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Search of human proteins with 154800487
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154800487 ER lipid raft associated 1 [Homo sapiens]
(348 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154800489 ER lipid raft associated 1 [Homo sapiens] 678 0.0
gi|154800487 ER lipid raft associated 1 [Homo sapiens] 678 0.0
gi|6005721 ER lipid raft associated 2 isoform 1 [Homo sapiens] 490 e-139
gi|51242966 ER lipid raft associated 2 isoform 2 [Homo sapiens] 228 6e-60
gi|51242968 ER lipid raft associated 2 isoform 2 [Homo sapiens] 228 6e-60
gi|7661788 mediator complex subunit 4 [Homo sapiens] 39 0.005
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 39 0.009
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 39 0.009
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 38 0.015
gi|221316744 stomatin-like 3 isoform 2 [Homo sapiens] 37 0.034
gi|21686995 stomatin-like 3 isoform 1 [Homo sapiens] 37 0.034
gi|88759339 aster-associated protein [Homo sapiens] 37 0.034
gi|116089284 fibrous sheath interacting protein 1 [Homo sapiens] 37 0.034
gi|6005854 prohibitin 2 isoform 2 [Homo sapiens] 36 0.045
gi|221307584 prohibitin 2 isoform 1 [Homo sapiens] 36 0.045
gi|7657615 podocin [Homo sapiens] 36 0.045
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 36 0.058
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 36 0.058
gi|94557295 mitogen-activated protein kinase 8 interacting prote... 36 0.058
gi|94557297 mitogen-activated protein kinase 8 interacting prote... 36 0.058
gi|38016911 stomatin isoform a [Homo sapiens] 35 0.076
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 35 0.076
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 35 0.076
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 35 0.100
gi|4505257 moesin [Homo sapiens] 35 0.13
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 35 0.13
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 34 0.17
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 34 0.17
gi|94538362 flotillin 2 [Homo sapiens] 34 0.17
gi|197313732 pleckstrin homology-like domain, family B, member 2... 34 0.17
>gi|154800489 ER lipid raft associated 1 [Homo sapiens]
Length = 348
Score = 678 bits (1749), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITT 60
MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITT
Sbjct: 1 MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITT 60
Query: 61 FRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFN 120
FRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFN
Sbjct: 61 FRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFN 120
Query: 121 KIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEA 180
KIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEA
Sbjct: 121 KIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEA 180
Query: 181 IRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKET 240
IRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKET
Sbjct: 181 IRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKET 240
Query: 241 EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFG 300
EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFG
Sbjct: 241 EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFG 300
Query: 301 SNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG 348
SNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG
Sbjct: 301 SNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG 348
>gi|154800487 ER lipid raft associated 1 [Homo sapiens]
Length = 348
Score = 678 bits (1749), Expect = 0.0
Identities = 348/348 (100%), Positives = 348/348 (100%)
Query: 1 MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITT 60
MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITT
Sbjct: 1 MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITT 60
Query: 61 FRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFN 120
FRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFN
Sbjct: 61 FRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFN 120
Query: 121 KIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEA 180
KIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEA
Sbjct: 121 KIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEA 180
Query: 181 IRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKET 240
IRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKET
Sbjct: 181 IRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKET 240
Query: 241 EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFG 300
EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFG
Sbjct: 241 EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFG 300
Query: 301 SNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG 348
SNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG
Sbjct: 301 SNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG 348
>gi|6005721 ER lipid raft associated 2 isoform 1 [Homo sapiens]
Length = 339
Score = 490 bits (1261), Expect = e-139
Identities = 246/309 (79%), Positives = 273/309 (88%)
Query: 3 MTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFR 62
M Q +VA L++++HKIEEGH+ VYYRGGALLTS SGPG+H+MLPFIT+++
Sbjct: 1 MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 60
Query: 63 SVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKI 122
SVQTTLQTDEVKNVPCGTSGGVMIY DRIEVVN L P AV+DIV+NYTADYDK LIFNKI
Sbjct: 61 SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 120
Query: 123 HHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIR 182
HHELNQFCS HTLQEVYIELFDQIDENLK ALQ+DL MAPGL IQAVRVTKP IPEAIR
Sbjct: 121 HHELNQFCSVHTLQEVYIELFDQIDENLKLALQQDLTSMAPGLVIQAVRVTKPNIPEAIR 180
Query: 183 RNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEK 242
RN+ELME+EKTKLLIAAQKQKVVEKEAETERKKA+IEAEK+AQVA+I + QKVMEKETEK
Sbjct: 181 RNYELMESEKTKLLIAAQKQKVVEKEAETERKKALIEAEKVAQVAEITYGQKVMEKETEK 240
Query: 243 RISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSN 302
+ISEIEDAAFLAREKAKADAE Y A K A +NK KLTPEYL+L KY+AIASNSKIYFG +
Sbjct: 241 KISEIEDAAFLAREKAKADAECYTAMKIAEANKLKLTPEYLQLMKYKAIASNSKIYFGKD 300
Query: 303 IPNMFVDSS 311
IPNMF+DS+
Sbjct: 301 IPNMFMDSA 309
>gi|51242966 ER lipid raft associated 2 isoform 2 [Homo sapiens]
Length = 152
Score = 228 bits (581), Expect = 6e-60
Identities = 107/141 (75%), Positives = 120/141 (85%)
Query: 3 MTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFR 62
M Q +VA L++++HKIEEGH+ VYYRGGALLTS SGPG+H+MLPFIT+++
Sbjct: 1 MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 60
Query: 63 SVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKI 122
SVQTTLQTDEVKNVPCGTSGGVMIY DRIEVVN L P AV+DIV+NYTADYDK LIFNKI
Sbjct: 61 SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 120
Query: 123 HHELNQFCSAHTLQEVYIELF 143
HHELNQFCS HTLQEVYIELF
Sbjct: 121 HHELNQFCSVHTLQEVYIELF 141
>gi|51242968 ER lipid raft associated 2 isoform 2 [Homo sapiens]
Length = 152
Score = 228 bits (581), Expect = 6e-60
Identities = 107/141 (75%), Positives = 120/141 (85%)
Query: 3 MTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFR 62
M Q +VA L++++HKIEEGH+ VYYRGGALLTS SGPG+H+MLPFIT+++
Sbjct: 1 MAQLGAVVAVASSFFCASLFSAVHKIEEGHIGVYYRGGALLTSTSGPGFHLMLPFITSYK 60
Query: 63 SVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKI 122
SVQTTLQTDEVKNVPCGTSGGVMIY DRIEVVN L P AV+DIV+NYTADYDK LIFNKI
Sbjct: 61 SVQTTLQTDEVKNVPCGTSGGVMIYFDRIEVVNFLVPNAVYDIVKNYTADYDKALIFNKI 120
Query: 123 HHELNQFCSAHTLQEVYIELF 143
HHELNQFCS HTLQEVYIELF
Sbjct: 121 HHELNQFCSVHTLQEVYIELF 141
>gi|7661788 mediator complex subunit 4 [Homo sapiens]
Length = 270
Score = 39.3 bits (90), Expect = 0.005
Identities = 32/131 (24%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Query: 155 QKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERK 214
+K+ + GL + T+ ++ A+ + E++ E ++L ++ QK+++ E +
