Guide to the Human Genome
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Search of human proteins with 154937380

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154937380 hypothetical protein LOC642475 [Homo sapiens]
         (719 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154937380 hypothetical protein LOC642475 [Homo sapiens]           1436   0.0  
gi|223278410 hypothetical protein LOC374977 [Homo sapiens]            184   2e-46
gi|148727311 hypothetical protein LOC389690 [Homo sapiens]            159   7e-39
gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapi...   157   4e-38
gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5...   150   4e-36
gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]       150   4e-36
gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     122   1e-27
gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     121   2e-27
gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     116   6e-26
gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]              86   1e-16
gi|117956387 hypothetical protein LOC80133 [Homo sapiens]              41   0.003
gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo sapi...    39   0.017
gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo sapi...    39   0.017
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    38   0.029
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    38   0.029
gi|4503121 cardiotrophin 1 isoform 1 [Homo sapiens]                    38   0.037
gi|169171388 PREDICTED: hypothetical protein [Homo sapiens]            37   0.049
gi|239749096 PREDICTED: hypothetical protein [Homo sapiens]            37   0.049
gi|239743123 PREDICTED: hypothetical protein [Homo sapiens]            37   0.049
gi|12751477 forkhead box L2 [Homo sapiens]                             37   0.083
gi|156416026 zinc finger protein 219 [Homo sapiens]                    37   0.083
gi|156415998 zinc finger protein 219 [Homo sapiens]                    37   0.083
gi|156415996 zinc finger protein 219 [Homo sapiens]                    37   0.083
gi|4503969 growth differentiation factor 5 preproprotein [Homo s...    36   0.11 
gi|216548056 cardiotrophin 1 isoform 2 [Homo sapiens]                  36   0.11 
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    36   0.11 
gi|224451082 cytospin A [Homo sapiens]                                 35   0.19 
gi|224451080 cytospin A [Homo sapiens]                                 35   0.19 
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    35   0.19 
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    35   0.19 

>gi|154937380 hypothetical protein LOC642475 [Homo sapiens]
          Length = 719

 Score = 1436 bits (3716), Expect = 0.0
 Identities = 719/719 (100%), Positives = 719/719 (100%)

Query: 1   MAGGVWGRSRAREAPVGALTLTALTEGIRARQGQPQGPPSAGPQPKSWEVKPEAEPQTQA 60
           MAGGVWGRSRAREAPVGALTLTALTEGIRARQGQPQGPPSAGPQPKSWEVKPEAEPQTQA
Sbjct: 1   MAGGVWGRSRAREAPVGALTLTALTEGIRARQGQPQGPPSAGPQPKSWEVKPEAEPQTQA 60

Query: 61  LTAPSEAEPGRGATVPEAGSEPCSLNSALEPAPEGPHQVPQSSWEEGVLADLALYTAACL 120
           LTAPSEAEPGRGATVPEAGSEPCSLNSALEPAPEGPHQVPQSSWEEGVLADLALYTAACL
Sbjct: 61  LTAPSEAEPGRGATVPEAGSEPCSLNSALEPAPEGPHQVPQSSWEEGVLADLALYTAACL 120

Query: 121 EEAGFAGTQATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSAL 180
           EEAGFAGTQATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSAL
Sbjct: 121 EEAGFAGTQATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSAL 180

Query: 181 ALEHARDVVCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQALA 240
           ALEHARDVVCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQALA
Sbjct: 181 ALEHARDVVCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQALA 240

Query: 241 ATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLARSPCSPDMPKIWVLSHRGPPHSH 300
           ATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLARSPCSPDMPKIWVLSHRGPPHSH
Sbjct: 241 ATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLARSPCSPDMPKIWVLSHRGPPHSH 300

Query: 301 ASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMVAHADHHLRG 360
           ASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMVAHADHHLRG
Sbjct: 301 ASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMVAHADHHLRG 360

Query: 361 LFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILERLLTWQGDPEPTVRWL 420
           LFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILERLLTWQGDPEPTVRWL
Sbjct: 361 LFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILERLLTWQGDPEPTVRWL 420

Query: 421 GLLGLGHLALNRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLLSA 480
           GLLGLGHLALNRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLLSA
Sbjct: 421 GLLGLGHLALNRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLLSA 480

Query: 481 ELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRGPLRKLVLQSLVPLLLRLH 540
           ELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRGPLRKLVLQSLVPLLLRLH
Sbjct: 481 ELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRGPLRKLVLQSLVPLLLRLH 540

Query: 541 DPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFL 600
           DPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFL
Sbjct: 541 DPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFL 600

Query: 601 SQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAA 660
           SQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAA
Sbjct: 601 SQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAA 660

Query: 661 AHVSAQQVAMLARARGCPRGPRLLRIAPRPARPPPVFADSPFQRRSVAGRWGCSGPRRA 719
           AHVSAQQVAMLARARGCPRGPRLLRIAPRPARPPPVFADSPFQRRSVAGRWGCSGPRRA
Sbjct: 661 AHVSAQQVAMLARARGCPRGPRLLRIAPRPARPPPVFADSPFQRRSVAGRWGCSGPRRA 719


>gi|223278410 hypothetical protein LOC374977 [Homo sapiens]
          Length = 1323

 Score =  184 bits (468), Expect = 2e-46
 Identities = 180/610 (29%), Positives = 278/610 (45%), Gaps = 37/610 (6%)

Query: 130  ATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSALALEHARDVV 189
            A+ + LSS LE    R  + +  +++G+  Q+  + E R  + AL  +S LA     +VV
Sbjct: 723  ASEVMLSSVLEWYRHRALEVIPEIMQGIYMQLSHIQEPRARQVALLPVSLLASSFMTEVV 782

Query: 190  CALLPRSLPADRVAAELWRSL-----SRNQRVNGQVLVQLLWALK-------GASGPEPQ 237
             ALL   LP +   AE+WR L     S + R    +L  LL +LK       G +   P 
Sbjct: 783  VALLMCPLPLNSNGAEMWRQLILCKPSCDVR---DLLDLLLGSLKEKPVTKEGRASIVP- 838

Query: 238  ALAATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLA--RSPCSPDMPKIWVLSHRG 295
             LAA   L E+L+V+ C+G  R  YP LLLAL+ Q+H       P     PK      + 
Sbjct: 839  -LAAASGLCELLSVNSCMGRVRRIYPQLLLALLIQVHYHIGLNLPGCVAPPKDTKKGAQP 897

