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Search of human proteins with 156142192
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo
sapiens]
(791 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens] 1565 0.0
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens] 1506 0.0
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens] 1491 0.0
gi|56119110 family with sequence similarity 13, member A1 isofor... 484 e-136
gi|62865869 family with sequence similarity 13, member A1 isofor... 427 e-119
gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens] 242 9e-64
gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo sapi... 242 9e-64
gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens] 137 3e-32
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 55 3e-07
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 55 3e-07
gi|208022687 GTPase regulator associated with the focal adhesion... 50 8e-06
gi|7662208 GTPase regulator associated with the focal adhesion k... 50 8e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 49 2e-05
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa... 49 2e-05
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa... 49 2e-05
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa... 49 2e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 49 2e-05
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 49 2e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 48 4e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 47 5e-05
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens] 46 1e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 46 2e-04
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 45 2e-04
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens] 45 3e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 44 4e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 44 4e-04
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 44 4e-04
gi|4758648 kinesin family member 5B [Homo sapiens] 44 6e-04
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 44 6e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 44 6e-04
>gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]
Length = 791
Score = 1565 bits (4053), Expect = 0.0
Identities = 791/791 (100%), Positives = 791/791 (100%)
Query: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60
MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG
Sbjct: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60
Query: 61 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120
PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE
Sbjct: 61 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120
Query: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI
Sbjct: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
Query: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240
LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN
Sbjct: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240
Query: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300
ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY
Sbjct: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300
Query: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360
LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK
Sbjct: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360
Query: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420
WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC
Sbjct: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420
Query: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480
PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL
Sbjct: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480
Query: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540
QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT
Sbjct: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540
Query: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600
RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED
Sbjct: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600
Query: 601 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 660
IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE
Sbjct: 601 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 660
Query: 661 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 720
IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL
Sbjct: 661 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 720
Query: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780
LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV
Sbjct: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780
Query: 781 LISKQDSSKSI 791
LISKQDSSKSI
Sbjct: 781 LISKQDSSKSI 791
>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
Length = 887
Score = 1506 bits (3900), Expect = 0.0
Identities = 769/791 (97%), Positives = 769/791 (97%), Gaps = 22/791 (2%)
Query: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60
MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG
Sbjct: 119 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 178
Query: 61 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120
PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE
Sbjct: 179 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 238
Query: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI
Sbjct: 239 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 298
Query: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240
LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN
Sbjct: 299 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 358
Query: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300
ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY
Sbjct: 359 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 418
Query: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360
LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK
Sbjct: 419 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 478
Query: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420
WE EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC
Sbjct: 479 WE----------------------EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 516
Query: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480
PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL
Sbjct: 517 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 576
Query: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540
QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT
Sbjct: 577 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 636
Query: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600
RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED
Sbjct: 637 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 696
Query: 601 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 660
IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE
Sbjct: 697 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 756
Query: 661 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 720
IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL
Sbjct: 757 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 816
Query: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780
LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV
Sbjct: 817 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 876
Query: 781 LISKQDSSKSI 791
LISKQDSSKSI
Sbjct: 877 LISKQDSSKSI 887
>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
Length = 915
Score = 1491 bits (3861), Expect = 0.0
Identities = 769/819 (93%), Positives = 769/819 (93%), Gaps = 50/819 (6%)
Query: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60
MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG
Sbjct: 119 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 178
Query: 61 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120
PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE
Sbjct: 179 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 238
Query: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI
Sbjct: 239 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 298
Query: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240
LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN
Sbjct: 299 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 358
Query: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300
ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY
Sbjct: 359 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 418
Query: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360
LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK
Sbjct: 419 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 478
Query: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420
W EEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC
