Guide to the Human Genome
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Search of human proteins with 156415998

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156415998 zinc finger protein 219 [Homo sapiens]
         (722 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156416026 zinc finger protein 219 [Homo sapiens]                  1519   0.0  
gi|156415998 zinc finger protein 219 [Homo sapiens]                  1519   0.0  
gi|156415996 zinc finger protein 219 [Homo sapiens]                  1519   0.0  
gi|7662092 zinc finger protein 536 [Homo sapiens]                     242   8e-64
gi|7662010 zinc finger protein 516 [Homo sapiens]                     199   7e-51
gi|148276998 zinc finger protein 628 [Homo sapiens]                   157   4e-38
gi|22749325 zinc finger protein 48 [Homo sapiens]                     137   5e-32
gi|116256460 zinc finger protein 775 [Homo sapiens]                   129   1e-29
gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]         124   3e-28
gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]         124   3e-28
gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]         124   3e-28
gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]         124   3e-28
gi|110681708 zinc finger protein 579 [Homo sapiens]                   118   2e-26
gi|14249488 zinc finger and SCAN domain containing 10 [Homo sapi...   117   4e-26
gi|48717241 zinc finger protein 425 [Homo sapiens]                    113   5e-25
gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]            112   9e-25
gi|154744870 zinc finger protein 574 [Homo sapiens]                   110   4e-24
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...   107   5e-23
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...   107   5e-23
gi|37622341 zinc finger protein 42 isoform 2 [Homo sapiens]           104   3e-22
gi|37622345 zinc finger protein 42 isoform 1 [Homo sapiens]           104   3e-22
gi|13376247 zinc finger protein 672 [Homo sapiens]                    101   2e-21
gi|46409310 zinc finger protein 467 [Homo sapiens]                     99   2e-20
gi|133922582 zinc finger protein 358 [Homo sapiens]                    97   4e-20
gi|38348236 zinc finger protein 497 [Homo sapiens]                     97   5e-20
gi|7657693 zinc finger protein 324 [Homo sapiens]                      97   5e-20
gi|34147544 zinc finger protein HIT-39 [Homo sapiens]                  96   2e-19
gi|24432013 zinc finger protein 668 [Homo sapiens]                     94   3e-19
gi|13376064 zinc finger protein 408 [Homo sapiens]                     94   3e-19
gi|221307573 zinc finger protein 275 [Homo sapiens]                    94   4e-19

>gi|156416026 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 1519 bits (3934), Expect = 0.0
 Identities = 722/722 (100%), Positives = 722/722 (100%)

Query: 1   MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60
           MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP
Sbjct: 1   MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60

Query: 61  VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL 120
           VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL
Sbjct: 61  VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL 120

Query: 121 LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER 180
           LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER
Sbjct: 121 LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER 180

Query: 181 HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP 240
           HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP
Sbjct: 181 HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP 240

Query: 241 RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF 300
           RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF
Sbjct: 241 RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF 300

Query: 301 DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA 360
           DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA
Sbjct: 301 DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA 360

Query: 361 LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR 420
           LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR
Sbjct: 361 LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR 420

Query: 421 HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN 480
           HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN
Sbjct: 421 HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN 480

Query: 481 GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS 540
           GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS
Sbjct: 481 GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS 540

Query: 541 LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG 600
           LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG
Sbjct: 541 LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG 600

Query: 601 AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL 660
           AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL
Sbjct: 601 AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL 660

Query: 661 MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ 720
           MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ
Sbjct: 661 MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ 720

Query: 721 ER 722
           ER
Sbjct: 721 ER 722


>gi|156415998 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 1519 bits (3934), Expect = 0.0
 Identities = 722/722 (100%), Positives = 722/722 (100%)

Query: 1   MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60
           MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP
Sbjct: 1   MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60

Query: 61  VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL 120
           VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL
Sbjct: 61  VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL 120

Query: 121 LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER 180
           LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER
Sbjct: 121 LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER 180

Query: 181 HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP 240
           HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP
Sbjct: 181 HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP 240

Query: 241 RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF 300
           RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF
Sbjct: 241 RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF 300

Query: 301 DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA 360
           DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA
Sbjct: 301 DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA 360

Query: 361 LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR 420
           LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR
Sbjct: 361 LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR 420

Query: 421 HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN 480
           HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN
Sbjct: 421 HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN 480

Query: 481 GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS 540
           GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS
Sbjct: 481 GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS 540

Query: 541 LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG 600
           LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG
Sbjct: 541 LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG 600

Query: 601 AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL 660
           AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL
Sbjct: 601 AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL 660

Query: 661 MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ 720
           MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ
Sbjct: 661 MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ 720

Query: 721 ER 722
           ER
Sbjct: 721 ER 722


>gi|156415996 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 1519 bits (3934), Expect = 0.0
 Identities = 722/722 (100%), Positives = 722/722 (100%)

Query: 1   MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60
           MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP
Sbjct: 1   MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCP 60

Query: 61  VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL 120
           VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL
Sbjct: 61  VCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLL 120

Query: 121 LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER 180
           LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER
Sbjct: 121 LELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERER 180

Query: 181 HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP 240
           HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP
Sbjct: 181 HLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP 240

Query: 241 RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF 300
           RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF
Sbjct: 241 RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF 300

Query: 301 DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA 360
           DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA
Sbjct: 301 DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPA 360

Query: 361 LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR 420
           LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR
Sbjct: 361 LLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARR 420

Query: 421 HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN 480
           HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN
Sbjct: 421 HRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEEN 480

Query: 481 GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS 540
           GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS
Sbjct: 481 GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS 540

Query: 541 LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG 600
           LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG
Sbjct: 541 LKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSG 600

Query: 601 AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL 660
           AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL
Sbjct: 601 AGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPEL 660

Query: 661 MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ 720
           MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ
Sbjct: 661 MALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQ 720

Query: 721 ER 722
           ER
Sbjct: 721 ER 722


>gi|7662092 zinc finger protein 536 [Homo sapiens]
          Length = 1300

 Score =  242 bits (618), Expect = 8e-64
 Identities = 228/779 (29%), Positives = 316/779 (40%), Gaps = 181/779 (23%)

Query: 19  AFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGE-RRFPCPVCGKRFRFNSILALHLR 77
           + +G +DLQ++ NG  +      M  +S  E  A + R++PCP+CGKRFRFNSIL+LH+R
Sbjct: 95  SLNGRVDLQQFLNGQNLGI----MSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMR 150

Query: 78  AHPGAQAFQCPHCGHRAAQRALLRSHLRTHQ-----PERPR-SPAARLLLELEERALLRE 131
            H G + F+CP+C HRAAQ+  L+ HLRTH+       R R     RLL ELEERA+LR+
Sbjct: 151 THTGEKPFKCPYCDHRAAQKGNLKIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRD 210

Query: 132 ARLGR--------------------ARSSGGMQATPATEGLARPQAPS------------ 159
            +L                      A  +  +QA  +   +A P  PS            
Sbjct: 211 KQLKGSLLQPRPDLKPPPHAQQAPLAACTLALQANHSVPDVAHP-VPSPKPASVQEDAVA 269

Query: 160 -SSAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERP 218
            ++ FRC +CKGKF+   E +RH+ ILH+P+KC LC F +SQEEEL+ H   AH   E  
Sbjct: 270 PAAGFRCTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQEEELISHVEKAHITAE-- 327

Query: 219 LAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQV 278
                                  S     P    E+ A                EFRC+V
Sbjct: 328 -----------------------SAQGQGPNGGGEQSAN---------------EFRCEV 349

Query: 279 CGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPAS 338
           CGQ F+Q+WFLKGHMRKHK SF+H C +CGR FKEPWFLKNHMKVH +KL          
Sbjct: 350 CGQVFSQAWFLKGHMRKHKDSFEHCCQICGRRFKEPWFLKNHMKVHLNKLSVKN-----K 404

Query: 339 GPARAPQPPDLGLLAYEP--------LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGR 390
            P+    P  +G ++ E         L         P  A   EP  L G   L   E  
Sbjct: 405 SPSDPEVPVPMGGMSQEAHANLYSRYLSCLQSGFMTPDKAGLSEPSQLYGKGELPMKEKE 464

Query: 391 PNGE----------GAEPGPGRSFGGFRPLSSALPARA-RRHRAEEPEEEEEVVEAEE-- 437
             G+          G   G   S  G   L   L +    R +A     E + V + +  
Sbjct: 465 ALGKLLSPISSMAHGVPEGDKHSLLGCLNLVPPLKSSCIERLQAAAKAAEMDPVNSYQAW 524

Query: 438 ETWARGRSL--GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGL------------- 482
           +  ARG ++  G L+  HP       H  + A A       + E  L             
Sbjct: 525 QLMARGMAMEHGFLSKEHPLQ---RNHEDTLANAGVLFDKEKREYVLVGADGSKQKMPAD 581

Query: 483 LVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRV------HTGERPYKCPHCDYAGT 536
           LV  T+    R    K  P        +H L   L        +  E+P +CP C     
Sbjct: 582 LVHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQTLEYNLQGPGNMKEKPTECPDCGRVFR 641

Query: 537 QSGSLKYHLQRHHR-------------EQRSGAG-------------PGPPPEPPPPSQR 570
               +  H + H R             ++R G+G             PG           
Sbjct: 642 TYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSSNVTEESGVG 701

Query: 571 GSAPQSGA--KPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGG------ 622
           G   Q+G+  + SP P++    +SS     +G   G ++      R+L +          
Sbjct: 702 GGLSQTGSAQEDSPHPSS---PSSSDIGEEAGRSAGVQQPALLRDRSLGSAMKDCPYCGK 758

Query: 623 ---EAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRP 678
               +  L + LR   G +       ++C  C +A      +  HL+ HH  R  G  P
Sbjct: 759 TFRTSHHLKVHLRIHTGEKP------YKCPHCDYAGTQSASLKYHLERHHRERQNGAGP 811



 Score =  134 bits (336), Expect = 4e-31
 Identities = 67/136 (49%), Positives = 86/136 (63%), Gaps = 10/136 (7%)

Query: 447 GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKS 506
           GS     P P      S+S  G +A  +A  ++  LL      +   G+  KDCP+CGK+
Sbjct: 708 GSAQEDSPHPSSP---SSSDIGEEAGRSAGVQQPALL-----RDRSLGSAMKDCPYCGKT 759

Query: 507 FRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGP--GPPPEP 564
           FR++HHLKVHLR+HTGE+PYKCPHCDYAGTQS SLKYHL+RHHRE+++GAGP  G PP  
Sbjct: 760 FRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQNGAGPLSGQPPNQ 819

Query: 565 PPPSQRGSAPQSGAKP 580
               +  S      +P
Sbjct: 820 DHKDEMSSKASLFIRP 835



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 11/79 (13%)

Query: 604  GSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGAL--------HRCLFCPFAT 655
            G   KP+    + R     + EPLDLS+R  P   + PG ++        H CLFC F T
Sbjct: 954  GGEEKPSGKS-SQRKSEKSQYEPLDLSVR--PDAASLPGSSVTVQDSIAWHGCLFCAFTT 1010

Query: 656  GAPELMALHLQVHHSRRAR 674
             + ELMALHLQ +H  +A+
Sbjct: 1011 SSMELMALHLQANHLGKAK 1029



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 45/193 (23%), Positives = 73/193 (37%), Gaps = 18/193 (9%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
           E+   CP CG+ FR    + +H R H   +  +         +R    S   +    R  
Sbjct: 628 EKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRST 687

Query: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATE---------------GLARPQAP 158
           +P +  + E E       ++ G A+      ++P++                 L R ++ 
Sbjct: 688 TPGSSNVTE-ESGVGGGLSQTGSAQEDSPHPSSPSSSDIGEEAGRSAGVQQPALLRDRSL 746

Query: 159 SSSAFRCPYCKGKFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPE 216
            S+   CPYC   FRTS   + HL  H   +P+KC  C +  +Q   L +H    H   +
Sbjct: 747 GSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHRERQ 806

Query: 217 RPLAATSAAPPPQ 229
                 S  PP Q
Sbjct: 807 NGAGPLSGQPPNQ 819



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 51/202 (25%), Positives = 70/202 (34%), Gaps = 34/202 (16%)

Query: 165 CPYCKGKFRTSAERERHLHILHRPWK-------CGLCS---FGSSQEEELLHHS------ 208
           CP C   FRT  +   H  +  R  K        GL      GS QE + +  S      
Sbjct: 633 CPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSGSDQESQSVSRSTTPGSS 692

Query: 209 -LTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE 267
            +T        L+ T +A    P P         S P      E    +     PA   +
Sbjct: 693 NVTEESGVGGGLSQTGSAQEDSPHP---------SSPSSSDIGEEAGRSAGVQQPALLRD 743

Query: 268 PPAPPEFR-CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS 326
                  + C  CG++F  S  LK H+R H     + CP C     +   LK H++ H  
Sbjct: 744 RSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSASLKYHLERHHR 803

Query: 327 KLGPLRAPGPASGPARAPQPPD 348
           +       GP SG     QPP+
Sbjct: 804 E--RQNGAGPLSG-----QPPN 818


>gi|7662010 zinc finger protein 516 [Homo sapiens]
          Length = 1163

 Score =  199 bits (506), Expect = 7e-51
 Identities = 167/623 (26%), Positives = 233/623 (37%), Gaps = 140/623 (22%)

Query: 59  CPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTH---------QP 109
           C +CGK F F S L+ H+R H G + ++CP+C HRA+Q+  L+ H+R+H         +P
Sbjct: 36  CCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEP 95

Query: 110 ERPRSP---------------------AARLLLELEERALLREARLGRARSSGGM----Q 144
           E   +P                     A   LL    +A       G +++  G      
Sbjct: 96  EAGEAPLGEMRASEGLDACASPTKSASACNRLLNGASQADGARVLNGASQADSGRVLLRS 155

Query: 145 ATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEEL 204
           +    EG A     + +A +C +CK +F    + E H+H  H+P+KC LCS+ + +EE L
Sbjct: 156 SKKGAEGSACAPGEAKAAVQCSFCKSQFERKKDLELHVHQAHKPFKCRLCSYATLREESL 215

Query: 205 LHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAA 264
           L H    H   + P +  +     +P+                                 
Sbjct: 216 LSHIERDHITAQGPGSGEACVENGKPE--------------------------------- 242

Query: 265 PEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVH 324
                +P EF C+VCGQ+F+Q+WFLK HM+KH+ SFDH C +CGR FKEPWFLKNHMK H
Sbjct: 243 ----LSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAH 298

Query: 325 ASKLGPLRAPGPASGPARA------PQPPDLGLLAYE-------------------PLGP 359
             K G    P     P          +    GL  YE                    +  
Sbjct: 299 GPKTGSKNRPKSELDPIATINNVVQEEVIVAGLSLYEVCAKCGNLFTNLDSLNAHNAIHR 358

Query: 360 ALLLAPAPTPAER-REPPSLLGYLSLRAGEGRPNGEGAE-PG--PGRSFGGFRPLSSALP 415
            +  +    PAE   E PS      L+    RP+  G   PG   GR      P++S   
Sbjct: 359 RVEASRTRAPAEEGAEGPSDTKQFFLQCLNLRPSAAGDSCPGTQAGRRVAELDPVNSYQA 418

Query: 416 AR-ARRHRAEEPEE--------------------EEEVVEAEEETWARGRSLGSLASLHP 454
            + A R +  EP E                      E V   +E   R +   +      
Sbjct: 419 WQLATRGKVAEPAEYLKYGAWDEALAGDVAFDKDRREYVLVSQEKRKREQDAPAAQGPPR 478

Query: 455 RPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLK 514
           +   GPG  A A     RS A          G            +C  CGK FR+ H + 
Sbjct: 479 KRASGPGDPAPAGHLDPRSAARPNRRAAATTGQ-------GKSSECFECGKIFRTYHQMV 531

Query: 515 VHLRVHTGERPYKCPHCDYAG-TQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSA 573
           +H RVH   R  +    D A   + GSL             G     P  P        +
Sbjct: 532 LHSRVHRRARRERDSDGDRAARARCGSLS-----------EGDSASQPSSPGSACAAADS 580

Query: 574 PQSGAKPSPQPATWVEGASSPRP 596
           P SG        +  EGA  P P
Sbjct: 581 PGSGLADEAAEDSGEEGAPEPAP 603



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 54/185 (29%), Positives = 80/185 (43%), Gaps = 22/185 (11%)

Query: 492 GRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHRE 551
           G  AT   C  CGKSF     L  H+R HTGE+PYKCP+CD+  +Q G+LK H++ H   
Sbjct: 28  GDKATCHTCCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRSH--- 84

Query: 552 QRSGAGPGPPPEPPPPSQRGSAPQSGAKP--SPQPATWVEGASSPRPPSSGAGPGSRRKP 609
            R+G              +G  P++G  P    + +  ++  +SP   +S          
Sbjct: 85  -RTGT-----------LIQGHEPEAGEAPLGEMRASEGLDACASPTKSASACNRLLNGAS 132

Query: 610 ASPGRTLRNG--RGGEAEPLDLSLRAGPGGEA---GPGGALHRCLFCPFATGAPELMALH 664
            + G  + NG  +      L  S + G  G A   G   A  +C FC       + + LH
Sbjct: 133 QADGARVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAVQCSFCKSQFERKKDLELH 192

Query: 665 LQVHH 669
           +   H
Sbjct: 193 VHQAH 197



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 158/779 (20%), Positives = 244/779 (31%), Gaps = 196/779 (25%)

Query: 57  FPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPE-----R 111
           FPC VCG+ F     L  H++ H G+    C  CG R  +   L++H++ H P+     R
Sbjct: 248 FPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKEPWFLKNHMKAHGPKTGSKNR 307

Query: 112 PRS---PAARLLLELEERALLRE-------ARLG---------------RARSSGGMQAT 146
           P+S   P A +   ++E  ++         A+ G                 R        
Sbjct: 308 PKSELDPIATINNVVQEEVIVAGLSLYEVCAKCGNLFTNLDSLNAHNAIHRRVEASRTRA 367

Query: 147 PATEGLARPQ------------APSSSAFRCP----------------------YCKGKF 172
           PA EG   P              PS++   CP                        +GK 
Sbjct: 368 PAEEGAEGPSDTKQFFLQCLNLRPSAAGDSCPGTQAGRRVAELDPVNSYQAWQLATRGKV 427

Query: 173 RTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQP 232
              AE     ++ +  W   L     + +++   + L +    +R   A +A  PP+ + 
Sbjct: 428 AEPAE-----YLKYGAWDEALAG-DVAFDKDRREYVLVSQEKRKREQDAPAAQGPPRKRA 481

Query: 233 QPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGH 292
             P  P P     P     P R A  T       E                         
Sbjct: 482 SGPGDPAPAGHLDPRSAARPNRRAAATTGQGKSSE------------------------- 516

Query: 293 MRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLL 352
                      C  CG+ F+    +  H +VH        + G  +  AR     + G  
Sbjct: 517 -----------CFECGKIFRTYHQMVLHSRVHRRARRERDSDGDRAARARCGSLSE-GDS 564

Query: 353 AYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPG----RSFGGFR 408
           A +P  P    A A +P            L+  A E        EP PG    R      
Sbjct: 565 ASQPSSPGSACAAADSPGSG---------LADEAAEDSGEEGAPEPAPGGQPRRCCFSEE 615

Query: 409 PLSSALPARARRHRAEEPEEEEEVVEAEE---------ETWARGRSLG----------SL 449
             S+ L +  + H+  +   E +  E++          E  +R  S             +
Sbjct: 616 VTSTELSSGDQSHKMGDNASERDTGESKAGIAASVSILENSSRETSRRQEQHRFSMDLKM 675

Query: 450 ASLHPR-----PGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCG 504
            + HP+     PG+G     S+ GA+ ++    E+   L       GG+ A   D     
Sbjct: 676 PAFHPKQEVPVPGDGV-EFPSSTGAEGQTGHPAEKLSDLHNKEHSGGGKRALAPDLMPLD 734

Query: 505 KSFRS----------AHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554
            S RS          A  L+  L VH       CP+C +       L  H +  HR   +
Sbjct: 735 LSARSTRDDPSNKETASSLQAALVVH------PCPYCSHKTYYPEVLWMHKRIWHRVSCN 788

Query: 555 GAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGR 614
              P P  +P           +G K       ++  +    PP   A  G   +P    R
Sbjct: 789 SVAP-PWIQP-----------NGYKSIRSNLVFLSRSGRTGPPP--ALGGKECQPLLLAR 834

Query: 615 TLRN-------GRGGEAEPLDLSLRAG---PGGEAGPGGALHRCLFCPFATGAPELMALH 664
             R        G    + PL +  +A       E+  GG     L+ P   G  +    H
Sbjct: 835 FTRTQVPGGMPGSKSGSSPLGVVTKAASMPKNKESHSGGPC--ALWAPGPDGYRQTKPCH 892

Query: 665 LQVHHSRRARG-RRPPQADASPPYARVPSG--------ETPPSPSQEGEEGSGLSRPGE 714
            Q  H    +G    P+ +AS      P G         TP   ++ G + S  S+P E
Sbjct: 893 GQEPHGAATQGPLAKPRQEASSKPVPAPGGGGFSRSATPTPTVIARAGAQPSANSKPVE 951



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 80/337 (23%), Positives = 117/337 (34%), Gaps = 47/337 (13%)

Query: 247 EPEPEPEREATPTPAPAAPE-EPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACP 305
           E E E  R  +PT A    E +        C +CG+SF     L  HMRKH     + CP
Sbjct: 6   EAEMELRRGPSPTRAGRGHEVDGDKATCHTCCICGKSFPFQSSLSQHMRKHTGEKPYKCP 65

Query: 306 VCGRCFKEPWFLKNHMKVHASKLGPL-RAPGPASGPA-----RAPQPPDLGLLAYEPLGP 359
            C     +   LK H++ H  + G L +   P +G A     RA +  D       P   
Sbjct: 66  YCDHRASQKGNLKIHIRSH--RTGTLIQGHEPEAGEAPLGEMRASEGLD---ACASPTKS 120

Query: 360 ALLLAPAPTPAERREPPSLL--------GYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLS 411
           A         A + +   +L        G + LR+ +    G    PG  ++        
Sbjct: 121 ASACNRLLNGASQADGARVLNGASQADSGRVLLRSSKKGAEGSACAPGEAKAAVQCSFCK 180

Query: 412 SALPAR----ARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAA 467
           S    +       H+A +P +      A      R  SL S         +GPG   +  
Sbjct: 181 SQFERKKDLELHVHQAHKPFKCRLCSYAT----LREESLLSHIERDHITAQGPGSGEACV 236

Query: 468 GAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYK 527
                      ENG      +PE   G     C  CG++F     LK H++ H G   + 
Sbjct: 237 -----------ENG------KPELSPGEF--PCEVCGQAFSQTWFLKAHMKKHRGSFDHG 277

Query: 528 CPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEP 564
           C  C     +   LK H++ H  +  S   P    +P
Sbjct: 278 CHICGRRFKEPWFLKNHMKAHGPKTGSKNRPKSELDP 314



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 16/35 (45%), Positives = 19/35 (54%)

Query: 271  PPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACP 305
            P EF C  CG+SF Q   L+ HMR H   F+   P
Sbjct: 1095 PGEFVCIECGKSFHQPGHLRAHMRAHSVVFESDGP 1129



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 39/158 (24%), Positives = 57/158 (36%), Gaps = 48/158 (30%)

Query: 212  HGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPER----------------- 254
            H AP+   A  SA    QPQ  PP + E  + P P  EP  +                  
Sbjct: 968  HSAPDSLKAKFSA----QPQGPPPAKGEGGAPPLPPREPPSKAAQELRTLATCAAGSRGD 1023

Query: 255  ---EATPTPAPAAP------EEPPAPP-EFRCQVCG----------QSFTQSWFLKGHMR 294
               +A P  A A P      +EP A   E R  +             +  Q W + G   
Sbjct: 1024 AALQAQPGVAGAPPVLHSIKQEPVAEGHEKRLDILNIFKTYIPKDFATLYQGWGVSGPGL 1083

Query: 295  KHKASF-------DHACPVCGRCFKEPWFLKNHMKVHA 325
            +H+ +        +  C  CG+ F +P  L+ HM+ H+
Sbjct: 1084 EHRGTLRTQARPGEFVCIECGKSFHQPGHLRAHMRAHS 1121



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 40/121 (33%), Positives = 48/121 (39%), Gaps = 25/121 (20%)

Query: 553  RSGAGPGPPPEP------PP------PSQRGSAPQS-----GAKPSPQPATWVEGASSPR 595
            R+GA P    +P      PP      P+ + SAP S      A+P   P    EG + P 
Sbjct: 938  RAGAQPSANSKPVEKFGVPPAGAGFAPTNKHSAPDSLKAKFSAQPQGPPPAKGEGGAPPL 997

Query: 596  PPSSGAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFAT 655
            PP     P S  K A   RTL     G     D +L+A P G AG    LH     P A 
Sbjct: 998  PPRE---PPS--KAAQELRTLATCAAGSRG--DAALQAQP-GVAGAPPVLHSIKQEPVAE 1049

Query: 656  G 656
            G
Sbjct: 1050 G 1050



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 11/22 (50%), Positives = 14/22 (63%)

Query: 500  CPFCGKSFRSAHHLKVHLRVHT 521
            C  CGKSF    HL+ H+R H+
Sbjct: 1100 CIECGKSFHQPGHLRAHMRAHS 1121


>gi|148276998 zinc finger protein 628 [Homo sapiens]
          Length = 1055

 Score =  157 bits (396), Expect = 4e-38
 Identities = 183/661 (27%), Positives = 228/661 (34%), Gaps = 157/661 (23%)

Query: 34  AVSAGSLGMGAVSWSE-------SRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQ 86
           A   G  G+ A  WS           GER +PCP C K F+ +S L  H   H G + + 
Sbjct: 115 AFICGQCGL-AFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERPYT 173

Query: 87  CPHCGHRAAQRALLRSHLRTHQPERP-RSPAARLLLELEERALLREARLGRARSSGGMQA 145
           C  CG    Q   LR H R H  ERP R P            LL +   G A + G   A
Sbjct: 174 CGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGTASA 233

Query: 146 TPATEGL-------------------ARPQAPSSSAFRCPYCKGKFRTSAERERHLHILH 186
            P  +                     + P  P+      P     F  +AE    L    
Sbjct: 234 APPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAPPPPPPPVVPELFLAAAETTVEL---- 289

Query: 187 RPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQP 246
             ++C  C  G S EE LL H         +P     AAP  QPQ  P   P+    P P
Sbjct: 290 -VYRCDGCEQGFSSEELLLEH---------QPCPGPDAAP--QPQEAPAEAPKADQPPSP 337

Query: 247 EPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHA--C 304
            P+P P     P  APA        P F C  CG+SF     L  H   H A+   A  C
Sbjct: 338 LPQPPP-----PAAAPA--------PGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRC 384

Query: 305 PVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPA-SGPARAPQPPDLGLLAYEPLGPALLL 363
             C   F +   L  H + H  +    R P  A +     PQ         EPL PA   
Sbjct: 385 GSCDGSFPQLASLLAHQQCHVEEAAAGRPPPQAEAAEVTCPQ---------EPLAPA--- 432

Query: 364 APAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRA 423
           AP P P     PPS        A   RP  + AE G  +SF G    SS L    R H  
Sbjct: 433 APVPPP-----PPSA------PASAERPY-KCAECG--KSFKG----SSGLRYHLRDHTG 474

Query: 424 EEPEEEEE-----------VVEAEEETWARGRSLGSLA-----------SLHPRPGEGPG 461
           E P +  E            +     T  R  + G               L    GE P 
Sbjct: 475 ERPYQCGECGKAFKRSSLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLHSGERP- 533

Query: 462 HSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHT 521
           ++    G   R+T+    +  +  G RP          C  CGKSF    +L+ H RVHT
Sbjct: 534 YACGECGKAFRNTSCLRRHRHVHTGERPHA--------CGVCGKSFAQTSNLRQHQRVHT 585

Query: 522 GERPYKCPHCDYAGTQSGSLKYH------------------------LQRHHREQR---- 553
           GERP++CP C    T S +L  H                        LQRH R       
Sbjct: 586 GERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPICGRGFVMAAYLQRHLRTHAPANT 645

Query: 554 --SGAGPGPPPEPPPPSQRGSAPQSGAKPSPQP------ATWVEGASSPRPPSSGAGPGS 605
             S   P   P+PP P     AP +       P      +  V G ++  P    A P S
Sbjct: 646 PPSTTAPAAGPQPPAPLAAARAPPATQDVHVLPHLQATLSLEVAGGTAQAPSLGPAAPNS 705

Query: 606 R 606
           +
Sbjct: 706 Q 706



 Score =  108 bits (271), Expect = 1e-23
 Identities = 161/649 (24%), Positives = 218/649 (33%), Gaps = 175/649 (26%)

Query: 41  GMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALL 100
           G G      + A   ++ C  CGK FR++S L  H R H G + ++CP C       + L
Sbjct: 16  GAGEKPGPAAPAPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSAL 75

Query: 101 RSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSS 160
             H R H  ERP                                                
Sbjct: 76  LYHQRGHTGERP------------------------------------------------ 87

Query: 161 SAFRCPYCKGKFRTSA--ERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERP 218
             ++CP C   F+ S+  +  R +H   R + CG C           +H L  H      
Sbjct: 88  --YQCPDCPKAFKRSSLLQIHRSVHTGLRAFICGQCGLAFKWSSHYQYH-LRQH------ 138

Query: 219 LAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQV 278
              T   P P P   P       S+ +       ER  T                  C V
Sbjct: 139 ---TGERPYPCPDC-PKAFKNSSSLRRHRHVHTGERPYT------------------CGV 176

Query: 279 CGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPAS 338
           CG+SFTQS  L+ H R H       CP+C + F     L  H + H    G   APG AS
Sbjct: 177 CGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTH----GAAPAPGTAS 232

Query: 339 GPARAPQPPDLGLL----AY-----EPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEG 389
             A  PQ  + G +    AY     +P  P     PAP PA    PP ++  L L A E 
Sbjct: 233 A-APPPQSREPGKVFVCDAYLQRHLQPHSP-----PAP-PAPPPPPPPVVPELFLAAAE- 284

Query: 390 RPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSL 449
                                 + +    R    E+    EE++   +       +    
Sbjct: 285 ----------------------TTVELVYRCDGCEQGFSSEELLLEHQPCPGPDAA---- 318

Query: 450 ASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRS 509
               P+P E P  +  A   Q  S   Q           P     A G  C  CGKSFR+
Sbjct: 319 ----PQPQEAPAEAPKAD--QPPSPLPQPP---------PPAAAPAPGFACLPCGKSFRT 363

Query: 510 AHHLKVHLRVH--TGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPP 567
              L  H   H   G + ++C  CD +  Q  SL  H Q H  E  +G        PPP 
Sbjct: 364 VAGLSRHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQCHVEEAAAG-------RPPPQ 416

Query: 568 SQRG--SAPQSGAKPS-PQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEA 624
           ++    + PQ    P+ P P         P PPS+ A      K A  G++ +   G   
Sbjct: 417 AEAAEVTCPQEPLAPAAPVP---------PPPPSAPASAERPYKCAECGKSFKGSSG--- 464

Query: 625 EPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRA 673
             L   LR   G         ++C  C  A     L+A+H +VH   RA
Sbjct: 465 --LRYHLRDHTGERP------YQCGECGKAFKRSSLLAIHQRVHTGLRA 505



 Score = 86.7 bits (213), Expect = 7e-17
 Identities = 77/281 (27%), Positives = 107/281 (38%), Gaps = 26/281 (9%)

Query: 6   PRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCPVCGKR 65
           P AP+  + P PP+     + + Y       +     G         GER + C  CGK 
Sbjct: 428 PLAPAAPVPPPPPSAPASAE-RPYKCAECGKSFKGSSGLRYHLRDHTGERPYQCGECGKA 486

Query: 66  FRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRS--PAARLLLEL 123
           F+ +S+LA+H R H G +AF C  CG      +  + HLR H  ERP +     +     
Sbjct: 487 FKRSSLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLHSGERPYACGECGKAFRNT 546

Query: 124 EERALLREARLGRARSSGGM--QATPATEGLARPQA--PSSSAFRCPYCKGKFRTSAERE 179
                 R    G    + G+  ++   T  L + Q        FRCP C   F  S+   
Sbjct: 547 SCLRRHRHVHTGERPHACGVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLL 606

Query: 180 RH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQ 237
            H   H   RP+ C +C  G      L  H L  H     P + T+ A  PQP   P P 
Sbjct: 607 LHQRTHSAERPFTCPICGRGFVMAAYLQRH-LRTHAPANTPPSTTAPAAGPQP---PAPL 662

Query: 238 PEPRSVPQPEP-EPEPEREAT------------PTPAPAAP 265
              R+ P  +     P  +AT            P+  PAAP
Sbjct: 663 AAARAPPATQDVHVLPHLQATLSLEVAGGTAQAPSLGPAAP 703



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 74/275 (26%), Positives = 94/275 (34%), Gaps = 84/275 (30%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYH--------------- 544
           C  CGKSF  + +L+ H RVHTGERP++CP C    T S +L  H               
Sbjct: 174 CGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGTASA 233

Query: 545 ------------------LQRHHREQRSGAGPGPPPEPPPP------------------- 567
                             LQRH +     A P PPP PPP                    
Sbjct: 234 APPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAPPPPPPPVVPELFLAAAETTVELVYRC 293

Query: 568 --SQRG-----------------SAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRK 608
              ++G                 +APQ    P+  P      +  P+PP   A P     
Sbjct: 294 DGCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFA 353

Query: 609 PASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVH 668
               G++ R   G       LS      G AG  G   RC  C  +      +  H Q H
Sbjct: 354 CLPCGKSFRTVAG-------LSRHQHSHGAAG--GQAFRCGSCDGSFPQLASLLAHQQCH 404

Query: 669 HSRRARGRRPPQADAS----PPYARVPSGETPPSP 699
               A GR PPQA+A+    P     P+   PP P
Sbjct: 405 VEEAAAGRPPPQAEAAEVTCPQEPLAPAAPVPPPP 439



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 54/188 (28%), Positives = 67/188 (35%), Gaps = 11/188 (5%)

Query: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP 112
           GER   C VCGK F   S L  H R H G + F+CP C       + L  H RTH  ERP
Sbjct: 558 GERPHACGVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERP 617

Query: 113 RSPAARLLLELEERALLREARLGRARSSGGMQATP--ATEGLARPQAPSS-SAFRCPYCK 169
                     +  R  +  A L R   +     TP   T   A PQ P+  +A R P   
Sbjct: 618 ------FTCPICGRGFVMAAYLQRHLRTHAPANTPPSTTAPAAGPQPPAPLAAARAPPAT 671

Query: 170 GKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQ 229
                    +  L +          S G +         L    A    L  +S  PP  
Sbjct: 672 QDVHVLPHLQATLSLEVAGGTAQAPSLGPAAPNSQTF--LLVQTAQGLQLIPSSVQPPTP 729

Query: 230 PQPQPPPQ 237
           P P  PP+
Sbjct: 730 PPPPAPPK 737



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 65/246 (26%), Positives = 91/246 (36%), Gaps = 18/246 (7%)

Query: 450 ASLHPRPGEGPGHSASAAGAQARSTATQEE---NGLLVGGTRPEGGRGATGKDCPFCGKS 506
           AS     GE PG +A A  AQ       +    +  L+   R   G       CP C K+
Sbjct: 11  ASTAEGAGEKPGPAAPAPAAQYECGECGKSFRWSSRLLHHQRTHTGERPY--KCPDCPKA 68

Query: 507 FRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGP-GPPPEPP 565
           F+ +  L  H R HTGERPY+CP C  A  +S  L+ H   H   +    G  G   +  
Sbjct: 69  FKGSSALLYHQRGHTGERPYQCPDCPKAFKRSSLLQIHRSVHTGLRAFICGQCGLAFKWS 128

Query: 566 PPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAE 625
              Q      +G +P P P         P+   + +     R   +  R    G  G++ 
Sbjct: 129 SHYQYHLRQHTGERPYPCP-------DCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSF 181

Query: 626 PLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRPPQADASP 685
               +LR         G    RC  CP        + LH + H +  A G     + A P
Sbjct: 182 TQSTNLRQHQ--RVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPG---TASAAPP 236

Query: 686 PYARVP 691
           P +R P
Sbjct: 237 PQSREP 242


>gi|22749325 zinc finger protein 48 [Homo sapiens]
          Length = 618

 Score =  137 bits (344), Expect = 5e-32
 Identities = 146/554 (26%), Positives = 197/554 (35%), Gaps = 128/554 (23%)

Query: 42  MGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLR 101
           +G   W ++ + +R   C  CGK FR  S L  H R H G + ++C  CG      +   
Sbjct: 98  LGEPRWGQA-SSDRAAVCGECGKSFRQMSDLVKHQRTHTGEKPYKCGVCGKGFGDSSARI 156

Query: 102 SHLRTHQPERP---RSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAP 158
            H RTH  E+P   R PA                ++ R+R   G + T            
Sbjct: 157 KHQRTHSGEKPYRARPPAQG------------PPKIPRSRIPAGERPTI----------- 193

Query: 159 SSSAFRCPYCKGKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPE 216
                 C  C   FR S++  +H   H   +P+KCG+C  G       + H  T  G   
Sbjct: 194 ------CGECGKSFRLSSDLVKHQRTHTGEKPYKCGICGKGFGDSSARIKHQRTHRG--- 244

Query: 217 RPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATP-TPAPAAPEEPPAPPEFR 275
                           + PP+P         P  +P R AT  T  P A ++P     + 
Sbjct: 245 ----------------EQPPRPVV-------PRRQPSRAATAATQGPKAQDKP-----YI 276

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPG 335
           C  CG+ F  S  L  H R H       C VCG+ F     L  H++VH  +  P   P 
Sbjct: 277 CTDCGKRFVLSCSLLSHQRSHLGPKPFGCDVCGKEFARGSDLVKHLRVHTGEK-PYLCPE 335

Query: 336 PASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEG 395
              G A                                +  + + +L   +GE RP+   
Sbjct: 336 CGKGFA--------------------------------DSSARVKHLRTHSGE-RPH--- 359

Query: 396 AEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPR 455
           A P   R+F     LSS L     RHR    E ++            G  L +L    P 
Sbjct: 360 ACPECDRTFS----LSSTL----LRHRLTHMEPQDFSFP--------GYPLPALIPSPPP 403

Query: 456 PGEGPG-----HSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSA 510
           P  G        S S +G        + E G    G  P    G     CP CGK FR +
Sbjct: 404 PPLGTSPPLTPRSPSHSGEPFGLPGLEPEPGGPQAGEPPPPLAGDKPHKCPECGKGFRRS 463

Query: 511 HHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGP---PPEPPPP 567
             L  H RVHTGE+PY CP C      S +   HL+ H  E+     P     P  PP P
Sbjct: 464 SDLVKHHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRGERARPPPPSTLLRPHNPPGP 523

Query: 568 SQRGSAPQSGAKPS 581
                 P+  A+PS
Sbjct: 524 VPMAPRPRVRAQPS 537



 Score =  114 bits (286), Expect = 2e-25
 Identities = 107/391 (27%), Positives = 141/391 (36%), Gaps = 104/391 (26%)

Query: 51  RAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPE 110
           +A ++ + C  CGKRF  +  L  H R+H G + F C  CG   A+ + L  HLR H  E
Sbjct: 269 KAQDKPYICTDCGKRFVLSCSLLSHQRSHLGPKPFGCDVCGKEFARGSDLVKHLRVHTGE 328

Query: 111 RPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKG 170
           +P                                                  + CP C  
Sbjct: 329 KP--------------------------------------------------YLCPECGK 338

Query: 171 KFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLT-----AHGAPERPLAATS 223
            F  S+ R +HL  H   RP  C  C    S    LL H LT         P  PL A  
Sbjct: 339 GFADSSARVKHLRTHSGERPHACPECDRTFSLSSTLLRHRLTHMEPQDFSFPGYPLPALI 398

Query: 224 AAPPPQPQPQPPP--------QPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFR 275
            +PPP P    PP          EP  +P  EPEP   +   P P P A ++P      +
Sbjct: 399 PSPPPPPLGTSPPLTPRSPSHSGEPFGLPGLEPEPGGPQAGEP-PPPLAGDKP-----HK 452

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPG 335
           C  CG+ F +S  L  H R H     + CP CG+ F +      H++ H           
Sbjct: 453 CPECGKGFRRSSDLVKHHRVHTGEKPYLCPECGKGFADSSARVKHLRTH----------- 501

Query: 336 PASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEG 395
              G    P PP   L  + P GP  +   AP P  R +P          +G  +P+  G
Sbjct: 502 --RGERARPPPPSTLLRPHNPPGPVPM---APRPRVRAQP----------SGPSQPHVCG 546

Query: 396 AEPGPGRSFGGFRPLSSALPARARRHRAEEP 426
                G+ F    P SS L    R H  E+P
Sbjct: 547 F---CGKEF----PRSSDLVKHRRTHTGEKP 570



 Score =  101 bits (252), Expect = 2e-21
 Identities = 87/332 (26%), Positives = 115/332 (34%), Gaps = 71/332 (21%)

Query: 40  LGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRAL 99
           L    +S   S  G + F C VCGK F   S L  HLR H G + + CP CG   A  + 
Sbjct: 286 LSCSLLSHQRSHLGPKPFGCDVCGKEFARGSDLVKHLRVHTGEKPYLCPECGKGFADSSA 345

Query: 100 LRSHLRTHQPERPRS-PAARLLLELEERALLRE--------------------------- 131
              HLRTH  ERP + P       L    LLR                            
Sbjct: 346 RVKHLRTHSGERPHACPECDRTFSLSS-TLLRHRLTHMEPQDFSFPGYPLPALIPSPPPP 404

Query: 132 -------------ARLGRARSSGGMQATPATEGLARPQAP--SSSAFRCPYCKGKFRTSA 176
                        +  G      G++  P       P  P       +CP C   FR S+
Sbjct: 405 PLGTSPPLTPRSPSHSGEPFGLPGLEPEPGGPQAGEPPPPLAGDKPHKCPECGKGFRRSS 464

Query: 177 ERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQP--QP 232
           +  +H  +H   +P+ C  C  G +     + H  T  G   RP       PPP    +P
Sbjct: 465 DLVKHHRVHTGEKPYLCPECGKGFADSSARVKHLRTHRGERARP-------PPPSTLLRP 517

Query: 233 QPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGH 292
             PP P P +       P P   A     P+ P +P       C  CG+ F +S  L  H
Sbjct: 518 HNPPGPVPMA-------PRPRVRA----QPSGPSQPHV-----CGFCGKEFPRSSDLVKH 561

Query: 293 MRKHKASFDHACPVCGRCFKEPWFLKNHMKVH 324
            R H     + C  CG+ F +      H + H
Sbjct: 562 RRTHTGEKPYKCAECGKGFGDSSARIKHQRGH 593



 Score = 96.3 bits (238), Expect = 9e-20
 Identities = 124/481 (25%), Positives = 173/481 (35%), Gaps = 78/481 (16%)

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPG 335
           C  CG+SF Q   L  H R H     + C VCG+ F +      H + H+ +  P RA  
Sbjct: 114 CGECGKSFRQMSDLVKHQRTHTGEKPYKCGVCGKGFGDSSARIKHQRTHSGEK-PYRARP 172

Query: 336 PASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEG 395
           PA GP + P+       +  P G    +         R    L+ +     GE +P   G
Sbjct: 173 PAQGPPKIPR-------SRIPAGERPTIC-GECGKSFRLSSDLVKHQRTHTGE-KPYKCG 223

Query: 396 AEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPR 455
                G+ FG     SSA     R HR E+P     VV   + + A      + A+  P+
Sbjct: 224 I---CGKGFGD----SSARIKHQRTHRGEQPPRP--VVPRRQPSRA-----ATAATQGPK 269

Query: 456 PGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKV 515
             + P +  +  G +   + +   +     G +P G        C  CGK F     L  
Sbjct: 270 AQDKP-YICTDCGKRFVLSCSLLSHQRSHLGPKPFG--------CDVCGKEFARGSDLVK 320

Query: 516 HLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH--------------------------- 548
           HLRVHTGE+PY CP C      S +   HL+ H                           
Sbjct: 321 HLRVHTGEKPYLCPECGKGFADSSARVKHLRTHSGERPHACPECDRTFSLSSTLLRHRLT 380

Query: 549 HREQRSGAGPGPP-----PEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAG- 602
           H E +  + PG P     P PPPP    S P +   PS     +      P P    AG 
Sbjct: 381 HMEPQDFSFPGYPLPALIPSPPPPPLGTSPPLTPRSPSHSGEPFGLPGLEPEPGGPQAGE 440

Query: 603 PGSRRKPASPGRTLRNGRG-GEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELM 661
           P        P +    G+G   +  L    R   G +       + C  C          
Sbjct: 441 PPPPLAGDKPHKCPECGKGFRRSSDLVKHHRVHTGEKP------YLCPECGKGFADSSAR 494

Query: 662 ALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSP-SQEGEEGSGLSRPGEAGLGGQ 720
             HL+ H   RA  R PP +    P+   P G  P +P  +   + SG S+P   G  G+
Sbjct: 495 VKHLRTHRGERA--RPPPPSTLLRPHN--PPGPVPMAPRPRVRAQPSGPSQPHVCGFCGK 550

Query: 721 E 721
           E
Sbjct: 551 E 551



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 32/127 (25%), Positives = 42/127 (33%), Gaps = 31/127 (24%)

Query: 587 WVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGP----- 641
           WV+     +P     GP          R L   R G+A     S RA   GE G      
Sbjct: 79  WVQREGLGKPQPRDRGP----------RLLGEPRWGQAS----SDRAAVCGECGKSFRQM 124

Query: 642 -----------GGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRPP-QADASPPYAR 689
                      G   ++C  C    G       H + H   +    RPP Q     P +R
Sbjct: 125 SDLVKHQRTHTGEKPYKCGVCGKGFGDSSARIKHQRTHSGEKPYRARPPAQGPPKIPRSR 184

Query: 690 VPSGETP 696
           +P+GE P
Sbjct: 185 IPAGERP 191


>gi|116256460 zinc finger protein 775 [Homo sapiens]
          Length = 537

 Score =  129 bits (323), Expect = 1e-29
 Identities = 151/570 (26%), Positives = 201/570 (35%), Gaps = 104/570 (18%)

Query: 5   RPRAPSGHLAPSPPAF--DGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCPVC 62
           RPRA  G      P +    E D       P  ++G L     S      GE  F C  C
Sbjct: 59  RPRALGGQEESGSPRWAPPTEQDAGLAGRAPGSASGPLSPSLSS------GEGHFVCLDC 112

Query: 63  GKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLE 122
           GKRF + S L +H R H G + + C  CG   +Q+  L  H R H  ERP          
Sbjct: 113 GKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRF 172

Query: 123 LEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERERHL 182
            +++ LL+  +           + PAT               CP C+  FR       H 
Sbjct: 173 SQKQHLLKHQKT---------HSRPATHS-------------CPECERCFRHQVGLRIHQ 210

Query: 183 HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPP------- 235
               R            Q      H L    A  R  A      PP+ +P+         
Sbjct: 211 RAHAR----------DRQGSRAGLHELIQDAAARR--ACRLQPGPPRGRPEWAWLGLCQG 258

Query: 236 --PQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHM 293
              QP  R+                  A + PE P  P +F C  CG+SFT    L  H 
Sbjct: 259 WWGQPGARA------------------AVSGPEGPGEPRQFICNECGKSFTWWSSLNIHQ 300

Query: 294 RKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLA 353
           R H     +ACP CGR F +   L  H++ H  +      P P     R  +     L  
Sbjct: 301 RIHTGERPYACPECGRRFSQKPNLTRHLRNHTGE-----RPHPCPHCGRGFRQKQHLLKH 355

Query: 354 YEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSA 413
                P    AP P+  +     S     +LRA + R +   AEP       G +P + A
Sbjct: 356 LRTHLPGAQAAPCPSCGK-----SCRSRAALRAHQ-RAHAV-AEPAVPAGEPGDQPQAEA 408

Query: 414 LPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARS 473
           +P  A R     P   +    A +  W RG++   LA     PGE      +  G     
Sbjct: 409 IPGLAAR-----PRSSQRSPGARDTLWGRGQA--GLAG----PGEPRQFICNECGKSFSW 457

Query: 474 TATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDY 533
            +    +  +  G RP          CP CG+ F    +L  H R HTGERPY CP C  
Sbjct: 458 WSALTIHQRIHTGERP--------YPCPECGRRFSQKPNLTRHRRNHTGERPYLCPACGR 509

Query: 534 AGTQSGSLKYHLQRHHREQRSGAGPGPPPE 563
             +Q    K HL +H R  R+     P  E
Sbjct: 510 GFSQ----KQHLLKHQRVHRAAPACSPKEE 535



 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 105/425 (24%), Positives = 148/425 (34%), Gaps = 107/425 (25%)

Query: 1   MEGSRPRAPSGHLAPSPPAFDGE---LDL-QRYSNGPAVSAGSLGMGAVSWSESRAGERR 56
           + G  P + SG L+PS  + +G    LD  +R+S   ++              +  GE+ 
Sbjct: 84  LAGRAPGSASGPLSPSLSSGEGHFVCLDCGKRFSWWSSLKIHQ---------RTHTGEKP 134

Query: 57  FPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQ-------P 109
           + C  CGK F     LA H R H G + F CP C  R +Q+  L  H +TH        P
Sbjct: 135 YLCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQHLLKHQKTHSRPATHSCP 194

Query: 110 ERPRSPAARLLLELEERALLREARLGR-----------ARSSGGMQATP----------- 147
           E  R    ++ L + +RA  R+ +  R           AR +  +Q  P           
Sbjct: 195 ECERCFRHQVGLRIHQRAHARDRQGSRAGLHELIQDAAARRACRLQPGPPRGRPEWAWLG 254

Query: 148 ----------ATEGLARPQAPSS-SAFRC------------------------PY----C 168
                     A   ++ P+ P     F C                        PY    C
Sbjct: 255 LCQGWWGQPGARAAVSGPEGPGEPRQFICNECGKSFTWWSSLNIHQRIHTGERPYACPEC 314

Query: 169 KGKFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLT----AHGAP------- 215
             +F       RHL  H   RP  C  C  G  Q++ LL H  T    A  AP       
Sbjct: 315 GRRFSQKPNLTRHLRNHTGERPHPCPHCGRGFRQKQHLLKHLRTHLPGAQAAPCPSCGKS 374

Query: 216 -------ERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPE------REATPTPAP 262
                       A + A P  P  +P  QP+  ++P     P         R+       
Sbjct: 375 CRSRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAARPRSSQRSPGARDTLWGRGQ 434

Query: 263 AAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMK 322
           A    P  P +F C  CG+SF+    L  H R H     + CP CGR F +   L  H +
Sbjct: 435 AGLAGPGEPRQFICNECGKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNLTRHRR 494

Query: 323 VHASK 327
            H  +
Sbjct: 495 NHTGE 499



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 69/240 (28%), Positives = 91/240 (37%), Gaps = 42/240 (17%)

Query: 489 PEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH 548
           PEG        C  CGKSF     L +H R+HTGERPY CP C    +Q  +L  HL+ H
Sbjct: 272 PEGPGEPRQFICNECGKSFTWWSSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNH 331

Query: 549 HREQRSGAGPGPPPEPPPPSQRGSAPQS-----------GAKPSPQPATWV--------- 588
                     G  P P P   RG   +            GA+ +P P+            
Sbjct: 332 ---------TGERPHPCPHCGRGFRQKQHLLKHLRTHLPGAQAAPCPSCGKSCRSRAALR 382

Query: 589 --EGASSPRPPSSGAG-PGSR-RKPASPGRTLRNGRGGEAEP--LDLSLRAGPGGEAGPG 642
             + A +   P+  AG PG + +  A PG   R  R  +  P   D     G  G AGPG
Sbjct: 383 AHQRAHAVAEPAVPAGEPGDQPQAEAIPGLAAR-PRSSQRSPGARDTLWGRGQAGLAGPG 441

Query: 643 GALH-RCLFCPFATGAPELMALHLQVHHSRRAR-----GRRPPQADASPPYARVPSGETP 696
                 C  C  +      + +H ++H   R       GRR  Q      + R  +GE P
Sbjct: 442 EPRQFICNECGKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNLTRHRRNHTGERP 501



 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 44/140 (31%), Positives = 61/140 (43%), Gaps = 10/140 (7%)

Query: 4   SRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAG------ERRF 57
           + P  P+G     P A      +   +  P  S  S G     W   +AG       R+F
Sbjct: 391 AEPAVPAGEPGDQPQAEA----IPGLAARPRSSQRSPGARDTLWGRGQAGLAGPGEPRQF 446

Query: 58  PCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAA 117
            C  CGK F + S L +H R H G + + CP CG R +Q+  L  H R H  ERP    A
Sbjct: 447 ICNECGKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNLTRHRRNHTGERPYLCPA 506

Query: 118 RLLLELEERALLREARLGRA 137
                 +++ LL+  R+ RA
Sbjct: 507 CGRGFSQKQHLLKHQRVHRA 526



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 40/117 (34%), Positives = 49/117 (41%), Gaps = 11/117 (9%)

Query: 438 ETWARGRSLGSLA-SLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGAT 496
           +T  R R+LG    S  PR        A  AG    S +         G   P    G  
Sbjct: 55  QTMGRPRALGGQEESGSPRWAPPTEQDAGLAGRAPGSAS---------GPLSPSLSSGEG 105

Query: 497 GKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQR 553
              C  CGK F     LK+H R HTGE+PY C  C  + +Q  +L  H QRHH  +R
Sbjct: 106 HFVCLDCGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARH-QRHHTGER 161



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 31/115 (26%), Positives = 43/115 (37%), Gaps = 19/115 (16%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHRE-QRSGAG- 557
           CP C + F    HL  H + H+    + CP C+        L+ H + H R+ Q S AG 
Sbjct: 165 CPECARRFSQKQHLLKHQKTHSRPATHSCPECERCFRHQVGLRIHQRAHARDRQGSRAGL 224

Query: 558 ----------------PGPPPEPPPPSQRGSAPQSGAKPSPQPA-TWVEGASSPR 595
                           PGPP   P  +  G       +P  + A +  EG   PR
Sbjct: 225 HELIQDAAARRACRLQPGPPRGRPEWAWLGLCQGWWGQPGARAAVSGPEGPGEPR 279



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 29/109 (26%), Positives = 40/109 (36%), Gaps = 7/109 (6%)

Query: 226 PPPQPQPQPPPQPEPRSVPQPEPEPEPEREA-----TPTPA--PAAPEEPPAPPEFRCQV 278
           PP Q   +P           P   P  E++A      P  A  P +P        F C  
Sbjct: 52  PPRQTMGRPRALGGQEESGSPRWAPPTEQDAGLAGRAPGSASGPLSPSLSSGEGHFVCLD 111

Query: 279 CGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
           CG+ F+    LK H R H     + C  CG+ F +   L  H + H  +
Sbjct: 112 CGKRFSWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHHTGE 160


>gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score =  124 bits (311), Expect = 3e-28
 Identities = 146/542 (26%), Positives = 199/542 (36%), Gaps = 79/542 (14%)

Query: 44  AVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSH 103
           +V+ S ++A  R   C  C + F     L LH R         CP CG R      L  H
Sbjct: 44  SVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALH 103

Query: 104 LRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAF 163
            + H    P    A  L     R  +      RA S+             RP A      
Sbjct: 104 RQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAA-----------KRPIA------ 146

Query: 164 RCPYCKGKFRTSAERERHLHILH------RPWKCGLCSFGSSQEEELLHHSLTAHGAPER 217
            CP C+ +F    +   HL   H      RP+ CG C    +Q ++L+ H          
Sbjct: 147 -CPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALE 205

Query: 218 PLAATSAAPPPQPQPQ-PPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE-PPAPPEFR 275
             AA +  P P+ +P    P+P   +V +P       +     P   A           +
Sbjct: 206 EAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQ 265

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLR-AP 334
           C  CG+ FT   +L  H R H     + C  CGR F+    L +H K+H    G  + AP
Sbjct: 266 CPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAP 325

Query: 335 GPAS-----GPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERRE----PPSLLG----- 380
           GP S     GP  +   P   +    PL PA    P   P   ++    PPSL       
Sbjct: 326 GPGSPQLPAGPQESAAEPTPAV----PLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCG 381

Query: 381 -----YLSLRAGEGRPNGEG----AEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEE 431
                   LRA + +  GE     AE   G++FG      + L A +R H  E P   EE
Sbjct: 382 RSFRLERFLRAHQRQHTGERPFTCAE--CGKNFG----KKTHLVAHSRVHSGERPFACEE 435

Query: 432 VVEAEEETWARGRSLGSLASLHPRPGEGPGHS--ASAAGAQARSTATQEENGLLVGGTRP 489
                     R  S GS  + H R    P         G   R       +  +  G +P
Sbjct: 436 C--------GRRFSQGSHLAAH-RRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKP 486

Query: 490 EGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHH 549
                     CP CGK+F    +L  H R+HTGERPY CP CD + +Q  +L  H + H 
Sbjct: 487 --------YVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHI 538

Query: 550 RE 551
           R+
Sbjct: 539 RD 540



 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 87/331 (26%), Positives = 110/331 (33%), Gaps = 74/331 (22%)

Query: 33  PAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGH 92
           PAV+A   G  AV        +R F C  CGKRFR    L  H R H G +  QCP CG 
Sbjct: 220 PAVTAPRPGGDAV--------DRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGK 271

Query: 93  RAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGL 152
           R   +  L SH R H  E+P  P          +  L        RS G  QA P     
Sbjct: 272 RFTNKPYLTSHRRIHTGEKP-YPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSP 330

Query: 153 ARPQAPSSSA----------------------------------FRCPYCKGKFRTSAER 178
             P  P  SA                                  + C  C   FR     
Sbjct: 331 QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFL 390

Query: 179 ERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPP 236
             H   H   RP+ C  C     ++  L+ HS    G  ERP A                
Sbjct: 391 RAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSG--ERPFACEECG----------- 437

Query: 237 QPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296
               R   Q        R+        AP+ P     F C  CG++F    +L  H R H
Sbjct: 438 ----RRFSQGSHLAAHRRD-------HAPDRP-----FVCPDCGKAFRHKPYLAAHRRIH 481

Query: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
                + CP CG+ F +   L +H ++H  +
Sbjct: 482 TGEKPYVCPDCGKAFSQKSNLVSHRRIHTGE 512



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 111/416 (26%), Positives = 145/416 (34%), Gaps = 62/416 (14%)

Query: 275 RCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAP 334
           RC  C + F     L  H R+ +A     CP CGR F+   FL  H +VHA+    L   
Sbjct: 58  RCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFA 117

Query: 335 GPASGPA-RAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNG 393
               G + R      L L A+      +          RR+         LRA   R + 
Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRK--------QLRAHLRRCHP 169

Query: 394 EGAEPGP------GRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARG---R 444
              E  P      GRSF  +      L A  R H          V EA EE  A+    R
Sbjct: 170 PAPEARPFICGNCGRSFAQW----DQLVAHKRVH----------VAEALEEAAAKALGPR 215

Query: 445 SLGSLASLHPRPGEGP---GHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCP 501
             G  A   PRPG          +  G + R       +  +  G RP          CP
Sbjct: 216 PRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPH--------QCP 267

Query: 502 FCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ---RSGAGP 558
            CGK F +  +L  H R+HTGE+PY C  C        +L  H + H R +   ++  GP
Sbjct: 268 ECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGP 327

Query: 559 GPPPEPPPPSQRGSAPQSGA--KPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTL 616
           G P  P  P +  + P      KP+ +P     GA    P      P S       GR+ 
Sbjct: 328 GSPQLPAGPQESAAEPTPAVPLKPAQEPP---PGAPPEHPQDPIEAPPSLYSCDDCGRSF 384

Query: 617 RNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRR 672
           R         L+  LRA      G       C  C    G    +  H +VH   R
Sbjct: 385 R---------LERFLRAHQRQHTGE--RPFTCAECGKNFGKKTHLVAHSRVHSGER 429



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 31/74 (41%), Positives = 38/74 (51%)

Query: 39  SLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRA 98
           S G    +     A +R F CP CGK FR    LA H R H G + + CP CG   +Q++
Sbjct: 441 SQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKS 500

Query: 99  LLRSHLRTHQPERP 112
            L SH R H  ERP
Sbjct: 501 NLVSHRRIHTGERP 514



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 21/63 (33%), Positives = 27/63 (42%)

Query: 45  VSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHL 104
           VS      GER + CP C + F   S L  H ++H    AF C  CG        L +H 
Sbjct: 503 VSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQ 562

Query: 105 RTH 107
           + H
Sbjct: 563 KKH 565


>gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score =  124 bits (311), Expect = 3e-28
 Identities = 146/542 (26%), Positives = 199/542 (36%), Gaps = 79/542 (14%)

Query: 44  AVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSH 103
           +V+ S ++A  R   C  C + F     L LH R         CP CG R      L  H
Sbjct: 44  SVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALH 103

Query: 104 LRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAF 163
            + H    P    A  L     R  +      RA S+             RP A      
Sbjct: 104 RQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAA-----------KRPIA------ 146

Query: 164 RCPYCKGKFRTSAERERHLHILH------RPWKCGLCSFGSSQEEELLHHSLTAHGAPER 217
            CP C+ +F    +   HL   H      RP+ CG C    +Q ++L+ H          
Sbjct: 147 -CPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALE 205

Query: 218 PLAATSAAPPPQPQPQ-PPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE-PPAPPEFR 275
             AA +  P P+ +P    P+P   +V +P       +     P   A           +
Sbjct: 206 EAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQ 265

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLR-AP 334
           C  CG+ FT   +L  H R H     + C  CGR F+    L +H K+H    G  + AP
Sbjct: 266 CPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAP 325

Query: 335 GPAS-----GPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERRE----PPSLLG----- 380
           GP S     GP  +   P   +    PL PA    P   P   ++    PPSL       
Sbjct: 326 GPGSPQLPAGPQESAAEPTPAV----PLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCG 381

Query: 381 -----YLSLRAGEGRPNGEG----AEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEE 431
                   LRA + +  GE     AE   G++FG      + L A +R H  E P   EE
Sbjct: 382 RSFRLERFLRAHQRQHTGERPFTCAE--CGKNFG----KKTHLVAHSRVHSGERPFACEE 435

Query: 432 VVEAEEETWARGRSLGSLASLHPRPGEGPGHS--ASAAGAQARSTATQEENGLLVGGTRP 489
                     R  S GS  + H R    P         G   R       +  +  G +P
Sbjct: 436 C--------GRRFSQGSHLAAH-RRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKP 486

Query: 490 EGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHH 549
                     CP CGK+F    +L  H R+HTGERPY CP CD + +Q  +L  H + H 
Sbjct: 487 --------YVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHI 538

Query: 550 RE 551
           R+
Sbjct: 539 RD 540



 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 87/331 (26%), Positives = 110/331 (33%), Gaps = 74/331 (22%)

Query: 33  PAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGH 92
           PAV+A   G  AV        +R F C  CGKRFR    L  H R H G +  QCP CG 
Sbjct: 220 PAVTAPRPGGDAV--------DRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGK 271

Query: 93  RAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGL 152
           R   +  L SH R H  E+P  P          +  L        RS G  QA P     
Sbjct: 272 RFTNKPYLTSHRRIHTGEKP-YPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSP 330

Query: 153 ARPQAPSSSA----------------------------------FRCPYCKGKFRTSAER 178
             P  P  SA                                  + C  C   FR     
Sbjct: 331 QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFL 390

Query: 179 ERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPP 236
             H   H   RP+ C  C     ++  L+ HS    G  ERP A                
Sbjct: 391 RAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSG--ERPFACEECG----------- 437

Query: 237 QPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296
               R   Q        R+        AP+ P     F C  CG++F    +L  H R H
Sbjct: 438 ----RRFSQGSHLAAHRRD-------HAPDRP-----FVCPDCGKAFRHKPYLAAHRRIH 481

Query: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
                + CP CG+ F +   L +H ++H  +
Sbjct: 482 TGEKPYVCPDCGKAFSQKSNLVSHRRIHTGE 512