Query: 296  PPHSHASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMVAHAD 355
             P       V+ +K LL   G     T +E  GGW  +    +H  GV LLA AMV ++ 
Sbjct: 898  SPFVPVRWVVKVVKTLLLRMGCSYETTFLEDQGGWELMEQVESHHRGVALLARAMVQYSC 957

Query: 356  HHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILERLLTWQGDPEP 415
              L  +   L+P L   D+  R+TA AFF  LLQ     R + EE  L R+       +P
Sbjct: 958  QELCRILYLLIPLLERGDEKHRITATAFFVELLQMEQVRR-IPEEYSLGRMAEGLSHHDP 1016

Query: 416  TVRWLGLLGLGHLALNRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPV 475
             ++ L + GL  LA    K   V  LLP+++  L   D  LV  A+  L + + + R   
Sbjct: 1017 IMKVLSIRGLVILARRSEKTAKVKALLPSMVKGLKNMDGMLVVEAVHNL-KAVFKGRDQK 1075

Query: 476  RLLSA---ELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRGPLRKLVLQSL 532
             + SA   E+   L P   D R+ +R+S + L G +V++    LR      + + ++ +L
Sbjct: 1076 LMDSAVYVEMLQILLPHFSDAREVVRSSCINLYGKVVQK----LRAPRTQAMEEQLVSTL 1131

Query: 533  VPLLLRLHDPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDS-PEALSHLCCRLVQR 591
            VPLLL + + +   ++    TL RC +   W L +   +   +D+  + ++ +C  LV  
Sbjct: 1132 VPLLLTMQEGNSKVSQKCVKTLLRCSYFMAWELPKRAYSRKPWDNQQQTVAKICKCLVNT 1191

Query: 592  YPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDLLDSLFQDLGRLQS 651
            +      FLSQ+  Y ++ +  LR+ + + IG LV       + +D L+ +   L  L+ 
Sbjct: 1192 HRDSAFIFLSQSLEYAKNSRASLRKCSVMFIGSLV-PCMESIMTEDRLNEVKAALDNLRH 1250

Query: 652  DPKPAVAA-AAHVSAQQVAMLARARGCPRGPRLLRIAPRPARPPPVFADSP--FQRRS-- 706
            DP+ +V   AA V    +A   +    P G   +  +    R  P   + P   QRRS  
Sbjct: 1251 DPEASVCIYAAQVQDHILASCWQNSWLPHGNSWVCYSATTHRWSPSCENLPTSHQRRSWI 1310

Query: 707  --VAGRWGCS 714
                G W  S
Sbjct: 1311 MQALGSWKMS 1320


>gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
          Length = 1318

 Score =  159 bits (403), Expect = 7e-39
 Identities = 172/609 (28%), Positives = 259/609 (42%), Gaps = 39/609 (6%)

Query: 98   QVPQSSWEEGVLADLALYTAACLEEAGFAG---TQATVLTLSSALEARGERLEDQVHALV 154
            QV +   ++  LA+L+      ++  G       QA    L +A++  G +LE  V ++ 
Sbjct: 721  QVIKDIMQQLTLAELSDLIWTAIDGLGSTSPFRVQAASEMLLTAVQEHGAKLEI-VSSMA 779

Query: 155  RGLLAQVPSLAEGRPWRAALRVLSALALEHARDVVCALLPRSLPADRVAAELWRSLSRNQ 214
            + +  ++ S+   +     L  ++ LA  H  ++V   L  S+P D    +LWR+L   Q
Sbjct: 780  QAIRLRLCSVHIPQAKEKTLHAITLLARSHTCELVATFLNISIPLDSHTFQLWRALGAGQ 839

Query: 215  RVNGQVLVQLLWALK------GASGPEP--------QALAATRALGEMLAVSGCVGATRG 260
              +  VL  LL  L+      GAS   P        + LAA   L E+        A + 
Sbjct: 840  PTSHLVLTTLLACLQERPLPTGASDSSPCPKEKTYLRLLAAMNMLHELQFAREFKQAVQE 899

Query: 261  FYPHLLLALVTQLHKLARS--PCSPDMPKIWVLSHRGPPHSHASCAVEALKALLTGDGGR 318
             YP L LAL+TQ+H +     P  P  PK        P     S ++EALK+LL+  G  
Sbjct: 900  GYPKLFLALLTQMHYVLELNLPSEPQ-PKQQAQEAAVPSPQSCSTSLEALKSLLSTTGHW 958

Query: 319  MVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMVAHADHHLRGLFADLLPRLRSADDPQRL 378
                 +E  G W      HT+ +GV LLA AMV +    +  +   LLP L+S  + +R 
Sbjct: 959  HDFAHLELQGSWELFTTIHTYPKGVGLLARAMVQNHCRQIPAVLRQLLPSLQSPQERERK 1018

Query: 379  TAMAFFTGLLQSRPTARLLREEVILERLLTWQGDPEPTVRWLGLLGLGHLALNRRKVRHV 438
             A+   T  L S     +L ++  L  L     DP P VR L L GL ++  +  K   +
Sbjct: 1019 VAILILTKFLYSPVLLEVLPKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFHPDKGSLL 1078

Query: 439  STLLPALLGALGEGDARLVGAALGALRRLLLRPRAP---VRLLSAELGPRLPPLLDDTRD 495
               L  LL    +   +++   +G +   L R  A     + L   +  R     +D RD
Sbjct: 1079 QGQLRPLLDGFFQSSDQVIVCIMGTVSDTLHRLGAQGTGSQSLGVAISTR--SFFNDERD 1136

Query: 496  SIRASAVGLLGTLVRRGRGGLRLGLRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLA 555
             IRA+A+ L G LV         G    LR  V QS+VPLLL L D     A  +++T  
Sbjct: 1137 GIRAAAMALFGDLVAAMADRELSG----LRTQVHQSMVPLLLHLKDQCPAVATQAKFTFY 1192

Query: 556  RCDHAFCWGLLEEL-VTVAHYDSPEALSHLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPL 614
            RC     W LL  L  T+A      A   L   L+ R        LSQ   YL S    +
Sbjct: 1193 RCAVLLRWRLLHTLFCTLAWERGLSARHFLWTCLMTRSQEEFSIHLSQALSYLHSHSCHI 1252

Query: 615  RRAAAVLIGFLVHHASPGCVNQDL----LDSLFQDLGRLQSDPKPAVAAAAHVSAQQVAM 670
            +    + IG  + +  P  V Q L     + LF+    L+SDP+P++   A     Q++ 
Sbjct: 1253 KTWVTLFIGHTICY-HPQAVFQMLNAVDTNLLFRTFEHLRSDPEPSIREFA---TSQLSF 1308

