A   + +  +   TT  S+ +ST       P T +       
Sbjct: 338  EPTTF--QSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSST-------PTTHFSASSTTL 388

Query: 641  NLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVS 700
              +EE   V ++P  V   T  P   S +  HVE+   ++R   P    T    + S  S
Sbjct: 389  GHSEESTPVHSSP--VATATTPPPARSATSGHVEESTAYHRS--PGSTQTMHFPESSTTS 444

Query: 701  GPADQK-----TGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKT 755
            G +++      + T T  STP +        Y         TE T  + S+T     +++
Sbjct: 445  GHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGS---TETTHFRDSSTISGRSEES 501

Query: 756  EIP-----AVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSS 810
            +       A+ ++       PS+L   D   S +    ++ +A+ G +  K GL    ++
Sbjct: 502  KASHSSPDAMATTVLPAGSTPSVLVG-DSTPSPISSGSMETTALPG-STTKPGLSEKSTT 559

Query: 811  AYSH-REKLLVFYQQALLDSHLPEEALKVSAVSGPAD-----GKTGTPAVTSTSSAS--- 861
             YS  R         ++  S + EE+    +  G        G T  P ++  S+AS   
Sbjct: 560  FYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 619

Query: 862  ---------------SSLGEKPSAFYQQT-------LPNSHLTEEALKVSIVPGPGDQKT 899
                           SSLG + + F+ +        LP++      L+ S+      +  
Sbjct: 620  PGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSP 679

Query: 900  GIPSAPSSFYSHREKPIIF-----SQQTLPD-------FLFPEEALKVSAVSV----LAA 943
                +P+   + + +   F     S  T P        F+ P      S  S+    ++A
Sbjct: 680  HTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA 739

Query: 944  QKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGS 1003
            + T +  V  ++  HS   S       P+SD      + S     +   T+ +   PS +
Sbjct: 740  RSTTSGLVEESTTYHSSPGST-QTMHFPESDTTSGRGEESTTSHSSTTHTISS--APSTT 796

Query: 1004 FSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSS----YPQREKPSV 1059
             +  E+P+ ++    P S AT      ST  G +++     + Q ++     P R   SV
Sbjct: 797  SALVEEPTSYHSS--PGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARSTNSV 854

Query: 1060 LYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVP---STFYSQREKPGIFYQQ-TLPES 1115
            L  +  + S +   S++ +A PG     T TP +    +TF+S    P       +   S
Sbjct: 855  LLGESTT-SPISSGSMETTALPGS----TTTPGLSERSTTFHSSPRSPATTLSPASTTSS 909

Query: 1116 HLPKEALKISVAPGLADQKTGTPTVTSTSYSQH----REKPSIFHQQALPG--------- 1162
             + +E+      PG         + T+   S+H       P       LP          
Sbjct: 910  GVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGE 969

Query: 1163 -THIPEEAQKVSAVTGPGNQKT-WIPRVLSTFYSQ------------------------- 1195
             T  P  +        PG+  T  +    +TFYS                          
Sbjct: 970  PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTS 1029

Query: 1196 REKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGT---PTPTSASYSHTEK------P 1246
              +PG  +    PGS       + S     +   T T   P  T+AS    E       P
Sbjct: 1030 HSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGP 1089

Query: 1247 GIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVT-STSYSQYREKPSIFYQQSLPSS 1305
            G     +LPDN      L+   AS PV  +TG+P  T S + S  R+  S  +Q S PSS
Sbjct: 1090 GSTETTLLPDNTTASGLLE---ASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQ-SWPSS 1145

Query: 1306 HLTEEAK----------------NVSAVP-----------GPADQKTVI---PILPSTFY 1335
              T  A                 + S++P           G +++ T +   P+ P+T  
Sbjct: 1146 KDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEESTTVHSSPVAPATTP 1205

Query: 1336 S--HTEKPGVFYQQVLPHSHP----TEEALKISVASEPVDQ-------TTGTPTVTSTSY 1382
            S   +   G+  +    HS P    T    + S AS   ++       TT T +   ++ 
Sbjct: 1206 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 1265

Query: 1383 SQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKT---------GIPTLPSTFYSHT 1433
            S   E+P+ ++  S PGS  T      S   G  +  T         GI  LP+ F +  
Sbjct: 1266 SALVEEPTSYH--SSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSG 1323

Query: 1434 E---------KPGSFYQQVLPHSHLP----EEALEVSVAPGPVDQTIGTPTVTSPSSSFG 1480
                       PGS    +   +  P    +  +  S +  P DQT+   ++TS  SS  
Sbjct: 1324 RIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSP-DQTLSPASMTS--SSIS 1380

Query: 1481 EKPIVIYKQA-------FPEGH----LPEESLKVSVAPGPVGQTTGAPTITSPSYSQ--- 1526
             +P  +Y QA       FP       L +ES      PG    T    +IT+ S++Q   
Sbjct: 1381 GEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFT 1440

Query: 1527 --HRAKSGSFYQLALLGSQIP---EEALRVSSAPGPADQTTGIPTITSTSYSFGEKPIVN 1581
              H     +   ++   + +P   EE+    S+PG  + T    + T + +S    P   
Sbjct: 1441 TPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTP--- 1497

Query: 1582 YKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKE 1641
                FPD               P    T +PA  L ++ +G++   F+            
Sbjct: 1498 ----FPDS--------------PGFTHTVLPA-TLTTTDIGQESTAFHSS---------- 1528

Query: 1642 VVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFY 1676
                S A G     T  LP  ST+    G+P  FY
Sbjct: 1529 ----SDATG-----TTPLPARSTASDLVGEPTTFY 1554



 Score = 75.5 bits (184), Expect = 1e-12
 Identities = 250/1277 (19%), Positives = 423/1277 (33%), Gaps = 185/1277 (14%)

Query: 455  HSSDLRMLRMSPDTVPKAPKHLKAGDTSKGGIAKVTQSNLKSGITTT---PVDSDIGSHL 511
            HS +   +  SP      P    A   + G + + T  +   G T T   P  S    H 
Sbjct: 390  HSEESTPVHSSPVATATTPP--PARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHS 447

Query: 512  SLSLE---DLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQKTAT 568
              S       +    S+P  T    HT   +     +T    ++  ++   E +    ++
Sbjct: 448  EESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSS 507

Query: 569  PTVLSSSHSHRGK-PSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHRE 627
            P  ++++    G  PS+      P S ++  +++ +A PG   +  G+S  ++T YS   
Sbjct: 508  PDAMATTVLPAGSTPSVLVGDSTP-SPISSGSMETTALPGSTTKP-GLSEKSTTFYSSPR 565

Query: 628  KPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSH---VEDLLFFYRQTL 684
             P T +   LP S  +                +G+   S+TSHS         F    T+
Sbjct: 566  SPDTTH---LPASMTS----------------SGVSEESTTSHSRPGSTHTTAFPGSTTM 606

Query: 685  PDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKV 744
            P   L+ ++    +  GP D      T LS   +     G  Y    +    TE TL   
Sbjct: 607  PG--LSQESTASHSSPGPTD------TTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPD 658

Query: 745  SATPG-------PADQKTEIPAVQSS---SYSQREKPSILYPQDLADSHLPEEGLKVSAV 794
            + T         P    T  P    S   S +++ + +  +    ++   P      SA 
Sbjct: 659  NTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAF 718

Query: 795  AGPADQKTGLPT-VPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPA 853
              P+    G P+ +P++  S R       +++      P     +           G  +
Sbjct: 719  VEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEES 778

Query: 854  VTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPG------DQKTGIPSAPSS 907
             TS SS + ++   PS         S L EE       PG        D  T    +  S
Sbjct: 779  TTSHSSTTHTISSAPST-------TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 831

Query: 908  FYSHREKP----IIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSS 963
              SH  +     I+   ++    L  E     S +S  + + T  P  S+ +   SE+S+
Sbjct: 832  IASHSSQDATGTIVLPARSTNSVLLGEST--TSPISSGSMETTALPG-STTTPGLSERST 888

Query: 964  VFYQQ-----------ELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSH----RE 1008
             F+                 S +  ES    + PG T     P  T   G   H      
Sbjct: 889  TFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 948

Query: 1009 KPSIFYQQEWPDSYATEKALKVSTGP--GPADQKTEIPAVQSSS---------YPQREKP 1057
             P        P S  T    + +T P    + + T +P   +++         Y     P
Sbjct: 949  SPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 1008

Query: 1058 -SVLYPQVLSDSHLPEESLKVSAFPGPADQM-----TDTPAVPSTFYSQREKPGIFYQQT 1111
             + L P   + S + EES    + PG          T  P V     +    PG      
Sbjct: 1009 DTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTL 1068

Query: 1112 LPES----HLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIP- 1166
             P S     L  E+      PG + + T  P  T+ S       P +      P T +  
Sbjct: 1069 SPRSTTASSLGPESTTFHSGPG-STETTLLPDNTTASGLLEASTP-VHSSTGSPRTTLSP 1126

Query: 1167 -----EEAQKVSAVTGPGNQKTW-IPRVLSTFYSQREKPGIFYQQTLPGSHIPEEA---- 1216
                  + +  +  + P ++ T   P   ++ + +          ++P +H    +    
Sbjct: 1127 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFG 1186

Query: 1217 ----------QKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKI 1266
                        V+P   P+  ++ T      S ++   PG       P++       + 
Sbjct: 1187 RSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE 1246

Query: 1267 SVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTV 1326
            S  S     TT T +   ++ S   E+P+ ++  S P S  T      S   G +++ T 
Sbjct: 1247 SRTSH--SSTTHTISSPPSTTSALVEEPTSYH--SSPGSIATTHFPESSTTSGRSEESTA 1302

Query: 1327 IPILPST-----FYSHTEKPGVFYQQVLPHSHP-TEEALKISVASEPVDQTTGTPTVTST 1380
                P T       +H    G   +    +  P + E    S A+ P      T   +S+
Sbjct: 1303 SHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSS 1362

Query: 1381 SYSQHTEKPSIFYQQSLPG--SHLTEEAKNVSAVPGPGDRKT-GIPTLPSTFYSHTEKPG 1437
                 T  P+     S+ G  + L  +A++      P    T G+    +TF+S   KPG
Sbjct: 1363 RSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHS---KPG 1419

Query: 1438 SFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLP 1497
            S                E +++PG +  +      T+P S  G     +   +     L 
Sbjct: 1420 S---------------TETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLS 1464

Query: 1498 EESLKVSVAPGPVGQTTGAPTITSPSYSQHRAK-------SGSFYQLALLGSQIPEEALR 1550
            EES     +PG    T  + + T   +SQ           + +     L  + I +E+  
Sbjct: 1465 EESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTA 1524

Query: 1551 VSSAPGPADQTTGIPTITSTSYSFGE------KPIVNYKQAFPDGHLPEEALKVSIVSGP 1604
              S+   A  TT +P  ++ S   GE       P   Y   FP           S  SG 
Sbjct: 1525 FHSS-SDATGTTPLPARSTASDLVGEPTTFYISPSPTYTTLFPAS---------SSTSGL 1574

Query: 1605 TEKKTDIPAGPLGSSAL 1621
            TE+ T     P  +S +
Sbjct: 1575 TEESTTFHTSPSFTSTI 1591


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score =  100 bits (250), Expect = 2e-20
 Identities = 315/1434 (21%), Positives = 504/1434 (35%), Gaps = 228/1434 (15%)

Query: 475  HLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQH 534
            H    DT+ G   + T S+     +TT   S   S  S  +E+ +    SSP  T T   
Sbjct: 330  HFPESDTTSGRGEESTTSHS----STTHTISSAPSTTSALVEEPTSYH-SSPGSTATTHF 384

Query: 535  TDTLNQKTLAD----THLTEETLKVTAIPEPADQ-----KTATPTVLSSSHSHRGKPSIF 585
             D+      ++    +H +++      +P  +       ++ T  + S S      P   
Sbjct: 385  PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST 444

Query: 586  YQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEE 645
               GL +   T  +   S A  L+  +T  S ++  S + R +PG+ +    P+S  T  
Sbjct: 445  TTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTT-- 502

Query: 646  PLEVSAAPGPVEQKTGIPTVSSTSHSH--VEDLLFFYRQTLPDGHLTDQALKVSAVSGPA 703
                           G+   S+TSHS     D       T   G   +     S+ SG  
Sbjct: 503  --------------PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS-SGST 547

Query: 704  DQ--KTGTATVLS------TPHSHREKPGIFYQQEFADSHQTE---ETLTKVSATPGPAD 752
            D     G+ T LS      T HS+   PG  +   F DS  +    E  T+V ++ G + 
Sbjct: 548  DTALSPGSTTALSFGQESTTFHSN---PGSTHTTLFPDSTTSSGIVEASTRVHSSTG-SP 603

Query: 753  QKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKT-------GLP 805
            + T  PA  +S   Q E  S  +    A +H        S    P ++ T         P
Sbjct: 604  RTTLSPASSTSPGLQGE--STAFQTHPASTHTTPS--PPSTATAPVEESTTYHRSPGSTP 659

Query: 806  T----VPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTST---- 857
            T      S+   H EK  +F+         P  A   ++  G +     +P  T      
Sbjct: 660  TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLP 719

Query: 858  -SSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPI 916
             S+ +  L E  + FY    P S  T  +       G G++ T   S P S +S     +
Sbjct: 720  GSTTTPGLSEASTTFYSS--PRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS----TV 773

Query: 917  IFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLP 976
              +  T P     EE+  V + S  + + T  P  S+ +  H E+ + F+ +  P S   
Sbjct: 774  SPASTTTPG--LSEESTTVYSSSRGSTETTVFPH-STTTSVHGEEPTTFHSR--PASTHT 828

Query: 977  RESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGP 1036
                + S   GLT++ T   P  P+   +    P+     +  +   T  +   STG   
Sbjct: 829  TLFTEDSTTSGLTEESTA-FPGSPAS--TQTGLPATLTTADLGEESTTFPSSSGSTGTKL 885

Query: 1037 ADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPS- 1095
            +  ++    +   S P R  PS               S + +  PG       +P  PS 
Sbjct: 886  SPARSTTSGLVGESTPSRLSPS---------------STETTTLPG-------SPTTPSL 923

Query: 1096 -----TFY-SQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHR 1149
                 TFY S R         T   S + +E+      PG +   T  P  T+TS     
Sbjct: 924  SEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG-STHTTAFPDSTTTSDLSQE 982

Query: 1150 EKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPG 1209
               S   Q +   T  P      +  +  G Q T       TF+S    PG      LP 
Sbjct: 983  PTTSHSSQGSTEATLSPGS----TTASSLGQQST-------TFHS---SPGDTETTLLPD 1028

Query: 1210 SHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTE-KPGIFYQQVLPDNHPTEEALKISV 1268
              I     + S           TPT +S    HT   P       L +   T ++   S 
Sbjct: 1029 DTITSGLVEAS-----------TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSS 1077

Query: 1269 ASEPVDQ-TTGTPAVTSTSY-SQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTV 1326
             + P    TT  P   ST+Y S+    P+  +  S  +   +EE+  V + PG A    +
Sbjct: 1078 DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPG-ATGTAL 1136

Query: 1327 IPILPSTFY---SHTEKP---GVFYQQVLPHSHPT----EEALKISVASEPVDQTTGTPT 1376
             P   +T       T  P   G      LP S  T    E++     +    D T    +
Sbjct: 1137 FPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 1196

Query: 1377 VTSTSYSQHT----EKPSIFYQQSLPGS----HLTEEAKNVSAVPGPGDR--KTGIPTLP 1426
             TS+  S+ +     +P   +  + PGS     +++E+    + PG  D     G  T  
Sbjct: 1197 TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 1256

Query: 1427 S------TFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTP-TVTSPSSSF 1479
            S      TF+S    PGS    +LP +      LE S    PV  + G+P T  SP+ S 
Sbjct: 1257 SLGPESTTFHS---SPGSTETTLLPDNTTASGLLEAST---PVHSSTGSPHTTLSPAGST 1310

Query: 1480 GEKPIVIYKQAFPEGH--LPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQL 1537
              +      Q++P     +P      S        + G+P+ T    + H + S +    
Sbjct: 1311 TRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTP---TTHFSASSTTLGR 1367

Query: 1538 ALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALK 1597
            +   + +    +  ++ P PA  TT      ST+Y     P       FP+        +
Sbjct: 1368 SEESTTVHSSPVATATTPSPARSTTSGLVEESTAYH--SSPGSTQTMHFPESSTASGRSE 1425

Query: 1598 VSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTE 1657
             S  S  +   T I + P  +SAL E+P +++      S       + S   G +++ T 
Sbjct: 1426 ESRTSHSSTTHT-ISSPPSTTSALVEEPTSYHSSP--GSIATTHFPESSTTSGRSEESTA 1482

Query: 1658 T-----------LPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPGPDAQKT--- 1703
            +           LP H T+     +   FY   +S   +          PG  A+ T   
Sbjct: 1483 SHSSPDTNGITPLPAHFTTSGRIAESTTFY---ISPGSMETTLASTATTPGLSAKSTILY 1539

Query: 1704 ------------ETPS--------VSSSLYSYREKPIVFY-QQALPDSELTQEALKVSAV 1742
                         +PS         SSS     E+   F+   +   + ++ E+L+  A 
Sbjct: 1540 TSDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAP 1599

Query: 1743 PQPADQKTGLS-TVTSSFYSHTEKPNISYQQELPD-----SHLTEEALKVSNVP 1790
              P      L  TV  ++ + TEK N +  QE  +      +  +  LK  N+P
Sbjct: 1600 ETPEKLNATLGMTVKVTYRNFTEKMNDASSQEYQNFSTLFKNRMDVVLKGDNLP 1653



 Score = 88.6 bits (218), Expect = 1e-16
 Identities = 303/1496 (20%), Positives = 496/1496 (33%), Gaps = 244/1496 (16%)

Query: 821  FYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQ------- 873
            F + +    H  E A    + +        T A  + +S  SSLG   +  ++       
Sbjct: 3    FPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISG 62

Query: 874  --QTLPNSHLTEEALKVSIVPGPGDQKTGI-PSAPSSFYSHREKPIIFSQQTLPDFLFPE 930
              +    SH + +A+  +++P        +  S PS   S   +       T    L  +
Sbjct: 63   RSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEK 122

Query: 931  EALKVSA-----VSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDS----DLPRESLK 981
                 S+      + L A  T +     ++ SHS   S  +    P S     L +ES  
Sbjct: 123  STTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGST-HTTAFPGSTTMPGLSQESTA 181

Query: 982  MSAIPGLTDQKTVPTPTVPSG----SFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPA 1037
              + PG TD    P  T  S       +   +P        PD+      L+ S     +
Sbjct: 182  SHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSS 241

Query: 1038 DQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTP-AVPST 1096
             +        + S  ++ + +  +    S    P      SAF  P+     +P ++P+T
Sbjct: 242  TRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTT 301

Query: 1097 FYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHR------- 1149
              S R       +++      P     +           G  + TS S + H        
Sbjct: 302  HISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPST 361

Query: 1150 -----EKPSIFHQQALPG----THIPEEA----------------QKVSAVTGPGNQKTW 1184
                 E+P+ +H    PG    TH P+ +                     +  P    T 
Sbjct: 362  TSALVEEPTSYHSS--PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTS 419

Query: 1185 IPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGT---PTPTSASYS 1241
            +  +L    +     G      LPGS       + S     + +   T   P  T++S  
Sbjct: 420  V--LLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGV 477

Query: 1242 HTE------KPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGT---PAVTSTSYSQYRE 1292
              E      +PG  +    PD+  T    + S  S     +T T   PA T+TS      
Sbjct: 478  SEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS------ 531

Query: 1293 KPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHS 1352
             PS    Q   +SH +  + + +  PG     +      +TF+S+   PG  +  + P S
Sbjct: 532  GPS----QESTTSHSSSGSTDTALSPGSTTALS-FGQESTTFHSN---PGSTHTTLFPDS 583

Query: 1353 HPTEEALKISVASEPVDQTTGTPTVT---STSYSQHTEKPSIFYQQSLPGSHLTEEAKNV 1409
              +   ++   AS  V  +TG+P  T   ++S S   +  S  +Q     +H T    + 
Sbjct: 584  TTSSGIVE---ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 640

Query: 1410 SAVP---------GPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVS--- 1457
            +  P          PG   T      ST   H+EK   F+         P  A   +   
Sbjct: 641  ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 700

Query: 1458 -------VAPGPVDQT-----IGTPTVTSPSSSFGEKP----IVIYKQAFPEGHLPEESL 1501
                   ++PG  + T       TP ++  S++F   P      +   +     + EES 
Sbjct: 701  GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST 760

Query: 1502 KVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQT 1561
                 PG    T    + T+P  S                    EE+  V S+   + +T
Sbjct: 761  TSRSQPGSTHSTVSPASTTTPGLS--------------------EESTTVYSSSRGSTET 800

Query: 1562 TGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSAL 1621
            T  P  T+TS   GE+P   + +  P         + S  SG TE+ T  P  P  +   
Sbjct: 801  TVFPHSTTTSV-HGEEPTTFHSR--PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ-- 855

Query: 1622 GEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLS 1681
                 T     L  + L +E     ++ G     T+  P  ST+    G+         +
Sbjct: 856  -----TGLPATLTTADLGEESTTFPSSSGSTG--TKLSPARSTTSGLVGES--------T 900

Query: 1682 DSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFY-QQALPDSELTQEALKVS 1740
             S L   + +   +PG       TPS+S       EK   FY     PD+ L+      S
Sbjct: 901  PSRLSPSSTETTTLPG----SPTTPSLS-------EKSTTFYTSPRSPDATLSPATTTSS 949

Query: 1741 AVPQPADQKTGL--STVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTG 1798
             V + +        ST T++F   T   ++S  QE   SH ++ + + +  PG     T 
Sbjct: 950  GVSEESSTSHSQPGSTHTTAFPDSTTTSDLS--QEPTTSHSSQGSTEATLSPG----STT 1003

Query: 1799 VSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTG---INILPSNSYPQR 1855
             S++   S +    P  +    LP  T     ++    P    TG     + P++S    
Sbjct: 1004 ASSLGQQSTTFHSSPGDTETTLLPDDTITS-GLVEASTPTHSSTGSLHTTLTPASSTSAG 1062

Query: 1856 EHSVISYEQELPDLTEVTLKAIGVPG------------PADQKTGIQIASSSSYSNREKA 1903
                 +  Q  P  ++ T    G               P+   T    ASS++    E++
Sbjct: 1063 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1122

Query: 1904 SIFHQQELPDVTEEALNVFVVPGQGDRKT---EIPTVPLSYYSRREK--PSVISQQELPD 1958
            +  H    P  T  AL     P +        E  T P+S  S      P   +   L +
Sbjct: 1123 TTVHSS--PGATGTAL----FPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 1176

Query: 1959 SHLTEEALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLS 2018
               T  +   SP +  +   T    G+S   + SH       T   P    T  P  +  
Sbjct: 1177 KSTTFYSSPRSPDTTLSPAST-TSSGVSEESTTSHSRPGSTHTTAFPG--STTMPGVSQE 1233

Query: 2019 SYSQIEKP-KISTVIGPNDQKT----PSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGIL 2073
            S +    P    T + P         P  T FHSS      P       LPD   + G+L
Sbjct: 1234 STASHSSPGSTDTTLSPGSTTASSLGPESTTFHSS------PGSTETTLLPDNTTASGLL 1287

Query: 2074 KISAVPELTDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKT 2133
            + S     +  +    +S + S   + +S  F  Q  P S          T+P P     
Sbjct: 1288 EASTPVHSSTGSPHTTLSPAGSTTRQGESTTF--QSWPSSK--------DTMPAP----- 1332

Query: 2134 VLPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGT 2189
              PT   S+F              P  H +      S+ LG++++ T + + P  T
Sbjct: 1333 --PTT-TSAFVELSTTSHGSPSSTPTTHFSAS----STTLGRSEESTTVHSSPVAT 1381



 Score = 62.4 bits (150), Expect = 9e-09
 Identities = 205/1012 (20%), Positives = 338/1012 (33%), Gaps = 163/1012 (16%)

Query: 1278 GTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSH 1337
            G    ++T YS  R   +     S+ SS ++EE+    + PG            + F   
Sbjct: 118  GLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTH--------TTAFPGS 169

Query: 1338 TEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSL 1397
            T  PG+  +    HS P            P D T    + T++S       P      S 
Sbjct: 170  TTMPGLSQESTASHSSP-----------GPTDTTLSPGSTTASSLG-----PEYTTFHSR 213

Query: 1398 PGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHT--EKPGSFYQQVLPHS-HLPEEAL 1454
            PGS  TE           G  +  +P   ST   HT     GS  +Q    + H    + 
Sbjct: 214  PGS--TETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSK 271

Query: 1455 EVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPG------ 1508
            +   AP         P+ TS  S        I  ++   G L EES     +PG      
Sbjct: 272  DTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSG-LVEESTTYHSSPGSTQTMH 330

Query: 1509 -PVGQTT---GAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGI 1564
             P   TT   G  + TS S + H   S      AL+     EE     S+PG +  TT  
Sbjct: 331  FPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALV-----EEPTSYHSSPG-STATTHF 384

Query: 1565 PTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSA---- 1620
            P  +ST+    E+   ++      G +   A   + V       + I +G + ++A    
Sbjct: 385  PD-SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 443

Query: 1621 -----LGEKPITFYRQ-----------ALLDSPLNKEVVKVSAAPG-------PADQKTE 1657
                 L E+  TF+             +   S +++E     + PG       P    T 
Sbjct: 444  TTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTP 503

Query: 1658 TLPVHS-TSYSNRGKPVIFY----------QQTLSDSHLPEEALKVPPVPGPDAQKTETP 1706
             L  HS TS+S+ G                 Q  + SH    +      PG     T   
Sbjct: 504  GLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPG----STTAL 559

Query: 1707 SVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHT--- 1763
            S      ++   P   +    PDS  +   ++ S         TG    T S  S T   
Sbjct: 560  SFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEAST---RVHSSTGSPRTTLSPASSTSPG 616

Query: 1764 -EKPNISYQQELPDSHLTEEALKVSNVP---------GPADQKTGVSTVTSTSYSHREKP 1813
             +  + ++Q     +H T      +  P          P    T     +ST+  H EK 
Sbjct: 617  LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS 676

Query: 1814 IVSYQR--------ELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQ--REHSVISYE 1863
             + +             H T +G         +   T I  LP ++      E S   Y 
Sbjct: 677  TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 736

Query: 1864 QELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFV 1923
                  T ++  ++   G  ++ T  +    S++S    AS       P ++EE+  V+ 
Sbjct: 737  SPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS----TTTPGLSEESTTVYS 792

Query: 1924 VPGQGDRKTEIP---------TVPLSYYSR-REKPSVISQQELPDSHLTEEALKVSPVSI 1973
                    T  P           P +++SR     + +  ++   S LTEE+        
Sbjct: 793  SSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP--GS 850

Query: 1974 PAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIG 2033
            PA  +TG+P  L+++                  ++ T FP+++ S+ +++  P  ST  G
Sbjct: 851  PASTQTGLPATLTTADL---------------GEESTTFPSSSGSTGTKL-SPARSTTSG 894

Query: 2034 PNDQKTPSQTAFHSSYSQTV------------KPNILFQQQLPDRDQSKGILKISAVPEL 2081
               + TPS+ +  S+ + T+                    + PD   S      S V E 
Sbjct: 895  LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 954

Query: 2082 TDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTVLPTALPS 2141
            +  +  +P S  ++ F    +     QE   SH ++   + +  PG     T   +    
Sbjct: 955  SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPG----STTASSLGQQ 1010

Query: 2142 SFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGTYSHG 2193
            S +    P       LPD  +T   ++ S+    +         P+ + S G
Sbjct: 1011 STTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 1062



 Score = 41.6 bits (96), Expect = 0.017
 Identities = 107/540 (19%), Positives = 180/540 (33%), Gaps = 80/540 (14%)

Query: 1698 PDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTS 1757
            PDA  T      S+       P V    + P S ++  +++ +A+P  +  K GLS  ++
Sbjct: 74   PDAMATTVLPAGST-------PSVLVGDSTP-SPISSGSMETTALPG-STTKPGLSEKST 124

Query: 1758 SFYSHTEKPNISY-QQELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVS 1816
            +FYS    P+ ++    +  S ++EE+    + PG        ST T+        P +S
Sbjct: 125  TFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPG--------STHTTAFPGSTTMPGLS 176

Query: 1817 YQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDLTEVTLKA 1876
             +    H +         PGP D      + P ++         +     P  TE TL  
Sbjct: 177  QESTASHSS---------PGPTD----TTLSPGSTTASSLGPEYTTFHSRPGSTETTLLP 223

Query: 1877 IGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRKTEIPT 1936
                      +G+  AS   +S+            P  T          G+    T   +
Sbjct: 224  DNTTA-----SGLLEASMPVHSSTRS---------PHTTLSPAGSTTRQGE---STTFHS 266

Query: 1937 VPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEK 1996
             P S  +R   P+  S    P +        +    I A   T   +  S++Y   H   
Sbjct: 267  WPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTY---HSSP 323

Query: 1997 LKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPN 2056
                T+H P+   T       ++        IS+            T++HSS   T   +
Sbjct: 324  GSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH 383

Query: 2057 ILFQQQLPDRDQSKGILKISAVPELTDVNTG---------KPVSLSSSYFHREKSNIFSP 2107
                   PD   + G  + S     +   TG           V L  S      S     
Sbjct: 384  ------FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 437

Query: 2108 QELPGSHVTEDVLKVSTI--PGPAGQKTVLPTALPS-------SFSHREKPDIFYQKDLP 2158
              LPGS  T  + + ST     P    T L  A  +       S + R +P   +    P
Sbjct: 438  TALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFP 497

Query: 2159 DRHLTEDALKISSALGQADQITGLQTVPSGTYSHGENHKLVSEHVQRLIDNLNSSDSSVS 2218
            D   T    + S+    +   T    +P+ T + G + +  + H      +  S+D+++S
Sbjct: 498  DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSH-----SSSGSTDTALS 552


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 399/1840 (21%), Positives = 651/1840 (35%), Gaps = 293/1840 (15%)

Query: 419  KVESDVITLDGLNENAVVCSERVAELQRKPTRESEYHSSDLRMLRMSP-DTVPKAPKHLK 477
            +  S   T DG +      SE    L   P       SS+   L  +P D+  +     +
Sbjct: 1550 QASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTE 1609

Query: 478  AGDTSKGGIAKVTQSNLKSG--------ITTTPVDSDIGSHLSLSLED-----LSQLAVS 524
            A  ++    + +T S    G        ++TTPV S   S LS +  D     ++   VS
Sbjct: 1610 ASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVS 1669

Query: 525  SPLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTV-----LSSSHSHR 579
            S      G    T +  T   T LT  T++ T +   A    +T  V     +++S   R
Sbjct: 1670 SSPTPAEGTSMPT-STYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEAR 1728

Query: 580  GKPSIFYQQGLPDSHLTE-----EALKVSAAPGLADQTTGMS-------TLTSTSYSHRE 627
              P+      +P+S  +E      ++ VS  P L+ + + +S       T  +TS     
Sbjct: 1729 SSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATS 1788

Query: 628  KPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDG 687
             P T     +P S L+E    +++ P               SH+ V +       T P  
Sbjct: 1789 SPTTAEGTSIPTSTLSEGMTPLTSTP--------------VSHTLVANSEASTLSTTPVD 1834

Query: 688  HLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSAT 747
                  +  +AVS       GT+   STP                 +  T   ++  +  
Sbjct: 1835 S-NSPVVTSTAVSSSPTPAEGTSIATSTPSE-------------GSTALTSIPVSTTTVA 1880

Query: 748  PGPADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTV 807
                +  +  PAV S+       P   Y Q ++ S    +G  +   + P + +  L ++
Sbjct: 1881 SSETNTLSTTPAVTST-------PVTTYAQ-VSSSPTTADGSSMPT-STPREGRPPLTSI 1931

Query: 808  PSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGP--ADGKT-GTPAVTSTSSASSSL 864
            P S  +     +      L D+  P       A S P  ADG +  TPA +  S+  +S+
Sbjct: 1932 PVSTTTVASSEINTLSTTLADTRTPVTTYS-QASSSPTTADGTSMPTPAYSEGSTPLTSM 1990

Query: 865  GEKPSAFYQQTLPNSHLTEEALKVSIVP----GPGDQKTGIPSAPSSFYSHREKPIIFSQ 920
                +           ++ EA  +S  P     P    T   S+P++      +    S+
Sbjct: 1991 PLSTTLV---------VSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSE 2041

Query: 921  QTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESL 980
            +T P    P     VS   V++++     T   +S +    S+        +      S 
Sbjct: 2042 RTTPLAGMP-----VSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISA 2096

Query: 981  KMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQK 1040
                 P LT   ++P  T P  S       +       P   +TE    VS+ P P    
Sbjct: 2097 PSEGSPLLT---SIPLSTTPVASPEASTLSTTPVDSNSPVITSTE----VSSSPIP---- 2145

Query: 1041 TEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQ 1100
            TE  ++Q+S+Y  R  P    P  +S + +   ++   +   P D  T TP   ST    
Sbjct: 2146 TEGTSMQTSTYSDRRTPLTSMP--VSTTVVASSAISTLSTT-PVD--TSTPVTNST--EA 2198

Query: 1101 REKPGIFYQQTLP-----ESHLPKEALKISVAPGLADQKT---GTPTVTSTSYSQHREKP 1152
            R  P      ++P     E   P  ++ +S  P +  + +    TP  TST  +   E  
Sbjct: 2199 RSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEAT 2258

Query: 1153 SIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHI 1212
            S        GT IP     +S  T P    T IP V  T  +  E   +    T   S+ 
Sbjct: 2259 S--SPTTAEGTSIPTST--LSEGTTP---LTSIP-VSHTLVANSEVSTL--STTPVDSNT 2308

Query: 1213 PEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKIS---VA 1269
            P      +    P  + T  PT TS+                  N P    + +S   VA
Sbjct: 2309 PFTTSTEASSPPPTAEGTSMPTSTSSE----------------GNTPLTR-MPVSTTMVA 2351

Query: 1270 SEPVDQTTGTPAVTST---SYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTV 1326
            S      + TPA TST   +YSQ    P+     S+P+S  +E +  +++VP      + 
Sbjct: 2352 SFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVP-----VST 2406

Query: 1327 IPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHT 1386
            +P++ S   +H+  P       +  S P   + + S  S P   TT   T   TS     
Sbjct: 2407 MPVVSSEASTHSTTP-------VDTSTPVTTSTEAS--SSP---TTAEGTSIPTSPPSEG 2454

Query: 1387 EKPSIFYQQSLPGSH---LTEEAKNVSAVP----GPGDRKTGIPTLPSTFYS-----HTE 1434
              P      S+P S    ++ EA  +S  P     P    T   + P+T         T 
Sbjct: 2455 TTP----LASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTA 2510

Query: 1435 KPGSFYQQVLPHSHLPEEALEVS-VAPGPVDQTIGTPTVTS---PSSSFGEKPIVIYKQA 1490
              GS     +P S  P  + E S ++  PVD    +P VTS    SS+   +   +    
Sbjct: 2511 SEGSTLLTSIPVSTTPVASPEASTLSTTPVDS--NSPVVTSTEISSSATSAEGTSMPTST 2568

Query: 1491 FPEGHLPEESLKVSVAP-----------GPVGQTTGAPTITSPSYSQHRAKSGSF----- 1534
            + EG  P  S+ VS  P            PV  +    T T  S S   AK  S      
Sbjct: 2569 YSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTP 2628

Query: 1535 -----YQLALLGSQIPEEALRVSS-APGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPD 1588
                    ++L S +P  +   S+ +  P D  T + T T TS S    P      + P 
Sbjct: 2629 SEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSS----PTTAEGSSMPT 2684

Query: 1589 GHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALG-EKPITFYRQALLDSPLNKEVVKVSA 1647
                E +  ++ +   T    +  A  L ++ +    P+T   +A   SP   E   +  
Sbjct: 2685 STPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEA-SSSPTTAEGTSMRI 2743

Query: 1648 APGPADQKT-------ETLPVHSTSYSNRGKPVIFYQQTLSDSHLP----EEALKVPPVP 1696
            +  P+D  T        TLPV S+  S           T  D+ +P     EA   P   
Sbjct: 2744 ST-PSDGSTPLTSILVSTLPVASSEAST-------VSTTAVDTSIPVTTSTEASSSPTTA 2795

Query: 1697 GPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVT 1756
               +  T TPS +S+       P+     A      + EA  +S    P D  T ++T T
Sbjct: 2796 EVTSMPTSTPSETST--PLTSMPVNHTPVA------SSEAGTLSTT--PVDTSTPVTTST 2845

Query: 1757 SSFYSHTEKPNISYQQELPDSHLTEEALKVSNVP-GPADQKTGVSTVTSTSYSHREKPIV 1815
             +  S T    I     +P S  +E +  ++++P       +  ++  ST+      P+ 
Sbjct: 2846 KASSSPTTAEGI----VVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVT 2901

Query: 1816 SYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYP--QREHSVISYEQELPDLTEVT 1873
            +        T A    + +  P++  T +  +  ++ P    E S +S    +   T VT
Sbjct: 2902 TSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLS-TTPVDTRTPVT 2960

Query: 1874 LKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRKTE 1933
              A     P   + G  +  S+    R   +      +P  + EA  +   P        
Sbjct: 2961 TSAEASSSPTTAE-GTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVT 3019

Query: 1934 IPTVPLSYYSRREKPSV-ISQQELPDSHLTEEALKVSPVSIP-AEQKTGIPIG------- 1984
              T   S  +  E   + IS      + LT   +  +PV+IP A   +  P+        
Sbjct: 3020 TSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVT 3079

Query: 1985 ---LSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTV-IGPNDQKTP 2040
               +SSS + +    + IST        T  P +T    + +    IST+   P D  TP
Sbjct: 3080 STEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVST----TPVTSSAISTLSTTPVDTSTP 3135

Query: 2041 SQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVP--------------ELTDVNT 2086
              T+  +  S T          +P    S+G   ++ +P                T V+T
Sbjct: 3136 VTTSTEAHSSPTTSEG----TSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDT 3191

Query: 2087 GKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIP 2126
              PV+ S+       S       +P S  +E +  ++++P
Sbjct: 3192 STPVTTST---EATSSTTAEGTSIPTSTPSEGMTPLTSVP 3228



 Score = 94.7 bits (234), Expect = 2e-18
 Identities = 425/2055 (20%), Positives = 702/2055 (34%), Gaps = 367/2055 (17%)

Query: 226  DLPLLTCLTQDQEFAPDSLFHQSELSF----APLRGIPDKSEDTEWS-SRPSEVSEALFQ 280
            ++P+ T L    E +  S       +F    +     P  +EDT  + S PSE S  L  
Sbjct: 397  NMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTS 456

Query: 281  ---ATAEVASDLASSRFSVSQHPLIGSTAVGSQCPFLPSEQGNNEETISSVDELKIPKDC 337
               +T  VAS  AS+         + +T V S+     S + ++    + V+ +      
Sbjct: 457  MPVSTTPVASSEASN---------LSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS 507

Query: 338  DRYDDLCSYMSWKTRKDTQWPENNLADKDQVSVATSFDITDENIATKRSDHFDAARSYGQ 397
            +    L S MS  T        + L+      V TS  +T  + A+  S           
Sbjct: 508  EGSTPLTS-MSVSTMPVASSEASTLST---TPVDTSTPVTTSSEASSSST---------- 553

Query: 398  YWTQEDSSKQAETYLTKGLQGKVESDVITLDGLNENAVVCSERVAELQRKPTRESEYHSS 457
              T E +S    T  ++G        V T   ++  A   S   A+     T  SE  SS
Sbjct: 554  --TPEGTSIPTSTP-SEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSS 610

Query: 458  DLRMLRMSPDTVPKAPKHLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLED 517
                   S  T   + +      TS      +  S+  S ++TTPVDS+     S     
Sbjct: 611  STTAEGTSMPTSTYSERGTTI--TSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATS 668

Query: 518  LSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHS 577
             S  A  + + T+T     T       +T L   +   T    P D  T+TP   S+  S
Sbjct: 669  SSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVD--TSTPVTTSTEAS 726

Query: 578  HRGKPSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQEL 637
                P+      +P S  +E +  +++ P         + LTS+  S      T     L
Sbjct: 727  --SSPTTADGASMPTSTPSEGSTPLTSMP------VSKTLLTSSEAS------TLSTTPL 772

Query: 638  PESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVS 697
              S       E S +P   E  T +P  + +  S +               LT   + ++
Sbjct: 773  DTSTHITTSTEASCSPTTTE-GTSMPISTPSEGSPL---------------LTSIPVSIT 816

Query: 698  AVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEI 757
             V+ P       +T+ +TP                DS+    T T+VS++P PA + T +
Sbjct: 817  PVTSPE-----ASTLSTTP---------------VDSNSPVTTSTEVSSSPTPA-EGTSM 855

Query: 758  PAVQSSSYSQREKPSILYPQDL------ADSHLPEEGLKVSAVAGPADQKTGLPT----- 806
            P   +S+YS+   P    P         A S L    +  S     + +    PT     
Sbjct: 856  P---TSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGT 912

Query: 807  -VPSSAYSHREKLLVFYQQALLDSHLP---EEALKVSAVSGPADGKTGTPAVTSTSSASS 862
             +P+S        L     ++ DS  P    EA  +SA   P D  T TP  TST + SS
Sbjct: 913  SMPTSTPGEGSTPLT----SMPDSTTPVVSSEARTLSAT--PVD--TSTPVTTSTEATSS 964

Query: 863  SLGEKPSAFYQQT----------LPNSH---LTEEALKVSIVP----GPGDQKTGIPSAP 905
                + ++    T           P SH      EA  +S  P     P    T   S P
Sbjct: 965  PTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPP 1024

Query: 906  SSFYSHREKPIIFSQQTLPDFLFPEEALKV--SAVSVLAAQKTGTPTVSSNSHSHSEKSS 963
             +           S+ + P    P     V  S  S L+     T T  +     S  S+
Sbjct: 1025 PTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSST 1084

Query: 964  VFYQQELPDSDLPRESLKMSAIPGLT------DQKTVPTPTVPSGSFSHREKPSIFYQQE 1017
                  +P S     S  ++++P  T      +  T+ T  V +          +    E
Sbjct: 1085 TADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSI-------PVTTSTE 1137

Query: 1018 WPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKV 1077
               S  T +   + T P P++  T + ++  S+       +        DS     +   
Sbjct: 1138 ASSSPTTAEGTSIPTSP-PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE 1196

Query: 1078 SAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLP---KEALKISVAPGLADQK 1134
            ++ P P  ++T   ++P++   +R  P      ++P  H P    EA  +S +P      
Sbjct: 1197 ASSPPPTAEVT---SMPTSTPGERSTP----LTSMPVRHTPVASSEASTLSTSP----VD 1245

Query: 1135 TGTPTVTSTSYSQHREKPSIFHQQALPG----------THIPEEAQKVSA------VTGP 1178
            T TP  TS   S     P+     +LP           T IP     V++      +T P
Sbjct: 1246 TSTPVTTSAETS---SSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTP 1302

Query: 1179 GNQKTWIPRVLSTFYSQREKP--------GIFYQQTLPGSHIPEE----AQKVSPVLG-- 1224
             + K   P V S   S    P          + +   P + IP      A     +L   
Sbjct: 1303 VDTKG--PVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTT 1360

Query: 1225 PADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKIS--------VASEPVDQT 1276
            P D  T   T T A  S T   G      +P+++P+E    ++        V S      
Sbjct: 1361 PVDNSTPVTTSTEACSSPTTSEG----TSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTL 1416

Query: 1277 TGTPAVTS---TSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVP--------------- 1318
            + TP  TS   T+ ++    P+     S+P+S  +E    + ++P               
Sbjct: 1417 SATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLS 1476

Query: 1319 -GPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKI--------SVASEPVD 1369
              P D  +  P++ ST  S +  P       +  S P+E +  +        +VAS  ++
Sbjct: 1477 TTPVDSNS--PVVTSTAVSSSPTPAEGTSIAI--STPSEGSTALTSIPVSTTTVASSEIN 1532

Query: 1370 QTTGTPTVTS---TSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVP------------- 1413
              + TP VTS   T+YSQ +  P+     S+  S  +E +  ++++P             
Sbjct: 1533 SLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANT 1592

Query: 1414 ---GPGDRKTGIPTLP----------STFYSHTEKPGSFYQQVLPHSHLPEEALEVS-VA 1459
                P D KT +              S+    T   GS     +P S  P  + E S ++
Sbjct: 1593 LSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLS 1652

Query: 1460 PGPVDQTIGTPTVTSPSSSFGEKP---IVIYKQAFPEGHLPEESLKVSVAP--------- 1507
              PVD    +P +TS   S    P     +    + EG  P  S+ V   P         
Sbjct: 1653 TTPVDS--NSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTL 1710

Query: 1508 --GPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAP---------- 1555
               PV  +T   T T    S   ++  S           P  ++ VS+ P          
Sbjct: 1711 STTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS 1770

Query: 1556 -GPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAG 1614
              P D +T + T T  + S    P      + P   L E    ++          +  A 
Sbjct: 1771 ATPIDTSTPVTTSTEATSS----PTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEAS 1826

Query: 1615 PLGSSALGEKPITFYRQALLDSPLNKEVVKV-SAAPGPADQKTETLPVHSTSYSN----- 1668
             L ++ +          A+  SP   E   + ++ P        ++PV +T+ ++     
Sbjct: 1827 TLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNT 1886

Query: 1669 -------RGKPVIFYQQ------TLSDSHLPEEA-------LKVPPVPGPDAQKTETPSV 1708
                      PV  Y Q      T   S +P          L   PV       +E  ++
Sbjct: 1887 LSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTL 1946

Query: 1709 SSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNI 1768
            S++L   R  P+  Y QA   S  T +    +++P PA    G + +TS   S T     
Sbjct: 1947 STTLADTR-TPVTTYSQA-SSSPTTADG---TSMPTPA-YSEGSTPLTSMPLSTT----- 1995

Query: 1769 SYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELPHFTE-- 1826
                      ++ EA  +S    P D  T  +T T  S S       S Q   P      
Sbjct: 1996 --------LVVSSEASTLSTT--PVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTP 2045

Query: 1827 -AGLKILRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQ 1885
             AG+ +      + +   ++  P +S  Q  +S  +      + + +T+ A     P   
Sbjct: 2046 LAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLT 2105

Query: 1886 KTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRR 1945
               +     +S      ++       P +T   ++   +P      TE  ++  S YS R
Sbjct: 2106 SIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIP------TEGTSMQTSTYSDR 2159

Query: 1946 EKPSVISQQELPDSHLTEEALKVSPVS-IPAEQKTGIPIGLSSSYSHSHKEKLKISTVHI 2004
              P       +P S     +  +S +S  P +  T +     +  S +  E   + T   
Sbjct: 2160 RTPLT----SMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT-ST 2214

Query: 2005 PDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLP 2064
            P +  T F +  +S+   +     +    P D  TP  T+  ++ S T          +P
Sbjct: 2215 PSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEG----TSIP 2270

Query: 2065 DRDQSKGILKISAVP 2079
                S+G   ++++P
Sbjct: 2271 TSTLSEGTTPLTSIP 2285



 Score = 88.6 bits (218), Expect = 1e-16
 Identities = 374/1811 (20%), Positives = 604/1811 (33%), Gaps = 289/1811 (15%)

Query: 496  SGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKV 555
            S ++TTPVDS+     S         A  + + T+T    +T   +    T +       
Sbjct: 2297 STLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETS 2356