Sbjct: 8 EKEKERLGGGLGVAGGNSTRERLLSALE-DLEVLSRELIEMLAISRNQKLLQAGEENQVL 66
Query: 215 KAVI----EAEKIAQVA----KIRFQQKVMEKETEKRISEIEDAAFLAREKAK--ADAEY 264
+ +I E +++ ++A KI + +V+EKE EKR S+I+ +E + A A Y
Sbjct: 67 ELLIHRDGEFQELMKLALNQGKIHHEMQVLEKEVEKRDSDIQQLQKQLKEAEQILATAVY 126
Query: 265 YAAHKYATSNK 275
A K + K
Sbjct: 127 QAKEKLKSIEK 137
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 38.5 bits (88), Expect = 0.009
Identities = 36/120 (30%), Positives = 57/120 (47%), Gaps = 11/120 (9%)
Query: 146 IDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVV 205
IDE +++A + M P + P PE + + +E EKTKL + + +K +
Sbjct: 470 IDEVVRKAKLGTPSNMPPNFPYISSPSVSPPTPEPLHKVYE----EKTKLPSSVEVKKKL 525
Query: 206 EKEAETERKKAVI----EAEKIAQVAKIRFQQKVMEKETEK---RISEIEDAAFLAREKA 258
+KE +T+ KK E EK K + + KV EKE +K R ++ FL E+A
Sbjct: 526 KKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEA 585
Score = 28.5 bits (62), Expect = 9.3
Identities = 25/89 (28%), Positives = 38/89 (42%), Gaps = 8/89 (8%)
Query: 158 LNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAV 217
L L +P + + +P + FE E K K +K+K +KE E E+K+
Sbjct: 663 LPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKE 722
Query: 218 IEAEKIAQVAKIRFQQKVMEKETEKRISE 246
E EK +++ EKE EK E
Sbjct: 723 REKEK--------REREKREKEKEKHKHE 743
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 38.5 bits (88), Expect = 0.009
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 21/192 (10%)
Query: 121 KIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEA 180
K H + F ++ L+ + + E K LQ+D + L ++A R K K+ E
Sbjct: 304 KQHSSTSPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEE 363
Query: 181 IRR-----------NFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKI 229
+R EL E E+ + +K+K ++ + ER+K EA + K
Sbjct: 364 AKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKR 423
Query: 230 RFQQKVMEKETEKRI--SEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKK 287
+ +++ +E EKRI + E F + K A K + K P E+K+
Sbjct: 424 KKEEEKRLREEEKRIKAEKAEITRFFQKPKTP------QAPKTLAGSCGKFAP--FEIKE 475
Query: 288 YQAIASNSKIYF 299
+ +A + F
Sbjct: 476 HMVLAPRRRTAF 487
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 37.7 bits (86), Expect = 0.015
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 2/112 (1%)
Query: 179 EAIRRNFELMEAEKTKLLIAAQKQKVVEKEA-ETERKKAVIEAEKIAQVAKIRFQQKVME 237
+A + E EAE+ + + +K+ E++ + E K+A E ++I + K +++
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359
Query: 238 KETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQ 289
KE EKR +E A A E+ KA E +K KH + ++ +K +
Sbjct: 360 KEEEKRAAEERQRA-RAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVE 410
Score = 31.2 bits (69), Expect = 1.4
Identities = 29/107 (27%), Positives = 50/107 (46%), Gaps = 10/107 (9%)
Query: 188 MEAEKTKLLIAAQKQKVVEKEA-ETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRISE 246
+EAE+ ++++ E+E E K+A E ++I + K +++ KE EKR +E
Sbjct: 295 IEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 354
Query: 247 I-----EDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKY 288
E+ A E+ +A AE K ++K LE KK+
Sbjct: 355 ERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNK----QLEEKKH 397
Score = 29.3 bits (64), Expect = 5.5
Identities = 23/96 (23%), Positives = 45/96 (46%), Gaps = 4/96 (4%)
Query: 186 ELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRIS 245
E EAE+ +L +++ E++ + ++A IEAE+ A +++ E E +R+
Sbjct: 263 ERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ----ERERREAEERERMR 318
Query: 246 EIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPE 281
E E A R++ K + + A + + K E
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 354
>gi|221316744 stomatin-like 3 isoform 2 [Homo sapiens]
Length = 282
Score = 36.6 bits (83), Expect = 0.034
Identities = 45/220 (20%), Positives = 88/220 (40%), Gaps = 14/220 (6%)
Query: 19 VLLYASIHKIEEGHLAVYYRGGALLTSPS-GPGYHIMLPFITTFRSVQTTLQTDEVKNVP 77
