BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens] (791 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens] 1565 0.0 gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] 1506 0.0 gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] 1491 0.0 gi|56119110 family with sequence similarity 13, member A1 isofor... 484 e-136 gi|62865869 family with sequence similarity 13, member A1 isofor... 427 e-119 gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens] 242 9e-64 gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo sapi... 242 9e-64 gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens] 137 3e-32 gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 55 3e-07 gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 55 3e-07 gi|208022687 GTPase regulator associated with the focal adhesion... 50 8e-06 gi|7662208 GTPase regulator associated with the focal adhesion k... 50 8e-06 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 49 2e-05 gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 49 2e-05 gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 49 2e-05 gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 49 2e-05 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 49 2e-05 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 49 2e-05 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 48 4e-05 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 47 5e-05 gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 46 1e-04 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 46 2e-04 gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 45 2e-04 gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 45 3e-04 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 4e-04 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 44 4e-04 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 44 4e-04 gi|4758648 kinesin family member 5B [Homo sapiens] 44 6e-04 gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 44 6e-04 gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 44 6e-04 >gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens] Length = 791 Score = 1565 bits (4053), Expect = 0.0 Identities = 791/791 (100%), Positives = 791/791 (100%) Query: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG Sbjct: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60 Query: 61 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE Sbjct: 61 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120 Query: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI Sbjct: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180 Query: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN Sbjct: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240 Query: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY Sbjct: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300 Query: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK Sbjct: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360 Query: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC Sbjct: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420 Query: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL Sbjct: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480 Query: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT Sbjct: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540 Query: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED Sbjct: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600 Query: 601 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 660 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE Sbjct: 601 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 660 Query: 661 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 720 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL Sbjct: 661 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 720 Query: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV Sbjct: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780 Query: 781 LISKQDSSKSI 791 LISKQDSSKSI Sbjct: 781 LISKQDSSKSI 791 >gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] Length = 887 Score = 1506 bits (3900), Expect = 0.0 Identities = 769/791 (97%), Positives = 769/791 (97%), Gaps = 22/791 (2%) Query: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG Sbjct: 119 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 178 Query: 61 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE Sbjct: 179 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 238 Query: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI Sbjct: 239 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 298 Query: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN Sbjct: 299 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 358 Query: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY Sbjct: 359 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 418 Query: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK Sbjct: 419 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 478 Query: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420 WE EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC Sbjct: 479 WE----------------------EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 516 Query: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL Sbjct: 517 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 576 Query: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT Sbjct: 577 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 636 Query: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED Sbjct: 637 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 696 Query: 601 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 660 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE Sbjct: 697 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 756 Query: 661 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 720 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL Sbjct: 757 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 816 Query: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV Sbjct: 817 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 876 Query: 781 LISKQDSSKSI 791 LISKQDSSKSI Sbjct: 877 LISKQDSSKSI 887 >gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] Length = 915 Score = 1491 bits (3861), Expect = 0.0 Identities = 769/819 (93%), Positives = 769/819 (93%), Gaps = 50/819 (6%) Query: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG Sbjct: 119 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 178 Query: 61 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE Sbjct: 179 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 238 Query: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI Sbjct: 239 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 298 Query: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN Sbjct: 299 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 358 Query: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY Sbjct: 359 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 418 Query: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK Sbjct: 419 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 478 Query: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420 W EEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC Sbjct: 479 W----------------------EEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 516 Query: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL Sbjct: 517 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 576 Query: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT Sbjct: 577 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 636 Query: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED Sbjct: 637 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 696 Query: 601 IK----------------------------VTKEERHIVKPLYDRYRLVKQMLTRASITP 632 IK VTKEERHIVKPLYDRYRLVKQMLTRASITP Sbjct: 697 IKKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITP 756 Query: 633 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS Sbjct: 757 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 816 Query: 693 ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN 752 ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN Sbjct: 817 ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN 876 Query: 753 AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 791 AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI Sbjct: 877 AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 915 >gi|56119110 family with sequence similarity 13, member A1 isoform a [Homo sapiens] Length = 