Sbjct: 479 W----------------------EEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 516
Query: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480
PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL
Sbjct: 517 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 576
Query: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540
QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT
Sbjct: 577 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 636
Query: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600
RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED
Sbjct: 637 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 696
Query: 601 IK----------------------------VTKEERHIVKPLYDRYRLVKQMLTRASITP 632
IK VTKEERHIVKPLYDRYRLVKQMLTRASITP
Sbjct: 697 IKKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITP 756
Query: 633 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692
VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS
Sbjct: 757 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 816
Query: 693 ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN 752
ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN
Sbjct: 817 ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN 876
Query: 753 AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 791
AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI
Sbjct: 877 AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 915
>gi|56119110 family with sequence similarity 13, member A1 isoform a
[Homo sapiens]
Length = 1023
Score = 484 bits (1247), Expect = e-136
Identities = 348/925 (37%), Positives = 492/925 (53%), Gaps = 173/925 (18%)
Query: 1 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVF 59
+QL QD N+ + LR L+++LP +Y LLK+LC+FL VA HH + + ++LA VF
Sbjct: 138 IQLFQDGRNDVQES-SLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVF 196
Query: 60 GPDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENE------------------EEDF 101
GP+ FH+ +E MKEQ++ ++IMA +LENY FE E +E +
Sbjct: 197 GPNCFHVPPGLEGMKEQDLCNKIMAKILENYNTLFEVEYTENDHLRCENLARLIIVKEVY 256
Query: 102 SSNDL------------------SSITEQVNELSEEEEEDEKLEHIEELPEEGAEKSNDM 143
N L + I + +E S + + E + +P+ S
Sbjct: 257 YKNSLPILLTRGLERDMPKPPPKTKIPKSRSEGSIQAHRVLQPELSDGIPQLSLRLSYRK 316
Query: 144 PEVVQLRMTENILESNSVTAT------------STHISPISILPASTDILERTIRAAVEQ 191
+ + E + + V ++ S H+ +S + A+ ++LERTIR+AVEQ
Sbjct: 317 ACLEDMNSAEGAISAKLVPSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQ 376
Query: 192 HLFDL-----QSSIDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID----- 233
HLFD+ QSS D + L S + E H +G N+ +
Sbjct: 377 HLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGF 436
Query: 234 --IADDIINASESNR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQS 276
+ D I+N E + + SKP +ST L QD + E+ +T+S
Sbjct: 437 NHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRS 496
Query: 277 VGIL----LEPCSD--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEV 330
E SD +G+ +DG + F+S + KI + + ++++
Sbjct: 497 HERTGPDDFEWMSDERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQ 543
Query: 331 PGGQSVGVQGEAACVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAF 390
Q G Q E+ +P DL + D WE EP PAF
Sbjct: 544 QRNQDAGDQEESFVSEVPQSDLTALCDEKNWE----------------------EPIPAF 581
Query: 391 KSWQ-EDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSK 449
SWQ E+S+S EA LSPQAGR+ L+ED P+LS R +GQS+++L D E S
Sbjct: 582 SSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPN 641
Query: 450 ALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAA 506
+ SF R R SS S D+++ED TP QL +++Q KKIR+FE++FE E+ +PS+SD AA
Sbjct: 642 SHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAA 701
Query: 507 NPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEP 566
NP+VLKW +L K R+Q+K++K K S+ + P+ R RSNTLPKSFGS L+ EDE+ ++
Sbjct: 702 NPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQE-- 759
Query: 567 KVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK------------------------ 602
++ K KPS EATLE I ++L+EKR E PEDIK
Sbjct: 760 -LVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESI 818
Query: 603 ----VTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFF 658
VTK ER ++KPLYDRYRLVKQ+L+RA+ P++GSPS+KRR +LQPIIEGETA FF
Sbjct: 819 HGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFF 878
Query: 659 EEIKEEEE---DGVNLSSELGDMLKTAVQVQSSLENSESDVE--------ENQEKLALDL 707
+EIKEEEE D N+ + LKT + L+ E D + + K + D
Sbjct: 879 KEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDT 938
Query: 708 RLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYRE 767
LS+ AAS+PELLE L + R EKK++RK LR+FE+ F++QNGRN QKEDR P+ EEY E
Sbjct: 939 GLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSE 998
Query: 768 YKKIKAKLRLLEVLISKQDS-SKSI 791
YK IKAKLRLLEVLISK+D+ SKS+
Sbjct: 999 YKHIKAKLRLLEVLISKRDTDSKSM 1023
>gi|62865869 family with sequence similarity 13, member A1 isoform b
[Homo sapiens]
Length = 697
Score = 427 bits (1097), Expect = e-119
Identities = 295/732 (40%), Positives = 407/732 (55%), Gaps = 123/732 (16%)
Query: 145 EVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDL-----QSS 199
E++ L+ ++ S S H+ +S + A+ ++LERTIR+AVEQHLFD+ QSS
Sbjct: 4 EIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSS 63
Query: 200 IDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID-------IADDIINASES 244
D + L S + E H +G N+ + + D I+N E
Sbjct: 64 EDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEV 123
Query: 245 NR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQSVGIL----LEPCS 285
+ + SKP +ST L QD + E+ +T+S E S
Sbjct: 124 EKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMS 183
Query: 286 D--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAA 343
D +G+ +DG + F+S + KI + + ++++ Q G Q E+
Sbjct: 184 DERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQQRNQDAGDQEESF 230
Query: 344 CVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQ-EDSESGEA 402
+P DL + D WE EP PAF SWQ E+S+S EA
Sbjct: 231 VSEVPQSDLTALCDEKNWE----------------------EPIPAFSSWQRENSDSDEA 268
Query: 403 QLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS 462
LSPQAGR+ L+ED P+LS R +GQS+++L D E S + SF R R SS
Sbjct: 269 HLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLG 328
Query: 463 SKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTK 519
S D+++ED TP QL +++Q KKIR+FE++FE E+ +PS+SD AANP+VLKW +L K
Sbjct: 329 SYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAK 388
Query: 520 LRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEA 579
R+Q+K++K K S+ + P+ R RSNTLPKSFGS L+ EDE+ ++ ++ K KPS EA
Sbjct: 389 FRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVDKAIKPSVEA 445
Query: 580 TLELILKRLKEKRIERCLPEDIK----------------------------VTKEERHIV 611
TLE I ++L+EKR E PEDIK VTK ER ++
Sbjct: 446 TLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVM 505
Query: 612 KPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEE---DG 668
KPLYDRYRLVKQ+L+RA+ P++GSPS+KRR +LQPIIEGETA FF+EIKEEEE D
Sbjct: 506 KPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDD 565
Query: 669 VNLSSELGDMLKTAVQVQSSLENSESDVE--------ENQEKLALDLRLSSSRAASMPEL 720
N+ + LKT + L+ E D + + K + D LS+ AAS+PEL
Sbjct: 566 SNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPEL 625
Query: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780
LE L + R EKK++RK LR+FE+ F++QNGRN QKEDR P+ EEY EYK IKAKLRLLEV
Sbjct: 626 LEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEV 685
Query: 781 LISKQDS-SKSI 791
LISK+D+ SKS+
Sbjct: 686 LISKRDTDSKSM 697
>gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens]
Length = 585
Score = 242 bits (618), Expect = 9e-64
Identities = 164/424 (38%), Positives = 238/424 (56%), Gaps = 47/424 (11%)
Query: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440
D +P P K Q +++S L S R+ +H + D P+LS R F QSQRF D
Sbjct: 195 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 253
Query: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497
PE S F R SS S + +E +T QL K +Q +KIR+FEE+FE+E+
Sbjct: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313
Query: 498 KPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NTLPKSF 551
+PS+ D +NP+VLKWM +L K RKQ+K+ K K S+ + P+ PR+ T+P+
Sbjct: 314 RPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPREN 373
Query: 552 GSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIV 611
G +P+ E S E T + L LKE+R + ED KVTK++++++
Sbjct: 374 G------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLI 421
Query: 612 KPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEED 667
KPLYDRYR++KQ+L+ S+ P + S + +G QP + +H D
Sbjct: 422 KPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGD 474
Query: 668 GVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKA 727
+ S+E V++ L + + +V+ L +S+ A+MP LL+ L +
Sbjct: 475 HLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRET 521