Query: 556  TAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGM 615
            T    PAD  T   T   +  S    P+      +P S  +E +  +++ P      + M
Sbjct: 2357 TLSTTPADTSTPVTTYSQAGSS----PTTADDTSMPTSTYSEGSTPLTSVP-----VSTM 2407

Query: 616  STLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVED 675
              ++S + +H   P        P +  TE     + A G     T IPT  S        
Sbjct: 2408 PVVSSEASTHSTTP---VDTSTPVTTSTEASSSPTTAEG-----TSIPT--SPPSEGTTP 2457

Query: 676  LLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSH 735
            L      T P   ++ +A  +S    P D  T   T      S      I      A   
Sbjct: 2458 LASMPVSTTP--VVSSEAGTLSTT--PVDTSTPMTTSTEASSSPTTAEDIVVPISTASEG 2513

Query: 736  QTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVA 795
             T  T   VS TP  + + + +      S S      ++   +++ S    EG  +   +
Sbjct: 2514 STLLTSIPVSTTPVASPEASTLSTTPVDSNS-----PVVTSTEISSSATSAEGTSM-PTS 2567

Query: 796  GPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGK-----TG 850
              ++  T L ++P S                +D+ +P         S P   K       
Sbjct: 2568 TYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIP-VTTSTETSSSPTTAKDTSMPIS 2626

Query: 851  TPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGI--PSAPSSF 908
            TP+  STS  S  +   P A  + +  ++   +    V+   G     T     S P+S 
Sbjct: 2627 TPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTST 2686

Query: 909  YSHREKPI--IFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFY 966
               R  P+  I    TL   L   EA  +S   V  +    T   +S+S + +E +S+  
Sbjct: 2687 PGERSTPLTNILVSTTL---LANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRI 2743

Query: 967  QQELPDSDLPRESLKMSAIP-GLTDQKTVPTPTVPSG-----SFSHREKPSIFYQQEWPD 1020
                 D   P  S+ +S +P   ++  TV T  V +      S      P+       P 
Sbjct: 2744 STP-SDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPT 2802

Query: 1021 SYATEKALKVSTGP----------------GPADQKTEI-PAVQSSSYPQREKPSVLYPQ 1063
            S  +E +  +++ P                 P D  T +  + ++SS P   +  V+   
Sbjct: 2803 STPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIS 2862

Query: 1064 VLSDSHLPEESLKVSAFP---GPADQMTDTP---AVPSTFYSQ-REKPGIFYQQTLP--- 1113
              S+      S+ VS  P     A  ++ TP   ++P T  ++    P      ++P   
Sbjct: 2863 TASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIST 2922

Query: 1114 --ESHLPKEALKISVAP---GLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEE 1168
              E   P  ++ +S  P     A   + TP  T T  +   E  S        GT +P  
Sbjct: 2923 PSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASS--SPTTAEGTSMP-- 2978

Query: 1169 AQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQ 1228
                  ++ PG ++T +  +  +              T+P +    EA  +S    PAD 
Sbjct: 2979 ------ISTPGERRTPLTSMSVS--------------TMPVA--SSEASTLSRT--PADT 3014

Query: 1229 KTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKI----------------SVASEP 1272
             T   T T AS S T   G      +P + P+E +  +                ++++ P
Sbjct: 3015 STPVTTSTEASSSPTTAEG----TGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTP 3070

Query: 1273 VDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVP-------------- 1318
            VD  + +P VTST  S     P+     S+P S  +E +  ++ VP              
Sbjct: 3071 VD--SNSPVVTSTEVS---SSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTL 3125

Query: 1319 --GPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKIS---------VASE- 1366
               P D  T +        S T   G      +P S P+E +  ++         V+SE 
Sbjct: 3126 STTPVDTSTPVTTSTEAHSSPTTSEGT----SMPTSTPSEGSTPLTYMPVSTMLVVSSED 3181

Query: 1367 ------PVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTE-EAKNVSAVPGPGDRK 1419
                  PVD  T TP  TST  +  T         S P   +T   +  VS  P      
Sbjct: 3182 STLSATPVD--TSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEA 3239

Query: 1420 TGIPTLP-------STFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTV 1472
            + + T P       +T    +  P +     +P S   E +  ++  P        + T 
Sbjct: 3240 SILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETS 3299

Query: 1473 T-SPSSSFGEKPIVIYKQA----------------FPEGHLPEESLKVSVAP-------- 1507
            T S + +    P+  Y QA                + EG  P  ++  S  P        
Sbjct: 3300 TLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEAST 3359

Query: 1508 ---GPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGI 1564
                PV  +T   T T  S S   A+  S    +      P  ++ VS+ P  + +   +
Sbjct: 3360 LSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTL 3419

Query: 1565 P-------TITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLG 1617
                    T+ +TS      P +    + P     E +  +SI+   T       A  L 
Sbjct: 3420 STTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLS 3479

Query: 1618 SSALGEKPITFYRQALLDSPLNKEVVKV-SAAPGPADQKTETLPVHSTSYSNRGKPVIFY 1676
            ++ +              SP   EV  + ++  G        +PV +T  ++     +  
Sbjct: 3480 TTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLST 3539

Query: 1677 QQTLSDSHL--PEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQ 1734
                S++ +    +A   P        +  TPS  SS  +            L  + +T 
Sbjct: 3540 TPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLT---------TMLLSSTYVTS 3590

Query: 1735 EALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLT-------------- 1780
                  + P   D+ T ++T T S  + T    I+     P    T              
Sbjct: 3591 SEASTPSTPS-VDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTI 3649

Query: 1781 EEALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQ 1840
             EA   S +  P D  T V T T  S S    P+      +P +T           P++ 
Sbjct: 3650 SEAGTASTL--PVDTSTPVITSTQVSSS----PVTPEGTTMPIWT-----------PSEG 3692

Query: 1841 KTGINILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNR 1900
             T     P  + P     V S E         TL    V       T  +  SSS+  + 
Sbjct: 3693 ST-----PLTTMPVSTTRVTSSEGS-------TLSTPSVVTSTPVTTSTEAISSSATLDS 3740

Query: 1901 EKASIFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSH 1960
               S+    E+  +    L V   P     ++  P++P  Y S     S+ +  E   S 
Sbjct: 3741 TTMSVSMPMEISTLGTTIL-VSTTPVTRFPESSTPSIPSVYTSM----SMTTASEGSSSP 3795

Query: 1961 LTEEALKVSPVSIPAEQKTGIPIGLSSSYS-HSHKEKLKISTVHIPDDQKTEFPAATLSS 2019
             T E     P+S  +E+ T +   L S  S  S  E   +ST   P D  T  P  T + 
Sbjct: 3796 TTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTP--PGDTST--PLLTSTK 3851

Query: 2020 YSQIEKPKISTVIG---PNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKIS 2076
                  P   T I     +++ TP  T   S+   T  P        P  D S      +
Sbjct: 3852 AGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASI-ASTPPLDTSTTFTPST 3910

Query: 2077 AVPELTDVNTGKPVSLS-SSYFHREKSNIFSPQELPGSHVTEDVLKVST--IPGPAGQKT 2133
                   +     +S+S  +      + IF P   P +  T DV   +T  +  P    T
Sbjct: 3911 DTASTPTIPVATTISVSVITEGSTPGTTIFIP-STPVTSSTADVFPATTGAVSTPVITST 3969

Query: 2134 VLPTALPSSFS 2144
             L T   SS S
Sbjct: 3970 ELNTPSTSSSS 3980



 Score = 83.6 bits (205), Expect = 4e-15
 Identities = 375/1753 (21%), Positives = 608/1753 (34%), Gaps = 342/1753 (19%)

Query: 496  SGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKV 555
            S ++ TPVD+      S     L   A ++ + T+T     T        T L   +   
Sbjct: 352  STLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEAS 411

Query: 556  TAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTE-EALKVSAAPGLADQTTG 614
            T    P D KT   T   +S S             P    T   ++ VS  P  + + + 
Sbjct: 412  TTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASN 471

Query: 615  MSTL-------TSTSYSHREKPGTFYQQELPESNLTE-----EPLEVSAAP--------- 653
            +ST         +TS      P T     +P S  +E       + VS  P         
Sbjct: 472  LSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTL 531

Query: 654  --GPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTAT 711
               PV+  T + T S  S S           T P+G     +      +   +    T  
Sbjct: 532  STTPVDTSTPVTTSSEASSS----------STTPEGTSIPTSTPSEGSTPLTNMPVSTRL 581

Query: 712  VLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGP----ADQKTEIPAVQSSSYSQ 767
            V+S+  S               S +   + T    T  P    +++ T I ++  S+   
Sbjct: 582  VVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLV 641

Query: 768  REKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALL 827
                +        DS+ P      +  +    + T +PT   S Y+     L       +
Sbjct: 642  ASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPT---STYTEGSTPLT---SMPV 695

Query: 828  DSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALK 887
            ++ L   +   +  + P D  T TP  TST ++SS     P+     ++P S        
Sbjct: 696  NTTLVASSEASTLSTTPVD--TSTPVTTSTEASSS-----PTTADGASMPTS-------- 740

Query: 888  VSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTG 947
                  P +  T + S P S             +TL   L   EA  +S   +  +    
Sbjct: 741  -----TPSEGSTPLTSMPVS-------------KTL---LTSSEASTLSTTPLDTSTHIT 779

Query: 948  TPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLT-DQKTVPTPTVPSGSFSH 1006
            T T +S S + +E +S+        S L   S+ +S  P  + +  T+ T  V S S   
Sbjct: 780  TSTEASCSPTTTEGTSMPISTPSEGSPL-LTSIPVSITPVTSPEASTLSTTPVDSNS--- 835

Query: 1007 REKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLS 1066
                        P + +TE    VS+ P PA + T +P   +S+Y +   P    P    
Sbjct: 836  ------------PVTTSTE----VSSSPTPA-EGTSMP---TSTYSEGRTPLTSMP---V 872

Query: 1067 DSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLP-----ESHLPKEA 1121
             + L   S   +    P D  T TP   ST    R  P      ++P     E   P  +
Sbjct: 873  STTLVATSAISTLSTTPVD--TSTPVTNST--EARSSPTTSEGTSMPTSTPGEGSTPLTS 928

Query: 1122 LKISVAPGLADQK---TGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGP 1178
            +  S  P ++ +    + TP  TST  +   E            T  P  A+  S  T  
Sbjct: 929  MPDSTTPVVSSEARTLSATPVDTSTPVTTSTE-----------ATSSPTTAEGTSIPTST 977

Query: 1179 GNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSH---IPEEAQKVSPVLGPADQKTGTPTP 1235
             ++ T    + ST                P SH      EA  +S    P D  T   T 
Sbjct: 978  PSEGT--TPLTST----------------PVSHTLVANSEASTLSTT--PVDSNTPLTTS 1017

Query: 1236 TSASYSHTEKPGIFYQQVLPDNHPTEEALKIS--------VASEPVDQTTGTPAVTS--- 1284
            T AS      P       +P + P+E +  ++        VAS      + TPA TS   
Sbjct: 1018 TEAS----SPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPV 1073

Query: 1285 TSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVP----------------GPADQKTVIP 1328
            T+YSQ     +     S+P+S  +E +  +++VP                 P D  T IP
Sbjct: 1074 TTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVD--TSIP 1131

Query: 1329 ILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQT----TGTPTVTSTSYSQ 1384
            +  ST    +  P       +P S P+E    +  AS PV  T    +   T+++T    
Sbjct: 1132 VTTST--EASSSPTTAEGTSIPTSPPSEGTTPL--ASMPVSTTLVVSSEANTLSTTPVDS 1187

Query: 1385 HTEKPSIFYQQSLPGSHLTEEAKNVSAVP--GPGDRKTGIPTLPSTFYSHTEKPGSFYQQ 1442
             T+  +     S P          V+++P   PG+R T + ++P                
Sbjct: 1188 KTQVATSTEASSPP------PTAEVTSMPTSTPGERSTPLTSMPV--------------- 1226

Query: 1443 VLPHSHLPEEALEVS-VAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESL 1501
                 H P  + E S ++  PVD +  TP  TS  +S    P      + P     E S 
Sbjct: 1227 ----RHTPVASSEASTLSTSPVDTS--TPVTTSAETS--SSPTTAEGTSLPTSTTSEGST 1278

Query: 1502 KVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEE-----ALRVSSAPG 1556
             ++  P           +TSP  S             LL + +  +     +  VSS+P 
Sbjct: 1279 LLTSIP------VSTTLVTSPEAS------------TLLTTPVDTKGPVVTSNEVSSSPT 1320

Query: 1557 PADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVS-GPTEKKTDI---- 1611
            PA+ T+ +PT T   YS G  P+     + P       +  +SI+S  P +  T +    
Sbjct: 1321 PAEGTS-MPTST---YSEGRTPLT----SIPVNTTLVASSAISILSTTPVDNSTPVTTST 1372

Query: 1612 -----PAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAA----PGPADQKTE-TLPV 1661
                 P    G+S     P +     L   P++   V  S A      P D  T  T   
Sbjct: 1373 EACSSPTTSEGTSMPNSNP-SEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSA 1431

Query: 1662 HSTSYSNRGKPVIFYQQTLSDSHLPEEALKV--PPVPGPDAQKTETPSVSSSLYSYREKP 1719
             +TS     + +     T S+   P +++ V   PV   +A    T  V S+       P
Sbjct: 1432 EATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSN------SP 1485

Query: 1720 IVFYQQALPDSELTQEALKVSAVPQPADQKTGLST--VTSSFYSHTEKPNISYQQELPDS 1777
            +V    A+  S    E   + A+  P++  T L++  V+++  + +E  ++S    +  +
Sbjct: 1486 VV-TSTAVSSSPTPAEGTSI-AISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTST 1543

Query: 1778 HLTEEALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGP 1837
             +T  + + S+ P  AD   G S  TST YS    P+ S          +    L    P
Sbjct: 1544 PVTTYS-QASSSPTTAD---GTSMQTST-YSEGSTPLTSLPVSTMLVVSSEANTLSTT-P 1597

Query: 1838 ADQKTGINI---LPSNSYPQREHSVISYEQE-LPDLTEVTLKAIGVPGPADQKTGIQIAS 1893
             D KT +       S++  +     IS   E  P LT + +    V  P           
Sbjct: 1598 IDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVD 1657

Query: 1894 SSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQ 1953
            S+S               P +T   ++    P +G   T +PT   +Y   R   + I+ 
Sbjct: 1658 SNS---------------PVITSTEVSSSPTPAEG---TSMPT--STYTEGRTPLTSITV 1697

Query: 1954 QELPDSHLTEEALKVSPV--SIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTE 2011
            +  P +      L  +PV  S P    T       SS + S    +  ST   P +  T 
Sbjct: 1698 RTTPVASSAISTLSTTPVDNSTPVTTST----EARSSPTTSEGTSMPNST---PSEGTTP 1750

Query: 2012 FPAATLSSYSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKG 2071
              +  +S+   +     +    P D  TP  T+  ++ S T          +P    S+G
Sbjct: 1751 LTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEG----TSIPTSTLSEG 1806

Query: 2072 ILKISAVPELTDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPAGQ 2131
            +  +++ P            +S +     +++  S   +  +        VS+ P PA +
Sbjct: 1807 MTPLTSTP------------VSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPA-E 1853

Query: 2132 KTVLPTALPSSFS 2144
             T + T+ PS  S
Sbjct: 1854 GTSIATSTPSEGS 1866



 Score = 68.2 bits (165), Expect = 2e-10
 Identities = 291/1394 (20%), Positives = 473/1394 (33%), Gaps = 236/1394 (16%)

Query: 488  KVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTH 547
            K   S+  S ++TTPVD+ I    S         A  + +  +T     T     L  T 
Sbjct: 2584 KPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTM 2643

Query: 548  LTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEALKVSAAPG 607
                +   T    P D +T   T   +S S    P+      +P S   E +  ++    
Sbjct: 2644 PVASSEASTLSTTPVDTRTLVTTSTGTSSS----PTTAEGSSMPTSTPGERSTPLT---- 2695

Query: 608  LADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSS 667
                    + L ST+     +  T     +  S       E S++P   E   G     S
Sbjct: 2696 --------NILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAE---GTSMRIS 2744

Query: 668  TSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIFY 727
            T       L      TLP              S  A   + TA   S P        +  
Sbjct: 2745 TPSDGSTPLTSILVSTLP------------VASSEASTVSTTAVDTSIP--------VTT 2784

Query: 728  QQEFADSHQTEETLTKVSATPGPADQK-TEIPAVQSSSYSQREKPSILYPQDLADSHLPE 786
              E + S  T E  +  ++TP       T +P   +   S         P D +      
Sbjct: 2785 STEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTP---- 2840

Query: 787  EGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVS-GPA 845
              +  S  A  +        VP S  S    LL     ++  S  P  + + S +S  P 
Sbjct: 2841 --VTTSTKASSSPTTAEGIVVPISTASEGSTLLT----SIPVSTTPVASSEASTLSTTPV 2894

Query: 846  DGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAP 905
            D  T  P  TST  +SS    + ++    T         ++ VS VP  G + + + + P
Sbjct: 2895 D--TSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTP 2952

Query: 906  -------SSFYSHREKPIIFSQQTLP-----DFLFPEEALKVSAVSVLAAQ--------- 944
                   ++       P      ++P     +   P  ++ VS + V +++         
Sbjct: 2953 VDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPA 3012

Query: 945  KTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSF 1004
             T TP  +S   S S  ++      +P S     S  +++IP  T    +P  +  S + 
Sbjct: 3013 DTSTPVTTSTEASSSPTTA--EGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTP 3070

Query: 1005 SHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQV 1064
                 P +              + +VS+ P PA + T +P    S+Y +   P    P  
Sbjct: 3071 VDSNSPVV-------------TSTEVSSSPTPA-EGTSMPI---STYSEGSTPLTGVPV- 3112

Query: 1065 LSDSHLPEESLKVSAF-PGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALK 1123
               S  P  S  +S     P D  T TP   ST       P      ++P S   + +  
Sbjct: 3113 ---STTPVTSSAISTLSTTPVD--TSTPVTTST--EAHSSPTTSEGTSMPTSTPSEGSTP 3165

Query: 1124 ISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKT 1183
            ++  P             ST      E  ++        T +    +  S+ T  G   T
Sbjct: 3166 LTYMP------------VSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEG---T 3210

Query: 1184 WIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPV-LGPADQKTGTPTPTSASYSH 1242
             IP       +     G+    ++P S+ P  + + S +   P D  T   T T AS S 
Sbjct: 3211 SIP-------TSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSP 3263

Query: 1243 TEKPGIFYQQVLPDNHPTEEALKI--------SVASEPVDQTTGTPAVTS---TSYSQYR 1291
                G      +P + P+E +  +        +VAS      + TPA TS   T+YSQ  
Sbjct: 3264 PTAEG----TSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQAS 3319

Query: 1292 EKPSIFYQQSLPSSHLTE------------------EAKNVSAVPGPADQKTVIPILPST 1333
              P I    S+P+S  +E                  EA  +S    P D  T +      
Sbjct: 3320 SSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTT--PVDTSTPVTTSTEA 3377

Query: 1334 FYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFY 1393
              S T   G      +P S P+E    +  AS PV   + TP V+S   +  T       
Sbjct: 3378 SLSPTTAEGT----SIPTSSPSEGTTPL--ASMPV---STTPVVSSEVNTLST------- 3421

Query: 1394 QQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEA 1453
               +  + L   +   S+ P   +  T +PT        T   GS    ++P S  P  +
Sbjct: 3422 -TPVDSNTLVTTSTEASSSPTIAE-GTSLPT-------STTSEGSTPLSIMPLSTTPVAS 3472

Query: 1454 LEVS-VAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFP-----EGHLPEESLKVSVAP 1507
             E S ++  PVD    T T  + SS     P      + P     EG  P  ++ VS   
Sbjct: 3473 SEASTLSTTPVD----TSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTT- 3527

Query: 1508 GPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSS-APGPADQTTGIPT 1566
             PV  +  +   T+P  S     S S  Q +   + +    +R+S+ + G +  TT + +
Sbjct: 3528 -PVASSEASTLSTTPVDSNTFVTSSS--QASSSPATLQVTTMRMSTPSEGSSSLTTMLLS 3584

Query: 1567 ---ITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGE 1623
               +TS+  S    P V       D   P   +  S  S  T    ++   P+ + +   
Sbjct: 3585 STYVTSSEASTPSTPSV-------DRSTP---VTTSTQSNSTPTPPEVITLPMSTPSEVS 3634

Query: 1624 KPITFYRQALLDSPLNKEVVKVS----AAPGPADQKTETL---PVHSTSYSNRGKPVIFY 1676
             P+T         P++   V +S    A+  P D  T  +    V S+  +  G  +  +
Sbjct: 3635 TPLTI-------MPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIW 3687

Query: 1677 QQTLSDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEA 1736
              +   + L    +    V   +     TPSV +S       P+    +A+  S  T ++
Sbjct: 3688 TPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTS------TPVTTSTEAI-SSSATLDS 3740

Query: 1737 LKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQK 1796
              +S V  P +  T  +T+  S    T  P  S    +P  + +      S         
Sbjct: 3741 TTMS-VSMPMEISTLGTTILVSTTPVTRFPE-SSTPSIPSVYTSMSMTTASEGSSSPTTL 3798

Query: 1797 TGVSTVTSTSYSHR 1810
             G +T+  ++ S R
Sbjct: 3799 EGTTTMPMSTTSER 3812



 Score = 59.3 bits (142), Expect = 8e-08
 Identities = 290/1378 (21%), Positives = 474/1378 (34%), Gaps = 209/1378 (15%)

Query: 162  EMDSSQTLDTSQTRFNVRTEDTEVTDFPSLEEGILTQSENQVKEP---NRDLFCSPL--- 215
            E+ S  T   S+T   + +     T   S E G L+ +      P   +     SP    
Sbjct: 2796 EVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAE 2855

Query: 216  -LVIQDSFASPDLPLLTCLTQDQEFAPDSLFHQSELSFAPLRGIPDKSEDTEWSSRPS-- 272
             +V+  S AS    LLT +       P +    S LS  P+      +  TE SS P+  
Sbjct: 2856 GIVVPISTASEGSTLLTSIPVST--TPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTA 2913

Query: 273  EVSEALFQATAEVASDLASSRFSV-----SQHPLIGSTAVGSQCPFLPSEQGNNEETISS 327
            E +       +EV++ L S   S      S+   + +T V ++ P   S + ++  T + 
Sbjct: 2914 EGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAE 2973

Query: 328  VDELKIPKDCDRYDDLCSYMSWKTRKDTQWPENNLADKDQVSVATSFDITDENIATKRSD 387
               + I    +R   L S MS  T        + L+   +    TS  +T    +T+ S 
Sbjct: 2974 GTSMPISTPGERRTPLTS-MSVSTMPVASSEASTLS---RTPADTSTPVTT---STEASS 3026

Query: 388  HFDAARSYGQYWT--QEDSSKQAETYLTKGLQGKVESDVITLDGLNENAVVCSERVAELQ 445
                A   G   +   E S+      ++       E+  ++   ++ N+ V +    E+ 
Sbjct: 3027 SPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTS--TEVS 3084

Query: 446  RKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKAGDTSKGGIAKVTQSNLKSGITTTPVDS 505
              PT       + + +   S  + P     +     +   I+ ++ + +    T+TPV +
Sbjct: 3085 SSPTPAE---GTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVD---TSTPVTT 3138

Query: 506  DIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQK 565
               +H S +  + + +  S+P E +T      +   T+      + TL  T +       
Sbjct: 3139 STEAHSSPTTSEGTSMPTSTPSEGSTP--LTYMPVSTMLVVSSEDSTLSATPVDTSTPVT 3196

Query: 566  TATPTVLSSSHSHRGKPSIFYQQGL------PDSHL---TEEALKVSAAPGLADQTTGMS 616
            T+T    S++      P+    +G+      P S+    + EA  +S  P   D  T ++
Sbjct: 3197 TSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTP--VDSNTPLT 3254

Query: 617  TLTSTSYSHREKPGTFYQQELPESN---LTEEPLEVSAAPG---------PVEQKTGIPT 664
            T T  S S     GT      P      LT  P+  +             P +  T + T
Sbjct: 3255 TSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTT 3314

Query: 665  VSSTSHSH-VEDLLFFYRQTLPDGH--LTDQALKVSAV---------SGPADQKTGTATV 712
             S  S S  + D       T  +G   LT+ +   + V         + P D  T   T 
Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTS 3374

Query: 713  LSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATP-----------GPADQKTEIPAVQ 761
                 S     G            T      VS TP            P D  T +    
Sbjct: 3375 TEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTST 3434

Query: 762  SSSYSQREKPSILYPQDLADSHLPEEGLKVSAV----------------AGPADQKTGLP 805
             +S S    P+I     L  S   E    +S +                  P D  T + 
Sbjct: 3435 EASSS----PTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVT 3490

Query: 806  TV-PSSAYSHREKLLVFYQQALLDSHLPEEALKVSAV---SGPADGKTGTPA-----VTS 856
            T  P+++     ++         +   P   + VS     S  A   + TP      VTS
Sbjct: 3491 TSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTS 3550

Query: 857  TSSASSSLGEKPSAFYQQTLPN---SHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHRE 913
            +S ASSS         + + P+   S LT   L  + V      +   PS PS     R 
Sbjct: 3551 SSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTS---SEASTPSTPSV---DRS 3604

Query: 914  KPIIFSQQTLPDFLFPEE-ALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELP- 971
             P+  S Q+      PE   L +S  S ++   T  P VS+ S + SE  +      LP 
Sbjct: 3605 TPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMP-VSTTSVTISEAGTA---STLPV 3660

Query: 972  DSDLPR-ESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKP-SIFYQQEWPDSYATEKALK 1029
            D+  P   S ++S+ P   +  T+P  T   GS      P S         S  +  ++ 
Sbjct: 3661 DTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVV 3720

Query: 1030 VSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTD 1089
             ST   P    TE  A+ SS+       SV  P  +S       ++ VS  P      + 
Sbjct: 3721 TST---PVTTSTE--AISSSATLDSTTMSVSMPMEISTLGT---TILVSTTPVTRFPESS 3772

Query: 1090 TPAVPSTFYSQREKPG---------IFYQQTLPESHL-------------------PKEA 1121
            TP++PS + S               +    T+P S                     P EA
Sbjct: 3773 TPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEA 3832

Query: 1122 LKISVAPGLADQKTGTPTVTST---SYSQHRE----KPSIFHQQALPGTHIPEEAQKVSA 1174
              +S  PG     T TP +TST   S+S   E    + SI  +++ P T +       ++
Sbjct: 3833 STLSTPPG----DTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTS 3888

Query: 1175 VTGPGNQKTWIPRVLSTFYSQREK---PGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTG 1231
              G     T      +TF    +    P I    T+  S I E +   + +  P+     
Sbjct: 3889 FPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPS----- 3943

Query: 1232 TPTPTSASYSHTEKPGIFYQQVLPD---NHPTEEALKISVASEPVDQTTGTPAVTSTSYS 1288
            TP  +S +       G     V+     N P+  +   + +     + T TPA+T+ +  
Sbjct: 3944 TPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFT-TPAMTTAAPL 4002

Query: 1289 QYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVI--PILPSTFYSHTEKPGVFYQ 1346
             Y    +        S   T  A  +SA   P    +V   P+ PS   S + +P     
Sbjct: 4003 TYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPS---SESSRPSTITS 4059

Query: 1347 QVLPHSHPT------------------EEALKISVASEPVDQTTGTPTVTSTSYSQHT 1386
              +P + P                   E    ++  ++P  +TT  PTVT+T+   +T
Sbjct: 4060 HTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNT 4117



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 235/1180 (19%), Positives = 403/1180 (34%), Gaps = 188/1180 (15%)

Query: 499  TTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKVTAI 558
            T+TPV +   +  S +  + + + +S+P E +T   +  ++   +A      E   ++  
Sbjct: 3014 TSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVA----IPEASTLSTT 3069

Query: 559  PEPADQKTATPTVLSSSHSHR---GKPSIFYQQG---LPDSHLTEEALKVSAAPGLADQT 612
            P  ++    T T +SSS +       P   Y +G   L    ++   +  SA   L+   
Sbjct: 3070 PVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTP 3129

Query: 613  TGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAP----------------GPV 656
               ST  +TS      P T     +P S  +E    ++  P                 PV
Sbjct: 3130 VDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPV 3189

Query: 657  EQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTP 716
            +  T + T +  + S   +       T  +G     ++ VS     + +    A++LST 
Sbjct: 3190 DTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSE----ASILSTT 3245

Query: 717  HSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYP 776
                  P +    E + S  T E  +  ++TP           V +++ +  E  ++   
Sbjct: 3246 PVDSNTP-LTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTT 3304

Query: 777  QDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEAL 836
               AD+  P      ++ + P    T +PT   S  S     + F    ++ S    EA 
Sbjct: 3305 P--ADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSS----EAS 3358

Query: 837  KVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTE-----EALKVSIV 891
             +S    P D  T TP  TST ++ S     P+     ++P S  +E      ++ VS  
Sbjct: 3359 TLSTT--PVD--TSTPVTTSTEASLS-----PTTAEGTSIPTSSPSEGTTPLASMPVSTT 3409

Query: 892  PGPGDQKTGIPSAP-------SSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQ 944
            P    +   + + P       ++       P I    +LP     E +  +S + +    
Sbjct: 3410 PVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPL---- 3465

Query: 945  KTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSF 1004
             + TP  SS       ++S      +  S     S   ++ P   +  ++PT T   GS 
Sbjct: 3466 -STTPVASS-------EASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGST 3517

Query: 1005 SHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAV-QSSSYPQR--------- 1054
                 P            A+ +A  +ST P   D  T + +  Q+SS P           
Sbjct: 3518 PLTNMPVS------TTPVASSEASTLSTTP--VDSNTFVTSSSQASSSPATLQVTTMRMS 3569

Query: 1055 ---EKPSVLYPQVLSDSHLPEESLKVSAFPG--------PADQMTDTPAVPSTFYSQREK 1103
               E  S L   +LS +++        + P          + Q   TP  P         
Sbjct: 3570 TPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMST 3629

Query: 1104 PGIFYQQTLPESHLPKEALKISVAP-GLADQ---KTGTPTVTSTSYSQHREKPS------ 1153
            P    + + P + +P     ++++  G A      T TP +TST  S     P       
Sbjct: 3630 PS---EVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPI 3686

Query: 1154 -IFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHI 1212
                + + P T +P    +V++  G        P V+++         I    TL  + +
Sbjct: 3687 WTPSEGSTPLTTMPVSTTRVTSSEG---STLSTPSVVTSTPVTTSTEAISSSATLDSTTM 3743

Query: 1213 PEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEP 1272
                      LG     + TP       S    P ++             ++ ++ ASE 
Sbjct: 3744 SVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVY------------TSMSMTTASEG 3791

Query: 1273 VDQTTGTPAVTSTSYSQYREKPSIFYQQSL-PSSHLT-EEAKNVSAVPGPADQKTVIPIL 1330
                T     T+   S   E+ ++     + P S ++  EA  +S  PG     T  P+L
Sbjct: 3792 SSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGD----TSTPLL 3847

Query: 1331 PSTFYSHTEKPG-------------------VFYQQVLPHSHP-----TEEALKISVASE 1366
             ST       P                    +     LP S P     +   L  S    
Sbjct: 3848 TSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFT 3907

Query: 1367 PVDQTTGTPTV---TSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNV-----SAVPGPGDR 1418
            P   T  TPT+   T+ S S  TE  +      +P + +T    +V      AV  P   
Sbjct: 3908 PSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVIT 3967

Query: 1419 KTGIPTLPSTFYSHTEKPGSFYQQVLPHSHL---PEEALEVSVAPGPVDQTIGTPTVTSP 1475
             T + T PST  S T    S  ++    +     P   + +S AP        TP  TS 
Sbjct: 3968 STELNT-PSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPS-------TPRTTSR 4019

Query: 1476 SSSFGEKPIVIYKQAFPEGHLPEESLKVSVAP-GPVGQTTGAPTITSPSYSQHRAKSGSF 1534
              +     +            P  S  V+  P  P  +++   TITS +       + S 
Sbjct: 4020 GCTTSASTLSATST-------PHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSS 4072

Query: 1535 YQLALLGSQI---PEEALRVSSAPGPADQTTGIPTITSTS 1571
                   S     PE    +++   P+ +TT  PT+T+T+
Sbjct: 4073 TPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTA 4112



 Score = 44.3 bits (103), Expect = 0.003
 Identities = 171/881 (19%), Positives = 291/881 (33%), Gaps = 143/881 (16%)

Query: 1352 SHPTEEALKISVASEP--VDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNV 1409
            ++P   +++ SV S+   V  T  TPT + T+    ++  ++F   +   S  T      
Sbjct: 87   TNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTD 146

Query: 1410 SAVPGPGDRKTG-----IPTLP-STFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPV 1463
              +  P +         + T P  +F ++T    S   +V   + L       S    P 
Sbjct: 147  VPMSTPSEESISSTMAFVSTAPLPSFEAYT----SLTYKVDMSTPLTTSTQASSSPTTPE 202

Query: 1464 DQTIGTPTVTSPSSSFGEKPIVIYKQAFPEG-HLPEESLKVSVAPGPVGQTTGAPTITSP 1522
              TI   T +  S+     P    K A  E   L    +++S       Q + +PT    
Sbjct: 203  STTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEG 262

Query: 1523 SYSQHRAKSGSFYQLALLGSQI----PEEALRVSSAPGPADQTTGIPTITSTSYSFGEKP 1578
                + A SG    L  +   +      EA  +S+ P      T IP ITST  S     
Sbjct: 263  PSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPA----ATNIPVITSTEASSSPTT 318

Query: 1579 IVNYK---QAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSAL-------GEKPITF 1628
                      + +G  P  +   S +   T + + +   P+ +S L          P T 
Sbjct: 319  AEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTA 378

Query: 1629 YRQALLDS-------PLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLS 1681
               ++L S       PL    V            T T+PV S ++            T  
Sbjct: 379  EATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAE 438

Query: 1682 DSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSA 1741
            D+ +          P      + TP  SS                        EA  +S 
Sbjct: 439  DTSIATSTPSEGSTPLTSMPVSTTPVASS------------------------EASNLST 474

Query: 1742 VPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTE-----EALKVSNVPGPADQK 1796
               P D KT ++T T +    +  P  +    +P S  +E      ++ VS +P  + + 
Sbjct: 475  T--PVDSKTQVTTSTEA----SSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSE- 527

Query: 1797 TGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQRE 1856
               ST+++T          S +      T  G  I     P++  T     P  + P   
Sbjct: 528  --ASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSI-PTSTPSEGST-----PLTNMPVST 579

Query: 1857 HSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTE 1916
              V+S E      T           PAD  T +  +S +S S+                 
Sbjct: 580  RLVVSSEASTTSTT-----------PADSNTFVTTSSEASSSS----------------- 611

Query: 1917 EALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAE 1976
                            E  ++P S YS R   ++ S         + EA  +S   + + 
Sbjct: 612  -------------TTAEGTSMPTSTYSER-GTTITSMSVSTTLVASSEASTLSTTPVDSN 657

Query: 1977 QKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPND 2036
                     +SS + +    +  ST        T  P  T +  +  E   +ST   P D
Sbjct: 658  TPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT-TLVASSEASTLSTT--PVD 714

Query: 2037 QKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVNTGKPVSLSSSY 2096
              TP  T+  +S S T          +P    S+G   ++++P    + T    S  S+ 
Sbjct: 715  TSTPVTTSTEASSSPTTADG----ASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTT 770

Query: 2097 FHREKSNIFSPQELPGSHVTED--VLKVSTIPGPAGQKTVLPTALPSSFSHREKPDIFYQ 2154
                 ++I +  E   S  T +   + +ST      + + L T++P S +    P+    
Sbjct: 771  PLDTSTHITTSTEASCSPTTTEGTSMPIST----PSEGSPLLTSIPVSITPVTSPEASTL 826

Query: 2155 KDLP--DRHLTEDALKISSALGQADQITGLQTVPSGTYSHG 2193
               P         + ++SS+   A+      ++P+ TYS G
Sbjct: 827  STTPVDSNSPVTTSTEVSSSPTPAEG----TSMPTSTYSEG 863


>gi|52145312 hypothetical protein LOC118611 [Homo sapiens]
          Length = 699

 Score = 96.7 bits (239), Expect = 4e-19
 Identities = 62/153 (40%), Positives = 91/153 (59%), Gaps = 5/153 (3%)

Query: 4013 DGRGYLAGPGREAGRDLLRPFVRATLQESLQFHRPDFISRSGERIKRLKLIVQERKLQSM 4072
            DG G   G   +       P    TLQE+L+  +P FISRS ER+K+L+ +VQ+RK Q  
Sbjct: 548  DGAGS-PGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRK 606

Query: 4073 LQT-ERDALFNIDRERQGHQNRMCPLPKRVFLAIQKNKPISKKEMIQRSKRIYEQLPEVQ 4131
                ++ +L  I   R   +    P P    L   K + IS+KEM  RSKRIY+ LPEV+
Sbjct: 607  EDLRQKQSLLPI---RTSKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYDNLPEVK 663

Query: 4132 KKREEEKRKSEYKSYRLRAQLYKKRVTNQLLGR 4164
            KK+EE++++   +S RLRA+++KK++ +QLL R
Sbjct: 664  KKKEEQRKRVILQSNRLRAEVFKKQLLDQLLQR 696


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 87.4 bits (215), Expect = 3e-16
 Identities = 389/1805 (21%), Positives = 614/1805 (34%), Gaps = 298/1805 (16%)

Query: 485   GIAKVTQSNLKSGITTTPVDSDIGS-HL--SLSLEDLSQLAVSSPLETTTGQHTDT---L 538
             G  K   S   S +T T   S  GS HL  S   +  S    SSP      Q+T+    +
Sbjct: 10168 GFRKTNMSLDTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDI 10227

Query: 539   NQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEE 598
                  A   +TE T  +T+ PE       T +V  S+H             LP +     
Sbjct: 10228 ITPFNASPSITEST-GITSFPE----SRFTMSVTESTHH-------LSTDLLPSAETIST 10275

Query: 599   ALKVSAAPGLADQTTGMSTL--------TSTSYSHREK-PGTFYQQELPESNLTEEPLEV 649
                 +  P L++  T  +T         + + +S  E  PG      + ES  +  P+  
Sbjct: 10276 G---TVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPF 10332

Query: 650   SAAPGPVEQKTGIP-----TVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPAD 704
             S++       + IP     T SS +   V+  L     T     +    L  S+  G   
Sbjct: 10333 SSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPG--- 10389

Query: 705   QKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSS 764
              +T ++ +L T  +   + G         ++Q     T+++ T G  +  T+IP    ++
Sbjct: 10390 -RTSSSPILDTRMTESVELGTV-----TSAYQVPSLSTRLTRTDGIMEHITKIP--NEAA 10441

Query: 765   YSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYS-HREKLLVFYQ 823
             +    +P +  PQ       P+ GL            T L T  ++  +  R  L     
Sbjct: 10442 HRGTIRP-VKGPQTSTSPASPK-GLHTGGTKRMETTTTALKTTTTALKTTSRATLTTSVY 10499

Query: 824   QALLDSHLPEEALKVSAVSGPADGKTGTPAV-----TSTSSASSSLGEKPSAFYQQTLPN 878
                L +  P  A    A + P +    TP V      +TSS ++SLG + S    +T P+
Sbjct: 10500 TPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGAETSTALPRTTPS 10559

Query: 879   SHLTEEALKVSIVPGPGDQKTGI----------PSAPSSFYSHREKPIIFSQQTLPDFLF 928
                 E     S+V   G +++ +          P   +S+  H  + I    +T P+F  
Sbjct: 10560 VFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVSKTTPNFFH 10619

Query: 929   PEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGL 988
              E                   TVSS + SH    S      +  S+L   +  +  I G 
Sbjct: 10620 SE-----------------LDTVSSTATSHGADVSSAIPTNISPSELDALT-PLVTISGT 10661

Query: 989   TDQKTVPTPTVPSGS-------FSHREKPSIFYQQEWPD--SYATEKALKVSTGPGPADQ 1039
                 T PT T             +H  + S    +  P+   + ++    ++T PG A+ 
Sbjct: 10662 DTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPG-AET 10720

Query: 1040  KTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYS 1099
              + IP +  S  P  E   ++  QV S     + ++ +         +T +P  P T  S
Sbjct: 10721 SSAIPIMTVS--PGAE--DLVTSQVTSSG--TDRNMTIPT-------LTLSPGEPKTIAS 10767

Query: 1100  QREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQA 1159
                 P     +    S +P   +  +V+  +    T     TST+       P       
Sbjct: 10768 LVTHP-----EAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSPG------ 10816

Query: 1160  LPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKV 1219
                    E A  VS VT P      +P   S F+  +         T P       A+  
Sbjct: 10817 -------EPATTVSLVTHPAQTSPTVPWTTSIFFHSKS-------DTTPSMTTSHGAESS 10862

Query: 1220  SPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGT 1279
             S V          PTPT +    TE PG+    V      T     IS     +  + G 
Sbjct: 10863 SAV----------PTPTVS----TEVPGVVTPLV------TSSRAVISTTIPILTLSPGE 10902

Query: 1280  PAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSA---VPGPADQKTVIPIL------ 1330
             P  T +  + + E+ S     ++P+  ++     V         A   T IPIL      
Sbjct: 10903 PETTPSMATSHGEEAS----SAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGE 10958

Query: 1331  ----PSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHT 1386
                 PS   SH  + G     VLP       +L   VAS     +T  PT+T +     T
Sbjct: 10959 PETTPSMATSHGTEAGSAVPTVLPEVPGMVTSL---VASSRAVTSTTLPTLTLSPGEPET 11015

Query: 1387  EKPSIFYQQSLPGSHLTEEAKNVSAV----PG---------PGDRKTGIPTLPSTFYSHT 1433
                      S+  SH  E +  V  V    PG          G   T IPTL  +     
Sbjct: 11016 TP-------SMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELE 11068

Query: 1434  EKPGSFYQQVLPHSHLPEEALEV---SVAPGPVDQTIGTPTVTSPSSSFGEK-PIVIYKQ 1489
               P       +  SH  E +  V   +V+PG     + TP VTS  +      PI+    
Sbjct: 11069 TTPS------MATSHGAEASSAVPTPTVSPGV--SGVVTPLVTSSRAVTSTTIPILTLSS 11120

Query: 1490  AFPE-------GHLPEESLKV-SVAPGPVGQTTGA------------PTITSPSYSQHRA 1529
             + PE        H  E S  V +V+P   G  T              PT+T  S      
Sbjct: 11121 SEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETT 11180

Query: 1530  KSGSFYQLALLGSQIPE-------EALRVSSAPGPADQTTGIPTITSTSY------SFGE 1576
              S   +  A + S IP        + L  S       +T+    +T  S       S+  
Sbjct: 11181 TSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPETIDSWVA 11240

Query: 1577  KPIVNYKQAFPDGHLP--EEALKVSIVSGPTEKKTDIP--AGPLGSSALGEKPITFYRQA 1632
              P        P   +   E    +S+V+ P E  + +P        S L   P T     
Sbjct: 11241 HPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPST----- 11295

Query: 1633  LLDSPLNKEVVKVSAAPGPADQKTETLPVHST----SYSNRGKPVIFYQQTLSDSHLPEE 1688
              + SP  +    +S    P      T  V S+    S +    P   ++   + S +   
Sbjct: 11296 -VTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHP 11354

Query: 1689  ALKVPPVPG--PDAQKTE---TPSVSSS--LYSYREKPIVFYQQALPD---SELTQEALK 1738
             A+    VP   P+   +E   TPS+++S    +  + P +     +PD   S++T     
Sbjct: 11355 AVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTD 11414

Query: 1739  VSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTG 1798
              S         +G    T+SF +++E    S    LP S    + L    +    D  T 
Sbjct: 11415 TSITIPTLTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTT 11474

Query: 1799  VSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILR-VPGPADQKTGINILPSNSYPQRE- 1856
               T+T T Y      I     +L H  E    + R  P  +  K+   +  + + P  E 
Sbjct: 11475 FPTLTETPYEPETTAI-----QLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEA 11529

Query: 1857  HSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKAS-IFHQQELPDVT 1915
              S +S     PD++++    +   G  D  T     S + Y     A+ + H  E     
Sbjct: 11530 SSAVSTTTISPDMSDLVTSLVPSSG-TDTSTTFPTLSETPYEPETTATWLTHPAETSTTV 11588

Query: 1916  EEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELP---DSHLTEEALKVSPVS 1972
                +  F   G  D    + T P    +R   P+      +P    S +T  A   S   
Sbjct: 11589 SGTIPNFSHRG-SDTAPSMVTSP-GVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAI 11646

Query: 1973  IPAEQKTGIPIGLSSSYSHSHKE---KLKISTV----------HIPDDQKTEFPAATLSS 2019
                    G P   +SS +H   +    + I TV           +    +T  P +  +S
Sbjct: 11647 PTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTS 11706

Query: 2020  YSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVP 2079
                   P  + V+      T  +T   S+   T+ P     + +  +  S G    + VP
Sbjct: 11707 SFSHSSPDATPVMA-----TSPRTEASSAVLTTISPGA--PEMVTSQITSSGAATSTTVP 11759

Query: 2080  ELTDVNTGKP--VSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTVLPT 2137
              LT  + G P   +L S++   E S  F P       V+E    ++  PG A   T LPT
Sbjct: 11760 TLTH-SPGMPETTALLSTHPRTETSKTF-PASTVFPQVSETTASLTIRPG-AETSTALPT 11816

Query: 2138  ALPSS 2142
                SS
Sbjct: 11817 QTTSS 11821



 Score = 85.1 bits (209), Expect = 1e-15
 Identities = 415/2019 (20%), Positives = 694/2019 (34%), Gaps = 358/2019 (17%)

Query: 234   TQDQEFAPDSLFHQSELSF-APLRGIPDKSEDTEWSSRP-SEVSEALFQATAEVASDLAS 291
             T   ++ P S + +  +    P    P  +E T  +S P S  + ++ ++T  +++DL  
Sbjct: 10209 TSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMSVTESTHHLSTDLLP 10268

Query: 292   SRFSVSQHPLIGSTAV---------------GSQCPFLPSEQGNNEETISSVDELKIPKD 336
             S  ++S   ++ S +                GS  PF  +E G  + T+S++ E      
Sbjct: 10269 SAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGDATLSTIAE------ 10322

Query: 337   CDRYDDLCSYMSWKTRKDTQWPENNLADKDQVSVATSFDITDENIATKRSDHFDAARSYG 396
                        S  +     +  +     D  ++    +IT  +    R D      S  
Sbjct: 10323 -----------SLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESS- 10370

Query: 397   QYWTQEDSSKQAETYLTKGLQGKVESDVITLDGLNEN----AVVCSERVAELQRKPTR-- 450
                T E       T  T    G+  S  I    + E+     V  + +V  L  + TR  
Sbjct: 10371 ---TTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTD 10427

Query: 451   ----------ESEYHSSDLRMLR-MSPDTVPKAPKHLKAGDTSKGGIAKVTQSNLKSGIT 499
                           H   +R ++     T P +PK L  G T +    + T + LK+  T
Sbjct: 10428 GIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKR---METTTTALKT--T 10482

Query: 500   TTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHL----TEETLKV 555
             TT + +   + L+ S+     L   +PL  +  Q   T+  + +  T        ET   
Sbjct: 10483 TTALKTTSRATLTTSVY-TPTLGTLTPLNASM-QMASTIPTEMMITTPYVFPDVPETTSS 10540

Query: 556   TAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGM 615
              A    A+  TA P         R  PS+F +    +S  T   +  S     A+++  +
Sbjct: 10541 LATSLGAETSTALP---------RTTPSVFNR----ESETTASLVSRSG----AERSPVI 10583