Query: 671  LARARGCPR 679
            L +    P+
Sbjct: 1309 LQKVSARPK 1317


>gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapiens]
          Length = 1052

 Score =  157 bits (396), Expect = 4e-38
 Identities = 150/558 (26%), Positives = 253/558 (45%), Gaps = 25/558 (4%)

Query: 132  VLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSA-LALEHARDVVC 190
            +LTL+   E++ E++ +    ++  + AQ+  +++ R  +  +  +S  ++     D+V 
Sbjct: 493  LLTLAKNTESQFEKVPE----IMGVICAQLSIISQPRVRQQIINTVSLFISRPKYTDIVL 548

Query: 191  A-LLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQ------ALAATR 243
            + LL   +P +R  AE+WR LS        +L +LL  L+       Q      A+AAT 
Sbjct: 549  SFLLCHPVPYNRHLAEVWRMLSVELPSTTWILWRLLRKLQKCHNEPAQEKMAYVAVAATD 608

Query: 244  ALGEMLAVSGCVGATRGFYPHLLLALVTQLH-KLARSPCSPDMPKIWVLSHRGPPHSHAS 302
            AL E+   +    AT   +P LL+ L+ Q+H  +  +    D+P         P      
Sbjct: 609  ALYEVFLGNRLRAATFRLFPQLLMTLLIQIHHSIGLTMSDVDIPSGLYTEQEVPSEVTPL 668

Query: 303  C-AVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMVAHADHHLRGL 361
            C A++A K LL           ME+  GW  L G   HL+G+ LLA+A++       + +
Sbjct: 669  CFAMQATKTLLLRTCCLQEFNIMEKNKGWALLGGKDGHLQGLFLLANALLERNQLLAQKV 728

Query: 362  FADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILERLLTWQGDPEPTVRWLG 421
               L+P L   +D  +LT+  FF  LL+S P A+ L     + R   W  D     R LG
Sbjct: 729  MYLLVPLLNRGNDKHKLTSAGFFVELLRS-PVAKRLPSIYSVARFKDWLQDGNHLFRILG 787

Query: 422  LLGLGHLALNRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLLSAE 481
            L GL +L  ++     + +LLP ++ +L E D ++V   L A++ LL   R       A 
Sbjct: 788  LRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIV---LSAIQILLQLVRTMDFTTLAA 844

Query: 482  LGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRGPLRKLVLQSLVPLLLRLHD 541
            +   L  L  D R  +   +V L G  ++  +   +  +       VL SLVPLLL   D
Sbjct: 845  MMRTLFSLFGDVRSDVHRFSVTLFGAAIKSVKNPDKKSIENQ----VLDSLVPLLLYSQD 900

Query: 542  PSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFLS 601
             +   AE S   L  C     W L +E+ +   +      +   CR  ++      N L 
Sbjct: 901  ENDAVAEESRQVLTICAQFLKWKLPQEVYSKDPWHIKPTEAGTICRFFEKKCKGKINILE 960

Query: 602  QTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAAA 661
            QT  Y ++P+ P+RR+A + +G L  +     + +   D +  DL  L  DP+P++    
Sbjct: 961  QTLMYSKNPKLPIRRSAVLFVGLLSKYMDHNELRRMGTDWIEDDLRDLLCDPEPSLCI-- 1018

Query: 662  HVSAQQVAMLARARGCPR 679
             +++Q + ++  AR  P+
Sbjct: 1019 -IASQTLLLVQMARAEPK 1035


>gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5
            [Homo sapiens]
          Length = 1218

 Score =  150 bits (379), Expect = 4e-36
 Identities = 170/586 (29%), Positives = 246/586 (41%), Gaps = 55/586 (9%)

Query: 128  TQATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSALALEHARD 187
            ++A  + ++  L+ RG  L+++V  +V  L +++          AA   +  LA +H   
Sbjct: 647  SRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAA 706

Query: 188  VVCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWAL-KGASGPEPQA-------- 238
            VV +LL   LP D     LWR+L+   R+  QVL  LL  + +     E +A        
Sbjct: 707  VVSSLLGSPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKMSRDVPFKESRAFLLGRTPD 766

Query: 239  -------LAATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLARSPCSP--DMPK-I 288
                   L+AT AL E+++      A    YP L + L      L R  C+    +P+ +
Sbjct: 767  RVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVVL------LLRVSCTVGVQLPRNL 820

Query: 289  WVLSHRGPPHSHA-------SCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLE 341
                 RG   + A       S AV+ L+++L   G   VV  M+  GGW  L  +  H E
Sbjct: 821  QAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEE 880

Query: 342  GVLLLASAMVAHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEV 401
            G   LA AM  HA   L  +   L     SA + QR+T  AF   LL S     L+  + 
Sbjct: 881  GATRLARAMAEHAGPRLPLVLKTLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDS 940

Query: 402  ILERLLTWQGDPEPTVRWLGLLGLGHLALN-RRKVR-HVSTLLPALLGALGEGD----AR 455
            +LE L   Q D   +VR L L GL +LA     KVR H   LL A++G L +GD      
Sbjct: 941  LLESLAARQKDTCASVRRLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPV 1000

Query: 456  LVGAALGALRRLLLRPRAPVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGG 515
             + A LG  R + L     +R     +  R+ P  D  +   R +++ L G L +   G 
Sbjct: 1001 ALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHG- 1059

Query: 516  LRLGLRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARC---------DHAFCWGLL 566
                        V+  L PLLL L DP    A +  + L  C           AF   L 
Sbjct: 1060 ---DCEDVFLDQVVGGLAPLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQ 1116

Query: 567  EELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGFLV 626
            E      H+   E L+  C  L+  +P  +   L+    Y +S  + +R AA +  GFLV
Sbjct: 1117 EG--RALHFG--EFLNTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAAAPLFTGFLV 1172

Query: 627  HHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAAAHVSAQQVAMLA 672
             H+ P    Q  LD L   L  L  DP P V   A  +  ++  LA
Sbjct: 1173 LHSEPRQQPQVDLDQLIAALQILLKDPAPEVRTRAAEALGRLVKLA 1218


>gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]
          Length = 1641

 Score =  150 bits (379), Expect = 4e-36
 Identities = 170/586 (29%), Positives = 246/586 (41%), Gaps = 55/586 (9%)

Query: 128  TQATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSALALEHARD 187
            ++A  + ++  L+ RG  L+++V  +V  L +++          AA   +  LA +H   
Sbjct: 1070 SRAATVMINCLLQERGGVLQEKVPEIVSVLRSKLQEAQGEHVLPAAQHSVYLLATQHCAA 1129