+ ++ + I+E AV +R G + + GPG ++LP I F V T +
Sbjct: 36 ISIWMCLKIIKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVDLRTVTCNIPPQE 95
Query: 78 CGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKIHHELNQFCSAHTLQE 137
T V +D + + Y+ V N + T + + L TL +
Sbjct: 96 ILTRDSVTTQVDGVVYYRI---YSAVSAVANVNDVHQATFLLAQT--TLRNVLGTQTLSQ 150
Query: 138 VYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLI 197
+ + ++I +++ L L G+ + V + +IP ++R+ EAE T+
Sbjct: 151 I-LAGREEIAHSIQTLLDDATELW--GIRVARVEIKDVRIPVQLQRSM-AAEAEATR--- 203
Query: 198 AAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVME 237
+ KV+ E E K++ A + + I Q + ++
Sbjct: 204 -EARAKVLAAEGEMNASKSLKSASMVLAESPIALQLRYLQ 242
>gi|21686995 stomatin-like 3 isoform 1 [Homo sapiens]
Length = 291
Score = 36.6 bits (83), Expect = 0.034
Identities = 45/220 (20%), Positives = 88/220 (40%), Gaps = 14/220 (6%)
Query: 19 VLLYASIHKIEEGHLAVYYRGGALLTSPS-GPGYHIMLPFITTFRSVQTTLQTDEVKNVP 77
+ ++ + I+E AV +R G + + GPG ++LP I F V T +
Sbjct: 45 ISIWMCLKIIKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVDLRTVTCNIPPQE 104
Query: 78 CGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKIHHELNQFCSAHTLQE 137
T V +D + + Y+ V N + T + + L TL +
Sbjct: 105 ILTRDSVTTQVDGVVYYRI---YSAVSAVANVNDVHQATFLLAQT--TLRNVLGTQTLSQ 159
Query: 138 VYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLI 197
+ + ++I +++ L L G+ + V + +IP ++R+ EAE T+
Sbjct: 160 I-LAGREEIAHSIQTLLDDATELW--GIRVARVEIKDVRIPVQLQRSM-AAEAEATR--- 212
Query: 198 AAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVME 237
+ KV+ E E K++ A + + I Q + ++
Sbjct: 213 -EARAKVLAAEGEMNASKSLKSASMVLAESPIALQLRYLQ 251
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 36.6 bits (83), Expect = 0.034
Identities = 42/145 (28%), Positives = 70/145 (48%), Gaps = 18/145 (12%)
Query: 145 QIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIR-RNFELMEAEKTKLLIAAQKQK 203
+++E K+ +++ N G +QA K K E ++ +N + E E+ K KQK
Sbjct: 492 RLEEKNKKKTEEE-NAARKGEALQAFEKWKEKKMEYLKEKNRKEREYERAK------KQK 544
Query: 204 VVEKEAETERKKAVIEA-EKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLAREKAKADA 262
E+E E+KK + A EK + + F+QK EK EKR E++ A K D
Sbjct: 545 --EEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEELKRA-------EKKDK 595
Query: 263 EYYAAHKYATSNKHKLTPEYLELKK 287
+ A ++Y ++K E +E K+
Sbjct: 596 DKQAINEYEKWLENKEKQERIERKQ 620
>gi|116089284 fibrous sheath interacting protein 1 [Homo sapiens]
Length = 581
Score = 36.6 bits (83), Expect = 0.034
Identities = 38/132 (28%), Positives = 59/132 (44%), Gaps = 10/132 (7%)
Query: 179 EAIRRNFELMEAEKTKLLI--AAQKQKVVEKEAETERKKAVIE--AEKIAQVAKIRFQQK 234
E + + + E+ K L+ KQK + K +ERKK IE Q+++ +
Sbjct: 394 ENVLESTSCLSEEQLKCLLDECILKQKSIIK-LSSERKKEDIEDVTPVFPQLSRSIISKL 452
Query: 235 VMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSN-KHKLTPEYLELKKYQ---- 289
+ E ET+ + +E+EDA L E+ +A YY N L E +K Q
Sbjct: 453 LNESETKVQKTEVEDADMLESEECEASKGYYLTKALTGHNMSEALVTEAENMKCLQFSKD 512
Query: 290 AIASNSKIYFGS 301
I S++K YF S
Sbjct: 513 VIISDTKDYFMS 524
>gi|6005854 prohibitin 2 isoform 2 [Homo sapiens]
Length = 299
Score = 36.2 bits (82), Expect = 0.045
Identities = 43/226 (19%), Positives = 97/226 (42%), Gaps = 14/226 (6%)
Query: 4 TQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYR--GGALLTSPSGPGYHIMLPFITTF 61
T ++L+ A G VA + S+ +E GH A+++ GG + G H +P+
Sbjct: 21 TALKLLLGA--GAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYP 78
Query: 62 RSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNK 121
+ ++ + P G+ M+ I + V++ + + + DY++ ++ +
Sbjct: 79 IIYDIRARPRKISS-PTGSKDLQMVNIS-LRVLSRPNAQELPSMYQRLGLDYEERVLPSI 136
Query: 122 IHHELNQFCSAHTLQEVYIELFDQIDENLKQALQ---KDLNLMAPGLTIQAVRVTKPKIP 178
++ L + ++ + Q+ +++ L KD +L+ + I + ++
Sbjct: 137 VNEVLKSVVAKFNASQLITQRA-QVSLLIRRELTERAKDFSLILDDVAITELSFSREYTA 195
Query: 179 EAIRRNFELMEAEKTKLLIAA----QKQKVVEKEAETERKKAVIEA 220
+ EA++ + L+ Q+QK+V+ E E E K + EA
