BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|156151420 hexokinase domain containing 1 [Homo sapiens] (917 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|156151420 hexokinase domain containing 1 [Homo sapiens] 1821 0.0 gi|188497754 hexokinase 1 isoform HKI [Homo sapiens] 1351 0.0 gi|15991829 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] 1323 0.0 gi|15991831 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] 1323 0.0 gi|188497750 hexokinase 1 isoform HKI-td [Homo sapiens] 1323 0.0 gi|15991827 hexokinase 1 isoform HKI-R [Homo sapiens] 1323 0.0 gi|15553127 hexokinase 2 [Homo sapiens] 1308 0.0 gi|194097330 hexokinase 3 [Homo sapiens] 950 0.0 gi|4503951 glucokinase isoform 1 [Homo sapiens] 495 e-140 gi|15967161 glucokinase isoform 3 [Homo sapiens] 494 e-139 gi|15967159 glucokinase isoform 2 [Homo sapiens] 493 e-139 gi|164663810 ribosomal modification protein rimK-like family mem... 33 1.2 gi|65301164 very low density lipoprotein receptor isoform b [Hom... 32 2.1 gi|65301167 very low density lipoprotein receptor isoform a [Hom... 32 2.1 gi|30425438 OAF homolog [Homo sapiens] 32 3.5 gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 31 4.6 gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 31 4.6 gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 31 6.0 gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 31 6.0 gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 30 7.9 gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 30 7.9 gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 30 7.9 gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 30 7.9 gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 30 7.9 >gi|156151420 hexokinase domain containing 1 [Homo sapiens] Length = 917 Score = 1821 bits (4718), Expect = 0.0 Identities = 917/917 (100%), Positives = 917/917 (100%) Query: 1 MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA 60 MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA Sbjct: 1 MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA 60 Query: 61 VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR 120 VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR Sbjct: 61 VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR 120 Query: 121 GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV 180 GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV Sbjct: 121 GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV 180 Query: 181 QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME 240 QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME Sbjct: 181 QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME 240 Query: 241 DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL 300 DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL Sbjct: 241 DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL 300 Query: 301 YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG 360 YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG Sbjct: 301 YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG 360 Query: 361 LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH 420 LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH Sbjct: 361 LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH 420 Query: 421 PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT 480 PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT Sbjct: 421 PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT 480 Query: 481 REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV 540 REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV Sbjct: 481 REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV 540 Query: 541 LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT 600 LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT Sbjct: 541 LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT 600 Query: 601 FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT 660 FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT Sbjct: 601 FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT 660 Query: 661 MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI 720 MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI Sbjct: 661 MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI 720 Query: 721 RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI 780 RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI Sbjct: 721 RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI 780 Query: 781 FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI 840 FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI Sbjct: 781 FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI 840 Query: 841 VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA 900 VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA Sbjct: 841 VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA 900 Query: 901 ALITAVAKRLQQAQKEN 917 ALITAVAKRLQQAQKEN Sbjct: 901 ALITAVAKRLQQAQKEN 917 >gi|188497754 hexokinase 1 isoform HKI [Homo sapiens] Length = 917 Score = 1351 bits (3496), Expect = 0.0 Identities = 651/912 (71%), Positives = 782/912 (85%), Gaps = 1/912 (0%) Query: 1 MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA 60 M A L+A+YF++LK+DQ+KK+D++LY MRLSD+TL+DIM RFR EM+ GL++D NPTA Sbjct: 1 MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTAT 60 Query: 61 VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR 120 VKMLPTFVR+IPDGSE G+F++LDLGGS FR+L+VQV E ++V MES+ Y TP I+ Sbjct: 61 VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVH 120 Query: 121 GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV 180 G+G++LF++VA+CL DFM+ + +K KKLP+G TFSFPC+Q+K++E +L++WTK+FKA GV Sbjct: 121 GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGV 180 Query: 181 QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME 240 + DVV L KA+++ D D +I+A+VNDTVGTMMTC YDD +CEVG+IIGTGTNACYME Sbjct: 181 EGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME 240 Query: 241 DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL 300 ++ +IDLVEGDEGRMCINTEWGAFGDDG+LEDIRTEFDRE+D GSLNPGKQLFEKM+SG+ Sbjct: 241 ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM 300 Query: 301 YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG 360 YLGELVRLIL+KMAK GLLF G + L T+GK T V+A+EK KEGL N +EIL LG Sbjct: 301 YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG 360 Query: 361 LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH 420 +EPS+ DC++VQHVCTIVSFRSANL AA L AIL RLR+NK RLRTTVG+DG+LYK H Sbjct: 361 VEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH 420 Query: 421 PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT 480 PQY +R HK +R+LVP DVRFLLSESGS KGAAMVTAVA R+ Q +QI+ LA F LT Sbjct: 421 PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT 480 Query: 481 REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV 540 ++ L++V+ +MRAE+E GL+K++H A V+MLP++V PDGTE G FLALDLGGTNFRV Sbjct: 481 KDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRV 540 Query: 541 LLVKIRSG-RRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGF 599 LLVKIRSG +R+V M+NKI+AIP+EIMQGTGEELFDHIV CI+DFLDYMG+KG +PLGF Sbjct: 541 LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF 600 Query: 600 TFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVG 659 TFSFPC+Q S+D G LI WTKGFKATDC G DVV +LR+AIKRR EFDLD+VAVVNDTVG Sbjct: 601 TFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVG 660 Query: 660 TMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDD 719 TMMTC YE+P CE+GLI GTGSN CYME+M+N+EMVEG +G+MCIN EWG FGDNGC+DD Sbjct: 661 TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDD 720 Query: 720 IRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRG 779 IRT YD VDE SLN GKQRYEKM SGMYLGEIVR ILID TK+G LFRGQISE L+TRG Sbjct: 721 IRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG 780 Query: 780 IFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAA 839 IFETKFLSQIESDRLALLQVR ILQQLGL+STC+DSI+VK VCG VSRRAAQLCGAG+AA Sbjct: 781 IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAA 840 Query: 840 IVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKG 899 +V+K RE++GL+ L +TVGVDGTLYKLHPHFSRI+ +TVKEL+P+C+V+F+LSEDGSGKG Sbjct: 841 VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG 900 Query: 900 AALITAVAKRLQ 911 AALITAV RL+ Sbjct: 901 AALITAVGVRLR 912 Score = 498 bits (1282), Expect = e-140 Identities = 235/450 (52%), Positives = 332/450 (73%) Query: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76 +Q ++++ L H L+ D LL++ +R RAEME GL K T+ A VKMLP+FVR PDG+E Sbjct: 465 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 524 Query: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136 NG+FL+LDLGG+ FRVL V++ KR V+M ++ Y P EI++G G ELF+++ C++D Sbjct: 525 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 584 Query: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196 F+ +K ++PLG TFSFPC+QT L+ G+L++WTK FKA DVV+ L A++R Sbjct: 585 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 644 Query: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMC 256 ++ D+D++A+VNDTVGTMMTCAY++P CEVG+I+GTG+NACYME+M N+++VEGD+G+MC Sbjct: 645 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 704 Query: 257 INTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKA 316 IN EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKMISG+YLGE+VR IL+ K Sbjct: 705 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 764 Query: 317 GLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCT 376 G LF G+ S L T+G ET+ ++ +E + L R IL LGL + D I V+ VC Sbjct: 765 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 824 Query: 377 IVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVP 436 +VS R+A LC A +AA++ ++REN+ ++RL TVG+DGTLYK+HP + + +H+ V++L P Sbjct: 825 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 884 Query: 437 SCDVRFLLSESGSTKGAAMVTAVASRVQAQ 466 C+V FLLSE GS KGAA++TAV R++ + Sbjct: 885 KCNVSFLLSEDGSGKGAALITAVGVRLRTE 914 Score = 496 bits (1278), Expect = e-140 Identities = 236/452 (52%), Positives = 333/452 (73%), Gaps = 1/452 (0%) Query: 466 QRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEK 525 Q K+ID+ L +L+ E L+D+ + R E++ GL + + ATV+MLPT+V +PDG+EK Sbjct: 18 QVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEK 77 Query: 526 GKFLALDLGGTNFRVLLVKIRSGR-RSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADF 584 G F+ALDLGG++FR+L V++ + ++V M ++++ P I+ G+G +LFDH+ +C+ DF Sbjct: 78 GDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDF 137 Query: 585 LDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRN 644 ++ +K LP+GFTFSFPC+Q ID+ LI WTK FKA+ EG DVV +L +AIK+R Sbjct: 138 MEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRG 197 Query: 645 EFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCI 704 ++D +IVAVVNDTVGTMMTCGY+D +CE+GLI GTG+N CYME++R+I++VEG EG+MCI Sbjct: 198 DYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCI 257 Query: 705 NTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQG 764 NTEWG FGD+G ++DIRT +D E+D GSLNPGKQ +EKM SGMYLGE+VR IL+ + K+G Sbjct: 258 NTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEG 317 Query: 765 LLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGA 824 LLF G+I+ L TRG F T +S IE ++ L + IL +LG++ + +D + V+ VC Sbjct: 318 LLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTI 377 Query: 825 VSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPR 884 VS R+A L A L AI+ + R+++G LR TVGVDG+LYK HP +SR +T++ L P Sbjct: 378 VSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPD 437 Query: 885 CDVTFMLSEDGSGKGAALITAVAKRLQQAQKE 916 DV F+LSE GSGKGAA++TAVA RL + ++ Sbjct: 438 SDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQ 469 >gi|15991829 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] Length = 921 Score = 1323 bits (3425), Expect = 0.0 Identities = 639/892 (71%), Positives = 765/892 (85%), Gaps = 1/892 (0%) Query: 21 KVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEF 80 ++D++LY MRLSD+TL+DIM RFR EM+ GL++D NPTA VKMLPTFVR+IPDGSE G+F Sbjct: 25 EIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDF 84 Query: 81 LSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKT 140 ++LDLGGS FR+L+VQV E ++V MES+ Y TP I+ G+G++LF++VA+CL DFM+ Sbjct: 85 IALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEK 144 Query: 141 KDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMD 200 + +K KKLP+G TFSFPC+Q+K++E +L++WTK+FKA GV+ DVV L KA+++ D D Sbjct: 145 RKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYD 204 Query: 201 VDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTE 260 +I+A+VNDTVGTMMTC YDD +CEVG+IIGTGTNACYME++ +IDLVEGDEGRMCINTE Sbjct: 205 ANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTE 264 Query: 261 WGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLF 320 WGAFGDDG+LEDIRTEFDRE+D GSLNPGKQLFEKM+SG+YLGELVRLIL+KMAK GLLF Sbjct: 265 WGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLF 324 Query: 321 GGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSF 380 G + L T+GK T V+A+EK KEGL N +EIL LG+EPS+ DC++VQHVCTIVSF Sbjct: 325 EGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSF 384 Query: 381 RSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDV 440 RSANL AA L AIL RLR+NK RLRTTVG+DG+LYK HPQY +R HK +R+LVP DV Sbjct: 385 RSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDV 444 Query: 441 RFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLK 500 RFLLSESGS KGAAMVTAVA R+ Q +QI+ LA F LT++ L++V+ +MRAE+E GL+ Sbjct: 445 RFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLR 504 Query: 501 KKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSG-RRSVRMYNKIF 559 K++H A V+MLP++V PDGTE G FLALDLGGTNFRVLLVKIRSG +R+V M+NKI+ Sbjct: 505 KQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIY 564 Query: 560 AIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWT 619 AIP+EIMQGTGEELFDHIV CI+DFLDYMG+KG +PLGFTFSFPC+Q S+D G LI WT Sbjct: 565 AIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWT 624 Query: 620 KGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGT 679 KGFKATDC G DVV +LR+AIKRR EFDLD+VAVVNDTVGTMMTC YE+P CE+GLI GT Sbjct: 625 KGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGT 684 Query: 680 GSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQR 739 GSN CYME+M+N+EMVEG +G+MCIN EWG FGDNGC+DDIRT YD VDE SLN GKQR Sbjct: 685 GSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQR 744 Query: 740 YEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQV 799 YEKM SGMYLGEIVR ILID TK+G LFRGQISE L+TRGIFETKFLSQIESDRLALLQV Sbjct: 745 YEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQV 804 Query: 800 RRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGV 859 R ILQQLGL+STC+DSI+VK VCG VSRRAAQLCGAG+AA+V+K RE++GL+ L +TVGV Sbjct: 805 RAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGV 864 Query: 860 DGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQ 911 DGTLYKLHPHFSRI+ +TVKEL+P+C+V+F+LSEDGSGKGAALITAV RL+ Sbjct: 865 DGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 916 Score = 498 bits (1282), Expect = e-140 Identities = 235/450 (52%), Positives = 332/450 (73%) Query: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76 +Q ++++ L H L+ D LL++ +R RAEME GL K T+ A VKMLP+FVR PDG+E Sbjct: 469 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 528 Query: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136 NG+FL+LDLGG+ FRVL V++ KR V+M ++ Y P EI++G G ELF+++ C++D Sbjct: 529 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 588 Query: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196 F+ +K ++PLG TFSFPC+QT L+ G+L++WTK FKA DVV+ L A++R