Query: 188  VVCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWAL-KGASGPEPQA-------- 238
            VV +LL   LP D     LWR+L+   R+  QVL  LL  + +     E +A        
Sbjct: 1130 VVSSLLGSPLPLDSHTCMLWRALAVEPRLAAQVLGLLLEKMSRDVPFKESRAFLLGRTPD 1189

Query: 239  -------LAATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLARSPCSP--DMPK-I 288
                   L+AT AL E+++      A    YP L + L      L R  C+    +P+ +
Sbjct: 1190 RVATLLPLSATCALFEVMSTPAAGPAVLELYPQLFVVL------LLRVSCTVGVQLPRNL 1243

Query: 289  WVLSHRGPPHSHA-------SCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLE 341
                 RG   + A       S AV+ L+++L   G   VV  M+  GGW  L  +  H E
Sbjct: 1244 QAQERRGASPALATRNLEPCSSAVDTLRSMLLRSGSEDVVQRMDLEGGWELLRTSAGHEE 1303

Query: 342  GVLLLASAMVAHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEV 401
            G   LA AM  HA   L  +   L     SA + QR+T  AF   LL S     L+  + 
Sbjct: 1304 GATRLARAMAEHAGPRLPLVLKTLACTHSSAYENQRVTTTAFLAELLNSNVANDLMLLDS 1363

Query: 402  ILERLLTWQGDPEPTVRWLGLLGLGHLALN-RRKVR-HVSTLLPALLGALGEGD----AR 455
            +LE L   Q D   +VR L L GL +LA     KVR H   LL A++G L +GD      
Sbjct: 1364 LLESLAARQKDTCASVRRLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPV 1423

Query: 456  LVGAALGALRRLLLRPRAPVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGG 515
             + A LG  R + L     +R     +  R+ P  D  +   R +++ L G L +   G 
Sbjct: 1424 ALEAMLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHG- 1482

Query: 516  LRLGLRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARC---------DHAFCWGLL 566
                        V+  L PLLL L DP    A +  + L  C           AF   L 
Sbjct: 1483 ---DCEDVFLDQVVGGLAPLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQ 1539

Query: 567  EELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGFLV 626
            E      H+   E L+  C  L+  +P  +   L+    Y +S  + +R AA +  GFLV
Sbjct: 1540 EG--RALHFG--EFLNTTCKHLMHHFPDLLGRLLTTCLFYFKSSWENVRAAAPLFTGFLV 1595

Query: 627  HHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAAAHVSAQQVAMLA 672
             H+ P    Q  LD L   L  L  DP P V   A  +  ++  LA
Sbjct: 1596 LHSEPRQQPQVDLDQLIAALQILLKDPAPEVRTRAAEALGRLVKLA 1641


>gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1710

 Score =  122 bits (306), Expect = 1e-27
 Identities = 135/563 (23%), Positives = 242/563 (42%), Gaps = 34/563 (6%)

Query: 129  QATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSALALEHARDV 188
            +A+V  ++  L+ R + LED+V  ++  +L  +P +      R  +  +  LA  H   +
Sbjct: 1129 KASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETI 1188

Query: 189  VCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQA--------LA 240
            + +LL + LP +   AE+W ++S N      +L  L+  L+    P   A        LA
Sbjct: 1189 LTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLA 1248

Query: 241  ATRALGEMLAVSGCV------GATRGFYPHLLLALVTQLHKLARSPCSPDMPKIWVLSHR 294
            A   L  +  +   +           F P L+  L+ QL    R   +P + K+W L H 
Sbjct: 1249 AVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHT 1308

Query: 295  GPPHSHASC---AVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMV 351
             P     +     +++++ L      + +   +++   W  L    T LEGV LLA   +
Sbjct: 1309 TPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCM 1368

Query: 352  AHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILE--RLLTW 409
             H + H + L   +L  + S     R+++ A    +     +  +L +E +L+   LL  
Sbjct: 1369 QHVEGHRQRLAELVLRGMDSEVLSCRISSTAVCVEMRHRFMSGPVLYQEKLLKPAALLLE 1428

Query: 410  QG---DPEPTVRWLGLLGLGHLALNRRKV--RHVSTLLPALLGALGEGDARLVGA-ALGA 463
            +G   + +  +R L L  LG++AL   K   ++   LL   LG L E  +  V A  + A
Sbjct: 1429 KGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEA 1488

Query: 464  LRRLLLRPR-APVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRG 522
            L ++L   R   V      +  +     D+  + +R  A  L G L R      +   +G
Sbjct: 1489 LTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKG 1548

Query: 523  PLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDSPEALS 582
             ++K    + +PL+L   DP  +AA++   T+ +C H + W  LE     +   + + ++
Sbjct: 1549 EVKK----AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMT 1604

Query: 583  ----HLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDL 638
                 +C  L ++ P  +  FL +T  Y+++    +R AA  L G ++   S   + +  
Sbjct: 1605 VFQTTMCSILTRKKPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLD 1664

Query: 639  LDSLFQDLGRLQSDPKPAVAAAA 661
              +L   L  LQ DP P V  AA
Sbjct: 1665 FPALRNSLQELQLDPDPGVRRAA 1687


>gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1706

 Score =  121 bits (304), Expect = 2e-27
 Identities = 137/563 (24%), Positives = 243/563 (43%), Gaps = 38/563 (6%)

Query: 129  QATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSALALEHARDV 188
            +A+V  ++  L+ R + LED+V  ++  +L  +P +      R  +  +  LA  H   +
Sbjct: 1129 KASVTWIAFFLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETI 1188

Query: 189  VCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQA--------LA 240
            + +LL + LP +   AE+W ++S N      +L  L+  L+    P   A        LA
Sbjct: 1189 LTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLA 1248

Query: 241  ATRALGEMLAVSGCV------GATRGFYPHLLLALVTQLHKLARSPCSPDMPKIWVLSHR 294
            A   L  +  +   +           F P L+  L+ QL    R   +P + K+W L H 
Sbjct: 1249 AVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHT 1308

Query: 295  GPPHSHASC---AVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLLASAMV 351
             P     +     +++++ L      + +   +++   W  L    T LEGV LLA   +
Sbjct: 1309 TPLPEEMNLQRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLLARLCM 1368

Query: 352  AHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILE--RLLTW 409
             H + H + L A+L+ R     D + L+     T +     +  +L +E +L+   LL  
Sbjct: 1369 QHVEGHRQRL-AELVLR---GMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPAALLLE 1424