Query: 616   STLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVED 675
              TL  +S     +P T     +  +    E +   +   P    + + TVSST+ SH  D
Sbjct: 10584 QTLDVSS----SEPDTTASWVIHPA----ETIPTVSKTTPNFFHSELDTVSSTATSHGAD 10635

Query: 676   LLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPH-SHREKPGIFYQQEFAD- 733
             +       +    L D    +  +SG  D  T   T+  +PH +      + +  E +  
Sbjct: 10636 VSSAIPTNISPSEL-DALTPLVTISG-TDTSTTFPTLTKSPHETETRTTWLTHPAETSST 10693

Query: 734   --------SHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLP 785
                     SH   +    ++ +PG A+  + IP +  S  +          +DL  S + 
Sbjct: 10694 IPRTIPNFSHHESDATPSIATSPG-AETSSAIPIMTVSPGA----------EDLVTSQVT 10742

Query: 786   EEGLKVSAVAGPADQKTGLPTVPSSAYSHRE-KLLVFYQQALLDSHLPEEALKVSAVSGP 844
               G          D+   +PT+  S    +    LV + +A   S +P   +       P
Sbjct: 10743 SSG---------TDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTI------SP 10787

Query: 845   ADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSA 904
             A  +  T  VTS ++ +S+          + L NS   E A  VS+V  P      +P  
Sbjct: 10788 AVSRLVTSMVTSLAAKTSTT--------NRALTNSP-GEPATTVSLVTHPAQTSPTVPWT 10838

Query: 905   PSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSN---------S 955
              S F+  +         T P       A   SAV         TPTVS+          +
Sbjct: 10839 TSIFFHSK-------SDTTPSMTTSHGAESSSAVP--------TPTVSTEVPGVVTPLVT 10883

Query: 956   HSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQ 1015
              S +  S+      L   + P  +  M+   G      +PTPTV  G       P +   
Sbjct: 10884 SSRAVISTTIPILTLSPGE-PETTPSMATSHGEEASSAIPTPTVSPG------VPGVVTS 10936

Query: 1016  QEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESL 1075
                     T   + + T      + T   A    +      P+V          LPE   
Sbjct: 10937 LVTSSRAVTSTTIPILTFSLGEPETTPSMATSHGTEAGSAVPTV----------LPEVPG 10986

Query: 1076  KVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKT 1135
              V++    +  +T T  +P+   S  E       +T P       A   S  P ++ +  
Sbjct: 10987 MVTSLVASSRAVTST-TLPTLTLSPGE------PETTPSMATSHGAEASSTVPTVSPEVP 11039

Query: 1136  G--TPTVTSTSYSQHREKPSIF----HQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVL 1189
             G  T  VTS+S       P++       +  P       A+  SAV  P    T  P V 
Sbjct: 11040 GVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTP----TVSPGVS 11095

Query: 1190  STFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIF 1249
                             T+P   +     + +P +  +    G    ++      E PG+ 
Sbjct: 11096 GVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMATSH---GVEASSAVLTVSPEVPGMV 11152

Query: 1250  YQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQ---QSLPSSH 1306
                V      T   +     S    +TT T  VT +        P++      Q L +S 
Sbjct: 11153 TSLVTSSRAVTSTTIPTLTISSDEPETT-TSLVTHSEAKMISAIPTLAVSPTVQGLVTSL 11211

Query: 1307  LTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPT--EEALKISVA 1364
             +T      SA        TV    P T  S    PG     V+P    +  E    IS+ 
Sbjct: 11212 VTSSGSETSAF----SNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLV 11267

Query: 1365  SEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAV-----PG-PG-- 1416
             + P + ++  P   +TS   H+E        ++P +  + EA++ SA+     PG PG  
Sbjct: 11268 THPAESSSTLP--RTTSRFSHSE------LDTMPSTVTSPEAESSSAISTTISPGIPGVL 11319

Query: 1417  ---------DRKTGIPTLP---------STFYSHTEKPGSFYQQVLP-HSHL-PEEALEV 1456
                      D     PT+P         +++ +H     +   +  P +SH  P+    +
Sbjct: 11320 TSLVTSSGRDISATFPTVPESPHESEATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSI 11379

Query: 1457  SVAPGPVDQTIGTPTVT-SPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTG 1515
             + +PG  + T   PT+T SP     + P ++  Q    G         S+    +  ++G
Sbjct: 11380 ATSPG-AEATSDFPTITVSP-----DVPDMVTSQVTSSG------TDTSITIPTLTLSSG 11427

Query: 1516  APTITSP--SYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYS 1573
              P  T+   +YS+    S         G+     +L +SS     D TT  PT+T T Y 
Sbjct: 11428 EPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSG---TDSTTTFPTLTETPYE 11484

Query: 1574  FGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPA-GPLGSSALGEKPITFYRQA 1632
                  I     A  +  +P    K S     T     I + GP  SSA+    I+     
Sbjct: 11485 PETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSD 11544

Query: 1633  LLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSD-SHL-PEEAL 1690
             L+ S +       S       +        +T  ++  +       T+ + SH   + A 
Sbjct: 11545 LVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAP 11604

Query: 1691  KVPPVPGPDAQK-TETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQK 1749
              +   PG D +    T ++  S+      P V   Q    +  T  A+  +  P P + +
Sbjct: 11605 SMVTSPGVDTRSGVPTTTIPPSI------PGVVTSQVTSSATDTSTAIP-TLTPSPGEPE 11657

Query: 1750  TGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSYSH 1809
             T   T +S+ +  T+       + +P S   E     S V  P    T VS  TS S+SH
Sbjct: 11658 T---TASSATHPGTQTGFTVPIRTVPSS---EPDTMASWVTHPPQTSTPVSRTTS-SFSH 11710

Query: 1810  REKPIVSYQRELPHFTEAGLKILRVPGP------ADQKTGINILPSNSYPQREHSVISYE 1863
                         P  TEA   +L    P        Q T      S + P   HS     
Sbjct: 11711 SSPDATPVMATSPR-TEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHS----- 11764

Query: 1864  QELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQEL-PDVTEEALNVF 1922
                P + E T                  A  S++   E +  F    + P V+E   ++ 
Sbjct: 11765 ---PGMPETT------------------ALLSTHPRTETSKTFPASTVFPQVSETTASLT 11803

Query: 1923  VVPGQGDRKTEIPTVPLSY-------------YSRREKPSVISQQELPDSH---LTEEAL 1966
             + PG  +  T +PT   S               S    P V ++     +H    T   +
Sbjct: 11804 IRPG-AETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMI 11862

Query: 1967  KVSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKP 2026
               S +S+   + TG+    SS+ + +    L +S            PA +  S + I   
Sbjct: 11863 PTSTLSLGLLETTGLLATSSSAETSTSTLTLTVS------------PAVSGLSSASITTD 11910

Query: 2027  KISTVIGPNDQKTPSQTAF-HSSYSQTVKPN--ILFQQQLPDRDQSK--------GILKI 2075
             K  TV   N + +PS T+     +S+TV      L   ++P   ++          IL+ 
Sbjct: 11911 KPQTVTSWNTETSPSVTSVGPPEFSRTVTGTTMTLIPSEMPTPPKTSHGEGVSPTTILRT 11970

Query: 2076  SAVPELTDVNTGK--PVSLSSSYFHREKSNIFSPQELPG 2112
             + V       TG    V+ +++ F+    ++F+P   PG
Sbjct: 11971 TMVEATNLATTGSSPTVAKTTTTFNTLAGSLFTPLTTPG 12009



 Score = 59.7 bits (143), Expect = 6e-08
 Identities = 382/1891 (20%), Positives = 647/1891 (34%), Gaps = 335/1891 (17%)

Query: 493  NLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTD----TLNQKTL---AD 545
            +L +  +  P+ S +   +S S   ++ L  SSP+ TT   HT     T +   L   +D
Sbjct: 7101 SLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSD 7160

Query: 546  THLT--EETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEALKVS 603
              LT  ++T    A+    +   +   + SS H     PS      L DS  ++    + 
Sbjct: 7161 ERLTTGKDTTNTEAVHPSTNTAASNVEIPSSGHE---SPS----SALADSETSKATSPMF 7213

Query: 604  AAPGLADQTTGMST--LTSTSYSHREKPGTFYQ--QELPESNLTEEPLEVSAAPGPVE-- 657
                  D T  +ST     TS   +E   +     +E   S  T   +E SA    V   
Sbjct: 7214 ITSTQEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIG 7273

Query: 658  QKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPH 717
              T I     TS S            LP+   T + +K       A+    T    ++P 
Sbjct: 7274 ATTEISRTEVTSSSRTSISGSAESTMLPEISTTRKIIKFPTSPILAESSEMTIKTQTSP- 7332

Query: 718  SHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQ 777
                 PG   +  F     T  +L    +T       +EI  + S       +PS L   
Sbjct: 7333 -----PGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSL--- 7384

Query: 778  DLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQ---QALLDSHLPEE 834
             + ++  P   L +SA+  P+   + LP    S+ +    LL   Q     +LD+    E
Sbjct: 7385 PVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPE 7444

Query: 835  ALKVSAVSGPADGKTGTPAVTSTS--------------SASSSLGEKPSAFYQQTLPNSH 880
                 ++S  +     T  VT+ +                SSS  E PS+     LP+S 
Sbjct: 7445 TSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSS----VLPDSE 7500

Query: 881  LTEEALKVSIVPGPGDQKTG-----------IPSAPSSFYSHREKPIIFSQQTLPDFLFP 929
             T+    +  +   GD               I S P+S  + R +    S++T       
Sbjct: 7501 TTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEAN 7560

Query: 930  EEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLT 989
                KVS  +     +T   + S  S S  E+S++   Q++    +PR  +  S++   +
Sbjct: 7561 TVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTM--SQDISIGTIPR--ISASSVLTES 7616

Query: 990  DQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSS 1049
             + T+ T T PS S                     E  L ++T   P+  +T    +Q  
Sbjct: 7617 AKMTITTQTGPSES-------------------TLESTLNLNTATTPSWVETHSIVIQGF 7657

Query: 1050 SYPQ------REKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREK 1103
             +P+      R    V +P   S   + E S   S    PA  +T    V +TF +    
Sbjct: 7658 PHPEMTTSMGRGPGGVSWP---SPPFVKETSPPSSPLSLPA--VTSPHPVSTTFLAH--- 7709

Query: 1104 PGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGT 1163
                    +P S LP  +L ++  P       GT T   TS S      S         T
Sbjct: 7710 --------IPPSPLPVTSL-LTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDT 7760

Query: 1164 HIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVL 1223
                EA   S  TG  N  T                G   Q ++     P      +  +
Sbjct: 7761 -AHTEAVHPSTNTGGTNVAT-------------TSSGYKSQSSVLADSSP---MCTTSTM 7803

Query: 1224 GPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVT 1283
            G     T TP         TE        + P        L+ S  SE     T    V 
Sbjct: 7804 GDTSVLTSTPAFLETRRIQTE----LASSLTP-------GLRESSGSEGTSSGTKMSTVL 7852

Query: 1284 STSYSQYREKPSIFYQQSLPSSHLTEEAK-NVSAVPGPADQKTVIPILPSTFYSHTEKPG 1342
            S                 +P+   TE +K +V+++PGPA Q T+ P + +   S      
Sbjct: 7853 S----------------KVPTGATTEISKEDVTSIPGPA-QSTISPDISTRTVSWFSTSP 7895

Query: 1343 VFYQQVLPHSHPTEEA-LKISVASEPVDQTT-GTPTVTSTSYSQHTEKPSIF---YQQSL 1397
            V           TE A + ++  + P+  TT GT T+ ++S +  T   S     +  S 
Sbjct: 7896 VM----------TESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSHSQ 7945

Query: 1398 PGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVS 1457
              + +    ++VS +  P   KT  P+        T  P          S LPE    +S
Sbjct: 7946 MSTLMRRGPEDVSWMSPPLLEKTR-PSFSLMSSPATTSPSPV------SSTLPE---SIS 7995

Query: 1458 VAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAP 1517
             +P PV   +        +S   +   +++K + P  + P      SV      + T   
Sbjct: 7996 SSPLPVTSLL--------TSGLAKTTDMLHKSSEPVTNSPANLSSTSVEILATSEVTTDT 8047

Query: 1518 TITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEK 1577
              T PS ++     G+        S    E+     A     + T    ITST       
Sbjct: 8048 EKTHPSSNRTVTDVGT--------SSSGHESTSFVLADSQTSKVTSPMVITSTM------ 8093

Query: 1578 PIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSP 1637
                            E   VS  +    + + I   P  S  LG +  +      L + 
Sbjct: 8094 ----------------EDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATE 8137

Query: 1638 LNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPG 1697
            ++  +  V         +TE      TS S       F Q T+S     E   ++P    
Sbjct: 8138 MSTVLSGVPTGATAEVSRTEVTSSSRTSISG------FAQLTVSPETSTETITRLP---- 8187

Query: 1698 PDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTS 1757
                   T S    + +  + P      + P+S  T   + +S  P   +     STVT 
Sbjct: 8188 --TSSIMTESAEMMIKTQTDPP-----GSTPESTHT---VDISTTPNWVETH---STVTQ 8234

Query: 1758 SFYSHTEKPNISYQQE----LPDSHLTEEALKVSNVPG-PADQKTGVSTVTST---SYSH 1809
             F SH+E   +  +       P     EE    S++   PA   T  S V+ST    +  
Sbjct: 8235 RF-SHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPA--TTSPSPVSSTLVEDFPS 8291

Query: 1810 REKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDL 1869
               P+ S        T   + I R PG +          +++     H  ++  ++  D 
Sbjct: 8292 ASLPVTSLLNPGLVITTDRMGISREPGTSS---------TSNLSSTSHERLTTLEDTVDT 8342

Query: 1870 TEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGD 1929
             ++              T +    +S   +  ++S+    E P  T      + +   G+
Sbjct: 8343 EDM---------QPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTM---GE 8390

Query: 1930 RKTEIPTVPLSYYSRRE-KPSVISQQELPDSHLTEEALKVSPVSIPAEQKTGIPIGLSSS 1988
                I T      SR + +P+      L ++  +E   ++S  +  +   + +P G ++ 
Sbjct: 8391 TSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSE---RISSATEGSTVLSEVPSGATTE 8447

Query: 1989 YSHSHKEKLKISTVHIPD------DQKTEFPAATLSSYSQIEKPKISTVI-------GPN 2035
             S +     + +++  PD      D  TE  A T  S S I      + I       G  
Sbjct: 8448 VSRTEVISSRGTSMSGPDQFTISPDISTE--AITRLSTSPIMTESAESAITIETGSPGAT 8505

Query: 2036 DQKT----PSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVNT----- 2086
             + T     S T F S    T  P     +      ++ G +   ++P + + ++     
Sbjct: 8506 SEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSVSSSL 8565

Query: 2087 GKPVSLSSSYFHREKSNI-FSPQELP-----GSHVTEDVLKVSTIPGPAGQKTVLPTALP 2140
              P   S+S+F     +I  SP  +      G   T D+L+ S+ P     +T  P  L 
Sbjct: 8566 SSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTSSEP-----ETSSPPNLS 8620

Query: 2141 SSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGTYSHGENHKLVS 2200
            S+ +          + L    +T+D  KI  +       T +  V +  Y H     +++
Sbjct: 8621 STSA----------EILATSEVTKDREKIHPSSN-----TPVVNVGTVIYKHLSPSSVLA 8665

Query: 2201 EHVQRLIDNLNSSDSSVSSNNVLLNSQADDRVVINKPES---AGFRDVG-SEEIQDAENS 2256
            + V     +  ++ S++ + +V  ++ A    ++ +P S   +G R++  S+E   A   
Sbjct: 8666 DLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATER 8725

Query: 2257 AKTLKEI----RTLLMEAENMALKRCNFPAP 2283
            + +L  +     T +   E ++L R + P P
Sbjct: 8726 SASLSGMPTGATTKVSRTEALSLGRTSTPGP 8756



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 296/1541 (19%), Positives = 513/1541 (33%), Gaps = 245/1541 (15%)

Query: 601  KVSAAPGLADQTTGMSTLTST-SYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPV--- 656
            KVSA    +      S  T T   S + KP +     +  SN    P  V  A  P+   
Sbjct: 736  KVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERVRNATSPLTHP 795

Query: 657  ----EQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKV-SAVSGPADQKTGTAT 711
                E+  G     STS    +          P G LT ++ +  S +S P+     T  
Sbjct: 796  SPSGEETAGSVLTLSTSAETTDS-----PNIHPTGTLTSESSESPSTLSLPSVSGVKTTF 850

Query: 712  VLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKP 771
              STP +H           F    +TEET     + P  +  +T +  V+++  S    P
Sbjct: 851  SSSTPSTHL----------FTSGEETEET-----SNPSVSQPETSVSRVRTTLAST-SVP 894

Query: 772  SILYPQ---------DLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFY 822
            + ++P            + SHL  E    S+ +      + LP +  S  +    +    
Sbjct: 895  TPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKI--SHLTGTATMSQTN 952

Query: 823  QQALLDSHLPEEALKVSAVSGPADG---KTGTPAVTSTSSASSSLGEKPSAFYQQTLPNS 879
            +    DS  P+      + + P      KTG P+ T+T S S++         + T P +
Sbjct: 953  RDTFNDSAAPQ------STTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPAT 1006

Query: 880  HLTEEA---------LKVSIVPGPGDQ---KTGIPSAPSSFY------SHREKPIIFSQQ 921
               E           L      GPG      T IP             SH       S +
Sbjct: 1007 SSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTTASSE 1066

Query: 922  TLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLK 981
            T  DF   +E++ +S     +    G+ T    S      S   Y     +  +PR+   
Sbjct: 1067 TSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTS 1126

Query: 982  MSAIPGLT---------------------DQKTVPTPTVP-SGSFSHREKPSIFYQQEWP 1019
             +  P +T                        + PTP V  S +FS +   +        
Sbjct: 1127 SALTPQMTATHPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVE 1186

Query: 1020 DSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPE-----ES 1074
             S      L  +T   P++  T   A+  S+    + PS       S+  LP      ES
Sbjct: 1187 TSRWNMPNLPSTTSLTPSNIPTS-GAIGKSTLVPLDTPSPATSLEASEGGLPTLSTYPES 1245

Query: 1075 LKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLP--ESHLPKEALKISVAPGLAD 1132
                +    A   +++P+      +   KPG +   T P  E+H+     +++ + G + 
Sbjct: 1246 TNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSP 1305

Query: 1133 QKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTF 1192
            + T  P  T+T         S +       T  P++       T         P  + T 
Sbjct: 1306 EMTA-PGETNTG--------STWDPTTYITTTDPKDTSSAQVST---------PHSVRTL 1347

Query: 1193 YSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSH------TEKP 1246
             +    P    +   P ++        SP L     K  T T T+   +        EK 
Sbjct: 1348 RTTENHPKT--ESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKS 1405

Query: 1247 GIFYQQVLPDNHPTEEALKISVASEPVDQTT---GTPAVTSTSYSQYREKPSIFYQQSLP 1303
              F  Q  P           ++ S  ++ T+   G P V + S       P   +  +  
Sbjct: 1406 SGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSL 1465

Query: 1304 SSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPT--EEALKI 1361
            +  +     ++S+   P     + P  P +  SH           + ++  T  ++ L I
Sbjct: 1466 TEEMASTDLDISSPSSPMSTFAIFP--PMSTPSHELSKSEADTSAIRNTDSTTLDQHLGI 1523

Query: 1362 SVASEPVDQTTG--TP-TVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDR 1418
                   D TT   TP T T TS  +H+ +       ++  +H+T+  K+ +++P     
Sbjct: 1524 RSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPA---- 1579

Query: 1419 KTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEAL--EVSVAPGPVDQTIGTPTVTSPS 1476
             +  P+  +  Y      G    +         + L  E+   P  +  T      T+ S
Sbjct: 1580 -SASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGS 1638

Query: 1477 SSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQ 1536
            SS G                    + + +A  P+G  T +P  TS + +  R  S +   
Sbjct: 1639 SSSG--------------------VTLGIAHLPIG--TSSPAETSTNMALERRSSTATVS 1676

Query: 1537 LALLGSQIPEEALRVSSAPGPA-DQTTG-IPTITS-------TSYSFGEKPIVN------ 1581
            +A  G+      L V+SAPG +  Q+ G + ++ S       T  S G  P +N      
Sbjct: 1677 MA--GTM----GLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTA 1730

Query: 1582 ----YKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSP 1637
                 + ++ +G   + +  + + S PT    +     +G S    K +T        + 
Sbjct: 1731 LSSSLEPSYAEG--SQMSTSIPLTSSPTTPDVEF----IGGSTFWTKEVT--------TV 1776

Query: 1638 LNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPG 1697
            +  ++ K SA    +     +  + ST   N GK  +      +   LP     +   P 
Sbjct: 1777 MTSDISKSSARTESSSATLMSTALGST--ENTGKEKL----RTASMDLPSPTPSMEVTPW 1830

Query: 1698 PDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKT-----GL 1752
                 +  P+ + SL                D  L     + S +   +D  +     G 
Sbjct: 1831 ISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGN 1890

Query: 1753 STVTSSFYSHTEKPNISYQ-QELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSYSHRE 1811
            ST TS  Y  TEK  +S      P++        +++ PG       +S     S    E
Sbjct: 1891 STHTSMTY--TEKSEVSSSIHPRPETSAPGAETTLTSTPG----NRAISLTLPFSSIPVE 1944

Query: 1812 KPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDLTE 1871
            + I +     P    A +    +  P    T    +  ++ P   H+V S +  +   + 
Sbjct: 1945 EVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPL--HAVSSEKVSVQTQST 2002

Query: 1872 VTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRK 1931
              + ++ V      +  +   SS+S S    AS+    E  D T    N  +     D  
Sbjct: 2003 PYVNSVAVSASPTHENSVSSGSSTS-SPYSSASL----ESLDSTISRRNA-ITSWLWDLT 2056

Query: 1932 TEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTGIPIGLSSSYSH 1991
            T +PT           PS    + L   H        S VS P+   T  P+  S++ + 
Sbjct: 2057 TSLPTTTW--------PSTSLSEALSSGH--------SGVSNPSSTTTEFPL-FSAASTS 2099

Query: 1992 SHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVI 2032
            + K++   +  H P +          SS + + +  +   I
Sbjct: 2100 AAKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASI 2140



 Score = 55.5 bits (132), Expect = 1e-06
 Identities = 395/1900 (20%), Positives = 637/1900 (33%), Gaps = 336/1900 (17%)

Query: 466  PDTVPKAPK-HLKAGDTSKGGIAKVTQSNLKS-GITTTPVDSDIGSHLSLS--LEDLSQL 521
            P +V   P+ H  +   S   +  +T S +K+ G   T +++   S  S+S  L+D+S  
Sbjct: 4757 PSSVAFTPQWHSTSSPVSMSSV--LTSSLVKTAGKVDTSLETVTSSPQSMSNTLDDISVT 4814

Query: 522  AVSSPLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGK 581
            + ++    TT    +T+           E    V+A PEP+  K  +P V +S+      
Sbjct: 4815 SAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSAYPEPS--KVTSPNVTTST------ 4866

Query: 582  PSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMST--LTSTSYSHREKPGTFYQQELPE 639
                    + D+ ++    K S       +TT   T  L  TS S +E   +     +P 
Sbjct: 4867 --------MEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSIS-QEITSSTETSTVPY 4917

Query: 640  SNLTEEPLEVSAAPGPVEQKTGIP-----TVSSTSHSHVEDLLFFYRQTLPDGHLTDQA- 693
              LT    EVS         T  P     TVS    +     L     T P   +T+ A 
Sbjct: 4918 KELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRL----STSPI--MTESAE 4971

Query: 694  LKVSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTK-----VSATP 748
            + ++  +GP    T   T    P +   + GI        S     TL       VS T 
Sbjct: 4972 ITITTQTGPHGA-TSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTS 5030

Query: 749  GPADQKTEIPAVQSSSYSQREKPSIL---YPQDLADSHLPEEGLKVSAVAGPAD-QKTGL 804
             P+  KT  P+   SS +    PS++    P+D   S  P   L  S +    D  +T L
Sbjct: 5031 PPSVDKTSSPSSFLSSPAMTT-PSLISSTLPEDKLSS--PMTSLLTSGLVKITDILRTRL 5087

Query: 805  PTVPSSA---YSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSAS 861
              V SS     S  +K+L   +    DS   +E    S  +   + K       S S A 
Sbjct: 5088 EPVTSSLPNFSSTSDKILATSK----DSKDTKEIFP-SINTEETNVKANNSGHESHSPAL 5142

Query: 862  SSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQ 921
            +   E P A  Q  +  + + + A   S+      + T I   P+ F + R +    SQ+
Sbjct: 5143 AD-SETPKATTQMVITTT-VGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQE 5200

Query: 922  TLPDFLFPEEAL----KVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDS---D 974
            +     FP +      KV   ++     TG  + S  S    +KS+V      PD+   +
Sbjct: 5201 SS----FPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTV-----PPDTFTGE 5251

Query: 975  LPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKP---SIFYQQEWPDSYAT------E 1025
            +PR  +  S+I   + + T+ T   P  S SH   P   S    Q    S  T      E
Sbjct: 5252 IPR--VFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSE 5309

Query: 1026 KALKVSTGPGPADQKTEIPAVQSSSYPQ-REKPSVLYPQVLSDSH---LPEESLKVSAFP 1081
                +  GPG     T  P  ++SS       P++  P  +S +    +P   L V+A P
Sbjct: 5310 VTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALP 5369

Query: 1082 -----------GPADQMTDTPAVPSTFYSQREKPGIF----------------------- 1107
                       G     + T + P+      E+P  +                       
Sbjct: 5370 TSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGT 5429

Query: 1108 -------YQQTLPESHLPKEALKISVAPGLADQK--TGTPTVTSTSYSQHREKPSIFHQQ 1158
                       L +S   K    +S    L D    T TP ++ T+  Q     S+    
Sbjct: 5430 SGSGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLS--- 5486

Query: 1159 ALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQK 1218
              P       ++K S+ T      +++P    T  S+ E      + ++     P  A  
Sbjct: 5487 --PRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSS--RTSISDLDRPTIAPD 5542

Query: 1219 VSPVL------GPADQKTGTPTPTSASYSHTEKPGIFYQQVLP----------DNHPT-E 1261
            +S  +       P   K+   T T+     T  PG   Q +LP            H T  
Sbjct: 5543 ISTGMITRLFTSPIMTKSAEMTVTT----QTTTPGATSQGILPWDTSTTLFQGGTHSTVS 5598

Query: 1262 EALKISVASEPVDQTTG------TPAVTSTSYSQYREKPSIFYQ--------QSLPSSHL 1307
            +    S  +    +T G      TP V  TS       PS+           +S+PSS L
Sbjct: 5599 QGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPL 5658

Query: 1308 TEEA---------KNVSAVPGPADQKTVIPILPS------TFYSHTEKPGVFYQQVLPHS 1352
               A          NV     P    +  P L S      T Y  T      +  +  ++
Sbjct: 5659 PVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHTNT 5718

Query: 1353 HPTEEALKIS----VASEPVDQTTGTPT--------VTSTSYSQHTEKPSIFYQQS---- 1396
                    IS     +S P D  T   T        +  TS S  T  P+ F  +     
Sbjct: 5719 AVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDTSVS--TSTPAFFETRIQTES 5776

Query: 1397 ----LPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEE 1452
                +PG   T  ++ ++ V       + +PT  +T  S TE   S    +    H    
Sbjct: 5777 TSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTISGPDH---- 5832

Query: 1453 ALEVSVAPGPVDQTIGTPTVTSPSS---SFGEKPIVIYKQAFPEGHLPEESLKVSVAPGP 1509
                      +   I T T+T  S+     G   + I  Q  P G + + +L +  +   
Sbjct: 5833 --------SKMSPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTA 5884

Query: 1510 VGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITS 1569
              + T +P      +S+         +     S    E     S+P P      +P ITS
Sbjct: 5885 SWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVP------LPAITS 5938

Query: 1570 TSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFY 1629
             S  +      +   A P   L     + +I    T  +    + P  SS  GE   +  
Sbjct: 5939 HSSLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTS-- 5996

Query: 1630 RQALLDSPLNKEVVKVSAAPGPADQKTETLPVHS--TSYSNRGKPVIFYQQTLSDSHLPE 1687
                 ++  N E +  S      +  T T  +H   +S S   +P       ++ S + E
Sbjct: 5997 -----EASTNTETIHFSENTAETNMGT-TNSMHKLHSSVSIHSQPSGHTPPKVTGS-MME 6049

Query: 1688 EALKVPPVPG-PDAQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPA 1746
            +A+     PG P+ +  +  S S      +E        +  +S     ++ +       
Sbjct: 6050 DAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSL------- 6102

Query: 1747 DQKTGLSTVTSSFYSHTEKPNISYQQELPD-------SHLTEEALKVSNVPGPADQKTGV 1799
            D  T +S    ++Y  T  P  +   + PD       SH     L +S     A Q TG 
Sbjct: 6103 DAATEVSRAEVTYYDPTFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQ-TGP 6161

Query: 1800 STVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGI-------NILPSNSY 1852
            S VTS      +   ++        T AG    R     D +T         ++L ++ +
Sbjct: 6162 SGVTSLGQLTLDTSTIA--------TSAGTPSARTQDFVDSETTSVMNNDLNDVLKTSPF 6213

Query: 1853 PQREHSVISYEQEL-----PDLTEVTLK---------AIGVPGP-----ADQKTGIQIAS 1893
               E + +S +  L     P     TL+            VP P      D  T ++  +
Sbjct: 6214 SAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVT 6273

Query: 1894 SSSYSNR-----EKASIFHQQELPDVTEEALNV----------FVVPGQGDRKTEIPTVP 1938
             S  + R      +A+       P +     NV          F V    D       V 
Sbjct: 6274 RSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDSDPYKATSAVV 6333

Query: 1939 LSYYSRREKPSVISQQELPDSHL--TEEALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEK 1996
            ++  S     S++S      S +   E     S +    E  T   IG SS  S    + 
Sbjct: 6334 ITSTS---GDSIVSTSMPRSSAMKKIESETTFSLIFRLRETSTSQKIGSSSDTSTVFDKA 6390

Query: 1997 LKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQT-VKP 2055
               +T  +    +TE  +++ +S    EKP +S      D  T S T   +    T  + 
Sbjct: 6391 FTAATTEV---SRTELTSSSRTSIQGTEKPTMSP-----DTSTRSVTMLSTFAGLTKSEE 6442

Query: 2056 NILFQQQLPDRDQSKGILKISAVPELTDVNTGKPVSLSSSYFHREKSNI----------F 2105
              +  Q  P R  S+G L       +T    G   +++  +   + S +           
Sbjct: 6443 RTIATQTGPHRATSQGTLTWDT--SITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYISGT 6500

Query: 2106 SPQELPGSHVTEDVLKVSTIPGPAGQKTVLPTALPSSFSH 2145
            SP  +  +  +  +L +  I  P+   T LP + PSS  H
Sbjct: 6501 SPPSVEKTSSSSSLLSLPAITSPSPVPTTLPESRPSSPVH 6540



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 439/2193 (20%), Positives = 754/2193 (34%), Gaps = 323/2193 (14%)

Query: 481  TSKGGIAKVTQSN---LKSGITTTPVDSDIGSHLSLSLEDLSQLAV-------------S 524
            TS   ++ +T  +    ++ ++TT + S + ++  ++ E  +  +V             +
Sbjct: 3374 TSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQT 3433

Query: 525  SPLETTTGQHTDTLNQKTLADTHLTEETLK-------VTAIPEPADQKTATPTVLSSS-- 575
            S  + T G   D  N   +  T  T   +        +T++  P+  KT++ + ++S   
Sbjct: 3434 SGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSI 3493

Query: 576  --HSHRGKPSIFYQQGLPDS-HL--TEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPG 630
               + R   S       P + HL  T    +VS        T G+ST T T+        
Sbjct: 3494 GLETLRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGIST-TITTMGTNSIST 3552

Query: 631  TFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHL- 689
            T    E+  S +   P             T   T +S S + V D+    +     G + 
Sbjct: 3553 TTPNPEVGMSTMDSTPATERRTTSTEHPSTWSSTAASDSWT-VTDMTSNLKVARSPGTIS 3611

Query: 690  TDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPG 749
            T       A S   D        +STPH      G       +D+   +   +    T  
Sbjct: 3612 TMHTTSFLASSTELDS-------MSTPHGRITVIGTSLVTPSSDASAVKTETSTSERTLS 3664

Query: 750  PADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLPE----EGLKVSAVAGPADQKTGLP 805
            P+D     P    S++S+ ++ SI  P  L+ S  P     E + VS V+         P
Sbjct: 3665 PSDTTASTPI---STFSRVQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDP 3721

Query: 806  TVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLG 865
              P S +       +F   + LD          +A +    G T    +T  +  S +  
Sbjct: 3722 NTPLSTF-------LFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLETMISPATS 3774

Query: 866  EKPSAFYQQTLPNSHLTEEALKVSIV-----PGPGDQK-----TGIPSAPSSFYSHREKP 915
            + P +    T   S +T  A+  S       P P  +K     T +P+  S+      + 
Sbjct: 3775 QLPFSIGHIT---SAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRS 3831

Query: 916  IIFSQQTLPDFL-FPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKS--SVFYQQELPD 972
               +   +P     P+   +    + L  +   T    S+S +  EKS  S  +  E+ +
Sbjct: 3832 AATTLDVIPHTAKTPDATFQRQGQTALTTEARAT----SDSWNEKEKSTPSAPWITEMMN 3887

Query: 973  S---DLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEK-AL 1028
            S   D  +E    S++    +   +   +  + S S +  P   Y++  P    T+K A+
Sbjct: 3888 SVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSP---YERIAPSESTTDKEAI 3944

Query: 1029 KVSTGP-GPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQM 1087
              ST         T       S+ P     S L   V++ S   +  + +S    P  + 
Sbjct: 3945 HPSTNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWP--ES 4002

Query: 1088 TDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQ 1147
            T     P++F +   +    Y  T   +        I  +PG      G  T  ++S   
Sbjct: 4003 TRARTEPNSFLTIELRDVSPYMDTSSTTQT-----SIISSPGSTAITKGPRTEITSS--- 4054

Query: 1148 HREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPG-IFYQQT 1206
             +   S F  Q++  +  P EA               I R LS F +  E  G I   QT
Sbjct: 4055 -KRISSSFLAQSMRSSDSPSEA---------------ITR-LSNFPAMTESGGMILAMQT 4097

Query: 1207 LPGSHIPEEAQKVSPVLGPADQK--TGTPTPTSASYSHTEKPGIFY---QQVLPDNHPTE 1261
             P    P      +P L  +     TGTP  T+  ++++EK  +F    +     + P+ 
Sbjct: 4098 SP----PGATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSV 4153

Query: 1262 EALKISVASEPVDQTTGTPAV--TSTSYSQYREKP--SIFYQQSLPSSHLTEEAKNVSAV 1317
            E    S +  P+  TT    +  TS  +S     P  S+F  ++      T+ ++ +S  
Sbjct: 4154 EETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSR-ISLE 4212

Query: 1318 PG---PADQKTVIPILPSTFYSHTEKPGVFYQ---QVLPHSHPTEEALKISVASEPVDQT 1371
            PG   P +  +      ST+ +  +   + +     V      + E   I   ++P   T
Sbjct: 4213 PGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKAT 4272

Query: 1372 TGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAV-PGPGDRKT----GIPTLP 1426
              +P VTS      T   S+F      GS  T E + VS+V  G  +R T       T  
Sbjct: 4273 --SPLVTSHIMGDITSSTSVF------GSSETTEIETVSSVNQGLQERSTSQVASSATET 4324

Query: 1427 STFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVI 1486
            ST  +H    G     V            +S    P      T T T  S++     I+ 
Sbjct: 4325 STVITHVSS-GDATTHVTKTQATFSSGTSIS---SPHQFITSTNTFTDVSTNPSTSLIM- 4379

Query: 1487 YKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPE 1546
                          + ++   GP G  T  P +   S   +  ++     LA+    +  
Sbjct: 4380 ---------TESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTET----PLAVTPDFMQS 4426

Query: 1547 EALRVSSAPGPADQT-TGIPTITSTSYSFGEKP-----IVNYKQAFPDGHLPEEALKVSI 1600
            E   + S  GP D + T  P++  TSY     P     I          H        S+
Sbjct: 4427 EKTTLIS-KGPKDVSWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSV 4485

Query: 1601 VSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAA-------PGPAD 1653
            ++    K TD+    L +S    +P+T   Q  L++P N+ +  ++A        P    
Sbjct: 4486 LTSGLVKTTDM----LNTSM---EPVTNSPQN-LNNPSNEILATLAATTDIETIHPSINK 4537

Query: 1654 QKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPE----EALKVPPVPGPDAQKTETPSVS 1709
              T      S    +   PV     T +   +P     +AL    +PG +    E    S
Sbjct: 4538 AVTNMGTASSAHVLHSTLPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTS 4597

Query: 1710 SSLYSYREKPIVFYQQALPDSELTQEALKVSA----------------VPQPADQK--TG 1751
            S     +E   +    +  +S +    + V A                +P PA       
Sbjct: 4598 SLTAGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPD 4657

Query: 1752 LSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKT-----GVSTVTSTS 1806
            + +V SS  S++    IS          T  +   S +P   D  T     G  +V +  
Sbjct: 4658 IFSVASSRLSNSPPMTISTHMTTTQ---TGSSGATSKIPLALDTSTLETSAGTPSVVTEG 4714

Query: 1807 YSHRE------KPIVSYQRELPHFTEAGLKILRVPGPADQ-KTGINILPSN-SYPQREHS 1858
            ++H +        +    +  P F +          P+ Q    +  LPS+ ++  + HS
Sbjct: 4715 FAHSKITTAMNNDVKDVSQTNPPFQD------EASSPSSQAPVLVTTLPSSVAFTPQWHS 4768

Query: 1859 VISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDV--TE 1916
              S       LT   +K     G  D       +S  S SN             D+  T 
Sbjct: 4769 TSSPVSMSSVLTSSLVK---TAGKVDTSLETVTSSPQSMSNTLDDISVTSAATTDIETTH 4825

Query: 1917 EALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPV--SIP 1974
             ++N  V        T + T   ++ S     +     ++   ++T   ++ + +  SIP
Sbjct: 4826 PSINTVV--------TNVGTTGSAFESHSTVSAYPEPSKVTSPNVTTSTMEDTTISRSIP 4877

Query: 1975 AEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGP 2034
               KT       +  + S   KL+ +++       TE      S+    E    +T +  
Sbjct: 4878 KSSKT---TRTETETTSSLTPKLRETSISQEITSSTE-----TSTVPYKELTGATTEVSR 4929

Query: 2035 NDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVNTGKPVSLSS 2094
             D  + S T+F      TV  +I    +   R  +  I+  SA   +T   TG   + S 
Sbjct: 4930 TDVTSSSSTSFPGPDQSTVSLDI--STETNTRLSTSPIMTESAEITIT-TQTGPHGATSQ 4986

Query: 2095 SYFHREKSNIFSPQELPGSHVTE--DVLKVSTIPGPAGQ-------KTVLPTALPSSF-- 2143
              F  + SN  +PQ    S +T     L V+T+     Q        +V  T+ PSSF  
Sbjct: 4987 DTFTMDPSNT-TPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLS 5045

Query: 2144 SHREKPDIFYQKDLPDRHLTEDALK-ISSALGQADQI--TGLQTVPSGTYSHGENHKLV- 2199
            S            LP+  L+      ++S L +   I  T L+ V S   +       + 
Sbjct: 5046 SPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVTSSLPNFSSTSDKIL 5105

Query: 2200 -----SEHVQRLIDNLNSSDSSVSSNNVLLNSQADDRVVINKPESAGFRDVGSEEIQDAE 2254
                 S+  + +  ++N+ +++V +NN    S +        P++     + +     A 
Sbjct: 5106 ATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKATTQMVITTTVGDPAP 5165

Query: 2255 NSAKTLKEIRTLLMEAENMALKRCNFPAPLARFRDIS-------DISFIQSK-KVVCFKE 2306
            +++  +        E  N+  +   F  P  R    S       D SF+ SK       E
Sbjct: 5166 STSMPVHG----SSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITE 5221

Query: 2307 PSSTGVSNGDLLHR----------QPFTEESPSSRCIQKDIGTQTNLKCRRGIENWEFIS 2356
             SSTGV++   +              FT E P  R     I T++           E   
Sbjct: 5222 VSSTGVNSSSKISTPDHDKSTVPPDTFTGEIP--RVFTSSIKTKSA----------EMTI 5269

Query: 2357 STTVRSPLQEAESKVSMALEETLRQYQAAKSVMRSEPEGCSGTI-----GNKIIIPMMTV 2411
            +T    P   + S + +    TL Q     +V +  P     T+     GN   +  MT 
Sbjct: 5270 TTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYSEVTTLMGMGPGN---VSWMTT 5326

Query: 2412 IKSDSSSDASDGNGSCSWDSNLPESLESVSDVLLNFFPYVSPKTSI----TD---SREEE 2464
               + +S  S    S +  S  P S  S   +  +  P  +  TS+    TD   +   E
Sbjct: 5327 PPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPE 5386

Query: 2465 GVSESEDGGGSSVDSLAAHVKNLLQCESSLNHA 2497
             V+ S     S      A  K+    E++++H+
Sbjct: 5387 SVTSSPPNLSSITHERPATYKDTAHTEAAMHHS 5419



 Score = 52.8 bits (125), Expect = 7e-06
 Identities = 458/2327 (19%), Positives = 799/2327 (34%), Gaps = 411/2327 (17%)

Query: 164  DSSQTLDTSQTRFNVRTEDTEVTDFPSLE-EGILTQSENQVKEPNRDLFCSPLLVIQDSF 222
            +S+ TLDTS T   V T  T     P  E   ++++    V  P      S L V + S 
Sbjct: 7338 ESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRP------SSLPVEETSP 7391

Query: 223  ASPDLPLLTCLTQDQEFAP-DSLFHQSELSFAPL--------RGIPDKSEDTEWSSRPSE 273
             S  L L   ++     +   +  H S  S   L          + D S + E SS PS 
Sbjct: 7392 PSSQLSLSAMISPSPVSSTLPASSHSSSASVTSLLTPGQVKTTEVLDASAEPETSSPPSL 7451

Query: 274  VSEAL-FQATAEVASDLASSR-FSVSQHPLIGSTAVGSQCPFLPSEQGNNEETISSVDEL 331
             S ++   AT+EV +D      FS +    +G+++ G + P          +  S++  +
Sbjct: 7452 SSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSETTKATSAMGTI 7511

Query: 332  KIPKDCDRYDDLCSYMSWKTRKDTQWPENNLADK-------DQVSVATSFDITDENIATK 384
             I  D      L   +S  TRK    P ++L  +       ++ S+AT  +     ++T 
Sbjct: 7512 SIMGDTS-VSTLTPALS-NTRKIQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTG 7569

Query: 385  RSDHFDAARSYGQYWTQEDSSKQAETYLTKGLQGKVESDVITLDGLNENAVVCSERVAEL 444
                           T E S  +A ++    + G  +S +     +     + +  V   
Sbjct: 7570 A--------------TTEVSRTEAISFSRTSMSGPEQSTMSQDISIGTIPRISASSVLTE 7615

Query: 445  QRKPTRESEYHSSDLRM---LRMSPDTVPK-------------APKHLKAGDTSKGGIA- 487
              K T  ++   S+  +   L ++  T P               P+   +     GG++ 
Sbjct: 7616 SAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFPHPEMTTSMGRGPGGVSW 7675

Query: 488  ------KVTQS-----NLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETT----TG 532
                  K T       +L +  +  PV +   +H+  S   ++ L  S P  TT    T 
Sbjct: 7676 PSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTS 7735

Query: 533  QHTDTLNQKTLADT-HLTEETLKVTAIPEPADQKTAT--PTVLSSSHSHRGKPSIFYQQG 589
                T +  +L+ T H    T K TA  E     T T    V ++S  ++ + S+     
Sbjct: 7736 TEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSSV----- 7790

Query: 590  LPDSHLTEEALKVSAAPGLADQTTG-MSTLTSTSYSHREKPGTFYQQELPESNLTEEPLE 648
            L DS           +P     T G  S LTST                 E+   +  L 
Sbjct: 7791 LADS-----------SPMCTTSTMGDTSVLTSTP-------------AFLETRRIQTELA 7826

Query: 649  VSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALK-VSAVSGPA---- 703
             S  PG  E      T S T  S V          +P G  T+ + + V+++ GPA    
Sbjct: 7827 SSLTPGLRESSGSEGTSSGTKMSTV-------LSKVPTGATTEISKEDVTSIPGPAQSTI 7879

Query: 704  --DQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQ 761
              D  T T +  ST     E   I      +    T +  + +  +   +   T     Q
Sbjct: 7880 SPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQ 7939

Query: 762  SSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVF 821
              S+SQ        P+D            VS ++ P  +KT                   
Sbjct: 7940 GFSHSQMSTLMRRGPED------------VSWMSPPLLEKTR------------------ 7969

Query: 822  YQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLP-NSH 880
                                  P+     +PA TS S  SS+L   P +     LP  S 
Sbjct: 7970 ----------------------PSFSLMSSPATTSPSPVSSTL---PESISSSPLPVTSL 8004

Query: 881  LTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLP-DFLFPEEALKVSAVS 939
            LT    K + +     +   + ++P++  S   + +  S+ T   +   P     V+ V 
Sbjct: 8005 LTSGLAKTTDMLHKSSEP--VTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVG 8062

Query: 940  VLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTV 999
              ++    T  V ++S +    S +     + D+ +       ++ PG  +   + T   
Sbjct: 8063 TSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVS------TSTPGFFETSRIQTEPT 8116

Query: 1000 PSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSV 1059
             S +   R+  S         S ATE +  +S  P  A  +     V SSS     + S+
Sbjct: 8117 SSLTLGLRKTSS-----SEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSS-----RTSI 8166

Query: 1060 LYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPK 1119
                 L+ S  PE S +       +  MT++  +     +Q + PG     + PES    
Sbjct: 8167 SGFAQLTVS--PETSTETITRLPTSSIMTESAEM--MIKTQTDPPG-----STPES---T 8214

Query: 1120 EALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQA----LPGTHIPEEAQKVSAV 1175
              + IS  P   +  +     T T    H E  ++  +       P     EE    S++
Sbjct: 8215 HTVDISTTPNWVETHS-----TVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSL 8269

Query: 1176 TGPGNQKTWIPRVLSTFYSQREKPGIFYQQTL-PGSHIPEEAQKVSPVLGPADQKTGTPT 1234
                   +  P V ST         +     L PG  I  +   +S    P    T   +
Sbjct: 8270 LSLPATTSPSP-VSSTLVEDFPSASLPVTSLLNPGLVITTDRMGISRE--PGTSSTSNLS 8326

Query: 1235 PTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQT----TGTPAVTS---TSY 1287
             TS     T +  +  + + P  H     ++ S++      +    + TP  TS   T+Y
Sbjct: 8327 STSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTY 8386

Query: 1288 SQYREKPSI----FYQQSL----PSSHLTEEAKNVSA---VPGPADQKTVIPILPSTFYS 1336
            +      SI    F++ S     P+S LT   +  S+   +    +  TV+  +PS   +
Sbjct: 8387 TMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATT 8446

Query: 1337 HTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQ---HTEKPSIFY 1393
               +  V   +    S P +  +   +++E + + + +P +T ++ S     T  P    
Sbjct: 8447 EVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATS 8506

Query: 1394 QQSLP-GSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLP-- 1450
            + +L   +  T       +   PG   + + TL S        PG      +P   LP  
Sbjct: 8507 EGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMS------RTPGD-----VPWPSLPSV 8555

