Guide to the Human Genome
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Search of human proteins with 156142192

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo
sapiens]
         (791 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]  1565   0.0  
gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]  1506   0.0  
gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]  1491   0.0  
gi|56119110 family with sequence similarity 13, member A1 isofor...   484   e-136
gi|62865869 family with sequence similarity 13, member A1 isofor...   427   e-119
gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens]   242   9e-64
gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo sapi...   242   9e-64
gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens]   137   3e-32
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ...    55   3e-07
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ...    55   3e-07
gi|208022687 GTPase regulator associated with the focal adhesion...    50   8e-06
gi|7662208 GTPase regulator associated with the focal adhesion k...    50   8e-06
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    49   2e-05
gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo sa...    49   2e-05
gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo sa...    49   2e-05
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...    49   2e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    49   2e-05
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    49   2e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    48   4e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    47   5e-05
gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]                    46   1e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       46   2e-04
gi|148762940 DVL-binding protein DAPLE [Homo sapiens]                  45   2e-04
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]             45   3e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    44   4e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     44   4e-04
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    44   4e-04
gi|4758648 kinesin family member 5B [Homo sapiens]                     44   6e-04
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi...    44   6e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    44   6e-04

>gi|156142192 hypothetical protein LOC51306 isoform 3 [Homo sapiens]
          Length = 791

 Score = 1565 bits (4053), Expect = 0.0
 Identities = 791/791 (100%), Positives = 791/791 (100%)

Query: 1   MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60
           MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG
Sbjct: 1   MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60

Query: 61  PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120
           PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE
Sbjct: 61  PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120

Query: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
           EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI
Sbjct: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180

Query: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240
           LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN
Sbjct: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240

Query: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300
           ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY
Sbjct: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300

Query: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360
           LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK
Sbjct: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360

Query: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420
           WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC
Sbjct: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420

Query: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480
           PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL
Sbjct: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480

Query: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540
           QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT
Sbjct: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540

Query: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600
           RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED
Sbjct: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600

Query: 601 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 660
           IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE
Sbjct: 601 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 660

Query: 661 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 720
           IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL
Sbjct: 661 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 720

Query: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780
           LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV
Sbjct: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780

Query: 781 LISKQDSSKSI 791
           LISKQDSSKSI
Sbjct: 781 LISKQDSSKSI 791


>gi|156142190 hypothetical protein LOC51306 isoform 2 [Homo sapiens]
          Length = 887

 Score = 1506 bits (3900), Expect = 0.0
 Identities = 769/791 (97%), Positives = 769/791 (97%), Gaps = 22/791 (2%)

Query: 1   MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60
           MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG
Sbjct: 119 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 178

Query: 61  PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120
           PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE
Sbjct: 179 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 238

Query: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
           EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI
Sbjct: 239 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 298

Query: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240
           LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN
Sbjct: 299 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 358

Query: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300
           ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY
Sbjct: 359 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 418

Query: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360
           LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK
Sbjct: 419 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 478

Query: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420
           WE                      EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC
Sbjct: 479 WE----------------------EPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 516

Query: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480
           PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL
Sbjct: 517 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 576

Query: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540
           QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT
Sbjct: 577 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 636

Query: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600
           RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED
Sbjct: 637 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 696

Query: 601 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 660
           IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE
Sbjct: 697 IKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEE 756

Query: 661 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 720
           IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL
Sbjct: 757 IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPEL 816

Query: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780
           LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV
Sbjct: 817 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 876

Query: 781 LISKQDSSKSI 791
           LISKQDSSKSI
Sbjct: 877 LISKQDSSKSI 887


>gi|156142188 hypothetical protein LOC51306 isoform 1 [Homo sapiens]
          Length = 915

 Score = 1491 bits (3861), Expect = 0.0
 Identities = 769/819 (93%), Positives = 769/819 (93%), Gaps = 50/819 (6%)

Query: 1   MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 60
           MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG
Sbjct: 119 MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEEIWSANSLAAVFG 178

Query: 61  PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 120
           PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE
Sbjct: 179 PDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEE 238

Query: 121 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
           EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI
Sbjct: 239 EEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 298

Query: 181 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 240
           LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN
Sbjct: 299 LERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIADDIIN 358

Query: 241 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 300
           ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY
Sbjct: 359 ASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGCLEREEY 418

Query: 301 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 360
           LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK
Sbjct: 419 LLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLDLKNVSDGDK 478

Query: 361 WEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 420
           W                      EEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC
Sbjct: 479 W----------------------EEPFPAFKSWQEDSESGEAQLSPQAGRMNHHPLEEDC 516

Query: 421 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 480
           PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL
Sbjct: 517 PPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKL 576

Query: 481 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 540
           QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT
Sbjct: 577 QKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQT 636

Query: 541 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 600
           RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED
Sbjct: 637 RPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPED 696

Query: 601 IK----------------------------VTKEERHIVKPLYDRYRLVKQMLTRASITP 632
           IK                            VTKEERHIVKPLYDRYRLVKQMLTRASITP
Sbjct: 697 IKKMTKDHLVEEKASLQKSLLYYESQHGRPVTKEERHIVKPLYDRYRLVKQMLTRASITP 756

Query: 633 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692
           VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS
Sbjct: 757 VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 816

Query: 693 ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN 752
           ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN
Sbjct: 817 ESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRN 876

Query: 753 AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 791
           AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI
Sbjct: 877 AQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 915


>gi|56119110 family with sequence similarity 13, member A1 isoform a
            [Homo sapiens]
          Length = 1023

 Score =  484 bits (1247), Expect = e-136
 Identities = 348/925 (37%), Positives = 492/925 (53%), Gaps = 173/925 (18%)

Query: 1    MQLSQDYNNEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVF 59
            +QL QD  N+ +    LR L+++LP  +Y LLK+LC+FL  VA HH +   + ++LA VF
Sbjct: 138  IQLFQDGRNDVQES-SLRDLIKELPDTHYCLLKYLCQFLTKVAKHHVQNRMNVHNLATVF 196

Query: 60   GPDVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENE------------------EEDF 101
            GP+ FH+   +E MKEQ++ ++IMA +LENY   FE E                  +E +
Sbjct: 197  GPNCFHVPPGLEGMKEQDLCNKIMAKILENYNTLFEVEYTENDHLRCENLARLIIVKEVY 256

Query: 102  SSNDL------------------SSITEQVNELSEEEEEDEKLEHIEELPEEGAEKSNDM 143
              N L                  + I +  +E S +     + E  + +P+     S   
Sbjct: 257  YKNSLPILLTRGLERDMPKPPPKTKIPKSRSEGSIQAHRVLQPELSDGIPQLSLRLSYRK 316

Query: 144  PEVVQLRMTENILESNSVTAT------------STHISPISILPASTDILERTIRAAVEQ 191
              +  +   E  + +  V ++            S H+  +S + A+ ++LERTIR+AVEQ
Sbjct: 317  ACLEDMNSAEGAISAKLVPSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQ 376

Query: 192  HLFDL-----QSSIDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID----- 233
            HLFD+     QSS D +   L   S             + E  H   +G  N+ +     
Sbjct: 377  HLFDVNNSGGQSSEDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGF 436

Query: 234  --IADDIINASESNR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQS 276
              + D I+N  E  +          + SKP    +ST L      QD +   E+  +T+S
Sbjct: 437  NHLDDCILNTQEVEKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRS 496

Query: 277  VGIL----LEPCSD--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEV 330
                     E  SD  +G+ +DG   +     F+S  +         KI +  + ++++ 
Sbjct: 497  HERTGPDDFEWMSDERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQ 543

Query: 331  PGGQSVGVQGEAACVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAF 390
               Q  G Q E+    +P  DL  + D   WE                      EP PAF
Sbjct: 544  QRNQDAGDQEESFVSEVPQSDLTALCDEKNWE----------------------EPIPAF 581

Query: 391  KSWQ-EDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSK 449
             SWQ E+S+S EA LSPQAGR+    L+ED  P+LS R   +GQS+++L D E   S   
Sbjct: 582  SSWQRENSDSDEAHLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPN 641

Query: 450  ALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAA 506
            + SF R R SS  S D+++ED TP QL +++Q   KKIR+FE++FE E+  +PS+SD AA
Sbjct: 642  SHSFMRRRSSSLGSYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAA 701

Query: 507  NPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEP 566
            NP+VLKW  +L K R+Q+K++K K S+ +  P+ R RSNTLPKSFGS L+ EDE+ ++  
Sbjct: 702  NPEVLKWTNDLAKFRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQE-- 759

Query: 567  KVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK------------------------ 602
             ++ K  KPS EATLE I ++L+EKR E   PEDIK                        
Sbjct: 760  -LVDKAIKPSVEATLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESI 818

Query: 603  ----VTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFF 658
                VTK ER ++KPLYDRYRLVKQ+L+RA+  P++GSPS+KRR  +LQPIIEGETA FF
Sbjct: 819  HGRPVTKNERQVMKPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFF 878

Query: 659  EEIKEEEE---DGVNLSSELGDMLKTAVQVQSSLENSESDVE--------ENQEKLALDL 707
            +EIKEEEE   D  N+  +    LKT    +  L+  E D +        +   K + D 
Sbjct: 879  KEIKEEEEGSEDDSNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDT 938

Query: 708  RLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYRE 767
             LS+  AAS+PELLE L + R EKK++RK LR+FE+ F++QNGRN QKEDR P+ EEY E
Sbjct: 939  GLSNLHAASIPELLEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSE 998

Query: 768  YKKIKAKLRLLEVLISKQDS-SKSI 791
            YK IKAKLRLLEVLISK+D+ SKS+
Sbjct: 999  YKHIKAKLRLLEVLISKRDTDSKSM 1023


>gi|62865869 family with sequence similarity 13, member A1 isoform b
           [Homo sapiens]
          Length = 697

 Score =  427 bits (1097), Expect = e-119
 Identities = 295/732 (40%), Positives = 407/732 (55%), Gaps = 123/732 (16%)