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 111/416 (26%), Positives = 145/416 (34%), Gaps = 62/416 (14%)

Query: 275 RCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAP 334
           RC  C + F     L  H R+ +A     CP CGR F+   FL  H +VHA+    L   
Sbjct: 58  RCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFA 117

Query: 335 GPASGPA-RAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNG 393
               G + R      L L A+      +          RR+         LRA   R + 
Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRK--------QLRAHLRRCHP 169

Query: 394 EGAEPGP------GRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARG---R 444
              E  P      GRSF  +      L A  R H          V EA EE  A+    R
Sbjct: 170 PAPEARPFICGNCGRSFAQW----DQLVAHKRVH----------VAEALEEAAAKALGPR 215

Query: 445 SLGSLASLHPRPGEGP---GHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCP 501
             G  A   PRPG          +  G + R       +  +  G RP          CP
Sbjct: 216 PRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPH--------QCP 267

Query: 502 FCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ---RSGAGP 558
            CGK F +  +L  H R+HTGE+PY C  C        +L  H + H R +   ++  GP
Sbjct: 268 ECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGP 327

Query: 559 GPPPEPPPPSQRGSAPQSGA--KPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTL 616
           G P  P  P +  + P      KP+ +P     GA    P      P S       GR+ 
Sbjct: 328 GSPQLPAGPQESAAEPTPAVPLKPAQEPP---PGAPPEHPQDPIEAPPSLYSCDDCGRSF 384

Query: 617 RNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRR 672
           R         L+  LRA      G       C  C    G    +  H +VH   R
Sbjct: 385 R---------LERFLRAHQRQHTGE--RPFTCAECGKNFGKKTHLVAHSRVHSGER 429



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 31/74 (41%), Positives = 38/74 (51%)

Query: 39  SLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRA 98
           S G    +     A +R F CP CGK FR    LA H R H G + + CP CG   +Q++
Sbjct: 441 SQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKS 500

Query: 99  LLRSHLRTHQPERP 112
            L SH R H  ERP
Sbjct: 501 NLVSHRRIHTGERP 514



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 21/63 (33%), Positives = 27/63 (42%)

Query: 45  VSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHL 104
           VS      GER + CP C + F   S L  H ++H    AF C  CG        L +H 
Sbjct: 503 VSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQ 562

Query: 105 RTH 107
           + H
Sbjct: 563 KKH 565


>gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]
          Length = 624

 Score =  124 bits (311), Expect = 3e-28
 Identities = 146/542 (26%), Positives = 199/542 (36%), Gaps = 79/542 (14%)

Query: 44  AVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSH 103
           +V+ S ++A  R   C  C + F     L LH R         CP CG R      L  H
Sbjct: 101 SVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALH 160

Query: 104 LRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAF 163
            + H    P    A  L     R  +      RA S+             RP A      
Sbjct: 161 RQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAA-----------KRPIA------ 203

Query: 164 RCPYCKGKFRTSAERERHLHILH------RPWKCGLCSFGSSQEEELLHHSLTAHGAPER 217
            CP C+ +F    +   HL   H      RP+ CG C    +Q ++L+ H          
Sbjct: 204 -CPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALE 262

Query: 218 PLAATSAAPPPQPQPQ-PPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE-PPAPPEFR 275
             AA +  P P+ +P    P+P   +V +P       +     P   A           +
Sbjct: 263 EAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQ 322

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLR-AP 334
           C  CG+ FT   +L  H R H     + C  CGR F+    L +H K+H    G  + AP
Sbjct: 323 CPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAP 382

Query: 335 GPAS-----GPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERRE----PPSLLG----- 380
           GP S     GP  +   P   +    PL PA    P   P   ++    PPSL       
Sbjct: 383 GPGSPQLPAGPQESAAEPTPAV----PLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCG 438

Query: 381 -----YLSLRAGEGRPNGEG----AEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEE 431
                   LRA + +  GE     AE   G++FG      + L A +R H  E P   EE
Sbjct: 439 RSFRLERFLRAHQRQHTGERPFTCAE--CGKNFG----KKTHLVAHSRVHSGERPFACEE 492

Query: 432 VVEAEEETWARGRSLGSLASLHPRPGEGPGHS--ASAAGAQARSTATQEENGLLVGGTRP 489
                     R  S GS  + H R    P         G   R       +  +  G +P
Sbjct: 493 C--------GRRFSQGSHLAAH-RRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKP 543

Query: 490 EGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHH 549
                     CP CGK+F    +L  H R+HTGERPY CP CD + +Q  +L  H + H 
Sbjct: 544 --------YVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHI 595

Query: 550 RE 551
           R+
Sbjct: 596 RD 597



 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 87/331 (26%), Positives = 110/331 (33%), Gaps = 74/331 (22%)

Query: 33  PAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGH 92
           PAV+A   G  AV        +R F C  CGKRFR    L  H R H G +  QCP CG 
Sbjct: 277 PAVTAPRPGGDAV--------DRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGK 328

Query: 93  RAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGL 152
           R   +  L SH R H  E+P  P          +  L        RS G  QA P     
Sbjct: 329 RFTNKPYLTSHRRIHTGEKP-YPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSP 387

Query: 153 ARPQAPSSSA----------------------------------FRCPYCKGKFRTSAER 178
             P  P  SA                                  + C  C   FR     
Sbjct: 388 QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFL 447

Query: 179 ERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPP 236
             H   H   RP+ C  C     ++  L+ HS    G  ERP A                
Sbjct: 448 RAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSG--ERPFACEECG----------- 494

Query: 237 QPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296
               R   Q        R+        AP+ P     F C  CG++F    +L  H R H
Sbjct: 495 ----RRFSQGSHLAAHRRD-------HAPDRP-----FVCPDCGKAFRHKPYLAAHRRIH 538

Query: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
                + CP CG+ F +   L +H ++H  +
Sbjct: 539 TGEKPYVCPDCGKAFSQKSNLVSHRRIHTGE 569



 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 135/524 (25%), Positives = 183/524 (34%), Gaps = 80/524 (15%)

Query: 170 GKFRTSAERERHLHILHRPWKCG---LCSFGSSQEEELLHHSLTAHGAPERPLAATSAAP 226
           G+ R  +      +I  R WK     LCS   ++EE +L            PLA   A P
Sbjct: 22  GRSRRCSRGSIPRNIPKRSWKKPHPQLCSL-QAEEEPMLERRCRG------PLAMGLAQP 74

Query: 227 PPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQS 286
                P    Q  P+++ +   E    R+   + A +  + P      RC  C + F   
Sbjct: 75  RLLSGPS---QESPQTLGK---ESRGLRQQGTSVAQSGAQAPGRA--HRCAHCRRHFPGW 126

Query: 287 WFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPA-RAPQ 345
             L  H R+ +A     CP CGR F+   FL  H +VHA+    L       G + R   
Sbjct: 127 VALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWV 186

Query: 346 PPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGP----- 400
              L L A+      +          RR+         LRA   R +    E  P     
Sbjct: 187 ALVLHLRAHSAAKRPIACPKCERRFWRRK--------QLRAHLRRCHPPAPEARPFICGN 238

Query: 401 -GRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARG---RSLGSLASLHPRP 456
            GRSF  +      L A  R H          V EA EE  A+    R  G  A   PRP
Sbjct: 239 CGRSFAQW----DQLVAHKRVH----------VAEALEEAAAKALGPRPRGRPAVTAPRP 284

Query: 457 GEGP---GHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHL 513
           G          +  G + R       +  +  G RP          CP CGK F +  +L
Sbjct: 285 GGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPH--------QCPECGKRFTNKPYL 336

Query: 514 KVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ---RSGAGPGPPPEPPPPSQR 570
             H R+HTGE+PY C  C        +L  H + H R +   ++  GPG P  P  P + 
Sbjct: 337 TSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQES 396

Query: 571 GSAPQSGA--KPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEPLD 628
            + P      KP+ +P     GA    P      P S       GR+ R         L+
Sbjct: 397 AAEPTPAVPLKPAQEPP---PGAPPEHPQDPIEAPPSLYSCDDCGRSFR---------LE 444

Query: 629 LSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRR 672
             LRA      G       C  C    G    +  H +VH   R
Sbjct: 445 RFLRAHQRQHTGE--RPFTCAECGKNFGKKTHLVAHSRVHSGER 486



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 31/74 (41%), Positives = 38/74 (51%)

Query: 39  SLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRA 98
           S G    +     A +R F CP CGK FR    LA H R H G + + CP CG   +Q++
Sbjct: 498 SQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKS 557

Query: 99  LLRSHLRTHQPERP 112
            L SH R H  ERP
Sbjct: 558 NLVSHRRIHTGERP 571



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 21/63 (33%), Positives = 27/63 (42%)

Query: 45  VSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHL 104
           VS      GER + CP C + F   S L  H ++H    AF C  CG        L +H 
Sbjct: 560 VSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQ 619

Query: 105 RTH 107
           + H
Sbjct: 620 KKH 622


>gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score =  124 bits (311), Expect = 3e-28
 Identities = 146/542 (26%), Positives = 199/542 (36%), Gaps = 79/542 (14%)

Query: 44  AVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSH 103
           +V+ S ++A  R   C  C + F     L LH R         CP CG R      L  H
Sbjct: 44  SVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALH 103

Query: 104 LRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAF 163
            + H    P    A  L     R  +      RA S+             RP A      
Sbjct: 104 RQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAA-----------KRPIA------ 146

Query: 164 RCPYCKGKFRTSAERERHLHILH------RPWKCGLCSFGSSQEEELLHHSLTAHGAPER 217
            CP C+ +F    +   HL   H      RP+ CG C    +Q ++L+ H          
Sbjct: 147 -CPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALE 205

Query: 218 PLAATSAAPPPQPQPQ-PPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEE-PPAPPEFR 275
             AA +  P P+ +P    P+P   +V +P       +     P   A           +
Sbjct: 206 EAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQ 265

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLR-AP 334
           C  CG+ FT   +L  H R H     + C  CGR F+    L +H K+H    G  + AP
Sbjct: 266 CPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAP 325

Query: 335 GPAS-----GPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERRE----PPSLLG----- 380
           GP S     GP  +   P   +    PL PA    P   P   ++    PPSL       
Sbjct: 326 GPGSPQLPAGPQESAAEPTPAV----PLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCG 381

Query: 381 -----YLSLRAGEGRPNGEG----AEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEE 431
                   LRA + +  GE     AE   G++FG      + L A +R H  E P   EE
Sbjct: 382 RSFRLERFLRAHQRQHTGERPFTCAE--CGKNFG----KKTHLVAHSRVHSGERPFACEE 435

Query: 432 VVEAEEETWARGRSLGSLASLHPRPGEGPGHS--ASAAGAQARSTATQEENGLLVGGTRP 489
                     R  S GS  + H R    P         G   R       +  +  G +P
Sbjct: 436 C--------GRRFSQGSHLAAH-RRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKP 486

Query: 490 EGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHH 549
                     CP CGK+F    +L  H R+HTGERPY CP CD + +Q  +L  H + H 
Sbjct: 487 --------YVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHI 538

Query: 550 RE 551
           R+
Sbjct: 539 RD 540



 Score = 97.8 bits (242), Expect = 3e-20
 Identities = 87/331 (26%), Positives = 110/331 (33%), Gaps = 74/331 (22%)

Query: 33  PAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGH 92
           PAV+A   G  AV        +R F C  CGKRFR    L  H R H G +  QCP CG 
Sbjct: 220 PAVTAPRPGGDAV--------DRPFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGK 271

Query: 93  RAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGL 152
           R   +  L SH R H  E+P  P          +  L        RS G  QA P     
Sbjct: 272 RFTNKPYLTSHRRIHTGEKP-YPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSP 330

Query: 153 ARPQAPSSSA----------------------------------FRCPYCKGKFRTSAER 178
             P  P  SA                                  + C  C   FR     
Sbjct: 331 QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFL 390

Query: 179 ERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPP 236
             H   H   RP+ C  C     ++  L+ HS    G  ERP A                
Sbjct: 391 RAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSG--ERPFACEECG----------- 437

Query: 237 QPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296
               R   Q        R+        AP+ P     F C  CG++F    +L  H R H
Sbjct: 438 ----RRFSQGSHLAAHRRD-------HAPDRP-----FVCPDCGKAFRHKPYLAAHRRIH 481

Query: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
                + CP CG+ F +   L +H ++H  +
Sbjct: 482 TGEKPYVCPDCGKAFSQKSNLVSHRRIHTGE 512



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 111/416 (26%), Positives = 145/416 (34%), Gaps = 62/416 (14%)

Query: 275 RCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAP 334
           RC  C + F     L  H R+ +A     CP CGR F+   FL  H +VHA+    L   
Sbjct: 58  RCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFA 117

Query: 335 GPASGPA-RAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNG 393
               G + R      L L A+      +          RR+         LRA   R + 
Sbjct: 118 CHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRK--------QLRAHLRRCHP 169

Query: 394 EGAEPGP------GRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARG---R 444
              E  P      GRSF  +      L A  R H          V EA EE  A+    R
Sbjct: 170 PAPEARPFICGNCGRSFAQW----DQLVAHKRVH----------VAEALEEAAAKALGPR 215

Query: 445 SLGSLASLHPRPGEGP---GHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCP 501
             G  A   PRPG          +  G + R       +  +  G RP          CP
Sbjct: 216 PRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERPH--------QCP 267

Query: 502 FCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ---RSGAGP 558
            CGK F +  +L  H R+HTGE+PY C  C        +L  H + H R +   ++  GP
Sbjct: 268 ECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGP 327

Query: 559 GPPPEPPPPSQRGSAPQSGA--KPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTL 616
           G P  P  P +  + P      KP+ +P     GA    P      P S       GR+ 
Sbjct: 328 GSPQLPAGPQESAAEPTPAVPLKPAQEPP---PGAPPEHPQDPIEAPPSLYSCDDCGRSF 384

Query: 617 RNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRR 672
           R         L+  LRA      G       C  C    G    +  H +VH   R
Sbjct: 385 R---------LERFLRAHQRQHTGE--RPFTCAECGKNFGKKTHLVAHSRVHSGER 429



 Score = 63.2 bits (152), Expect = 8e-10
 Identities = 31/74 (41%), Positives = 38/74 (51%)

Query: 39  SLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRA 98
           S G    +     A +R F CP CGK FR    LA H R H G + + CP CG   +Q++
Sbjct: 441 SQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKS 500

Query: 99  LLRSHLRTHQPERP 112
            L SH R H  ERP
Sbjct: 501 NLVSHRRIHTGERP 514



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 21/63 (33%), Positives = 27/63 (42%)

Query: 45  VSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHL 104
           VS      GER + CP C + F   S L  H ++H    AF C  CG        L +H 
Sbjct: 503 VSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQ 562

Query: 105 RTH 107
           + H
Sbjct: 563 KKH 565


>gi|110681708 zinc finger protein 579 [Homo sapiens]
          Length = 562

 Score =  118 bits (295), Expect = 2e-26
 Identities = 144/582 (24%), Positives = 194/582 (33%), Gaps = 138/582 (23%)

Query: 58  PCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAA 117
           PCP CG+ FRF   L+ H  +H G +   CP C     + A L  HLR H P+ P   AA
Sbjct: 45  PCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGPQPPLRCAA 104

Query: 118 RLLLELEERALLREARLGR--ARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGK---- 171
                   R     A+L R  A+   G +   A E +A+  A  S     P  +G     
Sbjct: 105 C------PRTFPEPAQLRRHLAQEHAGGEVELAIERVAKETAEPSWG---PQDEGSEPPT 155

Query: 172 -FRTSAERERHLHILHRPWKCG---LCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPP 227
                A  E  +      W  G     +  +S  E     S  A        A  + A  
Sbjct: 156 TAAAGATEEEAVAAWPETWPAGEPSTLAAPTSAAEPRESESEEAEAGAAELRAELALAAG 215

Query: 228 PQPQPQPPPQP-----------------EPRSVPQPEPEPEPEREATPTPAPAAPEEPPA 270
            Q + Q   Q                  E ++ P   PE E E E  P         PP 
Sbjct: 216 RQEEKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQEGEGGP---------PPR 266

Query: 271 PPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGP 330
           P   +C +C ++F + W L  H   H       CP CG  F+   +L+ H +VH      
Sbjct: 267 PKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASYLRQHRRVH------ 320

Query: 331 LRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGR 390
                                      GP  LLAP P   ++ +  S     +  + +G 
Sbjct: 321 ---------------------------GPLSLLAPLPAAGKKDDKAS----GARNSAKGP 349

Query: 391 PNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLA 450
             GEGAE G G S GG                                    G++ G  A
Sbjct: 350 EGGEGAECG-GASEGG-----------------------------------EGQNGGDAA 373

Query: 451 SLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSA 510
              P  GE P       G   R  A   ++G+   G RP          C  C + F+  
Sbjct: 374 PARPPAGE-PRFWCPECGKGFRRRAHLRQHGVTHSGARP--------FQCVRCQREFKRL 424

Query: 511 HHLKVHLRVHT-GERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGA--------GPGPP 561
             L  H +VH  G  P+ CP C    +++ SL  H + H  E    A         P  P
Sbjct: 425 ADLARHAQVHAGGPAPHPCPRCPRRFSRAYSLLRHQRCHRAELERAAALQALQAQAPTSP 484

Query: 562 PEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGP 603
           P PPPP +  +  +    P P      E  S   PP S   P
Sbjct: 485 PPPPPPLK--AEQEEEGLPLPLANIKEEPPSPGTPPQSPPAP 524



 Score =  100 bits (250), Expect = 4e-21
 Identities = 140/559 (25%), Positives = 187/559 (33%), Gaps = 134/559 (23%)

Query: 230 PQPQPPPQPEP--RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSW 287
           PQP PP Q  P  R   +                  AP  P       C  CG+ F   +
Sbjct: 3   PQPPPPAQGSPPHRGRGRGRGRGRGRGRGRGRGGAGAPRAP-----LPCPTCGRLFRFPY 57

Query: 288 FLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPP 347
           +L  H   H     HACP+C + F+ P  L  H++ H  +  PLR    A+ P   P+P 
Sbjct: 58  YLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGPQ-PPLRC---AACPRTFPEPA 113

Query: 348 DLGL-LAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGG 406
            L   LA E  G  + LA      E  EP               P  EG+EP        
Sbjct: 114 QLRRHLAQEHAGGEVELAIERVAKETAEP------------SWGPQDEGSEP-------- 153

Query: 407 FRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRS---LGSLASLHPRPGEGPGHS 463
             P ++A  A            EEE V A  ETW  G         ++  PR  E     
Sbjct: 154 --PTTAAAGA-----------TEEEAVAAWPETWPAGEPSTLAAPTSAAEPRESESEEAE 200

Query: 464 ASAAGAQAR---STATQEENGLLVGG------------------------TRPEGGRGAT 496
           A AA  +A    +   QEE  +L+                           RPEG +   
Sbjct: 201 AGAAELRAELALAAGRQEEKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQEGE 260

Query: 497 G--------KDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH 548
           G          C  C K+F     L  H  VH+ +RP+ CP C         L + L  +
Sbjct: 261 GGPPPRPKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDC--------GLAFRLASY 312

Query: 549 HREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGA----------------S 592
            R+ R   GP     P P + +     SGA+ S +     EGA                +
Sbjct: 313 LRQHRRVHGPLSLLAPLPAAGKKDDKASGARNSAKGPEGGEGAECGGASEGGEGQNGGDA 372

Query: 593 SPRPPSSG--------AGPGSRRKP-----------ASPGRTLRNGRGGEAEPLDLSLRA 633
           +P  P +G         G G RR+            A P + +R  R  E + L    R 
Sbjct: 373 APARPPAGEPRFWCPECGKGFRRRAHLRQHGVTHSGARPFQCVRCQR--EFKRLADLARH 430

Query: 634 GPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRPPQADASPPYARVPSG 693
                 GP  A H C  CP        +  H + H +   R        A  P +  P  
Sbjct: 431 AQVHAGGP--APHPCPRCPRRFSRAYSLLRHQRCHRAELERAAALQALQAQAPTSPPP-- 486

Query: 694 ETPPSPSQEGEEGSGLSRP 712
             PP P +  +E  GL  P
Sbjct: 487 --PPPPLKAEQEEEGLPLP 503



 Score = 73.6 bits (179), Expect = 6e-13
 Identities = 74/279 (26%), Positives = 96/279 (34%), Gaps = 50/279 (17%)

Query: 55  RRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRS 114
           +R  C +C K F     L+ H   H   + F CP CG      + LR H R H P    +
Sbjct: 268 KRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASYLRQHRRVHGPLSLLA 327

Query: 115 PAARLLLELEERALLREARLGR---------ARSSGGMQATPATEGLARPQAPSSSAFRC 165
           P      + ++ +  R +  G            S GG          ARP A     F C
Sbjct: 328 PLPAAGKKDDKASGARNSAKGPEGGEGAECGGASEGGEGQNGGDAAPARPPA-GEPRFWC 386

Query: 166 PYCKGKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAP-------- 215
           P C   FR  A   +H   H   RP++C  C     +  +L  H+    G P        
Sbjct: 387 PECGKGFRRRAHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAGGPAPHPCPRC 446

Query: 216 ---------------------ERPLA--ATSAAPPPQPQPQPPP---QPEPRSVPQPEPE 249
                                ER  A  A  A  P  P P PPP   + E   +P P   
Sbjct: 447 PRRFSRAYSLLRHQRCHRAELERAAALQALQAQAPTSPPPPPPPLKAEQEEEGLPLPLAN 506

Query: 250 PEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWF 288
            + E  +  TP    P+ PPAPP F    C  S   S F
Sbjct: 507 IKEEPPSPGTP----PQSPPAPPVFLSASCFDSQDHSAF 541



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 72/250 (28%), Positives = 87/250 (34%), Gaps = 59/250 (23%)

Query: 5   RPRAPSGHLAPSPPAF---DGELDLQRYSNGPAVSAGSLGMGAVSWSESR---------- 51
           R   P   LAP P A    D     +  + GP    G+   GA    E +          
Sbjct: 318 RVHGPLSLLAPLPAAGKKDDKASGARNSAKGPEGGEGAECGGASEGGEGQNGGDAAPARP 377

Query: 52  -AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPE 110
            AGE RF CP CGK FR  + L  H   H GA+ FQC  C     + A L  H + H   
Sbjct: 378 PAGEPRFWCPECGKGFRRRAHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAGG 437

Query: 111 RPRSPAARLLLELEER-ALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCK 169
               P  R         +LLR  R  RA     ++   A + L + QAP+S     P  K
Sbjct: 438 PAPHPCPRCPRRFSRAYSLLRHQRCHRAE----LERAAALQAL-QAQAPTSPPPPPPPLK 492

Query: 170 GKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPP-P 228
                                       + QEEE         G P  PLA     PP P
Sbjct: 493 ----------------------------AEQEEE---------GLP-LPLANIKEEPPSP 514

Query: 229 QPQPQPPPQP 238
              PQ PP P
Sbjct: 515 GTPPQSPPAP 524


>gi|14249488 zinc finger and SCAN domain containing 10 [Homo
           sapiens]
          Length = 725

 Score =  117 bits (293), Expect = 4e-26
 Identities = 139/504 (27%), Positives = 181/504 (35%), Gaps = 97/504 (19%)

Query: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQP 109
           S    R F C  CGK F  +SIL LH+R H   +   C  CGHR  Q + L  HL TH  
Sbjct: 314 SHPAGRSFLCLCCGKSFGRSSILKLHMRTHTDERPHACHLCGHRFRQSSHLSKHLLTHSS 373

Query: 110 ERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCK 169
           E P    A      + RA L +  L  A+        P     ++ +AP  +   C +C 
Sbjct: 374 E-PAFLCAECGRGFQRRASLVQHLLAHAQDQ-----KPPCAPESKAEAPPLTDVLCSHCG 427

Query: 170 GKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQ 229
             F+  +  +RHL I H   K    S GS               +  RP   +       
Sbjct: 428 QSFQRRSSLKRHLRI-HARDKDRRSSEGSGSRRR---------DSDRRPFVCSDCG---- 473

Query: 230 PQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFL 289
                      ++  + E      R  T        E P     F CQ CG+SFTQS  L
Sbjct: 474 -----------KAFRRSEHLVAHRRVHTG-------ERP-----FSCQACGRSFTQSSQL 510

Query: 290 KGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDL 349
             H R H     +ACP CG+ F     L  H+  H    GP        G +   Q  DL
Sbjct: 511 VSHQRVHTGEKPYACPQCGKRFVRRASLARHLLTHG---GPRPHHCTQCGKSFG-QTQDL 566

Query: 350 GLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRP 409
                                  R   S  G    R  E    GEG              
Sbjct: 567 A----------------------RHQRSHTGEKPCRCSEC---GEGFSQ----------- 590

Query: 410 LSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRP--GEGPGHSASAA 467
            S+ L    R H  E+P        A +    R R+  +LA  H R   GE P +S    
Sbjct: 591 -SAHLARHQRIHTGEKPH-------ACDTCGHRFRNSSNLAR-HRRSHTGERP-YSCQTC 640

Query: 468 GAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYK 527
           G   R  A    +  L     P   +    ++C  CGKSF  + +L  HL VHTG RPY 
Sbjct: 641 GRSFRRNAHLRRH--LATHAEPGQEQAEPPQECVECGKSFSRSCNLLRHLLVHTGARPYS 698

Query: 528 CPHCDYAGTQSGSLKYHLQRHHRE 551
           C  C  + +++  L  HL+ H RE
Sbjct: 699 CTQCGRSFSRNSHLLRHLRTHARE 722



 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 73/285 (25%), Positives = 96/285 (33%), Gaps = 79/285 (27%)

Query: 45  VSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHL 104
           VS      GE+ + CP CGKRF   + LA HL  H G +   C  CG    Q   L  H 
Sbjct: 511 VSHQRVHTGEKPYACPQCGKRFVRRASLARHLLTHGGPRPHHCTQCGKSFGQTQDLARHQ 570

Query: 105 RTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQA--PSSSA 162
           R+H  E+P                         R S   +    +  LAR Q        
Sbjct: 571 RSHTGEKP------------------------CRCSECGEGFSQSAHLARHQRIHTGEKP 606

Query: 163 FRCPYCKGKFRTSAE--RERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLA 220
             C  C  +FR S+   R R  H   RP+ C  C     +   L  H L  H        
Sbjct: 607 HACDTCGHRFRNSSNLARHRRSHTGERPYSCQTCGRSFRRNAHLRRH-LATH-------- 657

Query: 221 ATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCG 280
               A P Q Q +PP +                                      C  CG
Sbjct: 658 ----AEPGQEQAEPPQE--------------------------------------CVECG 675

Query: 281 QSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHA 325
           +SF++S  L  H+  H  +  ++C  CGR F     L  H++ HA
Sbjct: 676 KSFSRSCNLLRHLLVHTGARPYSCTQCGRSFSRNSHLLRHLRTHA 720



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 23/67 (34%), Positives = 30/67 (44%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
           C  CG  FR + HL  HL  H+ E  + C  C     +  SL  HL  H ++Q+    P 
Sbjct: 351 CHLCGHRFRQSSHLSKHLLTHSSEPAFLCAECGRGFQRRASLVQHLLAHAQDQKPPCAPE 410

Query: 560 PPPEPPP 566
              E PP
Sbjct: 411 SKAEAPP 417



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 44/155 (28%), Positives = 61/155 (39%), Gaps = 15/155 (9%)

Query: 409 PLSSALPARARRHRAEEPEEEE-EVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAA 467
           P + A PA      +  P++EE +  E +   W       S A     PGE P   +   
Sbjct: 197 PENKAWPAHPLGFGSRTPDKEEFKQEEPKGAAWPTPILAESQADSPGVPGE-PCAQSLGR 255

Query: 468 GAQARSTATQEENGLLVGGTRPEGGRGATGKD---------CPFCGKSFRSAHHLKVH-L 517
           GA A       E+G L+G +     + A G           C  CG SF     LK H L
Sbjct: 256 GAAASGPG---EDGSLLGSSEILEVKVAEGVPEPNPELQFICADCGVSFPQLSRLKAHQL 312

Query: 518 RVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
           R H   R + C  C  +  +S  LK H++ H  E+
Sbjct: 313 RSHPAGRSFLCLCCGKSFGRSSILKLHMRTHTDER 347



 Score = 38.1 bits (87), Expect = 0.029
 Identities = 95/396 (23%), Positives = 135/396 (34%), Gaps = 88/396 (22%)

Query: 207 HSLTAHGAPERPLAATSAAPPPQPQPQ------------PPPQPEPRSVPQPEPEPEPER 254
           HS       E P     +  PP+PQP+            PP   +P S P P+   +  +
Sbjct: 106 HSPKKELPAEEPSVLGPSDEPPRPQPRAAQPAEPGQWRLPPSSKQPLS-PGPQKTFQALQ 164

Query: 255 EATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEP 314
           E++P      PEE     E    +   +F         + ++KA   H      R   + 
Sbjct: 165 ESSPQGPSPWPEESSRDQELAAVLECLTFED-------VPENKAWPAHPLGFGSRTPDKE 217

Query: 315 WFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERRE 374
            F +   K  A        P P    ++A  P   G    + LG     A A  P E   
Sbjct: 218 EFKQEEPKGAAW-------PTPILAESQADSPGVPGEPCAQSLGRG---AAASGPGE--- 264

Query: 375 PPSLLG---YLSLRAGEGRPNGEGAEPGPGRSF------GGFRPLSSALPARARRHRAEE 425
             SLLG    L ++  EG P     EP P   F        F  LS     + R H A  
Sbjct: 265 DGSLLGSSEILEVKVAEGVP-----EPNPELQFICADCGVSFPQLSRLKAHQLRSHPAGR 319

Query: 426 PEEEEEVVEAEEETWARGRSLG--SLASLHPRP--GEGPGHSASAAGAQARSTATQEENG 481
                            G+S G  S+  LH R    E P H+    G + R ++   ++ 
Sbjct: 320 ----------SFLCLCCGKSFGRSSILKLHMRTHTDERP-HACHLCGHRFRQSSHLSKH- 367

Query: 482 LLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERP---------------- 525
           LL   + P          C  CG+ F+    L  HL  H  ++                 
Sbjct: 368 LLTHSSEP-------AFLCAECGRGFQRRASLVQHLLAHAQDQKPPCAPESKAEAPPLTD 420

Query: 526 YKCPHCDYAGTQSGSLKYHLQRHHR--EQRSGAGPG 559
             C HC  +  +  SLK HL+ H R  ++RS  G G
Sbjct: 421 VLCSHCGQSFQRRSSLKRHLRIHARDKDRRSSEGSG 456


>gi|48717241 zinc finger protein 425 [Homo sapiens]
          Length = 752

 Score =  113 bits (283), Expect = 5e-25
 Identities = 126/505 (24%), Positives = 176/505 (34%), Gaps = 87/505 (17%)

Query: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP 112
           G+R +PCP C K FR+ + L  HL  H G + F C  CG    Q+  L  HLR H  E+P
Sbjct: 270 GQRPYPCPECDKTFRYRANLKKHLCLHRGERPFCCGECGRAFVQQCELTEHLRLHSGEKP 329

Query: 113 -RSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGK 171
            + P       L+                 GM+         RP       F CP C   
Sbjct: 330 FQCPQCDRCFRLKR----------------GMKVHLTQHSGKRP-------FHCPECGRS 366

Query: 172 FRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQ 229
           F   A  + H   H   +P+ CG C      + +L  H     G                
Sbjct: 367 FSRKAALKTHQRTHSEEKPFSCGECGRKFIYKIKLDEHIRVHTGE--------------- 411

Query: 230 PQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFL 289
                    +P S P+       +R           + P     F+C  C + F     +
Sbjct: 412 ---------KPFSCPECNKSFRLKRSLKAHGLQHIGKRP-----FQCPECSRGFFWRNAM 457

Query: 290 KGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVH-ASKLGPL-RAPGPASGPARAPQPP 347
           + H R H       C  CG+ F  P  L  H +VH   K  P        S  +R  Q  
Sbjct: 458 RAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCGECKKTFSQQSRLTQH- 516

Query: 348 DLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGF 407
              L  +    P    + A      R    L  +  L +GE        EP         
Sbjct: 517 ---LKVHTTEKP---FSCAECGRSFRRRAHLTEHTRLHSGE--------EPFQCPECDKS 562

Query: 408 RPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAA 467
               +++    R HR E+P    E     ++T+     L     LH   GE P +     
Sbjct: 563 FSWKASMKFHQRMHRDEKPFACGEC----DKTYTHQSQLTEHLRLHS--GEKP-YQCPEC 615

Query: 468 GAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYK 527
               R     + + L   G +P          C  CGKSF   + L  H+RVH+GE+P++
Sbjct: 616 EKTFRLKGNLKSHLLQHSGQKPFS--------CVMCGKSFTQQYRLTEHIRVHSGEKPFQ 667

Query: 528 CPHCDYAGTQSGSLKYHLQRHHREQ 552
           CP CD +    GSLK HL +H  E+
Sbjct: 668 CPECDKSYCIRGSLKVHLYKHSGER 692



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 70/291 (24%), Positives = 114/291 (39%), Gaps = 23/291 (7%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPER 111
           +GE+ F CP C + FR    + +HL  H G + F CP CG   +++A L++H RTH  E+
Sbjct: 325 SGEKPFQCPQCDRCFRLKRGMKVHLTQHSGKRPFHCPECGRSFSRKAALKTHQRTHSEEK 384

Query: 112 P-------RSPAARLLLELEERALLREARLG--RARSSGGMQATPATEGLARPQAPSSSA 162
           P       R    ++ L+   R    E          S  ++ +    GL   Q      
Sbjct: 385 PFSCGECGRKFIYKIKLDEHIRVHTGEKPFSCPECNKSFRLKRSLKAHGL---QHIGKRP 441

Query: 163 FRCPYCKGKF--RTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLA 220
           F+CP C   F  R +    + LH   +P+ C  C    ++  +L  H+       E P  
Sbjct: 442 FQCPECSRGFFWRNAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCG 501

Query: 221 ATSAAPPPQPQ----PQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRC 276
                   Q +     +     +P S  +           T      + EEP     F+C
Sbjct: 502 ECKKTFSQQSRLTQHLKVHTTEKPFSCAECGRSFRRRAHLTEHTRLHSGEEP-----FQC 556

Query: 277 QVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
             C +SF+    +K H R H+     AC  C + +     L  H+++H+ +
Sbjct: 557 PECDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGE 607



 Score = 87.0 bits (214), Expect = 5e-17
 Identities = 68/276 (24%), Positives = 102/276 (36%), Gaps = 53/276 (19%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
           E+ F C  CG+ FR  + L  H R H G + FQCP C    + +A ++ H R H+ E+P 
Sbjct: 523 EKPFSCAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFHQRMHRDEKPF 582

Query: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFR 173
           +          +  L    RL     SG                     ++CP C+  FR
Sbjct: 583 ACGECDKTYTHQSQLTEHLRL----HSG------------------EKPYQCPECEKTFR 620

Query: 174 TSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQ 231
                + HL  H   +P+ C +C    +Q+  L  H     G  E+P             
Sbjct: 621 LKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSG--EKPFQC---------- 668

Query: 232 PQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKG 291
               P+ +     +   +    + +   P             F+C  CG+ F Q   LK 
Sbjct: 669 ----PECDKSYCIRGSLKVHLYKHSGERP-------------FQCPECGKGFLQKRSLKA 711

Query: 292 HMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
           H+  H      +C  CGR F     LK H+ VHA +
Sbjct: 712 HLCLHSGERPFSCDECGRSFTYVGALKTHIAVHAKE 747



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 25/54 (46%), Positives = 37/54 (68%), Gaps = 1/54 (1%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQR 553
           C  CG+SFR   HL  H R+H+GE P++CP CD + +   S+K+H QR HR+++
Sbjct: 528 CAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKFH-QRMHRDEK 580



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 77/298 (25%), Positives = 109/298 (36%), Gaps = 36/298 (12%)

Query: 49  ESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQ 108
           E   G R + C VC K F+    L  H R+H  +Q   C +  ++ + R   +S LR  Q
Sbjct: 182 EIPTGPRCYSCYVCRKVFQVRRDLLKHKRSHSKSQL--CRYPKYKNSSRG--KSELRRTQ 237

Query: 109 PERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYC 168
                    RLL +       +  +      S  ++ +  T  +          + CP C
Sbjct: 238 ---------RLLCQK------KRFQCSECEKSYFLKGSLVTHQVVHT---GQRPYPCPEC 279

Query: 169 KGKFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAP 226
              FR  A  ++HL  H   RP+ CG C     Q+ EL  H L  H   E+P        
Sbjct: 280 DKTFRYRANLKKHLCLHRGERPFCCGECGRAFVQQCELTEH-LRLHSG-EKPFQCPQCDR 337

Query: 227 PPQPQPQPPPQPEPRSVPQPEPEPEPERE-----ATPTPAPAAPEEPPAPPEFRCQVCGQ 281
             + +          S  +P   PE  R      A  T      EE P    F C  CG+
Sbjct: 338 CFRLKRGMKVHLTQHSGKRPFHCPECGRSFSRKAALKTHQRTHSEEKP----FSCGECGR 393

Query: 282 SFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASG 339
            F     L  H+R H      +CP C + F+    LK H   H  K  P + P  + G
Sbjct: 394 KFIYKIKLDEHIRVHTGEKPFSCPECNKSFRLKRSLKAHGLQHIGK-RPFQCPECSRG 450



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 27/63 (42%), Positives = 35/63 (55%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPER 111
           +GE+ F CP C K +     L +HL  H G + FQCP CG    Q+  L++HL  H  ER
Sbjct: 661 SGEKPFQCPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSGER 720

Query: 112 PRS 114
           P S
Sbjct: 721 PFS 723



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 47/177 (26%), Positives = 66/177 (37%), Gaps = 10/177 (5%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPER 111
           +GE  F CP C K F + + +  H R H   + F C  C      ++ L  HLR H  E+
Sbjct: 549 SGEEPFQCPECDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEK 608

Query: 112 PR-----SPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPS-SSAFRC 165
           P          RL   L+   L    +   +    G   T         +  S    F+C
Sbjct: 609 PYQCPECEKTFRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKPFQC 668

Query: 166 PYCKGKFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLA 220
           P C   +      + HL  H   RP++C  C  G  Q+  L  H     G  ERP +
Sbjct: 669 PECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSG--ERPFS 723



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 48/170 (28%), Positives = 67/170 (39%), Gaps = 28/170 (16%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPER 111
           +GE+ + CP C K FR    L  HL  H G + F C  CG    Q+  L  H+R H  E+
Sbjct: 605 SGEKPYQCPECEKTFRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEK 664

Query: 112 P-RSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKG 170
           P + P      E ++   +R          G ++         RP       F+CP C  
Sbjct: 665 PFQCP------ECDKSYCIR----------GSLKVHLYKHSGERP-------FQCPECGK 701

Query: 171 KFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERP 218
            F      + H  LH   RP+ C  C    +    L  H +  H A E+P
Sbjct: 702 GFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTH-IAVH-AKEKP 749



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 25/55 (45%), Positives = 33/55 (60%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554
           CP CGK F     LK HL +H+GERP+ C  C  + T  G+LK H+  H +E+ S
Sbjct: 696 CPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTHIAVHAKEKPS 750



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 25/63 (39%), Positives = 31/63 (49%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPER 111
           +GER F CP CGK F     L  HL  H G + F C  CG        L++H+  H  E+
Sbjct: 689 SGERPFQCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTHIAVHAKEK 748

Query: 112 PRS 114
           P S
Sbjct: 749 PSS 751



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 26/53 (49%), Positives = 31/53 (58%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
           CP C KS+     LKVHL  H+GERP++CP C     Q  SLK HL  H  E+
Sbjct: 668 CPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSGER 720



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 22/58 (37%), Positives = 33/58 (56%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAG 557
           CP C + FR    +KVHL  H+G+RP+ CP C  + ++  +LK H + H  E+    G
Sbjct: 332 CPQCDRCFRLKRGMKVHLTQHSGKRPFHCPECGRSFSRKAALKTHQRTHSEEKPFSCG 389



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 27/71 (38%), Positives = 36/71 (50%), Gaps = 5/71 (7%)

Query: 493 RGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
           RG     C  CG++F     L  HLR+H+GE+P++CP CD        +K HL +H    
Sbjct: 297 RGERPFCCGECGRAFVQQCELTEHLRLHSGEKPFQCPQCDRCFRLKRGMKVHLTQH---- 352

Query: 553 RSGAGPGPPPE 563
            SG  P   PE
Sbjct: 353 -SGKRPFHCPE 362



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 23/54 (42%), Positives = 30/54 (55%), Gaps = 1/54 (1%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQR 553
           CP C KSFR    LK H   H G+RP++CP C        +++ H QR H EQ+
Sbjct: 416 CPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWRNAMRAH-QRLHSEQK 468



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 67/290 (23%), Positives = 103/290 (35%), Gaps = 68/290 (23%)

Query: 274 FRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRA 333
           + C  C ++F     LK H+  H+      C  CGR F +   L  H+++H+ +      
Sbjct: 274 YPCPECDKTFRYRANLKKHLCLHRGERPFCCGECGRAFVQQCELTEHLRLHSGEK----- 328

Query: 334 PGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAER--REPPSLLGYLSLRAGEGRP 391
                 P + PQ                         +R  R    +  +L+  +G+ RP
Sbjct: 329 ------PFQCPQ------------------------CDRCFRLKRGMKVHLTQHSGK-RP 357

Query: 392 NGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLAS 451
                 P  GRSF       +AL    R H  E+P    E           GR       
Sbjct: 358 FHC---PECGRSFSR----KAALKTHQRTHSEEKPFSCGEC----------GRKFIYKIK 400

Query: 452 L--HPR--PGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSF 507
           L  H R   GE P  S        R   + + +GL   G RP          CP C + F
Sbjct: 401 LDEHIRVHTGEKP-FSCPECNKSFRLKRSLKAHGLQHIGKRPF--------QCPECSRGF 451

Query: 508 RSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAG 557
              + ++ H R+H+ ++P+ C  C    T+   L  H + H R++    G
Sbjct: 452 FWRNAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCG 501



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 23/53 (43%), Positives = 27/53 (50%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
           C  C KS+     L  H  VHTG+RPY CP CD       +LK HL  H  E+
Sbjct: 248 CSECEKSYFLKGSLVTHQVVHTGQRPYPCPECDKTFRYRANLKKHLCLHRGER 300


>gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]
          Length = 496

 Score =  112 bits (281), Expect = 9e-25
 Identities = 139/529 (26%), Positives = 169/529 (31%), Gaps = 116/529 (21%)

Query: 57  FPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPA 116
           F C  CGK FR+ S L  H   H   +   CP CG        L +HLR+H  ERP    
Sbjct: 23  FHCSECGKSFRYRSDLRRHFARHTALKPHACPRCGKGFKHSFNLANHLRSHTGERP---- 78

Query: 117 ARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSA 176
                                                         +RC  C   FR S 
Sbjct: 79  ----------------------------------------------YRCSACPKGFRDST 92

Query: 177 ERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAH-GAPERPLAATSAAPPPQPQPQ 233
               H  +H   +P+ C +C    S    L  H    H G    PL         QP P 
Sbjct: 93  GLLHHQVVHTGEKPYCCLVCELRFSSRSSLGRHLKRQHRGVLPSPL---------QPGPG 143

Query: 234 PPPQPEPRSV----------------PQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQ 277
            P    P SV                    PE       +   A AA     + P F C 
Sbjct: 144 LPALSAPCSVCCNVGPCSVCGGSGAGGGEGPEGAGAGLGSWGLAEAAAAAAASLPPFACG 203

Query: 278 VCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGP- 336
            C + F     L  H   H       CP C R F  P  L+ H   H  + GP   P   
Sbjct: 204 ACARRFDHGRELAAHWAAHTDVKPFKCPRCERDFNAPALLERHKLTHDLQ-GPGAPPAQA 262

Query: 337 -ASGPARAPQPPDLGLLAYEPLGP-----ALLLAPAPTPAERREPPSLLGYLSLRAGEGR 390
            A+GP   P+    G  A     P      LLL PA         P L G L    GE  
Sbjct: 263 WAAGPGAGPETAGEGTAAEAGDAPLASDRRLLLGPAGGGV-----PKLGGLLPEGGGEAP 317

Query: 391 PNGEGAEPGPGRSF----GGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSL 446
                AEP     +    G F   ++AL +    H             A       G   
Sbjct: 318 APAAAAEPSEDTLYQCDCGTFFASAAALASHLEAHSG----------PATYGCGHCGALY 367

Query: 447 GSLASL--HPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEG-GRGATGKDCPFC 503
            +LA+L  H R   G G      G +  +TA +E       G  P G GRG     C  C
Sbjct: 368 AALAALEEHRRVSHGEG------GGEEAATAAREREP--ASGEPPSGSGRGKKIFGCSEC 419

Query: 504 GKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
            K FRS   L+ H+ VHTGE+P+ C  C         LK H   H  E+
Sbjct: 420 EKLFRSPRDLERHVLVHTGEKPFPCLECGKFFRHECYLKRHRLLHGTER 468



 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 113/425 (26%), Positives = 145/425 (34%), Gaps = 109/425 (25%)

Query: 243 VPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDH 302
           VP P P P P       PA AAP  P     F C  CG+SF     L+ H  +H A   H
Sbjct: 4   VPAPTPAPAP-------PAAAAPRVP-----FHCSECGKSFRYRSDLRRHFARHTALKPH 51

Query: 303 ACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASG-----------PARAPQPP---- 347
           ACP CG+ FK  + L NH++ H  +  P R      G                + P    
Sbjct: 52  ACPRCGKGFKHSFNLANHLRSHTGE-RPYRCSACPKGFRDSTGLLHHQVVHTGEKPYCCL 110

Query: 348 --DLGLLAYEPLGPALL----------LAPAPTPAERREPPSL---LGYLSLRAGEGRPN 392
             +L   +   LG  L           L P P       P S+   +G  S+  G G   
Sbjct: 111 VCELRFSSRSSLGRHLKRQHRGVLPSPLQPGPGLPALSAPCSVCCNVGPCSVCGGSGAGG 170

Query: 393 GEGAEPGPGRSFGGF------RPLSSALP-----ARARRH-------------------- 421
           GEG E G G   G +         +++LP     A ARR                     
Sbjct: 171 GEGPE-GAGAGLGSWGLAEAAAAAAASLPPFACGACARRFDHGRELAAHWAAHTDVKPFK 229

Query: 422 --RAEEPEEEEEVVEAEEETW-ARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQE 478
             R E       ++E  + T   +G       +    PG GP  +     A+A       
Sbjct: 230 CPRCERDFNAPALLERHKLTHDLQGPGAPPAQAWAAGPGAGPETAGEGTAAEAGDAPLAS 289

Query: 479 ENGLL----------VGGTRPEGGRGA------------TGKDCPFCGKSFRSAHHLKVH 516
           +  LL          +GG  PEGG  A            T   C  CG  F SA  L  H
Sbjct: 290 DRRLLLGPAGGGVPKLGGLLPEGGGEAPAPAAAAEPSEDTLYQCD-CGTFFASAAALASH 348

Query: 517 LRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQS 576
           L  H+G   Y C HC        +L+ H +  H E   G G     E    + R   P S
Sbjct: 349 LEAHSGPATYGCGHCGALYAALAALEEHRRVSHGE---GGG-----EEAATAAREREPAS 400

Query: 577 GAKPS 581
           G  PS
Sbjct: 401 GEPPS 405



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 86/328 (26%), Positives = 117/328 (35%), Gaps = 46/328 (14%)

Query: 32  GPAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCG 91
           G     GS G+   + + + A    F C  C +RF     LA H  AH   + F+CP C 
Sbjct: 176 GAGAGLGSWGLAEAA-AAAAASLPPFACGACARRFDHGRELAAHWAAHTDVKPFKCPRCE 234

Query: 92  HRAAQRALLRSHLRTHQPERPRSPAARLL-----------------------LELEERAL 128
                 ALL  H  TH  + P +P A+                         L  + R L
Sbjct: 235 RDFNAPALLERHKLTHDLQGPGAPPAQAWAAGPGAGPETAGEGTAAEAGDAPLASDRRLL 294

Query: 129 LREA-----RLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERERHLH 183
           L  A     +LG     GG +A PA    A P     + ++C  C   F ++A    HL 
Sbjct: 295 LGPAGGGVPKLGGLLPEGGGEA-PAPAAAAEPS--EDTLYQCD-CGTFFASAAALASHLE 350

Query: 184 ILHRP--WKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPR 241
               P  + CG C    +    L  H   +HG      AAT AA   +P    PP    R
Sbjct: 351 AHSGPATYGCGHCGALYAALAALEEHRRVSHGEGGGEEAAT-AAREREPASGEPPSGSGR 409

Query: 242 -----SVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296
                   + E      R+          E+P     F C  CG+ F    +LK H   H
Sbjct: 410 GKKIFGCSECEKLFRSPRDLERHVLVHTGEKP-----FPCLECGKFFRHECYLKRHRLLH 464

Query: 297 KASFDHACPVCGRCFKEPWFLKNHMKVH 324
                  C +CG+ F     L  H+K+H
Sbjct: 465 GTERPFPCHICGKGFITLSNLSRHLKLH 492



 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 84/333 (25%), Positives = 121/333 (36%), Gaps = 46/333 (13%)

Query: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHL-RTHQ 108
           S  GER + C  C K FR ++ L  H   H G + + C  C  R + R+ L  HL R H+
Sbjct: 72  SHTGERPYRCSACPKGFRDSTGLLHHQVVHTGEKPYCCLVCELRFSSRSSLGRHLKRQHR 131

Query: 109 PERPR-----------SPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQA 157
              P            S    +   +   ++   +  G      G  A   + GLA   A
Sbjct: 132 GVLPSPLQPGPGLPALSAPCSVCCNVGPCSVCGGSGAGGGEGPEGAGAGLGSWGLAEAAA 191

Query: 158 PSSSA---FRCPYCKGKFRTSAERERH--LHILHRPWKCGLC----SFGSSQEEELLHHS 208
            ++++   F C  C  +F    E   H   H   +P+KC  C    +  +  E   L H 
Sbjct: 192 AAAASLPPFACGACARRFDHGRELAAHWAAHTDVKPFKCPRCERDFNAPALLERHKLTHD 251

Query: 209 LTAHGAPERPLAATSAAPPPQPQP----------QPPPQPEPRSVPQPEPEPEPE----- 253
           L   GAP  P  A +A P   P+             P   + R +  P     P+     
Sbjct: 252 LQGPGAP--PAQAWAAGPGAGPETAGEGTAAEAGDAPLASDRRLLLGPAGGGVPKLGGLL 309

Query: 254 -REATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFK 312
                  PAPAA  EP     ++C  CG  F  +  L  H+  H     + C  CG  + 
Sbjct: 310 PEGGGEAPAPAAAAEPSEDTLYQCD-CGTFFASAAALASHLEAHSGPATYGCGHCGALYA 368

Query: 313 EPWFLKNHMKVHASKLG------PLRAPGPASG 339
               L+ H +V   + G        R   PASG
Sbjct: 369 ALAALEEHRRVSHGEGGGEEAATAAREREPASG 401



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 66/224 (29%), Positives = 83/224 (37%), Gaps = 42/224 (18%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYH--------------- 544
           CP CGK F+ + +L  HLR HTGERPY+C  C      S  L +H               
Sbjct: 53  CPRCGKGFKHSFNLANHLRSHTGERPYRCSACPKGFRDSTGLLHHQVVHTGEKPYCCLVC 112

Query: 545 ---------LQRHHREQRSGAGPGPPPEPPPPSQRGSAPQS-GAKPSPQPATWVEGASSP 594
                    L RH + Q  G  P  P +P P     SAP S      P       GA   
Sbjct: 113 ELRFSSRSSLGRHLKRQHRGVLPS-PLQPGPGLPALSAPCSVCCNVGPCSVCGGSGAGGG 171

Query: 595 R-PPSSGAGPGS---RRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALH---- 646
             P  +GAG GS       A+   +L     G       + R   G E     A H    
Sbjct: 172 EGPEGAGAGLGSWGLAEAAAAAAASLPPFACGAC-----ARRFDHGRELAAHWAAHTDVK 226

Query: 647 --RCLFCPFATGAPELMALHLQVHHSRRARGRRPPQADASPPYA 688
             +C  C     AP L+  H ++ H  +  G  P QA A+ P A
Sbjct: 227 PFKCPRCERDFNAPALLERH-KLTHDLQGPGAPPAQAWAAGPGA 269



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 70/278 (25%), Positives = 92/278 (33%), Gaps = 51/278 (18%)

Query: 457 GEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVH 516
           G G G     AGA   S    E          P          C  C + F     L  H
Sbjct: 167 GAGGGEGPEGAGAGLGSWGLAEAAAAAAASLPPFA--------CGACARRFDHGRELAAH 218

Query: 517 LRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQS 576
              HT  +P+KCP C+        L+ H   H  +     GPG PP     +  G+ P++
Sbjct: 219 WAAHTDVKPFKCPRCERDFNAPALLERHKLTHDLQ-----GPGAPPAQAWAAGPGAGPET 273

Query: 577 GAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPG 636
             + +   A     AS  R     AG G  +     G  L  G GGEA          P 
Sbjct: 274 AGEGTAAEAGDAPLASDRRLLLGPAGGGVPKL----GGLLPEG-GGEAP--------APA 320

Query: 637 GEAGPG-GALHRCLFCPFATGAPELMALHLQVH-----------------------HSRR 672
             A P    L++C    F   A  L A HL+ H                       H R 
Sbjct: 321 AAAEPSEDTLYQCDCGTFFASAAAL-ASHLEAHSGPATYGCGHCGALYAALAALEEHRRV 379

Query: 673 ARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLS 710
           + G    +  A+    R P+   PPS S  G++  G S
Sbjct: 380 SHGEGGGEEAATAAREREPASGEPPSGSGRGKKIFGCS 417



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 21/56 (37%), Positives = 26/56 (46%)

Query: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQ 108
           GE+ FPC  CGK FR    L  H   H   + F C  CG      + L  HL+ H+
Sbjct: 438 GEKPFPCLECGKFFRHECYLKRHRLLHGTERPFPCHICGKGFITLSNLSRHLKLHR 493



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 15/28 (53%), Positives = 18/28 (64%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPG 81
           ER FPC +CGK F   S L+ HL+ H G
Sbjct: 467 ERPFPCHICGKGFITLSNLSRHLKLHRG 494


>gi|154744870 zinc finger protein 574 [Homo sapiens]
          Length = 896

 Score =  110 bits (276), Expect = 4e-24
 Identities = 142/582 (24%), Positives = 199/582 (34%), Gaps = 151/582 (25%)

Query: 57  FPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRS-P 115
           F CP+C + F   S L  HL  H     F C  CG      ALL +H R H P    S P
Sbjct: 336 FKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCP 395

Query: 116 AARLLLELEERALLREARLGRARSSGGMQAT---------------PATEGLARPQAP-- 158
             +  + L +    R     R    GG+                  PA      P+AP  
Sbjct: 396 CGKTFVNLTKFLYHR-----RTHGVGGVPLPTTPVPPEEPVIGFPEPAPAETGEPEAPEP 450

Query: 159 -----------SSSAFRCPYCKGKFRTSAERERH---LHILHRPWKCGLCSFGSSQEEEL 204
                      +   +RC  C  +F  + +  RH   +H L R  KC +C     ++  +
Sbjct: 451 PVSEETSAGPAAPGTYRCLLCSREFGKALQLTRHQRFVHRLERRHKCSICGKMFKKKSHV 510

Query: 205 LHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAA 264
            +H  T  G  ERP                 P P+  S P   P        T T     
Sbjct: 511 RNHLRTHTG--ERPF----------------PCPDC-SKPFNSPANLARHRLTHTG---- 547

Query: 265 PEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNH---- 320
            E P     +RC  CG++FTQS  L+ H   H   F + C  CG  F  P+ L  H    
Sbjct: 548 -ERP-----YRCGDCGKAFTQSSTLRQHRLVHAQHFPYRCQECGVRFHRPYRLLMHRYHH 601

Query: 321 -------------------------MKVHASKLGPLRAPGP---------------ASGP 340
                                    + VHA +  P R P                 A+  
Sbjct: 602 TGEYPYKCRECPRSFLLRRLLEVHQLVVHAGRQ-PHRCPSCGAAFPSSLRLREHRCAAAA 660

Query: 341 ARAPQPPDLGLLAYEPLGPALLL--------APAPTPAERREPPSLLGYLSLRAGEGRPN 392
           A+AP+  + G    + +G A  L        A  P     +EPP+             P 
Sbjct: 661 AQAPRRFECGTCG-KKVGSAARLQAHEAAHAAAGPGEVLAKEPPA-------------PR 706

Query: 393 GEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASL 452
              A   P  S       ++A PA   R R  E  E +++   E       R       +
Sbjct: 707 APRATRAPVASPAALGSTATASPAAPARRRGLECSECKKLFSTETSLQVHRR-------I 759

Query: 453 HPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHH 512
           H   GE P +     G   R +   +++  L  G RP          C  CGK+F  +  
Sbjct: 760 HT--GERP-YPCPDCGKAFRQSTHLKDHRRLHTGERPFA--------CEVCGKAFAISMR 808

Query: 513 LKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554
           L  H R+HTGERPY CP C  +     +L  H + H ++ ++
Sbjct: 809 LAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQA 850



 Score = 96.7 bits (239), Expect = 7e-20
 Identities = 82/305 (26%), Positives = 115/305 (37%), Gaps = 36/305 (11%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
           ERR  C +CGK F+  S +  HLR H G + F CP C       A L  H  TH  ERP 
Sbjct: 492 ERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTHTGERPY 551

Query: 114 SPAARLLLELEERALLREARL-------GRARSSGGMQATPATEGLARPQAPSSSAFRCP 166
                      + + LR+ RL        R +  G     P    + R        ++C 
Sbjct: 552 R-CGDCGKAFTQSSTLRQHRLVHAQHFPYRCQECGVRFHRPYRLLMHRYHHTGEYPYKCR 610

Query: 167 YCKGKFRTSAERERHLHILH---RPWKCGLCSFGSSQEEELLHH--SLTAHGAPER---- 217
            C   F      E H  ++H   +P +C  C         L  H  +  A  AP R    
Sbjct: 611 ECPRSFLLRRLLEVHQLVVHAGRQPHRCPSCGAAFPSSLRLREHRCAAAAAQAPRRFECG 670

Query: 218 --------------PLAATSAAPPPQPQPQPPPQPE-PRSVPQPEPEPEPEREATPTPAP 262
                           AA +AA P +   + PP P  PR+   P   P     A  + A 
Sbjct: 671 TCGKKVGSAARLQAHEAAHAAAGPGEVLAKEPPAPRAPRATRAPVASP----AALGSTAT 726

Query: 263 AAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMK 322
           A+P  P       C  C + F+    L+ H R H     + CP CG+ F++   LK+H +
Sbjct: 727 ASPAAPARRRGLECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRR 786

Query: 323 VHASK 327
           +H  +
Sbjct: 787 LHTGE 791



 Score = 87.4 bits (215), Expect = 4e-17
 Identities = 134/556 (24%), Positives = 186/556 (33%), Gaps = 94/556 (16%)

Query: 33  PAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILA----LHLR---------AH 79
           P V+  +         ++   E ++ C  CG+     S L     LHL+         A 
Sbjct: 52  PGVTVATDTASGTGLYQTLVQESQYQCLECGQLLMSPSQLLEHQELHLKMMAPQEAVPAE 111

Query: 80  PGAQA---------FQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLR 130
           P  +A         ++C  C    A + L  +H +TH    P    A ++L      ++ 
Sbjct: 112 PSPKAPPLSSSTIHYECVDCKALFASQELWLNHRQTHLRATPTKAPAPVVL---GSPVVL 168

Query: 131 EARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERERHLHILHRPWK 190
              +G+AR +       A EG      PS++A           T+ E    + +L   +K
Sbjct: 169 GPPVGQARVAVEHSYRKAEEGGEGATVPSAAA-----------TTTEVVTEVELL--LYK 215

Query: 191 CGLCSFGSSQEEELLHHSLTAHGAP---------ERPLAATSAAPPPQPQPQP-PPQPEP 240
           C  CS       + L H  T   AP         ++ + A+S A  P  QP P P     
Sbjct: 216 CSECSQLFQLPADFLEHQATHFPAPVPESQEPALQQEVQASSPAEVPVSQPDPLPASDHS 275

Query: 241 RSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASF 300
             +   E      R        +      A  E  C  C Q F     L+ H+R H+   
Sbjct: 276 YELRNGEAIGRDRRGRRARRNNSGEAGGAATQELFCSACDQLFLSPHQLQQHLRSHREGV 335

Query: 301 DHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGL-LAYEPLGP 359
              CP+C R F  P  L  H+  H+S+   L                D GL    E L  
Sbjct: 336 -FKCPLCSRVFPSPSSLDQHLGDHSSESHFLCV--------------DCGLAFGTEALLL 380

Query: 360 ALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRP-LSSALPARA 418
           A   A  P P            L+      R +G G  P P        P +    PA A
Sbjct: 381 AHRRAHTPNPLHSCPCGKTFVNLTKFLYHRRTHGVGGVPLPTTPVPPEEPVIGFPEPAPA 440

Query: 419 RRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQE 478
                E PE         EET A                 GP     AA    R      
Sbjct: 441 ETGEPEAPEP-----PVSEETSA-----------------GP-----AAPGTYRCLLCSR 473

Query: 479 ENGLLVGGTRPEG--GRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGT 536
           E G  +  TR +    R      C  CGK F+   H++ HLR HTGERP+ CP C     
Sbjct: 474 EFGKALQLTRHQRFVHRLERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFN 533

Query: 537 QSGSLKYHLQRHHREQ 552
              +L  H   H  E+
Sbjct: 534 SPANLARHRLTHTGER 549



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 82/321 (25%), Positives = 112/321 (34%), Gaps = 74/321 (23%)

Query: 15  PSP-PAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAG---ERRFPCPVCGKRFRFNS 70
           P P PA D   +L+   NG A+     G  A   +   AG    +   C  C + F    
Sbjct: 266 PDPLPASDHSYELR---NGEAIGRDRRGRRARRNNSGEAGGAATQELFCSACDQLFLSPH 322

Query: 71  ILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLR 130
            L  HLR+H     F+CP C       + L  HL  H                       
Sbjct: 323 QLQQHLRSHREG-VFKCPLCSRVFPSPSSLDQHLGDHS---------------------- 359

Query: 131 EARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERERHLHILHRPWK 190
                                       S S F C  C   F T A    H    H P  
Sbjct: 360 ----------------------------SESHFLCVDCGLAFGTEALLLAHRRA-HTPNP 390

Query: 191 CGLCSFGSS--QEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPE- 247
              C  G +     + L+H  T HG    PL  T    PP+      P+P P    +PE 
Sbjct: 391 LHSCPCGKTFVNLTKFLYHRRT-HGVGGVPLPTTPV--PPEEPVIGFPEPAPAETGEPEA 447

Query: 248 PEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMR-KHKASFDHACPV 306
           PEP    E +  PA        AP  +RC +C + F ++  L  H R  H+    H C +
Sbjct: 448 PEPPVSEETSAGPA--------APGTYRCLLCSREFGKALQLTRHQRFVHRLERRHKCSI 499

Query: 307 CGRCFKEPWFLKNHMKVHASK 327
           CG+ FK+   ++NH++ H  +
Sbjct: 500 CGKMFKKKSHVRNHLRTHTGE 520



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 35/104 (33%), Positives = 44/104 (42%), Gaps = 4/104 (3%)

Query: 9   PSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRF 68
           P   LA  PPA        R +  P  S  +LG  A +   + A  R   C  C K F  
Sbjct: 694 PGEVLAKEPPAPRAP----RATRAPVASPAALGSTATASPAAPARRRGLECSECKKLFST 749

Query: 69  NSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP 112
            + L +H R H G + + CP CG    Q   L+ H R H  ERP
Sbjct: 750 ETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERP 793



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 29/62 (46%), Positives = 33/62 (53%)