Query: 1451 EEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHL-------PEESLKV 1503
            EEA  VS        ++ +P +TS +S F   P  I     P   L         + L+ 
Sbjct: 8556 EEASSVS-------SSLSSPAMTS-TSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRT 8607

Query: 1504 SVAP----GPVGQTTGAPTITSPSYSQHRAK--SGSFYQLALLGSQIPEEALRVSSAPGP 1557
            S  P     P   +T A  + +   ++ R K    S   +  +G+ I +    +S +   
Sbjct: 8608 SSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTVIYK---HLSPSSVL 8664

Query: 1558 ADQTTGIPTI-TSTSYSFGEKPIVNYKQAFPDGHL--PEEALKVSI--------VSGPTE 1606
            AD  T  PT   +T+ + G   +     AFP+  +  P  +L   +         S  TE
Sbjct: 8665 ADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATE 8724

Query: 1607 KKTDIPAGPLGSS---------ALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTE 1657
            +   +   P G++         +LG        Q+ +   ++ E +   + P       E
Sbjct: 8725 RSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAE 8784

Query: 1658 TLPVHSTSYSNRGKPVIFYQQTLSDS-----------HLPEEALKVPPVPGPD------- 1699
                  T +S       F   T S +             P   +  P   GP+       
Sbjct: 8785 MTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSR 8844

Query: 1700 --AQKTETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTS 1757
               +KT  PS   SL S    P   Y  + P        L+V+++  P   KT     TS
Sbjct: 8845 PSVEKTSPPSSLVSL-SAVTSPSPLY--STPSESSHSSPLRVTSLFTPVMMKTTDMLDTS 8901

Query: 1758 SFYSHTEKP--NISYQQELPDSHLTEEALKV---------------------SNVPG-PA 1793
                 T  P  NI+  + L  S  T E   +                     S+ PG P 
Sbjct: 8902 LEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPE 8961

Query: 1794 DQKTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYP 1853
              K     VTS++        +    E+          L  P P +  T   I  +    
Sbjct: 8962 PSKVTSPVVTSSTIKDIVSTTIPASSEITRIEMESTSTL-TPTPRETSTSQEIHSATKPS 9020

Query: 1854 QREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPD 1913
               +  ++       +T+V   + G P P DQ T  Q  S+   +    + I  +     
Sbjct: 9021 TVPYKALTSATIEDSMTQVMSSSRG-PSP-DQSTMSQDISTEVITRLSTSPIKTESTEMT 9078

Query: 1914 VTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSI 1973
            +T +  +    PG   R T       ++ S        + Q    S +T   +  +P  +
Sbjct: 9079 ITTQTGS----PGATSRGTLTLDTSTTFMSGTHS---TASQGFSHSQMT-ALMSRTPGDV 9130

Query: 1974 PAEQKTGIPIGLSSSYSHSHKEKLKISTVH--IPDD-QKTEFPAATLSSYSQIEKPKIST 2030
            P      +    S+S+S S       S V   +PD    +  P  +L +   +   K + 
Sbjct: 9131 PWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLV---KTTE 9187

Query: 2031 VIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVNTGKPV 2090
            ++G + +    +T+   + S T    +   +   D ++           E+T+V      
Sbjct: 9188 LLGTSSE---PETSSPPNLSSTSAEILAITEVTTDTEKL----------EMTNV------ 9228

Query: 2091 SLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPAGQKTVLPTALPSSFSHR--EK 2148
             ++S Y H       SP  +    VT        I  P G   VL +    S + R   K
Sbjct: 9229 -VTSGYTHE------SPSSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTK 9281

Query: 2149 PDIFYQKDLPDRHLTEDALKISSALGQADQITGLQTVPSGTYSHGENHKLVSE---HVQR 2205
              +     L +  ++E+    SSA    ++ T L +VP+G  +     + +S     +  
Sbjct: 9282 SKLSLTPGLMETSISEET---SSA---TEKSTVLSSVPTGATTEVSRTEAISSSRTSIPG 9335

Query: 2206 LIDNLNSSDSSVSS----NNVLLNSQADDRVVINKPESAGFRDVGSEEIQDAE------- 2254
               +  SSD+S+ +    +  L   ++ D  +  K   +G    G+  +  +        
Sbjct: 9336 PAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLDSSSTASWPGT 9395

Query: 2255 NSAKTLKEIRTLLMEAENMALKRCNFPAPLARFRDISDISFIQSKKV 2301
            +SA T +  ++++    +   +  ++P+PL+  ++    S + S  V
Sbjct: 9396 HSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSV 9442



 Score = 51.2 bits (121), Expect = 2e-05
 Identities = 469/2319 (20%), Positives = 795/2319 (34%), Gaps = 377/2319 (16%)

Query: 351  TRKDTQWPENNLADKDQVSVATSFDITDEN-IATKRSDHFDAARSYGQY-WTQEDSSKQA 408
            T K T  P+ +      +S       ++E  IAT+   H   A S G   W    ++ QA
Sbjct: 6414 TEKPTMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPH--RATSQGTLTWDTSITTSQA 6471

Query: 409  ETYLTKGLQGKVESDVITLDGLNENAVVCSERVAEL---QRKPTRESEYHSSDLRML--- 462
             T+      G  + D+ TL          + RV E       P+ E    SS L  L   
Sbjct: 6472 GTHSAM-THGFSQLDLSTL----------TSRVPEYISGTSPPSVEKTSSSSSLLSLPAI 6520

Query: 463  -------RMSPDTVPKAPKHLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSH----L 511
                      P++ P +P HL +  TS  G+ K T  ++ + + + P +    SH     
Sbjct: 6521 TSPSPVPTTLPESRPSSPVHLTSLPTS--GLVKTT--DMLASVASLPPNLGSTSHKIPTT 6576

Query: 512  SLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTV 571
            S  ++D  ++  S+ +   T   T T  +++ +      E  KVT+            T+
Sbjct: 6577 SEDIKDTEKMYPSTNI-AVTNVGTTTSEKESYSSVPAYSEPPKVTS--PMVTSFNIRDTI 6633

Query: 572  LSSSHSHRGKPSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGT 631
            +S+S             G  +    E     S A GL   +T    + ST     EK   
Sbjct: 6634 VSTS-----------MPGSSEITRIEMESTFSLAHGLKGTSTSQDPIVST-----EKSAV 6677

Query: 632  FYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPD--GHL 689
             ++       LT    E S       ++T IP    ++ S   D+      +LP   G  
Sbjct: 6678 LHK-------LTTGATETSRTEVASSRRTSIPGPDHSTES--PDISTEVIPSLPISLGIT 6728

Query: 690  TDQALKVSAVSGPADQKT--GTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTK---- 743
                + +   +GP    T  GT T+ +   S R        QEF  S  T   + K    
Sbjct: 6729 ESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMTT-VMNKDPEI 6787

Query: 744  VSATPGPADQKTEIPAVQSSSYSQREKP-SILYPQDLADSHLPEEGLKVSAVAGPADQKT 802
            +S T  P+ +KT   +    S +    P S   P+ +  +  P   L   ++    D   
Sbjct: 6788 LSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDT-- 6845

Query: 803  GLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASS 862
             L T P    S    L     + L      E+   + A+       + + A T+  + SS
Sbjct: 6846 -LGTSPEPTTSSPPNLSSTSHEILTTD---EDTTAIEAMH-----PSTSTAATNVETTSS 6896

Query: 863  SLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSH--REKPIIFSQ 920
              G + S      L +S  T+    +      G        + SS  +   RE     + 
Sbjct: 6897 GHGSQSSV-----LADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTP 6951

Query: 921  QTLPDFLFPEEALKVSAVSVLAAQKTGTPT-VSSNSHSHSEKSSVFYQQE---LPDSDLP 976
                  +    +       VL+   TGT   VS    + S ++S+    +   LP+    
Sbjct: 6952 GLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEIST- 7010

Query: 977  RESLKMSAIPGLTD--QKTVPTPTVPSGSFSH------------REKPSIFYQQEWPDSY 1022
            R   ++ A P +T+  + T+PT T PSGS S             + K      Q +P S 
Sbjct: 7011 RTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHS- 7069

Query: 1023 ATEKALKVSTGPGPADQKTEIPAVQSS-------SYPQREKP---SVLYPQVLSDSHLPE 1072
              E    +S GPG    ++  P++++        S P    P   S   P  +S S LP 
Sbjct: 7070 --EMTTLMSRGPGDMSWQSS-PSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPV 7126

Query: 1073 ESLKVSAFPGPADQMTDTPAV-----PSTFYSQRE-----KPGIFYQQTLPESHLPKEAL 1122
             SL  S+     D +  +P +     P   ++  E     K     +   P ++     +
Sbjct: 7127 TSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAASNV 7186

Query: 1123 KI------SVAPGLADQKT--------------------GTPTVTSTSYSQHREKPSIFH 1156
            +I      S +  LAD +T                     TP    TS  Q     S+  
Sbjct: 7187 EIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSP 7246

Query: 1157 QQALPGTHI-PEEAQKVSAVTGPGN--QKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIP 1213
            +    G+ +    A + SAV    +    T I R   T  S+    G      LP     
Sbjct: 7247 KLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTT 7306

Query: 1214 EEAQK--VSPVLGPADQ---KTGTPTPTSASYS------HTEKPGIFYQQVLPDNHPTEE 1262
             +  K   SP+L  + +   KT T  P S S S       T    +     +    P  E
Sbjct: 7307 RKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSE 7366

Query: 1263 ALKI---------SVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKN 1313
               +           +S PV++T  +P  +  S S       +    +LP+S  +  A +
Sbjct: 7367 ITTLVSRGAGDVPRPSSLPVEET--SPPSSQLSLSAMISPSPV--SSTLPASSHSSSA-S 7421

Query: 1314 VSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQ---QVLPHSHPTEEALKISVASEPVDQ 1370
            V+++  P   KT   +L ++    T  P        ++L  S  T +  KI     P   
Sbjct: 7422 VTSLLTPGQVKTT-EVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKI----HPFSN 7476

Query: 1371 TTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDR--KTGIPTLPST 1428
            T  T   TS+S     E PS      LP S  T+    +  +   GD    T  P L +T
Sbjct: 7477 TAVTKVGTSSS---GHESPS----SVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNT 7529

Query: 1429 FYSHTEKPGSFYQQVLPHSHLPEEALEV-------SVAPGPVDQTIGTPTVTSPSSSFGE 1481
                +E   S   ++   S   E +L          V+ G   +   T  ++   +S   
Sbjct: 7530 RKIQSEPASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSG 7589

Query: 1482 KPIVIYKQAFPEGHLPE--------ESLKVSVA--PGP----VGQTTGAPTITSPSYSQH 1527
                   Q    G +P         ES K+++    GP    +  T    T T+PS+ + 
Sbjct: 7590 PEQSTMSQDISIGTIPRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVE- 7648

Query: 1528 RAKSGSFYQLALLGSQIPEEALRVSSAPG--------------PADQTTGIPTITSTSYS 1573
                   + + + G   PE    +   PG              P      +P +TS    
Sbjct: 7649 ------THSIVIQGFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTS---- 7698

Query: 1574 FGEKPIVNYKQAFPDGHLPEEALKVS--IVSGPTEKKTDI---PAGPLGSSALGEKPITF 1628
                P+     A    H+P   L V+  + SGP    TDI      P  SS+      + 
Sbjct: 7699 --PHPVSTTFLA----HIPPSPLPVTSLLTSGPA-TTTDILGTSTEPGTSSSSSLSTTSH 7751

Query: 1629 YRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEE 1688
             R        + E V  S   G  +  T      S+ Y ++   +       + S + + 
Sbjct: 7752 ERLTTYKDTAHTEAVHPSTNTGGTNVATT-----SSGYKSQSSVLADSSPMCTTSTMGDT 7806

Query: 1689 ALKVPPVPGPDAQKTETPSVSSSLYSYREK----------PIVFYQQALPDSELTQEALK 1738
            ++        + ++ +T   SS     RE            +      +P    T+ + +
Sbjct: 7807 SVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATTEISKE 7866

Query: 1739 -VSAVPQPADQ--KTGLSTVTSSFYS----HTEKPNISYQQELPDSHLTEEALKVSNVPG 1791
             V+++P PA       +ST T S++S     TE   I+          T +     +   
Sbjct: 7867 DVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSS 7926

Query: 1792 PADQKTGVSTVTSTSYSHRE---------KPIVSYQRELPHFTEAGLKILRVPGPADQKT 1842
                    ST+ S  +SH +         + +      L   T     ++  P       
Sbjct: 7927 TTSLTMTHSTI-SQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSP 7985

Query: 1843 GINILPS--NSYPQREHSVISYEQELPDLTEVTLKAIG--VPGPAD-QKTGIQI-ASSSS 1896
              + LP   +S P    S+++    L   T++  K+       PA+   T ++I A+S  
Sbjct: 7986 VSSTLPESISSSPLPVTSLLT--SGLAKTTDMLHKSSEPVTNSPANLSSTSVEILATSEV 8043

Query: 1897 YSNREKASIFHQQELPDV-TEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQ-- 1953
             ++ EK      + + DV T  + +        D +T   T P+   S  E  SV +   
Sbjct: 8044 TTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTP 8103

Query: 1954 --------QELPDSHLTEEALKVSP---VSIPAEQKT---GIPIGLSSSYSHSHKEKLKI 1999
                    Q  P S LT    K S     S+  E  T   G+P G               
Sbjct: 8104 GFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTG--------------- 8148

Query: 2000 STVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILF 2059
            +T  +   + T     ++S ++Q+      TV      +T ++    S  +++ +  I  
Sbjct: 8149 ATAEVSRTEVTSSSRTSISGFAQL------TVSPETSTETITRLPTSSIMTESAEMMIKT 8202

Query: 2060 QQQLP-DRDQSKGILKISAVPELTDVNTGKPVSLSSSYFHREKSNIFSPQELPGSHVTED 2118
            Q   P    +S   + IS  P   + ++    +++  + H E + + S    PG  +   
Sbjct: 8203 QTDPPGSTPESTHTVDISTTPNWVETHS----TVTQRFSHSEMTTLVS--RSPGDMLWPS 8256

Query: 2119 VLKVSTIPGPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQ 2178
               V      +   ++  T  PS  S     D F    LP   L    L I++     D+
Sbjct: 8257 QSSVEETSSASSLLSLPATTSPSPVSSTLVED-FPSASLPVTSLLNPGLVITT-----DR 8310

Query: 2179 ITGLQTVPSGTYSHGENHKLVSEHVQRLIDNLNSSDSSVSSNNVLLNSQADDRVVINKPE 2238
            + G+   P GT S         E +  L D +++ D   S++  + N +    +  ++ +
Sbjct: 8311 M-GISREP-GTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTS--ISGHESQ 8366

Query: 2239 SAGFRDVGSEEIQDAENSAKTLKEIRTLLMEAENMALKR------CNFPAPLARFRDISD 2292
            S+   D  + +      +  T+ E    +  ++     R       +  + L        
Sbjct: 8367 SSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSER 8426

Query: 2293 ISFIQSKKVVCFKEPS--STGVSNGDLLHRQPFTEESPSSRCIQKDIGTQTNLKCRRG-I 2349
            IS       V  + PS  +T VS  +++  +  +   P    I  DI T+   +     I
Sbjct: 8427 ISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPI 8486

Query: 2350 ENWEFISSTTVRSPLQEAESKVSMALEETLRQY------QAAKSVMRSEPEGCSGTIGNK 2403
                  S+ T+ +    A S+ ++ L+ +   +       A+     SE           
Sbjct: 8487 MTESAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSRTPGD 8546

Query: 2404 I---IIPMMTVIKSDSSSDASDGNGSCSWDSNLPESLES 2439
            +    +P +    S SSS +S    S S+ S LPES+ S
Sbjct: 8547 VPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISS 8585



 Score = 50.8 bits (120), Expect = 3e-05
 Identities = 204/995 (20%), Positives = 332/995 (33%), Gaps = 109/995 (10%)

Query: 149  DDQKTESWHCLPQEMDSSQTLDTSQTRFNVRTEDTEVTDFPSLEEGILTQSENQVKEPNR 208
            D   T SW   P       T     T F+   EDT     PS+EE   T S + +   + 
Sbjct: 4111 DTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEE---TSSSSSLVPIHA 4167

Query: 209  DLFCSPLLVIQDSFASPDLPLLTCLTQDQEFAPDSLFHQSELSFAPLRGIP--------- 259
                S +L+     +    P +T +   +          S +S  P   +P         
Sbjct: 4168 TTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGE 4227

Query: 260  -----DKSEDTEWSSRPSEVSEALFQATAEVASDL-ASSRFSVSQHPLIGSTAVG---SQ 310
                 + S DT+     ++ +    +AT+   S +   ++ S +  PL+ S  +G   S 
Sbjct: 4228 ALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTKPSKATSPLVTSHIMGDITSS 4287

Query: 311  CPFLPSEQGNNEETISSVDELKIPKDCDRYDDLCSYMSWKTRKDTQWPENNLADKDQVSV 370
                 S +    ET+SSV++    +   +     +  S      +         K Q + 
Sbjct: 4288 TSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVSSGDATTHVTKTQATF 4347

Query: 371  ATSFDITD-ENIATKRSDHFDAARSYGQYWTQEDSSKQAETYLT----KGLQGKVESDVI 425
            ++   I+      T  +   D + +        +SS    T  T       QG    D  
Sbjct: 4348 SSGTSISSPHQFITSTNTFTDVSTNPSTSLIMTESSGVTITTQTGPTGAATQGPYLLDTS 4407

Query: 426  TLDGLNENAVVC------SERVAELQRKP----------TRESEYHSSDLRMLRMSPDTV 469
            T+  L E  +        SE+   + + P            E+ Y SS   +      T+
Sbjct: 4408 TMPYLTETPLAVTPDFMQSEKTTLISKGPKDVSWTSPPSVAETSYPSS---LTPFLVTTI 4464

Query: 470  PKAPKHLKAGDTSKGGIAKVTQSNLKSGITTT---------PVDSDIGSHLSLSLEDLSQ 520
            P A   L+   TS    A    S L SG+  T         PV +   +  + S E L+ 
Sbjct: 4465 PPATSTLQGQHTSSPVSA---TSVLTSGLVKTTDMLNTSMEPVTNSPQNLNNPSNEILAT 4521

Query: 521  LAVSSPLETT-TGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHR 579
            LA ++ +ET     +    N  T +  H+   TL V++ P      TAT  ++ +S    
Sbjct: 4522 LAATTDIETIHPSINKAVTNMGTASSAHVLHSTLPVSSEP-----STATSPMVPASSMGD 4576

Query: 580  GKPSIFYQQGLPDSHLTE-EALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELP 638
               SI     +P S  T+ E    S+      + + +  + ST+ S+             
Sbjct: 4577 ALASI----SIPGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVGAITE 4632

Query: 639  ESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSA 698
             + +     + +  P P  Q T  P + S + S + +         P   ++        
Sbjct: 4633 ATKMEVPSFDATFIPTPA-QSTKFPDIFSVASSRLSN--------SPPMTISTHMTTTQT 4683

Query: 699  VSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQT---EETLTKVSATPGPADQKT 755
             S  A  K   A   ST  +    P +   + FA S  T      +  VS T  P   + 
Sbjct: 4684 GSSGATSKIPLALDTSTLETSAGTPSV-VTEGFAHSKITTAMNNDVKDVSQTNPPFQDEA 4742

Query: 756  EIPAVQSSSYSQREKPSILYPQDLADSHLP---EEGLKVSAVAGPADQKTGLPTVPSSAY 812
              P+ Q+         S+ +      +  P      L  S V       T L TV SS  
Sbjct: 4743 SSPSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDTSLETVTSSPQ 4802

Query: 813  SHREKL--LVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSA 870
            S    L  +     A  D      ++     +       GT      S ++ S   +PS 
Sbjct: 4803 SMSNTLDDISVTSAATTDIETTHPSINTVVTN------VGTTGSAFESHSTVSAYPEPSK 4856

Query: 871  FYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLFPE 930
                 +  S + +  +  SI       +T   +  S     RE  I  SQ+         
Sbjct: 4857 VTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSI--SQEITSSTETST 4914

Query: 931  EALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLTD 990
               K    +     +T   + SS S    ++S+V     L  S      L  S I   + 
Sbjct: 4915 VPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTV----SLDISTETNTRLSTSPIMTESA 4970

Query: 991  QKTVPTPTVPSGSFSH---REKPSIFYQQEWPDSYATE--KALKVSTGPGPADQK---TE 1042
            + T+ T T P G+ S       PS    Q    S  T     L V+T      Q    T 
Sbjct: 4971 EITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTS 5030

Query: 1043 IPAVQSSSYPQR--EKPSVLYPQVLSDSHLPEESL 1075
             P+V  +S P      P++  P ++S S LPE+ L
Sbjct: 5031 PPSVDKTSSPSSFLSSPAMTTPSLIS-STLPEDKL 5064



 Score = 50.4 bits (119), Expect = 4e-05
 Identities = 394/1968 (20%), Positives = 689/1968 (35%), Gaps = 368/1968 (18%)

Query: 490   TQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHT----DTLNQKTLAD 545
             + S + + ++ TP D    SH S+     +  ++SSP+ T++   +    D+++  +L  
Sbjct: 9115  SHSQMTALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPV 9174

Query: 546   THL-------TEETLKVTAIPEPAD---------------------QKTATPTVLSSSHS 577
             T L       T E L  ++ PE +                      +K     V++S ++
Sbjct: 9175  TSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYT 9234

Query: 578   HRGKPSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQEL 637
             H    S+     L DS  T    K +++ G+   T   + LTST                
Sbjct: 9235  HESPSSV-----LADSVTT----KATSSMGITYPTGDTNVLTST-------------PAF 9272

Query: 638   PESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTD----QA 693
              +++  +   ++S  PG +E      T S+T  S V         ++P G  T+    +A
Sbjct: 9273  SDTSRIQTKSKLSLTPGLMETSISEETSSATEKSTV-------LSSVPTGATTEVSRTEA 9325

Query: 694   LKVS--AVSGPA------DQKTGTATVLSTPHSHREK-----------PGIFYQQEFA-D 733
             +  S  ++ GPA      D    T T +STP + +E             G   Q  F  D
Sbjct: 9326  ISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGATSQGTFTLD 9385

Query: 734   SHQTEETLTKVSAT----------------------PGPADQKTEIPAVQSSSYSQREKP 771
             S  T       SAT                      P P   +   P     S S    P
Sbjct: 9386  SSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSP 9445

Query: 772   SILYPQDLADSH---LPEEGLKVSAVAGPADQ-KTGLPTVPSSAYSHREKLLVFYQQALL 827
             S LY      SH   +P   L  S +    D     L    +SA      + +   ++L 
Sbjct: 9446  SPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDASLEPETTSA----PNMNITSDESLA 9501

Query: 828   DSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALK 887
              S    E   +      A     T + T    +SS    +P+      + +S + +  + 
Sbjct: 9502  ASKATTETEAIHVFENTAASHVETTSATEELYSSSPGFSEPTKVISPVVTSSSIRDNMVS 9561

Query: 888   VSIVPGPGDQKTGIPSAPSSFYSHRE----KPIIFSQQT------LPDFLFPEEALKVSA 937
              ++    G  +  I S  S     RE    + I  S +T      +P    PE    VS 
Sbjct: 9562  TTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYKMPSGATPE----VSR 9617

Query: 938   VSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPG-----LTDQK 992
               V+ + +T  P  + ++ S      V     L  S +  ES +++          T Q 
Sbjct: 9618  TEVMPSSRTSIPGPAQSTMSLDISDEVV--TRLSTSPIMTESAEITITTQTGYSLATSQV 9675

Query: 993   TVP----------TPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTE 1042
             T+P          T +  S   SH E  ++      P+S +      V T    +   T 
Sbjct: 9676  TLPLGTSMTFLSGTHSTMSQGLSHSEMTNL--MSRGPESLSWTSPRFVET-TRSSSSLTS 9732

Query: 1043  IPAVQS---------SSYPQREKP--SVLYP------QVLSDSHLPEESLKVS------A 1079
             +P   S          S P    P  S++ P      +VL  S  P+ S   +       
Sbjct: 9733  LPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVE 9792

Query: 1080  FPGPADQMTDTPAV-PSTFYSQREKPGIFYQQTLPESH---LPKEALKISV-APGLADQK 1134
              P  ++ MTDT  + PS   S      +    ++ ESH   L      I++ + G+    
Sbjct: 9793  IPATSEIMTDTEKIHPS---SNTAVAKVRTSSSVHESHSSVLADSETTITIPSMGITSAV 9849

Query: 1135  TGTPTVTST-SYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFY 1193
               T   TS  ++S+ R  P+       PG      +++ +++T        +P   +T  
Sbjct: 9850  DDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYGVPTSATTEV 9909

Query: 1194  SQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQV 1253
             S  E   I     +   HIP+  Q  S +      +  T   +S+  S + +  I  Q+ 
Sbjct: 9910  SMTE---IMSSNRI---HIPDSDQ--STMSPDIITEVITRLSSSSMMSESTQMTITTQKS 9961

Query: 1254  LPDNHPTEEALKISVASEPVDQTTGT------PAVTSTSYSQYREKP----SIFYQQSLP 1303
              P     +  L ++  + P+ +T  T       +  +T  S+  E P    S+F +++  
Sbjct: 9962  SP-GATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSS 10020

Query: 1304  SSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTE--KPGVFYQQVLPHSHPTEEALKI 1361
             SS L     ++     P+   T+   +PS+ +S T    PG+   +    S     +L  
Sbjct: 10021 SSSLL----SLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMV--KTTDTSTEPGTSLSP 10074

Query: 1362  SVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTG 1421
             +++   V+    +   T T     +   ++    +    H    + ++ + P       G
Sbjct: 10075 NLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVG 10134

Query: 1422  IPTLPSTFYSHTEKPGSFYQ---QVLPHSHLPEEALEVSVAPGPVDQTIGTPTVT----- 1473
              P+  +     T  P +F     +  P SHL     + +++   +D +  TPT T     
Sbjct: 10135 TPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMS---LDTSSVTPTNTPSSPG 10191

Query: 1474  -----------------------SPSSSFGEKPIVIYK--------------QAFPEGH- 1495
                                     P+S + E P+ I                 +FPE   
Sbjct: 10192 STHLLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRF 10251

Query: 1496  ---LPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAK-SGSFYQLALLGSQIPEEALRV 1551
                + E +  +S    P  +T    T+  PS S+     + +    A+ GS  P    R 
Sbjct: 10252 TMSVTESTHHLSTDLLPSAETISTGTV-MPSLSEAMTSFATTGVPRAISGSGSPFS--RT 10308

Query: 1552  SSAPGPADQTT---GIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKK 1608
              S PG A  +T    +P+ T   +S       +     P       AL     S  T  +
Sbjct: 10309 ESGPGDATLSTIAESLPSSTPVPFSSSTFTTTD-SSTIP-------ALHEITSSSATPYR 10360

Query: 1609  TDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSN 1668
              D   G   S+  G   +     + LD+  + +  + S++P    + TE++ +  T  S 
Sbjct: 10361 VDTSLGTESSTTEGRLVMV----STLDT--SSQPGRTSSSPILDTRMTESVEL-GTVTSA 10413

Query: 1669  RGKPVIFYQQTLSD------SHLPEEAL---KVPPVPGPDAQKTETPSVSSSLYSYREKP 1719
                P +  + T +D      + +P EA     + PV GP  Q + +P+    L++   K 
Sbjct: 10414 YQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGP--QTSTSPASPKGLHTGGTKR 10471

Query: 1720  IVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHT----EKPNISYQ--QE 1773
             +          E T  ALK +     A + T  +T+T+S Y+ T       N S Q    
Sbjct: 10472 M----------ETTTTALKTTTT---ALKTTSRATLTTSVYTPTLGTLTPLNASMQMAST 10518

Query: 1774  LPDSHLTEEALKVSNVPGPADQ-KTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKIL 1832
             +P   +        +VP       T +   TST+   R  P V + RE    +E    ++
Sbjct: 10519 IPTEMMITTPYVFPDVPETTSSLATSLGAETSTALP-RTTPSV-FNRE----SETTASLV 10572

Query: 1833  RVPGPADQKTGINILP-SNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQI 1891
                G A++   I  L  S+S P    S + +  E       T+  +    P    + +  
Sbjct: 10573 SRSG-AERSPVIQTLDVSSSEPDTTASWVIHPAE-------TIPTVSKTTPNFFHSELDT 10624

Query: 1892  ASSSSYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVI 1951
              SS++ S+    S      +     +AL   V     D  T  PT+  S +    + + +
Sbjct: 10625 VSSTATSHGADVSSAIPTNISPSELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTWL 10684

Query: 1952  SQ---------QELPD-SHLTEEALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKIST 2001
             +          + +P+ SH   +A      S  AE  + IPI    + S   ++ +    
Sbjct: 10685 THPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPI---MTVSPGAEDLVTSQV 10741

Query: 2002  VHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQ 2061
                  D+    P  TLS     E   I++++   + +T S        + T+ P +    
Sbjct: 10742 TSSGTDRNMTIPTLTLSPG---EPKTIASLVTHPEAQTSSAIP-----TSTISPAV---S 10790

Query: 2062  QLPDRDQSKGILKISAVPELTDVNTGKPVSLSSSYFHREKSNIFSPQELP-GSHVTEDVL 2120
             +L     +    K S        + G+P +  S   H  +++   P       H   D  
Sbjct: 10791 RLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTT 10850

Query: 2121  KVSTIPGPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDRHLTEDALKISSALGQADQIT 2180
                T    A   + +PT   S+    E P +        R +    + I + L   +   
Sbjct: 10851 PSMTTSHGAESSSAVPTPTVST----EVPGVVTPLVTSSRAVISTTIPILT-LSPGEP-- 10903

Query: 2181  GLQTVPSGTYSHGENHK------LVSEHVQRLIDNLNSSDSSVSSNNV 2222
               +T PS   SHGE          VS  V  ++ +L +S  +V+S  +
Sbjct: 10904 --ETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTI 10949



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 351/1721 (20%), Positives = 586/1721 (34%), Gaps = 287/1721 (16%)

Query: 528  ETTTGQHTDTLNQKTLADTHL-TEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSI-F 585
            E  +G    TL+ KT     + TE TL  T+     D+  A+PT   SS   R   S+  
Sbjct: 29   EMDSGLTGATLSPKTSTGAIVVTEHTLPFTS----PDKTLASPT---SSVVGRTTQSLGV 81

Query: 586  YQQGLPDSH---LTEEALKVSAAPGLADQTTGMSTLT---STSYSHREKPGTFYQQELPE 639
                LP+S    +T    + S  P L+ Q  G  +     ++  S    P T  +    E
Sbjct: 82   MSSALPESTSRGMTHSEQRTS--PSLSPQVNGTPSRNYPATSMVSGLSSPRT--RTSSTE 137

Query: 640  SNLTEEP----LEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQ-----TLPDGHLT 690
             N T+E     L V    GPV +K  +PT +ST+     +  +  R      T P     
Sbjct: 138  GNFTKEASTYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFA 197

Query: 691  DQALKVSAVSGPADQKTGTATVLSTPHSHREKP--GIFYQQEFAD-------SHQTEETL 741
            D     S  + P        TV  +    R  P  G  Y   F D       + + E +L
Sbjct: 198  DST--ASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLY-SSFLDLSPKGTPNSRGETSL 254

Query: 742  TKVSAT---------PGPADQ---KTEIPAVQSSSY--SQREKPSILYPQDLAD------ 781
              + +T         PG A      T  P   S+S   ++  + SI   Q L        
Sbjct: 255  ELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGV 314

Query: 782  -----SHLPEEGLKVSAVAGPADQK--------TGLPTVPSSAYSHREKLLVFYQQA--- 825
                 S +P   +  S     A+          + L T   S     E +L F+  A   
Sbjct: 315  PEARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETM 374

Query: 826  -LLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQ------QTLPN 878
             +  +H+ +        S    G T T A+T+TS +++ + E+ +  +       +   N
Sbjct: 375  DIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLN 434

Query: 879  SHLT---------EEALKVSIVPGPG----DQKTGIPSAPSSFYSHREKPIIFSQQ-TLP 924
            + +T         E  +  ++VP  G    D K   PS  SS +  RE     S      
Sbjct: 435  TSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQS 494

Query: 925  DFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSA 984
                   +  +   +  +  K  + T  S +   SE     + +  P       S+K   
Sbjct: 495  SSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSP-------SMKTER 547

Query: 985  IPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIP 1044
             P  T      T +VPS         +   +  W +  + +  +  ST  GP   +  +P
Sbjct: 548  PPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGESTA-GPTTHQFAVP 606

Query: 1045 AVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKP 1104
               S +     + S     +L+ +    E+            ++ +PAV  T        
Sbjct: 607  TGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPG 666

Query: 1105 GIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTH 1164
            G     T+  S +P+ +   S A         TP  T   +S   E  S  H +      
Sbjct: 667  GTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHPFSS-PEPDSAGHTKISTSIP 725

Query: 1165 IPEEA----QKVSAVTGPGNQKTWIPRVLST-FYSQREKPGIFYQQTLPGSHIPEEAQKV 1219
            +   A     KVSA +   + K        T   S + KP      ++  S+     ++V
Sbjct: 726  LLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTLSNAATSPERV 785

Query: 1220 ----SPVLGPA---DQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEP 1272
                SP+  P+   ++  G+    S S   T+ P I         HPT     ++  S  
Sbjct: 786  RNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNI---------HPTG---TLTSESSE 833

Query: 1273 VDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHL------TEEAKNVSAVPGPADQKTV 1326
               T   P+V+    +         +  S PS+HL      TEE  N    P  +  +T 
Sbjct: 834  SPSTLSLPSVSGVKTT---------FSSSTPSTHLFTSGEETEETSN----PSVSQPETS 880

Query: 1327 IPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHT 1386
            +  + +T  S +    VF       + PT  A   S  S  V +   T + TS + S  +
Sbjct: 881  VSRVRTTLASTSVPTPVFPTM---DTWPTRSAQFSS--SHLVSELRATSS-TSVTNSTGS 934

Query: 1387 EKPSIFY-QQSLPGSHLTEEAKNVSAVPGPGD-------RKTGIPTLPSTFYSHTEKPGS 1438
              P I +   +   S    +  N SA P            KTG+P+  +T  S +    S
Sbjct: 935  ALPKISHLTGTATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTT-VSTSATSLS 993

Query: 1439 FYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSS-SFGEKPIVIYKQAFPEGHLP 1497
                V   +     ++E +    P    + T T   P S +     I I K    EG L 
Sbjct: 994  ATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKGYITEGRLD 1053

Query: 1498 EESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGP 1557
               L       P+G T  + T    + ++               S  P +++  + +  P
Sbjct: 1054 TSHL-------PIGTTASSETSMDFTMAKESVSM----------SVSPSQSMDAAGSSTP 1096

Query: 1558 ADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIP-AGPL 1616
               +  + T +   Y    + I           +P +    ++    T      P  G  
Sbjct: 1097 GRTSQFVDTFSDDVYHLTSREIT----------IPRDGTSSALTPQMTATHPPSPDPGSA 1146

Query: 1617 GSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNR-GKPVIF 1675
             S+ LG          +L S  +    KV+ +   + Q+  T  +  T  ++R   P + 
Sbjct: 1147 RSTWLG----------ILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLP 1196

Query: 1676 YQQTLSDSHLPEEAL--KVPPVPGPDAQKTETPSVSSSLYSYRE--KPIVFYQQALPDSE 1731
               +L+ S++P      K   VP       +TPS ++SL +       +  Y ++     
Sbjct: 1197 STTSLTPSNIPTSGAIGKSTLVP------LDTPSPATSLEASEGGLPTLSTYPESTNTPS 1250

Query: 1732 LTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPG 1791
            +   A   S  P    + T  S V    Y+    P+I     +  + +   +     +  
Sbjct: 1251 IHLGAHASSESPSTI-KLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTA 1309

Query: 1792 PADQKTGVSTVTSTSY--SHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPS 1849
            P +  TG ST   T+Y  +   K   S Q   PH     ++ LR        T  N   +
Sbjct: 1310 PGETNTG-STWDPTTYITTTDPKDTSSAQVSTPH----SVRTLR--------TTENHPKT 1356

Query: 1850 NSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQ 1909
             S     +S        P+LT    KA  +    +  T +     +     EK+S F  Q
Sbjct: 1357 ESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLA-----EKSSGFETQ 1411

Query: 1910 ELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVS 1969
              P               G     IPT P    S  E  S +  + L             
Sbjct: 1412 SAP---------------GPVSVVIPTSPTIGSSTLELTSDVPGEPL------------- 1443

Query: 1970 PVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKIS 2029
             V  P+EQ T I + +++  S S  E++  + + I        P++ +S+++    P +S
Sbjct: 1444 -VLAPSEQTT-ITLPMATWLSTSLTEEMASTDLDISS------PSSPMSTFAIF--PPMS 1493

Query: 2030 TVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPELTDVN-TGK 2088
            T      +     +A  ++ S T+             DQ  GI  +    +LT V  T  
Sbjct: 1494 TPSHELSKSEADTSAIRNTDSTTL-------------DQHLGIRSLGRTGDLTTVPITPL 1540

Query: 2089 PVSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIPGPA 2129
              + +S   H  ++       +  +HVT+ +   ++IP  A
Sbjct: 1541 TTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASA 1581



 Score = 40.4 bits (93), Expect = 0.037
 Identities = 339/1746 (19%), Positives = 577/1746 (33%), Gaps = 281/1746 (16%)

Query: 490  TQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLT 549
            TQS    GI   P  ++ G    +S       A +S    TT   T  + Q TL      
Sbjct: 2840 TQSTAPKGIPVKPTSAESGLLTPVSASSSPSKAFAS---LTTAPPTWGIPQSTL------ 2890

Query: 550  EETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHLTEEALKVSAAPGLA 609
              T + + +P    +  + PT   S ++            +PDS  +  +  +S +P   
Sbjct: 2891 --TFEFSEVPSLDTKSASLPTPGQSLNT------------IPDSDASTASSSLSKSPEKN 2936

Query: 610  DQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTS 669
             +   M++  + S S  +  G     E PE + +  P      P      TG P  +S S
Sbjct: 2937 PRARMMTSTKAISASSFQSTGF---TETPEGSAS--PSMAGHEPRVPTSGTGDPRYASES 2991

Query: 670  HSHVEDLLFFYRQT-------LPDGHLTDQALKVSAVSGPADQKTGTAT-VLSTPHSHRE 721
             S+ +        T       L     T QA +  + S P    T   T  LS   S   
Sbjct: 2992 MSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKETSFLSPTASTSR 3051

Query: 722  KPGIFYQQEFADSHQTEETLTKVSATPGPAD----QKTEIPAVQSSSYSQREKPSILYPQ 777
            K  +F     A        L   + T  P       + E P + SS     E+ +    Q
Sbjct: 3052 KTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQ 3111

Query: 778  DLA--DSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREK--------------LLVF 821
             L    S  P   L VS+   P  ++   P   +S+ S   K              + + 
Sbjct: 3112 TLTFTPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMS 3171

Query: 822  YQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHL 881
             Q A  +S  P  A +    S PA    G+P +++T    SS     S   + T+ NS  
Sbjct: 3172 SQAAQGNSTWPAPAEETG--SSPAGTSPGSPEMSTTLKIMSSKEPSISPEIRSTVRNS-- 3227

Query: 882  TEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVL 941
                            KT   + P              + T+        AL   + S+ 
Sbjct: 3228 --------------PWKTPETTVP-------------METTVEPVTLQSTALGSGSTSI- 3259

Query: 942  AAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPS 1001
            +   TGT   +S + S +E      +  L  S     +   S  PG T Q      +V  
Sbjct: 3260 SHLPTGT---TSPTKSPTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSL 3316

Query: 1002 GSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLY 1061
             S + R       QQ  P+  +    ++ S   G     T    V  S+     +  V  
Sbjct: 3317 ESPTARSITGT-GQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTS 3375

Query: 1062 PQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEA 1121
            P   S S L ++S          +    T A+PST  + +       QQT   S    EA
Sbjct: 3376 PN--SVSSLTDKS------KHKTETWVSTTAIPSTVLNNKIMAA--EQQT---SRSVDEA 3422

Query: 1122 LKISVAPGLADQKTG-------TPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSA 1174
               S     +DQ +G       +P VT+T Y            Q      +P   Q +++
Sbjct: 3423 --YSSTSSWSDQTSGSDITLGASPDVTNTLYITST-------AQTTSLVSLPSGDQGITS 3473

Query: 1175 VTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPT 1234
            +T P   KT       +  S    P I  +     +++      ++P  G   Q +    
Sbjct: 3474 LTNPSGGKT-------SSASSVTSPSIGLETL--RANVSAVKSDIAPTAGHLSQTSSPAE 3524

Query: 1235 PTSASYSHTEKPGIFYQ-QVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREK 1293
             +    +    PGI      +  N  +       V    +D T  T   T+++     E 
Sbjct: 3525 VSILDVTTAPTPGISTTITTMGTNSISTTTPNPEVGMSTMDSTPATERRTTST-----EH 3579

Query: 1294 PSIFYQQSLPSS-HLTEEAKNVSAVPGPADQKTVIPI--------LPSTFYSHTEKPGVF 1344
            PS +   +   S  +T+   N+     P    T+           L S    H     + 
Sbjct: 3580 PSTWSSTAASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIG 3639

Query: 1345 YQQVLPHSHPTEEALKISVAS---EPVDQTTGTPTVT-STSYSQHTEKPSIFYQQSLPGS 1400
               V P S  +    + S +     P D T  TP  T S         P I      P S
Sbjct: 3640 TSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSS 3699

Query: 1401 HLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAP 1460
               E+             KT   T  STF          +  +         +L  + A 
Sbjct: 3700 TEAEDVPVSMVSTDHASTKTDPNTPLSTF---------LFDSLSTLDWDTGRSLSSATAT 3750

Query: 1461 GPVDQTIGTP------TVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTT 1514
                Q   TP      T+ SP++S         +  F  GH+       +V P  + +++
Sbjct: 3751 TSAPQGATTPQELTLETMISPATS---------QLPFSIGHITS-----AVTPAAMARSS 3796

Query: 1515 GAPTITSPSYSQHRAKSGSFYQLALLGS----QIPEEAL-------RVSSAPGPADQTTG 1563
            G  T + P  +  +A+  S  QL    S    Q+P  A          +  P    Q  G
Sbjct: 3797 GV-TFSRPDPTSKKAEQTS-TQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQG 3854

Query: 1564 IPTIT----STSYSFGEKP--------IVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDI 1611
               +T    +TS S+ EK         I     +  +  + E     S++        ++
Sbjct: 3855 QTALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINL 3914

Query: 1612 PAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSA--------APGPADQKTETLPVHS 1663
             +G   S +    P  + R A  +S  +KE +  S                   T+P HS
Sbjct: 3915 ESGTTSSPSWKSSP--YERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAHS 3972

Query: 1664 TSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYREKPIVFY 1723
             S S    PV+      + S   +  + +     P++ +  T   S      R+      
Sbjct: 3973 AS-SKLTSPVV------TTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMD 4025

Query: 1724 QQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPD----SHL 1779
              +   + +       +    P  + T    ++SSF + + + + S  + +        +
Sbjct: 4026 TSSTTQTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAITRLSNFPAM 4085

Query: 1780 TEEA---LKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPG 1836
            TE     L +   P  A   +  +  TS + S    P+ + QR    FT +    L   G
Sbjct: 4086 TESGGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATTQR----FTYSEKTTLFSKG 4141

Query: 1837 PAD-----------QKTGINILPSNSYPQREHSVISYEQELP------------------ 1867
            P D             +  +++P ++     + +++ +   P                  
Sbjct: 4142 PEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSGLG 4201

Query: 1868 ---DLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALNVFVV 1924
               D++ ++L+  G   P +  +    A S+  ++R+  +I H  +      EA +    
Sbjct: 4202 KTTDMSRISLEP-GTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYS 4260

Query: 1925 PGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTGIPIG 1984
            P  G  K    T PL   +      + S   +  S  T E   VS V+   ++++   + 
Sbjct: 4261 PIPGHTKPSKATSPL--VTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVA 4318

Query: 1985 LSSSYSHSHKEKLKI--STVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTPSQ 2042
             S++ + +    +    +T H+   Q T     ++SS  Q     I++     D  T   
Sbjct: 4319 SSATETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQF----ITSTNTFTDVSTNPS 4374

Query: 2043 TAFHSSYSQTVKPNILFQQQLPDRDQSKG--ILKISAVPELTDVNTGKPVSLSSSYFHRE 2100
            T+   + S  V    +  Q  P    ++G  +L  S +P LT+     P++++  +   E
Sbjct: 4375 TSLIMTESSGV---TITTQTGPTGAATQGPYLLDTSTMPYLTET----PLAVTPDFMQSE 4427

Query: 2101 KSNIFS 2106
            K+ + S
Sbjct: 4428 KTTLIS 4433



 Score = 40.4 bits (93), Expect = 0.037
 Identities = 137/709 (19%), Positives = 246/709 (34%), Gaps = 96/709 (13%)

Query: 223   ASPDLPLLTCLTQDQEFAPDSLFHQSELSFAPLRGIPDKSEDTEWSSRPSEVSEALFQAT 282
             AS  +P LT  T  + F   SL      S + L     +   +E  + PS V+    +++
Sbjct: 11246 ASSVVPTLTVST-GEPFTNISLVTHPAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESS 11304

Query: 283   AEVASDLASSRFSVSQHPLIGSTA-VGSQCPFLPSEQGNNEETIS-----SVDELKIPKD 336
             + +++ ++     V    +  S   + +  P +P     +E T S     +V    +P+ 
Sbjct: 11305 SAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHPAVTSTTVPRT 11364

Query: 337   CDRYDDLCSYMSWKTRKDTQWPENNLADKDQVSVATSFDITDENIATKRSDHFDAA---- 392
                Y    S+    T           A  D  ++  S D+ D   +   S   D +    
Sbjct: 11365 TPNY----SHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIP 11420

Query: 393   ---RSYGQYWTQEDSSKQAETYLTKGLQ--------GKVESDVITLDGLNENAVVCSERV 441
                 S G+  T       +ET+ +  +          K+ + ++   G +      +   
Sbjct: 11421 TLTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTE 11480

Query: 442   AELQRKPTRESEYHSSDLRMLRMSPDTVPKAPKHLKAGDTSKGGIAKVTQSNLKSGITTT 501
                + + T     H ++     M P T PK   H K+  T    I         S ++TT
Sbjct: 11481 TPYEPETTAIQLIHPAETNT--MVPRTTPKF-SHSKSDTTLPVAITS-PGPEASSAVSTT 11536

Query: 502   PVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLKVTAIPEP 561
              +  D+        + ++ L  SS  +T+T          TL++T    ET   T +  P
Sbjct: 11537 TISPDMS-------DLVTSLVPSSGTDTST-------TFPTLSETPYEPETT-ATWLTHP 11581

Query: 562   ADQKTATPTVLSSSHSHRGK---------PSIFYQQGLPDSHLTEEALKV---SAAPGLA 609
             A+  T     + +  SHRG          P +  + G+P + +      V          
Sbjct: 11582 AETSTTVSGTIPN-FSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSAT 11640

Query: 610   DQTTGMSTLT------STSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIP 663
             D +T + TLT       T+ S    PGT     +P   +       S+ P  +      P
Sbjct: 11641 DTSTAIPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVP------SSEPDTMASWVTHP 11694

Query: 664   TVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKP 723
               +ST  S         R T    H +  A  V A S   +  +   T +S        P
Sbjct: 11695 PQTSTPVS---------RTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPG-----AP 11740