Query: 728 RAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787
RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD
Sbjct: 522 RADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDV 581
Query: 788 SKSI 791
+K+I
Sbjct: 582 AKTI 585
>gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo
sapiens]
Length = 502
Score = 242 bits (618), Expect = 9e-64
Identities = 164/424 (38%), Positives = 238/424 (56%), Gaps = 47/424 (11%)
Query: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440
D +P P K Q +++S L S R+ +H + D P+LS R F QSQRF D
Sbjct: 112 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 170
Query: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497
PE S F R SS S + +E +T QL K +Q +KIR+FEE+FE+E+
Sbjct: 171 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 230
Query: 498 KPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NTLPKSF 551
+PS+ D +NP+VLKWM +L K RKQ+K+ K K S+ + P+ PR+ T+P+
Sbjct: 231 RPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPREN 290
Query: 552 GSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIV 611
G +P+ E S E T + L LKE+R + ED KVTK++++++
Sbjct: 291 G------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLI 338
Query: 612 KPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEED 667
KPLYDRYR++KQ+L+ S+ P + S + +G QP + +H D
Sbjct: 339 KPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGD 391
Query: 668 GVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKA 727
+ S+E V++ L + + +V+ L +S+ A+MP LL+ L +
Sbjct: 392 HLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRET 438
Query: 728 RAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787
RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD
Sbjct: 439 RADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDV 498
Query: 788 SKSI 791
+K+I
Sbjct: 499 AKTI 502
>gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens]
Length = 487
Score = 137 bits (346), Expect = 3e-32
Identities = 89/227 (39%), Positives = 134/227 (59%), Gaps = 28/227 (12%)
Query: 573 KKPSKEATLELILKRLKEK--RIERCLPEDIK--VTKEERHIVKPLYDRYRLVKQMLTRA 628
K+P L ++ LK K + E ++ K VTK++++++KPLYDRYR++KQ+L+
Sbjct: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTP 340
Query: 629 SITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQ 684
S+ P + S + +G QP + +H D + S+E
Sbjct: 341 SLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGDHLTYSNE-------TEP 386
Query: 685 VQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEA 744
V++ L + + +V+ L +S+ A+MP LL+ L + RA+KK+LRK LREFEE
Sbjct: 387 VRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQ 440
Query: 745 FYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 791
F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD +K+I
Sbjct: 441 FFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 487
Score = 78.2 bits (191), Expect = 3e-14
Identities = 71/239 (29%), Positives = 109/239 (45%), Gaps = 31/239 (12%)
Query: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440
D +P P K Q +++S L S R+ +H + D P+LS R F QSQRF D
Sbjct: 195 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 253
Query: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497
PE S F R SS S + +E +T QL K +Q +KIR+FEE+FE+E+
Sbjct: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313
Query: 498 KPSYSD------IAANPKVLKWMTELTKLRKQIKDAKHKNSD---GEFVPQTRPRSNTLP 548
+ + D + +++K + L I++ + + D G P ++ LP
Sbjct: 314 RVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 373
Query: 549 KSFGSSLDHEDEENEDEP--KVIQKEKKPSK----------EATLELILKRLKEKRIER 595
DH NE EP ++ EKK K EAT+ ++L L+E R ++
Sbjct: 374 VG-----DHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK 427
Score = 32.0 bits (71), Expect = 2.3
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 4/69 (5%)
Query: 436 RFLHDPEKLDSSSKALSFTRIRRSSFSSK-DEKREDRTPYQLVKKLQKKIRQFEEQFERE 494
R L EK + ALS + + ++ D RE R K+L+K +R+FEEQF ++
Sbjct: 388 RALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK---KRLRKALREFEEQFFKQ 444
Query: 495 RNSKPSYSD 503
P D
Sbjct: 445 TGRSPQKED 453
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 54.7 bits (130), Expect = 3e-07
Identities = 65/295 (22%), Positives = 128/295 (43%), Gaps = 29/295 (9%)
Query: 442 EKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSY 501
EK+ +K ++ +S+ S + K +++ KKL K + EE +E+ ++
Sbjct: 342 EKIHEDTKEIN----EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEEN--KEKFTQLDL 395
Query: 502 SDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVP--------QTRPRSNTLPKSFGS 553
D+ K+ ++ KL KQ++ K K + + +P +T R+N L K
Sbjct: 396 EDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEK 455
Query: 554 S---LDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHI 610
L + + E + +QKEK+ S+E L K + E R + + V + E I
Sbjct: 456 EEKKLKEVMDSLKQETQGLQKEKE-SREKELMGFSKSVNEARSK------MDVAQSELDI 508
Query: 611 VKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVN 670
R+ LT+A + S + K R ++ I EG+ +E+KE+E++
Sbjct: 509 Y---LSRHNTAVSQLTKAKEALIAASETLKERKAAIRDI-EGKLPQTEQELKEKEKELQK 564
Query: 671 LSSELGDMLKTAVQVQSSLENSESDVEENQEK-LALDLRLSSSRAASMPELLEQL 724
L+ E + + +E ++S + N+ + LD + ++ +P + +L
Sbjct: 565 LTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRL 619
Score = 32.7 bits (73), Expect = 1.3
Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 12/146 (8%)
Query: 650 IEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLA-LDLR 708
+E + E+ KE E LS+E+ K + L +EEN+EK LDL
Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLE 396
Query: 709 LSSSRAASMPELLEQLWKARAEKKKLRKTL---REFEEAFYQQNGRNAQKEDRVPVLEEY 765
R E+L A ++ KKL K L +E E F ++ +
Sbjct: 397 DVQVR--------EKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNA 448
Query: 766 REYKKIKAKLRLLEVLISKQDSSKSI 791
E +K K + +L EV+ S + ++ +
Sbjct: 449 LEKEKEKEEKKLKEVMDSLKQETQGL 474
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 54.7 bits (130), Expect = 3e-07
Identities = 65/295 (22%), Positives = 128/295 (43%), Gaps = 29/295 (9%)
Query: 442 EKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSY 501
EK+ +K ++ +S+ S + K +++ KKL K + EE +E+ ++
Sbjct: 342 EKIHEDTKEIN----EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEEN--KEKFTQLDL 395
Query: 502 SDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVP--------QTRPRSNTLPKSFGS 553
D+ K+ ++ KL KQ++ K K + + +P +T R+N L K
Sbjct: 396 EDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEK 455
Query: 554 S---LDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHI 610
L + + E + +QKEK+ S+E L K + E R + + V + E I
Sbjct: 456 EEKKLKEVMDSLKQETQGLQKEKE-SREKELMGFSKSVNEARSK------MDVAQSELDI 508
Query: 611 VKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVN 670
R+ LT+A + S + K R ++ I EG+ +E+KE+E++
Sbjct: 509 Y---LSRHNTAVSQLTKAKEALIAASETLKERKAAIRDI-EGKLPQTEQELKEKEKELQK 564
Query: 671 LSSELGDMLKTAVQVQSSLENSESDVEENQEK-LALDLRLSSSRAASMPELLEQL 724
L+ E + + +E ++S + N+ + LD + ++ +P + +L
Sbjct: 565 LTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRL 619
Score = 32.7 bits (73), Expect = 1.3
Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 12/146 (8%)
Query: 650 IEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLA-LDLR 708
+E + E+ KE E LS+E+ K + L +EEN+EK LDL
Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLE 396
Query: 709 LSSSRAASMPELLEQLWKARAEKKKLRKTL---REFEEAFYQQNGRNAQKEDRVPVLEEY 765
R E+L A ++ KKL K L +E E F ++ +
Sbjct: 397 DVQVR--------EKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNA 448
Query: 766 REYKKIKAKLRLLEVLISKQDSSKSI 791
E +K K + +L EV+ S + ++ +
Sbjct: 449 LEKEKEKEEKKLKEVMDSLKQETQGL 474
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 50.1 bits (118), Expect = 8e-06
Identities = 41/173 (23%), Positives = 75/173 (43%), Gaps = 21/173 (12%)
Query: 9 NEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEE-IWSANSLAAVFGPDVFHIY 67
N++ ++ L+ +LP N +L+ L LANVA++H++ + + +L VFGP +
Sbjct: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540
Query: 68 TD----VEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEED 123
+ + D+K Q IV I+ EN E+ F++ +T LS ++ D
Sbjct: 541 EETVAAIMDIKFQNIVIEIL----------IENHEKIFNTVPDMPLTNAQLHLSRKKSSD 590
Query: 124 EKLEHIEELP------EEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISP 170
K E P + EK ++ + NS+ +S+ + P
Sbjct: 591 SKPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQP 643
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 50.1 bits (118), Expect = 8e-06
Identities = 41/173 (23%), Positives = 75/173 (43%), Gaps = 21/173 (12%)
Query: 9 NEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEE-IWSANSLAAVFGPDVFHIY 67
N++ ++ L+ +LP N +L+ L LANVA++H++ + + +L VFGP +
Sbjct: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540
Query: 68 TD----VEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEED 123
+ + D+K Q IV I+ EN E+ F++ +T LS ++ D
Sbjct: 541 EETVAAIMDIKFQNIVIEIL----------IENHEKIFNTVPDMPLTNAQLHLSRKKSSD 590