Query: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP 112
           GER +PCP CGK FR ++ L  H R H G + F C  CG   A    L  H R H  ERP
Sbjct: 762 GERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGERP 821

Query: 113 RS 114
            S
Sbjct: 822 YS 823



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 8/100 (8%)

Query: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP 112
           GER F C VCGK F  +  LA H R H G + + CP CG      + L  H +THQ +  
Sbjct: 790 GERPFACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQ 849

Query: 113 RSPAARLLLELEERALLREARLGRARSSGGMQATPATEGL 152
            +        + ++    EA +G A     ++A P  E +
Sbjct: 850 AA--------VRQQLAEAEAAVGLAVMETAVEALPLVEAI 881



 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 107/466 (22%), Positives = 150/466 (32%), Gaps = 79/466 (16%)

Query: 274 FRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRA 333
           F C  CG +F     L  H R H  +  H+CP CG+ F        H + H     PL  
Sbjct: 364 FLCVDCGLAFGTEALLLAHRRAHTPNPLHSCP-CGKTFVNLTKFLYHRRTHGVGGVPLPT 422

Query: 334 PGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNG 393
                     P PP+  ++ +          P P PAE  EP +    +S     G    
Sbjct: 423 ---------TPVPPEEPVIGF----------PEPAPAETGEPEAPEPPVSEETSAGP--- 460

Query: 394 EGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLH 453
             A PG  R     R    AL     +      E   +     +    +      L +  
Sbjct: 461 --AAPGTYRCLLCSREFGKALQLTRHQRFVHRLERRHKCSICGKMFKKKSHVRNHLRT-- 516

Query: 454 PRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRP----EGGRGATGKD---------- 499
              GE P            S A    + L   G RP    + G+  T             
Sbjct: 517 -HTGERP-FPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRLVHA 574

Query: 500 ------CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQR 553
                 C  CG  F   + L +H   HTGE PYKC  C     +S  L+  L+ H     
Sbjct: 575 QHFPYRCQECGVRFHRPYRLLMHRYHHTGEYPYKCREC----PRSFLLRRLLEVHQLVVH 630

Query: 554 SGAGPGPPPE---PPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPS-----------S 599
           +G  P   P      P S R    +  A  +  P  +  G    +  S           +
Sbjct: 631 AGRQPHRCPSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHA 690

Query: 600 GAGPGS--RRKPASPGRTLRNGRGGEAEP--LDLSLRAGPGGEAGPGGALHRCLFCPFAT 655
            AGPG    ++P +P R  R  R   A P  L  +  A P   A   G    C  C    
Sbjct: 691 AAGPGEVLAKEPPAP-RAPRATRAPVASPAALGSTATASPAAPARRRGL--ECSECKKLF 747

Query: 656 GAPELMALHLQVHHSRRAR-----GRRPPQADASPPYARVPSGETP 696
                + +H ++H   R       G+   Q+     + R+ +GE P
Sbjct: 748 STETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERP 793



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 52/193 (26%), Positives = 71/193 (36%), Gaps = 28/193 (14%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQA---FQCPHCGHRAAQRALLRSHLRTH- 107
           AG +   CP CG  F  +  L  H  A   AQA   F+C  CG +    A L++H   H 
Sbjct: 631 AGRQPHRCPSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHA 690

Query: 108 ----------QPERPRSPAARLLLELEERALLREARLGRARSSG--GMQ--------ATP 147
                     +P  PR+P A         AL   A    A  +   G++        +T 
Sbjct: 691 AAGPGEVLAKEPPAPRAPRATRAPVASPAALGSTATASPAAPARRRGLECSECKKLFSTE 750

Query: 148 ATEGLARPQAPSSSAFRCPYCKGKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELL 205
            +  + R        + CP C   FR S   + H  LH   RP+ C +C    +    L 
Sbjct: 751 TSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLA 810

Query: 206 HHSLTAHGAPERP 218
            H     G  ERP
Sbjct: 811 EHRRIHTG--ERP 821



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 54/211 (25%), Positives = 67/211 (31%), Gaps = 39/211 (18%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH----------- 548
           CP C + F S   L  HL  H+ E  + C  C  A      L  H + H           
Sbjct: 338 CPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCPCG 397

Query: 549 -----------HREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPP 597
                      HR      G   P  P PP +    P  G  P P PA   E   +P PP
Sbjct: 398 KTFVNLTKFLYHRRTHGVGGVPLPTTPVPPEE----PVIGF-PEPAPAETGE-PEAPEPP 451

Query: 598 SSGAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGA 657
            S         P +    L +   G+A  L    R     E       H+C  C      
Sbjct: 452 VSEETSAGPAAPGTYRCLLCSREFGKALQLTRHQRFVHRLE-----RRHKCSICGKMFKK 506

Query: 658 PELMALHLQVHHSRRARGRRP-PQADASPPY 687
              +  HL+ H      G RP P  D S P+
Sbjct: 507 KSHVRNHLRTH-----TGERPFPCPDCSKPF 532



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 15/43 (34%), Positives = 20/43 (46%)

Query: 37  AGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAH 79
           A ++ M          GER + CP CGK +R  S L  H + H
Sbjct: 802 AFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTH 844


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score =  107 bits (266), Expect = 5e-23
 Identities = 123/474 (25%), Positives = 165/474 (34%), Gaps = 88/474 (18%)

Query: 163 FRCPYCKGKFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSL-------TAHG 213
           F C  C+  F+ S+   +H+  H   RP++CG+C    +    L+ H          A G
Sbjct: 224 FPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGG 283

Query: 214 APE-----------RPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAP 262
            P+            P A+ + A  P      PP       P  +    P     P PA 
Sbjct: 284 PPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPAT 343

Query: 263 AAPEEPPAPP-----------------------EFRCQVCGQSFTQSWFLKGHMRKHKAS 299
              + P A P                        F C VC +SF +   LK H++ H A 
Sbjct: 344 GGGDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSAD 403

Query: 300 FDHA-CPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLG 358
                C +CG+ F++  +L  H   HA         G  +G  R   P DL   +Y    
Sbjct: 404 LLRLPCGICGKAFRDASYLLKHQAAHA---------GAGAGGPRPVYPCDLCGKSYS--A 452

Query: 359 PALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARA 418
           P  LL      A    PP+        A E   +G  + P P  +F    P    LP   
Sbjct: 453 PQSLLRHKAAHA----PPAA-------AAEAPKDGAASAPQPPPTFP---PGPYLLPP-- 496

Query: 419 RRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQE 478
                + P  + E   A       G     L   HP    G G S  A G+ A       
Sbjct: 497 -----DPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSG-AGGSGASVPGKTF 550

Query: 479 ENGLLVGG-----TRPEGGRGATGK---DCPFCGKSFRSAHHLKVHLRVHTGERPYKCPH 530
             G+   G     T     R  TG+    CP CGK FR + HL  H  VHT ERPYKC  
Sbjct: 551 CCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCEL 610

Query: 531 CDYAGTQSGSLKYHLQRHHRE---QRSGAGPGPPPEPPPPSQRGSAPQSGAKPS 581
           C        SL  H Q H  +     +GA   P  +  P +    A  + A P+
Sbjct: 611 CGKVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTSAGPT 664



 Score =  106 bits (265), Expect = 7e-23
 Identities = 153/650 (23%), Positives = 217/650 (33%), Gaps = 174/650 (26%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
           ERRFPC VC K F+ +S L  H+  H G + ++C  CG      + L  H R H+   P 
Sbjct: 221 ERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPA 280

Query: 114 S-----PAARL-LLELEERALLREARLGRARSSGGMQAT-----PATEGLARPQA----- 157
           +     P   L  L L   A         +  S G  AT     P+ +G A P       
Sbjct: 281 AGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPP 340

Query: 158 PSSSA----FRCPYCKGKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLT- 210
           P++      F CP C   F+  +   +H  +H   +P+ C +CS   ++ E L  H  T 
Sbjct: 341 PATGGGDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTH 400

Query: 211 ------------------------------------------------AHGAPERPLAAT 222
                                                           ++ AP+  L   
Sbjct: 401 SADLLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHK 460

Query: 223 SAAPPP-------------QPQPQPPPQPEPRSVPQPEPEPEPEREAT--------PTPA 261
           +A  PP              PQP P   P P  +P   P  + E+ A           P 
Sbjct: 461 AAHAPPAAAAEAPKDGAASAPQPPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVYGAVPV 520

Query: 262 PAAPEEP----------------PAPPE-FRCQVCGQSFTQSWFLKGHMRKHKASFDHAC 304
           P     P                  P + F C +CG+ F +   LK H R H     H C
Sbjct: 521 PLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGICGRGFGRRETLKRHERIHTGEKPHQC 580

Query: 305 PVCGRCFKEPWFLKNHMKVHASKLGPLRAP--GPASGPARAPQPPDLGLLAYEPLGPALL 362
           PVCG+ F+E + L  H  VH ++  P +    G   G    PQ        +    P  L
Sbjct: 581 PVCGKRFRESFHLSKHHVVH-TRERPYKCELCGKVFG---YPQSLTRHRQVHRLQLPCAL 636

Query: 363 LAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSF-----GGFRPLSSALPAR 417
              A  P+ +  P +         G G  +G  A P  G S+     G   P    + + 
Sbjct: 637 AGAAGLPSTQGTPGA--------CGPG-ASGTSAGPTDGLSYACSDCGEHFPDLFHVMSH 687

Query: 418 ARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASL------HPRPGE-----GPGHSASA 466
              H AE+P   +          A G++ G + +L      H    E      PG     
Sbjct: 688 KEVHMAEKPYGCD----------ACGKTFGFIENLMWHKLVHQAAPERLLPPAPGGLQPP 737

Query: 467 AGAQARSTATQEENGLL------------VGGTRPEGGRGATGK-----------DCPFC 503
            G+     A+  +NGL             V G    GG    G             C  C
Sbjct: 738 DGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGGGASSGPERFSCATC 797

Query: 504 GKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQR 553
           G+SF+    L  H  VH   R   C  C  +   +  L  H +R HR++R
Sbjct: 798 GQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLH-RRSHRQKR 846



 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 147/584 (25%), Positives = 204/584 (34%), Gaps = 145/584 (24%)

Query: 203 ELLHHS----LTAHGAPERPLAATSAAP--PPQPQPQPPPQPEPRSVPQPEPEPEPEREA 256
           E L+H     +  +G   + +AA   AP  PPQP PQPPP P+    PQ   +P+ E  +
Sbjct: 35  EFLNHQRFEPMELYGEHAKAVAALPCAPGPPPQPPPQPPP-PQYDYPPQSTFKPKAEVPS 93

Query: 257 TPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWF 316
           + + + ++     +           S + S   K       A      P+    F  P +
Sbjct: 94  SSSSSSSSSSSSSSSSS------SSSSSSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQW 147

Query: 317 LKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPP 376
               +  H    G L+  GPASGP   P     GL A  P G     AP P PA  + PP
Sbjct: 148 GIVDLSGHQHLFGNLKRGGPASGPGVTP-----GLGA--PAG-----APGPLPAPSQTPP 195

Query: 377 SLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPAR------ARRHRAEEPEEEE 430
                       G P     +P      G FR L   +  R       +  +      + 
Sbjct: 196 ------------GPPAAAACDPTKDDK-GYFRRLKYLMERRFPCGVCQKSFKQSSHLVQH 242

Query: 431 EVVEAEE---ETWARGRSLGSLASL----------------HPRPGEG------PGHSAS 465
            +V + E   E    GR+   ++SL                 P+PG        P  +AS
Sbjct: 243 MLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPPQPGPHLPPLGLPAPAAS 302

Query: 466 AAGAQARSTATQEENGLLV-------GGTRPEG--------GRGATGKDCPFCGKSFRSA 510
           AA A A ST +       V       G   P G        G G     CP C K F+  
Sbjct: 303 AATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFACPLCWKVFKKP 362

Query: 511 HHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH---------------------- 548
            HL  H  +HTGE+P+ C  C  +  +  SLK H++ H                      
Sbjct: 363 SHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLRLPCGICGKAFRDASYL 422

Query: 549 --HREQRSGAGP-GPPPEPP----------------------PPSQRGSAPQSGAKPSPQ 583
             H+   +GAG  GP P  P                      PP+    AP+ GA  +PQ
Sbjct: 423 LKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKDGAASAPQ 482

Query: 584 -PATWVEG--ASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAG 640
            P T+  G     P PP++ +   +    A     +     G A PL L   AG  G  G
Sbjct: 483 PPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLG-AHPLLLG-GAGTSGAGG 540

Query: 641 PG----GALHRCLFCPFATGAPELMALHLQVHHSRRARGRRPPQ 680
            G    G    C  C    G  E +  H ++H      G +P Q
Sbjct: 541 SGASVPGKTFCCGICGRGFGRRETLKRHERIH-----TGEKPHQ 579



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 81/324 (25%), Positives = 109/324 (33%), Gaps = 39/324 (12%)

Query: 38  GSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQR 97
           G  G      S +    + F C +CG+ F     L  H R H G +  QCP CG R  + 
Sbjct: 531 GGAGTSGAGGSGASVPGKTFCCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRES 590

Query: 98  ALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRAR------SSGGMQATPATEG 151
             L  H   H  ERP        +    ++L R  ++ R +       + G+ +T  T G
Sbjct: 591 FHLSKHHVVHTRERPYKCELCGKVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPG 650

Query: 152 LARPQAPSSSA-------FRCPYCKGKFRT--SAERERHLHILHRPWKCGLCSFGSSQEE 202
              P A  +SA       + C  C   F         + +H+  +P+ C  C       E
Sbjct: 651 ACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIE 710

Query: 203 ELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP-----------------RSVPQ 245
            L+ H L    APER L       PP P    PP                      +V  
Sbjct: 711 NLMWHKLVHQAAPERLL-------PPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAA 763

Query: 246 PEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACP 305
                  E       A A       P  F C  CGQSF     L  H   H       C 
Sbjct: 764 LAGVSGGEDAGGAAVAGAGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCG 823

Query: 306 VCGRCFKEPWFLKNHMKVHASKLG 329
           +CG+ F   + L  H + H  K G
Sbjct: 824 LCGQSFAGAYDLLLHRRSHRQKRG 847



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 74/313 (23%), Positives = 102/313 (32%), Gaps = 80/313 (25%)

Query: 42   MGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLR 101
            +G V+        R   C +CG+ F     L LH R+H   + F+CP CG R  + ALL 
Sbjct: 805  LGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLM 864

Query: 102  SHLRTHQPERP-----------RSPAAR--LLLELEERALLREARLGRARSSGGMQATPA 148
             H R H  +RP           RS   R   ++   ERA        R   S  +     
Sbjct: 865  RHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRR 924

Query: 149  TEGLARPQAPSSSAFRCPYCKGKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLH 206
               +ARPQ       RC  C   FR  +    H  LH+  R ++C  C  G      +L 
Sbjct: 925  LHAVARPQ-------RCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLR 977

Query: 207  HSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPE 266
            H                       +   PP+ E R                         
Sbjct: 978  HQ----------------------RAHEPPRAELR------------------------- 990

Query: 267  EPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS 326
                     C  C ++F    + + H+  H+      C  CG  F   + LK H   H  
Sbjct: 991  ---------CPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAH-- 1039

Query: 327  KLGPLRAPGPASG 339
            K   L  PG  +G
Sbjct: 1040 KAENLGGPGAGAG 1052



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 21/60 (35%), Positives = 28/60 (46%)

Query: 500  CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
            CP C K+F+   + + HL  H G RP++C  C      +  LK H   H  E   G G G
Sbjct: 991  CPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAENLGGPGAG 1050



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 1/55 (1%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554
           C  CGK+FR   +L  H R+H GER Y+C HC        S+  H QR H   R+
Sbjct: 934 CSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRH-QRAHEPPRA 987



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 25/59 (42%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH--HREQRSGA 556
           C  CG+ F  + +L+ H  VHTGER +KC  C     QS SL  H + H   R QR  A
Sbjct: 878 CGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSA 936



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 25/65 (38%), Positives = 30/65 (46%)

Query: 493 RGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
           R   G  CP CGK F  A  L  H R HT +RPY+C  C     +S  L+ H   H  E+
Sbjct: 843 RQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGER 902

Query: 553 RSGAG 557
               G
Sbjct: 903 AFKCG 907



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 1/55 (1%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554
           C  C K F  +  L  H R+H   RP +C  C        +L  H QR H  +R+
Sbjct: 906 CGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEH-QRLHLGERA 959


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score =  107 bits (266), Expect = 5e-23
 Identities = 123/474 (25%), Positives = 165/474 (34%), Gaps = 88/474 (18%)

Query: 163 FRCPYCKGKFRTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSL-------TAHG 213
           F C  C+  F+ S+   +H+  H   RP++CG+C    +    L+ H          A G
Sbjct: 224 FPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGG 283

Query: 214 APE-----------RPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAP 262
            P+            P A+ + A  P      PP       P  +    P     P PA 
Sbjct: 284 PPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPAT 343

Query: 263 AAPEEPPAPP-----------------------EFRCQVCGQSFTQSWFLKGHMRKHKAS 299
              + P A P                        F C VC +SF +   LK H++ H A 
Sbjct: 344 GGGDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSAD 403

Query: 300 FDHA-CPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLG 358
                C +CG+ F++  +L  H   HA         G  +G  R   P DL   +Y    
Sbjct: 404 LLRLPCGICGKAFRDASYLLKHQAAHA---------GAGAGGPRPVYPCDLCGKSYS--A 452

Query: 359 PALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARA 418
           P  LL      A    PP+        A E   +G  + P P  +F    P    LP   
Sbjct: 453 PQSLLRHKAAHA----PPAA-------AAEAPKDGAASAPQPPPTFP---PGPYLLPP-- 496

Query: 419 RRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQE 478
                + P  + E   A       G     L   HP    G G S  A G+ A       
Sbjct: 497 -----DPPTTDSEKAAAAAAAVVYGAVPVPLLGAHPLLLGGAGTSG-AGGSGASVPGKTF 550

Query: 479 ENGLLVGG-----TRPEGGRGATGK---DCPFCGKSFRSAHHLKVHLRVHTGERPYKCPH 530
             G+   G     T     R  TG+    CP CGK FR + HL  H  VHT ERPYKC  
Sbjct: 551 CCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRESFHLSKHHVVHTRERPYKCEL 610

Query: 531 CDYAGTQSGSLKYHLQRHHRE---QRSGAGPGPPPEPPPPSQRGSAPQSGAKPS 581
           C        SL  H Q H  +     +GA   P  +  P +    A  + A P+
Sbjct: 611 CGKVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTSAGPT 664



 Score =  106 bits (265), Expect = 7e-23
 Identities = 153/650 (23%), Positives = 217/650 (33%), Gaps = 174/650 (26%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
           ERRFPC VC K F+ +S L  H+  H G + ++C  CG      + L  H R H+   P 
Sbjct: 221 ERRFPCGVCQKSFKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPA 280

Query: 114 S-----PAARL-LLELEERALLREARLGRARSSGGMQAT-----PATEGLARPQA----- 157
           +     P   L  L L   A         +  S G  AT     P+ +G A P       
Sbjct: 281 AGGPPQPGPHLPPLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPP 340

Query: 158 PSSSA----FRCPYCKGKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLT- 210
           P++      F CP C   F+  +   +H  +H   +P+ C +CS   ++ E L  H  T 
Sbjct: 341 PATGGGDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTH 400

Query: 211 ------------------------------------------------AHGAPERPLAAT 222
                                                           ++ AP+  L   
Sbjct: 401 SADLLRLPCGICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHK 460

Query: 223 SAAPPP-------------QPQPQPPPQPEPRSVPQPEPEPEPEREAT--------PTPA 261
           +A  PP              PQP P   P P  +P   P  + E+ A           P 
Sbjct: 461 AAHAPPAAAAEAPKDGAASAPQPPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVYGAVPV 520

Query: 262 PAAPEEP----------------PAPPE-FRCQVCGQSFTQSWFLKGHMRKHKASFDHAC 304
           P     P                  P + F C +CG+ F +   LK H R H     H C
Sbjct: 521 PLLGAHPLLLGGAGTSGAGGSGASVPGKTFCCGICGRGFGRRETLKRHERIHTGEKPHQC 580

Query: 305 PVCGRCFKEPWFLKNHMKVHASKLGPLRAP--GPASGPARAPQPPDLGLLAYEPLGPALL 362
           PVCG+ F+E + L  H  VH ++  P +    G   G    PQ        +    P  L
Sbjct: 581 PVCGKRFRESFHLSKHHVVH-TRERPYKCELCGKVFG---YPQSLTRHRQVHRLQLPCAL 636

Query: 363 LAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSF-----GGFRPLSSALPAR 417
              A  P+ +  P +         G G  +G  A P  G S+     G   P    + + 
Sbjct: 637 AGAAGLPSTQGTPGA--------CGPG-ASGTSAGPTDGLSYACSDCGEHFPDLFHVMSH 687

Query: 418 ARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASL------HPRPGE-----GPGHSASA 466
              H AE+P   +          A G++ G + +L      H    E      PG     
Sbjct: 688 KEVHMAEKPYGCD----------ACGKTFGFIENLMWHKLVHQAAPERLLPPAPGGLQPP 737

Query: 467 AGAQARSTATQEENGLL------------VGGTRPEGGRGATGK-----------DCPFC 503
            G+     A+  +NGL             V G    GG    G             C  C
Sbjct: 738 DGSSGTDAASVLDNGLAGEVGAAVAALAGVSGGEDAGGAAVAGAGGGASSGPERFSCATC 797

Query: 504 GKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQR 553
           G+SF+    L  H  VH   R   C  C  +   +  L  H +R HR++R
Sbjct: 798 GQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLH-RRSHRQKR 846



 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 147/584 (25%), Positives = 204/584 (34%), Gaps = 145/584 (24%)

Query: 203 ELLHHS----LTAHGAPERPLAATSAAP--PPQPQPQPPPQPEPRSVPQPEPEPEPEREA 256
           E L+H     +  +G   + +AA   AP  PPQP PQPPP P+    PQ   +P+ E  +
Sbjct: 35  EFLNHQRFEPMELYGEHAKAVAALPCAPGPPPQPPPQPPP-PQYDYPPQSTFKPKAEVPS 93

Query: 257 TPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWF 316
           + + + ++     +           S + S   K       A      P+    F  P +
Sbjct: 94  SSSSSSSSSSSSSSSSS------SSSSSSSQAKKPDPPLPPAFGAPPPPLFDAAFPTPQW 147

Query: 317 LKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPP 376
               +  H    G L+  GPASGP   P     GL A  P G     AP P PA  + PP
Sbjct: 148 GIVDLSGHQHLFGNLKRGGPASGPGVTP-----GLGA--PAG-----APGPLPAPSQTPP 195

Query: 377 SLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPAR------ARRHRAEEPEEEE 430
                       G P     +P      G FR L   +  R       +  +      + 
Sbjct: 196 ------------GPPAAAACDPTKDDK-GYFRRLKYLMERRFPCGVCQKSFKQSSHLVQH 242

Query: 431 EVVEAEE---ETWARGRSLGSLASL----------------HPRPGEG------PGHSAS 465
            +V + E   E    GR+   ++SL                 P+PG        P  +AS
Sbjct: 243 MLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPPQPGPHLPPLGLPAPAAS 302

Query: 466 AAGAQARSTATQEENGLLV-------GGTRPEG--------GRGATGKDCPFCGKSFRSA 510
           AA A A ST +       V       G   P G        G G     CP C K F+  
Sbjct: 303 AATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFACPLCWKVFKKP 362

Query: 511 HHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH---------------------- 548
            HL  H  +HTGE+P+ C  C  +  +  SLK H++ H                      
Sbjct: 363 SHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVKTHSADLLRLPCGICGKAFRDASYL 422

Query: 549 --HREQRSGAGP-GPPPEPP----------------------PPSQRGSAPQSGAKPSPQ 583
             H+   +GAG  GP P  P                      PP+    AP+ GA  +PQ
Sbjct: 423 LKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAAAEAPKDGAASAPQ 482

Query: 584 -PATWVEG--ASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAG 640
            P T+  G     P PP++ +   +    A     +     G A PL L   AG  G  G
Sbjct: 483 PPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVYGAVPVPLLG-AHPLLLG-GAGTSGAGG 540

Query: 641 PG----GALHRCLFCPFATGAPELMALHLQVHHSRRARGRRPPQ 680
            G    G    C  C    G  E +  H ++H      G +P Q
Sbjct: 541 SGASVPGKTFCCGICGRGFGRRETLKRHERIH-----TGEKPHQ 579



 Score = 87.8 bits (216), Expect = 3e-17
 Identities = 81/324 (25%), Positives = 109/324 (33%), Gaps = 39/324 (12%)

Query: 38  GSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQR 97
           G  G      S +    + F C +CG+ F     L  H R H G +  QCP CG R  + 
Sbjct: 531 GGAGTSGAGGSGASVPGKTFCCGICGRGFGRRETLKRHERIHTGEKPHQCPVCGKRFRES 590

Query: 98  ALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRAR------SSGGMQATPATEG 151
             L  H   H  ERP        +    ++L R  ++ R +       + G+ +T  T G
Sbjct: 591 FHLSKHHVVHTRERPYKCELCGKVFGYPQSLTRHRQVHRLQLPCALAGAAGLPSTQGTPG 650

Query: 152 LARPQAPSSSA-------FRCPYCKGKFRT--SAERERHLHILHRPWKCGLCSFGSSQEE 202
              P A  +SA       + C  C   F         + +H+  +P+ C  C       E
Sbjct: 651 ACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCDACGKTFGFIE 710

Query: 203 ELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEP-----------------RSVPQ 245
            L+ H L    APER L       PP P    PP                      +V  
Sbjct: 711 NLMWHKLVHQAAPERLL-------PPAPGGLQPPDGSSGTDAASVLDNGLAGEVGAAVAA 763

Query: 246 PEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACP 305
                  E       A A       P  F C  CGQSF     L  H   H       C 
Sbjct: 764 LAGVSGGEDAGGAAVAGAGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCG 823

Query: 306 VCGRCFKEPWFLKNHMKVHASKLG 329
           +CG+ F   + L  H + H  K G
Sbjct: 824 LCGQSFAGAYDLLLHRRSHRQKRG 847



 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 76/300 (25%), Positives = 102/300 (34%), Gaps = 54/300 (18%)

Query: 42   MGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLR 101
            +G V+        R   C +CG+ F     L LH R+H   + F+CP CG R  + ALL 
Sbjct: 805  LGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLM 864

Query: 102  SHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSS 161
             H R H  +RP          +  R  LR   L +                 R       
Sbjct: 865  RHQRCHTEQRP------YRCGVCGRGFLRSWYLRQ----------------HRVVHTGER 902

Query: 162  AFRCPYCKGKFRTSAE--RERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPL 219
            AF+C  C  +F  S+     R LH + RP +C  C         LL H     G  ER  
Sbjct: 903  AFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLG--ERAY 960

Query: 220  AATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVC 279
                                  SV + +   EP R                 PE RC  C
Sbjct: 961  RCEHCG---------KGFFYLSSVLRHQRAHEPPR-----------------PELRCPAC 994

Query: 280  GQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASG 339
             ++F    + + H+  H+      C  CG  F   + LK H   H  K   L  PG  +G
Sbjct: 995  LKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAH--KAENLGGPGAGAG 1052



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 21/60 (35%), Positives = 28/60 (46%)

Query: 500  CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
            CP C K+F+   + + HL  H G RP++C  C      +  LK H   H  E   G G G
Sbjct: 991  CPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAENLGGPGAG 1050



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 24/61 (39%), Positives = 31/61 (50%), Gaps = 7/61 (11%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
           C  CGK+FR   +L  H R+H GER Y+C HC       G   ++L    R QR+   P 
Sbjct: 934 CSACGKTFRYRSNLLEHQRLHLGERAYRCEHC-------GKGFFYLSSVLRHQRAHEPPR 986

Query: 560 P 560
           P
Sbjct: 987 P 987



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 25/59 (42%), Positives = 31/59 (52%), Gaps = 2/59 (3%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH--HREQRSGA 556
           C  CG+ F  + +L+ H  VHTGER +KC  C     QS SL  H + H   R QR  A
Sbjct: 878 CGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSA 936



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 25/65 (38%), Positives = 30/65 (46%)

Query: 493 RGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
           R   G  CP CGK F  A  L  H R HT +RPY+C  C     +S  L+ H   H  E+
Sbjct: 843 RQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGER 902

Query: 553 RSGAG 557
               G
Sbjct: 903 AFKCG 907



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 18/55 (32%), Positives = 24/55 (43%), Gaps = 1/55 (1%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554
           C  C K F  +  L  H R+H   RP +C  C        +L  H QR H  +R+
Sbjct: 906 CGVCAKRFAQSSSLAEHRRLHAVARPQRCSACGKTFRYRSNLLEH-QRLHLGERA 959


>gi|37622341 zinc finger protein 42 isoform 2 [Homo sapiens]
          Length = 734

 Score =  104 bits (260), Expect = 3e-22
 Identities = 128/497 (25%), Positives = 164/497 (32%), Gaps = 124/497 (24%)

Query: 59  CPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAAR 118
           C VCGK F   S L  H + H G + F C  CG   ++ + L  H  TH  ERP      
Sbjct: 358 CDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTEERP------ 411

Query: 119 LLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAER 178
                                                       F C  C   F  SA  
Sbjct: 412 --------------------------------------------FVCGDCGQGFVRSARL 427

Query: 179 ERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPP 236
           E H  +H   +P++C  C     Q   LL H    HG P  P     A PP  P    PP
Sbjct: 428 EEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQ-RIHGDPPGP----GAKPPAPPGAPEPP 482

Query: 237 QPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296
            P P S    E      R A      A          F C  CG+ F +   L  H R H
Sbjct: 483 GPFPCS----ECRESFARRAVLLEHQAVHT---GDKSFGCVECGERFGRRSVLLQHRRVH 535

Query: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEP 356
                 AC  CG+ F++   L  H ++H  +                 +P      A   
Sbjct: 536 SGERPFACAECGQSFRQRSNLTQHRRIHTGE-----------------RP-----FACAE 573

Query: 357 LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPA 416
            G A            R+ P+L  +L +  GE +P    A P  G+ F     L+     
Sbjct: 574 CGKAF-----------RQRPTLTQHLRVHTGE-KPF---ACPECGQRFSQRLKLTR---- 614

Query: 417 RARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPR--PGEGPGHSASAAGAQARST 474
             R H  E+P    E           G +  S  + H R   GE P  +    G   R  
Sbjct: 615 HQRTHTGEKPYHCGEC--------GLGFTQVSRLTEHQRIHTGERP-FACPECGQSFRQH 665

Query: 475 ATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYA 534
           A   ++  +  G RP          CP CGK+FR    L  HLR H  E+P+ C  C   
Sbjct: 666 ANLTQHRRIHTGERPYA--------CPECGKAFRQRPTLTQHLRTHRREKPFACQDCGRR 717

Query: 535 GTQSGSLKYHLQRHHRE 551
             QS  L  H + H  E
Sbjct: 718 FHQSTKLIQHQRVHSAE 734



 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 93/350 (26%), Positives = 117/350 (33%), Gaps = 109/350 (31%)

Query: 3   GSRPRAPSGHLAPSPP----------AFDGELDLQRYSNGPAVSAGSLGMGAVSWSES-- 50
           G++P AP G  AP PP          +F     L  +    AV  G    G V   E   
Sbjct: 469 GAKPPAPPG--APEPPGPFPCSECRESFARRAVLLEHQ---AVHTGDKSFGCVECGERFG 523

Query: 51  -----------RAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRAL 99
                       +GER F C  CG+ FR  S L  H R H G + F C  CG    QR  
Sbjct: 524 RRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPT 583

Query: 100 LRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPS 159
           L  HLR H  E+P                                               
Sbjct: 584 LTQHLRVHTGEKP----------------------------------------------- 596

Query: 160 SSAFRCPYCKGKF--RTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPER 217
              F CP C  +F  R    R +  H   +P+ CG C  G +Q   L  H     G  ER
Sbjct: 597 ---FACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQRIHTG--ER 651

Query: 218 PLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQ 277
           P A                    +S  Q     +  R  T        E P A PE    
Sbjct: 652 PFACPECG---------------QSFRQHANLTQHRRIHT-------GERPYACPE---- 685