1023 Score = 484 bits (1247), Expect = e-136 Identities = 348/925 (37%), Positives = 492/925 (53%), Gaps = 173/925 (18%) Query: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVF 59 +QL QD N+ + LR L+++LP +Y LLK+LC+FL VA HH + + ++LA VF Sbjct: 138 IQLFQDGRNDVQES-SLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVF 196 Query: 60 GPDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENE------------------EEDF 101 GP+ FH+ +E MKEQ++ ++IMA +LENY FE E +E + Sbjct: 197 GPNCFHVPPGLEGMKEQDLCNKIMAKILENYNTLFEVEYTENDHLRCENLARLIIVKEVY 256 Query: 102 SSNDL------------------SSITEQVNELSEEEEEDEKLEHIEELPEEGAEKSNDM 143 N L + I + +E S + + E + +P+ S Sbjct: 257 YKNSLPILLTRGLERDMPKPPPKTKIPKSRSEGSIQAHRVLQPELSDGIPQLSLRLSYRK 316 Query: 144 PEVVQLRMTENILESNSVTAT------------STHISPISILPASTDILERTIRAAVEQ 191 + + E + + V ++ S H+ +S + A+ ++LERTIR+AVEQ Sbjct: 317 ACLEDMNSAEGAISAKLVPSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQ 376 Query: 192 HLFDL-----QSSIDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID----- 233 HLFD+ QSS D + L S + E H +G N+ + Sbjct: 377 HLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGF 436 Query: 234 --IADDIINASESNR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQS 276 + D I+N E + + SKP +ST L QD + E+ +T+S Sbjct: 437 NHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRS 496 Query: 277 VGIL----LEPCSD--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEV 330 E SD +G+ +DG + F+S + KI + + ++++ Sbjct: 497 HERTGPDDFEWMSDERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQ 543 Query: 331 PGGQSVGVQGEAACVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAF 390 Q G Q E+ +P DL + D WE EP PAF Sbjct: 544 QRNQDAGDQEESFVSEVPQSDLTALCDEKNWE----------------------EPIPAF 581 Query: 391 KSWQ-EDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSK 449 SWQ E+S+S EA LSPQAGR+ L+ED P+LS R +GQS+++L D E S Sbjct: 582 SSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPN 641 Query: 450 ALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAA 506 + SF R R SS S D+++ED TP QL +++Q KKIR+FE++FE E+ +PS+SD AA Sbjct: 642 SHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAA 701 Query: 507 NPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEP 566 NP+VLKW +L K R+Q+K++K K S+ + P+ R RSNTLPKSFGS L+ EDE+ ++ Sbjct: 702 NPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQE-- 759 Query: 567 KVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK------------------------ 602 ++ K KPS EATLE I ++L+EKR E PEDIK Sbjct: 760 -LVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESI 818 Query: 603 ----VTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFF 658 VTK ER ++KPLYDRYRLVKQ+L+RA+ P++GSPS+KRR +LQPIIEGETA FF Sbjct: 819 HGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFF 878 Query: 659 EEIKEEEE---DGVNLSSELGDMLKTAVQVQSSLENSESDVE--------ENQEKLALDL 707 +EIKEEEE D N+ + LKT + L+ E D + + K + D Sbjct: 879 KEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDT 938 Query: 708 RLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYRE 767 LS+ AAS+PELLE L + R EKK++RK LR+FE+ F++QNGRN QKEDR P+ EEY E Sbjct: 939 GLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSE 998 Query: 768 YKKIKAKLRLLEVLISKQDS-SKSI 791 YK IKAKLRLLEVLISK+D+ SKS+ Sbjct: 999 YKHIKAKLRLLEVLISKRDTDSKSM 1023 >gi|62865869 family with sequence similarity 13, member A1 isoform b [Homo sapiens] Length = 697 Score = 427 bits (1097), Expect = e-119 Identities = 295/732 (40%), Positives = 407/732 (55%), Gaps = 123/732 (16%) Query: 145 EVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDL-----QSS 199 E++ L+ ++ S S H+ +S + A+ ++LERTIR+AVEQHLFD+ QSS Sbjct: 4 EIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSS 63 Query: 200 IDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID-------IADDIINASES 244 D + L S + E H +G N+ + + D I+N E Sbjct: 64 EDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEV 123 Query: 245 NR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQSVGIL----LEPCS 285 + + SKP +ST L QD + E+ +T+S E S Sbjct: 124 EKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMS 183 Query: 286 D--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAA 343 D +G+ +DG + F+S + KI + + ++++ Q G Q E+ Sbjct: 184 DERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQQRNQDAGDQEESF 230 Query: 344 CVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQ-EDSESGEA 402 +P DL + D WE EP PAF SWQ E+S+S EA Sbjct: 231 VSEVPQSDLTALCDEKNWE----------------------EPIPAFSSWQRENSDSDEA 268 Query: 403 QLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS 462 LSPQAGR+ L+ED P+LS R +GQS+++L D E S + SF R R SS Sbjct: 269 HLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLG 328 Query: 463 SKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTK 519 S D+++ED TP QL +++Q KKIR+FE++FE E+ +PS+SD AANP+VLKW +L K Sbjct: 329 SYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAK 388 Query: 520 LRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEA 579 R+Q+K++K K S+ + P+ R RSNTLPKSFGS L+ EDE+ ++ ++ K KPS EA Sbjct: 389 FRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVDKAIKPSVEA 445 Query: 580 TLELILKRLKEKRIERCLPEDIK----------------------------VTKEERHIV 611 TLE I ++L+EKR E PEDIK VTK ER ++ Sbjct: 446 TLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVM 505 Query: 612 KPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEE---DG 668 KPLYDRYRLVKQ+L+RA+ P++GSPS+KRR +LQPIIEGETA FF+EIKEEEE D Sbjct: 506 KPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDD 565 Query: 669 VNLSSELGDMLKTAVQVQSSLENSESDVE--------ENQEKLALDLRLSSSRAASMPEL 720 N+ + LKT + L+ E D + + K + D LS+ AAS+PEL Sbjct: 566 SNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPEL 625 Query: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780 LE L + R EKK++RK LR+FE+ F++QNGRN QKEDR P+ EEY EYK IKAKLRLLEV Sbjct: 626 LEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEV 685 Query: 781 LISKQDS-SKSI 791 LISK+D+ SKS+ Sbjct: 686 LISKRDTDSKSM 697 >gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens] Length = 585 Score = 242 bits (618), Expect = 9e-64 Identities = 164/424 (38%), Positives = 238/424 (56%), Gaps = 47/424 (11%) Query: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440 D +P P K Q +++S L S R+ +H + D P+LS R F QSQRF D Sbjct: 195 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 253 Query: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497 PE S F R SS S + +E +T QL K +Q +KIR+FEE+FE+E+ Sbjct: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313 Query: 498 KPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NTLPKSF 551 +PS+ D +NP+VLKWM +L K RKQ+K+ K K S+ + P+ PR+ T+P+ Sbjct: 314 RPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPREN 373 Query: 552 GSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIV 611 G +P+ E S E T + L LKE+R + ED KVTK++++++ Sbjct: 374 G------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLI 421 Query: 612 KPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEED 667 KPLYDRYR++KQ+L+ S+ P + S + +G QP + +H D Sbjct: 422 KPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGD 474 Query: 668 GVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKA 727 + S+E V++ L + + +V+ L +S+ A+MP LL+ L + Sbjct: 475 HLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRET 521 Query: 728 RAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787 RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD Sbjct: 522 RADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDV 581 Query: 788 SKSI 791 +K+I Sbjct: 582 AKTI 585 >gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo sapiens] Length = 502 Score = 242 bits (618), Expect = 9e-64 Identities = 164/424 (38%), Positives = 238/424 (56%), Gaps = 47/424 (11%) Query: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440 D +P P K Q +++S L S R+ +H + D P+LS R F QSQRF D Sbjct: 112 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 170 Query: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497 PE S F R SS S + +E +T QL K +Q +KIR+FEE+FE+E+ Sbjct: 171 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 230 Query: 498 KPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NTLPKSF 551 +PS+ D +NP+VLKWM +L K RKQ+K+ K K S+ + P+ PR+ T+P+ Sbjct: 231 RPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPREN 290 Query: 552 GSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIV 611 G +P+ E S E T + L LKE+R + ED KVTK++++++ Sbjct: 291 G------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLI 338 Query: 612 KPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEED 667 KPLYDRYR++KQ+L+ S+ P + S + +G QP + +H D Sbjct: 339 KPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGD 391 Query: 668 GVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKA 727 + S+E V++ L + + +V+ L +S+ A+MP LL+ L + Sbjct: 392 HLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRET 438 Query: 728 RAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787 RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD Sbjct: 439 RADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDV 498 Query: 788 SKSI 791 +K+I Sbjct: 499 AKTI 502 >gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens] Length = 487 Score = 137 bits (346), Expect = 3e-32 Identities = 89/227 (39%), Positives = 134/227 (59%), Gaps = 28/227 (12%) Query: 573 KKPSKEATLELILKRLKEK--RIERCLPEDIK--VTKEERHIVKPLYDRYRLVKQMLTRA 628 K+P L ++ LK K + E ++ K VTK++++++KPLYDRYR++KQ+L+ Sbjct: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTP 340 Query: 629 SITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQ 684 S+ P + S + +G QP + +H D + S+E Sbjct: 341 SLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGDHLTYSNE-------TEP 386 Query: 685 VQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEA 744 V++ L + + +V+ L +S+ A+MP LL+ L + RA+KK+LRK LREFEE Sbjct: 387 VRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQ 440 Query: 745 FYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 791 F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD +K+I Sbjct: 441 FFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 487 Score = 78.2 bits (191), Expect = 3e-14 Identities = 71/239 (29%), Positives = 109/239 (45%), Gaps = 31/239 (12%) Query: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440 D +P P K Q +++S L S R+ +H + D P+LS R F QSQRF D Sbjct: 195 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 253 Query: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497 PE S F R SS S + +E +T QL K +Q +KIR+FEE+FE+E+ Sbjct: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313 Query: 498 KPSYSD------IAANPKVLKWMTELTKLRKQIKDAKHKNSD---GEFVPQTRPRSNTLP 548 + + D + +++K + L I++ + + D G P ++ LP Sbjct: 314 RVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 373 Query: 549 KSFGSSLDHEDEENEDEP--KVIQKEKKPSK----------EATLELILKRLKEKRIER 595 DH NE EP ++ EKK K EAT+ ++L L+E R ++ Sbjct: 374 VG-----DHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK 427 Score = 32.0 bits (71), Expect = 2.3 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 4/69 (5%) Query: 436 RFLHDPEKLDSSSKALSFTRIRRSSFSSK-DEKREDRTPYQLVKKLQKKIRQFEEQFERE 494 R L EK + ALS + + ++ D RE R K+L+K +R+FEEQF ++ Sbjct: 388 RALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK---KRLRKALREFEEQFFKQ 444 Query: 495 RNSKPSYSD 503 P D Sbjct: 445 TGRSPQKED 453 >gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 [Homo sapiens] Length = 1288 Score = 54.7 bits (130), Expect = 3e-07 Identities = 65/295 (22%), Positives = 128/295 (43%), Gaps = 29/295 (9%) Query: 442 EKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSY 501 EK+ +K ++ +S+ S + K +++ KKL K + EE +E+ ++ Sbjct: 342 EKIHEDTKEIN----EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEEN--KEKFTQLDL 395 Query: 502 SDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVP--------QTRPRSNTLPKSFGS 553 D+ K+ ++ KL KQ++ K K + + +P +T R+N L K Sbjct: 396 EDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEK 455 Query: 554 S---LDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHI 610 L + + E + +QKEK+ S+E L K + E R + + V + E I Sbjct: 456 EEKKLKEVMDSLKQETQGLQKEKE-SREKELMGFSKSVNEARSK------MDVAQSELDI 508 Query: 611 VKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVN 670 R+ LT+A + S + K R ++ I EG+ +E+KE+E++ Sbjct: 509 Y---LSRHNTAVSQLTKAKEALIAASETLKERKAAIRDI-EGKLPQTEQELKEKEKELQK 564 Query: 671 LSSELGDMLKTAVQVQSSLENSESDVEENQEK-LALDLRLSSSRAASMPELLEQL 724 L+ E + + +E ++S + N+ + LD + ++ +P + +L Sbjct: 565 LTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRL 619 Score = 32.7 bits (73), Expect = 1.3 Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 12/146 (8%) Query: 650 IEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLA-LDLR 708 +E + E+ KE E LS+E+ K + L +EEN+EK LDL Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLE 396 Query: 709 LSSSRAASMPELLEQLWKARAEKKKLRKTL---REFEEAFYQQNGRNAQKEDRVPVLEEY 765 R E+L A ++ KKL K L +E E F ++ + Sbjct: 397 DVQVR--------EKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNA 448 Query: 766 REYKKIKAKLRLLEVLISKQDSSKSI 791 E +K K + +L EV+ S + ++ + Sbjct: 449 LEKEKEKEEKKLKEVMDSLKQETQGL 474 >gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 [Homo sapiens] Length = 1288 Score = 54.7 bits (130), Expect = 3e-07 Identities = 65/295 (22%), Positives = 128/295 (43%), Gaps = 29/295 (9%) Query: 442 EKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSY 501 EK+ +K ++ +S+ S + K +++ KKL K + EE +E+ ++ Sbjct: 342 EKIHEDTKEIN----EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEEN--KEKFTQLDL 395 Query: 502 SDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVP--------QTRPRSNTLPKSFGS 553 D+ K+ ++ KL KQ++ K K + + +P +T R+N L K Sbjct: 396 EDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEK 455 Query: 554 S---LDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHI 610 L + + E + +QKEK+ S+E L K + E R + + V + E I Sbjct: 456 EEKKLKEVMDSLKQETQGLQKEKE-SREKELMGFSKSVNEARSK------MDVAQSELDI 508 Query: 611 VKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVN 670 R+ LT+A + S + K R ++ I EG+ +E+KE+E++ Sbjct: 509 Y---LSRHNTAVSQLTKAKEALIAASETLKERKAAIRDI-EGKLPQTEQELKEKEKELQK 564 Query: 671 LSSELGDMLKTAVQVQSSLENSESDVEENQEK-LALDLRLSSSRAASMPELLEQL 724 L+ E + + +E ++S + N+ + LD + ++ +P + +L Sbjct: 565 LTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRL 619 Score = 32.7 bits (73), Expect = 1.3 Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 12/146 (8%) Query: 650 IEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLA-LDLR 708 +E + E+ KE E LS+E+ K + L +EEN+EK LDL Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLE 396 Query: 709 LSSSRAASMPELLEQLWKARAEKKKLRKTL---REFEEAFYQQNGRNAQKEDRVPVLEEY 765 R E+L A ++ KKL K L +E E F ++ + Sbjct: 397 DVQVR--------EKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNA 448 Query: 766 REYKKIKAKLRLLEVLISKQDSSKSI 791 E +K K + +L EV+ S + ++ + Sbjct: 449 LEKEKEKEEKKLKEVMDSLKQETQGL 474 >gi|208022687 GTPase regulator associated with the focal adhesion kinase pp125 isoform b [Homo sapiens] Length = 759 Score = 50.1 bits (118), Expect = 8e-06 Identities = 41/173 (23%), Positives = 75/173 (43%), Gaps = 21/173 (12%) Query: 9 NEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEE-IWSANSLAAVFGPDVFHIY 67 N++ ++ L+ +LP N +L+ L LANVA++H++ + + +L VFGP + Sbjct: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540 Query: 68 TD----VEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEED 123 + + D+K Q IV I+ EN E+ F++ +T LS ++ D Sbjct: 541 EETVAAIMDIKFQNIVIEIL----------IENHEKIFNTVPDMPLTNAQLHLSRKKSSD 590 Query: 124 EKLEHIEELP------EEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISP 170 K E P + EK ++ + NS+ +S+ + P Sbjct: 591 SKPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQP 643 >gi|7662208 GTPase regulator associated with the focal adhesion kinase pp125 isoform a [Homo sapiens] Length = 814 Score = 50.1 bits (118), Expect = 8e-06 Identities = 41/173 (23%), Positives = 75/173 (43%), Gaps = 21/173 (12%) Query: 9 NEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEE-IWSANSLAAVFGPDVFHIY 67 N++ ++ L+ +LP N +L+ L LANVA++H++ + + +L VFGP + Sbjct: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540 Query: 68 TD----VEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEED 123 + + D+K Q IV I+ EN E+ F++ +T LS ++ D Sbjct: 541 EETVAAIMDIKFQNIVIEIL----------IENHEKIFNTVPDMPLTNAQLHLSRKKSSD 590 Query: 124 EKLEHIEELP------EEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISP 170 K E P + EK ++ + NS+ +S+ + P Sbjct: 591 SKPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQP 643 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 48.9 bits (115), Expect = 2e-05 Identities = 62/314 (19%), Positives = 138/314 (43%), Gaps = 20/314 (6%) Query: 477 VKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQI-----KDAKHKN 531 +++ ++KIR+ EE+ R+ + + + W E K+R+Q K+ K + Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKIRE 442 Query: 532 SDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEK 591 + + Q + R + + +++ E E K+ ++E+K ++ E ++ +EK Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ---EEKIREQEEK 499 Query: 592 --RIERCLPEDIKVTKEE-RHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQP 648 R E + E K+ +EE R + ++ + +++ + K R Q + Sbjct: 500 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559 Query: 649 IIEGETAHFFEE-IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDL 707 + E H EE I+E+EE ++ + + + + + E +E +EK+ Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE 619 Query: 708 RLSSSRAASMPELLEQLW----KARAEKKKLRKT---LREFEEAFYQQNGRNAQKEDRVP 760 + M E E++ K R ++KK+R+ +RE EE +Q + ++E+++ Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 679 Query: 761 VLEEYREYKKIKAK 774 EE + ++ K + Sbjct: 680 EQEEKMQEQEEKMR 693 Score = 47.0 bits (110), Expect = 7e-05 Identities = 52/339 (15%), Positives = 147/339 (43%), Gaps = 26/339 (7%) Query: 455 RIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQ-FERERNSKPSYSDIAANPKVLKW 513 +IR ++++ + R +++ + ++K+R+ EE +E+E + + + ++ Sbjct: 383 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 442 Query: 514 MTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSS---LDHEDEENEDEPKVIQ 570 + E +++I++ + K + E + + R K + + E++ E E K+ + Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWR 502 Query: 571 KEKKPSKEATLELILKRLKEKRI-----------------ERCLPEDIKVTKEERHIVKP 613 +E+K ++ + KR +++ + E+ ++ K+ K+E + + Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562 Query: 614 ---LYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGE--TAHFFEEIKEEEEDG 668 ++D+ +++ + ++ + + I E E T E++ E+EE Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 622 Query: 669 VNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKAR 728 ++ + + + + + E + E +EK+ + + M E E++ + Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682 Query: 729 AEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYRE 767 + ++ + +R EE ++Q R Q+E+++ +E+ E Sbjct: 683 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721 Score = 39.3 bits (90), Expect = 0.014 Identities = 47/236 (19%), Positives = 109/236 (46%), Gaps = 23/236 (9%) Query: 559 DEENEDEPKVIQKEKK--PSKEATLELILKRLKEK--RIERCLPEDIKVTKEERHIVKPL 614 DEE +++ +Q++ + S+++ ++L +K LK K R + LP+ ++ E H+ K L Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKEL 335 Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674 ++ + + L ++ + + I E E E+I+E+EE + Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE-----EKIQEQEE-------K 383 Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734 + + + + + + E + E +EK+ + + M E +W+ + ++L Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 443 Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYK----KIKAKLRLLEVLISKQD 786 + + E E+ Q+ R Q+E+++ E+ +E + + + K+R E I +Q+ Sbjct: 444 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497 Score = 31.2 bits (69), Expect = 3.9 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 5/87 (5%) Query: 66 IYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEE---- 121 ++ E ++EQE R + E + +EE + + EQ ++ E+EE Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE-EKMCEQEEKMQEQEEKMRR 638 Query: 122 EDEKLEHIEELPEEGAEKSNDMPEVVQ 148 ++EK+ E+ E EK + E++Q Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQ 665 >gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sapiens] Length = 653 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 8/98 (8%) Query: 8 NNEDEFG-RKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFH 65 + E+E G ++L ++ LP VNY+LLK++CRFL V S+ S +LA VFGP++ Sbjct: 144 SKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI-- 201 Query: 66 IYTDVED----MKEQEIVSRIMAGLLENYYEFFENEEE 99 + VED M+ +V ++M+ ++ + F + E Sbjct: 202 LRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAE 239 >gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sapiens] Length = 655 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 8/98 (8%) Query: 8 NNEDEFG-RKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFH 65 + E+E G ++L ++ LP VNY+LLK++CRFL V S+ S +LA VFGP++ Sbjct: 146 SKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI-- 203 Query: 66 IYTDVED----MKEQEIVSRIMAGLLENYYEFFENEEE 99 + VED M+ +V ++M+ ++ + F + E Sbjct: 204 LRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAE 241 >gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sapiens] Length = 748 Score = 48.5 bits (114), Expect = 2e-05 Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 8/98 (8%) Query: 8 NNEDEFG-RKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFH 65 + E+E G ++L ++ LP VNY+LLK++CRFL V S+ S +LA VFGP++ Sbjct: 239 SKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI-- 296 Query: 66 IYTDVED----MKEQEIVSRIMAGLLENYYEFFENEEE 99 + VED M+ +V ++M+ ++ + F + E Sbjct: 297 LRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAE 334 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 48.5 bits (114), Expect = 2e-05 Identities = 63/278 (22%), Positives = 112/278 (40%), Gaps = 34/278 (12%) Query: 426 HRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS---SKDEKREDRTPYQLVKKLQK 482 HRS +S+ D + S K S +R RR S S S+D++++ R + +++++ Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 392 Query: 483 KIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRP 542 K R+ E + E+ER K+ + K+K+ D E + R Sbjct: 393 KDREKEREREKERE-------------------------KEKERGKNKDRDKER-EKDRE 426 Query: 543 RSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK 602 + + +HE + ++++ K KEK+ K+ + E+ KR K+K+ R P Sbjct: 427 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTPPRSYN 485 Query: 603 VTKEERHIVKPLYDRYRLVKQMLTRASIT---PVLGSPSTKRRGQMLQPIIEGETAHFFE 659 ++ R + R R S T SPS + R + E E H E Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK-DKKREKERDHISE 544 Query: 660 EIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697 + E + SS D + + +SL+ E + E Sbjct: 545 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 582 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 48.5 bits (114), Expect = 2e-05 Identities = 63/278 (22%), Positives = 112/278 (40%), Gaps = 34/278 (12%) Query: 426 HRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS---SKDEKREDRTPYQLVKKLQK 482 HRS +S+ D + S K S +R RR S S S+D++++ R + +++++ Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 276 Query: 483 KIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRP 542 K R+ E + E+ER K+ + K+K+ D E + R Sbjct: 277 KDREKEREREKERE-------------------------KEKERGKNKDRDKER-EKDRE 310 Query: 543 RSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK 602 + + +HE + ++++ K KEK+ K+ + E+ KR K+K+ R P Sbjct: 311 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTPPRSYN 369 Query: 603 VTKEERHIVKPLYDRYRLVKQMLTRASIT---PVLGSPSTKRRGQMLQPIIEGETAHFFE 659 ++ R + R R S T SPS + R + E E H E Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK-DKKREKERDHISE 428 Query: 660 EIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697 + E + SS D + + +SL+ E + E Sbjct: 429 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 466 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 47.8 bits (112), Expect = 4e-05 Identities = 59/335 (17%), Positives = 145/335 (43%), Gaps = 75/335 (22%) Query: 464 KDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQ 523 ++EK ++R + +++ ++KIR+ EE+ R+ + + + W E ++ Sbjct: 293 QEEKIQERE--EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-----EK 345 Query: 524 IKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL 583 I++ + K + E + + ++E+ ++E K+ ++EK+ +EA + Sbjct: 346 IRELEEKMHEQEKIRE------------------QEEKRQEEEKIREQEKRQEQEAKMWR 387 Query: 584 ILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRG 643 ++++E+ + E++ +EE+ G Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEK---------------------------------MG 414 Query: 644 QMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKL 703 + + + E E EE++E+EE ++ + K + + + E ++E +EK+ Sbjct: 415 EQEEKMWEQE-----EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469 Query: 704 ALDLRLSSSRAASMPELLEQL----WKARAEKKKLR---KTLREFEEAFYQQNGRNAQKE 756 + A M E E++ K R ++KK+R + +RE EE +Q + ++E Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529 Query: 757 DRV-----PVLEEYREYKKIKAKLRLLEVLISKQD 786 +++ + E+ + ++ + K+R EV + +Q+ Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQE 564 Score = 33.1 bits (74), Expect = 1.0 Identities = 45/236 (19%), Positives = 102/236 (43%), Gaps = 44/236 (18%) Query: 559 DEENEDEPKVIQKEKK--PSKEATLELILKRLKEK--RIERCLPEDIKVTKEERHIVKPL 614 DEE +++ +Q++ + S+++ ++L +K LK K R + LP+ ++ E H+ K L Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKEL 262 Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674 S S K + Q+ E + + +++E+ + E Sbjct: 263 Q--------------------SVSAKLQAQV-------EENELWNRLNQQQEEKMWRQEE 295 Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734 + + ++ E + E +EK+ + + M E +W+ + ++L Sbjct: 296 ------KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 349 Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYK----KIKAKLRLLEVLISKQD 786 + + E E+ Q+ R Q+E+++ E+ +E + + + K+R E I +Q+ Sbjct: 350 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403 Score = 30.4 bits (67), Expect = 6.7 