Query: 124 EKLEHIEELP------EEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISP 170
K E P + EK ++ + NS+ +S+ + P
Sbjct: 591 SKPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQP 643
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 48.9 bits (115), Expect = 2e-05
Identities = 62/314 (19%), Positives = 138/314 (43%), Gaps = 20/314 (6%)
Query: 477 VKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQI-----KDAKHKN 531
+++ ++KIR+ EE+ R+ + + + W E K+R+Q K+ K +
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKIRE 442
Query: 532 SDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEK 591
+ + Q + R + + +++ E E K+ ++E+K ++ E ++ +EK
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ---EEKIREQEEK 499
Query: 592 --RIERCLPEDIKVTKEE-RHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQP 648
R E + E K+ +EE R + ++ + +++ + K R Q +
Sbjct: 500 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559
Query: 649 IIEGETAHFFEE-IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDL 707
+ E H EE I+E+EE ++ + + + + + E +E +EK+
Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE 619
Query: 708 RLSSSRAASMPELLEQLW----KARAEKKKLRKT---LREFEEAFYQQNGRNAQKEDRVP 760
+ M E E++ K R ++KK+R+ +RE EE +Q + ++E+++
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 679
Query: 761 VLEEYREYKKIKAK 774
EE + ++ K +
Sbjct: 680 EQEEKMQEQEEKMR 693
Score = 47.0 bits (110), Expect = 7e-05
Identities = 52/339 (15%), Positives = 147/339 (43%), Gaps = 26/339 (7%)
Query: 455 RIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQ-FERERNSKPSYSDIAANPKVLKW 513
+IR ++++ + R +++ + ++K+R+ EE +E+E + + + ++
Sbjct: 383 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 442
Query: 514 MTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSS---LDHEDEENEDEPKVIQ 570
+ E +++I++ + K + E + + R K + + E++ E E K+ +
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWR 502
Query: 571 KEKKPSKEATLELILKRLKEKRI-----------------ERCLPEDIKVTKEERHIVKP 613
+E+K ++ + KR +++ + E+ ++ K+ K+E + +
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562
Query: 614 ---LYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGE--TAHFFEEIKEEEEDG 668
++D+ +++ + ++ + + I E E T E++ E+EE
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 622
Query: 669 VNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKAR 728
++ + + + + + E + E +EK+ + + M E E++ +
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682
Query: 729 AEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYRE 767
+ ++ + +R EE ++Q R Q+E+++ +E+ E
Sbjct: 683 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721
Score = 39.3 bits (90), Expect = 0.014
Identities = 47/236 (19%), Positives = 109/236 (46%), Gaps = 23/236 (9%)
Query: 559 DEENEDEPKVIQKEKK--PSKEATLELILKRLKEK--RIERCLPEDIKVTKEERHIVKPL 614
DEE +++ +Q++ + S+++ ++L +K LK K R + LP+ ++ E H+ K L
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKEL 335
Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674
++ + + L ++ + + I E E E+I+E+EE +
Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE-----EKIQEQEE-------K 383
Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
+ + + + + + E + E +EK+ + + M E +W+ + ++L
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 443
Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYK----KIKAKLRLLEVLISKQD 786
+ + E E+ Q+ R Q+E+++ E+ +E + + + K+R E I +Q+
Sbjct: 444 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497
Score = 31.2 bits (69), Expect = 3.9
Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 66 IYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEE---- 121
++ E ++EQE R + E + +EE + + EQ ++ E+EE
Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE-EKMCEQEEKMQEQEEKMRR 638
Query: 122 EDEKLEHIEELPEEGAEKSNDMPEVVQ 148
++EK+ E+ E EK + E++Q
Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQ 665
>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
sapiens]
Length = 653
Score = 48.5 bits (114), Expect = 2e-05
Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 8/98 (8%)
Query: 8 NNEDEFG-RKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFH 65
+ E+E G ++L ++ LP VNY+LLK++CRFL V S+ S +LA VFGP++
Sbjct: 144 SKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI-- 201
Query: 66 IYTDVED----MKEQEIVSRIMAGLLENYYEFFENEEE 99
+ VED M+ +V ++M+ ++ + F + E
Sbjct: 202 LRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAE 239
>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
sapiens]
Length = 655
Score = 48.5 bits (114), Expect = 2e-05
Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 8/98 (8%)
Query: 8 NNEDEFG-RKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFH 65
+ E+E G ++L ++ LP VNY+LLK++CRFL V S+ S +LA VFGP++
Sbjct: 146 SKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI-- 203
Query: 66 IYTDVED----MKEQEIVSRIMAGLLENYYEFFENEEE 99
+ VED M+ +V ++M+ ++ + F + E
Sbjct: 204 LRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAE 241
>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
sapiens]
Length = 748
Score = 48.5 bits (114), Expect = 2e-05
Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 8/98 (8%)
Query: 8 NNEDEFG-RKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFH 65
+ E+E G ++L ++ LP VNY+LLK++CRFL V S+ S +LA VFGP++
Sbjct: 239 SKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI-- 296
Query: 66 IYTDVED----MKEQEIVSRIMAGLLENYYEFFENEEE 99
+ VED M+ +V ++M+ ++ + F + E
Sbjct: 297 LRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAE 334
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/278 (22%), Positives = 112/278 (40%), Gaps = 34/278 (12%)
Query: 426 HRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS---SKDEKREDRTPYQLVKKLQK 482
HRS +S+ D + S K S +R RR S S S+D++++ R + +++++
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 392
Query: 483 KIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRP 542
K R+ E + E+ER K+ + K+K+ D E + R
Sbjct: 393 KDREKEREREKERE-------------------------KEKERGKNKDRDKER-EKDRE 426
Query: 543 RSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK 602
+ + +HE + ++++ K KEK+ K+ + E+ KR K+K+ R P
Sbjct: 427 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTPPRSYN 485
Query: 603 VTKEERHIVKPLYDRYRLVKQMLTRASIT---PVLGSPSTKRRGQMLQPIIEGETAHFFE 659
++ R + R R S T SPS + R + E E H E
Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK-DKKREKERDHISE 544
Query: 660 EIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
+ E + SS D + + +SL+ E + E
Sbjct: 545 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 582
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/278 (22%), Positives = 112/278 (40%), Gaps = 34/278 (12%)
Query: 426 HRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS---SKDEKREDRTPYQLVKKLQK 482
HRS +S+ D + S K S +R RR S S S+D++++ R + +++++
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 276
Query: 483 KIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRP 542
K R+ E + E+ER K+ + K+K+ D E + R
Sbjct: 277 KDREKEREREKERE-------------------------KEKERGKNKDRDKER-EKDRE 310
Query: 543 RSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK 602
+ + +HE + ++++ K KEK+ K+ + E+ KR K+K+ R P
Sbjct: 311 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTPPRSYN 369
Query: 603 VTKEERHIVKPLYDRYRLVKQMLTRASIT---PVLGSPSTKRRGQMLQPIIEGETAHFFE 659
++ R + R R S T SPS + R + E E H E
Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK-DKKREKERDHISE 428
Query: 660 EIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
+ E + SS D + + +SL+ E + E
Sbjct: 429 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 466
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 47.8 bits (112), Expect = 4e-05
Identities = 59/335 (17%), Positives = 145/335 (43%), Gaps = 75/335 (22%)
Query: 464 KDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQ 523
++EK ++R + +++ ++KIR+ EE+ R+ + + + W E ++
Sbjct: 293 QEEKIQERE--EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-----EK 345
Query: 524 IKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL 583
I++ + K + E + + ++E+ ++E K+ ++EK+ +EA +
Sbjct: 346 IRELEEKMHEQEKIRE------------------QEEKRQEEEKIREQEKRQEQEAKMWR 387
Query: 584 ILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRG 643
++++E+ + E++ +EE+ G
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEK---------------------------------MG 414
Query: 644 QMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKL 703
+ + + E E EE++E+EE ++ + K + + + E ++E +EK+
Sbjct: 415 EQEEKMWEQE-----EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 704 ALDLRLSSSRAASMPELLEQL----WKARAEKKKLR---KTLREFEEAFYQQNGRNAQKE 756
+ A M E E++ K R ++KK+R + +RE EE +Q + ++E
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529
Query: 757 DRV-----PVLEEYREYKKIKAKLRLLEVLISKQD 786
+++ + E+ + ++ + K+R EV + +Q+
Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQE 564