Query: 410  QG---DPEPTVRWLGLLGLGHLALNRRKV--RHVSTLLPALLGALGEGDARLVGA-ALGA 463
            +G   + +  +R L L  LG++AL   K   ++   LL   LG L E  +  V A  + A
Sbjct: 1425 KGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTAEGMEA 1484

Query: 464  LRRLLLRPR-APVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRG 522
            L ++L   R   V      +  +     D+  + +R  A  L G L R      +   +G
Sbjct: 1485 LTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKKHFFKG 1544

Query: 523  PLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDSPEALS 582
             ++K    + +PL+L   DP  +AA++   T+ +C H + W  LE     +   + + ++
Sbjct: 1545 EVKK----AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTATDDKMT 1600

Query: 583  ----HLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVNQDL 638
                 +C  L ++ P  +  FL +T  Y+++    +R AA  L G ++   S   + +  
Sbjct: 1601 VFQTTMCSILTRKKPAVLYRFLLETMAYVKNNLSRIRIAACNLAGIIMKQMSTHYLKKLD 1660

Query: 639  LDSLFQDLGRLQSDPKPAVAAAA 661
              +L   L  LQ DP P V  AA
Sbjct: 1661 FPALRNSLQELQLDPDPGVRRAA 1683


>gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1723

 Score =  116 bits (291), Expect = 6e-26
 Identities = 141/577 (24%), Positives = 243/577 (42%), Gaps = 52/577 (9%)

Query: 129  QATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRPWRAALRVLSALALEHARDV 188
            +A+V  ++S L+ R + LED+V  ++  +L  +P +      R  +  +  LA  H   +
Sbjct: 1132 KASVTWIASFLQMRAKELEDKVAEILSAILVHLPVVDHPEVRRLLIDGILLLAHHHQETI 1191

Query: 189  VCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQA--------LA 240
            + +LL + LP +   AE+W ++S N      +L  L+  L+    P   A        LA
Sbjct: 1192 LTSLLRQPLPMESHLAEVWLAVSENVPFARTMLHSLMGRLQSRLSPRISATSKADIWRLA 1251

Query: 241  ATRALGEMLAVSGCV------GATRGFYPHLLLALVTQLHKLARSPCSPDMPKIWVLSHR 294
            A   L  +  +   +           F P L+  L+ QL    R   +P + K+W L H 
Sbjct: 1252 AVDPLMTLCTIHLLIQKLDENDKLPDFLPDLIYTLLLQLGSSHRPEAAPPVLKMWKLVHT 1311

Query: 295  GP-PH-------SHASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLLL 346
             P P        S     +++++ L      + +   +++   W  L    T LEGV LL
Sbjct: 1312 TPLPEEMNLQRCSRGRVTIKSMQLLFKRVKSQHLAHTLDEQAVWDLLQDGGTFLEGVSLL 1371

Query: 347  ASAMVAHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTARLLREEVILE-- 404
            A   + H + H + L A+L+ R     D + L+     T +     +  +L +E +L+  
Sbjct: 1372 ARLCMQHVEGHRQRL-AELVLR---GMDSEVLSCRISSTAVCVEFMSGPVLYQEKLLKPA 1427

Query: 405  RLLTWQG---DPEPTVRWLGLLGLGHLALNRRKV--RHVSTLLPALLGALGEGDARLVGA 459
             LL  +G   + +  +R L L  LG++AL   K   ++   LL   LG L E  +  V A
Sbjct: 1428 ALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLREPVSNSVTA 1487

Query: 460  -ALGALRRLLLRPR-APVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLR 517
              + AL ++L   R   V      +  +     D+  + +R  A  L G L R      +
Sbjct: 1488 EGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLARVVGMSKK 1547

Query: 518  LGLRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAFCWGLLEELVTVAHYDS 577
               +G ++K    + +PL+L   DP  +AA++   T+ +C H + W  LE     +   +
Sbjct: 1548 HFFKGEVKK----AWIPLMLHSQDPCSNAAQACMATMFQCVHFWGWKSLEHPSGPSDTTT 1603

Query: 578  PEALSHL---CCRLVQRYPGHVP----------NFLSQTQGYLRSPQDPLRRAAAVLIGF 624
             + ++      C ++ R P   P           FL  T  Y+++    +R AA  L G 
Sbjct: 1604 DDKMTIFQTTMCSILVRKPKGEPAHSEKPAVLYRFLLXTMAYVKNNLSRIRIAACNLAGI 1663

Query: 625  LVHHASPGCVNQDLLDSLFQDLGRLQSDPKPAVAAAA 661
            ++   S   + +    +L   L  LQ DP P V  AA
Sbjct: 1664 IMKQMSTHYLKKLDFPALRNSLQELQLDPDPGVRRAA 1700


>gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
          Length = 1585

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 132/583 (22%), Positives = 231/583 (39%), Gaps = 38/583 (6%)

Query: 120  LEEAGFAGTQATVLTLSSALEARGERLEDQVHALVRGLLAQVPSLAEGRP-WRAALRVLS 178
            LE      T+A  + + + L+ +G  LEDQ+  ++  +   +P L +    ++  L  +S
Sbjct: 1016 LESLNPTCTKACGIWMITVLKQQGAALEDQLLEILGTIYHHMPVLRQKEESFQFILEAIS 1075

Query: 179  ALALEHARDVVCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASGPEPQA 238
             +A  H   VV  LL + LP DR    LW++L+     +G++L  L+  L+     +   
Sbjct: 1076 QIASFHMDTVVVNLLQKPLPFDRDTKTLWKALAEKPASSGKLLQALIDKLETELEDDIAR 1135

Query: 239  LAATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLARSPCSPDMPKI-WVLSHRG-- 295
            + A      M  V     +  G YP L     T L KL        M    W  SHR   
Sbjct: 1136 VEAISVACAMYEVISMGTSVTGLYPELF----TLLLKLVSCTLGQKMLTCPW--SHRRHV 1189

Query: 296  ----------PPHSHASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAHTHLEGVLL 345
                       P   ++  ++ L+A    +G  +     E    W  L    TH  GV  
Sbjct: 1190 MQQGEQQQIPDPCRLSTATLKCLQAQAMREG--LAKESDEGDNLWTLLSSPSTHHIGVCS 1247

Query: 346  LASAMVAHADHHLRGLFADLLPRLRSADDPQRLTAMAFFTGLLQSRPTAR--LLREEVIL 403
            LA +M       +  +   LL  L S+ +  R+T  AFF+ L++     +   LR  +IL
Sbjct: 1248 LARSMAVWQHGVILDIMEQLLSSLTSSSENYRITGAAFFSELMKEPILWKHGNLRNVLIL 1307