Query: 145 EVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDL-----QSS 199
           E++ L+ ++      S    S H+  +S + A+ ++LERTIR+AVEQHLFD+     QSS
Sbjct: 4   EIMPLQSSQEDERPLSPFYLSAHVPQVSNVSATGELLERTIRSAVEQHLFDVNNSGGQSS 63

Query: 200 IDHDLKNLQQQSVVC--------NNEAESIHCDGEGSNNQID-------IADDIINASES 244
            D +   L   S             + E  H   +G  N+ +       + D I+N  E 
Sbjct: 64  EDSESGTLSASSATSARQRRRQSKEQDEVRHGRDKGLINKENTPSGFNHLDDCILNTQEV 123

Query: 245 NR----------DCSKPV---ASTNLDNEAMQQDCV--FENEENTQSVGIL----LEPCS 285
            +          + SKP    +ST L      QD +   E+  +T+S         E  S
Sbjct: 124 EKVHKNTFGCAGERSKPKRQKSSTKLSELHDNQDGLVNMESLNSTRSHERTGPDDFEWMS 183

Query: 286 D--RGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLNANTESEVPGGQSVGVQGEAA 343
           D  +G+ +DG   +     F+S  +         KI +  + ++++    Q  G Q E+ 
Sbjct: 184 DERKGNEKDGGHTQH----FESPTM---------KIQEHPSLSDTKQQRNQDAGDQEESF 230

Query: 344 CVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQ-EDSESGEA 402
              +P  DL  + D   WE                      EP PAF SWQ E+S+S EA
Sbjct: 231 VSEVPQSDLTALCDEKNWE----------------------EPIPAFSSWQRENSDSDEA 268

Query: 403 QLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS 462
            LSPQAGR+    L+ED  P+LS R   +GQS+++L D E   S   + SF R R SS  
Sbjct: 269 HLSPQAGRLIRQLLDEDSDPMLSPRFYAYGQSRQYLDDTEVPPSPPNSHSFMRRRSSSLG 328

Query: 463 SKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTK 519
           S D+++ED TP QL +++Q   KKIR+FE++FE E+  +PS+SD AANP+VLKW  +L K
Sbjct: 329 SYDDEQEDLTPAQLTRRIQSLKKKIRKFEDRFEEEKKYRPSHSDKAANPEVLKWTNDLAK 388

Query: 520 LRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEA 579
            R+Q+K++K K S+ +  P+ R RSNTLPKSFGS L+ EDE+ ++   ++ K  KPS EA
Sbjct: 389 FRRQLKESKLKISEEDLTPRMRQRSNTLPKSFGSQLEKEDEKKQE---LVDKAIKPSVEA 445

Query: 580 TLELILKRLKEKRIERCLPEDIK----------------------------VTKEERHIV 611
           TLE I ++L+EKR E   PEDIK                            VTK ER ++
Sbjct: 446 TLESIQRKLQEKRAESSRPEDIKDMTKDQIANEKVALQKALLYYESIHGRPVTKNERQVM 505

Query: 612 KPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEE---DG 668
           KPLYDRYRLVKQ+L+RA+  P++GSPS+KRR  +LQPIIEGETA FF+EIKEEEE   D 
Sbjct: 506 KPLYDRYRLVKQILSRANTIPIIGSPSSKRRSPLLQPIIEGETASFFKEIKEEEEGSEDD 565

Query: 669 VNLSSELGDMLKTAVQVQSSLENSESDVE--------ENQEKLALDLRLSSSRAASMPEL 720
            N+  +    LKT    +  L+  E D +        +   K + D  LS+  AAS+PEL
Sbjct: 566 SNVKPDFMVTLKTDFSARCFLDQFEDDADGFISPMDDKIPSKCSQDTGLSNLHAASIPEL 625

Query: 721 LEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEV 780
           LE L + R EKK++RK LR+FE+ F++QNGRN QKEDR P+ EEY EYK IKAKLRLLEV
Sbjct: 626 LEHLQEMREEKKRIRKKLRDFEDNFFRQNGRNVQKEDRTPMAEEYSEYKHIKAKLRLLEV 685

Query: 781 LISKQDS-SKSI 791
           LISK+D+ SKS+
Sbjct: 686 LISKRDTDSKSM 697


>gi|50897856 hypothetical protein LOC220965 isoform 1 [Homo sapiens]
          Length = 585

 Score =  242 bits (618), Expect = 9e-64
 Identities = 164/424 (38%), Positives = 238/424 (56%), Gaps = 47/424 (11%)

Query: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440
           D  +P P  K  Q +++S    L S    R+ +H  + D  P+LS R   F QSQRF  D
Sbjct: 195 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 253

Query: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497
           PE   S      F   R SS  S  + +E +T  QL K +Q   +KIR+FEE+FE+E+  
Sbjct: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313

Query: 498 KPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NTLPKSF 551
           +PS+ D  +NP+VLKWM +L K RKQ+K+ K K S+ +   P+  PR+      T+P+  
Sbjct: 314 RPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPREN 373

Query: 552 GSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIV 611
           G            +P+    E   S E T +  L  LKE+R +    ED KVTK++++++
Sbjct: 374 G------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLI 421

Query: 612 KPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEED 667
           KPLYDRYR++KQ+L+  S+ P +     S   + +G   QP +    +H          D
Sbjct: 422 KPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGD 474

Query: 668 GVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKA 727
            +  S+E          V++ L + + +V+         L +S+   A+MP LL+ L + 
Sbjct: 475 HLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRET 521

Query: 728 RAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787
           RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD 
Sbjct: 522 RADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDV 581

Query: 788 SKSI 791
           +K+I
Sbjct: 582 AKTI 585


>gi|219555642 hypothetical protein LOC220965 isoform 3 [Homo
           sapiens]
          Length = 502

 Score =  242 bits (618), Expect = 9e-64
 Identities = 164/424 (38%), Positives = 238/424 (56%), Gaps = 47/424 (11%)

Query: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440
           D  +P P  K  Q +++S    L S    R+ +H  + D  P+LS R   F QSQRF  D
Sbjct: 112 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 170

Query: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497
           PE   S      F   R SS  S  + +E +T  QL K +Q   +KIR+FEE+FE+E+  
Sbjct: 171 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 230

Query: 498 KPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGE-FVPQTRPRS-----NTLPKSF 551
           +PS+ D  +NP+VLKWM +L K RKQ+K+ K K S+ +   P+  PR+      T+P+  
Sbjct: 231 RPSHGDKTSNPEVLKWMNDLAKGRKQLKELKLKLSEEQGSAPKGPPRNLLCEQPTVPREN 290

Query: 552 GSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIV 611
           G            +P+    E   S E T +  L  LKE+R +    ED KVTK++++++
Sbjct: 291 G------------KPEAAGPEPSSSGEETPDAALTCLKERREQLPPQEDSKVTKQDKNLI 338

Query: 612 KPLYDRYRLVKQMLTRASITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEED 667
           KPLYDRYR++KQ+L+  S+ P +     S   + +G   QP +    +H          D
Sbjct: 339 KPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGD 391

Query: 668 GVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKA 727
            +  S+E          V++ L + + +V+         L +S+   A+MP LL+ L + 
Sbjct: 392 HLTYSNE-------TEPVRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRET 438

Query: 728 RAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787
           RA+KK+LRK LREFEE F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD 
Sbjct: 439 RADKKRLRKALREFEEQFFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDV 498

Query: 788 SKSI 791
           +K+I
Sbjct: 499 AKTI 502


>gi|50897854 hypothetical protein LOC220965 isoform 2 [Homo sapiens]
          Length = 487

 Score =  137 bits (346), Expect = 3e-32
 Identities = 89/227 (39%), Positives = 134/227 (59%), Gaps = 28/227 (12%)

Query: 573 KKPSKEATLELILKRLKEK--RIERCLPEDIK--VTKEERHIVKPLYDRYRLVKQMLTRA 628
           K+P     L   ++ LK K  + E    ++ K  VTK++++++KPLYDRYR++KQ+L+  
Sbjct: 281 KEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKYRVTKQDKNLIKPLYDRYRIIKQILSTP 340

Query: 629 SITPVL----GSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQ 684
           S+ P +     S   + +G   QP +    +H          D +  S+E          
Sbjct: 341 SLIPTIQEEEDSDEDRPQGSQ-QPSLADPASHL------PVGDHLTYSNE-------TEP 386

Query: 685 VQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEA 744
           V++ L + + +V+         L +S+   A+MP LL+ L + RA+KK+LRK LREFEE 
Sbjct: 387 VRALLPDEKKEVKPPA------LSMSNLHEATMPVLLDHLRETRADKKRLRKALREFEEQ 440

Query: 745 FYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSKSI 791
           F++Q GR+ QKEDR+P+ +EY EYK IKAKLRLLEVLISKQD +K+I
Sbjct: 441 FFKQTGRSPQKEDRIPMADEYYEYKHIKAKLRLLEVLISKQDVAKTI 487



 Score = 78.2 bits (191), Expect = 3e-14
 Identities = 71/239 (29%), Positives = 109/239 (45%), Gaps = 31/239 (12%)

Query: 382 DGEEPFPAFKSWQEDSESGEAQL-SPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHD 440
           D  +P P  K  Q +++S    L S    R+ +H  + D  P+LS R   F QSQRF  D
Sbjct: 195 DSADPSPVHKDGQNEADSAPEDLHSVGTSRLLYHITDGD-NPLLSPRCSIFSQSQRFNLD 253

Query: 441 PEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQ---KKIRQFEEQFERERNS 497
           PE   S      F   R SS  S  + +E +T  QL K +Q   +KIR+FEE+FE+E+  
Sbjct: 254 PESAPSPPSTQQFMMPRSSSRCSCGDGKEPQTITQLTKHIQSLKRKIRKFEEKFEQEKKY 313

Query: 498 KPSYSD------IAANPKVLKWMTELTKLRKQIKDAKHKNSD---GEFVPQTRPRSNTLP 548
           + +  D      +    +++K +     L   I++ +  + D   G   P     ++ LP
Sbjct: 314 RVTKQDKNLIKPLYDRYRIIKQILSTPSLIPTIQEEEDSDEDRPQGSQQPSLADPASHLP 373