Sbjct: 589 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 648 Query: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMC 256 ++ D+D++A+VNDTVGTMMTCAY++P CEVG+I+GTG+NACYME+M N+++VEGD+G+MC Sbjct: 649 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 708 Query: 257 INTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKA 316 IN EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKMISG+YLGE+VR IL+ K Sbjct: 709 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 768 Query: 317 GLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCT 376 G LF G+ S L T+G ET+ ++ +E + L R IL LGL + D I V+ VC Sbjct: 769 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 828 Query: 377 IVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVP 436 +VS R+A LC A +AA++ ++REN+ ++RL TVG+DGTLYK+HP + + +H+ V++L P Sbjct: 829 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 888 Query: 437 SCDVRFLLSESGSTKGAAMVTAVASRVQAQ 466 C+V FLLSE GS KGAA++TAV R++ + Sbjct: 889 KCNVSFLLSEDGSGKGAALITAVGVRLRTE 918 Score = 494 bits (1272), Expect = e-139 Identities = 234/449 (52%), Positives = 331/449 (73%), Gaps = 1/449 (0%) Query: 469 QIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKF 528 +ID+ L +L+ E L+D+ + R E++ GL + + ATV+MLPT+V +PDG+EKG F Sbjct: 25 EIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDF 84 Query: 529 LALDLGGTNFRVLLVKIRSGR-RSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDY 587 +ALDLGG++FR+L V++ + ++V M ++++ P I+ G+G +LFDH+ +C+ DF++ Sbjct: 85 IALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEK 144 Query: 588 MGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFD 647 +K LP+GFTFSFPC+Q ID+ LI WTK FKA+ EG DVV +L +AIK+R ++D Sbjct: 145 RKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYD 204 Query: 648 LDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTE 707 +IVAVVNDTVGTMMTCGY+D +CE+GLI GTG+N CYME++R+I++VEG EG+MCINTE Sbjct: 205 ANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTE 264 Query: 708 WGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLF 767 WG FGD+G ++DIRT +D E+D GSLNPGKQ +EKM SGMYLGE+VR IL+ + K+GLLF Sbjct: 265 WGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLF 324 Query: 768 RGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSR 827 G+I+ L TRG F T +S IE ++ L + IL +LG++ + +D + V+ VC VS Sbjct: 325 EGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSF 384 Query: 828 RAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDV 887 R+A L A L AI+ + R+++G LR TVGVDG+LYK HP +SR +T++ L P DV Sbjct: 385 RSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDV 444 Query: 888 TFMLSEDGSGKGAALITAVAKRLQQAQKE 916 F+LSE GSGKGAA++TAVA RL + ++ Sbjct: 445 RFLLSESGSGKGAAMVTAVAYRLAEQHRQ 473 >gi|15991831 hexokinase 1 isoform HKI-ta/tb [Homo sapiens] Length = 921 Score = 1323 bits (3425), Expect = 0.0 Identities = 639/892 (71%), Positives = 765/892 (85%), Gaps = 1/892 (0%) Query: 21 KVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEF 80 ++D++LY MRLSD+TL+DIM RFR EM+ GL++D NPTA VKMLPTFVR+IPDGSE G+F Sbjct: 25 EIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDF 84 Query: 81 LSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKT 140 ++LDLGGS FR+L+VQV E ++V MES+ Y TP I+ G+G++LF++VA+CL DFM+ Sbjct: 85 IALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEK 144 Query: 141 KDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMD 200 + +K KKLP+G TFSFPC+Q+K++E +L++WTK+FKA GV+ DVV L KA+++ D D Sbjct: 145 RKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYD 204 Query: 201 VDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTE 260 +I+A+VNDTVGTMMTC YDD +CEVG+IIGTGTNACYME++ +IDLVEGDEGRMCINTE Sbjct: 205 ANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTE 264 Query: 261 WGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLF 320 WGAFGDDG+LEDIRTEFDRE+D GSLNPGKQLFEKM+SG+YLGELVRLIL+KMAK GLLF Sbjct: 265 WGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLF 324 Query: 321 GGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSF 380 G + L T+GK T V+A+EK KEGL N +EIL LG+EPS+ DC++VQHVCTIVSF Sbjct: 325 EGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSF 384 Query: 381 RSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDV 440 RSANL AA L AIL RLR+NK RLRTTVG+DG+LYK HPQY +R HK +R+LVP DV Sbjct: 385 RSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDV 444 Query: 441 RFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLK 500 RFLLSESGS KGAAMVTAVA R+ Q +QI+ LA F LT++ L++V+ +MRAE+E GL+ Sbjct: 445 RFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLR 504 Query: 501 KKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSG-RRSVRMYNKIF 559 K++H A V+MLP++V PDGTE G FLALDLGGTNFRVLLVKIRSG +R+V M+NKI+ Sbjct: 505 KQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIY 564 Query: 560 AIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWT 619 AIP+EIMQGTGEELFDHIV CI+DFLDYMG+KG +PLGFTFSFPC+Q S+D G LI WT Sbjct: 565 AIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWT 624 Query: 620 KGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGT 679 KGFKATDC G DVV +LR+AIKRR EFDLD+VAVVNDTVGTMMTC YE+P CE+GLI GT Sbjct: 625 KGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGT 684 Query: 680 GSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQR 739 GSN CYME+M+N+EMVEG +G+MCIN EWG FGDNGC+DDIRT YD VDE SLN GKQR Sbjct: 685 GSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQR 744 Query: 740 YEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQV 799 YEKM SGMYLGEIVR ILID TK+G LFRGQISE L+TRGIFETKFLSQIESDRLALLQV Sbjct: 745 YEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQV 804 Query: 800 RRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGV 859 R ILQQLGL+STC+DSI+VK VCG VSRRAAQLCGAG+AA+V+K RE++GL+ L +TVGV Sbjct: 805 RAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGV 864 Query: 860 DGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQ 911 DGTLYKLHPHFSRI+ +TVKEL+P+C+V+F+LSEDGSGKGAALITAV RL+ Sbjct: 865 DGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 916 Score = 498 bits (1282), Expect = e-140 Identities = 235/450 (52%), Positives = 332/450 (73%) Query: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76 +Q ++++ L H L+ D LL++ +R RAEME GL K T+ A VKMLP+FVR PDG+E Sbjct: 469 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 528 Query: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136 NG+FL+LDLGG+ FRVL V++ KR V+M ++ Y P EI++G G ELF+++ C++D Sbjct: 529 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 588 Query: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196 F+ +K ++PLG TFSFPC+QT L+ G+L++WTK FKA DVV+ L A++R Sbjct: 589 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 648 Query: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMC 256 ++ D+D++A+VNDTVGTMMTCAY++P CEVG+I+GTG+NACYME+M N+++VEGD+G+MC Sbjct: 649 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 708 Query: 257 INTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKA 316 IN EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKMISG+YLGE+VR IL+ K Sbjct: 709 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 768 Query: 317 GLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCT 376 G LF G+ S L T+G ET+ ++ +E + L R IL LGL + D I V+ VC Sbjct: 769 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 828 Query: 377 IVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVP 436 +VS R+A LC A +AA++ ++REN+ ++RL TVG+DGTLYK+HP + + +H+ V++L P Sbjct: 829 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 888 Query: 437 SCDVRFLLSESGSTKGAAMVTAVASRVQAQ 466 C+V FLLSE GS KGAA++TAV R++ + Sbjct: 889 KCNVSFLLSEDGSGKGAALITAVGVRLRTE 918 Score = 494 bits (1272), Expect = e-139 Identities = 234/449 (52%), Positives = 331/449 (73%), Gaps = 1/449 (0%) Query: 469 QIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKF 528 +ID+ L +L+ E L+D+ + R E++ GL + + ATV+MLPT+V +PDG+EKG F Sbjct: 25 EIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDF 84 Query: 529 LALDLGGTNFRVLLVKIRSGR-RSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDY 587 +ALDLGG++FR+L V++ + ++V M ++++ P I+ G+G +LFDH+ +C+ DF++ Sbjct: 85 IALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEK 144 Query: 588 MGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFD 647 +K LP+GFTFSFPC+Q ID+ LI WTK FKA+ EG DVV +L +AIK+R ++D Sbjct: 145 RKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYD 204 Query: 648 LDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTE 707 +IVAVVNDTVGTMMTCGY+D +CE+GLI GTG+N CYME++R+I++VEG EG+MCINTE Sbjct: 205 ANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTE 264 Query: 708 WGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLF 767 WG FGD+G ++DIRT +D E+D GSLNPGKQ +EKM SGMYLGE+VR IL+ + K+GLLF Sbjct: 265 WGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLF 324 Query: 768 RGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSR 827 G+I+ L TRG F T +S IE ++ L + IL +LG++ + +D + V+ VC VS Sbjct: 325 EGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSF 384 Query: 828 RAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDV 887 R+A L A L AI+ + R+++G LR TVGVDG+LYK HP +SR +T++ L P DV Sbjct: 385 RSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDV 444 Query: 888 TFMLSEDGSGKGAALITAVAKRLQQAQKE 916 F+LSE GSGKGAA++TAVA RL + ++ Sbjct: 445 RFLLSESGSGKGAAMVTAVAYRLAEQHRQ 473 >gi|188497750 hexokinase 1 isoform HKI-td [Homo sapiens] Length = 905 Score = 1323 bits (3424), Expect = 0.0 Identities = 639/891 (71%), Positives = 764/891 (85%), Gaps = 1/891 (0%) Query: 22 VDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFL 81 +D++LY MRLSD+TL+DIM RFR EM+ GL++D NPTA VKMLPTFVR+IPDGSE G+F+ Sbjct: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69 Query: 82 SLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK 141 +LDLGGS FR+L+VQV E ++V MES+ Y TP I+ G+G++LF++VA+CL DFM+ + Sbjct: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129 Query: 142 DLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDV 201 +K KKLP+G TFSFPC+Q+K++E +L++WTK+FKA GV+ DVV L KA+++ D D Sbjct: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189 Query: 202 DILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEW 261 +I+A+VNDTVGTMMTC YDD +CEVG+IIGTGTNACYME++ +IDLVEGDEGRMCINTEW Sbjct: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249 Query: 262 GAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFG 321 GAFGDDG+LEDIRTEFDRE+D GSLNPGKQLFEKM+SG+YLGELVRLIL+KMAK GLLF Sbjct: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309 Query: 322 GEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSFR 381 G + L T+GK T V+A+EK KEGL N +EIL LG+EPS+ DC++VQHVCTIVSFR Sbjct: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369 Query: 382 SANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDVR 441 SANL AA L AIL RLR+NK RLRTTVG+DG+LYK HPQY +R HK +R+LVP DVR Sbjct: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429 Query: 442 FLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKK 501 FLLSESGS KGAAMVTAVA R+ Q +QI+ LA F LT++ L++V+ +MRAE+E GL+K Sbjct: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 489 Query: 502 KSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSG-RRSVRMYNKIFA 560 ++H A V+MLP++V PDGTE G FLALDLGGTNFRVLLVKIRSG +R+V M+NKI+A Sbjct: 490 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 549 Query: 561 IPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTK 620 IP+EIMQGTGEELFDHIV CI+DFLDYMG+KG +PLGFTFSFPC+Q S+D G LI WTK Sbjct: 550 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 609 Query: 621 GFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTG 680 GFKATDC G DVV +LR+AIKRR EFDLD+VAVVNDTVGTMMTC YE+P CE+GLI GTG Sbjct: 610 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 669 Query: 681 SNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRY 740 SN CYME+M+N+EMVEG +G+MCIN EWG FGDNGC+DDIRT YD VDE SLN GKQRY Sbjct: 670 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 729 Query: 741 EKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVR 800 EKM SGMYLGEIVR ILID TK+G LFRGQISE L+TRGIFETKFLSQIESDRLALLQVR Sbjct: 730 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 789 Query: 801 RILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVD 860 ILQQLGL+STC+DSI+VK VCG VSRRAAQLCGAG+AA+V+K RE++GL+ L +TVGVD Sbjct: 790 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 849 Query: 861 GTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQ 911 GTLYKLHPHFSRI+ +TVKEL+P+C+V+F+LSEDGSGKGAALITAV RL+ Sbjct: 850 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 900 Score = 498 bits (1282), Expect = e-140 Identities = 235/450 (52%), Positives = 332/450 (73%) Query: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76 +Q ++++ L H L+ D LL++ +R RAEME GL K T+ A VKMLP+FVR PDG+E Sbjct: 453 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 512 Query: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136 NG+FL+LDLGG+ FRVL V++ KR V+M ++ Y P EI++G G ELF+++ C++D Sbjct: 513 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 572 Query: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196 F+ +K ++PLG TFSFPC+QT L+ G+L++WTK FKA DVV+ L A++R Sbjct: 573 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 632 Query: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMC 256 ++ D+D++A+VNDTVGTMMTCAY++P CEVG+I+GTG+NACYME+M N+++VEGD+G+MC Sbjct: 633 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 692 Query: 257 INTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKA 316 IN EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKMISG+YLGE+VR IL+ K Sbjct: 693 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 752 Query: 317 GLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCT 376 G LF G+ S L T+G ET+ ++ +E + L R IL LGL + D I V+ VC Sbjct: 753 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 812 Query: 377 IVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVP 436 +VS R+A LC A +AA++ ++REN+ ++RL TVG+DGTLYK+HP + + +H+ V++L P Sbjct: 813 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 872 Query: 437 SCDVRFLLSESGSTKGAAMVTAVASRVQAQ 466 C+V FLLSE GS KGAA++TAV R++ + Sbjct: 873 KCNVSFLLSEDGSGKGAALITAVGVRLRTE 902 Score = 493 bits (1270), Expect = e-139 Identities = 234/448 (52%), Positives = 330/448 (73%), Gaps = 1/448 (0%) Query: 470 IDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFL 529 ID+ L +L+ E L+D+ + R E++ GL + + ATV+MLPT+V +PDG+EKG F+ Sbjct: 10 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 69 Query: 530 ALDLGGTNFRVLLVKIRSGR-RSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYM 588 ALDLGG++FR+L V++ + ++V M ++++ P I+ G+G +LFDH+ +C+ DF++ Sbjct: 70 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 129 Query: 589 GLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 648 +K LP+GFTFSFPC+Q ID+ LI WTK FKA+ EG DVV +L +AIK+R ++D Sbjct: 130 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 189 Query: 649 DIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEW 708 +IVAVVNDTVGTMMTCGY+D +CE+GLI GTG+N CYME++R+I++VEG EG+MCINTEW Sbjct: 190 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 249 Query: 709 GGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFR 768 G FGD+G ++DIRT +D E+D GSLNPGKQ +EKM SGMYLGE+VR IL+ + K+GLLF Sbjct: 250 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 309 Query: 769 GQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRR 828 G+I+ L TRG F T +S IE ++ L + IL +LG++ + +D + V+ VC VS R Sbjct: 310 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 369 Query: 829 AAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVT 888 +A L A L AI+ + R+++G LR