Query: 404  ERLLTWQGDPEPTVRWLGLLGLGHLALN--RRKVRHVSTLLPALL-GALGEGDARLVGAA 460
                 W  D   T+R + + GLG+ A     +  +H   +L +++ G        +V  +
Sbjct: 1308 MDQSAW--DSNATLRQMAIRGLGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCES 1365

Query: 461  LGALRRLL-LRPRAPVRLLSAELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLG 519
            L AL+++L L     V     E+  +     +D +D +R +A+ L   L        ++ 
Sbjct: 1366 LKALKKILELLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIF 1425

Query: 520  LRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAF----CWGLLEELVTVAHY 575
                ++K    SL+  LL L DP+     +    L  C         +G+L+ L+     
Sbjct: 1426 FAEEIKK----SLISFLLHLWDPNPKIGVACRDVLMVCIPFLGLQELYGVLDRLLDQDLP 1481

Query: 576  DSPEALSHLCCRLVQRYPGHVPNFLSQTQGYLRSPQDPLRRAAAVLIGFLVHHASPGCVN 635
             + +     C +L ++    +    + +  +  S  + +R AA  L   +V + +   V 
Sbjct: 1482 RARDFYRQFCVKLAKKNQEILWILHTHSFTFFTSTWEVIRSAAVKLTDAVVLNLTSQYVE 1541

Query: 636  QDLLDSLFQDLGRLQSDPKPAVAAAAHVSAQQVAMLARARGCP 678
                + L   L  L+ DP  +V  AA  + Q +    +    P
Sbjct: 1542 LLDREQLTTRLQALRQDPCISVQRAAEAALQTLLRRCKETSIP 1584


>gi|117956387 hypothetical protein LOC80133 [Homo sapiens]
          Length = 573

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 46/193 (23%), Positives = 74/193 (38%), Gaps = 30/193 (15%)

Query: 174 LRVLSALALEHARDVVCALLPRSLPADRVAAELWRSLSRNQRVNGQVLVQLLWALKGASG 233
           L+V++ L     + V+  L+   +PAD    ++W++      V   VL  +L  LKG  G
Sbjct: 316 LQVITLLTCTSPKKVIFQLMDYPVPADDTLIQMWKAACSQASVAPHVLKTILLILKGKPG 375

Query: 234 PEPQA----------------LAATRALGEMLAVSGCVGATRGFYPHLLLALVTQLHKLA 277
                                LAA +AL   L +     A   ++P LL  L+ Q+    
Sbjct: 376 EMEDTVTEGKRFSLDITNLMPLAACQALCTFLPLGSYRKAVAQYFPQLLTTLMFQV--FY 433

Query: 278 RSPCSPDMPKIWVLSHRGPPHSHASCAVEALKALLTGDGGRMVVTCMEQAGGWRRLVGAH 337
            S   P      +L  R      A  A +AL+ LL   G + V   + +   W +L    
Sbjct: 434 NSELKP------ILKDR------ALYAQDALRVLLNCSGLQQVDITLMKENFWDQLSEDL 481

Query: 338 THLEGVLLLASAM 350
            +  GV  +A  +
Sbjct: 482 CYYHGVCFIAKTL 494


>gi|95091988 Rho GTPase activating protein 6 isoform 3 [Homo
           sapiens]
          Length = 765

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 10/68 (14%)

Query: 431 NRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPV-----RLLSAELGP- 484
           ++RK+R   +L PAL+G  G  +A   G+A GA    L  P  P      RL S+  GP 
Sbjct: 28  SKRKLRQTRSLDPALIGGCGSDEAGAEGSARGATAGRLYSPSLPAESLGPRLASSSRGPP 87

Query: 485 ----RLPP 488
               RLPP
Sbjct: 88  PRATRLPP 95


>gi|95091875 Rho GTPase activating protein 6 isoform 1 [Homo
           sapiens]
          Length = 974

 Score = 38.9 bits (89), Expect = 0.017
 Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 10/68 (14%)

Query: 431 NRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPV-----RLLSAELGP- 484
           ++RK+R   +L PAL+G  G  +A   G+A GA    L  P  P      RL S+  GP 
Sbjct: 28  SKRKLRQTRSLDPALIGGCGSDEAGAEGSARGATAGRLYSPSLPAESLGPRLASSSRGPP 87

Query: 485 ----RLPP 488
               RLPP
Sbjct: 88  PRATRLPP 95


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 38.1 bits (87), Expect = 0.029
 Identities = 42/141 (29%), Positives = 59/141 (41%), Gaps = 29/141 (20%)

Query: 38   PPSAGPQPKSWEVKPEAEPQTQ-------ALTAPSEAEPGRGATVPE--AGSEPCSLNSA 88
            PP+  P   S  +  E EP+         AL A  EAE     TVPE  A  +P   +S+
Sbjct: 2187 PPALPPDQASTRLPAELEPEPSGEPKLDVALEAAVEAE-----TVPEERARGDP---DSS 2238

Query: 89   LEPAPEGPHQVPQSSWEEGVLADLALYTAACLEEAGFAGTQATVLTLSSALEARGERLED 148
            +EPAP  P Q P  S ++G  A+     + C  +           T++ A  A G   ED
Sbjct: 2239 VEPAPVPPEQRPLGSGDQGAEAEGPPAASLCAPDGPAPN------TVAQAQAADGAGPED 2292

Query: 149  QVHALVRGLLAQVPSLAEGRP 169
               A      ++  + AEG P
Sbjct: 2293 DTEA------SRAAAPAEGPP 2307


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 38.1 bits (87), Expect = 0.029
 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 4/81 (4%)

Query: 25  TEGIRARQGQPQGPPSAG---PQ-PKSWEVKPEAEPQTQALTAPSEAEPGRGATVPEAGS 80
           ++G   R G+P+GPPS G   PQ P     KP+  P  +         PGR    P  G 
Sbjct: 215 SQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGG 274

Query: 81  EPCSLNSALEPAPEGPHQVPQ 101
            P          P+GP   PQ
Sbjct: 275 NPQQPLPPPAGKPQGPPPPPQ 295



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 27/82 (32%), Positives = 33/82 (40%), Gaps = 12/82 (14%)