Sbjct: 196 AVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEA 241
>gi|221307584 prohibitin 2 isoform 1 [Homo sapiens]
Length = 299
Score = 36.2 bits (82), Expect = 0.045
Identities = 43/226 (19%), Positives = 97/226 (42%), Gaps = 14/226 (6%)
Query: 4 TQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYR--GGALLTSPSGPGYHIMLPFITTF 61
T ++L+ A G VA + S+ +E GH A+++ GG + G H +P+
Sbjct: 21 TALKLLLGA--GAVAYGVRESVFTVEGGHRAIFFNRIGGVQQDTILAEGLHFRIPWFQYP 78
Query: 62 RSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNK 121
+ ++ + P G+ M+ I + V++ + + + DY++ ++ +
Sbjct: 79 IIYDIRARPRKISS-PTGSKDLQMVNIS-LRVLSRPNAQELPSMYQRLGLDYEERVLPSI 136
Query: 122 IHHELNQFCSAHTLQEVYIELFDQIDENLKQALQ---KDLNLMAPGLTIQAVRVTKPKIP 178
++ L + ++ + Q+ +++ L KD +L+ + I + ++
Sbjct: 137 VNEVLKSVVAKFNASQLITQRA-QVSLLIRRELTERAKDFSLILDDVAITELSFSREYTA 195
Query: 179 EAIRRNFELMEAEKTKLLIAA----QKQKVVEKEAETERKKAVIEA 220
+ EA++ + L+ Q+QK+V+ E E E K + EA
Sbjct: 196 AVEAKQVAQQEAQRAQFLVEKAKQEQRQKIVQAEGEAEAAKMLGEA 241
>gi|7657615 podocin [Homo sapiens]
Length = 383
Score = 36.2 bits (82), Expect = 0.045
Identities = 47/227 (20%), Positives = 96/227 (42%), Gaps = 18/227 (7%)
Query: 21 LYASIHKIEEGHLAVYYRGGALLTSPS-GPGYHIMLPFITTFRSVQTTLQTDEVKNVPCG 79
++ + ++E + +R G LL + GPG LP + T+ V LQT E+
Sbjct: 121 IWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEIV 180
Query: 80 TSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKIHHELNQFCSAHTLQEVY 139
T ++ ID I M ++ + A K + F + + + + +L E+
Sbjct: 181 TKDMFIMEIDAICYYRM----ENASLLLSSLAHVSKAVQF-LVQTTMKRLLAHRSLTEIL 235
Query: 140 IELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAA 199
+E I ++ K AL D G+ ++ + + ++P ++ + +EAE +
Sbjct: 236 LER-KSIAQDAKVAL--DSVTCIWGIKVERIEIKDVRLPAGLQHSL-AVEAEAQR----Q 287
Query: 200 QKQKVVEKEAETERKKAVIEAEKIAQ----VAKIRFQQKVMEKETEK 242
K +++ EAE +++ A +I ++R+ + TEK
Sbjct: 288 AKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEK 334
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 35.8 bits (81), Expect = 0.058
Identities = 28/90 (31%), Positives = 47/90 (52%), Gaps = 11/90 (12%)
Query: 213 RKKAVIEAEKIAQVAKIRFQ----QKVMEKETEKRISEIEDAAFLAREKAKADAEY---- 264
+K I AE +QV +IR Q QK +E++TE R+ ++D R+KA+ + EY
Sbjct: 8 KKDKEIIAEYESQVKEIRAQLVEQQKCLEQQTEMRVQLLQDLQDFFRKKAEIETEYSRNL 67
Query: 265 -YAAHKYATSNKHKLTPEYLELKKYQAIAS 293
A ++ K + T ++ + KK Q + S
Sbjct: 68 EKLAERFMA--KTRSTKDHQQYKKDQNLLS 95
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 35.8 bits (81), Expect = 0.058
Identities = 24/85 (28%), Positives = 49/85 (57%), Gaps = 4/85 (4%)
Query: 179 EAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEK 238
EAI++ ++++ +K L A++ + +K+AE K+ +E E A K++ + ++K
Sbjct: 3 EAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQ--LEDELAAMQKKLKGTEDELDK 60
Query: 239 ETEKRISEIEDAAFLAREKAKADAE 263
+E + + ++ LA +KA ADAE
Sbjct: 61 YSE-ALKDAQEKLELAEKKA-ADAE 83
>gi|94557295 mitogen-activated protein kinase 8 interacting protein
3 isoform 2 [Homo sapiens]
Length = 1330
Score = 35.8 bits (81), Expect = 0.058
Identities = 23/101 (22%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 176 KIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAE-KIAQVAKIRFQQK 234
++ + N +L+E TK + K ++ K + ++ V+ E + A+ AK++ + +
Sbjct: 413 EVGNLLLENSQLLE---TKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENR 469
Query: 235 VMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNK 275
+ KE E+ + ++ A +AR + K +AE +++ S+K
Sbjct: 470 I--KELEEELKRVKSEAIIARREPKEEAEDVSSYLCTESDK 508
Score = 33.1 bits (74), Expect = 0.38
Identities = 37/167 (22%), Positives = 66/167 (39%), Gaps = 35/167 (20%)
Query: 186 ELMEAEKTKLLIAAQKQKVVEKEAETE--RKKAVIEAEK---IAQVAKIRFQQKVMEKET 240
EL+ + +LL +++K + ++AE + + +E EK QV FQ + +E +
Sbjct: 81 ELLREDNEQLLTQYEREKALRRQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKA 140
Query: 241 EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFG 300
+ +I + L +++ EY A H+ T E++E K Q + NS+