Query: 549 KSFGSSLDHEDEENEDEP--KVIQKEKKPSK----------EATLELILKRLKEKRIER 595
                  DH    NE EP   ++  EKK  K          EAT+ ++L  L+E R ++
Sbjct: 374 VG-----DHLTYSNETEPVRALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK 427



 Score = 32.0 bits (71), Expect = 2.3
 Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 4/69 (5%)

Query: 436 RFLHDPEKLDSSSKALSFTRIRRSSFSSK-DEKREDRTPYQLVKKLQKKIRQFEEQFERE 494
           R L   EK +    ALS + +  ++     D  RE R      K+L+K +R+FEEQF ++
Sbjct: 388 RALLPDEKKEVKPPALSMSNLHEATMPVLLDHLRETRADK---KRLRKALREFEEQFFKQ 444

Query: 495 RNSKPSYSD 503
               P   D
Sbjct: 445 TGRSPQKED 453


>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 65/295 (22%), Positives = 128/295 (43%), Gaps = 29/295 (9%)

Query: 442 EKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSY 501
           EK+   +K ++     +S+  S + K +++      KKL K  +  EE   +E+ ++   
Sbjct: 342 EKIHEDTKEIN----EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEEN--KEKFTQLDL 395

Query: 502 SDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVP--------QTRPRSNTLPKSFGS 553
            D+    K+    ++  KL KQ++  K K  + + +P        +T  R+N L K    
Sbjct: 396 EDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEK 455

Query: 554 S---LDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHI 610
               L    +  + E + +QKEK+ S+E  L    K + E R +      + V + E  I
Sbjct: 456 EEKKLKEVMDSLKQETQGLQKEKE-SREKELMGFSKSVNEARSK------MDVAQSELDI 508

Query: 611 VKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVN 670
                 R+      LT+A    +  S + K R   ++ I EG+     +E+KE+E++   
Sbjct: 509 Y---LSRHNTAVSQLTKAKEALIAASETLKERKAAIRDI-EGKLPQTEQELKEKEKELQK 564

Query: 671 LSSELGDMLKTAVQVQSSLENSESDVEENQEK-LALDLRLSSSRAASMPELLEQL 724
           L+ E  +       +   +E ++S +  N+ +   LD  +   ++  +P +  +L
Sbjct: 565 LTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRL 619



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 12/146 (8%)

Query: 650 IEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLA-LDLR 708
           +E +     E+ KE  E    LS+E+    K     +  L      +EEN+EK   LDL 
Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLE 396

Query: 709 LSSSRAASMPELLEQLWKARAEKKKLRKTL---REFEEAFYQQNGRNAQKEDRVPVLEEY 765
               R        E+L  A ++ KKL K L   +E  E F     ++    +        
Sbjct: 397 DVQVR--------EKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNA 448

Query: 766 REYKKIKAKLRLLEVLISKQDSSKSI 791
            E +K K + +L EV+ S +  ++ +
Sbjct: 449 LEKEKEKEEKKLKEVMDSLKQETQGL 474


>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
           [Homo sapiens]
          Length = 1288

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 65/295 (22%), Positives = 128/295 (43%), Gaps = 29/295 (9%)

Query: 442 EKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSY 501
           EK+   +K ++     +S+  S + K +++      KKL K  +  EE   +E+ ++   
Sbjct: 342 EKIHEDTKEIN----EKSNILSNEMKAKNKDVKDTEKKLNKITKFIEEN--KEKFTQLDL 395

Query: 502 SDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVP--------QTRPRSNTLPKSFGS 553
            D+    K+    ++  KL KQ++  K K  + + +P        +T  R+N L K    
Sbjct: 396 EDVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEK 455

Query: 554 S---LDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHI 610
               L    +  + E + +QKEK+ S+E  L    K + E R +      + V + E  I
Sbjct: 456 EEKKLKEVMDSLKQETQGLQKEKE-SREKELMGFSKSVNEARSK------MDVAQSELDI 508

Query: 611 VKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVN 670
                 R+      LT+A    +  S + K R   ++ I EG+     +E+KE+E++   
Sbjct: 509 Y---LSRHNTAVSQLTKAKEALIAASETLKERKAAIRDI-EGKLPQTEQELKEKEKELQK 564

Query: 671 LSSELGDMLKTAVQVQSSLENSESDVEENQEK-LALDLRLSSSRAASMPELLEQL 724
           L+ E  +       +   +E ++S +  N+ +   LD  +   ++  +P +  +L
Sbjct: 565 LTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLDAIIQEKKSGRIPGIYGRL 619



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 37/146 (25%), Positives = 60/146 (41%), Gaps = 12/146 (8%)

Query: 650 IEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLA-LDLR 708
           +E +     E+ KE  E    LS+E+    K     +  L      +EEN+EK   LDL 
Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLE 396

Query: 709 LSSSRAASMPELLEQLWKARAEKKKLRKTL---REFEEAFYQQNGRNAQKEDRVPVLEEY 765
               R        E+L  A ++ KKL K L   +E  E F     ++    +        
Sbjct: 397 DVQVR--------EKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTTRNNA 448

Query: 766 REYKKIKAKLRLLEVLISKQDSSKSI 791
            E +K K + +L EV+ S +  ++ +
Sbjct: 449 LEKEKEKEEKKLKEVMDSLKQETQGL 474


>gi|208022687 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform b [Homo sapiens]
          Length = 759

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 41/173 (23%), Positives = 75/173 (43%), Gaps = 21/173 (12%)

Query: 9   NEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEE-IWSANSLAAVFGPDVFHIY 67
           N++    ++  L+ +LP  N  +L+ L   LANVA++H++ + +  +L  VFGP +    
Sbjct: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540

Query: 68  TD----VEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEED 123
            +    + D+K Q IV  I+           EN E+ F++     +T     LS ++  D
Sbjct: 541 EETVAAIMDIKFQNIVIEIL----------IENHEKIFNTVPDMPLTNAQLHLSRKKSSD 590

Query: 124 EKLEHIEELP------EEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISP 170
            K     E P       +  EK      ++   +       NS+  +S+ + P
Sbjct: 591 SKPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQP 643


>gi|7662208 GTPase regulator associated with the focal adhesion
           kinase pp125 isoform a [Homo sapiens]
          Length = 814

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 41/173 (23%), Positives = 75/173 (43%), Gaps = 21/173 (12%)

Query: 9   NEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASHHEE-IWSANSLAAVFGPDVFHIY 67
           N++    ++  L+ +LP  N  +L+ L   LANVA++H++ + +  +L  VFGP +    
Sbjct: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540

Query: 68  TD----VEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEED 123
            +    + D+K Q IV  I+           EN E+ F++     +T     LS ++  D
Sbjct: 541 EETVAAIMDIKFQNIVIEIL----------IENHEKIFNTVPDMPLTNAQLHLSRKKSSD 590

Query: 124 EKLEHIEELP------EEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISP 170
            K     E P       +  EK      ++   +       NS+  +S+ + P
Sbjct: 591 SKPPSCSERPLTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQP 643


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 62/314 (19%), Positives = 138/314 (43%), Gaps = 20/314 (6%)

Query: 477 VKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQI-----KDAKHKN 531
           +++ ++KIR+ EE+  R+        +     + + W  E  K+R+Q      K+ K + 
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKIRE 442

Query: 532 SDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEK 591
            + +   Q + R     +     +  +++  E E K+ ++E+K  ++   E  ++  +EK
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ---EEKIREQEEK 499

Query: 592 --RIERCLPEDIKVTKEE-RHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQP 648
             R E  + E  K+ +EE R   + ++ +   +++          +     K R Q  + 
Sbjct: 500 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKM 559

Query: 649 IIEGETAHFFEE-IKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDL 707
             + E  H  EE I+E+EE       ++ +  +   + +  +   E   +E +EK+    
Sbjct: 560 WRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE 619

Query: 708 RLSSSRAASMPELLEQLW----KARAEKKKLRKT---LREFEEAFYQQNGRNAQKEDRVP 760
                +   M E  E++     K R ++KK+R+    +RE EE   +Q  +  ++E+++ 
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 679

Query: 761 VLEEYREYKKIKAK 774
             EE  + ++ K +
Sbjct: 680 EQEEKMQEQEEKMR 693



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 52/339 (15%), Positives = 147/339 (43%), Gaps = 26/339 (7%)

Query: 455 RIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQ-FERERNSKPSYSDIAANPKVLKW 513
           +IR      ++++ + R   +++ + ++K+R+ EE  +E+E   +     +    + ++ 
Sbjct: 383 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 442

Query: 514 MTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSS---LDHEDEENEDEPKVIQ 570
           + E    +++I++ + K  + E + +   R     K +       + E++  E E K+ +
Sbjct: 443 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWR 502

Query: 571 KEKKPSKEATLELILKRLKEKRI-----------------ERCLPEDIKVTKEERHIVKP 613
           +E+K  ++  +    KR +++ +                 E+   ++ K+ K+E  + + 
Sbjct: 503 QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQ 562

Query: 614 ---LYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGE--TAHFFEEIKEEEEDG 668
              ++D+   +++   +            ++  +  + I E E  T    E++ E+EE  
Sbjct: 563 EEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM 622

Query: 669 VNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKAR 728
                ++ +  +   + +  +   E  + E +EK+     +   +   M E  E++ +  
Sbjct: 623 CEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 682

Query: 729 AEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYRE 767
            + ++  + +R  EE  ++Q  R  Q+E+++   +E+ E
Sbjct: 683 EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 721



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 47/236 (19%), Positives = 109/236 (46%), Gaps = 23/236 (9%)

Query: 559 DEENEDEPKVIQKEKK--PSKEATLELILKRLKEK--RIERCLPEDIKVTKEERHIVKPL 614
           DEE +++   +Q++ +   S+++ ++L +K LK K  R +  LP+  ++  E  H+ K L
Sbjct: 277 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKEL 335

Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674
                 ++  +    +   L     ++  +  + I E E     E+I+E+EE       +
Sbjct: 336 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE-----EKIQEQEE-------K 383

Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
           + +  +   + +  +   E  + E +EK+     +   +   M    E +W+   + ++L
Sbjct: 384 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 443

Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYK----KIKAKLRLLEVLISKQD 786
            + + E E+   Q+  R  Q+E+++   E+ +E +    + + K+R  E  I +Q+
Sbjct: 444 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497



 Score = 31.2 bits (69), Expect = 3.9
 Identities = 21/87 (24%), Positives = 40/87 (45%), Gaps = 5/87 (5%)

Query: 66  IYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEE---- 121
           ++   E ++EQE   R     +    E  + +EE     +   + EQ  ++ E+EE    
Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQE-EKMCEQEEKMQEQEEKMRR 638

Query: 122 EDEKLEHIEELPEEGAEKSNDMPEVVQ 148
           ++EK+   E+   E  EK  +  E++Q
Sbjct: 639 QEEKIREQEKKIREQEEKIREQEEMMQ 665


>gi|111154090 Rho GTPase activating protein 24 isoform 3 [Homo
           sapiens]
          Length = 653

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 8/98 (8%)

Query: 8   NNEDEFG-RKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFH 65
           + E+E G ++L   ++ LP VNY+LLK++CRFL  V S+      S  +LA VFGP++  
Sbjct: 144 SKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI-- 201

Query: 66  IYTDVED----MKEQEIVSRIMAGLLENYYEFFENEEE 99
           +   VED    M+   +V ++M+ ++  +   F  + E
Sbjct: 202 LRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAE 239


>gi|111154099 Rho GTPase activating protein 24 isoform 2 [Homo
           sapiens]
          Length = 655

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 8/98 (8%)

Query: 8   NNEDEFG-RKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFH 65
           + E+E G ++L   ++ LP VNY+LLK++CRFL  V S+      S  +LA VFGP++  
Sbjct: 146 SKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI-- 203

Query: 66  IYTDVED----MKEQEIVSRIMAGLLENYYEFFENEEE 99
           +   VED    M+   +V ++M+ ++  +   F  + E
Sbjct: 204 LRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAE 241


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 33/98 (33%), Positives = 56/98 (57%), Gaps = 8/98 (8%)

Query: 8   NNEDEFG-RKLRFLLQQLPPVNYSLLKFLCRFLANVASHH-EEIWSANSLAAVFGPDVFH 65
           + E+E G ++L   ++ LP VNY+LLK++CRFL  V S+      S  +LA VFGP++  
Sbjct: 239 SKEEEAGVKELAKQVKSLPVVNYNLLKYICRFLDEVQSYSGVNKMSVQNLATVFGPNI-- 296

Query: 66  IYTDVED----MKEQEIVSRIMAGLLENYYEFFENEEE 99
           +   VED    M+   +V ++M+ ++  +   F  + E
Sbjct: 297 LRPKVEDPLTIMEGTVVVQQLMSVMISKHDCLFPKDAE 334


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 63/278 (22%), Positives = 112/278 (40%), Gaps = 34/278 (12%)

Query: 426 HRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS---SKDEKREDRTPYQLVKKLQK 482
           HRS    +S+    D  +  S  K  S +R RR S S   S+D++++ R   +  +++++
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 392

Query: 483 KIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRP 542
           K R+ E + E+ER                          K+ +  K+K+ D E   + R 
Sbjct: 393 KDREKEREREKERE-------------------------KEKERGKNKDRDKER-EKDRE 426

Query: 543 RSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK 602
           +     +      +HE + ++++ K   KEK+  K+ + E+  KR K+K+  R  P    
Sbjct: 427 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTPPRSYN 485

Query: 603 VTKEERHIVKPLYDRYRLVKQMLTRASIT---PVLGSPSTKRRGQMLQPIIEGETAHFFE 659
            ++  R   +    R         R S T       SPS + R +      E E  H  E
Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK-DKKREKERDHISE 544

Query: 660 EIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
             + E    +  SS   D  +   +  +SL+  E + E
Sbjct: 545 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 582


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 63/278 (22%), Positives = 112/278 (40%), Gaps = 34/278 (12%)

Query: 426 HRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFS---SKDEKREDRTPYQLVKKLQK 482
           HRS    +S+    D  +  S  K  S +R RR S S   S+D++++ R   +  +++++
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 276

Query: 483 KIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRP 542
           K R+ E + E+ER                          K+ +  K+K+ D E   + R 
Sbjct: 277 KDREKEREREKERE-------------------------KEKERGKNKDRDKER-EKDRE 310

Query: 543 RSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIK 602
           +     +      +HE + ++++ K   KEK+  K+ + E+  KR K+K+  R  P    
Sbjct: 311 KDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKK-SRTPPRSYN 369

Query: 603 VTKEERHIVKPLYDRYRLVKQMLTRASIT---PVLGSPSTKRRGQMLQPIIEGETAHFFE 659
            ++  R   +    R         R S T       SPS + R +      E E  H  E
Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKK-DKKREKERDHISE 428

Query: 660 EIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
             + E    +  SS   D  +   +  +SL+  E + E
Sbjct: 429 RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKE 466


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 59/335 (17%), Positives = 145/335 (43%), Gaps = 75/335 (22%)

Query: 464 KDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQ 523
           ++EK ++R   + +++ ++KIR+ EE+  R+        +     + + W  E     ++
Sbjct: 293 QEEKIQERE--EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-----EK 345

Query: 524 IKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL 583
           I++ + K  + E + +                  ++E+ ++E K+ ++EK+  +EA +  
Sbjct: 346 IRELEEKMHEQEKIRE------------------QEEKRQEEEKIREQEKRQEQEAKMWR 387

Query: 584 ILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRG 643
             ++++E+  +    E++   +EE+                                  G
Sbjct: 388 QEEKIREQEEKIREQEEMMQEQEEK---------------------------------MG 414

Query: 644 QMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKL 703
           +  + + E E     EE++E+EE       ++ +  K   + +  +   E  ++E +EK+
Sbjct: 415 EQEEKMWEQE-----EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469

Query: 704 ALDLRLSSSRAASMPELLEQL----WKARAEKKKLR---KTLREFEEAFYQQNGRNAQKE 756
                    + A M E  E++     K R ++KK+R   + +RE EE   +Q  +  ++E
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE 529

Query: 757 DRV-----PVLEEYREYKKIKAKLRLLEVLISKQD 786
           +++      + E+  + ++ + K+R  EV + +Q+
Sbjct: 530 EKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQE 564



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 45/236 (19%), Positives = 102/236 (43%), Gaps = 44/236 (18%)

Query: 559 DEENEDEPKVIQKEKK--PSKEATLELILKRLKEK--RIERCLPEDIKVTKEERHIVKPL 614
           DEE +++   +Q++ +   S+++ ++L +K LK K  R +  LP+  ++  E  H+ K L
Sbjct: 204 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKEL 262

Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674
                                S S K + Q+       E    +  + +++E+ +    E
Sbjct: 263 Q--------------------SVSAKLQAQV-------EENELWNRLNQQQEEKMWRQEE 295

Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
                    + +  ++  E  + E +EK+     +   +   M    E +W+   + ++L
Sbjct: 296 ------KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 349

Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYK----KIKAKLRLLEVLISKQD 786
            + + E E+   Q+  R  Q+E+++   E+ +E +    + + K+R  E  I +Q+
Sbjct: 350 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 403



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 71  EDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEE----EDEKL 126
           E ++EQE   R     +    E  + +EE     +   + EQ  ++ E+EE    ++EK+
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE-GKMCEQEAKMQEQEEKMRRQEEKI 497

Query: 127 EHIEELPEEGAEKSNDMPEVVQ 148
              E+   E  EK  +  E++Q
Sbjct: 498 REQEKKIREQEEKIREQEEMMQ 519


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 64/345 (18%), Positives = 146/345 (42%), Gaps = 33/345 (9%)

Query: 434 SQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFER 493
           ++R+  D +  +S         ++R +F+  D++  +      VKK   +++   ++ + 
Sbjct: 81  TKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQE 140

Query: 494 ERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGS 553
           + N K +Y+                  RK++   K     GE   Q RP ++ L ++   
Sbjct: 141 KMNEK-NYT-----------------FRKRVVIKKPWLRLGEVTAQKRPENSLLEETL-- 180

Query: 554 SLDHEDEENEDEPKVIQKEKKPSKEATLELIL-KRLKEKRIERCLPEDIKVTKEERHIVK 612
             DH         K+ ++   PS E     I  + LKEK  E  L E +++ + E+  ++
Sbjct: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAE--LQEKLRLVESEKSEIQ 238

Query: 613 PLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLS 672
                 + +K+ L RA +  +L     +     L   ++  +A    +++E E   +   
Sbjct: 239 L---NVKDLKRKLERAQL--LLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293

Query: 673 SELGDMLKTAVQVQSSLEN---SESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARA 729
            +   M +   ++Q   E     E  + E +EK+         +   + E  +++W+   
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEE 353

Query: 730 EKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEE--YREYKKIK 772
           + ++  + +RE EE  ++Q  +  ++++++   EE  +R+ +KI+
Sbjct: 354 KIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIR 398



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 45/232 (19%), Positives = 110/232 (47%), Gaps = 24/232 (10%)

Query: 557 HEDEEN--EDEPKVIQKEKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPL 614
           HE EE   E E K+ ++E+K  ++       ++++E+  E+   ++ K+ +++  I +  
Sbjct: 335 HEQEEKIREQEDKMWRQEEKIREQE------EKIREQE-EKMWRQEEKIREQDEKIQEQE 387

Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674
            + +R  +++  +            KR+ +M +   E +     E+I+E+EE+      +
Sbjct: 388 EEMWRQEEKIREQEE----------KRQEKMWRQ--EKKMREQDEKIREQEEEMWRQEEK 435

Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
           + ++ +     +  L   E  ++E +EK+         +   + E  E+ W+     K+ 
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQE 495

Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQD 786
            K + E EE  ++Q  +  ++E+++   EE  + ++ + K+R  EV + +Q+
Sbjct: 496 EK-IWEQEEKMWRQEEKMWEQEEKMQEQEE--KMQRQEEKMREQEVRLWQQE 544