Query: 278 VCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
            CG++F Q   L  H+R H+     AC  CGR F +   L  H +VH+++
Sbjct: 686 -CGKAFRQRPTLTQHLRTHRREKPFACQDCGRRFHQSTKLIQHQRVHSAE 734



 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 75/285 (26%), Positives = 101/285 (35%), Gaps = 26/285 (9%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
           ER F C  CG+ F  ++ L  H R H G Q F+C  CG    QR+ L  H R H    P 
Sbjct: 409 ERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGD--PP 466

Query: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQA--------PSSSAFRC 165
            P A+             A  G     G    +   E  AR               +F C
Sbjct: 467 GPGAK-----------PPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGC 515

Query: 166 PYCKGKF--RTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATS 223
             C  +F  R+   + R +H   RP+ C  C     Q   L  H     G  ERP A   
Sbjct: 516 VECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTG--ERPFACAE 573

Query: 224 AAPPPQPQPQPPPQPEPRSVPQPEPEPE-PEREATPTPAPAAPEEPPAPPEFRCQVCGQS 282
                + +P         +  +P   PE  +R +                 + C  CG  
Sbjct: 574 CGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLG 633

Query: 283 FTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
           FTQ   L  H R H      ACP CG+ F++   L  H ++H  +
Sbjct: 634 FTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLTQHRRIHTGE 678



 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 91/309 (29%), Positives = 117/309 (37%), Gaps = 43/309 (13%)

Query: 274 FRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRA 333
           F C  CGQ F +S  L+ H R H       C  CG+ F++   L  H ++H    GP   
Sbjct: 412 FVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAK 471

Query: 334 PGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPA-----------ERREPPS-LLGY 381
           P    G    P P             A+LL                  ER    S LL +
Sbjct: 472 PPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERFGRRSVLLQH 531

Query: 382 LSLRAGEGRPNGEGAEPGPG-----------RSFGGFRPLSSALPARARRHRAEEPEEEE 430
             + +GE RP    AE G             R   G RP + A   +A R R    +   
Sbjct: 532 RRVHSGE-RPFA-CAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPTLTQHLR 589

Query: 431 EVVEAEEETWAR---GRSLGSLASL--HPRP--GEGPGHSASAAGAQARSTATQEENGLL 483
             V   E+ +A    G+       L  H R   GE P H     G      +   E+  +
Sbjct: 590 --VHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGEC-GLGFTQVSRLTEHQRI 646

Query: 484 VGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKY 543
             G RP          CP CG+SFR   +L  H R+HTGERPY CP C  A  Q  +L  
Sbjct: 647 HTGERPFA--------CPECGQSFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQ 698

Query: 544 HLQRHHREQ 552
           HL+ H RE+
Sbjct: 699 HLRTHRREK 707



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 80/290 (27%), Positives = 110/290 (37%), Gaps = 35/290 (12%)

Query: 275 RCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAP 334
           RC VCG+ F+Q   L  H + H       C  CGR F     L  H   H  +  P    
Sbjct: 357 RCDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTEE-RPFVCG 415

Query: 335 GPASGPARAPQPPDLGLL--AYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPN 392
               G  R+ +  +   +    +P         A      R+  +LL +  +    G P 
Sbjct: 416 DCGQGFVRSARLEEHRRVHTGEQP------FRCAECGQSFRQRSNLLQHQRI---HGDPP 466

Query: 393 GEGAE----PGPGRSFGGFRPLSSALPARARR-----HRAEEPEEEE-EVVEAEEETWAR 442
           G GA+    PG     G F P S    + ARR     H+A    ++    VE  E     
Sbjct: 467 GPGAKPPAPPGAPEPPGPF-PCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERF--- 522

Query: 443 GRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPF 502
           GR    L       GE P  + +  G   R  +   ++  +  G RP          C  
Sbjct: 523 GRRSVLLQHRRVHSGERP-FACAECGQSFRQRSNLTQHRRIHTGERPFA--------CAE 573

Query: 503 CGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
           CGK+FR    L  HLRVHTGE+P+ CP C    +Q   L  H + H  E+
Sbjct: 574 CGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEK 623



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
           C  CG+ F  +  L+ H RVHTGE+P++C  C  +  Q  +L  H + H      GA P 
Sbjct: 414 CGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAKPP 473

Query: 560 PP---PEPPPPSQRGSAPQSGAK 579
            P   PEPP P       +S A+
Sbjct: 474 APPGAPEPPGPFPCSECRESFAR 496



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 2/67 (2%)

Query: 488 RPEGGRGAT-GKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQ 546
           RP  G G   G  C  CGK F    +L  H ++HTGERP+ C  C  + ++S  L  H Q
Sbjct: 345 RPSTGGGVVRGGRCDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRH-Q 403

Query: 547 RHHREQR 553
             H E+R
Sbjct: 404 LTHTEER 410



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 28/109 (25%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHRE-------- 551
           C  CG+SF  + HL  H   HT ERP+ C  C     +S  L+ H + H  E        
Sbjct: 386 CSECGRSFSRSSHLLRHQLTHTEERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAEC 445

Query: 552 -----QRS---------GAGPGPPPEPPPPSQRGSAPQSGAKPSPQPAT 586
                QRS         G  PGP  +PP P      P +   P P P +
Sbjct: 446 GQSFRQRSNLLQHQRIHGDPPGPGAKPPAP------PGAPEPPGPFPCS 488


>gi|37622345 zinc finger protein 42 isoform 1 [Homo sapiens]
          Length = 734

 Score =  104 bits (260), Expect = 3e-22
 Identities = 128/497 (25%), Positives = 164/497 (32%), Gaps = 124/497 (24%)

Query: 59  CPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAAR 118
           C VCGK F   S L  H + H G + F C  CG   ++ + L  H  TH  ERP      
Sbjct: 358 CDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTEERP------ 411

Query: 119 LLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAER 178
                                                       F C  C   F  SA  
Sbjct: 412 --------------------------------------------FVCGDCGQGFVRSARL 427

Query: 179 ERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPP 236
           E H  +H   +P++C  C     Q   LL H    HG P  P     A PP  P    PP
Sbjct: 428 EEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQ-RIHGDPPGP----GAKPPAPPGAPEPP 482

Query: 237 QPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296
            P P S    E      R A      A          F C  CG+ F +   L  H R H
Sbjct: 483 GPFPCS----ECRESFARRAVLLEHQAVHT---GDKSFGCVECGERFGRRSVLLQHRRVH 535

Query: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEP 356
                 AC  CG+ F++   L  H ++H  +                 +P      A   
Sbjct: 536 SGERPFACAECGQSFRQRSNLTQHRRIHTGE-----------------RP-----FACAE 573

Query: 357 LGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPA 416
            G A            R+ P+L  +L +  GE +P    A P  G+ F     L+     
Sbjct: 574 CGKAF-----------RQRPTLTQHLRVHTGE-KPF---ACPECGQRFSQRLKLTR---- 614

Query: 417 RARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPR--PGEGPGHSASAAGAQARST 474
             R H  E+P    E           G +  S  + H R   GE P  +    G   R  
Sbjct: 615 HQRTHTGEKPYHCGEC--------GLGFTQVSRLTEHQRIHTGERP-FACPECGQSFRQH 665

Query: 475 ATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYA 534
           A   ++  +  G RP          CP CGK+FR    L  HLR H  E+P+ C  C   
Sbjct: 666 ANLTQHRRIHTGERPYA--------CPECGKAFRQRPTLTQHLRTHRREKPFACQDCGRR 717

Query: 535 GTQSGSLKYHLQRHHRE 551
             QS  L  H + H  E
Sbjct: 718 FHQSTKLIQHQRVHSAE 734



 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 93/350 (26%), Positives = 117/350 (33%), Gaps = 109/350 (31%)

Query: 3   GSRPRAPSGHLAPSPP----------AFDGELDLQRYSNGPAVSAGSLGMGAVSWSES-- 50
           G++P AP G  AP PP          +F     L  +    AV  G    G V   E   
Sbjct: 469 GAKPPAPPG--APEPPGPFPCSECRESFARRAVLLEHQ---AVHTGDKSFGCVECGERFG 523

Query: 51  -----------RAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRAL 99
                       +GER F C  CG+ FR  S L  H R H G + F C  CG    QR  
Sbjct: 524 RRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPT 583

Query: 100 LRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPS 159
           L  HLR H  E+P                                               
Sbjct: 584 LTQHLRVHTGEKP----------------------------------------------- 596

Query: 160 SSAFRCPYCKGKF--RTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPER 217
              F CP C  +F  R    R +  H   +P+ CG C  G +Q   L  H     G  ER
Sbjct: 597 ---FACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQRIHTG--ER 651

Query: 218 PLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQ 277
           P A                    +S  Q     +  R  T        E P A PE    
Sbjct: 652 PFACPECG---------------QSFRQHANLTQHRRIHT-------GERPYACPE---- 685

Query: 278 VCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
            CG++F Q   L  H+R H+     AC  CGR F +   L  H +VH+++
Sbjct: 686 -CGKAFRQRPTLTQHLRTHRREKPFACQDCGRRFHQSTKLIQHQRVHSAE 734



 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 75/285 (26%), Positives = 101/285 (35%), Gaps = 26/285 (9%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
           ER F C  CG+ F  ++ L  H R H G Q F+C  CG    QR+ L  H R H    P 
Sbjct: 409 ERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGD--PP 466

Query: 114 SPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQA--------PSSSAFRC 165
            P A+             A  G     G    +   E  AR               +F C
Sbjct: 467 GPGAK-----------PPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGC 515

Query: 166 PYCKGKF--RTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATS 223
             C  +F  R+   + R +H   RP+ C  C     Q   L  H     G  ERP A   
Sbjct: 516 VECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTG--ERPFACAE 573

Query: 224 AAPPPQPQPQPPPQPEPRSVPQPEPEPE-PEREATPTPAPAAPEEPPAPPEFRCQVCGQS 282
                + +P         +  +P   PE  +R +                 + C  CG  
Sbjct: 574 CGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLG 633

Query: 283 FTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
           FTQ   L  H R H      ACP CG+ F++   L  H ++H  +
Sbjct: 634 FTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLTQHRRIHTGE 678



 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 91/309 (29%), Positives = 117/309 (37%), Gaps = 43/309 (13%)

Query: 274 FRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRA 333
           F C  CGQ F +S  L+ H R H       C  CG+ F++   L  H ++H    GP   
Sbjct: 412 FVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAK 471

Query: 334 PGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPA-----------ERREPPS-LLGY 381
           P    G    P P             A+LL                  ER    S LL +
Sbjct: 472 PPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERFGRRSVLLQH 531

Query: 382 LSLRAGEGRPNGEGAEPGPG-----------RSFGGFRPLSSALPARARRHRAEEPEEEE 430
             + +GE RP    AE G             R   G RP + A   +A R R    +   
Sbjct: 532 RRVHSGE-RPFA-CAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPTLTQHLR 589

Query: 431 EVVEAEEETWAR---GRSLGSLASL--HPRP--GEGPGHSASAAGAQARSTATQEENGLL 483
             V   E+ +A    G+       L  H R   GE P H     G      +   E+  +
Sbjct: 590 --VHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGEC-GLGFTQVSRLTEHQRI 646

Query: 484 VGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKY 543
             G RP          CP CG+SFR   +L  H R+HTGERPY CP C  A  Q  +L  
Sbjct: 647 HTGERPFA--------CPECGQSFRQHANLTQHRRIHTGERPYACPECGKAFRQRPTLTQ 698

Query: 544 HLQRHHREQ 552
           HL+ H RE+
Sbjct: 699 HLRTHRREK 707



 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 80/290 (27%), Positives = 110/290 (37%), Gaps = 35/290 (12%)

Query: 275 RCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAP 334
           RC VCG+ F+Q   L  H + H       C  CGR F     L  H   H  +  P    
Sbjct: 357 RCDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRHQLTHTEE-RPFVCG 415

Query: 335 GPASGPARAPQPPDLGLL--AYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPN 392
               G  R+ +  +   +    +P         A      R+  +LL +  +    G P 
Sbjct: 416 DCGQGFVRSARLEEHRRVHTGEQP------FRCAECGQSFRQRSNLLQHQRI---HGDPP 466

Query: 393 GEGAE----PGPGRSFGGFRPLSSALPARARR-----HRAEEPEEEE-EVVEAEEETWAR 442
           G GA+    PG     G F P S    + ARR     H+A    ++    VE  E     
Sbjct: 467 GPGAKPPAPPGAPEPPGPF-PCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERF--- 522

Query: 443 GRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPF 502
           GR    L       GE P  + +  G   R  +   ++  +  G RP          C  
Sbjct: 523 GRRSVLLQHRRVHSGERP-FACAECGQSFRQRSNLTQHRRIHTGERPFA--------CAE 573

Query: 503 CGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
           CGK+FR    L  HLRVHTGE+P+ CP C    +Q   L  H + H  E+
Sbjct: 574 CGKAFRQRPTLTQHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEK 623



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 30/83 (36%), Positives = 41/83 (49%), Gaps = 3/83 (3%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
           C  CG+ F  +  L+ H RVHTGE+P++C  C  +  Q  +L  H + H      GA P 
Sbjct: 414 CGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAKPP 473

Query: 560 PP---PEPPPPSQRGSAPQSGAK 579
            P   PEPP P       +S A+
Sbjct: 474 APPGAPEPPGPFPCSECRESFAR 496



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 2/67 (2%)

Query: 488 RPEGGRGAT-GKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQ 546
           RP  G G   G  C  CGK F    +L  H ++HTGERP+ C  C  + ++S  L  H Q
Sbjct: 345 RPSTGGGVVRGGRCDVCGKVFSQRSNLLRHQKIHTGERPFVCSECGRSFSRSSHLLRH-Q 403

Query: 547 RHHREQR 553
             H E+R
Sbjct: 404 LTHTEER 410



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 28/109 (25%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHRE-------- 551
           C  CG+SF  + HL  H   HT ERP+ C  C     +S  L+ H + H  E        
Sbjct: 386 CSECGRSFSRSSHLLRHQLTHTEERPFVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAEC 445

Query: 552 -----QRS---------GAGPGPPPEPPPPSQRGSAPQSGAKPSPQPAT 586
                QRS         G  PGP  +PP P      P +   P P P +
Sbjct: 446 GQSFRQRSNLLQHQRIHGDPPGPGAKPPAP------PGAPEPPGPFPCS 488


>gi|13376247 zinc finger protein 672 [Homo sapiens]
          Length = 452

 Score =  101 bits (252), Expect = 2e-21
 Identities = 128/515 (24%), Positives = 180/515 (34%), Gaps = 144/515 (27%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPER 111
           A  + + C  CGK F ++S+L  H RAH G   F+C  CG R A+ A LR+H RTH    
Sbjct: 9   AAGKPYSCSECGKSFCYSSVLLRHERAHGGDGRFRCLECGERCARAADLRAHRRTH---- 64

Query: 112 PRSPAARLLLELEERALLREARLGRA-RSSGGMQATPATEGLARPQAPSSSAFRCPYCKG 170
               A + L    E         G++ R SG +              P      C  C  
Sbjct: 65  ----AGQTLYICSE--------CGQSFRHSGRLDLHLGAHRQRCRTCP------CRTCGR 106

Query: 171 KFRTSAE---RERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPP 227
           +F          R  H+  RP +C LC+  + ++  LL H   AH     PL  TS    
Sbjct: 107 RFPHLPALLLHRRRQHLPERPRRCPLCA-RTFRQSALLFHQARAH-----PLGTTS---- 156

Query: 228 PQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSW 287
                                                  +P APP  RC  C ++F    
Sbjct: 157 ---------------------------------------DPAAPPH-RCAQCPRAFRSGA 176

Query: 288 FLKGHMRKH--------KASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASG 339
            L+ H R H        + S  H C VCG+CF +   L  H++ H+ +            
Sbjct: 177 GLRSHARIHVSRSPTRPRVSDAHQCGVCGKCFGKSSTLTRHLQTHSGEK----------- 225

Query: 340 PARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPG 399
           P + P+            G   L           E  +L+ +     GE +P   G    
Sbjct: 226 PFKCPE-----------CGKGFL-----------ESATLVRHQRTHTGE-KPYACG---D 259

Query: 400 PGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPR--PG 457
            GR F      SS L    R H+ E P            T  +G    S   +H R   G
Sbjct: 260 CGRCFSE----SSTLLRHRRSHQGERPHACA--------TCGKGFGQRSDLVVHQRIHTG 307

Query: 458 EGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHL 517
           E P  +    G +    +   ++     G +P          C  CGK F    +L VH 
Sbjct: 308 EKP-FACPECGRRFSDRSDLTKHRRTHTGEKPYR--------CELCGKRFTCVSNLNVHR 358

Query: 518 RVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQ 552
           R H G +P+KCP C  A + +  L  H + H  E+
Sbjct: 359 RNHAGHKPHKCPECSKAFSVASKLALHRKTHLGER 393



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 67/242 (27%), Positives = 93/242 (38%), Gaps = 30/242 (12%)

Query: 4   SRPRAPSGHLAPSPPAF--------DGELDLQRYSNGPAVS-AGSLGMGAVSWSES---- 50
           S P AP    A  P AF           + + R    P VS A   G+    + +S    
Sbjct: 156 SDPAAPPHRCAQCPRAFRSGAGLRSHARIHVSRSPTRPRVSDAHQCGVCGKCFGKSSTLT 215

Query: 51  -----RAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLR 105
                 +GE+ F CP CGK F  ++ L  H R H G + + C  CG   ++ + L  H R
Sbjct: 216 RHLQTHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACGDCGRCFSESSTLLRHRR 275

Query: 106 THQPERPRSPAA-------RLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAP 158
           +HQ ERP + A        R  L + +R    E         G   +  +     R    
Sbjct: 276 SHQGERPHACATCGKGFGQRSDLVVHQRIHTGEKPFA-CPECGRRFSDRSDLTKHRRTHT 334

Query: 159 SSSAFRCPYCKGKFR--TSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPE 216
               +RC  C  +F   ++    R  H  H+P KC  CS   S   +L  H  T  G  E
Sbjct: 335 GEKPYRCELCGKRFTCVSNLNVHRRNHAGHKPHKCPECSKAFSVASKLALHRKTHLG--E 392

Query: 217 RP 218
           RP
Sbjct: 393 RP 394



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 45/160 (28%), Positives = 58/160 (36%), Gaps = 24/160 (15%)

Query: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQP 109
           S  GER   C  CGK F   S L +H R H G + F CP CG R + R+ L  H RTH  
Sbjct: 276 SHQGERPHACATCGKGFGQRSDLVVHQRIHTGEKPFACPECGRRFSDRSDLTKHRRTHTG 335

Query: 110 ERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCK 169
           E+P                       R    G      +   + R         +CP C 
Sbjct: 336 EKPY----------------------RCELCGKRFTCVSNLNVHRRNHAGHKPHKCPECS 373

Query: 170 GKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHH 207
             F  +++   H   H+  RP +C  C    S    L  H
Sbjct: 374 KAFSVASKLALHRKTHLGERPAECAECGKCFSHSRSLSQH 413



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 70/289 (24%), Positives = 95/289 (32%), Gaps = 49/289 (16%)

Query: 274 FRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRA 333
           + C  CG+SF  S  L  H R H       C  CG        L+ H + HA        
Sbjct: 14  YSCSECGKSFCYSSVLLRHERAHGGDGRFRCLECGERCARAADLRAHRRTHA-------- 65

Query: 334 PGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNG 393
                                   G  L +      + R       G L L  G  R   
Sbjct: 66  ------------------------GQTLYICSECGQSFRHS-----GRLDLHLGAHR--- 93

Query: 394 EGAEPGPGRSFGG-FRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASL 452
           +     P R+ G  F  L + L  R R+H  E P            T+ +   L   A  
Sbjct: 94  QRCRTCPCRTCGRRFPHLPALLLHRRRQHLPERPRR----CPLCARTFRQSALLFHQARA 149

Query: 453 HP----RPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFR 508
           HP         P H  +      RS A    +  +     P   R +    C  CGK F 
Sbjct: 150 HPLGTTSDPAAPPHRCAQCPRAFRSGAGLRSHARIHVSRSPTRPRVSDAHQCGVCGKCFG 209

Query: 509 SAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAG 557
            +  L  HL+ H+GE+P+KCP C     +S +L  H + H  E+    G
Sbjct: 210 KSSTLTRHLQTHSGEKPFKCPECGKGFLESATLVRHQRTHTGEKPYACG 258



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 79/299 (26%), Positives = 103/299 (34%), Gaps = 40/299 (13%)

Query: 274 FRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLG--PL 331
           FRC  CG+   ++  L+ H R H     + C  CG+ F+    L  H+  H  +    P 
Sbjct: 42  FRCLECGERCARAADLRAHRRTHAGQTLYICSECGQSFRHSGRLDLHLGAHRQRCRTCPC 101

Query: 332 RAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTP-AERREPPSLLGYLSLRAGEGR 390
           R  G      R P  P L L       P     P   P   R    S L +   RA    
Sbjct: 102 RTCG-----RRFPHLPALLLHRRRQHLPE---RPRRCPLCARTFRQSALLFHQARA---H 150

Query: 391 PNGEGAEPG--PGRSFGGFRPLSSA--LPARARRHRAEEPEEEEEVVEAEEETWARGRSL 446
           P G  ++P   P R     R   S   L + AR H +  P      V    +    G+  
Sbjct: 151 PLGTTSDPAAPPHRCAQCPRAFRSGAGLRSHARIHVSRSPTRPR--VSDAHQCGVCGKCF 208

Query: 447 GSLASL----HPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKD--- 499
           G  ++L        GE P                    G L   T     R  TG+    
Sbjct: 209 GKSSTLTRHLQTHSGEKPFKCPECG------------KGFLESATLVRHQRTHTGEKPYA 256

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGP 558
           C  CG+ F  +  L  H R H GERP+ C  C     Q   L  H QR H  ++  A P
Sbjct: 257 CGDCGRCFSESSTLLRHRRSHQGERPHACATCGKGFGQRSDLVVH-QRIHTGEKPFACP 314



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 7/119 (5%)

Query: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQP 109
           +  GE+ + C +CGKRF   S L +H R H G +  +CP C    +  + L  H +TH  
Sbjct: 332 THTGEKPYRCELCGKRFTCVSNLNVHRRNHAGHKPHKCPECSKAFSVASKLALHRKTHLG 391

Query: 110 ERPRSPAARLLLELEERALLREARL-GRARSSGGMQATPAT------EGLARPQAPSSS 161
           ERP   A         R+L +  R   RAR++  +    A       EG A  + P  S
Sbjct: 392 ERPAECAECGKCFSHSRSLSQHQRAHTRARTAAAVAIQSAVGTALVFEGPAEQEKPGFS 450


>gi|46409310 zinc finger protein 467 [Homo sapiens]
          Length = 595

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 138/583 (23%), Positives = 190/583 (32%), Gaps = 135/583 (23%)

Query: 13  LAPSP-PAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSI 71
           L PSP PA D       Y   P       G+    W      E+ + C  C +RFR    
Sbjct: 117 LLPSPFPAPDLGHLAAAYKLEPGAPGALSGLALSGWGPMP--EKPYGCGECERRFRDQLT 174

Query: 72  LALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLRE 131
           L LH R H G     CP CG    QRA +  H R+H+ ERP  P +       ++   ++
Sbjct: 175 LRLHQRLHRGEGPCACPDCGRSFTQRAHMLLHQRSHRGERP-FPCSEC-----DKRFSKK 228

Query: 132 ARLGR-ARSSGGMQATPATE-----------GLARPQAPSSSAFRCPYCKGKFRTSAERE 179
           A L R  R+  G +  P  E           G  +        F C  C+ +FR      
Sbjct: 229 AHLTRHLRTHTGERPYPCAECGKRFSQKIHLGSHQKTHTGERPFPCTECEKRFRKKTHLI 288

Query: 180 RH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGA-PERPLAATSAAPPPQPQPQPPP 236
           RH  +H   RP++C  C+   + ++ L+ H      A P RP   +SA+P          
Sbjct: 289 RHQRIHTGERPYQCAQCARSFTHKQHLVRHQRVHQTAGPARPSPDSSASP---------- 338

Query: 237 QPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296
                                P+P P+     P P  F C  CG SF     L  H   H
Sbjct: 339 -----------------HSTAPSPTPSF----PGPKPFACSDCGLSFGWKKNLATHQCLH 377

Query: 297 KA-SFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYE 355
           ++      C  C         L   +   A+K       GP  GP   P  P        
Sbjct: 378 RSEGRPFGCDECA--------LGATVDAPAAKPLASAPGGPGCGPGSDPVVP-------- 421

Query: 356 PLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSA-- 413
                           +R P     +     G G  +G+     P R   G RP +    
Sbjct: 422 ----------------QRAPSGERSFFCPDCGRGFSHGQHLARHP-RVHTGERPFACTQC 464

Query: 414 ---------LPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSA 464
                    L A +R H    P    +        ++R   LG   ++H   G  P H+ 
Sbjct: 465 DRRFGSRPNLVAHSRAHSGARPFACAQC----GRRFSRKSHLGRHQAVH--TGSRP-HAC 517

Query: 465 SAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGER 524
           +       S      +  +  G+RP          CP CGKSF    HL  H  +H GE 
Sbjct: 518 AVCARSFSSKTNLVRHQAIHTGSRP--------FSCPQCGKSFSRKTHLVRHQLIH-GEA 568

Query: 525 PYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPP 567
            +  P    A                   + A   PP   PPP
Sbjct: 569 AHAAPDAALA-------------------APAWSAPPEVAPPP 592



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 142/537 (26%), Positives = 186/537 (34%), Gaps = 104/537 (19%)

Query: 231 QPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLK 290
           QP+  PQ EPR       E              +  E P P E      G    Q+   +
Sbjct: 17  QPEMAPQSEPREGSHNAQEQMSSSREERALGVCSGHEAPTPEE------GAHTEQA---E 67

Query: 291 GHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVH------------ASKLGPLRAPGPAS 338
              R    S   A PV G C  E W ++  +KV                L  L +P PA 
Sbjct: 68  APCRGQACSAQKAQPV-GTCPGEEWMIRK-VKVEDEDQEAEEEVEWPQHLSLLPSPFPA- 124

Query: 339 GPARAPQPPDLGLLA----YEPLGPALLLAPA-----PTP--------AERREPPSLLGY 381
                   PDLG LA     EP  P  L   A     P P         ERR        
Sbjct: 125 --------PDLGHLAAAYKLEPGAPGALSGLALSGWGPMPEKPYGCGECERR----FRDQ 172

Query: 382 LSLRAGEGRPNGEG--AEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEET 439
           L+LR  +    GEG  A P  GRSF       + +    R HR E P    E     ++ 
Sbjct: 173 LTLRLHQRLHRGEGPCACPDCGRSF----TQRAHMLLHQRSHRGERPFPCSEC----DKR 224

Query: 440 WARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKD 499
           +++   L     L    GE P   A      ++             G+  +   G     
Sbjct: 225 FSKKAHL--TRHLRTHTGERPYPCAECGKRFSQKIHL---------GSHQKTHTGERPFP 273

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
           C  C K FR   HL  H R+HTGERPY+C  C     +S + K HL RH R  ++ AGP 
Sbjct: 274 CTECEKRFRKKTHLIRHQRIHTGERPYQCAQC----ARSFTHKQHLVRHQRVHQT-AGPA 328

Query: 560 PPPEPPPPSQRGSAPQ-SGAKPSPQPATWVE-GASSPRPPSSGAGPGSRRKPASPGRTLR 617
            P      S   +AP  + + P P+P    + G S     +        R    P     
Sbjct: 329 RPSPDSSASPHSTAPSPTPSFPGPKPFACSDCGLSFGWKKNLATHQCLHRSEGRPFGCDE 388

Query: 618 NGRGGEAE-PLDLSLRAGPGGE-AGPGG---------ALHRCLFCP-----FATGAPELM 661
              G   + P    L + PGG   GPG          +  R  FCP     F+ G  + +
Sbjct: 389 CALGATVDAPAAKPLASAPGGPGCGPGSDPVVPQRAPSGERSFFCPDCGRGFSHG--QHL 446

Query: 662 ALHLQVHHSRRARG-----RRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPG 713
           A H +VH   R        RR         ++R  SG  P + +Q G   S  S  G
Sbjct: 447 ARHPRVHTGERPFACTQCDRRFGSRPNLVAHSRAHSGARPFACAQCGRRFSRKSHLG 503


>gi|133922582 zinc finger protein 358 [Homo sapiens]
          Length = 568

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 78/278 (28%), Positives = 101/278 (36%), Gaps = 64/278 (23%)

Query: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQP 109
           S +GE+   CPVCGK F   S+LA HLR H G +  +CP C     Q + L  HLRTH  
Sbjct: 228 SHSGEKPHHCPVCGKAFGHGSLLAQHLRTHGGPRPHKCPVCAKGFGQGSALLKHLRTHTG 287

Query: 110 ERPRSPAARLLLELEERALLREARLGRAR-------------SSGGMQATPATEGLARPQ 156
           ERP           +  ALL+  R   A               S  +Q         RP 
Sbjct: 288 ERPYPCPQCGKAFGQSSALLQHQRTHTAERPYRCPHCGKAFGQSSNLQHHLRIHTGERPY 347

Query: 157 APSSSAFRCPYCKGKFRTSAERERHLHIL--HRPWKCGLCSFGSSQEEELLHHSLTAHGA 214
           A       CP+C   F  S+   +HLH+    RP++C LC     Q   L  H     GA
Sbjct: 348 A-------CPHCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTKHKRVHEGA 400

Query: 215 PERPLAATSAA--------------PPPQPQP---------------------------- 232
                AA +AA              P    +P                            
Sbjct: 401 AAAAAAAAAAAAAAAAGLGLGPGLSPASMMRPGQVSLLGPDAVSVLGSGLGLSPGTSSGR 460

Query: 233 QPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPA 270
            P P   P ++P P  +P P   +TP+P P    +P A
Sbjct: 461 NPDPGSGPGTLPDPSSKPLPGSRSTPSPTPVESSDPKA 498



 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 113/431 (26%), Positives = 153/431 (35%), Gaps = 84/431 (19%)

Query: 55  RRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRS 114
           R F CP CG+ FR +S L+ H R H G + ++CP CG   +  A L  H   H   RP  
Sbjct: 149 RPFSCPDCGRAFRRSSGLSQHRRTHSGEKPYRCPDCGKSFSHGATLAQHRGIHTGARPYQ 208

Query: 115 PAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRT 174
            AA        +A    + L + RSS                        CP C   F  
Sbjct: 209 CAAC------GKAFGWRSTLLKHRSSHS----------------GEKPHHCPVCGKAFGH 246

Query: 175 SAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQP 232
            +   +HL  H   RP KC +C+ G  Q   LL H  T  G                 +P
Sbjct: 247 GSLLAQHLRTHGGPRPHKCPVCAKGFGQGSALLKHLRTHTGE----------------RP 290

Query: 233 QPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGH 292
            P PQ   ++  Q     + +R  T        E P     +RC  CG++F QS  L+ H
Sbjct: 291 YPCPQCG-KAFGQSSALLQHQRTHTA-------ERP-----YRCPHCGKAFGQSSNLQHH 337

Query: 293 MRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLR-------------------- 332
           +R H     +ACP C + F +   L  H+ VH+ +  P R                    
Sbjct: 338 LRIHTGERPYACPHCSKAFGQSSALLQHLHVHSGE-RPYRCQLCGKAFGQASSLTKHKRV 396

Query: 333 ---APGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEG 389
              A   A+  A A      GL     L PA ++ P        +  S+LG   L    G
Sbjct: 397 HEGAAAAAAAAAAAAAAAAAGLGLGPGLSPASMMRPGQVSLLGPDAVSVLG-SGLGLSPG 455

Query: 390 RPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSL 449
             +G   +PG G    G  P  S+ P    R        E    +A  +    G  L   
Sbjct: 456 TSSGRNPDPGSG---PGTLPDPSSKPLPGSRSTPSPTPVESSDPKAGHDA---GPDLVPS 509

Query: 450 ASLHPRPGEGP 460
             L P P   P
Sbjct: 510 PDLDPVPSPDP 520



 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 122/479 (25%), Positives = 162/479 (33%), Gaps = 116/479 (24%)