Score = 33.1 bits (74), Expect = 1.0
Identities = 45/236 (19%), Positives = 102/236 (43%), Gaps = 44/236 (18%)
Query: 559 DEENEDEPKVIQKEKK--PSKEATLELILKRLKEK--RIERCLPEDIKVTKEERHIVKPL 614
DEE +++ +Q++ + S+++ ++L +K LK K R + LP+ ++ E H+ K L
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKEL 262
Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674
S S K + Q+ E + + +++E+ + E
Sbjct: 263 Q--------------------SVSAKLQAQV-------EENELWNRLNQQQEEKMWRQEE 295
Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
+ + ++ E + E +EK+ + + M E +W+ + ++L
Sbjct: 296 ------KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 349
Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYK----KIKAKLRLLEVLISKQD 786
+ + E E+ Q+ R Q+E+++ E+ +E + + + K+R E I +Q+
Sbjct: 350 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403
Score = 30.4 bits (67), Expect = 6.7
Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 71 EDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEE----EDEKL 126
E ++EQE R + E + +EE + + EQ ++ E+EE ++EK+
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE-GKMCEQEAKMQEQEEKMRRQEEKI 497
Query: 127 EHIEELPEEGAEKSNDMPEVVQ 148
E+ E EK + E++Q
Sbjct: 498 REQEKKIREQEEKIREQEEMMQ 519
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 47.4 bits (111), Expect = 5e-05
Identities = 64/345 (18%), Positives = 146/345 (42%), Gaps = 33/345 (9%)
Query: 434 SQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFER 493
++R+ D + +S ++R +F+ D++ + VKK +++ ++ +
Sbjct: 81 TKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQE 140
Query: 494 ERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGS 553
+ N K +Y+ RK++ K GE Q RP ++ L ++
Sbjct: 141 KMNEK-NYT-----------------FRKRVVIKKPWLRLGEVTAQKRPENSLLEETL-- 180
Query: 554 SLDHEDEENEDEPKVIQKEKKPSKEATLELIL-KRLKEKRIERCLPEDIKVTKEERHIVK 612
DH K+ ++ PS E I + LKEK E L E +++ + E+ ++
Sbjct: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAE--LQEKLRLVESEKSEIQ 238
Query: 613 PLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLS 672
+ +K+ L RA + +L + L ++ +A +++E E +
Sbjct: 239 L---NVKDLKRKLERAQL--LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293
Query: 673 SELGDMLKTAVQVQSSLEN---SESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARA 729
+ M + ++Q E E + E +EK+ + + E +++W+
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353
Query: 730 EKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEE--YREYKKIK 772
+ ++ + +RE EE ++Q + ++++++ EE +R+ +KI+
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR 398
Score = 39.3 bits (90), Expect = 0.014
Identities = 45/232 (19%), Positives = 110/232 (47%), Gaps = 24/232 (10%)
Query: 557 HEDEEN--EDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPL 614
HE EE E E K+ ++E+K ++ ++++E+ E+ ++ K+ +++ I +
Sbjct: 335 HEQEEKIREQEDKMWRQEEKIREQE------EKIREQE-EKMWRQEEKIREQDEKIQEQE 387
Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674
+ +R +++ + KR+ +M + E + E+I+E+EE+ +
Sbjct: 388 EEMWRQEEKIREQEE----------KRQEKMWRQ--EKKMREQDEKIREQEEEMWRQEEK 435
Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
+ ++ + + L E ++E +EK+ + + E E+ W+ K+
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495
Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQD 786
K + E EE ++Q + ++E+++ EE + ++ + K+R EV + +Q+
Sbjct: 496 EK-IWEQEEKMWRQEEKMWEQEEKMQEQEE--KMQRQEEKMREQEVRLWQQE 544
Score = 35.0 bits (79), Expect = 0.27
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 71 EDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEE-EEEDEKLEHI 129
++ K QE + R + E + E EEE + E++ EL E ++++EKL +
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE------EKIRELEEMMQDQEEKLREV 453
Query: 130 EELPEEGAEKSNDMPEVVQLRMTENILESNSVT 162
EE +E EK + E +Q R E I E T
Sbjct: 454 EEKMQEEEEKMQEQEEKIQ-RQEEKIQEQEEKT 485
Score = 34.7 bits (78), Expect = 0.35
Identities = 51/299 (17%), Positives = 128/299 (42%), Gaps = 25/299 (8%)
Query: 469 EDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQ---IK 525
E+ + L+ + Q++ +E+ +E+ K ++ + K + K+ +Q I+
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342
Query: 526 DAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELIL 585
+ + K E + R + + + E++ E + K+ ++E++ ++ E +
Sbjct: 343 EQEDKMWRQE--EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ---EEKI 397
Query: 586 KRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQM 645
+ +EKR E+ ++ K+ +++ I + + +R +++ + +M
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI---------------RELEEM 442
Query: 646 LQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLAL 705
+Q + E EE +EEE+ + E + +Q Q + + + +EK+
Sbjct: 443 MQD--QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500
Query: 706 DLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEE 764
+ M E E++ + + ++ + +RE E +QQ + ++E R+ LEE
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559
>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
Length = 1780
Score = 46.2 bits (108), Expect = 1e-04
Identities = 60/332 (18%), Positives = 146/332 (43%), Gaps = 31/332 (9%)
Query: 476 LVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKH------ 529
++ KL++ +++F+E + +S + D+ N K LK E+T+L ++D KH
Sbjct: 1153 IILKLERNLKEFQEHLQ---DSVKNTKDL--NVKELKLKEEITQLTNNLQDMKHLLQLKE 1207
Query: 530 -----KNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELI 584
+ E + + S+ ++ + L ++E+ D + + KK K+ E+
Sbjct: 1208 EEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVS 1267
Query: 585 LKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRG- 643
+ R ++K + + E + K++ + L + R ++Q+ + + V + R
Sbjct: 1268 VMRDEDKLLRIKINE---LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERAC 1324
Query: 644 ---QMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQ 700
+ + IIE E+ + + E L ++L ++ + A +++ E +N
Sbjct: 1325 KDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNN 1384
Query: 701 EKLALDLRLSSSRAASMPELLEQL----WKARAEKKK-LRKTLREFEEAFYQQNGRNAQK 755
++ + ++ + L ++L K A++KK L + + +A +N RN +
Sbjct: 1385 QRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEM 1444
Query: 756 EDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787
+ E+ + K + ++ +L ++++DS
Sbjct: 1445 K---KYAEDRERFFKQQNEMEILTAQLTEKDS 1473
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 45.8 bits (107), Expect = 2e-04
Identities = 56/312 (17%), Positives = 138/312 (44%), Gaps = 17/312 (5%)
Query: 475 QLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDG 534
+L ++ +++ ++ +E ER++ P+ +D + + + + + K+ K ++
Sbjct: 99 RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 158
Query: 535 EFVPQTRPRSNTLPKSFGSS--LDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKR 592
+ + + T+ KS+ + D E+ + ED+ K ++E+KP + + E ++ + E++
Sbjct: 159 RYEIE---ETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEK 215
Query: 593 IERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEG 652
E + ++ + I + +Q S + K R + + +E
Sbjct: 216 TTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKM-EEEDKERAEAERARLEA 274
Query: 653 ETAHFFEEIKEEEEDGV-NLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALD----L 707
E E IK E++ + + + + K A Q + E E + +EK A + +
Sbjct: 275 EER---ERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331
Query: 708 RLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYRE 767
+ RAA + +++ K AE+ R+ ++E E+ ++ R +E+ +EE +
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEE---RQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR 388
Query: 768 YKKIKAKLRLLE 779
K+++ K ++
Sbjct: 389 NKQLEEKKHAMQ 400
Score = 39.3 bits (90), Expect = 0.014
Identities = 78/432 (18%), Positives = 166/432 (38%), Gaps = 54/432 (12%)
Query: 391 KSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKA 450
K +ED E EA+ + E + R+ + + + E+ ++ +
Sbjct: 256 KMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERE 315
Query: 451 LSFTRIRRSSFSS---KDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAAN 507
+R++ K+E++ Q +K+ +K+ + ++ + E A
Sbjct: 316 RMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA 375
Query: 508 PKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED--E 565
+ K E K KQ+++ KH + +T+ + + + +E + ED +
Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHA------MQETKIKGEKVEQKIEGKWVNEKKAQEDKLQ 429
Query: 566 PKVIQK---EKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVK 622
V++K EK +A E + + + E E IK KE + VK DR
Sbjct: 430 TAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDR----- 484
Query: 623 QMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFE------EIKEEEEDGVNLSSELG 676
+ T V + G+ + ++ T + F + +E +G E G
Sbjct: 485 ----KKGFTEV-----KSQNGEFMTHKLK-HTENTFSRPGGRASVDTKEAEGAP-QVEAG 533
Query: 677 DMLKTAVQVQSSLENSESD-VEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLR 735
L+ + + E+ E + +++ Q++ AL+L + ++LE+ + R +++ R
Sbjct: 534 KRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADR 593
Query: 736 KTLREFE-----EAFYQQNGRNAQKEDRVP---VLEEYREYK---------KIKAKLRLL 778