 Score = 35.0 bits (79), Expect = 0.27
 Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 8/93 (8%)

Query: 71  EDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEE-EEEDEKLEHI 129
           ++ K QE + R    + E   +  E EEE +         E++ EL E  ++++EKL  +
Sbjct: 400 QEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQE------EKIRELEEMMQDQEEKLREV 453

Query: 130 EELPEEGAEKSNDMPEVVQLRMTENILESNSVT 162
           EE  +E  EK  +  E +Q R  E I E    T
Sbjct: 454 EEKMQEEEEKMQEQEEKIQ-RQEEKIQEQEEKT 485



 Score = 34.7 bits (78), Expect = 0.35
 Identities = 51/299 (17%), Positives = 128/299 (42%), Gaps = 25/299 (8%)

Query: 469 EDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQ---IK 525
           E+   + L+ + Q++    +E+  +E+  K    ++    +  K   +  K+ +Q   I+
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIR 342

Query: 526 DAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELIL 585
           + + K    E   + R +   + +        E++  E + K+ ++E++  ++   E  +
Sbjct: 343 EQEDKMWRQE--EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQ---EEKI 397

Query: 586 KRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQM 645
           +  +EKR E+   ++ K+ +++  I +   + +R  +++               +   +M
Sbjct: 398 REQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKI---------------RELEEM 442

Query: 646 LQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLAL 705
           +Q   + E     EE  +EEE+ +    E     +  +Q Q      +  + + +EK+  
Sbjct: 443 MQD--QEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWE 500

Query: 706 DLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEE 764
                  +   M E  E++ +   + ++  + +RE E   +QQ  +  ++E R+  LEE
Sbjct: 501 QEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEE 559


>gi|46049114 M-phase phosphoprotein 1 [Homo sapiens]
          Length = 1780

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 60/332 (18%), Positives = 146/332 (43%), Gaps = 31/332 (9%)

Query: 476  LVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKH------ 529
            ++ KL++ +++F+E  +   +S  +  D+  N K LK   E+T+L   ++D KH      
Sbjct: 1153 IILKLERNLKEFQEHLQ---DSVKNTKDL--NVKELKLKEEITQLTNNLQDMKHLLQLKE 1207

Query: 530  -----KNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELI 584
                    + E + +    S+   ++  + L  ++E+  D  + +   KK  K+   E+ 
Sbjct: 1208 EEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVS 1267

Query: 585  LKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRG- 643
            + R ++K +   + E   + K++    + L  + R ++Q+  + +   V  +     R  
Sbjct: 1268 VMRDEDKLLRIKINE---LEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERAC 1324

Query: 644  ---QMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQ 700
                + + IIE       E+ + + E    L ++L ++ + A +++   E       +N 
Sbjct: 1325 KDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNN 1384

Query: 701  EKLALDLRLSSSRAASMPELLEQL----WKARAEKKK-LRKTLREFEEAFYQQNGRNAQK 755
            ++   +   ++     +  L ++L     K  A++KK L + +    +A   +N RN + 
Sbjct: 1385 QRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNKEM 1444

Query: 756  EDRVPVLEEYREYKKIKAKLRLLEVLISKQDS 787
            +      E+   + K + ++ +L   ++++DS
Sbjct: 1445 K---KYAEDRERFFKQQNEMEILTAQLTEKDS 1473


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 56/312 (17%), Positives = 138/312 (44%), Gaps = 17/312 (5%)

Query: 475 QLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDG 534
           +L ++ +++ ++ +E  ER++   P+ +D + +    +   +  +     K+ K ++   
Sbjct: 99  RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQE 158

Query: 535 EFVPQTRPRSNTLPKSFGSS--LDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKR 592
            +  +    + T+ KS+  +   D E+ + ED+ K  ++E+KP + +  E  ++ + E++
Sbjct: 159 RYEIE---ETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEK 215

Query: 593 IERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEG 652
                 E + ++ +   I      +    +Q     S    +     K R +  +  +E 
Sbjct: 216 TTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKM-EEEDKERAEAERARLEA 274

Query: 653 ETAHFFEEIKEEEEDGV-NLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALD----L 707
           E     E IK E++  + +  + +    K A Q +   E  E +    +EK A +    +
Sbjct: 275 EER---ERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRI 331

Query: 708 RLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYRE 767
           +    RAA   + +++  K  AE+   R+ ++E E+   ++  R   +E+    +EE + 
Sbjct: 332 KEEEKRAAEERQRIKEEEKRAAEE---RQRIKEEEKRAAEERQRARAEEEEKAKVEEQKR 388

Query: 768 YKKIKAKLRLLE 779
            K+++ K   ++
Sbjct: 389 NKQLEEKKHAMQ 400



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 78/432 (18%), Positives = 166/432 (38%), Gaps = 54/432 (12%)

Query: 391 KSWQEDSESGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKA 450
           K  +ED E  EA+ +            E    +   R+    + +    + E+ ++  + 
Sbjct: 256 KMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERE 315

Query: 451 LSFTRIRRSSFSS---KDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAAN 507
                 +R++      K+E++      Q +K+ +K+  +  ++ + E          A  
Sbjct: 316 RMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA 375

Query: 508 PKVLKWMTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENED--E 565
            +  K   E  K  KQ+++ KH       + +T+ +   + +       +E +  ED  +
Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHA------MQETKIKGEKVEQKIEGKWVNEKKAQEDKLQ 429

Query: 566 PKVIQK---EKKPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVK 622
             V++K   EK    +A  E + +     + E    E IK  KE +  VK   DR     
Sbjct: 430 TAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDR----- 484

Query: 623 QMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFE------EIKEEEEDGVNLSSELG 676
               +   T V       + G+ +   ++  T + F        +  +E +G     E G
Sbjct: 485 ----KKGFTEV-----KSQNGEFMTHKLK-HTENTFSRPGGRASVDTKEAEGAP-QVEAG 533

Query: 677 DMLKTAVQVQSSLENSESD-VEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLR 735
             L+   + +   E+ E + +++ Q++ AL+L     +     ++LE+  + R +++  R
Sbjct: 534 KRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADR 593

Query: 736 KTLREFE-----EAFYQQNGRNAQKEDRVP---VLEEYREYK---------KIKAKLRLL 778
           K   E E     E   ++    A+K  ++P   + ++ + +K         KI+ +   L
Sbjct: 594 KLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFL 653

Query: 779 EVLISKQDSSKS 790
              + K    KS
Sbjct: 654 NKSVQKSSGVKS 665



 Score = 30.4 bits (67), Expect = 6.7
 Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 14/98 (14%)

Query: 74  KEQEIVSRIMAGLLENYYEFFENEE--EDFSSNDLSSITEQVNELSEEEEEDEKLEHIEE 131
           KE++  SR      +  YE  E E   + +  ND     E   E  E+EEE+      EE
Sbjct: 149 KEEKSESR------QERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEE------EE 196

Query: 132 LPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHIS 169
            P+ G+   N +  +V+ + TE+  E+  ++  +  IS
Sbjct: 197 KPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQIS 234


>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
          Length = 2028

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 62/269 (23%), Positives = 109/269 (40%), Gaps = 38/269 (14%)

Query: 479 KLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKH--KNSDGEF 536
           +L KKI + + Q ERE+ S      ++          EL + ++Q++      K      
Sbjct: 505 QLSKKIEKLQTQLEREKQSNQDLETLS---------EELIREKEQLQSDMETLKADKARQ 555

Query: 537 VPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERC 596
           +       + L ++  S  +     +E   K ++KE K   +   E   K  + +  +R 
Sbjct: 556 IKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQ 615

Query: 597 LPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 656
           L  D++  KE+        +R   +++ L R            +  G++ + +   ETA 
Sbjct: 616 LHRDLEQAKEKG-------ERAEKLERELQRLQ----------EENGRLARKVTSLETAT 658

Query: 657 FFEEIKEEEEDGVNLSSE-LGDMLKTAVQVQSSLENSESDVE----ENQE--KLALDLRL 709
              E  E E  G+ L +  L   L T   V   LE  E D +    EN E  +L   +R 
Sbjct: 659 EKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRF 718

Query: 710 SSSRAASMPELLEQLWKARAEKKKLRKTL 738
           +S++ A M    +QL     EK++LRK +
Sbjct: 719 TSTKLAQMERENQQL---EREKEELRKNV 744


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 32/122 (26%), Positives = 58/122 (47%), Gaps = 3/122 (2%)

Query: 9   NEDEFGRKLRFLLQQLPPVNYSLLKFLCRFLANVASH-HEEIWSANSLAAVFGPDVF--H 65
           +E E   +L   +  LP  NY+LL+++C+FL  V ++ +    S  +LA VFGP++    
Sbjct: 261 DEGEGTLELAKQVSNLPQANYNLLRYICKFLDEVQAYSNVNKMSVQNLATVFGPNILRPQ 320

Query: 66  IYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEK 125
           +   V  M+   +V  +M  L+  + + F     +  ++    +   V   SEE   D +
Sbjct: 321 VEDPVTIMEGTSLVQHLMTVLIRKHSQLFTAPVPEGPTSPRGGLQCAVGWGSEEVTRDSQ 380

Query: 126 LE 127
            E
Sbjct: 381 GE 382


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 61/335 (18%), Positives = 150/335 (44%), Gaps = 34/335 (10%)

Query: 455 RIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQ-FERERNSKPSYSDIAANPKVLKW 513
           +IR      ++++ + R   +++ + ++K+R+ EE  +E+E   +     +    + ++ 
Sbjct: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRE 381

Query: 514 MTELTKLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEK 573
           + E    +++I++ + K  + E + +   R     K +      E++  E E K+ ++EK
Sbjct: 382 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ----EEKIREQEEKIREQEK 437

Query: 574 KPSKEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPV 633
           K  ++   E I ++ K +  E+   ++    +EE+  ++   + +R  ++M  +  I   
Sbjct: 438 KMWRQE--EKIHEQEKIREEEKRQEQEEMWRQEEK--IREQEEIWRQKEKMHEQEKI--- 490