TVGVDG+LYK HP +SR +T++ L P DV Sbjct: 370 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 429 Query: 889 FMLSEDGSGKGAALITAVAKRLQQAQKE 916 F+LSE GSGKGAA++TAVA RL + ++ Sbjct: 430 FLLSESGSGKGAAMVTAVAYRLAEQHRQ 457 >gi|15991827 hexokinase 1 isoform HKI-R [Homo sapiens] Length = 916 Score = 1323 bits (3424), Expect = 0.0 Identities = 639/891 (71%), Positives = 764/891 (85%), Gaps = 1/891 (0%) Query: 22 VDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFL 81 +D++LY MRLSD+TL+DIM RFR EM+ GL++D NPTA VKMLPTFVR+IPDGSE G+F+ Sbjct: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 Query: 82 SLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMKTK 141 +LDLGGS FR+L+VQV E ++V MES+ Y TP I+ G+G++LF++VA+CL DFM+ + Sbjct: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140 Query: 142 DLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDMDV 201 +K KKLP+G TFSFPC+Q+K++E +L++WTK+FKA GV+ DVV L KA+++ D D Sbjct: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 200 Query: 202 DILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINTEW 261 +I+A+VNDTVGTMMTC YDD +CEVG+IIGTGTNACYME++ +IDLVEGDEGRMCINTEW Sbjct: 201 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 260 Query: 262 GAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLLFG 321 GAFGDDG+LEDIRTEFDRE+D GSLNPGKQLFEKM+SG+YLGELVRLIL+KMAK GLLF Sbjct: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320 Query: 322 GEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVSFR 381 G + L T+GK T V+A+EK KEGL N +EIL LG+EPS+ DC++VQHVCTIVSFR Sbjct: 321 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 380 Query: 382 SANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCDVR 441 SANL AA L AIL RLR+NK RLRTTVG+DG+LYK HPQY +R HK +R+LVP DVR Sbjct: 381 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 440 Query: 442 FLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKK 501 FLLSESGS KGAAMVTAVA R+ Q +QI+ LA F LT++ L++V+ +MRAE+E GL+K Sbjct: 441 FLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRK 500 Query: 502 KSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSG-RRSVRMYNKIFA 560 ++H A V+MLP++V PDGTE G FLALDLGGTNFRVLLVKIRSG +R+V M+NKI+A Sbjct: 501 QTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYA 560 Query: 561 IPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTK 620 IP+EIMQGTGEELFDHIV CI+DFLDYMG+KG +PLGFTFSFPC+Q S+D G LI WTK Sbjct: 561 IPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTK 620 Query: 621 GFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTG 680 GFKATDC G DVV +LR+AIKRR EFDLD+VAVVNDTVGTMMTC YE+P CE+GLI GTG Sbjct: 621 GFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTG 680 Query: 681 SNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRY 740 SN CYME+M+N+EMVEG +G+MCIN EWG FGDNGC+DDIRT YD VDE SLN GKQRY Sbjct: 681 SNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRY 740 Query: 741 EKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVR 800 EKM SGMYLGEIVR ILID TK+G LFRGQISE L+TRGIFETKFLSQIESDRLALLQVR Sbjct: 741 EKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVR 800 Query: 801 RILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVD 860 ILQQLGL+STC+DSI+VK VCG VSRRAAQLCGAG+AA+V+K RE++GL+ L +TVGVD Sbjct: 801 AILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVD 860 Query: 861 GTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQ 911 GTLYKLHPHFSRI+ +TVKEL+P+C+V+F+LSEDGSGKGAALITAV RL+ Sbjct: 861 GTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLR 911 Score = 498 bits (1282), Expect = e-140 Identities = 235/450 (52%), Positives = 332/450 (73%) Query: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76 +Q ++++ L H L+ D LL++ +R RAEME GL K T+ A VKMLP+FVR PDG+E Sbjct: 464 EQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTE 523 Query: 77 NGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLAD 136 NG+FL+LDLGG+ FRVL V++ KR V+M ++ Y P EI++G G ELF+++ C++D Sbjct: 524 NGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISD 583 Query: 137 FMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRH 196 F+ +K ++PLG TFSFPC+QT L+ G+L++WTK FKA DVV+ L A++R Sbjct: 584 FLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRR 643 Query: 197 KDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMC 256 ++ D+D++A+VNDTVGTMMTCAY++P CEVG+I+GTG+NACYME+M N+++VEGD+G+MC Sbjct: 644 EEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMC 703 Query: 257 INTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKA 316 IN EWGAFGD+G L+DIRT +DR +D SLN GKQ +EKMISG+YLGE+VR IL+ K Sbjct: 704 INMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKK 763 Query: 317 GLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCT 376 G LF G+ S L T+G ET+ ++ +E + L R IL LGL + D I V+ VC Sbjct: 764 GFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCG 823 Query: 377 IVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVP 436 +VS R+A LC A +AA++ ++REN+ ++RL TVG+DGTLYK+HP + + +H+ V++L P Sbjct: 824 VVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSP 883 Query: 437 SCDVRFLLSESGSTKGAAMVTAVASRVQAQ 466 C+V FLLSE GS KGAA++TAV R++ + Sbjct: 884 KCNVSFLLSEDGSGKGAALITAVGVRLRTE 913 Score = 493 bits (1270), Expect = e-139 Identities = 234/448 (52%), Positives = 330/448 (73%), Gaps = 1/448 (0%) Query: 470 IDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFL 529 ID+ L +L+ E L+D+ + R E++ GL + + ATV+MLPT+V +PDG+EKG F+ Sbjct: 21 IDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFI 80 Query: 530 ALDLGGTNFRVLLVKIRSGR-RSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYM 588 ALDLGG++FR+L V++ + ++V M ++++ P I+ G+G +LFDH+ +C+ DF++ Sbjct: 81 ALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKR 140 Query: 589 GLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDL 648 +K LP+GFTFSFPC+Q ID+ LI WTK FKA+ EG DVV +L +AIK+R ++D Sbjct: 141 KIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDA 200 Query: 649 DIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEW 708 +IVAVVNDTVGTMMTCGY+D +CE+GLI GTG+N CYME++R+I++VEG EG+MCINTEW Sbjct: 201 NIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEW 260 Query: 709 GGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFR 768 G FGD+G ++DIRT +D E+D GSLNPGKQ +EKM SGMYLGE+VR IL+ + K+GLLF Sbjct: 261 GAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFE 320 Query: 769 GQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRR 828 G+I+ L TRG F T +S IE ++ L + IL +LG++ + +D + V+ VC VS R Sbjct: 321 GRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFR 380 Query: 829 AAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVT 888 +A L A L AI+ + R+++G LR TVGVDG+LYK HP +SR +T++ L P DV Sbjct: 381 SANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVR 440 Query: 889 FMLSEDGSGKGAALITAVAKRLQQAQKE 916 F+LSE GSGKGAA++TAVA RL + ++ Sbjct: 441 FLLSESGSGKGAAMVTAVAYRLAEQHRQ 468 >gi|15553127 hexokinase 2 [Homo sapiens] Length = 917 Score = 1308 bits (3385), Expect = 0.0 Identities = 621/914 (67%), Positives = 775/914 (84%), Gaps = 1/914 (0%) Query: 1 MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA 60 M A HL+A++F++L DQ++KVD++LYHMRLSD+TLL+I +RFR EMEKGL T+PTAA Sbjct: 1 MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAA 60 Query: 61 VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR 120 VKMLPTFVR+ PDG+E+GEFL+LDLGG+ FRVL V+V + G + V+ME+Q Y P +I+R Sbjct: 61 VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMR 120 Query: 121 GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV 180 G+GT+LF+++A+CLA+FM +K KKLPLG TFSFPC QTKL+E L+SWTK FK+ GV Sbjct: 121 GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV 180 Query: 181 QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME 240 + DVV+ + KA++R D D+DI+A+VNDTVGTMMTC YDD CE+G+I+GTG+NACYME Sbjct: 181 EGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME 240 Query: 241 DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL 300 +M +ID+VEGDEGRMCIN EWGAFGDDG+L DIRTEFD+E+D+GSLNPGKQLFEKMISG+ Sbjct: 241 EMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGM 300 Query: 301 YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG 360 Y+GELVRLIL+KMAK LLFGG+ S L G+ ET+ ++ +E K+G+ RE+L+ LG Sbjct: 301 YMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLG 360 Query: 361 LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH 420 L+P++ DC+A +C IVS RSA+LCAA LAA+L R++ENK ERLR+T+G+DG++YK H Sbjct: 361 LDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKH 420 Query: 421 PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT 480 P + KRLHK VR+LVP CDVRFL SE GS KGAAMVTAVA R+ Q + + L QL+ Sbjct: 421 PHFAKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLS 480 Query: 481 REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV 540 +QL++V+ +M+ E+E GL K++H A V+MLPTYVC PDGTEKG FLALDLGGTNFRV Sbjct: 481 HDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV 540 Query: 541 LLVKIRSGR-RSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGF 599 LLV++R+G+ V M+NKI+AIP E+M GTG+ELFDHIVQCIADFL+YMG+KG SLPLGF Sbjct: 541 LLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF 600 Query: 600 TFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVG 659 TFSFPC+Q S+D+ L+ WTKGFKA+ CEGEDVV +L+EAI RR EFDLD+VAVVNDTVG Sbjct: 601 TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG 660 Query: 660 TMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDD 719 TMMTCG+EDP+CE+GLI GTGSN CYME+MRN+E+VEG EG+MC+N EWG FGDNGC+DD Sbjct: 661 TMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD 720 Query: 720 IRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRG 779 RT +D VDE SLNPGKQR+EKM SGMYLGEIVR ILID TK+GLLFRG+ISERL+TRG Sbjct: 721 FRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG 780 Query: 780 IFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAA 839 IFETKFLSQIESD LALLQVR ILQ LGL+STC+DSI+VKEVC V+RRAAQLCGAG+AA Sbjct: 781 IFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA 840 Query: 840 IVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKG 899 +V++ RE++GL+ L++TVGVDGTLYKLHPHF++++ ETVK+LAP+CDV+F+ SEDGSGKG Sbjct: 841 VVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLQSEDGSGKG 900 Query: 900 AALITAVAKRLQQA 913 AALITAVA R+++A Sbjct: 901 AALITAVACRIREA 914 >gi|194097330 hexokinase 3 [Homo sapiens] Length = 923 Score = 950 bits (2456), Expect = 0.0 Identities = 483/898 (53%), Positives = 633/898 (70%), Gaps = 8/898 (0%) Query: 17 DQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSE 76 D + V L +++ L I ME+ L +P AV+MLPT+V + P G+E Sbjct: 28 DSSELVQECLQQFKVTRAQLQQIQASLLGSMEQALRGQASPAPAVRMLPTYVGSTPHGTE 87 Query: 77 NGEFLSLDLG--GSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCL 134 G+F+ L+LG G+ RVL V + V+ SQ + P E++ G G +LF++ A CL Sbjct: 88 QGDFVVLELGATGASLRVLWVTLTGIEGHRVEPRSQEFVIPQEVMLGAGQQLFDFAAHCL 147 Query: 135 ADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMR 194 ++F+ + + + L LG +FSFPC QT L+ L+SWTK F+ GV+ DVV L A+R Sbjct: 148 SEFLDAQPVNKQGLQLGFSFSFPCHQTGLDRSTLISWTKGFRCSGVEGQDVVQLLRDAIR 207 Query: 195 RHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGR 254 R ++D++A+VNDTVGTMM C CEVG+++ TGTNACYME+ ++ +++ D GR Sbjct: 208 RQGAYNIDVVAVVNDTVGTMMGCEPGVRPCEVGLVVDTGTNACYMEEARHVAVLDEDRGR 267 Query: 255 MCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMA 314 +C++ EWG+F DDGAL + T FD LD SLNPG Q FEKMI GLYLGELVRL+L +A Sbjct: 268 VCVSVEWGSFSDDGALGPVLTTFDHTLDHESLNPGAQRFEKMIGGLYLGELVRLVLAHLA 327 Query: 315 KAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHV 374 + G+LFGG S AL ++G I HVA ME G A IL DLGL P +D VQHV Sbjct: 328 RCGVLFGGCTSPALLSQGSILLEHVAEMEDPSTGAARVHAILQDLGLSPGASDVELVQHV 387 Query: 375 CTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKL 434 C V R+A LCAAALAA+L+ L+ +++ + L+ V G + + HP++ L V L Sbjct: 388 CAAVCTRAAQLCAAALAAVLSCLQHSREQQTLQVAVATGGRVCERHPRFCSVLQGTVMLL 447 Query: 435 VPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAE 494 P CDV + S G +G AMVTAVA+R+ A R+ ++ LA F+L +QL VQA+MR Sbjct: 448 APECDVSLIPSVDGGGRGVAMVTAVAARLAAHRRLLEETLAPFRLNHDQLAAVQAQMRKA 507 Query: 495 LEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRVLLVKIRSGRRSVRM 554 + GL+ ++ L RMLPT+V PDG+E+G FLALDLGGTNFRVLLV++ +G V++ Sbjct: 508 MAKGLRGEASSL---RMLPTFVRATPDGSERGDFLALDLGGTNFRVLLVRVTTG---VQI 561 Query: 555 YNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGT 614 ++I++IP + QG+G++LFDHIV CI DF GL G SLPLGFTFSFPCRQ+ +D+G Sbjct: 562 TSEIYSIPETVAQGSGQQLFDHIVDCIVDFQQKQGLSGQSLPLGFTFSFPCRQLGLDQGI 621 Query: 615 LIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIG 674 L+ WTKGFKA+DCEG+DVV +LREAI RR +L++VA+VNDTVGTMM+CGYEDP CEIG Sbjct: 622 LLNWTKGFKASDCEGQDVVSLLREAITRRQAVELNVVAIVNDTVGTMMSCGYEDPRCEIG 681 Query: 675 LIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLN 734 LI GTG+N CYME++RN+ V G G+MCIN EWG FGD+G + + TR+D VD+ S+N Sbjct: 682 LIVGTGTNACYMEELRNVAGVPGDSGRMCINMEWGAFGDDGSLAMLSTRFDASVDQASIN 741 Query: 735 PGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRL 794 PGKQR+EKM SGMYLGEIVR IL+ LT G+LFRGQ +RL+TR IF+TKFLS+IESD L Sbjct: 742 PGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQIQRLQTRDIFKTKFLSEIESDSL 801 Query: 795 ALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLR 854 AL QVR IL+ LGL T +D+++V EVC AVS+RAAQLCGAG+AA+VEK RE++GLE L Sbjct: 802 ALRQVRAILEDLGLPLTSDDALMVLEVCQAVSQRAAQLCGAGVAAVVEKIRENRGLEELA 861 Query: 855 ITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGAALITAVAKRLQQ 912 ++VGVDGTLYKLHP FS ++ TV+ELAPRC VTF+ SEDGSGKGAAL+TAVA RL Q Sbjct: 862 VSVGVDGTLYKLHPRFSSLVAATVRELAPRCVVTFLQSEDGSGKGAALVTAVACRLAQ 919 >gi|4503951 glucokinase isoform 1 [Homo sapiens] Length = 465 Score = 495 bits (1274), Expect = e-140 Identities = 236/446 (52%), Positives = 327/446 (73%), Gaps = 3/446 (0%) Query: 465 AQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTE 524 A++++++++LA FQL E L V +M+ E++ GL+ ++H A+V+MLPTYV P+G+E Sbjct: 11 AKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSE 70 Query: 525 KGKFLALDLGGTNFRVLLVKIRSGRR---SVRMYNKIFAIPLEIMQGTGEELFDHIVQCI 581 G FL+LDLGGTNFRV+LVK+ G SV+ +++++IP + M GT E LFD+I +CI Sbjct: 71 VGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECI 130 Query: 582 ADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIK 641 +DFLD +K LPLGFTFSFP R IDKG L+ WTKGFKA+ EG +VV +LR+AIK Sbjct: 131 SDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIK 190 Query: 642 RRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGK 701 RR +F++D+VA+VNDTV TM++C YED CE+G+I GTG N CYME+M+N+E+VEG EG+ Sbjct: 191 RRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGR 250 Query: 702 MCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLT 761 MC+NTEWG FGD+G +D+ YD VDE S NPG+Q YEK+ G Y+GE+VR +L+ L Sbjct: 251 MCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLV 310 Query: 762 KQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEV 821 + LLF G+ SE+LRTRG FET+F+SQ+ESD Q+ IL LGL + D +V+ Sbjct: 311 DENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRA 370 Query: 822 CGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKEL 881 C +VS RAA +C AGLA ++ + RE + + +RITVGVDG++YKLHP F +V+ L Sbjct: 371 CESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRL 430 Query: 882 APRCDVTFMLSEDGSGKGAALITAVA 907 P C++TF+ SE+GSG+GAAL++AVA Sbjct: 431 TPSCEITFIESEEGSGRGAALVSAVA 456 Score = 472 bits (1214), Expect = e-133 Identities = 222/453 (49%), Positives = 323/453 (71%), Gaps = 2/453 (0%) Query: 12 SKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAI 71 ++++ + +KV++ L +L ++ L +MRR + EM++GL +T+ A+VKMLPT+VR+ Sbjct: 6 ARMEAAKKEKVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRST 65 Query: 72 PDGSENGEFLSLDLGGSKFRVLKVQVAE--EGKRHVQMESQFYPTPNEIIRGNGTELFEY 