K E E E ++ A+K ++P + ++ + +K KI+ + L
Sbjct: 594 KLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFL 653
Query: 779 EVLISKQDSSKS 790
+ K KS
Sbjct: 654 NKSVQKSSGVKS 665
Score = 30.4 bits (67), Expect = 6.7
Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 14/98 (14%)
Query: 74 KEQEIVSRIMAGLLENYYEFFENEE--EDFSSNDLSSITEQVNELSEEEEEDEKLEHIEE 131
KE++ SR + YE E E + + ND E E E+EEE+ EE
Sbjct: 149 KEEKSESR------QERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE------EE 196
Query: 132 LPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHIS 169
P+ G+ N + +V+ + TE+ E+ ++ + IS
Sbjct: 197 KPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQIS 234
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 45.4 bits (106), Expect = 2e-04
Identities = 62/269 (23%), Positives = 109/269 (40%), Gaps = 38/269 (14%)
Query: 479 KLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKH--KNSDGEF 536
+L KKI + + Q ERE+ S ++ EL + ++Q++ K
Sbjct: 505 QLSKKIEKLQTQLEREKQSNQDLETLS---------EELIREKEQLQSDMETLKADKARQ 555
Query: 537 VPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERC 596
+ + L ++ S + +E K ++KE K + E K + + +R
Sbjct: 556 IKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQ 615
Query: 597 LPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 656
L D++ KE+ +R +++ L R + G++ + + ETA
Sbjct: 616 LHRDLEQAKEKG-------ERAEKLERELQRLQ----------EENGRLARKVTSLETAT 658
Query: 657 FFEEIKEEEEDGVNLSSE-LGDMLKTAVQVQSSLENSESDVE----ENQE--KLALDLRL 709
E E E G+ L + L L T V LE E D + EN E +L +R
Sbjct: 659 EKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRF 718
Query: 710 SSSRAASMPELLEQLWKARAEKKKLRKTL 738
+S++ A M +QL EK++LRK +
Sbjct: 719 TSTKLAQMERENQQL---EREKEELRKNV 744
>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
Length = 698
Score = 45.1 bits (105), Expect = 3e-04
Identities = 32/122 (26%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 9 NEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASH-HEEIWSANSLAAVFGPDVF--H 65
+E E +L + LP NY+LL+++C+FL V ++ + S +LA VFGP++
Sbjct: 261 DEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQ 320
Query: 66 IYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEK 125
+ V M+ +V +M L+ + + F + ++ + V SEE D +
Sbjct: 321 VEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQ 380
Query: 126 LE 127
E
Sbjct: 381 GE 382
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 44.3 bits (103), Expect = 4e-04
Identities = 61/335 (18%), Positives = 150/335 (44%), Gaps = 34/335 (10%)
Query: 455 RIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQ-FERERNSKPSYSDIAANPKVLKW 513
+IR ++++ + R +++ + ++K+R+ EE +E+E + + + ++
Sbjct: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRE 381
Query: 514 MTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEK 573
+ E +++I++ + K + E + + R K + E++ E E K+ ++EK
Sbjct: 382 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ----EEKIREQEEKIREQEK 437
Query: 574 KPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPV 633
K ++ E I ++ K + E+ ++ +EE+ ++ + +R ++M + I
Sbjct: 438 KMWRQE--EKIHEQEKIREEEKRQEQEEMWRQEEK--IREQEEIWRQKEKMHEQEKI--- 490
Query: 634 LGSPSTKRRGQMLQPIIEGETAHFFEE-IKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692
R Q + + E H EE I+E+EE ++ + + + + +
Sbjct: 491 --------RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542
Query: 693 ESDVEENQEKLALD---LRLSSSRAASMPELLEQLWKARAEKKKLRKT----------LR 739
E ++E +EK+ ++ ++ EQ K R +K+K+R+ +R
Sbjct: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIR 602
Query: 740 EFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAK 774
E EE +Q + ++E+++ EE + ++ K +
Sbjct: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637
Score = 41.6 bits (96), Expect = 0.003
Identities = 48/236 (20%), Positives = 110/236 (46%), Gaps = 23/236 (9%)
Query: 559 DEENEDEPKVIQKEKK--PSKEATLELILKRLKEK--RIERCLPEDIKVTKEERHIVKPL 614
DEE +++ +Q++ + S+++ ++L +K LK K R + LP+ ++ E H+ K L
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKEL 274
Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674
++ + + L ++ + + I E E E+I+E+EE +
Sbjct: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE-----EKIQEQEE-------K 322
Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
+ + + + + + E + E +EK+ + + M L E +W+ + ++L
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382
Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYK----KIKAKLRLLEVLISKQD 786
+ + E E+ Q+ R Q+E+++ E+ +E + + + K+R E I +Q+
Sbjct: 383 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 44.3 bits (103), Expect = 4e-04
Identities = 79/393 (20%), Positives = 153/393 (38%), Gaps = 88/393 (22%)
Query: 466 EKREDRTPYQLV--KKLQKKIRQFEEQFERERNS--KPSYSDIAANPKVLKWMTE----- 516
E+ E+R + KK+Q+ I++ EEQ E E ++ K + K+ K E
Sbjct: 925 EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984
Query: 517 -----LTKLRKQIKD-------------------AKHKNSDGEFVPQTRPR--------- 543
L K +K ++D AK KN + R
Sbjct: 985 DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044
Query: 544 --SNTLPKSFGSSLDHEDEENEDEPKVIQ-KEKKPSKEATLELILKRLKEKRIERC---- 596
T K G S D D+ E + ++ + K + KE L+ L R++E+ ++
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104
Query: 597 -----------LPEDI--------KVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSP 637
L ED+ K K++R + + L ++ L + L S
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS- 1163
Query: 638 STKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
++ +L+ +E E +I+E + EL + L+ +V+++LE ++ +E
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223
Query: 698 ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKED 757
+ +LA ++++ LL+ + ++KK+ L+E + F + + D
Sbjct: 1224 NERGELANEVKV----------LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELAD 1273
Query: 758 RVPVLEEYREYKKIKAKLRLLEVLISKQDSSKS 790
+V K++ +L + L+S+ DS S
Sbjct: 1274 KV---------TKLQVELDNVTGLLSQSDSKSS 1297
Score = 37.7 bits (86), Expect = 0.042
Identities = 70/375 (18%), Positives = 147/375 (39%), Gaps = 51/375 (13%)
Query: 433 QSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFE 492
Q +R L ++ K ++R +DE+++ KKL+ ++ E +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627
Query: 493 RERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSD-----GEFVPQTRPRSNTL 547
+AN + + +L KL+ Q+KD + D E + Q + L
Sbjct: 1628 ------------SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKL 1675
Query: 548 PKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL-----------ILKRLKEKRIERC 596
S++ E + ++E ++ K+ +++ EL L +++R+E
Sbjct: 1676 -----KSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEAR 1730
Query: 597 LPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 656
+ + + +EE+ + + DR + + + + T + S ++ + + +E +
Sbjct: 1731 IAQLEEELEEEQGNTELINDRLKKANLQIDQIN-TDLNLERSHAQKNENARQQLERQNKE 1789
Query: 657 FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQ---------EKLALDL 707
++K +E +G S + ++ E +++ +E Q EK D+
Sbjct: 1790 L--KVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV 1847
Query: 708 RLS-SSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNG--RNAQK--EDRVPVL 762
L + + +Q KA K+L++ L E EE + N R Q+ ED
Sbjct: 1848 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1907
Query: 763 EEY-REYKKIKAKLR 776
+ RE +K KLR
Sbjct: 1908 DAMNREVSSLKNKLR 1922
Score = 36.2 bits (82), Expect = 0.12
Identities = 52/293 (17%), Positives = 113/293 (38%), Gaps = 29/293 (9%)
Query: 464 KDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQ 523
++E R+ + +K+++ + F EQ E E +K + ++ L Q
Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK------------QIATLHAQ 1365
Query: 524 IKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL 583
+ D K K D +T + + + L+ + +E++ K +K EL
Sbjct: 1366 VADMKKKMEDSVGCLET---AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQEL 1422
Query: 584 --ILKRLKEKRIERCLPEDIKVTKE----ERHIVKPLYDRYRLVKQMLTRASITPVLGSP 637
+L L +R C E + + E + Y R + R T L
Sbjct: 1423 DDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLA 1482
Query: 638 STKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
+ +E F E+++ ++ + ++ K+ ++ +E ++ +E
Sbjct: 1483 RALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 1542
Query: 698 ENQE--------KLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFE 742
E ++ KL L++ L + +A +L + ++ +KK+L + +RE E
Sbjct: 1543 ELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME 1595
Score = 35.4 bits (80), Expect = 0.21
Identities = 63/338 (18%), Positives = 146/338 (43%), Gaps = 56/338 (16%)
Query: 478 KKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFV 537
KK++ ++++ + +F + +D KV K EL + +
Sbjct: 1248 KKVEAQLQELQVKFNEGERVRTELAD-----KVTKLQVELDNVTGLLS------------ 1290
Query: 538 PQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCL 597
Q+ +S+ L K F + + + +D +++Q+E + ++ +L LK++++++
Sbjct: 1291 -QSDSKSSKLTKDFSAL----ESQLQDTQELLQEENR--QKLSLSTKLKQVEDEK--NSF 1341