Query: 634 LGSPSTKRRGQMLQPIIEGETAHFFEE-IKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692
                   R Q  +   + E  H  EE I+E+EE       ++ +  +   + +  +   
Sbjct: 491 --------RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQ 542

Query: 693 ESDVEENQEKLALD---LRLSSSRAASMPELLEQLWKARAEKKKLRKT----------LR 739
           E  ++E +EK+      ++          ++ EQ  K R +K+K+R+           +R
Sbjct: 543 EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIR 602

Query: 740 EFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIKAK 774
           E EE   +Q  +  ++E+++   EE  + ++ K +
Sbjct: 603 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 637



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 48/236 (20%), Positives = 110/236 (46%), Gaps = 23/236 (9%)

Query: 559 DEENEDEPKVIQKEKK--PSKEATLELILKRLKEK--RIERCLPEDIKVTKEERHIVKPL 614
           DEE +++   +Q++ +   S+++ ++L +K LK K  R +  LP+  ++  E  H+ K L
Sbjct: 216 DEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ-QLQAEADHLGKEL 274

Query: 615 YDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSE 674
                 ++  +    +   L     ++  +  + I E E     E+I+E+EE       +
Sbjct: 275 QSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE-----EKIQEQEE-------K 322

Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
           + +  +   + +  +   E  + E +EK+     +   +   M  L E +W+   + ++L
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382

Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYK----KIKAKLRLLEVLISKQD 786
            + + E E+   Q+  R  Q+E+++   E+ +E +    + + K+R  E  I +Q+
Sbjct: 383 EEKMHEQEKIREQEEKR--QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 436


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 79/393 (20%), Positives = 153/393 (38%), Gaps = 88/393 (22%)

Query: 466  EKREDRTPYQLV--KKLQKKIRQFEEQFERERNS--KPSYSDIAANPKVLKWMTE----- 516
            E+ E+R  +     KK+Q+ I++ EEQ E E ++  K     +    K+ K   E     
Sbjct: 925  EEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILE 984

Query: 517  -----LTKLRKQIKD-------------------AKHKNSDGEFVPQTRPR--------- 543
                 L K +K ++D                   AK KN     +     R         
Sbjct: 985  DQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQ 1044

Query: 544  --SNTLPKSFGSSLDHEDEENEDEPKVIQ-KEKKPSKEATLELILKRLKEKRIERC---- 596
                T  K  G S D  D+  E + ++ + K +   KE  L+  L R++E+  ++     
Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK 1104

Query: 597  -----------LPEDI--------KVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSP 637
                       L ED+        K  K++R + + L      ++  L   +    L S 
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRS- 1163

Query: 638  STKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
              ++   +L+  +E E      +I+E  +       EL + L+   +V+++LE ++  +E
Sbjct: 1164 KREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLE 1223

Query: 698  ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKED 757
              + +LA ++++          LL+    +  ++KK+   L+E +  F +      +  D
Sbjct: 1224 NERGELANEVKV----------LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELAD 1273

Query: 758  RVPVLEEYREYKKIKAKLRLLEVLISKQDSSKS 790
            +V          K++ +L  +  L+S+ DS  S
Sbjct: 1274 KV---------TKLQVELDNVTGLLSQSDSKSS 1297



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 70/375 (18%), Positives = 147/375 (39%), Gaps = 51/375 (13%)

Query: 433  QSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFE 492
            Q +R L   ++     K     ++R      +DE+++        KKL+  ++  E   +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHID 1627

Query: 493  RERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSD-----GEFVPQTRPRSNTL 547
                        +AN    + + +L KL+ Q+KD   +  D      E + Q +     L
Sbjct: 1628 ------------SANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKL 1675

Query: 548  PKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL-----------ILKRLKEKRIERC 596
                  S++ E  + ++E    ++ K+ +++   EL            L   +++R+E  
Sbjct: 1676 -----KSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEAR 1730

Query: 597  LPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPIIEGETAH 656
            + +  +  +EE+   + + DR +     + + + T +    S  ++ +  +  +E +   
Sbjct: 1731 IAQLEEELEEEQGNTELINDRLKKANLQIDQIN-TDLNLERSHAQKNENARQQLERQNKE 1789

Query: 657  FFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQ---------EKLALDL 707
               ++K +E +G   S     +     ++    E  +++ +E Q         EK   D+
Sbjct: 1790 L--KVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDV 1847

Query: 708  RLS-SSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNG--RNAQK--EDRVPVL 762
             L       +  +  +Q  KA    K+L++ L E EE   + N   R  Q+  ED     
Sbjct: 1848 LLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETA 1907

Query: 763  EEY-REYKKIKAKLR 776
            +   RE   +K KLR
Sbjct: 1908 DAMNREVSSLKNKLR 1922



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 52/293 (17%), Positives = 113/293 (38%), Gaps = 29/293 (9%)

Query: 464  KDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQ 523
            ++E R+  +    +K+++ +   F EQ E E  +K +               ++  L  Q
Sbjct: 1318 QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK------------QIATLHAQ 1365

Query: 524  IKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL 583
            + D K K  D     +T   +  + +     L+   + +E++     K +K       EL
Sbjct: 1366 VADMKKKMEDSVGCLET---AEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQEL 1422

Query: 584  --ILKRLKEKRIERCLPEDIKVTKE----ERHIVKPLYDRYRLVKQMLTRASITPVLGSP 637
              +L  L  +R   C  E  +   +    E   +   Y   R   +   R   T  L   
Sbjct: 1423 DDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLA 1482

Query: 638  STKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
                     +  +E     F  E+++      ++   + ++ K+   ++  +E  ++ +E
Sbjct: 1483 RALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLE 1542

Query: 698  ENQE--------KLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFE 742
            E ++        KL L++ L + +A    +L  +  ++  +KK+L + +RE E
Sbjct: 1543 ELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREME 1595



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 63/338 (18%), Positives = 146/338 (43%), Gaps = 56/338 (16%)

Query: 478  KKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKNSDGEFV 537
            KK++ ++++ + +F      +   +D     KV K   EL  +   +             
Sbjct: 1248 KKVEAQLQELQVKFNEGERVRTELAD-----KVTKLQVELDNVTGLLS------------ 1290

Query: 538  PQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKRIERCL 597
             Q+  +S+ L K F +     + + +D  +++Q+E +  ++ +L   LK++++++     
Sbjct: 1291 -QSDSKSSKLTKDFSAL----ESQLQDTQELLQEENR--QKLSLSTKLKQVEDEK--NSF 1341

Query: 598  PEDIKVTKEERH-IVKPLYDRYRLVKQMLTRA--SITPVLGSPSTKRRGQMLQPIIEGET 654
             E ++  +E +H + K +   +  V  M  +   S+  +  +   KR+   LQ  +EG +
Sbjct: 1342 REQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRK---LQKDLEGLS 1398

Query: 655  AHFFEEIK---EEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE-------------- 697
                E++    + E+    L  EL D+L      + S  N E   +              
Sbjct: 1399 QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISA 1458

Query: 698  ---ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLR-EFEEAFYQQN--GR 751
               E +++   + R   ++A S+   LE+  + +AE ++L K  R E E+    ++  G+
Sbjct: 1459 KYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGK 1518

Query: 752  NAQKEDRVPVLEEYREYKKIKAKLRLLEVLISKQDSSK 789
            +  + ++     E ++ +++K +L  LE  +   + +K
Sbjct: 1519 SVHELEKSKRALE-QQVEEMKTQLEELEDELQATEDAK 1555



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 50/211 (23%), Positives = 87/211 (41%), Gaps = 26/211 (12%)

Query: 95   ENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEH-----IEELPEEGAEKSNDMPEVVQ- 148
            EN ++   S  L  + ++ N   E+ EE+E+ +H     I  L  + A+    M + V  
Sbjct: 1320 ENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGC 1379

Query: 149  LRMTENI---LESNSVTATSTHISPISILPASTDILERTIRAAVEQHLFDLQSSIDHDLK 205
            L   E +   L+ +    +  H   +    A+ D LE+T +  ++Q L DL   +DH   
Sbjct: 1380 LETAEEVKRKLQKDLEGLSQRHEEKV----AAYDKLEKT-KTRLQQELDDLLVDLDH--- 1431

Query: 206  NLQQQSVVCNNEAESIHCD---GEGSNNQIDIADDIINA-SESNRDCSKPVASTNLDNEA 261
               Q+   CN E +    D    E        A++   A +E+    +K ++      EA
Sbjct: 1432 ---QRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA 1488

Query: 262  MQQDCVFE--NEENTQSVGILLEPCSDRGDS 290
            M+Q    E  N++    +  L+    D G S
Sbjct: 1489 MEQKAELERLNKQFRTEMEDLMSSKDDVGKS 1519


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 76/361 (21%), Positives = 147/361 (40%), Gaps = 59/361 (16%)

Query: 439  HDPEKLDSSSKALSFTRIRRSSFSSK--DEKREDRTPYQLVKKLQKKIRQFEEQFERERN 496
            +D ++LD   K   F     S   SK  DE+       + +K+LQ +I + EE+ E ER 
Sbjct: 1075 NDKQQLDEKLKKKEF---EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERA 1131

Query: 497  SKPSYSDIAANPKVLKWMTELTKLRKQIKDA---------KHKNSDGEFVPQTR------ 541
            S+       A  +      EL ++ +++++A          +K  + EF    R      
Sbjct: 1132 SRAK-----AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEAT 1186

Query: 542  ----PRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLEL--------ILKRLK 589
                  + TL K    S+    E+ ++  +V QK +K   E  +E+         + + K
Sbjct: 1187 LQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAK 1246

Query: 590  E--KRIERCLPEDIK--VTKEERHIVKPLYDRYRLVKQMLT-RASITPVLGSPSTK--RR 642
               +++ R L + +    TKEE        ++ RL+  +   RA +    G  S +   +
Sbjct: 1247 GNLEKMCRALEDQLSEIKTKEE--------EQQRLINDLTAQRARLQTESGEYSRQLDEK 1298