Query: 724   GIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLADSH 783
              +   Q  +    T  T+  ++ +PG  +    +     +  S+    S ++PQ      
Sbjct: 11741 EMVTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQ------ 11794

Query: 784   LPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSG 843
                E      +   A+  T LPT  +S+       L+    + +D   P  +  VSA + 
Sbjct: 11795 -VSETTASLTIRPGAETSTALPTQTTSSLF----TLLVTGTSRVDLS-PTASPGVSAKTA 11848

Query: 844   PADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVP 892
             P     GT   T   +++ SLG   +     T  ++  +   L +++ P
Sbjct: 11849 PLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSP 11897


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 73.2 bits (178), Expect = 5e-12
 Identities = 122/541 (22%), Positives = 226/541 (41%), Gaps = 83/541 (15%)

Query: 916  IIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDL 975
            I+ +  T P  + PE        S   ++ TG   ++ N    ++K +V  ++    ++ 
Sbjct: 527  ILINPGTCPVKVLPELPPVSPVSSTGPSETTG---LTENPTISTKKPTVSIEKPSVTTEK 583

Query: 976  PRESLKMSAIPGLTDQKTVPT--PTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTG 1033
            P    +   IP  T++ T+ T  PT+PS      EKP++    E P +  +EK   ++  
Sbjct: 584  PTVPKEKPTIP--TEKPTISTEKPTIPS------EKPNM--PSEKP-TIPSEKPTILTEK 632

Query: 1034 PGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQM-TDTPA 1092
            P    +K  IP+ + +     EKP+V   +  + +     S++    P     + T+ P+
Sbjct: 633  PTIPSEKPTIPSEKPTI--STEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPS 690

Query: 1093 VPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKP 1152
            +P+      EKP I  ++T+  +  P      +++P      T  PT+ +   +   EKP
Sbjct: 691  IPT------EKPTISMEETIISTEKP------TISPEKPTIPTEKPTIPTEKSTISPEKP 738

Query: 1153 SIFHQQALPGTHIPEEAQKVSAV--TGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGS 1210
            +   ++      IP E   +S    T P  + T  P  L+      EKP I  ++     
Sbjct: 739  TTPTEKPT----IPTEKPTISPEKPTTPTEKPTISPEKLTI---PTEKPTIPTEKPT--- 788

Query: 1211 HIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQ-VLPDNHPTEEALKISVA 1269
             IP E   +S      ++ T   TPT  +   TEKP I  ++  LP    T    + +++
Sbjct: 789  -IPTEKPTIS-----TEEPT---TPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIS 839

Query: 1270 SEPVDQTTGTPAVTSTSYSQYREKPSIFYQQ-SLPSSHLT-----------EEAKNVSAV 1317
            +E +      P +++   +   EKP+I  ++ ++P+  LT           E   +   +
Sbjct: 840  TEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL 899

Query: 1318 PGPADQKTVIPILPSTFYSH----TEKPGVFYQQV--------LPHSHPTEEALKISVAS 1365
              P ++ T+ P  P+         TEKP +  ++         +P   PT    K+++ +
Sbjct: 900  TIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPT 959

Query: 1366 EPVDQTTGTPTVTSTSYSQHTEKPSIFYQQ-SLPGSHLTEEAKNVSAVPGPGDRKTGIPT 1424
            E    +T  PT+ +   +  TEKP+I  ++ ++P   LT         P P    TG+  
Sbjct: 960  EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLT-----ALRPPHPSPTATGLAA 1014

Query: 1425 L 1425
            L
Sbjct: 1015 L 1015


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 73.2 bits (178), Expect = 5e-12
 Identities = 122/541 (22%), Positives = 226/541 (41%), Gaps = 83/541 (15%)

Query: 916  IIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDL 975
            I+ +  T P  + PE        S   ++ TG   ++ N    ++K +V  ++    ++ 
Sbjct: 527  ILINPGTCPVKVLPELPPVSPVSSTGPSETTG---LTENPTISTKKPTVSIEKPSVTTEK 583

Query: 976  PRESLKMSAIPGLTDQKTVPT--PTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTG 1033
            P    +   IP  T++ T+ T  PT+PS      EKP++    E P +  +EK   ++  
Sbjct: 584  PTVPKEKPTIP--TEKPTISTEKPTIPS------EKPNM--PSEKP-TIPSEKPTILTEK 632

Query: 1034 PGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQM-TDTPA 1092
            P    +K  IP+ + +     EKP+V   +  + +     S++    P     + T+ P+
Sbjct: 633  PTIPSEKPTIPSEKPTI--STEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPS 690

Query: 1093 VPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKP 1152
            +P+      EKP I  ++T+  +  P      +++P      T  PT+ +   +   EKP
Sbjct: 691  IPT------EKPTISMEETIISTEKP------TISPEKPTIPTEKPTIPTEKSTISPEKP 738

Query: 1153 SIFHQQALPGTHIPEEAQKVSAV--TGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGS 1210
            +   ++      IP E   +S    T P  + T  P  L+      EKP I  ++     
Sbjct: 739  TTPTEKPT----IPTEKPTISPEKPTTPTEKPTISPEKLTI---PTEKPTIPTEKPT--- 788

Query: 1211 HIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQ-VLPDNHPTEEALKISVA 1269
             IP E   +S      ++ T   TPT  +   TEKP I  ++  LP    T    + +++
Sbjct: 789  -IPTEKPTIS-----TEEPT---TPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIS 839

Query: 1270 SEPVDQTTGTPAVTSTSYSQYREKPSIFYQQ-SLPSSHLT-----------EEAKNVSAV 1317
            +E +      P +++   +   EKP+I  ++ ++P+  LT           E   +   +
Sbjct: 840  TEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL 899

Query: 1318 PGPADQKTVIPILPSTFYSH----TEKPGVFYQQV--------LPHSHPTEEALKISVAS 1365
              P ++ T+ P  P+         TEKP +  ++         +P   PT    K+++ +
Sbjct: 900  TIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPT 959

Query: 1366 EPVDQTTGTPTVTSTSYSQHTEKPSIFYQQ-SLPGSHLTEEAKNVSAVPGPGDRKTGIPT 1424
            E    +T  PT+ +   +  TEKP+I  ++ ++P   LT         P P    TG+  
Sbjct: 960  EKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLT-----ALRPPHPSPTATGLAA 1014

Query: 1425 L 1425
            L
Sbjct: 1015 L 1015


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 72.0 bits (175), Expect = 1e-11
 Identities = 173/868 (19%), Positives = 299/868 (34%), Gaps = 124/868 (14%)

Query: 472  APKHLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSL---EDLSQLAVSSPLE 528
            A KH     T+ G   + T S+   G T T +     SH + S+   E  +    S+ +E
Sbjct: 63   ATKHFLDSSTNSGHSEESTVSHSGPGATGTTL---FPSHSATSVFVGEPKTSPITSASME 119

Query: 529  TTTGQHTDTLNQKTLADTHLTEETLKVTAIPEPADQ-----KTATPTVLSSSHSHRGKPS 583
            TT    + T          L+E++    + P   D+     +T +  V   S +   +P 
Sbjct: 120  TTALPGSTTT-------AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPG 172

Query: 584  IFYQQGLPDSH----LTEEALKVSAAPGLADQTTGMSTLTSTSY-----SHREKPGTFYQ 634
              +    PDS     +++E+    + PG  D T    T T +S      +    PG    
Sbjct: 173  PTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKT 232

Query: 635  QELPESNLTEEPLEVSAAPGPVEQKTGIPTVS---STSHSHVEDLLFFYRQTLPDGHLTD 691
              LP++  T   LE S    PV   TG P  +   S+S +H  +   F  Q+ P    T 
Sbjct: 233  TRLPDNTTTSGLLEAST---PVHSSTGSPHTTLSPSSSTTHEGEPTTF--QSWPSSKDTS 287

Query: 692  QALKVSAVSGPADQKTGTATVLSTPHSH--REKPGIFYQQEFADSHQTEETLTKVSATPG 749
             A   +  +      T  ++  STP +H       + + +E    H +       + TP 
Sbjct: 288  PAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSP---VATATTPP 344

Query: 750  PADQKTEIPAVQSSSY--SQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTV 807
            PA   T     +S++Y  S     ++ +P+    S   EE              T   T 
Sbjct: 345  PARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTA 404

Query: 808  PSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPA-DGKTGTPAVTSTSSASSSLGE 866
              +  S+   L         DS         S +SG + + K    +  + ++     G 
Sbjct: 405  ALAHTSYHSSLGSTETTHFRDS---------STISGRSEESKASHSSPDAMATTVLPAGS 455

Query: 867  KPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDF 926
             PS     + P S ++  +++ + +PG    K G+    ++FYS    P           
Sbjct: 456  TPSVLVGDSTP-SPISSGSMETTALPG-STTKPGLSEKSTTFYSSPRSP----------- 502

Query: 927  LFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDS----DLPRESLKM 982
                        + L A+ T +     ++ SHS   S  +    P S     L +ES   
Sbjct: 503  ----------DTTHLPARMTSSGVSEESTTSHSRPGST-HTTAFPGSTTMPGLSQESTAS 551

Query: 983  SAIPGLTDQKTVPTPTVPSG----SFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPAD 1038
             + PG TD    P  T  S       +    P        PD+      L+ ST    + 
Sbjct: 552  HSSPGPTDTTLSPGSTTASSLGPEYTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSST 611

Query: 1039 QKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTP-AVPSTF 1097
            +        + S  ++ + +  +    S    P      SAF  P+     +P ++P+T 
Sbjct: 612  RSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTH 671

Query: 1098 YSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHR-------- 1149
             S R       +++      P     +           G  + TS S + H         
Sbjct: 672  ISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTT 731

Query: 1150 ----EKPSIFHQQALPG----THIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGI 1201
                E+P+ +H    PG    TH P+     S  +G   + T         +S ++  G 
Sbjct: 732  SALVEEPTSYHSS--PGSTATTHFPDS----STTSGRSEEST-------ASHSSQDATGT 778

Query: 1202 FYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTE 1261
                    + +       SP+   + + T  P  T+        PG+  +     + P  
Sbjct: 779  IVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTT-------PGLSERSTTFHSSPRS 831

Query: 1262 EALKISVASEPVDQTTGTPAVTSTSYSQ 1289
             A  +S AS     ++G    ++TS+S+
Sbjct: 832  PATTLSPAS---TTSSGVSEESTTSHSR 856



 Score = 60.8 bits (146), Expect = 3e-08
 Identities = 186/852 (21%), Positives = 299/852 (35%), Gaps = 153/852 (17%)

Query: 1218 KVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVL-PDNHPTEEALKISVASEPVDQT 1276
            K SP+   + + T  P  T+ +   +EK   FY     PD   +      S  SE    +
Sbjct: 109  KTSPITSASMETTALPGSTTTA-GLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTS 167

Query: 1277 TGTPAVTST-SYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFY 1335
               P  T T ++      P +   Q   +SH    + + +  PG     ++ P   +TF+
Sbjct: 168  HSRPGPTHTIAFPDSTTMPGV--SQESTASHSIPGSTDTTLSPGTTTPSSLGPE-STTFH 224

Query: 1336 SHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTP--TVTSTSYSQHTEKPSIFY 1393
            S    PG      LP +  T   L+   AS PV  +TG+P  T++ +S + H  +P+ F 
Sbjct: 225  S---SPGYTKTTRLPDNTTTSGLLE---ASTPVHSSTGSPHTTLSPSSSTTHEGEPTTF- 277

Query: 1394 QQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEA 1453
             QS P S  T         P P    +    L +T++S    P S      P +H     
Sbjct: 278  -QSWPSSKDTS--------PAPSGTTSAFVKLSTTYHS---SPSS-----TPTTHFSAS- 319

Query: 1454 LEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQT 1513
               S   G  +++  TP  +SP ++    P     ++   GH+ EES     +PG   QT
Sbjct: 320  ---STTLGHSEES--TPVHSSPVATATTPPPA---RSATSGHV-EESTAYHRSPGST-QT 369

Query: 1514 TGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYS 1573
               P   S + S H  +S +F+     GS    +    SS P     TT     TS   S
Sbjct: 370  MHFP--ESSTTSGHSEESATFH-----GSTTHTK----SSTP----STTAALAHTSYHSS 414

Query: 1574 FGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQAL 1633
             G     +++ +       EE+ K S  S      T +PAG   S  +G+          
Sbjct: 415  LGSTETTHFRDSSTISGRSEES-KASHSSPDAMATTVLPAGSTPSVLVGDS--------- 464

Query: 1634 LDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVP 1693
              SP++   ++ +A PG +  K       +T YS+   P          +HLP       
Sbjct: 465  TPSPISSGSMETTALPG-STTKPGLSEKSTTFYSSPRSP--------DTTHLP------- 508

Query: 1694 PVPGPDAQKTETPSVSSSLYSYREKPIVFYQQALPDSE----LTQEALKVSAVPQPADQK 1749
                    +  +  VS    +   +P   +  A P S     L+QE+    + P P D  
Sbjct: 509  -------ARMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTT 561

Query: 1750 TGLSTVTSS-----FYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTS 1804
                + T+S     + +    P  +    LPD + T   L  ++ P  +  ++  +T++ 
Sbjct: 562  LSPGSTTASSLGPEYTTFHSSPGSTETTLLPD-NTTASGLLEASTPVHSSTRSPHTTLSP 620

Query: 1805 TSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSV----I 1860
               + R+    ++       +    K  R   P    T   + PS +      S+    I
Sbjct: 621  AGSTTRQGESTTFH------SWPSSKDTRPAPPT--TTSAFVEPSTTSHGSPSSIPTTHI 672

Query: 1861 SYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKASIFHQQELPDVTEEALN 1920
            S       L E +      PG       +    S + S R + S          T  +  
Sbjct: 673  SARSTTSGLVEESTTYHSSPGSTQT---MHFPESDTTSGRGEES---------TTSHSST 720

Query: 1921 VFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEEALKVSPVSIPAEQKTG 1980
               +       + +   P SY+S    P   +    PDS  T                  
Sbjct: 721  THTISSAPSTTSALVEEPTSYHS---SPGSTATTHFPDSSTTS----------------- 760

Query: 1981 IPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPKISTVIGPNDQKTP 2040
               G S   + SH  +    T+ +P  + T       S+ S I    + T   P    TP
Sbjct: 761  ---GRSEESTASHSSQDATGTIVLP-ARSTNSVLLGESTTSPISSGSMETTALPGSTTTP 816

Query: 2041 S----QTAFHSS 2048
                  T FHSS
Sbjct: 817  GLSERSTTFHSS 828



 Score = 35.8 bits (81), Expect = 0.91
 Identities = 75/337 (22%), Positives = 117/337 (34%), Gaps = 73/337 (21%)

Query: 468 TVPKAPKHLKAGDTSKGGIAKVTQSNLKSGITT--------TPVDSDIGSHLSLSLEDLS 519
           T+P   +   A  +S G     T + L  G TT        T   S  GS  +  L D  
Sbjct: 540 TMPGLSQESTASHSSPGP----TDTTLSPGSTTASSLGPEYTTFHSSPGSTETTLLPD-- 593

Query: 520 QLAVSSPLETTTGQHTDTLNQKTL----ADTHLTEETLKVTAIPEPADQKTATPTVLSS- 574
               S  LE +T  H+ T +  T       T    E+    + P   D + A PT  S+ 
Sbjct: 594 NTTASGLLEASTPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAF 653

Query: 575 ---SHSHRGKPSIFYQQGLPDSH---------LTEEALKVSAAPGL--------ADQTTG 614
              S +  G PS      +P +H         L EE+    ++PG         +D T+G
Sbjct: 654 VEPSTTSHGSPS-----SIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG 708

Query: 615 MSTLTSTSYS----------------------HREKPGTFYQQELPESNLTEEPLEVSAA 652
               ++TS+S                      +   PG+      P+S+ T    E S A
Sbjct: 709 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 768

Query: 653 PGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATV 712
               +  TG   + + S + V   L     T P   ++  +++ +A+ G +    G +  
Sbjct: 769 SHSSQDATGTIVLPARSTNSV---LLGESTTSP---ISSGSMETTALPG-STTTPGLSER 821

Query: 713 LSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPG 749
            +T HS    P          S    E  T   + PG
Sbjct: 822 STTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPG 858


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 70.5 bits (171), Expect = 3e-11
 Identities = 256/1233 (20%), Positives = 397/1233 (32%), Gaps = 152/1233 (12%)

Query: 612  TTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHS 671
            T G+ + T  S S    P +  Q  L  + LT    + +A+ G   + T   T  +TS  
Sbjct: 1229 TIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSS--KPTASSGEPPRPTTAVTPQATSGL 1286

Query: 672  HVEDLLFFYRQTLPDGHLTDQALKVSA------VSGPADQKTGTATVLSTPHSHREKPGI 725
                 L   R T     +T    + +A       +  A   T T   L TP +    P +
Sbjct: 1287 PPTATL---RSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTL 1343

Query: 726  --FYQQEFADSHQTEETLTKVS--ATPGPADQKTEIPAVQSSSYSQREKPSILY--PQDL 779
                 QE   +  T+ T  + +  +T GP   +   P   +++ + + + +  Y  PQ  
Sbjct: 1344 PKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTP 1403

Query: 780  ADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALK-V 838
              +H P          GP    +   T      SH E          L +H+P  +   V
Sbjct: 1404 HTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPE--------TTLPTHVPPFSTSLV 1455

Query: 839  SAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQK 898
            +  +      T     TS S+ S+  G  P     +   ++H        +         
Sbjct: 1456 TPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSS 1515

Query: 899  TGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSH 958
                  P+S +SH       +  T    + P     ++      + +T TP   +NS + 
Sbjct: 1516 FSTNKTPTSLHSH-------TSSTHHPEVTPTSTTTITPNPT--STRTRTPVAHTNSATS 1566

Query: 959  SEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEW 1018
            S     F     P    P  S             T PTP+ P  +      P       +
Sbjct: 1567 SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPP-------F 1619

Query: 1019 PDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVS 1078
              S  T     V T P  A   T   +    S P    P             P  +LK +
Sbjct: 1620 STSLVTPSTHTVIT-PTHAQMAT---SASIHSMPTGTIP-------------PPTTLKAT 1662

Query: 1079 AFPGPADQMTDTPAVPSTFYSQ---REKPGIFYQQTLPESHLPKEALK-ISVAPGLADQK 1134
                 A  MT T +  S   S     +     +  T    H    +    ++ P      
Sbjct: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPN--PTS 1720

Query: 1135 TGTP--TVTSTSYSQHRE-----KPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTW--I 1185
            TGTP  TVT++  SQ R      K S         TH PE     +    P +  T    
Sbjct: 1721 TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRT 1780

Query: 1186 PRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGT-PTPTSASYSHTE 1244
            P   +T  +    P  F   + P    P       PV   + Q T T PTP   S+ HT 
Sbjct: 1781 PVAHTTSATSSRLPTPFTTHSPPTGTTP--ISSTGPVTATSFQTTTTYPTP---SHPHT- 1834

Query: 1245 KPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPS 1304
                     LP + P+     ++ ++  V   T T   TS S              S+P+
Sbjct: 1835 --------TLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASI------------HSMPT 1874

Query: 1305 SHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVA 1364
              +       + +       T  P+ P+T    ++ P  F       S P   +      
Sbjct: 1875 GTIPPP----TTIKATGSTHTAPPMTPTT-SGTSQSPSSFSTAKTSTSLPYHTSSTHHPE 1929

Query: 1365 SEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPT 1424
              P   T  TP  TST     T  P + +  S   S L       S   G     +  P 
Sbjct: 1930 VTPTSTTNITPKHTSTG----TRTP-VAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPM 1984

Query: 1425 LPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPI 1484
              ++F + T  P   + Q    +H+P  +  + V P      I T T  + S+S    P 
Sbjct: 1985 TATSFQTTTTYPTPSHPQTTLPTHVPPFSTSL-VTPSTHTVIITTHTQMATSASIHSTP- 2042

Query: 1485 VIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALL---G 1541
                   P     + +     AP P+  TT   + T  S+S   A S      + L    
Sbjct: 2043 ---TGTVPPPTTLKATGSTHTAP-PMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNS 2098

Query: 1542 SQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEKP--------IVNYKQAFPDGHLPE 1593
            S  P  +   +  P  +  TT + T    S SF   P         V    + P    P 
Sbjct: 2099 SSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPS 2158

Query: 1594 EALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPAD 1653
                 S VS P    T + +G    S+L   P T    ++  SPL        ++P  + 
Sbjct: 2159 VGTSSSFVSAPVH-STTLSSG--SHSSLSTHPTT---ASVSASPL------FPSSPAAST 2206

Query: 1654 QKTETLPVHSTSYSNRGKPVIFYQQTLS---DSHLPEEALKVPPVPGPDAQKTETPSVSS 1710
                TLP   +S       +     T+S    SHL    +  P  P   A     P+ SS
Sbjct: 2207 TIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSS 2266

Query: 1711 SLYSYREKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISY 1770
               + R   +      +P S        V+ +P      + ++ +T+     T  P   +
Sbjct: 2267 QSTTSRSTSLT---TRVPTSGFVSLTSGVTGIP-----TSPVTNLTTRHPGPTLSPTTRF 2318

Query: 1771 QQELPDSH-LTEEALKVSNVPGPADQKTGVSTV 1802
                  +H  T  +  VS++  P     GV +V
Sbjct: 2319 LTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSV 2351



 Score = 67.0 bits (162), Expect = 4e-10
 Identities = 226/1036 (21%), Positives = 336/1036 (32%), Gaps = 141/1036 (13%)

Query: 499  TTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTL-----NQKTLADTHLTEETL 553
            TTT   +    H + S         S+   T T  H  T      + +T   TH+   + 
Sbjct: 1393 TTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFS- 1451

Query: 554  KVTAIPEPADQKTATPT--VLSSSHSHRGKPSIFYQQGLPDSHLTEEALKVSAAPGLADQ 611
              T++  P+     TPT   +++S S+   P+      +P     +       AP +   
Sbjct: 1452 --TSLVTPSTHTVITPTHAQMATSASNHSAPT----GTIPPPTTLKATGSTHTAPPITPT 1505

Query: 612  TTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSA-APGPVEQKTGIPTVSSTSH 670
            T+G S   S S+S  + P + +       +    P   +   P P   +T  P   + S 
Sbjct: 1506 TSGTSQAHS-SFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSA 1564

Query: 671  SHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQE 730
            +       F   + P G     +   S+          T T   TP SH +     +   
Sbjct: 1565 TSSRPPPPFTTHSPPTG-----SSPFSSTGPMTATSFKTTTTYPTP-SHPQTTLPTHVPP 1618

Query: 731  FADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLK 790
            F+ S  T  T T ++ T           A  ++S S    P+   P        P   LK
Sbjct: 1619 FSTSLVTPSTHTVITPTH----------AQMATSASIHSMPTGTIP--------PPTTLK 1660

Query: 791  VSAVAGPADQKTGLPTVPSSAYS--HREKLLVFYQQALLDSHLPEEALKVSAVSGPADGK 848
             +     A   T   +  S A S  +  K           +H  E     +    P    
Sbjct: 1661 ATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS 1720

Query: 849  TGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTE-------EALKVSIVPGPGDQKTGI 901
            TGTP +T T+S +S      S     T  +SH +             SI P      T  
Sbjct: 1721 TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRT 1780

Query: 902  PSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEK 961
            P A ++  +    P  F+  + P    P      S   V A     T T  + SH H+  
Sbjct: 1781 PVAHTTSATSSRLPTPFTTHSPPTGTTPIS----STGPVTATSFQTTTTYPTPSHPHTT- 1835

Query: 962  SSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDS 1021
                    LP + +P  S   S +   T    +PT T  + S S    P+          
Sbjct: 1836 --------LP-THVP--SFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPP---- 1880

Query: 1022 YATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPE--ESLKVSA 1079
              T KA   ST   P    T     QS S     K S   P   S +H PE   +   + 
Sbjct: 1881 -TTIKATG-STHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNI 1938

Query: 1080 FPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPT 1139
             P      T TP   +T  S    P  F   + P    P  +               T  
Sbjct: 1939 TPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS---------------TGP 1983

Query: 1140 VTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKP 1199
            +T+TS+      P+  H Q    TH+P  +   S VT   +       V+ T ++Q    
Sbjct: 1984 MTATSFQTTTTYPTPSHPQTTLPTHVPPFS--TSLVTPSTH------TVIITTHTQMATS 2035

Query: 1200 GIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSH-----TEKPGIFYQQVL 1254
               +  T  G+  P    K +     A   T T + TS ++S           I     L
Sbjct: 2036 ASIH-STPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWL 2094

Query: 1255 PDNHPTEEALKISVASEPVDQTTGTPAVT----STSYSQYREKPSIFYQQSLPSSHLTEE 1310
            P N  +           P   +  TP  T    S+S+S     PS      +PSSH + +
Sbjct: 2095 PQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPST-VSSYVPSSHSSPQ 2153

Query: 1311 AKNVSA------VPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISV- 1363
              + S       V  P    T+     S+  +H     V    + P S      ++ ++ 
Sbjct: 2154 TSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLP 2213

Query: 1364 ----------ASEPVDQTTGTPTVTS--------------TSYSQHTEKPSIFYQQSLPG 1399
                      A  P+   T +PT +S              T+ S HT  P+   Q +   
Sbjct: 2214 HTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHT-APAFSSQSTTSR 2272

Query: 1400 SHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVA 1459
            S         S         TGIPT P T  + T  PG               A   + A
Sbjct: 2273 STSLTTRVPTSGFVSLTSGVTGIPTSPVTNLT-TRHPGPTLSPTTRFLTSSLTAHGSTPA 2331

Query: 1460 PGPVDQTIGTPTVTSP 1475
              PV  ++GTPT TSP
Sbjct: 2332 SAPV-SSLGTPTPTSP 2346



 Score = 35.0 bits (79), Expect = 1.6
 Identities = 48/207 (23%), Positives = 84/207 (40%), Gaps = 12/207 (5%)

Query: 2941 HQMRENHSPLPQGQDSIASDLPSPISLEQCQSKAPGVDDQMNKHHFPLPQGQDCVVEKNN 3000
            +Q+  + SP P    +++S +PS  S  Q  S + G         F         +   +
Sbjct: 2125 NQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSS-----FVSAPVHSTTLSSGS 2179

Query: 3001 QHKPKSHISNINVEAK--FNTVVSQSAPNHCTLAASASTPPSNRKALSCVHITLCPKTSS 3058
                 +H +  +V A   F +  + S     TL  + S+P +    L    +T+ P  SS
Sbjct: 2180 HSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSS 2239

Query: 3059 KLDSGTLDERFHSLDAASKARMNSEFNFDLHTVSSRSLEPTSKLLTSKPVAQDQESLGF- 3117
             L S T+   F S    + A  ++   F   + +SRS   T+++ TS  V+      G  
Sbjct: 2240 HLASSTI--AFPSTPRTT-ASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP 2296

Query: 3118 LGPKSSLDFQVVQPSL-PDSNTITQDL 3143
              P ++L  +   P+L P +  +T  L
Sbjct: 2297 TSPVTNLTTRHPGPTLSPTTRFLTSSL 2323


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 68.9 bits (167), Expect = 1e-10
 Identities = 119/551 (21%), Positives = 206/551 (37%), Gaps = 61/551 (11%)

Query: 998  TVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSS----YPQ 1053
            + PS + +  E+P+ ++    P S AT      ST  G +++ T   + Q ++     P 
Sbjct: 29   SAPSTTSALVEEPTSYHSS--PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 86

Query: 1054 REKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVP---STFYSQREKPGIFYQQ 1110
            R   SVL  +  + S +   S++ +A PG     T TP +    +TF+S    P      
Sbjct: 87   RSTTSVLLGESTT-SPISSGSMETTALPGS----TTTPGLSEKSTTFHSSPRSPATTLSP 141

Query: 1111 -TLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQH----REKPSIFHQQALPG--T 1163
             +   S + +E+      PG         + T+   S+H       P       LP   T
Sbjct: 142  ASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 201

Query: 1164 HIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSH----IPEEAQKV 1219
                  +  ++ + PG+  T +    +T  S  ++   F+    PGS      P+     
Sbjct: 202  TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS--PGSTHTTLFPDSTTSS 259

Query: 1220 SPVLGPADQKTGTPTP-TSASYSHTEKPGIFYQQVLPDNHPTEEALKIS---VASEPVDQ 1275
              V       + T +P T+ S + +  PG+  +      HP       S    A+ PV++
Sbjct: 260  GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEE 319

Query: 1276 TTG---TPAVTSTSY-------SQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKT 1325
            +T    +P  T T++       S + EK +IF+  S P +  T  +   S   G +++ +
Sbjct: 320  STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFH--SSPDASGTTPSSAHSTTSGVSEESS 377

Query: 1326 VIPILPST-----FYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTST 1380
                 P +     F   T   G+  +    HS        +     P   T     V++T
Sbjct: 378  TSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTT 437

Query: 1381 SYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPG-------PGDRKT-GIPTLPSTFYSH 1432
             +S+ +  P+  +  S      +EE+  V + PG       PG   T G+    +TFYS 
Sbjct: 438  YHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGSTTTAGLSEKSTTFYSS 497

Query: 1433 TEKPGSFYQQV-LPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPS----SSFGEKPIVIY 1487
               P +         S + EE+      PG    T    + T P     ++    P  +Y
Sbjct: 498  PRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGQHWIATHNTVPCRLY 557

Query: 1488 KQAFPEGHLPE 1498
              +    HLPE
Sbjct: 558  NTSGRIYHLPE 568



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 128/590 (21%), Positives = 200/590 (33%), Gaps = 84/590 (14%)

Query: 475  HLKAGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQH 534
            H    DT+ G   + T S+     +TT   S   S  S  +E+ +    SSP  T T   
Sbjct: 2    HFPESDTTSGRGEESTTSHS----STTHTISSAPSTTSALVEEPTSYH-SSPGSTATTHF 56

Query: 535  TDTLNQKTLAD----THLTEETLKVTAIPEPADQ-----KTATPTVLSSSHSHRGKPSIF 585
             D+      ++    +H +++      +P  +       ++ T  + S S      P   
Sbjct: 57   PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST 116

Query: 586  YQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEE 645
               GL +   T  +   S A  L+  +T  S ++  S +   +PG+ +    P+S  T  
Sbjct: 117  TTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTT-- 174

Query: 646  PLEVSAAPGPVEQKTGIPTVSSTSHSH--VEDLLFFYRQTLPDGHLTDQALKVSAVSGPA 703
                           G+   S+TSHS     D       T   G   +     S+  G  
Sbjct: 175  --------------PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS-PGST 219

Query: 704  DQ--KTGTATVLS---TPHSHREKPGIFYQQEFADSHQTE---ETLTKVSATPGPADQKT 755
            D     G+ T LS      +    PG  +   F DS  +    E  T+V ++ G + + T
Sbjct: 220  DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTT 278

Query: 756  EIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKT-------GLPT-- 806
              PA  +S   Q E  S  +    A +H        S    P ++ T         PT  
Sbjct: 279  LSPASSTSPGLQGE--STAFQTHPASTHTTPS--PPSTATAPVEESTTYHRSPGSTPTTH 334

Query: 807  --VPSSAYSHREKLLVFYQQALLDSHLPEEA-LKVSAVSGPADGKTGTPAVTST-----S 858
                S+   H EK  +F+         P  A    S VS  +      P  T T     S
Sbjct: 335  FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDS 394

Query: 859  SASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIF 918
            + +S L ++P+  +     +   TE  L  +  P PG   T  P   S+ Y  R      
Sbjct: 395  TTTSGLSQEPTTSHS----SQGSTEATLDTTPSP-PG--TTAAPVEVSTTYHSRPSSTPT 447

Query: 919  SQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQ-ELPDSDLPR 977
            +  +             +  S   + +T     S+ +   SEKS+ FY     PD+ L  
Sbjct: 448  THFSASSTTLGRSEESTTVHSSPGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 507

Query: 978  ESLKMSAI----------PGLTDQKTVPTPTVPSGSF---SHREKPSIFY 1014
             S   S +          PG T     P  T   G     +H   P   Y
Sbjct: 508  ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGQHWIATHNTVPCRLY 557



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 115/568 (20%), Positives = 190/568 (33%), Gaps = 84/568 (14%)

Query: 1371 TTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPT---LPS 1427
            TT T +   ++ S   E+P+ ++  S PGS  T    + S   G  +  T   +      
Sbjct: 23   TTHTISSAPSTTSALVEEPTSYH--SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATG 80

Query: 1428 TFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKP---- 1483
            T         S        S +   ++E +  PG       TP ++  S++F   P    
Sbjct: 81   TIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTT----TPGLSEKSTTFHSSPRSPA 136

Query: 1484 IVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGS--------FY 1535
              +   +     + EES      PG    T    + T+P  S+H   S S          
Sbjct: 137  TTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL 196

Query: 1536 QLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEK-------PIVNYKQAFPD 1588
              +   S   +E+    S+PG  D  T +   ++T+ SFG++       P   +   FPD
Sbjct: 197  PASTTTSGPSQESTTSHSSPGSTD--TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD 254

Query: 1589 GHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAA 1648
                      +  SG  E  T + +   GS      P +     L       +    S  
Sbjct: 255  S---------TTSSGIVEASTRVHSS-TGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 304

Query: 1649 PGPADQKTETLPV-HSTSY--SNRGKPVIFYQQTLSDSHLPEEAL---KVPPVPG--PDA 1700
              P+   T T PV  ST+Y  S    P   +  + + S   E++      P   G  P +
Sbjct: 305  TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 364

Query: 1701 QKTETPSVSSSLYSYREKPIVFYQQALPDSE----LTQE-----------ALKVSAVPQP 1745
              + T  VS    +   +P   +  A PDS     L+QE              +   P P
Sbjct: 365  AHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSP 424

Query: 1746 ADQKTGLSTVTSSFYSH-TEKPNISYQQELPDSHLTEEALKVSNVPGPAD--------QK 1796
                     V+++++S  +  P   +         +EE+  V + PG  +          
Sbjct: 425  PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGSTTT 484

Query: 1797 TGVSTVTSTSYSHREKPI------------VSYQRELPHFTEAGLKILRVPGPADQKTGI 1844
             G+S  ++T YS    P             VS +    H           PG        
Sbjct: 485  AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGQH 544

Query: 1845 NILPSNSYPQREHSVISYEQELPDLTEV 1872
             I   N+ P R ++       LP+L ++
Sbjct: 545  WIATHNTVPCRLYNTSGRIYHLPELAKL 572


>gi|89026265 PREDICTED: mucin 12 [Homo sapiens]
          Length = 978

 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 142/626 (22%), Positives = 239/626 (38%), Gaps = 88/626 (14%)

Query: 1088 TDTPAVP--STFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSY 1145
            T+T A+P  +T     EK   FY    P S     +   + + G++++ T       TS+
Sbjct: 9    TETTALPGSTTTAGLSEKSTTFYSS--PRSPDTTLSPASTTSSGVSEEST-------TSH 59

Query: 1146 SQHREKPSIFHQQALPG-THIPEEAQKVSAV-TGPGNQKTWIPRVLSTFYSQREKPGIFY 1203
            S    +P   H  A PG T +P  +Q+ +A  + PG+  T +    +T  S   +   F+
Sbjct: 60   S----RPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFH 115

Query: 1204 QQTLPGSH----IPEE--AQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQ-QVLPD 1256
                PGS     +P+   A  +     P    TG+P  T +    T + G     Q  P+
Sbjct: 116  SG--PGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPN 173

Query: 1257 NHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNV-- 1314
            +  T  A        P   T+    +++TS+      P+  +  S  +   +EE+  V  
Sbjct: 174  SKDTTPA--------PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHS 225

Query: 1315 -----SAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVD 1369
                 +  P PA   T   +  ST Y  +  PG       P S       + S  S    
Sbjct: 226  SPVATATTPSPARSTTSGLVEESTAYHSS--PGSTQTMHFPESSTASGRSEESRTSH--S 281

Query: 1370 QTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTF 1429
             TT T +   ++ S   E+P+ ++  S PGS  T      S   G  +  T   + P T 
Sbjct: 282  STTHTISSPPSTTSALVEEPTSYH--SSPGSIATTHFPESSTTSGRSEESTASHSSPDT- 338

Query: 1430 YSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQ 1489
               T  P  F       S    E+    ++PG ++ T+ + T T   S+   K  ++Y  
Sbjct: 339  NGITPLPAHFTT-----SGRIAESTTFYISPGSMETTLASTTTTPGLSA---KSTILYSS 390

Query: 1490 AFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEAL 1549
            +      P+++L  S A       +G PT     YSQ  +   + +  +   S + +E+ 
Sbjct: 391  S----RSPDQTL--SPASMTSSSISGEPTSL---YSQAESTHTTAFPASTTTSGLSQEST 441

Query: 1550 RVSSAPGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKT 1609
               S PG  + T    +IT++S  F ++    + Q  P   L   +   + V G +E+ T
Sbjct: 442  TFHSKPGSTETTLSPGSITTSS--FAQEFTTPHSQ--PGSALSTVSPASTTVPGLSEEST 497

Query: 1610 DIPAGPLGSSALG---EKPITFYRQALL---DSP-----------LNKEVVKVSAAPGPA 1652
               + P  +          ++ + Q      DSP              ++ + S A   +
Sbjct: 498  TFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSS 557

Query: 1653 DQKTET--LPVHSTSYSNRGKPVIFY 1676
               T T  LP  ST+    G+P  FY
Sbjct: 558  SDATGTTPLPARSTASDLVGEPTTFY 583



 Score = 51.6 bits (122), Expect = 2e-05
 Identities = 150/697 (21%), Positives = 255/697 (36%), Gaps = 139/697 (19%)

Query: 851  TPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYS 910
            +P  T + ++++S G    +    + P S  T      + +PG   + T   S+P S   
Sbjct: 36   SPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGS--- 92

Query: 911  HREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQEL 970
                    +  TL             +     A   G  + + +S   S ++++     L
Sbjct: 93   --------TDTTL-------------SPGSTTASSLGPESTTFHSGPGSTETTL-----L 126

Query: 971  PDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKV 1030
            PD+      L+ S  P  +   +  T   P+GS + + + + F  Q WP+S  T  A   
Sbjct: 127  PDNTTASGLLEAST-PVHSSTGSPHTTLSPAGSTTRQGESTTF--QSWPNSKDTTPAPPT 183

Query: 1031 STGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDT 1090
            +T        T   +  S+        S    +    + +    +  +  P PA   T  
Sbjct: 184  TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSG 243

Query: 1091 PAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQ-----KTGTPTVTS--T 1143
                ST Y     PG       PES         S A G +++      + T T++S  +
Sbjct: 244  LVEESTAY--HSSPGSTQTMHFPES---------STASGRSEESRTSHSSTTHTISSPPS 292

Query: 1144 SYSQHREKPSIFHQQ--ALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGI 1201
            + S   E+P+ +H    ++  TH PE     S  +G   + T         +S  +  GI
Sbjct: 293  TTSALVEEPTSYHSSPGSIATTHFPES----STTSGRSEEST-------ASHSSPDTNGI 341

Query: 1202 FYQQTLPGSHIPEE---AQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNH 1258
                 LP +H       A+  +  + P   +T   + T+        PG+  +  +  + 
Sbjct: 342  ---TPLP-AHFTTSGRIAESTTFYISPGSMETTLASTTTT-------PGLSAKSTILYSS 390

Query: 1259 PTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVP 1318
                   +S AS      +G P   ++ YSQ     +  +  S  +S L++E+    + P
Sbjct: 391  SRSPDQTLSPASMTSSSISGEP---TSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKP 447

Query: 1319 GPADQKTVIP--ILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPV-----DQT 1371
            G + + T+ P  I  S+F           +   PHS P      +S AS  V     + T
Sbjct: 448  G-STETTLSPGSITTSSFAQ---------EFTTPHSQPGSALSTVSPASTTVPGLSEEST 497

Query: 1372 T--GTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIP-TLPST 1428
            T   +P  T T+   H+   SI  QQS P                PG   T +P TL +T
Sbjct: 498  TFYSSPGSTETTAFSHSNTMSIHSQQSTP------------FPDSPGFTHTVLPATLTTT 545

Query: 1429 --------FYSHTEKPGSFYQQVLP----HSHLPEEALEVSVAPGPVDQTI-----GTPT 1471
                    F+S ++  G+     LP     S L  E     ++P P   T+      T  
Sbjct: 546  DIGQESTAFHSSSDATGT---TPLPARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSG 602

Query: 1472 VTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPG 1508
            +T  S++F   P      +F    +  ESL+ ++APG
Sbjct: 603  LTEESTTFHTSP------SFTSTIVSTESLE-TLAPG 632



 Score = 50.1 bits (118), Expect = 5e-05
 Identities = 137/665 (20%), Positives = 228/665 (34%), Gaps = 81/665 (12%)

Query: 987  GLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAV 1046
            G T+   +P  T  +G     EK + FY    P S  T  +   +T  G +++ T   + 
Sbjct: 7    GSTETTALPGSTTTAGL---SEKSTTFYSS--PRSPDTTLSPASTTSSGVSEESTTSHSR 61

Query: 1047 QSSSYPQREKPSVLYPQVLSDS---HLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREK 1103
              S++      S   P V  +S   H    S   +  PG     +  P   +TF+S    
Sbjct: 62   PGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPE-STTFHSG--- 117

Query: 1104 PGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGT 1163
            PG      LP++      L+ S         TG+P  T +       +      Q+ P +
Sbjct: 118  PGSTETTLLPDNTTASGLLEASTP---VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNS 174

Query: 1164 HIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKV--SP 1221
                   K +    P     ++    ++  S    P   +  +       EE+  V  SP
Sbjct: 175  -------KDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSP 227

Query: 1222 VLG---PADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTG 1278
            V     P+  ++ T      S ++   PG       P++       + S  S     TT 
Sbjct: 228  VATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSH--SSTTH 285

Query: 1279 TPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPST----- 1333
            T +   ++ S   E+P+ ++  S P S  T      S   G +++ T     P T     
Sbjct: 286  TISSPPSTTSALVEEPTSYH--SSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITP 343

Query: 1334 FYSHTEKPGVFYQQVLPHSHP-TEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIF 1392
              +H    G   +    +  P + E    S  + P      T   +S+     T  P+  
Sbjct: 344  LPAHFTTSGRIAESTTFYISPGSMETTLASTTTTPGLSAKSTILYSSSRSPDQTLSPASM 403

Query: 1393 YQQSLPG--SHLTEEAKNVSAVPGPGDRKT-GIPTLPSTFYSHTEKPGSFYQQVLPHSHL 1449
               S+ G  + L  +A++      P    T G+    +TF+S   KPGS           
Sbjct: 404  TSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHS---KPGS----------- 449

Query: 1450 PEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGP 1509
                 E +++PG +  +      T+P S  G     +   +     L EES     +PG 
Sbjct: 450  ----TETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGS 505

Query: 1510 VGQTTGAPTITSPSYSQHRAK-------SGSFYQLALLGSQIPEEALRVSSAPGPADQTT 1562
               T  + + T   +SQ           + +     L  + I +E+    S+   A  TT
Sbjct: 506  TETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSS-SDATGTT 564

Query: 1563 GIPTITSTSYSFGE------KPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPL 1616
             +P  ++ S   GE       P   Y   FP           S  SG TE+ T     P 
Sbjct: 565  PLPARSTASDLVGEPTTFYISPSPTYTTLFPAS---------SSTSGLTEESTTFHTSPS 615

Query: 1617 GSSAL 1621
             +S +
Sbjct: 616  FTSTI 620



 Score = 46.6 bits (109), Expect = 5e-04
 Identities = 93/444 (20%), Positives = 162/444 (36%), Gaps = 55/444 (12%)

Query: 478 AGDTSKGGIAKVTQSNLKSGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDT 537
           AG T++ G +   QS   S  TT    +   + +     +LS  +  SP  T T   + +
Sbjct: 156 AGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV-----ELSTTSHGSPSSTPTTHFSAS 210

Query: 538 LNQKTLADTHLTEETLKVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHL-- 595
                 ++   T  +  V     P+  ++ T  ++  S ++   P        P+S    
Sbjct: 211 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS 270

Query: 596 --TEEALKV--SAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSA 651
             +EE+     S    ++   +  S L     S+   PG+      PES+ T    E S 
Sbjct: 271 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEEST 330

Query: 652 APGPVEQKTGI---PTVSSTSHSHVEDLLFF---------YRQTLPDGHLTDQALKVSAV 699
           A        GI   P   +TS    E   F+            T     L+ ++  + + 
Sbjct: 331 ASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTTTTPGLSAKSTILYSS 390

Query: 700 SGPADQKTGTATVLSTPHSHREKPGIFYQQEFA-----DSHQTEETLTKVSAT----PGP 750
           S   DQ    A++ S+  S  E   ++ Q E        +  T   L++ S T    PG 
Sbjct: 391 SRSPDQTLSPASMTSSSIS-GEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGS 449

Query: 751 ADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSS 810
            +      ++ +SS++Q        P     S L       + V G +++ T   + P S
Sbjct: 450 TETTLSPGSITTSSFAQ----EFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGS 505

Query: 811 ----AYSHREKLLVFYQQA------------LLDSHLPEEAL-KVSAVSGPADGKTGTPA 853
               A+SH   + +  QQ+            +L + L    + + S     +   TGT  
Sbjct: 506 TETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTP 565

Query: 854 VTSTSSASSSLGEKPSAFYQQTLP 877
           + + S+AS  +GE P+ FY    P
Sbjct: 566 LPARSTASDLVGE-PTTFYISPSP 588


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 103/476 (21%), Positives = 169/476 (35%), Gaps = 81/476 (17%)

Query: 1031 STGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPAD----- 1085
            +T PG +++ T   +        R   + L P   + S + EES    + PG        
Sbjct: 10   TTTPGLSEKSTTFHS------SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 63

Query: 1086 QMTDTPAVPSTFYSQREKPGIFYQQTLPESHLP----KEALKISVAPGLADQKTGTPTVT 1141
              T TP +     +    PG      LP S       +E+     +PG  D      + T
Sbjct: 64   DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTT 123

Query: 1142 STSYSQH----REKPSIFHQQALP----GTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFY 1193
            + S+ Q        P   H    P     + I E + +V + TG  + +T +    ST  
Sbjct: 124  ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG--SPRTTLSPASST-- 179

Query: 1194 SQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQV 1253
                 PG+  + T   +H             PA   T TP+P S + +  E+   +++  
Sbjct: 180  ----SPGLQGESTAFQTH-------------PASTHT-TPSPPSTATAPVEESTTYHRS- 220

Query: 1254 LPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKN 1313
             P + PT                T  PA ++TS   + EK +IF+  S P +  T  +  
Sbjct: 221  -PGSTPT----------------THFPASSTTS--GHSEKSTIFH--SSPDASGTTPSSA 259

Query: 1314 VSAVPGPADQKTVIPILPST-----FYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPV 1368
             S   G +++ +     P +     F   T   G+  +    HS        +     P 
Sbjct: 260  HSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPP 319

Query: 1369 DQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPG-------PGDRKT- 1420
              T     V++T +S+ +  P+  +  S      +EE+  V + PG       PG   T 
Sbjct: 320  GTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGSTTTA 379

Query: 1421 GIPTLPSTFYSHTEKPGSFYQQV-LPHSHLPEEALEVSVAPGPVDQTIGTPTVTSP 1475
            G+    +TFYS    P +         S + EE+      PG    T    + T P
Sbjct: 380  GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 435



 Score = 50.8 bits (120), Expect = 3e-05
 Identities = 104/488 (21%), Positives = 172/488 (35%), Gaps = 107/488 (21%)