Query: 598 PEDIKVTKEERH-IVKPLYDRYRLVKQMLTRA--SITPVLGSPSTKRRGQMLQPIIEGET 654
E ++ +E +H + K + + V M + S+ + + KR+ LQ +EG +
Sbjct: 1342 REQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRK---LQKDLEGLS 1398
Query: 655 AHFFEEIK---EEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE-------------- 697
E++ + E+ L EL D+L + S N E +
Sbjct: 1399 QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISA 1458
Query: 698 ---ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLR-EFEEAFYQQN--GR 751
E +++ + R ++A S+ LE+ + +AE ++L K R E E+ ++ G+
Sbjct: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK 1518
Query: 752 NAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSK 789
+ + ++ E ++ +++K +L LE + + +K
Sbjct: 1519 SVHELEKSKRALE-QQVEEMKTQLEELEDELQATEDAK 1555
Score = 33.1 bits (74), Expect = 1.0
Identities = 50/211 (23%), Positives = 87/211 (41%), Gaps = 26/211 (12%)
Query: 95 ENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEH-----IEELPEEGAEKSNDMPEVVQ- 148
EN ++ S L + ++ N E+ EE+E+ +H I L + A+ M + V
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379
Query: 149 LRMTENI---LESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDLQSSIDHDLK 205
L E + L+ + + H + A+ D LE+T + ++Q L DL +DH
Sbjct: 1380 LETAEEVKRKLQKDLEGLSQRHEEKV----AAYDKLEKT-KTRLQQELDDLLVDLDH--- 1431
Query: 206 NLQQQSVVCNNEAESIHCD---GEGSNNQIDIADDIINA-SESNRDCSKPVASTNLDNEA 261
Q+ CN E + D E A++ A +E+ +K ++ EA
Sbjct: 1432 ---QRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA 1488
Query: 262 MQQDCVFE--NEENTQSVGILLEPCSDRGDS 290
M+Q E N++ + L+ D G S
Sbjct: 1489 MEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 44.3 bits (103), Expect = 4e-04
Identities = 76/361 (21%), Positives = 147/361 (40%), Gaps = 59/361 (16%)
Query: 439 HDPEKLDSSSKALSFTRIRRSSFSSK--DEKREDRTPYQLVKKLQKKIRQFEEQFERERN 496
+D ++LD K F S SK DE+ + +K+LQ +I + EE+ E ER
Sbjct: 1075 NDKQQLDEKLKKKEF---EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERA 1131
Query: 497 SKPSYSDIAANPKVLKWMTELTKLRKQIKDA---------KHKNSDGEFVPQTR------ 541
S+ A + EL ++ +++++A +K + EF R
Sbjct: 1132 SRAK-----AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEAT 1186
Query: 542 ----PRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL--------ILKRLK 589
+ TL K S+ E+ ++ +V QK +K E +E+ + + K
Sbjct: 1187 LQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAK 1246
Query: 590 E--KRIERCLPEDIK--VTKEERHIVKPLYDRYRLVKQMLT-RASITPVLGSPSTK--RR 642
+++ R L + + TKEE ++ RL+ + RA + G S + +
Sbjct: 1247 GNLEKMCRALEDQLSEIKTKEE--------EQQRLINDLTAQRARLQTESGEYSRQLDEK 1298
Query: 643 GQMLQPIIEGETA--HFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQ 700
++ + G+ A EE+K + E+ + S L L+++ L + +E +
Sbjct: 1299 DTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAK 1358
Query: 701 EKLALDLRLSSSRAASM-----PELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQK 755
+L + ++S A + +++ + KKKL + L++ EE N + A
Sbjct: 1359 AELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASL 1418
Query: 756 E 756
E
Sbjct: 1419 E 1419
Score = 35.8 bits (81), Expect = 0.16
Identities = 68/329 (20%), Positives = 144/329 (43%), Gaps = 46/329 (13%)
Query: 475 QLVK---KLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKN 531
QL+K +L+ KI++ E+ E E +++ A + L+ E ++L+K I D +
Sbjct: 911 QLIKTKIQLEAKIKEVTERAEDEEEIN---AELTAKKRKLE--DECSELKKDIDDLELTL 965
Query: 532 SDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILK-RLKE 590
+ E + ++ +L E ++ + KEKK +EA + + + +E
Sbjct: 966 AKVE-------KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018
Query: 591 KRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPII 650
++ IK+ ++ + L ++ + ++ L RA + G + M I
Sbjct: 1019 DKVNTLTKAKIKLEQQVDDLEGSL-EQEKKIRMDLERAK-RKLEGDLKLAQESTM---DI 1073
Query: 651 EGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLS 710
E + E++K++E + L S++ D +Q+Q ++ ++ +EE +E++ + R S
Sbjct: 1074 ENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAE-RAS 1132
Query: 711 SSRA--------ASMPELLEQLWKA-----------RAEKKKLRKTLREFEEAFYQQNGR 751
++A + E+ E+L +A + + + +K R+ EEA Q
Sbjct: 1133 RAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEAT 1192
Query: 752 NA----QKEDRVPVL-EEYREYKKIKAKL 775
A + D V L E+ +++K KL
Sbjct: 1193 AATLRKKHADSVAELGEQIDNLQRVKQKL 1221
Score = 31.6 bits (70), Expect = 3.0
Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 10/125 (8%)
Query: 653 ETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSS 712
+ A EE+K+E++ +L ++ +T +Q L+ +E + +K ++ +
Sbjct: 1765 DAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKK---QIQKLEA 1821
Query: 713 RAASMPELLEQLWKARAEK-KKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKI 771
R + +E K E K LRK R+ +E YQ +EDR +L K+
Sbjct: 1822 RVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQ------TEEDRKNILRLQDLVDKL 1875
Query: 772 KAKLR 776
+AK++
Sbjct: 1876 QAKVK 1880
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 43.9 bits (102), Expect = 6e-04
Identities = 59/278 (21%), Positives = 113/278 (40%), Gaps = 24/278 (8%)
Query: 516 ELTKLRKQIKDAKHK-NSDGEFVPQTRPRSNTLPKSFGSSLDHEDEEN-EDEPKVIQKEK 573
E+ KL KQ+ D + N + V + + + + S+ D++N + E +Q E
Sbjct: 424 EIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLAST--RRDQDNMQAELNRLQAEN 481
Query: 574 KPSKEATLELILKRLKEKRI--ERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASIT 631
SKE E +L+ L+E + ++ E TKE + L + + +
Sbjct: 482 DASKEEVKE-VLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL 540
Query: 632 PVLGSPSTKRRGQM----LQPIIEGETAHFFEEIKEEEEDGV-------------NLSSE 674
+ + KR +M L+ + E A ++K+ E G+ + SE
Sbjct: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600
Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
+ M+K Q++S+ S +EEN+++LA S A + L E L +K++L
Sbjct: 601 VKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQL 660
Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIK 772
+++ E Q + E L + + ++K
Sbjct: 661 EESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVK 698
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 43.9 bits (102), Expect = 6e-04
Identities = 61/249 (24%), Positives = 106/249 (42%), Gaps = 45/249 (18%)
Query: 537 VPQTRPRSNTLP----KSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKR 592
+PQ R LP + +G + +EE E+E + +K KKP E ++E
Sbjct: 1473 MPQYGSRRRLLPPAGQEEYGEVVGEAEEEYEEEEEEPKKIKKPKVE---------IREPS 1523
Query: 593 IERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQM-LQPIIE 651
E E++ VT E+ +P Y ++ RA I P++ K RG + I++
Sbjct: 1524 EE----EEVVVTIEKPPAAEPTYTTWK-------RARIFPMI---FKKVRGLADKRGIVD 1569
Query: 652 GETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQ---------VQSSLENSESDVEENQEK 702
E + ++EE++D + L+ + + ++ V+ + S E SE E E+
Sbjct: 1570 LEGEEWQRRLEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEE 1629
Query: 703 LALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTL-----REFEEAFYQQNGR--NAQK 755
+ S +S PE E+ +E +K RK + R E + GR Q+
Sbjct: 1630 ESESETPSEEEESSTPE-SEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQE 1688
Query: 756 EDRVPVLEE 764
E + P +EE
Sbjct: 1689 EQKEPKMEE 1697
Score = 32.3 bits (72), Expect = 1.8
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 97 EEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTEN 154
E E+ SS+D + +E+ +E SE E +E+ E E P E E S PE + TE+
Sbjct: 1602 ESEEESSSDYTEYSEEESEFSESETTEEESE--SETPSEEEESST--PESEESESTES 1655
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 43.9 bits (102), Expect = 6e-04
Identities = 141/742 (19%), Positives = 284/742 (38%), Gaps = 92/742 (12%)
Query: 62 DVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEE 121
DV + +E+ +Q V+ I + E + NEE+ ++ ++ EQ+N LS EE
Sbjct: 888 DVETLQQTIEEKDQQ--VTEISFSMTEKMVQL--NEEKFSLGVEIKTLKEQLNLLSRAEE 943
Query: 122 -EDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
+ E++E E+ + ++M Q+ E E +L +
Sbjct: 944 AKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHE-------------FDLLKKENEQ 990
Query: 181 LERTIRAAV--EQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIAD-- 236
+R ++AA+ + L S ++ +L NL+ +S +I +++
Sbjct: 991 RKRKLQAALINRKELLQRVSRLEEELANLKDES-----------------KKEIPLSETE 1033
Query: 237 --DIINASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGC 294
++ E+ K V S + E + + E E Q + LE +
Sbjct: 1034 RGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL 1093
Query: 295 LEREEYLLFDSDKLSHLI---LDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLD 351
+++ L D L+ + + I + ++ G SV + E +S P
Sbjct: 1094 VKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPC-- 1151
Query: 352 LKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRM 411
+ W+ P ++ K + L+++ E+ K QE S +A L +A
Sbjct: 1152 ---TGSSEHWK-------PELEEKILALEKEKEQ---LQKKLQEALTSRKAILK-KAQEK 1197
Query: 412 NHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEK----LDSSSKALSFTRIRRS---SFSSK 464
H EE L + D+ + Q + K + + L ++R S S
Sbjct: 1198 ERHLREE-----LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQI-QVRESIDGKLPST 1251