Query: 25  TEGIRARQGQPQGPP------SAGPQPKSWEVKPEAEPQTQALTAPSEAEPGRGATVPEA 78
           ++G   R G+P+GPP      S GP P+    KPE  P +Q    P    P  G      
Sbjct: 194 SQGPPPRPGKPEGPPPQGGNQSQGPPPRPG--KPEG-PPSQGGNKPQGPPPHPG---KPQ 247

Query: 79  GSEPCSLNSALEPAPEGPHQVP 100
           G  P   N    P P G  Q P
Sbjct: 248 GPPPQEGNKPQRPPPPGRPQGP 269



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 9/79 (11%)

Query: 25  TEGIRARQGQPQGPP------SAGPQPKSWEVKPEAE-PQTQALTAPSEAEPGRGATVPE 77
           ++G   R G+P+GPP      S GP P+    KPE + PQ    +      PG+    P 
Sbjct: 68  SQGPPPRPGKPEGPPPQGGNQSQGPPPRPG--KPEGQPPQGGNQSQGPPPRPGKPEGPPP 125

Query: 78  AGSEPCSLNSALEPAPEGP 96
            G             PEGP
Sbjct: 126 QGGNQSQGPPPRPGKPEGP 144


>gi|4503121 cardiotrophin 1 isoform 1 [Homo sapiens]
          Length = 201

 Score = 37.7 bits (86), Expect = 0.037
 Identities = 49/159 (30%), Positives = 64/159 (40%), Gaps = 21/159 (13%)

Query: 371 SADDPQRLTAMAFFTGL----LQSRPTARLLRE--EVILERLLTWQGDPEPTVRWLGLLG 424
           S +DPQ  ++++    L     Q+   A LL +  E +L+  +  QGDP          G
Sbjct: 7   SLEDPQTDSSVSLLPHLEAKIRQTHSLAHLLTKYAEQLLQEYVQLQGDP---------FG 57

Query: 425 LGHLALNRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLLSAELGP 484
           L   +  R  V  +S   P+  G       RL  AAL AL  LL      V    AEL P
Sbjct: 58  LPSFSPPRLPVAGLSAPAPSHAGLPVHERLRLDAAALAALPPLL----DAVCRRQAELNP 113

Query: 485 RLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRGP 523
           R P LL    D+ R +    LG  V      L    RGP
Sbjct: 114 RAPRLLRRLEDAARQARA--LGAAVEALLAALGAANRGP 150


>gi|169171388 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 154

 Score = 37.4 bits (85), Expect = 0.049
 Identities = 32/97 (32%), Positives = 37/97 (38%), Gaps = 19/97 (19%)

Query: 3   GGVWGRSRAREAPVGALTLTALTEGIRARQGQPQGP---PSAGPQPKSWEVKPEAEPQTQ 59
           GG  G  RARE               RA  G+P G    P A P PK ++    A  +  
Sbjct: 63  GGAGGAGRARE---------------RAESGRPCGRRRHPQAEPAPKEFQ-GDGAAARAD 106

Query: 60  ALTAPSEAEPGRGATVPEAGSEPCSLNSALEPAPEGP 96
           ALTA   AEP  G    E G E  S   +      GP
Sbjct: 107 ALTAGKSAEPAPGGEGGERGEESASERESERAPGRGP 143


>gi|239749096 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 154

 Score = 37.4 bits (85), Expect = 0.049
 Identities = 32/97 (32%), Positives = 37/97 (38%), Gaps = 19/97 (19%)

Query: 3   GGVWGRSRAREAPVGALTLTALTEGIRARQGQPQGP---PSAGPQPKSWEVKPEAEPQTQ 59
           GG  G  RARE               RA  G+P G    P A P PK ++    A  +  
Sbjct: 63  GGAGGAGRARE---------------RAESGRPCGRRRHPQAEPAPKEFQ-GDGAAARAD 106

Query: 60  ALTAPSEAEPGRGATVPEAGSEPCSLNSALEPAPEGP 96
           ALTA   AEP  G    E G E  S   +      GP
Sbjct: 107 ALTAGKSAEPAPGGEGGERGEESASERESERAPGRGP 143


>gi|239743123 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 123

 Score = 37.4 bits (85), Expect = 0.049
 Identities = 32/97 (32%), Positives = 37/97 (38%), Gaps = 19/97 (19%)

Query: 3   GGVWGRSRAREAPVGALTLTALTEGIRARQGQPQGP---PSAGPQPKSWEVKPEAEPQTQ 59
           GG  G  RARE               RA  G+P G    P A P PK ++    A  +  
Sbjct: 32  GGAGGAGRARE---------------RAESGRPCGRRRHPQAEPAPKEFQ-GDGAAARAD 75

Query: 60  ALTAPSEAEPGRGATVPEAGSEPCSLNSALEPAPEGP 96
           ALTA   AEP  G    E G E  S   +      GP
Sbjct: 76  ALTAGKSAEPAPGGEGGERGEESASERESERAPGRGP 112


>gi|12751477 forkhead box L2 [Homo sapiens]
          Length = 376

 Score = 36.6 bits (83), Expect = 0.083
 Identities = 28/84 (33%), Positives = 32/84 (38%), Gaps = 2/84 (2%)

Query: 11  AREAPVGALTLTALTEGIRARQGQPQGPPSAGPQPKSWEVKPEAEPQTQALTAPSEAEPG 70
           A   P   +   AL  G+        GPP+A P P      P A     A  AP  A P 
Sbjct: 253 ASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAH-HLHAAAAPPPAPPH 311

Query: 71  RGATVPEAGS-EPCSLNSALEPAP 93
            GA  P  G   P S  +A  PAP
Sbjct: 312 HGAAAPPPGQLSPASPATAAPPAP 335


>gi|156416026 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 36.6 bits (83), Expect = 0.083
 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 3/62 (4%)

Query: 23  ALTEGIRARQGQPQGPPSAGPQPKSW-EVKPEAEPQTQALTAPSEAEPGRGATVPEAGSE 81
           A T      Q QPQ PP   P+P+S  + +PE EP+ +A   P+ A P      PE   +
Sbjct: 220 AATSAAPPPQPQPQPPPQ--PEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQ 277

Query: 82  PC 83
            C
Sbjct: 278 VC 279


>gi|156415998 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 36.6 bits (83), Expect = 0.083
 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 3/62 (4%)

Query: 23  ALTEGIRARQGQPQGPPSAGPQPKSW-EVKPEAEPQTQALTAPSEAEPGRGATVPEAGSE 81
           A T      Q QPQ PP   P+P+S  + +PE EP+ +A   P+ A P      PE   +
Sbjct: 220 AATSAAPPPQPQPQPPPQ--PEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQ 277