Query: 1125 SVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTW 1184
            +  PGL+++ T       T +S  R   +     +   + + EE+   ++ + PG+  T 
Sbjct: 10   TTTPGLSEKST-------TFHSSPRSPATTLSPASTTSSGVSEES--TTSHSRPGSTHT- 59

Query: 1185 IPRVLSTFYSQREKPGIFYQQTL----PGSHIPEEAQKVSPVLGPADQKT---------- 1230
                 + F      PG+    T     PGS         +   GP+ + T          
Sbjct: 60   -----TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD 114

Query: 1231 -----GTPTPTSASYSHT---EKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAV 1282
                 G+ T  S     T     PG  +  + PD+  +   ++   AS  V  +TG+P  
Sbjct: 115  TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE---ASTRVHSSTGSPRT 171

Query: 1283 T---STSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVP---------GPADQKTVIPIL 1330
            T   ++S S   +  S  +Q    S+H T    + +  P          P    T     
Sbjct: 172  TLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPA 231

Query: 1331 PSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPS 1390
             ST   H+EK  +F      HS P       S A      T+G    +STS+SQ     +
Sbjct: 232  SSTTSGHSEKSTIF------HSSPDASGTTPSSAHST---TSGVSEESSTSHSQPGSTHT 282

Query: 1391 IFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLP 1450
              +  S   S L++E    ++    G  +  + T PS        PG+            
Sbjct: 283  TAFPDSTTTSGLSQEP--TTSHSSQGSTEATLDTTPSP-------PGT------------ 321

Query: 1451 EEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPV 1510
                  + AP  V  T  +   ++P++ F      + +         EES  V  +PG  
Sbjct: 322  ------TAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRS--------EESTTVHSSPGST 367

Query: 1511 GQTTGAPTITSPS---------YSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQT 1561
             +TT  P  T+ +         YS  R+   +    +   S + EE+    S PG +  T
Sbjct: 368  -ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG-STHT 425

Query: 1562 TGIPTITS 1569
            T  P  T+
Sbjct: 426  TAFPGSTT 433



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 105/469 (22%), Positives = 159/469 (33%), Gaps = 67/469 (14%)

Query: 589  GLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLE 648
            GL +   T  +   S A  L+  +T  S ++  S +   +PG+ +    P+S  T     
Sbjct: 14   GLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTT----- 68

Query: 649  VSAAPGPVEQKTGIPTVSSTSHSH--VEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQ- 705
                        G+   S+TSHS     D       T   G   +     S+  G  D  
Sbjct: 69   -----------PGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS-PGSTDTA 116

Query: 706  -KTGTATVLS---TPHSHREKPGIFYQQEFADSHQTE---ETLTKVSATPGPADQKTEIP 758
               G+ T LS      +    PG  +   F DS  +    E  T+V ++ G + + T  P
Sbjct: 117  LSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG-SPRTTLSP 175

Query: 759  AVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKT-------GLPT----V 807
            A  +S   Q E  S  +    A +H        S    P ++ T         PT     
Sbjct: 176  ASSTSPGLQGE--STAFQTHPASTHTTPS--PPSTATAPVEESTTYHRSPGSTPTTHFPA 231

Query: 808  PSSAYSHREKLLVFYQQALLDSHLPEEA-LKVSAVSGPADGKTGTPAVTST-----SSAS 861
             S+   H EK  +F+         P  A    S VS  +      P  T T     S+ +
Sbjct: 232  SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTT 291

Query: 862  SSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQ 921
            S L ++P+  +     +   TE  L  +  P PG   T  P   S+ Y  R      +  
Sbjct: 292  SGLSQEPTTSHS----SQGSTEATLDTTPSP-PG--TTAAPVEVSTTYHSRPSSTPTTHF 344

Query: 922  TLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQ-ELPDSDLPRESL 980
            +             +  S   + +T     S+ +   SEKS+ FY     PD+ L   S 
Sbjct: 345  SASSTTLGRSEESTTVHSSPGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAST 404

Query: 981  KMSAI----------PGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWP 1019
              S +          PG T     P  T   G  S      I+Y  + P
Sbjct: 405  TSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGYHSIIPWSRIYYLPQRP 453



 Score = 41.6 bits (96), Expect = 0.017
 Identities = 86/411 (20%), Positives = 142/411 (34%), Gaps = 67/411 (16%)

Query: 1454 LEVSVAPGPVDQTIGTPTVTSPSSSFGEKP----IVIYKQAFPEGHLPEESLKVSVAPGP 1509
            +E +  PG       TP ++  S++F   P      +   +     + EES      PG 
Sbjct: 1    METTALPGSTT----TPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGS 56

Query: 1510 VGQTTGAPTITSPSYSQHRAKSGS--------FYQLALLGSQIPEEALRVSSAPGPADQT 1561
               T    + T+P  S+H   S S            +   S   +E+    S+PG  D  
Sbjct: 57   THTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD-- 114

Query: 1562 TGIPTITSTSYSFGEK-------PIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAG 1614
            T +   ++T+ SFG++       P   +   FPD          +  SG  E  T + + 
Sbjct: 115  TALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDS---------TTSSGIVEASTRVHSS 165

Query: 1615 PLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPV-HSTSY--SNRGK 1671
              GS      P +     L       +    S    P+   T T PV  ST+Y  S    
Sbjct: 166  -TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 224

Query: 1672 PVIFYQQTLSDSHLPEEAL---KVPPVPG--PDAQKTETPSVSSSLYSYREKPIVFYQQA 1726
            P   +  + + S   E++      P   G  P +  + T  VS    +   +P   +  A
Sbjct: 225  PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTA 284

Query: 1727 LPDSE----LTQE-----------ALKVSAVPQPADQKTGLSTVTSSFYSH-TEKPNISY 1770
             PDS     L+QE              +   P P         V+++++S  +  P   +
Sbjct: 285  FPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHF 344

Query: 1771 QQELPDSHLTEEALKVSNVPGPAD--------QKTGVSTVTSTSYSHREKP 1813
                     +EE+  V + PG  +           G+S  ++T YS    P
Sbjct: 345  SASSTTLGRSEESTTVHSSPGSTETTALPGSTTTAGLSEKSTTFYSSPRSP 395


>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
          Length = 2416

 Score = 57.4 bits (137), Expect = 3e-07
 Identities = 263/1145 (22%), Positives = 399/1145 (34%), Gaps = 249/1145 (21%)

Query: 515  LEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLK-VTAIPEPADQKTATPTVLS 573
            +ED+S L     LETT     D     +      T   ++ ++ +P     +TA P V  
Sbjct: 1046 VEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVED 1105

Query: 574  SSHSHRGK------PSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHRE 627
             S    G+      P +    GLP   + E     +AAPG+ D    +S L S       
Sbjct: 1106 ISGLPSGEVLETAAPGVEDISGLPSGEVLE-----TAAPGVED----ISGLPSGEVLETA 1156

Query: 628  KPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPT--VSSTSHSHVEDLLFFYRQTLP 685
             PG      LP   + E     +AAPG VE  +G+P+  V  T+   VED+       LP
Sbjct: 1157 APGVEDISGLPSGEVLE-----TAAPG-VEDISGLPSGEVLETAAPGVEDI-----SGLP 1205

Query: 686  DGHLTDQALK-VSAVSG-PADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEET--- 740
             G + + A   V  +SG P+ +   TA            PG+            E     
Sbjct: 1206 SGEVLETAAPGVEDISGLPSGEVLETAA-----------PGVEDISGLPSGEVLETAAPG 1254

Query: 741  LTKVSATPGPADQKTEIPAVQS-SSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPAD 799
            +  +S  P     +T  P V+  S     E      P     S LP  G  +   A   D
Sbjct: 1255 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS-GEVLETTAPGVD 1313

Query: 800  QKTGLPT---VPSSAYSHRE-------KLLVFYQQALLD-SHLPE--EALKVSA-----V 841
            + +GLP+   + ++A    E       ++L     A+ D S LP   E L++S      +
Sbjct: 1314 EISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDI 1373

Query: 842  SGPADGK---TGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQK 898
            SG   G+   T    +   S   S  G + SA   + L      EE L++S   G GD  
Sbjct: 1374 SGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEIS-ASGFGDL- 1431

Query: 899  TGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSH 958
            +G+PS                           E L+ SA  V      GT      S   
Sbjct: 1432 SGLPSGG-------------------------EGLETSASEV------GTDLSGLPSGRE 1460

Query: 959  SEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEW 1018
              ++S    ++L      +E L  SA   L   K      +PSG+    + P        
Sbjct: 1461 GLETSASGAEDLSGLPSGKEDLVGSASGDLDLGK------LPSGTLGSGQAPET---SGL 1511

Query: 1019 PDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQV-LSDSHLPEESLKV 1077
            P  ++ E +  V  G GP     +   + S            +P V L DS L E     
Sbjct: 1512 PSGFSGEYS-GVDLGSGPPSGLPDFSGLPSG-----------FPTVSLVDSTLVE----- 1554

Query: 1078 SAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPE-SHLPKEALKISVAPG------- 1129
                           V ++  S+ E  G        E S LP   L IS           
Sbjct: 1555 --------------VVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTE 1600

Query: 1130 LADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVL 1189
            L+ Q +G+P V+        E P +F     P +  P+ + + S VT      +  P + 
Sbjct: 1601 LSGQASGSPDVSG-------EIPGLFGVSGQP-SGFPDTSGETSGVTELSGLSSGQPGIS 1652

Query: 1190 STFYSQREKPGIFYQQTLP---------GSHIPEEAQKVSPVLGPADQKTGTPTPTSASY 1240
                   E  G+ Y  + P          S +P+ + + S + G +   +G P   S + 
Sbjct: 1653 G------EASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTT 1706

Query: 1241 SHT-EKPGIFYQ-----QVLPDNHPTEEAL-KISVASEPVDQT--TGTPAVTSTSYSQYR 1291
            S + E  GI +      +V P     EE L  + ++  P  +   +G   +   S     
Sbjct: 1707 SGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQ--- 1763

Query: 1292 EKPSIFYQQSLPSSHLTEEAKNVSAVP-------GPADQKTVIPILPSTFYSHTEKPGVF 1344
                  +  ++ SS  T +    S +P       G + +  +   LPS         G +
Sbjct: 1764 ------FSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPS---------GAY 1808

Query: 1345 YQQVLPHSHPT----EEALKISVASEPVDQTTGT-PTVTSTSYSQHTEKPSIFYQQSLPG 1399
            Y    P S PT    +  L  SV   P  Q  G  P+        H+  P +  + S   
Sbjct: 1809 YGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHS--- 1865

Query: 1400 SHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVA 1459
                + +   S +  P     G P     F S T   G                 E SVA
Sbjct: 1866 -GFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSG-----------------ESSVA 1907

Query: 1460 PGPVDQTIGTPTVTSPSSSFGE---KPIVIYK--QAFPEGHLP---EESLKVSVAPGPVG 1511
             G   +  G P VT  +S F E   +P +  +  Q  P  H P   E S KVS A    G
Sbjct: 1908 MGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTA----G 1963

Query: 1512 QTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTS 1571
              +GA  +   S      +  S  + +   S  PE     S+AP  + + +G P ++ T+
Sbjct: 1964 DISGATPVLPGS----GVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETT 2019

Query: 1572 YSFGE 1576
             +F E
Sbjct: 2020 SAFHE 2024



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 233/1057 (22%), Positives = 363/1057 (34%), Gaps = 205/1057 (19%)

Query: 555  VTAIPEPADQKTATPTVLSSSHSHRGK------PSIFYQQGLPDSHLTEEALKVSAAPGL 608
            ++ +P     +TA P V   S    G+      P +    GLP   + E     +AAPG+
Sbjct: 1220 ISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLE-----TAAPGV 1274

Query: 609  ADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPT--VS 666
             D    +S L S        PG      LP   + E     + APG V++ +G+P+  V 
Sbjct: 1275 ED----ISGLPSGEVLETTAPGVEEISGLPSGEVLE-----TTAPG-VDEISGLPSGEVL 1324

Query: 667  STSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIF 726
             T+   VE++       LP G + + +   SAV   +   +G   VL    S  E     
Sbjct: 1325 ETTAPGVEEI-----SGLPSGEVLETS--TSAVGDLSGLPSG-GEVLEISVSGVEDISGL 1376

Query: 727  YQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQS-SSYSQREKPSILYPQDLAD-SHL 784
               E  ++  +   +  VS  P     +T    V+  S     E+   +      D S L
Sbjct: 1377 PSGEVVET--SASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGL 1434

Query: 785  PE--EGLKVSA------VAGPADQKTGLPTVPSSAY------SHREKLLVFYQQALLDSH 830
            P   EGL+ SA      ++G    + GL T  S A       S +E L+      L    
Sbjct: 1435 PSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGK 1494

Query: 831  LPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKP-----------SAFYQQTLPNS 879
            LP   L     SG A   +G P+  S   +   LG  P           S F   +L +S
Sbjct: 1495 LPSGTLG----SGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDS 1550

Query: 880  HLTE----------EALKVSIVPGPGD-------------QKTGIPS-------APSSFY 909
             L E          E      + G G+             + +G+PS       A  S  
Sbjct: 1551 TLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPD 1610

Query: 910  SHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQE 969
               E P +F     P   FP+ + + S V+ L+   +G P +S       E S V Y   
Sbjct: 1611 VSGEIPGLFGVSGQPSG-FPDTSGETSGVTELSGLSSGQPGISG------EASGVLYGTS 1663

Query: 970  LP---------DSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPS------IFY 1014
             P          S +P  S + S +PG +   T   P + SG+ S   + S         
Sbjct: 1664 QPFGITDLSGETSGVPDLSGQPSGLPGFSGA-TSGVPDLVSGTTSGSGESSGITFVDTSL 1722

Query: 1015 QQEWPDSYATEKAL---KVSTGP-GPADQKTEIPAVQ-SSSYPQREKPSVLYPQVLSDSH 1069
             +  P ++  E+ L   ++S  P G AD   +   V  S  +      S    Q    S 
Sbjct: 1723 VEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSG 1782

Query: 1070 LPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIF-----YQQTLPESHL------- 1117
            LP    +VS   G + +     ++PS  Y     P  F       +TL ES         
Sbjct: 1783 LPSGIAEVS---GESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQE 1839

Query: 1118 ----PKEALKISVAPGLADQKTGTPT-------VTSTSYSQHREKPSI--FHQQALPGTH 1164
                P   L++S A   A   +G  +       + S       E P    F       T+
Sbjct: 1840 AGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTN 1899

Query: 1165 IPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQ--QTLPGSHIPEEAQKVSPV 1222
            +  E+      +G  +    +  + S F     +P I  +  Q  P +H P+  +    V
Sbjct: 1900 VSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKV 1959

Query: 1223 LGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAV 1282
                D    TP    +    +  P    +     +   E     S A E   + +G+P +
Sbjct: 1960 STAGDISGATPVLPGSGVEVSSVP----ESSSETSAYPEAGFGASAAPEASREDSGSPDL 2015

Query: 1283 TSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPG 1342
            + T+ + +           +  S LT +    SA P  + + T      +T    TE PG
Sbjct: 2016 SETTSAFHEANLERSSGLGVSGSTLTFQEGEASAAPEVSGEST------TTSDVGTEAPG 2069

Query: 1343 VFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHL 1402
                  LP + PT                +G  T  S   S HT +  +    S+P S  
Sbjct: 2070 ------LPSATPT---------------ASGDRTEISGDLSGHTSQLGVVISTSIPESEW 2108

Query: 1403 TEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEA---LEVSVA 1459
            T++ +       P +    I +  S  YS  E            +H  E A    + S+ 
Sbjct: 2109 TQQTQR------PAETHLEIES-SSLLYSGEE------------THTVETATSPTDASIP 2149

Query: 1460 PGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHL 1496
              P  +     T  +P+ S  E+P         EGH+
Sbjct: 2150 ASPEWKRESESTAAAPARSCAEEPCGAGTCKETEGHV 2186


>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
          Length = 2317

 Score = 57.4 bits (137), Expect = 3e-07
 Identities = 263/1145 (22%), Positives = 399/1145 (34%), Gaps = 249/1145 (21%)

Query: 515  LEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHLTEETLK-VTAIPEPADQKTATPTVLS 573
            +ED+S L     LETT     D     +      T   ++ ++ +P     +TA P V  
Sbjct: 1046 VEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVED 1105

Query: 574  SSHSHRGK------PSIFYQQGLPDSHLTEEALKVSAAPGLADQTTGMSTLTSTSYSHRE 627
             S    G+      P +    GLP   + E     +AAPG+ D    +S L S       
Sbjct: 1106 ISGLPSGEVLETAAPGVEDISGLPSGEVLE-----TAAPGVED----ISGLPSGEVLETA 1156

Query: 628  KPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPT--VSSTSHSHVEDLLFFYRQTLP 685
             PG      LP   + E     +AAPG VE  +G+P+  V  T+   VED+       LP
Sbjct: 1157 APGVEDISGLPSGEVLE-----TAAPG-VEDISGLPSGEVLETAAPGVEDI-----SGLP 1205

Query: 686  DGHLTDQALK-VSAVSG-PADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEET--- 740
             G + + A   V  +SG P+ +   TA            PG+            E     
Sbjct: 1206 SGEVLETAAPGVEDISGLPSGEVLETAA-----------PGVEDISGLPSGEVLETAAPG 1254

Query: 741  LTKVSATPGPADQKTEIPAVQS-SSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPAD 799
            +  +S  P     +T  P V+  S     E      P     S LP  G  +   A   D
Sbjct: 1255 VEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPS-GEVLETTAPGVD 1313

Query: 800  QKTGLPT---VPSSAYSHRE-------KLLVFYQQALLD-SHLPE--EALKVSA-----V 841
            + +GLP+   + ++A    E       ++L     A+ D S LP   E L++S      +
Sbjct: 1314 EISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDI 1373

Query: 842  SGPADGK---TGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQK 898
            SG   G+   T    +   S   S  G + SA   + L      EE L++S   G GD  
Sbjct: 1374 SGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEIS-ASGFGDL- 1431

Query: 899  TGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSH 958
            +G+PS                           E L+ SA  V      GT      S   
Sbjct: 1432 SGLPSGG-------------------------EGLETSASEV------GTDLSGLPSGRE 1460

Query: 959  SEKSSVFYQQELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEW 1018
              ++S    ++L      +E L  SA   L   K      +PSG+    + P        
Sbjct: 1461 GLETSASGAEDLSGLPSGKEDLVGSASGDLDLGK------LPSGTLGSGQAPET---SGL 1511

Query: 1019 PDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQV-LSDSHLPEESLKV 1077
            P  ++ E +  V  G GP     +   + S            +P V L DS L E     
Sbjct: 1512 PSGFSGEYS-GVDLGSGPPSGLPDFSGLPSG-----------FPTVSLVDSTLVE----- 1554

Query: 1078 SAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPE-SHLPKEALKISVAPG------- 1129
                           V ++  S+ E  G        E S LP   L IS           
Sbjct: 1555 --------------VVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTE 1600

Query: 1130 LADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVL 1189
            L+ Q +G+P V+        E P +F     P +  P+ + + S VT      +  P + 
Sbjct: 1601 LSGQASGSPDVSG-------EIPGLFGVSGQP-SGFPDTSGETSGVTELSGLSSGQPGIS 1652

Query: 1190 STFYSQREKPGIFYQQTLP---------GSHIPEEAQKVSPVLGPADQKTGTPTPTSASY 1240
                   E  G+ Y  + P          S +P+ + + S + G +   +G P   S + 
Sbjct: 1653 G------EASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTT 1706

Query: 1241 SHT-EKPGIFYQ-----QVLPDNHPTEEAL-KISVASEPVDQT--TGTPAVTSTSYSQYR 1291
            S + E  GI +      +V P     EE L  + ++  P  +   +G   +   S     
Sbjct: 1707 SGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQ--- 1763

Query: 1292 EKPSIFYQQSLPSSHLTEEAKNVSAVP-------GPADQKTVIPILPSTFYSHTEKPGVF 1344
                  +  ++ SS  T +    S +P       G + +  +   LPS         G +
Sbjct: 1764 ------FSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPS---------GAY 1808

Query: 1345 YQQVLPHSHPT----EEALKISVASEPVDQTTGT-PTVTSTSYSQHTEKPSIFYQQSLPG 1399
            Y    P S PT    +  L  SV   P  Q  G  P+        H+  P +  + S   
Sbjct: 1809 YGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHS--- 1865

Query: 1400 SHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVA 1459
                + +   S +  P     G P     F S T   G                 E SVA
Sbjct: 1866 -GFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSG-----------------ESSVA 1907

Query: 1460 PGPVDQTIGTPTVTSPSSSFGE---KPIVIYK--QAFPEGHLP---EESLKVSVAPGPVG 1511
             G   +  G P VT  +S F E   +P +  +  Q  P  H P   E S KVS A    G
Sbjct: 1908 MGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTA----G 1963

Query: 1512 QTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTS 1571
              +GA  +   S      +  S  + +   S  PE     S+AP  + + +G P ++ T+
Sbjct: 1964 DISGATPVLPGS----GVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETT 2019

Query: 1572 YSFGE 1576
             +F E
Sbjct: 2020 SAFHE 2024



 Score = 38.5 bits (88), Expect = 0.14
 Identities = 58/268 (21%), Positives = 93/268 (34%), Gaps = 42/268 (15%)

Query: 616  STLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVED 675
            S+L S +Y     P +F    L +  L E   +   A    E  +GI  +S  +HS   D
Sbjct: 1801 SSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSG-AHSGAPD 1859

Query: 676  LLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSH 735
            +   +      G L    L+ S +  P+ +  GT                ++  +FA + 
Sbjct: 1860 MSGEH-----SGFLDLSGLQ-SGLIEPSGEPPGTP---------------YFSGDFASTT 1898

Query: 736  QTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLAD----SHLPEEGLKV 791
                  +    T G A    E+  + S       +P+I   Q+L      +H P+     
Sbjct: 1899 NVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTI--SQELGQRPPVTHTPQLFESS 1956

Query: 792  SAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGT 851
              V+   D     P +P S                  S +PE + + SA      G +  
Sbjct: 1957 GKVSTAGDISGATPVLPGSGVEV--------------SSVPESSSETSAYPEAGFGASAA 2002

Query: 852  PAVTSTSSASSSLGEKPSAFYQQTLPNS 879
            P  +   S S  L E  SAF++  L  S
Sbjct: 2003 PEASREDSGSPDLSETTSAFHEANLERS 2030


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 40/102 (39%), Positives = 47/102 (46%), Gaps = 18/102 (17%)

Query: 11  ELEEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSDSHYGPQHLESID 70
           E EEEEEEEEEEEEEEEEE         D+    EE EEE   E + +       LE  +
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEE-EEEEEEEFEEEFEEEEGELEEEE 946

Query: 71  DEEDEEAKAWLQ-----------------AHPGRILPPLSPP 95
           +EEDEE +  L+                 A P   LPP  PP
Sbjct: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPP 988


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 54.7 bits (130), Expect = 2e-06
 Identities = 202/884 (22%), Positives = 313/884 (35%), Gaps = 135/884 (15%)

Query: 1055 EKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPG-----IFYQ 1109
            E PS+   Q L  SH P++S +      PA           TF S+++ PG     I  +
Sbjct: 77   ESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLK 136

Query: 1110 QTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEA 1169
            ++   + L KE  K S+ PG   +      V+S   ++      I   +A       EE 
Sbjct: 137  ESKSRTDL-KEEHKSSMMPGFLSEVNALSAVSSV-VNKFNPFDLISDSEA-----SQEET 189

Query: 1170 QKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQK 1229
             K   V      K   P  +     Q++ P    +Q  PG           P+     Q+
Sbjct: 190  TKKQKVVQKEQGK---PEGIIKPPLQQQPPKPIPKQQGPGR---------DPL-----QQ 232

Query: 1230 TGTPTPTSASYSH---TEKPGIFYQQVLPDNHPTEEALKISV---ASEPVDQTTGTPAVT 1283
             GTP   S+       ++ PG       P   P  +  K+ +   AS P  QT     V 
Sbjct: 233  DGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP--QTKQADIVR 290

Query: 1284 STSYSQYREKPS-IFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSH-TEKP 1341
              S       PS    QQ  P     ++  +  + PGPA      P  PS       ++P
Sbjct: 291  GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP----PAQPSGLTKPLAQQP 346

Query: 1342 GVFYQQVLPHSHPTEEALKISVASEPVDQT-TGTPTVTSTSYSQHTEKPSIF---YQQSL 1397
            G     V P       A  +  A  P  QT +  P+          + P +     QQ  
Sbjct: 347  GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG 406

Query: 1398 PGSHLTEEA---KNVSAVPG-------PGDRKTGIPTL-PSTFYSHTEKPGSFYQQ---- 1442
            P    T++    K ++  PG       PG  KT +    P    +    PG    Q    
Sbjct: 407  PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466

Query: 1443 VLPHSHLPEEALEVSVAPGPV---DQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEE 1499
              P S LP  A      PGP     Q  G+    S      + P      A P    P  
Sbjct: 467  TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526

Query: 1500 SLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVS-SAPGPA 1558
            +   S  PG    +   P+   PS  Q      S   ++  GS  P +   VS SA  P 
Sbjct: 527  TKPPSQQPGSAKPSAQQPSPAKPSAQQ------STKPVSQTGSGKPLQPPTVSPSAKQPP 580

Query: 1559 DQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGS 1618
             Q  G+P            P+ N  +     H+PE+A      +  TE +T +       
Sbjct: 581  SQ--GLPKTIC--------PLCNTTELLL--HVPEKA----NFNTCTECQTTV------C 618

Query: 1619 SALGEKP---ITFYRQALLDSPLNKEVVKVSAAPGPA--DQKTETLPVHSTSYSNRGKPV 1673
            S  G  P   +T  ++ L  +   K  +    AP P+    K +T PV +TS  ++  P 
Sbjct: 619  SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ 678

Query: 1674 ---------IFYQQTLSDSHLPEE---ALKVPPVPGPDAQKTETPSVSSSLYSYREKPIV 1721
                        +Q LS +  P++    +K P + G  + K + P  + SL     KP  
Sbjct: 679  PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL----SKPAP 734

Query: 1722 FYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTE 1781
              + ++P SE  +  +      QP   K     V+SS  S T KP+I      P S +  
Sbjct: 735  PKEPSVP-SEQDKAPVADDKPKQPKMVKPTTDLVSSS--SATTKPDI------PSSKVQS 785

Query: 1782 EALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQK 1841
            +A + +  P   D     S   S S+    + +  +  +      +  KI+  PGP+ + 
Sbjct: 786  QAEEKTTPPLKTD-----SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840

Query: 1842 TG---INILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGP 1882
             G   ++ +     P++  + +S +   PD   +   +   PGP
Sbjct: 841  KGQKQVDPVQKKEEPKKAQTKMSPK---PDAKPMPKGSPTPPGP 881


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 54.7 bits (130), Expect = 2e-06
 Identities = 202/884 (22%), Positives = 313/884 (35%), Gaps = 135/884 (15%)

Query: 1055 EKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPG-----IFYQ 1109
            E PS+   Q L  SH P++S +      PA           TF S+++ PG     I  +
Sbjct: 77   ESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLK 136

Query: 1110 QTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEA 1169
            ++   + L KE  K S+ PG   +      V+S   ++      I   +A       EE 
Sbjct: 137  ESKSRTDL-KEEHKSSMMPGFLSEVNALSAVSSV-VNKFNPFDLISDSEA-----SQEET 189

Query: 1170 QKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQK 1229
             K   V      K   P  +     Q++ P    +Q  PG           P+     Q+
Sbjct: 190  TKKQKVVQKEQGK---PEGIIKPPLQQQPPKPIPKQQGPGR---------DPL-----QQ 232

Query: 1230 TGTPTPTSASYSH---TEKPGIFYQQVLPDNHPTEEALKISV---ASEPVDQTTGTPAVT 1283
             GTP   S+       ++ PG       P   P  +  K+ +   AS P  QT     V 
Sbjct: 233  DGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP--QTKQADIVR 290

Query: 1284 STSYSQYREKPS-IFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSH-TEKP 1341
              S       PS    QQ  P     ++  +  + PGPA      P  PS       ++P
Sbjct: 291  GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP----PAQPSGLTKPLAQQP 346

Query: 1342 GVFYQQVLPHSHPTEEALKISVASEPVDQT-TGTPTVTSTSYSQHTEKPSIF---YQQSL 1397
            G     V P       A  +  A  P  QT +  P+          + P +     QQ  
Sbjct: 347  GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG 406

Query: 1398 PGSHLTEEA---KNVSAVPG-------PGDRKTGIPTL-PSTFYSHTEKPGSFYQQ---- 1442
            P    T++    K ++  PG       PG  KT +    P    +    PG    Q    
Sbjct: 407  PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466

Query: 1443 VLPHSHLPEEALEVSVAPGPV---DQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEE 1499
              P S LP  A      PGP     Q  G+    S      + P      A P    P  
Sbjct: 467  TKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526

Query: 1500 SLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVS-SAPGPA 1558
            +   S  PG    +   P+   PS  Q      S   ++  GS  P +   VS SA  P 
Sbjct: 527  TKPPSQQPGSAKPSAQQPSPAKPSAQQ------STKPVSQTGSGKPLQPPTVSPSAKQPP 580

Query: 1559 DQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGS 1618
             Q  G+P            P+ N  +     H+PE+A      +  TE +T +       
Sbjct: 581  SQ--GLPKTIC--------PLCNTTELLL--HVPEKA----NFNTCTECQTTV------C 618

Query: 1619 SALGEKP---ITFYRQALLDSPLNKEVVKVSAAPGPA--DQKTETLPVHSTSYSNRGKPV 1673
            S  G  P   +T  ++ L  +   K  +    AP P+    K +T PV +TS  ++  P 
Sbjct: 619  SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ 678

Query: 1674 ---------IFYQQTLSDSHLPEE---ALKVPPVPGPDAQKTETPSVSSSLYSYREKPIV 1721
                        +Q LS +  P++    +K P + G  + K + P  + SL     KP  
Sbjct: 679  PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSL----SKPAP 734

Query: 1722 FYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTE 1781
              + ++P SE  +  +      QP   K     V+SS  S T KP+I      P S +  
Sbjct: 735  PKEPSVP-SEQDKAPVADDKPKQPKMVKPTTDLVSSS--SATTKPDI------PSSKVQS 785

Query: 1782 EALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQK 1841
            +A + +  P   D     S   S S+    + +  +  +      +  KI+  PGP+ + 
Sbjct: 786  QAEEKTTPPLKTD-----SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840

Query: 1842 TG---INILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGP 1882
             G   ++ +     P++  + +S +   PD   +   +   PGP
Sbjct: 841  KGQKQVDPVQKKEEPKKAQTKMSPK---PDAKPMPKGSPTPPGP 881


>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 53.1 bits (126), Expect = 6e-06
 Identities = 104/490 (21%), Positives = 183/490 (37%), Gaps = 51/490 (10%)

Query: 1449 LPEEALEVSVAPGPVDQTIGTPTVTSPSS---------SFGEKPI----VIYKQAFPEGH 1495
            L +E++     P P ++T  T    SP +           G KP+    ++ +QA  +  
Sbjct: 536  LGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAEEDLT 595

Query: 1496 LPEESLKVSVAPGPVGQTTGAPT-ITSPSYSQHRAKSG-SFYQLALLGSQIPEEALRVSS 1553
            LP++S      P      + AP  + + +    +A+ G +  Q +++   +P +   +SS
Sbjct: 596  LPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSS 655

Query: 1554 APGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHL---PEEALKVSIVSGPTEKKTD 1610
            AP P    T +        +  +   +       D  L   P+     ++VS   E+   
Sbjct: 656  APKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLT 715

Query: 1611 IPAG-------PLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQK-TETLPVH 1662
            +P         PL  + L   P       L+     + +        P D   T  LP+ 
Sbjct: 716  LPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTL------PQDSAMTPPLPLQ 769

Query: 1663 STSYSNRGKPV----IFYQQTLSDSHLPEEALKVPPVPGPDAQKTETPS--VSSSLYSYR 1716
             T  S+  KPV    I  QQ      LP+++   PP+P  D   +  P    +++L S +
Sbjct: 770  DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQ 829

Query: 1717 -EKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELP 1775
             E+ +   Q +     L  +   +S+ P+P    T +S       +  +   ++    L 
Sbjct: 830  AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQ 889

Query: 1776 DSHLTE--EALKVSNVPGPADQKTGVSTVTS--TSYSHREKPIVSYQRELPHFTEAGLKI 1831
            D+  T   E L V+  P     + G +  T    + + +E       R  P    A L  
Sbjct: 890  DTGPTSGPEPLAVA-TPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPT 948

Query: 1832 LRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQI 1891
            +  P   DQ     +   +  P  E       QE  D T + ++A+ +P PA    G +I
Sbjct: 949  VPEPAALDQ-----VQQDDPQPAAEAGTPWAAQEDADST-LGMEALSLPEPA-SGAGEEI 1001

Query: 1892 ASSSSYSNRE 1901
            A + S   RE
Sbjct: 1002 AEALSRPGRE 1011



 Score = 36.6 bits (83), Expect = 0.54
 Identities = 98/512 (19%), Positives = 183/512 (35%), Gaps = 84/512 (16%)

Query: 1034 PGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAV 1093
            P   +++T+  A Q S+     +PS    Q      L +ES+     P P ++ T     
Sbjct: 504  PQAGEEETDSTAGQESAAMAMPQPS----QEGISEILGQESVTAEKLPTPQEE-TSLTLC 558

Query: 1094 PSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTS----------- 1142
            P +  + +E+ G+     LP    P  A   ++ P  A++    P  ++           
Sbjct: 559  PDSPQNLKEEGGL----DLPSGRKPVAAA--TIVPRQAEEDLTLPQDSAMTPPLPLQDTD 612

Query: 1143 -TSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKP-- 1199
             +S  +     +I  QQA  G  +P++    S +T P      +P +  T  S   KP  
Sbjct: 613  LSSAPKPVAAATIVSQQAEEGLTLPQD----SVMTPP------LP-LQDTELSSAPKPVA 661

Query: 1200 --GIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSAS--YSHTEKPGIFYQQVLP 1255
               +  QQ   G  +P+++    P+       +  P P +A+   S   + G+       
Sbjct: 662  AATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTL----- 716

Query: 1256 DNHPTEEALKISVASEPVDQTTGT-PAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNV 1314
               P + A+   +  +  D ++   P   +T  SQ  E+     Q S  +  L  +  ++
Sbjct: 717  ---PQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDL 773

Query: 1315 SAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTG- 1373
            S+ P P    T++        S   + G+        + P + A+   +  +  D ++  
Sbjct: 774  SSAPKPVAAATIV--------SQQAEEGL--------TLPQDSAMTPPLPLQDTDLSSAP 817

Query: 1374 TPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHT 1433
             P   +T  SQ  E+     Q S     L  +  ++S+ P P    T +           
Sbjct: 818  KPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVS-------QQA 870

Query: 1434 EKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSF--GEKPIVIYKQAF 1491
            E+  +  Q     + LP +  +     GP    + TP      +    G +P+    Q  
Sbjct: 871  EEGLTLPQDSAMTAPLPLQ--DTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQ-- 926

Query: 1492 PEGHLPEESLKVSVAPGPVGQTTGAPTITSPS 1523
                  E    +   P P  +    PT+  P+
Sbjct: 927  -----QEVGEALGPRPAPEEKNAALPTVPEPA 953


>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 52.8 bits (125), Expect = 7e-06
 Identities = 102/490 (20%), Positives = 181/490 (36%), Gaps = 51/490 (10%)

Query: 1449 LPEEALEVSVAPGPVDQTIGTPTVTSPSS---------SFGEKPI----VIYKQAFPEGH 1495
            L +E++     P P ++T  T    SP +           G KP+    ++ +QA  +  
Sbjct: 536  LGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLT 595

Query: 1496 LPEESLKVSVAPGPVGQTTGAPT-ITSPSYSQHRAKSG-SFYQLALLGSQIPEEALRVSS 1553
            LP++S      P      + AP  + + +    +A+ G +  Q +++   +P +   +SS
Sbjct: 596  LPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSS 655

Query: 1554 APGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHL---PEEALKVSIVSGPTEKKTD 1610
            AP P    T +        +  +   +       D  L   P+     ++VS   E+   
Sbjct: 656  APKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLT 715

Query: 1611 IPAG-------PLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQK-TETLPVH 1662
            +P         PL  + L   P       L+     + +        P D   T  LP+ 
Sbjct: 716  LPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTL------PQDSAMTPPLPLQ 769

Query: 1663 STSYSNRGKPV----IFYQQTLSDSHLPEEALKVPPVPGPDAQKTETP---SVSSSLYSY 1715
             T  S+  KPV    I  QQ      LP+++   PP+P  D   +  P   + ++ +   
Sbjct: 770  DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 829

Query: 1716 REKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELP 1775
             E+ +   Q +     L  +   +S+ P+P    T +S       +  +   ++    L 
Sbjct: 830  AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQ 889

Query: 1776 DSHLTE--EALKVSNVPGPADQKTGVSTVTS--TSYSHREKPIVSYQRELPHFTEAGLKI 1831
            D+  T   E L V+  P     + G +  T    + + +E       R  P    A L  
Sbjct: 890  DTGPTSGPEPLAVA-TPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPT 948

Query: 1832 LRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQI 1891
            +  P   DQ     +   +  P  E       QE  D T + ++A+ +P PA    G +I
Sbjct: 949  VPEPAALDQ-----VQQDDPQPAAEAGTPWAAQEDADST-LGMEALSLPEPA-SGAGEEI 1001

Query: 1892 ASSSSYSNRE 1901
            A + S   RE
Sbjct: 1002 AEALSRPGRE 1011



 Score = 35.8 bits (81), Expect = 0.91
 Identities = 95/516 (18%), Positives = 176/516 (34%), Gaps = 92/516 (17%)

Query: 1034 PGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAV 1093
            P   +++T+  A Q S+     +PS    Q      L +ES+     P P ++ T     
Sbjct: 504  PQAGEEETDSTAGQESAAMAMPQPS----QEGISEILGQESVTAEKLPTPQEE-TSLTLC 558

Query: 1094 PSTFYSQREKPGIFYQQTLPESHLPKEALKI---------------SVAPGLADQKTGT- 1137
            P +  + +E+ G+     LP    P  A  I               ++ P L  Q T   
Sbjct: 559  PDSPQNLKEEGGL----DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLS 614

Query: 1138 ----PTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFY 1193
                P   +T  SQ  E+     Q ++    +P +  ++S+   P    T +        
Sbjct: 615  SAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVS------- 667

Query: 1194 SQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSAS--YSHTEKPGIFYQ 1251
                      QQ   G  +P+++    P+       +  P P +A+   S   + G+   
Sbjct: 668  ----------QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTL- 716

Query: 1252 QVLPDNHPTEEALKISVASEPVDQTTGT-PAVTSTSYSQYREKPSIFYQQSLPSSHLTEE 1310
                   P + A+   +  +  D ++   P   +T  SQ  E+     Q S  +  L  +
Sbjct: 717  -------PQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 769

Query: 1311 AKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQ 1370
              ++S+ P P    T++        S   + G+        + P + A+   +  +  D 
Sbjct: 770  DTDLSSAPKPVAAATIV--------SQQAEEGL--------TLPQDSAMTPPLPLQDTDL 813

Query: 1371 TTG-TPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTF 1429
            ++   P   +T  SQ  E+     Q S     L  +  ++S+ P P    T +       
Sbjct: 814  SSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVS------ 867

Query: 1430 YSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSF--GEKPIVIY 1487
                E+  +  Q     + LP +  +     GP    + TP      +    G +P+   
Sbjct: 868  -QQAEEGLTLPQDSAMTAPLPLQ--DTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATM 924

Query: 1488 KQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPS 1523
             Q        E    +   P P  +    PT+  P+
Sbjct: 925  AQ-------QEVGEALGPRPAPEEKNAALPTVPEPA 953


>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 52.8 bits (125), Expect = 7e-06
 Identities = 102/490 (20%), Positives = 181/490 (36%), Gaps = 51/490 (10%)

Query: 1449 LPEEALEVSVAPGPVDQTIGTPTVTSPSS---------SFGEKPI----VIYKQAFPEGH 1495
            L +E++     P P ++T  T    SP +           G KP+    ++ +QA  +  
Sbjct: 536  LGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLT 595

Query: 1496 LPEESLKVSVAPGPVGQTTGAPT-ITSPSYSQHRAKSG-SFYQLALLGSQIPEEALRVSS 1553
            LP++S      P      + AP  + + +    +A+ G +  Q +++   +P +   +SS
Sbjct: 596  LPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSS 655

Query: 1554 APGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHL---PEEALKVSIVSGPTEKKTD 1610
            AP P    T +        +  +   +       D  L   P+     ++VS   E+   
Sbjct: 656  APKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLT 715

Query: 1611 IPAG-------PLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQK-TETLPVH 1662
            +P         PL  + L   P       L+     + +        P D   T  LP+ 
Sbjct: 716  LPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTL------PQDSAMTPPLPLQ 769

Query: 1663 STSYSNRGKPV----IFYQQTLSDSHLPEEALKVPPVPGPDAQKTETP---SVSSSLYSY 1715
             T  S+  KPV    I  QQ      LP+++   PP+P  D   +  P   + ++ +   
Sbjct: 770  DTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQ 829

Query: 1716 REKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELP 1775
             E+ +   Q +     L  +   +S+ P+P    T +S       +  +   ++    L 
Sbjct: 830  AEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQ 889

Query: 1776 DSHLTE--EALKVSNVPGPADQKTGVSTVTS--TSYSHREKPIVSYQRELPHFTEAGLKI 1831
            D+  T   E L V+  P     + G +  T    + + +E       R  P    A L  
Sbjct: 890  DTGPTSGPEPLAVA-TPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPT 948

Query: 1832 LRVPGPADQKTGINILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQI 1891
            +  P   DQ     +   +  P  E       QE  D T + ++A+ +P PA    G +I
Sbjct: 949  VPEPAALDQ-----VQQDDPQPAAEAGTPWAAQEDADST-LGMEALSLPEPA-SGAGEEI 1001

Query: 1892 ASSSSYSNRE 1901
            A + S   RE
Sbjct: 1002 AEALSRPGRE 1011



 Score = 35.8 bits (81), Expect = 0.91
 Identities = 95/516 (18%), Positives = 176/516 (34%), Gaps = 92/516 (17%)

Query: 1034 PGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAV 1093
            P   +++T+  A Q S+     +PS    Q      L +ES+     P P ++ T     
Sbjct: 504  PQAGEEETDSTAGQESAAMAMPQPS----QEGISEILGQESVTAEKLPTPQEE-TSLTLC 558

Query: 1094 PSTFYSQREKPGIFYQQTLPESHLPKEALKI---------------SVAPGLADQKTGT- 1137
            P +  + +E+ G+     LP    P  A  I               ++ P L  Q T   
Sbjct: 559  PDSPQNLKEEGGL----DLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLS 614

Query: 1138 ----PTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFY 1193
                P   +T  SQ  E+     Q ++    +P +  ++S+   P    T +        
Sbjct: 615  SAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVS------- 667

Query: 1194 SQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSAS--YSHTEKPGIFYQ 1251
                      QQ   G  +P+++    P+       +  P P +A+   S   + G+   
Sbjct: 668  ----------QQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTL- 716

Query: 1252 QVLPDNHPTEEALKISVASEPVDQTTGT-PAVTSTSYSQYREKPSIFYQQSLPSSHLTEE 1310
                   P + A+   +  +  D ++   P   +T  SQ  E+     Q S  +  L  +
Sbjct: 717  -------PQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQ 769

Query: 1311 AKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQ 1370
              ++S+ P P    T++        S   + G+        + P + A+   +  +  D 
Sbjct: 770  DTDLSSAPKPVAAATIV--------SQQAEEGL--------TLPQDSAMTPPLPLQDTDL 813

Query: 1371 TTG-TPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTF 1429
            ++   P   +T  SQ  E+     Q S     L  +  ++S+ P P    T +       
Sbjct: 814  SSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVS------ 867

Query: 1430 YSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSF--GEKPIVIY 1487
                E+  +  Q     + LP +  +     GP    + TP      +    G +P+   
Sbjct: 868  -QQAEEGLTLPQDSAMTAPLPLQ--DTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATM 924

Query: 1488 KQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPS 1523
             Q        E    +   P P  +    PT+  P+
Sbjct: 925  AQ-------QEVGEALGPRPAPEEKNAALPTVPEPA 953


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 52.4 bits (124), Expect = 9e-06
 Identities = 176/851 (20%), Positives = 281/851 (33%), Gaps = 144/851 (16%)

Query: 971  PDSDLPRESLKMSAIPGLTDQKTV-PTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALK 1029
            PD+   + + K+S  P +T  K + P P++P  S + +E      ++   ++  T    K
Sbjct: 102  PDTSTTQHN-KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNK 160

Query: 1030 VSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGP-ADQMT 1088
             ++     D K +  + + +   ++     L P           + KV A P P A+  T
Sbjct: 161  QTS----TDGKEKTTSAKETQSIEKTSAKDLAP-----------TSKVLAKPTPKAETTT 205

Query: 1089 DTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQH 1148
              PA+ +        P        P S  PKE    ++       K   PT T ++ +  
Sbjct: 206  KGPALTTPKEPTPTTP------KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 259

Query: 1149 REKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLP 1208
            +E      ++  P T  P+E         P    T  P   +T    +  P      T P
Sbjct: 260  KEPAPTTTKEPAPTT--PKE---------PAPTTTKEPAPTTT----KSAP------TTP 298

Query: 1209 GSHIPEEAQKVSPVL----GPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEAL 1264
                P   +K +P       P   K  TPT        T++P     +      P + A 
Sbjct: 299  KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA- 357

Query: 1265 KISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQK 1324
              +   EP   T   PA T+T      ++PS    +  P+   T+ A   +  P P   K
Sbjct: 358  -PTTPKEPAPTTPKEPAPTTT------KEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTK 409

Query: 1325 TVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQ 1384
            +     P+T     ++P     +    + P E A        P       PT        
Sbjct: 410  SA----PTT----PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 461

Query: 1385 HTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVL 1444
             T+KP                A      P P   K   PT P      T +  +      
Sbjct: 462  TTKKP----------------APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505

Query: 1445 PHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVS 1504
            P    PEE L  +    P   T   P  T+P ++    P    K+  P    P+E     
Sbjct: 506  PAPTTPEE-LAPTTPEEPTPTTPEEPAPTTPKAAAPNTP----KEPAPT--TPKE----- 553

Query: 1505 VAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGP---ADQT 1561
                P   T   P  T+P  +      G+        + + E A      P P   A  T
Sbjct: 554  ----PAPTTPKEPAPTTPKETAPTTPKGT------APTTLKEPAPTTPKKPAPKELAPTT 603

Query: 1562 TGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSAL 1621
            T  PT T+      +KP        P G  P         + P E     P  P  ++  
Sbjct: 604  TKEPTSTTC-----DKP----APTTPKGTAP---------TTPKEPAPTTPKEPAPTTPK 645

Query: 1622 GEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLS 1681
            G  P T    A               AP      T   P  +TS     KP     +  +
Sbjct: 646  GTAPTTLKEPA--------PTTPKKPAPKELAPTTTKGPTSTTS----DKPAPTTPKETA 693

Query: 1682 DSHLPEEALKVPPVPGPDAQKTETPSVSS-SLYSYREKPIVFYQ---QALPD--SELTQE 1735
             +   E A   P  P P   +T  P+ S  S  +  ++P   ++   ++ P+  +E T +
Sbjct: 694  PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 753

Query: 1736 ALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQ 1795
            AL+ ++  +P    T     T    + T K   + +        T  A K++       +
Sbjct: 754  ALE-NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE 812