Query: 465 DEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQI 524
D++ + L + L K Q Q E N P + + + L+ T + +++ Q+
Sbjct: 1252 DQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQL 1311
Query: 525 KDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATL--E 582
K+ + + + E + ++ L K +++ N+ + I+ K S EA + E
Sbjct: 1312 KEIEAEKVELEL--KVSSTTSELTKKSEEVFQLQEQINKQGLE-IESLKTVSHEAEVHAE 1368
Query: 583 LILKRLKEKRIERCLPEDI-----KVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSP 637
+ ++L+ +++ E + K+ + ++ I K D L Q+ + + + +
Sbjct: 1369 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE 1428
Query: 638 STKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
++ + +I+ + KE +E L EL +M + ++ E S + +
Sbjct: 1429 IIEQ-----EDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIG---EESRAK-Q 1479
Query: 698 ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKED 757
+ Q KL L L E+L AR ++L K+L + E QN
Sbjct: 1480 QIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLG 1539
Query: 758 RVPVLEEYREYKKIKAKLRLLE 779
R+ +L+E R+ + LLE
Sbjct: 1540 RLALLQEERDKLITEMDRSLLE 1561
Score = 43.5 bits (101), Expect = 8e-04
Identities = 136/752 (18%), Positives = 287/752 (38%), Gaps = 121/752 (16%)
Query: 71 EDMKEQEIVSRIMAGLLENYYEFFENE--EEDFS---------SNDLSSITEQVNELSEE 119
E +Q+I ++ A L+ EN+ +E+ S + L+ + QV+ ++
Sbjct: 1474 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS--AQN 1531
Query: 120 EEEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTD 179
+E+D L + L EE + +M ++LE+ S++++ + L T+
Sbjct: 1532 KEKDTVLGRLALLQEERDKLITEMDR--------SLLENQSLSSSCESLK--LALEGLTE 1581
Query: 180 ILERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVV---------CNNEAESIHCDGEGSNN 230
E+ ++ + S + K+ + Q +NEAE I E
Sbjct: 1582 DKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQ 1641
Query: 231 QIDIADDIINASESNR-DCSKPVASTNLDNEAMQ----------QDCVFENEENTQSVGI 279
+ + ++E+N+ + K + + E M+ Q + E EE +
Sbjct: 1642 EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRA 1701
Query: 280 LLEPCSDRGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLN-ANTESEVPGGQSVGV 338
+ P GD+ C+E L+ ++S +L E E + +
Sbjct: 1702 EVHPA---GDTAKECMET-------------LLSSNASMKEELERVKMEYETLSKKFQSL 1745
Query: 339 QGEAACVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSE 398
E +S DLK+ +G+ + + D +T ++ +G + P E E
Sbjct: 1746 MSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQT-NVTEEGTQSIPG-----ETEE 1799
Query: 399 SGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRR 458
+S + P + P +S + +L ++L L + +
Sbjct: 1800 QDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKN 1859
Query: 459 SSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELT 518
FS E ++ Q+ K +++ +E+ + N ++ + ++ +T
Sbjct: 1860 KEFSQTLENEKNTLLSQISTK-DGELKMLQEEVTKMN---------LLNQQIQEELSRVT 1909
Query: 519 KLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPK--VIQKEKKPS 576
KL++ ++ K + N L + GS ++ + + + K +++ E K
Sbjct: 1910 KLKETAEEEKDDLEERLM--------NQLAELNGSIGNYCQDVTDAQIKNELLESEMKNL 1961
Query: 577 KEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGS 636
K+ EL E+ ++ + E KV E R K+ L + I
Sbjct: 1962 KKCVSEL------EEEKQQLVKEKTKVESEIR-------------KEYLEK--IQGAQKE 2000
Query: 637 PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDV 696
P K + LQ +++ + +E+K+ ++D + ++ + +T ++ S+ D+
Sbjct: 2001 PGNKSHAKELQELLKEKQ----QEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL 2056
Query: 697 EENQEKLALDL---RLSSSRAASMPELLE----QLWKARAEKKKLRKTLREFEEAFYQQN 749
E +E LA + + + + AS LL+ + + A+ KL+K L+ +E+ Q
Sbjct: 2057 EITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQ- 2115
Query: 750 GRNAQKEDRVPVLEEYREYKKIKAKLRLLEVL 781
QK++ + E E K +K K + E L
Sbjct: 2116 --MKQKDEDLERRLEQAEEKHLKEKKNMQEKL 2145
Score = 40.4 bits (93), Expect = 0.006
Identities = 63/325 (19%), Positives = 127/325 (39%), Gaps = 53/325 (16%)
Query: 469 EDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAK 528
E R Q+ +KLQ + +E + ++ + S + +L K + D +
Sbjct: 1474 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGT---------IERLTKSLADVE 1524
Query: 529 HKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRL 588
+ S Q + + L + + + E + +++ + S +L+L L+ L
Sbjct: 1525 SQVS-----AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGL 1579
Query: 589 KE------KRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRR 642
E K IE I + E + K L Y ++ Q S
Sbjct: 1580 TEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVS-----------NE 1628
Query: 643 GQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEK 702
+ +Q H E +++E+++ L +L + + L+ +E ++EE +EK
Sbjct: 1629 AERIQ--------HVVEAVRQEKQE---LYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677
Query: 703 LALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVL 762
+ + + S+ + EL E+ + RAE T +E E N ++ +RV +
Sbjct: 1678 MR---KFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM- 1733
Query: 763 EEYREYKKIKAKLRLLEVLISKQDS 787
EY+ + K + L+S++DS
Sbjct: 1734 ----EYETLSKK---FQSLMSEKDS 1751
Score = 37.0 bits (84), Expect = 0.071
Identities = 79/368 (21%), Positives = 152/368 (41%), Gaps = 31/368 (8%)
Query: 410 RMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDE--- 466
++N LE + +SH + +S + +KL+SS ++ R DE
Sbjct: 1345 QINKQGLEIESLKTVSHEAEVHAESLQ-----QKLESSQLQIAGLEHLRELQPKLDELQK 1399
Query: 467 ---KREDRTPY---QLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKL 520
K+E+ Y QL +K + E E+E K ++ + K + + +L
Sbjct: 1400 LISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK--EHDERIKQL 1457
Query: 521 RKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEAT 580
+ ++ + K K E ++R + K + + ++ E+ K +Q+E ++ T
Sbjct: 1458 QVELCEMKQKPE--EIGEESRAKQQIQRKLQAALISRKEALKEN--KSLQEELSLAR-GT 1512
Query: 581 LELILKRLKEKRIERCLPEDIKVT--------KEERHIVKPLYDRYRLVKQMLTRASITP 632
+E + K L + + K T +EER + DR L Q L+ + +
Sbjct: 1513 IERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESL 1572
Query: 633 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692
L + L IE + E E +E L E +L++ V + E
Sbjct: 1573 KLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERI 1632
Query: 693 ESDVEE-NQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGR 751
+ VE QEK L +L S+ A + E +QL +A E +++++ +R+F ++ Q+
Sbjct: 1633 QHVVEAVRQEKQELYGKLRSTEA-NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILE 1691
Query: 752 NAQKEDRV 759
++ DR+
Sbjct: 1692 LEEENDRL 1699
Score = 35.8 bits (81), Expect = 0.16
Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 16/146 (10%)
Query: 72 DMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEE 131
+MKEQ+I+S LL E + + I E N LS+EEEE+ LE E
Sbjct: 2378 NMKEQKIIS-----LLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLE---E 2429
Query: 132 LPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQ 191
++ +K+N + E ++ ENI + + + + +S L D + + E+
Sbjct: 2430 ENKKAVDKTNQLMETLKTIKKENIQQKAQL---DSFVKSMSSLQNDRDRIVGDYQQLEER 2486
Query: 192 HLFDLQSSIDHDLKNLQQQSVVCNNE 217
HL SI + L Q++ NN+
Sbjct: 2487 HL-----SIILEKDQLIQEAAAENNK 2507
Score = 33.1 bits (74), Expect = 1.0
Identities = 41/142 (28%), Positives = 71/142 (50%), Gaps = 19/142 (13%)
Query: 650 IEGETAHFFEEIKEEEEDGVNLS-SELGDMLKTAVQVQSSLENSESDVEENQEKLALDLR 708
IE ++ E+ + E D V L SE ++++ +QS L+N ES+V E E++
Sbjct: 803 IEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRS---LQSQLQNKESEVLEGAERVR---H 856
Query: 709 LSS-----SRAASMPEL-LEQLWKARAEKKKLRKTLRE-FEEAFYQQNGRNAQKEDRVPV 761
+SS S+A S EL + ++ + EKK+ +TL++ EE Q + +++
Sbjct: 857 ISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQ 916
Query: 762 LEEYR-----EYKKIKAKLRLL 778
L E + E K +K +L LL
Sbjct: 917 LNEEKFSLGVEIKTLKEQLNLL 938
Score = 31.6 bits (70), Expect = 3.0
Identities = 39/164 (23%), Positives = 66/164 (40%), Gaps = 25/164 (15%)
Query: 69 DVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEH 128
++ +KEQ +++R LL F N E+ S + L + +Q+ +DE+L H
Sbjct: 2767 ELAQLKEQGLLNRERDALLSET-AFSMNSTEENSLSHLEKLNQQLLS------KDEQLLH 2819
Query: 129 IEELPEEGAEKSNDMPEVVQLRMTE-----NILES--NSVTATSTHISPISILPASTDIL 181
+ E+ + + + E N LE S + S PA L
Sbjct: 2820 LSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSL 2879
Query: 182 ERTIRAAVEQHLFDLQSSIDH---DLKNLQQQSVVCNNEAESIH 222
++ + + LQ+ D +LKNLQQQ + N E +H
Sbjct: 2880 KKAMSS--------LQNDRDRLLKELKNLQQQYLQINQEITELH 2915
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,529,093
Number of Sequences: 37866
Number of extensions: 1492826
Number of successful extensions: 11130
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 551
Number of HSP's that attempted gapping in prelim test: 8259
Number of HSP's gapped (non-prelim): 2614
length of query: 791
length of database: 18,247,518
effective HSP length: 110
effective length of query: 681
effective length of database: 14,082,258
effective search space: 9590017698
effective search space used: 9590017698
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.