Sbjct: 141 KNYADQI---SRLEERESEMKKEYNALHQRHTEMIQTYV-EHIERSKMQQVGGNSQ---- 192
Query: 301 SNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKEST 347
ESSLP + P+ NV + T
Sbjct: 193 ----------------------TESSLPGRRKERPTSLNVFPLADGT 217
>gi|94557297 mitogen-activated protein kinase 8 interacting protein
3 isoform 1 [Homo sapiens]
Length = 1336
Score = 35.8 bits (81), Expect = 0.058
Identities = 23/101 (22%), Positives = 53/101 (52%), Gaps = 6/101 (5%)
Query: 176 KIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAE-KIAQVAKIRFQQK 234
++ + N +L+E TK + K ++ K + ++ V+ E + A+ AK++ + +
Sbjct: 419 EVGNLLLENSQLLE---TKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENR 475
Query: 235 VMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNK 275
+ KE E+ + ++ A +AR + K +AE +++ S+K
Sbjct: 476 I--KELEEELKRVKSEAIIARREPKEEAEDVSSYLCTESDK 514
Score = 33.1 bits (74), Expect = 0.38
Identities = 37/167 (22%), Positives = 66/167 (39%), Gaps = 35/167 (20%)
Query: 186 ELMEAEKTKLLIAAQKQKVVEKEAETE--RKKAVIEAEK---IAQVAKIRFQQKVMEKET 240
EL+ + +LL +++K + ++AE + + +E EK QV FQ + +E +
Sbjct: 81 ELLREDNEQLLTQYEREKALRRQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKA 140
Query: 241 EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFG 300
+ +I + L +++ EY A H+ T E++E K Q + NS+
Sbjct: 141 KNYADQI---SRLEERESEMKKEYNALHQRHTEMIQTYV-EHIERSKMQQVGGNSQ---- 192
Query: 301 SNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKEST 347
ESSLP + P+ NV + T
Sbjct: 193 ----------------------TESSLPGRRKERPTSLNVFPLADGT 217
>gi|38016911 stomatin isoform a [Homo sapiens]
Length = 288
Score = 35.4 bits (80), Expect = 0.076
Identities = 47/223 (21%), Positives = 89/223 (39%), Gaps = 14/223 (6%)
Query: 19 VLLYASIHKIEEGHLAVYYRGGALLTSPS-GPGYHIMLPFITTFRSVQTTLQTDEVKNVP 77
+ ++ I I+E A+ +R G +L + GPG +LP +F V + ++
Sbjct: 48 ISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQE 107
Query: 78 CGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKIHHELNQFCSAHTLQE 137
T V I +D VV A + AD L+ L L +
Sbjct: 108 ILTKDSVTISVD--GVVYYRVQNATLAVANITNADSATRLL---AQTTLRNVLGTKNLSQ 162
Query: 138 VYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLI 197
+ + ++I N++ L + A G+ ++ V + K+P ++R EAE ++
Sbjct: 163 ILSDR-EEIAHNMQSTLDDATD--AWGIKVERVEIKDVKLPVQLQRAM-AAEAEASR--- 215
Query: 198 AAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKET 240
+ KV+ E E +A+ EA + + Q + ++ T
Sbjct: 216 -EARAKVIAAEGEMNASRALKEASMVITESPAALQLRYLQTLT 257
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 35.4 bits (80), Expect = 0.076
Identities = 29/134 (21%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Query: 179 EAIRRNF-----ELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQ 233
EA+RR +L E E+ K + A++QK +E++ E R+ + + + +Q
Sbjct: 368 EALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQ 427
Query: 234 KVMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPE--YLELKKYQAI 291
+ E+E ++R+ E+E E+ +A+ E + + +L E +LE+ + Q +
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487
Query: 292 ASNSKIYFGSNIPN 305
+ + P+
Sbjct: 488 QEQAMLLHDHRRPH 501
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 35.4 bits (80), Expect = 0.076
Identities = 29/134 (21%), Positives = 62/134 (46%), Gaps = 7/134 (5%)
Query: 179 EAIRRNF-----ELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQ 233
EA+RR +L E E+ K + A++QK +E++ E R+ + + + +Q
Sbjct: 368 EALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQ 427
Query: 234 KVMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPE--YLELKKYQAI 291
+ E+E ++R+ E+E E+ +A+ E + + +L E +LE+ + Q +
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487
Query: 292 ASNSKIYFGSNIPN 305
+ + P+
Sbjct: 488 QEQAMLLHDHRRPH 501
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 35.0 bits (79), Expect = 0.100
Identities = 27/116 (23%), Positives = 54/116 (46%), Gaps = 5/116 (4%)
Query: 179 EAIRRNF-----ELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQ 233