Query: 643  GQMLQPIIEGETA--HFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQ 700
              ++  +  G+ A     EE+K + E+ +   S L   L+++      L     + +E +
Sbjct: 1299 DTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAK 1358

Query: 701  EKLALDLRLSSSRAASM-----PELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQK 755
             +L   +  ++S  A        + +++  +    KKKL + L++ EE     N + A  
Sbjct: 1359 AELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASL 1418

Query: 756  E 756
            E
Sbjct: 1419 E 1419



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 68/329 (20%), Positives = 144/329 (43%), Gaps = 46/329 (13%)

Query: 475  QLVK---KLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAKHKN 531
            QL+K   +L+ KI++  E+ E E       +++ A  + L+   E ++L+K I D +   
Sbjct: 911  QLIKTKIQLEAKIKEVTERAEDEEEIN---AELTAKKRKLE--DECSELKKDIDDLELTL 965

Query: 532  SDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILK-RLKE 590
            +  E       +     ++   +L  E    ++    + KEKK  +EA  + +   + +E
Sbjct: 966  AKVE-------KEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEE 1018

Query: 591  KRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQMLQPII 650
             ++       IK+ ++   +   L ++ + ++  L RA    + G     +   M    I
Sbjct: 1019 DKVNTLTKAKIKLEQQVDDLEGSL-EQEKKIRMDLERAK-RKLEGDLKLAQESTM---DI 1073

Query: 651  EGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLS 710
            E +     E++K++E +   L S++ D     +Q+Q  ++  ++ +EE +E++  + R S
Sbjct: 1074 ENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAE-RAS 1132

Query: 711  SSRA--------ASMPELLEQLWKA-----------RAEKKKLRKTLREFEEAFYQQNGR 751
             ++A          + E+ E+L +A           +  + + +K  R+ EEA  Q    
Sbjct: 1133 RAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEAT 1192

Query: 752  NA----QKEDRVPVL-EEYREYKKIKAKL 775
             A    +  D V  L E+    +++K KL
Sbjct: 1193 AATLRKKHADSVAELGEQIDNLQRVKQKL 1221



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 30/125 (24%), Positives = 57/125 (45%), Gaps = 10/125 (8%)

Query: 653  ETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSS 712
            + A   EE+K+E++   +L     ++ +T   +Q  L+ +E    +  +K    ++   +
Sbjct: 1765 DAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKK---QIQKLEA 1821

Query: 713  RAASMPELLEQLWKARAEK-KKLRKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKI 771
            R   +   +E   K   E  K LRK  R+ +E  YQ       +EDR  +L       K+
Sbjct: 1822 RVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQ------TEEDRKNILRLQDLVDKL 1875

Query: 772  KAKLR 776
            +AK++
Sbjct: 1876 QAKVK 1880


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 59/278 (21%), Positives = 113/278 (40%), Gaps = 24/278 (8%)

Query: 516 ELTKLRKQIKDAKHK-NSDGEFVPQTRPRSNTLPKSFGSSLDHEDEEN-EDEPKVIQKEK 573
           E+ KL KQ+ D   + N   + V + + +     +   S+    D++N + E   +Q E 
Sbjct: 424 EIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLAST--RRDQDNMQAELNRLQAEN 481

Query: 574 KPSKEATLELILKRLKEKRI--ERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASIT 631
             SKE   E +L+ L+E  +  ++   E    TKE   +   L  +   +  +       
Sbjct: 482 DASKEEVKE-VLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL 540

Query: 632 PVLGSPSTKRRGQM----LQPIIEGETAHFFEEIKEEEEDGV-------------NLSSE 674
             + +   KR  +M    L+ + E   A    ++K+ E  G+              + SE
Sbjct: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600

Query: 675 LGDMLKTAVQVQSSLENSESDVEENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKL 734
           +  M+K   Q++S+   S   +EEN+++LA      S   A +  L E L     +K++L
Sbjct: 601 VKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQL 660

Query: 735 RKTLREFEEAFYQQNGRNAQKEDRVPVLEEYREYKKIK 772
            +++    E   Q   +    E     L + +   ++K
Sbjct: 661 EESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVK 698


>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
          Length = 1790

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 61/249 (24%), Positives = 106/249 (42%), Gaps = 45/249 (18%)

Query: 537  VPQTRPRSNTLP----KSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRLKEKR 592
            +PQ   R   LP    + +G  +   +EE E+E +  +K KKP  E         ++E  
Sbjct: 1473 MPQYGSRRRLLPPAGQEEYGEVVGEAEEEYEEEEEEPKKIKKPKVE---------IREPS 1523

Query: 593  IERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRRGQM-LQPIIE 651
             E    E++ VT E+    +P Y  ++       RA I P++     K RG    + I++
Sbjct: 1524 EE----EEVVVTIEKPPAAEPTYTTWK-------RARIFPMI---FKKVRGLADKRGIVD 1569

Query: 652  GETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQ---------VQSSLENSESDVEENQEK 702
             E   +   ++EE++D + L+ +  +  ++ V+          + S E SE    E  E+
Sbjct: 1570 LEGEEWQRRLEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYSEEESEFSESETTEE 1629

Query: 703  LALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTL-----REFEEAFYQQNGR--NAQK 755
             +     S    +S PE  E+     +E +K RK +     R   E   +  GR    Q+
Sbjct: 1630 ESESETPSEEEESSTPE-SEESESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQE 1688

Query: 756  EDRVPVLEE 764
            E + P +EE
Sbjct: 1689 EQKEPKMEE 1697



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 4/58 (6%)

Query: 97   EEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTEN 154
            E E+ SS+D +  +E+ +E SE E  +E+ E   E P E  E S   PE  +   TE+
Sbjct: 1602 ESEEESSSDYTEYSEEESEFSESETTEEESE--SETPSEEEESST--PESEESESTES 1655


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 141/742 (19%), Positives = 284/742 (38%), Gaps = 92/742 (12%)

Query: 62   DVFHIYTDVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEE 121
            DV  +   +E+  +Q  V+ I   + E   +   NEE+     ++ ++ EQ+N LS  EE
Sbjct: 888  DVETLQQTIEEKDQQ--VTEISFSMTEKMVQL--NEEKFSLGVEIKTLKEQLNLLSRAEE 943

Query: 122  -EDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDI 180
             + E++E   E+     +  ++M    Q+   E   E               +L    + 
Sbjct: 944  AKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHE-------------FDLLKKENEQ 990

Query: 181  LERTIRAAV--EQHLFDLQSSIDHDLKNLQQQSVVCNNEAESIHCDGEGSNNQIDIAD-- 236
             +R ++AA+   + L    S ++ +L NL+ +S                   +I +++  
Sbjct: 991  RKRKLQAALINRKELLQRVSRLEEELANLKDES-----------------KKEIPLSETE 1033

Query: 237  --DIINASESNRDCSKPVASTNLDNEAMQQDCVFENEENTQSVGILLEPCSDRGDSEDGC 294
              ++    E+     K V S   + E   +  + E E   Q +   LE      +     
Sbjct: 1034 RGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL 1093

Query: 295  LEREEYLLFDSDKLSHLI---LDSSSKICDLNANTESEVPGGQSVGVQGEAACVSIPHLD 351
            +++    L D      L+   +  +  I      + ++   G SV +  E   +S P   
Sbjct: 1094 VKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPC-- 1151

Query: 352  LKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSESGEAQLSPQAGRM 411
                   + W+       P ++ K + L+++ E+     K  QE   S +A L  +A   
Sbjct: 1152 ---TGSSEHWK-------PELEEKILALEKEKEQ---LQKKLQEALTSRKAILK-KAQEK 1197

Query: 412  NHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEK----LDSSSKALSFTRIRRS---SFSSK 464
              H  EE     L  +  D+ + Q    +  K    +    + L   ++R S      S 
Sbjct: 1198 ERHLREE-----LKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQI-QVRESIDGKLPST 1251

Query: 465  DEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQI 524
            D++    +   L + L K   Q   Q   E N  P +   + +   L+  T + +++ Q+
Sbjct: 1252 DQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTSVAQIKAQL 1311

Query: 525  KDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATL--E 582
            K+ + +  + E   +    ++ L K        +++ N+   + I+  K  S EA +  E
Sbjct: 1312 KEIEAEKVELEL--KVSSTTSELTKKSEEVFQLQEQINKQGLE-IESLKTVSHEAEVHAE 1368

Query: 583  LILKRLKEKRIERCLPEDI-----KVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSP 637
             + ++L+  +++    E +     K+ + ++ I K   D   L  Q+  + +    + + 
Sbjct: 1369 SLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTE 1428

Query: 638  STKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVE 697
              ++     + +I+        + KE +E    L  EL +M +   ++    E S +  +
Sbjct: 1429 IIEQ-----EDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIG---EESRAK-Q 1479

Query: 698  ENQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKED 757
            + Q KL   L            L E+L  AR   ++L K+L + E     QN        
Sbjct: 1480 QIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLG 1539

Query: 758  RVPVLEEYREYKKIKAKLRLLE 779
            R+ +L+E R+    +    LLE
Sbjct: 1540 RLALLQEERDKLITEMDRSLLE 1561



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 136/752 (18%), Positives = 287/752 (38%), Gaps = 121/752 (16%)

Query: 71   EDMKEQEIVSRIMAGLLENYYEFFENE--EEDFS---------SNDLSSITEQVNELSEE 119
            E   +Q+I  ++ A L+       EN+  +E+ S         +  L+ +  QV+  ++ 
Sbjct: 1474 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVS--AQN 1531

Query: 120  EEEDEKLEHIEELPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTD 179
            +E+D  L  +  L EE  +   +M          ++LE+ S++++   +     L   T+
Sbjct: 1532 KEKDTVLGRLALLQEERDKLITEMDR--------SLLENQSLSSSCESLK--LALEGLTE 1581

Query: 180  ILERTIRAAVEQHLFDLQSSIDHDLKNLQQQSVV---------CNNEAESIHCDGEGSNN 230
              E+ ++         +  S +   K+ + Q             +NEAE I    E    
Sbjct: 1582 DKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQ 1641