Query: 1796 KTGVSTVTSTS 1806
            KT  S +T+T+
Sbjct: 813  KTTESKITATT 823



 Score = 38.1 bits (87), Expect = 0.18
 Identities = 161/804 (20%), Positives = 255/804 (31%), Gaps = 127/804 (15%)

Query: 737  TEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAG 796
            T+E        P P   K   P    S+ +  ++P+   P+  A +   E          
Sbjct: 267  TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 326

Query: 797  PADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTS 856
            P   K   PT    A +                  P+E    +A   PA      PA T+
Sbjct: 327  PTTPKEPAPTTKEPAPT-----------------TPKEPAP-TAPKKPAPTTPKEPAPTT 368

Query: 857  TSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTG--IPSAPSSFYSHREK 914
                + +  ++PS    +  P    T+ A   +  P P   K+    P  PS   +    
Sbjct: 369  PKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 427

Query: 915  PIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSD 974
            P      T P    P    K +  +     K   PT        + K       + P   
Sbjct: 428  P------TTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477

Query: 975  LPRESLKMS--AIPGLTDQKTVPT------PTVPSG-SFSHREKPSIFYQQEWPDSYATE 1025
             P+E+   +   +   T +K  PT      PT P   + +  E+P+    +E   +    
Sbjct: 478  TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 537

Query: 1026 KALKVSTGPGPADQKTEIPAVQSSSYPQREKPSV-LYPQVLSDSHLPEESLKVSAFPGPA 1084
             A      P P   K   P       P   K +    P+  + + L E +      P P 
Sbjct: 538  AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 597

Query: 1085 DQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTS 1144
            +    T   P++    +  P      T P+   P    +    P     K   PT    +
Sbjct: 598  ELAPTTTKEPTSTTCDKPAP------TTPKGTAPTTPKE----PAPTTPKEPAPTTPKGT 647

Query: 1145 YSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQ 1204
                 ++P+       P T      ++++  T  G   T             +KP     
Sbjct: 648  APTTLKEPA-------PTTPKKPAPKELAPTTTKGPTST-----------TSDKPA---- 685

Query: 1205 QTLPGSHIPEEAQKVSPVL--GPADQKTGTPTPTSASYS---HTEKPGIFYQQVLPDN-- 1257
             T P    P   ++ +P     PA     TP PT++  S    T++P   ++   PD   
Sbjct: 686  PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS--PDEST 743

Query: 1258 -----HPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAK 1312
                  PT +AL+ S   EP   TT TPA T    +    K     +    +   T  A 
Sbjct: 744  PELSAEPTPKALENS-PKEPGVPTTKTPAATKPEMTT-TAKDKTTERDLRTTPETTTAAP 801

Query: 1313 NVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTT 1372
             ++       +KT    + +T    T+      Q   P    T   LK +  +  V  T 
Sbjct: 802  KMTKETATTTEKTTESKITAT---TTQVTSTTTQDTTPFKITT---LKTTTLAPKVTTTK 855

Query: 1373 GTPTVTS-TSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYS 1431
             T T T   +  + T KP              + A N  A      + T  P  P++   
Sbjct: 856  KTITTTEIMNKPEETAKPK-------------DRATNSKATTPKPQKPTKAPKKPTS--- 899

Query: 1432 HTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPI--VIYKQ 1489
             T+KP     + +P    P+        P P   T   P + +P+S   E  +       
Sbjct: 900  -TKKP-----KTMPRVRKPK------TTPTPRKMTSTMPEL-NPTSRIAEAMLQTTTRPN 946

Query: 1490 AFPEGHLPEESLKVSVAPGPVGQT 1513
              P   L E + K   A G  G+T
Sbjct: 947  QTPNSKLVEVNPKSEDAGGAEGET 970



 Score = 36.2 bits (82), Expect = 0.70
 Identities = 189/1028 (18%), Positives = 315/1028 (30%), Gaps = 133/1028 (12%)

Query: 1213 PEEAQKVSPVLGPADQKTGTPTPTSASYSH--------TEKPGIFYQQVLPDNHPTEEAL 1264
            P    +    L   D K  TP  ++  ++         T KP I  +  LP N  T +  
Sbjct: 82   PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP-INPRPSLPPNSDTSKET 140

Query: 1265 KISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQK 1324
             ++V  E   +T  T      + +  +EK +        S+  T+  +  SA       K
Sbjct: 141  SLTVNKETTVETKETTTTNKQTSTDGKEKTT--------SAKETQSIEKTSAKDLAPTSK 192

Query: 1325 TVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQ 1384
             +             KP        P +  T +   ++   EP   T   P  T+     
Sbjct: 193  VLA------------KP-------TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233

Query: 1385 HTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLP-STFYSHTEKPGSFYQQV 1443
             T   S       P    T+ A      P P   K   PT P     + T++P     + 
Sbjct: 234  PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 293

Query: 1444 LPHSHLPEEALEVSVAPGPVDQTIGTPTV-TSPSSSFGEKPIVIYKQAFPEGHLPEESLK 1502
             P +   E A      P P       PT    P+ +  ++P    K+  P    P+E   
Sbjct: 294  APTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT--TPKE--- 347

Query: 1503 VSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTT 1562
                P P      APT T    +    K  +           P+E    ++   P     
Sbjct: 348  ----PAPTAPKKPAPT-TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 402

Query: 1563 GIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALG 1622
              PT T ++ +  ++P     +  P    P+E    +    P +     P  P  ++   
Sbjct: 403  PAPTTTKSAPTTPKEPSPTTTKE-PAPTTPKEPAPTT----PKKPAPTTPKEPAPTTPKE 457

Query: 1623 EKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSD 1682
              P T  + A               AP    + T T P    + +   KP     + L+ 
Sbjct: 458  PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAP 516

Query: 1683 SHLPEEALKVPPVPGPDAQKT---ETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKV 1739
            +   E     P  P P   K     TP   +        P    + A    + T      
Sbjct: 517  TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 576

Query: 1740 SAVP------------QPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVS 1787
               P            +PA ++   +T      +  +KP  +  +    +   E A    
Sbjct: 577  GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 636

Query: 1788 NVPGPADQK-TGVSTVTSTSYSHREKPIVSYQRELPHFTEAG--LKILRVPGPADQKTGI 1844
              P P   K T  +T+   + +  +KP     +EL   T  G        P P   K   
Sbjct: 637  KEPAPTTPKGTAPTTLKEPAPTTPKKPA---PKELAPTTTKGPTSTTSDKPAPTTPKETA 693

Query: 1845 NILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKAS 1904
               P    P           E P     T   +  P    + T I               
Sbjct: 694  PTTPKEPAPTTPKKPAPTTPETP---PPTTSEVSTPTTTKEPTTI--------------- 735

Query: 1905 IFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEE 1964
                 + PD +   L+    P   +   + P VP +      KP + +  +      TE 
Sbjct: 736  ----HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK---DKTTER 788

Query: 1965 ALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPD---DQKTEFPAATLSSYS 2021
             L+ +P +  A  K  +    +++   + + K+  +T  +        T F   TL + +
Sbjct: 789  DLRTTPETTTAAPK--MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 846

Query: 2022 QIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPEL 2081
                PK++T      +KT + T   +   +T KP            + +   K    P  
Sbjct: 847  L--APKVTTT-----KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 899

Query: 2082 TDVNTGKP-VSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIP-------------- 2126
            T      P V    +     K     P+  P S + E +L+ +T P              
Sbjct: 900  TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPK 959

Query: 2127 ----GPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDRH-LTEDALKISSALGQADQITG 2181
                G A  +T      P  F     PD+ Y   +P++  +    L   + +     + G
Sbjct: 960  SEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDG 1019

Query: 2182 LQTVPSGT 2189
            L T+ +GT
Sbjct: 1020 LTTLRNGT 1027


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 52.4 bits (124), Expect = 9e-06
 Identities = 176/851 (20%), Positives = 281/851 (33%), Gaps = 144/851 (16%)

Query: 971  PDSDLPRESLKMSAIPGLTDQKTV-PTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALK 1029
            PD+   + + K+S  P +T  K + P P++P  S + +E      ++   ++  T    K
Sbjct: 143  PDTSTTQHN-KVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNK 201

Query: 1030 VSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGP-ADQMT 1088
             ++     D K +  + + +   ++     L P           + KV A P P A+  T
Sbjct: 202  QTS----TDGKEKTTSAKETQSIEKTSAKDLAP-----------TSKVLAKPTPKAETTT 246

Query: 1089 DTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQH 1148
              PA+ +        P        P S  PKE    ++       K   PT T ++ +  
Sbjct: 247  KGPALTTPKEPTPTTP------KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 300

Query: 1149 REKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLP 1208
            +E      ++  P T  P+E         P    T  P   +T    +  P      T P
Sbjct: 301  KEPAPTTTKEPAPTT--PKE---------PAPTTTKEPAPTTT----KSAP------TTP 339

Query: 1209 GSHIPEEAQKVSPVL----GPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEAL 1264
                P   +K +P       P   K  TPT        T++P     +      P + A 
Sbjct: 340  KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA- 398

Query: 1265 KISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQK 1324
              +   EP   T   PA T+T      ++PS    +  P+   T+ A   +  P P   K
Sbjct: 399  -PTTPKEPAPTTPKEPAPTTT------KEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTK 450

Query: 1325 TVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQ 1384
            +     P+T     ++P     +    + P E A        P       PT        
Sbjct: 451  SA----PTT----PKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 502

Query: 1385 HTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVL 1444
             T+KP                A      P P   K   PT P      T +  +      
Sbjct: 503  TTKKP----------------APTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546

Query: 1445 PHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVS 1504
            P    PEE L  +    P   T   P  T+P ++    P    K+  P    P+E     
Sbjct: 547  PAPTTPEE-LAPTTPEEPTPTTPEEPAPTTPKAAAPNTP----KEPAPT--TPKE----- 594

Query: 1505 VAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGP---ADQT 1561
                P   T   P  T+P  +      G+        + + E A      P P   A  T
Sbjct: 595  ----PAPTTPKEPAPTTPKETAPTTPKGT------APTTLKEPAPTTPKKPAPKELAPTT 644

Query: 1562 TGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSAL 1621
            T  PT T+      +KP        P G  P         + P E     P  P  ++  
Sbjct: 645  TKEPTSTTC-----DKP----APTTPKGTAP---------TTPKEPAPTTPKEPAPTTPK 686

Query: 1622 GEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLS 1681
            G  P T    A               AP      T   P  +TS     KP     +  +
Sbjct: 687  GTAPTTLKEPA--------PTTPKKPAPKELAPTTTKGPTSTTS----DKPAPTTPKETA 734

Query: 1682 DSHLPEEALKVPPVPGPDAQKTETPSVSS-SLYSYREKPIVFYQ---QALPD--SELTQE 1735
             +   E A   P  P P   +T  P+ S  S  +  ++P   ++   ++ P+  +E T +
Sbjct: 735  PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPK 794

Query: 1736 ALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQ 1795
            AL+ ++  +P    T     T    + T K   + +        T  A K++       +
Sbjct: 795  ALE-NSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTE 853

Query: 1796 KTGVSTVTSTS 1806
            KT  S +T+T+
Sbjct: 854  KTTESKITATT 864



 Score = 38.1 bits (87), Expect = 0.18
 Identities = 161/804 (20%), Positives = 255/804 (31%), Gaps = 127/804 (15%)

Query: 737  TEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAG 796
            T+E        P P   K   P    S+ +  ++P+   P+  A +   E          
Sbjct: 308  TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 367

Query: 797  PADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTS 856
            P   K   PT    A +                  P+E    +A   PA      PA T+
Sbjct: 368  PTTPKEPAPTTKEPAPT-----------------TPKEPAP-TAPKKPAPTTPKEPAPTT 409

Query: 857  TSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTG--IPSAPSSFYSHREK 914
                + +  ++PS    +  P    T+ A   +  P P   K+    P  PS   +    
Sbjct: 410  PKEPAPTTTKEPSPTTPKE-PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 468

Query: 915  PIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSD 974
            P      T P    P    K +  +     K   PT        + K       + P   
Sbjct: 469  P------TTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518

Query: 975  LPRESLKMS--AIPGLTDQKTVPT------PTVPSG-SFSHREKPSIFYQQEWPDSYATE 1025
             P+E+   +   +   T +K  PT      PT P   + +  E+P+    +E   +    
Sbjct: 519  TPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA 578

Query: 1026 KALKVSTGPGPADQKTEIPAVQSSSYPQREKPSV-LYPQVLSDSHLPEESLKVSAFPGPA 1084
             A      P P   K   P       P   K +    P+  + + L E +      P P 
Sbjct: 579  AAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 638

Query: 1085 DQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTS 1144
            +    T   P++    +  P      T P+   P    +    P     K   PT    +
Sbjct: 639  ELAPTTTKEPTSTTCDKPAP------TTPKGTAPTTPKE----PAPTTPKEPAPTTPKGT 688

Query: 1145 YSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQ 1204
                 ++P+       P T      ++++  T  G   T             +KP     
Sbjct: 689  APTTLKEPA-------PTTPKKPAPKELAPTTTKGPTST-----------TSDKPA---- 726

Query: 1205 QTLPGSHIPEEAQKVSPVL--GPADQKTGTPTPTSASYS---HTEKPGIFYQQVLPDN-- 1257
             T P    P   ++ +P     PA     TP PT++  S    T++P   ++   PD   
Sbjct: 727  PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKS--PDEST 784

Query: 1258 -----HPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAK 1312
                  PT +AL+ S   EP   TT TPA T    +    K     +    +   T  A 
Sbjct: 785  PELSAEPTPKALENS-PKEPGVPTTKTPAATKPEMTT-TAKDKTTERDLRTTPETTTAAP 842

Query: 1313 NVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTT 1372
             ++       +KT    + +T    T+      Q   P    T   LK +  +  V  T 
Sbjct: 843  KMTKETATTTEKTTESKITAT---TTQVTSTTTQDTTPFKITT---LKTTTLAPKVTTTK 896

Query: 1373 GTPTVTS-TSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYS 1431
             T T T   +  + T KP              + A N  A      + T  P  P++   
Sbjct: 897  KTITTTEIMNKPEETAKPK-------------DRATNSKATTPKPQKPTKAPKKPTS--- 940

Query: 1432 HTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPI--VIYKQ 1489
             T+KP     + +P    P+        P P   T   P + +P+S   E  +       
Sbjct: 941  -TKKP-----KTMPRVRKPK------TTPTPRKMTSTMPEL-NPTSRIAEAMLQTTTRPN 987

Query: 1490 AFPEGHLPEESLKVSVAPGPVGQT 1513
              P   L E + K   A G  G+T
Sbjct: 988  QTPNSKLVEVNPKSEDAGGAEGET 1011



 Score = 36.2 bits (82), Expect = 0.70
 Identities = 189/1028 (18%), Positives = 315/1028 (30%), Gaps = 133/1028 (12%)

Query: 1213 PEEAQKVSPVLGPADQKTGTPTPTSASYSH--------TEKPGIFYQQVLPDNHPTEEAL 1264
            P    +    L   D K  TP  ++  ++         T KP I  +  LP N  T +  
Sbjct: 123  PPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKP-INPRPSLPPNSDTSKET 181

Query: 1265 KISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQK 1324
             ++V  E   +T  T      + +  +EK +        S+  T+  +  SA       K
Sbjct: 182  SLTVNKETTVETKETTTTNKQTSTDGKEKTT--------SAKETQSIEKTSAKDLAPTSK 233

Query: 1325 TVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQ 1384
             +             KP        P +  T +   ++   EP   T   P  T+     
Sbjct: 234  VLA------------KP-------TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274

Query: 1385 HTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLP-STFYSHTEKPGSFYQQV 1443
             T   S       P    T+ A      P P   K   PT P     + T++P     + 
Sbjct: 275  PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 334

Query: 1444 LPHSHLPEEALEVSVAPGPVDQTIGTPTV-TSPSSSFGEKPIVIYKQAFPEGHLPEESLK 1502
             P +   E A      P P       PT    P+ +  ++P    K+  P    P+E   
Sbjct: 335  APTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT--TPKE--- 388

Query: 1503 VSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTT 1562
                P P      APT T    +    K  +           P+E    ++   P     
Sbjct: 389  ----PAPTAPKKPAPT-TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 443

Query: 1563 GIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALG 1622
              PT T ++ +  ++P     +  P    P+E    +    P +     P  P  ++   
Sbjct: 444  PAPTTTKSAPTTPKEPSPTTTKE-PAPTTPKEPAPTT----PKKPAPTTPKEPAPTTPKE 498

Query: 1623 EKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQTLSD 1682
              P T  + A               AP    + T T P    + +   KP     + L+ 
Sbjct: 499  PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTP-EKLAPTTPEKPAPTTPEELAP 557

Query: 1683 SHLPEEALKVPPVPGPDAQKT---ETPSVSSSLYSYREKPIVFYQQALPDSELTQEALKV 1739
            +   E     P  P P   K     TP   +        P    + A    + T      
Sbjct: 558  TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 617

Query: 1740 SAVP------------QPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVS 1787
               P            +PA ++   +T      +  +KP  +  +    +   E A    
Sbjct: 618  GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTP 677

Query: 1788 NVPGPADQK-TGVSTVTSTSYSHREKPIVSYQRELPHFTEAG--LKILRVPGPADQKTGI 1844
              P P   K T  +T+   + +  +KP     +EL   T  G        P P   K   
Sbjct: 678  KEPAPTTPKGTAPTTLKEPAPTTPKKPA---PKELAPTTTKGPTSTTSDKPAPTTPKETA 734

Query: 1845 NILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSSSYSNREKAS 1904
               P    P           E P     T   +  P    + T I               
Sbjct: 735  PTTPKEPAPTTPKKPAPTTPETP---PPTTSEVSTPTTTKEPTTI--------------- 776

Query: 1905 IFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVPLSYYSRREKPSVISQQELPDSHLTEE 1964
                 + PD +   L+    P   +   + P VP +      KP + +  +      TE 
Sbjct: 777  ----HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK---DKTTER 829

Query: 1965 ALKVSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPD---DQKTEFPAATLSSYS 2021
             L+ +P +  A  K  +    +++   + + K+  +T  +        T F   TL + +
Sbjct: 830  DLRTTPETTTAAPK--MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTT 887

Query: 2022 QIEKPKISTVIGPNDQKTPSQTAFHSSYSQTVKPNILFQQQLPDRDQSKGILKISAVPEL 2081
                PK++T      +KT + T   +   +T KP            + +   K    P  
Sbjct: 888  L--APKVTTT-----KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTS 940

Query: 2082 TDVNTGKP-VSLSSSYFHREKSNIFSPQELPGSHVTEDVLKVSTIP-------------- 2126
            T      P V    +     K     P+  P S + E +L+ +T P              
Sbjct: 941  TKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPK 1000

Query: 2127 ----GPAGQKTVLPTALPSSFSHREKPDIFYQKDLPDRH-LTEDALKISSALGQADQITG 2181
                G A  +T      P  F     PD+ Y   +P++  +    L   + +     + G
Sbjct: 1001 SEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDG 1060

Query: 2182 LQTVPSGT 2189
            L T+ +GT
Sbjct: 1061 LTTLRNGT 1068


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 163/779 (20%), Positives = 248/779 (31%), Gaps = 136/779 (17%)

Query: 1090 TPAVPSTFYSQREKPGIFYQQTLP-----------ESHLPKEALKISVAPGLADQKTGTP 1138
            TPA  ST  +    PG  +  T P            +  P   L+ +  P +      TP
Sbjct: 2581 TPATSSTA-TPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTP 2639

Query: 1139 TVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREK 1198
            TVTS+  +      +     AL  T     A  V+ +       TW      T  SQ   
Sbjct: 2640 TVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTW------TRLSQTTT 2693

Query: 1199 PGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNH 1258
            P        P S  PE A   S VL      T T T T A+ S             P + 
Sbjct: 2694 PTATMSTATPSS-TPETAH-TSTVL------TATATTTGATGS----------VATPSST 2735

Query: 1259 P-TEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAV 1317
            P T    K+     P   TTG  A  S+S       P      + P++         S++
Sbjct: 2736 PGTAHTTKV-----PTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTR--GSTVTPSSI 2788

Query: 1318 PGPADQKTVIPILPSTF--------YSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVD 1369
            PG     TV+    +T          S T+  G  +   +P++  T     +  +S    
Sbjct: 2789 PGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTV 2848

Query: 1370 QTTGTPTVTSTSYSQHTEKPSIFYQQSLPG-SHLTEEAKNVSAVPGPGDRKTGIPTLP-S 1427
            +T  T   +    + H  +PS     +L   +  T+ +    + P P  R T  P  P +
Sbjct: 2849 RTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGT 2908

Query: 1428 TFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIY 1487
            T   HT           P        L  S    P+   +          + G +P   +
Sbjct: 2909 TTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVV----------TMGCEPQCAW 2958

Query: 1488 KQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEE 1547
             +     +           PGP G           +YS  RA  G+  +   LG +    
Sbjct: 2959 SEWLDYSY---------PMPGPSGG-------DFDTYSNIRAAGGAVCEQP-LGLE---- 2997

Query: 1548 ALRVSSAPGPADQTTGIPTITSTSYSFG-----EKPIVNYKQAF---------PDGHLPE 1593
              R  + PG   +  G   +   S  FG      + +  +K  F           GH P 
Sbjct: 2998 -CRAQAQPGVPLRELG--QVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCP- 3053

Query: 1594 EALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPG--- 1650
                    S P    T +P+   G++ +    +T        +         S+ PG   
Sbjct: 3054 --------STPATSSTAMPSSTPGTTWI----LTELTTTATTTESTGSTATPSSTPGTTW 3101

Query: 1651 ----PADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPGPDAQKTETP 1706
                P+   T T+P  ST+ ++        Q T    H+   A   P V    A    +P
Sbjct: 3102 ILTEPSTTATVTVPTGSTATASS------TQATAGTPHVSTTA-TTPTVTSSKATPFSSP 3154

Query: 1707 SVSSSLYSYRE---KPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHT 1763
              +++L + R     P      A+P S L     ++S    P      +ST T S    T
Sbjct: 3155 GTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPT---ATMSTATPSSTPET 3211

Query: 1764 EKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELP 1822
               +         +  T      S+ PG A   T V T T+T ++          R LP
Sbjct: 3212 VHTSTVLTTTATTTGATGSVATPSSTPGTA-HTTKVLTTTTTGFTATPSSSPGTARTLP 3269



 Score = 47.0 bits (110), Expect = 4e-04
 Identities = 235/1158 (20%), Positives = 392/1158 (33%), Gaps = 175/1158 (15%)

Query: 591  PDSHLTEEALKVSAAPG----LADQTTGMSTLTSTSYSH--REKPGTFYQQELPESNLTE 644
            P +  T      S+ PG    L +QTT  +T  +T  +      PGT    ++  S  T 
Sbjct: 3555 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3614

Query: 645  EPLEVSAAPGPVEQKTG--IPTVSST-------SHSHVEDLLFFYRQTLPDGHLTDQALK 695
                 S A      +T   +P ++ST       S + +         TLP+   T  A  
Sbjct: 3615 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3674

Query: 696  VSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKT 755
             +       + T T+TVL+T                A + +   +++  S+TPG     T
Sbjct: 3675 STIHPSSTPETTHTSTVLTTK---------------ATTTRATSSMSTPSSTPGTTWILT 3719

Query: 756  EIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHR 815
            E+    +++ +    P+         + +  E    + V  P    TG     SS  +  
Sbjct: 3720 ELTTAATTTAATG--PTATPSSTPGTTWILTEPSTTATVTVP----TGSTATASSTRATA 3773

Query: 816  EKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQT 875
              L V    A   + +   A   S+  G A   T  PA+ ST++        P+A     
Sbjct: 3774 GTLKVLTSTATTPTVISSRATPSSS-PGTA---TALPALRSTATT-------PTATSVTA 3822

Query: 876  LPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKV 935
            +P+S L     ++S    P    T   + PSS         + +  T         A   
Sbjct: 3823 IPSSSLGTAWTRLSQTTTP--TATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPS 3880

Query: 936  SAVSVLAAQKTGTPTVS--SNSHSHSEKSSVFYQQELPDSDLPR---ESLKMSAIPGLTD 990
            S        K  T T +  + + S S  +++     +  +  P     ++  S+IPG T 
Sbjct: 3881 STPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTH 3940

Query: 991  QKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKT----EIPAV 1046
              TV T T  + +      P          S +T+ +    T P P    T     +P  
Sbjct: 3941 TATVLTTTTTTVATGSMATP----------SSSTQTSGTTHTPPVPNTTATTHGRSLPP- 3989

Query: 1047 QSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGI 1106
             SS +  R   +     +L  +H+ E          P+   + TPA  +T  +Q   P  
Sbjct: 3990 -SSPHTVRTAWTSATSGILGTTHITE----------PSTVTSHTPAA-TTSTTQHSTPA- 4036

Query: 1107 FYQQTLPESHLPKEALKISVAPGLAD--QKTGTPTVTSTSYSQHREKPSIFHQQALPGTH 1164
                 L   H      +   +PG        GT   T+T+        ++     LP + 
Sbjct: 4037 -----LSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTL-----LPSS- 4085

Query: 1165 IPEEAQKVSAVT-GPGNQKTWIPRV-------------LSTFYSQREKPGIFYQQTLPGS 1210
             P  A   + VT G   Q  W   +               T+ + R   G   +Q L G 
Sbjct: 4086 -PTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPL-GL 4143

Query: 1211 HIPEEAQKVSPVLGPADQKTGTPTPTSASYS----HTEKPGIFYQQVLPDNHPTEEALKI 1266
                +AQ   P+     ++ G     S  +     + E+ G F               +I
Sbjct: 4144 ECRAQAQPGVPL-----RELGQVVECSLDFGLVCRNREQVGKFKMCF---------NYEI 4189

Query: 1267 SVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTV 1326
             V          TPA +ST+ +      + +    L ++  T E+   +A P      T 
Sbjct: 4190 RVFCCNYGHCPSTPATSSTA-TPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTW 4248

Query: 1327 IPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHT 1386
            I   PST  + T   G         S  T  + + +  +  V  T  TPTVTS+  +  +
Sbjct: 4249 ILTEPSTTATVTVPTG---------STATASSTQATAGTPHVSTTATTPTVTSSKATPFS 4299

Query: 1387 EKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPH 1446
               +     +L  +  T  A + +A+P      T       T  S T  P +      P 
Sbjct: 4300 SPGTATALPALRSTATTPTATSFTAIPSSSLGTTW------TRLSQTTTPTATMSTATP- 4352

Query: 1447 SHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVA 1506
            S  PE A   +V       T  T +V +PSS+    P   +    P       ++  S +
Sbjct: 4353 SSTPETAHTSTVLTTTATTTRATGSVATPSST----PGTAHTTKVPTTTTTGFTVTPSSS 4408

Query: 1507 PG-----PVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQT 1561
            PG     PV  +T     TS S     +  G+ +   +L +     A    + P  + QT
Sbjct: 4409 PGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQT 4468

Query: 1562 TG------IPTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGP 1615
            +G      +P  T+T++     P   +             L  + ++ P+   +  PA  
Sbjct: 4469 SGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT 4528

Query: 1616 LGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIF 1675
             G+        T +    L SP +       + P P      T P H+T+ ++R      
Sbjct: 4529 TGT--------TQHSTPALSSP-HPSSRTTESPPSPG----TTTPGHTTA-TSRTTATAT 4574

Query: 1676 YQQTLSDSHLPEEALKVP 1693
              +T + + LP      P
Sbjct: 4575 PSKTRTSTLLPSSPTSAP 4592



 Score = 44.3 bits (103), Expect = 0.003
 Identities = 188/921 (20%), Positives = 313/921 (33%), Gaps = 135/921 (14%)

Query: 948  TPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPG--------LTDQKTVPTPTV 999
            TP  SS +   S   + +   EL  +    ES   +A P         LT+  T  T TV
Sbjct: 3055 TPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTV 3114

Query: 1000 PSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSV 1059
            P+G                  S AT  + + + G          P V SS       P  
Sbjct: 3115 PTG------------------STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPG- 3155

Query: 1060 LYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPK 1119
                  + + LP  +L+ +A    A   T   A+PS+  S         Q T P      
Sbjct: 3156 ------TATALP--ALRSTATTPTATSFT---AIPSS--SLGTTWTRLSQTTTP------ 3196

Query: 1120 EALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAV---- 1175
             A   +  P    +   T TV +T+ +      S+    + PGT    +    +      
Sbjct: 3197 TATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTA 3256

Query: 1176 ---TGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPG-SHIPEEAQKVSPVLGPADQKTG 1231
               + PG  +T +P  +ST  +   +       ++PG +H P      +  +      TG
Sbjct: 3257 TPSSSPGTART-LPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVA-----TG 3310

Query: 1232 TPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYR 1291
            +    S+S   T+  G  +   +P+   T     +S +S    +T  T A + T  + + 
Sbjct: 3311 SMATPSSS---TQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 3367

Query: 1292 EKPSIFYQQS-LPSSHLTEEAKNVSAVPGPADQKTVIPILP-STFYSHTEKPGVFYQQVL 1349
             +PS     +   ++  T+ +    + P P+ + T  P  P +T   HT           
Sbjct: 3368 TEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATAT 3427

Query: 1350 PHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPG---------S 1400
            P    T   L  S  S P+     T  VT     Q      + Y   +PG         S
Sbjct: 3428 PSKTRTSTLLPSSPTSAPI-----TTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYS 3482

Query: 1401 HLTEEAKNV-----------SAVPGPGDRKTGIPTLPSTFYS----HTEKPGSFYQQVLP 1445
            ++      V            A PG   R+ G     S  +     + E+ G F  ++  
Sbjct: 3483 NIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKF--KMCF 3540

Query: 1446 HSHLPEEALEVSVAPG-PVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVS 1504
            +  +          P  P   +  TP+ T  ++    +           G     S    
Sbjct: 3541 NYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPG 3600

Query: 1505 VAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGI 1564
             AP P   T+   T T+P+ +  +A S S  + A   + +P   L  ++    A   T I
Sbjct: 3601 TAPPPKVLTS---TATTPTATSSKATSSSSPRTA---TTLP--VLTSTATKSTATSFTPI 3652

Query: 1565 PTIT-STSYSFGEK---PIVNYKQAFPDGHLPEEALKVSIVS--GPTEKKTDIPAGPLGS 1618
            P+ T  T+ +  E+   P+       P    PE     ++++    T + T   + P  S
Sbjct: 3653 PSFTLGTTGTLPEQTTTPMATMSTIHPSS-TPETTHTSTVLTTKATTTRATSSMSTP--S 3709

Query: 1619 SALGEKPI-TFYRQALLDSPLNKEVVKVSAAPG-------PADQKTETLPVHSTSYSNRG 1670
            S  G   I T    A   +         S+ PG       P+   T T+P  ST+ ++  
Sbjct: 3710 STPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASST 3769

Query: 1671 KPVIFYQQTLSDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSYRE---KPIVFYQQAL 1727
            +      + L+ +         P V    A  + +P  +++L + R     P      A+
Sbjct: 3770 RATAGTLKVLTST------ATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAI 3823

Query: 1728 PDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVS 1787
            P S L     ++S    P      +ST T S    T   +         +  T      S
Sbjct: 3824 PSSSLGTAWTRLSQTTTPT---ATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPS 3880

Query: 1788 NVPGPADQKTGVSTVTSTSYS 1808
            + PG A   T V T T+T ++
Sbjct: 3881 STPGTA-HTTKVPTTTTTGFT 3900



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 102/470 (21%), Positives = 162/470 (34%), Gaps = 70/470 (14%)

Query: 948  TPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPG--------LTDQKTVPTPTV 999
            TP  SS +   S   + +   +L  +    ES   +A P         LT+  T  T TV
Sbjct: 4202 TPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTV 4261

Query: 1000 PSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSV 1059
            P+G                  S AT  + + + G          P V SS       P  
Sbjct: 4262 PTG------------------STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPG- 4302

Query: 1060 LYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPK 1119
                  + + LP  +L+ +A    A   T   A+PS+  S         Q T P      
Sbjct: 4303 ------TATALP--ALRSTATTPTATSFT---AIPSS--SLGTTWTRLSQTTTP------ 4343

Query: 1120 EALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPG----THIPEEAQKVSAV 1175
             A   +  P    +   T TV +T+ +  R   S+    + PG    T +P        V
Sbjct: 4344 TATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTV 4403

Query: 1176 T---GPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPG-SHIPEEAQKVSPVLGPADQKTG 1231
            T    PG  +T  P  +ST  +           ++PG +H P      +  +      TG
Sbjct: 4404 TPSSSPGTART-PPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVA-----TG 4457

Query: 1232 TPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYR 1291
            +    S+S   T+  G  +   +P+   T     +S +S    +T  T A + T  + + 
Sbjct: 4458 SMATPSSS---TQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI 4514

Query: 1292 EKPSIFYQQS-LPSSHLTEEAKNVSAVPGPADQKTVIPILP-STFYSHTEKPGVFYQQVL 1349
             +PS     +   ++  T+ +    + P P+ + T  P  P +T   HT           
Sbjct: 4515 TEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATAT 4574

Query: 1350 PHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPG 1399
            P    T   L  S  S P+     T  VT+    Q      + Y   +PG
Sbjct: 4575 PSKTRTSTLLPSSPTSAPI-----TTVVTTGCEPQCAWSEWLDYSYPMPG 4619



 Score = 38.9 bits (89), Expect = 0.11
 Identities = 78/357 (21%), Positives = 124/357 (34%), Gaps = 37/357 (10%)

Query: 1137 TPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQR 1196
            T T T+T+ +     PS     + PGT  P +      +T P    T      ++  S R
Sbjct: 4727 TTTATTTASTGSTATPS-----STPGTAPPPKV-----LTSPATTPTATSSKATSSSSPR 4776

Query: 1197 EKPGIFYQQTLPGSHIPEEAQKVSPV-------LGPADQKTGTPTPTSASYSHTEKPGIF 1249
                +     L  +     A  V+P+        G   ++T TP  T ++   +  P   
Sbjct: 4777 TATTL---PVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETT 4833

Query: 1250 YQQ-VLPDNHPTEEALKISVASEPVDQTTG-----TPAVTSTSYSQYREKPSIFYQQSLP 1303
            +   VL     T  A   +        TT      T A T+T+ +     PS     +  
Sbjct: 4834 HTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWI 4893

Query: 1304 SSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISV 1363
             + LT  A   ++    A   +     P T +  TE        V   S  T  + + + 
Sbjct: 4894 LTELTTTATTTASTGSTATPSST----PGTTWILTEPSTTATVTVPTGSTATASSTQATA 4949

Query: 1364 ASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIP 1423
             +  V  T  TPTVTS+  +  +   +     +L  +  T  A + +A+P      T   
Sbjct: 4950 GTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTW-- 5007

Query: 1424 TLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFG 1480
                T  S T  P +      P S  PE     +V       T  T +V +PSS+ G
Sbjct: 5008 ----TRLSQTTTPTATMSTATP-SSTPETVHTSTVLTATATTTGATGSVATPSSTPG 5059



 Score = 38.1 bits (87), Expect = 0.18
 Identities = 80/340 (23%), Positives = 118/340 (34%), Gaps = 59/340 (17%)

Query: 529  TTTGQHTDTLNQKTLADTHLTEETLKV---TAIPEPADQKTATP-------TVLSSSHSH 578
            TT      T +  T + T  T  TLKV   TA         ATP       T L +  S 
Sbjct: 3752 TTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRST 3811

Query: 579  RGKPSIFYQQGLPDSHL-----------TEEALKVSAAPGLADQTTGMST-LTSTSYSHR 626
               P+      +P S L           T  A   +A P    +T   ST LT+T+ + R
Sbjct: 3812 ATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTR 3871

Query: 627  ---------EKPGTFYQQELPESNLTEEPLEVSAAPG--------------PVEQKTGIP 663
                       PGT +  ++P +  T      S++PG              P  + + + 
Sbjct: 3872 ATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVT 3931

Query: 664  TVSSTSHSHVEDLLFFYRQTLPDGHLT--DQALKVSAVSGPADQKTGTATV------LST 715
              S    +H   +L     T+  G +     + + S  +        TAT        S+
Sbjct: 3932 PSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSS 3991

Query: 716  PHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTE--IPAVQSSSYSQREKPSI 773
            PH+ R             +H TE + T  S TP      T+   PA+ S   S R   S 
Sbjct: 3992 PHTVRTAWTSATSGILGTTHITEPS-TVTSHTPAATTSTTQHSTPALSSPHPSSRTTESP 4050

Query: 774  LYPQDLADSHLPEEGLKVSAVAGPADQKTG--LPTVPSSA 811
              P      H      + +A A P+  +T   LP+ P+SA
Sbjct: 4051 PSPGTTTPGHTRGTS-RTTATATPSKTRTSTLLPSSPTSA 4089



 Score = 37.7 bits (86), Expect = 0.24
 Identities = 79/379 (20%), Positives = 116/379 (30%), Gaps = 26/379 (6%)

Query: 543  LADTHLTEETLKVTAIPEPADQKT-------ATPTVLSSSHSHRGKPSIFYQQGLPDSHL 595
            L  T  T E+   TA P      T        T TV   + S     S     G P    
Sbjct: 4224 LTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVST 4283

Query: 596  TEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGP 655
            T     V+++      + G +T      S    P       +P S+L      +S    P
Sbjct: 4284 TATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 4343

Query: 656  VEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQ-KTGTATVLS 714
                +     S+   +H   +L     T      T      S+  G A   K  T T   
Sbjct: 4344 TATMSTATPSSTPETAHTSTVL---TTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTG 4400

Query: 715  TPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSIL 774
               +    PG         S  T  T +  + TP      T  P V +++ +     S+ 
Sbjct: 4401 FTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMA 4460

Query: 775  YP----QDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSH 830
             P    Q    +H P        V        G    PSS ++ R          L  +H
Sbjct: 4461 TPSSSTQTSGTTHTPP-------VPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTH 4513

Query: 831  LPEEALKVSAVSGPADGKT--GTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKV 888
            + E +   S       G T   TPA++S   +S +    PS     T P           
Sbjct: 4514 ITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP--GTTTPGHTTATSRTTA 4571

Query: 889  SIVPGPGDQKTGIPSAPSS 907
            +  P      T +PS+P+S
Sbjct: 4572 TATPSKTRTSTLLPSSPTS 4590



 Score = 37.4 bits (85), Expect = 0.31
 Identities = 52/189 (27%), Positives = 71/189 (37%), Gaps = 27/189 (14%)

Query: 1398 PGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVS 1457
            P +  T      S+ PG     T I T P+T  + T   GS        +  P   L  +
Sbjct: 2579 PSTPATSSTATPSSTPGT----TWILTKPTTTATTTASTGS--------TATPTSTLRTA 2626

Query: 1458 VAPGPVDQTIGTPTVTS----PSSSFGEK---PIVIYKQAFPEGH--LPEESLKVSVAPG 1508
              P  +  T  TPTVTS    PSSS G     P +      P      P  S  +     
Sbjct: 2627 PPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWT 2686

Query: 1509 PVGQTTGAPTIT----SPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGI 1564
             + QTT  PT T    +PS +   A + +        +         SS PG A  TT +
Sbjct: 2687 RLSQTT-TPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTA-HTTKV 2744

Query: 1565 PTITSTSYS 1573
            PT T+T ++
Sbjct: 2745 PTTTTTGFT 2753


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 233/1128 (20%), Positives = 356/1128 (31%), Gaps = 180/1128 (15%)

Query: 543  LADTHLTEETLKVTAIPEPADQKT-------ATPTVLSSSHSHRGKPSIFYQQGLPDSHL 595
            L  T  T E+   TA P      T        T TV   + S     S     G P    
Sbjct: 3699 LTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVST 3758

Query: 596  TEEALKVSAAPGLADQTTGMSTLTSTSYSHREKPGTFYQQELPESNLTEEPLEVSAAPGP 655
            T     V+++      + G +T      S    P       +P S+L      +S    P
Sbjct: 3759 TATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP 3818

Query: 656  VEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQ-KTGTATVLS 714
                +     S+   +H   +L     T      T      S+  G A   K  T T   
Sbjct: 3819 TATMSTATPSSTPETAHTSTVL---TTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTG 3875

Query: 715  TPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPSIL 774
               +    PG         S  T  T +  + TP      T  P V +++ +     S+ 
Sbjct: 3876 FTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMA 3935

Query: 775  YPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEE 834
             P     +      L  +A    A   TG  T PSS               L  +     
Sbjct: 3936 TPSSSTQTSGTPPSLITTATTITA---TGSTTNPSSTPGTTP-----IPPVLTTTATTPA 3987

Query: 835  ALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFY----------QQTLPNSHLTEE 884
            A   +     A G T TP V +T++ +      PS+ +            TL  +H+TE 
Sbjct: 3988 ATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEP 4047

Query: 885  ALKVSIVP----GPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLFPEEALKVSAVSV 940
            +   S  P    G     T   S+P       E P        P    P      S  + 
Sbjct: 4048 STGTSHTPAATTGTTQHSTPALSSPHPSSRTTESP------PSPGTTTPGHTTATSRTTA 4101

Query: 941  LAA-QKTGTPTVSSNSHSHSEKSSVF---------------YQQELP---DSDLPRESLK 981
             A   KT T T+  +S + +  ++V                Y   +P     D    S  
Sbjct: 4102 TATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNI 4161

Query: 982  MSAIPGLTDQ------KTVPTPTVPSGSFS--------------HREKPSIFYQ------ 1015
             +A   + +Q      +    P VP G                 +RE+   F        
Sbjct: 4162 RAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEI 4221

Query: 1016 -------QEWPDSYATEKALKVSTGPGPADQKTEI-------PAVQSSSYPQREKPSVLY 1061
                      P + AT      S+ PG     TE+        +  S++ P     +   
Sbjct: 4222 RVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPP 4281

Query: 1062 PQVL-SDSHLP-EESLKVSAFPGPADQMT----DTPAVPSTFYSQREKPGIFYQQT--LP 1113
            P+VL S +  P   S K ++   P    T     + A  ST  S    P      T  LP
Sbjct: 4282 PKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLP 4341

Query: 1114 ESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVS 1173
            E      A   ++ P    + T T TV +T  +  R   S     + PGT          
Sbjct: 4342 EQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGT---------- 4391

Query: 1174 AVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTP 1233
                     TWI   L+T  +     G         +  P      + +L        T 
Sbjct: 4392 ---------TWILTELTTAATTTAATG--------PTATPSSTPGTTWILTELTTTATTT 4434

Query: 1234 TPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQ-TTGTPAVTSTSYSQYRE 1292
              T ++ + +  PG  +    P    T      S A+    Q T GTP V++T+ +    
Sbjct: 4435 ASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT---- 4490

Query: 1293 KPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHS 1352
             P++   ++ PSS            PG A   T +P L ST       P       +P S
Sbjct: 4491 -PTVTSSKATPSSS-----------PGTA---TALPALRST----ATTPTATSFTAIPSS 4531

Query: 1353 HPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAV 1412
                   ++S  + P   T  T T +ST  + HT   S     +   +  T      S+ 
Sbjct: 4532 SLGTTWTRLSQTTTPT-ATMSTATPSSTPETVHT---STVLTATATTTGATGSVATPSST 4587

Query: 1413 PGPGDRKTGIPTLPSTFYSHT--EKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTP 1470
            PG     T +PT  +T ++ T    PG+        +  P   +  +  P     T    
Sbjct: 4588 PGTA-HTTKVPTTTTTGFTATPSSSPGT--------ALTPPVWISTTTTPTTTTPTTSGS 4638

Query: 1471 TVTS---PSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSP-SYSQ 1526
            TVT    P ++   + +         G +   S     +  P   TT A TIT+  S + 
Sbjct: 4639 TVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTN 4698

Query: 1527 HRAKSGSFYQLALLGSQIPEEAL---RVSSAPGPADQTTGIPTITSTS 1571
              +  G+     +L S     A    + +S+  P   TT +P +TST+
Sbjct: 4699 PSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATT-LPVLTSTA 4745



 Score = 50.8 bits (120), Expect = 3e-05
 Identities = 95/431 (22%), Positives = 150/431 (34%), Gaps = 33/431 (7%)

Query: 1279 TPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHT 1338
            TPA +ST+ +      + +    L ++  T E+   +A P      T I   PST  + T
Sbjct: 3677 TPATSSTA-TPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVT 3735

Query: 1339 EKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLP 1398
               G         S  T  + + +  +  V  T  TPTVTS+  +  +   +     +L 
Sbjct: 3736 VPTG---------STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR 3786

Query: 1399 GSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSV 1458
             +  T  A + +A+P      T       T  S T  P +      P S  PE A   +V
Sbjct: 3787 STATTPTATSFTAIPSSSLGTTW------TRLSQTTTPTATMSTATP-SSTPETAHTSTV 3839

Query: 1459 APGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPG-----PVGQT 1513
                   T  T +V +PSS+    P   +    P       ++  S +PG     PV  +
Sbjct: 3840 LTTTATTTRATGSVATPSST----PGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWIS 3895

Query: 1514 TGAPTITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGI-PTITSTSY 1572
            T     TS S     +  G+ +   +L +     A    + P  + QT+G  P++ +T+ 
Sbjct: 3896 TTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTAT 3955

Query: 1573 SFGEKPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKP----ITF 1628
            +           + P        L  +  +      T  P+  LG++     P     T 
Sbjct: 3956 TITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTH 4015

Query: 1629 YRQALLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQT--LSDSHLP 1686
             R     SP        SA  G       T P   TS++           T  LS  H  
Sbjct: 4016 GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPS 4075

Query: 1687 EEALKVPPVPG 1697
                + PP PG
Sbjct: 4076 SRTTESPPSPG 4086



 Score = 49.7 bits (117), Expect = 6e-05
 Identities = 201/1013 (19%), Positives = 313/1013 (30%), Gaps = 176/1013 (17%)

Query: 835  ALKVSAVSGPADGKTGTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGP 894
            A   +A +G     + TP         +S    P+A   +   +S     A  + ++   
Sbjct: 3002 AATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSS-PRTATTLPVLTST 3060

Query: 895  GDQKTGIPSAPSSFYSHREKPIIFSQQTLP----DFLFPEEALKVSAVS-VLAAQKTGTP 949
              + T     P   ++      +  Q T P      + P    + +  S VL  + T T 
Sbjct: 3061 ATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTR 3120

Query: 950  TVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPG--------LTDQKTVPTPTVPS 1001
              SS S   S   + +   EL  +     +   +A P         LT+  T  T TVP+
Sbjct: 3121 ATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPT 3180

Query: 1002 GSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLY 1061
            GS +               + AT   LKV T            A  SSS       +   
Sbjct: 3181 GSTATASS-----------TRATAGTLKVLTSTATTPTVISSRATPSSS----PGTATAL 3225

Query: 1062 PQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEA 1121
            P + S +  P  +  V+A P      + +     T  SQ   P                A
Sbjct: 3226 PALRSTATTPTAT-SVTAIP------SSSLGTAWTRLSQTTTP---------------TA 3263

Query: 1122 LKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQ 1181
               +  P    +   T TV +T+ +  R   S+    + PGT       KV   T  G  
Sbjct: 3264 TMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGT---AHTTKVPTTTTTGFT 3320

Query: 1182 KTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYS 1241
             T                      + PG+ +        PV       T TPT   ++ +
Sbjct: 3321 AT--------------------PSSSPGTAL------TPPVW---ISTTTTPTTRGSTVT 3351

Query: 1242 HTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQS 1301
             +  PG  +   +     T  A           QT+GTP   +T+ +      S     S
Sbjct: 3352 PSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSS 3411

Query: 1302 LPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKI 1361
             P +         +A    A   TV    PS+    T  P V      P++  T     +
Sbjct: 3412 TPGTTPIPPVLTTTATTPAATSSTV---TPSSALGTTHTPPV------PNTTATTHGRSL 3462