Query: 218 PLAATSAAPPPQPQPQP---PPQPEPRSVPQPEPEP-------EPEREATPTPAPAAPEE 267
           P++++    P    P P    P  +  S   P+ +P        P+  AT      AP  
Sbjct: 87  PMSSSFDLDPDVIGPVPLILDPNSDTLSPGDPKVDPISSGLTATPQVLATSPAVLPAPAS 146

Query: 268 PPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHA-S 326
           PP P  F C  CG++F +S  L  H R H     + CP CG+ F     L  H  +H  +
Sbjct: 147 PPRP--FSCPDCGRAFRRSSGLSQHRRTHSGEKPYRCPDCGKSFSHGATLAQHRGIHTGA 204

Query: 327 KLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRA 386
           +     A G A G           LL +            P   +     SLL       
Sbjct: 205 RPYQCAACGKAFGWRST-------LLKHRSSHSGEKPHHCPVCGKAFGHGSLLAQHLRTH 257

Query: 387 GEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSL 446
           G  RP+     P   + FG      SAL    R H  E P                    
Sbjct: 258 GGPRPH---KCPVCAKGFGQ----GSALLKHLRTHTGERP-------------------- 290

Query: 447 GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKS 506
                 +P P  G     S+A  Q + T T E         RP          CP CGK+
Sbjct: 291 ------YPCPQCGKAFGQSSALLQHQRTHTAE---------RPYR--------CPHCGKA 327

Query: 507 FRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHRE--------------- 551
           F  + +L+ HLR+HTGERPY CPHC  A  QS +L  HL  H  E               
Sbjct: 328 FGQSSNLQHHLRIHTGERPYACPHCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQA 387

Query: 552 ------QRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVE---------------- 589
                 +R   G          +   +A   G  P   PA+ +                 
Sbjct: 388 SSLTKHKRVHEGAAAAAAAAAAAAAAAAAGLGLGPGLSPASMMRPGQVSLLGPDAVSVLG 447

Query: 590 -------GASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGP 641
                  G SS R P  G+GPG+   P+S  + L   R   +     S     G +AGP
Sbjct: 448 SGLGLSPGTSSGRNPDPGSGPGTLPDPSS--KPLPGSRSTPSPTPVESSDPKAGHDAGP 504



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 61/220 (27%), Positives = 74/220 (33%), Gaps = 12/220 (5%)

Query: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP 112
           GER + CP C K F  +S L  HL  H G + ++C  CG    Q + L  H R H+    
Sbjct: 343 GERPYACPHCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTKHKRVHEGAAA 402

Query: 113 RSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKF 172
            + AA          L     LG   S   M   P    L  P A S          G  
Sbjct: 403 AAAAAAAAAAAAAAGL----GLGPGLSPASMMR-PGQVSLLGPDAVSVLGSGLGLSPG-- 455

Query: 173 RTSAERERHLH----ILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPP 228
            TS+ R          L  P    L    S+     +  S    G    P    S    P
Sbjct: 456 -TSSGRNPDPGSGPGTLPDPSSKPLPGSRSTPSPTPVESSDPKAGHDAGPDLVPSPDLDP 514

Query: 229 QPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEP 268
            P P P P P P   P   P+P      T +PA    E P
Sbjct: 515 VPSPDPDPVPSPDPNPVSCPDPCSPTRGTVSPALPTGESP 554



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 120/484 (24%), Positives = 160/484 (33%), Gaps = 78/484 (16%)

Query: 140 SGGMQATP---ATEGLARPQAPSSSA--FRCPYCKGKFRTSA--ERERHLHILHRPWKCG 192
           S G+ ATP   AT     P AP+S    F CP C   FR S+   + R  H   +P++C 
Sbjct: 124 SSGLTATPQVLATSPAVLP-APASPPRPFSCPDCGRAFRRSSGLSQHRRTHSGEKPYRCP 182

Query: 193 LCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEP 252
            C    S    L  H     GA     AA   A                           
Sbjct: 183 DCGKSFSHGATLAQHRGIHTGARPYQCAACGKA-------------------------FG 217

Query: 253 EREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFK 312
            R        +   E P      C VCG++F     L  H+R H     H CPVC + F 
Sbjct: 218 WRSTLLKHRSSHSGEKP----HHCPVCGKAFGHGSLLAQHLRTHGGPRPHKCPVCAKGFG 273

Query: 313 EPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAER 372
           +   L  H++ H    G    P P  G A         LL ++    A      P   + 
Sbjct: 274 QGSALLKHLRTHT---GERPYPCPQCGKAFGQSS---ALLQHQRTHTAERPYRCPHCGKA 327

Query: 373 -REPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEE 431
             +  +L  +L +  GE RP    A P   ++FG     SSAL      H  E P   + 
Sbjct: 328 FGQSSNLQHHLRIHTGE-RPY---ACPHCSKAFGQ----SSALLQHLHVHSGERPYRCQL 379

Query: 432 VVEAEEETWARGRSLGSLASL--HPRPGEGPGHSASAAGAQARSTATQEENGLLVG-GTR 488
                      G++ G  +SL  H R  EG   +A+AA A A + A     GL +G G  
Sbjct: 380 C----------GKAFGQASSLTKHKRVHEGAAAAAAAAAAAAAAAAA----GLGLGPGLS 425

Query: 489 PE-----GGRGATGKDC-PFCGKSFRSAHHLKVHLRVHTGERPYKCPHCD---YAGTQSG 539
           P      G     G D     G     +           G  P   P        G++S 
Sbjct: 426 PASMMRPGQVSLLGPDAVSVLGSGLGLSPGTSSGRNPDPGSGPGTLPDPSSKPLPGSRST 485

Query: 540 SLKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSS 599
                ++    +    AGP   P P         P     P P P +  +  S  R   S
Sbjct: 486 PSPTPVESSDPKAGHDAGPDLVPSPDLDPVPSPDPDPVPSPDPNPVSCPDPCSPTRGTVS 545

Query: 600 GAGP 603
            A P
Sbjct: 546 PALP 549



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 89/346 (25%), Positives = 119/346 (34%), Gaps = 80/346 (23%)

Query: 398 PGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPG 457
           P  GR+F      SS L    R H  E+P    +      ++++ G +L     +H   G
Sbjct: 154 PDCGRAFRR----SSGLSQHRRTHSGEKPYRCPDC----GKSFSHGATLAQHRGIHT--G 203

Query: 458 EGPGHSASAAGAQA-RSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVH 516
             P   A+   A   RST  +  +     G +P          CP CGK+F     L  H
Sbjct: 204 ARPYQCAACGKAFGWRSTLLKHRSSH--SGEKPH--------HCPVCGKAFGHGSLLAQH 253

Query: 517 LRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSA-PQ 575
           LR H G RP+KCP C     Q  +L  HL+ H  E+           P P  Q G A  Q
Sbjct: 254 LRTHGGPRPHKCPVCAKGFGQGSALLKHLRTHTGER-----------PYPCPQCGKAFGQ 302

Query: 576 SGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRG-GEAEPLDLSLRAG 634
           S A    Q     E                      P R    G+  G++  L   LR  
Sbjct: 303 SSALLQHQRTHTAE---------------------RPYRCPHCGKAFGQSSNLQHHLRIH 341

Query: 635 PGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRAR-----GRRPPQADASPPYAR 689
            G         + C  C  A G    +  HL VH   R       G+   QA +   + R
Sbjct: 342 TGERP------YACPHCSKAFGQSSALLQHLHVHSGERPYRCQLCGKAFGQASSLTKHKR 395

Query: 690 VPSGETPPSPSQEGEE---------GSGLS-----RPGEAGLGGQE 721
           V  G    + +              G GLS     RPG+  L G +
Sbjct: 396 VHEGAAAAAAAAAAAAAAAAAGLGLGPGLSPASMMRPGQVSLLGPD 441


>gi|38348236 zinc finger protein 497 [Homo sapiens]
          Length = 498

 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 109/433 (25%), Positives = 151/433 (34%), Gaps = 53/433 (12%)

Query: 138 RSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAE--RERHLHILHRPWKCGLCS 195
           R   G ++ PA   L     P     RC  C   F   +   + R +H   +P+ C  C 
Sbjct: 81  RDGAGPRSEPADRALRPSPLPEEPGCRCGECGKAFSQGSYLLQHRRVHTGEKPYTCPECG 140

Query: 196 FGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPERE 255
              +    L  H     G  E+P A        + Q Q     E  S  +P   P+  + 
Sbjct: 141 KAFAWSSNLSQHQRIHSG--EKPYACRECGKAFRAQSQLIHHQETHSGLKPFRCPDCGKS 198

Query: 256 -ATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEP 314
               T              + C  CG++F+ +     H R H  +  HAC  CG+ F + 
Sbjct: 199 FGRSTTLVQHRRTHTGEKPYECPECGKAFSWNSNFLEHRRVHTGARPHACRDCGKAFSQS 258

Query: 315 WFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLG----PALLLAPAPTPA 370
             L  H+K+HA               AR    PD G       G         +  P P 
Sbjct: 259 SNLAEHLKIHAG--------------ARPHACPDCGKAFVRVAGLRQHRRTHSSEKPFPC 304

Query: 371 ER-----REPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEE 425
                  RE   LL +     GE RP  E AE G     G +      L    R H  E+
Sbjct: 305 AECGKAFRESSQLLQHQRTHTGE-RP-FECAECGQAFVMGSY------LAEHRRVHTGEK 356

Query: 426 PEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASA-AGAQARSTATQEENGLLV 484
           P    +  +A  +   R   L      H R   G    A A  G   R ++    + L  
Sbjct: 357 PHACAQCGKASSQ---RSNLLS-----HRRTHSGAKPFACADCGKAFRGSSGLAHHRLSH 408

Query: 485 GGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYH 544
            G RP          C  CGK+FR +  L+ H R+H+GERP+ C HC  A  +   L  H
Sbjct: 409 TGERPFA--------CAECGKAFRGSSELRQHQRLHSGERPFVCAHCSKAFVRKSELLSH 460

Query: 545 LQRHHREQRSGAG 557
            + H  E+    G
Sbjct: 461 RRTHTGERPYACG 473



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 84/311 (27%), Positives = 114/311 (36%), Gaps = 40/311 (12%)

Query: 44  AVSWSES-------RAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQ 96
           A +WS +        +GE+ + C  CGK FR  S L  H   H G + F+CP CG    +
Sbjct: 142 AFAWSSNLSQHQRIHSGEKPYACRECGKAFRAQSQLIHHQETHSGLKPFRCPDCGKSFGR 201

Query: 97  RALLRSHLRTHQPERP-RSPAARLLLE-----LEERALLREARLGRARSSGG--MQATPA 148
              L  H RTH  E+P   P            LE R +   AR    R  G    Q++  
Sbjct: 202 STTLVQHRRTHTGEKPYECPECGKAFSWNSNFLEHRRVHTGARPHACRDCGKAFSQSSNL 261

Query: 149 TEGL-----ARPQAPSSSAFRCPYCKGKFRTSA--ERERHLHILHRPWKCGLCSFGSSQE 201
            E L     ARP A       CP C   F   A   + R  H   +P+ C  C     + 
Sbjct: 262 AEHLKIHAGARPHA-------CPDCGKAFVRVAGLRQHRRTHSSEKPFPCAECGKAFRES 314

Query: 202 EELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPA 261
            +LL H  T  G  ERP          Q         E R V   E +P    +     +
Sbjct: 315 SQLLQHQRTHTG--ERPFECAECG---QAFVMGSYLAEHRRVHTGE-KPHACAQCGKASS 368

Query: 262 PAA-----PEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWF 316
             +              F C  CG++F  S  L  H   H      AC  CG+ F+    
Sbjct: 369 QRSNLLSHRRTHSGAKPFACADCGKAFRGSSGLAHHRLSHTGERPFACAECGKAFRGSSE 428

Query: 317 LKNHMKVHASK 327
           L+ H ++H+ +
Sbjct: 429 LRQHQRLHSGE 439



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 82/303 (27%), Positives = 106/303 (34%), Gaps = 46/303 (15%)

Query: 44  AVSWSES-------RAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQ 96
           A SW+ +         G R   C  CGK F  +S LA HL+ H GA+   CP CG    +
Sbjct: 226 AFSWNSNFLEHRRVHTGARPHACRDCGKAFSQSSNLAEHLKIHAGARPHACPDCGKAFVR 285

Query: 97  RALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRA-RSSGGMQATPATEGLARP 155
            A LR H RTH  E+P                   A  G+A R S  +     T    RP
Sbjct: 286 VAGLRQHRRTHSSEKP----------------FPCAECGKAFRESSQLLQHQRTHTGERP 329

Query: 156 QAPSSSAFRCPYCKGKFRTSA--ERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHG 213
                  F C  C   F   +     R +H   +P  C  C   SSQ   LL H  T  G
Sbjct: 330 -------FECAECGQAFVMGSYLAEHRRVHTGEKPHACAQCGKASSQRSNLLSHRRTHSG 382

Query: 214 APERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPER------EATPTPAPAAPEE 267
           A  +P A        +            +  +P    E  +      E        + E 
Sbjct: 383 A--KPFACADCGKAFRGSSGLAHHRLSHTGERPFACAECGKAFRGSSELRQHQRLHSGER 440

Query: 268 PPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
           P     F C  C ++F +   L  H R H     +AC  CG+ F     L  H K H  +
Sbjct: 441 P-----FVCAHCSKAFVRKSELLSHRRTHTGERPYACGECGKPFSHRCNLNEHQKRHGGR 495

Query: 328 LGP 330
             P
Sbjct: 496 AAP 498



 Score = 83.6 bits (205), Expect = 6e-16
 Identities = 81/329 (24%), Positives = 110/329 (33%), Gaps = 34/329 (10%)

Query: 2   EGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCPV 61
           +G+ PR+     A  P     E   +    G A S GS     +       GE+ + CP 
Sbjct: 82  DGAGPRSEPADRALRPSPLPEEPGCRCGECGKAFSQGSY---LLQHRRVHTGEKPYTCPE 138

Query: 62  CGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLL 121
           CGK F ++S L+ H R H G + + C  CG     ++ L  H  TH   +P         
Sbjct: 139 CGKAFAWSSNLSQHQRIHSGEKPYACRECGKAFRAQSQLIHHQETHSGLKP--------- 189

Query: 122 ELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAE--RE 179
                         R    G       T    R        + CP C   F  ++     
Sbjct: 190 -------------FRCPDCGKSFGRSTTLVQHRRTHTGEKPYECPECGKAFSWNSNFLEH 236

Query: 180 RHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPE 239
           R +H   RP  C  C    SQ   L  H     GA  RP A                   
Sbjct: 237 RRVHTGARPHACRDCGKAFSQSSNLAEHLKIHAGA--RPHACPDCGKAFVRVAGLRQHRR 294

Query: 240 PRSVPQPEPEPE---PEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKH 296
             S  +P P  E     RE++             P  F C  CGQ+F    +L  H R H
Sbjct: 295 THSSEKPFPCAECGKAFRESSQLLQHQRTHTGERP--FECAECGQAFVMGSYLAEHRRVH 352

Query: 297 KASFDHACPVCGRCFKEPWFLKNHMKVHA 325
                HAC  CG+   +   L +H + H+
Sbjct: 353 TGEKPHACAQCGKASSQRSNLLSHRRTHS 381



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 40/132 (30%), Positives = 55/132 (41%), Gaps = 24/132 (18%)

Query: 423 AEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPG--EGPGHSASAAGAQARSTATQEEN 480
           A + + ++  + A +E    GR LG      P  G  +G G  +  A    R +   EE 
Sbjct: 51  AGDGQRQQATLGAADEQGGPGRELG------PADGGRDGAGPRSEPADRALRPSPLPEEP 104

Query: 481 GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS 540
           G                  C  CGK+F    +L  H RVHTGE+PY CP C  A   S +
Sbjct: 105 GCR----------------CGECGKAFSQGSYLLQHRRVHTGEKPYTCPECGKAFAWSSN 148

Query: 541 LKYHLQRHHREQ 552
           L  H + H  E+
Sbjct: 149 LSQHQRIHSGEK 160



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 29/76 (38%), Positives = 37/76 (48%)

Query: 37  AGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQ 96
           A S     +S   + +G + F C  CGK FR +S LA H  +H G + F C  CG     
Sbjct: 366 ASSQRSNLLSHRRTHSGAKPFACADCGKAFRGSSGLAHHRLSHTGERPFACAECGKAFRG 425

Query: 97  RALLRSHLRTHQPERP 112
            + LR H R H  ERP
Sbjct: 426 SSELRQHQRLHSGERP 441



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 67/252 (26%), Positives = 90/252 (35%), Gaps = 48/252 (19%)

Query: 329 GPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGE 388
           GP R  GPA G      P        EP   AL  +P P      EP    G       +
Sbjct: 69  GPGRELGPADGGRDGAGPRS------EPADRALRPSPLP-----EEPGCRCGECGKAFSQ 117

Query: 389 G------RPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEA------- 435
           G      R    G +P      G     SS L    R H  E+P    E  +A       
Sbjct: 118 GSYLLQHRRVHTGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPYACRECGKAFRAQSQL 177

Query: 436 --EEETWAR---------GRSLGSLASL--HPRP--GEGPGHSASAAGAQARSTATQEEN 480
              +ET +          G+S G   +L  H R   GE P +     G      +   E+
Sbjct: 178 IHHQETHSGLKPFRCPDCGKSFGRSTTLVQHRRTHTGEKP-YECPECGKAFSWNSNFLEH 236

Query: 481 GLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGS 540
             +  G RP          C  CGK+F  + +L  HL++H G RP+ CP C  A  +   
Sbjct: 237 RRVHTGARPHA--------CRDCGKAFSQSSNLAEHLKIHAGARPHACPDCGKAFVRVAG 288

Query: 541 LKYHLQRHHREQ 552
           L+ H + H  E+
Sbjct: 289 LRQHRRTHSSEK 300



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 12/100 (12%)

Query: 602 GPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELM 661
           GPG    PA  GR   +G G  +EP D +LR  P  E  PG    RC  C  A      +
Sbjct: 69  GPGRELGPADGGR---DGAGPRSEPADRALRPSPLPEE-PG---CRCGECGKAFSQGSYL 121

Query: 662 ALHLQVHHSRRAR-----GRRPPQADASPPYARVPSGETP 696
             H +VH   +       G+    +     + R+ SGE P
Sbjct: 122 LQHRRVHTGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKP 161


>gi|7657693 zinc finger protein 324 [Homo sapiens]
          Length = 553

 Score = 97.1 bits (240), Expect = 5e-20
 Identities = 88/346 (25%), Positives = 122/346 (35%), Gaps = 66/346 (19%)

Query: 41  GMGAVSWSES----RAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQ 96
           G    +W E      AGE+ F C  C K F  +S L  HLR H G + ++C  CG   +Q
Sbjct: 237 GQEPSTWDELGEALHAGEKSFECRACSKVFVKSSDLLKHLRTHTGERPYECAQCGKAFSQ 296

Query: 97  RALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQ 156
            + L  H R H  E P +            +L+R  R+  A  S                
Sbjct: 297 TSHLTQHQRIHSGETPYACPVCGKAFRHSSSLVRHQRIHTAEKS---------------- 340

Query: 157 APSSSAFRCPYCKGKFR--TSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGA 214
                 FRC  C   F   ++  + R +H   RP+ C  C     +   L+ H  T  G 
Sbjct: 341 ------FRCSECGKAFSHGSNLSQHRKIHAGGRPYACAQCGRRFCRNSHLIQHERTHTG- 393

Query: 215 PERPL------AATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEP 268
            E+P       AA S         +     +P + PQ           T        E P
Sbjct: 394 -EKPFVCALCGAAFSQGSSLFKHQRVHTGEKPFACPQCGRAFSHSSNLTQHQLLHTGERP 452

Query: 269 PAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKL 328
                FRC  CG++F +   L  H R H       C  CGR F+E   L +H ++H  + 
Sbjct: 453 -----FRCVDCGKAFAKGAVLLSHRRIHTGEKPFVCTQCGRAFRERPALFHHQRIHTGEK 507

Query: 329 GPLRA-------------------------PGPASGPARAPQPPDL 349
              R+                         P PASGPA   QP ++
Sbjct: 508 TVRRSRASLHPQARSVAGASSEGAPAKETEPTPASGPAAVSQPAEV 553



 Score = 73.2 bits (178), Expect = 8e-13
 Identities = 84/324 (25%), Positives = 119/324 (36%), Gaps = 69/324 (21%)

Query: 274 FRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRA 333
           + C  CG++F+Q+  L  H R H     +ACPVCG+ F+    L  H ++H ++      
Sbjct: 285 YECAQCGKAFSQTSHLTQHQRIHSGETPYACPVCGKAFRHSSSLVRHQRIHTAEKS---- 340

Query: 334 PGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNG 393
                                   G A                +L  +  + AG GRP  
Sbjct: 341 ------------------FRCSECGKAF-----------SHGSNLSQHRKIHAG-GRPY- 369

Query: 394 EGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLH 453
             A    GR F      +S L    R H  E+P     V       +++G SL     +H
Sbjct: 370 --ACAQCGRRFCR----NSHLIQHERTHTGEKPF----VCALCGAAFSQGSSLFKHQRVH 419

Query: 454 PRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHL 513
              GE P  +    G     ++   ++ LL  G RP          C  CGK+F     L
Sbjct: 420 T--GEKP-FACPQCGRAFSHSSNLTQHQLLHTGERPFR--------CVDCGKAFAKGAVL 468

Query: 514 KVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHH------REQRSGAGP------GPP 561
             H R+HTGE+P+ C  C  A  +  +L +H QR H      R  R+   P      G  
Sbjct: 469 LSHRRIHTGEKPFVCTQCGRAFRERPAL-FHHQRIHTGEKTVRRSRASLHPQARSVAGAS 527

Query: 562 PEPPPPSQRGSAPQSGAKPSPQPA 585
            E  P  +    P SG     QPA
Sbjct: 528 SEGAPAKETEPTPASGPAAVSQPA 551



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 43/138 (31%), Positives = 60/138 (43%), Gaps = 8/138 (5%)

Query: 36  SAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAA 95
           +A S G           GE+ F CP CG+ F  +S L  H   H G + F+C  CG   A
Sbjct: 404 AAFSQGSSLFKHQRVHTGEKPFACPQCGRAFSHSSNLTQHQLLHTGERPFRCVDCGKAFA 463

Query: 96  QRALLRSHLRTHQPERP-------RSPAARLLLELEERALLREARLGRARSSGGMQATPA 148
           + A+L SH R H  E+P       R+   R  L   +R    E  + R+R+S   QA  +
Sbjct: 464 KGAVLLSHRRIHTGEKPFVCTQCGRAFRERPALFHHQRIHTGEKTVRRSRASLHPQAR-S 522

Query: 149 TEGLARPQAPSSSAFRCP 166
             G +   AP+      P
Sbjct: 523 VAGASSEGAPAKETEPTP 540



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 56/196 (28%), Positives = 74/196 (37%), Gaps = 26/196 (13%)

Query: 368 TPAERREPPSLLGY----LSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRA 423
           +P+  R+P  +       L L +G G+ +       P R   G R     L   A   R 
Sbjct: 129 SPSRERKPTGVSVIYWERLLLGSGSGQASVSLRLTSPLRPPEGVRLREKTLTEHALLGRQ 188

Query: 424 EEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLL 483
               E ++    E      GR+ GS   L    G G            R  A  +E   L
Sbjct: 189 PRTPERQKPCAQE----VPGRTFGSAQDLEAAGGRG----------HHRMGAVWQEPHRL 234

Query: 484 VGGTRP----EGGR----GATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAG 535
           +GG  P    E G     G    +C  C K F  +  L  HLR HTGERPY+C  C  A 
Sbjct: 235 LGGQEPSTWDELGEALHAGEKSFECRACSKVFVKSSDLLKHLRTHTGERPYECAQCGKAF 294

Query: 536 TQSGSLKYHLQRHHRE 551
           +Q+  L  H + H  E
Sbjct: 295 SQTSHLTQHQRIHSGE 310



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 58/210 (27%), Positives = 78/210 (37%), Gaps = 36/210 (17%)

Query: 345 QPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSF 404
           +PP+   L  + L    LL   P   ER++P                    A+  PGR+F
Sbjct: 167 RPPEGVRLREKTLTEHALLGRQPRTPERQKPC-------------------AQEVPGRTF 207

Query: 405 GGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSA 464
           G  + L +A      R  A   E    +   E  TW                GE      
Sbjct: 208 GSAQDLEAAGGRGHHRMGAVWQEPHRLLGGQEPSTW-------------DELGEALHAGE 254

Query: 465 SAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGER 524
            +   +A S    + + LL       G R     +C  CGK+F    HL  H R+H+GE 
Sbjct: 255 KSFECRACSKVFVKSSDLLKHLRTHTGERPY---ECAQCGKAFSQTSHLTQHQRIHSGET 311

Query: 525 PYKCPHCDYAGTQSGSLKYHLQRHHREQRS 554
           PY CP C  A   S SL  H QR H  ++S
Sbjct: 312 PYACPVCGKAFRHSSSLVRH-QRIHTAEKS 340



 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 47/161 (29%), Positives = 60/161 (37%), Gaps = 14/161 (8%)

Query: 411 SSALPARARRHRAEEPEEEEEVVEAEEETWARGRSL----GSLASLHPRPGEGPGHSASA 466
           SS L    R H  E P E  +  +A  +T    +      G      P  G+   HS+S 
Sbjct: 269 SSDLLKHLRTHTGERPYECAQCGKAFSQTSHLTQHQRIHSGETPYACPVCGKAFRHSSSL 328

Query: 467 AGAQARSTATQEENGLLVGGTRPEGGR---------GATGKDCPFCGKSFRSAHHLKVHL 517
              Q   TA +       G     G           G     C  CG+ F    HL  H 
Sbjct: 329 VRHQRIHTAEKSFRCSECGKAFSHGSNLSQHRKIHAGGRPYACAQCGRRFCRNSHLIQHE 388

Query: 518 RVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGP 558
           R HTGE+P+ C  C  A +Q  SL  H QR H  ++  A P
Sbjct: 389 RTHTGEKPFVCALCGAAFSQGSSLFKH-QRVHTGEKPFACP 428


>gi|34147544 zinc finger protein HIT-39 [Homo sapiens]
          Length = 500

 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 78/274 (28%), Positives = 105/274 (38%), Gaps = 33/274 (12%)

Query: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP 112
           GE+ + CP CG+ FR +  LA H   H G +  QCP CG R A  +LL  H RTH  E+P
Sbjct: 229 GEKPYHCPDCGRCFRRSRSLANHRTTHTGEKPHQCPSCGRRFAYPSLLAIHQRTHTGEKP 288

Query: 113 RSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKF 172
            +      LE   R   R A +   R   G +  P                 CP C+ +F
Sbjct: 289 YT-----CLECNRRFRQRTALVIHQRIHTGEKPYP-----------------CPDCERRF 326

Query: 173 RTSAE--RERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQP 230
            +S+     R +H   RP+ C  C    SQ   LL H L   G  E+P          + 
Sbjct: 327 SSSSRLVSHRRVHSGERPYACEHCEARFSQRSTLLQHQLLHTG--EKPYPCPDCG---RA 381

Query: 231 QPQPPPQPEPRSVPQPEP----EPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQS 286
             +       RS    E     +    R A P+   +          + C +C + F Q 
Sbjct: 382 FRRSGSLAIHRSTHTEEKLHACDDCGRRFAYPSLLASHRRVHSGERPYACDLCSKRFAQW 441

Query: 287 WFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNH 320
             L  H   H       C  CGRCF++ W L  H
Sbjct: 442 SHLAQHQLLHTGEKPFPCLECGRCFRQRWSLAVH 475



 Score = 89.7 bits (221), Expect = 8e-18
 Identities = 76/282 (26%), Positives = 105/282 (37%), Gaps = 37/282 (13%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
           ++ +PCP CG+RF + S+L  H RAH G   + C  CG R +QR  L  H   H  E+P 
Sbjct: 174 KKPYPCPDCGRRFSYPSLLVSHRRAHSGECPYVCDQCGKRFSQRKNLSQHQVIHTGEKPY 233

Query: 114 --SPAARLLLELEERALLREARLG----RARSSGGMQATPATEGLARPQAPSSSAFRCPY 167
                 R        A  R    G    +  S G   A P+   + +        + C  
Sbjct: 234 HCPDCGRCFRRSRSLANHRTTHTGEKPHQCPSCGRRFAYPSLLAIHQRTHTGEKPYTCLE 293

Query: 168 CKGKF--RTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAA 225
           C  +F  RT+    + +H   +P+ C  C    S    L+ H     G  ERP A     
Sbjct: 294 CNRRFRQRTALVIHQRIHTGEKPYPCPDCERRFSSSSRLVSHRRVHSG--ERPYACEHC- 350

Query: 226 PPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQ 285
                        E R           +R            E P P    C  CG++F +
Sbjct: 351 -------------EARF---------SQRSTLLQHQLLHTGEKPYP----CPDCGRAFRR 384

Query: 286 SWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASK 327
           S  L  H   H     HAC  CGR F  P  L +H +VH+ +
Sbjct: 385 SGSLAIHRSTHTEEKLHACDDCGRRFAYPSLLASHRRVHSGE 426



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 75/284 (26%), Positives = 101/284 (35%), Gaps = 30/284 (10%)

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPG 335
           C  CG+ F+Q   L  H   H     + CP CGRCF+    L NH   H  +  P + P 
Sbjct: 207 CDQCGKRFSQRKNLSQHQVIHTGEKPYHCPDCGRCFRRSRSLANHRTTHTGEK-PHQCP- 264

Query: 336 PASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEG 395
             S   R   P  L +      G              R+  +L+ +  +  GE       
Sbjct: 265 --SCGRRFAYPSLLAIHQRTHTGEKPYTC-LECNRRFRQRTALVIHQRIHTGE------- 314

Query: 396 AEPGPGRSFGGFRPLSSALPARARRHRAEEPE--EEEEVVEAEEETWARGRSLGSLASLH 453
            +P P          SS L +  R H  E P   E  E   ++  T  + + L +    +
Sbjct: 315 -KPYPCPDCERRFSSSSRLVSHRRVHSGERPYACEHCEARFSQRSTLLQHQLLHTGEKPY 373

Query: 454 PRPGEGPGHSASAAGAQARSTATQEE-------------NGLLVGGTRPEGGRGATGKDC 500
           P P  G     S + A  RST T+E+               LL    R   G       C
Sbjct: 374 PCPDCGRAFRRSGSLAIHRSTHTEEKLHACDDCGRRFAYPSLLASHRRVHSGERPYA--C 431

Query: 501 PFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYH 544
             C K F    HL  H  +HTGE+P+ C  C     Q  SL  H
Sbjct: 432 DLCSKRFAQWSHLAQHQLLHTGEKPFPCLECGRCFRQRWSLAVH 475



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 53/185 (28%), Positives = 77/185 (41%), Gaps = 26/185 (14%)

Query: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQP 109
           +  GE+ + C  C +RFR  + L +H R H G + + CP C  R +  + L SH R H  
Sbjct: 282 THTGEKPYTCLECNRRFRQRTALVIHQRIHTGEKPYPCPDCERRFSSSSRLVSHRRVHSG 341

Query: 110 ERPRSPAARLLLELEERALLREARL-------------GRA-RSSGGMQATPATEGLARP 155
           ERP +          +R+ L + +L             GRA R SG +    +T    + 
Sbjct: 342 ERPYA-CEHCEARFSQRSTLLQHQLLHTGEKPYPCPDCGRAFRRSGSLAIHRSTHTEEKL 400

Query: 156 QAPSSSAFRCPYCKGKFRTSA--ERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHG 213
            A       C  C  +F   +     R +H   RP+ C LCS   +Q   L  H L   G
Sbjct: 401 HA-------CDDCGRRFAYPSLLASHRRVHSGERPYACDLCSKRFAQWSHLAQHQLLHTG 453

Query: 214 APERP 218
             E+P
Sbjct: 454 --EKP 456



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 82/316 (25%), Positives = 110/316 (34%), Gaps = 34/316 (10%)