EA+RR +L E E+ K + A++QK +E++ E R+ + + + +Q
Sbjct: 368 EALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQ 427
Query: 234 KVMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQ 289
+ E+E ++R+ E+E E+ +A+ E + + +L E L+ Q
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQ 483
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 34.7 bits (78), Expect = 0.13
Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 5/113 (4%)
Query: 187 LMEAEKTKLLIAA-QKQKVV-EKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRI 244
++E EK K +A +K+K+ EKE ER K + E K AQ ++ +E E E++
Sbjct: 322 MLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQERKR 381
Query: 245 SEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKI 297
++ E A LA+E+ +A+ A S K T E L L+ + A S++
Sbjct: 382 AQSE-AEKLAKERQEAEEAKEAL--LQASRDQKKTQEQLALEMAELTARISQL 431
Score = 30.0 bits (66), Expect = 3.2
Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 36/127 (28%)
Query: 168 QAVRVTKPKIPEAIRRNFELMEAEKTKLL-----IAAQKQKVVEK---------EAETER 213
+A+ + K E + E +E EK +L+ I Q +K ++ E E ER
Sbjct: 320 RAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELEEQTRRALELEQER 379
Query: 214 KKAVIEAEKIAQ------------VAKIRFQQKVMEK------ETEKRISEIEDAAFLAR 255
K+A EAEK+A+ + R Q+K E+ E RIS++E +AR
Sbjct: 380 KRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLE----MAR 435
Query: 256 EKAKADA 262
+K +++A
Sbjct: 436 QKKESEA 442
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 34.7 bits (78), Expect = 0.13
Identities = 34/159 (21%), Positives = 71/159 (44%), Gaps = 16/159 (10%)
Query: 134 TLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKT 193
T+++ E + + L + Q+ +++M Q ++ K E R+ EL + +T
Sbjct: 443 TIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQT 502
Query: 194 KLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVA--KIRFQQKVMEKETEK--------- 242
+ ++ KV +++++E K E E+ +A ++ Q+K + E+E
Sbjct: 503 REREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA 562
Query: 243 -----RISEIEDAAFLAREKAKADAEYYAAHKYATSNKH 276
RI E+E + + ++ K ++ A H A NKH
Sbjct: 563 ETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKH 601
Score = 29.3 bits (64), Expect = 5.5
Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 25/184 (13%)
Query: 133 HTLQEVYIELFDQIDENLKQAL--------QKDLNLMAPGLTIQAVRVTKPKIPEAIRRN 184
H E+ E Q+ +KQ QK+ + A ++ T K EA RR
Sbjct: 374 HETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEA-RRK 432
Query: 185 FELMEAEKTKLLIAAQKQKVVEKEAETER-KKAVIEAEKIAQVAKIRFQQKVMEKE---- 239
+ E+ K + +++ + + E R K+ V++ K + +I QK+ EKE
Sbjct: 433 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 492
Query: 240 -------TEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIA 292
+ R E ++ +A EK++++ Y + L E LEL+K +AI
Sbjct: 493 EQELTKKLQTREREFQEQMKVALEKSQSE---YLKISQEKEQQESLALEELELQK-KAIL 548
Query: 293 SNSK 296
+ S+
Sbjct: 549 TESE 552
Score = 28.9 bits (63), Expect = 7.1
Identities = 24/90 (26%), Positives = 41/90 (45%), Gaps = 12/90 (13%)
Query: 186 ELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEA------------EKIAQVAKIRFQQ 233
+L AEKTKL+ + K + ++ E ++ + E E+IAQ+ Q
Sbjct: 335 DLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQM 394
Query: 234 KVMEKETEKRISEIEDAAFLAREKAKADAE 263
+E ++ + E AAF EKA + A+
Sbjct: 395 TTQGEELREQKEKSERAAFEELEKALSTAQ 424
Score = 28.9 bits (63), Expect = 7.1
Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 6/118 (5%)
Query: 183 RNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKET-- 240
++F+ + EK + A+ +K++ E + KA +E +K ++ + K E+E
Sbjct: 1567 QHFQELGEEKDNRVKEAE-EKILTLENQVYSMKAELETKK-KELEHVNLSVKSKEEELKA 1624
Query: 241 -EKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKI 297
E R+ E E AA LA K KA+ + A K S + +Y + + N+K+
Sbjct: 1625 LEDRL-ESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKL 1681
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 34.3 bits (77), Expect = 0.17