Query: 1362 SVASEPVDQTTGTPTVTSTSYSQHTEKPS-IFYQQSLPGSHLTEEAKNVSAVPGPGDRKT 1420
              +S    +T  T   +    + H  +PS +        +  T+ +    + P P  R T
Sbjct: 3463 PPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTT 3522

Query: 1421 GIPTLP-STFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSF 1479
              P  P +T   HT           P        L  S    P+  T    T   P  ++
Sbjct: 3523 ESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPI--TTVVTTGCEPQCAW 3580

Query: 1480 GEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLAL 1539
             E     Y                   PGP G           +YS  RA  G+  +   
Sbjct: 3581 SEWLDYSYPM-----------------PGPSGG-------DFDTYSNIRAAGGAVCEQP- 3615

Query: 1540 LGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFG-----EKPIVNYKQAF-------- 1586
            LG +      R  + PG   +  G   +   S  FG      + +  +K  F        
Sbjct: 3616 LGLE-----CRAQAQPGVPLRELG--QVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 3668

Query: 1587 -PDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKV 1645
               GH P         S P    T  P+   G++ +    +T        +         
Sbjct: 3669 CNYGHCP---------STPATSSTATPSSTPGTTWI----LTKLTTTATTTESTGSTATP 3715

Query: 1646 SAAPG-------PADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPGP 1698
            S+ PG       P+   T T+P  ST+ ++        Q T    H+   A   P V   
Sbjct: 3716 SSTPGTTWILTEPSTTATVTVPTGSTATASS------TQATAGTPHVSTTA-TTPTVTSS 3768

Query: 1699 DAQKTETPSVSSSLYSYRE---KPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTV 1755
             A    +P  +++L + R     P      A+P S L     ++S    P      +ST 
Sbjct: 3769 KATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPT---ATMSTA 3825

Query: 1756 TSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSYS 1808
            T S    T   +         +  T      S+ PG A   T V T T+T ++
Sbjct: 3826 TPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTA-HTTKVPTTTTTGFT 3877



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 93/427 (21%), Positives = 143/427 (33%), Gaps = 25/427 (5%)

Query: 1279 TPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHT 1338
            TPA +ST+        + +    L ++  T E+   +A P      T I   PST  + T
Sbjct: 2420 TPATSSTAMPS-STPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVT 2478

Query: 1339 EKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLP 1398
               G         S  T  + + +  +  V  T  TPTVTS+  +  +   +     +L 
Sbjct: 2479 VPTG---------STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALR 2529

Query: 1399 GSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSV 1458
             +  T  A + +A+P      T       T  S T  P +      P S  PE     +V
Sbjct: 2530 STATTPTATSFTAIPSSSLGTTW------TRLSQTTTPTATMSTATP-SSTPETVHTSTV 2582

Query: 1459 APGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPG-PVGQTTGAP 1517
                   T  T +V +PSS+ G             G     S     A   PV  +T   
Sbjct: 2583 LTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTT 2642

Query: 1518 TITSPSYSQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGI-PTITSTSYSFGE 1576
              T  S     +  G+ +   +L +     A    + P  + QT+G  P++T+T+ +   
Sbjct: 2643 PTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITA 2702

Query: 1577 KPIVNYKQAFPDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKP----ITFYRQA 1632
                    + P        L  +  +      T  P+  LG++     P     T  R  
Sbjct: 2703 TGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSL 2762

Query: 1633 LLDSPLNKEVVKVSAAPGPADQKTETLPVHSTSYSNRGKPVIFYQQT--LSDSHLPEEAL 1690
               SP        SA  G       T P   TS++           T  LS  H      
Sbjct: 2763 SPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTT 2822

Query: 1691 KVPPVPG 1697
            + PP PG
Sbjct: 2823 ESPPSPG 2829



 Score = 47.0 bits (110), Expect = 4e-04
 Identities = 170/861 (19%), Positives = 275/861 (31%), Gaps = 125/861 (14%)

Query: 1230 TGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQ 1289
            T TPT   ++ + +  PG  +   +     T  A           QT+GTP   +T+ + 
Sbjct: 2083 TTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATT 2142

Query: 1290 YREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVL 1349
                 S     S P +         +A    A   TV    PS+    T  P V      
Sbjct: 2143 ITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTV---TPSSALGTTHTPPV------ 2193

Query: 1350 PHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPG-SHLTEEAKN 1408
            P++  T     +  +S    +T  T   +    + H  +PS     +L   +  T+ +  
Sbjct: 2194 PNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTP 2253

Query: 1409 VSAVPGPGDRKTGIPTLP-STFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTI 1467
              + P P  R T  P  P +T   HT           P        L  S    P+   +
Sbjct: 2254 ALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVV 2313

Query: 1468 GTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQH 1527
                      + G +P   + +     +           PGP G           +YS  
Sbjct: 2314 ----------TMGCEPQCAWSEWLDYSY---------PMPGPSGG-------DFDTYSNI 2347

Query: 1528 RAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFG-----EKPIVNY 1582
            RA  G+  +   LG +      R  + PG   +  G   +   S  FG      + +  +
Sbjct: 2348 RAAGGAVCEQP-LGLE-----CRAQAQPGVPLRELG--QVVECSLDFGLVCRNREQVGKF 2399

Query: 1583 KQAF---------PDGHLPEEALKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQAL 1633
            K  F           GH P         S P    T +P+   G++ +    +T      
Sbjct: 2400 KMCFNYEIRVFCCNYGHCP---------STPATSSTAMPSSTPGTTWI----LTELTTTA 2446

Query: 1634 LDSPLNKEVVKVSAAPG-------PADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLP 1686
              +         S+ PG       P+   T T+P  ST+ ++        Q T    H+ 
Sbjct: 2447 TTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASS------TQATAGTPHVS 2500

Query: 1687 EEALKVPPVPGPDAQKTETPSVSSSLYSYRE---KPIVFYQQALPDSELTQEALKVSAVP 1743
              A   P V    A    +P  +++L + R     P      A+P S L     ++S   
Sbjct: 2501 TTA-TTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTT 2559

Query: 1744 QPADQKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVT 1803
             P      +ST T S    T   +         +  T      S+ PG A   T V T T
Sbjct: 2560 TPT---ATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTA-HTTKVLTTT 2615

Query: 1804 STSYSHREKPIVSYQRELPHFTEAGLKILRVPGPADQKTGINILPSNSYPQREHSVISYE 1863
            +T ++          R LP      + I     P  +  G  + PS S P   H+     
Sbjct: 2616 TTGFTATPSSSPGTARTLP------VWISTTTTPTTR--GSTVTPS-SIPGTTHTPTVL- 2665

Query: 1864 QELPDLTEVTLKAIGVPGPADQKTG-------IQIASSSSYSNREKASIFHQQELPDV-- 1914
                  T V   ++  P  + Q +G            +++ S    +S      +P V  
Sbjct: 2666 --TTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT 2723

Query: 1915 ----TEEALNVFVVPGQGDRKTEIPTVP---LSYYSRREKPSVISQQELPDSHLTEEALK 1967
                T  A +  V P      T  P VP    + + R   PS         +  T   L 
Sbjct: 2724 TTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLG 2783

Query: 1968 VSPVSIPAEQKTGIPIGLSSSYSHSHKEKLKISTVHIPDDQKTEFPAATLSSYSQIEKPK 2027
             + ++ P+   +  P   + +  HS      +S+ H P  + TE P +  ++     +  
Sbjct: 2784 TTHITEPSTGTSHTPAATTGTTQHSTP---ALSSPH-PSSRTTESPPSPGTTTPGHTRAT 2839

Query: 2028 ISTVIGPNDQKTPSQTAFHSS 2048
              T       KT + T   SS
Sbjct: 2840 SRTTATATPSKTRTSTLLPSS 2860



 Score = 47.0 bits (110), Expect = 4e-04
 Identities = 115/537 (21%), Positives = 181/537 (33%), Gaps = 89/537 (16%)

Query: 591  PDSHLTEEALKVSAAPG----LADQTTGMSTLTSTSYSH--REKPGTFYQQELPESNLTE 644
            P +  T      S+ PG    L +QTT  +T  +T  +      PGT    ++  S  T 
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3034

Query: 645  EPLEVSAAPGPVEQKTG--IPTVSST-------SHSHVEDLLFFYRQTLPDGHLTDQALK 695
                 S A      +T   +P ++ST       S + +         TLP+   T  A  
Sbjct: 3035 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094

Query: 696  VSAVSGPADQKTGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKT 755
             +       + T T+TVL+T                A + +   +++  S+TPG     T
Sbjct: 3095 STIHPSSTPETTHTSTVLTTK---------------ATTTRATSSMSTPSSTPGTTWILT 3139

Query: 756  EIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHR 815
            E+    +++ +    P+         + +  E    + V  P    TG     SS  +  
Sbjct: 3140 ELTTAATTTAA--TGPTATPSSTPGTTWILTEPSTTATVTVP----TGSTATASSTRATA 3193

Query: 816  EKLLVFYQQA----LLDSHLPEEALKVSAVSGPADGKTG-TPAVTS-TSSASSSLGEKPS 869
              L V    A    ++ S     +   +A + PA   T  TP  TS T+  SSSLG   +
Sbjct: 3194 GTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWT 3253

Query: 870  AFYQQTLPNSHL-------TEEALKVSIV---PGPGDQKTGIPSAPSSFYSHREKPIIFS 919
               Q T P + +       T E +  S V        + TG  + PSS         + +
Sbjct: 3254 RLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPT 3313

Query: 920  QQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRES 979
              T      P  +   +    +    T TPT   +                        +
Sbjct: 3314 TTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGS------------------------T 3349

Query: 980  LKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQ 1039
            +  S+IPG T   TV T T  + +      PS   Q                T P     
Sbjct: 3350 VTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTS-------------GTPPSLTTT 3396

Query: 1040 KTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPST 1096
             T I A  S++ P     +   P VL+ +     +   +  P  A   T TP VP+T
Sbjct: 3397 ATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNT 3453



 Score = 47.0 bits (110), Expect = 4e-04
 Identities = 100/490 (20%), Positives = 168/490 (34%), Gaps = 55/490 (11%)

Query: 948  TPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPG--------LTDQKTVPTPTV 999
            TP  SS +   S   + +   +L  +    ES   +A P         LT+  T  T TV
Sbjct: 3677 TPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTV 3736

Query: 1000 PSGSFSHREKPSIFYQQEWPDSYATEKALKVS-----TGPGPADQKTEIPAVQSSSYPQR 1054
            P+GS +               + AT   +  S     + PG A   T +PA++S++    
Sbjct: 3737 PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTA---TALPALRSTATTPT 3793

Query: 1055 EKPSVLYPQV--------LSDSHLPEESLKVSAFPGPADQMTDTPAVPST---------- 1096
                   P          LS +  P  ++  +A P    +   T  V +T          
Sbjct: 3794 ATSFTAIPSSSLGTTWTRLSQTTTPTATMS-TATPSSTPETAHTSTVLTTTATTTRATGS 3852

Query: 1097 FYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFH 1156
              +    PG  +   +P +      +  S +PG A     TP V  ++ +      S   
Sbjct: 3853 VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTAR----TPPVWISTTTTPTTSGSTVT 3908

Query: 1157 QQALPGT-HIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTL---PGSHI 1212
              ++PGT H P      +     G+  T      S+  +    P +    T     GS  
Sbjct: 3909 PSSVPGTTHTPTVLTTTTTTVATGSMAT----PSSSTQTSGTPPSLITTATTITATGSTT 3964

Query: 1213 -PEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASE 1271
             P      +P+         TP  TS++ + +   G  +   +P+   T     +S +S 
Sbjct: 3965 NPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSP 4024

Query: 1272 PVDQTTGTPAVTSTSYSQYREKPSIFYQQS-LPSSHLTEEAKNVSAVPGPADQKTVIPIL 1330
               +T  T A + T  + +  +PS     +   ++  T+ +    + P P+ + T  P  
Sbjct: 4025 HTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPS 4084

Query: 1331 P-STFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKP 1389
            P +T   HT           P    T   L  S  S P+     T  VT+    Q     
Sbjct: 4085 PGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPI-----TTVVTTGCEPQCAWSE 4139

Query: 1390 SIFYQQSLPG 1399
             + Y   +PG
Sbjct: 4140 WLDYSYPMPG 4149



 Score = 45.1 bits (105), Expect = 0.002
 Identities = 91/404 (22%), Positives = 138/404 (34%), Gaps = 29/404 (7%)

Query: 1303 PSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKIS 1362
            PS+  T      S+ PG     T I   P+T  + T   G         + PT   L+ +
Sbjct: 1889 PSTPATSSTATPSSTPGT----TWILTKPTTTATTTASTG-------STATPTS-TLRTA 1936

Query: 1363 VASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGI 1422
               + +  T  TPTVTS+  +  +   +     +L  +  T  A +V+ +P      T  
Sbjct: 1937 PPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTW- 1995

Query: 1423 PTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEK 1482
                 T  S T  P +      P S  PE A   +V       T  T +V +PSS+ G  
Sbjct: 1996 -----TRLSQTTTPTATMSTATP-SSTPETAHTSTVLTATATTTGATGSVATPSSTPGTA 2049

Query: 1483 PIVIYKQAFPEGH--LPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFYQLALL 1540
                       G    P  S   ++ P     TT  PT T  S     +  G+ +   +L
Sbjct: 2050 HTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPT-TRGSTVTPSSIPGTTHTATVL 2108

Query: 1541 GSQIPEEALRVSSAPGPADQTTGI-PTITSTSYSFGEKPIVNYKQAFPDGHLPEEALKVS 1599
             +     A    + P  + QT+G  P++T+T+ +           + P        L  +
Sbjct: 2109 TTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTT 2168

Query: 1600 IVSGPTEKKTDIPAGPLGSSALGEKP----ITFYRQALLDSPLNKEVVKVSAAPGPADQK 1655
              +      T  P+  LG++     P     T  R     SP        SA  G     
Sbjct: 2169 ATTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTT 2228

Query: 1656 TETLPVHSTSYSNRGKPVIFYQQT--LSDSHLPEEALKVPPVPG 1697
              T P   TS++           T  LS  H      + PP PG
Sbjct: 2229 HITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPG 2272



 Score = 42.7 bits (99), Expect = 0.007
 Identities = 100/490 (20%), Positives = 153/490 (31%), Gaps = 88/490 (17%)

Query: 948  TPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPG--------LTDQKTVPTPTV 999
            TP  SS +   S   + +   EL  +    ES   +A P         LT+  T  T TV
Sbjct: 2420 TPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTV 2479

Query: 1000 PSGSFSHREKPSIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSV 1059
            P+GS                   AT  + + + G          P V SS       P  
Sbjct: 2480 PTGST------------------ATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGT 2521

Query: 1060 LYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQREKPGIFYQQTLPESHLPK 1119
                    + LP  +L+ +A    A   T   A+PS+            Q T P + +  
Sbjct: 2522 A-------TALP--ALRSTATTPTATSFT---AIPSSSLGTTWTR--LSQTTTPTATMS- 2566

Query: 1120 EALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPG 1179
                 +  P    +   T TV +T+ +      S+    + PGT       KV   T  G
Sbjct: 2567 -----TATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGT---AHTTKVLTTTTTG 2618

Query: 1180 NQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSAS 1239
               T                             P  +   +  L      T TPT   ++
Sbjct: 2619 FTAT-----------------------------PSSSPGTARTLPVWISTTTTPTTRGST 2649

Query: 1240 YSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQ 1299
             + +  PG  +   +     T  A           QT+GTP   +T+ +      S    
Sbjct: 2650 VTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP 2709

Query: 1300 QSLPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEKPGVFYQQVLPHSHPTEEAL 1359
             S P +         +A    A   TV    PS+    T  P V      P++  T    
Sbjct: 2710 SSTPGTTPIPPVLTTTATTPAATSSTV---TPSSALGTTHTPPV------PNTTATTHGR 2760

Query: 1360 KISVASEPVDQTTGTPTVTSTSYSQHTEKPSIFYQQS-LPGSHLTEEAKNVSAVPGPGDR 1418
             +S +S    +T  T   + T  + H  +PS     +    +  T+ +    + P P  R
Sbjct: 2761 SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSR 2820

Query: 1419 KTGIPTLPST 1428
             T  P  P T
Sbjct: 2821 TTESPPSPGT 2830



 Score = 41.2 bits (95), Expect = 0.022
 Identities = 100/445 (22%), Positives = 153/445 (34%), Gaps = 66/445 (14%)

Query: 496  SGITTTPVDSDIGSHLSLSLEDLSQLAVSSPLETTTGQHTDTLNQKTLADTHL--TEETL 553
            +G T TP  S  G+   L+ E  +   V+ P  +T    T +  Q T    H+  T  T 
Sbjct: 3709 TGSTATP-SSTPGTTWILT-EPSTTATVTVPTGSTA---TASSTQATAGTPHVSTTATTP 3763

Query: 554  KVTAIPEPADQKTATPTVLSSSHSHRGKPSIFYQQGLPDSHL-----------TEEALKV 602
             VT+          T T L +  S    P+      +P S L           T  A   
Sbjct: 3764 TVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMS 3823

Query: 603  SAAPGLADQTTGMST-LTSTSYSHR---------EKPGTFYQQELPESNLTEEPLEVSAA 652
            +A P    +T   ST LT+T+ + R           PGT +  ++P +  T   +  S++
Sbjct: 3824 TATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSS 3883

Query: 653  PGPVE------QKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQK 706
            PG           T  PT S ++ +        +  T+     T  A    A    + Q 
Sbjct: 3884 PGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQT 3943

Query: 707  TGTATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYS 766
            +GT   L T  +     G               + T  S+TPG     T IP V +++ +
Sbjct: 3944 SGTPPSLITTATTITATG---------------STTNPSSTPGT----TPIPPVLTTTAT 3984

Query: 767  QREKPS--ILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQ 824
                 S  +     L  +H P        V        G    PSS ++ R         
Sbjct: 3985 TPAATSSTVTPSSALGTTHTPP-------VPNTTATTHGRSLSPSSPHTVRTAWTSATSG 4037

Query: 825  ALLDSHLPEEALKVSAVSGPADGKT--GTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLT 882
             L  +H+ E +   S       G T   TPA++S   +S +    PS     T P     
Sbjct: 4038 TLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSP--GTTTPGHTTA 4095

Query: 883  EEALKVSIVPGPGDQKTGIPSAPSS 907
                  +  P      T +PS+P+S
Sbjct: 4096 TSRTTATATPSKTRTSTLLPSSPTS 4120



 Score = 40.4 bits (93), Expect = 0.037
 Identities = 154/806 (19%), Positives = 259/806 (32%), Gaps = 117/806 (14%)

Query: 638  PESNLTEEPLEVSAAPGPVEQKTGIPTVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVS 697
            P +  T      S+ PG     T + T ++T+ S           T         A    
Sbjct: 4232 PSTPATSSTAMPSSTPGTTWILTELTTTATTTAST--------GSTATPSSTPGTAPPPK 4283

Query: 698  AVSGPADQKTGT---ATVLSTPHSHREKPGIFYQQEFADSHQTEETLTKVSATPGPADQK 754
             ++ PA   T T   AT  S+P +    P +        S  T+ T T V  TP P+   
Sbjct: 4284 VLTSPATTPTATSSKATSSSSPRTATTLPVL-------TSTATKSTATSV--TPIPSSTL 4334

Query: 755  TEIPAVQSSSYSQREKPSILYPQDLADSHLPEEGLKVSAVAGPADQKTGLPT-VPSSAYS 813
                 +   + +     S ++P    ++      L   A    A   T  P+  P + + 
Sbjct: 4335 GTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWI 4394

Query: 814  HREKLLVFYQQALLDSHLPEEALKVSAVSGPADGKTGTPAVT-----STSSASSSLGEKP 868
              E                  A   +A +GP    + TP  T      T++A+++     
Sbjct: 4395 LTELTT---------------AATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGS 4439

Query: 869  SAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYSHREKPIIFSQQTLPDFLF 928
            +A    T   + +  E    + V  P    TG  +  SS  +    P + +  T P    
Sbjct: 4440 TATPSSTPGTTWILTEPSTTATVTVP----TGSTATASSTQATAGTPHVSTTATTPT--- 4492

Query: 929  PEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQELPDSDLPRESLKMSAIPGL 988
                  V++     +   GT T      S +   +      +P S L     ++S     
Sbjct: 4493 ------VTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLS----- 4541

Query: 989  TDQKTVPTPTVPSGSFSHREKP---SIFYQQEWPDSYATEKALKVSTGPGPADQKTEIPA 1045
              Q T PT T+ + + S   +    S         + AT      S+ PG A   T++P 
Sbjct: 4542 --QTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTA-HTTKVPT 4598

Query: 1046 VQSSSY---PQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPAVPSTFYSQRE 1102
              ++ +   P     + L P V            +S    P    T TP    +  +   
Sbjct: 4599 TTTTGFTATPSSSPGTALTPPVW-----------ISTTTTPT---TTTPTTSGSTVTPSS 4644

Query: 1103 KPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKPSIFHQQALPG 1162
             PG  +   +  +     A      P  + Q +GTP   +T+ +      S  +  + PG
Sbjct: 4645 IPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPG 4704

Query: 1163 THIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGSHIPEEAQKVSPV 1222
            T  P      S  T P    +                          S  P  A  + PV
Sbjct: 4705 T-TPITPVLTSTATTPAATSS----------------------KATSSSSPRTATTL-PV 4740

Query: 1223 LGPADQKTGTPT-PTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVASEPVDQTTGTPA 1281
            L      T T T  T+ S++      ++    +P    T  +   ++ +    +TT T  
Sbjct: 4741 L------TSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTST 4794

Query: 1282 VTSTSYSQYREKPSIFYQQS-LPSSHLTEEAKNVSAVPGPADQKTVIPILPSTFYSHTEK 1340
            V +T+ +  R   S     S L ++ +  E    +           +   P T +  TE 
Sbjct: 4795 VLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTE- 4853

Query: 1341 PGVFYQQVLPHSHPTEEALKISVASEPVDQTT--GTPTVTSTSYSQHTEKPSIFYQQSLP 1398
            P      ++P       +  +  A  P   TT    PT T+++    +   +      LP
Sbjct: 4854 PSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLP 4913

Query: 1399 GSHLTEEAKNVSAVPGPGDRKTGIPT 1424
             S  T     VS+      R TG P+
Sbjct: 4914 SSLPTFSVSTVSSSVLTTLRPTGFPS 4939



 Score = 38.9 bits (89), Expect = 0.11
 Identities = 206/1021 (20%), Positives = 334/1021 (32%), Gaps = 183/1021 (17%)

Query: 851  TPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYS 910
            TPA +ST+  SS+ G   + +    L  +  T E+   +  P      T I + PS+   
Sbjct: 2420 TPATSSTAMPSSTPG---TTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTT-- 2474

Query: 911  HREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKT-GTPTVSSNSHSHSEKSSVFYQQE 969
                    +  T+P           S  +  + Q T GTP VS+ + + +  SS      
Sbjct: 2475 --------ATVTVPTG---------STATASSTQATAGTPHVSTTATTPTVTSSKATPFS 2517

Query: 970  LPDSDLPRESLKMSAIPGLTDQKTVPTPT----VPSGSF-------SHREKPSIFYQQEW 1018
             P +         +A+P L    T PT T    +PS S        S    P+       
Sbjct: 2518 SPGT--------ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT 2569

Query: 1019 PDSYA-TEKALKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKV 1077
            P S   T     V T        T   A  SS+        VL       +  P  S   
Sbjct: 2570 PSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSS--- 2626

Query: 1078 SAFPGPADQM------TDTPAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLA 1131
               PG A  +      T TP    +  +    PG  +  T+  +     A      P  +
Sbjct: 2627 ---PGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSS 2683

Query: 1132 DQKTGTPTVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLST 1191
             Q +GTP   +T+ +      S  +  + PGT                   T IP VL+T
Sbjct: 2684 TQTSGTPPSLTTTATTITATGSTTNPSSTPGT-------------------TPIPPVLTT 2724

Query: 1192 FYSQREKPGIFYQQTLPGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQ 1251
                                                    TP  TS++ + +   G  + 
Sbjct: 2725 -------------------------------------TATTPAATSSTVTPSSALGTTHT 2747

Query: 1252 QVLPDNHPTEEALKISVASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQS-LPSSHLTEE 1310
              +P+   T     +S +S    +T  T A + T  + +  +PS     +   ++  T+ 
Sbjct: 2748 PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 2807

Query: 1311 AKNVSAVPGPADQKTVIPILP-STFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVD 1369
            +    + P P+ + T  P  P +T   HT           P    T   L  S  S P+ 
Sbjct: 2808 STPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPI- 2866

Query: 1370 QTTGTPTVTSTSYSQHTEKPSIFYQQSLPG---------SHLTEEAKNV----------- 1409
                T  VT     Q      + Y   +PG         S++      V           
Sbjct: 2867 ----TTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRA 2922

Query: 1410 SAVPGPGDRKTGIPTLPSTFYS----HTEKPGSFYQQVLPHSHLPEEALEVSVAPG-PVD 1464
             A PG   R+ G     S  +     + E+ G F  ++  +  +          P  P  
Sbjct: 2923 QAQPGVPLRELGQVVECSLDFGLVCRNREQVGKF--KMCFNYEIRVFCCNYGHCPSTPAT 2980

Query: 1465 QTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSY 1524
             +  TP+ T  ++    +           G     S     AP P   T+   T T+P+ 
Sbjct: 2981 SSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTS---TATTPTA 3037

Query: 1525 SQHRAKSGSFYQLALLGSQIPEEALRVSSAPGPADQTTGIPTIT-STSYSFGEK---PIV 1580
            +  +A S S  + A   + +P   L  ++    A   T IP+ T  T+ +  E+   P+ 
Sbjct: 3038 TSSKATSSSSPRTA---TTLP--VLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMA 3092

Query: 1581 NYKQAFPDGHLPEEALKVSIVS--GPTEKKTDIPAGPLGSSALGEKPI-TFYRQALLDSP 1637
                  P    PE     ++++    T + T   + P  SS  G   I T    A   + 
Sbjct: 3093 TMSTIHPSS-TPETTHTSTVLTTKATTTRATSSMSTP--SSTPGTTWILTELTTAATTTA 3149

Query: 1638 LNKEVVKVSAAPG-------PADQKTETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEAL 1690
                    S+ PG       P+   T T+P  ST+ ++  +      + L+ +       
Sbjct: 3150 ATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTST------A 3203

Query: 1691 KVPPVPGPDAQKTETPSVSSSLYSYRE---KPIVFYQQALPDSELTQEALKVSAVPQPAD 1747
              P V    A  + +P  +++L + R     P      A+P S L     ++S    P  
Sbjct: 3204 TTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPT- 3262

Query: 1748 QKTGLSTVTSSFYSHTEKPNISYQQELPDSHLTEEALKVSNVPGPADQKTGVSTVTSTSY 1807
                +ST T S    T   +         +  T      S+ PG A   T V T T+T +
Sbjct: 3263 --ATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTA-HTTKVPTTTTTGF 3319

Query: 1808 S 1808
            +
Sbjct: 3320 T 3320



 Score = 37.4 bits (85), Expect = 0.31
 Identities = 103/516 (19%), Positives = 168/516 (32%), Gaps = 86/516 (16%)

Query: 851  TPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKTGIPSAPSSFYS 910
            TPA +ST++ SS+    P   +  T P +  T  A   S        +T  P  P    +
Sbjct: 1891 TPATSSTATPSST----PGTTWILTKPTTTATTTASTGSTATPTSTLRTAPP--PKVLTT 1944

Query: 911  HREKPIIFSQQTLPDFLFPEEALKVSAVSVLAAQKTGTPTVSSNSHSHSEKSSVFYQQEL 970
                P + S +  P    P  A  + A+   A   T T      S S     +   Q   
Sbjct: 1945 TATTPTVTSSKATPSSS-PGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTT 2003

Query: 971  PDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKALKV 1030
            P + +   +   S+ P      TV T T  +                     AT      
Sbjct: 2004 PTATM--STATPSSTPETAHTSTVLTATATTTG-------------------ATGSVATP 2042

Query: 1031 STGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDT 1090
            S+ PG A   T++P   ++ +                +  P  S   +  P      T T
Sbjct: 2043 SSTPGTA-HTTKVPTTTTTGF----------------TATPSSSPGTALTPPVWISTTTT 2085

Query: 1091 PAVPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHRE 1150
            P    +  +    PG  +  T+  +     A      P  + Q +GTP   +T+ +    
Sbjct: 2086 PTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITA 2145

Query: 1151 KPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYSQREKPGIFYQQTLPGS 1210
              S  +  + PGT         +A T      T  P                    L  +
Sbjct: 2146 TGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTP-----------------SSALGTT 2188

Query: 1211 HIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKISVAS 1270
            H P     ++   G +   +   T  +A  S T         +L   H TE +   +V S
Sbjct: 2189 HTPPVPNTMATTHGRSLPPSSPHTVRTAWTSAT-------SGILGTTHITEPS---TVTS 2238

Query: 1271 EPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPS------SHLTEEAK-NVSAVPGPADQ 1323
              +  TTGT   ++ + S     PS    +S PS       H T  ++   +A P     
Sbjct: 2239 HTLAATTGTTQHSTPALSS--PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRT 2296

Query: 1324 KTVIPILP-----STFYSHTEKPGVFYQQVLPHSHP 1354
             T++P  P     +T  +   +P   + + L +S+P
Sbjct: 2297 STLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYP 2332



 Score = 37.4 bits (85), Expect = 0.31
 Identities = 93/428 (21%), Positives = 140/428 (32%), Gaps = 85/428 (19%)

Query: 529  TTTGQHTDTLNQKTLADTHLTEETLKV---TAIPEPADQKTATP-------TVLSSSHSH 578
            TT      T +  T + T  T  TLKV   TA         ATP       T L +  S 
Sbjct: 3172 TTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRST 3231

Query: 579  RGKPSIFYQQGLPDSHL-----------TEEALKVSAAPGLADQTTGMST-LTSTSYSHR 626
               P+      +P S L           T  A   +A P    +T   ST LT+T+ + R
Sbjct: 3232 ATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTR 3291

Query: 627  ---------EKPGTFYQQELPESNLTEEPLEVSAAPG--------------PVEQKTGIP 663
                       PGT +  ++P +  T      S++PG              P  + + + 
Sbjct: 3292 ATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVT 3351

Query: 664  TVSSTSHSHVEDLLFFYRQTLPDGHLTDQALKVSAVSGPADQKTGTATVLSTPHSHREKP 723
              S    +H   +L     T+  G +   +   +  SG     T TAT ++   S     
Sbjct: 3352 PSSIPGTTHTATVLTTTTTTVATGSMATPS-SSTQTSGTPPSLTTTATTITATGS----- 3405

Query: 724  GIFYQQEFADSHQTEETLTKVSATPGPADQKTEIPAVQSSSYSQREKPS--ILYPQDLAD 781
                              T  S+TPG     T IP V +++ +     S  +     L  
Sbjct: 3406 -----------------TTNPSSTPG----TTPIPPVLTTTATTPAATSSTVTPSSALGT 3444

Query: 782  SHLPEEGLKVSAVAGPADQKTGLPTVPSSAYSHREKLLVFYQQALLDSHLPEEALKVSAV 841
            +H P        V        G    PSS ++ R          L  +H+ E +   S  
Sbjct: 3445 THTP-------PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHT 3497

Query: 842  SGPADGKT--GTPAVTSTSSASSSLGEKPSAFYQQTLPNSHLTEEALKVSIVPGPGDQKT 899
                   T   TPA++S   +S +    PS     T P           +  P      T
Sbjct: 3498 PAATTSTTQHSTPALSSPHPSSRTTESPPSP--GTTTPGHTRGTSRTTATATPSKTRTST 3555

Query: 900  GIPSAPSS 907
             +PS+P+S
Sbjct: 3556 LLPSSPTS 3563


>gi|30089948 protein phosphatase 1E [Homo sapiens]
          Length = 755

 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 50/176 (28%), Positives = 73/176 (41%), Gaps = 24/176 (13%)

Query: 2   EPEDLPWPGELEEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSDSHY 61
           EPE  P P    E E E E E E  E EAA A+     +        EE  +E D +   
Sbjct: 30  EPEPEPEPEPEPEPESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEGDQEQDPE--- 86

Query: 62  GPQHLESIDDEEDEEAKAWLQAHPGRI--------LPPLSPPQHRYSEGERTSLEKIVPL 113
            P+   +++ EE+EE  A   A PG          LPPL P     S  ER + E++   
Sbjct: 87  -PEEEAAVEGEEEEEGAATAAAAPGHSAVPPPPPQLPPLPPLPRPLS--ERITREEVEGE 143

Query: 114 TCHVWQQIVYQGNSRTQISDTNVVCLETTAQRGSGDD--QKTESWHCLPQEMDSSQ 167
           +  +  Q +Y+ N  +         L     R + D+  Q   S H +P+E D ++
Sbjct: 144 SLDLCLQQLYKYNCPS--------FLAAALARATSDEVLQSDLSAHYIPKETDGTE 191


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 51.6 bits (122), Expect = 2e-05
 Identities = 130/564 (23%), Positives = 188/564 (33%), Gaps = 107/564 (18%)

Query: 1423 PTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVS-------VAPGPVDQTIGTPTVTSP 1475
            PT P    S    P     + LP S LPE AL +S       ++P P +  +  P  +SP
Sbjct: 457  PTSPPPEASRLSPP----PEELPASPLPE-ALHLSRPLEESPLSPPPEESPLSPPPESSP 511

Query: 1476 SSSFGEKPIVIYKQAFPEGHLPEESLKVSVAPGPVGQTTGAPTITSPSYSQHRAKSGSFY 1535
             S   E P+     + PE   P  +L+  ++P P       P   SP             
Sbjct: 512  FSPLEESPL-----SPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE------ 560

Query: 1536 QLALLGSQIPEEALRVSSAPGPADQTTGIPTITSTSYSFGEKPIVNYKQAFPDGHLPEEA 1595
                L +  P EA R+S  P P +     P   S        P     + FP        
Sbjct: 561  ----LPTSPPPEASRLS--PPPEESPMSPPPEESPM-----SPPPEASRLFP-------P 602

Query: 1596 LKVSIVSGPTEKKTDIPAGPLGSSALGEKPITFYRQALLDSPLNKEVVKVSAAPGPADQK 1655
             + S +S P E+    P  P  +S L   P         DSP++    +   +P P   +
Sbjct: 603  FEESPLSPPPEESPLSP--PPEASRLSPPP--------EDSPMSPPPEESPMSPPPEVSR 652

Query: 1656 TETLPVHSTSYSNRGKPVIFYQQTLSDSHLPEEALKVPPVPGPDAQKTETPSVSSSLYSY 1715
               LPV S                   S  PEE+   P  P P+   T  P  +S L   
Sbjct: 653  LSPLPVVSRL-----------------SPPPEES---PLSPPPEESPTSPPPEASRLSPP 692

Query: 1716 REKPIVFYQQALPDSELTQEALKVSAVPQPADQKTGLSTVTSSFYSHTEKPNISYQQELP 1775
             E           DS  +       A P P D    L    S      E+P +  + E P
Sbjct: 693  PE-----------DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGP 741

Query: 1776 DSHLTEEALKVSNVPGPADQKTGVSTVTSTSYSHREKPIVSYQRELPHFTEAGLKILRVP 1835
              HL+    +    P P                  E+P +S Q E PH +    +     
Sbjct: 742  --HLSPRPEEPHLSPRP------------------EEPHLSPQAEEPHLSPQPEEPCLCA 781

Query: 1836 GPADQKTGINILPSNSYPQREHSVISYEQELPDLTEVTLKAIGVPGPADQKTGIQIASSS 1895
             P +          +  PQ E   +S + E P L+ V  +    P P +     Q     
Sbjct: 782  VPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPC 841

Query: 1896 SYSNREKASIFHQQELPDVTEEALNVFVVPGQGDRKTEIPTVP----LSYYSRREKPSVI 1951
                 E++ +  + E P ++         PGQ     E+P  P     S      +P++ 
Sbjct: 842  LSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALS 901

Query: 1952 SQQELPDSHLTEEALKVSPVSIPA 1975
               E P S L EE L +SP   P+
Sbjct: 902  EPGEPPLSPLPEE-LPLSPSGEPS 924



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 114/500 (22%), Positives = 170/500 (34%), Gaps = 58/500 (11%)

Query: 1034 PGPADQKTEIPAVQSS-SYPQREKPSVLYPQVLSDSHLPEESLKVSAFPGPADQMTDTPA 1092
            P P +  T  P   S  S P  E P+   P+ L  S   EES      P P +     P 
Sbjct: 451  PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEES---PLSPPPEESPLSPPP 507

Query: 1093 VPSTFYSQREKPGIFYQQTLPESHLPKEALKISVAPGLADQKTGTPTVTSTSYSQHREKP 1152
              S F    E P      + PE   P  AL+  ++P         P   S       E P
Sbjct: 508  ESSPFSPLEESP-----LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP 562

Query: 1153 SIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIP-----RVLSTFYSQREKPGIFYQQTL 1207
            +    +A   +  PEE    S ++ P  +    P     R+   F      P        
Sbjct: 563  TSPPPEASRLSPPPEE----SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS 618

Query: 1208 PGSHIPEEAQKVSPVLGPADQKTGTPTPTSASYSHTEKPGIFYQQVLPDNHPTEEALKIS 1267
            P    P EA ++SP   P +    +P P  +  S    P +     LP         + S
Sbjct: 619  P----PPEASRLSP---PPEDSPMSPPPEESPMS--PPPEVSRLSPLPVVSRLSPPPEES 669

Query: 1268 VASEPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVI 1327
              S P +++  +P   ++  S   E          P+S   E++    A P P D    +
Sbjct: 670  PLSPPPEESPTSPPPEASRLSPPPEDS--------PTSPPPEDSP---ASPPPEDSLMSL 718

Query: 1328 PILPSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTE 1387
            P+  S      E+P +  +   PH  P  E   +S   E   +   +P       S   E
Sbjct: 719  PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPE---EPHLSPQAEEPHLSPQPE 775

Query: 1388 KPSIFYQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHS 1447
            +P +      P  HL+ +A+     P P +      T         E+P    Q     S
Sbjct: 776  EPCLCAVPEEP--HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQP--EES 831

Query: 1448 HLPEEALEVSVAPGPVDQTIGTPTVTSPSSSFGEKPIVIYKQAFPE--GHLP-EESLKVS 1504
            HL  ++ E  ++P P +  +       P S   EKP        PE  G  P  E L + 
Sbjct: 832  HLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP--------PEEPGQCPAPEELPLF 883

Query: 1505 VAPG--PVGQTTGAPTITSP 1522
              PG   +    G P ++ P
Sbjct: 884  PPPGEPSLSPLLGEPALSEP 903



 Score = 34.3 bits (77), Expect = 2.7
 Identities = 150/633 (23%), Positives = 217/633 (34%), Gaps = 84/633 (13%)

Query: 968  QELPDSDLPRESLKMSAIPGLTDQKTVPTPTVPSGSFSHREKPSIFYQQEWPDSYATEKA 1027
            ++ P S  P ES  MS  P ++  +  P P V   S    E P     +E P S   E +
Sbjct: 631  EDSPMSPPPEES-PMSPPPEVS--RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687

Query: 1028 LKVSTGPGPADQKTEIPAVQSSSYPQREKPSVLYPQVLSDSHL---PEESLKVSAFPGPA 1084
                  P P D  T  P   S + P  E   +  P  L +S L   PEE        GP 
Sbjct: 688  ---RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLP--LEESPLLPLPEEPQLCPRSEGP- 741

Query: 1085 DQMTDTPAVPSTFYSQREKPGIFYQQTLPE-SHLPKEALKISVA--PGLADQKTG---TP 1138
              ++  P  P     + E+P +  Q   P  S  P+E    +V   P L+ Q  G   +P
Sbjct: 742  -HLSPRPEEPH-LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSP 799

Query: 1139 TVTSTSYSQHREKPSIFHQQALPGTHIPEEAQKVSAVTGPGNQKTWIPRVLSTFYS-QRE 1197
                   S   E+P   H   +P         + S ++    +    PR   +  S + E
Sbjct: 800  QPEELHLSPQTEEP---HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELE 856

Query: 1198 KPGIFYQQTLPGSH-----IPEEAQ--------KVSPVLG-PADQKTG----TPTPTSAS 1239
            KP +  +   P         PEE           +SP+LG PA  + G    +P P    
Sbjct: 857  KPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELP 916

Query: 1240 YSHTEKPGIFYQQVLPDNHPTEEALKISVASEPV---------------DQTTGTPAVTS 1284
             S + +P +  Q + PD  P   +  I+ A+ P                D    +P    
Sbjct: 917  LSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAP 976

Query: 1285 TSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPILP--STFYSHTEKPG 1342
               +     P        P   +       S V GPA    + P+ P  S    H+  P 
Sbjct: 977  ILETPISPPPEANCTDPEPVPPMILPPSPGSPV-GPASPILMEPLPPQCSPLLQHSLVP- 1034

Query: 1343 VFYQQVLPHSHPTEEALKISVAS--EPVDQTTGTPTVTSTSYSQHTEKPSIFYQQSLPGS 1400
                Q  P S  +  AL +SV S   P+ +  G  +  +  +   TEK S   +   P  
Sbjct: 1035 ----QNSPPSQCSPPALPLSVPSPLSPIGKVVGV-SDEAELHEMETEKVS---EPECPAL 1086

Query: 1401 HLTEEAKNVSAVPGP-GDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSHLPEEALEVSVA 1459
                E    S +P P GD     P+ P+         G      L     P    E    
Sbjct: 1087 ----EPSATSPLPSPMGDLSCPAPS-PAPALDDFSGLGE-DTAPLDGIDAPGSQPEPGQT 1140

Query: 1460 PGPVDQTI-GTPTVTSPSSSFGEKPIVIY---KQAFPEGHLPE--ESLKVSVAPGPVGQT 1513
            PG +   + G+P +  P       P+ +Y   KQ   +G   E  E  +  VAP P    
Sbjct: 1141 PGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLI 1200

Query: 1514 TGAPTITSPSYSQHRAKSGSFYQLALLGSQIPE 1546
                     + SQ  A +       LLGS  PE
Sbjct: 1201 KSDIVNEISNLSQGDASASFPGSEPLLGSPDPE 1233



 Score = 32.7 bits (73), Expect = 7.7
 Identities = 75/316 (23%), Positives = 114/316 (36%), Gaps = 57/316 (18%)

Query: 1213 PEEAQKVSPVLGPADQKTGTPTPTSASYSHT--EKPGIFYQQVLPDNHPTEEALKISVAS 1270
            PEE    SP+  P ++   +P P ++  S    E P     + L  + P EE    S  S
Sbjct: 444  PEE----SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEE----SPLS 495

Query: 1271 EPVDQTTGTPAVTSTSYSQYREKPSIFYQQSLPSSHLTEEAKNVSAVPGPADQKTVIPIL 1330
             P +++  +P   S+ +S   E P    ++S PS      A      P P       P+ 
Sbjct: 496  PPPEESPLSPPPESSPFSPLEESPLSPPEESPPS-----PALETPLSPPP----EASPLS 546

Query: 1331 PSTFYSHTEKPGVFYQQVLPHSHPTEEALKISVASEPVDQTTGTPTVTSTSYSQHTEKPS 1390
            P    S    P        P   PT    + S  S P +++  +P    +  S   E   
Sbjct: 547  PPFEESPLSPP--------PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR 598

Query: 1391 IF--YQQSLPGSHLTEEAKNVSAVPGPGDRKTGIPTLPSTFYSHTEKPGSFYQQVLPHSH 1448
            +F  +++S P S   EE+                P  P    S    P     +  P S 
Sbjct: 599  LFPPFEES-PLSPPPEES----------------PLSPPPEASRLSPP----PEDSPMSP 637

Query: 1449 LPEEALEVSVAPGP-VDQTIGTPTVTSPSSSFGEKPIVIYKQAFPEGHLPEESLKVSVAP 1507
             PEE+    ++P P V +    P V+  S    E P+    +  P    PE S    ++P
Sbjct: 638  PPEES---PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS---RLSP 691

Query: 1508 GPVGQTTGAPTITSPS 1523
             P    T  P   SP+
Sbjct: 692  PPEDSPTSPPPEDSPA 707


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score = 51.2 bits (121), Expect = 2e-05
 Identities = 31/70 (44%), Positives = 39/70 (55%), Gaps = 1/70 (1%)

Query: 11  ELEEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSD-SHYGPQHLESI 69
           E EEEEEEEEEEEEEEEEE  AAAA  + +V+         G E  +D S  G       
Sbjct: 751 EEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLA 810

Query: 70  DDEEDEEAKA 79
           DD+++   +A
Sbjct: 811 DDQKESRGRA 820



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 26/64 (40%), Positives = 34/64 (53%)

Query: 10  GELEEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSDSHYGPQHLESI 69
           G+ EEEEEEE+EEEEEE+EE         ++    EE EEEA   +      GP+   S 
Sbjct: 731 GKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSS 790

Query: 70  DDEE 73
           +  E
Sbjct: 791 EGSE 794



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 35/97 (36%), Positives = 44/97 (45%), Gaps = 30/97 (30%)

Query: 13  EEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSDSHYGPQHLESIDDE 72
           EEEEEEEE+EEEEEE+E               EE EEE   E            E  ++E
Sbjct: 733 EEEEEEEEDEEEEEEDE---------------EEEEEEEEEE------------EEEEEE 765

Query: 73  EDEEAKAWLQAHPGRILPPLSPPQHRYSEGERTSLEK 109
           E+EE +A      G +L P S      SEG   S ++
Sbjct: 766 EEEEEEAAAAVALGEVLGPRSGSS---SEGSERSTDR 799


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
           sapiens]
          Length = 631

 Score = 50.4 bits (119), Expect = 4e-05
 Identities = 53/186 (28%), Positives = 78/186 (41%), Gaps = 33/186 (17%)

Query: 2   EPEDLPWPGELEEEEEEEEEEEEEEEEEAAAAAAANVDDVVVVEEVEEEAGRELDSDSHY 61
           E E++   G  EEEEEEEEEEEEEEEEE               EE +  AG +    +H 
Sbjct: 116 EDEEIQEEGGEEEEEEEEEEEEEEEEEEE--------------EEEQPRAGPQGSGGNH- 160

Query: 62  GPQHLESIDDEEDEEAKAWLQAHPGRILPPLSPPQHRYSEGERTSLEKIVPLTCHVWQQI 121
                E    EED+  + W+ +    +  P         + +  S  + V   C   +  
Sbjct: 161 -----EQYSLEEDQALEEWVSSETSALPRPRWQVVTALHQRQLGSRPRFVYEACGA-RAF 214

Query: 122 VYQGNSRTQISDTNVVCLETT--AQRG-----SGDDQKTESWHCLPQ----EMDSSQTLD 170
           V +   + +++D +V C+ T    QRG     SGDD K   W  + Q      +S  T +
Sbjct: 215 VQRFRLQYRLAD-HVGCVNTVHFNQRGTRLASSGDDLKVIVWDWVRQRPVLNFESGHTNN 273

Query: 171 TSQTRF 176
             Q +F
Sbjct: 274 VFQAKF 279


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.126    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 174,898,947
Number of Sequences: 37866
Number of extensions: 9028057
Number of successful extensions: 54238
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 280
Number of HSP's successfully gapped in prelim test: 408
Number of HSP's that attempted gapping in prelim test: 38839
Number of HSP's gapped (non-prelim): 8863
length of query: 4169
length of database: 18,247,518
effective HSP length: 123
effective length of query: 4046
effective length of database: 13,590,000
effective search space: 54985140000
effective search space used: 54985140000
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 73 (32.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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