Query: 239 EPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKA 298
           E    P  E   + +R   P+     P +    P   C  CG +F     L+ H      
Sbjct: 116 EKEVFPPKEAPRKGKRGRRPSKPRLIPRQTSGGPI--CPDCGCTFPDHQALESHKCAQNL 173

Query: 299 SFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLG 358
              + CP CGR F  P  L +H + H+   G         G  R  Q  +L        G
Sbjct: 174 KKPYPCPDCGRRFSYPSLLVSHRRAHS---GECPYVCDQCG-KRFSQRKNLSQHQVIHTG 229

Query: 359 PALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARA 418
                 P      RR   SL  + +   GE +P+     P  GR F       S L    
Sbjct: 230 EKPYHCPDCGRCFRRS-RSLANHRTTHTGE-KPH---QCPSCGRRFA----YPSLLAIHQ 280

Query: 419 RRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPR--PGEGPGHSASAAGAQARSTAT 476
           R H  E+P    E          R R   +L  +H R   GE P +       +  S++ 
Sbjct: 281 RTHTGEKPYTCLECNR-------RFRQRTALV-IHQRIHTGEKP-YPCPDCERRFSSSSR 331

Query: 477 QEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGT 536
              +  +  G RP          C  C   F     L  H  +HTGE+PY CP C  A  
Sbjct: 332 LVSHRRVHSGERPYA--------CEHCEARFSQRSTLLQHQLLHTGEKPYPCPDCGRAFR 383

Query: 537 QSGSLKYHLQRHHREQ 552
           +SGSL  H   H  E+
Sbjct: 384 RSGSLAIHRSTHTEEK 399



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 26/64 (40%), Positives = 34/64 (53%), Gaps = 5/64 (7%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
           CP C + F S+  L  H RVH+GERPY C HC+   +Q  +L  H   H     +G  P 
Sbjct: 319 CPDCERRFSSSSRLVSHRRVHSGERPYACEHCEARFSQRSTLLQHQLLH-----TGEKPY 373

Query: 560 PPPE 563
           P P+
Sbjct: 374 PCPD 377



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 4/76 (5%)

Query: 37  AGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQ 96
           +GSL +   + +E    E+   C  CG+RF + S+LA H R H G + + C  C  R AQ
Sbjct: 385 SGSLAIHRSTHTE----EKLHACDDCGRRFAYPSLLASHRRVHSGERPYACDLCSKRFAQ 440

Query: 97  RALLRSHLRTHQPERP 112
            + L  H   H  E+P
Sbjct: 441 WSHLAQHQLLHTGEKP 456



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 45/166 (27%), Positives = 64/166 (38%), Gaps = 24/166 (14%)

Query: 398 PGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPG 457
           P  GR F       S L +  R H  E P     V +   + +++ ++L     +H   G
Sbjct: 180 PDCGRRFS----YPSLLVSHRRAHSGECPY----VCDQCGKRFSQRKNLSQHQVIHT--G 229

Query: 458 EGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHL 517
           E P H         RS +         G  +P          CP CG+ F     L +H 
Sbjct: 230 EKPYHCPDCGRCFRRSRSLANHRTTHTG-EKPH--------QCPSCGRRFAYPSLLAIHQ 280

Query: 518 RVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPE 563
           R HTGE+PY C  C+    Q  +L  H + H     +G  P P P+
Sbjct: 281 RTHTGEKPYTCLECNRRFRQRTALVIHQRIH-----TGEKPYPCPD 321



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 22/52 (42%), Positives = 26/52 (50%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSH 103
           +GER + C +C KRF   S LA H   H G + F C  CG    QR  L  H
Sbjct: 424 SGERPYACDLCSKRFAQWSHLAQHQLLHTGEKPFPCLECGRCFRQRWSLAVH 475


>gi|24432013 zinc finger protein 668 [Homo sapiens]
          Length = 619

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 139/591 (23%), Positives = 205/591 (34%), Gaps = 104/591 (17%)

Query: 6   PRAPSG--HLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCPVCG 63
           P AP    H A   PA D   ++      P   A +        S S A  R + CP+C 
Sbjct: 32  PNAPRAARHAATHGPA-DCSEEVAEVKPKPETEAKAEEASGEKVSGSAAKPRPYACPLCP 90

Query: 64  KRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPER-------PRSPA 116
           K ++    L  H R+H G + F CP CG R  Q   LR HL +H  E        P++  
Sbjct: 91  KAYKTAPELRSHGRSHTGEKPFPCPECGRRFMQPVCLRVHLASHAGELPFRCAHCPKAYG 150

Query: 117 ARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSA 176
           A   L++ +R    E                      RP A       C  C   F   +
Sbjct: 151 ALSKLKIHQRGHTGE----------------------RPYA-------CADCGKSFADPS 181

Query: 177 --ERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQP 234
              + R  H   RP+ C  C    ++ ++L +H  +  G  ERP   +            
Sbjct: 182 VFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTG--ERPFLCSECGKSFSRSSSL 239

Query: 235 PPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPE-FRCQVCGQSFTQSWFLKGHM 293
                  +  +P   P   +  T   +  + E   +  + F C  CG+ F+     + H 
Sbjct: 240 TCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQ 299

Query: 294 RKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLA 353
           R H+    + C  CG+ F++P  L  H +VH               P +  Q     + +
Sbjct: 300 RAHEEVKPYHCEKCGKDFRQPADLAMHRRVHT-----------GDRPFKCLQCDKTFVAS 348

Query: 354 YEPLGPALL-LAPAPTPAER-----REPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGF 407
           ++    AL+     P   E       E  SL  +  + +GE RP    A    G+SF   
Sbjct: 349 WDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVHSGE-RPFHCNA---CGKSF--- 401

Query: 408 RPLSSALPARARRHRAEE----PEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGH- 462
             +SS+L    R HR+ E    P  +E VV         G S     S  P  G G G  
Sbjct: 402 -VVSSSLRKHERTHRSSEAAGVPPAQELVVGLALPVGVAGES-----SAAPAAGAGLGDP 455

Query: 463 SASAAGAQARSTATQEENGLLVGGT---------------RPEGGRGATGKD-------- 499
            A   G    S         +VG T                P  G G  G +        
Sbjct: 456 PAGLLGLPPESGGVMATQWQVVGMTVEHVECQDAGVREAPGPLEGAGEAGGEEADEKPPQ 515

Query: 500 --CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH 548
             C  C ++F +   L+ H R H   RP+ C  C  + +    L+ H + H
Sbjct: 516 FVCRECKETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTH 566



 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 90/354 (25%), Positives = 121/354 (34%), Gaps = 79/354 (22%)

Query: 50  SRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQP 109
           S  GER F C  CGK F  +S L  H R H   + ++CP CG    Q +  +SH RTH  
Sbjct: 217 SHTGERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSG 276

Query: 110 ERP-------RSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSA 162
           E+P       R  +        +RA   E +       G     PA   + R        
Sbjct: 277 EKPFLCPRCGRMFSDPSSFRRHQRA-HEEVKPYHCEKCGKDFRQPADLAMHRRVHTGDRP 335

Query: 163 FRCPYCKGKFRTSAERERH------------------------------LHILHRPWKCG 192
           F+C  C   F  S + +RH                              +H   RP+ C 
Sbjct: 336 FKCLQCDKTFVASWDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVHSGERPFHCN 395

Query: 193 LC--SF---GSSQEEELLHHSLTAHGAP--------------------ERPLAATSAAPP 227
            C  SF    S ++ E  H S  A G P                      P A      P
Sbjct: 396 ACGKSFVVSSSLRKHERTHRSSEAAGVPPAQELVVGLALPVGVAGESSAAPAAGAGLGDP 455

Query: 228 PQPQPQPPP----------QPEPRSVPQPEPEPEPEREATPTPAPAA-----PEEPPAPP 272
           P      PP          Q    +V   E +    REA P P   A      E    PP
Sbjct: 456 PAGLLGLPPESGGVMATQWQVVGMTVEHVECQDAGVREA-PGPLEGAGEAGGEEADEKPP 514

Query: 273 EFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHAS 326
           +F C+ C ++F+    L+ H R H       C  CG+ F +   L+ H + H+S
Sbjct: 515 QFVCRECKETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHSS 568



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 123/532 (23%), Positives = 180/532 (33%), Gaps = 75/532 (14%)

Query: 153 ARPQAP----SSSAFRCPYCKGKFRTSAERERHLHILHRPWKCG--LCSFGSSQE----- 201
           AR  AP    S   ++C  C   F  +    RH    H P  C   +       E     
Sbjct: 8   ARSPAPGYKRSGRRYKCLSCTKTFPNAPRAARHA-ATHGPADCSEEVAEVKPKPETEAKA 66

Query: 202 EELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPE---REATP 258
           EE     ++   A  RP A      P   +  P  +   RS    +P P PE   R   P
Sbjct: 67  EEASGEKVSGSAAKPRPYACPLC--PKAYKTAPELRSHGRSHTGEKPFPCPECGRRFMQP 124

Query: 259 TPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLK 318
                          FRC  C +++     LK H R H     +AC  CG+ F +P   +
Sbjct: 125 VCLRVHLASHAGELPFRCAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVFR 184

Query: 319 NHMKVHASKLGPLRAP--GPASGPARAPQPPDLGLLAYEPL-----GPALLLAPAPTPAE 371
            H + HA  L P      G A    +  +  +       P      G +   + + T  +
Sbjct: 185 KHRRTHAG-LRPYSCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCHQ 243

Query: 372 R--------REPPSLLGYLSLRAGEGRPNGEGAE-----PGPGRSFGGFRPLSSALPARA 418
           R        R P    G+  L + +        E     P  GR F          P+  
Sbjct: 244 RIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSD--------PSSF 295

Query: 419 RRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQE 478
           RRH+    E +    E   + + +   L     +H   G+ P            S   + 
Sbjct: 296 RRHQRAHEEVKPYHCEKCGKDFRQPADLAMHRRVHT--GDRPFKCLQCDKTFVASWDLKR 353

Query: 479 ENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQS 538
            + L+  G RP          C  CG++F     L  H RVH+GERP+ C  C  +   S
Sbjct: 354 -HALVHSGQRPFR--------CEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVS 404

Query: 539 GSLKYHLQRHHREQRSGAGP------GPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGAS 592
            SL+ H + H   + +G  P      G         +  +AP +GA     PA  +    
Sbjct: 405 SSLRKHERTHRSSEAAGVPPAQELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLL---- 460

Query: 593 SPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGA 644
              PP SG    ++ +    G T+ +      E  D  +R  PG   G G A
Sbjct: 461 -GLPPESGGVMATQWQVV--GMTVEH-----VECQDAGVREAPGPLEGAGEA 504



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 52/176 (29%), Positives = 65/176 (36%), Gaps = 32/176 (18%)

Query: 394 EGAEPGPGRSFGGFR----------PLSSALPARARRHRAEEPEEEEEVVEAEEETWARG 443
           E   P PG    G R          P +      A  H   +  EE   V+ + ET A+ 
Sbjct: 7   EARSPAPGYKRSGRRYKCLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKA 66

Query: 444 RSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPE---GGRGATGKD- 499
                         E  G   S + A+ R  A           T PE    GR  TG+  
Sbjct: 67  E-------------EASGEKVSGSAAKPRPYACPLCPKAYK--TAPELRSHGRSHTGEKP 111

Query: 500 --CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQR 553
             CP CG+ F     L+VHL  H GE P++C HC  A      LK H QR H  +R
Sbjct: 112 FPCPECGRRFMQPVCLRVHLASHAGELPFRCAHCPKAYGALSKLKIH-QRGHTGER 166



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 30/85 (35%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 28  RYSNGPAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQC 87
           R + GP   AG  G       E+     +F C  C + F   ++L  H R+HP  + F C
Sbjct: 492 REAPGPLEGAGEAG-----GEEADEKPPQFVCRECKETFSTMTLLRRHERSHPELRPFPC 546

Query: 88  PHCGHRAAQRALLRSHLRTHQPERP 112
             CG   + RA LR H RTH   RP
Sbjct: 547 TQCGKSFSDRAGLRKHSRTHSSVRP 571



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 54/208 (25%), Positives = 81/208 (38%), Gaps = 25/208 (12%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
           C  CGK++     L+ H R HTGERP+ C  C  + ++S SL  H QR H  Q+      
Sbjct: 198 CERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCH-QRIHAAQK------ 250

Query: 560 PPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRK------PASPG 613
             P   P   +G    S  +   +  +  +    PR     + P S R+         P 
Sbjct: 251 --PYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEEVKPY 308

Query: 614 RTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRR- 672
              + G+    +P DL++          G    +CL C     A   +  H  VH  +R 
Sbjct: 309 HCEKCGKDFR-QPADLAMHR----RVHTGDRPFKCLQCDKTFVASWDLKRHALVHSGQRP 363

Query: 673 ----ARGRRPPQADASPPYARVPSGETP 696
                 GR   +  +   ++RV SGE P
Sbjct: 364 FRCEECGRAFAERASLTKHSRVHSGERP 391



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 21/49 (42%), Positives = 26/49 (53%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRH 548
           C  CGKSF     L+ H R H+  RPY CPHC  A   +  L+ H + H
Sbjct: 546 CTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTH 594



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 22/53 (41%), Positives = 26/53 (49%)

Query: 55  RRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTH 107
           R FPC  CGK F   + L  H R H   + + CPHC       + LR H RTH
Sbjct: 542 RPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTH 594



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 60/266 (22%), Positives = 87/266 (32%), Gaps = 38/266 (14%)

Query: 85  FQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQ 144
           ++C  C            H  TH P       A +  + E  A   EA         G  
Sbjct: 22  YKCLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKAEEAS---GEKVSGSA 78

Query: 145 ATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERERH--LHILHRPWKCGLCSFGSSQEE 202
           A P      RP A       CP C   ++T+ E   H   H   +P+ C  C     Q  
Sbjct: 79  AKP------RPYA-------CPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGRRFMQPV 125

Query: 203 ELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEP---------EPEPE 253
            L  H L +H A E P              +        +  +P           +P   
Sbjct: 126 CLRVH-LASH-AGELPFRCAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVF 183

Query: 254 REATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKE 313
           R+   T A   P        + C+ CG+++ +   L+ H R H       C  CG+ F  
Sbjct: 184 RKHRRTHAGLRP--------YSCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSR 235

Query: 314 PWFLKNHMKVHASKLGPLRAPGPASG 339
              L  H ++HA++  P R P    G
Sbjct: 236 SSSLTCHQRIHAAQ-KPYRCPACGKG 260


>gi|13376064 zinc finger protein 408 [Homo sapiens]
          Length = 720

 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 72/235 (30%), Positives = 90/235 (38%), Gaps = 27/235 (11%)

Query: 58  PCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP-RSP- 115
           PCPVCG+       L  H+R H G + F CPHCG    QR  LR HLR H  ERP R P 
Sbjct: 469 PCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPH 528

Query: 116 ---AARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKF 172
              A   L EL    +            G     P T             F CP C   +
Sbjct: 529 CADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAY 588

Query: 173 RTSAERERHL--HILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQP 230
             + +  RHL  H+  +P++C  C  G +  + L  H L+    PE P      +PP  P
Sbjct: 589 TLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHR--PEAP-----CSPPSVP 641

Query: 231 QPQPPP-----QPEPRSV-PQPEPEPEPEREATPTPAP-------AAPEEPPAPP 272
                P     Q EP+ +    E E  P R+                PEEP A P
Sbjct: 642 SAASEPTVVLLQAEPQLLDTHREEEVSPARDVVEVTISESQEKCFVVPEEPDAAP 696



 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 111/416 (26%), Positives = 147/416 (35%), Gaps = 60/416 (14%)

Query: 194 CSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQP-------QPPPQPEPRSVPQP 246
           C   +    EL  +S T         + +S+A   QP          P  Q  PR+    
Sbjct: 265 CPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSPSDQCPPRA---K 321

Query: 247 EPEPEPEREATPT-----PAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFD 301
            PEP  ++   PT     P PA    P     +RC  CG++F Q   LK H   H     
Sbjct: 322 TPEPGAQQSGFPTLSRSPPGPAG-SSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKP 380

Query: 302 HACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPAL 361
             C  CG+ +      K HM  H    G    P P    A   Q  DL        G   
Sbjct: 381 FLCTECGKSYSSEESFKAHMLGHR---GVRPFPCPQCDKAYGTQR-DLKEHQVVHSGARP 436

Query: 362 LLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSS--ALPARAR 419
                   A  R P       SLR    + +   A P P       RPL++  +L    R
Sbjct: 437 FACDQCGKAFARRP-------SLRLHR-KTHQVPAAPAPCPCPVCGRPLANQGSLRNHMR 488

Query: 420 RHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEE 479
            H  E+P        A  +   RG   G L  LH   GE P      A A  +    +  
Sbjct: 489 LHTGEKPFLCPHCGRAFRQ---RGNLRGHLR-LHT--GERPYRCPHCADAFPQLPELRRH 542

Query: 480 NGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSG 539
              L+  T            CP CGK+ R  H L+ H R+H+GERP+ CP C  A T + 
Sbjct: 543 ---LISHT-------GEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLAT 592

Query: 540 SLKYHLQRH-----HREQRSGAGPGPPP---------EPPPPSQRGSAPQSGAKPS 581
            L+ HL+ H     +R    G G   P           P  P    S P + ++P+
Sbjct: 593 KLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEAPCSPPSVPSAASEPT 648



 Score = 79.7 bits (195), Expect = 9e-15
 Identities = 78/323 (24%), Positives = 109/323 (33%), Gaps = 62/323 (19%)

Query: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP 112
           G + F C  CGK +        H+  H G + F CP C      +  L+ H   H   RP
Sbjct: 377 GHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARP 436

Query: 113 RSPAARLLLELEERALLREARLGRARSSGGMQATPA---TEGLARPQAPSSS-------- 161
                    +   +A  R   L   R +  + A PA        RP A   S        
Sbjct: 437 ------FACDQCGKAFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLH 490

Query: 162 ----AFRCPYCKGKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAP 215
                F CP+C   FR       H  LH   RP++C  C+    Q  EL  H ++  G  
Sbjct: 491 TGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEA 550

Query: 216 ERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFR 275
                   A              +P ++   E     ER                   F 
Sbjct: 551 HLCPVCGKAL------------RDPHTLRAHERLHSGER------------------PFP 580

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPG 335
           C  CG+++T +  L+ H++ H     + CP CG  +  P  L+ H   H       R   
Sbjct: 581 CPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSH-------RPEA 633

Query: 336 PASGPA--RAPQPPDLGLLAYEP 356
           P S P+   A   P + LL  EP
Sbjct: 634 PCSPPSVPSAASEPTVVLLQAEP 656



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 74/296 (25%), Positives = 107/296 (36%), Gaps = 22/296 (7%)

Query: 137 ARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERERH--LHILHRPWKCGLC 194
           A+ SG    + +  G A         +RC  C   F      ++H  +H  H+P+ C  C
Sbjct: 327 AQQSGFPTLSRSPPGPAGSSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTEC 386

Query: 195 SFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPER 254
               S EE    H L   G   RP            Q          S  +P    +  +
Sbjct: 387 GKSYSSEESFKAHMLGHRGV--RPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGK 444

Query: 255 EATPTPA----PAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRC 310
                P+        + P AP    C VCG+       L+ HMR H       CP CGR 
Sbjct: 445 AFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRA 504

Query: 311 FKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPA 370
           F++   L+ H+++H  +  P R P  A      PQ P+L        G A  L P    A
Sbjct: 505 FRQRGNLRGHLRLHTGE-RPYRCPHCADA---FPQLPELRRHLISHTGEA-HLCPVCGKA 559

Query: 371 ERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEP 426
             R+P +L  +  L +GE         P P    G    L++ L    + H  ++P
Sbjct: 560 -LRDPHTLRAHERLHSGE--------RPFPCPQCGRAYTLATKLRRHLKSHLEDKP 606



 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 35/85 (41%), Positives = 44/85 (51%)

Query: 500 CPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPG 559
           CP CG++FR   +L+ HLR+HTGERPY+CPHC  A  Q   L+ HL  H  E       G
Sbjct: 498 CPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCG 557

Query: 560 PPPEPPPPSQRGSAPQSGAKPSPQP 584
                P   +      SG +P P P
Sbjct: 558 KALRDPHTLRAHERLHSGERPFPCP 582



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 85/342 (24%), Positives = 120/342 (35%), Gaps = 52/342 (15%)

Query: 234 PPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHM 293
           P P  E  S+ QP  + E           A  +E  +P E   + C    +QS    G  
Sbjct: 171 PQPSSEGPSLTQPGLDKEAAVAVVTEVESAVQQEVASPGEDAAEPCIDPGSQS--PSGIQ 228

Query: 294 RKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASG--PARAPQPPDLGL 351
            ++  S     P   R  K+           +  LGPL   G      PA+A  PP+L  
Sbjct: 229 AENMVSPGLKFPTQDRISKD-----------SQPLGPLLQDGDVDEECPAQAQMPPELQS 277

Query: 352 LAYEPLGPALLLAPAPTPAERREPPSLLGYLS--LRAGEGRPNGEGAEPGPGRSFGGFRP 409
            +     P    A   + A   +P    GYL+  L +   +       P PG    GF  
Sbjct: 278 NSATQQDPDGSGASFSSSARGTQPH---GYLAKKLHSPSDQCPPRAKTPEPGAQQSGFPT 334

Query: 410 LSSALPARA-------RRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGH 462
           LS + P  A       RR+R  E                 G++   L  L        GH
Sbjct: 335 LSRSPPGPAGSSPKQGRRYRCGEC----------------GKAFLQLCHLKKHAFVHTGH 378

Query: 463 SASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTG 522
                    +S +++E            G RG     CP C K++ +   LK H  VH+G
Sbjct: 379 KPFLCTECGKSYSSEESFK-----AHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSG 433

Query: 523 ERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEP 564
            RP+ C  C  A  +  SL+ H + H    +  A P P P P
Sbjct: 434 ARPFACDQCGKAFARRPSLRLHRKTH----QVPAAPAPCPCP 471



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 26/64 (40%), Positives = 37/64 (57%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPER 111
           +GER FPCP CG+ +   + L  HL++H   + ++CP CG        LR H  +H+PE 
Sbjct: 574 SGERPFPCPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEA 633

Query: 112 PRSP 115
           P SP
Sbjct: 634 PCSP 637


>gi|221307573 zinc finger protein 275 [Homo sapiens]
          Length = 429

 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 75/276 (27%), Positives = 104/276 (37%), Gaps = 37/276 (13%)

Query: 57  FPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPA 116
           F C  CGKRF+ N+ L+ HLR H   + F C  CG        L  H + H  E+P +  
Sbjct: 181 FECEECGKRFKKNAGLSQHLRVHSREKPFDCEECGRSFKVNTHLFRHQKLHTSEKPFACK 240

Query: 117 ARLLLELEERALLREARLGRAR----SSGGMQATPATEGLARPQAPSSSA--FRCPYCKG 170
           A     L+ + LL+  R+             ++     GLA  Q   S A  + CP+C  
Sbjct: 241 ACSRDFLDRQELLKHQRMHTGHLPFDCDDCGKSFRGVNGLAEHQRIHSGAKPYGCPHCGK 300

Query: 171 KFRTSAE--RERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPP 228
            FR S+E  + R +H   +P+ CG C     Q   LL H+    G  ERP A        
Sbjct: 301 LFRRSSELTKHRRIHTGEKPYACGQCGKAFRQSSSLLEHARIHSG--ERPYACGECGKAF 358

Query: 229 QPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWF 288
           +            S  +P                           + C  CG++F +S  
Sbjct: 359 RGPSDLIKHRRIHSGLKP---------------------------YECDKCGKAFRRSSG 391

Query: 289 LKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVH 324
           L  H R H  +    C  CGR FK    L+ H   H
Sbjct: 392 LSRHRRIHSGARRCECSQCGRVFKRRSALQKHQPTH 427



 Score = 80.1 bits (196), Expect = 7e-15
 Identities = 72/288 (25%), Positives = 105/288 (36%), Gaps = 29/288 (10%)

Query: 54  ERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPR 113
           E  F C  CG  FR   +L  H R H   + ++C  CG      A    H ++H    P+
Sbjct: 98  EHHFACKECGDTFRLKVLLVQHQRVHSEEKGWECGDCGKVFRGVAEFNEHRKSHVAAEPQ 157

Query: 114 SPAARLLLELEER--ALLREARLGRARSSGGMQATPATEGLARPQAPSS--SAFRCPYCK 169
              +R L    E+   + REA+       G  +      GL++     S    F C  C 
Sbjct: 158 PGPSRALENAAEKREQMEREAKPFECEECG--KRFKKNAGLSQHLRVHSREKPFDCEECG 215

Query: 170 GKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHHSL--TAH--------GAPER 217
             F+ +    RH  LH   +P+ C  CS      +ELL H    T H        G   R
Sbjct: 216 RSFKVNTHLFRHQKLHTSEKPFACKACSRDFLDRQELLKHQRMHTGHLPFDCDDCGKSFR 275

Query: 218 PLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQ 277
            +   +         +P   P    + +   E    R       P           + C 
Sbjct: 276 GVNGLAEHQRIHSGAKPYGCPHCGKLFRRSSELTKHRRIHTGEKP-----------YACG 324

Query: 278 VCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHA 325
            CG++F QS  L  H R H     +AC  CG+ F+ P  L  H ++H+
Sbjct: 325 QCGKAFRQSSSLLEHARIHSGERPYACGECGKAFRGPSDLIKHRRIHS 372



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 100/407 (24%), Positives = 132/407 (32%), Gaps = 79/407 (19%)

Query: 199 SQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPE---PEPEPERE 255
           +Q + LL    + +  P +   +TSA           PQ E  S   P    P PE  + 
Sbjct: 24  AQGQVLLVSDPSPNTDPAKYSESTSATRHQMKGEDAQPQ-EMASTSFPRASGPSPEFRQH 82

Query: 256 ATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPW 315
                   +P+  P    F C+ CG +F     L  H R H       C  CG+ F+   
Sbjct: 83  GDSDGKRGSPQNLPIEHHFACKECGDTFRLKVLLVQHQRVHSEEKGWECGDCGKVFRGVA 142

Query: 316 FLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREP 375
               H K H                A  PQP           GP+  L  A   AE+RE 
Sbjct: 143 EFNEHRKSHV---------------AAEPQP-----------GPSRALENA---AEKREQ 173

Query: 376 PSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEV--- 432
                               A+P      G     ++ L    R H  E+P + EE    
Sbjct: 174 ME----------------REAKPFECEECGKRFKKNAGLSQHLRVHSREKPFDCEECGRS 217

Query: 433 ------------VEAEEETWAR---GRSLGSLASLHPRPGEGPGH---SASAAGAQARST 474
                       +   E+ +A     R       L        GH        G   R  
Sbjct: 218 FKVNTHLFRHQKLHTSEKPFACKACSRDFLDRQELLKHQRMHTGHLPFDCDDCGKSFRGV 277

Query: 475 ATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYA 534
               E+  +  G +P G        CP CGK FR +  L  H R+HTGE+PY C  C  A
Sbjct: 278 NGLAEHQRIHSGAKPYG--------CPHCGKLFRRSSELTKHRRIHTGEKPYACGQCGKA 329

Query: 535 GTQSGSLKYHLQRHHREQRSGAGP-GPPPEPPPPSQRGSAPQSGAKP 580
             QS SL  H + H  E+    G  G     P    +     SG KP
Sbjct: 330 FRQSSSLLEHARIHSGERPYACGECGKAFRGPSDLIKHRRIHSGLKP 376



 Score = 75.9 bits (185), Expect = 1e-13
 Identities = 98/395 (24%), Positives = 141/395 (35%), Gaps = 65/395 (16%)

Query: 158 PSSSAFRCPYCKGKFRTSAERERH--LHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAP 215
           P    F C  C   FR      +H  +H   + W+CG C        E   H   +H A 
Sbjct: 96  PIEHHFACKECGDTFRLKVLLVQHQRVHSEEKGWECGDCGKVFRGVAEFNEHR-KSHVAA 154

Query: 216 ERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFR 275
           E             PQP P    E  +    E   + EREA P               F 
Sbjct: 155 E-------------PQPGPSRALENAA----EKREQMEREAKP---------------FE 182

Query: 276 CQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPG 335
           C+ CG+ F ++  L  H+R H       C  CGR FK    L  H K+H S+      P 
Sbjct: 183 CEECGKRFKKNAGLSQHLRVHSREKPFDCEECGRSFKVNTHLFRHQKLHTSE-----KPF 237

Query: 336 PASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERRE-PPSLLGYLSLRAGEGRPNGE 394
                +R         L  + L     +     P +  +   S  G   L   E +    
Sbjct: 238 ACKACSR-------DFLDRQELLKHQRMHTGHLPFDCDDCGKSFRGVNGL--AEHQRIHS 288

Query: 395 GAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHP 454
           GA+P      G     SS L    R H  E+P    +  +A    + +  SL   A +H 
Sbjct: 289 GAKPYGCPHCGKLFRRSSELTKHRRIHTGEKPYACGQCGKA----FRQSSSLLEHARIHS 344

Query: 455 RPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLK 514
             GE P ++    G   R  +   ++  +  G +P         +C  CGK+FR +  L 
Sbjct: 345 --GERP-YACGECGKAFRGPSDLIKHRRIHSGLKPY--------ECDKCGKAFRRSSGLS 393

Query: 515 VHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHH 549
            H R+H+G R  +C  C     +  +L+ H   HH
Sbjct: 394 RHRRIHSGARRCECSQCGRVFKRRSALQKHQPTHH 428



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 49/168 (29%), Positives = 66/168 (39%), Gaps = 8/168 (4%)

Query: 53  GERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERP 112
           G   F C  CGK FR  + LA H R H GA+ + CPHCG    + + L  H R H  E+P
Sbjct: 261 GHLPFDCDDCGKSFRGVNGLAEHQRIHSGAKPYGCPHCGKLFRRSSELTKHRRIHTGEKP 320

Query: 113 RS-----PAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSS-SAFRCP 166
            +      A R    L E A +       A    G      ++ +   +  S    + C 
Sbjct: 321 YACGQCGKAFRQSSSLLEHARIHSGERPYACGECGKAFRGPSDLIKHRRIHSGLKPYECD 380

Query: 167 YCKGKFRTSA--ERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAH 212
            C   FR S+   R R +H   R  +C  C     +   L  H  T H
Sbjct: 381 KCGKAFRRSSGLSRHRRIHSGARRCECSQCGRVFKRRSALQKHQPTHH 428



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 9/97 (9%)

Query: 457 GEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVH 516
           GE P ++    G   R +++  E+  +  G RP          C  CGK+FR    L  H
Sbjct: 317 GEKP-YACGQCGKAFRQSSSLLEHARIHSGERPYA--------CGECGKAFRGPSDLIKH 367

Query: 517 LRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQR 553
            R+H+G +PY+C  C  A  +S  L  H + H   +R
Sbjct: 368 RRIHSGLKPYECDKCGKAFRRSSGLSRHRRIHSGARR 404



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 22/56 (39%), Positives = 32/56 (57%)

Query: 52  AGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTH 107
           +G + + C  CGK FR +S L+ H R H GA+  +C  CG    +R+ L+ H  TH
Sbjct: 372 SGLKPYECDKCGKAFRRSSGLSRHRRIHSGARRCECSQCGRVFKRRSALQKHQPTH 427



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 26/83 (31%), Positives = 36/83 (43%)

Query: 29  YSNGPAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCP 88
           Y+ G    A       +  +   +GER + C  CGK FR  S L  H R H G + ++C 
Sbjct: 321 YACGQCGKAFRQSSSLLEHARIHSGERPYACGECGKAFRGPSDLIKHRRIHSGLKPYECD 380

Query: 89  HCGHRAAQRALLRSHLRTHQPER 111
            CG    + + L  H R H   R
Sbjct: 381 KCGKAFRRSSGLSRHRRIHSGAR 403


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,191,202
Number of Sequences: 37866
Number of extensions: 3493145
Number of successful extensions: 115590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2035
Number of HSP's successfully gapped in prelim test: 1698
Number of HSP's that attempted gapping in prelim test: 24817
Number of HSP's gapped (non-prelim): 61483
length of query: 722
length of database: 18,247,518
effective HSP length: 110
effective length of query: 612
effective length of database: 14,082,258
effective search space: 8618341896
effective search space used: 8618341896
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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