129 P+GSE G+FLSLDLGG+ FRV+ V+V E EG+ V+ + Q Y P + + G LF+Y Sbjct: 66 PEGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDY 125 Query: 130 VADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRL 189 +++C++DF+ +KHKKLPLG TFSFP R +++G+LL+WTK FKA G + +VV L Sbjct: 126 ISECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLL 185 Query: 190 TKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVE 249 A++R D ++D++A+VNDTV TM++C Y+D CEVG+I+GTG NACYME+M N++LVE Sbjct: 186 RDAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVE 245 Query: 250 GDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLI 309 GDEGRMC+NTEWGAFGD G L++ E+DR +D S NPG+QL+EK+I G Y+GELVRL+ Sbjct: 246 GDEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLV 305 Query: 310 LLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCI 369 LL++ LLF GE S L T+G ETR V+ +E IL LGL PS DC Sbjct: 306 LLRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCD 365 Query: 370 AVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHK 429 V+ C VS R+A++C+A LA ++ R+RE++ + +R TVG+DG++YK+HP + +R H Sbjct: 366 IVRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHA 425 Query: 430 VVRKLVPSCDVRFLLSESGSTKGAAMVTAVASR 462 VR+L PSC++ F+ SE GS +GAA+V+AVA + Sbjct: 426 SVRRLTPSCEITFIESEEGSGRGAALVSAVACK 458 >gi|15967161 glucokinase isoform 3 [Homo sapiens] Length = 464 Score = 494 bits (1273), Expect = e-139 Identities = 237/450 (52%), Positives = 326/450 (72%), Gaps = 3/450 (0%) Query: 461 SRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLP 520 S++ Q++++LA FQL E L V +M+ E++ GL+ ++H A+V+MLPTYV P Sbjct: 6 SQLPQPNSQVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTP 65 Query: 521 DGTEKGKFLALDLGGTNFRVLLVKIRSGRR---SVRMYNKIFAIPLEIMQGTGEELFDHI 577 +G+E G FL+LDLGGTNFRV+LVK+ G SV+ +++++IP + M GT E LFD+I Sbjct: 66 EGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYI 125 Query: 578 VQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLR 637 +CI+DFLD +K LPLGFTFSFP R IDKG L+ WTKGFKA+ EG +VV +LR Sbjct: 126 SECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLR 185 Query: 638 EAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEG 697 +AIKRR +F++D+VA+VNDTV TM++C YED CE+G+I GTG N CYME+M+N+E+VEG Sbjct: 186 DAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG 245 Query: 698 GEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQIL 757 EG+MC+NTEWG FGD+G +D+ YD VDE S NPG+Q YEK+ G Y+GE+VR +L Sbjct: 246 DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVL 305 Query: 758 IDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIV 817 + L + LLF G+ SE+LRTRG FET+F+SQ+ESD Q+ IL LGL + D + Sbjct: 306 LRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDI 365 Query: 818 VKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQET 877 V+ C +VS RAA +C AGLA ++ + RE + + +RITVGVDG++YKLHP F + Sbjct: 366 VRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHAS 425 Query: 878 VKELAPRCDVTFMLSEDGSGKGAALITAVA 907 V+ L P C++TF+ SE+GSG+GAAL++AVA Sbjct: 426 VRRLTPSCEITFIESEEGSGRGAALVSAVA 455 Score = 469 bits (1208), Expect = e-132 Identities = 221/444 (49%), Positives = 317/444 (71%), Gaps = 2/444 (0%) Query: 21 KVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEF 80 +V++ L +L ++ L +MRR + EM++GL +T+ A+VKMLPT+VR+ P+GSE G+F Sbjct: 14 QVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDF 73 Query: 81 LSLDLGGSKFRVLKVQVAE--EGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFM 138 LSLDLGG+ FRV+ V+V E EG+ V+ + Q Y P + + G LF+Y+++C++DF+ Sbjct: 74 LSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFL 133 Query: 139 KTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKD 198 +KHKKLPLG TFSFP R +++G+LL+WTK FKA G + +VV L A++R D Sbjct: 134 DKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGD 193 Query: 199 MDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCIN 258 ++D++A+VNDTV TM++C Y+D CEVG+I+GTG NACYME+M N++LVEGDEGRMC+N Sbjct: 194 FEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVN 253 Query: 259 TEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGL 318 TEWGAFGD G L++ E+DR +D S NPG+QL+EK+I G Y+GELVRL+LL++ L Sbjct: 254 TEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENL 313 Query: 319 LFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIV 378 LF GE S L T+G ETR V+ +E IL LGL PS DC V+ C V Sbjct: 314 LFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESV 373 Query: 379 SFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSC 438 S R+A++C+A LA ++ R+RE++ + +R TVG+DG++YK+HP + +R H VR+L PSC Sbjct: 374 STRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSC 433 Query: 439 DVRFLLSESGSTKGAAMVTAVASR 462 ++ F+ SE GS +GAA+V+AVA + Sbjct: 434 EITFIESEEGSGRGAALVSAVACK 457 >gi|15967159 glucokinase isoform 2 [Homo sapiens] Length = 466 Score = 493 bits (1269), Expect = e-139 Identities = 237/450 (52%), Positives = 325/450 (72%), Gaps = 3/450 (0%) Query: 461 SRVQAQRKQIDRVLALFQLTREQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLP 520 S+ Q ++++LA FQL E L V +M+ E++ GL+ ++H A+V+MLPTYV P Sbjct: 8 SQAQTALTLVEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTP 67 Query: 521 DGTEKGKFLALDLGGTNFRVLLVKIRSGRR---SVRMYNKIFAIPLEIMQGTGEELFDHI 577 +G+E G FL+LDLGGTNFRV+LVK+ G SV+ +++++IP + M GT E LFD+I Sbjct: 68 EGSEVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYI 127 Query: 578 VQCIADFLDYMGLKGASLPLGFTFSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLR 637 +CI+DFLD +K LPLGFTFSFP R IDKG L+ WTKGFKA+ EG +VV +LR Sbjct: 128 SECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLR 187 Query: 638 EAIKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEG 697 +AIKRR +F++D+VA+VNDTV TM++C YED CE+G+I GTG N CYME+M+N+E+VEG Sbjct: 188 DAIKRRGDFEMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEG 247 Query: 698 GEGKMCINTEWGGFGDNGCIDDIRTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQIL 757 EG+MC+NTEWG FGD+G +D+ YD VDE S NPG+Q YEK+ G Y+GE+VR +L Sbjct: 248 DEGRMCVNTEWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVL 307 Query: 758 IDLTKQGLLFRGQISERLRTRGIFETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIV 817 + L + LLF G+ SE+LRTRG FET+F+SQ+ESD Q+ IL LGL + D + Sbjct: 308 LRLVDENLLFHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDI 367 Query: 818 VKEVCGAVSRRAAQLCGAGLAAIVEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQET 877 V+ C +VS RAA +C AGLA ++ + RE + + +RITVGVDG++YKLHP F + Sbjct: 368 VRRACESVSTRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHAS 427 Query: 878 VKELAPRCDVTFMLSEDGSGKGAALITAVA 907 V+ L P C++TF+ SE+GSG+GAAL++AVA Sbjct: 428 VRRLTPSCEITFIESEEGSGRGAALVSAVA 457 Score = 469 bits (1207), Expect = e-132 Identities = 221/443 (49%), Positives = 316/443 (71%), Gaps = 2/443 (0%) Query: 22 VDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAAVKMLPTFVRAIPDGSENGEFL 81 V++ L +L ++ L +MRR + EM++GL +T+ A+VKMLPT+VR+ P+GSE G+FL Sbjct: 17 VEQILAEFQLQEEDLKKVMRRMQKEMDRGLRLETHEEASVKMLPTYVRSTPEGSEVGDFL 76 Query: 82 SLDLGGSKFRVLKVQVAE--EGKRHVQMESQFYPTPNEIIRGNGTELFEYVADCLADFMK 139 SLDLGG+ FRV+ V+V E EG+ V+ + Q Y P + + G LF+Y+++C++DF+ Sbjct: 77 SLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISECISDFLD 136 Query: 140 TKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGVQDTDVVSRLTKAMRRHKDM 199 +KHKKLPLG TFSFP R +++G+LL+WTK FKA G + +VV L A++R D Sbjct: 137 KHQMKHKKLPLGFTFSFPVRHEDIDKGILLNWTKGFKASGAEGNNVVGLLRDAIKRRGDF 196 Query: 200 DVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYMEDMSNIDLVEGDEGRMCINT 259 ++D++A+VNDTV TM++C Y+D CEVG+I+GTG NACYME+M N++LVEGDEGRMC+NT Sbjct: 197 EMDVVAMVNDTVATMISCYYEDHQCEVGMIVGTGCNACYMEEMQNVELVEGDEGRMCVNT 256 Query: 260 EWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGLYLGELVRLILLKMAKAGLL 319 EWGAFGD G L++ E+DR +D S NPG+QL+EK+I G Y+GELVRL+LL++ LL Sbjct: 257 