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 8/127 (6%)
Query: 144 DQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQK 203
+QI +N K+ +Q + + L + K ++ E + ++ + E+ LL+ Q K
Sbjct: 938 NQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQL-EKVTAEAKIKKMEEEILLLEDQNSK 996
Query: 204 VVEKEAETERKKAVI------EAEKIAQVAKIRFQQKVMEKETEKRISEIEDA-AFLARE 256
++++ E + A E EK +AKIR +Q+VM + E+R+ + E L +
Sbjct: 997 FIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKA 1056
Query: 257 KAKADAE 263
K K D E
Sbjct: 1057 KRKLDGE 1063
Score = 28.9 bits (63), Expect = 7.1
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 31/138 (22%)
Query: 135 LQEVYIELFDQIDENLKQALQKDLNLMAP-----------GLTIQAVRVTKPKIPEAIRR 183
LQ+ EL QIDE Q +K+ L ++ VR + +I E ++
Sbjct: 1067 LQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAE-LQE 1125
Query: 184 NFELMEAEKTKLLIAAQKQK------------VVEKEAETERKKAVIEAEKIAQVAKIRF 231
+FE +A + K A+KQK +E +T + + ++ +VA+++
Sbjct: 1126 DFESEKASRNK----AEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELK- 1180
Query: 232 QQKVMEKETEKRISEIED 249
K +E+ET+ ++I+D
Sbjct: 1181 --KALEEETKNHEAQIQD 1196
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 34.3 bits (77), Expect = 0.17
Identities = 19/70 (27%), Positives = 41/70 (58%), Gaps = 3/70 (4%)
Query: 201 KQKVVEKEAETERKKAVIEAE-KIAQVAKIRFQQKVMEKETEKRISEIEDAAFLAREKAK 259
+++++E R+K + E ++AQV +R++Q+V + E+ + E++D+ REK +
Sbjct: 1193 QEQILEILRFIRREKEIAETRFEVAQVESLRYRQRV--ELLERELQELQDSLNAEREKVQ 1250
Query: 260 ADAEYYAAHK 269
A+ A H+
Sbjct: 1251 VTAKTMAQHE 1260
Score = 32.7 bits (73), Expect = 0.49
Identities = 31/129 (24%), Positives = 60/129 (46%), Gaps = 10/129 (7%)
Query: 141 ELFDQIDENLKQALQKDLN--LMAPGLTIQAVRVTKPKIPEAIRRNFELMEAE----KTK 194
+L D++ ++K+ +Q LN L G + + + +I IRR E+ E + +
Sbjct: 1165 KLSDKVVASVKEGVQGPLNVSLSEEGKSQEQIL----EILRFIRREKEIAETRFEVAQVE 1220
Query: 195 LLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLA 254
L Q+ +++E+E + + E EK+ AK Q + + K+TE +E L
Sbjct: 1221 SLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLR 1280
Query: 255 REKAKADAE 263
EK + + +
Sbjct: 1281 EEKERLEQD 1289
>gi|94538362 flotillin 2 [Homo sapiens]
Length = 428
Score = 34.3 bits (77), Expect = 0.17
Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 15/145 (10%)
Query: 151 KQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEK--- 207
K A +++N+ + A + + + IR+ +E + K IA + Q+++
Sbjct: 223 KSAFSEEVNIKTAEAQL-AYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQEILRTDKE 281
Query: 208 ---------EAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLAREKA 258
EAE R + + E EK+ QV + + + + K E + IE E+
Sbjct: 282 LIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAERM 341
Query: 259 KADAEYYAAHKYATSNKHKLTPEYL 283
K AE Y KY + K L E L
Sbjct: 342 KLKAEAY--QKYGDAAKMALVLEAL 364
>gi|197313732 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 34.3 bits (77), Expect = 0.17
Identities = 32/148 (21%), Positives = 72/148 (48%), Gaps = 14/148 (9%)
Query: 115 KTLIFNKIHHELNQFCSA-----HTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQA 169
K+ +N+ E N + ++ H+ ++ + FD + + +++ ++ +P A
Sbjct: 971 KSEFYNRTASESNVYLNSFHYPDHSYKD---QAFDTLSLDSSDSMETSISACSPDNISSA 1027
Query: 170 VRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEA--ETERKKAVIEAEKIAQVA 227
+I E + R + AEKT+LL + +++ +K A E +R++ ++E + +
Sbjct: 1028 STSNIARIEE-MERLLKQAHAEKTRLLESREREMEAKKRALEEEKRRREILEKRLQEETS 1086
Query: 228 KIRFQQKVMEKETEKRISEIEDAAFLAR 255
+ +QK++EKE + R + A L R
Sbjct: 1087 Q---RQKLIEKEVKIRERQRAQARPLTR 1111
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,439,048
Number of Sequences: 37866
Number of extensions: 468219
Number of successful extensions: 3150
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 203
Number of HSP's that attempted gapping in prelim test: 2687
Number of HSP's gapped (non-prelim): 632
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.