Query: 82  PC 83
            C
Sbjct: 278 VC 279


>gi|156415996 zinc finger protein 219 [Homo sapiens]
          Length = 722

 Score = 36.6 bits (83), Expect = 0.083
 Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 3/62 (4%)

Query: 23  ALTEGIRARQGQPQGPPSAGPQPKSW-EVKPEAEPQTQALTAPSEAEPGRGATVPEAGSE 81
           A T      Q QPQ PP   P+P+S  + +PE EP+ +A   P+ A P      PE   +
Sbjct: 220 AATSAAPPPQPQPQPPPQ--PEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQ 277

Query: 82  PC 83
            C
Sbjct: 278 VC 279


>gi|4503969 growth differentiation factor 5 preproprotein [Homo
           sapiens]
          Length = 501

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 31/87 (35%), Positives = 39/87 (44%), Gaps = 10/87 (11%)

Query: 17  GALTLTALTEGIRARQG---QPQG--PPSAGPQPKSWEVKPEAEPQTQALTAPSEAEPGR 71
           GA    A  +G   + G   QP+   P    P+P   E KP   PQT+  TA +    G+
Sbjct: 68  GATNANARAKGGTGQTGGLTQPKKDEPKKLPPRPGGPEPKPGHPPQTRQATARTVTPKGQ 127

Query: 72  ---GATVPEAGSEPCS--LNSALEPAP 93
              G   P+AGS P S  L  A EP P
Sbjct: 128 LPGGKAPPKAGSVPSSFLLKKAREPGP 154


>gi|216548056 cardiotrophin 1 isoform 2 [Homo sapiens]
          Length = 200

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 49/164 (29%), Positives = 65/164 (39%), Gaps = 21/164 (12%)

Query: 366 LPRLRSADDPQRLTAMAFFTGL----LQSRPTARLLRE--EVILERLLTWQGDPEPTVRW 419
           + R   + DPQ  ++++    L     Q+   A LL +  E +L+  +  QGDP      
Sbjct: 1   MSRREGSLDPQTDSSVSLLPHLEAKIRQTHSLAHLLTKYAEQLLQEYVQLQGDP------ 54

Query: 420 LGLLGLGHLALNRRKVRHVSTLLPALLGALGEGDARLVGAALGALRRLLLRPRAPVRLLS 479
               GL   +  R  V  +S   P+  G       RL  AAL AL  LL      V    
Sbjct: 55  ---FGLPSFSPPRLPVAGLSAPAPSHAGLPVHERLRLDAAALAALPPLL----DAVCRRQ 107

Query: 480 AELGPRLPPLLDDTRDSIRASAVGLLGTLVRRGRGGLRLGLRGP 523
           AEL PR P LL    D+ R +    LG  V      L    RGP
Sbjct: 108 AELNPRAPRLLRRLEDAARQARA--LGAAVEALLAALGAANRGP 149


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 4/81 (4%)

Query: 25  TEGIRARQGQPQGPP----SAGPQPKSWEVKPEAEPQTQALTAPSEAEPGRGATVPEAGS 80
           ++G     G+P+GPP    +     +S   KP+  PQ +         PG+    P AG 
Sbjct: 152 SQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGG 211

Query: 81  EPCSLNSALEPAPEGPHQVPQ 101
            P    +     P+GP   PQ
Sbjct: 212 NPQQPQAPPAGKPQGPPPPPQ 232



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 9/79 (11%)

Query: 8   RSRAREAPVGALTLTALTEGIRAR----QGQPQGPPSAGPQPKSWEVKPEAEPQTQALTA 63
           +SR+  +P G        EG + +     G+PQGPP AG  P+  +  P  +PQ      
Sbjct: 172 KSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQ-----G 226

Query: 64  PSEAEPGRGATVPEAGSEP 82
           P     G     P  G +P
Sbjct: 227 PPPPPQGGRPPRPAQGQQP 245


>gi|224451082 cytospin A [Homo sapiens]
          Length = 1117

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 27/71 (38%), Positives = 34/71 (47%), Gaps = 7/71 (9%)

Query: 651 SDPKPAVAAA--AHVSAQQVAMLARARGCPRGPRLLRIAPRPARPPPVFADSPFQRRSVA 708
           S+P P V     +  SA QV   A A   PR P    ++P P + PP  A SP QR S++
Sbjct: 835 SEPTPTVKTLIKSFDSASQVPNPAAA-AIPRTP----LSPSPMKTPPAAAVSPMQRHSIS 889

Query: 709 GRWGCSGPRRA 719
           G    S P  A
Sbjct: 890 GPISTSKPLTA 900


>gi|224451080 cytospin A [Homo sapiens]
          Length = 1117

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 27/71 (38%), Positives = 34/71 (47%), Gaps = 7/71 (9%)

Query: 651 SDPKPAVAAA--AHVSAQQVAMLARARGCPRGPRLLRIAPRPARPPPVFADSPFQRRSVA 708
           S+P P V     +  SA QV   A A   PR P    ++P P + PP  A SP QR S++
Sbjct: 835 SEPTPTVKTLIKSFDSASQVPNPAAA-AIPRTP----LSPSPMKTPPAAAVSPMQRHSIS 889

Query: 709 GRWGCSGPRRA 719
           G    S P  A
Sbjct: 890 GPISTSKPLTA 900


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 10/64 (15%)

Query: 34   QPQGPPSAGPQPKSWEVKPEAEPQTQALTAPSEAEPGRGATVPEAGSEP----CSLNSAL 89
            QPQ PP   PQP      P+ +PQ Q    P +  P      P    +P    CS+N++ 
Sbjct: 1658 QPQ-PPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPP-----PPPPQQQPPLSQCSMNNSF 1711

Query: 90   EPAP 93
             PAP
Sbjct: 1712 TPAP 1715


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 10/64 (15%)

Query: 34   QPQGPPSAGPQPKSWEVKPEAEPQTQALTAPSEAEPGRGATVPEAGSEP----CSLNSAL 89
            QPQ PP   PQP      P+ +PQ Q    P +  P      P    +P    CS+N++ 
Sbjct: 1658 QPQ-PPPPQPQPAPQPPPPQQQPQQQPQPQPQQPPP-----PPPPQQQPPLSQCSMNNSF 1711

Query: 90   EPAP 93
             PAP
Sbjct: 1712 TPAP 1715


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,979,687
Number of Sequences: 37866
Number of extensions: 1585490
Number of successful extensions: 8082
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 204
Number of HSP's that attempted gapping in prelim test: 7565
Number of HSP's gapped (non-prelim): 654
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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