Query: 231  QIDIADDIINASESNR-DCSKPVASTNLDNEAMQ----------QDCVFENEENTQSVGI 279
            +       + ++E+N+ +  K +     + E M+          Q  + E EE    +  
Sbjct: 1642 EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRA 1701

Query: 280  LLEPCSDRGDSEDGCLEREEYLLFDSDKLSHLILDSSSKICDLN-ANTESEVPGGQSVGV 338
             + P    GD+   C+E              L+  ++S   +L     E E    +   +
Sbjct: 1702 EVHPA---GDTAKECMET-------------LLSSNASMKEELERVKMEYETLSKKFQSL 1745

Query: 339  QGEAACVSIPHLDLKNVSDGDKWEASCPITFPLIDFKTMHLQRDGEEPFPAFKSWQEDSE 398
              E   +S    DLK+  +G+  + +        D +T ++  +G +  P      E  E
Sbjct: 1746 MSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQT-NVTEEGTQSIPG-----ETEE 1799

Query: 399  SGEAQLSPQAGRMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRR 458
                 +S +       P  +   P +S       +   +L   ++L      L   + + 
Sbjct: 1800 QDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKN 1859

Query: 459  SSFSSKDEKREDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELT 518
              FS   E  ++    Q+  K   +++  +E+  +             N ++ + ++ +T
Sbjct: 1860 KEFSQTLENEKNTLLSQISTK-DGELKMLQEEVTKMN---------LLNQQIQEELSRVT 1909

Query: 519  KLRKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPK--VIQKEKKPS 576
            KL++  ++ K    +           N L +  GS  ++  +  + + K  +++ E K  
Sbjct: 1910 KLKETAEEEKDDLEERLM--------NQLAELNGSIGNYCQDVTDAQIKNELLESEMKNL 1961

Query: 577  KEATLELILKRLKEKRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGS 636
            K+   EL      E+  ++ + E  KV  E R             K+ L +  I      
Sbjct: 1962 KKCVSEL------EEEKQQLVKEKTKVESEIR-------------KEYLEK--IQGAQKE 2000

Query: 637  PSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDV 696
            P  K   + LQ +++ +     +E+K+ ++D +    ++  + +T   ++     S+ D+
Sbjct: 2001 PGNKSHAKELQELLKEKQ----QEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL 2056

Query: 697  EENQEKLALDL---RLSSSRAASMPELLE----QLWKARAEKKKLRKTLREFEEAFYQQN 749
            E  +E LA  +   + + +  AS   LL+    +  +  A+  KL+K L+  +E+   Q 
Sbjct: 2057 EITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQ- 2115

Query: 750  GRNAQKEDRVPVLEEYREYKKIKAKLRLLEVL 781
                QK++ +    E  E K +K K  + E L
Sbjct: 2116 --MKQKDEDLERRLEQAEEKHLKEKKNMQEKL 2145



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 63/325 (19%), Positives = 127/325 (39%), Gaps = 53/325 (16%)

Query: 469  EDRTPYQLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKLRKQIKDAK 528
            E R   Q+ +KLQ  +   +E  +  ++ +   S              + +L K + D +
Sbjct: 1474 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGT---------IERLTKSLADVE 1524

Query: 529  HKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEATLELILKRL 588
             + S      Q + +   L +      + +    E +  +++ +   S   +L+L L+ L
Sbjct: 1525 SQVS-----AQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGL 1579

Query: 589  KE------KRIERCLPEDIKVTKEERHIVKPLYDRYRLVKQMLTRASITPVLGSPSTKRR 642
             E      K IE      I  + E +   K L   Y ++ Q     S             
Sbjct: 1580 TEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVS-----------NE 1628

Query: 643  GQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENSESDVEENQEK 702
             + +Q        H  E +++E+++   L  +L        + +  L+ +E ++EE +EK
Sbjct: 1629 AERIQ--------HVVEAVRQEKQE---LYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677

Query: 703  LALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGRNAQKEDRVPVL 762
            +    + + S+   + EL E+  + RAE      T +E  E     N    ++ +RV + 
Sbjct: 1678 MR---KFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKM- 1733

Query: 763  EEYREYKKIKAKLRLLEVLISKQDS 787
                EY+ +  K    + L+S++DS
Sbjct: 1734 ----EYETLSKK---FQSLMSEKDS 1751



 Score = 37.0 bits (84), Expect = 0.071
 Identities = 79/368 (21%), Positives = 152/368 (41%), Gaps = 31/368 (8%)

Query: 410  RMNHHPLEEDCPPVLSHRSLDFGQSQRFLHDPEKLDSSSKALSFTRIRRSSFSSKDE--- 466
            ++N   LE +    +SH +    +S +     +KL+SS   ++     R      DE   
Sbjct: 1345 QINKQGLEIESLKTVSHEAEVHAESLQ-----QKLESSQLQIAGLEHLRELQPKLDELQK 1399

Query: 467  ---KREDRTPY---QLVKKLQKKIRQFEEQFERERNSKPSYSDIAANPKVLKWMTELTKL 520
               K+E+   Y   QL +K     +   E  E+E   K  ++ +    K  +    + +L
Sbjct: 1400 LISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAK--EHDERIKQL 1457

Query: 521  RKQIKDAKHKNSDGEFVPQTRPRSNTLPKSFGSSLDHEDEENEDEPKVIQKEKKPSKEAT 580
            + ++ + K K    E   ++R +     K   + +  ++   E+  K +Q+E   ++  T
Sbjct: 1458 QVELCEMKQKPE--EIGEESRAKQQIQRKLQAALISRKEALKEN--KSLQEELSLAR-GT 1512

Query: 581  LELILKRLKEKRIERCLPEDIKVT--------KEERHIVKPLYDRYRLVKQMLTRASITP 632
            +E + K L +   +       K T        +EER  +    DR  L  Q L+ +  + 
Sbjct: 1513 IERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESL 1572

Query: 633  VLGSPSTKRRGQMLQPIIEGETAHFFEEIKEEEEDGVNLSSELGDMLKTAVQVQSSLENS 692
             L         + L   IE   +    E  E +E    L  E   +L++   V +  E  
Sbjct: 1573 KLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERI 1632

Query: 693  ESDVEE-NQEKLALDLRLSSSRAASMPELLEQLWKARAEKKKLRKTLREFEEAFYQQNGR 751
            +  VE   QEK  L  +L S+ A +  E  +QL +A  E +++++ +R+F ++  Q+   
Sbjct: 1633 QHVVEAVRQEKQELYGKLRSTEA-NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILE 1691

Query: 752  NAQKEDRV 759
              ++ DR+
Sbjct: 1692 LEEENDRL 1699



 Score = 35.8 bits (81), Expect = 0.16
 Identities = 39/146 (26%), Positives = 65/146 (44%), Gaps = 16/146 (10%)

Query: 72   DMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEHIEE 131
            +MKEQ+I+S     LL    E  +    +        I E  N LS+EEEE+  LE   E
Sbjct: 2378 NMKEQKIIS-----LLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLE---E 2429

Query: 132  LPEEGAEKSNDMPEVVQLRMTENILESNSVTATSTHISPISILPASTDILERTIRAAVEQ 191
              ++  +K+N + E ++    ENI +   +    + +  +S L    D +    +   E+
Sbjct: 2430 ENKKAVDKTNQLMETLKTIKKENIQQKAQL---DSFVKSMSSLQNDRDRIVGDYQQLEER 2486

Query: 192  HLFDLQSSIDHDLKNLQQQSVVCNNE 217
            HL     SI  +   L Q++   NN+
Sbjct: 2487 HL-----SIILEKDQLIQEAAAENNK 2507



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 41/142 (28%), Positives = 71/142 (50%), Gaps = 19/142 (13%)

Query: 650 IEGETAHFFEEIKEEEEDGVNLS-SELGDMLKTAVQVQSSLENSESDVEENQEKLALDLR 708
           IE ++     E+ + E D V L  SE   ++++   +QS L+N ES+V E  E++     
Sbjct: 803 IEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRS---LQSQLQNKESEVLEGAERVR---H 856

Query: 709 LSS-----SRAASMPEL-LEQLWKARAEKKKLRKTLRE-FEEAFYQQNGRNAQKEDRVPV 761
           +SS     S+A S  EL + ++ +   EKK+  +TL++  EE   Q    +    +++  
Sbjct: 857 ISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQ 916

Query: 762 LEEYR-----EYKKIKAKLRLL 778
           L E +     E K +K +L LL
Sbjct: 917 LNEEKFSLGVEIKTLKEQLNLL 938



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 39/164 (23%), Positives = 66/164 (40%), Gaps = 25/164 (15%)

Query: 69   DVEDMKEQEIVSRIMAGLLENYYEFFENEEEDFSSNDLSSITEQVNELSEEEEEDEKLEH 128
            ++  +KEQ +++R    LL     F  N  E+ S + L  + +Q+        +DE+L H
Sbjct: 2767 ELAQLKEQGLLNRERDALLSET-AFSMNSTEENSLSHLEKLNQQLLS------KDEQLLH 2819

Query: 129  IEELPEEGAEKSNDMPEVVQLRMTE-----NILES--NSVTATSTHISPISILPASTDIL 181
            +    E+   +     + +     E     N LE    S        +  S  PA    L
Sbjct: 2820 LSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSL 2879

Query: 182  ERTIRAAVEQHLFDLQSSIDH---DLKNLQQQSVVCNNEAESIH 222
            ++ + +        LQ+  D    +LKNLQQQ +  N E   +H
Sbjct: 2880 KKAMSS--------LQNDRDRLLKELKNLQQQYLQINQEITELH 2915


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,529,093
Number of Sequences: 37866
Number of extensions: 1492826
Number of successful extensions: 11130
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 113
Number of HSP's successfully gapped in prelim test: 551
Number of HSP's that attempted gapping in prelim test: 8259
Number of HSP's gapped (non-prelim): 2614
length of query: 791
length of database: 18,247,518
effective HSP length: 110
effective length of query: 681
effective length of database: 14,082,258
effective search space: 9590017698
effective search space used: 9590017698
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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