EWGAFGDSGELDEFLLEYDRLVDESSANPGQQLYEKLIGGKYMGELVRLVLLRLVDENLL 316 Query: 320 FGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLGLEPSEADCIAVQHVCTIVS 379 F GE S L T+G ETR V+ +E IL LGL PS DC V+ C VS Sbjct: 317 FHGEASEQLRTRGAFETRFVSQVESDTGDRKQIYNILSTLGLRPSTTDCDIVRRACESVS 376 Query: 380 FRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIHPQYPKRLHKVVRKLVPSCD 439 R+A++C+A LA ++ R+RE++ + +R TVG+DG++YK+HP + +R H VR+L PSC+ Sbjct: 377 TRAAHMCSAGLAGVINRMRESRSEDVMRITVGVDGSVYKLHPSFKERFHASVRRLTPSCE 436 Query: 440 VRFLLSESGSTKGAAMVTAVASR 462 + F+ SE GS +GAA+V+AVA + Sbjct: 437 ITFIESEEGSGRGAALVSAVACK 459 >gi|164663810 ribosomal modification protein rimK-like family member A [Homo sapiens] Length = 391 Score = 33.1 bits (74), Expect = 1.2 Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 27/125 (21%) Query: 577 IVQCIADFLDYMGLKGASLPLGFTFSFPCRQ---MSIDKGTLIGW------TKG------ 621 I+ CI F + L G +P+ TFS+ + ID+ +G+ T+G Sbjct: 105 ILNCINKFWTFQELAGHGVPMPDTFSYGGHEDFSKMIDEAEPLGYPVVVKSTRGHRGKAV 164 Query: 622 FKATD-------CE--GEDVVDMLREAIKRRNEFDLDIVAVVNDTVGTMMTC---GYEDP 669 F A D C DV + ++ +K + D+ +V V +G+M+ C G Sbjct: 165 FLARDKHHLSDICHLIRHDVPYLFQKYVKESHGKDIRVVVVGGQVIGSMLRCSTDGRMQS 224 Query: 670 NCEIG 674 NC +G Sbjct: 225 NCSLG 229 >gi|65301164 very low density lipoprotein receptor isoform b [Homo sapiens] Length = 845 Score = 32.3 bits (72), Expect = 2.1 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 5/92 (5%) Query: 627 CEG-EDVVDMLREA-IKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMC 684 C+G ED VD E ++ + D V V + C DP+CE G + C Sbjct: 52 CDGDEDCVDGSDEKNCVKKTCAESDFVCNNGQCVPSRWKCD-GDPDCEDG--SDESPEQC 108 Query: 685 YMEDMRNIEMVEGGEGKMCINTEWGGFGDNGC 716 +M R E+ G CI W G+N C Sbjct: 109 HMRTCRIHEISCGAHSTQCIPVSWRCDGENDC 140 >gi|65301167 very low density lipoprotein receptor isoform a [Homo sapiens] Length = 873 Score = 32.3 bits (72), Expect = 2.1 Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 5/92 (5%) Query: 627 CEG-EDVVDMLREA-IKRRNEFDLDIVAVVNDTVGTMMTCGYEDPNCEIGLIAGTGSNMC 684 C+G ED VD E ++ + D V V + C DP+CE G + C Sbjct: 52 CDGDEDCVDGSDEKNCVKKTCAESDFVCNNGQCVPSRWKCD-GDPDCEDG--SDESPEQC 108 Query: 685 YMEDMRNIEMVEGGEGKMCINTEWGGFGDNGC 716 +M R E+ G CI W G+N C Sbjct: 109 HMRTCRIHEISCGAHSTQCIPVSWRCDGENDC 140 >gi|30425438 OAF homolog [Homo sapiens] Length = 273 Score = 31.6 bits (70), Expect = 3.5 Identities = 26/78 (33%), Positives = 39/78 (50%), Gaps = 9/78 (11%) Query: 841 VEKRREDQGLEHLRITVGVD---GTLYKLHPHFSRILQETVKELAPRC-DVTFMLSEDGS 896 V + E +GLEHL + V V+ G L L PH + E V + R DV F L + Sbjct: 128 VRQAEEVRGLEHLHMDVAVNFSQGAL--LSPHLHNVCAEAVDAIYTRQEDVRFWLEQ--- 182 Query: 897 GKGAALITAVAKRLQQAQ 914 G +++ A+ K +QA+ Sbjct: 183 GVDSSVFEALPKASEQAE 200 >gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] Length = 636 Score = 31.2 bits (69), Expect = 4.6 Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 8/105 (7%) Query: 425 KRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQL 484 +RL + K P+ V+ + ESG +KG V+ R + +K +D + +L +Q+ Sbjct: 205 ERLKDLFGKFGPALSVKVMTDESGKSKGFGFVS--FERHEDAQKAVDEMNGK-ELNGKQI 261 Query: 485 VDVQAKMRAELEYGLKKKSHGLATVRM-----LPTYVCGLPDGTE 524 +A+ + E + LK+K + R+ + YV L DG + Sbjct: 262 YVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGID 306 >gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] Length = 631 Score = 31.2 bits (69), Expect = 4.6 Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 8/105 (7%) Query: 425 KRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLTREQL 484 +RL + K P+ V+ + ESG +KG V+ R + +K +D + +L +Q+ Sbjct: 205 ERLKDLFGKFGPALSVKVMTDESGKSKGFGFVS--FERHEDAQKAVDEMNGK-ELNGKQI 261 Query: 485 VDVQAKMRAELEYGLKK-----KSHGLATVRMLPTYVCGLPDGTE 524 +A+ + E + LK+ K + +++ YV L DG + Sbjct: 262 YVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGID 306 >gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 30.8 bits (68), Expect = 6.0 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 122 NGTELFEYVADCLADFMKTK-DLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV 180 NG L +Y+A+ +A ++ K + + L F R +L W K F+AR Sbjct: 194 NGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKE 253 Query: 181 QDTDVVSRLTKAMR 194 + T +++L +R Sbjct: 254 EKTPNITKLRTDLR 267 >gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo sapiens] Length = 1272 Score = 30.8 bits (68), Expect = 6.0 Identities = 19/74 (25%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 122 NGTELFEYVADCLADFMKTK-DLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV 180 NG L +Y+A+ +A ++ K + + L F R +L W K F+AR Sbjct: 194 NGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKE 253 Query: 181 QDTDVVSRLTKAMR 194 + T +++L +R Sbjct: 254 EKTPNITKLRTDLR 267 >gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 30.4 bits (67), Expect = 7.9 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 9/86 (10%) Query: 380 FRSANLCAAALAAILTRLRENKKVE------RLRTTVGMDGTLYKIHP---QYPKRLHKV 430 F+ L A + + +L +N E RL TT+G D K P QY ++ K+ Sbjct: 906 FKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI 965 Query: 431 VRKLVPSCDVRFLLSESGSTKGAAMV 456 +++ S +RF+L + +G+ V Sbjct: 966 IKEKKTSSRIRFMLQDVLDLRGSNWV 991 >gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 isoform 2 [Homo sapiens] Length = 1512 Score = 30.4 bits (67), Expect = 7.9 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 9/86 (10%) Query: 380 FRSANLCAAALAAILTRLRENKKVE------RLRTTVGMDGTLYKIHP---QYPKRLHKV 430 F+ L A + + +L +N E RL TT+G D K P QY ++ K+ Sbjct: 819 FKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI 878 Query: 431 VRKLVPSCDVRFLLSESGSTKGAAMV 456 +++ S +RF+L + +G+ V Sbjct: 879 IKEKKTSSRIRFMLQDVLDLRGSNWV 904 >gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 isoform 3 [Homo sapiens] Length = 1435 Score = 30.4 bits (67), Expect = 7.9 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 9/86 (10%) Query: 380 FRSANLCAAALAAILTRLRENKKVE------RLRTTVGMDGTLYKIHP---QYPKRLHKV 430 F+ L A + + +L +N E RL TT+G D K P QY ++ K+ Sbjct: 742 FKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI 801 Query: 431 VRKLVPSCDVRFLLSESGSTKGAAMV 456 +++ S +RF+L + +G+ V Sbjct: 802 IKEKKTSSRIRFMLQDVLDLRGSNWV 827 >gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 30.4 bits (67), Expect = 7.9 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 9/86 (10%) Query: 380 FRSANLCAAALAAILTRLRENKKVE------RLRTTVGMDGTLYKIHP---QYPKRLHKV 430 F+ L A + + +L +N E RL TT+G D K P QY ++ K+ Sbjct: 906 FKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI 965 Query: 431 VRKLVPSCDVRFLLSESGSTKGAAMV 456 +++ S +RF+L + +G+ V Sbjct: 966 IKEKKTSSRIRFMLQDVLDLRGSNWV 991 >gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 isoform 4 [Homo sapiens] Length = 1403 Score = 30.4 bits (67), Expect = 7.9 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 9/86 (10%) Query: 380 FRSANLCAAALAAILTRLRENKKVE------RLRTTVGMDGTLYKIHP---QYPKRLHKV 430 F+ L A + + +L +N E RL TT+G D K P QY ++ K+ Sbjct: 710 FKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI 769 Query: 431 VRKLVPSCDVRFLLSESGSTKGAAMV 456 +++ S +RF+L + +G+ V Sbjct: 770 IKEKKTSSRIRFMLQDVLDLRGSNWV 795 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.138 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,048,677 Number of Sequences: 37866 Number of extensions: 1391632 Number of successful extensions: 2786 Number of sequences better than 10.0: 24 Number of HSP's better than 10.0 without gapping: 11 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 2725 Number of HSP's gapped (non-prelim): 41 length of query: 917 length of database: 18,247,518 effective HSP length: 111 effective length of query: 806 effective length of database: 14,044,392 effective search space: 11319779952 effective search space used: 11319779952 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.