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 5/82 (6%) Query: 71 EDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEE----EDEKL 126 E ++EQE R + E + +EE + + EQ ++ E+EE ++EK+ Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE-GKMCEQEAKMQEQEEKMRRQEEKI 497 Query: 127 EHIEELPEEGAEKSNDMPEVVQ 148 E+ E EK + E++Q Sbjct: 498 REQEKKIREQEEKIREQEEMMQ 519 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 47.4 bits (111), Expect = 5e-05 Identities = 64/345 (18%), Positives = 146/345 (42%), Gaps = 33/345 (9%) Query: 434 SQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFER 493 ++R+ D + +S ++R +F+ D++ + VKK +++ ++ + Sbjct: 81 TKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQE 140 Query: 494 ERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGS 553 + N K +Y+ RK++ K GE Q RP ++ L ++ Sbjct: 141 KMNEK-NYT-----------------FRKRVVIKKPWLRLGEVTAQKRPENSLLEETL-- 180 Query: 554 SLDHEDEENEDEPKVIQKEKKPSKEATLELIL-KRLKEKRIERCLPEDIKVTKEERHIVK 612 DH K+ ++ PS E I + LKEK E L E +++ + E+ ++ Sbjct: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAE--LQEKLRLVESEKSEIQ 238 Query: 613 PLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLS 672 + +K+ L RA + +L + L ++ +A +++E E + Sbjct: 239 L---NVKDLKRKLERAQL--LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293 Query: 673 SELGDMLKTAVQVQSSLEN---SESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARA 729 + M + ++Q E E + E +EK+ + + E +++W+ Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353 Query: 730 EKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEE--YREYKKIK 772 + ++ + +RE EE ++Q + ++++++ EE +R+ +KI+ Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR 398 Score = 39.3 bits (90), Expect = 0.014 Identities = 45/232 (19%), Positives = 110/232 (47%), Gaps = 24/232 (10%) Query: 557 HEDEEN--EDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPL 614 HE EE E E K+ ++E+K ++ ++++E+ E+ ++ K+ +++ I + Sbjct: 335 HEQEEKIREQEDKMWRQEEKIREQE------EKIREQE-EKMWRQEEKIREQDEKIQEQE 387 Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674 + +R +++ + KR+ +M + E + E+I+E+EE+ + Sbjct: 388 EEMWRQEEKIREQEE----------KRQEKMWRQ--EKKMREQDEKIREQEEEMWRQEEK 435 Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734 + ++ + + L E ++E +EK+ + + E E+ W+ K+ Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495 Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQD 786 K + E EE ++Q + ++E+++ EE + ++ + K+R EV + +Q+ Sbjct: 496 EK-IWEQEEKMWRQEEKMWEQEEKMQEQEE--KMQRQEEKMREQEVRLWQQE 544 Score = 35.0 bits (79), Expect = 0.27 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 8/93 (8%) Query: 71 EDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEE-EEEDEKLEHI 129 ++ K QE + R + E + E EEE + E++ EL E ++++EKL + Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE------EKIRELEEMMQDQEEKLREV 453 Query: 130 EELPEEGAEKSNDMPEVVQLRMTENILESNSVT 162 EE +E EK + E +Q R E I E T Sbjct: 454 EEKMQEEEEKMQEQEEKIQ-RQEEKIQEQEEKT 485 Score = 34.7 bits (78), Expect = 0.35 Identities = 51/299 (17%), Positives = 128/299 (42%), Gaps = 25/299 (8%) Query: 469 EDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQ---IK 525 E+ + L+ + Q++ +E+ +E+ K ++ + K + K+ +Q I+ Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342 Query: 526 DAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELIL 585 + + K E + R + + + E++ E + K+ ++E++ ++ E + Sbjct: 343 EQEDKMWRQE--EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ---EEKI 397 Query: 586 KRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQM 645 + +EKR E+ ++ K+ +++ I + + +R +++ + +M Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI---------------RELEEM 442 Query: 646 LQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLAL 705 +Q + E EE +EEE+ + E + +Q Q + + + +EK+ Sbjct: 443 MQD--QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500 Query: 706 DLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEE 764 + M E E++ + + ++ + +RE E +QQ + ++E R+ LEE Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559 >gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] Length = 1780 Score = 46.2 bits (108), Expect = 1e-04 Identities = 60/332 (18%), Positives = 146/332 (43%), Gaps = 31/332 (9%) Query: 476 LVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKH------ 529 ++ KL++ +++F+E + +S + D+ N K LK E+T+L ++D KH Sbjct: 1153 IILKLERNLKEFQEHLQ---DSVKNTKDL--NVKELKLKEEITQLTNNLQDMKHLLQLKE 1207 Query: 530 -----KNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELI 584 + E + + S+ ++ + L ++E+ D + + KK K+ E+ Sbjct: 1208 EEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVS 1267 Query: 585 LKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRG- 643 + R ++K + + E + K++ + L + R ++Q+ + + V + R Sbjct: 1268 VMRDEDKLLRIKINE---LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERAC 1324 Query: 644 ---QMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQ 700 + + IIE E+ + + E L ++L ++ + A +++ E +N Sbjct: 1325 KDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNN 1384 Query: 701 EKLALDLRLSSSRAASMPELLEQL----WKARAEKKK-LRKTLREFEEAFYQQNGRNAQK 755 ++ + ++ + L ++L K A++KK L + + +A +N RN + Sbjct: 1385 QRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEM 1444 Query: 756 EDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787 + E+ + K + ++ +L ++++DS Sbjct: 1445 K---KYAEDRERFFKQQNEMEILTAQLTEKDS 1473 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 45.8 bits (107), Expect = 2e-04 Identities = 56/312 (17%), Positives = 138/312 (44%), Gaps = 17/312 (5%) Query: 475 QLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDG 534 +L ++ +++ ++ +E ER++ P+ +D + + + + + K+ K ++ Sbjct: 99 RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 158 Query: 535 EFVPQTRPRSNTLPKSFGSS--LDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKR 592 + + + T+ KS+ + D E+ + ED+ K ++E+KP + + E ++ + E++ Sbjct: 159 RYEIE---ETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEK 215 Query: 593 IERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEG 652 E + ++ + I + +Q S + K R + + +E Sbjct: 216 TTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKM-EEEDKERAEAERARLEA 274 Query: 653 ETAHFFEEIKEEEEDGV-NLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALD----L 707 E E IK E++ + + + + K A Q + E E + +EK A + + Sbjct: 275 EER---ERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331 Query: 708 RLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYRE 767 + RAA + +++ K AE+ R+ ++E E+ ++ R +E+ +EE + Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEE---RQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR 388 Query: 768 YKKIKAKLRLLE 779 K+++ K ++ Sbjct: 389 NKQLEEKKHAMQ 400 Score = 39.3 bits (90), Expect = 0.014 Identities = 78/432 (18%), Positives = 166/432 (38%), Gaps = 54/432 (12%) Query: 391 KSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKA 450 K +ED E EA+ + E + R+ + + + E+ ++ + Sbjct: 256 KMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERE 315 Query: 451 LSFTRIRRSSFSS---KDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAAN 507 +R++ K+E++ Q +K+ +K+ + ++ + E A Sbjct: 316 RMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA 375 Query: 508 PKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED--E 565 + K E K KQ+++ KH + +T+ + + + +E + ED + Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHA------MQETKIKGEKVEQKIEGKWVNEKKAQEDKLQ 429 Query: 566 PKVIQK---EKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVK 622 V++K EK +A E + + + E E IK KE + VK DR Sbjct: 430 TAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDR----- 484 Query: 623 QMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFE------EIKEEEEDGVNLSSELG 676 + T V + G+ + ++ T + F + +E +G E G Sbjct: 485 ----KKGFTEV-----KSQNGEFMTHKLK-HTENTFSRPGGRASVDTKEAEGAP-QVEAG 533 Query: 677 DMLKTAVQVQSSLENSESD-VEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLR 735 L+ + + E+ E + +++ Q++ AL+L + ++LE+ + R +++ R Sbjct: 534 KRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADR 593 Query: 736 KTLREFE-----EAFYQQNGRNAQKEDRVP---VLEEYREYK---------KIKAKLRLL 778 K E E E ++ A+K ++P + ++ + +K KI+ + L Sbjct: 594 KLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFL 653 Query: 779 EVLISKQDSSKS 790 + K KS Sbjct: 654 NKSVQKSSGVKS 665 Score = 30.4 bits (67), Expect = 6.7 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 14/98 (14%) Query: 74 KEQEIVSRIMAGLLENYYEFFENEE--EDFSSNDLSSITEQVNELSEEEEEDEKLEHIEE 131 KE++ SR + YE E E + + ND E E E+EEE+ EE Sbjct: 149 KEEKSESR------QERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE------EE 196 Query: 132 LPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHIS 169 P+ G+ N + +V+ + TE+ E+ ++ + IS Sbjct: 197 KPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQIS 234 >gi|148762940 DVL-binding protein DAPLE [Homo sapiens] Length = 2028 Score = 45.4 bits (106), Expect = 2e-04 Identities = 62/269 (23%), Positives = 109/269 (40%), Gaps = 38/269 (14%) Query: 479 KLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKH--KNSDGEF 536 +L KKI + + Q ERE+ S ++ EL + ++Q++ K Sbjct: 505 QLSKKIEKLQTQLEREKQSNQDLETLS---------EELIREKEQLQSDMETLKADKARQ 555 Query: 537 VPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERC 596 + + L ++ S + +E K ++KE K + E K + + +R Sbjct: 556 IKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQ 615 Query: 597 LPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 656 L D++ KE+ +R +++ L R + G++ + + ETA Sbjct: 616 LHRDLEQAKEKG-------ERAEKLERELQRLQ----------EENGRLARKVTSLETAT 658 Query: 657 FFEEIKEEEEDGVNLSSE-LGDMLKTAVQVQSSLENSESDVE----ENQE--KLALDLRL 709 E E E G+ L + L L T V LE E D + EN E +L +R Sbjct: 659 EKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRF 718 Query: 710 SSSRAASMPELLEQLWKARAEKKKLRKTL 738 +S++ A M +QL EK++LRK + Sbjct: 719 TSTKLAQMERENQQL---EREKEELRKNV 744 >gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] Length = 698 Score = 45.1 bits (105), Expect = 3e-04 Identities = 32/122 (26%), Positives = 58/122 (47%), Gaps = 3/122 (2%) Query: 9 NEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASH-HEEIWSANSLAAVFGPDVF--H 65 +E E +L + LP NY+LL+++C+FL V ++ + S +LA VFGP++ Sbjct: 261 DEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQ 320 Query: 66 IYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEK 125 + V M+ +V +M L+ + + F + ++ + V SEE D + Sbjct: 321 VEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQ 380 Query: 126 LE 127 E Sbjct: 381 GE 382 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 44.3 bits (103), Expect = 4e-04 Identities = 61/335 (18%), Positives = 150/335 (44%), Gaps = 34/335 (10%) Query: 455 RIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQ-FERERNSKPSYSDIAANPKVLKW 513 +IR ++++ + R +++ + ++K+R+ EE +E+E + + + ++ Sbjct: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRE 381 Query: 514 MTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEK 573 + E +++I++ + K + E + + R K + E++ E E K+ ++EK Sbjct: 382 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ----EEKIREQEEKIREQEK 437 Query: 574 KPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPV 633 K ++ E I ++ K + E+ ++ +EE+ ++ + +R ++M + I Sbjct: 438 KMWRQE--EKIHEQEKIREEEKRQEQEEMWRQEEK--IREQEEIWRQKEKMHEQEKI--- 490 Query: 634 LGSPSTKRRGQMLQPIIEGETAHFFEE-IKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692 R Q + + E H EE I+E+EE ++ + + + + + Sbjct: 491 --------RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542 Query: 693 ESDVEENQEKLALD---LRLSSSRAASMPELLEQLWKARAEKKKLRKT----------LR 739 E ++E +EK+ ++ ++ EQ K R +K+K+R+ +R Sbjct: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIR 602 Query: 740 EFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAK 774 E EE +Q + ++E+++ EE + ++ K + Sbjct: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637 Score = 41.6 bits (96), Expect = 0.003 Identities = 48/236 (20%), Positives = 110/236 (46%), Gaps = 23/236 (9%) Query: 559 DEENEDEPKVIQKEKK--PSKEATLELILKRLKEK--RIERCLPEDIKVTKEERHIVKPL 614 DEE +++ +Q++ + S+++ ++L +K LK K R + LP+ ++ E H+ K L Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKEL 274 Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674 ++ + + L ++ + + I E E E+I+E+EE + Sbjct: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE-----EKIQEQEE-------K 322 Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734 + + + + + + E + E +EK+ + + M L E +W+ + ++L Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382 Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYK----KIKAKLRLLEVLISKQD 786 + + E E+ Q+ R Q+E+++ E+ +E + + + K+R E I +Q+ Sbjct: 383 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 44.3 bits (103), Expect = 4e-04 Identities = 79/393 (20%), Positives = 153/393 (38%), Gaps = 88/393 (22%) Query: 466 EKREDRTPYQLV--KKLQKKIRQFEEQFERERNS--KPSYSDIAANPKVLKWMTE----- 516 E+ E+R + KK+Q+ I++ EEQ E E ++ K + K+ K E Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984 Query: 517 -----LTKLRKQIKD-------------------AKHKNSDGEFVPQTRPR--------- 543 L K +K ++D AK KN + R Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044 Query: 544 --SNTLPKSFGSSLDHEDEENEDEPKVIQ-KEKKPSKEATLELILKRLKEKRIERC---- 596 T K G S D D+ E + ++ + K + KE L+ L R++E+ ++ Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104 Query: 597 -----------LPEDI--------KVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSP 637 L ED+ K K++R + + L ++ L + L S Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS- 1163 Query: 638 STKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697 ++ +L+ +E E +I+E + EL + L+ +V+++LE ++ +E Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223 Query: 698 ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKED 757 + +LA ++++ LL+ + ++KK+ L+E + F + + D Sbjct: 1224 NERGELANEVKV----------LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELAD 1273 Query: 758 RVPVLEEYREYKKIKAKLRLLEVLISKQDSSKS 790 +V K++ +L + L+S+ DS S Sbjct: 1274 KV---------TKLQVELDNVTGLLSQSDSKSS 1297 Score = 37.7 bits (86), Expect = 0.042 Identities = 70/375 (18%), Positives = 147/375 (39%), Gaps = 51/375 (13%) Query: 433 QSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFE 492 Q +R L ++ K ++R +DE+++ KKL+ ++ E + Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627 Query: 493 RERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSD-----GEFVPQTRPRSNTL 547 +AN + + +L KL+ Q+KD + D E + Q + L Sbjct: 1628 ------------SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKL 1675 Query: 548 PKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL-----------ILKRLKEKRIERC 596 S++ E + ++E ++ K+ +++ EL L +++R+E Sbjct: 1676 -----KSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEAR 1730 Query: 597 LPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 656 + + + +EE+ + + DR + + + + T + S ++ + + +E + Sbjct: 1731 IAQLEEELEEEQGNTELINDRLKKANLQIDQIN-TDLNLERSHAQKNENARQQLERQNKE 1789 Query: 657 FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQ---------EKLALDL 707 ++K +E +G S + ++ E +++ +E Q EK D+ Sbjct: 1790 L--KVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV 1847 Query: 708 RLS-SSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNG--RNAQK--EDRVPVL 762 L + + +Q KA K+L++ L E EE + N R Q+ ED Sbjct: 1848 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1907 Query: 763 EEY-REYKKIKAKLR 776 + RE +K KLR Sbjct: 1908 DAMNREVSSLKNKLR 1922 Score = 36.2 bits (82), Expect = 0.12 Identities = 52/293 (17%), Positives = 113/293 (38%), Gaps = 29/293 (9%) Query: 464 KDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQ 523 ++E R+ + +K+++ + F EQ E E +K + ++ L Q Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK------------QIATLHAQ 1365 Query: 524 IKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL 583 + D K K D +T + + + L+ + +E++ K +K EL Sbjct: 1366 VADMKKKMEDSVGCLET---AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQEL 1422 Query: 584 --ILKRLKEKRIERCLPEDIKVTKE----ERHIVKPLYDRYRLVKQMLTRASITPVLGSP 637 +L L +R C E + + E + Y R + R T L Sbjct: 1423 DDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLA 1482 Query: 638 STKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697 + +E F E+++ ++ + ++ K+ ++ +E ++ +E Sbjct: 1483 RALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 1542 Query: 698 ENQE--------KLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFE 742 E ++ KL L++ L + +A +L + ++ +KK+L + +RE E Sbjct: 1543 ELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME 1595 Score = 35.4 bits (80), Expect = 0.21 Identities = 63/338 (18%), Positives = 146/338 (43%), Gaps = 56/338 (16%) Query: 478 KKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFV 537 KK++ ++++ + +F + +D KV K EL + + Sbjct: 1248 KKVEAQLQELQVKFNEGERVRTELAD-----KVTKLQVELDNVTGLLS------------ 1290 Query: 538 PQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCL 597 Q+ +S+ L K F + + + +D +++Q+E + ++ +L LK++++++ Sbjct: 1291 -QSDSKSSKLTKDFSAL----ESQLQDTQELLQEENR--QKLSLSTKLKQVEDEK--NSF 1341 Query: 598 PEDIKVTKEERH-IVKPLYDRYRLVKQMLTRA--SITPVLGSPSTKRRGQMLQPIIEGET 654 E ++ +E +H + K + + V M + S+ + + KR+ LQ +EG + Sbjct: 1342 REQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRK---LQKDLEGLS 1398 Query: 655 AHFFEEIK---EEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE-------------- 697 E++ + E+ L EL D+L + S N E + Sbjct: 1399 QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISA 1458 Query: 698 ---ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLR-EFEEAFYQQN--GR 751 E +++ + R ++A S+ LE+ + +AE ++L K R E E+ ++ G+ Sbjct: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK 1518 Query: 752 NAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSK 789 + + ++ E ++ +++K +L LE + + +K Sbjct: 1519 SVHELEKSKRALE-QQVEEMKTQLEELEDELQATEDAK 1555 Score = 33.1 bits (74), Expect = 1.0 Identities = 50/211 (23%), Positives = 87/211 (41%), Gaps = 26/211 (12%) Query: 95 ENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEH-----IEELPEEGAEKSNDMPEVVQ- 148 EN ++ S L + ++ N E+ EE+E+ +H I L + A+ M + V Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379 Query: 149 LRMTENI---LESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDLQSSIDHDLK 205 L E + L+ + + H + A+ D LE+T + ++Q L DL +DH Sbjct: 1380 LETAEEVKRKLQKDLEGLSQRHEEKV----AAYDKLEKT-KTRLQQELDDLLVDLDH--- 1431 Query: 206 NLQQQSVVCNNEAESIHCD---GEGSNNQIDIADDIINA-SESNRDCSKPVASTNLDNEA 261 Q+ CN E + D E A++ A +E+ +K ++ EA Sbjct: 1432 ---QRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA 1488 Query: 262 MQQDCVFE--NEENTQSVGILLEPCSDRGDS 290 M+Q E N++ + L+ D G S Sbjct: 1489 MEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 44.3 bits (103), Expect = 4e-04 Identities = 76/361 (21%), Positives = 147/361 (40%), Gaps = 59/361 (16%) Query: 439 HDPEKLDSSSKALSFTRIRRSSFSSK--DEKREDRTPYQLVKKLQKKIRQFEEQFERERN 496 +D ++LD K F S SK DE+ + +K+LQ +I + EE+ E ER Sbjct: 1075 NDKQQLDEKLKKKEF---EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERA 1131 Query: 497 SKPSYSDIAANPKVLKWMTELTKLRKQIKDA---------KHKNSDGEFVPQTR------ 541 S+ A + EL ++ +++++A +K + EF R Sbjct: 1132 SRAK-----AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEAT 1186 Query: 542 ----PRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL--------ILKRLK 589 + TL K S+ E+ ++ +V QK +K E +E+ + + K Sbjct: 1187 LQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAK 1246 Query: 590 E--KRIERCLPEDIK--VTKEERHIVKPLYDRYRLVKQMLT-RASITPVLGSPSTK--RR 642 +++ R L + + TKEE ++ RL+ + RA + G S + + Sbjct: 1247 GNLEKMCRALEDQLSEIKTKEE--------EQQRLINDLTAQRARLQTESGEYSRQLDEK 1298 Query: 643 GQMLQPIIEGETA--HFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQ 700 ++ + G+ A EE+K + E+ + S L L+++ L + +E + Sbjct: 1299 DTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAK 1358 Query: 701 EKLALDLRLSSSRAASM-----PELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQK 755 +L + ++S A + +++ + KKKL + L++ EE N + A Sbjct: 1359 AELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASL 1418 Query: 756 E 756 E Sbjct: 1419 E 1419 Score = 35.8 bits (81), Expect = 0.16 Identities = 68/329 (20%), Positives = 144/329 (43%), Gaps = 46/329 (13%) Query: 475 QLVK---KLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKN 531 QL+K +L+ KI++ E+ E E +++ A + L+ E ++L+K I D + Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEIN---AELTAKKRKLE--DECSELKKDIDDLELTL 965 Query: 532 SDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILK-RLKE 590 + E + ++ +L E ++ + KEKK +EA + + + +E Sbjct: 966 AKVE-------KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018 Query: 591 KRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPII 650 ++ IK+ ++ + L ++ + ++ L RA + G + M I Sbjct: 1019 DKVNTLTKAKIKLEQQVDDLEGSL-EQEKKIRMDLERAK-RKLEGDLKLAQESTM---DI 1073 Query: 651 EGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLS 710 E + E++K++E + L S++ D +Q+Q ++ ++ +EE +E++ + R S Sbjct: 1074 ENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAE-RAS 1132 Query: 711 SSRA--------ASMPELLEQLWKA-----------RAEKKKLRKTLREFEEAFYQQNGR 751 ++A + E+ E+L +A + + + +K R+ EEA Q Sbjct: 1133 RAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEAT 1192 Query: 752 NA----QKEDRVPVL-EEYREYKKIKAKL 775 A + D V L E+ +++K KL Sbjct: 1193 AATLRKKHADSVAELGEQIDNLQRVKQKL 1221 Score = 31.6 bits (70), Expect = 3.0 Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 10/125 (8%) Query: 653 ETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSS 712 + A EE+K+E++ +L ++ +T +Q L+ +E + +K ++ + Sbjct: 1765 DAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKK---QIQKLEA 1821 Query: 713 RAASMPELLEQLWKARAEK-KKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKI 771 R + +E K E K LRK R+ +E YQ +EDR +L K+ Sbjct: 1822 RVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQ------TEEDRKNILRLQDLVDKL 1875 Query: 772 KAKLR 776 +AK++ Sbjct: 1876 QAKVK 1880 >gi|4758648 kinesin family member 5B [Homo sapiens] Length = 963 Score = 43.9 bits (102), Expect = 6e-04 Identities = 59/278 (21%), Positives = 113/278 (40%), Gaps = 24/278 (8%) Query: 516 ELTKLRKQIKDAKHK-NSDGEFVPQTRPRSNTLPKSFGSSLDHEDEEN-EDEPKVIQKEK 573 E+ KL KQ+ D + N + V + + + + S+ D++N + E +Q E Sbjct: 424 EIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLAST--RRDQDNMQAELNRLQAEN 481 Query: 574 KPSKEATLELILKRLKEKRI--ERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASIT 631 SKE E +L+ L+E + ++ E TKE + L + + + Sbjct: 482 DASKEEVKE-VLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL 540 Query: 632 PVLGSPSTKRRGQM----LQPIIEGETAHFFEEIKEEEEDGV-------------NLSSE 674 + + KR +M L+ + E A ++K+ E G+ + SE Sbjct: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600 Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734 + M+K Q++S+ S +EEN+++LA S A + L E L +K++L Sbjct: 601 VKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQL 660 Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIK 772 +++ E Q + E L + + ++K Sbjct: 661 EESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVK 698 >gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens] Length = 1790 Score = 43.9 bits (102), Expect = 6e-04 Identities = 61/249 (24%), Positives = 106/249 (42%), Gaps = 45/249 (18%) Query: 537 VPQTRPRSNTLP----KSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKR 592 +PQ R LP + +G + +EE E+E + +K KKP E ++E Sbjct: 1473 MPQYGSRRRLLPPAGQEEYGEVVGEAEEEYEEEEEEPKKIKKPKVE---------IREPS 1523 Query: 593 IERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQM-LQPIIE 651 E E++ VT E+ +P Y ++ RA I P++ K RG + I++ Sbjct: 1524 EE----EEVVVTIEKPPAAEPTYTTWK-------RARIFPMI---FKKVRGLADKRGIVD 1569 Query: 652 GETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQ---------VQSSLENSESDVEENQEK 702 E + ++EE++D + L+ + + ++ V+ + S E SE E E+ Sbjct: 1570 LEGEEWQRRLEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEE 1629 Query: 703 LALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTL-----REFEEAFYQQNGR--NAQK 755 + S +S PE E+ +E +K RK + R E + GR Q+ Sbjct: 1630 ESESETPSEEEESSTPE-SEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQE 1688 Query: 756 EDRVPVLEE 764 E + P +EE Sbjct: 1689 EQKEPKMEE 1697 Score = 32.3 bits (72), Expect = 1.8 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 4/58 (6%) Query: 97 EEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTEN 154 E E+ SS+D + +E+ +E SE E +E+ E E P E E S PE + TE+ Sbjct: 1602 ESEEESSSDYTEYSEEESEFSESETTEEESE--SETPSEEEESST--PESEESESTES 1655 >gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 [Homo sapiens] Length = 3259 Score = 43.9 bits (102), Expect = 6e-04 Identities = 141/742 (19%), Positives = 284/742 (38%), Gaps = 92/742 (12%) Query: 62 DVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEE 121 DV + +E+ +Q V+ I + E + NEE+ ++ ++ EQ+N LS EE Sbjct: 888 DVETLQQTIEEKDQQ--VTEISFSMTEKMVQL--NEEKFSLGVEIKTLKEQLNLLSRAEE 943 Query: 122 -EDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180 + E++E E+ + ++M Q+ E E +L + Sbjct: 944 AKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHE-------------FDLLKKENEQ 990 Query: 181 LERTIRAAV--EQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIAD-- 236 +R ++AA+ + L S ++ +L NL+ +S +I +++ Sbjct: 991 RKRKLQAALINRKELLQRVSRLEEELANLKDES-----------------KKEIPLSETE 1033 Query: 237 --DIINASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGC 294 ++ E+ K V S + E + + E E Q + LE + Sbjct: 1034 RGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL 1093 Query: 295 LEREEYLLFDSDKLSHLI---LDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLD 351 +++ L D L+ + + I + ++ G SV + E +S P Sbjct: 1094 VKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPC-- 1151 Query: 352 LKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRM 411 + W+ P ++ K + L+++ E+ K QE S +A L +A Sbjct: 1152 ---TGSSEHWK-------PELEEKILALEKEKEQ---LQKKLQEALTSRKAILK-KAQEK 1197 Query: 412 NHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEK----LDSSSKALSFTRIRRS---SFSSK 464 H EE L + D+ + Q + K + + L ++R S S Sbjct: 1198 ERHLREE-----LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQI-QVRESIDGKLPST 1251 Query: 465 DEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQI 524 D++ + L + L K Q Q E N P + + + L+ T + +++ Q+ Sbjct: 1252 DQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQL 1311 Query: 525 KDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATL--E 582 K+ + + + E + ++ L K +++ N+ + I+ K S EA + E Sbjct: 1312 KEIEAEKVELEL--KVSSTTSELTKKSEEVFQLQEQINKQGLE-IESLKTVSHEAEVHAE 1368 Query: 583 LILKRLKEKRIERCLPEDI-----KVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSP 637 + ++L+ +++ E + K+ + ++ I K D L Q+ + + + + Sbjct: 1369 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE 1428 Query: 638 STKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697 ++ + +I+ + KE +E L EL +M + ++ E S + + Sbjct: 1429 IIEQ-----EDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIG---EESRAK-Q 1479 Query: 698 ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKED 757 + Q KL L L E+L AR ++L K+L + E QN Sbjct: 1480 QIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLG 1539 Query: 758 RVPVLEEYREYKKIKAKLRLLE 779 R+ +L+E R+ + LLE Sbjct: 1540 RLALLQEERDKLITEMDRSLLE 1561 Score = 43.5 bits (101), Expect = 8e-04 Identities = 136/752 (18%), Positives = 287/752 (38%), Gaps = 121/752 (16%) Query: 71 EDMKEQEIVSRIMAGLLENYYEFFENE--EEDFS---------SNDLSSITEQVNELSEE 119 E +Q+I ++ A L+ EN+ +E+ S + L+ + QV+ ++ Sbjct: 1474 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS--AQN 1531 Query: 120 EEEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTD 179 +E+D L + L EE + +M ++LE+ S++++ + L T+ Sbjct: 1532 KEKDTVLGRLALLQEERDKLITEMDR--------SLLENQSLSSSCESLK--LALEGLTE 1581 Query: 180 ILERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVV---------CNNEAESIHCDGEGSNN 230 E+ ++ + S + K+ + Q +NEAE I E Sbjct: 1582 DKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQ 1641 Query: 231 QIDIADDIINASESNR-DCSKPVASTNLDNEAMQ----------QDCVFENEENTQSVGI 279 + + ++E+N+ + K + + E M+ Q + E EE + Sbjct: 1642 EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRA 1701 Query: 280 LLEPCSDRGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLN-ANTESEVPGGQSVGV 338 + P GD+ C+E L+ ++S +L E E + + Sbjct: 1702 EVHPA---GDTAKECMET-------------LLSSNASMKEELERVKMEYETLSKKFQSL 1745 Query: 339 QGEAACVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSE 398 E +S DLK+ +G+ + + D +T ++ +G + P E E Sbjct: 1746 MSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQT-NVTEEGTQSIPG-----ETEE 1799 Query: 399 SGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRR 458 +S + P + P +S + +L ++L L + + Sbjct: 1800 QDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKN 1859 Query: 459 SSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELT 518 FS E ++ Q+ K +++ +E+ + N ++ + ++ +T Sbjct: 1860 KEFSQTLENEKNTLLSQISTK-DGELKMLQEEVTKMN---------LLNQQIQEELSRVT 1909 Query: 519 KLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPK--VIQKEKKPS 576 KL++ ++ K + N L + GS ++ + + + K +++ E K Sbjct: 1910 KLKETAEEEKDDLEERLM--------NQLAELNGSIGNYCQDVTDAQIKNELLESEMKNL 1961 Query: 577 KEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGS 636 K+ EL E+ ++ + E KV E R K+ L + I Sbjct: 1962 KKCVSEL------EEEKQQLVKEKTKVESEIR-------------KEYLEK--IQGAQKE 2000 Query: 637 PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDV 696 P K + LQ +++ + +E+K+ ++D + ++ + +T ++ S+ D+ Sbjct: 2001 PGNKSHAKELQELLKEKQ----QEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL 2056 Query: 697 EENQEKLALDL---RLSSSRAASMPELLE----QLWKARAEKKKLRKTLREFEEAFYQQN 749 E +E LA + + + + AS LL+ + + A+ KL+K L+ +E+ Q Sbjct: 2057 EITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQ- 2115 Query: 750 GRNAQKEDRVPVLEEYREYKKIKAKLRLLEVL 781 QK++ + E E K +K K + E L Sbjct: 2116 --MKQKDEDLERRLEQAEEKHLKEKKNMQEKL 2145 Score = 40.4 bits (93), Expect = 0.006 Identities = 63/325 (19%), Positives = 127/325 (39%), Gaps = 53/325 (16%) Query: 469 EDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAK 528 E R Q+ +KLQ + +E + ++ + S + +L K + D + Sbjct: 1474 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGT---------IERLTKSLADVE 1524 Query: 529 HKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRL 588 + S Q + + L + + + E + +++ + S +L+L L+ L Sbjct: 1525 SQVS-----AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGL 1579 Query: 589 KE------KRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRR 642 E K IE I + E + K L Y ++ Q S Sbjct: 1580 TEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVS-----------NE 1628 Query: 643 GQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEK 702 + +Q H E +++E+++ L +L + + L+ +E ++EE +EK Sbjct: 1629 AERIQ--------HVVEAVRQEKQE---LYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677 Query: 703 LALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVL 762 + + + S+ + EL E+ + RAE T +E E N ++ +RV + Sbjct: 1678 MR---KFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM- 1733 Query: 763 EEYREYKKIKAKLRLLEVLISKQDS 787 EY+ + K + L+S++DS Sbjct: 1734 ----EYETLSKK---FQSLMSEKDS 1751 Score = 37.0 bits (84), Expect = 0.071 Identities = 79/368 (21%), Positives = 152/368 (41%), Gaps = 31/368 (8%) Query: 410 RMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDE--- 466 ++N LE + +SH + +S + +KL+SS ++ R DE Sbjct: 1345 QINKQGLEIESLKTVSHEAEVHAESLQ-----QKLESSQLQIAGLEHLRELQPKLDELQK 1399 Query: 467 ---KREDRTPY---QLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKL 520 K+E+ Y QL +K + E E+E K ++ + K + + +L Sbjct: 1400 LISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK--EHDERIKQL 1457 Query: 521 RKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEAT 580 + ++ + K K E ++R + K + + ++ E+ K +Q+E ++ T Sbjct: 1458 QVELCEMKQKPE--EIGEESRAKQQIQRKLQAALISRKEALKEN--KSLQEELSLAR-GT 1512 Query: 581 LELILKRLKEKRIERCLPEDIKVT--------KEERHIVKPLYDRYRLVKQMLTRASITP 632 +E + K L + + K T +EER + DR L Q L+ + + Sbjct: 1513 IERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESL 1572 Query: 633 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692 L + L IE + E E +E L E +L++ V + E Sbjct: 1573 KLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERI 1632 Query: 693 ESDVEE-NQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGR 751 + VE QEK L +L S+ A + E +QL +A E +++++ +R+F ++ Q+ Sbjct: 1633 QHVVEAVRQEKQELYGKLRSTEA-NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILE 1691 Query: 752 NAQKEDRV 759 ++ DR+ Sbjct: 1692 LEEENDRL 1699 Score = 35.8 bits (81), Expect = 0.16 Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 16/146 (10%) Query: 72 DMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEE 131 +MKEQ+I+S LL E + + I E N LS+EEEE+ LE E Sbjct: 2378 NMKEQKIIS-----LLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLE---E 2429 Query: 132 LPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQ 191 ++ +K+N + E ++ ENI + + + + +S L D + + E+ Sbjct: 2430 ENKKAVDKTNQLMETLKTIKKENIQQKAQL---DSFVKSMSSLQNDRDRIVGDYQQLEER 2486 Query: 192 HLFDLQSSIDHDLKNLQQQSVVCNNE 217 HL SI + L Q++ NN+ Sbjct: 2487 HL-----SIILEKDQLIQEAAAENNK 2507 Score = 33.1 bits (74), Expect = 1.0 Identities = 41/142 (28%), Positives = 71/142 (50%), Gaps = 19/142 (13%) Query: 650 IEGETAHFFEEIKEEEEDGVNLS-SELGDMLKTAVQVQSSLENSESDVEENQEKLALDLR 708 IE ++ E+ + E D V L SE ++++ +QS L+N ES+V E E++ Sbjct: 803 IEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRS---LQSQLQNKESEVLEGAERVR---H 856 Query: 709 LSS-----SRAASMPEL-LEQLWKARAEKKKLRKTLRE-FEEAFYQQNGRNAQKEDRVPV 761 +SS S+A S EL + ++ + EKK+ +TL++ EE Q + +++ Sbjct: 857 ISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQ 916 Query: 762 LEEYR-----EYKKIKAKLRLL 778 L E + E K +K +L LL Sbjct: 917 LNEEKFSLGVEIKTLKEQLNLL 938 Score = 31.6 bits (70), Expect = 3.0 Identities = 39/164 (23%), Positives = 66/164 (40%), Gaps = 25/164 (15%) Query: 69 DVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEH 128 ++ +KEQ +++R LL F N E+ S + L + +Q+ +DE+L H Sbjct: 2767 ELAQLKEQGLLNRERDALLSET-AFSMNSTEENSLSHLEKLNQQLLS------KDEQLLH 2819 Query: 129 IEELPEEGAEKSNDMPEVVQLRMTE-----NILES--NSVTATSTHISPISILPASTDIL 181 + E+ + + + E N LE S + S PA L Sbjct: 2820 LSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSL 2879 Query: 182 ERTIRAAVEQHLFDLQSSIDH---DLKNLQQQSVVCNNEAESIH 222 ++ + + LQ+ D +LKNLQQQ + N E +H Sbjct: 2880 KKAMSS--------LQNDRDRLLKELKNLQQQYLQINQEITELH 2915 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.129 0.356 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 30,529,093 Number of Sequences: 37866 Number of extensions: 1492826 Number of successful extensions: 11130 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 113 Number of HSP's successfully gapped in prelim test: 551 Number of HSP's that attempted gapping in prelim test: 8259 Number of HSP's gapped (non-prelim): 2614 length of query: 791 length of database: 18,247,518 effective HSP length: 110 effective length of query: 681 effective length of database: 14,082,258 effective search space: 9590017698 effective search space used: 9590017698 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.